diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fa755bdbdd70cdc52866fd035b6b699a6fbfc2fb --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb593405e0efbb177fa18a7e66f16b40efe9bff0dfafbe494ecea8520afca36e +size 154702 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5c2573d0402125082f6800db61c6bfe9bb2482a3 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:578c07c9d754f7c97acb83684f55be812e6c11265f4cdbb970f5af0b5f4c08c4 +size 88008 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d6b678642b3fa80fc67ce092c176c4a12fcc22fd --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 59, + "title": "Average number of proteins per term", + "value": 2.7966101694915255 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7bc2d667e8dea5bb668c205de6a3218184685eb3 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..660466e6a047d24211b0e76eb18e7d25247adf7c --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +ATP:guanido phosphotransferase active site [IPR022415] 0.8008360704688 2.550248434660536 0.0107646180325795 0.4719453869838656 0.0231872938670673 2 P12277 1 +ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.505225440429986 1.0651175585403136 0.2868227344575367 0.9999999978190188 0.3384508266598933 2 P53597 1 +ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.3966847113397936 0.2593924282682809 0.7953324712114644 1.0 0.8456066525529666 4 P06576 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.2489147759916377 0.2375175373367621 0.8122553155863661 1.0 0.8456066525529666 59 Q13464,P78362,Q00534,Q13177,P24941,O15111,P36507,O14757,Q13555,P54646,P27361,Q16512,P17252,Q7KZI7 14 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..435c2bb6f031e58b877d16eafd32433ffc42f831 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CAPN5", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK3", "MAPK7", "MARK2", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3B", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ATP5B", "CAMK2G", "CDK2", "CDK6", "CHEK1", "CHUK", "CKB", "MAP2K2", "MAPK3", "MARK2", "PAK2", "PKN1", "PRKAA2", "PRKCA", "ROCK1", "SRPK2", "SUCLG1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..dd9aa1e45c0dcd223f6c2f11928a16ff34f0689e --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "IQ motif, EF-hand binding site [IPR000048]", "2": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2e10d3478429a07f0b603b47cab47c43fb7a87b2 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e42d92b4a564f69f99a56bbaf8357678b7e84826b1490b0bc42a3a77f337342 +size 148395 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d1475c50ccb98c7d529be8e16961f680595edd33 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e1d40ea69d11c3d9c7b34f9c343a26ddf4f118fd1a1301c33d5b4e01b8272fb +size 135368 diff --git a/interpro_binding_site/basic/plot_2.png b/interpro_binding_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..1a2431621938c85d97fc74eb35a4f2e2b396b073 --- /dev/null +++ b/interpro_binding_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15d0a058e958e24d668ba6b8ab9e95817b56c759af3cf0283ea2f7e204917de6 +size 147382 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e824c1b18da10d2d29e82d55eeb2f79b7a233226 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44dd2d99c00f8c3c68ea2bd71ac022bd92412c9c077f673aa968e6b525cccdcc +size 80025 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8681963009c8f7f3169336a4cd4bb13d9b88b192 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 4.696969696969697 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dba97b38a37e2b8d846b31c9e79be34a8d8b9b0d --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7252005bf631c24375c9783eaadd198213b33aa3 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hexokinase, binding site [IPR019807] 0.6419826813974348 1.7705913401384186 0.0766286830585714 0.9279854034389678 0.1330919232069924 2 P52789 1 +Peptidase M16, zinc-binding site [IPR001431] 0.6990341062666907 1.494495949534003 0.135046039810561 0.991667626725531 0.2122152054165959 5 P22695 1 +Protein kinase, ATP binding site [IPR017441] 0.3421801879651461 1.2324154558867604 0.2177939302792562 0.9996982835464564 0.2661925814524242 56 P78362,Q13177,Q13043,Q00534,O15111,P24941,P36507,O14757,Q13555,P54646,P27361,Q16512,P17252,Q7KZI7 14 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.509704389369969 1.0881598691857612 0.2765245375028273 0.9999770392747632 0.3259039191997608 2 O75600 1 +IQ motif, EF-hand binding site [IPR000048] 0.5337355624724791 1.050147033985131 0.2936505169955676 0.9999895852741182 0.3341540365811632 10 Q9Y4I1,Q13576,Q15386,P35580,P35579 5 +EF-Hand 1, calcium-binding site [IPR018247] 0.3203513341704041 0.6466497525835893 0.5178586502055091 0.9999999999649446 0.5340417330244313 35 Q15293,P80303,O43852,Q03001,Q14651,Q14257,Q13813 7 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..18bf5bde2e015a3fe243103f8f89bf637f294875 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IRAK1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "CAMK2G", "CDK2", "CDK6", "CHEK1", "CHUK", "DST", "GCAT", "HK2", "IQGAP2", "MAP2K2", "MAPK3", "MARK2", "MYH10", "MYH9", "MYO5A", "NUCB2", "PAK2", "PKN1", "PLS1", "PRKAA2", "PRKCA", "RCN1", "RCN2", "SPTAN1", "SRPK2", "STK4", "UBE3C", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7238e40c1627e98775b47d4d366577e4067d841c --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "FERM conserved site [IPR019747]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Kinesin motor domain, conserved site [IPR019821]", "3": "Chaperonin TCP-1, conserved site [IPR002194]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a1248314f4ddc7f7645b8c022848a772eb786d60 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e58783693e7268fd73a07928ef3e5ecc7ac480808cda78b73439410bb1c0b321 +size 134216 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fabd59bd55762f0f502cc63bd94737eb1552c941 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df489aa71fd2b881e8d4232dcb419a4bd25dc85b6ec3970542bb33ce1c34848f +size 144091 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..31d6dd27f891c228b9cb79a09fe2738f8dd027a9 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7edc97cb856106a271e5ed8321d94ba335380592946780561c77555e836a5d1e +size 152343 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f97bab7ddafda8603cdaf8a4e7d1a86d29d22e43 --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcdca5418033bfbfad04290fb097c6ac2b5a4ae4baccc97a35a6a31609fe091e +size 148748 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c73c80b6c9080f3688a06fb9869e450b788ee21f --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c289345762fcc0ba3c31e69b9275f31bad51ccf80e7864743b2625488df8a06f +size 136490 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0bdf6d66b50f9f1dc11e5da2b1b7ea4129202699 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 281, + "title": "Average number of proteins per term", + "value": 2.8220640569395017 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a5b028c841a142c81fd94e8f083b6411921b9cdd --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1ffba712d52a418c871a79e4f4b68012f8c10b77 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,37 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9868617497760512 3.3849517614343614 0.0007119076424908 0.1813652689995003 0.0046522336637192 2 P30519 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.8805613616004754 2.918127114091531 0.0035214076647327 0.6288919053431699 0.0137432715804153 2 O00429 1 +Ribosomal protein L24/L26, conserved site [IPR005825] 0.8220364287847113 2.6496140863883237 0.0080583759821168 0.8970566736685514 0.0238358279049983 2 P61254 1 +F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.7987458942968058 2.54039076138562 0.0110728677869571 0.956231047427952 0.029403911537813 2 P47755 1 +Hexapeptide transferase, conserved site [IPR018357] 0.7494774559570025 2.3048529214934317 0.0211748120291925 0.9975557628204424 0.0479848562919606 2 Q9Y5P6 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.7369363989250564 2.243928837730523 0.0248369803556287 0.9991474893646668 0.0517630250779094 2 P28340 1 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.7351448193490407 2.2351936362688023 0.0254046390983895 0.9992761651597544 0.0524904675488783 2 Q96FJ2 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.8012455139284487 2.192984744430342 0.0283084782506366 0.9996870433598034 0.0568191599173492 3 P09429 1 +Vinculin, conserved site [IPR000633] 0.7181248133771263 2.1518169561108533 0.0314117738369401 0.999872617093358 0.0621599186491562 2 P35221 1 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.7002090176171971 2.063296695705876 0.0390844478224181 0.9999863683793744 0.0747124478782279 2 Q9H8V3 1 +Polyamine biosynthesis domain, conserved site [IPR030373] 0.6954314720812222 2.039563126546543 0.0413938577988612 0.999993067366002 0.078064926452886 2 P19623 1 +Intermediate filament protein, conserved site [IPR018039] 0.7809165421499366 1.9109470818818224 0.0560113817242202 0.9999999076027593 0.0971555448426289 6 P20700,P08670,Q03252,P07197 4 +FERM conserved site [IPR019747] 0.685134056812331 1.820496365509641 0.0686834492382444 0.9999999979282028 0.1115609782424663 10 P35241,O94887,P35240,P15311,P26038 5 +DnaJ domain, conserved site [IPR018253] 0.6791216378689574 1.7107004448696554 0.0871364255464137 0.9999999999925174 0.1345348108711113 9 Q9UBS4,Q9NVH1,Q96KC8,Q99543 4 +ABC transporter-like, conserved site [IPR017871] 0.6886584814168653 1.6824128365762046 0.0924888139400081 0.9999999999985664 0.1394499728744561 8 P08183,Q9NRK6,Q9UG63,P28288 4 +Ubiquitin conserved site [IPR019954] 0.6201851298895087 1.6592645800310335 0.0970624893110532 0.9999999999996534 0.143708246657815 2 P46379 1 +DNA ligase, ATP-dependent, conserved site [IPR016059] 0.6195879366975218 1.656203106594698 0.0976806943474828 0.999999999999714 0.143708246657815 2 P18858 1 +Mrp, conserved site [IPR000808] 0.6717443249701237 1.6004578164034278 0.109497057836061 0.999999999999993 0.1577880679586315 3 Q9Y5Y2,Q8TB37 2 +Mini-chromosome maintenance, conserved site [IPR018525] 0.7037773713773888 1.5688271582423774 0.1166882184179809 0.9999999999999992 0.1639469468772632 6 Q14566,P33992,P25205 3 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.5023669107479711 1.2833043384162246 0.1993854733388156 1.0 0.2501219553937821 16 P18074,Q12873,Q9H2U1,Q7Z478,P54132,Q86WJ1,O60231,Q92620 8 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.6430504470412102 1.2471307213020908 0.2123495700332931 1.0 0.2640275627405105 5 P42345,Q9UBF8 2 +Syntaxin/epimorphin, conserved site [IPR006012] 0.6397447500369653 1.1878227023613948 0.2349032682027769 1.0 0.2869905146303492 4 Q9P2W9,Q12846 2 +ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.505225440429986 1.0651175585403136 0.2868227344575367 1.0 0.3459106797535099 2 P53597 1 +Cullin, conserved site [IPR016157] 0.599002594046584 1.0529075163350743 0.2923833809082672 1.0 0.3511099574154833 5 Q13620,Q93034,Q13618 3 +Thioredoxin, conserved site [IPR017937] 0.52085971176478 0.9847536934418518 0.3247450714274131 1.0 0.3802223544629295 10 O95881,Q8IXB1,Q9H1E5,Q9H3N1 4 +Tubulin, conserved site [IPR017975] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.3869263436598151 7 P04350 1 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.4640191101821473 0.8559208318647358 0.3920415713255401 1.0 0.4478198436686047 2 P10644 1 +Kinesin motor domain, conserved site [IPR019821] 0.3758732123799997 0.4638548909664451 0.6427517132742806 1.0 0.7027752195722679 14 Q9Y496,P33176,Q99661,O00139,Q9BW19,O95235 6 +Ribosomal S11, conserved site [IPR018102] 0.3529411764705867 0.3574447859082388 0.7207588539190626 1.0 0.7759894174377647 2 P82912 1 +Ribosomal protein L3, conserved site [IPR019926] 0.2911316810988251 0.1677947493100215 0.86674475337795 1.0 0.9087883421612089 2 P39023 1 +Chromo domain, conserved site [IPR023779] 0.3310604004648739 0.1475981432539733 0.8826599205199663 1.0 0.9186201395041133 8 P83916,Q12873,Q13185 3 +Zinc finger, RING-type, conserved site [IPR017907] 0.2707309190583113 0.1213462796229965 0.9034167649858558 1.0 0.9308607325696898 20 Q8TDB6,O15344,O95376,Q5VTR2 4 +EGF-like, conserved site [IPR013032] 0.2657509704389262 0.1158069805677647 0.907805518049924 1.0 0.9308607325696898 2 O94813 1 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9308607325696898 3 P30876,Q9H9Y6 2 +Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.2803831338859605 0.0672719221055429 0.9463652291528436 1.0 0.953865170863913 12 Q53GQ0,Q9Y394,Q6IAN0,Q06136 4 +Chaperonin TCP-1, conserved site [IPR002194] 0.2620400837571014 0.0317557908558674 0.9746668026253336 1.0 0.9746668026253336 8 P49368,P50991,Q99832,P17987,P50990,P40227,P78371 7 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..62234ea2aec0d4cc730705d9761a613658bc0853 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CECR2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CREBBP", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MLH1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "REL", "RELA", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SH3RF1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN", "STRN3", "STX12", "STX18", "STX4", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB10", "ABCD3", "ABCF2", "ARIH2", "BAG6", "BLM", "CAPZA2", "CBX1", "CBX3", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CHD1L", "CHD3", "CTNNA1", "CUL3", "CUL4B", "CUL5", "DHRS7", "DHRS7B", "DHX16", "DHX29", "DHX36", "DHX38", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNM1L", "DTX3L", "DYNLL2", "ECT2", "ERCC2", "EZR", "FARP2", "GMPPB", "HMGB1", "HMOX2", "HSD17B12", "KDSR", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "LIG1", "LMNB1", "LMNB2", "MCM3", "MCM5", "MCM6", "MID1", "MRPS11", "MSN", "MTOR", "NEFM", "NF2", "NUBP2", "NUBPL", "PI4KB", "POLD1", "POLR1B", "POLR2B", "PRKAR1A", "RDX", "RNF20", "RPL26", "RPL3", "SLIT2", "SRM", "STX18", "STX4", "SUCLG1", "TCP1", "TMX1", "TMX4", "TUBB4A", "TXNDC12", "VIM"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9909330f38308d0e4e890a55dccf4a1081b33bd2 --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "FERM, C-terminal PH-like domain [IPR018980]", "1": "FERM, N-terminal [IPR018979]", "2": "DnaJ domain [IPR001623]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ba5945347977d0047378d4c52d007042c6f95d4f --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e7a042a2f39815bbfa85e39adddb527400ff02350e55f7558c5924f1ecc1459 +size 191085 diff --git a/interpro_domain/advanced/plot_1.png b/interpro_domain/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..adc091a7ce779f7c98a198000797522976b2e101 --- /dev/null +++ b/interpro_domain/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7dcda39d28f6239ff0a72f5ce7755e83c85a509646825653e114d8521b91006c +size 189260 diff --git a/interpro_domain/advanced/plot_2.png b/interpro_domain/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5f428a08d6bb2b4cd7b702dc10ddb5577d83c2b7 --- /dev/null +++ b/interpro_domain/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e23e87ca290152a2a93b1d602955bc95896aa9df73c85a750eb4153c05a325f +size 194000 diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bd9c82f529b99c84a49a747db298c0ec8577ec75 --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "FERM, C-terminal PH-like domain [IPR018980]", "1": "FERM, N-terminal [IPR018979]", "2": "DnaJ domain [IPR001623]", "3": "FERM domain [IPR000299]", "4": "Proteasome component (PCI) domain [IPR000717]", "5": "Dbl homology (DH) domain [IPR000219]", "6": "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "7": "Kinesin motor domain [IPR001752]", "8": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "9": "EF-hand domain [IPR002048]", "10": "Protein kinase domain [IPR000719]", "11": "Helicase-associated domain [IPR007502]", "12": "Domain of unknown function DUF1605 [IPR011709]", "13": "Aminotransferase, class I/classII [IPR004839]", "14": "C2 domain [IPR000008]", "15": "AAA+ ATPase domain [IPR003593]", "16": "Pleckstrin homology domain [IPR001849]", "17": "SH3 domain [IPR001452]", "18": "THIF-type NAD/FAD binding fold [IPR000594]", "19": "Phosphoribosyltransferase domain [IPR000836]", "20": "Phox homology [IPR001683]", "21": "Rhodanese-like domain [IPR001763]", "22": "SPRY domain [IPR003877]", "23": "B30.2/SPRY domain [IPR001870]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..508374b2b053ddf8f13510f1674845db9b215c55 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a9f9d718e07e546fac5ff8c14418fc29fb57fce77c3e9321a1897093e2a7380 +size 134818 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..050b30491b400048acd79b91398b0828cdf62961 --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10612f4bae4e3b4f345bf692281a3678ec2ce7b0dbc754e87d7bbf8443aadac4 +size 129055 diff --git a/interpro_domain/basic/plot_10.png b/interpro_domain/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..43afeb34e73ba76356cd71f6149da136c43b173c --- /dev/null +++ b/interpro_domain/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c097baa403503bf6b657dddb341ad7fd07d4731b5b6382c155b6ca94daf8b6c +size 147793 diff --git a/interpro_domain/basic/plot_11.png b/interpro_domain/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..d1746ff5550da03750eb9314b7a8c450a9adefae --- /dev/null +++ b/interpro_domain/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9e5d668b5e6d2b5f914551c6f104180bf245228d85b5a82494bcc3a83967067 +size 144234 diff --git a/interpro_domain/basic/plot_12.png b/interpro_domain/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..ea2c1f460d951b0cea006f920fb8d7770179a594 --- /dev/null +++ b/interpro_domain/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af0569df8a2cb36e8e57f224595c0557a4c3721ca734813b55eb56d479737326 +size 145546 diff --git a/interpro_domain/basic/plot_13.png b/interpro_domain/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..fb4192fa9edbc8c4e3e6f74d08e6881100187bc6 --- /dev/null +++ b/interpro_domain/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:971ffe41513d84c4c6956c9c5570b6768dae4e93d8acb51325eb2dac58fd3a95 +size 143468 diff --git a/interpro_domain/basic/plot_14.png b/interpro_domain/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..9a77ff92825aae586bae7606fa3c8ebbb72bf152 --- /dev/null +++ b/interpro_domain/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0795ce24fe89713f49c526c83ad606b745ada10136480a1f8ac2c98940090511 +size 142634 diff --git a/interpro_domain/basic/plot_15.png b/interpro_domain/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..32cb85fd17e36c7f6db9a5e7bc0fe52cd3521ee8 --- /dev/null +++ b/interpro_domain/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94d7b6b8de926c93d434c3b7c88972075780e6aeec97ed50f9e2a0ca88829909 +size 150473 diff --git a/interpro_domain/basic/plot_16.png b/interpro_domain/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..eff5064115892c7c4e2fb48a1721516ea6533a4b --- /dev/null +++ b/interpro_domain/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1de385ac7b01efeb9864ab0966573b7bd52bd93346af9d44952d76f678a1cb88 +size 151970 diff --git a/interpro_domain/basic/plot_17.png b/interpro_domain/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..80c7a040a9c2e1db821aa99e8aafef0595febcc0 --- /dev/null +++ b/interpro_domain/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40367c3754a50fa6119c3019187057cfa47047c702b93ec4dcbe14fb1da413b6 +size 142546 diff --git a/interpro_domain/basic/plot_18.png b/interpro_domain/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..2ae2fda020dd4736274e2f6ef268aff20f893149 --- /dev/null +++ b/interpro_domain/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6f298ae7ab4e818ac3ec6b5ec0a84bfc66d0ed08f3be03aa0b54e87f190f483 +size 145560 diff --git a/interpro_domain/basic/plot_19.png b/interpro_domain/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..807f75e5f990a42ee72d8bac61992ab42756d8ba --- /dev/null +++ b/interpro_domain/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41f427080382c0b253a73381bf002c6fe8e30d32f04ef24a93cb75a9b2eccf10 +size 151652 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3739f93e873ab9fb6885043b95706320e514031f --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:583d4bd2252fdef8ca7201c26a9d2888f09bfbcc2b72ad7ee20ee44929ee37fa +size 122752 diff --git a/interpro_domain/basic/plot_20.png b/interpro_domain/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..c9717250f6f4fbc8955435f39b0eb823f6121661 --- /dev/null +++ b/interpro_domain/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b68c0383da7264bfff5b034fffc71517f15a48810e27e54b259ffc93e359e019 +size 145837 diff --git a/interpro_domain/basic/plot_21.png b/interpro_domain/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..af05dbbb15a495b6e27c5bca553c5948ef542893 --- /dev/null +++ b/interpro_domain/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9b5372caf59f85dbfa9d799c42d49eed7126b3740f1f6f67f0af4fdd4437d2a +size 142206 diff --git a/interpro_domain/basic/plot_22.png b/interpro_domain/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..080e4725b1d7d4f17446f04d3bebee76395b327f --- /dev/null +++ b/interpro_domain/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7782482a378174eb92cd8878b5093999b36201d898a00c860891ada804cbda0b +size 143960 diff --git a/interpro_domain/basic/plot_23.png b/interpro_domain/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..5c9afa18f08cc33ff309d864b12a4868fedca62a --- /dev/null +++ b/interpro_domain/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60281f5706a64785308eb60ffef4fcbb9f626778935239541233046824d6105c +size 147199 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5a837f1f91db70905aa7445d8cf7776c19f89d8b --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:288dd94a43090a18cb90b0c583cd9f1b5e7ea2f47fb5f205838d647f2d773563 +size 129459 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..cbc8150c7bea181ca2f8e6964c8ec43a81eff7d8 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d88353dc81e08571e3b66b5fbaf4632af824bf6afa785a3a39b7d714f676ee5e +size 147211 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..fbe17f444dc9abee989a66a7430ebb1116499ade --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:475984547df1cc52f749b34ead16efce3819ef750afefd1f4ad612731a430753 +size 135720 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..746b18c7a10ec2700bf2dfde5647076ce8a27515 --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:145b47272015cc73ab37243aa479a0d0c4ed07b79d56954b8268bbc350dfb4a8 +size 140134 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..815d95ae32f0cc428393999414e3c6ff11f217e6 --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59535aa5e8bef2e90c649028885add34b76f53c37b86aed74879930becc69ec4 +size 143802 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..43b0b65c73d606f00db42175d9ba0ed38e1fb27e --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:01069fbdfb60dfed5d0c4b41c80b67a62c0ed957b0866de74e0009e96dcd9dc6 +size 151681 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..77b44b1bd9c3393403efd8bd4a3250d9a8573f97 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:487b64a0e86acc69af7e505f7ca6833d7acc7d64923b64dc2c28c3a867bb2587 +size 143978 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1996ba3828061d5fc16c3dab0d9536595120c1c0 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95ce303812b3afc26f3a266849e3aa1ed0f1aa9f9004ddfba61131ccf9178043 +size 772029 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a5033596b8b69748189d1eddbbf4977a743035b5 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.0983610682747182 0.0892170338783466 +FERM, C-terminal PH-like domain [IPR018980] 5 9 2.08048619746713 0.0374809603350807 3.8058252427184462 7.347087378640777 -0.3825104465087264 0.4995251419754427 2.006340688854003 1.4307362020105645 0.890146077584761 0.301902540384269 1.0 1.0 0.01180448121602 0.0022722304352638 +FERM, N-terminal [IPR018979] 5 9 2.08048619746713 0.0374809603350807 3.8058252427184462 7.347087378640777 -0.3825104465087264 0.4995251419754427 2.006340688854003 1.4307362020105645 0.890146077584761 0.301902540384269 1.0 1.0 0.01180448121602 0.0022722304352638 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 1 6 2.0633531760026145 0.0390790852402902 2.174757281553398 6.449029126213592 0.6518715826129322 0.4280594236442204 1.299194556056103 1.212725418592039 0.9468550406660212 0.3043162658022956 0.0798652174269664 0.1581956798045988 0.357118555081159 0.2179847922025966 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 1 6 2.0633531760026145 0.0390790852402902 2.2184466019417477 6.415048543689321 0.633554567126164 0.4291196941966081 1.3185935116973673 1.1967053264777463 0.955977613408511 0.304094570424047 0.0583291306653072 0.1169218221283287 0.2731207001200411 0.1297945989547683 +DnaJ domain [IPR001623] 7 17 1.9831535239648832 0.0473502834758099 5.283980582524272 16.95145631067961 0.2877620197190211 0.6553182406991414 3.0031432852689477 2.283876115766552 0.674660578232377 0.2854789848222235 1.0 1.0 0.0678108138951911 0.0396063215160503 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3586a226fd0a58ce66b3d6cf8c0aabf13e820ba6 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 2813, + "title": "Average number of proteins per term", + "value": 2.2076075364379664 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..49180b284fcb0477de05830fad3b2ada160d2701 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b24dea2d9456843206f89be9eef5c1f68db7fba0 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,280 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Intermediate filament head, DNA-binding domain [IPR006821] 0.9728277097641088 3.324799629989757 0.0008848210016858 0.9170985965969324 0.005999514017826 2 P08670 1 +Tim10-like [IPR004217] 0.9590922663481624 3.265502316427795 0.0010927011175554 0.953831097936164 0.006539932433369 2 Q9Y5L4 1 +Potentiating neddylation domain [IPR005176] 0.9199761122723128 3.094280050594453 0.0019729116044051 0.9961330228960532 0.0091429989179435 2 Q9BTE7 1 +EXPERA domain [IPR033118] 0.9190803224843148 3.090317436629732 0.0019994267915346 0.9964114887149632 0.0091751836290162 2 Q5BJF2 1 +RNA binding activity-knot of a chromodomain [IPR025995] 0.9151985667363298 3.073124358544982 0.002118301919642 0.9974332210113728 0.0094487474997258 2 Q9UBU8 1 +FCH domain [IPR001060] 0.8898178560764398 2.9598295806102133 0.0030780926264371 0.9998286886794296 0.012065438297617 2 Q9UKS6 1 +F-BAR domain [IPR031160] 0.8898178560764398 2.9598295806102133 0.0030780926264371 0.9998286886794296 0.012065438297617 2 Q9UKS6 1 +Translation initiation factor IF2/IF5 domain [IPR002735] 0.8874290833084528 2.9490874024381863 0.0031871382626604 0.9998740640833654 0.0124003041948325 2 P55010 1 +Dynamin GTPase effector [IPR003130] 0.8805613616004754 2.918127114091531 0.0035214076647327 0.9999509760622068 0.0130922475363913 2 O00429 1 +GTPase effector domain [IPR020850] 0.8805613616004754 2.918127114091531 0.0035214076647327 0.9999509760622068 0.0130922475363913 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.8805613616004754 2.918127114091531 0.0035214076647327 0.9999509760622068 0.0130922475363913 2 O00429 1 +SAC3/GANP/THP3, conserved domain [IPR005062] 0.8727978501044986 2.882991218214606 0.0039391842249867 0.999984930046223 0.0138684921462924 2 Q96PV6 1 +ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284] 0.8530904747685781 2.7931404690194945 0.0052199019281142 0.9999995960769492 0.0170145818352091 2 P46063 1 +RQC domain [IPR018982] 0.8530904747685781 2.7931404690194945 0.0052199019281142 0.9999995960769492 0.0170145818352091 2 P46063 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8489101224246074 2.7739587218777935 0.0055378704400237 0.999999835659282 0.01776286151401 2 Q5T9A4 1 +Zinc finger, A20-type [IPR002653] 0.8426395939086322 2.745105235480684 0.0060491496453636 0.9999999613196222 0.0188024949750363 2 Q9UJ41 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8268139743206964 2.6718510712432044 0.0075434119087445 0.999999999438302 0.0218401763736286 2 O43390 1 +Ribosomal protein L26/L24, KOW domain [IPR041988] 0.8220364287847113 2.6496140863883237 0.0080583759821168 0.9999999998695512 0.0225554344653679 2 P61254 1 +Hyaluronan-mediated motility receptor, C-terminal [IPR031794] 0.8190504628247279 2.635687024353978 0.008396713902673 0.999999999950034 0.0229097538392039 2 O75330 1 +C2 DOCK-type domain [IPR027007] 0.8077037921767698 2.5825606859809525 0.0098070112835806 0.9999999999990882 0.0255506113447602 2 Q14185 1 +DOCKER domain [IPR027357] 0.8077037921767698 2.5825606859809525 0.0098070112835806 0.9999999999990882 0.0255506113447602 2 Q14185 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8020304568527702 2.555876463312297 0.0105920715775069 0.999999999999902 0.0267991847025314 2 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.8020304568527702 2.555876463312297 0.0105920715775069 0.999999999999902 0.0267991847025314 2 Q13505 1 +ATP:guanido phosphotransferase, N-terminal [IPR022413] 0.8008360704688 2.550248434660536 0.0107646180325795 0.99999999999994 0.0271091052154398 2 P12277 1 +ATP:guanido phosphotransferase, catalytic domain [IPR022414] 0.8008360704688 2.550248434660536 0.0107646180325795 0.99999999999994 0.0271091052154398 2 P12277 1 +Dynamin, GTPase domain [IPR001401] 0.8808243727598546 2.5409961157690777 0.0110537147517302 0.9999999999999736 0.0275412751077211 3 O00429,O60313 2 +Ion transporter-like, CBS domain [IPR044751] 0.7969543147208153 2.5319325898513534 0.0113435796761196 0.9999999999999885 0.0280646346780339 2 Q8NE01 1 +CNNM, transmembrane domain [IPR002550] 0.7969543147208153 2.5319325898513534 0.0113435796761196 0.9999999999999885 0.0280646346780339 2 Q8NE01 1 +MYST, zinc finger domain [IPR040706] 0.7865034338608454 2.4824324320821067 0.0130488812466351 1.0 0.0309473868018311 2 Q92993 1 +Histone acetyltransferase domain, MYST-type [IPR002717] 0.7865034338608454 2.4824324320821067 0.0130488812466351 1.0 0.0309473868018311 2 Q92993 1 +tRNA synthetases class I, catalytic domain [IPR032678] 0.7694834278888979 2.401230124585034 0.0163400569886238 1.0 0.0360862311762397 2 Q9HA77 1 +ERM family, FERM domain C-lobe [IPR041789] 0.922318494173887 2.3782454975691505 0.0173952403323263 1.0 0.0378151553746784 4 P35241,P26038,P15311 3 +ABC-transporter extension domain [IPR032781] 0.760226933412962 2.35676214109133 0.0184350509026787 1.0 0.0394056217243428 2 Q9UG63 1 +Brdt, bromodomain, repeat II [IPR043509] 0.7536578083009826 2.3250741099536136 0.0200679977611513 1.0 0.0416614595587591 2 O60885 1 +Brdt, bromodomain, repeat I [IPR043508] 0.7536578083009826 2.3250741099536136 0.0200679977611513 1.0 0.0416614595587591 2 O60885 1 +NET domain [IPR027353] 0.7536578083009826 2.3250741099536136 0.0200679977611513 1.0 0.0416614595587591 2 O60885 1 +Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346] 0.7414153478650357 2.265732175195685 0.0234677862944967 1.0 0.0468190658485243 2 Q8WXI9 1 +Lamin tail domain [IPR001322] 0.8136200716845837 2.247958449733999 0.0245788395145998 1.0 0.048248622159504 3 P20700,Q03252 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.8728153156317219 2.240228261847668 0.0250761077794481 1.0 0.0489514859011711 5 Q8NB49,Q9HD20 2 +GCF, C-terminal [IPR022783] 0.7360406091370602 2.2395622259546877 0.0251193573339258 1.0 0.0490019085855295 2 Q9UBB9 1 +Exosome complex component, N-terminal domain [IPR025721] 0.734249029561049 2.2308230702524168 0.0256928511415333 1.0 0.0498859170802402 2 Q9Y3B2 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.7282770976410838 2.2016355804361742 0.0276910605059335 1.0 0.0529897640838033 2 O95140 1 +ROCK, Rho binding domain [IPR015008] 0.7199163929531207 2.1606266676822905 0.0307241897179815 1.0 0.0573528909051482 2 Q13464 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.790601143964655 2.1454493055593997 0.0319169405210246 1.0 0.0588271491840516 3 Q9BUJ2 1 +PIK-related kinase [IPR014009] 0.7897677935173399 2.1417181405509393 0.0322161700524055 1.0 0.0591541033664599 3 Q9Y4A5 1 +PIK-related kinase, FAT [IPR003151] 0.7897677935173399 2.1417181405509393 0.0322161700524055 1.0 0.0591541033664599 3 Q9Y4A5 1 +FATC domain [IPR003152] 0.7897677935173399 2.1417181405509393 0.0322161700524055 1.0 0.0591541033664599 3 Q9Y4A5 1 +Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543] 0.7154374440131412 2.1385878527242252 0.0324690621538641 1.0 0.0593377175813848 2 Q13555 1 +Alpha/beta hydrolase fold-1 [IPR000073] 0.8628870166252882 2.1371622890961492 0.0325847940855759 1.0 0.0593659493281897 4 Q9NUJ1 1 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.7133472678411479 2.1282865275692933 0.0333133344347134 1.0 0.0604193486556085 2 Q5T160 1 +DALR anticodon binding [IPR008909] 0.7133472678411479 2.1282865275692933 0.0333133344347134 1.0 0.0604193486556085 2 Q5T160 1 +NOPS [IPR012975] 0.7843488649940192 2.1174221543833593 0.0342240356016907 1.0 0.0617525414673226 3 Q15233,Q8WXF1 2 +Methyltransferase type 11 [IPR013216] 0.7082711257091563 2.1032254418234357 0.0354460673118586 1.0 0.0632676315661537 2 Q6FI81 1 +Ribosome receptor lysine/proline rich [IPR007794] 0.7049865631531753 2.0869767284740104 0.0368902382071623 1.0 0.065224538074637 2 Q86UP2 1 +FERM, C-terminal PH-like domain [IPR018980] 0.75591931784849 2.08048619746713 0.0374809603350807 1.0 0.0657888595941269 9 P35241,O94887,P35240,P15311,P26038 5 +FERM, N-terminal [IPR018979] 0.75591931784849 2.08048619746713 0.0374809603350807 1.0 0.0657888595941269 9 P35241,O94887,P35240,P15311,P26038 5 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.8159773381846545 2.0633531760026145 0.0390790852402902 1.0 0.0679054640419667 6 Q32P28 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.8159773381846545 2.0633531760026145 0.0390790852402902 1.0 0.0679054640419667 6 Q32P28 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.696625858465199 2.0455015097160003 0.0408054405198845 1.0 0.0701195505085126 2 Q10472 1 +Spermidine synthase, tetramerisation domain [IPR035246] 0.6954314720812222 2.039563126546543 0.0413938577988612 1.0 0.0707847550080223 2 P19623 1 +Polyamine biosynthesis domain [IPR030374] 0.6954314720812222 2.039563126546543 0.0413938577988612 1.0 0.0707847550080223 2 P19623 1 +CRIB domain [IPR000095] 0.6867721707972559 1.9964113206994556 0.0458891695792333 1.0 0.0759330788390715 2 Q13177 1 +Citron homology (CNH) domain [IPR001180] 0.6867721707972514 1.9964113206994352 0.0458891695792356 1.0 0.0759330788390715 2 Q8WUH2 1 +Diacylglycerol/phorbol-ester binding [IPR020454] 0.6867721707972312 1.996411320699331 0.0458891695792469 1.0 0.0759330788390715 2 P17252 1 +TRIAD supradomain [IPR044066] 0.6864735742012482 1.9949202633116323 0.046051577102222 1.0 0.0760675786192311 2 O95376 1 +IBR domain [IPR002867] 0.6864735742012482 1.9949202633116323 0.046051577102222 1.0 0.0760675786192311 2 O95376 1 +Ariadne domain [IPR045840] 0.6864735742012482 1.9949202633116323 0.046051577102222 1.0 0.0760675786192311 2 O95376 1 +DnaJ domain [IPR001623] 0.6050676248684151 1.9831535239648832 0.0473502834758099 1.0 0.0774397368706124 17 Q96KC8,Q9NVH1,Q9NVM6,Q8IXB1,Q99543,O75937,Q9UBS4 7 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.6834876082412598 1.9799985664495872 0.0477036897659781 1.0 0.0777915822096791 2 Q9BSJ2 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.6834876082412598 1.9799985664495872 0.0477036897659781 1.0 0.0777915822096791 2 Q9BSJ2 1 +Nucleotidyl transferase domain [IPR005835] 0.7497013142174388 1.9607233762685528 0.0499113006289442 1.0 0.0805972954473134 3 Q9Y5P6,Q9NR50 2 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.748560385414663 1.9555245275226285 0.0505211912423115 1.0 0.0813021229774728 3 Q9H3F6 1 +EF-hand, Ca insensitive [IPR014837] 0.7398446833930648 1.9157310073575704 0.0553993434913531 1.0 0.0872066889989794 3 Q13813,P12814 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.6703493580173019 1.914106531379162 0.0556065451596312 1.0 0.0873861516949959 2 Q96AE4 1 +Intermediate filament, rod domain [IPR039008] 0.7809165421499366 1.9109470818818224 0.0560113817242202 1.0 0.0878750790798837 6 P20700,P08670,Q03252,P07197 4 +Sorting nexin, N-terminal [IPR005329] 0.662585846521353 1.874993644841604 0.0607935978310885 1.0 0.0939112524430818 2 O60749 1 +Sterol-sensing domain [IPR000731] 0.661690056733353 1.870472390734116 0.0614182475210673 1.0 0.0947720955988823 2 O15118 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.6595998805613615 1.859916271146521 0.0628973729080413 1.0 0.0965776801257206 2 P13674 1 +GNAT domain [IPR000182] 0.7922736640862159 1.8430871519218353 0.0653162869078072 1.0 0.0993634023658989 4 P41227 1 +FERM domain [IPR000299] 0.685134056812331 1.820496365509641 0.0686834492382444 1.0 0.1029885622106511 10 P35241,O94887,P35240,P15311,P26038 5 +K Homology domain, type 1 [IPR004088] 0.5369913438878071 1.8160823032857425 0.0693577479137206 1.0 0.1037783749368596 21 Q9Y2W6,Q96PU8,Q15366 3 +Poly(ADP-ribose) polymerase, regulatory domain [IPR004102] 0.6461630337414165 1.7918425817834915 0.0731581856680687 1.0 0.1080283340074947 2 P09874 1 +WGR domain [IPR008893] 0.6461630337414165 1.7918425817834915 0.0731581856680687 1.0 0.1080283340074947 2 P09874 1 +Zinc finger, TFIIB-type [IPR013137] 0.6425798745894288 1.7736292815393158 0.0761244909376228 1.0 0.1114142523452305 2 Q00403 1 +Hexokinase, C-terminal [IPR022673] 0.6419826813974348 1.7705913401384186 0.0766286830585714 1.0 0.1118611756324656 2 P52789 1 +Hexokinase, N-terminal [IPR022672] 0.6419826813974348 1.7705913401384186 0.0766286830585714 1.0 0.1118611756324656 2 P52789 1 +Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.6360107494774424 1.74017511115275 0.0818282744994109 1.0 0.1177406323104056 2 Q16512 1 +Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.6360107494774424 1.74017511115275 0.0818282744994109 1.0 0.1177406323104056 2 Q16512 1 +Sec23, C-terminal [IPR037550] 0.6354135562854597 1.7371298626728766 0.0823642513512545 1.0 0.1182577004329828 2 Q15436 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.6965352449223349 1.7160461099187865 0.0861536033763248 1.0 0.1222755228544913 3 P28340,P09884 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.6965352449223349 1.7160461099187865 0.0861536033763248 1.0 0.1222755228544913 3 P28340,P09884 2 +FERM central domain [IPR019748] 0.6437878574295194 1.694229222316868 0.0902217339538609 1.0 0.1271511711484021 11 P35241,P26038,P15311,P35240 4 +Band 4.1 domain [IPR019749] 0.6437878574295194 1.694229222316868 0.0902217339538609 1.0 0.1271511711484021 11 P35241,P26038,P15311,P35240 4 +Myb domain [IPR017930] 0.6745654742300831 1.6884125277666533 0.0913320672897026 1.0 0.1280743296540047 9 Q96KC8,Q99459 2 +ABC transporter-like, ATP-binding domain [IPR003439] 0.6886584814168653 1.6824128365762046 0.0924888139400081 1.0 0.1287975413926945 8 P08183,Q9NRK6,Q9UG63,P28288 4 +Zinc finger, PARP-type [IPR001510] 0.6195879366975237 1.6562031065947078 0.0976806943474808 1.0 0.13397162028253 2 P09874 1 +DNA ligase, ATP-dependent, C-terminal [IPR012309] 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.13397162028253 2 P18858 1 +DNA ligase, ATP-dependent, N-terminal [IPR012308] 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.13397162028253 2 P18858 1 +DNA ligase, ATP-dependent, central [IPR012310] 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.13397162028253 2 P18858 1 +Ribosomal protein/NADH dehydrogenase domain [IPR007741] 0.673835125448021 1.6102371500059798 0.1073460940722896 1.0 0.1439890856456681 3 O43678,Q8N983 2 +Kinesin-associated [IPR032405] 0.6094356524335649 1.604073613442378 0.1086978273424021 1.0 0.1450507534697236 2 O60333 1 +Kinesin-like KIF1-type [IPR022140] 0.6094356524335649 1.604073613442378 0.1086978273424021 1.0 0.1450507534697236 2 O60333 1 +Zinc finger, CHHC-type [IPR012996] 0.6723416965352382 1.6032524492729503 0.108878930026284 1.0 0.1452235325575803 3 P52597,P31943 2 +CELF1/2, RNA recognition motif 3 [IPR034199] 0.6073454762615733 1.593322177938926 0.1110879338787214 1.0 0.1477495782509897 2 O95319 1 +CELF1/2, RNA recognition motif 2 [IPR034198] 0.6073454762615733 1.593322177938926 0.1110879338787214 1.0 0.1477495782509897 2 O95319 1 +CELF1/2, RNA recognition motif 1 [IPR034196] 0.6073454762615733 1.593322177938926 0.1110879338787214 1.0 0.1477495782509897 2 O95319 1 +CBS domain [IPR000644] 0.7069567693908935 1.583083026604995 0.1134025417411477 1.0 0.1498362376316808 6 P51790,P54619,Q8NE01 3 +K Homology domain [IPR004087] 0.5007524132577945 1.5701268760913167 0.1163855971214835 1.0 0.1529872358423987 21 Q9Y2W6,Q96PU8,Q15366 3 +MCM domain [IPR001208] 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.1530988611985916 6 Q14566,P33992,P25205 3 +MCM, AAA-lid domain [IPR041562] 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.1530988611985916 6 Q14566,P33992,P25205 3 +MCM OB domain [IPR033762] 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.1530988611985916 6 Q14566,P33992,P25205 3 +MCM N-terminal domain [IPR027925] 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.1530988611985916 6 Q14566,P33992,P25205 3 +FAD/NAD(P)-binding domain [IPR023753] 0.6972790687126061 1.5396570516931796 0.1236439708908516 1.0 0.1607257348040507 6 Q9Y6N5 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7193660308709661 1.5320796647611796 0.1255027771763406 1.0 0.162916156989869 4 P08183,P28288 2 +Chromo shadow domain [IPR008251] 0.6498091321179702 1.4975699703305407 0.1342450137227282 1.0 0.1713390306724294 3 P83916 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.6490535903532592 1.494017691314917 0.1351709953176108 1.0 0.1722863660301038 3 Q8WVV9 1 +Peptidase M16, N-terminal [IPR011765] 0.6598312942794601 1.4543170846187252 0.145858415950975 1.0 0.1828430142914852 7 P22695 1 +Peptidase M16, C-terminal [IPR007863] 0.6598312942794601 1.4543170846187252 0.145858415950975 1.0 0.1828430142914852 7 P22695 1 +Peptidase M20, dimerisation domain [IPR011650] 0.5780830098536844 1.4422452033756603 0.1492332125633679 1.0 0.1864089817676528 2 Q96KP4 1 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.6758831367123709 1.3923424372971018 0.1638187264944095 1.0 0.2000964297128849 5 P55769 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.6616603686413556 1.379138418435791 0.1678520805765972 1.0 0.2040666226434648 6 Q9P0V9,Q16181,Q15019,Q14141 4 +JmjC domain [IPR003347] 0.6360312832617966 1.343285483851619 0.1791795506574498 1.0 0.2144554176728791 7 Q8IUF8,Q9NWT6,Q6NYC1 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.6359061410943574 1.3427009561562528 0.1793688249842211 1.0 0.2144554176728791 7 P42345,Q9UBF8,Q9Y4A5 3 +Peptidase M24 [IPR000994] 0.6356452860338975 1.3414825101818983 0.1797638444803808 1.0 0.2147242864217882 7 P53582 1 +Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.614787734360798 1.3325257789773917 0.1826874761854886 1.0 0.2169269187462134 3 P09874 1 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.2178670566706587 3 P20585 1 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.2178670566706587 3 P20585 1 +DNA mismatch repair protein MutS, core [IPR007696] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.2178670566706587 3 P20585 1 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.2178670566706587 3 P20585 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.661027746696145 1.3266584387736475 0.1846216950839883 1.0 0.2182861998945113 5 P51530 1 +Kinesin-like [IPR022164] 0.6096176821983171 1.3081225233320033 0.1908317551109324 1.0 0.2248888676694817 3 Q9Y3P9,O60333 2 +Rho GTPase-activating protein domain [IPR000198] 0.6437810521290219 1.298314951709644 0.1941791306221496 1.0 0.2281645340184239 6 Q13017,Q68EM7,Q07960,Q01968 4 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.6061238723357918 1.2916308520025366 0.1964850144149466 1.0 0.230777597306574 3 Q9UBF8 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.6629817747236346 1.288387379018443 0.1976111498967612 1.0 0.2319066185480139 4 O60749,Q9Y5X3,Q9UNH7 3 +Proteasome component (PCI) domain [IPR000717] 0.4652960071727106 1.2868754330338377 0.1981377093373311 1.0 0.2323307112821644 20 Q7L2H7,Q96PV6,Q9UNM6,O00231,P60228,P48556,Q15008,O60318,O43242,Q5JVF3,Q9UBW8,Q14152,Q9UNS2 13 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.6018041862125638 1.2712422266389316 0.2036424884558374 1.0 0.2385865556127741 3 Q99797 1 +Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.6363470659341706 1.2646970616803264 0.2059799436780092 1.0 0.2412246384538884 6 Q9BW92 1 +PIN domain [IPR002716] 0.5961015321950485 1.244332002457763 0.2133773974510171 1.0 0.249368765695767 3 Q9UPR3 1 +Dbl homology (DH) domain [IPR000219] 0.6133236776084517 1.2371849171804843 0.2160184397192619 1.0 0.2522372165531062 7 O94887,Q92974,Q9H8V3,Q92888,Q9NZM3 5 +HR1 rho-binding domain [IPR011072] 0.6248589936793602 1.1667337952971035 0.2433178904204993 1.0 0.2823651921422709 5 O75116,Q13464,Q16512 3 +ARHGEF1-like, PH domain [IPR041020] 0.5717003797943678 1.1293900150211438 0.2587333431113097 1.0 0.2988981084895746 3 Q92974 1 +Anticodon-binding [IPR004154] 0.6026079883332415 1.1123597853618956 0.2659834880080993 1.0 0.306895632389985 6 Q9BW92,P41250,A2RTX5 3 +F-box domain [IPR001810] 0.6116828977542679 1.1086381825987035 0.2675862994060742 1.0 0.3086183928779364 5 Q8NEZ5 1 +FYVE zinc finger [IPR000306] 0.6042886795732997 1.0761145243287185 0.2818760406915424 1.0 0.3236397152919627 5 Q9P2R3 1 +Zinc finger, FYVE-related [IPR017455] 0.6042886795732997 1.0761145243287185 0.2818760406915424 1.0 0.3236397152919627 5 Q9P2R3 1 +CoA-binding [IPR003781] 0.505225440429986 1.0651175585403136 0.2868227344575367 1.0 0.3290507145306079 2 P53597 1 +Cullin protein, neddylation domain [IPR019559] 0.599002594046584 1.0529075163350743 0.2923833809082672 1.0 0.3351566627933804 5 Q13620,Q93034,Q13618 3 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.5570068063839876 1.048734551324639 0.2943003073987986 1.0 0.3370720681114976 8 Q13464,O14795,O75116,Q92974,P17252 5 +FERM adjacent (FA) [IPR014847] 0.5972258127923962 1.045116347254201 0.295969199579005 1.0 0.3387149546036376 5 O94887 1 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.5004478948940037 1.0405873108435133 0.2980671228933023 1.0 0.3409771519718826 2 Q9UID3 1 +Cullin homology domain [IPR016158] 0.5858691401904214 1.0371619995781576 0.2996603646151974 1.0 0.3425211725569079 6 Q13620,Q93034,Q13618 3 +Chaperone DnaJ, C-terminal [IPR002939] 0.5937278700441747 1.0297926838337013 0.3031073358827829 1.0 0.3460327832760547 5 Q9UBS4 1 +Class I myosin, motor domain [IPR036072] 0.5459649378063228 1.0089481240675724 0.3129995138130277 1.0 0.3557367457858677 3 O94832 1 +Class I myosin tail homology domain [IPR010926] 0.5459649378063228 1.0089481240675724 0.3129995138130277 1.0 0.3557367457858677 3 O94832 1 +High mobility group box domain [IPR009071] 0.4753340710377888 1.0076847440309928 0.3136058312121443 1.0 0.3561458228501259 14 P09429,Q00059 2 +GUCT [IPR012562] 0.4914899970140397 0.9947497714475286 0.3198579809444934 1.0 0.363099475543527 2 Q9BQ39 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.3777513155498886 7 P04350 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.3777513155498886 7 P04350 1 +Rab-GTPase-TBC domain [IPR000195] 0.5534514717524148 0.9590628507194664 0.3375270837207322 1.0 0.380851859810036 7 Q66K14 1 +Syntaxin, N-terminal domain [IPR006011] 0.5308546164394241 0.9388901356088216 0.347787154343476 1.0 0.3918002663869436 3 Q12846 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.3948701055118297 2 P40763 1 +STAT transcription factor, protein interaction [IPR013799] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.3948701055118297 2 P40763 1 +STAT transcription factor, DNA-binding [IPR013801] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.3948701055118297 2 P40763 1 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.5455135369427302 0.9226607120838992 0.3561840460079142 1.0 0.4004579222303208 7 Q9BW92,P49591,P41250 3 +Chromo domain subgroup [IPR017984] 0.5774581766370639 0.920858497002774 0.3571243093908824 1.0 0.4013546473498012 4 P83916 1 +SMARCC, N-terminal [IPR032450] 0.4765601672140921 0.91891972832243 0.3581375601180483 1.0 0.4020115549130367 2 Q8TAQ2 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.4765601672140921 0.91891972832243 0.3581375601180483 1.0 0.4020115549130367 2 Q8TAQ2 1 +SMARCC, C-terminal [IPR032451] 0.4765601672140921 0.91891972832243 0.3581375601180483 1.0 0.4020115549130367 2 Q8TAQ2 1 +Dynamin, N-terminal [IPR045063] 0.5396621288290923 0.895942493801653 0.3702834772481598 1.0 0.4138289318629612 7 P50570,O00429,O60313,O95140 4 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5396621288290923 0.895942493801653 0.3702834772481598 1.0 0.4138289318629612 7 P50570,O00429,O60313,O95140 4 +TGS [IPR004095] 0.5346613275296336 0.8731949741197935 0.3825568137943582 1.0 0.426867242048207 7 Q9BW92 1 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.4640191101821473 0.8559208318647358 0.3920415713255401 1.0 0.4360344733720432 2 P10644 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.4625261272021563 0.8484714529696367 0.3961754641722121 1.0 0.4394485728377101 2 P47897 1 +Sulphate adenylyltransferase [IPR002650] 0.4619289340101558 0.8454949672520098 0.3978345414302171 1.0 0.4402472718501969 2 O43252 1 +ATP-sulfurylase PUA-like domain [IPR025980] 0.4619289340101558 0.8454949672520098 0.3978345414302171 1.0 0.4402472718501969 2 O43252 1 +Sulphate adenylyltransferase catalytic domain [IPR024951] 0.4619289340101558 0.8454949672520098 0.3978345414302171 1.0 0.4402472718501969 2 O43252 1 +SLIDE domain [IPR015195] 0.4610331442221594 0.8410337961544773 0.4003290015190921 1.0 0.442659387292927 2 P28370 1 +ISWI, HAND domain [IPR015194] 0.4610331442221594 0.8410337961544773 0.4003290015190921 1.0 0.442659387292927 2 P28370 1 +STAG [IPR013721] 0.4487906837862043 0.7805256784330128 0.4350815189988044 1.0 0.4792029416380723 2 Q8WVM7 1 +Stromalin conservative domain [IPR020839] 0.4487906837862043 0.7805256784330128 0.4350815189988044 1.0 0.4792029416380723 2 Q8WVM7 1 +Myosin, N-terminal, SH3-like [IPR004009] 0.5292296651588113 0.7528966939451444 0.4515119949612161 1.0 0.4963279569464247 5 Q9Y4I1,P35580 2 +SANT domain [IPR017884] 0.4740172697800739 0.7513963874357674 0.4524141362101646 1.0 0.4971253770153097 10 Q96KC8 1 +Gid-type RING finger domain [IPR044063] 0.4422215586742291 0.7484506643710152 0.4541883726428164 1.0 0.4986853599704304 2 Q7L5Y9 1 +PITH domain [IPR010400] 0.4410271722902321 0.7426513675047878 0.4576927804390642 1.0 0.5023370235564135 2 O43396 1 +TOG domain [IPR034085] 0.5051293622704685 0.7408969361809635 0.4587559333270397 1.0 0.5033075040752585 7 O75122 1 +MPN domain [IPR037518] 0.4559163022808266 0.7132152917656133 0.4757125451759456 1.0 0.5208950523861172 11 O95630 1 +WHEP-TRS domain [IPR000738] 0.5245012684416172 0.701983948693261 0.4826891736273175 1.0 0.5283286558029744 4 P23381 1 +RNA-binding domain, S1 [IPR022967] 0.4821463787838087 0.6979879670792942 0.4851847192633045 1.0 0.5308536037680575 8 Q8N5C6 1 +CDC48, domain 2 [IPR004201] 0.4296805016422793 0.6881047384103681 0.4913868267746206 1.0 0.5353490099601115 2 P55072 1 +CDC48, N-terminal subdomain [IPR003338] 0.4296805016422793 0.6881047384103681 0.4913868267746206 1.0 0.5353490099601115 2 P55072 1 +Kinesin motor domain [IPR001752] 0.4104371886327778 0.6836392640215814 0.4942029845392572 1.0 0.5382086703480181 15 Q9Y496,P33176,Q99661,O00139,Q9BW19,O95235,Q9NS87 7 +Acyl transferase [IPR014043] 0.4237085697223073 0.6598284097101761 0.509363949803729 1.0 0.554076098529733 2 P49327 1 +DMAP1-binding domain [IPR010506] 0.4198268139743159 0.6416241638113591 0.5211172397179653 1.0 0.5659856352612496 2 P26358 1 +KOW [IPR005824] 0.4917459003768397 0.6294722349060065 0.5290399403589459 1.0 0.5743687195020126 6 P61254 1 +Myosin head, motor domain [IPR001609] 0.4647224345930648 0.6204115784850084 0.5349868514438381 1.0 0.5797064765452683 8 Q9Y4I1,P35580,P35579 3 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.4877063746579803 0.6129774909204838 0.5398912231708688 1.0 0.5843455216543494 6 P36915,Q9H089 2 +EF-hand domain, type 2 [IPR015154] 0.4525857892170752 0.5922686229481918 0.5536707235252463 1.0 0.5978793647894503 3 Q9Y4J8 1 +EF-hand domain, type 1 [IPR015153] 0.4525857892170752 0.5922686229481918 0.5536707235252463 1.0 0.5978793647894503 3 Q9Y4J8 1 +Myosin tail [IPR002928] 0.4504703492065203 0.5834786685873838 0.5595711129235508 1.0 0.6035558054654709 3 P35580 1 +Aminoacyl-tRNA synthetase, class II [IPR006195] 0.4075482655949496 0.573428181734783 0.5663548133634699 1.0 0.6100319253031363 13 P49591,P41250,Q9Y285,A2RTX5,Q9BW92 5 +Immunoglobulin subtype 2 [IPR003598] 0.4778623870796515 0.573298314811546 0.5664427262324181 1.0 0.6100319253031363 6 P35613 1 +Immunoglobulin subtype [IPR003599] 0.4778623870796515 0.573298314811546 0.5664427262324181 1.0 0.6100319253031363 6 P35613 1 +EF-hand domain [IPR002048] 0.2990917010923387 0.5669588422759274 0.5707421447616592 1.0 0.6144269625773239 42 Q15293,P80303,O43852,Q03001,Q14651,Q14257,Q13813,Q66K14 8 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.444079991470095 0.5571793629086085 0.5774048882273415 1.0 0.6201756206886261 3 Q86UV5 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.4852106363908087 0.5491965643458011 0.5828705619316563 1.0 0.6255684436145552 4 P51665,Q7L5N1,O00303 3 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.4396654719235201 0.539244153517806 0.5897183977207627 1.0 0.6326765266165162 3 Q14558,O60256 2 +Zinc finger, GATA-type [IPR000679] 0.4791739000867921 0.5267432697620011 0.5983718831512839 1.0 0.6404947135862106 4 Q8WXI9 1 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.3938489101224237 0.5239217453093427 0.6003329695610717 1.0 0.6423494269209946 2 Q8NF37 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.4749550192871686 0.511239707867485 0.6091832173250091 1.0 0.6500881602182286 4 Q96GX9 1 +SANT/Myb domain [IPR001005] 0.3916143167567456 0.4942200837247837 0.6211507574352133 1.0 0.661854954797445 13 Q96KC8,Q99459 2 +AARP2CN [IPR012948] 0.3845924156464562 0.4839936207339278 0.628390396464362 1.0 0.6685560458601553 2 Q2NL82 1 +Bms1/Tsr1-type G domain [IPR030387] 0.3845924156464562 0.4839936207339278 0.628390396464362 1.0 0.6685560458601553 2 Q2NL82 1 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.3845924156464562 0.4839936207339278 0.628390396464362 1.0 0.6685560458601553 2 Q2NL82 1 +Protein kinase domain [IPR000719] 0.2700837014890817 0.4824739564208007 0.6294692949395055 1.0 0.6694507095141131 73 P78362,P24941,Q13043,P36507,O15111,Q00534,O14757,P54646,Q13555,Q6P3W7,P17252,Q7KZI7 12 +Zinc finger, MIZ-type [IPR004181] 0.3810092564944706 0.4688618448033466 0.6391683906407226 1.0 0.6784832765556048 2 Q8N2W9 1 +PINIT domain [IPR023321] 0.3810092564944706 0.4688618448033466 0.6391683906407226 1.0 0.6784832765556048 2 Q8N2W9 1 +Ribosomal protein L18e/L15P [IPR021131] 0.4183981481805403 0.4557997594076142 0.6485339771501113 1.0 0.687905760830793 3 Q9P015 1 +Domain of unknown function DUF1605 [IPR011709] 0.3833063924444167 0.4542791627591362 0.6496279117320942 1.0 0.6885468408825851 13 Q9H6S0,Q9H2U1,Q7Z478,Q8IX18,O60231,Q14147,Q92620 7 +Helicase-associated domain [IPR007502] 0.3833063924444167 0.4542791627591362 0.6496279117320942 1.0 0.6885468408825851 13 Q9H6S0,Q9H2U1,Q7Z478,Q8IX18,O60231,Q14147,Q92620 7 +L27 domain, C-terminal [IPR014775] 0.4163679808840972 0.4481132745627714 0.6540714482342989 1.0 0.6925887852750344 3 Q5T2T1,O14936 2 +Aminotransferase, class I/classII [IPR004839] 0.4294258373205624 0.4284634655656341 0.6683137270179371 1.0 0.7070201256492881 7 O15269,O15270,Q6YP21,Q8TD30,O75600,P00505 6 +ELM2 domain [IPR000949] 0.4089008363201744 0.4202986106566814 0.6742673247254443 1.0 0.7122470839101295 3 Q9UKL0,Q13330 2 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.3624962675425472 0.3938652739171739 0.6936805097119514 1.0 0.7302856563696554 2 P22033 1 +C2 domain [IPR000008] 0.3272761521627199 0.3796467457745498 0.704207656099346 1.0 0.7408138132413838 19 O14795,P19174,Q96PU5,Q16512,P17252,Q9NZM3 6 +AAA+ ATPase domain [IPR003593] 0.2632476128175762 0.3715509341877533 0.7102272265152632 1.0 0.7457518432950486 56 Q99741,Q15645,P62191,P08183,P25205,Q9NUQ8,Q5T9A4,Q96TA2,O75027,O43933,P40938,Q9UG63,O76031,P28288,P62195,P06576,P55072,Q9H078,Q9NRK6,P35251,Q9NVI7,Q8WVB6 22 +GTP binding domain [IPR006073] 0.3642089801078913 0.3666322304713742 0.7138933634525717 1.0 0.748762875239405 13 P36915,Q969Y2,Q9H089,Q9Y295 4 +tRNA-binding domain [IPR002547] 0.3523439832785862 0.3552242580334737 0.7224215929667008 1.0 0.7574252482353073 2 Q12904 1 +Band 7 domain [IPR001107] 0.4019853971167966 0.3303053336201033 0.7411692632486075 1.0 0.7762133795675105 7 Q9UJZ1,Q14254 2 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.3445804717826141 0.3269805052477155 0.7436826300455626 1.0 0.778266085683842 2 Q9UBF2 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.3445804717826141 0.3269805052477155 0.7436826300455626 1.0 0.778266085683842 2 Q9UBF2 1 +Glycosyltransferase 2-like [IPR001173] 0.4196936647990626 0.3253667736929245 0.7449034993650276 1.0 0.7786746725060657 4 Q10472,Q9Y673 2 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.4141362126928005 0.3230948943660153 0.7466233767910204 1.0 0.7798928922811513 5 Q9ULE6 1 +Amine oxidase [IPR002937] 0.3802270011947337 0.3208665044172583 0.7483115584447362 1.0 0.7807865036739773 3 Q8NB78,P50336 2 +Pleckstrin homology domain [IPR001849] 0.2826070771474668 0.3046208125610156 0.7606549668142717 1.0 0.7927834092806767 30 O94887,Q6WCQ1,Q13464,Q01082,P19174,O60333,O75116,Q96AC1,P11274,P50570,Q92974,Q8IYI6,Q92888,Q96SU4,Q9Y5P4,Q9NZM3,Q9BXW6 17 +Histone deacetylase domain [IPR023801] 0.3724611708482556 0.2961649969772235 0.767104078690912 1.0 0.798321780746406 3 Q9UBN7,Q13547 2 +Bromo adjacent homology (BAH) domain [IPR001025] 0.4090230056767262 0.2938243159022851 0.768892153400851 1.0 0.7998866965667877 4 Q86U86,P26358,Q13330 3 +Heat shock chaperonin-binding [IPR006636] 0.4039386677837372 0.279363903387972 0.7799655696436736 1.0 0.8108067802689038 4 P31948 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.3966847113397936 0.2593924282682809 0.7953324712114644 1.0 0.824839208891702 4 P06576 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.3966847113397936 0.2593924282682809 0.7953324712114644 1.0 0.824839208891702 4 P06576 1 +MIF4G-like, type 3 [IPR003890] 0.3798155643825393 0.2591535024311488 0.7955168054472761 1.0 0.824839208891702 7 Q09161 1 +Helicase/UvrB, N-terminal [IPR006935] 0.3512544802867215 0.2341048517714214 0.8149035794155464 1.0 0.8418375941593581 3 P19447,Q9UPY3 2 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.3862930414991309 0.2321779202847012 0.8163998262803815 1.0 0.8430736825722149 4 Q96CB9 1 +Dehydrogenase, E1 component [IPR001017] 0.3120334428187452 0.2222669586479944 0.8241060719655227 1.0 0.8497945694437384 2 Q02218 1 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.3108390564347498 0.2188748701469657 0.8267475225651422 1.0 0.8521952293791663 2 O94973 1 +SWIRM domain [IPR007526] 0.3803406035255484 0.2173518110755292 0.8279341826384972 1.0 0.8531058079714625 4 Q92922,Q8TAQ2,Q8NB78 3 +Peptidase M16, middle/third domain [IPR032632] 0.309644670050752 0.2155161482590244 0.8293649233696088 1.0 0.8542642111118687 2 P14735 1 +Protein kinase, C-terminal [IPR017892] 0.3690960616933371 0.1981498476060318 0.8429278251947023 1.0 0.8650696724818305 5 P17252 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.333625124270655 0.1889275404272004 0.8501496081262756 1.0 0.8721629641353805 3 Q06210 1 +RNA polymerase Rpb2, domain 4 [IPR007646] 0.2956106300388088 0.1785854970676875 0.8582631830767837 1.0 0.8788839949017082 2 P30876 1 +RNA polymerase Rpb2, domain 5 [IPR007647] 0.2956106300388088 0.1785854970676875 0.8582631830767837 1.0 0.8788839949017082 2 P30876 1 +Disulphide isomerase [IPR005788] 0.3604303646144599 0.1779021798965875 0.8587997988469833 1.0 0.8791134767673087 5 Q15084,Q8NBS9,P30101,P13667 4 +Chromo/chromo shadow domain [IPR000953] 0.3213393782586415 0.1747259253879874 0.8612949956189395 1.0 0.8810264809731189 12 P83916,Q92993 2 +SH3 domain [IPR001452] 0.2558506176732474 0.159310984265779 0.8734238670897294 1.0 0.8927839164692619 34 Q9UKS6,Q03001,Q9UNF0,Q9UQB8,Q12959 5 +SGS domain [IPR007699] 0.2773962376828783 0.1377343796057309 0.8904503473421359 1.0 0.9091966704440756 2 Q9HB71 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.302367384270882 0.1353326685757362 0.8923488568758731 1.0 0.9108045480376744 13 P31483,Q9UHX1,Q01081,Q13310 4 +THIF-type NAD/FAD binding fold [IPR000594] 0.3197726592880621 0.122004512545887 0.9028954444766596 1.0 0.9199003568681068 8 Q13564,P22314,Q9UBT2,A0AVT1,Q8TBC4,O95352,Q9GZZ9 7 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.3296473401075854 0.1165551965154953 0.9072125436437486 1.0 0.9239641148696108 5 P62195,P43686,P62191,P17980 4 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9241588356917856 3 P30876,Q9H9Y6 2 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9241588356917856 3 P30876,Q9H9Y6 2 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9241588356917856 3 P30876,Q9H9Y6 2 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9241588356917856 3 P30876,Q9H9Y6 2 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9241588356917856 3 P30876,Q9H9Y6 2 +Longin domain [IPR010908] 0.289426523297481 0.1027457624493819 0.918164752629896 1.0 0.9314091053544528 3 O15498,P51809 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.289426523297481 0.1027457624493819 0.918164752629896 1.0 0.9314091053544528 3 O15498,P51809 2 +Phosphoribosyltransferase domain [IPR000836] 0.3130980861243992 0.0982630075748399 0.9217234516618218 1.0 0.9336723332822128 7 Q9NRG1,Q06203,P07741,P00492,O60256,P11908 6 +Zinc finger, UBR-type [IPR003126] 0.2825567502986785 0.0928004510525883 0.926062092670466 1.0 0.9373921074782372 3 O95071,Q5T4S7 2 +Phox homology [IPR001683] 0.2957070415122567 0.0923459786928915 0.9264231586952638 1.0 0.9374202681330134 11 Q9Y5X1,Q9Y5X3,Q9UNH7,O60749,Q13596,Q15036 6 +AGC-kinase, C-terminal [IPR000961] 0.3020430829918724 0.0917018367914228 0.9269349379946096 1.0 0.9376008560154034 9 P17252,O75116,Q13464,Q16512 4 +Mu homology domain [IPR028565] 0.2972811472960799 0.071527965266849 0.9429775684893288 1.0 0.9514332496988814 4 Q96CW1,Q9BXS5,P48444 3 +WW domain [IPR001202] 0.2743032813481815 0.0630864301579777 0.9496976799394534 1.0 0.9578700515129732 13 Q96PU5,Q13576 2 +Cullin, N-terminal [IPR001373] 0.2870648491217781 0.0586444278257286 0.9532353232662374 1.0 0.9610935356085756 7 Q93034,Q13618 2 +Zinc finger, UBP-type [IPR001607] 0.2829399462204885 0.0574735060578983 0.954168010316936 1.0 0.9613447754375146 4 Q8TEY7,Q9UBN7,Q53GS9 3 +CAP Gly-rich domain [IPR000938] 0.2601452432366565 0.0407587355826319 0.9674882362373955 1.0 0.9737189297086918 4 P30622 1 +Rhodanese-like domain [IPR001763] 0.2669656203288587 0.0371344284003819 0.9703778210566514 1.0 0.9762778292676538 6 P40818,Q99956,P25325,Q16762,Q8NCN5 5 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.2494771437107793 0.0350026098012872 0.9720776598294552 1.0 0.9772889410651384 4 Q6PCE3,Q96G03,O95394 3 +Chromo domain [IPR023780] 0.2536611676362147 0.0214888492480513 0.9828556984215708 1.0 0.9860103707774176 9 P83916,Q12873,Q13185 3 +AP complex, mu/sigma subunit [IPR022775] 0.2222016261865386 0.0188510657797162 0.9849599164456964 1.0 0.9876809129469936 5 P61923 1 +SPRY domain [IPR003877] 0.244404075065084 0.0099401735880877 0.9920690195687109 1.0 0.993481720201774 13 Q9BUJ2,Q9C037,P14373,O15344,Q00839 5 +B30.2/SPRY domain [IPR001870] 0.244404075065084 0.0099401735880877 0.9920690195687109 1.0 0.993481720201774 13 Q9BUJ2,Q9C037,P14373,O15344,Q00839 5 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..255b130dc6d32206b5703526638d31338bfcb2f1 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal [IPR007177]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AF-9, ANC1 homology domain [IPR040930]", "AF4/FMR2, C-terminal homology domain [IPR043640]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Argonaute hook domain [IPR019486]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 16 domain [IPR013923]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BACH, basic leucine zipper (bZIP) domain [IPR043321]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic leucine zipper domain, Maf-type [IPR004826]", "Basic-leucine zipper domain [IPR004827]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBP/p300-type histone acetyltransferase domain [IPR031162]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLIP1, zinc knuckle [IPR032108]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CREB-binding protein/p300, atypical RING domain [IPR010303]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbohydrate kinase, FGGY, N-terminal [IPR018484]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, KIX domain [IPR003101]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein Mlh1, C-terminal [IPR032189]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA polymerase, Y-family, little finger domain [IPR017961]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA repair protein Rev1, C-terminal [IPR031991]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DNAJC17, RNA recognition motif [IPR034254]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1907 [IPR015021]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4485 [IPR027831]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase SH3RF1, second SH3 domain [IPR035795]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain [IPR033928]", "Eps8, SH3 domain [IPR035462]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM21/CAPZIP domain [IPR029341]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G protein-regulated inducer of neurite outgrowth, C-terminal [IPR032745]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HARP domain [IPR010003]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HMG box transcription factor BBX, domain of unknown function DUF2028 [IPR019102]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "INTS6/SAGE1/DDX26B/CT45, C-terminal [IPR029307]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Initiation factor eIF2 gamma, C-terminal [IPR015256]", "Initiation factor eIF2 gamma, GTP-binding domain [IPR044128]", "Initiation factor eIF2 gamma, domain 2 [IPR044127]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Interleukin-1 receptor-associated kinase 1, death domain [IPR035533]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "LACTB2, winged helix domain [IPR041516]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper with capping helix domain [IPR040661]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAD homology 1, Dwarfin-type [IPR003619]", "MAD homology, MH1 [IPR013019]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR6, PH-GRAM domain [IPR035998]", "MUN domain [IPR010439]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Mammalian uncoordinated homology 13, domain 2 [IPR014772]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Microspherule protein, N-terminal domain [IPR025999]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Mnd1, HTH domain [IPR040453]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Munc13 homology 1 [IPR014770]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear receptor coactivator, CREB-bp-like, interlocking [IPR014744]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome biogenesis factor 1, N-terminal, alpha/beta [IPR015343]", "Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold [IPR015342]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein NPAT, C-terminal domain [IPR031442]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein Smaug, SAM domain [IPR037634]", "Protein Unc-13, C2B domain [IPR037302]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Putative zinc-finger domain [IPR019607]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "Quinolinate phosphoribosyl transferase, C-terminal [IPR002638]", "Quinolinate phosphoribosyl transferase, N-terminal [IPR022412]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad4 beta-hairpin domain 1 [IPR018326]", "Rad4 beta-hairpin domain 2 [IPR018327]", "Rad4 beta-hairpin domain 3 [IPR018328]", "Rad4/PNGase transglutaminase-like fold [IPR018325]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Rapamycin-insensitive companion of mTOR, N-terminal domain [IPR028267]", "Rapamycin-insensitive companion of mTOR, domain 4 [IPR029453]", "Rapamycin-insensitive companion of mTOR, domain 5 [IPR029452]", "Rapamycin-insensitive companion of mTOR, middle domain [IPR029451]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3RF1/SH3RF3, fourth SH3 domain [IPR035816]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKI/SNO/DAC domain [IPR003380]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAD domain, Dwarfin-type [IPR001132]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TNRC6, PABC binding domain [IPR032226]", "TNRC6B, RNA recognition motif [IPR034925]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Tensin/EPS8 phosphotyrosine-binding domain [IPR013625]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UBXN6, PUB domain [IPR042774]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific peptidase 1 [IPR033815]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "UmuC domain [IPR001126]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain KLRAQ/TTKRSYEDQ, C-terminal [IPR019348]", "Uncharacterised domain KLRAQ/TTKRSYEDQ, N-terminal [IPR019343]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat protein mio, zinc-ribbon like domain [IPR031488]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "ZZZ3, zinc finger, ZZ-type [IPR041981]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TAZ-type [IPR000197]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "APIP", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "ARSA", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS3", "BCKDHB", "BCL10", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C11orf54", "C1orf35", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CBL", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD47", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COASY", "COG2", "COIL", "COL4A3BP", "COMMD10", "COMMD4", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRABP2", "CREBBP", "CRKL", "CROT", "CRYZ", "CRYZL1", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWC27", "CWF19L1", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DACH1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCP1B", "DCP2", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D5", "DDB1", "DDHD2", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM208A", "FAM208B", "FAM49B", "FANCA", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GALK1", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS6", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8C", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METAP1", "METAP2", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGME1", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MINDY3", "MIOS", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R21", "PPP1R8", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAI1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REL", "RELA", "REPS1", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RTFDC1", "RTKN", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STOML2", "STRBP", "STRIP1", "STRN", "STRN3", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6", "TAGLN2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSR1", "TSR3", "TST", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC2A", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRNIP1", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF2", "ABCF3", "ABHD10", "ACTN1", "AIMP1", "ALG5", "ANKFY1", "AP1M1", "AP2A2", "AP2M1", "APIP", "APRT", "ARCN1", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARIH2", "ATAD3A", "ATAD3B", "ATG7", "ATP11C", "ATP13A1", "ATP5B", "BAIAP2", "BCR", "BRD4", "BSG", "CACYBP", "CALU", "CAMK2G", "CARS2", "CASK", "CBX1", "CBX3", "CDC5L", "CDC6", "CDK2", "CDK6", "CELF2", "CHD3", "CHEK1", "CHTF18", "CHUK", "CIAPIN1", "CKB", "CLASP2", "CLCN3", "CLIP1", "CLPB", "CLPX", "CNDP2", "CNNM3", "COL4A3BP", "COPG2", "COPS3", "COPS6", "COPS7A", "COPZ1", "CUL3", "CUL4B", "CUL5", "DCUN1D5", "DDX50", "DHX16", "DHX29", "DHX34", "DHX36", "DHX38", "DHX40", "DICER1", "DLG1", "DNA2", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC17", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DRG1", "DST", "DTNA", "DUSP9", "ECT2", "EIF2B3", "EIF3A", "EIF3E", "EIF3F", "EIF3M", "EIF5", "ERCC3", "EXOC8", "EXOSC1", "EZR", "FARP2", "FARSA", "FASN", "FBXO22", "FERMT2", "FLOT2", "FUBP1", "GALNT1", "GARS", "GATAD2B", "GCAT", "GFPT1", "GMPPB", "GNL1", "GOT2", "GPT2", "GTF2B", "GTPBP3", "HDAC1", "HDAC6", "HIF1AN", "HK2", "HMGB1", "HMMR", "HNRNPF", "HNRNPH1", "HNRNPLL", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "IDE", "IQGAP2", "ITSN2", "JMJD6", "KAT5", "KCTD10", "KDM1B", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "KTN1", "KYAT3", "LENG8", "LIG1", "LMNB1", "LMNB2", "LPCAT1", "LSG1", "MAEA", "MAP2K2", "MARK2", "MCM3", "MCM3AP", "MCM5", "MCM6", "METAP1", "MFN2", "MID1", "MIPEP", "MORF4L1", "MPP7", "MPRIP", "MPST", "MRPL15", "MRPL43", "MSH3", "MSN", "MTA1", "MTOR", "MTX1", "MUT", "MYH10", "MYH9", "MYO1D", "MYO5A", "NAA10", "NAE1", "NCBP1", "NDUFA2", "NEDD4L", "NEFM", "NF2", "NONO", "NPC1", "NSUN4", "NUCB2", "OCRL", "OGDH", "OPA1", "OSBPL1A", "OSBPL9", "P3H1", "P4HA1", "PABPC4", "PACSIN2", "PACSIN3", "PAK2", "PALD1", "PAPSS1", "PARP1", "PBRM1", "PCBP2", "PCID2", "PDIA3", "PDIA4", "PDIA6", "PDPR", "PEX1", "PGM2", "PGM2L1", "PGM3", "PI4KB", "PIAS4", "PKN1", "PLCG1", "PLS1", "POLA1", "POLD1", "POLR1B", "POLR2B", "PPAT", "PPOX", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRPS2", "PRPSAP1", "PRPSAP2", "PRTFDC1", "PSMC1", "PSMC3", "PSMC4", "PSMC5", "PSMD11", "PSMD13", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSPC1", "PUF60", "QARS", "QKI", "RABGAP1", "RABGEF1", "RARS2", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RFC1", "RFC3", "RIOX2", "ROCK1", "ROCK2", "RPL26", "SARS", "SCYL2", "SEC23A", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SMARCA1", "SMARCC1", "SMARCC2", "SMG5", "SNU13", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQOR", "SRBD1", "SRM", "SRPK2", "STAG1", "STAMBP", "STAT3", "STIP1", "STK4", "STOML2", "STX4", "SUCLG1", "TARS2", "TARSL2", "TBC1D9B", "TDRKH", "TFAM", "TFIP11", "TGFBRAP1", "TIA1", "TIMM13", "TMEM97", "TRIM27", "TRIM4", "TRIP13", "TRRAP", "TSR1", "TST", "TUBB4A", "TUBGCP2", "TXNDC5", "TXNL1", "U2AF1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBR4", "UBR5", "UNC13B", "UQCRC2", "USP33", "USP39", "USP48", "USP8", "VAMP7", "VCP", "VIM", "VPS51", "WARS", "YKT6", "YME1L1", "YTHDC2"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0732627f4fb3fda76d5d14c0285b15e45183c162 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Ezrin/radixin/moesin-like [IPR000798]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..961b61b152dfa0b5a40007dcefa71d93d7499a3e --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31586bbcbd9275a7dafb948def57aa35b15506b99d72210031a504ed3df6a6c3 +size 188733 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..26b6572ac18400b59a20f4f817ca3029d31541d5 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ezrin/radixin/moesin-like [IPR000798]", "1": "Sec1-like protein [IPR001619]", "2": "Kinesin-like protein [IPR027640]", "3": "ThiF/MoeB/HesA family [IPR045886]", "4": "Actin family [IPR004000]", "5": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ba6839a2f4382d0f5c3c28a8093a166e327a47da --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8788b7ecb81c453aec35fef969bccd859507f59cdff9a8a698ad799b93fd261 +size 133892 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..94fceb54a8e1dfaeb0552cd6ac5833fd77740f14 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ea843a9dec3237b3b782c0332ed28efa332289670714c3a92f87ea95fbe4e2e +size 133508 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3069e34bc1f9594d3712c200b24aab96f00d1725 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be3701b9d2b5130add8c5cf213dd28e95966919c0dbdd70f1587eaa57d2e27d4 +size 136157 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2c331b1dbe2236c393448352557ac664d92f8360 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3dea05ff9de07f7e5a57e3e5fd5c5d247844c97d113a3f2f0febc4912d7c21e7 +size 144239 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..206cfe313dd726f3837d1b1c143cabc824e42bb3 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bf5e18a9622414849634e356561c49bc209d9bb9a923995156fc9fffa9bc324 +size 138686 diff --git a/interpro_family/basic/plot_5.png b/interpro_family/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..06de7b41b4b23cdf85d6c013000aca0c5bce1dbc --- /dev/null +++ b/interpro_family/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e70f161e959e49c69842eb24bd3d198df6c9d170fb302f0f31c26ac4188c080 +size 151036 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..878d994e768de40b631df41c87ebb07af7af67e5 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9195aaa1c59c105e5ae055b2d2b560bf2f9326bb27ef7aa8cbeb516925626136 +size 815859 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f16e039d3d7a0b4362cff156f6f5d5de81272a1e --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +P-type ATPase [IPR001757] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.0983610682747182 0.0892170338783466 +Ezrin/radixin/moesin-like [IPR000798] 5 9 2.08048619746713 0.0374809603350807 3.808252427184466 7.223300970873787 -0.3634386129543082 0.4956493480808617 1.9816218361052296 1.2651569520419308 0.896156524909112 0.2987266510010755 1.0 1.0 0.003355333516566 0.0002504856541451 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f3e1f11012848590b9ff7cbeabef286eaee517f7 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 2562, + "title": "Average number of proteins per term", + "value": 1.274785323965652 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9a7fb02e883c0246c7d8d5e38d00d54eda838547 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eadb667a91cd93426c5ba69d0788e2e3e483fa77 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,108 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9991042102120036 3.4370712015943616 0.0005880409986982 0.7784272214699249 0.0033004582288701 2 O60830 1 +CD36 family [IPR002159] 0.9919378919080322 3.4066019997520116 0.0006577696747971 0.8146965242899267 0.0033839476040768 2 Q14108 1 +Haem oxygenase [IPR002051] 0.9868617497760512 3.3849517614343614 0.0007119076424908 0.838710906947411 0.0035347042249255 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9868617497760512 3.3849517614343614 0.0007119076424908 0.838710906947411 0.0035347042249255 2 P30519 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9773066587040882 3.3440445191519332 0.0008256648665974 0.87951465548156 0.0038114475463469 2 Q9H2D1 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.9590922663481624 3.265502316427795 0.0010927011175554 0.9392525933657696 0.0043616719915569 2 Q9Y5L4 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9540161242161782 3.243480539303196 0.0011807887670671 0.9515376600334916 0.0045559952126899 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9540161242161782 3.243480539303196 0.0011807887670671 0.9515376600334916 0.0045559952126899 2 Q93050 1 +Tropomyosin [IPR000533] 0.940579277396231 3.1849045129517033 0.0014480177877485 0.9755838409982572 0.0052031158095535 2 P67936 1 +Sec13/Seh1 family [IPR037363] 0.9277396237682856 3.1285441447170825 0.0017567461989469 0.9889435550232994 0.0059220838969764 2 P55735 1 +Defective-in-cullin neddylation protein [IPR014764] 0.9199761122723128 3.094280050594453 0.0019729116044051 0.9936518524775142 0.0063579868308 2 Q9BTE7 1 +Peptidase M24, methionine aminopeptidase [IPR001714] 0.9119140041803432 3.0585486985913586 0.0022241192677991 0.99666918981777 0.0069152187617266 2 P53582 1 +Porin, eukaryotic type [IPR001925] 0.9810155804011452 2.960548465354143 0.0030709180026029 0.9996216902412536 0.008551839046379 3 P21796 1 +Translation initiation factor IF2/IF5 [IPR045196] 0.8874290833084528 2.9490874024381863 0.0031871382626604 0.9997193741159645 0.0087424499239145 2 P55010 1 +Nucleobindin [IPR040250] 0.8781725888324753 2.9073316237787163 0.0036452652701879 0.9999135749485766 0.0095492531924555 2 P80303 1 +SAC3/GANP/THP3 [IPR045107] 0.8727978501044986 2.882991218214606 0.0039391842249867 0.99995941531737 0.0100319979964373 2 Q96PV6 1 +Prefoldin alpha-like [IPR004127] 0.8596595998805637 2.8231963586840285 0.004754744083756 0.9999950231171416 0.0114167332170413 2 P61758 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.8572708271125731 2.812279206663791 0.0049191782713213 0.9999967408196012 0.0116585890204675 2 Q9P0I2 1 +DNA helicase, ATP-dependent, RecQ type [IPR004589] 0.8530904747685781 2.7931404690194945 0.0052199019281142 0.9999984975516836 0.0121026142441889 2 P46063 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8489101224246074 2.7739587218777935 0.0055378704400237 0.9999993376392112 0.012634037459787 2 Q5T9A4 1 +HnRNP R/Q splicing factor [IPR006535] 0.8268139743206964 2.6718510712432044 0.0075434119087445 0.9999999962423904 0.0159194574219138 2 O43390 1 +Ribosomal protein L15 [IPR030878] 0.8124813377127542 2.6049689807612997 0.0091882578012678 0.9999999999463816 0.0185942468300539 2 Q9P015 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.8091967751567671 2.589569425815714 0.0096096043503424 0.999999999981968 0.0192287416664145 2 Q9H267 1 +Dedicator of cytokinesis [IPR026791] 0.8077037921767698 2.5825606859809525 0.0098070112835806 0.9999999999891797 0.019515669996297 2 Q14185 1 +Eukaryotic porin/Tom40 [IPR027246] 0.9657849396634366 2.550675661934154 0.0107514328128119 0.9999999999990612 0.0208833744248857 4 P21796 1 +ATP:guanido phosphotransferase [IPR000749] 0.8008360704688 2.550248434660536 0.0107646180325795 0.9999999999990928 0.0208931449995975 2 P12277 1 +Dynamin [IPR022812] 0.8808243727598546 2.5409961157690777 0.0110537147517302 0.999999999999571 0.0212609738693189 3 O00429,O60313 2 +F-actin-capping protein subunit alpha [IPR002189] 0.7987458942968058 2.54039076138562 0.0110728677869571 0.9999999999995918 0.021281835911616 2 P47755 1 +Ancient conserved domain protein family [IPR045095] 0.7969543147208153 2.5319325898513534 0.0113435796761196 0.9999999999997976 0.0216882471121033 2 Q8NE01 1 +Ras GTPase GNL1-like [IPR043358] 0.7826216781128664 2.463976706836839 0.0137405040702864 0.9999999999999996 0.02498473297065 2 Q9H089 1 +FAM98 [IPR018797] 0.7787399223648851 2.44548309305036 0.0144658230818117 1.0 0.0259533884703093 2 Q52LJ0 1 +Nonaspanin (TM9SF) [IPR004240] 0.8549859589031956 2.429439814041052 0.015122175427233 1.0 0.026830341720617 3 Q9HD45 1 +Isocitrate dehydrogenase NAD-dependent [IPR004434] 0.7715736040609122 2.4112415413138195 0.0158983156064058 1.0 0.0278601125742899 2 P50213 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.8490033872792679 2.4034122290019253 0.0162428656989819 1.0 0.0283282654328057 3 Q9BZJ0 1 +Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909] 0.7694834278888979 2.401230124585034 0.0163400569886238 1.0 0.0284203842531257 2 Q9HA77 1 +Cysteine-tRNA ligase [IPR015803] 0.7694834278888979 2.401230124585034 0.0163400569886238 1.0 0.0284203842531257 2 Q9HA77 1 +Ezrin/radixin/moesin [IPR011174] 0.922318494173887 2.3782454975691505 0.0173952403323263 1.0 0.0297706117110354 4 P35241,P26038,P15311 3 +Sorting nexin-5/6/32 [IPR014637] 0.7417139444610089 2.2671839670499248 0.0233789898374916 1.0 0.0376473739557847 2 Q9UNH7 1 +Transcriptional repressor p66 [IPR040386] 0.7414153478650357 2.265732175195685 0.0234677862944967 1.0 0.0377429180706218 2 Q8WXI9 1 +Flotillin family [IPR027705] 0.7387279785010424 2.252656121415543 0.0242808395933029 1.0 0.0388069314023968 2 Q14254 1 +P-type ATPase [IPR001757] 0.8728153156317219 2.240228261847668 0.0250761077794481 1.0 0.039635085510057 5 Q8NB49,Q9HD20 2 +Dynein light chain, type 1/2 [IPR001372] 0.7351448193490407 2.2351936362688023 0.0254046390983895 1.0 0.0400287117897133 2 Q96FJ2 1 +Mitofusin family [IPR027094] 0.7282770976410838 2.2016355804361742 0.0276910605059335 1.0 0.0427729138556627 2 O95140 1 +Dynein 1 light intermediate chain [IPR008467] 0.7229023589131057 2.175292235263721 0.0296082240295514 1.0 0.0450720558310818 2 O43237 1 +Dynein family light intermediate chain [IPR022780] 0.7229023589131057 2.175292235263721 0.0296082240295514 1.0 0.0450720558310818 2 O43237 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.7199163929531207 2.1606266676822905 0.0307241897179815 1.0 0.0464397487064711 2 Q13464 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.7196177963571204 2.1591589218092673 0.0308378397255753 1.0 0.0465514053284614 2 O43819 1 +Copper chaperone SCO1/SenC [IPR003782] 0.7196177963571204 2.1591589218092673 0.0308378397255753 1.0 0.0465514053284614 2 O43819 1 +Luc7-related [IPR004882] 0.7187220065690967 2.154754389313902 0.0311810591606598 1.0 0.0468538847915604 2 Q9Y383 1 +Vinculin/alpha-catenin [IPR006077] 0.7181248133771263 2.1518169561108533 0.0314117738369401 1.0 0.0471452633686237 2 P35221 1 +SCAMP [IPR007273] 0.7900327235993744 2.142904464143293 0.0321207704524055 1.0 0.0479274704846708 3 O15127 1 +Arginine-tRNA ligase [IPR001278] 0.7133472678411479 2.1282865275692933 0.0333133344347134 1.0 0.0493630785550814 2 Q5T160 1 +Ezrin/radixin/moesin-like [IPR000798] 0.75591931784849 2.08048619746713 0.0374809603350807 1.0 0.0543221060285935 9 P35241,O94887,P35240,P15311,P26038 5 +E3 ubiquitin ligase RBR family [IPR031127] 0.6864735742012482 1.9949202633116323 0.046051577102222 1.0 0.0640521935591166 2 O95376 1 +Gamma-tubulin complex component protein [IPR007259] 0.6834876082412598 1.9799985664495872 0.0477036897659781 1.0 0.0657079855808795 2 Q9BSJ2 1 +Prolyl 4-hydroxylase [IPR045054] 0.6595998805613615 1.859916271146521 0.0628973729080413 1.0 0.082090203459196 2 P13674 1 +Ribosomal protein L37/S30 [IPR010793] 0.6440728575694225 1.7812211580009856 0.0748763285049465 1.0 0.0943862060040891 2 Q9NP92 1 +Hexokinase [IPR001312] 0.6419826813974348 1.7705913401384186 0.0766286830585714 1.0 0.096142353572997 2 P52789 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7079646360248818 1.7690404191387312 0.0768871296243882 1.0 0.09637222411824 3 P55209 1 +Protein transport protein Sec23 [IPR037364] 0.6354135562854597 1.7371298626728766 0.0823642513512545 1.0 0.1021875118459633 2 Q15436 1 +DNA-directed DNA polymerase, family B [IPR006172] 0.6965352449223349 1.7160461099187865 0.0861536033763248 1.0 0.1060670503844998 3 P28340,P09884 2 +DNA2/NAM7-like helicase [IPR045055] 0.7607300852668801 1.7093167971181469 0.0873922835578762 1.0 0.1072827170461326 4 P51530 1 +DNA ligase, ATP-dependent [IPR000977] 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.1173817724757275 2 P18858 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.6717443249701237 1.6004578164034278 0.109497057836061 1.0 0.1288023242313996 3 Q9Y5Y2,Q8TB37 2 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.6717443249701237 1.6004578164034278 0.109497057836061 1.0 0.1288023242313996 3 Q9Y5Y2,Q8TB37 2 +Mini-chromosome maintenance protein [IPR031327] 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.1358257175729937 6 Q14566,P33992,P25205 3 +Type II pantothenate kinase [IPR004567] 0.5989847715736071 1.550257245141753 0.1210797848478559 1.0 0.1398586153202015 2 Q9H999 1 +HnRNP-L/PTB [IPR006536] 0.6490535903532592 1.494017691314917 0.1351709953176108 1.0 0.152997096264033 3 Q8WVV9 1 +Peptidase M20 [IPR002933] 0.5780830098536844 1.4422452033756603 0.1492332125633679 1.0 0.165656625037846 2 Q96KP4 1 +Septin [IPR016491] 0.6616603686413556 1.379138418435791 0.1678520805765972 1.0 0.1820920998459651 6 Q9P0V9,Q16181,Q15019,Q14141 4 +DNA mismatch repair MutS family [IPR045076] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.1958829073475482 3 P20585 1 +Phosphatidylinositol kinase [IPR015433] 0.6061238723357918 1.2916308520025366 0.1964850144149466 1.0 0.2077567506938065 3 Q9UBF8 1 +Peptidase M3A/M3B [IPR045090] 0.6018041862125638 1.2712422266389316 0.2036424884558374 1.0 0.2146162301208784 3 Q99797 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.5374738727978565 1.2317022921860452 0.2180603132764065 1.0 0.2292451877776584 2 P54709 1 +C-terminal binding protein [IPR043322] 0.508211406389974 1.0804745715524722 0.2799309043003442 1.0 0.2924889791262161 2 P56545 1 +Cullin [IPR045093] 0.599002594046584 1.0529075163350743 0.2923833809082672 1.0 0.3052511091633988 5 Q13620,Q93034,Q13618 3 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.5019408778739995 1.0482472941721774 0.2945246858315553 1.0 0.3072362561483895 2 O60884 1 +Endoplasmic reticulum oxidoreductin 1 [IPR007266] 0.5001492982979979 1.0390559652971247 0.298778708839333 1.0 0.3115470297299028 2 Q86YB8 1 +Protein arginine N-methyltransferase [IPR025799] 0.5977442159675259 1.0071044979884958 0.3138845599132134 1.0 0.3268992855681515 4 Q99873 1 +Tubulin [IPR000217] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.3473948306539992 7 P04350 1 +Mitochondrial carrier protein [IPR002067] 0.5129180318316691 0.9446179936447202 0.3448539373264563 1.0 0.3579885686508837 10 P53007,P12235 2 +Transcription factor STAT [IPR001217] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.3640026918746749 2 P40763 1 +Glutathione Transferase family [IPR040079] 0.5101628598500059 0.93073616654614 0.3519900565764224 1.0 0.3648052285391563 10 Q9H7Z7 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.4640191101821473 0.8559208318647358 0.3920415713255401 1.0 0.4051676102202637 2 P10644 1 +Adenylyl-sulfate kinase [IPR002891] 0.4619289340101558 0.8454949672520098 0.3978345414302171 1.0 0.4106575725802644 2 O43252 1 +Cohesin subunit Scc3/SA [IPR039662] 0.4487906837862043 0.7805256784330128 0.4350815189988044 1.0 0.4485629181790491 2 Q8WVM7 1 +Fyv10 family [IPR045098] 0.4422215586742291 0.7484506643710152 0.4541883726428164 1.0 0.4675092851389697 2 Q7L5Y9 1 +Sec1-like protein [IPR001619] 0.4884593436326128 0.6681918984105589 0.5040111062544608 1.0 0.5179608721315397 7 Q96AX1,Q9H267,O00186,Q8WVM8,Q9NRW7 5 +Ribosomal protein S17/S11 [IPR000266] 0.4001194386383981 0.5516131780438508 0.5812134057684755 1.0 0.5953893424945359 2 Q9Y2R5 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.4396654719235201 0.539244153517806 0.5897183977207627 1.0 0.603619071098919 3 Q14558,O60256 2 +Kinesin-like protein [IPR027640] 0.4265683800642435 0.5287060079136919 0.5970094088324478 1.0 0.610837901529046 10 Q9Y496,P33176,Q99661,O00139,O95235 5 +Initiation factor 2B-related [IPR000649] 0.472064535404854 0.5007107338860595 0.6165747168894946 1.0 0.6298502490713258 4 Q9BV20,P49770,Q14232 3 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.3845924156464562 0.4839936207339278 0.628390396464362 1.0 0.6411534033220612 2 Q2NL82 1 +Ribosomal protein S11 [IPR001971] 0.3529411764705867 0.3574447859082388 0.7207588539190626 1.0 0.7313204688081736 2 P82912 1 +Coatomer gamma subunit [IPR017106] 0.3445804717826141 0.3269805052477155 0.7436826300455626 1.0 0.7539829434810967 2 Q9UBF2 1 +Histone deacetylase family [IPR000286] 0.3724611708482556 0.2961649969772235 0.767104078690912 1.0 0.7764996640087383 3 Q9UBN7,Q13547 2 +Protein disulphide isomerase [IPR005792] 0.3602150537634339 0.25933331013558 0.7953780805181421 1.0 0.8038495630325365 3 P13667,P30101 2 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.3862930414991309 0.2321779202847012 0.8163998262803815 1.0 0.8244447595310751 4 Q96CB9 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.3108390564347498 0.2188748701469657 0.8267475225651422 1.0 0.8345654660409355 2 O94973 1 +Molecular chaperone regulator BAG [IPR039773] 0.2959092266348068 0.1793221223207214 0.8576847772879621 1.0 0.8651135430754956 2 O95429 1 +Ribosomal protein L3 [IPR000597] 0.2911316810988251 0.1677947493100215 0.86674475337795 1.0 0.8735641456153846 2 P39023 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.2720214989549012 0.1272120600833973 0.8987725603663723 1.0 0.9044207775564204 2 Q13868 1 +ThiF/MoeB/HesA family [IPR045886] 0.3197726592880621 0.122004512545887 0.9028954444766596 1.0 0.9082128499211628 8 Q13564,P22314,Q9UBT2,A0AVT1,Q8TBC4,O95352,Q9GZZ9 7 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.9149770139616892 3 P30876,Q9H9Y6 2 +Actin family [IPR004000] 0.318983557548591 0.1006053777387293 0.9198637275514588 1.0 0.9241924980340538 6 O96019,P61160,P61163,P61158,Q9GZN1 5 +Syntaxin [IPR045242] 0.3065453641451812 0.0822168748957812 0.9344742546484772 1.0 0.9370344580858704 4 Q12846 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.2620400837571012 0.0317557908558672 0.9746668026253338 1.0 0.9754282610648848 8 P49368,P50991,Q99832,P17987,P50990,P40227,P78371 7 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c686a5140ac01170e73a537fb771ea198258ff47 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3 [IPR022968]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AF4/FMR2 family [IPR007797]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abr/Bcr [IPR037769]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic fibroblast growth factor intracellular-binding protein [IPR008614]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin filament-associated protein 1 [IPR029907]", "Actin-filament associated protein [IPR030113]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Activating signal cointegrator 1-like [IPR039128]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-1,2-mannosyltransferase ALG9-like [IPR039484]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 16 [IPR045160]", "Autophagy-related protein 5 [IPR007239]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1/2/3 [IPR045068]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-ketoacyl synthase [IPR000794]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "C2H2-type Zinc finger protein, YY1-like [IPR017114]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Carnosine N-methyltransferase [IPR012901]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Caspase-6 [IPR037554]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad4 [IPR004583]", "DNA repair protein Rad4, subgroup [IPR018026]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein Rev1 [IPR012112]", "DNA repair protein XPF [IPR006167]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deltex family [IPR039398]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Distrobrevin [IPR017432]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dwarfin [IPR013790]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 SUMO-protein ligase PIAS4 [IPR027224]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ephrin receptor type-A /type-B [IPR016257]", "Epidermal growth factor receptor kinase substrate 8 [IPR030222]", "Epidermal growth factor receptor kinase substrate 8-like [IPR039801]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Erg28 [IPR005352]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Eukaryotic translation initiation factor SUI1 [IPR005874]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Family of unknown function DUF5525 [IPR037656]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flavinator of succinate dehydrogenase [IPR005631]", "Flotillin family [IPR027705]", "Folylpolyglutamate synthase, eukaryota [IPR023600]", "Folylpolyglutamate synthetase [IPR001645]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "Fyv7/TAP26 [IPR013730]", "G protein-regulated inducer of neurite outgrowth [IPR026646]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GPI mannosyltransferase [IPR005599]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-binding protein, beta subunit [IPR016346]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase KAT5/Tip60 [IPR037995]", "Histone acetyltransferase Rtt109/CBP [IPR013178]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone chaperone ASF1-like [IPR006818]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Homeobox protein Hox-A10/abdominal-B-like [IPR046333]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Interleukin-1 receptor-associated kinase 1 [IPR035536]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain-containing protein 1 [IPR028734]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Leo1-like protein [IPR007149]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper protein 1 [IPR026734]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MICRORCHIDIA ATPase family [IPR045261]", "MIOS/Sea4 [IPR037593]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Meiotic nuclear division protein 1 [IPR005647]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthioribulose-1-phosphate dehydratase [IPR017714]", "Methylthioribulose-1-phosphate dehydratase, eukaryotes [IPR027514]", "Methylthiotransferase [IPR005839]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microspherule protein 1 [IPR037912]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial mRNA pseudouridine synthase Trub2 [IPR039048]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [IPR033197]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyltransferase II [IPR007754]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NURS complex subunit red1 [IPR039278]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nicotinate-nucleotide pyrophosphorylase [IPR004393]", "Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD [IPR027277]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor of activated T cells (NFAT) [IPR008366]", "Nuclear factor of activated T-cells 5 [IPR015646]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "OTU domain-containing protein 5 [IPR031084]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PNN-interacting serine/arginine-rich protein [IPR031937]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome biogenesis factor 1 [IPR025653]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatase and actin regulator 4 [IPR029984]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotriesterase [IPR001559]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pianissimo family [IPR028268]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1 [IPR028608]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline racemase family [IPR008794]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FRG1 [IPR010414]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Unc-13 [IPR027080]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4507 [IPR027844]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 1 regulatory subunit 21 [IPR040024]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Quinone oxidoreductase-like protein 1 [IPR042633]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase I specific transcription initiation factor RRN3 [IPR007991]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab27a/b [IPR041837]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Raftlin family [IPR028169]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Rhotekin [IPR030471]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27 [IPR001684]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Ribosome-releasing factor 2, mitochondrial [IPR030851]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [IPR030101]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "SecY/SEC61-alpha family [IPR002208]", "Sedoheptulokinase [IPR042027]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase assembly factor 2, mitochondrial [IPR028882]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Sulphide quinone-reductase [IPR015904]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "Tastin [IPR026133]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor Spt20 [IPR021950]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor NocA-like [IPR022129]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trinucleotide repeat-containing gene 6B protein [IPR033500]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tumour suppressing sub-chromosomal transferable candidate 4 [IPR029338]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterized protein C11orf98 [IPR037691]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat domain phosphoinositide-interacting protein 4 [IPR032910]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR44/Dgr2 [IPR040324]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "ZZ-type zinc finger-containing protein 3 [IPR037830]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABHD12", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFF4", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APIP", "APLP2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "AS3MT", "ASAH1", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD31", "BYSL", "C11orf98", "C12orf57", "C15orf39", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD5", "C5orf15", "C5orf24", "C7orf26", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CECR2", "CELF2", "CENPB", "CENPF", "CENPI", "CENPU", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHERP", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG2", "COG7", "COIL", "COLGALT1", "COMMD10", "COMMD4", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRNKL1", "CROT", "CRTAP", "CRYZL1", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERG28", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIBP", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTB", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS2", "INTS3", "INTS5", "INTS7", "INTS8", "INTS9", "IPO4", "IPO5", "IRAK1", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JPT2", "JUP", "KARS", "KAT5", "KCTD10", "KDELR1", "KDM1A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC3", "MORF4L1", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYDGF", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA25", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "NDC1", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NF2", "NFAT5", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD5", "OTULIN", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PELO", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP1R21", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM23", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "REV1", "REXO4", "RFC1", "RFK", "RFTN1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTFDC1", "RTKN", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDHA", "SDHAF2", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMAD4", "SMARCA4", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG5", "SMG8", "SMPD4", "SMS", "SMU1", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SQLE", "SQOR", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM214", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNRC6B", "TOE1", "TOM1", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROAP", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSN", "TSPAN3", "TSPO", "TSPYL1", "TSR1", "TSR3", "TSSC4", "TST", "TSTA3", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WBP11", "WBP2", "WDR11", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR44", "WDR45", "WDR46", "WDR73", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YIF1A", "YIPF5", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H14", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZCRB1", "ZFC3H1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF503", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZWILCH", "ZZEF1", "ZZZ3"], "leading_proteins": ["ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "AP2A2", "ARIH2", "ATAD3B", "ATG7", "ATP11C", "ATP13A1", "ATP1B3", "ATP6V0A1", "BAG4", "CAPZA2", "CARS2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CKB", "CNDP2", "CNNM3", "COPG2", "CRNKL1", "CTBP2", "CTNNA1", "CUL3", "CUL4B", "CUL5", "DCUN1D5", "DNA2", "DNAJA2", "DNM1L", "DOCK1", "DYNC1LI2", "DYNLL2", "EIF2B1", "EIF2B2", "EIF5", "EMC3", "ERO1B", "EXOSC2", "EZR", "FAM98B", "FARP2", "FLOT2", "GATAD2B", "HDAC1", "HDAC6", "HK2", "HMOX2", "HNRNPLL", "HNRNPR", "IDH3A", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "LENG8", "LIG1", "LSG1", "LUC7L2", "MAEA", "MCM3", "MCM5", "MCM6", "METAP1", "MFN2", "MIPEP", "MRI1", "MRPL15", "MRPS11", "MRPS17", "MRPS30", "MSH3", "MSN", "NAE1", "NAP1L1", "NF2", "NSUN4", "NUBP2", "NUBPL", "NUCB2", "OPA1", "P4HA1", "PANK3", "PAPSS1", "PDIA3", "PDIA4", "PI4KB", "POLA1", "POLD1", "POLR1B", "POLR2B", "PRKAR1A", "PRMT1", "PRPSAP1", "PRPSAP2", "PTGES2", "RARS2", "RDX", "RECQL", "ROCK1", "RPL3", "SCAMP2", "SCARB2", "SCFD1", "SCO2", "SEC13", "SEC23A", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SLC25A1", "SLC25A32", "SLC25A4", "SNX6", "STAG1", "STAT3", "STX4", "STXBP3", "TCP1", "TIMM13", "TIMM17B", "TM9SF3", "TPM4", "TSR1", "TUBB4A", "TUBGCP2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "VBP1", "VDAC1", "VPS33A", "VPS33B", "VPS45"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9565fc0ad31c5b0319fce896f4997fd334956dd1 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Tetratricopeptide-like helical domain superfamily [IPR011990]", "2": "Nucleic acid-binding, OB-fold [IPR012340]", "3": "Chaperone J-domain superfamily [IPR036869]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/plot_0.png b/interpro_homologous_superfamily/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..25eb9d84aca91c51321b53185868a42d35eea6fe --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f31441aa236111bad67023b40d2e885b89f66a88b0a6b9ce2751a1b1b0ea257 +size 200122 diff --git a/interpro_homologous_superfamily/advanced/plot_1.png b/interpro_homologous_superfamily/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d61ece081665af86e75e6201997b4e83ef910a14 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:36f4b6bca7f8019dac0ddcd77f3c2f89c5eaa78555e98d474c1ece018b748e8e +size 214552 diff --git a/interpro_homologous_superfamily/advanced/plot_2.png b/interpro_homologous_superfamily/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..11f77e49a03db02ce1f1a636731a0338acf20152 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40d38a0406fa942ef55a2a97001a18b61e6ceefe5a24b30ab4766fd474a46f45 +size 203903 diff --git a/interpro_homologous_superfamily/advanced/plot_3.png b/interpro_homologous_superfamily/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..21ab0f6777fd25e0dc492fe31a850dc76284b71f --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31199ba571a876d954063a7f691e76bf2384e4ece8c668beb675984eac3eeeee +size 198107 diff --git a/interpro_homologous_superfamily/basic/idx2term.json b/interpro_homologous_superfamily/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6059717d422c3ae6951da8521aaec525eae06c14 --- /dev/null +++ b/interpro_homologous_superfamily/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Tetratricopeptide-like helical domain superfamily [IPR011990]", "2": "Nucleic acid-binding, OB-fold [IPR012340]", "3": "Chaperone J-domain superfamily [IPR036869]", "4": "FAD/NAD(P)-binding domain superfamily [IPR036188]", "5": "Alpha/Beta hydrolase fold [IPR029058]", "6": "Nucleotide-diphospho-sugar transferases [IPR029044]", "7": "Dbl homology (DH) domain superfamily [IPR035899]", "8": "Rho GTPase activation protein [IPR008936]", "9": "Protein kinase-like domain superfamily [IPR011009]", "10": "Kinesin motor domain superfamily [IPR036961]", "11": "PH-like domain superfamily [IPR011993]", "12": "Sec1-like superfamily [IPR036045]", "13": "Sec1-like, domain 2 [IPR027482]", "14": "C2 domain superfamily [IPR035892]", "15": "Winged helix-like DNA-binding domain superfamily [IPR036388]", "16": "EF-hand domain pair [IPR011992]", "17": "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "18": "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "19": "Ubiquitin-activating enzyme [IPR035985]", "20": "Phosphoribosyltransferase-like [IPR029057]", "21": "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "22": "PX domain superfamily [IPR036871]", "23": "TBP domain superfamily [IPR012295]", "24": "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "25": "B30.2/SPRY domain superfamily [IPR043136]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/plot_0.png b/interpro_homologous_superfamily/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..50e796d6067b99d58d147b6955ab88dff40bc404 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3831d7beda1fce9c2007f531554492b5560e5a42db16418f99e6869a597fb1a6 +size 145357 diff --git a/interpro_homologous_superfamily/basic/plot_1.png b/interpro_homologous_superfamily/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..13bb36d19842b952657fd49fe637bab61dafd330 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d68aab35d2e61428069bc35c14c9fdb6add7a79175715ae13d946d8d93121688 +size 150106 diff --git a/interpro_homologous_superfamily/basic/plot_10.png b/interpro_homologous_superfamily/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..1fbf0124a38e6d14efd7368bd0bd2230ba1944d2 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e340a100fbdb31d48de66c4a5061dae73afc410e1d10580c299c2c8d6c4c038 +size 148955 diff --git a/interpro_homologous_superfamily/basic/plot_11.png b/interpro_homologous_superfamily/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..1cc210f5748e53b3f5bb9ded7e4e633635dacf74 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f5da49e447c1cae0816cb326076332a919319b14265e5c307bea0fd6ee2a471 +size 150534 diff --git a/interpro_homologous_superfamily/basic/plot_12.png b/interpro_homologous_superfamily/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..9cfd551346266756bee0613d79ba75ea58471a66 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:39f096d5ec45abf554a9c2bbcf1406b2c62ad6b89dc3100c3adb91c0d9152f35 +size 135714 diff --git a/interpro_homologous_superfamily/basic/plot_13.png b/interpro_homologous_superfamily/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..6b9ab27483f65a26f65b2a56e4978ea241f2bf50 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95cff0ea5115526e2958a8e07df87da7710c167cdfa15fecf025d3bbf4255b9c +size 134811 diff --git a/interpro_homologous_superfamily/basic/plot_14.png b/interpro_homologous_superfamily/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a8f08f6d5612b238b8bfb3cb15acf8d51744f9b1 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac1cb0926d1bfe8c91312cbab153999179df08b8226f75be3c8957f57b01751f +size 148501 diff --git a/interpro_homologous_superfamily/basic/plot_15.png b/interpro_homologous_superfamily/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..86e3aa9e055f7182cdd194cc5a578d73f9cc17a3 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d62720df8f79974af7a6e975212915b871eb71803421e9070be00e1d9e540a12 +size 155696 diff --git a/interpro_homologous_superfamily/basic/plot_16.png b/interpro_homologous_superfamily/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..b135ebe1268f5be1ec196bdd4979ad2dd0032c48 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17b6e749de86aba2461ccdbe3ef78235f772d2d02e2d2812816d0f835dcc69cf +size 143306 diff --git a/interpro_homologous_superfamily/basic/plot_17.png b/interpro_homologous_superfamily/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..1dd84a6d625dd7815fb54ed8b8ca2f89e450a71c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2a033aea1eb8ef09639d9fb2f1289b283f65ce1a2493afa9830d25ad4b8ef20 +size 156025 diff --git a/interpro_homologous_superfamily/basic/plot_18.png b/interpro_homologous_superfamily/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..7a7be3bbd896ad9983dd8f6824a12465adbd9cda --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:575b29d90404fe848858906c3eb8045a5d081ffe3c38733c5a6129246849ff09 +size 153402 diff --git a/interpro_homologous_superfamily/basic/plot_19.png b/interpro_homologous_superfamily/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..050995e57b2b456be01d5072d7922ba27a246362 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abdd375dc4eb6a6f65f344258e7af77a5d75e2c58ed63e5ceb80e7d6c0eda69a +size 146144 diff --git a/interpro_homologous_superfamily/basic/plot_2.png b/interpro_homologous_superfamily/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..871b88d5f0ee6be71a47aa4e555336151f43d15c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f8c0fa6d99df861bf8623e2a05a1627159a59611cbb7f0e1ec4878c78de491f +size 139991 diff --git a/interpro_homologous_superfamily/basic/plot_20.png b/interpro_homologous_superfamily/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..809ebb77949e5e9c4f252a5c790f2b4da7bb4638 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cff221e35a99f8eaf758a1b08fe8affe2eaf797e949f5480fd673373aa26e349 +size 145890 diff --git a/interpro_homologous_superfamily/basic/plot_21.png b/interpro_homologous_superfamily/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..cf7365d5524b1f3fd4683458de65a69ed3d0e01f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aca84185b46dd334660a042e68db0cb4109027c59b35dad09e9bf0d13ac1e3fc +size 168665 diff --git a/interpro_homologous_superfamily/basic/plot_22.png b/interpro_homologous_superfamily/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..3af808ab25035b43623bb6ad0456b389fd870c12 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:371aeab1753b31071eb338c98a595d451a809996aaeea42f983a28efb1e58ea8 +size 149476 diff --git a/interpro_homologous_superfamily/basic/plot_23.png b/interpro_homologous_superfamily/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..30b12bc90987f2cf4c2b5bb3f972750e8e6a1ea0 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67202bf4df17518704ec215456eee5957b6f5a1085b0635c4bb948bb7913ff8a +size 138213 diff --git a/interpro_homologous_superfamily/basic/plot_24.png b/interpro_homologous_superfamily/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..8d81202900c2ee6056cf500edf3c18fbfcee9852 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41895a656ecde65289e38663257c4952e2f981665f88cefb5224703c71203650 +size 147356 diff --git a/interpro_homologous_superfamily/basic/plot_25.png b/interpro_homologous_superfamily/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..eea7884ef755cce308f9fa8657b4e2d28c584acd --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:196a20718b08b2a1d62c7d3e67981fc210a65e9ddc4b1e6018f97634ba3a5b5b +size 152640 diff --git a/interpro_homologous_superfamily/basic/plot_3.png b/interpro_homologous_superfamily/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..56feb2f88b545a4a01984ab0e9e19267096779d6 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79e5cefeece64c901835306d788f3fd2c1fadafd19c39deda1b2d4cde0983e26 +size 132509 diff --git a/interpro_homologous_superfamily/basic/plot_4.png b/interpro_homologous_superfamily/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..f9b73a833149ddcaa54a0847ea75f1386222156c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba8f91838264af02db6162d112e55f2fc83278258bde0a8128bf9fffac8c267b +size 145016 diff --git a/interpro_homologous_superfamily/basic/plot_5.png b/interpro_homologous_superfamily/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..9d995538be8e6842351a47bbece177199f012d79 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:54cde353bf5e1894b831b1e35e0f4be485a36801e6949e9ca513eddf60f3f7ab +size 131362 diff --git a/interpro_homologous_superfamily/basic/plot_6.png b/interpro_homologous_superfamily/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8390391c1abb8ee36db144736cee34e0e36767f9 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b04d4041457a5f8ec340abfe64ef0a168fc3a427ff3847f503c457e93ef8ad4e +size 143985 diff --git a/interpro_homologous_superfamily/basic/plot_7.png b/interpro_homologous_superfamily/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fc77d53313bb2929be97f0cc2ac3ad615bdba687 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de54fd09539c9d0a6ff05a8d1c26ad4105f2464e93633ded29ae3e04afbde0e7 +size 140564 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e300c563d865a746715368ebdb2579faa43539fe --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6a91469942d02fcdb9044fd815a74efe36a939f15e875207936498e3716c7e0 +size 139801 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ea60fde0fe0d6fb9f733fca399d1ea40cdd9d07d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27641e5989492effec7b6c28ce8fdef24dcf8787b4890d1379c8b6efbbcb67a0 +size 153937 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6ee9b9de59514f5c7e09590b2a419268cd5502a6 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2bcd3b370bf6b70a0190cfdaa2ca0fc9a51aa0f00fb79f7e8c9f4a1f239903bb +size 281050 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..365a04d62b8d3d822ca6ba438ed4e55cecf1cf1d --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 6 19 3.034614569403401 0.0024084325990028 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.013156992218303 0.0004434091565531 2.9874917190946567e-05 0.0004032504678998 +Tetratricopeptide-like helical domain superfamily [IPR011990] 29 86 2.731352891435386 0.006307489301109 22.856796116504853 85.5631067961165 0.5676132842696584 0.6143258973719493 7.683128498309678 5.891280215778877 0.9202004538980384 0.371378017802006 0.5513213948028619 0.4894004644804887 0.2385629344439445 9.22463489706222e-05 +P-type ATPase, cytoplasmic domain N [IPR023299] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.0983610682747182 0.0892170338783466 +P-type ATPase, A domain superfamily [IPR008250] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.0983610682747182 0.0892170338783466 +P-type ATPase, transmembrane domain superfamily [IPR023298] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.1060727287920157 0.09905667817091 +HAD superfamily [IPR023214] 4 18 2.180215907310998 0.0292414610113702 5.905339805825243 19.805825242718445 0.5764874318568467 0.4905542596212732 2.7813998415737995 2.7290535093395536 0.8549369097345116 0.3043048374614219 0.2285159407722543 0.4153631372956372 0.0463117823544705 0.1361256245763561 +HAD-like superfamily [IPR036412] 4 18 2.180215907310998 0.0292414610113702 5.905339805825243 19.805825242718445 0.5764874318568468 0.4905542596212732 2.7813998415737995 2.7290535093395536 0.8549369097345116 0.3043048374614219 0.2427225356114331 0.4374181157102795 0.0571243888921134 0.167212369248385 +Nucleic acid-binding, OB-fold [IPR012340] 14 40 2.0130317456525657 0.0441112897644098 14.883495145631068 40.74757281553398 -0.370458512096078 0.5886263783721093 7.189259749454186 2.8214450838537957 0.8787837478888605 0.3284009103859457 1.0 0.463832032870012 0.0723728978816966 0.0040466728259346 +Chaperone J-domain superfamily [IPR036869] 7 17 1.9831535239648832 0.0473502834758099 5.283980582524272 16.95145631067961 0.2877620197190211 0.6553182406991414 3.0031432852689477 2.283876115766552 0.674660578232377 0.2854789848222235 1.0 1.0 0.063688713570506 0.0359117122080593 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..82f1d6db899e77fb2131c3dacc8a6ee0e12376ec --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 1029, + "title": "Average number of proteins per term", + "value": 4.965014577259475 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6da2d6a7f18783e8fa26fe67d250eff4f4a7fd6b --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..98f5aa94f3c140fa3c91e79561e10395cd73bf97 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,157 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase-like, multi-helical [IPR016084] 0.9868617497760512 3.3849517614343614 0.0007119076424908 0.5194451201143706 0.0073255296412308 2 P30519 1 +Tim10-like domain superfamily [IPR035427] 0.9590922663481624 3.265502316427795 0.0010927011175554 0.6753488989845523 0.0091413776419881 2 Q9Y5L4 1 +DCN1-like, PONY binding domain [IPR042460] 0.9199761122723128 3.094280050594453 0.0019729116044051 0.8689440972759426 0.0126094785151112 2 Q9BTE7 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.7518618889276394 3.0346145694034012 0.0024084325990028 0.9163627535628412 0.0140862264514124 19 P53007,Q70HW3,Q9H2D1,Q9Y6C9,Q9UBX3,Q9BSK2 6 +Translation initiation factor IF2/IF5, zinc-binding [IPR016190] 0.8874290833084528 2.9490874024381863 0.0031871382626604 0.9625520240540084 0.015767140732104 2 P55010 1 +Translation initiation factor IF2/IF5, N-terminal [IPR016189] 0.8874290833084528 2.9490874024381863 0.0031871382626604 0.9625520240540084 0.015767140732104 2 P55010 1 +KA1 domain/Ssp2, C-terminal [IPR028375] 0.8722006569125134 2.880282399511214 0.0039731911250595 0.9833701710260634 0.0180106328972964 2 Q7KZI7 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.4381922962384931 2.731352891435386 0.006307489301109 0.9985129515909436 0.0235419281633245 86 Q86YR5,Q15006,Q32P28,Q96EY7,Q6ZXV5,Q7L5D6,P31948,Q9BZJ0,P50542,Q9BXJ9,O43242,P42345,O75153,Q9UJX4,Q6DKK2,O15091,O00411,O00231,O75718,Q6P3X3,Q9H0B6,Q9UPR3,Q9HCS7,Q9Y2L5,Q96EK5,Q9BQ70,Q9UJX2,Q86TV6,Q92552 29 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.8091967751567671 2.589569425815714 0.0096096043503424 0.9999516043539748 0.0320009154579364 2 Q9H267 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.8077037921767698 2.5825606859809525 0.0098070112835806 0.9999605794711258 0.0322796111830543 2 Q14185 1 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.8077037921767698 2.5825606859809525 0.0098070112835806 0.9999605794711258 0.0322796111830543 2 Q14185 1 +Porin domain superfamily [IPR023614] 0.9657849396634366 2.550675661934154 0.0107514328128119 0.9999852331664236 0.0337912051981048 4 P21796 1 +ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802] 0.8008360704688 2.550248434660536 0.0107646180325795 0.999985434313068 0.0337912051981048 2 P12277 1 +F-actin capping protein, alpha subunit, domain 1 [IPR042489] 0.7987458942968058 2.54039076138562 0.0110728677869571 0.9999894304416552 0.0341137154274817 2 P47755 1 +RGS domain superfamily [IPR036305] 0.7829202747088659 2.465397723267247 0.013686124135994 0.9999993056440768 0.039895245710872 2 Q92888 1 +Moesin tail domain superfamily [IPR008954] 0.922318494173887 2.3782454975691505 0.0173952403323263 0.999999985616965 0.0469808459369127 4 P35241,P26038,P15311 3 +NET domain superfamily [IPR038336] 0.7536578083009826 2.3250741099536136 0.0200679977611513 0.9999999991277856 0.052411090599555 2 O60885 1 +Carnitine o-acyltransferase, N-terminal [IPR042572] 0.7432069274410301 2.2744396135237896 0.0229395679635473 0.9999999999574256 0.0578549397904172 2 P23786 1 +Lamin tail domain superfamily [IPR036415] 0.8136200716845837 2.247958449733999 0.0245788395145998 0.999999999992436 0.0607827544035789 3 P20700,Q03252 2 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.8728153156317219 2.240228261847668 0.0250761077794481 0.9999999999955242 0.0608568747760663 5 Q8NB49,Q9HD20 2 +P-type ATPase, A domain superfamily [IPR008250] 0.8728153156317219 2.240228261847668 0.0250761077794481 0.9999999999955242 0.0608568747760663 5 Q8NB49,Q9HD20 2 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.8728153156317219 2.240228261847668 0.0250761077794481 0.9999999999955242 0.0608568747760663 5 Q8NB49,Q9HD20 2 +Dynein light chain superfamily [IPR037177] 0.7351448193490407 2.2351936362688023 0.0254046390983895 0.999999999996836 0.0612210155321845 2 Q96FJ2 1 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.7243953418931032 2.182616895239537 0.0290640345251818 0.999999999999934 0.0682805742612147 2 Q6NUQ1 1 +HAD superfamily [IPR023214] 0.6234048737689029 2.180215907310998 0.0292414610113702 0.9999999999999454 0.0683851440470454 18 Q8NB49,Q5TFE4,Q969T7,Q9HD20 4 +HAD-like superfamily [IPR036412] 0.6234048737689029 2.180215907310998 0.0292414610113702 0.9999999999999454 0.0683851440470454 18 Q8NB49,Q5TFE4,Q969T7,Q9HD20 4 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.7133472678411479 2.1282865275692933 0.0333133344347134 0.9999999999999992 0.0743588310918006 2 Q5T160 1 +Spermidine synthase, tetramerisation domain superfamily [IPR037163] 0.6954314720812222 2.039563126546543 0.0413938577988612 1.0 0.0883698748444569 2 P19623 1 +Nucleic acid-binding, OB-fold [IPR012340] 0.4553729509502227 2.0130317456525657 0.0441112897644098 1.0 0.0928231434919789 40 Q9Y2L1,Q8N5C6,P67809,Q13868,P15927,P33992,P35244,P62917,Q04837,P33991,Q14566,P62266,Q9Y3B2,P25205 14 +Chaperone J-domain superfamily [IPR036869] 0.6050676248684151 1.9831535239648832 0.0473502834758099 1.0 0.0966734954297786 17 Q96KC8,Q9NVH1,Q9NVM6,Q8IXB1,Q99543,O75937,Q9UBS4 7 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.6834876082412598 1.9799985664495872 0.0477036897659781 1.0 0.0970780225121358 2 Q9BSJ2 1 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.7414784931923784 1.923201074526939 0.0544548023758857 1.0 0.106731412656736 3 Q969Y2 1 +Myosin S1 fragment, N-terminal [IPR008989] 0.7338749943729879 1.8883958089365964 0.0589728335758756 1.0 0.1136386624523896 3 P35580 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5347149773028692 1.8007629928828393 0.071740244112562 1.0 0.1274969105212891 21 Q9Y6N5,Q14534,Q9UHG3,P00390,Q6NUM9 5 +Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616] 0.6461630337414165 1.7918425817834915 0.0731581856680687 1.0 0.1284637765400046 2 P09874 1 +WGR domain superfamily [IPR036930] 0.6461630337414165 1.7918425817834915 0.0731581856680687 1.0 0.1284637765400046 2 P09874 1 +NAP-like superfamily [IPR037231] 0.7079646360248818 1.7690404191387312 0.0768871296243882 1.0 0.1336433384856343 3 P55209 1 +Alpha/Beta hydrolase fold [IPR029058] 0.5189835813871265 1.744404995553603 0.0810884945375653 1.0 0.1370115942186449 22 P07099,Q8NCG7,Q9NUJ1,P50897,P42785 5 +HR1 repeat superfamily [IPR036274] 0.6360107494774424 1.74017511115275 0.0818282744994109 1.0 0.1376432803412357 2 Q16512 1 +DNA polymerase family B, thumb domain [IPR042087] 0.6965352449223349 1.7160461099187865 0.0861536033763248 1.0 0.1426716779016743 3 P28340,P09884 2 +DNA polymerase, palm domain superfamily [IPR023211] 0.6965352449223349 1.7160461099187865 0.0861536033763248 1.0 0.1426716779016743 3 P28340,P09884 2 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.6919927050530127 1.6949295238109594 0.0900887910146126 1.0 0.147128627953285 3 P47755 1 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.6919927050530127 1.6949295238109594 0.0900887910146126 1.0 0.147128627953285 3 P47755 1 +FERM superfamily, second domain [IPR035963] 0.6437878574295194 1.694229222316868 0.0902217339538609 1.0 0.147128627953285 11 P35241,P26038,P15311,P35240 4 +Zinc finger, PARP-type superfamily [IPR036957] 0.6195879366975237 1.6562031065947078 0.0976806943474808 1.0 0.1532216989078656 2 P09874 1 +DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599] 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.1532216989078656 2 P18858 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.6528054768637043 1.5815175479858388 0.1137597498623486 1.0 0.1739357839648688 9 Q86UY6,Q92993,P41227 3 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.6029263144450088 1.5633378403905425 0.1179731523069629 1.0 0.178521137829213 12 P35241,P26038,P15311,P35240 4 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.5971931919976143 1.5410174298660029 0.1233125439638826 1.0 0.1846995745834574 2 P52888 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7193660308709661 1.5320796647611796 0.1255027771763406 1.0 0.1871628372673253 4 P08183,P28288 2 +START-like domain superfamily [IPR023393] 0.7164625037346634 1.5195754192993418 0.128617719634327 1.0 0.189881827121553 4 Q9Y5P4,Q00169,O95433 3 +Prefoldin [IPR009053] 0.7143694141100073 1.5105571153139956 0.1309013271315808 1.0 0.1924249508834238 4 P61758,Q9NQP4 2 +DNA/RNA polymerase superfamily [IPR043502] 0.6969515839808926 1.4853214913330743 0.1374586814624461 1.0 0.1997810497526229 5 P28340,P09884,O00411,Q9UBZ9 4 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.6598312942794601 1.4543170846187252 0.145858415950975 1.0 0.2110946694986685 7 P22695 1 +PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946] 0.6386229355006595 1.444930117440345 0.1484775157108568 1.0 0.2142824174845325 3 Q9NZC3 1 +Restriction endonuclease type II-like [IPR011335] 0.5783816064496905 1.4437910893862207 0.1487977492448511 1.0 0.2144438150881678 2 Q9BQP7 1 +K Homology domain, type 1 superfamily [IPR036612] 0.4682148757229027 1.4373291575024678 0.1506244876962612 1.0 0.2164701087143196 23 Q9Y2W6,Q96PU8,Q15366 3 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.568527918781718 1.3927450770235223 0.1636968922121884 1.0 0.2291756490970637 2 P30876 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4788689876084834 1.3787873074667247 0.1679603412203787 1.0 0.2335424136589299 20 Q10472,Q9Y673,O60568,Q96IJ6,Q9NR50,Q9Y5P6,P46976,Q13144 8 +Creatinase/aminopeptidase-like [IPR036005] 0.6356452860338975 1.3414825101818983 0.1797638444803808 1.0 0.2440329762141317 7 P53582 1 +Glutamine synthetase/guanido kinase, catalytic domain [IPR014746] 0.6727816270341915 1.3308224294741426 0.1832474458817805 1.0 0.2477813690044049 4 O75879,P12277 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.247850778045425 3 P20585 1 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.247850778045425 3 P20585 1 +MutS, connector domain superfamily [IPR036678] 0.6139294133321779 1.32847458373546 0.1840213745643388 1.0 0.247850778045425 3 P20585 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.6018041862125638 1.2712422266389316 0.2036424884558374 1.0 0.2707340059703575 3 Q99797 1 +Pseudouridine synthase, catalytic domain superfamily [IPR020103] 0.6482471227927478 1.2701178711066865 0.2040426466989644 1.0 0.2709159786493347 5 O95900,Q9Y606 2 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.6561040417173474 1.25860716397735 0.2081722581426368 1.0 0.2760428526143986 4 Q99797,P42892 2 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.541057031949842 1.250276897099999 0.2111984148339492 1.0 0.2786194472617099 2 Q53H12 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.541057031949842 1.250276897099999 0.2111984148339492 1.0 0.2786194472617099 2 Q53H12 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.6430504470412102 1.2471307213020908 0.2123495700332931 1.0 0.2797793950886794 5 P42345,Q9UBF8 2 +Dbl homology (DH) domain superfamily [IPR035899] 0.6133236776084517 1.2371849171804843 0.2160184397192619 1.0 0.2839946040336726 7 O94887,Q92974,Q9H8V3,Q92888,Q9NZM3 5 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.5374738727978565 1.2317022921860452 0.2180603132764065 1.0 0.2862041611752836 2 P54709 1 +Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163] 0.5869997712173328 1.11437681891524 0.265117563810618 1.0 0.3401570737669899 7 Q9BW92 1 +High mobility group box domain superfamily [IPR036910] 0.4832058843799102 1.1074839030631785 0.2680847680428559 1.0 0.343108490442909 15 P09429,P26583,Q12873,Q00059 4 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.6075432218760556 1.0904215147011145 0.2755275088458027 1.0 0.3521960330463738 5 Q9NS86 1 +Rho GTPase activation protein [IPR008936] 0.528712469861404 1.0886163155528454 0.2763231188614319 1.0 0.3527748006307858 11 Q13576,Q13017,Q68EM7,Q07960,Q01968 5 +Protein kinase-like domain superfamily [IPR011009] 0.3114491403486198 1.0624743376898973 0.2880204020215478 1.0 0.3667982595051642 83 Q13555,Q6P3W7,P35790,Q16512,Q9Y4A5,Q13177,Q13043,Q00534,O15111,P42345,P54646,Q709F0,Q7KZI7,P42356,Q13464,P78362,P24941,P36507,O14757,P17252,Q9UBF8,P27361 22 +Kinesin motor domain superfamily [IPR036961] 0.4157831622327425 1.059115258267647 0.2895472918269326 1.0 0.3682869756364816 23 Q9Y4I1,Q9Y496,P35580,P33176,O60333,P35579,Q99661,O00139,Q9BW19,O95235,Q9NS87 11 +ERO1-like superfamily [IPR037192] 0.5001492982979979 1.0390559652971247 0.298778708839333 1.0 0.3795596190070044 2 Q86YB8 1 +Cullin homology domain superfamily [IPR036317] 0.5858691401904214 1.0371619995781576 0.2996603646151974 1.0 0.3802102530074453 6 Q13620,Q93034,Q13618 3 +HSP40/DnaJ peptide-binding [IPR008971] 0.5937278700441747 1.0297926838337013 0.3031073358827829 1.0 0.3831663988002255 5 Q9UBS4 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121] 0.5395764459756973 0.9792545892347144 0.327454201950315 1.0 0.4084246955234838 3 P06576 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.4138810106384101 7 P04350 1 +Tubulin/FtsZ, C-terminal [IPR008280] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.4138810106384101 7 P04350 1 +Tubulin, C-terminal [IPR023123] 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.4138810106384101 7 P04350 1 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.5534514717524148 0.9590628507194664 0.3375270837207322 1.0 0.4169452210667869 7 Q66K14 1 +Chromo-like domain superfamily [IPR016197] 0.50323074628307 0.9550673616892646 0.3395436329837551 1.0 0.4189333313432661 11 Q9UBU8,Q92993,P83916 3 +SNARE [IPR010989] 0.5308546164394241 0.9388901356088216 0.347787154343476 1.0 0.4280777294490872 3 Q12846 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.4300652022784325 2 P40763 1 +STAT transcription factor, coiled coil [IPR015988] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.4300652022784325 2 P40763 1 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.4300652022784325 2 P40763 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.4254392836156897 0.9251078385838316 0.3549098160867188 1.0 0.4342475633213241 18 Q9H7Z7 1 +Beta-grasp domain superfamily [IPR012675] 0.5294294870058878 0.917212834033934 0.3590311228779033 1.0 0.4387684387664637 8 Q9BW92 1 +TGS-like [IPR012676] 0.5346613275296336 0.8731949741197935 0.3825568137943582 1.0 0.4653084650051946 7 Q9BW92 1 +Anticodon-binding domain superfamily [IPR036621] 0.5315528124319668 0.8590986085009376 0.3902861149658299 1.0 0.4732706615515537 7 Q9BW92,P41250,A2RTX5 3 +PUA-like superfamily [IPR015947] 0.4956690048084431 0.8581371247896212 0.3908167497207615 1.0 0.4732706615515537 10 Q9ULC4 1 +50S ribosomal protein L30e-like [IPR029064] 0.531260673094154 0.857775624523558 0.3910163719752524 1.0 0.4732706615515537 7 P55769 1 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.4625261272021563 0.8484714529696367 0.3961754641722121 1.0 0.4762436362537457 2 P47897 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.4625261272021563 0.8484714529696367 0.3961754641722121 1.0 0.4762436362537457 2 P47897 1 +ISWI, HAND domain superfamily [IPR036306] 0.4610331442221594 0.8410337961544773 0.4003290015190921 1.0 0.4801148514721978 2 P28370 1 +PITH domain superfamily [IPR037047] 0.4410271722902321 0.7426513675047878 0.4576927804390642 1.0 0.541963027700572 2 O43396 1 +Sec1-like, domain 3a [IPR043127] 0.5102979299555153 0.7066351256053814 0.4797932545882903 1.0 0.5629501242546759 6 Q96AX1,Q9H267,Q9NRW7,Q8WVM8 4 +Sec1-like, domain 1 [IPR043154] 0.5102979299555153 0.7066351256053814 0.4797932545882903 1.0 0.5629501242546759 6 Q96AX1,Q9H267,Q9NRW7,Q8WVM8 4 +PH-like domain superfamily [IPR011993] 0.2913393343351129 0.6935206724423595 0.4879828572196794 1.0 0.5712563823424915 65 Q6IN85,P35240,P50570,Q8IYI6,Q96SU4,P15311,Q92888,Q9Y5P4,Q9NZM3,Q66K14,Q13464,Q01082,P19174,Q92974,Q06481,Q9BXW6,P35241,Q9Y2J2,O94887,Q9NPI6,Q15036,P26038 22 +Sec1-like, domain 2 [IPR027482] 0.4884593436326128 0.6681918984105589 0.5040111062544608 1.0 0.5866826112396382 7 Q96AX1,Q9H267,O00186,Q8WVM8,Q9NRW7 5 +Sec1-like superfamily [IPR036045] 0.4884593436326128 0.6681918984105589 0.5040111062544608 1.0 0.5866826112396382 7 Q96AX1,Q9H267,O00186,Q8WVM8,Q9NRW7 5 +RmlC-like cupin domain superfamily [IPR011051] 0.515356964925628 0.665515303886436 0.5057209584056013 1.0 0.5880077584173601 4 O00625 1 +Malonyl-CoA ACP transacylase, ACP-binding [IPR016036] 0.4237085697223073 0.6598284097101761 0.509363949803729 1.0 0.5902426850766184 2 P49327 1 +Acyl transferase domain superfamily [IPR001227] 0.4237085697223073 0.6598284097101761 0.509363949803729 1.0 0.5902426850766184 2 P49327 1 +CDC48 domain 2-like superfamily [IPR029067] 0.4566091830936948 0.6090966229440443 0.5424603958838592 1.0 0.6243755563361199 3 O43933 1 +S15/NS1, RNA-binding [IPR009068] 0.4936625256170323 0.6079852361453173 0.5431972658693749 1.0 0.6245251246699293 5 P23381 1 +AH/BAR domain superfamily [IPR027267] 0.4195548544256703 0.5832060885618834 0.5597545729350102 1.0 0.6414114204344381 12 Q9UKS6,Q9UQB8,Q9UNH7 3 +DUSP-like superfamily [IPR035927] 0.444079991470095 0.5571793629086085 0.5774048882273415 1.0 0.6565189281612535 3 Q86UV5 1 +C2 domain superfamily [IPR035892] 0.3341991286648835 0.5516371226825588 0.5811969971298869 1.0 0.660101225217057 25 Q14185,O14795,Q96N67,P19174,Q96PU5,Q16512,P17252,Q9NZM3 8 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.4390566851649414 0.5457158265209215 0.5852612911718809 1.0 0.66398441964263 9 Q8IYI6,Q93034,Q13618,Q9UPT5 4 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.2829715910497066 0.5270539563195397 0.5981561198195384 1.0 0.6750975019382923 52 P05455,P46063,P50579,P15927,O75381,Q5JVF3,Q92993,Q96HY6 8 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.4749550192871686 0.511239707867485 0.6091832173250091 1.0 0.6850814542376332 4 Q96GX9 1 +Initiation factor 2B-like, C-terminal [IPR042529] 0.472064535404854 0.5007107338860595 0.6165747168894946 1.0 0.6911278689316884 4 Q9BV20,P49770,Q14232 3 +Ribosomal protein L2, domain 2 [IPR014722] 0.4008832848724968 0.4933095610484261 0.6217938737331346 1.0 0.6954629305123864 12 P62917,P50914,P61254 3 +Homeobox-like domain superfamily [IPR009057] 0.3373603122652229 0.4909700432988317 0.6234476354150331 1.0 0.6963064827056621 22 Q96KC8,Q96G23 2 +PINIT domain superfamily [IPR038654] 0.3810092564944706 0.4688618448033466 0.6391683906407226 1.0 0.7110316475343822 2 Q8N2W9 1 +Ribosomal L18e/L15P superfamily [IPR036227] 0.4183981481805403 0.4557997594076142 0.6485339771501113 1.0 0.720671125796398 3 Q9P015 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.4106432222285435 0.3975664749795373 0.6909497768583135 1.0 0.7605790207030623 8 P04350 1 +Putative DNA-binding domain superfamily [IPR009061] 0.3633920573305436 0.3973634028989329 0.6910994988895658 1.0 0.7605790207030623 2 Q9UI36 1 +Cobalamin-binding domain superfamily [IPR036724] 0.3624962675425472 0.3938652739171739 0.6936805097119514 1.0 0.7617900154680876 2 P22033 1 +Translation protein SH3-like domain superfamily [IPR008991] 0.3941216130391338 0.3900984091797829 0.6964637791282875 1.0 0.7640311606855094 10 P46778,P50914,P62917,P61254 4 +EF-hand domain pair [IPR011992] 0.2691273653704709 0.372982855020421 0.7091612044379942 1.0 0.7754802118668396 50 Q15293,P80303,O43852,Q03001,Q14651,Q9Y4J8,Q14257,Q13813,Q66K14 9 +Ribosomal protein S11 superfamily [IPR036967] 0.3529411764705867 0.3574447859082388 0.7207588539190626 1.0 0.7845745106724236 2 P82912 1 +Aspartate decarboxylase-like domain superfamily [IPR009010] 0.4299372572453139 0.3570992804554843 0.7210174831293565 1.0 0.7845745106724236 4 O43933,Q8NB90,P55072 3 +HIT-like superfamily [IPR036265] 0.3856033452807541 0.3385513660617088 0.7349477252743333 1.0 0.7952273494293259 3 Q69YN2,Q96C86 2 +Band 7/SPFH domain superfamily [IPR036013] 0.4019853971167966 0.3303053336201033 0.7411692632486075 1.0 0.8011167771878331 7 Q9UJZ1,Q14254 2 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.3445804717826141 0.3269805052477155 0.7436826300455626 1.0 0.8020120057177739 2 Q9UBF2 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.2730086890347317 0.3250871177594817 0.7451151384511097 1.0 0.8020120057177739 40 Q9BV86,O60294,P21964,O14744,Q99873,Q96CB9,Q8N4J0,Q6FI81,Q96FX7 9 +Histone deacetylase domain superfamily [IPR037138] 0.3724611708482556 0.2961649969772235 0.767104078690912 1.0 0.817979375101501 3 Q9UBN7,Q13547 2 +Bromo adjacent homology (BAH) domain superfamily [IPR043151] 0.4090230056767262 0.2938243159022851 0.768892153400851 1.0 0.819037293840037 4 Q86U86,P26358,Q13330 3 +Kelch-type beta propeller [IPR015915] 0.3572711887572701 0.2508809159386704 0.8019061795174667 1.0 0.8489315418965774 3 O60294 1 +Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864] 0.3040357097942315 0.2105165841045351 0.8332645094198203 1.0 0.8776143093070575 17 P49591,P41250,Q9Y285,A2RTX5,Q9BW92 5 +Ureohydrolase domain superfamily [IPR023696] 0.3725724529429275 0.1988601176372787 0.8423721678951366 1.0 0.885985801760011 4 Q9UBN7,P78540,Q13547 3 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.2822588268116746 0.1856755918142631 0.8526991703659741 1.0 0.8944214539312817 22 Q86XL3,Q9P2R3,Q9BQG2,Q9H078 4 +BAG domain superfamily [IPR036533] 0.2959092266348068 0.1793221223207214 0.8576847772879621 1.0 0.8983777996922121 2 O95429 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.3090003499309928 0.1361077009430663 0.8917361397129504 1.0 0.925929856472882 3 P35221 1 +Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080] 0.3120702044300855 0.1322631220781861 0.8947761753839074 1.0 0.9281498835383476 11 Q5T160,P54136,Q9HA77,P49589 4 +Ubiquitin-activating enzyme [IPR035985] 0.3197726592880621 0.122004512545887 0.9028954444766596 1.0 0.9346875375920348 8 Q13564,P22314,Q9UBT2,A0AVT1,Q8TBC4,O95352,Q9GZZ9 7 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.940495951188598 3 P30876,Q9H9Y6 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.2956989247311742 0.1126169158569269 0.9103342734536868 1.0 0.940495951188598 3 P30876,Q9H9Y6 2 +Phosphoribosyltransferase-like [IPR029057] 0.3131917439425631 0.1083115962475425 0.9137485242577672 1.0 0.9424947729539443 8 Q14558,Q9NRG1,Q06203,P00492,P07741,O60256,P11908 7 +NTF2-like domain superfamily [IPR032710] 0.3129707159624833 0.1078674235965106 0.9141008585112114 1.0 0.9424947729539443 8 O43615 1 +P-loop containing nucleoside triphosphate hydrolase [IPR027417] 0.2109793150861052 0.0928827067194995 0.9259967443882656 1.0 0.9494914644396678 307 Q16181,P35580,P08183,P57772,Q9Y5M8,Q3YEC7,P28288,Q8WVC6,Q96GQ7,Q14566,Q9BW19,Q9NS87,Q7LGA3,P42285,Q15126,Q14147,Q8WVB6,P25705,Q8IYB8,O60231,O95235,Q15019,Q12959,P46199,P25205,Q7Z478,Q14141,Q96RP9,P51530,P46063,Q9H078,O00429,P19447,P33991,P35579,P36915,P20338,Q9H2U1,Q9NRK6,P51159,Q9P0V9,Q9Y4B4,Q9Y5Y2,P04183,Q13017,P51151,P62191,Q14344,Q7Z7L1,Q92620,Q9NUQ8,Q5T9A4,Q9Y2R4,O60313,Q86WJ1,O43237,O95140,Q96TA2,O14981,O43681,P33176,Q9H089,Q8NC60,Q9HCE1,Q99661,Q96RR1,Q9BUQ8,Q9UNY4,P18074,Q9Y496,P51532,O60333,P20585,P63000,P52701,Q9UQE7,Q92499,Q99741,Q969Y2,Q8TB37,Q8IWA4,P50570,Q9NVA2,O00139,Q9BUJ2,Q9H0S4,Q9Y6G9,O14646,Q00839,Q9UG63,Q9Y3D8,Q12873,P06576,Q9Y4I1,P33992,P54132,Q9NVI7,Q9Y295 98 +PX domain superfamily [IPR036871] 0.2957070415122567 0.0923459786928915 0.9264231586952638 1.0 0.9494914644396678 11 Q9Y5X1,Q9Y5X3,Q9UNH7,O60749,Q13596,Q15036 6 +TBP domain superfamily [IPR012295] 0.3082212257100254 0.083729486701254 0.933271512459255 1.0 0.9546087339170708 6 O95782,O94973,Q9Y678,Q9UBF2,P63010 5 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.3082212257100254 0.083729486701254 0.933271512459255 1.0 0.9546087339170708 6 O95782,O94973,Q9Y678,Q9UBF2,P63010 5 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.2972811472960799 0.071527965266849 0.9429775684893288 1.0 0.9635788659141205 4 Q96CW1,Q9BXS5,P48444 3 +CAP Gly-rich domain superfamily [IPR036859] 0.2601452432366565 0.0407587355826319 0.9674882362373955 1.0 0.9815973398376135 4 P30622 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.2494771437107793 0.0350026098012872 0.9720776598294552 1.0 0.9835476027182982 4 Q6PCE3,Q96G03,O95394 3 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.2494771437107793 0.0350026098012872 0.9720776598294552 1.0 0.9835476027182982 4 Q6PCE3,Q96G03,O95394 3 +B30.2/SPRY domain superfamily [IPR043136] 0.244404075065084 0.0099401735880877 0.9920690195687109 1.0 0.9978876061937472 13 Q9BUJ2,Q9C037,P14373,O15344,Q00839 5 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..abf34fd3a8bb3e4cea996fd6a5990c81837a2231 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Autophagy protein Atg5, UblA domain [IPR042527]", "Autophagy protein Atg5, helix rich domain [IPR042526]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CBP/p300, atypical RING domain superfamily [IPR038547]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coactivator CBP, KIX domain superfamily [IPR036529]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, Y-family, little finger domain superfamily [IPR036775]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deltex, C-terminal domain superfamily [IPR039399]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavinator of succinate dehydrogenase superfamily [IPR036714]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone chaperone ASF1-like superfamily [IPR036747]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "Mur ligase, C-terminal domain superfamily [IPR036615]", "Mur-like, catalytic domain superfamily [IPR036565]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily [IPR037073]", "Nuclear receptor coactivator, interlocking [IPR009110]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinolinate phosphoribosyl transferase, N-terminal domain superfamily [IPR037128]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Rad4, beta-hairpin domain 3 superfamily [IPR042488]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rev1, C-terminal domain superfamily [IPR038401]", "Reverse transcriptase/Diguanylate cyclase domain [IPR043128]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD MH1 domain superfamily [IPR036578]", "SMAD-like domain superfamily [IPR017855]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Ski-like, DNA-binding domain superfamily [IPR037000]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "T-box superfamily [IPR036960]", "TAZ domain superfamily [IPR035898]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor, Skn-1-like, DNA-binding domain superfamily [IPR008917]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transglutaminase-like superfamily [IPR036985]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1H", "ATXN10", "ATXN2", "AURKA", "BABAM1", "BACH1", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCL2L13", "BCR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPV", "CERS2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHORDC1", "CHTF18", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COL4A3BP", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CWF19L1", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYP51A1", "DACH1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D5", "DCXR", "DDB1", "DDHD2", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTCD1", "PTCD3", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REL", "RELA", "REPS1", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTKN", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STUB1", "STX12", "STX4", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TMA16", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMYND8", "ZNF24", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCB10", "ABCD3", "ABCF2", "ABCF3", "ABHD10", "ACAD11", "AGK", "AHSA1", "AK6", "ALG5", "ANAPC5", "ANKFY1", "ANKLE2", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "APIP", "APLP2", "APRT", "ARCN1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ASNA1", "ATAD3A", "ATAD3B", "ATG7", "ATP11C", "ATP13A1", "ATP1B3", "ATP5A1", "ATP5B", "BAG4", "BAIAP2", "BLM", "BRD4", "BTAF1", "CALU", "CAMK2G", "CAPZA2", "CARNMT1", "CARS", "CARS2", "CBX1", "CDC23", "CDC6", "CDK2", "CDK6", "CERS2", "CHD1", "CHD1L", "CHD3", "CHEK1", "CHKA", "CHTF18", "CHUK", "CIAPIN1", "CKB", "CLIP1", "CLPB", "CLUH", "COL4A3BP", "COMT", "COPG1", "COPG2", "CPT2", "CRNKL1", "CRTAP", "CTNNA1", "CUL3", "CUL4B", "CUL5", "CWF19L1", "DACH1", "DAGLB", "DCAKD", "DCP1A", "DCPS", "DCUN1D5", "DDRGK1", "DDX1", "DDX23", "DDX27", "DDX47", "DDX52", "DHX16", "DHX29", "DHX34", "DHX36", "DHX38", "DIS3", "DLG1", "DNA2", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC17", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DRG1", "DST", "DTNA", "DYNC1LI1", "DYNC1LI2", "DYNLL2", "ECE1", "ECT2", "EEFSEC", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF5", "EMC2", "EPB41L3", "EPHX1", "ERCC2", "ERCC3", "ERO1B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EZR", "FARP2", "FARSA", "FASN", "FLOT2", "GALNT1", "GARS", "GATB", "GDE1", "GET4", "GFM1", "GMPPA", "GMPPB", "GNA13", "GNL1", "GPSM1", "GSR", "GTPBP3", "GYG1", "HDAC1", "HDAC6", "HMGB1", "HMGB2", "HMOX2", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "IQGAP2", "ITSN2", "KAT5", "KIAA0391", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIFC1", "KLC2", "LANCL2", "LCMT2", "LIG1", "LMNB1", "LMNB2", "LSG1", "MAP2K2", "MAPK3", "MARK2", "MCM3", "MCM4", "MCM5", "MCM6", "MCTS1", "METAP1", "METAP2", "MFN1", "MFN2", "MGME1", "MID1", "MIPEP", "MORF4L1", "MOV10", "MRI1", "MRPL15", "MRPS11", "MRPS27", "MSH3", "MSH6", "MSN", "MTA1", "MTCH2", "MTIF2", "MTOR", "MUT", "MYH10", "MYH9", "MYO5A", "NAA10", "NAA15", "NAA40", "NAE1", "NAP1L1", "NEDD4L", "NF2", "NOA1", "NSUN4", "NT5C3B", "NT5DC1", "NTMT1", "NUBP2", "NUBPL", "NUCB2", "NUDT12", "OCRL", "OPA1", "OSBPL1A", "OSBPL9", "P3H1", "PACSIN3", "PAK2", "PARP1", "PBRM1", "PCBP2", "PCID2", "PCYOX1", "PEX1", "PEX14", "PEX5", "PFDN4", "PGM2", "PGM2L1", "PGM3", "PI4KA", "PI4KB", "PIAS4", "PIR", "PITPNA", "PKN1", "PLCG1", "PLOD3", "PLS1", "PMVK", "POLA1", "POLD1", "POLR1B", "POLR2B", "POLRMT", "PPAT", "PPP4R3A", "PPT1", "PRCP", "PRKAA2", "PRKCA", "PRMT1", "PRMT5", "PRPS2", "PRPSAP1", "PRPSAP2", "PRTFDC1", "PSMC1", "PSMD11", "PSMD3", "PTCD3", "PTGES2", "PUS1", "QARS", "QKI", "RAB27A", "RAB4A", "RAB9A", "RABL6", "RAC1", "RAD54L2", "RARS", "RARS2", "RCN1", "RCN2", "RDX", "RECQL", "RETSAT", "REV1", "RINT1", "ROCK1", "RPA2", "RPA3", "RPL14", "RPL21", "RPL26", "RPL8", "RPS23", "SARS", "SCFD1", "SCYL2", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SKIV2L2", "SLC25A1", "SLC25A10", "SLC25A26", "SLC25A32", "SLC25A33", "SLFN11", "SMARCA1", "SMARCA4", "SMC3", "SMG5", "SNU13", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SPATA5", "SPTAN1", "SPTBN1", "SQLE", "SQOR", "SRBD1", "SRM", "SRPK2", "SRPRB", "SSB", "SSBP1", "STAT3", "STIP1", "STK4", "STOML2", "STX4", "STXBP3", "SUPV3L1", "TARS2", "TARSL2", "TBC1D9B", "TCF25", "TDRKH", "TFAM", "THOP1", "TIMM13", "TIMM44", "TK1", "TMTC3", "TRAPPC8", "TRIM27", "TRIM4", "TRMT61A", "TRRAP", "TRUB2", "TTC19", "TTC27", "TTC7B", "TTF2", "TUBB4A", "TUBGCP2", "TWNK", "TXNL1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UNC13B", "UQCRC2", "USP48", "VBP1", "VCP", "VDAC1", "VPS33A", "VPS33B", "VPS45", "WARS", "XAB2", "YBX1", "YME1L1"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3f7ed010e609cb2d478812469684526e33e99d7b --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a59c80c858226ea20205b21c559aa76917168475826eb42494483f820857453 +size 75520 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5fa813e137e3d320ab19f482359390db8fd8e457 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 2 5 2.240228261847668 0.0250761077794481 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 1.0 1.0 0.0983610682747182 0.0892170338783466 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2c134bd7e3df495d09b7fa3de06353ab532ab736 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 5, + "title": "Average number of proteins per term", + "value": 2.2 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9521f1558d0fefec5db854524f736a833b4b867e --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cd39745b1987852d2bb0a518dc563c2daadd2db7 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.8728153156317219 2.240228261847668 0.0250761077794481 0.1192481413508161 0.0417935129657468 5 Q8NB49,Q9HD20 2 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..46407a8a367da93f1c3c03aea4b2718b3815302f --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Rapamycin-insensitive companion of mTOR, phosphorylation-site [IPR029259]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "EIF5A", "FASN", "LDLR", "NOTCH2", "RICTOR", "SLIT2"], "leading_proteins": ["ATP11C", "ATP13A1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..16260996bf19c8292beaf447210c66dd33c703a5 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:571408ea2cfb1d0ce9641a1fa8e86f3c27b646691d4e1b607894cc4c0b09a972 +size 194002 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b08b55f8987062cedfd4b186182330c9b52f6e6 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]", "2": "Spectrin repeat [IPR002017]", "3": "Spectrin/alpha-actinin [IPR018159]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bcdb076304977ee57cf7eb6b88b5d09c39a1de45 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4a19456daf52d418a19bd0f6f267eb9139a9b7b08c420412d4e93aa09065661 +size 145707 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..654dc7df114a1dcd91afbb11d3aac9329e74018d --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ded18b37e4e3ddadfa972ced9aa091bbbb570debd89d6be1047f160dd4fa1370 +size 142359 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0ca2666444626d1a830a894e99be9a2746395f2c --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:553f367c552dfbc6093dadbd93797da6e2af9ba806acf1fca46b5d0048f92bba +size 129367 diff --git a/interpro_repeat/basic/plot_3.png b/interpro_repeat/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a500a6cb0f01259e671d11d2801b304892a833cf --- /dev/null +++ b/interpro_repeat/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a906c8888499f4596d359ef97673901feb2a9c4e38967d926563c235b37327d5 +size 139780 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fdf93c9a7d73b5cd471056237caf98d6783839be --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66566c75c355d14dff384a4bd427fde2ad69af33abc01210763594172948fd7b +size 89917 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3eddcdb18dc0e7420956773526ebbb87ff57f601 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 6 19 3.034614569403401 0.0024084325990028 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.013156992218303 0.0004434091565531 2.9874917190946567e-05 0.0004032504678998 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..01b7d0bc844cce6c9a72c9bce53972080348d451 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 82, + "title": "Average number of proteins per term", + "value": 5.524390243902439 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9d64456ee663b32625b8c0720261c9ca0381315e --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e8a239f55cb43b0a5f53c88ced9277421e81c5dc --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,14 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7518618889276394 3.0346145694034012 0.0024084325990028 0.1794083529590308 0.0116171454775429 19 P53007,Q70HW3,Q9H2D1,Q9Y6C9,Q9UBX3,Q9BSK2 6 +Protein prenyltransferase, alpha subunit [IPR002088] 0.8957226897515386 2.6046878820821515 0.009195798756532 0.531183559502574 0.0245269172729999 3 P49354 1 +Hexapeptide repeat [IPR001451] 0.7497013142174387 1.9607233762685543 0.049911300628944 0.9849803260549964 0.0951796895714746 3 Q9Y5P6,Q13144 2 +Pentatricopeptide repeat [IPR002885] 0.7470236435450059 1.650792838291779 0.0987808830087324 0.9998022609532388 0.1528308001267181 4 Q92552,Q96EY7 2 +Tetratricopeptide repeat [IPR019734] 0.3999337740352072 1.6257444216626624 0.1040040359564054 0.9998772288341378 0.1579320546004674 46 Q6DKK2,Q86YR5,P50542,Q15006,Q9BXJ9,Q6P3X3,Q86TV6,Q9H0B6,Q6ZXV5,Q9HCS7,P31948,Q9UJX4,Q9UJX2 13 +BIR repeat [IPR001370] 0.5849507315616642 1.4777821409143796 0.1394661000514476 0.9999955231281994 0.1938342407494696 2 Q9NR09 1 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.6274506239929184 1.3922727663862478 0.1638398150668076 0.999999575636819 0.216691368314165 3 Q8WUH2 1 +Tetratricopeptide repeat 2 [IPR013105] 0.6628784741345353 1.287940059901611 0.1977668291803471 0.9999999857881552 0.242042984966992 4 Q6P3X3 1 +HEAT, type 2 [IPR021133] 0.4824301874771498 0.9755612429400118 0.3292819386161936 0.999999999999994 0.380297450232787 13 Q9BU89,Q86Y56,Q9P260 3 +Spectrin repeat [IPR002017] 0.5128047298732915 0.888851804195408 0.3740827303127014 1.0 0.4202025189813906 9 P46939,Q01082,Q03001,Q13813,Q8WXH0,P12814 6 +Leucine rich repeat 4 [IPR025875] 0.470131421744309 0.6666399652940452 0.5050021346461384 1.0 0.5521356672131114 3 Q8N1G4,Q13045 2 +Spectrin/alpha-actinin [IPR018159] 0.4302025139406564 0.5877587563586331 0.5566942310514769 1.0 0.6006437756081724 11 P46939,Q01082,Q03001,Q13813,Q8WXH0,P12814 6 +HAT (Half-A-TPR) repeat [IPR003107] 0.4361289323818763 0.4986315312236112 0.6180389876976857 1.0 0.6497332947591056 8 Q9BZJ0 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1f574ce272e592bc6e6e545d375a29f56bd3b62a --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "RPEL repeat [IPR004018]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "ATG16L1", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC23", "CDC27", "CDC40", "CHAF1B", "CIAO1", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DMD", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GNB1", "GPSM1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HTT", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KIAA1468", "KIDINS220", "KLC1", "KLC2", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "L3MBTL3", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MED16", "MIOS", "MKI67", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "OSBPL1A", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHACTR4", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTAR1", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "REV1", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SRP72", "STIP1", "STRAP", "STRN", "STRN3", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TLE4", "TMTC3", "TOMM34", "TOMM70", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WRAP53", "XAB2", "XIAP", "XPO1", "YTHDC2", "ZC3H7B", "ZFC3H1"], "leading_proteins": ["ACTN1", "ANAPC5", "BIRC6", "CDC23", "CRNKL1", "DNAAF5", "DOHH", "DST", "EIF2B5", "EMC2", "FLII", "FNTA", "GMPPB", "GPSM1", "KIAA1468", "KLC2", "LRRC47", "MRPS27", "MTCH2", "NAA15", "PEX5", "PTCD3", "SLC25A1", "SLC25A10", "SLC25A26", "SLC25A32", "SLC25A33", "SPTAN1", "SPTBN1", "STIP1", "SYNE2", "TGFBRAP1", "TMTC3", "TTC19", "TTC27", "TTC7B", "UTRN", "XAB2"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c5e0dcf4f061a62c7b361d40f233e9bd20902335 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrion organization", "1": "Transmembrane transport", "2": "Mitochondrial transmembrane transport", "3": "Mitochondrial transport", "4": "Protein localization to mitochondrion", "5": "Protein targeting to mitochondrion", "6": "Anion transmembrane transport", "7": "Protein targeting", "8": "Mitochondrial membrane organization", "9": "Protein localization to organelle"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..479a20250caeaf8b04a04a0c19aa0320e531c1d5 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a72504203b0d3b098415bf927bbb4163fd4402988d37c3a704d637f07c1bc521 +size 226115 diff --git a/msigdb_gobp/advanced/plot_1.png b/msigdb_gobp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7c43bd998c704814854718d939427a0de9d069ee --- /dev/null +++ b/msigdb_gobp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4159cbdf96855e5c080453ff8e0bf2b9b47a6bbf3d983935861625a98eabcbe1 +size 232584 diff --git a/msigdb_gobp/advanced/plot_2.png b/msigdb_gobp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..fa63fa7df848b9e13f5885dcbb5d24630d2d71d4 --- /dev/null +++ b/msigdb_gobp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d5895b2cd732e26997f2a795b317bfcd70c3e2c90c37713e19767ed7f0684bb +size 211235 diff --git a/msigdb_gobp/advanced/plot_3.png b/msigdb_gobp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..33161f824b919cb45f850ceb85d9d095dc933582 --- /dev/null +++ b/msigdb_gobp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f72850a99f690583ebf8445453820097ae0bd45b0a7e13de843522d2bdce0dfe +size 212884 diff --git a/msigdb_gobp/advanced/plot_4.png b/msigdb_gobp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8183665fba6f040337ceb8d1a254f6025c59b8ec --- /dev/null +++ b/msigdb_gobp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b16c62af7aae4af17048a4c591042fbba20269861461cc6054c62ff2e399ebba +size 208361 diff --git a/msigdb_gobp/advanced/plot_5.png b/msigdb_gobp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..96b798a5217976dd947eacd7e01bbd3f563a5dbb --- /dev/null +++ b/msigdb_gobp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5672c1f892559d868a0ad323dad9ad1fd29b8d20727578e6f13df21a596dc1d +size 207430 diff --git a/msigdb_gobp/advanced/plot_6.png b/msigdb_gobp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..3ab40895deb35573bbb16333892aa1f2ba579d26 --- /dev/null +++ b/msigdb_gobp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:355ef7019360592c2c17aa6f59d10e74d89b1d37b834169b51bc29cc1c9ca3cf +size 207248 diff --git a/msigdb_gobp/advanced/plot_7.png b/msigdb_gobp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..32620e5dbebe049548f43c9431c5df1f45f3edaf --- /dev/null +++ b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9374be84456917e9d3f21846cbe5dd65421c5618cbf23e44fae67b094e3ad94 +size 216991 diff --git a/msigdb_gobp/advanced/plot_8.png b/msigdb_gobp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..87b3341873c0f67c650bd559bc9151f4fc9a7e74 --- /dev/null +++ b/msigdb_gobp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d0d56e19bb33005deb10b0025216bdfb0912c226132ebe54e90301dcce7078f +size 209885 diff --git a/msigdb_gobp/advanced/plot_9.png b/msigdb_gobp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..eb3fa9ab8d9c596d519b5c2753feff688d2783e6 --- /dev/null +++ b/msigdb_gobp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1422b53d66975109aff924afb7a45d62a820aad2157b5c318abd80a2aad55b20 +size 227343 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c6c660385a05cfb5efeb5944087e545d5b1cce73 --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrion organization", "1": "Transmembrane transport", "2": "Mitochondrial transmembrane transport", "3": "Mitochondrial transport", "4": "Protein localization to mitochondrion", "5": "Protein targeting to mitochondrion", "6": "Anion transmembrane transport", "7": "Protein targeting", "8": "Mitochondrial membrane organization", "9": "Protein localization to organelle", "10": "Carboxylic acid transport", "11": "Ion transport", "12": "Mitochondrial gene expression", "13": "Anion transport", "14": "Organic acid transport", "15": "N terminal protein amino acid modification", "16": "Ion transmembrane transport", "17": "Mononuclear cell differentiation", "18": "Homeostasis of number of cells", "19": "Protein insertion into membrane", "20": "Protein import", "21": "Cell recognition", "22": "Establishment of protein localization to organelle", "23": "Mitochondrial respiratory chain complex assembly", "24": "Membrane lipid biosynthetic process", "25": "Regulation of golgi organization", "26": "Regulation of macroautophagy", "27": "Inner mitochondrial membrane organization", "28": "Leukocyte differentiation", "29": "Neuron apoptotic process", "30": "T cell differentiation", "31": "T cell activation", "32": "Protein localization to endoplasmic reticulum", "33": "Positive regulation of translation", "34": "Localization within membrane", "35": "Stem cell proliferation", "36": "Mitochondrial rna metabolic process", "37": "Membrane organization", "38": "Golgi organization", "39": "Negative regulation of neuron apoptotic process", "40": "Mitochondrial translation", "41": "Organelle disassembly", "42": "Sterol metabolic process", "43": "Dna geometric change", "44": "Cytoplasmic microtubule organization", "45": "Protein ufmylation", "46": "Endomembrane system organization", "47": "Response to mitochondrial depolarisation", "48": "Regulation of catabolic process", "49": "Alcohol biosynthetic process"} \ No newline at end of file diff --git a/msigdb_gobp/basic/plot_0.png b/msigdb_gobp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7aff0101a71e72fde26cbecba550cb43bb8e0649 --- /dev/null +++ b/msigdb_gobp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aac466d8c8a218a3658bc0ae3e4e1f1e819d32697d25918220aab8f977d18050 +size 146600 diff --git a/msigdb_gobp/basic/plot_1.png b/msigdb_gobp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c8f2c1581a42043e7189525fbe6f33578a003b45 --- /dev/null +++ b/msigdb_gobp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21499aa9734b1e35f90af74144a326c1a9c2551c1c048e475b7fbd615352e9f0 +size 143964 diff --git a/msigdb_gobp/basic/plot_10.png b/msigdb_gobp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..a0bae347606c5e8fcebda78e5734887f2ab4a9f1 --- /dev/null +++ b/msigdb_gobp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab440d4454e4da6e62a6e780e6d0cc5a3a1ff7a2a1d179308dfa41c14f899a20 +size 141086 diff --git a/msigdb_gobp/basic/plot_11.png b/msigdb_gobp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..ac3320292251b61f39313ab91e71396e32fd806c --- /dev/null +++ b/msigdb_gobp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:98ab27abf8f3ce20807e1b0e2d01c7d94289acbc21281a0a88a13b818ae4ac47 +size 139216 diff --git a/msigdb_gobp/basic/plot_12.png b/msigdb_gobp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..cff9f93aaccc1b249c6c2378c8cb5f975f0eade6 --- /dev/null +++ b/msigdb_gobp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e67cd0c9c302a3354dfe7661e611d032905e65665e6216800347bb123a44854 +size 149305 diff --git a/msigdb_gobp/basic/plot_13.png b/msigdb_gobp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..a1987da914c33b3a5d5770af76c72dbcd442c66c --- /dev/null +++ b/msigdb_gobp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f13569d5587cc7fa22b11d8ed348c50895b7273daa6316c7ea07921b866dd81 +size 131448 diff --git a/msigdb_gobp/basic/plot_14.png b/msigdb_gobp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..f14ef8bc0c1ab96a96b4b03f06523921ae533268 --- /dev/null +++ b/msigdb_gobp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89574d5d9e2cc7fda6e6a49537504d1ce9bc67da73fc9e4b14f9111155f59309 +size 140753 diff --git a/msigdb_gobp/basic/plot_15.png b/msigdb_gobp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..eb76e9ad29c8cf94350ea48d970530b494af9c4e --- /dev/null +++ b/msigdb_gobp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5c1bafe0a264038cc023a70aec65f9b3eb001817439a262557e9de4a5f3f0cd +size 142428 diff --git a/msigdb_gobp/basic/plot_16.png b/msigdb_gobp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..98a59a9e3dc3dc0322e7a1f874be712fa8914cd9 --- /dev/null +++ b/msigdb_gobp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0efa86e60ca34a2c918e306a2d98ece9f1703615816bae82e0749ee6c27d117f +size 141786 diff --git a/msigdb_gobp/basic/plot_17.png b/msigdb_gobp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..4e4a872ad8a128ec196f79720944444c6688a505 --- /dev/null +++ b/msigdb_gobp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43a204e5df1b7348cf5c61a64245289c59d1c69810a7ab0a9bad3d3336a3e13b +size 139054 diff --git a/msigdb_gobp/basic/plot_18.png b/msigdb_gobp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..f6236ac40f659c42976ab9eac0574e50186749f5 --- /dev/null +++ b/msigdb_gobp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:25176691c46afe31542aa46c304d59b57262ea73bbb9448ebf2131468606d6ae +size 147300 diff --git a/msigdb_gobp/basic/plot_19.png b/msigdb_gobp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..777845ef2fdecf78a57049814750e4bfb73b27ab --- /dev/null +++ b/msigdb_gobp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fee03d3ca0d8cd8d47df7133838a0240182c258196eabe998cb80625075ca084 +size 137117 diff --git a/msigdb_gobp/basic/plot_2.png b/msigdb_gobp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..2b2fec89ba1910238544bff856c56ec5d1e33e6f --- /dev/null +++ b/msigdb_gobp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:454a2c78837a859254868ee21b973b77aa3615c770739ce1b23d1e86cabada7f +size 146282 diff --git a/msigdb_gobp/basic/plot_20.png b/msigdb_gobp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..ecf8b319cecbadcb298081c7b9ea34e7242f2b34 --- /dev/null +++ b/msigdb_gobp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0972d56db253cd1816382fb5ae3e596437a8e719bfeca5a7cccf1906924f63d1 +size 137303 diff --git a/msigdb_gobp/basic/plot_21.png b/msigdb_gobp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..c1e56a15b8b4cd3a6de34844b2f01bf6d6949f4b --- /dev/null +++ b/msigdb_gobp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b12f2204fdaaa99fed7919f8cbc2b055d676d68512d0845eecd6813754e51415 +size 135036 diff --git a/msigdb_gobp/basic/plot_22.png b/msigdb_gobp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..177cff5eae161404dc3136e95d1f6adbe534c483 --- /dev/null +++ b/msigdb_gobp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:956829d929b96a122ab87c3b2092b244a4e689effbfe62e96cfcb31372c6fbf2 +size 144662 diff --git a/msigdb_gobp/basic/plot_23.png b/msigdb_gobp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..7e54ff7e55eee9e37ea5048223f1cd6db4409425 --- /dev/null +++ b/msigdb_gobp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc9cb9b9863db0f225c8374a244bbf9e1bdc04ffbf1bdc2a70410f95f8d0956b +size 141803 diff --git a/msigdb_gobp/basic/plot_24.png b/msigdb_gobp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..0baf77a4b9c12b436a4535935809116fafaabd14 --- /dev/null +++ b/msigdb_gobp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1be97dc9cc57ac69a23eeff3df0e23d40672c238bbd8d6f49ff9b031dd4bdfd +size 140561 diff --git a/msigdb_gobp/basic/plot_25.png b/msigdb_gobp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..69405f21c404c806684c704841b085903a1b9c11 --- /dev/null +++ b/msigdb_gobp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13bfa75db62d664666959d44c47f1074accfff75507366b0b2f036de14bed7ef +size 137713 diff --git a/msigdb_gobp/basic/plot_26.png b/msigdb_gobp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..57f1c0b49be89cfe65344a91181209aa67063987 --- /dev/null +++ b/msigdb_gobp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e449eef5626d236e23cbcecd2cad06f70a9b6cd2e1e3d0029e58aa08adbea546 +size 145875 diff --git a/msigdb_gobp/basic/plot_27.png b/msigdb_gobp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..095f71e5105ab92e2d93b2a1c620310ba09afb02 --- /dev/null +++ b/msigdb_gobp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b8657bb6feac9c4b2bc082e12f386df7010e33a4c11f814ef56089efc3d94a3 +size 140476 diff --git a/msigdb_gobp/basic/plot_28.png b/msigdb_gobp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..a92ad26352b0e085a74e7bda74dd489e6a0dc789 --- /dev/null +++ b/msigdb_gobp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb7e6da43f3d6e0380c75154786b4fe3d149800d5b74a3bb3953572e63d3233f +size 141243 diff --git a/msigdb_gobp/basic/plot_29.png b/msigdb_gobp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..b99bdb1f9c53e588feffaf29990b2c17029d9bc4 --- /dev/null +++ b/msigdb_gobp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b85408937014a523dc45629af6ca8d5f4f1e033f02e42d37ce08d12e872fa861 +size 140624 diff --git a/msigdb_gobp/basic/plot_3.png b/msigdb_gobp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..40d04efc9863f6e744167ec699fd2e40e611a7e8 --- /dev/null +++ b/msigdb_gobp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84d098dbebc1265e15bb73d231bb77e4ecd459d3d33cfa407500e2c140199796 +size 136513 diff --git a/msigdb_gobp/basic/plot_30.png b/msigdb_gobp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..0f9c4b6f996539c4e94ea237e028c841c2cb72b4 --- /dev/null +++ b/msigdb_gobp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f1585b6ee3f380d6caafe209b8b86bfe5ed030c44d0086c45323b9e557a5bf58 +size 128825 diff --git a/msigdb_gobp/basic/plot_31.png b/msigdb_gobp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..5b711bb1cf295905a18daaef28db8e9b87ea9a52 --- /dev/null +++ b/msigdb_gobp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6be2c3b98bffd2a30e0774aa563cc831d0318b79900cd32eb4ffdb7c5f7c036b +size 136722 diff --git a/msigdb_gobp/basic/plot_32.png b/msigdb_gobp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..afe1f5b7e786562761c46f6417669a7123878f18 --- /dev/null +++ b/msigdb_gobp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9305c1b36cd6c3b1d4886c309e06bdc776929acaf8634522d822c77fbfadeaff +size 138009 diff --git a/msigdb_gobp/basic/plot_33.png b/msigdb_gobp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..2e16559257f46957884a740385ced4c272770486 --- /dev/null +++ b/msigdb_gobp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8602a0235b98711ccafa5f823d8d22ff8095ffda57d83ac50085b9144cfff2f2 +size 145947 diff --git a/msigdb_gobp/basic/plot_34.png b/msigdb_gobp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..72f3f1671931914e7b17e1eb184ff5661ce28a2a --- /dev/null +++ b/msigdb_gobp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99754edabed54385e0a1a9be21b108108b687572dbaf32e81a86880beff6a1cc +size 143160 diff --git a/msigdb_gobp/basic/plot_35.png b/msigdb_gobp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..4b332e79759745add5af9c4f8a81bc4436f0b3b1 --- /dev/null +++ b/msigdb_gobp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:573847cc0143e9997643be89a13e9871dc48deba79632cf0b39884bfdc1a09c6 +size 128435 diff --git a/msigdb_gobp/basic/plot_36.png b/msigdb_gobp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..76ec67b184e06419bc297df7ced1f0f28f177f57 --- /dev/null +++ b/msigdb_gobp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dee7ab219142cf10484a8fb30969e7b32b9207f7cacb30671839afc777a60888 +size 143431 diff --git a/msigdb_gobp/basic/plot_37.png b/msigdb_gobp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..f6bccc59a3c3ae469c5178abeb6bc348c7720469 --- /dev/null +++ b/msigdb_gobp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ef707584dd340cc4655bb6cf51f7961aebdd1bda64b64dffa534109a0f0d55a +size 142399 diff --git a/msigdb_gobp/basic/plot_38.png b/msigdb_gobp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..7455d2b856936726397858ba720245577f90e5d9 --- /dev/null +++ b/msigdb_gobp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a7b8a3a2e9025b673064ca0adf58ba7abfc623ba3caf3d279a1fd7594709a584 +size 141735 diff --git a/msigdb_gobp/basic/plot_39.png b/msigdb_gobp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..d466151f546a1704778a6a1dc8c20da51d7d7f2c --- /dev/null +++ b/msigdb_gobp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b034d4cb2db7c38e1fa83fe7946cda1e42f0227611c7b1761ca8c1722503e97 +size 141117 diff --git a/msigdb_gobp/basic/plot_4.png b/msigdb_gobp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bde216f354745e013f79cfd71d4931849ca17a8a --- /dev/null +++ b/msigdb_gobp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c2e41a6d02a2853488599e170e41cba9ce95a8f53e88351d8b2b575d739dea4 +size 143776 diff --git a/msigdb_gobp/basic/plot_40.png b/msigdb_gobp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..40d4fa2166eb55154dc391f26641cce3858b20d8 --- /dev/null +++ b/msigdb_gobp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2081920d9d4fd07bb9b3ba81bb022ea2b7039ee8fd3cbc726d7af8d10f74763d +size 140016 diff --git a/msigdb_gobp/basic/plot_41.png b/msigdb_gobp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..f4dd043c58cef1c5d256fc90723feee04445e3d5 --- /dev/null +++ b/msigdb_gobp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:143c40fed8ba062632004047e9c7c8196907d5d9786833f6e44465d33b111749 +size 142028 diff --git a/msigdb_gobp/basic/plot_42.png b/msigdb_gobp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..646f80bffb3aef8b4bac44717f25ab1bba87e18a --- /dev/null +++ b/msigdb_gobp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:232a6bfa00276f1a2d87544871f21d39af830d57111c7584771a0a6895ef8bee +size 136481 diff --git a/msigdb_gobp/basic/plot_43.png b/msigdb_gobp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..97fb5601b0623b7cadb689a85a7cbe7cd540b5c8 --- /dev/null +++ b/msigdb_gobp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d1821d9e51427742b1c7aa1fbf6efcda8bf4e2a2cf069d846ffd3ac68c834ace +size 144435 diff --git a/msigdb_gobp/basic/plot_44.png b/msigdb_gobp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..d418ea262df372a4bd7a46b96f8e1b4b84911ab1 --- /dev/null +++ b/msigdb_gobp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd3381f5bf419702fb8fcf0a5131391e65efebc03c0197f9f28ae772293ff099 +size 141406 diff --git a/msigdb_gobp/basic/plot_45.png b/msigdb_gobp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..b16585a349e1de94ad01d1a33c4712b4778f5d75 --- /dev/null +++ b/msigdb_gobp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b812bfb20ae962c8cec369441c8e91b2f948a08725f6894ecb2dd86d227258e9 +size 130623 diff --git a/msigdb_gobp/basic/plot_46.png b/msigdb_gobp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..6be80754ad106a09936428bf7e3aff410aadf200 --- /dev/null +++ b/msigdb_gobp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:276220ca3bfd20e75871418a2e83df7142b6ae6379c870c74574a7cc0a545395 +size 148394 diff --git a/msigdb_gobp/basic/plot_47.png b/msigdb_gobp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..d9a187afd4f207164998f000c57efb3b7722cfac --- /dev/null +++ b/msigdb_gobp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dfc77ce8784fb8aab8dddb92e17d7879974a1651248fa2979ed1c7e61005f9d8 +size 140936 diff --git a/msigdb_gobp/basic/plot_48.png b/msigdb_gobp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..45638ce4b0db5bab1a8a3dccd030f0111b6328f2 --- /dev/null +++ b/msigdb_gobp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fccac64fc6caf1ab8b1b45a695ed66fdef90ffc22310e6780cbdefe97a2d02e +size 144295 diff --git a/msigdb_gobp/basic/plot_49.png b/msigdb_gobp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..31b3b805072128587ae0fec1fe542b51c8e98b56 --- /dev/null +++ b/msigdb_gobp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a12d59ce2aa541855266a19e2584f1c4f50cf9f8d05e49b1374192c88e1fa0e0 +size 136067 diff --git a/msigdb_gobp/basic/plot_5.png b/msigdb_gobp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..3938f73a10646cb5623150cc1fb4809df5845422 --- /dev/null +++ b/msigdb_gobp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b158a577b797f8bf335e258280dd75c982cdf3530a4cca1830e0e64591134da +size 143977 diff --git a/msigdb_gobp/basic/plot_6.png b/msigdb_gobp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..eb7fdd818a481f87cc579d5b770cb75c6ad2df47 --- /dev/null +++ b/msigdb_gobp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a34ae7c750ba2ee6f19062e5d3118f1d66a0154c8b785704f01f7cf50658f069 +size 144813 diff --git a/msigdb_gobp/basic/plot_7.png b/msigdb_gobp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..5d496e60193a2791ec9211f3ea84b08c191b0c51 --- /dev/null +++ b/msigdb_gobp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b2726b88413d2702d3b567500a9251294e0f273fbe4e7aed8927df8a9b2f866 +size 141528 diff --git a/msigdb_gobp/basic/plot_8.png b/msigdb_gobp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..5f03cd2834002b3d5c3d4948057a28f5d8372e07 --- /dev/null +++ b/msigdb_gobp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:edee6dcaae1883475fa9d8f1d894f94579149a2ecdd464f571ce39bee21634cc +size 145749 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..eaf97968e6ab80d2750bbe494d56c190c351056a --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10a1490bb226d10aa2d2c2e252e9c40336fd2177529911154d8fac79419a163a +size 145364 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d4e51488ed7b51a0d69207123ee4b03bb85e86c9 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21fce4f5829b7241e7593565bc046e505139e641b078da154fd0ccd6a532fc41 +size 700454 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d0d7501a2769d2eb96cdab852e3875be308c2925 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,77 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Mitochondrion organization 49 180 4.331723190291285 1.479468712695109e-05 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 0.0007473083540838 0.000828657731491 6.480870627166138e-06 6.981709690754751e-06 +Transmembrane transport 31 199 4.133637948016036 3.570658131368809e-05 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 2.5693261508128997e-05 0.0011042222879992 0.0002006312644223 0.0228187338159456 +Mitochondrial transmembrane transport 10 47 3.939501851885008 8.165097186463299e-05 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 4.165927418504747e-05 0.0001514529355526 5.918077284044873e-06 1.2912647045240088e-05 +Mitochondrial transport 21 78 3.7549110205911465 0.0001734030697504 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 0.0001160257405869 0.0011154485009446 0.0002318296970005 0.0002067847104192 +Protein localization to mitochondrion 11 53 3.600837851541796 0.000317193359318 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 0.0014960741415954 0.019444978609395 0.0002802094112185 0.0022209553583206 +Protein targeting to mitochondrion 9 43 3.547664135308422 0.0003886634979157 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 0.0006962305099777 0.0097621950354221 0.0012809712291409 0.0035274529804402 +Anion transmembrane transport 7 39 3.294924970322477 0.0009844796154894 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0001552927253207 0.0006744002481248 0.0015592799821653 0.0463253080789513 +Protein targeting 22 110 3.096993543338507 0.0019549413185024 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 0.0009658472301422 0.0098872250066504 0.001158899500604 0.0012183169198357 +Mitochondrial membrane organization 11 41 2.966996134757395 0.0030072473961515 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.0097225551321659 0.0633283793886803 0.0022397853800219 0.0023542271973535 +Protein localization to organelle 65 325 2.876601833202104 0.0040198246713023 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 0.0176993701911854 0.1580673135586307 0.0001794607861363 0.0004680763281557 +Carboxylic acid transport 5 28 2.787250096792732 0.0053157436470083 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0842284999560231 0.0177198518564191 0.0420396019683425 0.4053188077741594 +Protein transmembrane import into intracellular organelle 4 13 2.725510039126042 0.0064202223978901 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0083336110644575 0.032784445092202 0.0056128198685199 0.0139902560164694 +Protein transmembrane transport 4 24 2.7135167906923363 0.0066573194384305 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.001829927485586 0.0138699265420804 0.008923404115777 0.043045103354355 +Ion transport 40 195 2.630611873516955 0.0085231312267721 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 0.0077089578712886 0.0166092681319762 0.002907801834208 0.0536515655970312 +Mitochondrial gene expression 12 58 2.593601491170722 0.0094976502527981 16.449029126213592 56.182038834951456 -0.2404951074706974 0.6120234675741325 10.427271191174482 6.788294302140445 1.0133100522202234 0.3376694104983603 0.3859195782313845 0.0004784923631454 0.0009870444122445 0.0017191594080314 +Protein import into mitochondrial matrix 2 8 2.547756189178414 0.0108418213988137 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0021019285577768 0.0086772133501052 0.0051503840765812 0.0338099842169397 +Anion transport 9 63 2.541305919142442 0.01104392415665 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0002903600066078 0.0006188538425275 0.0094183436704878 0.1102601149267901 +Organic acid transport 6 41 2.5220272062692044 0.0116680683546335 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.1312404960008572 0.041475104793022 0.0488236457953868 0.2246827082089517 +N terminal protein amino acid modification 6 11 2.518654861481429 0.0117804067029134 2.45873786407767 8.439320388349515 0.5804938412353885 0.4249038973587519 1.7696871423418874 1.4824892226959214 1.0345977331938565 0.310740936912418 1.0 0.2202973788945578 0.0033024410276518 0.0001833997890783 +Porphyrin containing compound metabolic process 4 17 2.481621978297297 0.0130785939175184 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0112335965286378 0.00032146493584 0.001435579094649 0.0063226090272968 +Ion transmembrane transport 21 146 2.4735306252811995 0.0133785337032623 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 0.0046085411601665 0.0295697963442294 0.0036340316587734 0.0587657098138924 +Intracellular protein transmembrane transport 3 21 2.399574602645976 0.0164141347259825 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0181544170345696 0.0681167311872175 0.0230341265569123 0.0664883963333954 +Leukocyte homeostasis 3 10 2.373015871592008 0.0176435057493455 3.4029126213592233 12.177184466019416 0.5028432712633871 0.4794963594230453 1.9872875748080177 2.4917658251002113 0.9479568975066928 0.3126900449378977 0.214048603403005 0.0874698992517949 0.0367529115341812 0.2469963169810251 +Establishment of protein localization to mitochondrial membrane 4 14 2.3690609453215443 0.0178333145646352 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 0.0067836126853756 0.0269433955752302 0.0038040834633598 0.0089325963600969 +Mononuclear cell differentiation 11 51 2.367314330354821 0.017917707844681 9.111650485436892 45.05825242718446 0.1366745299088765 0.6662710348554396 5.006031332610922 5.303553018108913 0.7143498771214317 0.2995144284800984 0.2368786634696672 0.1246031715103092 0.1153673676307535 0.2756351624319578 +Protein insertion into mitochondrial inner membrane 2 5 2.348594196133625 0.0188444320376524 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 0.0539630923046902 0.1084298440104649 0.00262770885776 0.0182159139614431 +Homeostasis of number of cells 19 63 2.3216531608931854 0.0202516189345982 12.053398058252426 60.39563106796116 -0.223566006191355 0.6634135713369319 5.7901878087819485 5.813967141474191 0.6989753775852942 0.300187792641174 0.0546724895043807 0.1026258148472988 0.0846349217101784 0.0728138249394277 +Apoptotic cell clearance 3 8 2.316751111758536 0.0205172935592345 1.4150485436893203 8.16747572815534 0.7343377868729896 0.4133364508748849 1.6160802235364573 1.40166698151907 0.89060803593971 0.2988103853625464 0.0883440144706526 0.1741653971767485 0.0834574734746242 0.0144964406909979 +Protein insertion into membrane 9 24 2.3065391972484237 0.0210805225439105 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 0.0229764784753464 0.0846123699035222 0.0075944976014186 0.0030132274761459 +Tetrapyrrole metabolic process 4 20 2.28706515232549 0.0221920205226442 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0173981049202063 0.0007806859566535 0.0040251974639471 0.0190396454378568 +Protein import 7 84 2.263531996252061 0.0236029145289318 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 0.0087577744653219 0.0881474282917187 0.028253689956658 0.0916106359914445 +Lymphocyte apoptotic process 2 14 2.2537187972977617 0.024213864058602 2.9514563106796117 15.24757281553398 0.5373359856012997 0.4921541780831517 2.125337852190875 2.356949841506499 0.8748252580005311 0.2965231483725897 0.172880472870427 0.0578012116494448 0.0764078368784309 0.3228304985102302 +Organic acid transmembrane transport 4 25 2.2531046855295496 0.0242525491162335 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0523670081739014 0.0405305960068218 0.0444212272681039 0.1944132869758354 +Protein depalmitoylation 1 5 2.235815437974719 0.0253638632609995 1.3203883495145632 4.468446601941747 0.9114659728007516 0.274733419943775 1.0188856680336909 0.6320520706114182 1.1467191069327447 0.2583665413440971 0.0451714964804377 0.0912026913027489 0.0231366382468947 0.0823369674942117 +Macromolecule depalmitoylation 1 5 2.235815437974719 0.0253638632609995 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0539630923046902 0.1084298440104649 0.0328731354880699 0.113339965404402 +Positive regulation of protein localization to early endosome 3 5 2.23557790995846 0.0253794329253393 2.296116504854369 4.031553398058253 0.1272781464176911 0.4887956323086924 1.218659324640572 0.7250540753607216 1.0227335460175853 0.3086652690655555 1.0 0.0647424502180396 1.1110147517061663e-05 0.0001735559058557 +Regulation of protein localization to endosome 3 5 2.23557790995846 0.0253794329253393 2.2936893203883497 4.174757281553398 0.1076095823178649 0.4867146243559223 1.241928886768022 0.8581667575746583 1.026964828557357 0.3094893088919009 1.0 0.0998570540504815 9.701143498590324e-05 0.0013990642028563 +Cell recognition 7 23 2.2274386315758647 0.0259179729690426 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.0027399214461653 0.0201824597439383 0.0034676048515423 0.0091218528537202 +Establishment of protein localization to organelle 30 175 2.216482045650364 0.0266585061755035 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 0.0011427434662643 0.0534169975731404 0.0132245390688013 0.0432590942041547 +Cellular response to cadmium ion 1 5 2.205588537421416 0.0274128223879974 0.9466019417475728 4.754854368932039 0.7346630274062432 0.4142129684279865 1.120013482406765 1.5170873755341794 0.9297582928234152 0.2900223727485326 0.0030359610091143 0.0124120710913681 0.0693365470158766 0.2179847922025966 +Mitochondrial respiratory chain complex assembly 8 35 2.203658522960482 0.0275483681846857 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.0657516499382864 0.0017133517402868 0.0229258137019905 0.0128795525515119 +Ether metabolic process 1 7 2.2036361089757106 0.0275499457188699 2.3009708737864076 8.116504854368932 0.6936598083237113 0.3993528168351505 1.8983127483146185 1.066260782267489 0.9725930071190376 0.2989456029254039 0.0798652174269664 0.1581956798045988 0.0693365470158766 0.2179847922025966 +Membrane lipid biosynthetic process 7 18 2.181112536121108 0.0291750938409363 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0547194429686685 0.183361016235644 0.3195580599455 0.5716036991382609 +Pyridine containing compound catabolic process 1 5 2.169881924823237 0.0300157919632733 0.7402912621359223 3.512135922330097 0.7508771334364693 0.4231264060447552 0.8802183713066808 0.9016426761781536 0.947958671209911 0.2996321046725578 1.0 0.0557540441617295 0.1368589802283267 0.0312108672695238 +Diol biosynthetic process 1 7 2.1691192619416446 0.0300736306820081 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0015706319822673 0.0065261066260236 0.0382400085743442 0.1297945989547683 +Diol metabolic process 1 7 2.1691192619416446 0.0300736306820081 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0023951619417497 0.0098557770733155 0.0561137872346343 0.1818418904091173 +Regulation of golgi organization 6 10 2.1442686525979364 0.0320113670213924 1.944174757281553 7.259708737864078 0.4938360404065116 0.4881247097287292 1.6646787638867808 1.6274430217223506 0.8799056721214452 0.3073140855538377 1.0 1.0 0.0693365470158766 0.0098879726868235 +Regulation of macroautophagy 18 59 2.1385168850039245 0.0324748152068095 12.53883495145631 54.54368932038835 0.6601926076755246 0.5184966676512008 5.17189441564166 7.149617002477752 0.982640144191414 0.3711017134042489 0.0032853402084552 0.0387349726479144 0.0161335998015439 0.0303231419933257 +Inner mitochondrial membrane organization 6 17 2.12985171998179 0.0331838571596279 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.1573929974646098 0.2983459236646945 0.0018532910789756 0.0018029983207632 +Positive regulation of mitochondrial translation 1 6 2.1050086894360813 0.0352905516772108 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0670021260054199 0.0086772133501052 0.0498779046475234 0.1641299211995837 +N terminal protein amino acid acetylation 3 7 2.1016353963870813 0.0355852267127634 1.7621359223300972 5.29126213592233 0.468170205145664 0.4621753504993651 1.4369342030361782 1.0061082182443093 0.9803510996484076 0.3117526403347991 1.0 1.0 0.0498779046475234 0.0049531384619904 +Leukocyte differentiation 14 71 2.0999084521354168 0.0357368951083656 13.259708737864075 62.82281553398058 0.2230074329146526 0.6311707774623282 5.891661699815195 7.755058720737631 0.8147397072079771 0.3290680435049292 0.3497290849553038 0.249185970661988 0.1999556132726856 0.3223655981077151 +Sphingoid metabolic process 2 5 2.0981363709179317 0.0358931004625961 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0451714964804377 0.0912026913027489 0.2175647207167039 0.0823369674942117 +Excretion 1 7 2.098030179893885 0.0359024794473277 1.269417475728155 5.201456310679611 0.6776908500633984 0.3886507914896875 1.1481249595760017 0.8622041158633096 0.9714806682442636 0.2826040335002768 0.0841142186818086 0.0137871179019738 0.0762921742488627 0.236286730772413 +Modification of synaptic structure 1 8 2.080465861678697 0.0374828237312185 1.9902912621359223 8.087378640776699 0.8554193794108192 0.3851394739224027 1.562579058231813 0.6625457832358376 0.856660193170285 0.2984698193580089 0.0841142186818086 0.1662183776826317 0.0762921742488627 0.236286730772413 +Neuron apoptotic process 8 53 2.0648511987012497 0.0389370817908842 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.1485717214577993 0.4126058738515607 0.0274278527807438 0.2957013184485878 +T cell apoptotic process 1 10 2.050716100566229 0.0402946021001444 2.145631067961165 10.701456310679612 0.7461760702030203 0.3927793123326719 1.654107960636956 1.7995948345334825 0.9259723405034824 0.2877845742037807 0.1174219198717282 0.2277340705622599 0.1383652025719425 0.3817623273994432 +T cell differentiation 7 30 2.0419155160590283 0.0411599123900108 5.021844660194175 25.37378640776699 0.4350228719786409 0.5180951440553598 2.967789621588004 3.0760730597535333 0.9025381406717272 0.3196787714458526 0.1070124290166615 0.3202129502459803 0.0735170949016835 0.2373706928122872 +T cell activation 12 61 2.039737204952994 0.0413765071819687 11.87135922330097 56.20145631067961 0.3819132128629459 0.6116920144187052 4.9576316669096165 6.2667792486255545 0.7788461990309965 0.3330306669624288 0.2832173853246781 0.6424784665752556 0.1026108480108814 0.2227294085387225 +Protein localization to endoplasmic reticulum 12 32 2.038918065520257 0.0414582055846504 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0282648516431577 0.1021730546658088 0.1596086760652474 0.0200998155918958 +Positive regulation of translation 13 55 2.034317168958338 0.0419196272187449 14.00485436893204 59.04854368932039 0.2226635785383083 0.671926467094376 6.74788537377648 3.7113801394297217 0.7891314904677239 0.3244977763908461 0.3972821770368059 0.0853490882644616 0.0489196207839397 0.0841305446551627 +Localization within membrane 37 177 2.0275407236377823 0.0426071441028155 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.022447480281961 0.0877417559983802 0.045088458803862 0.0068852668694697 +Glycosyl compound biosynthetic process 3 8 2.017870788129195 0.0436047200898528 1.7621359223300972 6.927184466019417 0.7674599123201137 0.3848892158216302 1.5816678247150102 0.68587612099484 1.0539983320068638 0.3161304697180149 1.0 0.1500965904253892 0.062605312422627 0.0079931710216612 +Folic acid metabolic process 1 8 2.0175443829922184 0.0436387342213939 1.91747572815534 7.140776699029126 1.2977645388348351 0.249592124826322 1.215987926650751 0.8615786924829095 0.8405378716662024 0.2600707347072601 0.0018270290105774 0.0075668597133861 0.0439142352380576 0.1467539296032722 +Stem cell proliferation 5 12 2.0165170364286102 0.0437459385842116 2.371359223300971 11.266990291262136 0.2871855378077091 0.5682911182372676 1.937232310875086 1.1262868238661403 0.7998448963266326 0.2886312572020901 0.0159273139692264 0.0603249601752956 0.2707185745648809 0.0520328360234653 +Mitochondrial rna metabolic process 11 28 2.0159524772577178 0.0438049453781521 9.70388349514563 27.32281553398058 -0.4093497868392177 0.5922287818171686 5.150613543056959 2.9436724693397855 0.814967382754061 0.3125468569375974 1.0 0.0105950719619242 0.0284489140367958 0.0281454476703931 +Lymphocyte homeostasis 4 7 2.015201250937062 0.0438835665195074 2.6140776699029127 9.157766990291265 0.5015073935560286 0.4550844260550281 1.7177248086463766 2.3424870328572864 0.9807186663047854 0.3016646201978763 0.1612912678811883 0.0504636045608497 0.063688713570506 0.2822516950414785 +Membrane organization 64 216 2.0057373549532387 0.0448842774986126 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 0.0100566935145434 0.1301826712620676 0.0004586892059552 0.0001725163988398 +Golgi organization 22 55 1.9931958634433544 0.0462400039022179 16.643203883495147 56.43689320388349 0.631232933893225 0.5683910993217528 6.594450257690171 8.413373430660274 1.0599635722797485 0.3790700076783576 1.0 1.0 0.3536157347104673 0.0073154070839396 +Regulation of nervous system process 2 13 1.991763052030274 0.0463970619586124 2.6941747572815533 11.186893203883496 0.709685710886722 0.4267375683332639 1.6891041598029932 2.2483053074671338 0.9287991925104498 0.3050882814355576 0.0238262610416272 0.0874698992517949 0.1312000588255236 0.4687829092097882 +Nucleoside salvage 2 6 1.9894469937134545 0.046651886987725 1.194174757281553 5.087378640776699 0.7525597745497481 0.4015392353821809 1.3351720912111715 0.2990858602087254 0.9698061350109142 0.3038187137036782 1.0 0.073646168181401 0.0148625463558957 0.0053637976870067 +Purine nucleoside biosynthetic process 2 6 1.9894469937134545 0.046651886987725 1.4611650485436891 5.742718446601942 0.8935109670252933 0.3592786141720023 1.2698698816998135 0.508968486969168 1.0201063575252725 0.3098922359465458 1.0 0.0912026913027489 0.0231366382468947 0.010684483318579 +Purine ribonucleoside salvage 2 6 1.9894469937134545 0.046651886987725 1.194174757281553 5.087378640776699 0.7525597745497481 0.4015392353821809 1.3351720912111715 0.2990858602087254 0.9698061350109142 0.3038187137036782 1.0 0.0557540441617295 0.0082211090226218 0.002061539822863 +Regulation of mitochondrial gene expression 3 9 1.978005650111526 0.0479280692624759 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.1174219198717282 0.0269433955752302 0.1383652025719425 0.3817623273994432 +Mitochondrial genome maintenance 3 9 1.9739025733752464 0.0483928221099996 2.5970873786407767 9.099514563106796 0.4306784309108238 0.5191675610799616 1.8467476691551616 1.335584580667961 0.8583625990868251 0.3062673449054504 1.0 0.1820374447866984 0.0135296171343662 0.0172333771485565 +Negative regulation of neuron apoptotic process 5 26 1.9718398307742395 0.0486278937940507 5.757281553398058 26.135922330097088 0.5817179538337637 0.4854643114827585 2.727835727399863 2.4377633537168184 0.9011837787919588 0.3153742372034477 0.0571089185161482 0.1902313934880583 0.0528572065128901 0.2254780651450759 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..23d747baef11fcec4596235e401ff15efb99eb0e --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 6526, + "title": "Average number of proteins per term", + "value": 20.252988047808763 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5037bacccdfa5c69b211b56007a7daa5c48be79d --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..aab069db8e21ab450be5248d469b6c017ecdc121 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1915 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrion organization 0.4365593293353129 4.331723190291285 1.479468712695109e-05 0.0920362666400062 0.0103213712308243 180 O60830,Q9UDX5,Q09472,Q99595,O43678,O95376,O43615,P49257,Q9Y5J9,O43676,P51572,P04062,P21796,Q9NS69,Q04837,Q99623,P45880,Q9P0J0,O75323,Q8N4H5,P50542,Q5T9A4,P51970,Q9NVH1,Q9NVA1,O60313,O75153,Q96TA2,P51530,Q9Y5P4,P27695,Q10713,Q7KZI7,Q96A26,O75306,Q6DKK2,O14737,Q00059,Q9Y6C9,O00429,Q9H061,Q9BSK2,Q86Y39,Q9UJZ1,Q9Y5L4,Q9NX63,P12235,Q13505,Q9NVI7 49 +Transmembrane transport 0.4198988778010817 4.133637948016036 3.570658131368809e-05 0.2078664755865157 0.0103213712308243 199 O60830,Q99595,O43615,Q70HW3,Q9H2D1,O75964,P04062,P21796,Q9NS69,O75381,Q9UHG3,Q99996,P08183,Q8WTV0,Q12959,P45880,Q9HD20,P27695,Q96PU5,Q9UBX3,Q9UDW1,Q06481,Q9BSK2,Q6P4A7,P18859,P53007,P14854,P12235,Q8NB49,P38435,P53985 31 +Mitochondrial transmembrane transport 0.6461867638457107 3.939501851885008 8.165097186463299e-05 0.4130854248549716 0.0103213712308243 47 O60830,P18859,Q99595,O43615,P53007,Q9H2D1,O75964,P21796,Q9BSK2,Q6P4A7 10 +Mitochondrial transport 0.5312039382341948 3.7549110205911465 0.0001734030697504 0.6775239981738034 0.0103819122311138 78 O60830,Q99595,O95376,O43615,Q9Y5J9,P51572,O75964,Q9NS69,P45880,Q9P0J0,Q8N4H5,Q10713,O14737,P06576,Q9UBX3,P56134,Q9UJZ1,P18859,Q9Y5L4,P23786,P12235 21 +Protein localization to mitochondrion 0.577635046599025 3.600837851541796 0.000317193359318 0.8738561337927574 0.0125444550753216 53 O60830,Q9Y5L4,Q99595,O43615,Q9P0J0,Q8N4H5,Q9Y5J9,Q9Y6C9,O00429,Q9NS69,Q10713 11 +Protein targeting to mitochondrion 0.6184141488578562 3.547664135308422 0.0003886634979157 0.9208896069605182 0.0133495683547281 43 O60830,Q9Y5L4,Q99595,O43615,Q9P0J0,Q8N4H5,Q9Y5J9,Q9NS69,Q10713 9 +Chemokine c x c motif ligand 2 production 0.9680501642281264 3.3042224609351765 0.0009524022478863 0.9980074473426244 0.0229220582016531 2 P14174 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.9680501642281264 3.3042224609351765 0.0009524022478863 0.9980074473426244 0.0229220582016531 2 P14174 1 +Anion transmembrane transport 0.6090475106539057 3.2949249703224774 0.0009844796154894 0.9983841247971084 0.022945407038157 39 P45880,P53007,Q9H2D1,Q9UBX3,P21796,Q9UHG3,P08183 7 +Negative regulation of p38mapk cascade 0.9501343684681998 3.226600905147764 0.0012527005314288 0.9997198676643994 0.0261188337645347 2 Q12959 1 +Aminophospholipid transport 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.999990628542198 0.0300456565719267 2 Q14108 1 +Protein targeting 0.4553859014913778 3.096993543338507 0.0019549413185024 0.9999971563833284 0.0314235148880474 110 O60830,Q99595,O43615,P09132,Q9Y5J9,P51572,O75381,Q9NS69,P33908,Q14108,Q9P0J0,Q8N4H5,P50542,P27695,Q10713,O43681,O14737,Q8IWJ2,O60725,Q9Y5L4,P51159,Q9UJ41 22 +Positive regulation of protein neddylation 0.9199761122723128 3.094280050594453 0.0019729116044051 0.999997471637497 0.0316344499517151 2 Q9BTE7 1 +Intestinal hexose absorption 0.9184831292923228 3.087674649260433 0.0020172919492096 0.9999981085064744 0.0321093835622977 2 P15311 1 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.9157957599283256 3.075771750825459 0.002099585034138 0.999998895697056 0.0327796457722134 2 P43490 1 +Positive regulation of lipopolysaccharide mediated signaling pathway 0.8972827709763997 2.9933107148356943 0.0027596863393288 0.9999999852881044 0.0396573644028083 2 P14174 1 +Proton transporting v type atpase complex assembly 0.8928038220364192 2.973238043481636 0.0029467581933413 0.9999999956753456 0.0409926508777631 2 Q92544 1 +Vacuolar proton transporting v type atpase complex assembly 0.8928038220364192 2.973238043481636 0.0029467581933413 0.9999999956753456 0.0409926508777631 2 Q92544 1 +Mitochondrial membrane organization 0.5570361475878062 2.966996134757395 0.0030072473961515 0.9999999970892786 0.0414911131232241 41 P45880,Q9Y5L4,Q9P0J0,P50542,O14737,Q9Y5J9,Q9NVH1,O60313,P12235,Q9NS69,Q13505 11 +Negative regulation of mast cell activation 0.8904150492684253 2.962512983865342 0.003051389398998 0.9999999978197164 0.0418348050795408 2 P09601 1 +Negative regulation of mast cell activation involved in immune response 0.8904150492684253 2.962512983865342 0.003051389398998 0.9999999978197164 0.0418348050795408 2 P09601 1 +Negative regulation of mast cell degranulation 0.8904150492684253 2.962512983865342 0.003051389398998 0.9999999978197164 0.0418348050795408 2 P09601 1 +Cholesterol catabolic process 0.8892206628844295 2.9571453212297913 0.0031050174079712 0.9999999984652032 0.0420745077714131 2 Q8WTV0 1 +Recognition of apoptotic cell 0.8889220662884305 2.9558028703706096 0.0031185634162342 0.9999999985954446 0.0420745077714131 2 Q8WTV0 1 +Sphingolipid mediated signaling pathway 0.8868318901164445 2.9463997146628964 0.0032149665061569 0.9999999992527866 0.0427308990207335 2 P15311 1 +Positive regulation of clathrin dependent endocytosis 0.8805613616004784 2.918127114091531 0.0035214076647327 0.9999999998995402 0.0449344253509788 2 Q6P3W7 1 +Protein import into peroxisome membrane 0.8796655718124835 2.914080422850564 0.0035673799178623 0.999999999925658 0.0451937473205089 2 P50542 1 +Dedifferentiation 0.8733950432964963 2.885699170119946 0.0039054526224775 0.9999999999918816 0.0473735758629897 2 Q00534 1 +Protein localization to organelle 0.3175978648807858 2.876601833202104 0.0040198246713023 0.9999999999961626 0.0475455590302003 325 O60830,P24390,P67809,Q99595,O43615,Q96BK5,Q15006,P35240,O95376,P09132,Q9Y5J9,Q15648,Q8WUX9,P49257,P83436,Q14789,P51572,P55735,O75381,Q9NS69,P33908,P40855,Q6GQQ9,Q14108,Q7L5D6,Q99623,Q96HY6,Q12959,Q9P0J0,Q8N4H5,P50542,Q13043,P15311,Q9Y5K8,P15927,Q00839,Q96JB5,Q13561,Q10713,O43681,O14737,Q8TDB6,Q9Y6C9,P12270,Q8IWJ2,P49458,O00429,Q9UPT5,Q06481,P17252,Q9UIS9,P35241,P05455,Q9Y5L4,Q9NPI6,Q96EZ8,Q9P0I2,O15344,Q5JTV8,Q9UNF0,Q96A33,P61960,P31483,P26038,Q8N1F7 65 +Regulation of phospholipase a2 activity 0.9452334218764076 2.813059075324185 0.0049072634812024 0.9999999999999886 0.0532858593649366 3 P50897 1 +Carboxylic acid transport 0.6135125798775163 2.787250096792732 0.0053157436470083 0.9999999999999992 0.056315816623988 28 P14174,P53007,Q9H2D1,P07602,Q9UBX3 5 +Thyroid hormone mediated signaling pathway 0.8456255598686 2.758857109754131 0.0058003891268971 1.0 0.0586711202844953 2 P42785 1 +Branching involved in mammary gland duct morphogenesis 0.839653627948641 2.731331291156724 0.0063079027588588 1.0 0.0609857383767597 2 Q15648 1 +Protein transmembrane import into intracellular organelle 0.8062349405439717 2.725510039126042 0.0064202223978901 1.0 0.0617970079183354 13 O60830,O75381,Q99595,O43615 4 +Protein transmembrane transport 0.6435048321352 2.7135167906923363 0.0066573194384305 1.0 0.0635170565134466 24 O60830,Q9NS69,Q99595,O43615 4 +Histone h4 r3 methylation 0.8330845028366717 2.7009507647660924 0.0069141573061219 1.0 0.0654888107108158 2 Q99873 1 +Positive regulation of nitric oxide synthase activity 0.916165508566156 2.6913345327259792 0.0071166791999122 1.0 0.0666072213274201 3 Q8WTV0 1 +Negative regulation of ire1 mediated unfolded protein response 0.8256195879366961 2.666297164649489 0.0076691869651013 1.0 0.0699987610269248 2 Q96HY6 1 +Attachment of gpi anchor to protein 0.8208420424007159 2.644045935484139 0.0081921537742817 1.0 0.0711877437163283 2 Q92643 1 +Ion transport 0.3411067851723026 2.630611873516955 0.0085231312267721 1.0 0.0731839655242711 195 Q70HW3,Q9H2D1,Q93034,O75964,P50570,P21796,Q9UHG3,Q99996,P08183,Q12959,P45880,P07602,Q9HD20,Q9HC21,Q9Y5P4,P27695,O15173,P14174,O43681,P24941,Q96PU5,P06576,Q9UKS6,Q9UBX3,Q9UDW1,P56134,O00429,Q8NE01,P17252,Q6P4A7,Q9UJZ1,Q9UM00,P18859,P53007,Q9UNH7,P14854,P12235,Q8NB49,P53985,P16615 40 +Dttp metabolic process 0.9004551974444475 2.624823437495021 0.0086693909941684 1.0 0.0740529393035904 3 Q9H773 1 +Negative regulation of actin nucleation 0.8112869513287595 2.5993722713954885 0.0093394428064537 1.0 0.0773527895906949 2 Q9BR76 1 +Negative regulation of arp2 3 complex mediated actin nucleation 0.8112869513287595 2.5993722713954885 0.0093394428064537 1.0 0.0773527895906949 2 Q9BR76 1 +Mitochondrial gene expression 0.4623906394604011 2.593601491170722 0.0094976502527981 1.0 0.0780625510702275 58 P46199,O95900,O15091,Q00059,Q16540,Q567V2,Q96EY7,Q9BSK2,O75879,Q9BW92,Q9Y3D3,Q969Z0 12 +Calcium ion import into sarcoplasmic reticulum 0.8014332636607824 2.55306289687754 0.0106780211663384 1.0 0.0846716477904308 2 P16615 1 +Phosphagen metabolic process 0.8008360704688 2.550248434660536 0.0107646180325795 1.0 0.0851513906431686 2 P12277 1 +Protein import into mitochondrial matrix 0.8776619624247182 2.547756189178414 0.0108418213988137 1.0 0.0856582644656881 8 O60830,Q99595 2 +Anion transport 0.4498513868639072 2.541305919142442 0.01104392415665 1.0 0.0866257801037235 63 P45880,P14174,P53007,Q9H2D1,P07602,Q9UBX3,P21796,Q9UHG3,P08183 9 +Phosphatidylinositol acyl chain remodeling 0.877005564638047 2.524596066167895 0.0115831341599359 1.0 0.0892793898258235 3 Q96N66 1 +Organic acid transport 0.5063471569606316 2.5220272062692044 0.0116680683546335 1.0 0.0896888269521064 41 P14174,P53007,Q9H2D1,Q9UBX3,P53985,P08183 6 +Negative regulation of cell volume 0.7942669453568205 2.519230206129232 0.0117611734207283 1.0 0.0898751964211868 2 P51790 1 +Regulation of membrane invagination 0.7942669453568041 2.5192302061291523 0.011761173420731 1.0 0.0898751964211868 2 Q06481 1 +Potassium ion export across plasma membrane 0.7942669453568019 2.519230206129139 0.0117611734207314 1.0 0.0898751964211868 2 Q12959 1 +Regulation of potassium ion export across plasma membrane 0.7942669453568019 2.519230206129139 0.0117611734207314 1.0 0.0898751964211868 2 Q12959 1 +N terminal protein amino acid modification 0.808347044880608 2.5186548614814295 0.0117804067029134 1.0 0.089916882038846 11 Q9BV86,P53582,P50579,Q9BXJ9,Q86UY6,P41227 6 +Positive regulation of amyloid beta clearance 0.7888922066288477 2.493770967038902 0.012639407088733 1.0 0.0945762779051734 2 P30533 1 +Vitamin d metabolic process 0.8673053564465657 2.482801634776785 0.0130353654271835 1.0 0.0945762779051734 3 P04062 1 +Porphyrin containing compound metabolic process 0.6899244172485808 2.481621978297297 0.0130785939175184 1.0 0.0945762779051734 17 P53004,P09601,P36551,P30519 4 +Thrombin activated receptor signaling pathway 0.8664874551971283 2.479268662649149 0.0131652100312662 1.0 0.0948301994084366 3 P16949,Q9NWH9 2 +Deoxyribonucleoside triphosphate biosynthetic process 0.8655219420991789 2.475096280292899 0.013320026189145 1.0 0.0954187606041281 3 P55263 1 +Ion transmembrane transport 0.3753137749822498 2.4735306252811995 0.0133785337032623 1.0 0.0957327970915462 146 Q70HW3,Q9H2D1,O75964,P21796,Q9UHG3,Q99996,P08183,Q12959,P45880,Q9HD20,P27695,Q96PU5,Q9UBX3,Q9UDW1,Q6P4A7,P18859,P53007,P14854,P12235,Q8NB49,P53985 21 +Regulation of microvillus length 0.8649093004812196 2.4724477955525836 0.0134191311059983 1.0 0.0958131833673361 3 P15311 1 +Regulation of cell projection size 0.8649093004812196 2.4724477955525836 0.0134191311059983 1.0 0.0958131833673361 3 P15311 1 +Regulation of fertilization 0.7829202747088703 2.465397723267264 0.0136861241359933 1.0 0.0971878630157699 2 Q9NVM9 1 +Schwann cell proliferation 0.8623903191242026 2.461549884579265 0.013833815847797 1.0 0.0981298719812214 3 Q96G23 1 +Amino acid salvage 0.860114688211088 2.4516934291078747 0.0142185743779814 1.0 0.0998716296047987 3 Q13126 1 +L methionine salvage from methylthioadenosine 0.860114688211088 2.4516934291078747 0.0142185743779814 1.0 0.0998716296047987 3 Q13126 1 +Trna pseudouridine synthesis 0.779934308748877 2.4511774706500673 0.0142389729943723 1.0 0.0998716296047987 2 Q9Y606 1 +Hemoglobin metabolic process 0.7769483427888861 2.436934803050609 0.0148123497310377 1.0 0.1027348360766125 2 Q99873 1 +Hemoglobin biosynthetic process 0.7769483427888861 2.436934803050609 0.0148123497310377 1.0 0.1027348360766125 2 Q99873 1 +Regulation of hemoglobin biosynthetic process 0.7769483427888861 2.436934803050609 0.0148123497310377 1.0 0.1027348360766125 2 Q99873 1 +Intracellular protein transmembrane transport 0.6261170891339104 2.3995746026459757 0.0164141347259825 1.0 0.1089037851071478 21 O60830,Q99595,O43615 3 +Positive regulation of protein exit from endoplasmic reticulum 0.8428558198287293 2.3765893309246495 0.0174735298217165 1.0 0.1147205790910687 3 Q92544 1 +Leukocyte homeostasis 0.7986574429206497 2.3730158715920076 0.0176435057493455 1.0 0.1155112856626189 10 P14174,P09429,O95067 3 +Establishment of protein localization to mitochondrial membrane 0.7156962172276711 2.3690609453215443 0.0178333145646352 1.0 0.1163233623480279 14 Q9Y5J9,Q9Y5L4,Q9P0J0,Q9NS69 4 +Mononuclear cell differentiation 0.4571547122736893 2.367314330354821 0.017917707844681 1.0 0.1163233623480279 51 O96005,P24390,Q00534,P25490,O43290,P09429,P62753,P04062,Q5JVF3,Q6NYC1,O00625 11 +Tetrapyrrole catabolic process 0.918910474810926 2.3645862296573186 0.0180502248050817 1.0 0.1168608800376624 4 P30519,P09601 2 +Endothelial cell activation 0.7587339504329678 2.3495697873061183 0.0187951204378915 1.0 0.1188060833224357 2 O14744 1 +Regulation of cardiocyte differentiation 0.7587339504329627 2.3495697873060917 0.0187951204378928 1.0 0.1188060833224357 2 Q9H2U1 1 +Secondary palate development 0.7587339504329392 2.3495697873059775 0.0187951204378986 1.0 0.1188060833224357 2 Q12959 1 +Protein insertion into mitochondrial inner membrane 0.8990763142437332 2.348594196133625 0.0188444320376524 1.0 0.11882006133113 5 Q9Y5L4,Q9P0J0 2 +Lens fiber cell differentiation 0.8358287131893909 2.345832796629833 0.01898462185999 1.0 0.119014065569928 3 P08670 1 +Positive regulation of mitophagy 0.8334662140224574 2.3354695326820636 0.0195189057197742 1.0 0.120156419646328 3 P21796 1 +Negative regulation of protein targeting to mitochondrion 0.7551507912809834 2.3322854015872783 0.0196856819923838 1.0 0.1209329139258443 2 P49257 1 +Pyridine nucleotide biosynthetic process 0.9106207446873033 2.331276584121847 0.0197387801182802 1.0 0.1209533136637528 4 P43490 1 +Smad protein complex assembly 0.7545535980889776 2.3294015525551135 0.0198378029041066 1.0 0.1214460616812382 2 Q13485 1 +Homeostasis of number of cells 0.4302674901266471 2.3216531608931854 0.0202516189345982 1.0 0.123170610593838 63 Q15648,P04062,Q16512,Q14157,Q9NYV6,Q00534,P26583,O95067,P09601,Q96JB5,P14174,O94874,Q99873,Q96EY1,Q9GZZ9,P18074,P09429,P62753,Q6NYC1 19 +Base excision repair ap site formation 0.7527620185129895 2.3207446652915595 0.0203006285566704 1.0 0.1233537262205135 2 P13051 1 +Error free translesion synthesis 0.8297491039426503 2.3191408046337796 0.0203874028903698 1.0 0.1237657593140036 3 P28340,Q9UBZ9 2 +Apoptotic cell clearance 0.8255829746497305 2.316751111758536 0.0205172935592345 1.0 0.1242076602667578 8 Q6NYC1,P09429,Q8WTV0 3 +Positive regulation of synaptic transmission gabaergic 0.7506718423409716 2.310634847241567 0.0208530327521592 1.0 0.1257734674127459 2 P27695 1 +Protein insertion into membrane 0.5829391385877672 2.3065391972484233 0.0210805225439105 1.0 0.1267940001120372 24 Q9Y5L4,O43681,Q9P0J0,O14737,Q15006,Q9Y5J9,Q9P0I2,Q9NS69,Q96A33 9 +T helper 1 cell differentiation 0.8264940077803163 2.3048181982028324 0.0211767574646337 1.0 0.1271384721381784 3 P09429 1 +T helper 1 type immune response 0.8264940077803163 2.3048181982028324 0.0211767574646337 1.0 0.1271384721381784 3 P09429 1 +Regulation of integrin activation 0.7485816661689942 2.300514146679692 0.0214191087558188 1.0 0.1282395447160311 2 O94887 1 +Meiotic spindle assembly 0.8246082620623899 2.2965108130731737 0.021646691615879 1.0 0.1288926181434551 3 O95067 1 +Regulation of membrane lipid distribution 0.823063502396112 2.289700134766524 0.0220387056023469 1.0 0.1294550789927241 3 P08183 1 +Lipid translocation 0.823063502396112 2.289700134766524 0.0220387056023469 1.0 0.1294550789927241 3 P08183 1 +Tetrapyrrole metabolic process 0.6172898806919881 2.28706515232549 0.0221920205226442 1.0 0.1300277986569643 20 P53004,P09601,P36551,P30519 4 +Positive regulation of pinocytosis 0.8994593893648504 2.2862393396272087 0.0222402604723956 1.0 0.1300537095366077 4 Q9P2R3,P50897 2 +Regulation of pinocytosis 0.8994593893648504 2.2862393396272087 0.0222402604723956 1.0 0.1300537095366077 4 Q9P2R3,P50897 2 +Protein import into peroxisome matrix 0.8202414648565004 2.2772453970360287 0.0227715755921833 1.0 0.1316865514209267 3 O75381 1 +Retrograde transport vesicle recycling within golgi 0.820166930991545 2.2769162284663698 0.0227912285949989 1.0 0.1316865514209267 3 Q8TBA6 1 +Plus end directed organelle transport along microtubule 0.7420125410570277 2.268635538116619 0.0232904986092381 1.0 0.1333278894069194 2 P33176 1 +Protein import 0.4015563505842483 2.263531996252061 0.0236029145289318 1.0 0.1349979142995697 84 O60830,Q99595,O43615,Q13043,P55735,Q9NS69,P61960 7 +Lymphocyte apoptotic process 0.6943255568013171 2.2537187972977617 0.024213864058602 1.0 0.1366771464011572 14 P24390,P14174 2 +Negative regulation of interleukin 2 production 0.8148148148148094 2.2532495371598227 0.024243419578311 1.0 0.1366771464011572 3 P15311,Q92993 2 +Organic acid transmembrane transport 0.5651104423058831 2.2531046855295496 0.0242525491162335 1.0 0.1366771464011572 25 Q9H2D1,P08183,P53007,Q9UBX3 4 +Tangential migration from the subventricular zone to the olfactory bulb 0.7384293819050425 2.2512021244930724 0.0243727384106224 1.0 0.1367639646326173 2 Q02218 1 +Olfactory lobe development 0.7384293819050425 2.2512021244930724 0.0243727384106224 1.0 0.1367639646326173 2 Q02218 1 +Smooth muscle cell chemotaxis 0.7384293819050374 2.2512021244930445 0.0243727384106242 1.0 0.1367639646326173 2 Q9BR76 1 +Regulation of smooth muscle cell chemotaxis 0.7384293819050374 2.2512021244930445 0.0243727384106242 1.0 0.1367639646326173 2 Q9BR76 1 +Peptidyl methionine modification 0.8906470561258865 2.2505281387390257 0.0244154393439686 1.0 0.136885873847714 4 Q9BXJ9,P53582 2 +Leydig cell differentiation 0.7375335921170482 2.2468388126453376 0.02465033029093 1.0 0.1378475196903249 2 Q15637 1 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.8122967723090286 2.2420946248192695 0.0249552573325972 1.0 0.1387493938166813 3 Q99996 1 +Negative regulation of leukocyte degranulation 0.8117399440450774 2.239626128724894 0.0251152049595013 1.0 0.1390176654501322 3 P09601 1 +Negative regulation of myeloid leukocyte mediated immunity 0.8117399440450774 2.239626128724894 0.0251152049595013 1.0 0.1390176654501322 3 P09601 1 +Protein depalmitoylation 0.8717522791750931 2.235815437974719 0.0253638632609995 1.0 0.1394778647049679 5 Q9NUJ1 1 +Macromolecule depalmitoylation 0.8717522791750931 2.235815437974719 0.0253638632609995 1.0 0.1394778647049679 5 Q9NUJ1 1 +Positive regulation of protein localization to early endosome 0.8716950732207207 2.23557790995846 0.0253794329253393 1.0 0.1394778647049679 5 P35241,Q8TDB6,P15311 3 +Regulation of protein localization to endosome 0.8716950732207207 2.23557790995846 0.0253794329253393 1.0 0.1394778647049679 5 P35241,Q8TDB6,P15311 3 +Cell recognition 0.5810932619502772 2.2274386315758647 0.0259179729690426 1.0 0.1411858861402105 23 P45880,P35613,Q6NYC1,Q14157,P26038,Q8WTV0,Q12959 7 +Regulation of g0 to g1 transition 0.8065510576932086 2.2165926692494016 0.0266509389751847 1.0 0.1438986032269118 3 O14757 1 +G0 to g1 transition 0.8065510576932086 2.2165926692494016 0.0266509389751847 1.0 0.1438986032269118 3 O14757 1 +Establishment of protein localization to organelle 0.3289737775669957 2.2164820456503636 0.0266585061755035 1.0 0.1438986032269118 175 O60830,Q99595,O95376,Q15648,O43615,P09132,P49257,Q9Y5J9,P51572,Q7L5D6,P55735,Q9NS69,O75381,P33908,P40855,Q14108,Q9P0J0,Q8N4H5,P50542,Q13043,Q10713,O43681,O14737,P12270,Q8IWJ2,P49458,Q06481,Q9Y5L4,P61960,Q8N1F7 30 +Snrna transcription by rna polymerase iii 0.7294714840250673 2.2074800751720134 0.0272805375047298 1.0 0.1453016636394317 2 P55199 1 +Negative regulation of interleukin 6 production 0.8043963332385907 2.2070117434386844 0.0273132389183643 1.0 0.1453016636394317 3 P04062 1 +Cellular response to cadmium ion 0.8644837766182826 2.205588537421416 0.0274128223879974 1.0 0.145443966588676 5 O15111 1 +Mitochondrial respiratory chain complex assembly 0.4971865360237974 2.203658522960482 0.0275483681846857 1.0 0.145934209221871 35 Q9P0J0,Q00059,P51970,Q9NVA1,O43676,Q9H061,Q9BSK2,O75306 8 +Ether metabolic process 0.8247843757047251 2.2036361089757106 0.0275499457188699 1.0 0.145934209221871 7 P07099 1 +Neuromuscular synaptic transmission 0.8028230608690371 2.2000102744479473 0.0278061660715205 1.0 0.1468054058253201 3 Q8IUD2 1 +Regulation of mitochondrial dna replication 0.7996122653279547 2.185705842686306 0.0288371331656991 1.0 0.1515618232128462 3 Q04837 1 +Immunological synapse formation 0.7994472515583204 2.184970125578629 0.0288910370942048 1.0 0.1515618232128462 3 Q12959 1 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.7246939384891058 2.184081176067828 0.0289562836364676 1.0 0.151782093985211 2 P61254 1 +Membrane lipid biosynthetic process 0.6235525543930308 2.1811125361211077 0.0291750938409363 1.0 0.1524392813498401 18 O15269,Q96G23,Q06136,P04062,Q92643,Q96S52,Q8NBX0 7 +Pyridine containing compound catabolic process 0.8559266435919275 2.169881924823237 0.0300157919632733 1.0 0.1558860316368431 5 Q13126 1 +Diol biosynthetic process 0.8169463256708298 2.1691192619416446 0.0300736306820081 1.0 0.1558860316368431 7 P04062 1 +Diol metabolic process 0.8169463256708298 2.1691192619416446 0.0300736306820081 1.0 0.1558860316368431 7 P04062 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.7945019815307863 2.1628960558622037 0.0305491752065698 1.0 0.1578494991275335 3 P55263 1 +Negative regulation of biomineralization 0.7199163929531207 2.1606266676822905 0.0307241897179815 1.0 0.1586282136863508 2 Q13464 1 +Regulation of water loss via skin 0.8648740044899652 2.1453202116872836 0.0319272535763417 1.0 0.1626414769357257 4 P16949,P04062 2 +Regulation of golgi organization 0.7509099004212921 2.1442686525979364 0.0320113670213924 1.0 0.1628263298375735 10 Q9Y4I1,Q99996,P36507,P50570,P27361,Q9P2W9 6 +Negative regulation of amyloid beta clearance 0.7899495659129439 2.142532109586074 0.0321506876758901 1.0 0.1632804574107852 3 Q16850 1 +Membrane to membrane docking 0.789127837514928 2.1388519195511404 0.0324476630405889 1.0 0.1640228418351171 3 P15311,P26038 2 +Regulation of macroautophagy 0.4194207500467214 2.1385168850039245 0.0324748152068095 1.0 0.1640228418351171 59 Q86YR5,O15269,Q9UNH7,Q9H2M9,Q9Y5K8,P42345,P48426,Q93050,P09601,P54646,P12235,P27361,P04062,P21796,Q9UPT5,P17252,Q9Y487,Q9Y2S7 18 +Inner mitochondrial membrane organization 0.629595397428759 2.12985171998179 0.0331838571596279 1.0 0.1657879972110874 17 Q9Y5L4,Q9P0J0,Q9Y5J9,O60313,Q9NVH1,Q13505 6 +Positive regulation of erad pathway 0.784374846223064 2.1175387816151563 0.0342141475247821 1.0 0.1691210860239121 3 P51572 1 +Peroxisome fission 0.7843235470230773 2.11730850316485 0.0342336737109389 1.0 0.1691210860239121 3 O00429 1 +Positive regulation of mitochondrial translation 0.8256480435157945 2.1050086894360813 0.0352905516772108 1.0 0.1726432835423373 6 Q567V2 1 +Regulation of hair follicle development 0.7085697223051641 2.104701326280542 0.0353173149712779 1.0 0.1726447921367492 2 Q13485 1 +N terminal protein amino acid acetylation 0.8017008936246979 2.1016353963870813 0.0355852267127634 1.0 0.1736942330048572 7 Q86UY6,Q9BXJ9,P41227 3 +Leukocyte differentiation 0.402136238006423 2.0999084521354168 0.0357368951083656 1.0 0.1743041685180823 71 O96005,P24390,O94887,Q00534,P25490,P17252,O43290,P09429,Q6IAN0,P62753,P04062,Q5JVF3,Q6NYC1,O00625 14 +B cell homeostasis 0.7803684885416843 2.099538839071934 0.0357694278057474 1.0 0.1743325510532544 3 P14174 1 +Sphingoid metabolic process 0.8388255667496096 2.0981363709179313 0.0358931004625961 1.0 0.1745898516194192 5 P04062,Q06136 2 +Excretion 0.8008893060073223 2.098030179893885 0.0359024794473277 1.0 0.1745898516194192 7 P09601 1 +Positive regulation of vascular endothelial cell proliferation 0.7796352126137938 2.096240911020606 0.0360608254798149 1.0 0.1747176684018533 3 P09429 1 +Vascular endothelial cell proliferation 0.7796352126137938 2.096240911020606 0.0360608254798149 1.0 0.1747176684018533 3 P09429 1 +Regulation of protein exit from endoplasmic reticulum 0.8528781371602577 2.095968437703966 0.0360849908818836 1.0 0.1747176684018533 4 Q92544,Q8IWJ2 2 +Modification of synaptic structure 0.773625975236883 2.0804658616786975 0.0374828237312185 1.0 0.1780271741939913 8 Q9UQB8 1 +Regulation of ribosome biogenesis 0.7741935483870908 2.071733859096222 0.0382902678597358 1.0 0.1797714302536952 3 Q96BK5,Q96DE0 2 +Neuron apoptotic process 0.4233969862711677 2.0648511987012497 0.0389370817908842 1.0 0.1822836411530207 53 Q9NR28,P78362,Q9UNH7,Q15233,P09601,P50897,P04062,Q96A26 8 +T cell apoptotic process 0.7317005504838361 2.050716100566229 0.0402946021001444 1.0 0.1859707024791674 10 P24390 1 +Protein o linked glycosylation via threonine 0.696625858465199 2.0455015097160003 0.0408054405198845 1.0 0.187797112011824 2 Q10472 1 +Nucleotide excision repair dna gap filling 0.6963272618692167 2.0440172250047683 0.04095184552127 1.0 0.1879365110179904 2 P28340 1 +T cell differentiation 0.4987088465055781 2.0419155160590283 0.0411599123900108 1.0 0.1886303288323108 30 O96005,P24390,Q00534,O43290,P09429,P62753,P04062 7 +Regulation of anaphase promoting complex dependent catabolic process 0.6957300686771971 2.041048033286696 0.0412460529586686 1.0 0.1886724195574815 2 P24941 1 +T cell activation 0.4082491013676891 2.039737204952994 0.0413765071819687 1.0 0.1886724195574815 61 O96005,P24390,Q00534,Q9BY67,O43290,P09429,P51159,P62753,P04062,Q6NYC1,P26038,Q12959 12 +Polyamine biosynthetic process 0.6954314720812222 2.039563126546543 0.0413938577988612 1.0 0.1886724195574815 2 P19623 1 +Protein localization to endoplasmic reticulum 0.4908223305431403 2.038918065520257 0.0414582055846504 1.0 0.1886724195574815 32 P24390,O43681,Q9H2M9,P09132,O76094,Q9UHB9,P51572,P49458,Q7L5D6,P33908,Q9Y5M8,Q96HY6 12 +Positive regulation of translation 0.4157315954192467 2.034317168958338 0.0419196272187449 1.0 0.1904038844268919 55 O95900,Q7Z739,P67809,Q14103,P42345,P08670,P61254,Q567V2,Q00839,Q13144,P51116,Q92552,Q9H074 13 +Sphingosine biosynthetic process 0.8372624834048155 2.0313672064257027 0.0422177584764373 1.0 0.1914614953559627 4 P04062 1 +Localization within membrane 0.3167495860535785 2.0275407236377823 0.0426071441028155 1.0 0.1925213071324678 177 Q15006,P09132,Q9Y5J9,P50570,Q14651,Q9NS69,P40855,P35613,Q12959,P49354,Q9P0J0,P50542,Q14254,P07602,P15311,Q9HD20,Q9HD45,Q12846,Q4J6C6,O43681,O14737,Q8IWJ2,P49458,Q9UPT5,O60725,P35241,Q9Y4I1,Q9Y5L4,O75122,Q9P0I2,O00264,Q86TV6,Q9UJ41,Q92544,Q15036,P63000,Q9BTX1 37 +Activation induced cell death of t cells 0.7642299418253439 2.026712325505055 0.042691841226176 1.0 0.1925213071324678 3 P62753 1 +Positive regulation of endothelial cell apoptotic process 0.7631421744324931 2.021785551069214 0.043198511111802 1.0 0.1940216679391743 3 Q4KMQ2,P19174 2 +Glycosyl compound biosynthetic process 0.7600665189728046 2.017870788129195 0.0436047200898528 1.0 0.1946404947376057 8 P55263,Q9NRG1,Q13126 3 +Folic acid metabolic process 0.7599960242423671 2.0175443829922184 0.0436387342213939 1.0 0.1946591794455345 8 Q9H2D1 1 +Stem cell proliferation 0.6880269912461885 2.0165170364286102 0.0437459385842116 1.0 0.1949806506197439 12 P35240,P26583,Q00839,P04062,P08183 5 +Mitochondrial rna metabolic process 0.5095066635123892 2.0159524772577178 0.0438049453781521 1.0 0.1949806506197439 28 Q12849,P41250,O15091,O00411,Q00059,Q9Y606,Q7L8L6,Q8IYB8,Q9BSK2,Q9BW92,Q969Z0 11 +Lymphocyte homeostasis 0.7823211469038455 2.015201250937062 0.0438835665195074 1.0 0.1949806506197439 7 P14174,O95067,Q16512,P62753 4 +Positive regulation of potassium ion transmembrane transporter activity 0.8330720994885317 2.0139640822128513 0.0440133046376933 1.0 0.1953951197725081 4 Q99996 1 +Phagocytosis recognition 0.7611785082323628 2.01288588079677 0.0441266362670338 1.0 0.1957650770079285 3 Q8WTV0 1 +Membrane organization 0.3108568673496316 2.0057373549532387 0.0448842774986126 1.0 0.1973954216111161 216 Q15006,Q86XL3,Q9Y5J9,Q15075,Q8WUX9,Q9UNZ2,P50570,Q7L5D6,P55735,Q9NS69,Q9UQB8,O75431,O75844,P08183,O95235,Q15392,Q14185,P49354,P45880,Q12959,Q9P0J0,P46379,P51790,P50542,Q9H267,Q14254,Q9NVH1,O60313,Q4KMQ2,Q12846,Q99747,Q9Y5P4,Q00169,P42356,O43681,Q01082,O14737,P48426,Q9UKS6,O00429,Q06481,Q96EY1,Q9P2W9,P17252,Q9Y2J2,Q9Y5L4,O43760,P20700,Q9P0I2,O15400,Q9NX63,P50897,P12235,Q5JTV8,P02545,Q9P2R3,Q9UNF0,Q8NB49,Q96A33,Q13505,P16615,P63000,Q01968,Q8N1F7 64 +Negative regulation of guanyl nucleotide exchange factor activity 0.8284787346497007 1.994854890942405 0.0460587085916284 1.0 0.200765060050696 4 P16949,Q86YR5 2 +Golgi organization 0.411973148828443 1.9931958634433544 0.0462400039022179 1.0 0.2013090496770342 55 P49257,P83436,Q9UNZ2,Q14789,P50570,Q99996,Q7Z392,Q5VU43,O14744,Q8TAT6,P36507,O60763,Q8IWJ2,Q9Y2L5,Q9P2W9,Q9Y4I1,Q08379,O75122,Q8TBA6,P27361,Q9Y3B3,P49755 22 +Regulation of nervous system process 0.6651095681592802 1.991763052030274 0.0463970619586124 1.0 0.2018581508946033 13 P04062,Q9UQB8 2 +Nucleoside salvage 0.7989139633153773 1.9894469937134545 0.046651886987725 1.0 0.2021581769468085 6 P55263,Q13126 2 +Purine nucleoside biosynthetic process 0.7989139633153773 1.9894469937134545 0.046651886987725 1.0 0.2021581769468085 6 P55263,Q13126 2 +Purine ribonucleoside salvage 0.7989139633153773 1.9894469937134545 0.046651886987725 1.0 0.2021581769468085 6 P55263,Q13126 2 +Positive regulation of smad protein signal transduction 0.7547789725209038 1.9838312765540915 0.0472746521952791 1.0 0.2041347351912709 3 Q13485,Q8N1F7 2 +T cell homeostasis 0.8257628454602668 1.9835404802728431 0.0473070900722776 1.0 0.2041347351912709 4 O95067 1 +Steroid catabolic process 0.8247414399902404 1.9792822699611916 0.047784234665603 1.0 0.2050229555737838 4 Q8WTV0 1 +Regulation of mitochondrial gene expression 0.7343856686061618 1.978005650111526 0.0479280692624759 1.0 0.2052352887184501 9 O95900,Q567V2,Q92552 3 +Macropinocytosis 0.7528999151637457 1.9752854908437747 0.0482357588370239 1.0 0.2059259016923875 3 Q06481 1 +Mitochondrial genome maintenance 0.7335278044123411 1.9739025733752464 0.0483928221099996 1.0 0.2062779602154523 9 P51530,Q9BSK2,P12235 3 +Negative regulation of neuron apoptotic process 0.5164066809058391 1.9718398307742393 0.0486278937940507 1.0 0.2066052310546713 26 Q9UNH7,Q15233,P09601,P50897,P04062 5 +Calcium mediated signaling using intracellular calcium source 0.7513683709342296 1.9683152808080824 0.0490317728184961 1.0 0.2072839088709365 3 P17252 1 +Negative regulation of vascular associated smooth muscle cell differentiation 0.6808002388772769 1.9665518405257607 0.049234900244711 1.0 0.2078311507095627 2 Q53EL6 1 +Positive regulation of endothelial cell chemotaxis 0.6793072558972713 1.9590744436190668 0.0501040692430692 1.0 0.2096020230001728 2 Q9NWH9 1 +Regulation of endothelial cell chemotaxis 0.6793072558972713 1.9590744436190668 0.0501040692430692 1.0 0.2096020230001728 2 Q9NWH9 1 +T cell differentiation involved in immune response 0.8185385638664837 1.9533873557136625 0.0507737133549057 1.0 0.2117170467122457 4 P09429 1 +Constitutive secretory pathway 0.7473118279569819 1.949832492268528 0.0511960874522903 1.0 0.2123513649948392 3 Q7Z392,P51159 2 +Outer mitochondrial membrane organization 0.8028219315162709 1.945444633234663 0.0517214873056455 1.0 0.2134230717518496 5 Q9NS69 1 +Ceramide transport 0.7885938960081493 1.944501082845993 0.0518350549688448 1.0 0.2134230717518496 6 P08183 1 +Regulation of dendrite extension 0.8162484781599959 1.9438118106367537 0.0519181489964573 1.0 0.2135846019318552 4 Q96PU5 1 +Nucleobase containing small molecule biosynthetic process 0.7663932971965335 1.9436328370159075 0.0519397430686261 1.0 0.2135846019318552 7 P55263,Q13126 2 +Purine containing compound salvage 0.7429384335881014 1.9382729073316445 0.0525899359563888 1.0 0.2149469776420752 8 P55263,Q13126 2 +Regulation of response to interferon gamma 0.7446276825450313 1.937586060044651 0.0526737445320812 1.0 0.2151119254169978 3 Q15648 1 +Engulfment of apoptotic cell 0.6742311137652847 1.933614267563684 0.0531605717317213 1.0 0.2166932486703396 2 P63000 1 +Calcium ion regulated exocytosis of neurotransmitter 0.7432169437819879 1.9311442668326593 0.0534652140165921 1.0 0.2177244342726088 3 P16615 1 +Mitochondrial translation 0.4349495877448749 1.9266669666614973 0.0540211471281415 1.0 0.2192709209439 44 P46199,O95900,Q16540,Q567V2,Q96EY7,Q9BW92,Q9Y3D3 7 +Isopentenyl diphosphate biosynthetic process 0.7421988411881719 1.9264930981496855 0.0540428328198423 1.0 0.2192709209439 3 Q15126 1 +Response to arsenite ion 0.6718423409973145 1.9216133918155929 0.0546544222569229 1.0 0.2205453423982844 2 Q9H2U1 1 +Aggresome assembly 0.6718423409973143 1.9216133918155909 0.0546544222569231 1.0 0.2205453423982844 2 Q9UBN7 1 +Protein localization to cytoplasmic stress granule 0.7612568325531022 1.9204541181624837 0.0548005633258834 1.0 0.2208946734186012 7 P31483,P67809,P05455 3 +Regulation of guanyl nucleotide exchange factor activity 0.7962366526143259 1.917283858756232 0.0552018794147111 1.0 0.2219639341099228 5 P16949,Q86YR5,Q9NWH9 3 +Organelle disassembly 0.409616206643846 1.9167683906968744 0.0552673623406883 1.0 0.2220903981744654 53 P49815,P52789,P04062,P21796,Q99623,Q96HY6,P46199,Q99986,Q9ULC4,Q9Y3C8,Q16543,O95140,Q7KZI7,O94874,O00429,Q9GZZ9,Q08379,P12235,Q9UBN7,P61960 20 +Positive regulation of cytoplasmic transport 0.7954493785318185 1.9139125654014864 0.0556313285862122 1.0 0.2230037164334281 5 P35241,P15311 2 +Positive regulation of early endosome to late endosome transport 0.7954493785318185 1.9139125654014864 0.0556313285862122 1.0 0.2230037164334281 5 P35241,P15311 2 +Spermatid nucleus differentiation 0.8085031013125751 1.91136605246972 0.0559575560980765 1.0 0.2238988418737261 4 P26583,Q14997 2 +Negative regulation of sister chromatid cohesion 0.7381458921544273 1.9079587311011417 0.0563965504036416 1.0 0.2252410574872494 3 P41227 1 +Folic acid containing compound metabolic process 0.6184457704761682 1.9052540798026527 0.0567470514636943 1.0 0.2263638495428294 15 Q9H2D1,P00374 2 +Protein localization to early endosome 0.7572409035152596 1.9022989430086183 0.0571320837998414 1.0 0.2274825984611137 7 P35241,Q8TDB6,P15311 3 +Negative regulation of establishment of protein localization to mitochondrion 0.7365588910085465 1.9006932390787925 0.0573422046329934 1.0 0.2276804550733718 3 P49257 1 +Positive regulation of dopamine receptor signaling pathway 0.6676619886533216 1.9005820374392348 0.0573567801333094 1.0 0.2276804550733718 2 O14744 1 +Regulation of dopamine receptor signaling pathway 0.6676619886533216 1.9005820374392348 0.0573567801333094 1.0 0.2276804550733718 2 O14744 1 +Trna wobble base modification 0.791821603418156 1.8983648574543948 0.0576480356316289 1.0 0.2282834226529188 5 Q2VPK5 1 +Trna wobble uridine modification 0.791821603418156 1.8983648574543948 0.0576480356316289 1.0 0.2282834226529188 5 Q2VPK5 1 +Positive regulation of chemokine production 0.777087222870637 1.8941741681694328 0.0582018956723602 1.0 0.229501855684485 6 P14174,P09601 2 +Respiratory chain complex iii assembly 0.7892787040590644 1.8874542695897312 0.0590992516425483 1.0 0.2321920921215648 5 Q9NVA1,Q9BSK2 2 +Dendrite extension 0.7741175656971072 1.8811500490193147 0.0599515103919032 1.0 0.23332012355569 6 Q96PU5,Q9Y263,Q96F07 3 +Vitamin transmembrane transport 0.752192389340558 1.8794351735612431 0.0601850973790663 1.0 0.2339296876091642 7 Q9H2D1,P04062,Q8WTV0 3 +Pteridine containing compound metabolic process 0.5733972272583173 1.8720276171116288 0.0612027828395405 1.0 0.2369232839444714 18 Q9H2D1,P00374 2 +Signal transduction involved in regulation of gene expression 0.6619886533293524 1.8719796625292973 0.0612094172127457 1.0 0.2369232839444714 2 P09874 1 +Dicarboxylic acid catabolic process 0.7283133719840377 1.8698556567506197 0.0615038650239316 1.0 0.237640155799987 8 Q4G176 1 +Thalamus development 0.6604956703493583 1.8644414380021856 0.0622597382779082 1.0 0.2394266658819263 2 Q02218 1 +Crd mediated mrna stabilization 0.7103751949103594 1.8625954810922143 0.0625192006125829 1.0 0.2401414380210221 9 Q00839,Q14103,P67809,Q9H074 4 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.7103751949103594 1.8625954810922143 0.0625192006125829 1.0 0.2401414380210221 9 Q00839,Q14103,P67809,Q9H074 4 +Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization 0.7281959378733517 1.8623329262467403 0.0625561770984983 1.0 0.2401421245557649 3 Q9UBN7,O95140 2 +Enzyme directed rrna pseudouridine synthesis 0.6593012839653665 1.8584075115813072 0.0631111663925483 1.0 0.2417039154212267 2 Q9UJK0 1 +Regulation of dna ligation 0.7271385311401612 1.8574739671206233 0.0632437515889772 1.0 0.2420696321816219 3 P09429 1 +Sterol metabolic process 0.4464071780025899 1.8565555270491865 0.0633744161588854 1.0 0.2424275731845756 38 P37268,Q13907,Q15125,Q15126,P04062,Q16850,Q15036,Q14534,Q8WTV0,Q15800,Q15392 11 +Dna geometric change 0.3969952013990926 1.8542407964601917 0.0637047179010332 1.0 0.2428482917128281 56 Q04837,Q8IYB8,Q9BRT9,P25205,P26583,Q86WJ1,P51530,P17096,P46063,Q12873,P19447,P33991,Q14566,P18074,Q9H2U1,P33992,P09429,P54132,Q9Y4B4,Q8WVB6 20 +Glycine biosynthetic process 0.7264306658829001 1.854220130619325 0.0637076732167272 1.0 0.2428482917128281 3 P00374 1 +Negative regulation of muscle tissue development 0.6581068975813678 1.8523706266093032 0.0639726202399426 1.0 0.2431481186289258 2 Q8IXJ6 1 +Negative regulation of muscle organ development 0.6581068975813678 1.8523706266093032 0.0639726202399426 1.0 0.2431481186289258 2 Q8IXJ6 1 +Positive regulation of fibroblast proliferation 0.7228845166720028 1.84435684896065 0.0651311515909924 1.0 0.24623842328089 8 P14174 1 +Inorganic anion transport 0.5161655043980807 1.837569278107888 0.0661258992896978 1.0 0.2471578572534753 24 P08183,P45880,P21796,Q9UHG3 4 +Ribonucleoside metabolic process 0.7209107343800856 1.835072807060496 0.0664949024506298 1.0 0.2472625261497494 8 P55263,Q13126,O60725 3 +Purine ribonucleoside metabolic process 0.7209107343800856 1.835072807060496 0.0664949024506298 1.0 0.2472625261497494 8 P55263,Q13126,O60725 3 +Cytoplasmic microtubule organization 0.5470352957469417 1.8343636471943243 0.066600032084062 1.0 0.2475124199206088 20 P15311,Q03001,P23258,Q9BSJ2,Q9UIS9,Q12959 6 +Positive regulation of protein localization to cell surface 0.7768287394319624 1.8338919186029323 0.06667003942515 1.0 0.2475850953265116 5 Q92544 1 +Export across plasma membrane 0.703473599889636 1.8292092872300871 0.0673682616900008 1.0 0.248668142414562 9 P08183 1 +Cellular copper ion homeostasis 0.7198327359617623 1.8238503559036745 0.0681746986286166 1.0 0.2506765416123246 3 O60826,O43819 2 +Outer ear morphogenesis 0.7194728266342467 1.82219160536092 0.0684259178823438 1.0 0.2511515973566794 3 P27361 1 +Caveolin mediated endocytosis 0.7869577833066435 1.820639085002086 0.0686617374284921 1.0 0.251573604904335 4 Q96PU5,Q9UNF0 2 +Protein ufmylation 0.7599402092675683 1.818776097721242 0.0689455964369818 1.0 0.2522079385357306 6 O94874,P61960,Q96JB5,Q9GZZ9,Q96HY6 5 +Protein lipid complex subunit organization 0.7721085107417566 1.81352320110906 0.0697511634990724 1.0 0.2542008815176723 5 Q8WTV0 1 +Glycoside metabolic process 0.700236890091628 1.8135203940363396 0.0697515960393611 1.0 0.2542008815176723 9 Q9NUJ1 1 +Endomembrane system organization 0.318349026826157 1.8134083640254424 0.0697688604796482 1.0 0.2542008815176723 166 Q15006,Q9H2M9,P49257,Q86XL3,P83436,Q8WUX9,Q15075,Q9UNZ2,Q14789,P50570,Q7L5D6,Q8IYI6,Q9UQB8,Q14108,Q99996,O75844,Q7Z392,P46379,P51790,Q9H267,P50542,Q5VU43,O14744,Q99816,Q4KMQ2,Q12846,Q8TAT6,Q9Y5P4,O43681,Q01082,A0MZ66,P36507,O60763,Q9UKS6,Q8IWJ2,O00429,Q9Y2L5,Q9P2W9,P17252,Q9Y4I1,Q9Y2J2,O43760,Q08379,O75122,Q8TBA6,P20700,Q9P0I2,P51159,P27361,P02545,Q9Y3B3,Q9UNF0,Q5JTV8,Q96A33,P16615,Q8N1F7 56 +Positive regulation of anion transport 0.7586029106860286 1.8128762310396296 0.0698509130062277 1.0 0.2542008815176723 6 P08183 1 +Pyridine nucleotide metabolic process 0.7575450042988167 1.808207025151554 0.0705742856582483 1.0 0.25555863645523 6 P43490 1 +Glycoside catabolic process 0.7575401016309167 1.8081853825871588 0.0705776528660016 1.0 0.25555863645523 6 Q9NUJ1 1 +Long chain fatty acyl coa biosynthetic process 0.7574994012835907 1.808005711661707 0.0706056116348115 1.0 0.25555863645523 6 Q4G176 1 +Response to mitochondrial depolarisation 0.7150451719342501 1.8074416724206663 0.0706934413626703 1.0 0.2555930184669177 8 P52789,Q9UBN7,P04062,Q16543,O95140 5 +Protein localization to synapse 0.6634178225044206 1.7958955326180133 0.0725111330844825 1.0 0.2607440349053226 11 Q9UQB8 1 +Establishment of pigment granule localization 0.7807407890368345 1.794335166624891 0.0727596882953269 1.0 0.2611824674451616 4 P51159,Q13561 2 +Protein auto adp ribosylation 0.6461630337414165 1.7918425817834915 0.0731581856680687 1.0 0.2624685649641653 2 P09874 1 +Regulation of catabolic process 0.2767468058594859 1.7884622975731257 0.0737014531990554 1.0 0.2639822632146189 327 Q7Z739,P67809,Q09472,Q86YR5,O15269,O95376,Q9H2M9,Q93050,Q9NZM5,P51572,Q6ZXV5,P04062,P21796,P54619,Q8IYI6,Q8IYB8,Q14108,O75844,Q9Y487,Q8WTV0,Q8NEZ5,Q92993,Q96HY6,Q15024,Q9P0J0,P07602,P15311,Q9Y5K8,Q14103,O43242,P09601,Q9H2J4,P54646,P62081,Q00839,Q16850,P42345,Q96HR8,Q96JB5,P27695,Q9NWH9,Q9Y2S7,O60506,P24941,Q8TDB6,Q96PU5,O94874,P08670,Q9UKS6,P48426,Q13310,O00429,Q5JVF3,P51116,Q9HCE1,Q9UPT5,P61289,P17252,Q9NNW5,Q969Z0,P35241,Q08379,Q969T7,Q9UNH7,Q9NPI6,Q8NCG7,P09429,Q14147,P12235,P14373,P27361,P62136,P54725,Q9H074,P26038 75 +Negative regulation by host of viral genome replication 0.6452672439534185 1.7872915773567155 0.0738903746280503 1.0 0.2643687416790881 2 O75909 1 +Alcohol biosynthetic process 0.4415775090716864 1.7800536093210109 0.075067187652605 1.0 0.2673223762398828 37 P37268,Q15125,Q15126,P04062,Q16850,P00374,Q15800,Q15392 8 +Lipoprotein metabolic process 0.5587281305943095 1.7799815537014465 0.0750789795857667 1.0 0.2673223762398828 18 P04062,Q9NUJ1 2 +Pigment granule localization 0.7509601119996541 1.7791053907242025 0.0752224850844229 1.0 0.2673223762398828 6 Q9Y4I1,Q9H267,Q13561,P51159 4 +T cell activation involved in immune response 0.7083955228073981 1.7760434574958326 0.0757257546005081 1.0 0.2687072253898661 8 P09429,P51159,P62753 3 +Transcription coupled nucleotide excision repair 0.7757411086807813 1.7731429844837736 0.0762050168594354 1.0 0.2696930260437505 4 P18074,Q9HCS7 2 +Pyridine containing compound metabolic process 0.6755200735164458 1.772399783791414 0.0763282176694106 1.0 0.2699826279190103 10 P43490,Q13126 2 +Proton transporting two sector atpase complex assembly 0.7080754313700477 1.769553151329592 0.0768016090675993 1.0 0.2705598945560761 3 Q92544 1 +Negative regulation of protein containing complex assembly 0.4327718401084052 1.765806103853338 0.0774283841315668 1.0 0.2716653950766694 39 P35241,Q09472,P45880,P52907,P16949,P50542,Q01082,P47755,Q9NZM5,P09429,Q9UBN7,P04062,Q13813,P04350,Q9UBB9 15 +Positive regulation of wound healing spreading of epidermal cells 0.7069892473118214 1.764525736559598 0.077643506214148 1.0 0.2718460262539968 3 Q96AC1,P42345 2 +Blood vessel endothelial cell migration 0.4975340630554342 1.7642667587063203 0.0776870777523384 1.0 0.2718460262539968 25 P19174,P06576,P09429,P09601,P42785,P25705,P35579,P17252,P51608,Q8WTV0,Q4VCS5 11 +Protein polyufmylation 0.7597130902570398 1.759880105217098 0.0784281372067419 1.0 0.2734092005401697 5 O94874,Q9GZZ9,Q96HY6,P61960 4 +Adiponectin activated signaling pathway 0.705485252095799 1.7575614182062584 0.0788221628999061 1.0 0.2743431653785534 3 Q06481 1 +Regulation of anion transport 0.6721797814051849 1.7556470509118831 0.0791486930212874 1.0 0.2750326008406366 10 P08183 1 +Response to muscle activity 0.7715641451291241 1.7554122237340823 0.0791888227060306 1.0 0.2750326008406366 4 Q9UDX5,P54646 2 +Positive regulation of cytoplasmic translation 0.6554774732241626 1.7548639175853824 0.0792825873304359 1.0 0.275211789850226 11 P67809,O60506,Q14103,Q00839,Q9H074 5 +Negative regulation of regulated secretory pathway 0.7572443122357387 1.749170144596649 0.0802616131375031 1.0 0.277429707275077 5 P09601 1 +Chemokine production 0.702201125189686 1.746726576790572 0.0806847780168438 1.0 0.2783705517381815 8 P14174,P09601 2 +Negative regulation of cytokine production 0.451864336139221 1.7439708646151697 0.0811641703874621 1.0 0.2789243685879821 33 P25490,P15311,P09429,P09601,Q9UJ41,P04062,Q06481,P31483,P63000,Q92993 10 +Positive regulation of triglyceride metabolic process 0.7024242163624274 1.743376291308939 0.0812679068760411 1.0 0.2789870385444736 3 Q8WTV0 1 +Embryonic camera type eye morphogenesis 0.636309346073453 1.7416974912771903 0.0815613917285571 1.0 0.2795533836242457 2 Q8IZ21 1 +Embryonic eye morphogenesis 0.636309346073453 1.7416974912771903 0.0815613917285571 1.0 0.2795533836242457 2 Q8IZ21 1 +Positive regulation of catabolic process 0.3212486484709455 1.7408161851346784 0.0817158039956824 1.0 0.2798688120578544 159 Q7Z739,P67809,O15269,Q86YR5,O95376,Q9H2M9,Q9NZM5,P51572,Q6ZXV5,P04062,P21796,Q8IYB8,Q8NEZ5,Q92993,Q96HY6,Q15024,Q9P0J0,P15311,Q14103,P09601,P54646,Q00839,Q96JB5,O60506,Q8TDB6,O94874,P48426,Q96PU5,Q9UKS6,Q9HCE1,P35241,Q969T7,Q9NPI6,Q8NCG7,P26038,P09429,P14373,P12235,P27361,Q9H074,P54725 41 +Response to arsenic containing substance 0.635880324277622 1.74068282602262 0.081739190282297 1.0 0.2798688120578544 12 P09601 1 +Pigment metabolic process 0.4795788501812104 1.7369635977192563 0.0823935964517996 1.0 0.2811159489190977 27 P53004,P09601,P36551,P30519 4 +Protein hydroxylation 0.5769270124932006 1.73574339710315 0.0826092164524245 1.0 0.2813714752445317 16 Q9H267,O60568,O75718,Q32P28,Q6NYC1 5 +Meiotic spindle organization 0.7202466688499835 1.7337615365084098 0.0829604029071344 1.0 0.2824202344141677 7 Q14674,P23258,Q08379,O95067 4 +Positive regulation of gastrulation 0.6342191699014623 1.7310374221166172 0.0834450902109495 1.0 0.2838431947900434 2 O95747 1 +Response to lead ion 0.6997395877565421 1.730923648129522 0.0834653832059597 1.0 0.2838431947900434 3 P36551 1 +Ceramide biosynthetic process 0.6982923060882377 1.7281939466285934 0.083953458649197 1.0 0.2849091373607175 8 P04062 1 +Dna unwinding involved in dna replication 0.563094386552508 1.727537139993328 0.084071241028159 1.0 0.2851605607847014 17 P46063,P33992,P54132,Q04837,Q14566,Q9BRT9,P17096,P25205 8 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.7183578116651168 1.725097189312382 0.0845099589973481 1.0 0.2862023831949631 7 P52789,Q9UBN7,P04062,Q16543,O95140 5 +Organophosphate ester transport 0.4778393917059105 1.723514044168733 0.084795607678489 1.0 0.2868720247329287 27 Q9H2D1,Q00169,P12235,Q9BSK2,Q14108,P08183,Q8WTV0 7 +Selective autophagy 0.4559166395592778 1.7199305318035454 0.0854450698461055 1.0 0.2878048202753672 31 O15269,P49815,Q9Y3C8,O94874,P12235,Q9UBN7,P27361,P21796,Q16543,P61960,Q99623,Q9GZZ9,Q96HY6 13 +Bergmann glial cell differentiation 0.7504932140969789 1.719840329965708 0.085461469422458 1.0 0.2878048202753672 5 P08670 1 +Asymmetric neuroblast division 0.6960826693011677 1.7139436042771286 0.0865390837961657 1.0 0.2897660650865969 3 Q92974 1 +Neuroblast division 0.6960826693011677 1.7139436042771286 0.0865390837961657 1.0 0.2897660650865969 3 Q92974 1 +Mitotic nuclear membrane disassembly 0.6959378733572205 1.7132708700415884 0.0866627188557895 1.0 0.2898405960050215 3 P17252,Q99986 2 +Pyridine containing compound biosynthetic process 0.7359690427163377 1.7126149091085867 0.0867834086107588 1.0 0.2898405960050215 6 P43490 1 +Positive regulation of release of cytochrome c from mitochondria 0.7483102752695718 1.710343632697712 0.087202347752378 1.0 0.290052253533139 5 O00429,Q96A26 2 +Demethylation 0.547323505018919 1.7079515801056733 0.0876453272271478 1.0 0.2910806134780491 18 Q01804,P16435,Q8IUF8,Q16850,Q6NYC1,P27695,Q9Y4C1 7 +Establishment of protein localization to membrane 0.3594340784173443 1.7062728866925851 0.0879572837483295 1.0 0.2918196409464152 85 Q15006,Q9H2M9,P09132,Q9Y5J9,Q9UHB9,Q7L5D6,Q9NS69,P40855,Q9P0J0,P50542,Q9HD20,Q4J6C6,O43681,O14737,Q8IWJ2,P49458,O60725,Q9Y5L4,Q9P0I2,O76094,Q9UJ41,P43307,Q96A33 23 +Hormone catabolic process 0.6941457586618808 1.7049420108722315 0.0882052401471782 1.0 0.2919928572859855 3 P42892,P14735 2 +Mitochondrial dna replication 0.6931339446712945 1.7036990042472535 0.088437334270893 1.0 0.292371855852 8 P51530,Q04837,Q9UJZ1,Q96EY1 4 +Pyramidal neuron differentiation 0.7574644485348115 1.6953935494177623 0.0900007887908371 1.0 0.2952675804137972 4 P04062 1 +Sphingolipid biosynthetic process 0.5937554470773698 1.692810396630444 0.0904915630978258 1.0 0.2957302052965653 14 P04062,O15269,Q96G23,Q06136 4 +Cilium organization 0.380830949023538 1.6905550200423225 0.0909218215537841 1.0 0.2968263168884418 58 Q16181,O75695,Q01968,P61160,Q9Y5K8,Q96FJ2,Q14141,P50570,Q4KMP7,P57076,Q9UIS9,P27695,Q15019,Q66K14 14 +Cytochrome complex assembly 0.6902406969781336 1.6899417104138872 0.091039106782494 1.0 0.2970606054312781 8 Q6DKK2,Q9NVA1,Q9BSK2 3 +Mitochondrial transcription 0.730753271058763 1.6894071427241624 0.0911414331308206 1.0 0.2972458733691833 6 Q00059 1 +Negative regulation of cell aging 0.755681799098417 1.6877876187936118 0.0914520051460345 1.0 0.2976637334578662 4 P67809,P14174 2 +Spleen development 0.6901994205264566 1.68658502903846 0.0916831726452245 1.0 0.298267390170855 3 Q5JVF3 1 +Regulation of smad protein signal transduction 0.7550044816253354 1.6848967418012477 0.0920084953165363 1.0 0.2990194757105232 4 Q13485,Q01082,Q8N1F7 3 +Vitamin transport 0.6889015997763813 1.6835699502504786 0.0922648102094583 1.0 0.2992644887807777 8 Q9H2D1,P04062,Q8WTV0 3 +Glycoprotein catabolic process 0.6891459673798983 1.6816809901990506 0.0926307161847781 1.0 0.3001240924422556 3 P33908 1 +Regulation of microvillus organization 0.7540960916252331 1.681018756054332 0.0927592714857015 1.0 0.3001240924422556 4 P15311 1 +Purine deoxyribonucleotide metabolic process 0.7532420627172318 1.6773719463023695 0.0934697716407937 1.0 0.3011519701118172 4 P55263 1 +Regulation of triglyceride metabolic process 0.752982276633078 1.6762624560026531 0.0936867953869056 1.0 0.301330717937381 4 Q8NCG7,Q8WTV0 2 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.7403858462421347 1.6758173154758311 0.0937739813928653 1.0 0.3014625628422852 5 Q10713,Q9NZM5,O95630 3 +Circadian rhythm 0.3909803565514176 1.6718050419327115 0.0945627722819304 1.0 0.302508162701901 51 Q09472,P43490,P04818,Q15233,Q14103,P42345,P54646,Q00839,Q8WXF1,Q9BQG2 10 +Organic anion transport 0.4149120980935349 1.6700947157868875 0.0949006254803086 1.0 0.3034402165039168 41 P14174,P53007,Q9H2D1,P07602,Q9UBX3 5 +Regulation of mast cell activation involved in immune response 0.751244041041936 1.6688367835113664 0.0951497307112303 1.0 0.3036416345337355 4 P09601 1 +Regulation of mast cell activation 0.751244041041936 1.6688367835113664 0.0951497307112303 1.0 0.3036416345337355 4 P09601 1 +Dicarboxylic acid transport 0.577664672902736 1.6681690086197722 0.0952821811927935 1.0 0.3036467610848875 15 Q9H2D1 1 +Negative regulation of gluconeogenesis 0.750437508588379 1.6653901097330976 0.0958349513102789 1.0 0.3036467610848875 4 Q13043 1 +Small molecule biosynthetic process 0.3236465159696782 1.6636532061951383 0.0961817525868871 1.0 0.303815158461774 151 Q05682,Q09472,O15269,O60568,P34897,Q96C36,Q15125,P04062,P54619,Q96SU4,P00374,Q15800,Q15392,Q9NRG1,Q13043,P37268,Q9H7Z7,A1L0T0,Q13907,Q96GX9,P54646,Q16850,Q96PU8,Q13126,P55263,P14174,P00367,Q9UBX3,Q4G176,P53007,Q8NCG7,P29373,Q15126,Q53GQ0,Q9Y4C1 35 +Negative regulation of cytokine production involved in inflammatory response 0.6849361028875518 1.6620678257200328 0.0964991758154627 1.0 0.3042288025950289 3 Q06481 1 +Cell proliferation in forebrain 0.7491283268869093 1.6597937870663453 0.096955944054538 1.0 0.3052860605315041 4 Q9UIS9 1 +Cellular carbohydrate catabolic process 0.5396652907430333 1.659368505278516 0.0970415586562727 1.0 0.305348703852862 18 Q14108,Q9NUJ1 2 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.6189907435055104 1.6531410630999528 0.098302157892594 1.0 0.3082748113440982 2 Q01664 1 +Pinocytosis 0.6819694290724907 1.6505415726940844 0.0988322177673208 1.0 0.3093424715345497 8 Q9P2R3,Q06481,P50897 3 +Glial cell proliferation 0.7209132126825075 1.6455255849932728 0.0998614709348291 1.0 0.3119655142751052 6 P04062,Q96G23 2 +Negative regulation of smooth muscle cell differentiation 0.6810035842293833 1.643725082750163 0.1002330024014614 1.0 0.3129763510392046 3 Q53EL6,P51608 2 +Leukocyte proliferation 0.4261761578257337 1.640421944047502 0.1009174657677109 1.0 0.3139120026692478 37 P14174,P09429,P62753,P04062,Q12959 5 +Cell cell recognition 0.58374005956932 1.6354930366594929 0.1019457332388471 1.0 0.3162864698516735 14 Q12959,P45880,Q14157 3 +Sulfur compound transport 0.6631408975505416 1.6323785541052531 0.1025997640967677 1.0 0.3176309584893294 9 Q70HW3 1 +Intracellular distribution of mitochondria 0.6783899165324645 1.6315227159926695 0.1027800706539889 1.0 0.3177369687768508 3 O75153 1 +Deoxyribonucleoside triphosphate metabolic process 0.6773633456587428 1.6285569229029884 0.103406849717472 1.0 0.31937203088321 8 P04818,P55263,Q9H773 3 +Mitophagy 0.5696874482079208 1.6213034386722722 0.1049525779298674 1.0 0.3229233963084936 15 P49815,P12235,Q9UBN7,P21796,O95140,Q16543,Q99623 7 +Necroptotic signaling pathway 0.6118244252015549 1.616353304491561 0.1060179481220822 1.0 0.3249756361882321 2 P49327 1 +Positive regulation of response to oxidative stress 0.6118244252015499 1.6163533044915344 0.1060179481220879 1.0 0.3249756361882321 2 Q9UBN7 1 +Positive regulation of response to reactive oxygen species 0.6118244252015499 1.6163533044915344 0.1060179481220879 1.0 0.3249756361882321 2 Q9UBN7 1 +Estrogen biosynthetic process 0.6747641483939026 1.614580778391182 0.1064015107679976 1.0 0.3258452647920941 3 Q53GQ0 1 +Regulation of release of cytochrome c from mitochondria 0.6741105508381846 1.613013475129237 0.1067415802590932 1.0 0.3264271568748089 8 O00429,O60313,O14737,Q96A26 4 +Anterograde neuronal dense core vesicle transport 0.6094356524335651 1.604073613442379 0.1086978273424019 1.0 0.3314941016390269 2 P33176 1 +Dense core granule transport 0.6094356524335651 1.604073613442379 0.1086978273424019 1.0 0.3314941016390269 2 P33176 1 +Positive regulation of protein deubiquitination 0.6720430107526805 1.6018551862463617 0.1091876362297137 1.0 0.332660370697998 3 Q9NZM5,Q15020 2 +Negative regulation of ion transmembrane transport 0.5422232158716999 1.5985229696566696 0.1099266376411385 1.0 0.3339763674329934 17 P21796 1 +Chloride transport 0.6403798584812463 1.5951636686478032 0.1106756408602653 1.0 0.3348489718377802 10 Q9UHG3 1 +Astral microtubule organization 0.7216690929331568 1.5939681287948635 0.110943173521961 1.0 0.3352155725192227 5 Q12959 1 +Pyrimidine nucleotide catabolic process 0.6698896593940742 1.5917785902934871 0.1114344623774954 1.0 0.3365207318257914 3 Q9H773 1 +Rhythmic process 0.3668044571255199 1.59121549679209 0.111561086488169 1.0 0.3365916090715633 64 Q09472,P43490,P04818,Q15233,Q14103,P42345,P54646,O94813,Q13185,O14744,Q00839,O00429,Q8WXF1,P23246,Q9UNS1,P62136,Q9BQG2,Q06210 18 +Positive regulation of macroautophagy 0.4819663224300877 1.5899942652835657 0.1118360976981636 1.0 0.3369540044220755 24 Q86YR5,O15269,P48426,P09601,P54646,P12235,P27361,P21796 8 +Water homeostasis 0.6222475744240684 1.5818463475655122 0.1136846515454554 1.0 0.3412631260283544 11 Q96PU5,P16949,P04062,P17252 4 +Positive regulation of cellular amide metabolic process 0.3703905777616909 1.5802490604080803 0.1140498404725809 1.0 0.3420446961967202 59 O95900,Q7Z739,P67809,Q14103,P42345,P08670,P61254,Q567V2,Q00839,Q13144,P51116,Q92552,Q9H074 13 +Dna catabolic process endonucleolytic 0.6867145634022991 1.579198497292399 0.114290534542444 1.0 0.3422946436089904 7 Q9Y2C4 1 +Adipose tissue development 0.636997958328772 1.5779999574841417 0.114565619571018 1.0 0.3423797464027163 10 O15173,P43490 2 +Positive regulation of cell cycle checkpoint 0.7177978259037605 1.5769903027216583 0.1147977564051068 1.0 0.3423995239029831 5 Q5JVF3,P12270,Q13257 3 +Dna catabolic process 0.6658331434128328 1.5733960191432643 0.1156271482084012 1.0 0.3444010813363882 8 Q9Y2C4 1 +Regulation of protein neddylation 0.7286353246625147 1.5719493685167203 0.1159622938959823 1.0 0.3450843273895033 4 Q9BTE7 1 +Positive regulation of protein catabolic process 0.3620679517058795 1.5711841814439715 0.1161398733190206 1.0 0.3454552476207514 68 P35241,Q9P0J0,P15311,Q96PU5,Q9UKS6,Q6ZXV5,P04062,P26038,Q8NEZ5 9 +Intermediate filament based process 0.6343027743338785 1.5643096571618509 0.1177448653032802 1.0 0.3491153979869181 10 P08670,P07197 2 +Regulation of autophagy 0.3478714281631873 1.5604646045515966 0.1186501281377403 1.0 0.35095739436211 103 Q09472,Q86YR5,O15269,Q9H2M9,Q93050,P04062,P21796,Q8IYI6,Q9Y487,Q92993,P07602,Q9Y5K8,P42345,P09601,P54646,Q9Y2S7,Q9NWH9,O94874,P48426,O00429,Q9UPT5,P17252,Q9NNW5,Q08379,Q9UNH7,P09429,P14373,P12235,P27361 29 +Sensory perception 0.422861277376455 1.5558420471532055 0.1197456568911601 1.0 0.3528369076205005 35 O75695,Q9Y5L4,P50897,Q14108,Q00169 5 +Ribosome disassembly 0.7007524075238803 1.5552538118673185 0.1198856328942268 1.0 0.3528369076205005 6 Q9ULC4 1 +Nucleotide transmembrane transport 0.6474716236894393 1.5552117655122752 0.1198956431168696 1.0 0.3528369076205005 9 Q9H2D1,Q9BSK2 2 +Regulation of intracellular estrogen receptor signaling pathway 0.5352379723986869 1.5551037003894017 0.1199213738185245 1.0 0.3528369076205005 17 Q15648,O94874,P61960,Q16512,P09874,Q99623,Q9GZZ9,Q96HY6,Q9NUQ7 9 +Placenta development 0.4844395256912201 1.5536854336003132 0.1202594693067475 1.0 0.3533189217870012 23 Q13043,P35613 2 +Myeloid cell homeostasis 0.3971800814427244 1.5535176479920858 0.1202995164282434 1.0 0.3533189217870012 44 P18074,Q00534,Q15648,P26583,O94874,P09429,P09601,P62753,Q99873,Q6NYC1,Q96JB5,Q9GZZ9 12 +Dna double strand break processing 0.6999843397397647 1.5518059056961424 0.1207086724441346 1.0 0.3541364705665873 6 P51530,P54132 2 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.72333432925006 1.5491578169176696 0.1213437870724063 1.0 0.3541364705665873 4 Q5JVF3,Q13257,P12270 3 +Pyramidal neuron development 0.6606929510155232 1.5486833374106137 0.1214578613292216 1.0 0.3541364705665873 3 Q6P3W7,Q02218 2 +I kappab phosphorylation 0.680090092523018 1.5484941074162404 0.1215033793500874 1.0 0.3541364705665873 7 O15111,Q8IUD2 2 +T cell mediated cytotoxicity 0.6790467427290707 1.543653745309398 0.1226722373984314 1.0 0.3545434106564055 7 Q9BY67,P51159 2 +Negative regulation of cellular senescence 0.6592484968234962 1.5419064373679514 0.1230963314206354 1.0 0.3549018169421905 3 P67809 1 +Purine deoxyribonucleotide catabolic process 0.6591357842453126 1.5413775375114882 0.1232249276848036 1.0 0.3549018169421905 3 Q96DE0 1 +Asymmetric cell division 0.6784651930021681 1.5409552827732624 0.1233276696325318 1.0 0.3549018169421905 7 P61160,Q92974,Q08379 3 +Aspartate family amino acid biosynthetic process 0.5986150915475452 1.5399952092004818 0.123561521209623 1.0 0.3553823214693697 12 Q13126,O60568 2 +Positive regulation of endocytosis 0.5081456766106549 1.535140414083345 0.1247493409785129 1.0 0.3573811234529305 19 Q96PU5,P50897,Q6P3W7,Q9P2R3,Q06481 5 +Pyrimidine deoxyribonucleoside triphosphate metabolic process 0.7197315095633348 1.5336531245869136 0.1251150114810819 1.0 0.3581142828620793 4 Q9H773 1 +Methionine biosynthetic process 0.7074313276067625 1.531453579064722 0.1256573308493875 1.0 0.359200563959215 5 Q13126 1 +Sulfur amino acid biosynthetic process 0.7074313276067625 1.531453579064722 0.1256573308493875 1.0 0.359200563959215 5 Q13126 1 +Intermediate filament organization 0.7070717935781587 1.5298724515012905 0.1260483035246489 1.0 0.3596813418460248 5 P08670 1 +Lens development in camera type eye 0.6759253837713391 1.5291660764302784 0.126223278058811 1.0 0.3600232135541088 7 Q12959,P08670,Q15648,P35240 4 +Phosphatidylcholine biosynthetic process 0.6563559306497555 1.5279312710178123 0.1265296031367238 1.0 0.3607392704544602 8 Q6IAN0 1 +Establishment of centrosome localization 0.6938629074275575 1.524305533163743 0.1274324056052678 1.0 0.3628376435340217 6 Q12959 1 +Deoxyribose phosphate metabolic process 0.5643564184311023 1.523979079491704 0.1275139372981377 1.0 0.3629114499815294 14 P04818,P13051,Q9H773,Q96DE0,P55263 5 +Collagen metabolic process 0.6262320979839529 1.523255166980004 0.1276948789568934 1.0 0.3631097080926739 10 Q32P28,P08670,O60568 3 +Mammary gland duct morphogenesis 0.6550883419875597 1.5223766788473512 0.1279147248733252 1.0 0.3634181517297868 3 Q15648 1 +G quadruplex dna unwinding 0.7043656080712579 1.5179677575588626 0.129022526988962 1.0 0.3656105128658123 5 P51530,P54132 2 +Regulation of microtubule based movement 0.7018422546931411 1.5068616794603138 0.1318461156711157 1.0 0.3681852300685041 5 P57076 1 +Mesenchyme morphogenesis 0.6512223368018343 1.504213005582843 0.1325265300837423 1.0 0.3686564941715697 3 Q13485 1 +Walking behavior 0.651135005973707 1.5038025415625584 0.1326322165918285 1.0 0.3687932873788978 3 O75844,O15118 2 +Arachidonic acid metabolic process 0.6879988592664773 1.4979286226916315 0.1341517961975653 1.0 0.3720674126584409 6 Q9H7Z7,P07099 2 +Dna damage induced protein phosphorylation 0.6497040777703413 1.4970760729124308 0.1343734648352206 1.0 0.3723657034032482 3 O14757 1 +Positive regulation of cell migration by vascular endothelial growth factor signaling pathway 0.5882352941176507 1.4947630932062783 0.1349762815000974 1.0 0.3735603108861899 2 P04792 1 +Cellular monovalent inorganic cation homeostasis 0.4484298783427436 1.494355750969247 0.1350826605259616 1.0 0.37369624527021 27 Q96PU5,Q93050,P50897,Q92544 4 +Histone serine phosphorylation 0.7104196300952477 1.49352974609078 0.1352985738164298 1.0 0.3738486578445777 4 Q13043 1 +Lipoprotein catabolic process 0.6870121880026757 1.4934875443067828 0.1353096122937316 1.0 0.3738486578445777 6 Q9NUJ1 1 +Biological process involved in intraspecies interaction between organisms 0.7096638246565048 1.4902701631922268 0.1361532143685138 1.0 0.3753848233920241 4 P51608,Q9UIS9 2 +Membrane lipid metabolic process 0.4283928471017728 1.4891314001937144 0.1364527706646545 1.0 0.3760518502354458 31 P07602,Q8NBX0,P04062,Q96G23 4 +Neuron projection maintenance 0.5870409077336556 1.4885894116745022 0.1365955215180854 1.0 0.3761627848969653 2 Q14203 1 +Positive regulation of helicase activity 0.6976822742132347 1.4885408963552194 0.1366083052721127 1.0 0.3761627848969653 5 Q9Y3Y2,Q04837,P20585 3 +Regulation of cell shape 0.4281327663532241 1.4869371686102906 0.1370314063485695 1.0 0.3768508039741952 31 P35241,Q16181,P35580,Q9Y2J2,P15311,P26038,Q96AC1,Q14344,Q9UQB8,P35579,O75844,P63000,Q7KZI7,Q12959 14 +Production of sirna involved in rna interference 0.6472520908004693 1.4855457530049758 0.137399312850093 1.0 0.3775443855409292 3 O75569,Q15631 2 +Regulation of protein folding 0.7083438232985804 1.484576364498519 0.1376560803452815 1.0 0.3779316703127082 4 Q9H2J4 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4814693201265362 1.4829810859641923 0.1380794360569899 1.0 0.3788513075220226 22 Q9Y282,P24390 2 +Megakaryocyte development 0.6962650382701239 1.4822962158987494 0.1382614947494147 1.0 0.3788513075220226 5 Q09472,Q15648 2 +Cytoplasm organization 0.7077980280848257 1.4822217250272447 0.1382813077715994 1.0 0.3788513075220226 4 Q9Y2W6,P33176,Q9NYV6 3 +Interleukin 2 production 0.6024950029420791 1.4781584082100596 0.1393653834776871 1.0 0.3811372566732611 11 P15311,Q9UJZ1,Q92993,P14373 4 +Negative regulation of tumor necrosis factor mediated signaling pathway 0.5849507315616641 1.4777821409143796 0.1394661000514476 1.0 0.3811372566732611 2 Q8N2W9 1 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.6951540735264492 1.4773999826239743 0.1395684508257391 1.0 0.3812573085344384 5 Q5JVF3,P12270,Q13257 3 +Positive regulation of stem cell differentiation 0.7057559013947964 1.4734098567266225 0.140640554075575 1.0 0.3830911715229703 4 Q9Y6C9,Q13610 2 +Cellular metabolic compound salvage 0.586033057921459 1.4717175102760542 0.1410971771020084 1.0 0.3835069461756381 12 P55263,Q13126,Q96GX9 3 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.6937525968708548 1.4712221152792753 0.1412310582394065 1.0 0.3835513466793037 5 Q9UBN7,Q16543,O95140 3 +T cell differentiation in thymus 0.5705782770889423 1.470632076812019 0.1413906442673242 1.0 0.3835769488493765 13 O96005,P04062,Q00534,P62753 4 +Microtubule nucleation 0.5439636497494077 1.4692922346299082 0.141753542148648 1.0 0.3835769488493765 15 Q08379,O75122,Q9BSJ2,P23258,Q16512,Q99996 6 +T cell mediated immunity 0.5701164614180888 1.46804367727407 0.1420923590978031 1.0 0.3841320362354032 13 Q9BY67,O15400,P09429,P51159 4 +Nadh dehydrogenase complex assembly 0.4575070167892192 1.465677895874739 0.1427360587766248 1.0 0.3856972527588279 25 Q9P0J0,P51970,O43676,Q86Y39,Q9H061,O75306 6 +Negative regulation of g protein coupled receptor signaling pathway 0.6924506422692239 1.4654816919407652 0.1427895437734183 1.0 0.3856972527588279 5 P16949,P50570 2 +Regulation of regulated secretory pathway 0.4789409657515504 1.4652222067893004 0.1428603027894868 1.0 0.385728728177158 22 P51159,P09601,Q9UJ41,P16615,Q4J6C6 5 +Positive regulation of lymphocyte differentiation 0.6138509395729085 1.4601189781077333 0.1442573776521201 1.0 0.3884386986174 10 Q5JVF3 1 +Glycolipid biosynthetic process 0.6901432632470182 1.4553053888521472 0.1455847354408979 1.0 0.3909818862087653 5 Q96S52,Q92643,Q8NBX0 3 +Inflammatory response 0.3408305340697899 1.4518738867803351 0.1465366746168275 1.0 0.3924080174597523 79 P14174,Q9Y263,Q9UNH7,O15111,Q8NCG7,P26583,P09429,P09601,Q6IAN0,Q8IV08,Q9UJ41,P42785,P04062,Q06481 14 +Sterol biosynthetic process 0.4429512039446423 1.4513532080085307 0.146681532189917 1.0 0.392634815041591 27 P37268,Q13907,Q15125,Q15126,Q16850,Q14534,Q15800,Q15392 8 +Polyol biosynthetic process 0.581709577457032 1.4482086627225852 0.1475587026112568 1.0 0.3948208664374997 12 P04062 1 +Long chain fatty acid metabolic process 0.4550967500954636 1.4475415385070982 0.1477453112854614 1.0 0.3949962726132409 25 Q96PU8,Q9H7Z7,P07099 3 +Insulin receptor signaling pathway 0.4317518527684417 1.4466103597348692 0.1480060830517746 1.0 0.3953308500753716 29 P43490 1 +Regulation of protein localization to nucleolus 0.6759665452417829 1.443717816857468 0.1488183675843672 1.0 0.396727396591332 6 Q96EZ8,Q96BK5 2 +Mitochondrial protein processing 0.6757868720296866 1.4429075062735666 0.1490465283672617 1.0 0.3971063621394631 6 Q9UJZ1,Q10713,Q96TA2 3 +Positive regulation of response to biotic stimulus 0.3982953949519885 1.4426029538615066 0.1491323508082196 1.0 0.3971063621394631 39 Q09472,P14174,Q15648,Q15233,Q9BY67,P26583,P09429,Q8WXF1,P17252,Q9NUD5 10 +Folic acid containing compound catabolic process 0.5780830098536847 1.4422452033756603 0.1492332125633679 1.0 0.3971843169610682 2 Q9NRN7 1 +Negative regulation of signaling receptor activity 0.656823643534933 1.4403050208995989 0.1497811215275253 1.0 0.3982238253371863 7 Q99816,Q86XI2,P30533,Q9UNH7 4 +Post translational protein modification 0.5496668596681745 1.4390409681212104 0.1501389156993764 1.0 0.3984671088083595 14 Q32P28 1 +Secondary alcohol metabolic process 0.391037622828693 1.4390279567846 0.1501426019858651 1.0 0.3984671088083595 41 P37268,Q13907,Q15125,Q15126,P04062,Q16850,Q15036,Q14534,Q8WTV0,Q15800,Q15392 11 +Positive chemotaxis 0.6373558123256672 1.4364962234165255 0.1508611902128991 1.0 0.3998138722177751 8 P26583,P14174,P09429 3 +Histone arginine methylation 0.6365072821935029 1.4349641578145538 0.1512973114762128 1.0 0.4005868510468432 3 Q99873 1 +Microtubule polymerization 0.412762126908042 1.4347056118125705 0.1513710043949609 1.0 0.4005868510468432 34 P16949,Q08379,O75122,P30622,Q9Y295,P04350,P23258,Q16512,Q99996,Q9BSJ2,Q9NWH9,P63000 12 +Positive regulation of multicellular organism growth 0.6850739204953353 1.4329357741142952 0.1518761925887615 1.0 0.4013334537022084 5 P15311,Q14651 2 +Activation of immune response 0.367216096511609 1.4328555725846752 0.1518991159430669 1.0 0.4013334537022084 52 Q09472,P46379,Q13177,P19174,Q15233,P15311,Q9NR50,P09429,Q9UJ41,Q9NUD5,Q8WXF1,Q13144,Q06481,Q16512,Q99623,Q9UJZ1 16 +Negative regulation of microtubule polymerization 0.6843868640146231 1.42990277958644 0.1527449241566465 1.0 0.4030785988864842 5 P16949 1 +Protein neddylation 0.6541255209701416 1.4277293992086697 0.1533697607443735 1.0 0.4044004277243564 7 Q9BTE7 1 +Regulation of amyloid beta clearance 0.6838437537875511 1.4275050399766005 0.1534343734884828 1.0 0.4044073995904035 5 Q16850,P30533 2 +Calcium ion import 0.5776831478904638 1.426296249841214 0.1537828466568522 1.0 0.4049987317524688 12 P21796,P16615,P14373 3 +Regulation of response to biotic stimulus 0.3466917862176342 1.4250464919393968 0.1541437623588726 1.0 0.4057854752537324 72 Q09472,Q7Z739,Q15648,Q15233,Q9BY67,Q9NZM5,Q3LXA3,Q16512,O75844,Q13177,P26583,Q8WXF1,Q16543,Q15366,Q8TAT6,P14174,Q8TDB6,Q06481,Q14166,P17252,P09429,P27361,Q9NUD5 23 +Cilium movement 0.6344163398740754 1.4223221203250918 0.1549327601674801 1.0 0.4065505399489246 8 P57076,Q86Y56 2 +Leukocyte migration 0.377592537143994 1.4199404078216185 0.155625030754352 1.0 0.407472921290621 47 P14174,P09429,P09601,Q9UJ41,O00429,P04062,P35613,P26038 8 +Fatty acid derivative biosynthetic process 0.5462932365356358 1.419491801436458 0.1557556854069526 1.0 0.4075627918868375 14 Q4G176,P53007 2 +Vacuolar acidification 0.6198897399110819 1.4186604366743496 0.1559980368224123 1.0 0.4078698671085988 9 Q9Y487,Q93050,P50897 3 +Regulation of nitric oxide synthase activity 0.6502223649866148 1.4095286450392837 0.1586789094447795 1.0 0.4110257808576409 7 Q8WTV0 1 +Leukocyte apoptotic process 0.500526400275531 1.4088184922124292 0.158888845669078 1.0 0.4110257808576409 18 P24390,P14174 2 +Monovalent inorganic cation homeostasis 0.4185274600873107 1.405765981051637 0.1597936268908988 1.0 0.413158957642633 31 Q96PU5,Q93050,P50897,Q92544 4 +Sensory perception of light stimulus 0.5220066600820336 1.4033449682990211 0.1605139948016325 1.0 0.4142010004252487 16 O75695,Q6P4Q7,O60313,P50897,O75569,Q00169 6 +Odontogenesis of dentin containing tooth 0.6478911114226517 1.398653346103328 0.1619169608727477 1.0 0.4168323813236891 7 Q6P4Q7,P35613,P35240 3 +Activated t cell proliferation 0.6766949945478418 1.3959298763953314 0.1627356127969816 1.0 0.4181152004382292 5 P09429 1 +Action potential 0.4616723838899674 1.3902438332710214 0.16445484710083 1.0 0.4204751020926901 23 Q96PU5,Q99996,P04062,Q12959 4 +Fatty acyl coa biosynthetic process 0.600117770051969 1.3899102051708785 0.1645561462986102 1.0 0.4204751020926901 10 Q4G176,P53007 2 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.6247393815268694 1.3794847660690357 0.1677453399961732 1.0 0.4259556765817224 3 P62081 1 +Negative regulation of anion transport 0.5646461630337433 1.3726213506752842 0.1698700909133266 1.0 0.4285677639802494 2 Q9HD26 1 +Negative regulation of anion transmembrane transport 0.5646461630337433 1.3726213506752842 0.1698700909133266 1.0 0.4285677639802494 2 Q9HD26 1 +Protein targeting to peroxisome 0.6714064705989102 1.3725560322189625 0.1698904084304175 1.0 0.4285677639802494 5 O75381,P50542 2 +Negative regulation of leukocyte migration 0.6419639607230674 1.370990064715158 0.1703780532023673 1.0 0.4289863693490573 7 P14174,P09601 2 +Macroautophagy 0.3329867321105249 1.3682863504705451 0.1712224615967015 1.0 0.4299337377376199 109 Q96AX1,Q86YR5,O15269,Q9H2M9,Q93050,Q8WUX9,Q9UNZ2,P04062,P21796,Q99623,Q9Y487,Q96HY6,Q9H267,Q9Y263,Q9Y5K8,P42345,P09601,P54646,Q99816,Q9Y2S7,O94874,P48426,Q9UPT5,Q9Y2L5,P17252,Q9GZZ9,Q9UNH7,P12235,P27361,P61960,P16615 31 +Negative regulation of smooth muscle cell migration 0.6702427050489962 1.367411072235177 0.171496493749552 1.0 0.430073478024023 5 Q9BR76,P27695,Q14344 3 +Regulation of hormone metabolic process 0.6697944974451777 1.3654294418130506 0.1721181155439359 1.0 0.4310218043130184 5 P16435 1 +Hematopoietic stem cell proliferation 0.6694078916726038 1.3637201145134263 0.1726556709145381 1.0 0.4320363912531733 5 P04062,O95376 2 +Regulation of mitophagy 0.6402052510253037 1.3627786166447493 0.1729522922459834 1.0 0.4324469958610298 7 P21796 1 +Biomineralization 0.5348740838017737 1.3532301889443858 0.1759821036584019 1.0 0.4378204492104751 14 P18074,Q9NUQ3,Q13464,Q6P4Q7,O75116,Q4KMQ2,O75844,Q9UBB9 8 +Establishment of epithelial cell apical basal polarity 0.6381577175091429 1.3532170754493376 0.1759862917426289 1.0 0.4378204492104751 7 P15311 1 +Methionine metabolic process 0.655601631070582 1.3517595118919363 0.1764522602042499 1.0 0.4382380278679418 6 Q13126 1 +Extrinsic apoptotic signaling pathway via death domain receptors 0.5023633021677971 1.3495173584326638 0.177170848636921 1.0 0.4384600623180096 17 Q9NR28,Q9H0S4,Q13043,P26583,P09601 5 +Secretory granule localization 0.6181941867393062 1.348602691794267 0.1774646156173576 1.0 0.4384980879707232 3 O60763 1 +B cell receptor signaling pathway 0.5589728277097662 1.3431999437475026 0.1792072398859145 1.0 0.4416161385227712 2 P28482 1 +Protein processing involved in protein targeting to mitochondrion 0.6169611835972404 1.3427837340513078 0.1793420118673645 1.0 0.4416550828099701 3 Q10713 1 +Positive regulation of cellular protein catabolic process 0.3678732591034189 1.34209550583867 0.1795650308928578 1.0 0.441943330151768 48 P35241,O95376,P15311,Q9NZM5,P51572,Q6ZXV5,P04062,P54725,Q96JB5,P26038,Q8NEZ5,Q96HY6 12 +Positive regulation of monooxygenase activity 0.6643848828200378 1.3415075641580625 0.1797557154900602 1.0 0.4420067065893492 5 Q8WTV0 1 +Snrna transcription by rna polymerase ii 0.664059076963361 1.3400665752019216 0.1802237016230932 1.0 0.4426570857328966 5 Q659A1,P55199,Q6P1N0 3 +Snrna transcription 0.664059076963361 1.3400665752019216 0.1802237016230932 1.0 0.4426570857328966 5 Q659A1,P55199,Q6P1N0 3 +Mitochondrial trna processing 0.6637433166930997 1.3386699940141389 0.1806781287351651 1.0 0.4434467477174587 5 O15091 1 +Phospholipid transport 0.5322570872062165 1.3380285455995893 0.1808871316177096 1.0 0.4437854965929222 14 Q14108,P08183,Q8WTV0 3 +Regulation of cytoplasmic translation 0.5468614591191587 1.3374023948883138 0.1810913231455899 1.0 0.4439526577190533 13 P67809,O60506,Q14103,P42345,Q00839,Q9H074 6 +Basement membrane assembly 0.6736051870670243 1.3343881962348645 0.1820766664484541 1.0 0.44569854660263 4 O60568 1 +Negative regulation of stress activated protein kinase signaling cascade 0.5891478296146748 1.3337319807414392 0.1822917098192837 1.0 0.445890441634425 10 Q12959 1 +Water soluble vitamin metabolic process 0.4602425240257892 1.33350873072605 0.1823649123000796 1.0 0.4459023670551967 22 Q9H2D1 1 +Establishment of protein localization to endoplasmic reticulum 0.4662780815121548 1.3328858014887026 0.1825692827163512 1.0 0.4460986366339332 21 O43681,Q9H2M9,P09132,O76094,Q9UHB9,P49458,Q7L5D6,P33908,Q9Y5M8 9 +Protein poly adp ribosylation 0.614787734360798 1.3325257789773917 0.1826874761854886 1.0 0.4461625844763846 3 P09874 1 +Endothelial cell apoptotic process 0.6730761784178027 1.3320977601689226 0.1828280662718313 1.0 0.4461625844763846 4 Q4KMQ2,P19174 2 +Negative regulation of leukocyte mediated immunity 0.661944352147082 1.3307129358196417 0.1832834849627804 1.0 0.446723767192852 5 P09601 1 +Regulation of cardiac conduction 0.6619213871680161 1.3306113546924478 0.1833169243859114 1.0 0.446723767192852 5 P16615 1 +Positive regulation of autophagy 0.3950321770734387 1.3298537522474918 0.1835664616132193 1.0 0.4469980330178617 36 Q86YR5,O15269,Q9H2M9,O94874,P48426,P09429,P09601,P54646,P14373,P12235,P27361,P21796,Q92993 13 +Regulation of potassium ion transmembrane transporter activity 0.5594002205129145 1.3266201847401735 0.18463435539168 1.0 0.4491978847948341 12 Q96PU5,Q99996,Q12959 3 +Actin filament based transport 0.6315081160771806 1.3221553867983042 0.186116413491268 1.0 0.4513547805440414 7 Q9Y4I1,O43707,Q8WXH0 3 +Regulation of receptor signaling pathway via stat 0.6110647855075291 1.3095437255321942 0.1903502364213454 1.0 0.4587411694317852 8 P35240,Q13043 2 +Reticulophagy 0.6460833010696633 1.308725918245279 0.1906272089687921 1.0 0.4592222833999031 6 O94874,Q9GZZ9,Q96HY6,P61960 4 +Negative regulation of transmembrane transport 0.4562342865329502 1.3052092116109577 0.1918216183729877 1.0 0.4619291075653571 22 Q96PU5,P21796 2 +Organism emergence from protective structure 0.6665684439226369 1.3039187609361091 0.1922612828552012 1.0 0.4625653577125113 4 Q8IWS0 1 +Udp n acetylglucosamine biosynthetic process 0.608515332927106 1.302919124552641 0.1926023740253293 1.0 0.4629550986700917 3 Q06210 1 +Peroxisomal transport 0.6443124625342203 1.3007180731433998 0.1933549736608861 1.0 0.4635817665273392 6 O75381,P40855,P50542 3 +Flavin containing compound metabolic process 0.6080457167189102 1.3007024060083974 0.1933603384136404 1.0 0.4635817665273392 3 Q8NFF5 1 +Negative regulation of exocytosis 0.6088642783999574 1.2989059994663903 0.193976190515472 1.0 0.4645462823133836 8 P09601 1 +Protein polymerization 0.3286341793524029 1.2982995194071143 0.1941844314907175 1.0 0.4648743946839407 82 Q9Y2A7,Q9UQB8,Q16512,P04350,P23258,Q99996,Q12959,P45880,P52907,P42345,P47755,Q16763,Q96F07,Q9NWH9,O00429,P35241,P16949,Q08379,O75122,P30622,Q9Y295,P59998,Q9BSJ2,P51608,P63000,Q13813 26 +Regulation of stem cell proliferation 0.6262341628959961 1.297512612312416 0.1944548683851126 1.0 0.4653511078405739 7 Q00839,P26583,O95251,P35240 4 +Activation of innate immune response 0.4418678222654315 1.2952731090068887 0.1952260322963934 1.0 0.4666831819656643 24 Q09472,Q13177,Q15233,P09429,Q8WXF1,Q16512,Q9NUD5 7 +Process utilizing autophagic mechanism 0.2882130489256934 1.2946736025212675 0.1954328499395812 1.0 0.4666849085278375 169 Q96AX1,Q09472,Q86YR5,O15269,Q9H2M9,Q93050,Q8WUX9,Q9UNZ2,P04062,P21796,Q8IYI6,Q99623,Q9Y487,Q92993,Q96HY6,Q9H267,Q9Y263,P07602,Q9Y5K8,P42345,P09601,P54646,Q99816,Q9Y2S7,P27695,Q7KZI7,Q9NWH9,O94874,P48426,O00429,Q9UPT5,Q9Y2L5,P17252,Q9GZZ9,Q9NNW5,Q08379,Q9UNH7,P09429,P14373,P12235,P27361,P61960,P16615 43 +Amide transport 0.393686653620277 1.2946491485969809 0.1954412894585626 1.0 0.4666849085278375 35 Q9H2D1,P07602,P08183,P53985 4 +Mitochondrial atp synthesis coupled proton transport 0.5675019827795794 1.2934844120401672 0.195843571918467 1.0 0.4673381323634723 11 P18859,P06576,P56134,O75964,P25705,Q9UJZ1 6 +Response to dexamethasone 0.5947000370376919 1.2934424561475113 0.195858074167039 1.0 0.4673381323634723 9 P16435,P04062,P25705,Q01664 4 +Microtubule organizing center localization 0.5039799674776453 1.2931740106922285 0.1959508822097622 1.0 0.4673886905339576 16 P15311,Q13257,O43237,Q8WXH0,Q99996,Q9NVM9,Q12959 7 +Cation transmembrane transport 0.3263921994629962 1.290826242449512 0.1967639358694826 1.0 0.4689851882703592 113 Q70HW3,P35754,Q93034,O75964,P50570,P21796,Q99996,Q99623,Q12959,Q9HD20,Q9HC21,P27695,Q96PU5,P06576,Q9UDW1,P56134,P17252,Q9UJZ1,Q9UM00,P18859,P46939,P14854,P12235,P16615 24 +Extracellular matrix assembly 0.6515569817241964 1.2847605622522678 0.1988759676651219 1.0 0.4725324704209735 5 O60568 1 +Regulation of action potential 0.5658388425583689 1.2846909062243916 0.1989003173226069 1.0 0.4725324704209735 11 Q99996,P04062,Q12959 3 +Oxidative phosphorylation 0.343942967708063 1.2809767132930647 0.2002018455523526 1.0 0.4745794566199249 60 P18859,O43678,O75323,P51970,P34897,P06576,O75380,O43676,Q9UDW1,O75964,P22695,P56134,Q9BSK2,Q9UJZ1,O75306 15 +Deoxyribose phosphate catabolic process 0.6212885209554495 1.2744015804634157 0.2025211325010738 1.0 0.4779938194220643 7 P13051,Q96DE0,Q9H773 3 +Maintenance of dna repeat elements 0.6596898391834114 1.2741327839621222 0.2026163615295173 1.0 0.4780456888436841 4 O75844,P20585 2 +Lipid biosynthetic process 0.3041067670913684 1.2734213060129551 0.2028685808694088 1.0 0.4784677841538713 147 O15269,Q15648,Q6IAN0,Q15125,P04062,P54619,P35790,Q96SU4,Q8NBX0,Q8WTV0,Q15800,Q15392,Q6UWP7,P37268,P16435,P42345,Q9H7Z7,P54646,Q13907,Q16850,Q96PU8,Q92643,Q10713,P42356,P14174,P28288,P48426,Q08AM6,P48651,Q4G176,Q14534,Q96G23,Q8NCG7,P29373,Q86TV6,Q9UBF8,Q06136,Q15126,Q53GQ0,Q96N66,Q01968 41 +Liver regeneration 0.5771507689249995 1.2722409138744837 0.2032875348779699 1.0 0.4789366254922858 10 P09601,P62841 2 +Mrna pseudouridine synthesis 0.6482471227927478 1.2701178711066865 0.2040426466989644 1.0 0.4800224629983569 5 O95900,Q9Y606 2 +Mitochondrion distribution 0.6474324779741225 1.2665140663925696 0.2053290966268903 1.0 0.4820063613622613 5 P27695,O75153 2 +Regulation of synaptic transmission gabaergic 0.6007210328103854 1.2661302944240052 0.2054664382282711 1.0 0.4821553311318581 3 P27695 1 +Cd4 positive alpha beta t cell activation 0.6010830392754023 1.2612865672202187 0.2072056191011184 1.0 0.4841474651822051 8 P09429,Q9UJZ1 2 +Gliogenesis 0.3445687606805012 1.2597197818205104 0.2077704666469253 1.0 0.4848349794046462 56 P18074,Q00534,P35240,Q96G23,O94874,P42345,P08670,O14744,P27361,P04062,Q13144,Q96N66,O75306 13 +V d j recombination 0.599802349167601 1.2550950149523543 0.2094442699185921 1.0 0.4875740514397667 8 P26583,P09429 2 +Chloride transmembrane transport 0.64406574791169 1.2516214522521545 0.2107078339008918 1.0 0.4895262812521254 5 P51790,Q9UHG3 2 +Regulation of wound healing spreading of epidermal cells 0.6437445277679317 1.2502006539807398 0.2112262579935866 1.0 0.4900329042538736 5 P42345,Q96AC1,O75122 3 +Wound healing spreading of epidermal cells 0.6437445277679317 1.2502006539807398 0.2112262579935866 1.0 0.4900329042538736 5 P42345,Q96AC1,O75122 3 +Regulation of protein complex stability 0.643066410795453 1.247201328087268 0.2123236860764958 1.0 0.4911819834580688 5 Q9BQ95 1 +Trna transport 0.6533954356905647 1.2468811519505156 0.2124410786907296 1.0 0.4912794045130054 4 P67809 1 +Negative regulation of microtubule polymerization or depolymerization 0.4858705725901542 1.2458957652026117 0.2128026650036945 1.0 0.4915929882527823 17 P16949,O75122,O15344,Q9UBN7,Q92974,P04350 6 +Negative regulation of hormone metabolic process 0.5401612421618457 1.245632645161315 0.2128992916727523 1.0 0.4916421717821592 2 O60678 1 +Endoplasmic reticulum to golgi vesicle mediated transport 0.3401533031137885 1.2451672531986044 0.2130702770631705 1.0 0.4916890481309232 61 Q9Y282,P24390,Q08379,P51572,Q9Y3B3,P55735,Q9Y2L5,O95070,Q9P2W9 9 +Metanephric mesenchyme development 0.5959298354863263 1.2435219372042854 0.2136755622389936 1.0 0.4925002224426553 3 Q13485 1 +Kidney mesenchyme development 0.5959298354863263 1.2435219372042854 0.2136755622389936 1.0 0.4925002224426553 3 Q13485 1 +Regulation of notch signaling pathway 0.6524414074130855 1.2427514209008566 0.2139594488988589 1.0 0.49252182134531 4 Q9NWT6 1 +Regulation of snrna transcription by rna polymerase ii 0.5952807646355927 1.240459718333247 0.2148054044940099 1.0 0.4939464657251265 3 Q7L2J0,Q6P1N0 2 +Anaphase promoting complex dependent catabolic process 0.5704842810112324 1.2380663769930509 0.2156914497634101 1.0 0.4951076787740162 10 Q13618,Q9UJX5,P24941,Q9UJX4,Q16763,Q9H1A4,Q9UJX2 7 +Regulation of protein polymerization 0.3372873767262024 1.236285008646447 0.2163526415554044 1.0 0.4962802596803408 64 Q9Y2A7,Q9UQB8,Q16512,P04350,Q99996,Q12959,P45880,P52907,P42345,P47755,Q96F07,Q9NWH9,P35241,P16949,P30622,P59998,P63000,P51608,Q9Y295,Q13813 20 +Low density lipoprotein particle clearance 0.5826491046229196 1.2334820988340416 0.2173959514181143 1.0 0.497973316586386 9 Q8WTV0 1 +Cellular response to acid chemical 0.5141998570660018 1.2330523222248164 0.2175562439075506 1.0 0.498165630786202 14 Q14103,Q9UQB8 2 +Protein transport within lipid bilayer 0.5374738727978565 1.2317022921860452 0.2180603132764065 1.0 0.4991447227084633 2 Q14699 1 +Regulation of vesicle mediated transport 0.3164360431054885 1.2271898983507166 0.219751225274708 1.0 0.5017832386783571 125 Q6P3W7,P50570,P30533,Q8WTV0,Q15019,P15311,P09601,P27695,Q4J6C6,P36507,Q96PU5,Q9UKS6,Q06481,Q9P2W9,P35241,P09429,P51159,P50897,Q9UJ41,Q9P2R3,Q9UNF0,Q15036,P26038,P16615,P63000 25 +Cellular response to hyperoxia 0.5359808898178624 1.2239649793090293 0.2209654389448425 1.0 0.5042029561377771 2 P49327 1 +Long term synaptic potentiation 0.5799402291158894 1.2200066728020234 0.2224623453380279 1.0 0.5065559196357188 9 Q12846,Q9BPZ3 2 +Organic cyclic compound catabolic process 0.2764831507575466 1.2194377785432378 0.2226780784562494 1.0 0.5068702964790666 177 Q7Z739,P67809,P30519,Q9Y2C4,Q9H773,Q9BQG2,Q8WTV0,Q9NRG1,Q14103,P13051,P09601,Q00839,Q13126,P51530,P53004,Q9Y3B2,P27695,Q09161,P08670,Q9UPR3,Q9HCE1,Q5JVF3,P51116,P17252,Q969Z0,P05455,Q969T7,Q9NPI6,Q96DE0,Q15036 30 +Response to interleukin 7 0.579653031825026 1.2185781264072133 0.2230043553155622 1.0 0.5070422780603453 9 P67809,P31948 2 +Odontogenesis 0.5666763580844941 1.218548963261112 0.223015430044974 1.0 0.5070422780603453 10 P35613 1 +Toxin transport 0.5017810624965919 1.2181509384970963 0.2231666196291493 1.0 0.5070422780603453 15 Q9NVM6,Q93050 2 +Connective tissue development 0.4133507589117236 1.218038214189057 0.2232094512457267 1.0 0.5070422780603453 27 O15173,P43490,Q6IAN0,P04818 4 +Cellular response to reactive nitrogen species 0.5921304230213237 1.2180109604555318 0.2232198076719846 1.0 0.5070422780603453 8 Q14103,P50570,P24941 3 +Response to nitric oxide 0.5921304230213237 1.2180109604555318 0.2232198076719846 1.0 0.5070422780603453 8 Q14103,P50570,P24941 3 +Fatty acid biosynthetic process 0.3907171027886285 1.2141650829953523 0.2246846911311002 1.0 0.5093061112613964 33 Q96PU8,P14174,Q9H7Z7,Q4G176 4 +Neuron projection regeneration 0.5787086021285036 1.2138806451987147 0.2247933048234744 1.0 0.5093753844715259 9 P00374 1 +Positive regulation of epithelial cell apoptotic process 0.6354751158580114 1.2136338096693575 0.2248875903398364 1.0 0.5094121536125554 5 Q4KMQ2,Q53EL6,P19174 3 +Regulation of sodium proton antiporter activity 0.5887096774193437 1.2094688282456605 0.2264827797821544 1.0 0.5122609949558187 3 O43707,Q9UHD1 2 +Endothelial cell morphogenesis 0.5886009764417814 1.208956355647843 0.2266796133125361 1.0 0.5122609949558187 3 O60568 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.5375856732222467 1.207516222666141 0.2272334013217043 1.0 0.5123799876449486 12 P35221,Q13177,Q13043,O95999,Q12933,P30154,P30101,P62136,Q13546 9 +Positive regulation of ubiquitin dependent protein catabolic process 0.3951300681710586 1.2073510565316348 0.2272969758247205 1.0 0.5123799876449486 31 O95376,P51572,P04062,Q96JB5,P54725,Q8NEZ5,Q96HY6 7 +Copper ion homeostasis 0.6439542749591105 1.2060262240595567 0.2278073791452048 1.0 0.5133532307671295 4 O60826,O43819 2 +Erythrocyte homeostasis 0.3702500229622795 1.205626704315582 0.2279614577827056 1.0 0.5134514749089196 40 P18074,Q86XI2,Q00534,Q15648,P26583,O94874,O95251,P09601,P62753,Q99873,Q6NYC1,Q96JB5,Q9GZZ9 13 +Oligodendrocyte development 0.5769835461491353 1.205301295269398 0.2280870097702969 1.0 0.5134514749089196 9 P18074,Q13144,Q9NR50,Q96P11 4 +Base excision repair 0.4476160634764851 1.2037896667091152 0.2286708846120382 1.0 0.5135258750785139 21 P13051,P15927,P35244,P51530,P27695 5 +Protein k11 linked ubiquitination 0.5763592633510116 1.2021968089859365 0.2292872853629322 1.0 0.5147329976878209 9 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4 +Regulation of microtubule polymerization 0.4355240603412983 1.2015266264444773 0.2295469842898452 1.0 0.5148005351206646 23 P16949,P30622,Q9Y295,Q16512,P04350,P63000,Q99996,Q9NWH9 8 +Microtubule depolymerization 0.4682150632940249 1.2002218537528446 0.2300531901022018 1.0 0.5155656313897559 18 P16949,O75122,O15344,Q9UBN7,Q92974,O00139,P29372 7 +Positive regulation of chromosome segregation 0.5882735186009035 1.1993746212030518 0.2303823112683591 1.0 0.5158222922505911 8 Q9P258,Q99741,Q96SB8,Q8IXJ6,Q00839,Q14980 6 +In utero embryonic development 0.3227069561450053 1.1993166601628515 0.2304048393978659 1.0 0.5158222922505911 103 P67809,O43678,Q15293,Q15648,O60568,Q6GQQ9,Q14344,Q9BRT9,Q4VCS5,Q9NYV6,Q13043,Q13485,O95067,P20290,Q13503,Q9Y3Y2,Q9Y5P4,Q8IWS0,Q9NPQ8,O14757,Q99873,Q9HCS7,Q96EK5,P35579,P55199,P18074,Q86XI2,Q8TCT9,P23786,P20042,O43819,Q01968 32 +Spindle organization 0.3220166015118123 1.198839192347224 0.2305904797981706 1.0 0.516060861166962 85 Q9UQE7,Q8WUX9,P23258,O00139,Q9NVM9,Q12959,Q9BZD4,P15311,O95067,Q00839,Q9Y2S7,Q13561,Q9BV86,O43663,Q12873,P12270,Q9BW19,Q9NS87,P16949,Q08379,O75122,Q9BSJ2,Q9Y295 23 +Regulation of plasma lipoprotein particle levels 0.5219941737747983 1.1973767616469244 0.2311597370917428 1.0 0.5168470944260702 13 P17252,Q8WTV0,P09601 3 +Microtubule polymerization or depolymerization 0.3539475531358139 1.1957694979971518 0.2317865220308319 1.0 0.5177301422475228 48 P16949,Q08379,O75122,P30622,Q9Y295,O15344,Q92974,P04350,P23258,O00139,Q99996,Q16512,Q9BSJ2,Q9NWH9,P63000 15 +Atp synthesis coupled proton transport 0.5354214818258257 1.195703302401297 0.2318123621892831 1.0 0.5177301422475228 12 P18859,P06576,P56134,O75964,P25705,Q9UJZ1 6 +Positive regulation of low density lipoprotein receptor activity 0.5856262740024692 1.1949349198404178 0.2321124582135909 1.0 0.5182230250776239 3 Q9Y2B0 1 +Prostanoid biosynthetic process 0.5870291379297534 1.193363259929458 0.2327271372716133 1.0 0.5188116807516182 8 Q9H7Z7,P14174 2 +Mitochondrial rna processing 0.5617600809953333 1.1933580798837409 0.2327291651045118 1.0 0.5188116807516182 10 Q969Z0,O15091,Q9Y606,Q8IYB8 4 +Cellular response to fluid shear stress 0.5300089578978866 1.1930315484379483 0.2328570176961952 1.0 0.5188116807516182 2 Q13164 1 +Response to fluid shear stress 0.5300089578978866 1.1930315484379483 0.2328570176961952 1.0 0.5188116807516182 2 Q13164 1 +Positive regulation of hemopoiesis 0.4670456928119779 1.1926656960184532 0.233000325495333 1.0 0.5188116807516182 18 O43290,Q5JVF3,P09429 3 +Negative regulation of protein polymerization 0.4212757090392256 1.1920808577242703 0.2332295420078733 1.0 0.5188116807516182 25 P35241,P16949,P45880,P52907,Q01082,P47755,Q9UEY8,P04350,Q9NYL9,Q13813 10 +Signal peptide processing 0.6406672592351885 1.1918111547565846 0.2333353009360403 1.0 0.5188232279075297 4 Q8TCT9 1 +Uv protection 0.6404909299577146 1.1910487609741451 0.2336344431769346 1.0 0.5189696071132931 4 P18074 1 +Protein containing complex localization 0.3610293208367188 1.190785461738873 0.2337378176470625 1.0 0.5189696071132931 44 Q96D46,Q96GA3,P62841,P15311,O15400,Q8N8E3,Q9H089,Q00839,Q96EE3,P23246,Q99996,Q9UIS9,Q9BTX1,Q12959 14 +Nucleoside triphosphate metabolic process 0.3554616329080891 1.1901415757479965 0.2339907516602997 1.0 0.5191494688561777 47 P18859,P04818,P06576,O60313,Q9H773,O75964,P56134,Q96DE0,P55263,Q9UJZ1 10 +Glial cell differentiation 0.364062559643607 1.189817678183311 0.2341180597688983 1.0 0.5191494688561777 42 P18074,Q00534,P42345,P08670,O14744,P27361,P04062,Q13144 8 +Cellular amino acid biosynthetic process 0.3901685578815348 1.1861803094664192 0.2355511005539117 1.0 0.5210869431236704 32 Q05682,O60568,P00367,P34897,A1L0T0,Q96GX9,Q13126,P00374 8 +Fatty acyl coa metabolic process 0.5192133868613249 1.181723164964856 0.2373155636276147 1.0 0.5237790713635168 13 Q4G176,P53007 2 +Positive regulation of oxidoreductase activity 0.5721575290711551 1.1813070798736771 0.2374807557943996 1.0 0.5237790713635168 9 Q8WTV0 1 +Interleukin 6 production 0.5191351515636264 1.181282824609145 0.2374903880117447 1.0 0.5237790713635168 13 P04062,P09429 2 +Vascular associated smooth muscle cell migration 0.5823312359541373 1.1794107019987736 0.2382346756836173 1.0 0.524534242075333 3 Q96N67 1 +Positive regulation of receptor mediated endocytosis 0.5716098353053454 1.1785848413682856 0.2385635306482825 1.0 0.5250811470525099 9 P50897,Q6P3W7 2 +Pseudouridine synthesis 0.5711584013035421 1.176341189291006 0.2394585625491059 1.0 0.5268734252176215 9 O95900,Q9Y606,Q96HR8,Q9UJK0 4 +Cell migration involved in gastrulation 0.5815318637852109 1.1756458058247217 0.239736443210337 1.0 0.5271293896194945 3 Q4VCS5 1 +Inorganic ion transmembrane transport 0.3197689594197849 1.1743079799410885 0.2402716881250945 1.0 0.5281283383982375 109 P35754,Q93034,O75964,P50570,P21796,Q9UHG3,Q99996,Q99623,Q12959,Q9HD20,P27695,Q96PU5,P06576,Q9UBX3,Q9UDW1,P56134,P17252,Q9UJZ1,Q9UM00,P18859,P46939,P14854,P12235,P16615 24 +Microtubule based process 0.2724478296512287 1.17188681300087 0.2412425021282136 1.0 0.530083693228526 227 Q9UQE7,Q96N67,Q8WUX9,Q96FJ2,Q9UNZ2,Q6UVJ0,Q03001,Q86Y56,O75381,Q16512,Q13409,P04350,Q99996,P57076,Q9NVM9,O95235,P23258,O00139,Q12959,Q9BZD4,Q14254,P15311,P61160,O60313,O95067,P54646,Q14674,Q00839,Q9Y2S7,Q13561,P27695,Q7KZI7,Q9BV86,Q9NWH9,O43663,Q13464,P24941,Q12873,O14530,P12270,O14757,Q8IWJ2,Q92974,P23246,Q5SNT2,Q9BW19,P61758,Q9UIS9,Q9NS87,P16949,Q86UP2,Q08379,O75122,P30622,Q9Y295,O15344,P02545,Q9BSJ2,P53985,P51608,P63000 61 +Regulation of growth 0.3083429183489389 1.1714579789714488 0.2414147389696475 1.0 0.5302836036741566 132 Q6PJG6,Q9P0J0,Q9Y263,Q9ULC4,Q13043,Q09161,Q96PU5,O95067,P50897,Q5BJF2,Q9UBU8,Q9BTE7,Q9BSK2 13 +R loop disassembly 0.6357442326448846 1.1705325087478051 0.2417867396518926 1.0 0.5309220265707442 4 P78362 1 +Response to aldosterone 0.5800644575413039 1.1687359775700632 0.242510021897067 1.0 0.5321740601187742 3 P09874 1 +Regulation of p38mapk cascade 0.6344002319514788 1.1647261260492163 0.2441298700776575 1.0 0.5346280309150312 4 P15311,Q12959 2 +Regulation of early endosome to late endosome transport 0.5158516191006577 1.1628053636049422 0.2449084805147223 1.0 0.5359734218105561 13 P35241,P26038,P15311 3 +Chemical homeostasis 0.2683285868219306 1.1616577429376662 0.2453745168799121 1.0 0.5360944416331794 182 P30519,Q93050,P51572,P04062,Q9Y487,Q8WTV0,O15254,P09601,Q9HD20,P54646,Q5BJF2,Q12846,Q9Y5P4,P27695,Q9NWH9,P12277,Q96PU5,P06576,Q9Y6C9,P42785,Q06481,Q8NE01,P17252,Q9UJZ1,P16949,Q8N511,P09429,P50897,P62753,Q92544,P53985,P16615 32 +Mitochondrion localization 0.4619995602004311 1.1600661028834134 0.2460218938230345 1.0 0.5369288175295714 18 Q6PJG6,O60313,O00429,O75153,P27695 5 +Regulation of stress activated protein kinase signaling cascade 0.3868949664882372 1.1580292138713308 0.2468521147963747 1.0 0.5377025704810218 32 P15311,P36507,P09429,O15344,Q12959 5 +Oxidative rna demethylation 0.5774416434788481 1.156390255820244 0.2475215654688796 1.0 0.5384178579876844 3 Q6NYC1 1 +Oxidative demethylation 0.5774416434788481 1.156390255820244 0.2475215654688796 1.0 0.5384178579876844 3 Q6NYC1 1 +Cell maturation 0.3962449488520392 1.155544502732937 0.2478675194710213 1.0 0.5388352538533929 29 P18074,P04818,P04062,P17252,Q9Y2W6 5 +Synaptic transmission gabaergic 0.632219368839561 1.1553071076671586 0.2479646863546514 1.0 0.5388669807360823 4 P51790,P27695 2 +Inorganic anion transmembrane transport 0.5668044056372354 1.1547087876913418 0.2482096996951805 1.0 0.5392198735721533 9 Q9UHG3 1 +Cardiac muscle cell contraction 0.5005175556598715 1.1535236766138146 0.2486955051833146 1.0 0.5399157906940489 14 Q96PU5,Q99996,Q12959 3 +Positive regulation of stem cell proliferation 0.6317254277710033 1.1531743100628966 0.2488388457464196 1.0 0.540047325354551 4 Q00839,O95251 2 +Telomere maintenance via semi conservative replication 0.6215703577452321 1.1522196912408496 0.2492308080197938 1.0 0.5405384689721418 5 P51530 1 +Neural precursor cell proliferation 0.3907209747979169 1.1511068124286483 0.2496882957214885 1.0 0.5413507700592805 30 P35240,Q8NCG7,Q92974,Q06481,P55209,Q9UBD5,Q9UIS9,O75306 8 +Regulation of gtp binding 0.5944451746823203 1.1490623640294315 0.2505302660077739 1.0 0.5424553802145763 7 P16949,Q86YR5,Q9NWH9 3 +Ires dependent viral translational initiation 0.5267156124398676 1.148211642236524 0.2508812042752195 1.0 0.5430350710116361 12 Q15366,Q9ULC4 2 +Regulation of clathrin dependent endocytosis 0.6300775851292325 1.1460604762020972 0.2517701297972758 1.0 0.5444174509797953 4 Q6P3W7 1 +Growth 0.268268315903081 1.1455962535972302 0.2519622481338148 1.0 0.544512371823436 186 Q09472,O95376,Q15648,P50570,Q14651,Q9BRT9,Q92993,Q6PJG6,Q9P0J0,Q9Y263,Q9ULC4,Q13043,P07602,P16435,P15311,P42345,O95067,P50542,Q5BJF2,Q99816,Q9UBU8,Q5PSV4,Q09161,P25490,Q96PU5,O14757,Q9BTE7,Q9BSK2,P18074,P04818,P29373,P50897,Q9NVI7 33 +Organelle inheritance 0.5646284254754758 1.1439031615295072 0.252663799766446 1.0 0.5456353770696867 9 P36507,P27361,Q08379 3 +Transition metal ion transport 0.5389677346496687 1.1426805803876037 0.2531712355196722 1.0 0.5459998291478457 11 O15173,Q9HD20 2 +Regulation of gastrulation 0.6289214221691202 1.1410706039261589 0.2538405430116826 1.0 0.5467205886779671 4 P63244,O75122,O95747 3 +Protein k48 linked ubiquitination 0.5114831718142745 1.138235914730762 0.2550219856558842 1.0 0.5481195031838013 13 Q8TDB6 1 +Regulation of monooxygenase activity 0.5509427150031141 1.137980642697759 0.2551285653699171 1.0 0.5481195031838013 10 Q8WTV0,P00374 2 +Positive regulation of endothelial cell proliferation 0.5234990506123616 1.1306805337282697 0.2581895774844767 1.0 0.5526222311130518 12 P26583,P09429,P09601,Q9H2J4 4 +Myelin assembly 0.6159593544530952 1.1274763996479642 0.2595411132487841 1.0 0.5549689728248903 5 P18074,Q9Y2J2,Q13614,Q9UPY3 4 +Positive regulation of lamellipodium organization 0.4857737429613855 1.1227643343235487 0.2615375965489148 1.0 0.5581407308954278 15 P61160,Q9BR76,P42345,P50570,P63000 5 +Nucleoside triphosphate catabolic process 0.6136833714488321 1.1174481299540304 0.2638027659477568 1.0 0.5614097048968159 5 Q9H773 1 +Deoxyribonucleoside triphosphate catabolic process 0.6136833714488321 1.1174481299540304 0.2638027659477568 1.0 0.5614097048968159 5 Q9H773 1 +Regulation of carbohydrate catabolic process 0.4848522852800717 1.117280112592797 0.2638745760145768 1.0 0.5614097048968159 15 Q14108,Q09472,P54619 3 +Polarized epithelial cell differentiation 0.5592374332234704 1.1171512465714968 0.2639296620630449 1.0 0.5614097048968159 9 P15311 1 +Positive regulation of lamellipodium assembly 0.520833268673845 1.1161596304364898 0.2643538111633243 1.0 0.5619936859533754 12 P61160,P50570,P42345,P63000 4 +Microtubule cytoskeleton organization 0.271278535018632 1.1145549841804945 0.2650411698914587 1.0 0.562490625922491 177 Q9UQE7,Q96N67,Q8WUX9,Q9UNZ2,Q6UVJ0,Q03001,Q86Y56,O75381,Q8WXH0,Q16512,Q15257,P04350,Q99996,P23258,Q9NVM9,O95235,O00139,Q12959,Q96EA4,Q9BZD4,P15311,O95067,Q13257,P54646,Q14674,O43237,Q00839,Q9Y2S7,Q13561,P29372,Q7KZI7,Q9BV86,Q9NWH9,O43663,Q13464,P24941,Q12873,O14530,Q96FZ7,P12270,O14757,Q8IWJ2,Q92974,P35579,Q9BW19,Q9UIS9,Q9NS87,P16949,Q08379,O75122,P30622,Q9Y295,O15344,Q9UBN7,P02545,Q9BSJ2,P53985,P51608,P63000 59 +Membrane repolarization 0.5584381101384237 1.1131873256311675 0.2656279849216902 1.0 0.5631865593238956 9 Q96PU5 1 +Sphingolipid metabolic process 0.4104098951906082 1.1099418791069222 0.2670240725349504 1.0 0.5650239370400224 25 P07602,P04062,Q96G23 3 +Apoptotic mitochondrial changes 0.3993817029663318 1.107811107610924 0.2679434019888533 1.0 0.5660727230104425 27 P45880,O60313,P12235,O00429,Q96A26 5 +Dendritic transport 0.5849244297129829 1.1047185609528898 0.2692815582037289 1.0 0.5677195156519019 7 Q00839,P23246,Q14254 3 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3900312021732765 1.1046025515401452 0.2693318449982054 1.0 0.5677195156519019 29 O95376,P51572,P04062,P54725,Q8NEZ5,Q96HY6 6 +Positive regulation of long term synaptic potentiation 0.512690355329956 1.103543115627862 0.2697913786312096 1.0 0.5685045324337339 2 Q13501 1 +Steroid metabolic process 0.3234120265683162 1.1024010123869556 0.2702873716054863 1.0 0.5693658447699819 69 Q15648,P37268,P16435,P54646,Q13907,Q15125,Q53GQ0,P04062,Q16850,Q15126,Q15036,Q14534,P38435,Q96SU4,Q8WTV0,Q15800,Q15392 17 +Monocarboxylic acid transport 0.5842636946167792 1.10164464890962 0.2706161893218435 1.0 0.5698745567971445 7 P14174 1 +Hepatocyte growth factor receptor signaling pathway 0.58360771668201 1.098593377288451 0.2719454677185582 1.0 0.5721881565155013 7 P16949,Q9NWH9,P63000 3 +Positive regulation of interleukin 1 beta production 0.6190116819866545 1.0983536014694937 0.2720501145366873 1.0 0.5721881565155013 4 Q14790,P04792 2 +Translational initiation 0.3239376896880105 1.0937330041859632 0.2740720947694868 1.0 0.5743619823494748 67 P46199,Q7Z739,Q9ULC4,P41567,Q09161,Q9NR50,Q9BPZ3,P42345,P12270,P55010,Q13144,P62136,Q9H074,P20042,P46782 15 +Regulation of myoblast differentiation 0.6082790527596884 1.0936580734332917 0.274104968966703 1.0 0.5743619823494748 5 Q15650,Q14254 2 +Pyrimidine deoxyribonucleotide metabolic process 0.5825217871061459 1.093543334436493 0.2741553133647891 1.0 0.5743619823494748 7 P04818,Q9H773 2 +Iron ion homeostasis 0.4365107813779745 1.091786950396214 0.2749267561955082 1.0 0.5754239932430681 20 P09601,P30519 2 +Tetrahydrofolate metabolic process 0.5418516787023961 1.091525503947466 0.2750417158764486 1.0 0.5754800377716268 10 P04818,P00374 2 +Gamma aminobutyric acid metabolic process 0.5100029859659666 1.089697448001007 0.2758464406596963 1.0 0.5762400357699033 2 P51649 1 +Regulation of leukocyte migration 0.3969886915932662 1.0889543902926897 0.2761739992312835 1.0 0.576739686074674 27 P14174,P09429,P09601,Q9UJ41,O00429,P26038 6 +Protein maturation 0.3184071149356159 1.087633577420321 0.2767569014209534 1.0 0.5776587959201086 74 Q09472,P41227,P67812,P50579,Q9BXJ9,Q9BU89,Q8TCT9,O76071,Q86UY6,P42892,Q96TA2,P17252,Q9UBS4,Q10713,Q15392 15 +Skin development 0.3547813132755225 1.085781292796697 0.2775757647842236 1.0 0.5782452045926785 41 P04062,Q13043,Q15392 3 +Mrna modification 0.4888316059366468 1.0857209405147674 0.2776024732253406 1.0 0.5782452045926785 14 O95900,Q9Y606,Q96FX7 3 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3547405450474512 1.0853849664913526 0.277751187952278 1.0 0.5783676619580621 41 P46379,O95376,P62195,P62191,Q9NZM5,Q8IXJ6,P53350,P51572,Q6ZXV5,P04062,O60826,Q96JB5,P54725,Q9Y4X5,Q8NEZ5,Q9Y5A7,Q96HY6 17 +Binding of sperm to zona pellucida 0.5273529090829225 1.0814590998208131 0.2794929447237226 1.0 0.5812526951137712 11 P45880 1 +Sperm egg recognition 0.5273529090829225 1.0814590998208131 0.2794929447237226 1.0 0.5812526951137712 11 P45880 1 +Nucleoside phosphate catabolic process 0.4497561721291575 1.081067078528483 0.2796672764348082 1.0 0.5812607791187296 18 Q9BQG2,Q9NRG1,Q96DE0,Q9H773 4 +Negative regulation of supramolecular fiber organization 0.3337145861127434 1.0808596579473002 0.2797595461773245 1.0 0.5812607791187296 53 P04350,P52907,Q13177,Q13485,P47755,Q9NWH9,P29372,Q01082,Q9NQP4,Q92974,Q99471,Q9NYL9,P61758,P35241,P16949,O75122,Q9BR76,O94813,O15344,Q9UBN7,Q9UEY8,P60983,Q13813 23 +Positive regulation of oligodendrocyte differentiation 0.6144770083014108 1.0788427225396988 0.2806578460014208 1.0 0.5827170796097053 4 P42345 1 +Cell cycle dna replication initiation 0.5949177877429074 1.0777652797602602 0.2811385177546448 1.0 0.5831881649290566 6 Q9BRX5,P09884,P33991,P49736,P25205 5 +Positive regulation of non motile cilium assembly 0.613786769927865 1.0758751836983709 0.2819830819072297 1.0 0.5841973309608195 4 P27695 1 +Negative regulation of epidermal growth factor activated receptor activity 0.6038135173119629 1.074026862956346 0.2828106419112717 1.0 0.5855400536525885 5 Q99816,Q9UNH7 2 +Regulation of epidermal growth factor activated receptor activity 0.6038135173119629 1.074026862956346 0.2828106419112717 1.0 0.5855400536525885 5 Q99816,Q9UNH7 2 +Myeloid cell activation involved in immune response 0.5254310734715989 1.0713466662209696 0.2840135841789366 1.0 0.5869956869018694 11 Q9UJ41,P09601,Q9UNH7 3 +Cellular response to ether 0.5064198268139813 1.071258123965605 0.2840533832724645 1.0 0.5869956869018694 2 Q6PKG0 1 +Negative regulation of rho protein signal transduction 0.5934088249928657 1.0709859281253826 0.28417575694564 1.0 0.5870626748424332 6 P16949,Q9H3F6 2 +Nitrogen compound transport 0.2595178327463946 1.0698408666791186 0.2846909438799567 1.0 0.5873073012966985 570 O60830,P24390,P67809,Q99595,O43615,Q9H2D1,Q32P28,P09132,Q9Y5J9,Q8WUX9,P55735,O75381,Q9NS69,P33908,Q14108,P08183,Q9Y282,Q9P0J0,Q13043,P07602,P15311,Q9HD20,Q16850,Q96PU8,O95070,P27695,Q10713,O15173,O75695,Q96KC8,P00367,Q09161,Q8TDB6,O00429,Q5JVF3,Q06481,Q9BSK2,Q9P2W9,Q6P4A7,O60725,P05455,Q9Y5L4,Q9UNH7,Q8TCT9,P51159,P50897,P12235,Q92544,Q9Y3B3,Q96EE3,P61960,P53985,Q8IUD2,Q9BTX1 54 +Presynaptic modulation of chemical synaptic transmission 0.5061212302179829 1.069722697288432 0.2847441466905844 1.0 0.5873073012966985 2 P35268 1 +Transition metal ion homeostasis 0.3977492794511811 1.0636159641246974 0.2875027074802032 1.0 0.5907565078765133 26 P09601,P30519 2 +Negative regulation of release of cytochrome c from mitochondria 0.6104935777090208 1.0617256646513529 0.2883602447005344 1.0 0.5912155064139767 4 P02545,O60313 2 +Export from cell 0.3021292646560485 1.0602187255843512 0.2890451040064468 1.0 0.5922475192295359 131 P35580,Q32P28,Q13555,Q16512,P08183,Q7Z392,Q15019,Q12959,O14795,P15311,P09601,Q16850,Q12846,P27695,Q4J6C6,P14174,Q96KC8,P00367,O00429,Q9UPT5,O43760,O75122,Q9UNH7,P51159,P50897,Q9UJ41,P53985,P16615 28 +Male gamete generation 0.310250271650328 1.0590338857881791 0.2895843476793258 1.0 0.592980060544487 80 Q14997,Q9BY67,Q9BPZ3,P51572,P50570,P54619,Q15019,P26583,Q14141,Q96PU8,Q9Y2W6,P25490,O75718,P16104,P17252,Q9UHB7,Q9P0K7,Q9Y4C1,Q9BTX1 19 +Neuron death 0.3113025710468197 1.0584471204345418 0.2898516466906184 1.0 0.5930163446759626 79 Q96A26,Q9NR28,P78362,Q9UNH7,Q15233,P09601,P50897,P04062,Q15392 9 +Attachment of mitotic spindle microtubules to kinetochore 0.6002615125707313 1.0584307746577768 0.2898590953324156 1.0 0.5930163446759626 5 Q9BZD4,Q96EE3 2 +Peptidyl lysine hydroxylation 0.5749547186176075 1.0583965830321151 0.2898746766037881 1.0 0.5930163446759626 7 Q6NYC1,O60568 2 +Cellular response to epinephrine stimulus 0.5558519605709054 1.0550823848195556 0.2913876475928949 1.0 0.5950097387771573 3 P17252 1 +Response to epinephrine 0.5558519605709054 1.0550823848195556 0.2913876475928949 1.0 0.5950097387771573 3 P17252 1 +Ventricular cardiac muscle cell membrane repolarization 0.55582970073628 1.0549782999719777 0.2914352493914045 1.0 0.5950097387771573 3 Q99996 1 +Plasma lipoprotein particle clearance 0.5346619207652428 1.054864495503898 0.2914873023093123 1.0 0.5950097387771573 10 Q8WTV0 1 +Negative regulation of ion transport 0.4257945628189264 1.0529926294607863 0.2923443701296888 1.0 0.5953327462799121 21 Q96PU5,P21796 2 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.5990065947651173 1.0529250649304736 0.2923753373930613 1.0 0.5953327462799121 5 Q15648,Q16512 2 +Golgi disassembly 0.6083490976718493 1.0525199894694222 0.2925610443000104 1.0 0.5955007229790447 4 Q08379 1 +Icosanoid metabolic process 0.4346098650830822 1.047440843241541 0.2948963025911908 1.0 0.596346779666242 19 P14174,Q9H7Z7,P07099,Q8NCG7 4 +Tail anchored membrane protein insertion into er membrane 0.5331889162452746 1.0473639605705611 0.294931746919818 1.0 0.596346779666242 10 Q9P0I2,Q7L5D6,O43681,Q15006 4 +Regulation of translational initiation 0.353739333046849 1.0472699638732352 0.2949750850080646 1.0 0.596346779666242 40 P46199,Q7Z739,P41567,Q09161,P42345,Q9BPZ3,P12270,P55010,Q13144,P62136,Q9H074 11 +Positive regulation of translational initiation 0.5328846667481635 1.0458152049745797 0.2956463596970322 1.0 0.5971489146960175 10 Q7Z739,P42345,Q13144 3 +Long chain fatty acyl coa metabolic process 0.5556562714368636 1.042255655993329 0.297293165526856 1.0 0.5999181194274157 8 Q4G176 1 +Positive regulation of autophagy of mitochondrion 0.5869361421558901 1.041943317640753 0.2974379592370439 1.0 0.6000247672274958 6 P21796 1 +Protein dna complex disassembly 0.4809999952837103 1.0403962036154384 0.2981558647592712 1.0 0.6009483238933595 14 Q9BQ67,Q969G3,P17096 3 +Cytokine production involved in inflammatory response 0.5705595113851836 1.03802148976956 0.2992600504114273 1.0 0.6022112516142383 7 Q06481 1 +Positive regulation of lipid localization 0.5312629532505352 1.0375628901638738 0.2994736023006201 1.0 0.6024552184383006 10 Q8WTV0 1 +Response to toxic substance 0.3438934920536896 1.034617755154128 0.300847458809653 1.0 0.6038354295870995 45 P07099,P08183,P00374,Q15165 4 +Cellular senescence 0.4178974131640542 1.0345754911472005 0.3008672047789604 1.0 0.6038354295870995 22 P67809,Q00534,P24941,O60313,Q92993,P17096 6 +Protein localization to cell cortex 0.5692633328025549 1.032018903213414 0.3020632621793946 1.0 0.6050026566436908 7 P15311,Q14980,P53350 3 +B cell apoptotic process 0.5942035602335847 1.0318753768283375 0.3021305022987723 1.0 0.6050026566436908 5 P14174 1 +Regulation of cell cycle g1 s phase transition 0.3520537996205951 1.0311579259133148 0.3024667674138726 1.0 0.6054128298383502 40 P35241,P24941,P15927,Q6UVJ0,P61289,Q06481,Q99623,P27695,Q96HY6,Q12959 10 +Regulation of innate immune response 0.3306085424094154 1.0308613018189077 0.3026058661339466 1.0 0.6054128298383502 52 Q09472,Q7Z739,Q15648,Q15233,Q9BY67,P26583,P09429,Q3LXA3,Q8WXF1,Q06481,Q14166,Q9NUD5 12 +Regulation of excretion 0.5496224857583059 1.025991141267179 0.3048957597527404 1.0 0.6077427392017055 3 Q9Y5X3 1 +Cellular response to molecule of bacterial origin 0.3664341763270169 1.0252774601503516 0.305232287982057 1.0 0.608042097488066 34 P14174,Q9Y263,P26583,P08670,P09429,Q8WTV0 6 +Neurotransmitter metabolic process 0.6017349165395527 1.024172198536248 0.3057539477045705 1.0 0.6085240203476753 4 Q8NCG7 1 +Regulation of signal transduction by p53 class mediator 0.3590468807100599 1.0237298048756065 0.3059629135754571 1.0 0.6087542603638516 37 Q09472,P14174,Q9NYV6,P62841,P42345,O14757,Q9NZM5,P61254,P62081,O14744,Q96JB5 11 +Negative regulation of blood pressure 0.6014593386980398 1.0229926736679864 0.3063113098114001 1.0 0.6090942723731303 4 P42785 1 +Response to amyloid beta 0.6012516412804043 1.0221037773175214 0.3067317855788003 1.0 0.6090942723731303 4 Q9UNH7 1 +Cellular response to amyloid beta 0.6012516412804043 1.0221037773175214 0.3067317855788003 1.0 0.6090942723731303 4 Q9UNH7 1 +Semaphorin plexin signaling pathway 0.5513155419218053 1.021454018926171 0.3070393834072598 1.0 0.6092243892112428 8 O94887,P42892,P63000 3 +Lipid localization 0.3154453329282692 1.0201623314292687 0.3076514791818194 1.0 0.6102533596171896 71 P07602,Q00169,P04062,Q14108,P08183,Q8WTV0 6 +Positive regulation of synaptic transmission 0.4592535742485901 1.0199068765054038 0.30777262795511 1.0 0.6103081647022329 16 P33176,O75955,Q9BPZ3,Q12846,P51608,P27695 6 +Negative regulation of organ growth 0.5913774684679048 1.019507781083525 0.3079619610120632 1.0 0.6104981037559916 5 Q13043 1 +Cell aging 0.3706071224363759 1.0182917346263027 0.3085393351976335 1.0 0.6109273560204784 32 P67809,P14174,Q00534,P24941,O60313,O14757,P16104,P02545,Q96EY1,Q92993,P17096 11 +Negative regulation of mrna 3 end processing 0.5662791385437718 1.0182106086869886 0.3085778789367208 1.0 0.6109273560204784 7 P18615 1 +Positive regulation of signal transduction by p53 class mediator 0.5152847138556931 1.0180660534154793 0.3086465664724973 1.0 0.6109273560204784 11 Q96JB5,P62841,P62081 3 +Cd4 positive alpha beta t cell differentiation 0.5814369972836099 1.0173220716592593 0.3090002401096821 1.0 0.6114419548076971 6 P09429 1 +Response to thyroid hormone 0.5499895306909941 1.0151066276895635 0.3100550026623097 1.0 0.6130095627470644 8 P35241,P04062 2 +Negative regulation of cell size 0.5992799154027941 1.0136690640030137 0.3107406904295564 1.0 0.6137692935058369 4 P35241 1 +Circadian regulation of gene expression 0.4246754237969149 1.0118543264777344 0.3116077100850996 1.0 0.6152955872966293 20 Q9BQG2,O14744,P43490,Q00839 4 +Protein localization to endosome 0.4757580907216124 1.0101300944250091 0.3124329656127069 1.0 0.6165520210427958 14 P35241,P26038,Q8TDB6,P15311 4 +Trna 5 leader removal 0.5887657413542889 1.0080910391925295 0.3134107590522679 1.0 0.617374318937333 5 P05455 1 +Ribonucleoprotein complex disassembly 0.588544779233946 1.0071257233884554 0.3138743611465249 1.0 0.617374318937333 5 P33176,Q9UBB9 2 +Receptor signaling pathway via stat 0.4570876669644504 1.006745814856404 0.3140569394871269 1.0 0.617374318937333 16 Q13043,P35240 2 +Sphingomyelin biosynthetic process 0.5975778694957993 1.006393690152243 0.3142262277061189 1.0 0.617374318937333 4 O15269,Q9P0L0 2 +Unsaturated fatty acid biosynthetic process 0.5249652758141783 1.005565881402429 0.3146244431329212 1.0 0.6175155235745697 10 Q9H7Z7,P14174 2 +Actin filament based movement 0.3821731175524067 1.0047020957434754 0.3150403187167923 1.0 0.6177540413241491 28 Q9Y4I1,P35580,Q13464,A0MZ66,Q96PU5,O43707,O94832,Q8WXH0,P35579,Q99996,P16615,Q12959 12 +Negative regulation of programmed necrotic cell death 0.5879498473396523 1.0045271120633976 0.3151246098020368 1.0 0.6177540413241491 5 Q92974,P12235 2 +Negative regulation of necrotic cell death 0.5879498473396523 1.0045271120633976 0.3151246098020368 1.0 0.6177540413241491 5 Q92974,P12235 2 +Regulation of glucocorticoid metabolic process 0.4932815765900327 1.003899324296189 0.3154271423029562 1.0 0.618020128861454 2 P05023 1 +Mitochondrion morphogenesis 0.5362822872491525 1.003686229102811 0.3155298767691379 1.0 0.618020128861454 9 O00429,Q9Y5P4,Q9Y2S7,Q04837 4 +Endocrine process 0.5969370701935677 1.003656008123086 0.3155444482633105 1.0 0.618020128861454 4 P42892 1 +Mitotic cell cycle phase transition 0.2918509299835794 1.0014171090684536 0.3166251959718709 1.0 0.6191982705432975 140 Q96BK5,Q9UJX5,Q93034,Q9NZM5,Q8WUX9,Q6UVJ0,P49959,P50570,Q7Z7L1,Q99623,P08183,Q12959,Q96EA4,Q00534,P15927,O95067,P61254,Q6NUQ1,Q14674,Q16763,Q9UJX4,Q9H1A4,Q96JB5,P27695,P24941,P12270,O14757,O95905,Q5JVF3,P19447,Q06481,P61289,Q9UJX2,Q68E01,P35241,P18074,Q92547,O75122,P54132,P62753,Q01664,P51608,O60885 43 +Leukocyte degranulation 0.4868903160838049 1.0004185536916832 0.3171079947730313 1.0 0.6195948424816773 13 Q9UJ41,P09601,P51159,Q9UNH7 4 +Regulation of ph 0.4127754763803116 0.9985872536841134 0.3179946772997786 1.0 0.6205841100652976 22 Q96AX1,Q8N511,P06576,Q93050,P50897,P27361,Q92544,Q9Y487 8 +Regulation of cellular ph 0.4127754763803116 0.9985872536841134 0.3179946772997786 1.0 0.6205841100652976 22 Q96AX1,Q8N511,P06576,Q93050,P50897,P27361,Q92544,Q9Y487 8 +Cell projection organization 0.2608028331114736 0.9971371477265804 0.3186979439112449 1.0 0.6212341209379654 265 Q09472,Q32P28,Q96FJ2,P50570,P04062,Q14651,Q9UQB8,P35613,Q14108,P57076,Q15019,P00374,Q9Y263,P15311,Q9Y5K8,Q14141,P27695,Q66K14,Q7KZI7,O75695,Q96PU5,P08670,Q99873,Q9HCE1,P51116,Q06481,Q4KMP7,P35241,P16949,Q96G23,Q9BR76,O00264,P09429,Q9UNF0,P63000,Q01968 36 +Peptidyl arginine methylation 0.5859347486476941 0.9957304572356688 0.3193811274448312 1.0 0.6219958839974998 5 O14744,Q99873 2 +Peptidyl arginine n methylation 0.5859347486476941 0.9957304572356688 0.3193811274448312 1.0 0.6219958839974998 5 O14744,Q99873 2 +Myeloid leukocyte cytokine production 0.5229470448986551 0.9953299483645884 0.3195758166312696 1.0 0.6221813184175613 10 P09601 1 +Histone threonine phosphorylation 0.5852876156733104 0.9929071961615769 0.3207551825588695 1.0 0.6239190227657772 5 P17252,O14757,Q16512 3 +Lymphocyte activation 0.3077259957574412 0.990263524428661 0.3220453301685064 1.0 0.6257294293229112 106 Q09472,P24390,Q9BY67,P04062,Q16512,Q96FZ2,Q99623,Q12959,Q00534,Q14254,P13051,P14174,P25490,O43290,Q5JVF3,Q9UJZ1,O96005,P09429,P51159,P62753,Q6NYC1,P26038 22 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5602171313679257 0.9902141901526216 0.3220694381084368 1.0 0.6257294293229112 7 Q9NUD5,Q8TAT6,Q3LXA3 3 +Myeloid leukocyte migration 0.4000922059471789 0.9871847596819388 0.3235520716868205 1.0 0.6276756301510675 24 P14174,P09429,P35613 3 +Stress granule disassembly 0.5412038455421702 0.9868091311054032 0.323736217515135 1.0 0.6278462274899765 3 P33176 1 +Mast cell activation involved in immune response 0.5593100165393127 0.9860314431940392 0.3241176834128461 1.0 0.6280261288456751 7 P09601,Q9UNH7 2 +Regulation of secretion 0.3075948057548475 0.9851802094664864 0.3245355599258244 1.0 0.6283264588925623 92 P14174,Q96KC8,P00367,Q9UNH7,P15311,Q32P28,P09601,P51159,Q16850,O00429,P53985,P27695,Q15019 13 +Cellular response to insulin stimulus 0.3219808674504422 0.984157823942052 0.3250379194439394 1.0 0.6289399577947761 55 P43490,Q9UQB8 2 +Positive regulation of neuron projection development 0.3751947234438597 0.983368884681771 0.3254259184634525 1.0 0.6289399577947761 29 Q32P28,Q9UQB8 2 +Positive regulation of protein dephosphorylation 0.4706688923661603 0.9808120579228052 0.3266854309530971 1.0 0.6306073745841544 14 P04062 1 +Cellular macromolecule localization 0.257350992416532 0.9807703005676444 0.3267060271941504 1.0 0.6306073745841544 557 O60830,Q16181,P24390,Q99595,O95376,Q15648,P09132,P49257,P83436,Q6GQQ9,Q7L5D6,Q9NS69,P35613,Q14108,Q96CS3,Q99623,Q9NVM9,Q9Y282,P49354,Q9P0J0,Q13043,Q9HD45,Q13561,Q8TDB6,Q96PU5,O60725,Q9Y5L4,Q8TCT9,O00264,Q92544,P61960,P67809,O43615,Q15006,Q9Y5J9,Q8WUX9,Q14789,P55735,O75381,P33908,Q15019,Q12959,P15311,Q9Y5K8,Q9HD20,Q14141,P27695,Q10713,Q9Y6C9,O00429,Q06481,Q9P2W9,P35241,P05455,Q9UNH7,Q96EZ8,P51159,O15344,Q9Y3B3,P31483,P26038,Q96BK5,P35240,Q14651,Q96HY6,Q8N4H5,P50542,P15927,Q4J6C6,O43681,O14737,Q8IWJ2,Q9UPT5,Q9Y2L5,P17252,Q9NPI6,Q9BR76,Q9P0I2,Q9UJ41,Q9UNF0,Q15036,P51572,P40855,Q9H267,Q14254,Q00839,Q12846,Q8TAT6,Q96JB5,P12270,P49458,Q9UIS9,Q9Y4I1,O75122,Q86TV6,Q5JTV8,Q96A33,Q9C0E2,Q8N1F7 99 +Cardiolipin metabolic process 0.5580605023310996 0.9802728677494824 0.3269514439640808 1.0 0.6308195135891901 7 Q99623,Q6UWP7,Q9UJZ1 3 +Intracellular estrogen receptor signaling pathway 0.3989551512305858 0.9788496469020156 0.3276542748484266 1.0 0.6313505148335908 24 Q15648,O94874,Q15650,Q16512,P61960,Q99623,Q96HY6,Q9NUQ7 8 +Negative regulation of cell killing 0.4882054344580545 0.9780011387218616 0.3280737608880637 1.0 0.6315661839396767 2 P04439 1 +Regulation of membrane repolarization 0.5725002555677081 0.977431569201918 0.3283555403907401 1.0 0.6317789852487404 6 Q96PU5 1 +Vitamin metabolic process 0.3744599102065549 0.9773863424761782 0.3283779218454992 1.0 0.6317789852487404 29 Q9H2D1,P04062 2 +Endothelial cell migration 0.3538213716248833 0.9759212938716576 0.3291034689527823 1.0 0.631798372694459 37 P19174,P06576,Q9BR76,P09429,Q8WTV0,P09601,P42785,P25705,P35579,P17252,P51608,Q9NWH9,P67870,P63000,Q4VCS5 15 +Metencephalon development 0.3922037282126663 0.9728464106162528 0.3306296424438586 1.0 0.63312472024314 25 P48444,P12277,Q14103,P04062,P51608,P27695 6 +Voluntary musculoskeletal movement 0.5894857430456407 0.9718819435577928 0.3311092836209184 1.0 0.6335229795114308 4 P42345,P18887 2 +Positive regulation of protein localization to cell periphery 0.4231669107098063 0.971842616019486 0.3311288512279329 1.0 0.6335229795114308 19 P15311,Q14651,O00264,Q12959 4 +Positive regulation of interleukin 1 production 0.5561154730892004 0.971315999882263 0.3313909436930142 1.0 0.6336528855964286 7 P49755,P04792,P09429,Q14790 4 +Sodium ion export across plasma membrane 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.6341121515970001 3 P54709,P05023 2 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.5058958981634873 0.9689634692662896 0.3325634161006299 1.0 0.6346024748051005 11 P26583,Q12846,P09601,Q13043 4 +Regulation of microtubule polymerization or depolymerization 0.3526968519199554 0.9656543278946568 0.3342171804557794 1.0 0.6358895975668852 37 P16949,O75122,P30622,Q9Y295,O15344,Q92974,Q16512,P04350,P63000,Q99996,Q9NWH9 11 +Autophagy of mitochondrion 0.3591873389624523 0.9616319154659192 0.3362345337371617 1.0 0.6382879878775906 34 O00429,P04062,P21796,P12235 4 +Polyol metabolic process 0.3845056182305286 0.9615721796633088 0.3362645518496103 1.0 0.6382879878775906 26 P04062,P00374,Q3LXA3 3 +Icosanoid biosynthetic process 0.5032708630708297 0.9552763780196376 0.3394379499484583 1.0 0.6425027115583111 11 Q9H7Z7,P14174 2 +Interleukin 6 mediated signaling pathway 0.5849705490763358 0.9526865016575962 0.3407489345594714 1.0 0.6439987103779642 4 Q13485,Q6PD62 2 +Cellular pigmentation 0.5025042926658487 0.9512832245652996 0.3414606204224175 1.0 0.6449701907023724 11 Q9Y4I1,Q9H267,Q13561,P51159 4 +Regulation of ubiquitin protein ligase activity 0.4779233687020484 0.9505025100359576 0.3418569791131642 1.0 0.6455320155360271 13 P62841,Q13257,P62081,O00429,Q16763,P46777,P62913 7 +Muscle contraction 0.3263906696400686 0.9481078194950074 0.3430745678866373 1.0 0.6471595208810075 50 Q05682,Q86U42,Q86TU7,P46939,P06753,Q96PU5,P17252,P16615,Q9Y4J8,Q99996,Q9Y5P4,P67936,Q12959 13 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.583827022206388 0.9478325728827895 0.3432146953369854 1.0 0.6471595208810075 4 Q3LXA3 1 +Actin mediated cell contraction 0.4288613217068504 0.946940854929006 0.3436689180969345 1.0 0.6476417440082574 18 Q96PU5,Q99996,Q12959 3 +Regulation of leukocyte degranulation 0.5355357322208292 0.9461721152255372 0.3440608062519503 1.0 0.6480060091198349 8 Q9UJ41,P09601 2 +Hormone mediated signaling pathway 0.325962872738917 0.943559679531712 0.3453947047244594 1.0 0.6495809345913033 50 O15173,Q09472,Q9NS86,Q15648,O94874,Q15650,P42785,Q06481,Q16512,P61960,Q99623,Q9Y4C1,Q96HY6,Q9NUQ7 14 +Regulation of lamellipodium organization 0.4371844794803708 0.9410143884119472 0.3466974857399969 1.0 0.6512803085605123 17 P61160,Q9BR76,P42345,P50570,P63000 5 +Regulation of erythrocyte differentiation 0.4550047692856949 0.9405280299581452 0.3469467788427036 1.0 0.6513644588226933 15 Q00534,Q15648,P26583,O95251,Q99873 5 +Cellular response to virus 0.4092997169871114 0.9396868033229908 0.3473782362396211 1.0 0.6513644588226933 21 O15111,Q9H078,Q3LXA3,Q9NUD5,Q8TAT6,Q99623 6 +Macromolecule deacylation 0.3344546819438653 0.9395645712154918 0.3474409563533245 1.0 0.6513644588226933 45 P49354,Q9UBU8,Q9NUJ1 3 +Regulation of myotube differentiation 0.5726607332974556 0.9380038625715844 0.3482424251085221 1.0 0.6526795135721468 5 Q8NEZ5 1 +Steroid biosynthetic process 0.3253539850276469 0.9370893960921606 0.348712575494962 1.0 0.6533469403620781 50 Q15648,P37268,P16435,P54646,Q13907,Q15125,Q53GQ0,Q16850,Q15126,Q14534,Q96SU4,Q15800,Q15392 13 +Regulation of protein secretion 0.3446767352396234 0.9360717458832942 0.3492362490957204 1.0 0.6533469403620781 39 Q96KC8,P00367,P15311,Q32P28,Q16850,P53985 6 +Cellular response to nutrient 0.5483973643447759 0.9358657475448208 0.3493423147203489 1.0 0.6533469403620781 7 P09601 1 +Unsaturated fatty acid metabolic process 0.4037000930731196 0.9350480411292628 0.3497635418591514 1.0 0.6533469403620781 22 P14174,Q9H7Z7,P07099,Q8NCG7 4 +Membrane invagination 0.4751252743581148 0.9349774717638468 0.3497999095349526 1.0 0.6533469403620781 13 Q14185,P51790,Q4KMQ2,Q06481,P63000 5 +Regeneration 0.3583534563956153 0.9330054990178532 0.3508171291267272 1.0 0.6546816841705652 33 Q96G23,P09601,P00374,P62841 4 +Inositol lipid mediated signaling 0.4358626678540647 0.932814403505962 0.3509158031303458 1.0 0.6546816841705652 17 P42356,Q969H8,P49815,P15311,Q9NZM5,Q9UBF8,O95630,Q10713 8 +Platelet morphogenesis 0.5475218817423544 0.931854444610622 0.3514117532564123 1.0 0.6548183846534501 7 Q96AX1,Q09472,P12814 3 +Branching morphogenesis of an epithelial tube 0.4264902960036198 0.9318083674058728 0.3514355696015738 1.0 0.6548183846534501 18 Q15648,Q13043,Q13485,Q14344,Q9UNS1,P62136,Q16512,Q99623,Q9NWH9,Q12959 10 +Transcription elongation from rna polymerase i promoter 0.5798763295417355 0.9310878642444268 0.3518081156505286 1.0 0.6550355956448929 4 P18074 1 +Positive regulation of blood vessel endothelial cell migration 0.4741008797090809 0.929300425769178 0.3527334146336205 1.0 0.6562083383717098 13 P06576,P09429,P09601,P25705,P17252 5 +Cellular response to peptide 0.3051479136977812 0.928650747927466 0.3530701129872251 1.0 0.6564488767392112 75 P43490,P08670,Q9UQB8,Q9BSK2,Q06481,P27695 6 +Positive regulation of fatty acid biosynthetic process 0.4774559570020996 0.9234462033181624 0.3557747232029806 1.0 0.6597856901457219 2 P04083 1 +Phosphatidylglycerol acyl chain remodeling 0.4774559570020912 0.92344620331812 0.3557747232030026 1.0 0.6597856901457219 2 Q8NF37 1 +Positive regulation of actin nucleation 0.5776972137181229 0.921868989166848 0.3565969164707674 1.0 0.660934813089528 4 P14373 1 +Cellular response to biotic stimulus 0.3350278544583218 0.9175134685979296 0.3588736384591025 1.0 0.663664024317185 43 Q86U42,P14174,Q9Y263,P26583,P08670,P09429,P17252,Q8WTV0,Q9UM00 9 +Neuron projection guidance 0.3786036396462105 0.916339956783372 0.3594886170299385 1.0 0.664031337315986 26 O00264,P63000,P35613 3 +Positive regulation of ubiquitin protein transferase activity 0.5183787150528362 0.9159669280901676 0.359684241220493 1.0 0.6640910964643066 9 Q9BTE7,Q96GG9,P15880 3 +One carbon metabolic process 0.4716783462604882 0.9158901937122276 0.3597244906529764 1.0 0.6640910964643066 13 P04818,P00374 2 +Regulation of ubiquitin protein transferase activity 0.3901938809052941 0.9148162632796216 0.3602880954954155 1.0 0.6647692852923274 24 Q8TDB6,O00429,Q9BTE7,P62841 4 +Microtubule based movement 0.303223803908307 0.914802006859507 0.3602955810724735 1.0 0.6647692852923274 76 Q03001,Q86Y56,Q8WXH0,O75381,Q13409,Q9UBF2,O00139,P57076,Q9NVM9,O95235,Q14254,P61160,O60313,Q00839,O43237,P27695,P33176,Q99661,P23246,Q5SNT2,Q9BW19,Q9UIS9,Q9NS87,Q9Y496,Q86UP2,O60333,Q9UBN7 27 +Spermatid differentiation 0.4052556960568826 0.9120662140093396 0.3617338624930015 1.0 0.6668573973529176 21 Q14997,P26583,Q96PU8,P17252,Q9UHB7 5 +Ovarian follicle development 0.5573025599154457 0.910018022406724 0.3628130052752476 1.0 0.6684566627172723 6 P35221,Q13144 2 +Positive regulation of attachment of spindle microtubules to kinetochore 0.5748485003194794 0.9098366439530836 0.3629086662591627 1.0 0.6684566627172723 4 Q00839,Q8IXJ6 2 +Regulation of oxidoreductase activity 0.4317074947812419 0.9070837792779308 0.3643624951400883 1.0 0.6694340211948808 17 Q8WTV0,P00374 2 +Negative regulation of calcium ion transport 0.5049563999166462 0.9045701477045572 0.3656931562657215 1.0 0.6709433861806903 10 P21796 1 +Locomotor rhythm 0.5735977449265195 0.9045608704749608 0.365698073037805 1.0 0.6709433861806903 4 P42345 1 +Monocyte differentiation 0.541188431311794 0.902901615120771 0.3665781133763008 1.0 0.6716139157478214 7 O00625,Q00534,Q15648 3 +Nephric duct development 0.473275604658111 0.9023512531669554 0.3668703072593082 1.0 0.6717720609355347 2 O95747 1 +Nephric duct morphogenesis 0.473275604658111 0.9023512531669554 0.3668703072593082 1.0 0.6717720609355347 2 O95747 1 +Cation transport 0.2820692057031694 0.9016178610300808 0.3672598996757781 1.0 0.6722968037262631 148 Q70HW3,P35754,Q93034,Q13555,O75964,P50570,P21796,Q99996,Q99623,Q12959,Q9HD20,Q9HC21,P27695,O15173,P24941,Q96PU5,P06576,Q9UKS6,Q9UDW1,P56134,O00429,P17252,Q9UJZ1,Q9UM00,P18859,P46939,Q9UNH7,P14854,P12235,P16615 30 +Regulated exocytosis 0.349661156043705 0.9008264593232144 0.3676805970029022 1.0 0.6728781761191643 35 O43760,Q9UNH7,P51159,P09601,Q9UJ41,P16615,Q4J6C6 7 +Retrograde axonal transport 0.5149480435683118 0.8992655855218801 0.3685112135719846 1.0 0.6738970441720082 9 Q03001 1 +Response to estrogen 0.4479440939322906 0.8991028276439632 0.3685978921016206 1.0 0.6738970441720082 15 P04062 1 +Regulation of t cell mediated immunity 0.5403338477710147 0.8990042622147254 0.3686503903913682 1.0 0.6738970441720082 7 P09429 1 +Endothelial cell proliferation 0.421239839921383 0.8983831937383074 0.3689812932254801 1.0 0.6743130550516616 18 P26583,P09429,P09601,Q9H2J4,Q8WTV0,Q12959 6 +Negative regulation of immune system process 0.3286638503414314 0.8967971644742285 0.3698271613072195 1.0 0.6751026726408152 46 Q7Z739,P14174,Q00534,P09429,P09601,Q12959 6 +Regulation of lamellipodium assembly 0.455769346433674 0.895457489992045 0.3705425803744471 1.0 0.6758414979104644 14 P61160,P42345,Q9Y2A7,P50570,P63000 5 +Positive regulation of dephosphorylation 0.446976890099059 0.8934442219100894 0.3716193298521224 1.0 0.6770485054759774 15 P04062 1 +Regulation of endothelial cell migration 0.3596150174009273 0.8921885291219147 0.3722918895082507 1.0 0.6777062401480737 30 P19174,P06576,P09429,Q8WTV0,P09601,P42785,P25705,P63000,P17252,P51608,Q9NWH9,P67870 12 +Interleukin 1 production 0.5131039347367365 0.8903045865956202 0.3733023590068747 1.0 0.6785994353895242 9 P49755,P04792,P09429,Q14790 4 +Regulation of multicellular organism growth 0.4548434882017791 0.8901816676379009 0.3733683466495576 1.0 0.6785994353895242 14 P15311,Q14651 2 +Cellular response to cold 0.5201880688482156 0.8898469108227395 0.3735480936433699 1.0 0.6786678338297975 3 P17252 1 +Digestion 0.4668682486780713 0.8893303118013488 0.3738255855264731 1.0 0.6789829588493637 13 P15311,O00625,Q8WTV0 3 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.466657937851205 0.8881711886011276 0.3744486741889383 1.0 0.6799213087068664 13 P67809,O60506,Q14103,Q00839,Q9H074 5 +Protein demethylation 0.5121325407017367 0.8855891765893434 0.3758389460388023 1.0 0.6803822990087921 9 Q8IUF8,Q6NYC1 2 +Amide biosynthetic process 0.250376544263716 0.8853517390774331 0.3759669529379565 1.0 0.6803822990087921 388 Q7Z739,P67809,Q8N5C6,Q9Y285,O15269,P62841,P34897,P23381,Q9BPZ3,Q96EY7,Q567V2,P04062,O75879,P00374,P46199,Q9BTE6,Q9HA77,Q15024,Q9ULC4,Q14103,P42345,P57772,P61254,Q16540,P62081,Q00839,Q8WU90,Q96PU8,Q13144,P46778,P50914,Q10713,Q96KC8,P53582,O60506,Q09161,P41567,P08865,P08670,P25398,P12270,P84098,Q13310,Q15650,P62917,Q4G176,P51116,Q9HCE1,P49458,P62899,Q9BW92,P46782,P29692,O95900,P04818,P53007,Q969T7,Q96G23,Q9NPI6,P61513,P55010,P50897,P62753,Q02543,Q53GQ0,Q7Z7H8,Q92552,P27635,Q9H074,P31483,P20042,Q9Y295,Q9Y3D3 73 +Sensory perception of pain 0.5604240173779489 0.8851873082271193 0.3760556163844182 1.0 0.6803822990087921 5 P27361 1 +Cell chemotaxis 0.3478025656245112 0.8844071961453127 0.376476439737645 1.0 0.6806268966792439 35 P14174,P26583,Q9BR76,P09429,O00429,P35613,P63000 7 +Fatty acid elongation 0.4690952523141335 0.8813325335430255 0.3781378621888629 1.0 0.6828244849597453 2 Q9P035 1 +Regulation of cell aging 0.4888016478924371 0.8802331997712591 0.3787329916836923 1.0 0.6833319059241848 11 P67809,P14174 2 +Regulation of lipopolysaccharide mediated signaling pathway 0.5177514976533806 0.8787001524323681 0.3795638759928019 1.0 0.6839623841676254 3 P14174 1 +Cytosolic calcium ion transport 0.3847803628457191 0.8754514962014396 0.3813282906361035 1.0 0.6859253249718205 24 P21796,P27695,P16615 3 +Vacuolar localization 0.4084190810956963 0.8751151718140162 0.3815112427273033 1.0 0.6859253249718205 19 Q96AX1,Q9H267,Q8NCA5,Q9UNH7,Q9H0B6,P09601,Q9UJ41,Q9UBN7,P35579 9 +Megakaryocyte differentiation 0.4521195740662347 0.8746819604403171 0.3817469782864928 1.0 0.6859253249718205 14 Q09472,Q15648,P26583,P48426,Q99873 5 +P38mapk cascade 0.5343530859049891 0.8717956370591701 0.3833198751746687 1.0 0.6869937463611536 7 P15311,Q12959 2 +Regulation of metaphase plate congression 0.5162098657118226 0.87165923845781 0.3833943034396754 1.0 0.6869937463611536 3 Q00839 1 +Skeletal muscle adaptation 0.515599692435966 0.8688750331357864 0.3849154868869338 1.0 0.6883964010479938 3 P16615 1 +Regulation of skeletal muscle adaptation 0.515599692435966 0.8688750331357864 0.3849154868869338 1.0 0.6883964010479938 3 P16615 1 +Defense response to gram positive bacterium 0.5564183726837024 0.867995817567654 0.3853966222764209 1.0 0.6890680430071021 5 Q96EE3 1 +Intracellular transport 0.2538523222755127 0.86731473429682 0.3857695857092826 1.0 0.6895459644861075 554 O60830,P24390,Q99595,O95376,Q15648,P09132,P49257,P83436,O75964,Q7L5D6,Q9NS69,Q96CS3,Q14108,Q99623,Q9Y282,P45880,Q9P0J0,Q13043,P07602,Q99816,O95070,Q9Y5M8,Q09161,Q8TDB6,P28288,P48426,Q9UBX3,Q92974,Q5JVF3,Q96EK5,O60725,Q9Y5L4,Q8TCT9,O14925,O15400,O76094,P14373,Q92544,Q9P2R3,P27361,P02545,P43307,P61960,Q8IUD2,Q96AX1,Q96D46,Q96GA3,O43615,P62841,Q96N67,Q9H2M9,Q9Y5J9,Q8WUX9,Q9UHB9,Q03001,P55735,O75381,P33908,P25705,Q13409,O75431,O75844,P24539,P46379,P61923,P15311,Q6P6C2,Q6NUQ1,Q16543,Q9Y3Y2,Q99747,P27695,Q10713,Q9HAV7,Q06481,Q4KMP7,Q9P2W9,P35241,P18859,P05455,Q9UNH7,P51159,P12235,Q9Y3B3,P26038,P16615,Q15075,P54619,Q8NEZ5,Q8N4H5,P50542,O60313,Q4J6C6,O43681,O14737,P36507,Q9H089,Q8IWJ2,Q9UPR3,Q9Y2L5,Q5SNT2,P17252,Q08379,Q9UJ41,Q15036,Q6P3W7,P51572,P40855,Q7Z392,Q9H267,Q9P260,Q14254,P61160,O60318,Q00839,Q12846,Q8TAT6,Q9Y5P4,P06576,P12270,P49458,P56134,Q9UIS9,Q9UJZ1,Q9Y4I1,Q86U42,P23786,Q9C0E2,Q8N1F7 129 +Positive regulation of innate immune response 0.3457364026250559 0.8661903708699978 0.3863857729947737 1.0 0.6902692457059659 35 Q09472,Q15648,Q13177,Q15233,Q9BY67,P26583,P09429,Q8WXF1,Q16512,Q9NUD5 10 +Mitochondrial fusion 0.4857044128157947 0.8642710821494627 0.3874389919677452 1.0 0.6917073244388864 11 O60313,Q9NX63,Q9Y6C9 3 +Cellular nitrogen compound catabolic process 0.2640420757615119 0.8630010511833737 0.3881368889935332 1.0 0.6926391407087226 171 Q7Z739,P67809,P30519,Q9Y2C4,Q9H773,Q9BQG2,Q9NRG1,Q14103,P13051,P09601,Q00839,Q13126,P51530,P53004,Q9Y3B2,P27695,Q09161,P08670,Q9UPR3,Q9HCE1,Q5JVF3,P51116,P17252,Q969Z0,P05455,Q969T7,Q9NPI6,Q96DE0 28 +Mitotic g2 m transition checkpoint 0.4154511201195962 0.8616840787510018 0.3888613892013017 1.0 0.6933632311277856 18 Q92547,Q99741,O14757,Q9NZM5,P54132,Q6NUQ1,P49959,Q96JB5,P53350,Q68E01 10 +Nucleotide excision repair dna incision 0.5627284782900208 0.8589120323819214 0.3903890504965965 1.0 0.6947583702047421 4 P18074 1 +Regulation of mitochondrial atp synthesis coupled electron transport 0.4643177067781462 0.8574120887472688 0.3912171806822186 1.0 0.695473527957548 2 P06493 1 +Anterograde dendritic transport 0.5621664893693369 0.856562100920389 0.3916869384748604 1.0 0.6959202905318518 4 Q14254 1 +Embryonic hemopoiesis 0.5621225898925322 0.8563785823687599 0.3917884075105766 1.0 0.6959202905318518 4 Q13043 1 +Formation of translation preinitiation complex 0.4951715252546263 0.855659573831811 0.3921861073472668 1.0 0.6964161748609483 10 P55010,Q9ULC4 2 +Lipoprotein biosynthetic process 0.4722385529162922 0.8541336301101438 0.3930309520719786 1.0 0.6971351279277442 12 Q96S52,P04062,Q92643 3 +Positive regulation of phospholipid biosynthetic process 0.5122461170848127 0.853599511381958 0.3933269293640746 1.0 0.6971351279277442 3 Q9UHD1,P17655 2 +Regulation of phosphatidylcholine biosynthetic process 0.5122461170848125 0.8535995113819571 0.3933269293640751 1.0 0.6971351279277442 3 Q8NF37,P17655 2 +Myeloid leukocyte activation 0.370039410536969 0.8510763417277353 0.394726946553531 1.0 0.6982351019127583 26 P14174,Q9UNH7,P09429,P09601,Q9UJ41,Q6NYC1 6 +Axo dendritic protein transport 0.5608165500340112 0.8509217980577398 0.3948127951852087 1.0 0.6982351019127583 4 P04792,P33176 2 +Protein localization to presynapse 0.5608165500340112 0.8509217980577398 0.3948127951852087 1.0 0.6982351019127583 4 P04792,P33176 2 +Regulation of phagocytosis 0.4136159132355072 0.8500866303180639 0.3952769241804872 1.0 0.6983154323773306 18 Q06481,Q8WTV0,P09429,P51159 4 +Cellular modified amino acid metabolic process 0.3082977183077688 0.847970416391474 0.3964544464825852 1.0 0.6998273512970925 56 P04818,O60568,Q15648,P34897,Q9H2D1,P12277,P23786,Q9H7Z7,P48651,Q9UHG3,P00390,P00374,O60725 13 +Myeloid leukocyte differentiation 0.3458893284291585 0.8457659743264142 0.3976833104822275 1.0 0.7006924855801505 34 Q00534,Q6IAN0,P04062,P17252,O00625 5 +Intrinsic apoptotic signaling pathway 0.2941224257385278 0.8445984298910112 0.3983350859987764 1.0 0.7009824955593927 80 Q9NR28,P45880,Q2TAL8,Q9P0J0,P14174,Q09472,Q9NYV6,Q15233,O60313,Q93034,P09601,P61254,P62081,P51572,O00429,Q96RU2,Q8IXB1,Q9NYF8 18 +Pyroptosis 0.5501413244302902 0.8411648374601777 0.4002555961412184 1.0 0.7033589626313421 5 Q96GX9 1 +Regulation of membrane protein ectodomain proteolysis 0.5584430439045995 0.8410202438632851 0.4003365935645422 1.0 0.7033589626313421 4 Q13464,Q9UKS6 2 +Phosphatidylcholine metabolic process 0.4574374252388324 0.8375484322900012 0.4022843651136993 1.0 0.7057278942827963 13 Q8WTV0,Q96N66,Q6IAN0 3 +Estrogen metabolic process 0.5407130823796695 0.8372085035148453 0.4024753784802413 1.0 0.7058732383665829 6 Q53GQ0,P51659,O95470 3 +Ph reduction 0.4453652458114063 0.8364010786092215 0.4029293060124801 1.0 0.7061000674106995 14 Q93050,P50897 2 +Membrane protein ectodomain proteolysis 0.5017989727086263 0.8356513051004562 0.4033510970063596 1.0 0.7063204288742364 9 Q8TCT9,Q9UKS6,Q13464 3 +Chaperone mediated protein folding 0.3382909185407908 0.8350202434838212 0.4037063105789082 1.0 0.7063204288742364 37 Q32P28,P40855,O14737,Q9H2J4 4 +Cytokine production involved in immune response 0.4364810246195046 0.8323252828315735 0.4052253634370879 1.0 0.7078428056184249 15 P09601 1 +Calcium ion regulated exocytosis 0.490416578951597 0.8320329049591768 0.4053903715551912 1.0 0.707941547971415 10 P35579,P16615,O14795 3 +Viral translation 0.4279260522901734 0.8311744733289625 0.4058750730992759 1.0 0.7083940953318001 16 Q15366,Q9ULC4 2 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.5069380212169567 0.8295182791018914 0.4068111977809887 1.0 0.7094735106143059 3 Q9NWT6 1 +Negative regulation of blood vessel endothelial cell migration 0.5471399021670005 0.8283855806811005 0.4074521699434004 1.0 0.7100167294192088 5 P51608,P09429 2 +Mast cell activation 0.5102776795357766 0.8271956906218314 0.4081261537974565 1.0 0.710248341248587 8 P09601,Q9UNH7 2 +Positive regulation of developmental growth 0.3597557876917976 0.8268451210363006 0.4083248518778857 1.0 0.71040468764465 28 P15311,Q96PU5,Q14651,Q9Y263 4 +Regulation of endocytosis 0.3147765720268374 0.825382522700763 0.4091544541622887 1.0 0.7105820111456326 50 Q96PU5,Q9UKS6,Q6P3W7,P50897,Q9UJ41,P50570,Q9P2R3,Q9UNF0,Q15036,Q06481,P63000 11 +Negative regulation of intrinsic apoptotic signaling pathway 0.3457879134998851 0.8253635809400348 0.4091652047170282 1.0 0.7105820111456326 33 P45880,P14174,Q9P0J0 3 +Regulation of mrna polyadenylation 0.4434025801691717 0.8253217146365499 0.4091889668840465 1.0 0.7105820111456326 14 P18615,Q09161,Q5VTR2 3 +Androgen metabolic process 0.5378218111519689 0.8246188392671039 0.4095880222839336 1.0 0.7110857763833336 6 O95470,P51659,Q15648 3 +Endoplasmic reticulum calcium ion homeostasis 0.5093445542978511 0.8228463710338827 0.4105953630563936 1.0 0.7117007828956666 8 P51572,P16615,Q9UM00 3 +Immune response regulating cell surface receptor signaling pathway 0.3454870669368948 0.8228042095531046 0.4106193424519853 1.0 0.7117007828956666 33 P46379,Q09472,Q13177,P15311,Q9NR50,Q9UJ41,Q13144,Q06481,Q16512,Q9UJZ1 10 +Regulation of hair cycle 0.5054195424662837 0.8226524518564926 0.4107056617200553 1.0 0.7117007828956666 3 Q13485 1 +Macrophage differentiation 0.4986797406831884 0.8206648530667419 0.4118371959021123 1.0 0.7131077832890587 9 P04062 1 +Regulation of neuron projection development 0.2987650731053755 0.8206504123461648 0.4118454237230251 1.0 0.7131077832890587 72 Q32P28,Q96PU5,P08670,Q9UQB8,Q14108 5 +T cell proliferation 0.3766905429036832 0.8169844120031242 0.4139373362423684 1.0 0.715401233134983 24 P26038,P09429,P62753,Q12959 4 +Regulation of biomineralization 0.5077740889895961 0.8155349997829905 0.4147661388785475 1.0 0.7162645732525539 8 Q9NUQ3,Q13464,O75116,Q4KMQ2,O75844 5 +Dna replication initiation 0.3707922642623841 0.8135388033804882 0.4159092081415814 1.0 0.7176688239904707 25 Q92547,P24941,P33992,O95251,P09884,P33991,Q9UBD5,Q14566,P25205 9 +Negative regulation of response to wounding 0.5347224370443409 0.8111598050712268 0.4172739050948699 1.0 0.7194529734872183 6 Q96G23 1 +Extrinsic apoptotic signaling pathway 0.3212414882928616 0.8079421902223459 0.4191238621857724 1.0 0.7216361153174594 45 Q9H0S4,Q9NR28,Q9P0J0,Q13043,P26583,P09601,Q12846,Q92974,P61289,P02545,P62136 11 +Regulation of cellular component movement 0.2706905881529564 0.8060354240959231 0.4202224239164056 1.0 0.7219971713431947 158 Q7Z739,P35221,Q96N67,P35240,Q13630,Q14344,P25705,Q16512,O00139,Q99996,P57076,Q8WTV0,P12814,Q96HY6,Q4VCS5,Q14185,Q12959,Q9Y263,Q00534,Q13043,P42345,P09601,Q4KMQ2,Q12846,P27695,Q9NWH9,P14174,Q13464,P19174,A0MZ66,P06576,P42785,Q92974,O00429,Q06481,P17252,P67870,P35241,P16949,O75122,Q96G23,Q5VTR2,Q9BR76,P09429,P16615,Q9UJ41,P27361,P02545,Q9UBN7,P26038,P51608,P63000 52 +Dna damage response signal transduction resulting in transcription 0.5333508998952644 0.8052164905699228 0.4206947619781429 1.0 0.722138471529407 6 Q01664,Q92993,P61254 3 +Protein catabolic process in the vacuole 0.5412367190708074 0.8033532769289027 0.4217705724125418 1.0 0.7233836414097892 5 P04062 1 +Lysosomal protein catabolic process 0.5412367190708074 0.8033532769289027 0.4217705724125418 1.0 0.7233836414097892 5 P04062 1 +Dicarboxylic acid metabolic process 0.3176405963300627 0.8013351141310499 0.4229376677849523 1.0 0.7251947503848132 47 Q9H2D1,Q4G176,P00374 3 +Gland morphogenesis 0.4733194279875564 0.8008759247097896 0.4232034790228738 1.0 0.7252694075901457 11 P15311,P26038,Q15648 3 +Trna modification 0.3403002241947004 0.7975549074330902 0.4251288275132898 1.0 0.7267983356811745 34 Q2VPK5,P05455,O60294,Q969Y2,Q9Y606,Q9NXG2,Q9BXR0,Q96FX7 8 +Embryo implantation 0.4831583441865141 0.7961703180025669 0.4259330472538924 1.0 0.7274745461410786 10 P35613 1 +Ventricular cardiac muscle cell action potential 0.5173795223215353 0.7953035440158126 0.4264369525081082 1.0 0.727876317768487 7 Q96PU5 1 +Axon development 0.2917190564643483 0.7945138245223663 0.4268963641081931 1.0 0.7281562133220251 84 P16949,Q96G23,O00264,P50570,Q9UQB8,Q06481,P35613,P63000,P00374,Q7KZI7 10 +Mitotic cell cycle process 0.2506075701092923 0.7914268773724406 0.4286949309277452 1.0 0.7303710091912003 273 P35580,Q96BK5,Q9UQE7,Q9UJX5,Q86XL3,Q93034,Q9NZM5,Q8WUX9,Q9UNZ2,Q6UVJ0,P50570,P42695,P23258,O95630,O00139,Q99623,P08183,Q9NVM9,O75844,O95235,P25205,Q12959,Q9BZD4,Q00534,P15927,O95067,P61254,Q6NUQ1,O14744,Q14141,Q14674,Q16763,Q00839,Q9UJX4,P51530,Q9H1A4,Q96JB5,Q9Y2S7,Q13561,P27695,Q6DKK2,O43663,Q13464,Q01082,P24941,P12270,O14757,O95905,Q5JVF3,P19447,Q06481,P61289,Q14566,Q9UJX2,Q9BW19,P17252,Q68E01,Q9NS87,P41227,P16949,P35241,P18074,Q08379,Q86XI2,O75122,P54132,P62753,Q96EE3,Q01664,P51608,Q9Y295 71 +Leukocyte chemotaxis 0.3585952057139021 0.7897314521732052 0.4296846189237628 1.0 0.7310154675436673 27 P14174,P09429,P35613 3 +Lymphocyte migration 0.4818076414171677 0.7895256668855309 0.4298048343495328 1.0 0.7310154675436673 10 P04062 1 +Phagocytosis 0.3217955265919142 0.7887728802051107 0.4302447628633914 1.0 0.7315730386780857 43 P09429,Q8WTV0,P51159,P50570,Q92544,Q06481,Q16512,Q6NYC1,P63000,Q9NWH9 10 +Defense response 0.2549711489076365 0.7880272033290112 0.4306807940152752 1.0 0.7319898284803215 229 Q7Z739,Q09472,Q15648,P34897,Q15233,Q9BY67,Q9NZM5,Q6IAN0,Q3LXA3,P04062,Q16512,Q99623,O75844,Q9Y263,Q01804,Q13177,P61160,O15111,P26583,P42345,P09601,Q4KMQ2,Q8WXF1,Q16543,Q15366,Q12846,Q9BQ95,Q8TAT6,P14174,O60506,P78362,Q09161,Q8TDB6,O94874,P19174,P08670,Q8IV08,Q9H078,P42785,Q92974,Q9HCE1,P23246,Q06481,Q9NVI7,Q14166,Q9UNH7,Q8NCG7,P09429,P51159,P14373,Q9UJ41,P27361,Q96EE3,Q01085,Q9NUD5,P51608,P63000 57 +Establishment of lymphocyte polarity 0.5455586358225482 0.7876407960729596 0.4309068447174953 1.0 0.7319898284803215 4 Q14254 1 +Protein kinase a signaling 0.4910558146399596 0.7842272734151201 0.4329067645656357 1.0 0.7347593096372792 9 P35241,P14174,P15311 3 +Regulation of defense response to virus 0.4199406790833008 0.7838360934250344 0.4331362922362505 1.0 0.7349577335241214 16 Q8TDB6,Q3LXA3 2 +Cellular component disassembly 0.2630251672646415 0.7828073056940215 0.4337402767847751 1.0 0.7354907879292526 167 Q96AX1,Q9Y2C4,P49815,P52789,Q8WUX9,P04062,P21796,O75381,Q8IYI6,O00139,Q99623,O75844,Q9UBB9,Q96HY6,P46199,Q99986,Q9H267,P52907,Q9ULC4,Q9Y3C8,P47755,Q99816,Q16543,O95140,Q9BQ67,Q96JB5,P29372,P17096,Q7KZI7,P33176,Q01082,O94874,Q96FZ7,Q92974,O00429,Q969G3,Q99661,Q9NYL9,P17252,Q9GZZ9,P35241,P16949,Q99570,Q08379,P51532,O75122,P12235,O15344,Q9UBN7,Q9UEY8,P62136,P61960,P16615,Q13813 54 +Striated muscle adaptation 0.5433472637135908 0.7785472240152841 0.4362464781077113 1.0 0.7386986289908989 4 P16615,Q13555 2 +Entry into host 0.3421989382105394 0.777979888304235 0.4365808697113431 1.0 0.7388814200560749 32 Q14108,P35613 2 +Citrulline biosynthetic process 0.495156102829663 0.7765386395747464 0.437431015475012 1.0 0.7395530588056809 3 Q05682 1 +Positive regulation of lipid metabolic process 0.4096259090763962 0.7718461816026638 0.4402055357781573 1.0 0.742135515852238 17 P16435,Q8NCG7,Q8WTV0,Q9UJZ1 4 +Neutrophil chemotaxis 0.4566070683349831 0.7717383689739156 0.4402694007979542 1.0 0.742135515852238 12 O00429,P35613 2 +Positive regulation of lipid biosynthetic process 0.478126238231622 0.7714649097880552 0.4404314137823875 1.0 0.742135515852238 10 P16435,Q8WTV0 2 +Multi organism reproductive process 0.2722725547035858 0.7704964763009639 0.4410054444491234 1.0 0.742135515852238 152 Q16181,Q7Z739,Q14997,Q15648,Q9BY67,Q9BPZ3,P51572,P50570,P54619,P35613,Q14157,Q9NVM9,Q15019,P45880,O14795,P26583,O95067,Q14141,Q96PU8,Q9Y2W6,P25490,O75718,P16104,P17252,P55769,Q9UHB7,Q9P0K7,P62753,P20042,Q9Y4C1,Q9BTX1 31 +Negative regulation of intracellular signal transduction 0.2917016154325811 0.7697217720718477 0.4414649522517138 1.0 0.7423302828177576 110 P35240,Q15233,Q3LXA3,P04062,O95630,Q12959,P45880,Q9P0J0,Q9NYV6,P15311,O60313,P54646,Q8TAT6,Q96JB5,Q9H3F6,Q10713,P14174,P16949,Q9UJ41 19 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4559971752025635 0.7685514104016733 0.4421596599477735 1.0 0.743119737527471 12 Q9H078,Q3LXA3,Q99623,Q8TAT6,Q9NUD5 5 +Astrocyte differentiation 0.4558657138638371 0.7678647679991616 0.4425675307412078 1.0 0.7435730206597776 12 P08670,Q13144,Q00534 3 +Positive regulation of protein localization to membrane 0.3556287902463881 0.7670493143272014 0.4430521958194333 1.0 0.7440449382186366 27 O14737,P15311,O00264,Q14651,Q12959 5 +Trna 5 end processing 0.5108932245405959 0.7664028030397443 0.4434366654774631 1.0 0.744116142686018 7 P05455 1 +Antiviral innate immune response 0.5320002123066542 0.7644808279058115 0.4445807575469569 1.0 0.745510788299436 5 Q9NVI7,Q9H078 2 +Er overload response 0.531073935252347 0.7606038334539867 0.4468937293900146 1.0 0.7487621252886354 5 Q9UM00 1 +Response to testosterone 0.4544013802370589 0.760223630198356 0.4471209224444243 1.0 0.7489504979138382 12 P04062,Q13126 2 +Peroxisome organization 0.4752785278091842 0.7575460443610404 0.4487227913348599 1.0 0.7506703245965896 10 O00429,O75381,P40855,P50542 4 +Proton transmembrane transport 0.3205177739569626 0.7570135596179062 0.4490417388432832 1.0 0.7510113756256449 41 P18859,Q9UJZ1,P06576,P14854,P12235,Q9UDW1,O75964,P56134,P25705,Q99623,P24539 11 +Potassium ion transport 0.3731639664423175 0.756338570446229 0.4494462284145299 1.0 0.7511103935040263 23 Q96PU5,Q99996,P24941,Q12959 4 +Amyloid precursor protein metabolic process 0.4151042901691079 0.7553727329766483 0.4500253690354499 1.0 0.75188570361632 16 Q12959,Q15392 2 +Release of cytochrome c from mitochondria 0.464132394916846 0.7543681066411405 0.4506282169195961 1.0 0.7523151045324339 11 O00429,O60313,Q96A26 3 +Negative regulation of cell cell adhesion 0.3858301283890716 0.7535342994811717 0.4511289081372864 1.0 0.7526277517722143 20 P35241,P09429,Q12959 3 +Regulation of leukocyte proliferation 0.3727531514481338 0.7534800889731239 0.4511614717948058 1.0 0.7526277517722143 23 P14174,P09429,Q16512,Q96EY1,Q12959 5 +Positive regulation of peptidase activity 0.3191049444478236 0.7527359670821512 0.4516085920741819 1.0 0.7529833016295666 42 Q9NR28,Q14997,Q9P0J0,O14737,P09429,P51572,Q96HY6,Q96A26 8 +Peptidyl glutamic acid modification 0.5288034680416691 0.7511179687326764 0.452581662631641 1.0 0.7539335831689662 5 P41227 1 +Cellular response to estradiol stimulus 0.5278154890403912 0.7469980797244964 0.4550647199693016 1.0 0.7564320841873822 5 Q92993 1 +Positive regulation of cilium assembly 0.5195760174586799 0.7459920833460337 0.4556721973408391 1.0 0.7569806997968671 6 P27695 1 +Bleb assembly 0.4879958732481328 0.7446976237714864 0.4564545359970759 1.0 0.7577772327440646 3 Q4KMQ2 1 +Positive regulation of endothelial cell migration 0.3712659680749351 0.7431457735535272 0.4573934294862476 1.0 0.759142807941824 23 P09429,Q8WTV0,P09601,P63000,P17252,Q9NWH9 6 +Synaptic vesicle endosomal processing 0.5344439754496604 0.7421587927380813 0.4579911319179937 1.0 0.7599415527324758 4 Q15075 1 +Astrocyte development 0.5185806031974302 0.7417477096930116 0.4582402075469041 1.0 0.7601423122739658 6 P08670,Q00534 2 +Small nucleolar ribonucleoprotein complex assembly 0.5341638894970302 0.741020151370761 0.4586812220382366 1.0 0.7603133490021672 4 P55769 1 +Rna modification 0.2953731519503078 0.740440877870724 0.4590325227290279 1.0 0.7607024487886328 65 O95900,Q2VPK5,P05455,O60294,Q969Y2,Q9Y606,Q6P6C2,Q9NXG2,Q96CB9,Q96DE0,Q6NYC1,Q96HR8,Q9BXR0,Q9UBS4,Q9NNW5,Q96FX7,Q9UJK0 17 +Positive regulation of cysteine type endopeptidase activity 0.3408698603704146 0.7392496901517291 0.4597553926353219 1.0 0.7613750492481701 30 Q9NR28,Q9P0J0,O14737,P09429,P51572,Q96F07,Q01664,P63167,Q9BXK5,Q9NZJ7,Q14790,Q96A26 12 +Atp biosynthetic process 0.3835818129354742 0.7388894918408996 0.4599741036865663 1.0 0.7614893456769487 20 P18859,P06576,O75964,P56134,P25705,Q9UJZ1 6 +Positive regulation of mitochondrion organization 0.387208872142835 0.7382017809271926 0.4603918408236058 1.0 0.7617944100443336 19 O00429,P21796,P12235,Q96A26 4 +Positive regulation of erythrocyte differentiation 0.4389695884430787 0.7375445263536607 0.4607912760701804 1.0 0.7622620703761718 13 Q99873,P26583,O95251,Q15648 4 +Fc receptor mediated stimulatory signaling pathway 0.5174528968752962 0.736945420285587 0.4611555412880614 1.0 0.7626037984645998 6 Q9UJ41,Q06481 2 +Plasma membrane tubulation 0.516918208072897 0.7346707867649315 0.462540015885297 1.0 0.7636064112490383 6 Q9UNF0,Q9UKS6 2 +Tubulin deacetylation 0.4600731434725151 0.7339805420268795 0.4629605971739663 1.0 0.7637778027923634 11 Q09472,P49354 2 +Primary mirna processing 0.523909145248051 0.7307564414295795 0.4649279338156673 1.0 0.7649416433842157 5 P40763,Q9BXP5,P22626,O00571 4 +Maintenance of synapse structure 0.5157555820526827 0.7297300330694273 0.4655552194490178 1.0 0.765293038318461 6 Q8IUD2 1 +L kynurenine metabolic process 0.4377426097342515 0.7267577016257445 0.4673743989067733 1.0 0.7669523646447185 2 Q6YP21 1 +Kynurenine metabolic process 0.4377426097342515 0.7267577016257445 0.4673743989067733 1.0 0.7669523646447185 2 Q6YP21 1 +Regulation of transport 0.2362615271646301 0.7254901617351449 0.4681513783088573 1.0 0.7675774476814959 317 P35580,O95376,Q32P28,P35754,P49257,Q13555,Q6P3W7,P51572,P50570,P21796,P30533,Q99996,Q99623,P08183,Q8WTV0,Q15019,Q12959,Q9Y282,Q9Y263,O14795,P15311,P09601,Q16850,Q12846,P27695,Q4J6C6,P14174,Q96KC8,O14737,P00367,P36507,Q96PU5,P12270,Q9UKS6,Q8IWJ2,O00429,Q06481,Q9P2W9,P17252,Q9UIS9,P35241,Q9C0E2,O75122,P46939,Q9UNH7,P26038,P09429,P51159,P50897,Q9UJ41,Q92544,Q9P2R3,Q9UNF0,Q15036,P61960,P53985,P16615,P63000 58 +Granulocyte chemotaxis 0.4177644140785352 0.7249576543762393 0.4684780091151697 1.0 0.7675774476814959 15 O00429,P35613 2 +Dna replication checkpoint signaling 0.5141667836659942 0.7229898852114606 0.4696860984607329 1.0 0.7687914418246158 6 P51530,Q99741,Q9UNS1,Q92547 4 +Hippo signaling 0.477890657998246 0.7220326793601739 0.4702743859887035 1.0 0.7694217131743978 9 Q4VCS5,Q13043,P35240 3 +Multicellular organismal signaling 0.3631705075359106 0.7204965217391481 0.4712193405229961 1.0 0.7702360415787807 24 Q99996,P04062,P16615 3 +Sulfur compound metabolic process 0.2889108653356614 0.7203951146063565 0.4712817571058219 1.0 0.7702360415787807 103 P53007,Q9H7Z7,O76071,Q9UBX3,P50897,Q9Y6N5,Q4G176,Q13126,O60725 9 +Neurotrophin trk receptor signaling pathway 0.5135040065065593 0.7201822384816501 0.4714127982275218 1.0 0.7702360415787807 6 P27695 1 +Exit from mitosis 0.4352017343093967 0.7174162988602371 0.4731172656557381 1.0 0.7715050663841446 13 P83731,O75122,Q8WUX9,Q16763,Q99623,Q9UJX2 6 +Establishment or maintenance of monopolar cell polarity 0.4566229301782314 0.7167368704964623 0.4735364710609304 1.0 0.7717183438563446 11 P15311 1 +Sensory perception of mechanical stimulus 0.4239309804755708 0.7167051777189881 0.4735560304014667 1.0 0.7717183438563446 14 Q14108,Q9Y5L4 2 +Dna dependent dna replication 0.2854071577261357 0.716002968065464 0.4739895162147349 1.0 0.7717183438563446 83 P49959,Q04837,Q7Z7L1,O75844,Q9BRT9,P25205,P28340,Q9NR33,P51530,Q9Y2S7,P17096,P46063,P78362,P24941,O95251,Q96RR1,Q9Y3Z3,Q9BUQ8,P33991,Q9UBD5,Q96EY1,Q14566,Q9UJZ1,Q92547,P33992,P54132,P09884,Q9UNS1,Q8WVB6 29 +Organic acid biosynthetic process 0.2856975248818629 0.7153737151426551 0.4743781498223642 1.0 0.7717183438563446 84 Q05682,P14174,O60568,P00367,P34897,Q8NCG7,Q9H7Z7,P29373,A1L0T0,Q96C36,Q96GX9,P54646,Q53GQ0,Q4G176,Q96PU8,P54619,Q13126,P00374 18 +Negative regulation of leukocyte proliferation 0.4992878385658844 0.7152308109458543 0.4744664334291255 1.0 0.7717183438563446 7 Q12959 1 +Er nucleus signaling pathway 0.4344632853092495 0.7134838282364342 0.475546416675999 1.0 0.7723782765623619 13 P16615,Q96A33,Q9UM00 3 +Vesicle mediated transport between endosomal compartments 0.3756456648872319 0.7129767970750981 0.4758601151863524 1.0 0.7725032616184417 21 P15311,Q15075,P26038,P35241 4 +Cellular response to peptide hormone stimulus 0.2921905184813569 0.7109447264057275 0.4771184884254613 1.0 0.7735212637072125 67 P43490,P27695,Q9UQB8,Q9BSK2 4 +Protein targeting to lysosome 0.4553241288158833 0.7102668062631287 0.4775386998000581 1.0 0.7738354403501688 11 Q14108 1 +Lipopolysaccharide mediated signaling pathway 0.4651799557274204 0.7085839203256122 0.4785827176169448 1.0 0.7745396319407882 10 P14174,Q8WTV0 2 +Chondroitin sulfate proteoglycan metabolic process 0.4338608539862621 0.7080812665672321 0.4788947923507631 1.0 0.7745396319407882 2 Q96L58 1 +Chondroitin sulfate proteoglycan biosynthetic process 0.4338608539862621 0.7080812665672321 0.4788947923507631 1.0 0.7745396319407882 2 Q96L58 1 +Chondroitin sulfate biosynthetic process 0.4338608539862621 0.7080812665672321 0.4788947923507631 1.0 0.7745396319407882 2 Q96L58 1 +Regulation of oxidative phosphorylation 0.4745347377604783 0.7063443941123532 0.4799739919418373 1.0 0.7759824591521145 9 Q9BSK2,P34897 2 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.517939054758281 0.7060886937532891 0.4801329823745932 1.0 0.7759824591521145 5 P14174 1 +Regulation of glial cell proliferation 0.5251205371358199 0.7044708975508577 0.4811395676142642 1.0 0.7770011021601808 4 Q96G23 1 +Cardiac muscle cell action potential 0.3902236686622783 0.704275695621635 0.4812610989738819 1.0 0.7770011021601808 18 Q96PU5,Q99996,Q12959 3 +Regulation of chemotaxis 0.3472024809369572 0.7031510928290862 0.4819615941848423 1.0 0.7770995194979183 27 P14174,Q9BR76,P09429,O00429,Q12846,P63000 6 +Positive regulation of leukocyte proliferation 0.4323921438763052 0.7024768084216343 0.4823818597899829 1.0 0.7770995194979183 13 P14174 1 +Columnar cuboidal epithelial cell development 0.496332339661117 0.7023200997958423 0.4824795611077697 1.0 0.7770995194979183 7 Q00534 1 +Regulation of g protein coupled receptor signaling pathway 0.4322827127876515 0.7018961752861586 0.4827439143166434 1.0 0.7771057683350802 13 P16949,O14744,P50570,P17252,Q9NWH9 5 +Positive regulation of atp dependent activity 0.3696209372307634 0.7008666796934412 0.4833862203752994 1.0 0.7773947628058517 22 Q8WXX5,O95433,Q00839,P50570,Q5JTV8,P20585,Q8IXB1,Q04837,Q9Y3Y2,Q9UBS4 10 +Regulation of sodium ion transmembrane transport 0.3976834918400164 0.7001065962117593 0.4838607367570475 1.0 0.7779441163036442 17 Q96PU5,P50570,P46939,Q12959 4 +Regulation of fc receptor mediated stimulatory signaling pathway 0.523803958283898 0.6991861223304511 0.484435722209918 1.0 0.7784849847677727 4 Q06481 1 +Adenylate cyclase activating dopamine receptor signaling pathway 0.4317706778142759 0.6980748197147099 0.4851304044187048 1.0 0.7790258413475559 2 O14745 1 +Negative regulation of growth 0.3283548669547762 0.6958344985795886 0.4865324816320973 1.0 0.7807010019992787 34 Q9P0J0,Q13043 2 +B cell differentiation 0.4410076590732094 0.6910079488920018 0.4895605457448801 1.0 0.7845953147178506 12 Q5JVF3,P25490 2 +Myeloid cell development 0.3758772569246493 0.6890665402426652 0.4907813949460484 1.0 0.7850096527985078 20 P18074,Q09472,Q15648,P48426,P62753,Q6NYC1 6 +Prenylation 0.5135198808709701 0.6879565554017697 0.4914801401648718 1.0 0.7859346715795035 5 P49354 1 +Response to camp 0.4505514669844269 0.6865956976514338 0.4923375404170578 1.0 0.7863423369460889 11 P15311,Q99996,P35613 3 +Nerve development 0.4793255333746465 0.6852837188225658 0.4931649036370702 1.0 0.7870858794657667 8 Q9H061 1 +Positive regulation of gene expression 0.2501187338361409 0.6833840317746863 0.4943642075332117 1.0 0.7881705199077346 231 Q7Z739,P67809,Q09472,Q15648,P23381,Q9BY67,Q52LJ0,Q567V2,P54619,Q96FZ2,Q99623,Q96HY6,Q00534,P15311,O15111,P26583,P42345,Q14103,P09601,P61254,Q9H2J4,Q00839,P62081,Q12846,Q96PU8,Q13144,Q96AE4,P14174,O60506,O14737,Q09161,P78362,P25490,P36507,P08670,Q13595,O14757,Q92974,P51116,Q9UJZ1,O95900,P35241,P09429,P51159,P14373,P27361,P02545,Q9NUD5,Q92552,Q8WVV9,Q9H074,P26038 52 +Positive regulation of growth 0.2959391739225213 0.6832508006643992 0.4944483770306873 1.0 0.7881705199077346 54 Q6PJG6,Q9Y263,Q09161,P15311,Q96PU5,Q14651,Q9BSK2 7 +3 utr mediated mrna destabilization 0.503631644098537 0.6786577925158087 0.4973547153473037 1.0 0.7920328563670244 6 Q14103,Q9HCE1 2 +Positive regulation of proteolysis 0.2845449036539929 0.6784994526146029 0.4974550707757688 1.0 0.7920328563670244 90 Q14997,O95376,Q9BXI6,P62191,Q9NZM5,Q8IXJ6,P51572,Q6ZXV5,P04062,Q8NEZ5,Q96HY6,Q9Y5A7,P46379,Q9P0J0,O75116,Q96F07,O60826,Q9BXK5,Q96JB5,Q96A26,Q9NR28,O14737,Q9UKS6,P61289,P35579,Q9NZJ7,P09429,Q01664,P63167,P54725,Q14790 31 +Interferon gamma mediated signaling pathway 0.5111153177252661 0.6781383569681876 0.4976839726117656 1.0 0.7920328563670244 5 Q15648 1 +Negative regulation of ubiquitin protein ligase activity 0.4684040420166155 0.677877676490432 0.4978492551966444 1.0 0.7920328563670244 9 Q13257,P62913,P62841,P62081 4 +Microtubule anchoring at microtubule organizing center 0.5109323242257802 0.677392585752767 0.4981569012417703 1.0 0.7920328563670244 5 Q9Y496,Q9UIS9 2 +Microtubule anchoring at centrosome 0.5109323242257802 0.677392585752767 0.4981569012417703 1.0 0.7920328563670244 5 Q9Y496,Q9UIS9 2 +Fc gamma receptor signaling pathway 0.5179927322871956 0.675976882860297 0.4990553223673335 1.0 0.792996112434677 4 Q06481 1 +Regulation of actin filament based movement 0.4677016811866129 0.6746330812041452 0.499908909930459 1.0 0.7934335658148284 9 Q99996,Q12959 2 +Response to hormone 0.2473625452946544 0.6743951794053464 0.5000601066804151 1.0 0.7934335658148284 198 Q09472,P43490,Q15648,P04062,Q9UQB8,Q16512,P35613,Q99623,Q96HY6,Q15392,P16435,P26583,P42345,P09601,P54646,Q00839,Q13144,P27695,O15173,P25490,P35573,O94874,Q15650,P42785,O43347,Q06481,Q9BSK2,P17252,P35241,Q9Y4I1,P04818,P61960,Q9Y4C1,Q9NS86,Q9NUQ7 35 +Positive regulation of protein polymerization 0.3275452681469191 0.6722167286396696 0.5014457327199522 1.0 0.7950521991570476 33 P30622,P42345,Q9Y295,Q9UQB8,Q16512,P63000,Q99996,P51608,Q9NWH9,Q12959 10 +Response to reactive oxygen species 0.3233184230298314 0.6718000969792387 0.5017109670005317 1.0 0.7950596334763962 35 O15111,P09601,P00374 3 +Response to lectin 0.5019022716549554 0.6714439733088305 0.5019377397981539 1.0 0.7950596334763962 6 Q09472,Q16512 2 +Innate immune response activating signal transduction 0.5019022716549554 0.6714439733088305 0.5019377397981539 1.0 0.7950596334763962 6 Q09472,Q16512 2 +Bone mineralization 0.4667945810771887 0.6704479327222822 0.5025722874558676 1.0 0.7958715719332666 9 P18074,Q4KMQ2,O75844 3 +Intestinal absorption 0.4664501223420686 0.6688602444322508 0.5035846323759277 1.0 0.7966081131650736 9 P15311,Q8WTV0 2 +Ribosomal small subunit assembly 0.4151516650834659 0.6686609524313941 0.5037117813429379 1.0 0.7966081131650736 14 P46782,P62841 2 +Respiratory chain complex iv assembly 0.4705136048240216 0.6682869684929428 0.5039504300861977 1.0 0.7966081131650736 3 O43819 1 +Mitochondrial cytochrome c oxidase assembly 0.4705136048240216 0.6682869684929428 0.5039504300861977 1.0 0.7966081131650736 3 O43819 1 +Muscle hypertrophy in response to stress 0.4704905249284558 0.6681874760910443 0.5040139287861767 1.0 0.7966081131650736 3 P16615 1 +Axonal transport of mitochondrion 0.5080602066443671 0.6657144178379125 0.5055936561331873 1.0 0.7987180343561319 5 P27695 1 +Neuron development 0.2462585086229005 0.6644775395570846 0.5063847196391686 1.0 0.7989020137260655 194 Q09472,Q32P28,Q6P3W7,P50570,P04062,Q14651,P42892,Q9UQB8,P35613,Q14108,P00374,Q9Y263,Q7KZI7,Q96PU5,P08670,Q99873,Q9HCE1,Q06481,P16949,O94887,Q96G23,O00264,P09429,P50897,P63000 25 +Peptide biosynthetic process 0.2390207378449914 0.6642905669645953 0.5065043572906047 1.0 0.7989020137260655 356 Q7Z739,P67809,Q8N5C6,Q9Y285,P62841,P34897,P23381,Q9BPZ3,Q96EY7,Q567V2,O75879,P00374,P46199,Q9BTE6,Q9HA77,Q15024,Q9ULC4,Q14103,P42345,P57772,P61254,Q16540,P62081,Q00839,Q8WU90,Q96PU8,Q13144,P46778,P50914,Q10713,Q96KC8,P53582,O60506,Q09161,P41567,P08865,P08670,P25398,P12270,P84098,Q13310,Q15650,P62917,Q9HCE1,P51116,P49458,P62899,Q9BW92,P46782,P29692,O95900,P04818,Q969T7,Q9NPI6,P61513,P55010,Q02543,P62753,Q7Z7H8,Q92552,P27635,Q9H074,P31483,P20042,Q9Y295,Q9Y3D3 66 +Protein targeting to membrane 0.322431036537483 0.6642611035138115 0.5065232113452898 1.0 0.7989020137260655 35 O43681,P50542,P09132,O76094,Q9UHB9,P49458,Q9UJ41,Q7L5D6,P43307,P40855,O60725 11 +Protein lipid complex assembly 0.514953834709194 0.6639189593851136 0.5067421809517549 1.0 0.7989020137260655 4 P17252 1 +Tetrapyrrole biosynthetic process 0.4356573243793984 0.6637367763269698 0.5068587970027512 1.0 0.7989020137260655 12 P36551 1 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4694509492886229 0.6637101661907754 0.5068758314299797 1.0 0.7989020137260655 3 P61254 1 +Organelle localization 0.2484252748124785 0.6623285277655335 0.507760697777742 1.0 0.79943216253258 177 Q96AX1,Q96D46,Q96GA3,Q96BK5,Q96N67,P62841,P48444,Q8WUX9,Q9UNZ2,P50570,O75381,Q8WXH0,Q99996,Q12959,Q96EA4,Q6PJG6,Q9BZD4,Q9H267,O14795,P15311,P61160,P42345,O60313,P09601,Q13257,Q14674,O15498,Q99816,Q00839,O75153,O95140,Q12846,P27695,Q13561,Q7KZI7,P33176,Q96FZ7,O60763,Q9H089,Q9H0B6,O00429,Q99661,Q5SNT2,P35579,Q9UJX2,Q9BW19,Q9P253,Q9UIS9,Q9Y4I1,Q9Y496,O75122,Q8NCA5,Q9UNH7,O15400,P51159,Q9UJ41,Q9UBN7,P02545,Q96EE3,P49755,P16615 61 +Positive regulation of peptidyl serine phosphorylation 0.3833167219220417 0.6621168441570526 0.5078963415259661 1.0 0.7994528520980353 18 P14174,Q13043 2 +Regulation of cardiac muscle cell action potential 0.464807048724949 0.661298944186542 0.5084206184400717 1.0 0.799822653628506 9 Q99996,Q12959 2 +Regulation of atp metabolic process 0.3414912505876682 0.6603551439421784 0.5090259503830035 1.0 0.8002658039507301 27 Q09472,P34897,P54646,O00429,P54619,Q9BSK2 6 +Cytoplasmic translation 0.2828933869888959 0.6587408624833266 0.5100621882743064 1.0 0.8014102623691534 115 P67809,P62841,Q9NR50,P61247,Q9ULC4,Q14103,P42345,Q7Z478,P61254,P62081,Q00839,P46778,Q8WU90,P50914,O60506,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,Q9H2U1,P61513,P55010,Q02543,P62753,P15880,P46776,P27635,Q9H074,P20042,Q9Y295 34 +Regulation of striated muscle cell differentiation 0.4344643730918805 0.6576886667963981 0.5107382062542276 1.0 0.8021847253947266 12 P67809,Q8NEZ5,P25490 3 +Defense response to other organism 0.2539340871203669 0.6572865015956968 0.510996714252113 1.0 0.802254213630244 170 Q7Z739,Q09472,Q15648,P34897,Q15233,Q9BY67,Q9NZM5,Q3LXA3,Q16512,O75844,Q99623,Q01804,Q13177,P61160,O15111,P26583,Q12846,Q8WXF1,Q15366,Q8TAT6,Q9BQ95,P14174,O60506,P78362,Q09161,Q8TDB6,P08670,Q9H078,Q92974,Q9HCE1,Q06481,Q14166,P09429,P51159,P14373,P27361,Q96EE3,Q9NUD5,Q9NVI7 39 +Regulation of potassium ion transport 0.3980296188707312 0.6564010391412743 0.5115661220190661 1.0 0.8029053661126564 16 Q96PU5,Q99996,Q12959 3 +Regulation of transporter activity 0.3030434777689961 0.6560207665263124 0.511810762735996 1.0 0.8030961860098845 47 P46939,P17252,P35754,Q96PU5,P50570,Q99996,Q99623,P08183,P27695,Q12959 10 +Organ growth 0.3582885037686419 0.6539785319234932 0.5131256367836332 1.0 0.8041925806075866 23 Q13043 1 +Regulation of pattern recognition receptor signaling pathway 0.36942237689841 0.6478067193233371 0.5171099688997123 1.0 0.8081138815323435 20 Q14254,P09429,Q9NZM5,Q3LXA3,Q06481,Q8TAT6,Q9NUD5 7 +Exocytosis 0.2851111942573318 0.6475667415106909 0.517265214140834 1.0 0.808157239043113 71 P51151,Q8IYI6,Q16512,Q68EM7,Q7Z392,Q15019,O14795,P09601,O15498,Q99816,Q12846,P27695,Q4J6C6,Q96FZ7,Q8TBQ9,Q9UPT5,P35579,O43760,O75122,Q9UNH7,P51159,Q9UJ41,P49755,P16615 24 +Sulfur amino acid metabolic process 0.4324156441884943 0.647330674352044 0.517417953062024 1.0 0.8082023843185181 12 Q13126 1 +Peptidyl serine modification 0.2803924085029029 0.6447952299850613 0.5190598935004855 1.0 0.8090243288713085 78 Q9BV86,Q10472,P14174,P78362,P24941,Q13043,Q9NWY4,O15111,P36507,P42345,P17252,P54646,Q16512,Q99996,Q7KZI7,P41227 16 +Striated muscle contraction 0.3360437385316098 0.6437222618528782 0.5197555513861514 1.0 0.8096617960160983 28 Q96PU5,Q99996,P16615,Q9Y4J8,Q12959 5 +Trna 3 end processing 0.5025835043362386 0.6435903866866992 0.5198410857044824 1.0 0.8096617960160983 5 P05455 1 +Regulation of cellular macromolecule biosynthetic process 0.2432147133587488 0.6403697899054505 0.5219322183494755 1.0 0.811756352942964 278 Q7Z739,P67809,Q96BK5,Q9UQE7,P34897,Q9BPZ3,Q96EY7,Q567V2,P04062,Q04837,Q9BRT9,P00374,P46199,Q15024,Q14103,P42345,P57772,P61254,Q00839,Q96PU8,Q13144,P51530,Q96HR8,Q10713,Q96KC8,P53582,P24941,Q09161,P41567,P25490,P08670,O14757,P12270,Q99873,Q9UPR3,Q9HCE1,P51116,P49458,Q9UBD5,Q9UJZ1,O95900,P04818,Q08379,Q969T7,Q9NPI6,Q96EZ8,P55010,P54132,Q92552,P27635,Q9H074,P31483 52 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.4204907976087634 0.639921050237647 0.5222239278594163 1.0 0.8118230950954146 13 P14174 1 +Positive regulation of telomere capping 0.5015262250580665 0.6393419402028631 0.522600510272742 1.0 0.8122150345415371 5 Q14103 1 +Glycosylation 0.2998252195656806 0.6385317104159169 0.5231276187638443 1.0 0.8127411460157636 48 Q10472,Q9Y673,Q08379,O60568,O60502,Q9NR45,P83436,Q6ZXV5,Q9Y5P6,P04062,P33908,Q9H6U8,Q2TAA5 13 +Negative regulation of defense response 0.3230781439577381 0.635488514571688 0.5251098551675506 1.0 0.8136958600768948 33 Q7Z739,Q3LXA3,Q9UJ41,P04062,Q15366,Q14166 6 +Smad protein signal transduction 0.4679088780066387 0.6344310448556179 0.5257995546236585 1.0 0.8140849094837473 8 Q13485,P08670,Q01082,Q8N1F7 4 +Regulation of developmental growth 0.2888329876332733 0.6341386986649863 0.5259903093944067 1.0 0.814124048516219 56 Q9Y263,P50542,Q13043,P15311,P25490,Q96PU5,Q14651 7 +Snorna localization 0.4620270511147218 0.6319760250954428 0.5274025435230822 1.0 0.8150198908433897 3 Q8WWY3 1 +Organic hydroxy compound biosynthetic process 0.2885412370932623 0.6310048730458958 0.5280373381832635 1.0 0.8155674021152988 56 P37268,Q13907,Q15125,Q15126,P04062,Q16850,P00374,Q15800,Q15392 9 +Regulation of lymphocyte differentiation 0.3667145204856608 0.6306435839084108 0.5282735945731345 1.0 0.8155934417280046 20 O43290,Q5JVF3,P09429 3 +Regulation of exocytosis 0.3050948224760523 0.6302475750037174 0.5285326169685356 1.0 0.8158003449235249 43 O75122,P09601,P51159,Q9UJ41,Q12846,Q15019,P16615,P27695,Q4J6C6 9 +Rho protein signal transduction 0.3270902031668303 0.6296003629828074 0.5289560860366613 1.0 0.816260916877572 30 P16949,Q13464,Q13618,A0MZ66,Q13017,O75116,O75955,Q14344,Q92974,Q92888,P63167,Q9H3F6,Q07960,Q9NWH9,P63000 15 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.4915391822138414 0.6286252818790723 0.5295944048095571 1.0 0.8164736796095369 6 Q15006 1 +Protein o linked glycosylation 0.4076323681216787 0.6280698044766626 0.5299582128076075 1.0 0.8165803808730998 14 Q6ZXV5,O60502,O60568 3 +Regulation of lamellipodium morphogenesis 0.4609933707632276 0.627592035011832 0.5302712278144899 1.0 0.8165803808730998 3 Q9BR76 1 +Positive regulation of lamellipodium morphogenesis 0.4609933707632276 0.627592035011832 0.5302712278144899 1.0 0.8165803808730998 3 Q9BR76 1 +Regulation of sodium ion transport 0.3696100564928841 0.6275645292476194 0.5302892513239652 1.0 0.8165803808730998 19 Q96PU5,P50570,P46939,Q12959 4 +Positive regulation of ion transport 0.3056176112070425 0.6265377907124737 0.5309622575822586 1.0 0.8174238483089926 42 Q99996,P14174,P08183,Q12959 4 +Regulation of myeloid leukocyte mediated immunity 0.4279988224955388 0.6251284617853061 0.5318867491944252 1.0 0.8178438559024613 12 Q9UJ41,P09601 2 +Regulation of synaptic vesicle recycling 0.4906649755044704 0.6250469016239375 0.5319402759839047 1.0 0.8178438559024613 6 Q9Y263 1 +Positive regulation of t cell cytokine production 0.4602747909199359 0.6245495866025489 0.5322667158940364 1.0 0.8178438559024613 3 P04439,Q12933 2 +T cell cytokine production 0.4602747909199359 0.6245495866025489 0.5322667158940364 1.0 0.8178438559024613 3 P04439,Q12933 2 +Dna topological change 0.478043755410005 0.6236856369347186 0.5328340575805779 1.0 0.8178438559024613 7 P09429 1 +Cell activation 0.2664900711319847 0.623639677587507 0.5328642469042699 1.0 0.8178438559024613 146 Q09472,P24390,Q9BY67,P04062,Q16512,Q96FZ2,Q99623,Q12959,Q00534,Q14254,P13051,P42345,P09601,Q12846,P14174,P53582,P25490,O43290,Q5JVF3,P17252,Q9UJZ1,O96005,Q9UNH7,P09429,P51159,P62753,Q9UJ41,Q6NYC1,P26038 29 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.4472143288462155 0.6232600629376652 0.5331136375267329 1.0 0.818034234305069 10 P14174,Q9NYV6,P62081 3 +Negative regulation of endoplasmic reticulum unfolded protein response 0.4974317475319671 0.622960915477075 0.5333102062162589 1.0 0.8181434898371663 5 Q96HY6 1 +Negative regulation of chemotaxis 0.4900249123803663 0.6224304130060092 0.5336588875115855 1.0 0.8181735008872348 6 P14174 1 +Negative regulation of binding 0.3081728288672762 0.6217272364443057 0.534121239100926 1.0 0.8184512520279843 40 O14981,Q08379,P09601,Q6IAN0,P27361,O75381,P40855,P30533,P62136,P16615,Q9UBB9 11 +Limbic system development 0.3651762982044536 0.6209348153103463 0.5346425129338606 1.0 0.818647827171838 20 P27695,Q00534,P35240 3 +Regulation of mitochondrial membrane permeability 0.4164135121141529 0.6187877513663146 0.5360561923566425 1.0 0.8206199182077055 13 P45880 1 +Gpi anchor metabolic process 0.4587960158009785 0.61830195342512 0.5363763144781368 1.0 0.8209174081342216 3 Q92643 1 +Neutrophil migration 0.4055923622969359 0.6171548040614802 0.5371326232856171 1.0 0.821882180436562 14 O00429,P35613 2 +Muscle adaptation 0.367526391071714 0.6146964381680894 0.5387552125163875 1.0 0.8239785603191808 19 Q13464,P25490,Q13485,O75116,P09601,Q13555,P02545,P09874,P17252,Q13557,P16615 11 +Erythrocyte development 0.434762591667363 0.6095849027304004 0.542136814992666 1.0 0.8270184325951703 11 P18074,Q15648,Q9NRK6,P62753,Q6NYC1 5 +Attachment of spindle microtubules to kinetochore 0.3664728526709197 0.608211142914603 0.5430474451566321 1.0 0.8275631693188192 19 Q9BZD4,Q00839,Q99661,Q96EE3,Q9H8V3 5 +Prostanoid metabolic process 0.4037854586516906 0.6075237717759419 0.5435033716461817 1.0 0.8275631693188192 14 Q9H7Z7,Q8NCG7,P14174 3 +Mammary gland morphogenesis 0.5003876183023157 0.6069428812588277 0.5438888190635023 1.0 0.8275631693188192 4 Q15648 1 +Histone lysine demethylation 0.473929252997298 0.6063247670469567 0.5442991153662147 1.0 0.8279944118601206 7 Q8IUF8 1 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.4558480973033901 0.6059024837512758 0.5445795100469735 1.0 0.8282278915326379 3 P61254 1 +Iron ion transport 0.452542022633234 0.605522650971598 0.5448317790243475 1.0 0.8282597079277637 9 O15173 1 +Innate immune response 0.2681722254357043 0.6022149312982236 0.5470310779310603 1.0 0.830601399389972 139 Q7Z739,Q09472,Q15648,P34897,Q15233,Q9BY67,Q3LXA3,Q16512,P61160,O15111,P26583,Q12846,Q8WXF1,Q15366,Q9BQ95,P14174,P78362,Q8TDB6,P08670,Q9H078,Q06481,Q14166,P09429,P51159,Q9NUD5,Q9NVI7 26 +Signal transduction by p53 class mediator 0.2911841544355878 0.600267551184295 0.5483279405392858 1.0 0.831774011213034 51 Q09472,P14174,P62841,Q9NYV6,P42345,O14757,Q9NZM5,P61254,P62081,O14744,Q96RU2,Q01664,Q96JB5,O75844,Q92993 15 +Nucleotide transport 0.4127806149410068 0.6000984389291718 0.5484406328914626 1.0 0.831774011213034 13 Q9H2D1,Q9BSK2 2 +Ncrna export from nucleus 0.4722203276556801 0.5991531080069332 0.5490707893515276 1.0 0.832170377857622 7 Q09161 1 +Negative regulation of neural precursor cell proliferation 0.4842855716885774 0.5991035543446676 0.5491038316144679 1.0 0.832170377857622 6 P35221,Q06481,Q8IXJ6 3 +Regulation of protein localization to cell cortex 0.4913735554095574 0.5989412737333027 0.5492120468024484 1.0 0.832170377857622 5 Q14980,P63096,P53350 3 +Negative regulation of immune effector process 0.4509078844587555 0.5981859126589932 0.5497158901107946 1.0 0.832375664776159 9 P09601 1 +Cellular ion homeostasis 0.2778779010248412 0.598163092210106 0.5497311154226223 1.0 0.832375664776159 88 P12277,Q8N511,Q96PU5,P06576,P09429,P09601,Q93050,P50897,Q9HD20,Q92544,P16615,P51572,P17252,Q9Y487,P27695,Q9UJZ1,Q9UM00 17 +Negative regulation of cytoskeleton organization 0.2908194780384986 0.5965745461638126 0.5507914696067151 1.0 0.8330162527586148 51 P04350,P52907,Q13177,Q13485,P47755,Q9NWH9,P29372,Q01082,Q92974,Q9NYL9,P35241,P16949,O75122,Q9BR76,O94813,O15344,Q9UBN7,Q9UEY8,P60983,Q13813 20 +Cell cycle phase transition 0.2505284145093182 0.5947026366928151 0.5520422590476661 1.0 0.8341699990924292 170 Q96BK5,Q9UJX5,Q93034,Q9NZM5,Q8WUX9,Q6UVJ0,P49959,P50570,Q7Z7L1,Q99623,P08183,Q96HY6,Q12959,Q96EA4,Q00534,P15927,O95067,P61254,Q6NUQ1,Q14674,Q16763,Q9UJX4,P51530,Q9H1A4,Q96JB5,P27695,P24941,P12270,O14757,P16104,Q99459,O95905,Q5JVF3,P19447,Q06481,P61289,Q9UJX2,Q68E01,P35241,P18074,Q92547,O75122,P54132,P62753,Q9UNS1,Q96RU2,Q01664,P51608,O60885 49 +Regulation of intrinsic apoptotic signaling pathway 0.2905584962748525 0.593934128621248 0.5525561712957949 1.0 0.8345799938767293 51 P45880,P14174,Q9P0J0,Q9NYV6,Q15233,O60313,P61254,P62081,P51572,O00429,Q9NYF8 11 +Poly a plus mrna export from nucleus 0.4313481260361487 0.5932230273439231 0.553031903801156 1.0 0.834663784506555 11 Q86U42,Q5JVF3,O60318 3 +Taxis 0.2808406404653759 0.5917010253773187 0.5540508098085408 1.0 0.8350428602333804 70 Q09472,P14174,P26583,Q9BR76,O00264,P09429,Q12846,P42892,O00429,P35613,P63000 11 +Negative regulation of smooth muscle cell proliferation 0.4701362510614181 0.5904390220390648 0.554896355667746 1.0 0.8358870901238886 7 Q14344,Q15637,Q53EL6,P09601 4 +Integrin activation 0.4515729972066547 0.5880552543863068 0.5564952057643058 1.0 0.8373533174874586 3 O94887 1 +Negative regulation of mitotic cell cycle phase transition 0.2868670471911009 0.5877237088687318 0.556717759088273 1.0 0.8373533174874586 54 Q12959,Q96BK5,Q92547,P24941,P15927,P12270,O14757,Q9NZM5,P61254,Q6NUQ1,P54132,P49959,Q5JVF3,Q7Z7L1,Q96JB5,Q68E01,Q96EA4 17 +Epigenetic maintenance of chromatin in transcription competent conformation 0.4813506476249193 0.5872717946243843 0.5570211809968657 1.0 0.837392358255136 6 Q09472 1 +Morphogenesis of a branching structure 0.3521793321414303 0.5854396238548684 0.5582521522856063 1.0 0.8380003708884902 22 Q15648,Q13043,Q13485,Q14344,Q9UNS1,P62136,Q16512,Q99623,Q9NWH9,Q12959 10 +Regulation of protein localization to cell surface 0.4297045822117721 0.585387819901124 0.5582869767628242 1.0 0.8380003708884902 11 Q96PU5,Q92544 2 +Positive regulation of dna replication 0.3853698278774047 0.5848888388494015 0.5586224638041857 1.0 0.8380003708884902 16 P51530,Q04837,P24941 3 +Pallium development 0.311426737272421 0.5845681532956908 0.558838126586992 1.0 0.8380003708884902 36 P50542,Q00534,P35240,Q9HCS7,Q13144,Q96N66 6 +Regulation of lipid metabolic process 0.289512355086193 0.5833712379202717 0.5596434156610419 1.0 0.8388487832889463 51 Q96G23,P07602,Q8NCG7,Q96N66,Q8WTV0 5 +Cardiac muscle cell action potential involved in contraction 0.4386094233941365 0.58334513035864 0.5596609871958431 1.0 0.8388487832889463 10 Q96PU5 1 +Regulation of cysteine type endopeptidase activity 0.2955136878647014 0.5829548649583736 0.559923684833596 1.0 0.8388572009237941 47 Q9P0J0,P09429,Q5JVF3,Q15392,Q96A26 5 +Response to axon injury 0.3990945975026789 0.582688896214469 0.5601027494580086 1.0 0.8389328765120414 14 P00374 1 +Translesion synthesis 0.4473140588253222 0.5821347943568383 0.5604758900939069 1.0 0.8389690504997789 9 P28340,Q9UBZ9 2 +Axo dendritic transport 0.3244663055061039 0.581632127438715 0.5608144977970784 1.0 0.8392284826011771 29 Q9Y496,P33176,Q14254,O60313,Q00839,Q03001,Q9UBN7,P23246,P27695 9 +Regulation of leukocyte differentiation 0.317970719105376 0.580514422119185 0.5615677639170047 1.0 0.8395740298378847 32 Q00534,O43290,P09429,Q5JVF3,P17252 5 +Positive regulation of cell growth 0.3013418454803933 0.580360330200808 0.5616716509585431 1.0 0.8395740298378847 41 Q96PU5,Q6PJG6,Q9BSK2,Q09161 4 +Glial cell development 0.3472458936994635 0.5798133667958335 0.5620404825551251 1.0 0.8397230471254935 23 P18074,P08670,Q00534 3 +Regulation of autophagy of mitochondrion 0.3841853246470629 0.5782937386841264 0.5630658209674857 1.0 0.8401407174793774 16 O00429,P21796 2 +Regulation of osteoblast differentiation 0.4280666849911905 0.5776064888576756 0.5635298250458489 1.0 0.84020919311154 11 Q00534 1 +Positive regulation of brown fat cell differentiation 0.4482322737901454 0.5742239377072073 0.5658162726883873 1.0 0.8418698882845612 3 Q00839 1 +Regulation of organ growth 0.4273119496229776 0.5740300986950587 0.5659474337059422 1.0 0.8418698882845612 11 Q13043 1 +Protein localization to phagophore assembly site 0.4661830039218501 0.5740085976518541 0.5659619832694893 1.0 0.8418698882845612 7 Q9Y2L5 1 +Mrna transcription 0.4454244516184184 0.5737428494785157 0.5661418275046304 1.0 0.8418698882845612 9 Q09161 1 +Negative regulation of defense response to virus 0.4659620635593933 0.5730942478719647 0.5665808817145359 1.0 0.8422566820202874 7 Q15366,Q3LXA3 2 +Muscle system process 0.2795505645374082 0.5721131409397259 0.5672453270309266 1.0 0.8424767874838022 69 Q05682,Q86U42,Q86TU7,P46939,P25490,P06753,Q96PU5,P17252,Q13555,P09601,P16615,Q9Y4J8,Q99996,Q9Y5P4,P67936,Q12959 16 +Regulation of cytoplasmic transport 0.3898481094510093 0.5703405231963611 0.5684467611198725 1.0 0.843377434762623 15 P35241,P26038,P15311 3 +Regulation of mitotic cell cycle phase transition 0.2778344906464088 0.5702651026840418 0.5684979061478361 1.0 0.843377434762623 101 Q96BK5,Q9UJX5,Q9NZM5,Q6UVJ0,P49959,Q7Z7L1,Q99623,Q12959,Q96EA4,P15927,P61254,Q6NUQ1,Q14674,Q9UJX4,Q96JB5,P27695,P24941,P12270,O14757,O95905,Q5JVF3,P19447,Q06481,P61289,Q9UJX2,Q68E01,P35241,P18074,Q92547,P54132,Q01664,P51608,O60885 33 +Neuroblast proliferation 0.4167457175323806 0.5694226951808496 0.5690693187020432 1.0 0.8435406547901956 12 Q8NCG7,Q92974,Q96N67 3 +Protein localization to extracellular region 0.2824345053942139 0.5673985300269349 0.5704434483747596 1.0 0.8448367562998979 57 Q96KC8,P00367,P15311,Q32P28,Q16850,O00429,P53985 7 +Regulation of cell projection organization 0.2744736724881553 0.5672898795892303 0.5705172517642736 1.0 0.8448367562998979 122 Q16181,Q09472,Q32P28,Q13555,P50570,Q14651,Q9UQB8,Q16512,Q14108,P15311,P61160,P27695,Q7KZI7,Q66K14,Q96PU5,P08670,Q9HCE1,P51116,Q4KMP7,P35241,Q96G23,Q9BR76,P29373,P63000 24 +Substantia nigra development 0.3746233481758144 0.5655826115170681 0.5716775511106842 1.0 0.84636290801913 17 P18859,P14854,P00367 3 +Positive regulation of protein localization to cell cortex 0.4890947116821107 0.5638038226645601 0.5728876499668936 1.0 0.8476542077529093 4 Q14980,O43491,P63096 3 +Positive regulation of glial cell differentiation 0.4753152125163387 0.5631576601150668 0.5733275310651933 1.0 0.8478439763724114 6 P42345 1 +Positive regulation of apoptotic signaling pathway 0.3156621732576629 0.5622595954819668 0.5739391626800106 1.0 0.8480659868383942 32 Q13177,Q13043,P61254,P62081,P51572,O00429,P23246,P62136,O75569,Q9NYF8 10 +Hippocampus development 0.3881065749046804 0.5609779528603545 0.5748125670190933 1.0 0.8483243434907836 15 Q9H0D6,Q00534,P35240,P18887,O14949,Q13144,Q02218 7 +Spermidine metabolic process 0.4449267700060223 0.5606417692847347 0.5750417709558491 1.0 0.8483243434907836 3 P19623 1 +Negative regulation of signal transduction by p53 class mediator 0.4629401744476497 0.560631043436783 0.5750490843580442 1.0 0.8483243434907836 7 P14174,Q9NYV6 2 +Nucleoside triphosphate biosynthetic process 0.310032065801911 0.5605823737730259 0.5750822702426028 1.0 0.8483243434907836 35 Q05682,P18859,P04818,P06576,O75964,P56134,P25705,P55263,Q9UJZ1 9 +Chromatin disassembly 0.3945012686962221 0.5586181908668483 0.5764223225304355 1.0 0.8493411778807003 14 Q9BQ67,Q969G3,P17096 3 +Lysosomal transport 0.2928739115202538 0.5577174823621719 0.5770373178382513 1.0 0.8500554257815864 47 Q14108,P07602,Q8TDB6,Q9P2R3 4 +Granulocyte migration 0.3731710272810576 0.5573262078371054 0.5773045727057033 1.0 0.8502571973544166 17 O00429,P35613 2 +Protein localization to cytoskeleton 0.3512977201238599 0.5558091417101514 0.578341335419182 1.0 0.8512949100287891 21 Q14789,Q13561,Q00839,O15344 4 +Sterol homeostasis 0.4234140130451447 0.55565426422516 0.5784472278916728 1.0 0.8512949100287891 11 Q8WTV0 1 +Epidermis development 0.286695243518023 0.5551015237504988 0.5788252206066704 1.0 0.8513838400567654 51 P18074,P67809,Q13464,O60568,Q15648,Q14254,Q13043,P29373,Q14651,Q8NEY8,Q99816,O75844,P16615,P51648 14 +Negative regulation of response to cytokine stimulus 0.4232261075158377 0.5547725299729335 0.5790502587536026 1.0 0.8514830979328549 11 Q7Z739,Q01804,O94813,Q9UJ41,Q9Y3Z3,Q14166 6 +Organonitrogen compound biosynthetic process 0.2424667567074789 0.5543543027348894 0.5793363936219813 1.0 0.8517119407021965 585 Q05682,P43490,O15269,P34897,P23381,P83436,Q96C36,Q567V2,O75964,P04062,P00374,Q15024,Q9ULC4,P42345,P57772,P61254,Q16540,P46778,Q96PU8,Q92643,Q13126,Q8NFF5,P36551,P53582,O60506,Q09161,P08670,P84098,Q13310,Q8WVC6,Q4G176,Q96A35,Q96S52,P62899,O95900,Q9Y673,P53007,Q969T7,Q96G23,Q7LGA3,O00264,P50897,P62753,P15880,P19623,Q7Z7H8,P62136,P46776,Q99805,Q9Y3D3,Q8TB61,Q7Z739,P67809,P62841,Q9H2M9,Q9NR50,Q6IAN0,Q9Y5P6,P25705,P33908,P12532,P24539,P46199,Q9HA77,P50914,P55263,Q10713,Q96KC8,P00367,P41567,Q15650,P62917,P51116,Q9BW92,P46782,P18859,P04818,P61513,P55010,P31483,Q8N5C6,O60568,Q9BPZ3,Q96EY7,Q6ZXV5,P35790,O75879,Q9BQG2,Q9BTE6,A1L0T0,Q96GX9,Q8WU90,Q9H6U8,P25398,Q99873,Q9HCE1,P29692,Q08379,O60502,Q9NPI6,P27635,P20042,Q10472,Q9Y285,Q2TAA5,Q9NRG1,Q14103,P62081,Q00839,Q13144,P12277,P06576,P08865,P12270,P48651,P49458,P56134,Q9UJZ1,O60294,Q02543,Q06136,Q53GQ0,Q92552,Q9H074,Q9Y295 125 +Positive regulation of epithelial cell proliferation 0.3389068804797756 0.5528425961242073 0.5803711977681827 1.0 0.8529257662984241 24 P26583,P09429,P09601,Q9H2J4 4 +Regulation of microtubule based process 0.2736748211124871 0.5526017971174062 0.5805361111407361 1.0 0.8529257662984241 77 Q8WUX9,Q6UVJ0,Q16512,P04350,Q99996,P57076,P54646,Q00839,Q9NWH9,P27695,Q7KZI7,P12270,Q92974,Q9NS87,P16949,O75122,P30622,Q9Y295,O15344,P63000 20 +Basement membrane organization 0.4726423521004534 0.5525754884009448 0.5805541302325468 1.0 0.8529257662984241 6 O75122,O60568 2 +Cell morphogenesis 0.2393265869617331 0.5521837525895911 0.5808224648253184 1.0 0.8531279328044177 187 Q96AX1,Q16181,P35580,Q09472,Q96N67,Q15648,O60568,Q9Y2A7,P50570,Q14651,P42892,Q9UQB8,Q16512,P35613,O75844,P12814,Q12959,Q14185,Q9Y263,Q13177,Q13043,P15311,P61160,Q96F07,Q9Y5P4,Q9NWH9,Q9NZM3,Q7KZI7,O75695,Q13464,A0MZ66,Q96PU5,O60749,Q92974,Q9HCE1,Q06481,P35579,P35241,P16949,Q9Y2J2,Q9H2U1,Q9BR76,O00264,P29373,Q9UNF0,P26038,P63000 47 +Positive regulation of mitochondrial membrane potential 0.4855267498512208 0.5503807954026955 0.5820582180450882 1.0 0.8537848357405255 4 Q9UJZ1,Q8IWA4 2 +Regulation of cell morphogenesis 0.276077282110773 0.5465474707562411 0.5846896659981491 1.0 0.8564948956911157 72 P35241,Q16181,P35580,Q9Y263,P15311,P61160,Q96PU5,Q9BR76,P50570,Q9HCE1,Q9UQB8,P26038,P63000,Q7KZI7,Q12959 15 +Protein exit from endoplasmic reticulum 0.3562957971675722 0.5463491096926939 0.5848259845858115 1.0 0.8565023284127032 19 Q8TCT9,P49257,Q8IWJ2,P51572,Q92544,P55735,Q8TAT6 7 +Regulation of metal ion transport 0.2797819268212422 0.5433479852788186 0.5868902314324398 1.0 0.8577929787968873 59 P46939,P17252,P35754,Q96PU5,Q9UKS6,Q13555,P50570,P21796,Q99996,P27695,Q12959 11 +Regulation of ire1 mediated unfolded protein response 0.476011992596622 0.539307787332929 0.5896744964013552 1.0 0.8604729851555536 5 Q96HY6 1 +Positive regulation of protein polyubiquitination 0.4825216611891334 0.5391567801708587 0.589778679528163 1.0 0.8604729851555536 4 O00571,O75150,P98170 3 +Regulation of mitotic recombination 0.4818970448292212 0.5368333916651246 0.5913827040771926 1.0 0.8608885850563817 4 P18074,P49959 2 +Pyrimidine nucleoside triphosphate metabolic process 0.4001088002486283 0.5360489628862782 0.5919247115795863 1.0 0.8614125342287667 13 Q9H773 1 +Telomere capping 0.390125502214116 0.5359304452676912 0.5920066221293316 1.0 0.8614125342287667 14 Q14103,P18887,P27361,P49959,Q9UBB9 5 +Regulation of erad pathway 0.468263700572871 0.5353743581229816 0.5923910176051272 1.0 0.8617797104081721 6 P51572 1 +Negative regulation of mapk cascade 0.3105576347520374 0.5346810905861029 0.5928703993685895 1.0 0.8619006964311463 33 P15311,P04062,Q12959 3 +Negative regulation of protein binding 0.3316150604443113 0.5339064976757215 0.5934062263508593 1.0 0.86246418596546 25 Q08379,Q6IAN0,P27361,O75381,P62136,P30533,P16615,Q9UBB9 8 +Negative regulation of cell activation 0.3476659270007388 0.5330893092866618 0.5939717591395155 1.0 0.8624767393076047 21 P09429,P09601 2 +Regulation of non motile cilium assembly 0.4673863974488931 0.5319485622860342 0.5947616217270721 1.0 0.8624767393076047 6 P50570,P27695 2 +Protein insertion into er membrane 0.408939897565009 0.5315870071899257 0.5950120655397546 1.0 0.8624767393076047 12 O43681,Q15006,Q9P0I2,Q7L5D6,Q96A33 5 +Positive regulation of microtubule polymerization or depolymerization 0.3611076645321623 0.5303645630205688 0.5958591907499033 1.0 0.8631691628932008 18 P30622,Q9Y295,Q16512,P63000,Q99996,Q9NWH9 6 +Negative regulation of small gtpase mediated signal transduction 0.3888449757570656 0.5293380112047774 0.5965709915775679 1.0 0.863639284015931 14 Q9UJ41,P16949,Q9H3F6,O95630 4 +Corpus callosum development 0.4798326859874667 0.5291783908731656 0.5966817054993165 1.0 0.863639284015931 4 Q99622,Q96P11,Q00535 3 +Regulation of stem cell differentiation 0.3502205731977924 0.5282699647383688 0.5973119750426483 1.0 0.8639515575566751 20 Q96PZ0,Q00534,Q9Y6C9,Q13610,Q00839,Q9Y4C1 6 +Secretion 0.2621119917405916 0.5282664163244727 0.5973144375392663 1.0 0.8639515575566751 142 P35580,Q15648,Q32P28,Q13555,Q16512,Q7Z392,Q15019,O14795,P15311,Q9H7Z7,P09601,Q16850,Q12846,P27695,Q4J6C6,P14174,Q96KC8,P00367,O00429,Q9UPT5,O43760,O75122,Q9UNH7,P51159,P50897,Q9UJ41,Q13505,P53985,P16615 29 +Telencephalon development 0.2995676580558355 0.5282497657786133 0.5973259925981793 1.0 0.8639515575566751 39 P50542,Q00534,P35240,Q9HCS7,Q13144,Q96N66 6 +Sulfur compound biosynthetic process 0.2974846408013938 0.5272552960523097 0.5980163137366488 1.0 0.8645627890684715 40 Q4G176,P53007,Q13126 3 +Cellular response to increased oxygen levels 0.4544468082972905 0.5260460096685287 0.5988562397825641 1.0 0.8650145685748148 7 Q9Y487 1 +Regulation of cellular amide metabolic process 0.2387169866457058 0.5252027242950326 0.5994422712931093 1.0 0.865286499106134 191 Q7Z739,P67809,P34897,Q9BPZ3,Q96EY7,Q567V2,P00374,P46199,Q15024,Q14103,P42345,P57772,Q00839,Q96PU8,Q13144,P27695,Q10713,Q96KC8,P53582,Q09161,P41567,P08670,P12270,P49458,Q9HCE1,P51116,O95900,P04818,Q969T7,Q9NPI6,P55010,Q92552,P27635,Q9H074,P31483 35 +Regulation of sulfur metabolic process 0.393550313526422 0.5226156653163415 0.60124173687861 1.0 0.8673084825087994 2 O75027 1 +Response to insulin 0.2759474374415067 0.5212837123836639 0.602169145593817 1.0 0.8684543301978451 66 P43490,Q9UQB8 2 +Mitotic g1 s transition checkpoint signaling 0.4332660524318211 0.5205859122486439 0.6026552652576529 1.0 0.8687714294392408 9 P15927,P24941 2 +Positive regulation of potassium ion transport 0.4235593283182944 0.5152942770360722 0.6063473975007074 1.0 0.8725519550362991 10 Q99996,Q12959 2 +Metal ion export 0.431391965919914 0.5125294593778209 0.608280508061833 1.0 0.874562369599366 9 Q4KMQ2,Q12959 2 +Response to peptide 0.2733290333676015 0.5108739530701266 0.609439320978137 1.0 0.8760354644720975 101 P43490,P08670,Q9UQB8,Q9BSK2,P35613,Q06481,P27695 7 +Amyloid fibril formation 0.4503112126572016 0.5094560043201827 0.6104326291861717 1.0 0.8762059723774842 7 P61758,Q9NQP4 2 +Multicellular organism reproduction 0.2704236838618044 0.5094205923558269 0.6104574453373057 1.0 0.8762059723774842 122 Q16181,Q14997,Q9BY67,Q9BPZ3,P51572,P50570,P54619,P35613,Q15019,P26583,O95067,Q14141,Q96PU8,Q9Y2W6,P25490,O75718,P16104,P17252,Q9UHB7,Q9P0K7,P62753,P20042,Q9Y4C1,Q9BTX1 24 +Dna dealkylation 0.4383802031812008 0.5079274673909395 0.6115042110740849 1.0 0.8762059723774842 8 P27695,Q01804 2 +Hair cell differentiation 0.4126996418220844 0.5060160760613782 0.6128453641753526 1.0 0.8772601111226916 11 P18074,Q14651 2 +Positive regulation of cell population proliferation 0.2669689004886783 0.505604235191841 0.6131345078535841 1.0 0.8774815347044934 130 P43490,O76071,O95630,Q96HY6,Q12959,Q9ULC4,Q00534,P26583,P09601,Q9H2J4,P14174,P78362,P24941,Q99873,Q9BSK2,Q969Z0,P09429,P62753,P55209 19 +Cell death in response to oxidative stress 0.322731742564713 0.5050551365812672 0.6135201105811185 1.0 0.8778408773629423 26 Q15233,P04062 2 +Lysosomal lumen acidification 0.4725588371449217 0.5025058305416487 0.6153117520803184 1.0 0.8794630026102717 4 P50897 1 +Regulation of microtubule cytoskeleton organization 0.275684931490943 0.5024164744937077 0.6153745928442276 1.0 0.8794630026102717 60 P16949,O75122,P30622,P12270,P54646,Q8WUX9,Q9Y295,Q00839,O15344,Q92974,P04350,Q16512,P63000,Q99996,Q9NWH9,Q7KZI7,Q9NS87 17 +Negative regulation of amyloid fibril formation 0.4658328803267261 0.5009073060860869 0.6164363604011902 1.0 0.8798914453145598 5 P61758,Q9NQP4 2 +Regulation of amyloid fibril formation 0.4658328803267261 0.5009073060860869 0.6164363604011902 1.0 0.8798914453145598 5 P61758,Q9NQP4 2 +Plasma membrane organization 0.3164571904010032 0.4990977958381898 0.6177104902791029 1.0 0.8807438596745636 28 Q9Y2J2,Q01082,Q9UKS6,Q8WUX9,P50570,Q4KMQ2,Q12846,Q9UNF0,Q9UQB8,P16615 10 +Lytic vacuole organization 0.3348535183005317 0.4989320331464323 0.6178272663178781 1.0 0.8807438596745636 23 Q14108,P04062 2 +Regulation of blood pressure 0.3625099222829428 0.4976533682527965 0.618728381014785 1.0 0.8815674881280289 17 P42785,P09601 2 +Negative regulation of striated muscle cell differentiation 0.4473070776921827 0.4975130109298706 0.6188273301180078 1.0 0.8815674881280289 7 P67809 1 +Protein localization to microtubule organizing center 0.4016637770645671 0.4969812313301874 0.6192022867630034 1.0 0.8817181155172071 12 Q13561 1 +Liposaccharide metabolic process 0.4005871610512415 0.4919186209751643 0.6227768739828694 1.0 0.8847526374927033 12 P04062 1 +Histone phosphorylation 0.3296797581113352 0.4916143500813215 0.6229919969724358 1.0 0.8847526374927033 24 P24941,Q13043,O14757,P54646,P27361,Q16512,P17252 7 +Protein localization to lysosome 0.3814236248415618 0.4915741167424993 0.6230204448108139 1.0 0.8847526374927033 14 Q14108 1 +Negative regulation of locomotion 0.2869480561347077 0.4911628754024117 0.6233112540122216 1.0 0.8847526374927033 46 P14174,Q96G23,P35240,Q9BR76,P09429,P09601,Q9UJ41,P27695 8 +Receptor clustering 0.3907839244432289 0.4901832034593361 0.6240042653537101 1.0 0.8852721381952853 13 P49354 1 +Aminoacyl trna metabolism involved in translational fidelity 0.4176943582364705 0.4894545451304288 0.6245199277616802 1.0 0.8854706764121142 10 Q9BW92 1 +Epithelial cell proliferation 0.2887462863537242 0.489228326380992 0.6246800573756119 1.0 0.8854706764121142 44 Q00534,P26583,P09429,P09601,Q9H2J4,Q8WTV0,Q12959 7 +Alpha beta t cell differentiation 0.4089885823378325 0.4891433397546683 0.6247402199917018 1.0 0.8854706764121142 11 P09429 1 +Regulation of striated muscle contraction 0.3538536975650195 0.4888639140294826 0.6249380450085911 1.0 0.8854706764121142 18 Q99996,P16615,Q12959 3 +Positive regulation of intracellular transport 0.2727284000757053 0.4880907157726435 0.6254855869574403 1.0 0.8859006134972637 67 Q9Y282,P35241,Q9P2W9,O14737,P15311,P12270,P51572,Q92544,Q9C0E2,P17252,P26038,Q9UIS9 12 +Regulation of t cell proliferation 0.3607594042675313 0.4880234152468996 0.6255332557455395 1.0 0.8859006134972637 17 P09429 1 +Immune system development 0.2398154043987876 0.4843692620430761 0.6281238289545072 1.0 0.8885210459323769 176 Q96AX1,Q09472,P24390,O95376,Q15648,Q6IAN0,P04062,Q16512,Q96FZ2,O75844,Q6FI81,Q00534,Q13043,P26583,P13051,P42345,O95067,O60318,O00625,Q96JB5,Q9Y4E6,P25490,O94874,P48426,O43290,Q13310,Q99873,Q8WYA6,Q5JVF3,Q96EY1,P17252,Q9GZZ9,P18074,O96005,O94887,Q86XI2,P09429,P62753,P27361,Q6NYC1 40 +Ion homeostasis 0.2711375106398551 0.4842612889296858 0.6282004452853183 1.0 0.8885210459323769 110 P30519,Q93050,P51572,Q9Y487,P09601,Q9HD20,P27695,P12277,Q96PU5,P06576,Q8NE01,P17252,Q9UJZ1,Q9UM00,Q8N511,P09429,P50897,Q92544,P16615 19 +Long chain fatty acid transport 0.3895104963338715 0.4840113707903304 0.6283777993454136 1.0 0.8885793106236552 13 P23786,P14174 2 +Hypothalamus development 0.4611462583371882 0.4835549010051467 0.6287017878674246 1.0 0.8888448586704534 5 P27695 1 +Metal ion homeostasis 0.2661726400568308 0.4823544680584731 0.6295541602902066 1.0 0.8895449172855748 81 P30519,Q8N511,Q96PU5,P09429,P09601,Q9HD20,P16615,P51572,Q8NE01,P17252,Q9Y487,P27695,Q9UJZ1,Q9UM00 14 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.4665957238177657 0.481004371165432 0.6305133920356054 1.0 0.8900709279547154 4 Q09472,Q96HY6 2 +Regulation of programmed necrotic cell death 0.4153454835911865 0.4792221618407488 0.6317805897767035 1.0 0.8904832361366027 10 Q92974,P12235 2 +Cell cycle g2 m phase transition 0.2762219653632771 0.4791126630423871 0.6318584816416302 1.0 0.8904832361366027 54 Q96BK5,Q92547,P24941,P51608,O95067,Q9NZM5,Q6NUQ1,O14757,P54132,P50570,Q96JB5,P08183,Q68E01,O60885 14 +Positive regulation of neutrophil migration 0.4598657364973151 0.4788514102269779 0.632044340085474 1.0 0.8904832361366027 5 O00429 1 +Positive regulation of granulocyte chemotaxis 0.4598657364973151 0.4788514102269779 0.632044340085474 1.0 0.8904832361366027 5 O00429 1 +Neural nucleus development 0.3445500246241185 0.476956092973699 0.6333933875673887 1.0 0.8914223090931159 19 P18859,P14854,P00367 3 +Nuclear pore organization 0.3870807247518314 0.4722995396337807 0.6367129989188132 1.0 0.8941233709868016 13 P12270,Q9BTX1,Q96EE3 3 +Regulation of translational fidelity 0.3646092085657818 0.472101695154384 0.6368542025722641 1.0 0.8941233709868016 16 Q9BW92,P46782 2 +Response to purine containing compound 0.364430196279547 0.4711575013395008 0.6375282650725103 1.0 0.8945408423700714 16 P15311,Q99996,P35613 3 +Negative regulation of cell cycle g2 m phase transition 0.3264252231063054 0.4704286854241514 0.6380487738467251 1.0 0.8945877533967912 24 Q96BK5,Q92547,O14757,Q9NZM5,Q6NUQ1,P54132,Q96JB5,Q68E01 8 +Forebrain cell migration 0.4045337048291892 0.4691220187762146 0.6389824211814488 1.0 0.8946223947582381 11 Q96N66,Q8WXH0,P50542,Q02218 4 +Mitotic g2 dna damage checkpoint signaling 0.3702232195257821 0.4672458829783347 0.6403239698397729 1.0 0.8955865065451104 15 Q92547,O14757,P54132,Q9NZM5,Q6NUQ1,Q96JB5 6 +Response to peptide hormone 0.2682838302251765 0.4663633496390668 0.6409554407734954 1.0 0.8958606205626044 91 P43490,Q9UQB8,Q9BSK2,P35613,P27695 5 +Immune response regulating signaling pathway 0.2710211499070326 0.4630346559664247 0.6433395263394113 1.0 0.8978686374873819 63 Q09472,Q9NR50,Q9NZM5,Q3LXA3,Q16512,Q99623,P46379,Q01804,Q13177,Q14254,P15311,Q13144,Q8TAT6,Q9H078,Q06481,Q9UJZ1,P09429,Q9UJ41,Q9NUD5 19 +Protein autoprocessing 0.4554692169754853 0.4628293575070989 0.6434866863414426 1.0 0.8978820002275506 5 Q9UG56,P09874,Q9Y4W6,P17655 4 +Cell junction maintenance 0.4195034554589926 0.462356997486288 0.6438253318513947 1.0 0.8980216302633293 9 Q8IUD2 1 +Establishment or maintenance of bipolar cell polarity 0.3419572355954783 0.4619656296596712 0.6441059682715959 1.0 0.8980216302633293 19 P15311,P26038,Q12959 3 +Regulation of dna templated transcription in response to stress 0.3754438239485788 0.4617302310300883 0.6442747889814446 1.0 0.8980216302633293 14 Q9NWT6,O14757,P09601 3 +Regulation of lipid catabolic process 0.426447918061574 0.4593044198993254 0.6460155742340272 1.0 0.8992955711286821 8 Q8WTV0 1 +Cellular response to ph 0.3783218871304843 0.4576378990904968 0.6472126105426668 1.0 0.900048968133655 2 Q9UHD1 1 +Negative regulation of response to external stimulus 0.2809338553141869 0.4574815894101323 0.6473249322742634 1.0 0.900048968133655 48 Q7Z739,P14174,Q96G23,P80303,Q9BR76,Q3LXA3,Q9UJ41,P04062,Q8TAT6,Q15366,Q14166 11 +Aortic valve morphogenesis 0.4595805295378872 0.4561548190328591 0.6482786522804811 1.0 0.900908535941742 4 Q13464,O94813 2 +Roundabout signaling pathway 0.3774260973424877 0.4539209127925981 0.6498857509474247 1.0 0.9023732788687124 2 O94813 1 +Cleavage furrow formation 0.3774260973424849 0.4539209127925868 0.649885750947433 1.0 0.9023732788687124 2 Q9Y5X1 1 +Embryonic heart tube development 0.4528470101562646 0.4533690771913097 0.6502829994058144 1.0 0.902607218433438 5 P42892 1 +Double strand break repair via break induced replication 0.4172176126866226 0.4529055368046513 0.6506167638362568 1.0 0.902607218433438 9 Q14566,Q9BRT9,P33992,P25205 4 +Regulation of dendrite morphogenesis 0.360849019793904 0.4523818987311115 0.6509938848838195 1.0 0.902607218433438 16 Q9UQB8 1 +Midbrain development 0.3372766974197829 0.4510514709555627 0.6519524527956981 1.0 0.9033699782394438 20 P18859,P12277,P00367,P14854,Q8IXJ6,P63167,P24539 7 +Rna phosphodiester bond hydrolysis endonucleolytic 0.3010656544640944 0.4498444976632723 0.6528225700687642 1.0 0.9036694760580098 32 Q9BQG2,P27695,Q96DE0,Q9Y2C4 4 +Tissue migration 0.2707890289665991 0.4490163286906401 0.6534198775251814 1.0 0.9038071264576923 59 P25705,Q16512,Q8WTV0,Q4VCS5,Q14185,P42345,P09601,Q9NWH9,Q13464,P19174,P06576,P42785,P35579,P17252,P67870,O75122,Q9BR76,P09429,Q9UBN7,P51608,P63000 21 +Myofibroblast differentiation 0.4160623447407169 0.4469606042844208 0.6549035048264396 1.0 0.9049121898152328 3 Q53EL6 1 +Regulation of neural precursor cell proliferation 0.3658544519961029 0.4450891857721706 0.6562553036034495 1.0 0.9056352366554272 15 Q06481,P55209 2 +Regulation of protein localization to plasma membrane 0.3137675635934838 0.4438886518114187 0.6571230895716178 1.0 0.9059250911917972 26 P15311,Q14651,O00264,Q12959 4 +Regulation of circadian rhythm 0.3057295416152787 0.4436967948349003 0.657261813084459 1.0 0.9059250911917972 29 Q15233,Q14103,P42345,P54646,Q8WXF1,P23246,P62136 7 +Cellular response to heat 0.3086151403825275 0.4435521380218301 0.6573664160020145 1.0 0.9059250911917972 28 Q09472,P42345,P12270,P09601,Q9H078,P17252 6 +Regulation of cilium assembly 0.3386061970663288 0.4427821663117691 0.657923303833059 1.0 0.9059250911917972 19 P50570,P27695,Q4KMP7,Q66K14 4 +Cerebral cortex cell migration 0.4067949405101076 0.4425685456568637 0.6580778402399421 1.0 0.9059250911917972 10 Q96N66 1 +Negative regulation of protein localization to nucleus 0.4146983513456985 0.4425659796304443 0.658079696631013 1.0 0.9059250911917972 9 Q6GQQ9,P61960 2 +Alpha beta t cell activation 0.3588673949061215 0.4420874315545772 0.6584259389453233 1.0 0.9059250911917972 16 P09429,Q9UJZ1 2 +Golgi ribbon formation 0.4495295787248099 0.4415060236697002 0.6588467016431596 1.0 0.9059250911917972 5 Q08379,Q8IWJ2 2 +Negative regulation of secretion 0.3453702413342071 0.4414810401135711 0.6588647845701261 1.0 0.9059250911917972 18 Q16850,P09601 2 +Multicellular organism growth 0.3109328389881019 0.4411475313352148 0.6591061950404711 1.0 0.9059250911917972 27 P18074,Q09472,P50542,P15311,P42345,Q14651 6 +Protein localization to cell junction 0.3292502163243465 0.4410220578183845 0.6591970282955442 1.0 0.9059250911917972 22 Q9UQB8 1 +Regulation of bone mineralization 0.4432201052273844 0.440550049735986 0.6595387711533289 1.0 0.9059250911917972 6 Q4KMQ2,Q9NUQ3,O75844 3 +Spindle assembly 0.2732507071338916 0.4403176788569923 0.6597070382137677 1.0 0.9059250911917972 53 Q9UQE7,O43663,Q08379,O75122,P12270,O95067,Q8WUX9,Q9Y295,Q00839,Q9BSJ2,O00139,Q9BW19,Q9Y2S7 13 +Regulation of glycolytic process 0.4061325830759458 0.4397697183141638 0.6601039018321535 1.0 0.9059250911917972 10 Q09472,P54619 2 +Negative regulation of muscle cell differentiation 0.3978751849215157 0.4396972759827292 0.6601563757734321 1.0 0.9059250911917972 11 Q53EL6,P67809,O94826,P25490,Q13485,P51608 6 +Cellular process involved in reproduction in multicellular organism 0.2739085538475754 0.4381872287061528 0.6612505657909644 1.0 0.9065383443074008 52 Q9Y4C1,Q14997,P26583,O95067,P20042,P62753,Q96PU8,P17252,Q9Y2W6,Q9UHB7 10 +Regulation of mitochondrion organization 0.2836974827738575 0.4374746007609158 0.6617671922740707 1.0 0.9065383443074008 43 O14737,O60313,Q9Y6C9,P12235,O00429,P21796,Q96A26 7 +Transforming growth factor beta receptor signaling pathway 0.3048374782276336 0.4373491754691922 0.6618581372226822 1.0 0.9065383443074008 29 Q09472,P49354,Q9UNH7,Q9GZN8,Q06481 5 +Negative regulation of carbohydrate metabolic process 0.3790406829578153 0.4341754372733299 0.664161048391742 1.0 0.9072692187716032 13 Q13043 1 +Regulation of cardiac muscle contraction 0.3572403036970513 0.4336868280329033 0.6645158729964122 1.0 0.9072692187716032 16 Q99996,P16615,Q12959 3 +Negative regulation of hemopoiesis 0.404502168479272 0.4329060146142096 0.6650830502963405 1.0 0.9072692187716032 10 P09429 1 +Negative regulation of viral life cycle 0.4121863799283073 0.4324470219733163 0.6654165487846362 1.0 0.9072692187716032 3 Q12899,Q14258 2 +Negative regulation of viral entry into host cell 0.4121863799283073 0.4324470219733163 0.6654165487846362 1.0 0.9072692187716032 3 Q12899,Q14258 2 +Germ cell development 0.2862392302318458 0.4315505905469532 0.6660680758478426 1.0 0.9072692187716032 40 Q9Y4C1,Q14997,P26583,P62753,Q96PU8,P17252,Q9Y2W6,Q9UHB7 8 +Vascular associated smooth muscle cell proliferation 0.4040914743597548 0.431182892159063 0.6663353922581186 1.0 0.9072692187716032 10 Q14344,Q53EL6,Q9Y2S7,P09601 4 +Sodium ion transmembrane transport 0.3240909012073494 0.4311336181808832 0.6663712176188348 1.0 0.9072692187716032 23 P46939,Q96PU5,P35754,Q6P4Q7,P50570,Q12959 6 +Response to acid chemical 0.3336800482367053 0.430170028614638 0.6670719622735986 1.0 0.9072788161259556 20 Q14103,P42345,Q9UQB8 3 +Morphogenesis of a polarized epithelium 0.3497882008181885 0.4288700009674632 0.6680178327841464 1.0 0.907983197366974 17 P15311,P26038 2 +Regulation of defense response 0.2670557723595818 0.4284647552264805 0.6683127882648858 1.0 0.907983197366974 103 Q7Z739,Q09472,Q15648,Q15233,Q9BY67,Q3LXA3,P04062,Q16512,O75844,Q13177,P26583,Q8WXF1,Q16543,Q15366,Q8TAT6,P19174,Q8TDB6,O94874,Q06481,Q14166,Q9UNH7,Q8NCG7,P09429,Q9UJ41,P27361,Q9NUD5 26 +Development of secondary female sexual characteristics 0.4109570773335327 0.4278848235317188 0.6687349768674635 1.0 0.907983197366974 3 Q15648 1 +Development of secondary sexual characteristics 0.4109570773335327 0.4278848235317188 0.6687349768674635 1.0 0.907983197366974 3 Q15648 1 +Stress activated protein kinase signaling cascade 0.2808884609676499 0.4275831368965909 0.668954645306 1.0 0.907983197366974 45 P15311,P36507,P09429,O15344,Q12959 5 +Positive regulation of neurogenesis 0.2837317213753578 0.426741069611339 0.6695679334090867 1.0 0.9080632446857232 41 P61160,P29373,P42345,O14744,Q9UQB8,P55209,P27695 7 +Positive regulation of nervous system development 0.2837317213753578 0.426741069611339 0.6695679334090867 1.0 0.9080632446857232 41 P61160,P29373,P42345,O14744,Q9UQB8,P55209,P27695 7 +Membrane raft organization 0.3943189542850165 0.4242402024861674 0.6713906441572339 1.0 0.9097789335070824 11 Q9UNF0,P50897,Q12959 3 +Fatty acid transport 0.3485796610867022 0.4224884940142958 0.6726684973006127 1.0 0.9109430615031746 17 P23786,P29373,P14174 3 +Aspartate family amino acid metabolic process 0.3260898894956818 0.4219415224963457 0.6730677013196116 1.0 0.9110000144882444 22 Q13126,O60568 2 +Protein transport along microtubule 0.4438135086670576 0.4213505296361886 0.6734991376243837 1.0 0.911311501583398 5 P78559,P04792,P33176,O60282 4 +Regulation of rig i signaling pathway 0.4376759831969186 0.4204663140834859 0.6741448328087287 1.0 0.9117545407151584 6 Q9NUD5,Q8TAT6 2 +Actin filament polymerization 0.2817090317090061 0.4203557640333796 0.6742255784745486 1.0 0.9117545407151584 43 P35241,P52907,Q01082,P42345,P47755,Q92747,Q9Y2A7,Q9UEY8,Q9UQB8,O95429,Q96F07,P59998,Q9NYL9,P63000,Q13813,Q12959 16 +Regulation of phosphatidylinositol 3 kinase signaling 0.4086796303083864 0.4182022583329643 0.6757992447684793 1.0 0.912342960562494 9 Q10713,O95630,Q9NZM5,P49815 4 +Regulation of hippo signaling 0.4366797594120652 0.4168955377269441 0.6767548175872253 1.0 0.9132134086799966 6 Q01085,P35240 2 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4422864973974545 0.4160288760376231 0.6773888733654505 1.0 0.9133257074325436 5 P62136 1 +Deoxyribonucleoside metabolic process 0.4077060931899505 0.4159169122006081 0.6774708035812389 1.0 0.9133257074325436 3 P04183,P00491 2 +Positive regulation of regulated secretory pathway 0.4362471712173981 0.4153486855351691 0.6778866656843774 1.0 0.9135357588376808 6 P51159 1 +Negative regulation of endothelial cell proliferation 0.447652572400871 0.4150850706882185 0.6780796280632639 1.0 0.9135357588376808 4 P25705 1 +Cellular response to starvation 0.2917326342443497 0.4147184767258505 0.6783480048108241 1.0 0.9137046603499356 35 Q99570,P21964,P42345,P54646,P27361,P04062,P54619,Q96EE3,Q8NEZ5 9 +Regulation of cation transmembrane transport 0.2749543175747554 0.4141424958042545 0.6787697523387124 1.0 0.913718421060858 49 P46939,P17252,P35754,Q96PU5,P50570,P21796,Q99996,Q99623,P27695,Q12959 10 +Epithelial cell apoptotic process 0.3469561354987097 0.4139602330511697 0.6789032306128735 1.0 0.913718421060858 17 Q13043 1 +Vacuolar transport 0.2713222426748614 0.4134803015135498 0.6792547517605021 1.0 0.913718421060858 52 Q14108,P07602,Q8TDB6,Q9P2R3 4 +Negative regulation of peptidyl tyrosine phosphorylation 0.3995388679312922 0.4122418383831545 0.6801621740596719 1.0 0.9144205678880746 10 Q99816,Q9UNH7,P35240 3 +Glycerolipid biosynthetic process 0.2758350155902996 0.4108617532482451 0.6811739087070621 1.0 0.9145030794121496 48 P42356,Q6UWP7,P48426,Q86TV6,Q6IAN0,Q08AM6,P48651,Q9UBF8,Q92643,P35790,Q96N66,Q8WTV0,Q10713,Q01968 14 +Protein catabolic process 0.2306752460702316 0.4089756185794538 0.6825575538789264 1.0 0.9146551533088036 290 Q14997,O95376,Q9UJX5,Q9NUJ1,Q93034,Q8WUX9,Q6GQQ9,Q6ZXV5,P04062,Q7L5D6,Q8IXB1,P33908,Q9UHG3,Q96CS3,P51572,Q8NEZ5,Q92993,Q96HY6,Q9P0J0,Q9Y263,P15311,O43242,P42345,Q9H2J4,P62081,Q99816,Q16850,P55036,Q15366,Q96TA2,Q8WW12,Q9UJX4,Q9H1A4,Q9H3F6,Q96JB5,Q8TAT6,P24941,O00231,Q8TDB6,Q96PU5,Q9UKS6,Q15650,P61289,P17252,P49721,P35241,O60502,Q8TCT9,Q8N511,P50897,Q96RU2,Q96A33,P26038 53 +Positive regulation of fat cell differentiation 0.4238489261114891 0.4077000571445435 0.683493895507546 1.0 0.915158219549086 7 Q13043 1 +Definitive hemopoiesis 0.4453264480508797 0.4072589850751256 0.6838177833029542 1.0 0.9154040725815548 4 Q96JB5,Q13951 2 +Nucleosome mobilization 0.398247192365645 0.406922352004104 0.6840650186646671 1.0 0.9155158697405066 10 Q96EZ8 1 +Actin nucleation 0.3640308960821655 0.4063701706613069 0.68447063371491 1.0 0.9155158697405066 14 Q13576,P61160,Q9BR76,P14373,P59998,P60983 6 +Arp2 3 complex mediated actin nucleation 0.3640308960821655 0.4063701706613069 0.68447063371491 1.0 0.9155158697405066 14 Q13576,P61160,Q9BR76,P14373,P59998,P60983 6 +Response to sorbitol 0.4050347400035596 0.4061903631026099 0.6846027343447245 1.0 0.9155158697405066 3 O95251 1 +Negative regulation of translational initiation 0.4232226480260945 0.4053928861535539 0.685188739234663 1.0 0.91573657838325 7 P12270,Q9BPZ3 2 +Myeloid leukocyte mediated immunity 0.3450804475635675 0.4041721493776851 0.6860861323504126 1.0 0.916555030852357 17 Q9UJ41,P09601,Q9UNH7 3 +Animal organ regeneration 0.3384758044591138 0.4039867313941874 0.6862224763629508 1.0 0.916555030852357 18 P04818,P09601,P62841,Q15648 4 +Regulation of membrane potential 0.2660337149912412 0.4023063979982945 0.6874585466156566 1.0 0.9177298126462424 60 Q96PU5,P04062,Q9UQB8,Q9BSK2,Q99996 5 +Regulation of protein containing complex assembly 0.2647073092682867 0.4019860917642207 0.6876942620668527 1.0 0.9177694793963764 112 Q09472,P23381,Q9NZM5,Q9Y2A7,P04062,Q9UQB8,Q16512,P04350,Q99996,Q9UBB9,Q12959,P45880,O14795,P50542,P42345,P47755,Q96F07,Q9NWH9,P35241,P16949,O94887,P30622,P09429,Q9Y295,P59998,P26038,P51608,P63000,Q13813 29 +Digestive system process 0.3804150086822239 0.40013289233694 0.6890586388219686 1.0 0.9186510065275112 12 P15311,Q8WTV0 2 +Positive regulation of execution phase of apoptosis 0.4032721582662689 0.3998268998444416 0.6892840164298539 1.0 0.9187637849716558 3 P63167 1 +Microtubule anchoring 0.38013335018027 0.3988958307231698 0.6899699613859585 1.0 0.9191398559011024 12 O75381,Q8IWJ2,Q9UIS9 3 +Negative regulation of type i interferon mediated signaling pathway 0.4372443066350254 0.3986506640724626 0.6901506249934828 1.0 0.9191398559011024 5 Q7Z739 1 +Non motile cilium assembly 0.3798165231012614 0.3975058763746344 0.6909944540453021 1.0 0.9196022071907122 12 P50570,Q9UIS9,P27695 3 +Regulation of monocyte chemotaxis 0.4423825095620827 0.3974436469858431 0.691040334671047 1.0 0.9196022071907122 4 Q4KMQ2,P09429 2 +Regulation of alternative mrna splicing via spliceosome 0.2960554860237245 0.3967765050714749 0.6915322778470765 1.0 0.9198610341743696 30 Q8IY67,P31483,Q9UHX1,P51116 4 +Positive regulation of nlrp3 inflammasome complex assembly 0.3630934607345453 0.3961958074936916 0.6919605839358318 1.0 0.9198677190130428 2 O00571 1 +Retina homeostasis 0.4022136510960806 0.3960263618710532 0.6920855808081581 1.0 0.9198677190130428 3 P51790 1 +Amyloid precursor protein catabolic process 0.3616785212217059 0.3952406702033239 0.6926652804562994 1.0 0.9200760472741318 14 P27695,Q15392 2 +Liver morphogenesis 0.4016335324989926 0.3939502055475075 0.6936178026810336 1.0 0.9209663845974416 3 Q15648 1 +Dna damage response signal transduction by p53 class mediator 0.3364804341028407 0.3933178171435047 0.6940847603152382 1.0 0.9212152508643544 18 Q01664,P14174,Q92993,P61254 4 +Negative regulation of developmental growth 0.3699936803452949 0.3925198816816738 0.6946741241641936 1.0 0.9216188929244822 13 Q13043 1 +Pyrimidine nucleotide metabolic process 0.3362835763167224 0.3922698622542758 0.6948588292462117 1.0 0.9216765690367434 18 P13051,P04818,Q9H773 3 +Regulation of endoplasmic reticulum unfolded protein response 0.4188839437973907 0.3895492481651166 0.6968698870793988 1.0 0.9227140349316988 7 Q96HY6 1 +Regulation of cell cycle checkpoint 0.3777812635849871 0.3886169451214796 0.6975595298257016 1.0 0.9227140349316988 12 P15927,Q5JVF3 2 +Response to heat 0.280992097273522 0.3884517176155841 0.6976817779189237 1.0 0.9227140349316988 40 Q09472,Q96EY1,P42345,P12270,P09601,Q9H078,Q13144,Q99543,P17252 9 +Response to wounding 0.2603260925672255 0.3880081789297724 0.6980099809520808 1.0 0.9227140349316988 86 O75122,P53582,Q96G23,Q9BR76,P49257,Q9UNN8,P09601,Q8WUX9,P51159,P42785,Q03001,Q16512,P38435,P17252,Q99623,Q8WTV0,P00374,P63000 18 +Fertilization 0.2898758580826003 0.3879848856363122 0.6980272187319252 1.0 0.9227140349316988 34 P45880,P55769,Q9Y2W6 3 +Cellular response to chemical stress 0.2595664478850072 0.3879542076174568 0.6980499216817146 1.0 0.9227140349316988 84 Q9NR28,Q15233,O15111,P09601,P54646,P04062,Q12846,P00390,P16615,P27695,P00374 11 +Regulation of lysosomal lumen ph 0.4337910377039421 0.3869247822959087 0.6988118937612418 1.0 0.9227140349316988 5 Q8N511,P50897 2 +Metanephric glomerulus development 0.3607046879665546 0.3869111995468005 0.6988219496300105 1.0 0.9227140349316988 2 O95747 1 +Oligodendrocyte differentiation 0.3259849467528019 0.3864333653387017 0.6991757436005595 1.0 0.9227140349316988 20 O14744,P42345,P18074,Q13144 4 +5 phosphoribose 1 diphosphate metabolic process 0.4389005079175583 0.3859658864137938 0.6995219336262151 1.0 0.9229842577526648 4 Q14558,P11908,O60256 3 +Cotranslational protein targeting to membrane 0.376779746713317 0.3842685197811964 0.7007794377790835 1.0 0.923927637803747 12 P49458,P09132,P43307,O76094 4 +Female gamete generation 0.3087218802114708 0.3832093186335482 0.7015645691828623 1.0 0.9247445725080506 25 Q9Y2W6,O95067 2 +Positive regulation of actin filament polymerization 0.3588596961375401 0.3820385491343805 0.7024327713199843 1.0 0.9254010437089504 14 Q9UQB8 1 +Cytoskeleton dependent intracellular transport 0.2641259628077701 0.381587458292947 0.7027673883877381 1.0 0.9254010437089504 59 Q14254,O60313,Q00839,Q03001,O75381,Q13409,Q5SNT2,Q9UIS9,P27695 9 +Gamete generation 0.2633823214269419 0.3812170827423064 0.7030421742987594 1.0 0.9254447579124296 108 Q14997,Q9BY67,Q9BPZ3,P51572,P50570,P54619,Q15019,P26583,O95067,Q14141,Q96PU8,Q9Y2W6,P25490,O75718,P16104,P17252,Q9UHB7,Q9P0K7,P62753,P20042,Q9Y4C1,Q9BTX1 22 +Positive regulation of chromosome separation 0.3910096046308866 0.377579726417509 0.7057428276728042 1.0 0.9256885463037064 10 Q9UJX5,Q14674,Q14980,Q9UJX4,Q9UJX2 5 +Intracellular protein transport 0.2235889582139812 0.3771017947289201 0.7060979574974233 1.0 0.9256885463037064 323 O60830,Q99595,O43615,O95376,Q15648,P09132,Q9Y5J9,P49257,P83436,P51572,P55735,O75381,Q9NS69,P33908,P40855,Q7L5D6,Q14108,Q96CS3,Q9Y282,Q9H267,Q9P0J0,Q8N4H5,P50542,Q13043,Q12846,Q8TAT6,P27695,Q10713,O43681,O14737,P12270,Q8IWJ2,P49458,Q06481,Q9P2W9,P17252,Q9UIS9,O60725,Q9Y5L4,Q9C0E2,Q9UNH7,Q8TCT9,P51159,Q9UJ41,Q92544,Q9Y3B3,Q15036,P61960,Q8N1F7 49 +Regulation of oocyte maturation 0.3580173186025622 0.3765870523027786 0.7064805113407593 1.0 0.9256885463037064 2 Q8IXJ6 1 +Positive regulation of cell maturation 0.3580173186025622 0.3765870523027786 0.7064805113407593 1.0 0.9256885463037064 2 Q8IXJ6 1 +Regulation of cell maturation 0.3580173186025622 0.3765870523027786 0.7064805113407593 1.0 0.9256885463037064 2 Q8IXJ6 1 +Transport along microtubule 0.2671928037456021 0.3747049403564425 0.7078799176548864 1.0 0.9268909194654472 52 Q14254,O60313,Q00839,Q03001,O75381,Q13409,Q5SNT2,P27695 8 +Regulation of protein binding 0.2663012986282593 0.3739308623839121 0.7084557544556045 1.0 0.9269010131470078 53 Q09472,Q08379,Q13043,Q8TDB6,Q6IAN0,P27361,O75381,P62136,P30533,P17252,P16615,Q9Y2S7,Q9UBB9,Q7KZI7 14 +Cardiac muscle contraction 0.3108162351048542 0.3722745876741015 0.7096884171934335 1.0 0.9274017082223348 24 Q96PU5,Q99996,P16615,Q12959 4 +Myeloid cell differentiation 0.2586007421110074 0.3719652700557683 0.7099187074879647 1.0 0.9274017082223348 85 Q96AX1,Q09472,Q15648,Q6IAN0,P04062,P12814,Q00534,P26583,P42345,O00625,Q96JB5,O94874,P48426,O95251,Q13310,Q99873,P35579,P17252,Q9GZZ9,P18074,O94887,Q86XI2,P62753,Q6NYC1 24 +Protein complex oligomerization 0.2621497236420229 0.3706602110220397 0.7108906294991524 1.0 0.9274017082223348 64 Q9Y285,P14174,Q08379,Q13043,O60313,P54132,Q96GX9,Q99873,O00429,Q04837,Q96TA2,Q06481,Q6NYC1,Q9H3F6,Q9UJZ1 15 +Nucleotide excision repair 0.3172870151465949 0.3700399834402501 0.7113526990923456 1.0 0.9275300128424868 22 P18074,P28340,P15927,O95251,P35244,Q9HCS7,P54725 7 +Tetrahydrofolate interconversion 0.4231232079851527 0.3695191082710619 0.711740833074904 1.0 0.9277695778865472 6 P04818 1 +Xenobiotic metabolic process 0.3556031506138481 0.3669739137424885 0.7136384763794932 1.0 0.9292108333704254 14 P07099 1 +Microtubule based transport 0.2655328997043012 0.366741309278606 0.713811989951818 1.0 0.9292513557601364 53 Q14254,O60313,Q00839,Q03001,O75381,Q13409,Q5SNT2,P27695 8 +Positive regulation of spindle assembly 0.3553299492385725 0.3663936564260466 0.7140713525861613 1.0 0.9292912622182196 2 Q14980 1 +Protein hexamerization 0.4220202208667867 0.3657679390091748 0.7145382454960856 1.0 0.9293465859149082 6 Q96RR1,Q96TA2 2 +Positive regulation of b cell activation 0.3639955885026608 0.3656889726071746 0.7145971756238139 1.0 0.9293465859149082 13 P14174 1 +Regulation of trans synaptic signaling 0.2624267279497479 0.3647740440721068 0.7152800818466278 1.0 0.9296789113983456 59 P17252,Q9BPZ3,Q8IUD2,Q9UNF0,Q9UQB8,Q99996,P16615,P27695,Q4J6C6 9 +Trna processing 0.2705527428930847 0.3638004477794443 0.7160070282473274 1.0 0.9298829584760316 48 Q2VPK5,Q12849,O15091,Q96PZ0,P05455,O60294,Q969Y2,Q9Y606,Q9NXG2,O75127,Q9BXR0,Q9NNW5,Q96FX7 13 +Regulation of macrophage differentiation 0.4314117772780408 0.3617791913261994 0.7175170432669546 1.0 0.9309340683372938 4 P17252 1 +Positive regulation of macrophage differentiation 0.4314117772780408 0.3617791913261994 0.7175170432669546 1.0 0.9309340683372938 4 P17252 1 +Ubiquitin recycling 0.4312544597331315 0.3612785750393603 0.7178912083074018 1.0 0.9309340683372938 4 Q16763,Q9Y263 2 +Cell cycle process 0.2302001012674118 0.3611264058404564 0.7180049543286753 1.0 0.9309340683372938 381 Q16181,P35580,Q15648,Q6UVJ0,Q99623,P08183,Q9NVM9,O95067,P61254,O14744,Q9UJX4,Q9Y2W6,Q9Y2S7,Q13561,O43663,Q5JVF3,Q14566,Q9UJX2,Q9BW19,Q68E01,Q9NNW5,Q9NQG5,Q9NS87,P16949,Q86XI2,P62753,P02545,Q01664,P53985,P51608,Q9BTX1,Q86XL3,Q8WUX9,Q9NZM5,Q9UNZ2,P42695,O75844,O95235,Q15019,Q12959,P25205,P46379,Q9BZD4,Q00534,P15311,Q6NUQ1,Q14141,Q14674,Q16763,P51530,P27695,Q9BV86,Q13464,Q01082,O95905,P19447,P23246,Q06481,P33991,P35579,P41227,P35241,Q99570,Q92547,Q9P0V9,Q96EE3,Q96DE0,Q9UNS1,O60885,Q96BK5,P49959,Q7Z7L1,O95630,Q15257,Q96HY6,Q96EA4,Q99986,Q9NUQ3,Q9UNM6,P15927,Q9H1A4,Q6DKK2,P24941,Q99459,P17252,P18074,Q08379,Q96RU2,Q9UQE7,Q9UJX5,Q93034,P50570,P23258,O00139,P61160,Q00839,Q96JB5,Q12873,P12270,O14757,P16104,P61289,Q9UIS9,O75122,P54132,Q9BSJ2,Q9Y295 107 +Negative regulation of cell adhesion 0.2862121430035206 0.3609447648072669 0.7181407386417522 1.0 0.9309340683372938 34 P35241,P35240,P06576,P09429,Q12959 5 +Regulation of cellular carbohydrate metabolic process 0.2937502534289068 0.36043688436357 0.7185204478716594 1.0 0.9309575556080288 29 Q14108 1 +Regulation of attachment of spindle microtubules to kinetochore 0.3999401734968559 0.357686836363146 0.7205776853014987 1.0 0.9317467956431444 8 P14635,Q9P258,Q9H0H5,Q8IXJ6,P25054,Q00839,Q9H8V3 7 +Positive regulation of immune system process 0.2587875990988178 0.3571508246238197 0.7209788975516012 1.0 0.9320737490930564 124 Q09472,Q15648,Q15233,Q9BY67,Q9NR50,Q16512,Q96FZ2,Q99623,P46379,Q13177,Q14254,P15311,P26583,P09601,Q4KMQ2,Q8WXF1,Q12846,Q13144,P14174,P19174,O43290,O00429,Q5JVF3,P23246,Q06481,Q96EY1,P17252,Q9UJZ1,O15400,P09429,Q9UJ41,P27361,Q9NUD5,P63000 34 +Lipid homeostasis 0.3082167444203512 0.3565449585545694 0.7214324892174737 1.0 0.9321062016696166 24 Q9Y6C9,O15254,P54646,Q5BJF2,Q8WTV0 5 +Regulation of protein localization to cell periphery 0.289230294116321 0.3555453936815202 0.7221810441449881 1.0 0.9327040360360562 31 P15311,Q14651,O00264,Q12959 4 +Hindlimb morphogenesis 0.3901992779431408 0.3540345805681774 0.7233129678603922 1.0 0.9331067461308212 3 Q15648 1 +Embryonic hindlimb morphogenesis 0.3901992779431408 0.3540345805681774 0.7233129678603922 1.0 0.9331067461308212 3 Q15648 1 +Stress granule assembly 0.3412344698328052 0.3537554424860579 0.7235221686239974 1.0 0.9331067461308212 16 Q7Z739,P31483,Q14157 3 +Establishment of protein localization 0.2373509411850211 0.3536657645081452 0.7235893824037434 1.0 0.9331067461308212 519 O60830,P24390,P35580,Q99595,O95376,Q15648,Q32P28,P09132,P49257,P83436,Q13555,Q7L5D6,Q9NS69,Q96CS3,Q14108,Q9Y282,Q9P0J0,Q13043,O95070,O75695,Q8TDB6,Q5JVF3,O60725,Q9Y5L4,Q8TCT9,P50897,Q92544,P61960,P53985,Q8IUD2,Q9BTX1,O43615,Q15006,Q9Y5J9,Q8WUX9,P55735,O75381,P33908,P15311,Q9HD20,Q16850,P27695,Q10713,Q96KC8,P00367,O00429,Q06481,Q9P2W9,P35241,Q9UNH7,P51159,Q9Y3B3,Q96EE3,O15127,Q8N4H5,P50542,Q4J6C6,O14828,O43681,O14737,Q9H089,Q8IWJ2,Q9UPT5,P17252,Q08379,Q9P0I2,Q9UJ41,Q15036,P51572,P50570,P40855,Q9H267,O60318,Q12846,Q8TAT6,P12270,P49458,Q9UIS9,Q9Y4I1,Q86UP2,Q96A33,Q9C0E2,Q8N1F7 83 +Regulation of histone h2b ubiquitination 0.423713351323853 0.3535600165598629 0.723668643389519 1.0 0.9331067461308212 5 Q6PD62,Q5VTR2,Q9NW82 3 +Lamellipodium assembly 0.3351120380864556 0.3533817302146219 0.7238022806016067 1.0 0.9331067461308212 17 P61160,P42345,O94813,Q9Y2A7,P50570,P63000 6 +Negative regulation of small molecule metabolic process 0.3223246354113809 0.3529646168726313 0.7241149670680849 1.0 0.9331067461308212 19 Q06481,Q13043 2 +Deoxyribonucleotide biosynthetic process 0.398336228401209 0.3518552772742297 0.7249468006323867 1.0 0.9331067461308212 8 P55263 1 +Phosphorylation of rna polymerase ii c terminal domain 0.4082217693801042 0.3516956133981707 0.7250665506634071 1.0 0.9331067461308212 7 Q92759,O60885,Q8WUA2,Q9NYV4 4 +Carbohydrate catabolic process 0.265239784915476 0.3500956006873948 0.7262669523789778 1.0 0.933730916317023 51 Q09472,Q9NUJ1,Q3LXA3,P54619,Q14108 5 +Regulation of hydrolase activity 0.2329945461344287 0.3485304922480373 0.7274418181074711 1.0 0.9339995876800312 175 Q86YR5,Q14997,P51572,Q14108,Q99623,Q96HY6,Q15392,Q4VCS5,P49354,Q9P0J0,Q9Y263,P07602,P16435,P26583,P42345,Q8WU90,Q96F07,Q96JB5,Q9NWH9,Q66K14,Q96A26,Q9NR28,Q13576,O14737,P61289,Q5JVF3,Q06481,Q4KMP7,P35241,P16949,P09429,P50897,Q01968 33 +Anatomical structure maturation 0.2805133894854391 0.3481795754066447 0.7277053257323112 1.0 0.9339995876800312 37 P18074,P04818,Q15125,P04062,P17252,Q9Y2W6 6 +Wound healing 0.2596572242134172 0.3478918922680417 0.7279213744375719 1.0 0.9339995876800312 67 P53582,P09601,Q8WUX9,P51159,Q03001,P42785,P38435,P17252,Q9UNN8,Q8WTV0 10 +Positive regulation of metaphase anaphase transition of cell cycle 0.3905061447417787 0.3477713337695712 0.7280119197423685 1.0 0.9339995876800312 9 Q9UJX4,Q9UJX2,Q9UJX5 3 +Negative regulation of transport 0.2543406050177793 0.3473205772239197 0.7283504934877632 1.0 0.9340175516803187 80 Q96PU5,P09429,P09601,Q9UKS6,Q9UJ41,Q16850,P21796,Q9UNF0,Q06481,P61960,P63000 11 +Metal ion transport 0.2602723736858959 0.346927749697793 0.7286455986278728 1.0 0.9340584538668658 100 P35754,Q93034,Q13555,P50570,P21796,Q99996,Q12959,Q9HD20,P27695,O15173,P24941,Q96PU5,Q9UKS6,O00429,P17252,Q9UJZ1,Q9UM00,P46939,P16615 19 +Regulation of cell population proliferation 0.2339330806685216 0.3467686680924972 0.7287651174800618 1.0 0.9340584538668658 239 Q96BK5,P43490,Q15648,P35240,P23381,Q32P28,O76071,Q52LJ0,P25705,Q16512,O95630,O75569,Q99623,Q96HY6,Q15392,Q12959,Q9ULC4,Q13043,P16435,Q00534,P26583,P09601,Q9H2J4,Q00839,Q99816,Q12846,P17096,P14174,O43663,P78362,O14737,P24941,O94874,O14757,P35244,Q99873,Q92974,Q06481,Q9BSK2,Q96EY1,Q14534,P17252,P55209,Q9NNW5,Q9NQG5,Q969Z0,Q96G23,P09429,P62753,P27361,P02545,P43307,Q01664,Q01085,P51608 55 +Amino acid activation 0.2787358037801679 0.3451815962965137 0.7299578534940663 1.0 0.9346886302573236 38 Q9BTE6,P54136,P49591,Q9Y285,Q9HA77,P49589,A2RTX5,P41250,P23381,P49590,Q5T160,P47897,O75879,Q9BW92 14 +Erk1 and erk2 cascade 0.273678794240211 0.344188430218789 0.7307045827148309 1.0 0.9353821315804208 41 P14174,P15311,P36507,P09429,P18615,Q96GX9,O14744,P17252,Q99623,Q12959 10 +Rig i signaling pathway 0.3749854109167219 0.3436715495029399 0.731093309537965 1.0 0.935431122184104 11 Q9NUD5,Q99623,Q8TAT6,Q9H078 4 +Positive regulation of microtubule nucleation 0.4203825891062056 0.3428235041633981 0.7317312425553351 1.0 0.9357785790546964 5 P51608,Q16512 2 +Regulation of microtubule nucleation 0.4203825891062056 0.3428235041633981 0.7317312425553351 1.0 0.9357785790546964 5 P51608,Q16512 2 +Response to prostaglandin 0.4196276053648911 0.340410568220384 0.7335473611310379 1.0 0.9367232567344764 5 P25490 1 +Golgi vesicle transport 0.2573210424152158 0.3374816676184461 0.7357538295281469 1.0 0.9367266436879086 124 Q9Y282,O14828,P24390,O75695,Q08379,Q8TBA6,Q8IWJ2,P51572,Q9Y3B3,Q9P2R3,P55735,P50570,Q9Y2L5,O95070,Q9P2W9,O15127,Q4J6C6 17 +Response to transforming growth factor beta 0.277592541682855 0.3364669601593484 0.7365187626422893 1.0 0.9374519815548102 38 Q09472,P49354,O14737,Q9UNH7,Q9GZN8,Q06481 6 +Mitotic spindle organization 0.2583067899827669 0.3355899332595419 0.7371801162958502 1.0 0.9377850758180738 68 P16949,Q9BZD4,Q9UQE7,O43663,Q08379,O75122,P12270,Q8WUX9,Q9Y295,Q00839,P23258,O00139,Q9BW19,Q9NVM9,Q9Y2S7,Q13561,Q9NS87 17 +Protein k29 linked ubiquitination 0.3840327916790899 0.3333369417765488 0.73887995683327 1.0 0.9386819915381448 3 Q16763 1 +Regulation of response to external stimulus 0.2489455373425742 0.333007197748732 0.7391288499388622 1.0 0.9386819915381448 143 Q7Z739,Q09472,Q15648,Q15233,Q9BY67,Q3LXA3,P04062,P26583,Q12846,Q8WXF1,Q15366,Q8TAT6,Q9NWH9,P14174,Q8TDB6,O00429,Q06481,Q14166,P17252,O75122,Q96G23,Q9UNH7,P80303,Q8NCG7,Q9BR76,P09429,Q9UJ41,Q9NUD5,P63000 29 +Response to amino acid starvation 0.3563385304877698 0.3324179442042005 0.7395736906938546 1.0 0.9386819915381448 13 P27361,P42345,Q96EE3 3 +Enucleate erythrocyte differentiation 0.3836964596284535 0.3322254221335347 0.7397190488290877 1.0 0.9386819915381448 3 Q15648 1 +Regulation of ion transport 0.2534288095372552 0.3315301266594104 0.7402440886445563 1.0 0.938995846567725 81 P14174,Q96PU5,Q9UKS6,P21796,Q99996,P08183,P27695,Q12959 8 +Positive regulation of calcium ion transmembrane transporter activity 0.38581691553154 0.3304263083256217 0.7410778656378674 1.0 0.939471048314626 9 P27695 1 +Regulation of er to golgi vesicle mediated transport 0.4110820606889871 0.3294628143398333 0.7418058962900074 1.0 0.9397879132083992 6 Q9P2W9 1 +Regulation of ubiquitin dependent protein catabolic process 0.2586271595519894 0.3288247168481518 0.7422881796875436 1.0 0.9400684379275974 60 O95376,P24941,O94874,Q9NZM5,Q9H2J4,P62081,P51572,P04062,Q96JB5,P54725,Q8NEZ5,Q96HY6 12 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.4010910272784758 0.3272850372628866 0.7434523083655231 1.0 0.9411749311166894 7 P09601 1 +Regulation of gliogenesis 0.3467520925594417 0.327096979288093 0.7435945364446293 1.0 0.9411749311166894 14 O14744,P42345,Q96G23,P35240 4 +Ribonucleoside triphosphate biosynthetic process 0.2856783564116008 0.3250901312735876 0.745112857769807 1.0 0.9419581817263905 30 Q05682,P18859,P06576,O75964,P56134,P25705,Q9UJZ1 7 +Adaptive thermogenesis 0.2909062589809384 0.3245483063387802 0.7455229564543382 1.0 0.9419715031599248 28 P23786,Q6IAN0,P12235,Q00839,Q06481 5 +Regulation of leukocyte chemotaxis 0.3349005036853771 0.3236071708117922 0.7462354583535145 1.0 0.9424893176333596 16 O00429,P14174,P09429 3 +Polyamine metabolic process 0.4187430594749206 0.322492829300084 0.7470793692251783 1.0 0.9424893176333596 4 P19623,Q9UBN7 2 +Supramolecular fiber organization 0.2271118094764038 0.3220724137886725 0.7473978363120644 1.0 0.9424893176333596 187 Q05682,P35221,O60568,P35240,Q9Y2A7,Q03001,Q14651,Q9UQB8,Q16512,P04350,P23258,Q99996,Q68EM7,O00139,P12814,P67936,Q12959,P52907,Q13177,P15311,Q13485,P61160,P42345,P47755,Q16527,Q96F07,O95429,Q9NWH9,P29372,Q13576,Q13464,Q01082,A0MZ66,P06753,O75718,P08670,Q96AC1,Q92747,Q9NQP4,Q92974,Q99661,Q99471,Q9NYL9,P61758,P07197,Q9UIS9,P35241,P16949,Q9Y4I1,Q6WCQ1,Q08379,O75122,P30622,Q9BR76,O94813,P14373,O15344,Q9Y295,Q9UBN7,Q9UEY8,P13674,P59998,Q9BSJ2,P60983,P51608,P63000,Q13813 67 +Regulation of microtubule depolymerization 0.3455266153096922 0.3217041363531152 0.7476768439525152 1.0 0.9424893176333596 14 Q9UBN7,Q92974,O75122,O15344 4 +Positive regulation of catalytic activity 0.2322522264581978 0.3217028606879375 0.7476778104561954 1.0 0.9424893176333596 224 Q14997,Q96GG9,P51572,P54619,Q04837,Q9BRT9,Q8WTV0,P00374,Q96HY6,Q12959,P49354,Q9P0J0,Q9Y263,Q13043,P07602,P26583,Q14103,Q00839,Q8WU90,Q12846,Q96HR8,Q66K14,Q96A26,Q7KZI7,Q9NR28,P14174,O14737,Q8TDB6,P36507,Q9BTE7,Q4KMP7,Q9NPI6,P09429 33 +Central nervous system neuron axonogenesis 0.4083707025411145 0.3207231194182079 0.7484202253517491 1.0 0.942650496087604 6 P07900,O94813,P43034,P08238,Q99622 5 +Spliceosomal complex assembly 0.2764596964291432 0.3178969117153374 0.7505631352783175 1.0 0.9432264627048528 37 Q9Y383,Q9UHX1,P78362,Q09161 4 +Posttranscriptional regulation of gene expression 0.2323535462698294 0.3174959842528401 0.7508672860823244 1.0 0.9432300538081216 231 Q7Z739,P67809,P34897,Q9BPZ3,Q96EY7,Q567V2,P00374,P46199,Q15024,Q14103,P42345,P57772,Q00839,Q96PU8,Q13144,Q96HR8,P27695,Q10713,Q96KC8,P53582,Q09161,P41567,P36507,P08670,P12270,P49458,Q9HCE1,Q5JVF3,P51116,P17252,Q969Z0,O95900,P04818,Q969T7,Q9NPI6,P55010,Q92552,P27635,Q9H074,P31483 40 +Response to cobalt ion 0.3415945058226277 0.3164336304089661 0.7516733939731566 1.0 0.943754130468968 2 Q14790 1 +Ensheathment of neurons 0.2895702663347395 0.3159847250481555 0.7520141022457638 1.0 0.943754130468968 28 P18074,P42345,Q96PU8,Q13144,Q12959 5 +Neuron cellular homeostasis 0.4115361625821794 0.3150429389436632 0.7527290520300682 1.0 0.943754130468968 5 P78559,Q14203,P51790,Q00535 4 +Somite rostral caudal axis specification 0.3409973126306319 0.3143458498215943 0.7532583786212559 1.0 0.943754130468968 2 Q13485 1 +Regulation of cell matrix adhesion 0.2866031955037652 0.3130046663378431 0.7542771169377329 1.0 0.943754130468968 29 Q13464,O75122,Q00534,P35240,P46939,O75116,Q96AC1,Q13630,P63167,P63000,Q9Y2S7 11 +Negative regulation of epithelial cell proliferation 0.3433535444478177 0.3122209629209405 0.7548726017547882 1.0 0.943754130468968 14 Q99623,Q00534,Q15648,Q12959 4 +Membrane protein proteolysis 0.3669842414245399 0.3122050993057373 0.7548846569812104 1.0 0.943754130468968 11 Q8TCT9 1 +Negative chemotaxis 0.3775388291517207 0.3122014408316311 0.7548874371714478 1.0 0.943754130468968 3 Q15375,O94813 2 +Negative regulation of oxidative phosphorylation 0.3775388291517207 0.3122014408316311 0.7548874371714478 1.0 0.943754130468968 3 P30405,Q6L8Q7 2 +Organelle assembly 0.2321055983824587 0.311811551995522 0.7551837442302962 1.0 0.943754130468968 244 Q16181,Q7Z739,Q9UQE7,P62841,Q9Y4Z0,Q9H2M9,Q9NZM5,Q8WUX9,Q96FJ2,Q567V2,Q6UVJ0,Q14651,Q86Y56,P50570,Q14157,O00139,P57076,Q15019,P15311,P61160,Q9Y5K8,O95067,P54646,Q14141,Q00839,Q99816,Q9Y2S7,P27695,Q66K14,O75695,O43663,P24941,P48426,P08865,P12270,Q9Y2L5,Q4KMP7,Q14534,Q9P2W9,Q9BW19,Q9UIS9,P46782,Q9NS87,P35241,O94887,Q08379,O75122,O15400,P27635,Q9BSJ2,P31483,P26038,P16615,Q9Y295,Q01968 55 +Phosphatidylinositol 3 phosphate biosynthetic process 0.4150974318272843 0.3115857999027138 0.7553553273952422 1.0 0.943754130468968 4 Q01968 1 +Regulation of mrna splicing via spliceosome 0.2562774680457432 0.3114575805647548 0.7554527860408309 1.0 0.943754130468968 64 P78362,Q09161,Q13595,Q9UHX1,Q8IY67,Q00839,Q96PU8,P51116,Q6NYC1,P31483 10 +Regulation of telomere capping 0.37372439367568 0.3109311854973982 0.755852936119878 1.0 0.943754130468968 10 Q14103,P27361,P18887 3 +Sugar mediated signaling pathway 0.3769414575866104 0.3102922030086638 0.7563387598532176 1.0 0.943754130468968 3 P51532,P17480 2 +Carbohydrate mediated signaling 0.3769414575866104 0.3102922030086638 0.7563387598532176 1.0 0.943754130468968 3 P51532,P17480 2 +Retinal rod cell development 0.339802926246634 0.3101920967135751 0.7564148802399933 1.0 0.943754130468968 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.339802926246634 0.3101920967135751 0.7564148802399933 1.0 0.943754130468968 2 P54802 1 +Retinal rod cell differentiation 0.339802926246634 0.3101920967135751 0.7564148802399933 1.0 0.943754130468968 2 P54802 1 +Nervous system process 0.2576873426731212 0.3099172792492506 0.7566238623814889 1.0 0.943754130468968 107 O75695,Q9Y5L4,Q9Y5J9,O00264,P50897,P04062,Q9UQB8,Q14108,Q00169 9 +Negative regulation of mononuclear cell migration 0.339504329650636 0.3091582210360866 0.7572011729033623 1.0 0.9439340696021667 2 O94813 1 +Regulation of peptidase activity 0.2526481855697021 0.3085293537844905 0.7576795678203805 1.0 0.9441914002096212 77 Q96A26,Q9NR28,Q14997,Q9P0J0,P09429,Q5JVF3,Q06481,Q96HY6,Q15392 9 +Osteoblast differentiation 0.2651229296370265 0.3084255647113003 0.7577585316719588 1.0 0.9441914002096212 47 O60506,Q00534,P62841,P06576,Q00839,Q96A33,P17252,P67936 8 +Positive regulation of receptor clustering 0.3392057330546357 0.3081261769615162 0.7579863232758512 1.0 0.9441914002096212 2 Q15334 1 +Cytoplasmic translational initiation 0.3087711876862569 0.3066383217340721 0.7591186813826534 1.0 0.9448550748874888 21 Q9ULC4,P42345,Q9NR50,P55010,P20042 5 +Imp salvage 0.3757467144563836 0.3064916957197018 0.7592303016699604 1.0 0.9448550748874888 3 P00492,P07741 2 +Regulation of reproductive process 0.3195070422155183 0.3062397351787704 0.7594221204669656 1.0 0.9448977613283922 18 Q13043 1 +Positive regulation of cyclin dependent protein kinase activity 0.4085475194261728 0.3059064931384229 0.7596758420006151 1.0 0.9449447330981122 5 Q99741,P14635,P08238,O75909 4 +Cellular protein catabolic process 0.2316745972405104 0.30580980063629 0.7597494659156903 1.0 0.9449447330981122 248 Q14997,O95376,Q9UJX5,Q93034,Q9NZM5,Q8WUX9,Q9UNZ2,Q6GQQ9,Q6ZXV5,P04062,Q7L5D6,Q8IXB1,P33908,Q9UHG3,Q96CS3,P51572,O75844,Q8NEZ5,Q92993,Q96HY6,P46379,Q9Y263,P15311,O43242,Q5T4S7,Q9H2J4,P62081,Q99816,P55036,Q15366,Q96TA2,Q8WW12,Q9UJX4,Q9H1A4,Q9H3F6,Q9NXV2,Q96JB5,Q8TAT6,P24941,O00231,Q8TDB6,O94874,Q96PU5,Q15650,P61289,P17252,Q9UJX2,P49721,P35241,Q5VTR2,Q8TCT9,Q8N511,P26038,P50897,Q96RU2,Q96A33,P54725 57 +Pigmentation 0.3310039930885529 0.3055175116938505 0.7599720347342513 1.0 0.9450414441074168 16 Q9Y4I1,Q96AX1,Q9H267,P51159,Q13561 5 +Hematopoietic stem cell differentiation 0.3649945280314988 0.30456477472194 0.7606976518079602 1.0 0.9451015313008122 11 P18074,O94874,Q00534 3 +Regulation of cellular protein catabolic process 0.253813599349831 0.3037367743320271 0.7613284389049613 1.0 0.9451015313008122 88 P35241,O95376,P24941,P15311,O94874,P26038,Q96JB5,Q9NZM5,Q9H2J4,P62081,P51572,Q6ZXV5,P04062,P61289,P17252,P54725,Q8NEZ5,Q96HY6 18 +Deoxyribonucleoside monophosphate biosynthetic process 0.4025713074995943 0.3023900486975573 0.7623547398816672 1.0 0.945122916502234 6 P55263 1 +Regulation of neurogenesis 0.2555310361237328 0.3020888508439673 0.7625843313881584 1.0 0.94522798606631 62 Q96G23,P35240,P61160,P26583,P29373,P42345,P55209,O14744,Q9UQB8,Q06481,Q9UIS9,Q9UBS4,P27695 13 +Membrane docking 0.2915788365029902 0.3018700144883065 0.7627511550058435 1.0 0.945255229314116 26 Q13464,O14795,P15311,O60763,O15400,O15498,Q12846,P26038,P16615 9 +Forebrain morphogenesis 0.3371155568826437 0.3009534263186504 0.7634500093675365 1.0 0.9459416671981286 2 Q9Y5K5 1 +Regulation of synaptic vesicle exocytosis 0.3639378477118923 0.3005379644261128 0.7637668425983075 1.0 0.9461545965824896 11 P16615 1 +Amino sugar metabolic process 0.3833749037907049 0.299402784847693 0.7646327375704585 1.0 0.9466881512777104 8 Q06210,O60502 2 +Programmed cell death 0.2325882660465707 0.2988412717372534 0.7650611587449851 1.0 0.9470389078091376 438 P24390,O15269,Q15648,Q9Y2C4,P04062,P21796,Q9NS69,Q8IXB1,Q16512,Q99623,Q9NYF8,Q15392,Q14185,P45880,Q9P0J0,O14795,Q13043,P16435,P42345,P09601,P61254,Q96F07,P14174,Q2TAL8,O94874,Q8WYA6,Q92974,Q5JVF3,Q96EY1,Q9Y2J2,P09429,P50897,P62753,P27361,P02545,P62136,Q01664,P61960,Q01085,P51608,Q9UDX5,Q15233,Q86XL3,Q9UHX1,Q9NZM5,Q9Y2A7,P25705,Q8IYB8,O75569,O75844,P12814,Q6PJG6,P46379,Q13177,Q9BXJ9,Q9H2J4,Q14674,Q4KMQ2,Q9BXK5,P27695,Q96A26,Q9NR28,Q13464,P78362,P19174,Q9Y6C9,P17987,O00429,P19447,P23246,Q9UNH7,P12235,P31483,P35240,Q9Y3A2,O95630,Q96HY6,P26583,O60313,Q96GX9,Q96TA2,O14737,P17252,P18074,Q96RU2,P27635,Q09472,Q9BY67,Q93034,P51572,P50570,Q6FI81,Q9H0S4,Q9NYV6,P13051,P54646,P62081,Q12846,Q13144,Q96JB5,Q9NWH9,O14757,P61289,Q9NVI7 104 +Positive regulation of behavior 0.3724611708482551 0.2961649969772218 0.7671040786909133 1.0 0.947884865207802 3 Q9Y6A4,Q96QK1 2 +Phosphatidylinositol metabolic process 0.2863393564079006 0.29554118340628 0.767580496712897 1.0 0.947884865207802 28 P42356,Q6UWP7,P19174,P48426,Q86TV6,Q08AM6,Q9UBF8,Q92643,Q96N66,Q96S52,Q10713,Q01968 12 +Establishment of protein localization to vacuole 0.3287798542704964 0.2953542096224046 0.7677233091854907 1.0 0.947884865207802 16 Q14108 1 +Muscle cell migration 0.3622865714790049 0.2942884654671724 0.7685374858418859 1.0 0.9483210468514456 11 Q13464,Q96N67,Q9BR76,Q14344,P27695 5 +Histone h2a acetylation 0.3621533795948273 0.293786693231932 0.7689209038851899 1.0 0.9483210468514456 11 Q86UY6,Q9UBU8 2 +Programmed necrotic cell death 0.3225290100523073 0.2925024033549618 0.7699025225825826 1.0 0.9484523915227075 17 O00429 1 +Mononuclear cell migration 0.2972323994242931 0.2922943876791428 0.770061549531234 1.0 0.9484523915227075 24 P04062,P09429 2 +Nucleobase containing compound transport 0.2562281911532166 0.2922755653452742 0.7700759395889263 1.0 0.9484523915227075 109 P67809,P05455,Q09161,Q9H2D1,P12235,P55735,Q5JVF3,Q96PU8,Q9BSK2,Q9BTX1 10 +Negative regulation of cellular respiration 0.4081793085792159 0.291398848670819 0.7707462949881436 1.0 0.9488200097734536 4 P30405 1 +Central nervous system projection neuron axonogenesis 0.4081266806094972 0.2912478925434425 0.7708617364111019 1.0 0.9488200097734536 4 P43034,Q99622,O94813 3 +Endoplasmic reticulum organization 0.2684976998683451 0.2905864065721968 0.7713676576549242 1.0 0.948995434998474 40 P46379,O43681,P50542,Q15006,Q9H2M9,P49257,Q9P0I2,Q7L5D6,O00429,Q96A33,Q9P2W9,Q9Y5P4 12 +Regulation of nervous system development 0.2534789997298404 0.2880500082388951 0.7733084590633514 1.0 0.948995434998474 69 Q96G23,P35240,P61160,P26583,P29373,P42345,P55209,O14744,Q9UQB8,Q06481,Q9UIS9,Q9UBS4,P27695,Q12959 14 +Positive regulation of dna dependent dna replication 0.3979057445789871 0.2880070944773936 0.7733413080527227 1.0 0.948995434998474 6 Q04837,P24941 2 +Negative regulation of telomere capping 0.4069315805198834 0.2878306701574522 0.7734763589881832 1.0 0.948995434998474 4 Q92878,Q92889,P18887 3 +Nucleoside phosphate biosynthetic process 0.2545995070530405 0.2849896492357868 0.7756520719641824 1.0 0.9505925674438036 97 P18859,P43490,P53007,P04818,P06576,P50897,Q9BQG2,O75964,Q4G176,P56134,Q53GQ0,P55263,Q9UJZ1,Q9Y3D8 14 +Positive regulation of ubiquitin protein ligase activity 0.3687306643510273 0.2846647463062572 0.7759010019900514 1.0 0.9507191023257744 3 Q16763 1 +Positive regulation of cell cycle g1 s phase transition 0.3090225329429653 0.2843641908264981 0.7761312982954736 1.0 0.9508227619065628 19 P35241,Q6UVJ0,P27695,Q96HY6 4 +Protein targeting to vacuole 0.3315122566333311 0.2835844014107368 0.7767288924349913 1.0 0.9508831267101812 15 Q14108 1 +Lamellipodium morphogenesis 0.3963087282491563 0.2831604588362467 0.777053837676974 1.0 0.9508831267101812 6 Q9BR76,O60749,Q92766 3 +De novo pyrimidine nucleobase biosynthetic process 0.3994506627010787 0.278900941539834 0.7803208459568678 1.0 0.952589442741808 5 Q05682 1 +Regulation of binding 0.2549448213399333 0.2782788923457456 0.7807982779091036 1.0 0.952589442741808 104 Q09472,Q96BK5,Q86YR5,Q6IAN0,O75381,P40855,Q96HY6,Q13043,P26583,P09601,Q7KZI7,O14981,Q09161,Q8TDB6,P17252,P18074,P16949,Q08379,P09429,P16615 20 +Positive regulation of stress activated protein kinase signaling cascade 0.3302740465704539 0.2782417397517002 0.7808267956916171 1.0 0.952589442741808 15 P09429,O15344 2 +Monocyte chemotaxis 0.3859205147177319 0.2779508554053715 0.7810500844069386 1.0 0.952589442741808 7 Q4KMQ2,P09429,P17931 3 +Podosome assembly 0.3945658075611356 0.2779162711581079 0.7810766331767414 1.0 0.952589442741808 6 P26038 1 +Positive regulation of cell matrix adhesion 0.3430608400316707 0.2775503447271457 0.7813575540533935 1.0 0.9526441656016996 13 Q13464,P46939,Q00534,Q13630,P63000,Q9Y2S7 6 +Cell cycle g1 s phase transition 0.2524978444762428 0.2755318948529011 0.7829076251876483 1.0 0.9532677664895208 67 P35241,Q00534,P24941,P15927,Q93034,P62753,Q6UVJ0,P61289,Q06481,Q99623,P27695,Q96HY6,Q12959 13 +Positive regulation of gliogenesis 0.3760600554313072 0.2751058402179934 0.7832349247976544 1.0 0.9532677664895208 8 O14744,P42345 2 +Negative regulation of leukocyte cell cell adhesion 0.3344997980699585 0.2746744775782861 0.7835663411570328 1.0 0.9532677664895208 14 P09429 1 +Heart valve morphogenesis 0.3759173464163202 0.2746410408589267 0.7835920322635754 1.0 0.9532677664895208 8 Q13485,P42345,Q13464,O94813 4 +Negative regulation of myelination 0.3290534487906779 0.2741491784589615 0.7839699820332913 1.0 0.9532677664895208 2 Q13614 1 +Negative regulation of nervous system process 0.3290534487906779 0.2741491784589615 0.7839699820332913 1.0 0.9532677664895208 2 Q13614 1 +Epithelial tube morphogenesis 0.2598941971826509 0.2732195290252193 0.7846844688980783 1.0 0.9537121315713656 48 Q9NWH9,Q15648,P49815,Q13043,Q13485,O60313,O94813,P62081,Q14344,Q9UNS1,P62136,Q16512,P63167,P17252,Q99623,P25440,P67870,Q12959 18 +Protection from non homologous end joining at telomere 0.4011489967784127 0.2715905584292787 0.7859368599555785 1.0 0.9538555428790028 4 Q9UBB9 1 +Negative regulation of actin filament depolymerization 0.3232101324593548 0.2704393722727102 0.7868222534483156 1.0 0.9538555428790028 16 P35241,P52907,Q01082,P47755,Q9UEY8,Q13813 6 +Growth plate cartilage development 0.3637324931020906 0.2696393692279054 0.7874377094907508 1.0 0.9538555428790028 3 P16435 1 +Bone growth 0.3637324931020906 0.2696393692279054 0.7874377094907508 1.0 0.9538555428790028 3 P16435 1 +Negative regulation of meiotic cell cycle 0.3275604658106845 0.2693388443161113 0.7876689427788761 1.0 0.9538555428790028 2 Q15645 1 +Positive regulation of transport 0.2290294803425636 0.2688365677730703 0.788055451870765 1.0 0.9538667572692704 174 P35580,O95376,P35754,Q6P3W7,P51572,P50570,Q99996,P08183,Q12959,Q9Y282,O14795,O75323,Q9Y263,P15311,Q12846,P27695,P14174,O14737,P00367,Q96PU5,P12270,O00429,Q06481,Q9P2W9,P17252,Q9UIS9,P35241,O75122,P51159,P50897,Q92544,Q9P2R3,Q9C0E2,P26038 34 +Mitotic cell cycle 0.2189874507955211 0.2687569865681303 0.7881166955556094 1.0 0.9538667572692704 322 P35580,Q6UVJ0,Q99623,P08183,Q9NVM9,O95067,P61254,O14744,Q9UJX4,Q9Y2S7,Q13561,O43663,Q5JVF3,Q14566,Q9UJX2,Q9BW19,Q68E01,Q9NS87,P16949,Q86XI2,Q5VTR2,P30622,P62753,Q01664,P51608,Q86XL3,Q8WUX9,Q9NZM5,Q9UNZ2,P42695,O75844,O95235,Q12959,P25205,Q9BZD4,Q00534,Q6NUQ1,Q14141,Q14674,Q16763,P51530,P27695,Q13464,Q01082,O95905,P19447,Q06481,P41227,P35241,Q96EE3,Q96BK5,P04350,O95630,P15927,Q9H1A4,Q6DKK2,P24941,Q14166,P17252,P18074,Q08379,Q9UQE7,Q9UJX5,Q93034,P50570,P23258,O00139,Q00839,Q96JB5,P12270,O14757,P35244,P61289,O75122,P54132,Q9BSJ2,Q9Y295 77 +Regulation of cyclin dependent protein kinase activity 0.3012861173642006 0.2674846658619345 0.7890960190639253 1.0 0.9546979274028878 21 Q96JB5,O95067,P54132,Q01664 4 +Endothelial cell chemotaxis 0.3951234444687467 0.2664918065904489 0.7898604687294821 1.0 0.9549146756073732 5 Q9BR76 1 +Lamellipodium organization 0.2953655243474961 0.2646052022833455 0.7913136121055855 1.0 0.9556358531032596 23 P61160,Q9BR76,O60749,P42345,O94813,Q9Y2A7,P50570,P18206,P63000 9 +Deoxyribonucleoside monophosphate metabolic process 0.3727996466646063 0.2645766579397373 0.7913356037649426 1.0 0.9556358531032596 8 P55263 1 +Regulation of behavior 0.3898832890496264 0.2640643038378508 0.7917303692856237 1.0 0.9558465970169426 6 P42345,Q15334 2 +Pyrimidine containing compound metabolic process 0.283111177856336 0.2627105676486064 0.7927736710139337 1.0 0.9561339820803793 27 Q05682,P04818,P13051,Q9H773,Q9HC21 5 +Regulation of protein adp ribosylation 0.3892780712649543 0.2622994351928696 0.7930905974367386 1.0 0.9562648149745387 6 Q9NWY4 1 +Regulation of dna templated transcription initiation 0.310273440991583 0.2619301066021726 0.7933753279891649 1.0 0.9562648149745387 18 Q15648,Q9NYV6,Q9Y2X0,O75448,P09429 5 +Protein localization to golgi apparatus 0.3807010612446405 0.2618409951389686 0.7934440317958433 1.0 0.9562648149745387 7 P49755,P83436,Q8IWJ2 3 +Protein localization to nucleolus 0.3463915248768158 0.2612277559854065 0.793916874845314 1.0 0.956275659881971 12 Q96EZ8,Q96D46,Q96BK5 3 +Regulation of myelination 0.346208285546059 0.2605427147172767 0.7944451710700127 1.0 0.956603115392086 12 P42345,Q96P11,Q13614,Q12959 4 +Positive regulation of cell activation 0.2622288058586637 0.258622450372917 0.7959265595370699 1.0 0.9574157788855002 42 P14174,Q14254,O43290,P09429,Q12846,Q5JVF3,Q96FZ2 7 +Negative regulation of immune response 0.2941943541504101 0.2583444311274371 0.7961410986656636 1.0 0.9574157788855002 23 Q14166,Q7Z739,P09601 3 +Proteolysis 0.228376005792162 0.2582891065424544 0.7961837928304643 1.0 0.9574157788855002 404 Q14997,Q9UJX5,P67812,O95376,P34897,Q93034,Q8WUX9,P51572,Q6ZXV5,P04062,P42892,P33908,Q6GQQ9,Q9UHG3,O95630,Q7L5D6,Q8IXB1,Q9HB40,Q96CS3,Q8NEZ5,Q92993,Q96HY6,Q15392,Q96FZ2,Q9Y4A5,Q9P0J0,Q9Y263,Q13043,P50579,P16435,O43242,Q9H2J4,P62081,Q99816,Q92643,P55036,Q15366,Q96TA2,Q8TAT6,Q9H1A4,Q9H3F6,Q8WW12,Q96JB5,Q96F07,Q10713,Q4J6C6,Q96A26,Q9UJX4,Q9NR28,P36551,P53582,Q96KC8,O14737,Q8TDB6,Q96PU5,P24941,O00231,Q9UKS6,P22695,P42785,Q15650,Q5JVF3,P61289,Q06481,Q9BWJ5,P17252,Q9H4L4,P49721,Q9UJZ1,Q8TCT9,P09429,Q96RU2,Q9UBW8,Q96DE0,Q96A33,Q9NUQ7 76 +Regulation of epithelial cell migration 0.2589216416543382 0.2578234630039585 0.7965431556503293 1.0 0.957518521754316 47 Q14185,O75122,P19174,P06576,P42345,P09429,P09601,P42785,Q9UBN7,P25705,P63000,P17252,Q9NWH9,P51608,Q8WTV0,P67870 16 +Negative regulation of cysteine type endopeptidase activity 0.3149520095718335 0.2577687798092078 0.7965853605222861 1.0 0.957518521754316 17 Q15392 1 +Negative regulation of cell cycle g1 s phase transition 0.3143613983237254 0.2551261267194412 0.7986256855003389 1.0 0.9582680741222817 17 P15927,P24941,Q12959 3 +Dna replication 0.250052996161073 0.254518341225728 0.7990951362815595 1.0 0.9582680741222817 127 Q9UQE7,P49959,Q04837,Q7Z7L1,O75844,Q9BRT9,P25205,P28340,P15927,Q9NR33,Q99543,P51530,Q9BQ67,Q9Y2S7,P17096,P46063,P78362,P24941,P25490,O95251,O14757,P35244,Q96RR1,Q9Y3Z3,Q9BUQ8,P33991,Q9UBD5,Q96EY1,Q14566,Q9UJZ1,Q92547,Q5W0B1,Q96EZ8,P33992,P54132,Q9UBZ9,Q9UNS1,P55209,Q8WVB6 39 +Negative regulation of ubiquitin protein transferase activity 0.3292870042372531 0.2534245670750719 0.7999401453582873 1.0 0.9587425893441404 14 Q8TDB6 1 +Peptidyl proline modification 0.2717999512297702 0.2518593677004677 0.801149767198174 1.0 0.9595329500327294 33 Q9BV86,Q32P28 2 +Negative regulation of apoptotic signaling pathway 0.2501165918305196 0.2516146972775086 0.8013388972665403 1.0 0.9595481914791636 65 P45880,P14174,Q9P0J0,P09601 4 +Positive regulation of cell projection organization 0.2499176574559384 0.2512518315883317 0.8016194136307007 1.0 0.95968978193359 68 Q09472,Q16181,P61160,Q32P28,Q9BR76,P29373,P50570,Q9UQB8,Q14108,P63000,P27695,Q7KZI7 12 +Positive regulation of molecular function 0.2186887487971388 0.2510812976621985 0.8017512551489325 1.0 0.95968978193359 325 Q09472,Q96BK5,Q14997,Q86YR5,Q96D46,P35754,Q96GG9,P51572,P50570,P54619,Q8IXB1,Q04837,Q16512,Q99996,Q9BRT9,P08183,Q8WTV0,P00374,Q96HY6,Q12959,Q99623,P49354,Q9P0J0,Q9Y263,O75323,Q13043,P07602,O15111,P26583,Q14254,Q14103,P16435,P42345,Q00839,Q8WU90,Q12846,Q96F07,Q96HR8,P27695,Q9NWH9,Q66K14,Q96A26,Q7KZI7,Q9NR28,Q9Y2S7,P14174,O14737,Q09161,Q8TDB6,P36507,Q08AM6,P61289,Q92974,Q9BTE7,Q4KMP7,Q9UBS4,P18074,P16949,Q86U42,Q9NPI6,P09429,P14373,P15880,Q5JTV8,P27361,Q01664,Q8IUD2,Q8WVB6 68 +Dna strand elongation involved in dna replication 0.3358686480915944 0.2494444204523312 0.8030170282463709 1.0 0.9603241939409596 13 P18858,P09884,P33991,P51530,Q07864,P40938,P25205 7 +G protein coupled receptor signaling pathway 0.2535637753340676 0.2484232640013572 0.8038069355624831 1.0 0.9607468930912544 51 P16949,P15311,P07602,Q8NCG7,P50570,P42892,Q06481,P63000,P17252,Q9NWH9 10 +Homeostatic process 0.2201260203753618 0.2484165346929415 0.8038121416301331 1.0 0.9607468930912544 301 P30519,Q15648,Q93050,Q6IAN0,P51572,P04062,Q16512,Q14157,Q9Y487,Q8WTV0,P28340,Q9Y263,Q00534,Q9NYV6,P26583,O95067,P09601,Q9HD20,O15254,Q5BJF2,P54646,Q12846,Q96JB5,Q9Y5P4,P27695,Q9NWH9,P14174,P12277,Q96PU5,P06576,Q9Y6C9,Q99873,P42785,Q06481,Q8NE01,P17252,Q9UJZ1,Q9UM00,P18074,P16949,Q8N511,P23786,P09429,P50897,P62753,Q92544,Q6NYC1,Q96A33,P00390,P53985,P16615,Q9Y4C1 52 +Axonal transport 0.2922823925774307 0.2482236564485672 0.8039613638110876 1.0 0.9607492877185786 23 Q03001,P27695 2 +Gastrulation with mouth forming second 0.3881934691445272 0.2472246755129045 0.804734349606244 1.0 0.9611056539579438 5 Q4VCS5 1 +Inner cell mass cell proliferation 0.3672356837333469 0.2470493827121462 0.804870006385445 1.0 0.9611056539579438 8 Q9BRT9,O14757 2 +Positive regulation of chemotaxis 0.3070207147710567 0.2468866607534282 0.8049959400144224 1.0 0.9611056539579438 18 P09429,P27361,Q12846,O00429,P63000,Q9NWH9 6 +Cristae formation 0.3669925340769306 0.2462963117150404 0.8054528648508441 1.0 0.9612520831795438 8 Q9NVH1 1 +Regulation of neutrophil chemotaxis 0.3750637301159877 0.244961676321962 0.8064861052856842 1.0 0.9621124934585016 7 O00429 1 +Negative regulation of calcineurin mediated signaling 0.3910637758750804 0.2444643170594809 0.8068712345538429 1.0 0.9621124934585016 4 P42345,Q9UHD1 2 +Negative regulation of calcium mediated signaling 0.3910637758750804 0.2444643170594809 0.8068712345538429 1.0 0.9621124934585016 4 P42345,Q9UHD1 2 +Regulation of cyclase activity 0.366306613965162 0.2441777929789201 0.8070931252361653 1.0 0.962187129165569 8 Q99996 1 +Negative regulation of cell matrix adhesion 0.3661880121225441 0.2438123635108317 0.8073761445465302 1.0 0.962187129165569 8 P35240 1 +Regulation of small gtpase mediated signal transduction 0.2570090739123916 0.2426775084926715 0.8082552323051639 1.0 0.9626644494898556 47 P49815,Q13017,Q96AG4,P50570,Q14344,O95630,Q68EM7,Q4VCS5,O95140,Q92888,Q9H3F6,Q07960,Q9NWH9,Q92974,Q9H8V3,P35241,P16949,Q13618,O75955,O94813,Q9UJ41,P63167,P63000 23 +Inner ear receptor cell development 0.3657723200558283 0.2425336124677247 0.8083667151707645 1.0 0.9626644494898556 8 P54802,Q14651,Q9BW83 3 +Negative regulation of lymphocyte activation 0.316663923898796 0.2421771537975572 0.8086428968417616 1.0 0.962817650937664 16 P09429 1 +Regulation of transcription by rna polymerase iii 0.33390698691857 0.2419864900506965 0.8087906315614071 1.0 0.9628178879185958 13 Q9H2U1,P42345,P55199,P30044 4 +Locomotory exploration behavior 0.3536439665471818 0.2406864183891735 0.8097981661306579 1.0 0.9636657243195976 3 Q9HB07,Q15334 2 +Bone development 0.2724701432598693 0.2397629538144772 0.8105140279102334 1.0 0.9643417586403252 30 Q09472,Q15648,P16435,Q32P28,P48426,Q15125 6 +Single fertilization 0.2788873618915639 0.2379970777402114 0.8118833607192075 1.0 0.9655382773928785 27 P45880,P55769 2 +Rna 5 end processing 0.3397932019439852 0.237028846664922 0.8126344114344908 1.0 0.9655382773928785 12 P05455,O15091 2 +Cell activation involved in immune response 0.2611619818610719 0.2367079215279418 0.8128833891024203 1.0 0.9655764465384774 40 Q9UNH7,P13051,P09429,P09601,P51159,P62753,Q9UJ41,Q12846,Q96FZ2 9 +Plasma membrane raft assembly 0.3513308347148875 0.2343135005457547 0.8147416057102146 1.0 0.966452640881862 3 Q9UNF0 1 +Plasma membrane raft organization 0.3513308347148875 0.2343135005457547 0.8147416057102146 1.0 0.966452640881862 3 Q9UNF0 1 +Tubulin complex assembly 0.3832649830180918 0.2339867236494283 0.8149952855933273 1.0 0.966452640881862 5 P61758 1 +Cell part morphogenesis 0.2480350953114879 0.2328822714277698 0.815852825341064 1.0 0.9669915616011232 128 Q96N67,Q9Y2A7,P50570,P42892,Q9UQB8,Q16512,P35613,Q04837,Q8IYB8,Q9Y263,Q13177,P61160,Q96F07,Q9Y5P4,Q9Y2S7,Q9NZM3,Q7KZI7,Q13464,A0MZ66,Q96PU5,O60749,O00429,Q9HCE1,Q06481,P16949,Q9Y2J2,Q9H2U1,Q9BR76,O00264,P29373,Q9UNF0,P63000 32 +Positive regulation of protein localization 0.2471621011008863 0.2307950896567636 0.8174739961500368 1.0 0.9683854236476928 130 P35580,Q96BK5,O95376,P51572,Q14651,Q96HY6,Q12959,Q9Y282,O14795,P15311,P54646,Q12846,Q96JB5,O14737,P00367,Q8TDB6,P12270,O00429,P17252,Q9UIS9,P35241,Q96EZ8,O00264,Q92544,Q9C0E2,P26038 26 +Cellular response to hormone stimulus 0.2422084836872631 0.229530141118056 0.8184568966447832 1.0 0.9691593369590852 141 Q09472,P43490,Q15648,Q9UQB8,Q16512,Q99623,Q96HY6,P16435,P54646,Q00839,P27695,O15173,O94874,P48426,Q15650,P42785,Q06481,Q9BSK2,P17252,P35241,Q9Y4I1,P61960,Q9Y4C1,Q9NS86,Q9NUQ7 25 +Stem cell division 0.3851871988660875 0.2293809689639975 0.8185728264355621 1.0 0.9691593369590852 4 Q01085 1 +Linoleic acid metabolic process 0.3144222155867359 0.2291507454441258 0.8187517534337243 1.0 0.9691953460744576 2 O95864 1 +Regulation of phospholipase activity 0.3559081531048408 0.2288692918157993 0.8189705086899233 1.0 0.9692364749887252 9 P50897 1 +Regulation of mrna catabolic process 0.2440707455818478 0.2276930862492803 0.819884847650499 1.0 0.9692364749887252 79 Q7Z739,P67809,Q15024,O60506,Q969T7,Q9NPI6,Q14103,P08670,Q00839,Q9HCE1,Q5JVF3,P51116,Q9H074,P17252,P27695,Q969Z0 16 +N acetylglucosamine metabolic process 0.3844875403125172 0.227621345602884 0.8199406241277294 1.0 0.9692364749887252 4 O60502 1 +Positive regulation of histone ubiquitination 0.3804542737597043 0.2266133693649082 0.8207243954798307 1.0 0.9692364749887252 5 Q6PD62,P50750,O75150,Q5VTR2 4 +Atrioventricular valve development 0.3135264257987399 0.2265538058496027 0.8207707158494744 1.0 0.9692364749887252 2 Q13485 1 +Negative regulation of protein containing complex disassembly 0.2696282995516772 0.22634142814258 0.8209358793194022 1.0 0.9692364749887252 31 P35241,P52907,O75122,Q01082,P47755,O15344,Q9UBN7,Q92974,Q9UEY8,Q13813,P29372 11 +Regulation of synaptic plasticity 0.2785189962707682 0.2259703743474951 0.8212244622353833 1.0 0.9692364749887252 26 Q8IUD2,Q9UQB8 2 +Negative regulation of epithelial cell migration 0.3545816602027635 0.2247557383309487 0.8221693007902215 1.0 0.9692884293385108 9 P51608,P09429,P67870 3 +Establishment of mitotic spindle localization 0.3216269125988139 0.2234137000537489 0.8232135426781457 1.0 0.9695570140094656 14 O75122,Q13257,Q9UNZ2,Q14674,Q14980,P53350,Q96EA4 7 +Regulation of ossification 0.3356008296637339 0.2221658564577564 0.8241847725333846 1.0 0.9703463513535752 12 P27361,Q4KMQ2,O75844 3 +Positive regulation of g1 s transition of mitotic cell cycle 0.3211950359098089 0.2217660861703137 0.824495981403726 1.0 0.9705357148462502 14 P35241,Q99741,Q7L2J0,Q6UVJ0,O00571,P27695 6 +Regulation of toll like receptor signaling pathway 0.3479008391163531 0.2215771793418272 0.8246430491606584 1.0 0.9705357148462502 10 P09429,Q06481 2 +Response to x ray 0.3281626610953838 0.2206770439080887 0.8253439071260908 1.0 0.9710103367414582 13 Q70UQ0,P50570 2 +Notch signaling pathway 0.3111815833176825 0.2193971007366018 0.8263407282947797 1.0 0.9715611656729344 16 Q8TDB6 1 +Mammary gland epithelial cell proliferation 0.3773960042530199 0.2187378903469477 0.8268542314047622 1.0 0.9715611656729344 5 Q15648 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.2951201159737727 0.218039953558308 0.8273979817978836 1.0 0.9719540274152972 19 Q9H078,Q3LXA3,Q9NUD5,Q8TAT6,Q99623 5 +Regulation of granulocyte chemotaxis 0.3512172936547936 0.2144805223505991 0.8301723544709152 1.0 0.9735318571926672 9 P27361,O00429,P63000 3 +Base excision repair gap filling 0.3455401649437388 0.2140802149792554 0.8304845042966285 1.0 0.9737229383830036 10 P27695 1 +Rhythmic behavior 0.3752891694214478 0.2134025907849953 0.8310129598932099 1.0 0.9739925603920776 5 P42345 1 +Peptidyl tyrosine modification 0.2545517393998526 0.2127604137799191 0.8315138419922714 1.0 0.9744046207293164 45 P14174,Q86XI2,P35240,P36507,Q9UNH7,P42345,Q9H2J4,P27361,Q99816,Q92974,Q9NWH9 11 +Regulation of rho protein signal transduction 0.3091146106878059 0.2110262073671953 0.8328668212924799 1.0 0.975458737036404 16 P16949,Q13618,O75955,Q92974,P63167,Q9H3F6,Q9NWH9,P63000 8 +Regulation of signaling receptor activity 0.3040361526770648 0.2105184310610121 0.8332630680571376 1.0 0.975458737036404 17 Q86XI2,Q9UNH7,Q96FZ7,Q9UBN7,Q99816,P30533,Q99996 7 +Cellular iron ion homeostasis 0.3089695513854744 0.2104432980768056 0.8333217022027266 1.0 0.975458737036404 16 Q9Y487,P09601 2 +Mechanoreceptor differentiation 0.3443771147965417 0.2104301482659532 0.833331964474286 1.0 0.975458737036404 10 P54802,Q14651,Q9BW83 3 +Ossification 0.2456384590643504 0.210291799314511 0.8334399353913189 1.0 0.975458737036404 68 P18074,P51659,Q9NUQ3,O60506,P62841,Q00534,Q13485,P06576,O94874,Q9H2U1,Q15125,Q00839,Q4KMQ2,P27361,Q96A33,P17252,O75844,P67936 18 +Myoblast differentiation 0.3318290735788157 0.2091438615008656 0.83433593521553 1.0 0.975458737036404 12 Q15650,Q14254 2 +Regulation of map kinase activity 0.2787909393511022 0.2091174878663128 0.8343565231592411 1.0 0.975458737036404 25 P04062 1 +Response to cell cycle checkpoint signaling 0.3416965352449129 0.2088639025857548 0.8345544842041319 1.0 0.9755154153530656 3 Q14683,O75844 2 +Regulation of mitotic centrosome separation 0.3765292018614871 0.20815661590343 0.8351066820719755 1.0 0.9758713414683328 4 O14757 1 +Histone h4 deacetylation 0.3726838015540876 0.2069072924213774 0.8360822612257828 1.0 0.9764267782318288 5 Q9H4L7,Q9UKL0,Q8IXJ6,Q13547 4 +Cellular macromolecule biosynthetic process 0.2310850080402745 0.2050389146736278 0.8375417213481984 1.0 0.9772441069445352 583 P34897,P23381,P83436,Q567V2,P04062,P00374,P28340,Q15024,Q9ULC4,P42345,P57772,P61254,Q16540,P46778,Q96PU8,Q92643,Q99543,Q9Y2S7,P17096,P53582,O60506,Q09161,P35573,P08670,P84098,Q13310,Q96A35,Q96EY1,Q14566,P62899,Q96S52,O95900,Q9Y673,Q7LGA3,Q969T7,P62753,P15880,P27361,Q7Z7H8,P62136,P46776,Q99805,Q9Y3D3,Q8WVB6,Q7Z739,P67809,P62841,Q9H2M9,Q9NR50,Q9Y5P6,P33908,Q04837,O75844,P25205,P46199,P04844,Q9HA77,Q7Z478,Q5T160,Q96RP9,P51530,Q9BQ67,P50914,Q10713,P46063,Q96KC8,P78362,Q13084,P41567,Q13464,O95251,Q15650,P62917,P17987,P51116,P33991,Q9UBD5,Q9BW92,P62266,P62750,P46782,Q96PZ0,P04818,Q92547,Q96EZ8,P61513,Q9H2U1,P55010,Q9NRK6,Q9UNS1,P55209,P31483,P04183,Q8N5C6,Q96BK5,P04843,O60568,P49589,P60228,P61247,Q9BPZ3,P62854,Q96EY7,Q6ZXV5,P49959,O75879,Q9BTE6,P15927,Q8WU90,Q9H6U8,P24941,P25490,P25398,Q99873,Q9UPR3,Q9HCE1,P29692,Q08379,O60502,Q9NPI6,Q9UBZ9,P27635,P20042,Q10472,Q9Y285,Q9UQE7,P46976,Q9BRT9,Q2TAA5,Q14103,P62081,Q00839,Q13144,Q9NR33,Q96HR8,P08865,P12270,O14757,P35244,P49458,Q9UJZ1,P33992,P54132,Q02543,Q92552,Q9H074,Q9Y295 147 +Dna ligation 0.3480423844161847 0.2049941093786483 0.8375767273345722 1.0 0.9772441069445352 9 P09429 1 +Atp metabolic process 0.2488366952140304 0.2047159788686899 0.8377940354674516 1.0 0.9772441069445352 109 Q09472,O43678,P34897,O43676,O75964,P54619,O75323,P51970,P54646,O75306,P06576,Q9UDW1,P22695,P56134,O00429,Q9BSK2,Q9UJZ1,P18859,O75380 19 +Eye photoreceptor cell development 0.3399044205495712 0.2043272691283771 0.8380977617745273 1.0 0.9772441069445352 3 P54802,Q8NBN7 2 +Regulation of nuclease activity 0.3526671757678061 0.203894649052744 0.838435826684178 1.0 0.9772516886838624 8 P09429 1 +Mitotic spindle assembly 0.2577913920065318 0.2036220060353062 0.8386488950813027 1.0 0.9773034108146116 39 Q9UQE7,O43663,Q08379,O75122,P12270,Q8WUX9,Q9Y295,Q00839,O00139,Q9BW19,Q9Y2S7 11 +Rrna pseudouridine synthesis 0.3712799215082414 0.2034546191003361 0.8387797125302849 1.0 0.9773034108146116 5 Q96HR8 1 +Epidermal cell differentiation 0.2639877760354097 0.202206627519562 0.8397551921395461 1.0 0.9775291660530172 33 P18074,Q13464,Q15648,Q13043,Q14651,Q99816,Q8NEY8 7 +Protein processing 0.251683842408117 0.2017288271370913 0.8401287250790639 1.0 0.9775291660530172 47 P67812,P50579,Q8TCT9,P42892,Q96TA2,P17252,Q10713,Q15392 8 +Response to organic cyclic compound 0.2194881172812433 0.2011428817714467 0.8405868523292885 1.0 0.9775291660530172 184 Q09472,Q15648,P50570,P04062,Q16512,P35613,Q99996,Q99623,P00374,Q92993,Q96HY6,P07099,P16435,P15311,P26583,P61160,Q14103,O14744,Q00839,Q13126,P27695,O15173,P28288,P35573,O94874,O14757,Q15650,P17252,Q9GZZ9,P49721,P04818,P26038,P54132,Q15126,P27361,Q9NUD5,P61960,P53985,Q9Y4C1,Q9NUQ7 40 +Cytosolic transport 0.2442577034065851 0.1993937923651857 0.8419547159678431 1.0 0.9785568079084852 70 Q9BXI6,P51151,Q15075,P49257,P15311,P61160,O15498,Q4J6C6,P33176,P36507,P48426,O60749,Q8IWJ2,Q4KMP7,P35241,Q99570,Q9Y5X3,Q9UNH7,P14373,P27361,Q9P2R3,Q8N1B4,P26038,Q8IUD2,Q13614 25 +Energy homeostasis 0.3458821046575798 0.1986574266117148 0.8425307288192878 1.0 0.9785696982535744 9 P42785 1 +Neurotransmitter secretion 0.2868434948076985 0.1969781364426462 0.8438446471734959 1.0 0.9785696982535744 21 Q12846,P16615,Q4J6C6,P50897 4 +Nuclear pore complex assembly 0.3447259345102107 0.1953056869728467 0.8451536452411366 1.0 0.9787727745052762 9 P12270,Q9BTX1 2 +Regulation of toll like receptor 3 signaling pathway 0.3362022660789616 0.195154139850765 0.8452722798078445 1.0 0.9787727745052762 3 Q14254 1 +Phosphatidylinositol 3 kinase signaling 0.3204197167210387 0.1932418499617451 0.8467695648389488 1.0 0.9799642099909524 13 Q969H8,P49815,Q9NZM5,O95630,Q10713 5 +Cellular response to lipid 0.2475339802514174 0.1926418307251813 0.847239482303374 1.0 0.9800386358133296 115 Q09472,Q15648,Q16512,Q99623,Q8WTV0,Q92993,Q96HY6,Q9P0J0,Q9Y263,P26583,Q14103,Q00839,O15173,P14174,O94874,P08670,Q15650,P17252,Q9GZZ9,Q86U42,P09429,P27361,P61960,P26038,Q9Y4C1,Q9NS86,Q9NUQ7 27 +Natural killer cell activation 0.3431258408529026 0.1907128594016978 0.8487505632652683 1.0 0.9807706652714324 9 P46379,O95251,P51159 3 +Associative learning 0.3260339133566388 0.1897973802064128 0.8494679088756227 1.0 0.98104512239078 12 P61160,P51608,O00264,P50897 4 +Regulation of neutrophil migration 0.3475251180262556 0.1896439477830842 0.8495881467313999 1.0 0.98104512239078 8 O00429 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.3373865824076775 0.1891059726190223 0.8500097604742529 1.0 0.98127518530519 10 P14174,P61254 2 +Bone cell development 0.342372377956784 0.188568669436782 0.8504308903961759 1.0 0.98127518530519 9 Q09472,Q15648 2 +Positive regulation of interleukin 2 production 0.3470830835154723 0.1884433870314233 0.8505290909462884 1.0 0.98127518530519 8 Q9UJZ1 1 +Establishment of epithelial cell polarity 0.330941651351113 0.1864236519110434 0.8521125459890457 1.0 0.98127518530519 11 P15311 1 +Regulation of b cell activation 0.297842669805317 0.1852687353402649 0.8530182590780719 1.0 0.9815576632700332 17 P14174 1 +Negative regulation of actin filament polymerization 0.2876425220346708 0.1848887080666383 0.8533163279571898 1.0 0.9815576632700332 19 P35241,P52907,Q01082,P47755,Q9UEY8,Q9NYL9,Q13813 7 +Regulation of endocytic recycling 0.2979994028067995 0.1845386981189264 0.8535908717109075 1.0 0.9815918993454418 2 Q07960 1 +Gmp metabolic process 0.2925225100219057 0.1837023186128681 0.8542469898764282 1.0 0.9818273786427564 18 Q9NRG1,P55263,Q12959 3 +Xenophagy 0.3654018524051387 0.1826675251343421 0.8550588981697853 1.0 0.982288081433113 4 Q9Y4P8,P27361,Q676U5 3 +Regulation of cytosolic calcium ion concentration 0.2792279881696652 0.1826159281795412 0.8550993856300206 1.0 0.982288081433113 23 P19174,Q15334,P09429,O95202,P51572,Q14344,P17252,P27695 8 +Regulation of alcohol biosynthetic process 0.365103077382731 0.1820112952155828 0.85557386166404 1.0 0.9823220822872664 4 P16435,O75477,O94905 3 +Regulation of cholesterol biosynthetic process 0.365103077382731 0.1820112952155828 0.85557386166404 1.0 0.9823220822872664 4 P16435,O75477,O94905 3 +Steroid hormone mediated signaling pathway 0.2507249954534048 0.1811988932801243 0.8562114632582061 1.0 0.9826728411673268 44 O15173,Q09472,Q15648,O94874,Q15650,Q16512,P61960,Q99623,Q9Y4C1,Q96HY6,Q9NUQ7 11 +Cellular response to dexamethasone stimulus 0.3585861829836859 0.1808542918094521 0.8564819469806901 1.0 0.9826728411673268 6 P25705,Q01664 2 +Response to interleukin 4 0.3440023930601223 0.1801849460135304 0.8570073763498018 1.0 0.9826728411673268 8 P39023,P12268,P33993,P08238,P11802,P49327,P49736 7 +Carbohydrate derivative transport 0.3011931191580834 0.1800878829655666 0.8570835750823578 1.0 0.9826728411673268 16 P07602,Q8WTV0 2 +Regulation of megakaryocyte differentiation 0.3438912430325126 0.1798905504519846 0.8572384938312498 1.0 0.9826728411673268 8 P26583 1 +Regulation of actomyosin structure organization 0.262389037318823 0.1797896907305337 0.8573176773410354 1.0 0.9826728411673268 30 P16949,Q13464,O75122,Q13177,P35240,Q13485,P42345,Q96AC1,O95429,Q16512,Q9H8V3,P63167,P63000,Q9NWH9 14 +Positive regulation of g protein coupled receptor signaling pathway 0.3639770889874337 0.1795515118034149 0.8575046738725103 1.0 0.9826728411673268 4 P17252 1 +Peptide metabolic process 0.2247159831944437 0.179424859998357 0.8576041126617109 1.0 0.9826728411673268 399 P34897,P23381,Q567V2,Q8N4J0,P00374,Q15024,Q9ULC4,Q9H7Z7,P42345,P57772,P61254,Q16540,P46778,Q96PU8,P53582,O60506,Q09161,P08670,P84098,Q13310,Q96A35,P62899,O95900,Q969T7,Q8TCT9,O43708,P62753,P15880,Q7Z7H8,P62136,Q9Y3D3,Q7Z739,P67809,P62841,P46199,Q9HA77,P50914,P27695,Q10713,Q96KC8,P41567,Q15650,P62917,P51116,Q9BW92,P46782,P04818,P61513,P55010,P31483,Q8N5C6,P67812,Q9BPZ3,Q96EY7,O75879,Q9BTE6,Q8WU90,P25398,Q9HCE1,P29692,Q9NPI6,P27635,P00390,P20042,Q9Y285,P42892,Q14103,P62081,Q00839,Q13144,P08865,P12270,P49458,Q02543,Q92552,Q9H074,Q9Y295 77 +Mitotic metaphase plate congression 0.2645296951367529 0.1793015247334499 0.8577009496902734 1.0 0.9826728411673268 29 Q9BZD4,Q13561,Q8WUX9,Q96EE3 4 +Postsynapse organization 0.2580103490322832 0.1792031017132656 0.8577782283365578 1.0 0.9826728411673268 35 P49354,Q9UQB8 2 +Positive regulation of inclusion body assembly 0.3294504181600876 0.1791198756570738 0.8578435758704046 1.0 0.9826728411673268 3 P62195,P49427 2 +Regulation of apoptotic signaling pathway 0.2451238774786508 0.176679179434748 0.8597603959829863 1.0 0.983832429280198 98 Q15233,P51572,O75569,Q9NYF8,P45880,Q9P0J0,Q9NYV6,Q13043,P26583,O60313,P09601,P61254,P62081,Q12846,P14174,Q92974,O00429,P61289,P02545,P62136 20 +Regulation of lipase activity 0.3216101769318547 0.1755804750931967 0.8606235426560354 1.0 0.9841745829870864 12 Q99623,Q9Y263,P50897 3 +Trophectodermal cell differentiation 0.362115327158648 0.1755307213778565 0.8606626333293443 1.0 0.9841745829870864 4 A5YKK6,Q13618,Q6PD62 3 +Meiotic cell cycle checkpoint signaling 0.3276583034647489 0.1750158963411258 0.8610671428927235 1.0 0.9844241428191628 3 Q15645,Q08J23 2 +Positive regulation of immune response 0.239892460852533 0.1748017731507097 0.8612353950181193 1.0 0.9844241428191628 83 Q09472,Q15648,Q15233,Q9BY67,Q9NR50,Q16512,Q96FZ2,Q99623,P46379,Q13177,P15311,P26583,Q12846,Q8WXF1,Q13144,P19174,Q06481,Q9UJZ1,O15400,P09429,Q9UJ41,Q9NUD5 22 +Nucleus localization 0.3079156487855141 0.1735208558603028 0.8622420359255358 1.0 0.9847771428484556 14 P42345,Q96N67,Q9UIS9,Q5SNT2 4 +Mesoderm morphogenesis 0.3320383411693506 0.1735159685844114 0.8622458771431314 1.0 0.9847771428484556 10 P35240 1 +Viral protein processing 0.3412690151879389 0.1730176603124986 0.8626375460463507 1.0 0.9850520779524908 8 Q99873 1 +Regulation of protein deacetylation 0.2845438033128539 0.1717014730064999 0.8636722277221225 1.0 0.9857161521711388 19 Q09472,P49354 2 +Regulation of muscle adaptation 0.2890609097324096 0.1696010316661014 0.8653239111525453 1.0 0.98667143125242 18 Q13464,P25490,Q13485,O75116,Q13555,P02545,P09874,P17252,Q13557,P16615 10 +Hormone biosynthetic process 0.3353844667802443 0.1692531601845651 0.8655975171148813 1.0 0.9866756215047796 9 Q53GQ0,Q15648 2 +Ribosomal subunit export from nucleus 0.3130662245394521 0.1686075671792584 0.8661053280376838 1.0 0.9866756215047796 13 Q96D46,Q9H089,P62841 3 +Autophagosome organization 0.2644942704266134 0.1683386578072739 0.8663168632483511 1.0 0.9866756215047796 28 Q9H2M9,P48426,P04062,Q9Y2L5,P16615 5 +Regulation of calcium ion transmembrane transport 0.278206792571047 0.1670457408360074 0.867334058540703 1.0 0.9876499853492632 22 P21796,P27695 2 +Peptidyl histidine modification 0.3518168150996772 0.1651096595782481 0.868857670117914 1.0 0.988257056740552 6 Q86TU7 1 +Lung associated mesenchyme development 0.2899372947148296 0.1649992491900077 0.8689445730164189 1.0 0.988257056740552 2 Q13308 1 +Angiotensin activated signaling pathway 0.3224232299019028 0.1633947003380222 0.8702076753290033 1.0 0.9885651400428176 3 Q13464 1 +Ribonucleoside triphosphate metabolic process 0.2527639992997974 0.1631377927951891 0.8704099440217636 1.0 0.9885651400428176 38 Q05682,P18859,P06576,O60313,O75964,P56134,P25705,Q9UJZ1 8 +Smooth muscle cell migration 0.3330010823840955 0.1629031404048866 0.8705946981746002 1.0 0.9886029233143276 9 Q9BR76,P27695,Q96N67,Q14344 4 +Regulation of nmda receptor activity 0.2875485219468403 0.1595120195869577 0.8732654893001703 1.0 0.9901350878828636 2 Q15334 1 +Response to platelet derived growth factor 0.3316500665284944 0.1593579208098579 0.8733868895210508 1.0 0.9901350878828636 9 P35241 1 +Negative regulation of erk1 and erk2 cascade 0.2996869772457254 0.1589918798860827 0.8736752713676488 1.0 0.9901350878828636 15 Q12959 1 +Mitochondrial electron transport nadh to ubiquinone 0.2763770843365764 0.158838772110457 0.8737959008472123 1.0 0.9901350878828636 22 O75306,O75380,P51970,O43676 4 +Glial cell migration 0.315918931333788 0.1580076811528242 0.8744507460685633 1.0 0.9902248080589006 12 Q96G23 1 +Retrograde transport endosome to golgi 0.2537326090961861 0.1576887269901062 0.8747020839103643 1.0 0.9903188162663924 36 Q9Y5X3,Q9UNH7,P51151,O60749,P49257,Q8IWJ2,P14373,O15498,Q9P2R3,Q4KMP7,Q8N1B4,Q8IUD2,Q4J6C6 13 +Neurogenesis 0.2208901486318699 0.1565867745415332 0.8755705263434339 1.0 0.9907141354862744 281 Q09472,Q96N67,Q15648,P35240,Q32P28,P55145,Q9NR50,Q13555,Q6P3W7,P50570,P04062,Q14651,P42892,Q9UQB8,Q16512,P35613,Q14108,P00374,Q9Y263,P50542,Q00534,P61160,P26583,P42345,O14744,Q13144,Q96F07,Q96JB5,P27695,Q9NWH9,Q7KZI7,O75306,O94874,Q96PU5,P08670,Q99873,Q92974,Q9HCE1,Q969G3,Q06481,Q9UIS9,Q9UBS4,P18074,P16949,Q9Y2J2,O94887,Q96G23,Q8NCG7,O00264,P09429,P29373,P50897,P27361,Q96N66,Q9BSJ2,P55209,P51608,P63000 58 +Heart process 0.2534036648431006 0.155701236617653 0.8762685223798017 1.0 0.9907141354862744 36 Q96PU5,O00429,Q99996,P16615,Q12959 5 +Positive regulation of ion transmembrane transport 0.2620516701801899 0.1554325337882352 0.8764803375725398 1.0 0.9907141354862744 28 O75323,P35754,P50570,Q4KMQ2,Q99996,P08183,P27695 7 +Middle ear morphogenesis 0.3521310027160006 0.1549584563191613 0.8768540686754231 1.0 0.9907141354862744 4 P54802,O75569 2 +Blastocyst growth 0.3253521368864818 0.1549287227435695 0.8768775095620165 1.0 0.9907141354862744 10 Q9BRT9,O14757 2 +Positive regulation of smoothened signaling pathway 0.3471103923297799 0.1546520857524567 0.8770956054359837 1.0 0.9907141354862744 6 P16435,P35221 2 +Positive regulation of immune effector process 0.2477051575316129 0.1545517480222647 0.877174712293733 1.0 0.9907141354862744 41 P14174,Q9BY67,P09601,Q9UJ41,Q12846,Q06481,Q96FZ2 7 +Negative regulation of amyloid precursor protein catabolic process 0.3326311299262948 0.1513696415749216 0.8796841360072283 1.0 0.9915672907718512 8 P27695,Q13464,Q14254 3 +Sprouting angiogenesis 0.3013098303751843 0.1513267127498448 0.8797179981963048 1.0 0.9915672907718512 14 P09601 1 +Postreplication repair 0.3135055869231743 0.1508035431942181 0.880130691169186 1.0 0.9915672907718512 12 P28340,Q9UBZ9 2 +Endosome organization 0.257158788455486 0.1506231042948558 0.8802730347339878 1.0 0.9915672907718512 30 Q14108,P51159,Q8WUX9 3 +Glycoprotein biosynthetic process 0.2411476044187112 0.1502865386530691 0.8805385529685281 1.0 0.9915672907718512 51 Q10472,Q9Y673,Q7LGA3,O60568,O60502,Q08379,P83436,Q6ZXV5,Q9Y5P6,P33908,Q9H6U8,Q99805,Q2TAA5 13 +Fructose 6 phosphate metabolic process 0.3384375239417764 0.1493472356765616 0.8812796445040834 1.0 0.9915672907718512 7 P17858,P52789 2 +Fc receptor signaling pathway 0.3271457399489601 0.1478235710016313 0.8824820067321719 1.0 0.9915767176195168 9 Q06481,Q16512 2 +Central nervous system development 0.2161939493772931 0.1468841888300154 0.8832234320385419 1.0 0.9919672941657842 184 Q96N67,Q15648,P35240,Q86XL3,Q9BY67,Q9NR50,Q6P3W7,Q9Y2A7,P04062,Q9UQB8,O75569,P24539,P50542,Q00534,Q13043,Q14103,P42345,O14744,Q13144,Q96JB5,P27695,P12277,P00367,P08670,P16104,Q9HCS7,Q06481,Q9UIS9,P51648,P18074,P18859,P14854,P50897,P27361,Q96N66,Q9BSJ2,P61960,P51608 38 +Telomere maintenance in response to dna damage 0.3433874487549279 0.1466659070659455 0.8833957297587691 1.0 0.9919672941657842 6 P27695 1 +Muscle organ morphogenesis 0.3467595750282987 0.144585126222376 0.8850384413800807 1.0 0.9923054860530816 4 Q15648 1 +Cardiac ventricle morphogenesis 0.3467595750282986 0.1445851262223757 0.8850384413800809 1.0 0.9923054860530816 4 Q15648 1 +Ventricular cardiac muscle tissue morphogenesis 0.3467595750282986 0.1445851262223757 0.8850384413800809 1.0 0.9923054860530816 4 Q15648 1 +Cardiac muscle tissue morphogenesis 0.3467595750282986 0.1445851262223757 0.8850384413800809 1.0 0.9923054860530816 4 Q15648 1 +Regulation of immune effector process 0.2413393018980175 0.1443640074997157 0.8852130368956423 1.0 0.9923054860530816 50 P14174,Q9BY67,P09429,P09601,Q9UJ41,Q12846,Q06481,Q16512,Q96FZ2 9 +Fructose 1 6 bisphosphate metabolic process 0.3420029895366294 0.1437607536320596 0.8856893949390976 1.0 0.9924465987933638 6 P17858,Q01813,P09972,P08237,P04075 5 +Regulation of dna dependent dna replication 0.2623123742312371 0.1414182036781004 0.8875395743321577 1.0 0.992481510409228 26 P24941,Q8WVB6,O95251,P54132,Q9UNS1,Q04837,O75844,Q9BRT9,Q9UJZ1 9 +Regulation of cell cycle phase transition 0.2409062828723708 0.141396373911186 0.8875568186920952 1.0 0.992481510409228 127 Q96BK5,Q9UJX5,Q9NZM5,Q6UVJ0,P49959,Q7Z7L1,Q99623,Q96HY6,Q12959,Q96EA4,P15927,P61254,Q6NUQ1,Q14674,Q9UJX4,P51530,Q96JB5,P27695,P24941,P12270,O14757,P16104,Q99459,O95905,Q5JVF3,P19447,Q06481,P61289,Q9UJX2,Q68E01,P35241,P18074,Q92547,P54132,Q9UNS1,Q96RU2,Q01664,P51608,O60885 39 +Regulation of t cell differentiation 0.2943980328003013 0.14105006959389 0.8878303878798448 1.0 0.992481510409228 15 O43290,P09429 2 +Regulation of t cell apoptotic process 0.3115292712066843 0.1409724090481815 0.8878917390296968 1.0 0.992481510409228 3 P78540,P17931 2 +Fibroblast apoptotic process 0.3115292712066809 0.140972409048175 0.8878917390297019 1.0 0.992481510409228 3 Q13618,Q9BZZ5 2 +Negative regulation of mitophagy 0.3115292712066806 0.1409724090481744 0.8878917390297023 1.0 0.992481510409228 3 Q9NQ88,P49815 2 +Negative regulation of neuroblast proliferation 0.3115292712066805 0.1409724090481742 0.8878917390297025 1.0 0.992481510409228 3 P35221,P21359 2 +Response to actinomycin d 0.311529271206676 0.1409724090481655 0.8878917390297094 1.0 0.992481510409228 3 O95251,P62829 2 +Receptor localization to synapse 0.3100975726647333 0.1408842772305245 0.8879613632061398 1.0 0.992481510409228 12 P33176,Q15334,O15400,Q8N8E3,Q12959 5 +Negative regulation of protein tyrosine kinase activity 0.3281878413665058 0.1408331321990323 0.8880017682009627 1.0 0.992481510409228 8 Q99816,Q86XI2,Q9UNH7 3 +Neural retina development 0.340209267563536 0.1400490402314966 0.8886212436635659 1.0 0.9928338017716882 6 P54802,O96019,P51532,P20020,Q8NBN7 5 +Regulation of peptidyl tyrosine phosphorylation 0.2547222734429506 0.1398301263480597 0.8887942097474004 1.0 0.9928570716897528 31 P14174,Q86XI2,P35240,Q9UNH7,P42345,Q9H2J4,Q99816,Q92974 8 +Activation of cysteine type endopeptidase activity 0.343412849117292 0.1383681188037583 0.8899494921270552 1.0 0.9936373628094376 4 Q14790,Q96F07 2 +Regulation of muscle contraction 0.2671329827182224 0.1379476819745701 0.8902817658439375 1.0 0.993668343406454 24 P17252,Q99996,P16615,Q12959 4 +Ameboidal type cell migration 0.2356703253230549 0.1373890488938885 0.8907232866821648 1.0 0.9939911369507196 82 Q7Z739,P25705,Q16512,Q8WTV0,Q4VCS5,Q14185,P42345,P09601,Q9NWH9,Q9NPQ8,Q13464,P19174,P06576,P42785,Q06481,Q5SNT2,P35579,P17252,P67870,O75122,Q9BR76,P09429,P51608,P63000 24 +Regulation of actin filament bundle assembly 0.2566342697662734 0.1368762010739845 0.8911286505537033 1.0 0.9942734781182198 29 P35241,P16949,Q13464,O75122,Q13177,P35240,P42345,Q96AC1,O95429,Q16512,P63167,P63000,Q9NWH9 13 +Regulation of necrotic cell death 0.3026367587745507 0.1361323422595383 0.8917166600911615 1.0 0.9945894588540284 13 P00403,Q92974,P12235,Q14790 4 +Negative regulation of nucleotide metabolic process 0.3417986256348939 0.1354370341603359 0.8922663448468053 1.0 0.9950324959791954 4 P40763,O75376,P09874 3 +Positive regulation of myeloid cell differentiation 0.2726733993037882 0.1349598142084719 0.8926436471874855 1.0 0.9951411499448654 21 Q15648,P26583,O95251,Q99873,P17252 5 +Nuclear membrane reassembly 0.3129363568614655 0.1345603856131728 0.8929594643708845 1.0 0.9951411499448654 11 Q86XL3 1 +Apoptotic signaling pathway 0.2345260748153301 0.1344656839196891 0.8930343448815083 1.0 0.9951411499448654 143 Q09472,Q15233,Q93034,P51572,Q8IXB1,O75569,Q9NYF8,P46379,P45880,Q9H0S4,Q9P0J0,Q9NYV6,Q13043,P26583,O60313,P09601,P61254,P62081,Q12846,Q96A26,Q9NR28,Q2TAL8,P14174,O14737,Q92974,O00429,P61289,P17252,P02545,Q96RU2,P62136 31 +Axis elongation 0.3411934506432413 0.1343494900426903 0.8931262205374007 1.0 0.9951411499448654 4 Q15648 1 +Ire1 mediated unfolded protein response 0.3370725642246931 0.1337001818743196 0.8936396613404847 1.0 0.9955432621898264 6 Q96HY6 1 +Positive regulation of cell substrate adhesion 0.2558908017841577 0.1330423777590017 0.894159865771261 1.0 0.9957601149450992 29 Q14185,P46939,Q00534,Q13043,Q53GQ0,P50570,P63000 7 +Response to ischemia 0.3122754491017891 0.1328058207169809 0.8943469508740227 1.0 0.9957601149450992 11 Q9UNE7,Q15018,Q13501,P46734,P52789,O75116,P30405,O95831,Q9Y4L1,Q9NQ88 10 +Negative regulation of dna dependent dna replication 0.3386006542745478 0.132682287897997 0.8944446512117947 1.0 0.9957601149450992 5 Q9UNS1,P54132 2 +Eye photoreceptor cell differentiation 0.3400059755004437 0.13223344749477 0.8947996461287451 1.0 0.9958484306570522 4 P54802,P40763,Q8NBN7 3 +Positive regulation of response to external stimulus 0.2367441364279862 0.1308518974952625 0.8958924676341016 1.0 0.996521943715723 66 Q09472,P14174,Q15648,Q15233,Q9BY67,P26583,P09429,Q12846,Q8WXF1,O00429,P63000,P17252,Q9NUD5,Q9NWH9 14 +Response to potassium ion 0.3055555555555453 0.1296869357227042 0.8968141190549002 1.0 0.9965709309797404 3 Q9NXV6,Q15334 2 +Cellular response to potassium ion 0.3055555555555453 0.1296869357227042 0.8968141190549002 1.0 0.9965709309797404 3 Q9NXV6,Q15334 2 +Negative regulation of myosin light chain phosphatase activity 0.3049804381915593 0.1286380350492085 0.8976440687125586 1.0 0.9965709309797404 3 Q13464 1 +Negative regulation of bicellular tight junction assembly 0.3049804381915593 0.1286380350492085 0.8976440687125586 1.0 0.9965709309797404 3 Q13464 1 +Meiotic cell cycle process 0.2425390612081014 0.1284926420621802 0.8977591207418902 1.0 0.9965709309797404 45 Q9BZD4,Q08379,O95067,P23258,Q9Y2W6,Q9BTX1 6 +Centriole centriole cohesion 0.3047823826768971 0.1282783457642526 0.8979287010917711 1.0 0.9965709309797404 3 Q9Y496 1 +Regulation of cardiac muscle contraction by calcium ion signaling 0.3190511034231794 0.1282089688843887 0.8979836025054455 1.0 0.9965709309797404 9 P16615 1 +Cell volume homeostasis 0.3361396528819965 0.1281091836655293 0.8980625684230981 1.0 0.9965709309797404 5 P51790 1 +Purine containing compound biosynthetic process 0.2352521725424134 0.1280704662194302 0.898093208089211 1.0 0.9965709309797404 76 P18859,Q9NRG1,P53007,P34897,P06576,P50897,Q8WVC6,O75964,P56134,P25705,Q4G176,Q13126,Q53GQ0,P55263,Q8TB61,Q9UJZ1 16 +Response to thyroxine 0.3043608124253206 0.127515330452142 0.8985325402826834 1.0 0.9965709309797404 3 P48507,O94826 2 +Response to l phenylalanine derivative 0.3043608124253206 0.127515330452142 0.8985325402826834 1.0 0.9965709309797404 3 P48507,O94826 2 +Inflammasome complex assembly 0.3370182252763621 0.1270143823466289 0.8989290152794149 1.0 0.9966718915585222 4 O00571,Q8IXJ6,Q9H6R0 3 +Cell cycle checkpoint signaling 0.2362272432945516 0.126498813753879 0.8993370879913729 1.0 0.9967988014141131 66 Q9NZM5,P49959,Q96EA4,P15927,P61254,Q6NUQ1,P51530,Q96JB5,P24941,P12270,O14757,P16104,Q99459,Q5JVF3,Q68E01,Q92547,P54132,Q96RU2,Q9UNS1 19 +Positive regulation of response to dna damage stimulus 0.2421953354488807 0.1262304861263189 0.8995494799346482 1.0 0.9967988014141131 45 P61160,Q8TDB6,P09429,P16104,Q9UBU8,P51116,Q9NYF8,Q92993,Q9Y4A5 9 +Inflammatory response to antigenic stimulus 0.3088773149804326 0.1239540309604638 0.9013516722549176 1.0 0.9978322329322462 11 P09429 1 +Biological adhesion 0.2177831252122409 0.1227093557325159 0.902337255057824 1.0 0.9978674095997648 177 P35240,Q13017,Q9BY67,Q03001,P50570,Q9UQB8,P35613,Q8WTV0,Q12959,Q00534,Q13043,P15311,Q14254,Q12846,P53582,O43290,P06576,P08865,P17252,P35241,O94887,O75122,P46939,P09429,Q53GQ0,Q92544,P26038,P16615,P63000 29 +Golgi localization 0.3326359832635926 0.1217821269042512 0.9030715692448285 1.0 0.9978674095997648 5 Q9Y678,O14745,P48444,P60953 4 +Negative regulation of b cell activation 0.3007780859473348 0.1211733068781709 0.9035537663269956 1.0 0.9978674095997648 3 Q16512 1 +Regulation of extrinsic apoptotic signaling pathway 0.2466551650691442 0.1206404695396852 0.903975812867876 1.0 0.9978674095997648 37 Q13043,P26583,P09601,Q12846,Q92974,P61289,P02545,P62136 8 +Regulation of membrane permeability 0.2803056761203831 0.120355389912442 0.9042016281441804 1.0 0.9978674095997648 17 P45880 1 +Response to ketone 0.2422448269977391 0.1199267259249119 0.9045411930363316 1.0 0.9978674095997648 41 P04818,Q14103,P04062,Q13126,P26038 5 +Pore complex assembly 0.2969580045655851 0.1196972232442982 0.9047230000754892 1.0 0.9978674095997648 13 P12270,Q9BTX1,Q8N1F7 3 +Trna methylation 0.2801110291518865 0.1196916767589263 0.9047273939425882 1.0 0.9978674095997648 17 Q969Y2,Q96FX7,O60294 3 +Post golgi vesicle mediated transport 0.241087970495764 0.1190016461297173 0.905274051627384 1.0 0.9978674095997648 45 O14828,O75695,Q8IWJ2,P50570,Q9P2R3,O15127,Q4J6C6 7 +Mitotic dna replication checkpoint signaling 0.3322097221644952 0.118929530119398 0.9053311861377242 1.0 0.9978674095997648 4 Q99741,Q92547 2 +Natural killer cell mediated immunity 0.3109411241784373 0.1183553347192447 0.9057861146893388 1.0 0.9978674095997648 10 P51159 1 +Dna dealkylation involved in dna repair 0.2989844683392977 0.1180937628372939 0.9059933654059008 1.0 0.9978674095997648 3 Q8N3C0,P29372 2 +Negative regulation of cell substrate adhesion 0.3063949819090209 0.1176677795288094 0.9063308975897544 1.0 0.9978674095997648 11 O43707,O75122,P35240 3 +Histone h3 k36 trimethylation 0.2986857825567414 0.1175870998816524 0.9063948268318518 1.0 0.9978674095997648 3 Q96ST2,O60885 2 +Mesenchymal cell proliferation 0.3300081193020335 0.1171778800738291 0.906719095292553 1.0 0.9978674095997648 5 P02545,O95747 2 +Positive regulation of intrinsic apoptotic signaling pathway 0.2832412803874902 0.1170336185307112 0.9068334127956508 1.0 0.9978674095997648 16 P61254,P62081,P51572,O00429,O75569,Q9NYF8 6 +Regulation of leukocyte mediated cytotoxicity 0.3282637658233537 0.1168363815253734 0.9069897128878084 1.0 0.9978674095997648 6 Q9BY67 1 +Positive regulation of cell killing 0.3282637658233537 0.1168363815253734 0.9069897128878084 1.0 0.9978674095997648 6 Q9BY67 1 +Mitotic dna replication 0.3060103254599349 0.1167073091686385 0.9070919979831517 1.0 0.9978674095997648 11 P25205,Q14566,O75844,P33991 4 +Proline metabolic process 0.329480192077381 0.1162674799955989 0.9074405579864564 1.0 0.9978674095997648 5 P30038,Q96C36 2 +Regulation of neuron projection arborization 0.3304231353374755 0.1160241861466595 0.9076333734695256 1.0 0.9978674095997648 4 Q9HCE1,Q15334 2 +Pulmonary valve morphogenesis 0.2657509704389262 0.1158069805677647 0.907805518049924 1.0 0.9978674095997648 2 O94813 1 +Metaphase plate congression 0.2480666631982543 0.115282831261247 0.908220946294684 1.0 0.9981118140522288 34 Q9BZD4,Q13561,Q8WUX9,Q96EE3 4 +Negative regulation of cellular amide metabolic process 0.2367785119968881 0.1146437274943583 0.9087275186583216 1.0 0.9981118140522288 90 Q7Z739,P67809,P34897,Q9BPZ3,P00374,Q15024,Q14103,Q00839,P27695,Q10713,P12270,P49458,Q9HCE1,P51116,P04818,Q969T7,Q9NPI6,Q9H074,P31483 19 +Cellular response to corticosteroid stimulus 0.3003276437991163 0.1141182407643917 0.9091440626461356 1.0 0.9981118140522288 12 Q00839,P25705,Q01664 3 +Regulation of atp dependent activity 0.2521051800285244 0.1139649535310641 0.9092655754218112 1.0 0.9981118140522288 29 Q8WXX5,O95433,Q00839,P50570,Q5JTV8,P20585,Q8IXB1,Q04837,Q9Y3Y2,Q9UBS4 10 +Vesicle cytoskeletal trafficking 0.2742077423193907 0.1136985547884308 0.909476758204916 1.0 0.9981118140522288 18 Q9Y4I1,Q9Y496,P33176,O43707,P27695 5 +Negative regulation of cell morphogenesis involved in differentiation 0.2962962962962874 0.1135969530700137 0.9095573028146806 1.0 0.9981118140522288 3 O43707,Q9P258 2 +Organophosphate metabolic process 0.2209999696621169 0.1130161154047292 0.9100177788253448 1.0 0.9984492307690316 261 Q05682,Q09472,O15269,P43490,Q9H773,Q6IAN0,O75964,P54619,P35790,Q99623,Q9BQG2,Q8WTV0,Q12959,Q9NZC3,Q6UWP7,Q9Y263,Q9NRG1,P37268,P13051,O60313,P54646,Q13907,Q8NHP8,Q92643,Q96G03,P55263,Q10713,Q9Y3D8,Q8NFF5,P42356,P12277,P06576,P48426,Q08AM6,P48651,Q8WVC6,P56134,Q4G176,Q96S52,Q9UJZ1,P18859,P04818,P53007,Q969T7,Q86TV6,P50897,Q9UBF8,Q15126,Q53GQ0,Q96DE0,Q96N66,Q01968 52 +Heart valve development 0.3042546214891561 0.112369916619688 0.9105301072867223 1.0 0.9984901282889276 11 Q13485,P42345,Q13464,O94813 4 +Ectoderm development 0.3263650417589834 0.1109944979700695 0.9116207097574986 1.0 0.9986422825437692 5 P35240 1 +Regulation of helicase activity 0.3112808782958656 0.1107377569263358 0.9118243043979704 1.0 0.9986422825437692 9 Q9Y3Y2,Q04837,P20585 3 +Dna integrity checkpoint signaling 0.2388484102297847 0.1075330843816772 0.9143660799410194 1.0 0.9993828486787945 46 Q92547,P24941,P15927,O14757,Q9NZM5,Q6NUQ1,P61254,P16104,Q99459,P54132,Q96RU2,Q9UNS1,P51530,Q96JB5 14 +Organophosphate biosynthetic process 0.2255215813813233 0.1073513557591684 0.914510243894805 1.0 0.9993828486787945 162 Q05682,O15269,P43490,Q6IAN0,O75964,P35790,Q9BQG2,Q6UWP7,Q13907,Q92643,P55263,Q10713,Q9Y3D8,Q8NFF5,P42356,P12277,P06576,P48426,Q08AM6,P48651,Q8WVC6,P56134,Q4G176,Q9UJZ1,P18859,P04818,P53007,Q86TV6,P50897,Q9UBF8,Q15126,Q53GQ0,Q96N66,Q01968 34 +Regulation of protein dephosphorylation 0.2507480324971374 0.1073087602692683 0.91454403498464 1.0 0.9993828486787945 29 P04062 1 +Double strand break repair via nonhomologous end joining 0.2506944223096981 0.1070478325123348 0.9147510328801494 1.0 0.9994416943873856 29 Q8TDB6,P26583,P61160,P09429,Q96FZ2 5 +Negative regulation of cellular component organization 0.2141554105834277 0.1066804568230426 0.9150424873118544 1.0 0.9995927807494412 186 Q09472,Q96BK5,P50570,P04062,P30533,P04350,P45880,P50542,O60313,Q00839,Q9NWH9,P08670,Q9UKS6,P12270,Q9NQP4,O14757,Q5JVF3,Q99471,P61758,P41227,P35241,P16949,Q96G23,Q9BR76,O00264,P09429,O15344,Q9UJ41,Q9UNF0,P63000,Q13813 31 +Regulation of cell killing 0.3171297474080469 0.1055521409936571 0.915937698490215 1.0 1.0 7 Q9BY67 1 +Fatty acid beta oxidation using acyl coa oxidase 0.3170067413055977 0.1053250762884699 0.9161178656376509 1.0 1.0 7 O15254 1 +Calcium ion transmembrane transport 0.241882580170176 0.1037796723554276 0.9173441984602196 1.0 1.0 39 Q93034,P21796,P17252,P16615,P27695,Q9UJZ1,Q9UM00 7 +Cell proliferation involved in heart morphogenesis 0.2900238948625936 0.1036530867996206 0.9174446573425808 1.0 1.0 3 Q06330,Q13485 2 +Positive regulation of cation channel activity 0.3106760213909 0.1033163399599333 0.917711907604573 1.0 1.0 8 P27695 1 +Spliceosomal tri snrnp complex assembly 0.3043145745039736 0.1031606668997391 0.9178354565741328 1.0 1.0 10 O43395,Q15020,Q9Y312,Q8WWY3 4 +Positive regulation of hydrolase activity 0.2383594877520021 0.1022849230413186 0.9185305222081565 1.0 1.0 100 P49354,Q9NR28,Q14997,Q9P0J0,Q9Y263,P07602,P26583,P09429,Q8WU90,Q4KMP7,Q96HY6,Q66K14,Q96A26 13 +Positive regulation of cyclase activity 0.2882317801672537 0.1009516589309829 0.9195888346350636 1.0 1.0 3 P27361,P21359 2 +Negative regulation of hippo signaling 0.2882317801672528 0.1009516589309815 0.9195888346350648 1.0 1.0 3 Q9UGP4,P46734 2 +Negative regulation of dna biosynthetic process 0.2895332429852204 0.09955987708848 0.9206937489459308 1.0 1.0 13 Q00839,Q96BK5,O14757 3 +Positive regulation of intracellular protein transport 0.2335323500269005 0.0984853023395521 0.9215469422537854 1.0 1.0 52 Q9Y282,O14737,P12270,P51572,Q92544,Q9C0E2,P17252,Q9UIS9 8 +Toll like receptor 3 signaling pathway 0.3187761870543648 0.0983793363605844 0.9216310822703984 1.0 1.0 4 Q14254 1 +Cellular response to inorganic substance 0.2408186076267466 0.0976883891607317 0.9221797355638062 1.0 1.0 39 P24941,Q14103,O15111,P54646,P09601,P50570 6 +Regulation of proteolysis 0.2261710569038063 0.0973188002802963 0.9224732264011348 1.0 1.0 159 Q14997,O95376,Q9BXI6,P62191,Q9NZM5,Q8IXJ6,P51572,Q6ZXV5,P04062,Q8NEZ5,Q92530,Q96HY6,Q15392,Q9Y5A7,P46379,Q9Y5K5,Q9P0J0,Q01804,Q13177,P16435,O75116,Q9H2J4,P62081,Q96F07,P46777,O60826,Q9BXK5,Q96JB5,Q96A26,Q9NR28,Q96KC8,Q13464,O14737,P24941,O94874,Q9UKS6,P61289,Q5JVF3,Q06481,P30044,P35579,P17252,Q9NZJ7,P49755,P09429,Q9UBN7,Q01664,P63167,P54725,Q14790,P62913 51 +Histone mrna metabolic process 0.2973259889321099 0.0959993440315041 0.923521093544616 1.0 1.0 11 Q09161 1 +Regulation of cellular response to stress 0.2179802907940063 0.095952588873727 0.9235582273418146 1.0 1.0 174 Q09472,P67809,Q15233,P55145,P51572,Q9NYF8,P00374,Q9UBB9,Q9Y4A5,Q12959,Q92993,Q96HY6,Q00534,P15311,P61160,P15927,P42345,O60313,P61254,Q9UBU8,Q99543,Q9NWH9,P14174,Q8TDB6,O94874,P36507,O14757,P16104,Q99873,P51116,Q96G23,Q9H993,P09429,O15344 34 +Mitotic cell cycle checkpoint signaling 0.2343389183283196 0.095465320763621 0.9239452344426332 1.0 1.0 50 Q92547,P24941,P15927,P12270,O14757,Q9NZM5,P61254,Q6NUQ1,P54132,P49959,Q5JVF3,Q96JB5,Q68E01,Q96EA4 14 +Chromosome localization 0.240355789982722 0.0950627928501837 0.9242649511982132 1.0 1.0 39 Q9BZD4,Q96BK5,P61160,Q8WUX9,Q00839,Q96EE3,Q9UJX2,Q9BW19,Q13561 9 +Actin filament network formation 0.3162231902381743 0.0948081981704492 0.9244671750093278 1.0 1.0 4 Q14651 1 +Regulation of protein localization 0.219074417305183 0.0944558539850097 0.9247470490170432 1.0 1.0 218 P35580,Q96BK5,O95376,P35240,Q32P28,P49257,P51572,Q14651,Q96HY6,Q12959,Q9Y282,P15311,P54646,Q16850,Q12846,Q96JB5,Q10713,Q96KC8,O14737,P00367,Q8TDB6,Q96PU5,P12270,Q8IWJ2,O00429,P17252,Q9UIS9,P35241,Q9C0E2,Q96EZ8,P26038,O00264,Q92544,P61960,P53985 35 +Response to hepatocyte growth factor 0.3099989807515314 0.0928739842442972 0.9260036739634124 1.0 1.0 7 Q06481 1 +Relaxation of cardiac muscle 0.3146100985957535 0.0926060001827553 0.9262165767793092 1.0 1.0 4 Q13557,P05023,P05026 3 +Positive regulation of ossification 0.313901345291489 0.0923780775082161 0.9263976565545328 1.0 1.0 6 Q4KMQ2,Q6KC79,O95747,P20020,Q06124 5 +Regulation of receptor mediated endocytosis 0.2564838452416531 0.0922206721372178 0.9265227140402944 1.0 1.0 24 P50897,Q6P3W7,Q9UJ41,P50570,P63000 5 +Positive regulation of bone mineralization 0.3137137735285253 0.0914003774456917 0.927174461847887 1.0 1.0 4 Q4KMQ2,O95747,P20020 3 +Positive regulation of biomineralization 0.3137137735285253 0.0914003774456917 0.927174461847887 1.0 1.0 4 Q4KMQ2,O95747,P20020 3 +Protein localization to membrane raft 0.313285647054187 0.0906861089801646 0.9277420085747292 1.0 1.0 5 Q14254 1 +Blood vessel morphogenesis 0.2306141376563316 0.0893260643951538 0.9288227804718416 1.0 1.0 82 Q13043,Q9BXJ9,P09601,Q9H2J4,P42785,Q96PU8,P35613 7 +Entrainment of circadian clock 0.3118086696562107 0.0891250200587388 0.928982553384294 1.0 1.0 6 P29992,P62136,P62140,Q9BWF3,Q13330 5 +Regulation of exit from mitosis 0.3117421381579328 0.0890228780549461 0.9290637282449868 1.0 1.0 6 Q9UJX2,Q99623 2 +Regulation of response to oxidative stress 0.2576123103215164 0.0887696614156931 0.9292649691605614 1.0 1.0 23 P00374 1 +Positive regulation of nucleotide metabolic process 0.3119027814343135 0.0887096012586258 0.929312701921002 1.0 1.0 5 P00403,P54646 2 +Positive regulation of striated muscle cell apoptotic process 0.3117154811715416 0.0884443728558574 0.9295234950149842 1.0 1.0 5 Q13485,Q13557,Q9NQ88,P17655 4 +Photoperiodism 0.3117154811715399 0.0884443728558548 0.9295234950149862 1.0 1.0 5 Q9BWF3,P62136,P62140,Q13330 4 +Endoplasmic reticulum unfolded protein response 0.2616599028570427 0.0879244852292944 0.9299366955676938 1.0 1.0 20 Q09472,Q2TAL8,Q96JB5,Q96HY6 4 +Positive regulation of phagocytosis 0.2966700572814433 0.0869074537816551 0.9307450746794989 1.0 1.0 10 Q06481,P51159 2 +Vesicle mediated transport 0.217031373946365 0.0846412431824648 0.9325466093791308 1.0 1.0 366 P24390,Q15075,Q8WUX9,Q6P3W7,P51572,P50570,P55735,P30533,Q14108,O15127,Q8WTV0,Q15019,Q7Z392,Q9Y282,Q9Y263,P15311,P09601,O95070,P27695,Q4J6C6,O14828,O75695,Q8TDB6,Q96PU5,P36507,Q9UKS6,Q8IWJ2,O00429,Q9UPT5,Q06481,Q4KMP7,Q9Y2L5,Q9P2W9,P35241,O43760,Q08379,Q8TBA6,Q9UNH7,P09429,P51159,P50897,Q9UBF8,Q9UJ41,Q92544,Q9P2R3,Q9Y3B3,Q9UNF0,Q15036,Q6NYC1,P63000,P26038,P16615,Q8IUD2 53 +Regulation of cellular response to heat 0.2981982217182927 0.0843323482625306 0.9327921938066036 1.0 1.0 9 Q09472,P42345 2 +Signal transduction in response to dna damage 0.2295954390137877 0.0830682952665788 0.933797235404239 1.0 1.0 57 P14174,Q92547,P24941,P15927,O14757,Q9NZM5,P61254,Q6NUQ1,P16104,Q99459,P54132,Q96RU2,Q01664,Q96JB5,O75844,Q92993 16 +Regulation of heart rate 0.2779777081525443 0.0830671028649524 0.9337981835263014 1.0 1.0 14 Q99996,P16615 2 +Protein heterotetramerization 0.2996639294488801 0.0829988544757741 0.9338524504684532 1.0 1.0 8 Q9Y285 1 +Spindle elongation 0.3061285500747522 0.0806869804493177 0.9356908911507936 1.0 1.0 6 O43663,O95239,Q9H0H5,Q14980,P30153 5 +Cellular response to gonadotropin stimulus 0.3044517478338785 0.079686536129321 0.9364865680103692 1.0 1.0 4 P16435,P48507,P20248 3 +Response to gonadotropin 0.3044517478338785 0.079686536129321 0.9364865680103692 1.0 1.0 4 P16435,P48507,P20248 3 +Brainstem development 0.2709080047789626 0.0779390647398019 0.9378765247372404 1.0 1.0 3 Q13485,P31939 2 +Cartilage development involved in endochondral bone morphogenesis 0.3022938278568018 0.0771491608655449 0.9385048847913224 1.0 1.0 4 P16435 1 +Regulation of dna strand elongation 0.2998693780079651 0.0765433275941313 0.9389868446250488 1.0 1.0 7 Q96EZ8 1 +Mrna transport 0.2294721654643434 0.0764264079551235 0.9390798605330232 1.0 1.0 76 Q86U42,Q09161,O60318,P12270,Q9UPR3,P55735,Q96PU8,Q5JVF3,Q96EE3,Q9BTX1 10 +Regulation of fibroblast migration 0.2957263535455057 0.0763401191265897 0.9391485085047108 1.0 1.0 8 Q06481 1 +Positive regulation of dna templated transcription initiation 0.27495446229878 0.0754047102904551 0.9398927116118678 1.0 1.0 14 Q15648,Q9Y2X0,O75448 3 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.299059413644338 0.0753214227980688 0.939958976968594 1.0 1.0 7 Q09472 1 +Collagen fibril organization 0.2932354971330563 0.0752972555701473 0.939978205023322 1.0 1.0 9 O60568 1 +Positive regulation of supramolecular fiber organization 0.2319721479674067 0.0750529532047104 0.9401725800961184 1.0 1.0 49 P35240,P30622,P42345,Q9Y295,P14373,Q9UQB8,Q16512,P63000,Q99996,P51608,Q9NWH9,Q12959 12 +Regulation of phosphatidylinositol 3 kinase activity 0.2673237753882839 0.0738549558781681 0.941125797915464 1.0 1.0 3 Q99570,P60953 2 +Semi lunar valve development 0.3011751582531591 0.0737898083275085 0.941177636693638 1.0 1.0 6 Q13464,O94813 2 +Cellular component morphogenesis 0.2300099296346557 0.0733021036522048 0.941565717733245 1.0 1.0 141 Q96N67,Q9Y2A7,P50570,P42892,Q9UQB8,Q16512,P35613,Q04837,Q8IYB8,Q9Y263,Q13177,P61160,Q96F07,Q9Y5P4,Q9Y2S7,Q9NZM3,Q7KZI7,Q13464,A0MZ66,Q96PU5,O60749,O00429,Q9HCE1,Q06481,P18074,P16949,Q9Y2J2,O75122,Q9H2U1,Q9BR76,O00264,P29373,Q9UNF0,P63000 34 +Pulmonary valve development 0.2658303464754957 0.0722189363577927 0.9424276754873516 1.0 1.0 3 Q06330,O94813 2 +Cellular transition metal ion homeostasis 0.2560614222063422 0.0721921659635811 0.9424489795632216 1.0 1.0 21 Q9Y487,P09601 2 +Pyrimidine nucleobase biosynthetic process 0.2968500050266037 0.0720506673018851 0.9425615859186024 1.0 1.0 7 Q05682 1 +Cytoplasmic sequestering of nf kappab 0.2966835972512636 0.0708830035949566 0.9434908705125792 1.0 1.0 4 O60826,Q9UNN5,O75832 3 +Negative regulation of cell cycle phase transition 0.2285453496489304 0.0707552880928369 0.9435925175222222 1.0 1.0 77 Q96BK5,Q9NZM5,P49959,Q7Z7L1,Q96EA4,Q12959,P15927,P61254,Q6NUQ1,P51530,Q96JB5,P24941,P12270,O14757,P16104,Q99459,Q5JVF3,Q68E01,Q92547,P54132,Q9UNS1,Q96RU2 22 +Calcium ion transport 0.2278575878585106 0.0707240906153233 0.9436173473046774 1.0 1.0 57 O75323,Q93034,Q9UKS6,Q13555,P14373,Q4KMQ2,P21796,O00429,P17252,O75844,P16615,P27695,Q9UJZ1,Q9UM00 14 +Regulation of glycoprotein metabolic process 0.2905445840813802 0.0706212119981996 0.9436992278281426 1.0 1.0 9 Q9UHD1,Q08379,Q9NY61,Q9H0U4,P62820,O14734,Q92542,Q99805 8 +Regulation of response to stress 0.2176778153249807 0.0700793963152807 0.9441304657357944 1.0 1.0 272 Q7Z739,P67809,Q09472,Q15648,Q15233,Q9BY67,P55145,Q3LXA3,P51572,P04062,Q16512,P08183,Q9NYF8,Q9UBB9,P00374,Q9Y4A5,Q12959,Q92993,Q96HY6,Q00534,P15311,P26583,P15927,P42345,O60313,P61160,P61254,Q9UBU8,Q8WXF1,Q15366,Q8TAT6,Q9NWH9,P14174,Q8TDB6,P36507,O14757,P16104,Q99873,P51116,Q06481,Q14166,O75122,Q96G23,Q9UNH7,Q9H993,Q8NCG7,P09429,O15344,Q9UJ41,Q9NUD5 50 +Mrna export from nucleus 0.2358072624681928 0.0700450773590793 0.9441577811768638 1.0 1.0 39 Q86U42,Q09161,O60318,P12270,Q9UPR3,Q5JVF3 6 +Transferrin transport 0.2954885688397813 0.069609023297576 0.944504854811476 1.0 1.0 4 P50570 1 +Ventricular septum morphogenesis 0.2964579456934142 0.0687844603836738 0.9451611876061304 1.0 1.0 5 Q13485 1 +Necrotic cell death 0.2566534978595939 0.0686398980923217 0.9452762596569896 1.0 1.0 19 O00429 1 +Protein heterooligomerization 0.2890734048302426 0.0681305230540422 0.9456817329166352 1.0 1.0 9 Q9Y285 1 +Cellular amide metabolic process 0.2253764930060926 0.0681204617218871 0.9456897420910212 1.0 1.0 471 O15269,P34897,Q9H2D1,P23381,Q567V2,P04062,Q8N4J0,P00374,Q15024,Q9ULC4,Q9H7Z7,P42345,P57772,P61254,Q16540,Q96PU8,P53582,Q09161,P08670,Q4G176,P62899,O95900,P53007,Q969T7,Q96G23,Q8TCT9,P50897,P62753,Q15126,Q7Z7H8,Q9Y3D3,Q7Z739,P67809,P62841,P46199,Q9HA77,P50914,P27695,Q10713,Q96KC8,P41567,Q15650,P62917,P51116,Q9BW92,P46782,P04818,P61513,P55010,P31483,Q8N5C6,P67812,Q9BPZ3,Q96EY7,O75879,Q9BTE6,Q8WU90,P25398,Q9HCE1,P29692,Q9NPI6,P27635,P00390,P20042,Q9Y285,P42892,Q14103,P62081,Q00839,Q13144,Q9Y5P4,P08865,P12270,P49458,Q02543,Q53GQ0,Q92552,Q9H074,Q9Y295 79 +Nuclear envelope organization 0.2421638491110535 0.0675067630634698 0.9461782781634742 1.0 1.0 29 P20700,Q86XL3,Q8WUX9,Q9UNZ2,Q5JTV8,P02545,P17252,Q8N1F7 8 +Very long chain fatty acid metabolic process 0.2865305644757547 0.0674446566251296 0.9462277192516052 1.0 1.0 10 P50542,P28288 2 +Microtubule cytoskeleton organization involved in mitosis 0.2281517446552881 0.0673650501636379 0.9462910918904311 1.0 1.0 77 Q9UQE7,Q8WUX9,Q9UNZ2,P23258,O00139,Q9NVM9,Q9BZD4,Q00839,Q9Y2S7,Q13561,O43663,P12270,Q9BW19,Q9NS87,P16949,Q08379,O75122,P51608,Q9Y295 19 +Regulation of organelle assembly 0.2288268896459739 0.0670542817643864 0.9465384898003072 1.0 1.0 66 P35241,Q16181,P15311,P48426,P12270,Q8WUX9,P54646,Q9Y295,Q00839,P50570,Q6UVJ0,Q99816,Q4KMP7,Q9P2W9,P26038,P27695,Q66K14,Q9NS87 18 +Pyrimidine ribonucleoside diphosphate metabolic process 0.2922019719151406 0.0662133555605734 0.9472079639098884 1.0 1.0 4 Q05682,P30085,P11172 3 +Negative regulation of cell growth 0.2399719781427454 0.0659392465057574 0.9474261943660872 1.0 1.0 31 Q9P0J0 1 +Negative regulation of signaling 0.2166920111642338 0.0658957168312077 0.9474608506467446 1.0 1.0 213 Q7Z739,P35240,Q15233,Q6P3W7,Q3LXA3,P50570,P04062,P30533,O95630,Q96HY6,Q12959,P45880,Q9P0J0,Q9NYV6,Q13043,P15311,P26583,O60313,P09601,P54646,Q8TAT6,Q9H3F6,Q96JB5,Q9NWH9,Q10713,P14174,P61289,Q9NWT6,Q14166,P17252,P16949,Q9UNH7,Q9UJ41 33 +Positive regulation of atp metabolic process 0.2949198982397246 0.065681524505074 0.9476313819549684 1.0 1.0 6 P00403,P54646 2 +Brown fat cell differentiation 0.2888932631644708 0.0655297480233659 0.9477522217330612 1.0 1.0 8 Q6IAN0 1 +Regulation of cellular component size 0.2284223151508693 0.0648510933502048 0.9482925604245775 1.0 1.0 83 Q9Y2A7,P50570,Q14651,Q9UQB8,Q12959,P51790,P52907,P15311,P42345,P47755,Q4KMQ2,Q96F07,Q01082,P35241,P29373,P62136,P59998,P26038,P63000,Q13813 20 +Morphogenesis of an endothelium 0.2901105467582845 0.0641340013714353 0.9488635283850704 1.0 1.0 4 Q06330,P67870,P61586 3 +Adherens junction assembly 0.2901105467582842 0.064134001371435 0.9488635283850706 1.0 1.0 4 P18206,Q9BTW9,Q13177 3 +Pyrimidine nucleoside diphosphate biosynthetic process 0.292289300657494 0.0640636341681034 0.9489195580684572 1.0 1.0 5 Q05682,P23919,P30085,P11172 4 +Pyrimidine nucleoside diphosphate metabolic process 0.292289300657494 0.0640636341681034 0.9489195580684572 1.0 1.0 5 Q05682,P23919,P30085,P11172 4 +Dna strand elongation 0.2509946031371745 0.0640388089594437 0.9489393251297816 1.0 1.0 23 P25490,Q96EZ8,P49959,P09884,Q92878,P33991,P51530,Q9Y5K5,Q07864,P25205 10 +Positive regulation of rna splicing 0.2531990495947095 0.0625122698423068 0.9501548911297846 1.0 1.0 21 Q8WVV9,Q09161 2 +Peptidyl threonine dephosphorylation 0.289001793185886 0.0605304162855418 0.9517331915632664 1.0 1.0 5 P49593,P62136,Q96HS1,P53041 4 +Positive regulation of osteoblast differentiation 0.290284005979081 0.0600958504598144 0.952079294845252 1.0 1.0 6 Q13418,Q9NR12,Q96AC1,P20248,O00299 5 +Cardiac conduction 0.2535738848848329 0.0590625980579471 0.9529022490369768 1.0 1.0 19 Q99996,P16615 2 +Regulation of hematopoietic progenitor cell differentiation 0.2815001857620802 0.0586633965595674 0.95322021441808 1.0 1.0 10 Q96PZ0,Q00534 2 +Glutamine family amino acid biosynthetic process 0.2866841591555946 0.0581578467666557 0.9536228972652095 1.0 1.0 7 P00367,Q96C36 2 +Positive regulation of vascular associated smooth muscle cell proliferation 0.2830805014073017 0.0575972285394469 0.9540694573151288 1.0 1.0 4 O95140 1 +Body morphogenesis 0.2824224093080564 0.0574446949462656 0.9541909603414926 1.0 1.0 9 Q09472 1 +Establishment of mitochondrion localization 0.2800985381192036 0.0563184289387347 0.9550881379637448 1.0 1.0 10 P27695 1 +Neuron projection organization 0.246762586930316 0.05495960576298 0.9561706450572218 1.0 1.0 24 Q14651,Q9UQB8 2 +Meiosis i cell cycle process 0.2467518822213747 0.0549209890062862 0.9562014103046494 1.0 1.0 24 O95067 1 +Regulation of dephosphorylation 0.2348835473620369 0.0545912787713349 0.9564640869311344 1.0 1.0 36 Q13464,P17931,Q86XL3,P42345,Q12972,Q9UPR3,P04062,O95429,Q15257,P63167,Q96JB5,P67870,Q13614 13 +Very long chain fatty acid catabolic process 0.2790558709291822 0.0541599031518475 0.956807766420011 1.0 1.0 4 O14975,Q15067,P28288 3 +Regulation of actin filament organization 0.2274026726206525 0.0535393319050055 0.957302193244052 1.0 1.0 70 P35240,Q9Y2A7,Q9UQB8,Q16512,Q12959,P52907,Q13177,P42345,P47755,O95429,Q96F07,Q9NWH9,Q13464,Q01082,Q96AC1,Q92747,Q9NYL9,P35241,P16949,O75122,Q9BR76,O94813,P14373,Q9UEY8,P59998,P60983,P63000,Q13813 28 +Neural tube formation 0.2441242187028895 0.0523798519505711 0.9582260278897377 1.0 1.0 25 P17252,O60313,Q13043 3 +Negative regulation of jnk cascade 0.2822122571001593 0.0512037289298917 0.9591631804881762 1.0 1.0 6 P31689,P43034,P51452,O75376,Q53EL6 5 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.2260379200102297 0.0510795384824531 0.9592621406305886 1.0 1.0 53 Q09472,P49354,Q01082,Q9UNH7,Q9GZN8,Q13485,Q96AC1,P08670,P50570,P27361,Q06481,P09874,Q53EL6,P67870,Q8N1F7 15 +Protein localization to microtubule 0.2781474166453655 0.0510655077302019 0.9592733209602728 1.0 1.0 9 O15344 1 +Oocyte maturation 0.2788404064554641 0.0506313216324941 0.9596193037723126 1.0 1.0 5 Q15645,P30153,Q8IXJ6,O14965 4 +Epiboly 0.2777761863039549 0.0499111922722288 0.9601931582775948 1.0 1.0 8 P42345,Q96AC1,O75122 3 +Cell cycle dna replication 0.2491774569904513 0.0494865509297497 0.9605315548718868 1.0 1.0 21 P54132,P51530,Q14566,O75844,P25205 5 +Regulation of actin filament length 0.2295846726299597 0.0475924963687972 0.962041012284961 1.0 1.0 43 P35241,P52907,Q01082,P42345,P47755,Q92747,Q9Y2A7,Q9UEY8,Q9UQB8,O95429,Q96F07,P59998,Q9NYL9,Q13813,Q12959 15 +Regulation of ras protein signal transduction 0.2335697489298147 0.0463755558629349 0.9630109191411362 1.0 1.0 35 P35241,P16949,Q9UJ41,P50570,O95630,Q9H3F6,P63000 7 +Collateral sprouting 0.2719877433216753 0.0447883883037177 0.9642759805971894 1.0 1.0 5 P29373 1 +Perk mediated unfolded protein response 0.2662705093744684 0.0446266975884671 0.9644048622559548 1.0 1.0 4 Q2TAL8 1 +Integrated stress response signaling 0.2662705093744684 0.0446266975884671 0.9644048622559548 1.0 1.0 4 Q2TAL8 1 +Regulation of ligase activity 0.2715102635246713 0.044405193575094 0.9645814218599396 1.0 1.0 5 Q9UBB9 1 +Sodium ion transport 0.238910919724543 0.0439824034206027 0.9649184303291718 1.0 1.0 27 P46939,Q96PU5,P35754,Q6P4Q7,P50570,Q12959 6 +Regulation of cell size 0.2288373621536246 0.0435821503663756 0.9652374801215148 1.0 1.0 43 P35241,P51790,P15311,P29373,P42345,P50570,Q4KMQ2,P26038,P63000 9 +Positive regulation of muscle hypertrophy 0.2725155488530588 0.0432324833762492 0.9655162112972422 1.0 1.0 9 P17252,O75116,Q13464,P09874 4 +Regulation of establishment or maintenance of cell polarity 0.2712241947327513 0.042482678041356 0.9661139202038728 1.0 1.0 10 Q14254,Q13464,Q15334,A0MZ66 4 +Response to oxygen containing compound 0.2114018465747287 0.0422790161994491 0.9662762729735404 1.0 1.0 298 P43490,P04062,P33908,Q9UQB8,P35613,Q99996,Q8WTV0,P00374,Q9P0J0,Q9Y263,P15311,O15111,P09601,Q13126,P27695,P14174,P08670,Q06481,Q9BSK2,P04818,P09429,Q15126,Q9NS86 23 +Mammary gland epithelium development 0.2720025154813514 0.0413093306685945 0.9670492946233556 1.0 1.0 7 Q15648 1 +Transcytosis 0.2717311078417505 0.0411652161071236 0.9671641836801492 1.0 1.0 6 P30533 1 +Neuron migration 0.2386728567376935 0.0401218917211134 0.9679959487824203 1.0 1.0 26 Q9Y263,P50542,Q9BSJ2,Q9UIS9,P63000,Q7KZI7 6 +Cellular response to steroid hormone stimulus 0.2241243122918335 0.0400705232507382 0.9680369019582749 1.0 1.0 60 Q09472,Q15648,Q13185,P25705,Q16512,Q99623,Q96HY6,Q00839,P09874,O15173,O94874,Q15650,Q9P253,Q9GZZ9,P51532,Q9UBN7,Q01664,P61960,Q9Y4C1,Q9NUQ7 20 +Dna synthesis involved in dna repair 0.2590763475841452 0.0396257108498311 0.9683915292392528 1.0 1.0 14 P28340,Q9UBZ9,P09884,Q07864,P40938,Q9Y2S7 6 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.2626629867211742 0.0395604443727265 0.9684435635528736 1.0 1.0 13 Q96A26 1 +Regulation of leukocyte mediated immunity 0.2327393553763263 0.0392950409963827 0.9686551602761732 1.0 1.0 34 Q9BY67,P09429,P09601,Q9UJ41,Q12846,Q96FZ2 6 +Regulation of production of small rna involved in gene silencing by rna 0.2689644164695434 0.039195646131976 0.9687344048542396 1.0 1.0 8 P36507 1 +Mitotic sister chromatid cohesion 0.2624279231214735 0.0391234893496078 0.9687919335106367 1.0 1.0 13 P41227 1 +Cellular response to alkaloid 0.269789484178118 0.0390827060011755 0.968824449046205 1.0 1.0 7 O14757 1 +Neuron projection arborization 0.2681338387287394 0.0374683156041781 0.970111602884332 1.0 1.0 7 Q9HCE1,Q13464,Q15334 3 +Cell growth 0.2329011161690559 0.0369068503899761 0.9705592776488798 1.0 1.0 109 Q6PJG6,Q9P0J0,Q09161,Q96PU5,P50897,Q5BJF2,Q9BTE7,Q9BSK2 8 +Spindle midzone assembly 0.2663677130044917 0.0366512784254398 0.9707630567004648 1.0 1.0 6 Q9NQS7,O43663,O95239,Q9H0H5,Q02241 5 +Camera type eye development 0.2292517564754163 0.0365551366342287 0.9708397153806354 1.0 1.0 39 Q15293,P25490,P35240,P08670,Q6NYC1,Q99471,Q12959 7 +Cellular response to vitamin d 0.2603108188882181 0.0362657351160452 0.9710704713734568 1.0 1.0 5 O15164,P20020,Q15648,Q13573 4 +Regulation of execution phase of apoptosis 0.2602525524806692 0.0362274942303009 0.9711009631488936 1.0 1.0 5 P63167,Q13177 2 +Positive regulation of mitotic cell cycle phase transition 0.2297768548877912 0.0355645039261093 0.9716296121690122 1.0 1.0 38 P35241,O00571,Q9UJX5,Q13618,Q99741,Q7L2J0,Q14674,Q6UVJ0,Q9UJX2,Q9UJX4,Q9NYL9,Q99623,P51608,P27695,O60885 15 +Regulation of dna replication 0.2227753208591849 0.0354923985137329 0.9716871076653872 1.0 1.0 55 Q9UQE7,P24941,P25490,Q96EZ8,Q04837,P51530,Q9BRT9,Q9UJZ1,Q9UBD5 9 +Regulation of protein serine threonine kinase activity 0.2249588883468589 0.0352683901063241 0.971865728683361 1.0 1.0 69 P04062,O95067,Q13043 3 +Positive regulation of membrane potential 0.2630621972798008 0.0340688042271683 0.9728222846577386 1.0 1.0 6 P35754,Q9UJZ1,Q8IWA4 3 +Negative regulation of cell substrate junction organization 0.256126718469807 0.0336223890104517 0.9731782685114104 1.0 1.0 5 P63167,Q9P258,O75122,Q9ULV4 4 +Regulation of cell substrate adhesion 0.2260644726897062 0.0334920956608264 0.9732821690463064 1.0 1.0 47 Q14185,Q13464,O75122,Q00534,Q13043,P35240,P46939,O43707,O75116,Q96AC1,Q13630,P50570,P18206,Q53GQ0,Q92766,P63167,P63000,Q9Y2S7 18 +Regulation of oligodendrocyte differentiation 0.263022236209039 0.0327555512568928 0.9738695241334988 1.0 1.0 7 P42345 1 +Response to vitamin d 0.2603886397608453 0.0320876817480383 0.9744021268940936 1.0 1.0 6 Q15648,Q14258,O15164,P20020,Q13573 5 +Cellular response to vitamin 0.2603886397608456 0.0320876817480383 0.9744021268940936 1.0 1.0 6 Q96C86,Q15648,O15164,P20020,Q13573 5 +Positive regulation of stress fiber assembly 0.2532410757493734 0.0309068939682588 0.9753437919594812 1.0 1.0 15 P35240,Q96AC1,P42345,O95429,Q16512,P63000 6 +Response to oxygen levels 0.2244361402785819 0.0307338674801604 0.9754817815693266 1.0 1.0 71 Q09472,Q96A26,P30519,Q8N511,P51608,P42345,Q9NZM5,P09601,Q92544,P02545,Q9NWT6,Q99623,Q9Y487,O75306 14 +Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus 0.2575321729857843 0.0300744692067245 0.9760076621398794 1.0 1.0 6 Q09472 1 +Peptidyl asparagine modification 0.2614474271068788 0.0300097885921563 0.976059246520152 1.0 1.0 11 P04844,Q9Y673,Q9NWT6 3 +Small rna loading onto risc 0.2492528392109934 0.0297148093848626 0.9762945009562848 1.0 1.0 5 O75569,O94992,Q08211,Q9UPY3 4 +Homologous chromosome segregation 0.2610942580239088 0.0295109141112034 0.9764571145315664 1.0 1.0 11 P46379,Q14674,P49959,P53350,Q9BTX1 5 +Pattern recognition receptor signaling pathway 0.229031952491651 0.0258874267078061 0.9793471287208038 1.0 1.0 35 Q14254,P09429,Q9NZM5,Q9H078,Q3LXA3,Q9NUD5,Q8TAT6,Q06481,Q99623 9 +Regulation of cell cycle g2 m phase transition 0.2252597035953757 0.025835956957767 0.9793881819086656 1.0 1.0 41 Q96BK5,Q92547,P24941,O14757,Q9NZM5,Q6NUQ1,P54132,Q96JB5,P51608,Q68E01,O60885 11 +Blastocyst development 0.2286416669848005 0.0241889846189813 0.980701864561647 1.0 1.0 35 O43678,O14757,Q13503,Q9HCS7,Q9BRT9,Q8IWS0 6 +Aerobic respiration 0.2242089949815645 0.024039735738135 0.9808209133206808 1.0 1.0 84 P18859,O43678,O75323,P34897,P51970,P06576,O75380,O43676,P22695,O75964,Q9UDW1,P56134,Q9BSK2,O75390,Q9UJZ1,O75306 16 +Positive regulation of transcription by rna polymerase iii 0.2567230051805043 0.023488379580463 0.9812607076806574 1.0 1.0 10 P55199 1 +Proteasomal protein catabolic process 0.2177300739660831 0.0234871775794366 0.9812616664742104 1.0 1.0 165 Q14997,O95376,Q9UJX5,Q93034,Q9NZM5,Q9UNZ2,P51572,Q6ZXV5,P04062,Q7L5D6,Q8IXB1,P33908,Q96CS3,Q8NEZ5,Q92993,Q96HY6,P46379,Q9Y263,P55036,Q15366,Q8WW12,Q8TAT6,Q9UJX4,Q9H1A4,Q9H3F6,Q9NXV2,P24941,O94874,Q96PU5,Q15650,P61289,P17252,Q9UJX2,P49721,Q8TCT9,Q96A33,P54725 37 +Protein polyubiquitination 0.2203844498235718 0.0233866447435147 0.9813418580446218 1.0 1.0 56 Q9Y263,O95376,Q9UJX5,Q5VTR2,Q8TDB6,Q96PU5,Q9UJX4,Q9H1A4,Q9UJX2,Q8NEZ5 10 +Lung morphogenesis 0.2549289711070729 0.0227455070866591 0.981853275807182 1.0 1.0 9 O60568 1 +Head morphogenesis 0.2447357649156583 0.0222883404866086 0.9822179495172358 1.0 1.0 6 Q09472 1 +Cerebral cortex development 0.2353568015771805 0.0217060568047633 0.9826824322806276 1.0 1.0 25 Q96N66,Q9HCS7,P50542 3 +Nuclear migration 0.251950763352277 0.0211397036444214 0.9831342130352104 1.0 1.0 13 Q9UIS9,Q96N67,Q5SNT2 3 +Mitotic dna integrity checkpoint signaling 0.229306760764864 0.0204047840147386 0.983720467553988 1.0 1.0 31 Q92547,P24941,P15927,O14757,Q9NZM5,Q6NUQ1,P61254,P54132,Q96JB5 9 +Rna interference 0.2494765180975133 0.0203135909442072 0.9837932140188516 1.0 1.0 8 Q9HAV4,Q92879,O94992,Q08211,O75569,Q15631,Q9UPY3 7 +Leukocyte mediated cytotoxicity 0.2474528071626586 0.0196217911224719 0.984345080376856 1.0 1.0 15 Q9BY67,O15400,P51159 3 +Cellular response to interferon gamma 0.2373132799658078 0.019125291060204 0.9847411557696352 1.0 1.0 23 O60506,Q15648,P61160,P08670,Q12846 5 +Mrna methylation 0.2443181818181818 0.0187607466909274 0.9850319679100992 1.0 1.0 7 Q5T200,Q7L0Y3,Q08J23,Q15007,Q8N1G2,Q96FX7 6 +Regulation of erbb signaling pathway 0.2502316122534676 0.0184621503576079 0.9852701720546172 1.0 1.0 13 P27695 1 +Kidney morphogenesis 0.2503114229940832 0.0183029647622606 0.9853971623253244 1.0 1.0 9 Q13485,O75844,Q13418,Q12959 4 +Regulation of calcineurin mediated signaling 0.2434210526315797 0.0182078307147239 0.9854730556658882 1.0 1.0 7 Q9UHD1,P42345,O94916,Q13164,P26599,P49841 6 +External encapsulating structure organization 0.2356379026069399 0.017725745114163 0.9858576422415032 1.0 1.0 24 P18074,O75122,O60568,O75718,O75955,Q53GQ0,Q8IYI6,Q9NPQ8 8 +Cytoskeleton dependent cytokinesis 0.2222498608629862 0.0175614575617059 0.985988704341808 1.0 1.0 49 Q6DKK2,Q16181,P35580,P16949,Q13464,Q01082,P61160,Q8WUX9,Q14141,Q14674,O95630,O95235,Q9Y2S7,Q15019 14 +Negative regulation of cell junction assembly 0.2494784871304833 0.0175405663456919 0.9860053705534106 1.0 1.0 9 P63167,Q13464,O75122 3 +Negative regulation of cell cycle process 0.224400467472832 0.0175217325423964 0.9860203954452196 1.0 1.0 86 Q96BK5,Q9NZM5,P49959,Q7Z7L1,Q96EA4,Q12959,P15927,P61254,Q6NUQ1,Q14674,P51530,Q96JB5,P24941,P12270,O14757,P16104,Q99459,Q5JVF3,Q68E01,P41227,Q92547,P54132,Q9UNS1,Q96RU2 24 +Nadh regeneration 0.2492519449431408 0.0173352341651306 0.9861691770227698 1.0 1.0 9 P09104,P52789,P85037,P19367,P06733,P17858,Q01813,P08237 8 +Positive regulation of t cell mediated immunity 0.2328849028400717 0.0166965889759626 0.9866786683856592 1.0 1.0 6 P04439,O15400,Q12933,O43318,Q9NUQ9 5 +Regulation of myeloid leukocyte differentiation 0.2502071483003187 0.0158710229157978 0.9873372874540124 1.0 1.0 12 P17252,Q00534 2 +Heparan sulfate proteoglycan metabolic process 0.2381882821001293 0.0151795341492141 0.987888949165152 1.0 1.0 7 Q7LGA3 1 +Proteoglycan biosynthetic process 0.2381882821001293 0.0151795341492141 0.987888949165152 1.0 1.0 7 Q7LGA3 1 +Proteoglycan metabolic process 0.2381882821001293 0.0151795341492141 0.987888949165152 1.0 1.0 7 Q7LGA3 1 +Heparan sulfate proteoglycan biosynthetic process 0.2381882821001293 0.0151795341492141 0.987888949165152 1.0 1.0 7 Q7LGA3 1 +Calcium mediated signaling 0.2367167783219581 0.0148521834407099 0.988150107796106 1.0 1.0 22 P42345,P51572,P17252,O75844,P16615 5 +Glycolytic process through fructose 6 phosphate 0.2494011976047904 0.0145288009762771 0.9884081018301668 1.0 1.0 11 P51570,P09104,P52789,P85037,P19367,P06733,P17858,Q01813,Q9BRR6,P08237 10 +Double strand break repair 0.2303356590792188 0.0138801948508489 0.988925562428552 1.0 1.0 108 Q96FZ2,Q9BRT9,Q92993,Q9UBB9,P61160,P26583,P15927,Q9UBU8,P51530,P46063,P25490,Q8TDB6,O14757,P16104,P35244,Q14566,Q68E01,Q9NWY4,P33992,P09429,P54132 21 +Sarcoplasmic reticulum calcium ion transport 0.2477263295715505 0.0138137201326883 0.9889785964952736 1.0 1.0 10 P16615 1 +Regulation of hemopoiesis 0.2182200604602113 0.0100942607686741 0.9919460819546448 1.0 1.0 56 Q00534,P26583,O43290,P09429,Q99873,Q5JVF3,P17252 7 +Regulation of chromosome separation 0.2262371192004976 0.0099145059423995 0.9920894983777776 1.0 1.0 33 Q9Y6G9,Q13618,Q9UJX5,Q99741,Q9UJX4,P12270,Q13257,Q14674,Q14980,Q5JVF3,Q9H1A4,Q9UJX2,P53350,Q96EA4 14 +Vesicle docking 0.2419049306812306 0.0097391875329416 0.9922293754758162 1.0 1.0 15 O14795,O15400,O60763,O15498,Q12846 5 +Apoptotic process involved in development 0.1994041387822469 0.0073349984463251 0.994147570465144 1.0 1.0 6 O14757 1 +Epithelial tube formation 0.2283159741258556 0.0060966539945881 0.995135604039456 1.0 1.0 27 P17252,O60313,Q13043 3 +Regulation of chromosome segregation 0.2212426484109399 0.0053204514322858 0.9957549139734394 1.0 1.0 43 Q9Y6G9,Q13618,Q9UJX5,Q99741,Q9UJX4,P12270,Q13257,Q8IXJ6,Q00839,Q14674,Q99661,Q5JVF3,Q14980,Q9H1A4,Q9UJX2,P53350,Q96EA4 17 +Barbed end actin filament capping 0.2410958512580544 0.0046256552054459 0.996309274289532 1.0 1.0 12 P35241,P52907,P47755 3 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.2396318489266323 0.0041787706504575 0.9966658331184726 1.0 1.0 11 Q12959 1 +Actin cytoskeleton reorganization 0.2269428583792871 0.0038163718221601 0.99695498323644 1.0 1.0 28 P15311,Q13576,O94887,Q9UQB8 4 +Positive regulation of peptidyl tyrosine phosphorylation 0.2346291630712214 0.000290185821428 0.999768465216568 1.0 1.0 17 P14174,Q92974,P42345 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7838518107de9b812614be800cc1fc4a738d74f2 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosomal vesicle exocytosis", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Atrioventricular valve development", "Atrioventricular valve formation", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to laminar fluid shear stress", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule exocytosis", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic camera type eye formation", "Embryonic camera type eye morphogenesis", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic eye morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cell differentiation", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteric nervous system development", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Follicle stimulating hormone secretion", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of anatomical boundary", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G1 to g0 transition involved in cell differentiation", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve formation", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine catabolic process", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte apoptotic process", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesendoderm development", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle cell differentiation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell differentiation", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of epithelial to mesenchymal transition", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrogen peroxide metabolic process", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Negative t cell selection", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic cup morphogenesis involved in camera type eye development", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of gonadotropin secretion", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of mucus secretion", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic dense core vesicle exocytosis", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinolinate metabolic process", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of gonadotropin secretion", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of luteinizing hormone secretion", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Renal water transport", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to fluoride", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to laminar fluid shear stress", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell antigen processing and presentation", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymic t cell selection", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transforming growth factor beta2 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C17orf75", "C19orf70", "C1QBP", "C20orf27", "C21orf59", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COASY", "COG2", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROAP", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["AAR2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABHD10", "ABRAXAS2", "ACOT8", "ACOX1", "ACOX3", "ACSF3", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ADD3", "ADK", "ADPGK", "AFF4", "AFG3L2", "AGL", "AHSA1", "AIFM1", "AK6", "AKAP9", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDOA", "ALDOC", "ALG11", "ALG5", "ALG9", "ALKBH5", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANKFY1", "ANKLE2", "ANO6", "ANXA1", "APC", "APEX1", "API5", "APIP", "APLP2", "APRT", "ARCN1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARIH1", "ARIH2", "ARMT1", "ARPC1A", "ARPC4", "ASCC3", "ASNA1", "ATAD3A", "ATAD3B", "ATG16L1", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "AURKA", "B3GALT6", "BAG4", "BAG6", "BAIAP2", "BCAP31", "BCL10", "BCL2L13", "BCLAF1", "BLM", "BLVRA", "BRAT1", "BRD2", "BRD4", "BRMS1L", "BSG", "BTAF1", "BTF3", "C12orf57", "C20orf27", "C21orf59", "CADM1", "CALD1", "CAMK2D", "CAMK2G", "CAPN2", "CAPZA1", "CAPZA2", "CARNMT1", "CARS", "CARS2", "CASP8", "CBFB", "CBX3", "CC2D1A", "CCDC22", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC6", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CELF1", "CEP112", "CERS2", "CFAP20", "CHCHD3", "CHD1L", "CHD3", "CHEK1", "CHKA", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKB", "CKMT1A*", "CLASP2", "CLCN3", "CLIC1", "CLIP1", "CLPB", "CLPTM1", "CLUH", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COG7", "COL4A3BP", "COMT", "COPG1", "COPG2", "COPS7A", "COPZ1", "CORO1B", "CORO1C", "COX2", "COX6B1", "CPOX", "CPT2", "CRABP2", "CRTAP", "CS", "CSNK2B", "CSRP2", "CTNNA1", "CTNNBL1", "CTR9", "CTU2", "CUL3", "CUL5", "CYFIP2", "CYP51A1", "DAGLB", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTPP1", "DCUN1D1", "DCUN1D5", "DDRGK1", "DDX23", "DDX3X", "DDX47", "DHCR24", "DHFR", "DHRS7B", "DHX29", "DHX33", "DHX34", "DHX36", "DHX9", "DIABLO", "DICER1", "DLG1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC17", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DOHH", "DRG1", "DST", "DTNA", "DTX3L", "DTYMK", "DUSP3", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECD", "ECE1", "ECSIT", "ECT2", "EEA1", "EEF1D", "EEFSEC", "EIF1", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3E", "EIF5", "ELL", "EMC2", "EMC3", "ENO1", "ENO2", "EP300", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC3", "ERLIN1", "ERLIN2", "ESPL1", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC7", "EZR", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM49B", "FAM98A", "FAM98B", "FARP2", "FARSA", "FASN", "FASTKD5", "FBXO22", "FDFT1", "FERMT2", "FLAD1", "FLOT1", "FLOT2", "FNTA", "FOXK1", "FUBP1", "FXR2", "GALK1", "GALNT1", "GARS", "GATB", "GBA", "GCC2", "GCLM", "GDE1", "GET4", "GFM1", "GFPT1", "GGCX", "GINS3", "GINS4", "GLRX", "GLUD1", "GMFB", "GMPPB", "GNA11", "GNA13", "GNAI1", "GOLGA2", "GOLGA5", "GOLGB1", "GOPC", "GPSM1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTZ1", "GTF2H4", "GTPBP3", "GYG1", "H2AFX", "HACD3", "HARS2", "HDAC1", "HDAC6", "HEXIM1", "HIF1AN", "HK1", "HK2", "HLA-A", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPD", "HNRNPLL", "HNRNPU", "HPF1", "HPRT1", "HS2ST1", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPB1", "HYOU1", "ICE2", "ICMT", "IDE", "IDI1", "IFT27", "IKBIP", "ILK", "ILVBL", "IMPDH2", "INCENP", "INTS13", "INTS3", "IQGAP2", "ITSN2", "IWS1", "JMJD6", "KAT5", "KAT7", "KCTD10", "KCTD5", "KDELR1", "KDM3A", "KDSR", "KIAA0391", "KIAA1468", "KIF15", "KIF1B", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KLC2", "KTN1", "KYAT3", "LANCL2", "LARP1", "LCLAT1", "LCMT2", "LETM1", "LGALS3", "LIG1", "LIMD1", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LRPAP1", "LRRC59", "LSG1", "LSM4", "LTV1", "LUC7L2", "MAD2L1", "MAN1A1", "MANF", "MAP1A", "MAP2K2", "MAP2K3", "MAP3K7", "MAPK1", "MAPK3", "MAPK7", "MARK2", "MBD1", "MBOAT7", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MECP2", "MED1", "MED16", "MED21", "MED24", "MEPCE", "METAP1", "METAP2", "MFN1", "MFN2", "MGEA5", "MID1", "MIF", "MORF4L1", "MOV10", "MPG", "MPRIP", "MPV17L2", "MRE11", "MRPL10", "MRPL23", "MRPL24", "MRPL28", "MRPS16", "MRPS27", "MSH3", "MSI1", "MSMO1", "MSN", "MTA1", "MTAP", "MTCH1", "MTCH2", "MTFP1", "MTIF2", "MTMR2", "MTOR", "MTX1", "MTX2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYO1D", "MYO5A", "NAA10", "NAA15", "NAA40", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAPG", "NCAPD3", "NCAPG2", "NCBP1", "NCKAP1", "NCOR1", "NCSTN", "NDC1", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "NELFE", "NF1", "NF2", "NFAT5", "NIPBL", "NIPSNAP2", "NMD3", "NONO", "NOP53", "NPC1", "NPLOC4", "NSFL1C", "NSUN2", "NSUN4", "NSUN5", "NT5C3B", "NTMT1", "NUB1", "NUCB2", "NUDT12", "NUDT16", "NUF2", "NUMA1", "NUP93", "OCRL", "OGDH", "OPA1", "ORC3", "OSBPL9", "OTUD4", "OTUD7B", "OXSR1", "P3H1", "P4HA1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAIP1", "PAIP2", "PAK2", "PARP1", "PCBP2", "PCID2", "PCNP", "PCYOX1", "PDCD4", "PDCD5", "PDCL3", "PDE12", "PDE4DIP", "PDIA3", "PDLIM7", "PEX14", "PEX19", "PEX5", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PGAM5", "PGM2", "PGRMC1", "PGRMC2", "PHACTR4", "PHB2", "PHF6", "PI4KA", "PI4KB", "PIAS4", "PIGK", "PIGS", "PIK3R4", "PINX1", "PIP4K2A", "PIR", "PISD", "PITPNA", "PKN1", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLK1", "PLOD3", "PLS1", "PMPCA", "PMVK", "PNP", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE4", "POLRMT", "PON2", "POR", "PPHLN1", "PPIF", "PPIL4", "PPM1F", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP5C", "PPT1", "PRC1", "PRCP", "PRDX5", "PREPL", "PRKAA2", "PRKAG1", "PRKCA", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPS2", "PRPSAP1", "PRPSAP2", "PRTFDC1", "PSAP", "PSMB2", "PSMC1", "PSMC5", "PSMD10", "PSMD11", "PSMD13", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTK7", "PTPA", "PTPN11", "PUF60", "PUS1", "PUS7", "PWP1", "PYCR2", "QARS", "QKI", "QRICH1", "QTRT1", "RAB1A", "RAB1B", "RAB27A", "RAB3GAP2", "RAB9A", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD23A", "RAD50", "RAD54L2", "RAI14", "RARS", "RARS2", "RAVER1", "RBM4", "RBPJ", "RCC2", "RCN1", "RCOR1", "RDH13", "RDX", "RECQL", "REV1", "RFC3", "RFTN1", "RHOA", "RIC8A", "RINT1", "RIOX2", "RIPK1", "RNF20", "RNF219", "RNF40", "ROCK1", "ROCK2", "RP2", "RPA2", "RPA3", "RPL10", "RPL11", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL3", "RPL31", "RPL37A", "RPL5", "RPL8", "RPN1", "RPN2", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS23", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "RREB1", "RRN3", "SAMHD1", "SARS", "SART1", "SART3", "SASS6", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCO2", "SCPEP1", "SCYL2", "SEC11A", "SEC13", "SEH1L", "SENP3", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SETD3", "SF1", "SF3B5", "SFPQ", "SFXN4", "SGPL1", "SHMT2", "SHTN1", "SIRT2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC27A2", "SLC35B2", "SLC9A3R1", "SLFN11", "SLIT2", "SLTM", "SMAD4", "SMARCA4", "SMARCAD1", "SMARCE1", "SMC1A", "SMC3", "SMC6", "SMG5", "SNU13", "SNW1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SPDL1", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRM", "SRP19", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRB", "SRRT", "SSB", "SSBP1", "SSR1", "STAMBP", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STUB1", "STX18", "STX4", "STX7", "SUPV3L1", "SYNCRIP", "SYNE2", "SYNGR2", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D9B", "TBCD", "TBRG4", "TCP1", "TDRKH", "TFAM", "TFAP4", "TFIP11", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8B", "TK1", "TKFC", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED7", "TMEM126A", "TMEM167A", "TMEM199", "TMEM201", "TMEM97", "TMOD3", "TMTC3", "TOMM22", "TOMM5", "TOMM70", "TOPBP1", "TOR1AIP1", "TPM3", "TPM4", "TPR", "TRA2A", "TRAF2", "TRAPPC11", "TRAPPC8", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIP13", "TRIP4", "TRMT10C", "TRMT61A", "TRRAP", "TRUB2", "TSC2", "TSG101", "TSN", "TSR3", "TSTA3", "TTC19", "TTC7B", "TTLL12", "TUBB4A", "TUBG1", "TUBGCP2", "TWNK", "TXLNG", "TXNDC9", "TYMS", "UBA5", "UBAP2L", "UBE2S", "UBR4", "UBTF", "UCHL5", "UFC1", "UFL1", "UFM1", "UFSP2", "UMPS", "UNC13B", "UNG", "UQCC1", "UQCR10", "UQCRC2", "UQCRQ", "USO1", "USP28", "UTP11", "UTRN", "VAC14", "VAPA", "VBP1", "VCL", "VDAC1", "VDAC2", "VIM", "VPS18", "VPS33A", "VPS33B", "VPS35", "VPS52", "VRK1", "WARS", "WDR6", "WDR7", "WDR70", "WIPI2", "WTAP", "XAB2", "XIAP", "XPO4", "XPO5", "XRCC1", "XRN2", "YBX1", "YIF1A", "YKT6", "YME1L1", "YTHDF3", "YY1", "ZC3H13", "ZC3H15", "ZCCHC3", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_gocc/advanced/idx2term.json b/msigdb_gocc/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..dd4ceacb340e60a8bf49a243468336fb47182c04 --- /dev/null +++ b/msigdb_gocc/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Mitochondrial envelope", "2": "Mitochondrial protein containing complex", "3": "Envelope", "4": "Inner mitochondrial membrane protein complex", "5": "Mitochondrion", "6": "Organelle subcompartment", "7": "Protein kinase complex", "8": "Intrinsic component of mitochondrial membrane", "9": "Nuclear outer membrane endoplasmic reticulum membrane network"} \ No newline at end of file diff --git a/msigdb_gocc/advanced/plot_0.png b/msigdb_gocc/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1ef79a694705599a33dc31d5c98d6e0779c58471 --- /dev/null +++ b/msigdb_gocc/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:26fe8dabf7cea7e1582d6484f7d0dd7428b33ac4c9a4f06f39d24da7dc6b5f89 +size 229611 diff --git a/msigdb_gocc/advanced/plot_1.png b/msigdb_gocc/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f2735d0d1379a40d3b40975db159cf1225a91c41 --- /dev/null +++ b/msigdb_gocc/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d48f9bbf05ea3da5bfd2885b350fbe310df98b63f68cc54a1301c76abe2de53e +size 232443 diff --git a/msigdb_gocc/advanced/plot_2.png b/msigdb_gocc/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..893c21d8c1a6fd70cddf721294d316ec7804943d --- /dev/null +++ b/msigdb_gocc/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c998b77172982a0bd168d17fd4f0b6efea841bf0ed0007e8e897003085a7bd0e +size 227566 diff --git a/msigdb_gocc/advanced/plot_3.png b/msigdb_gocc/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..fef246097869e101aa2b3669cb92be9d7f48ba86 --- /dev/null +++ b/msigdb_gocc/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a25e80bfdd6dcc681afca4fd1976cb9d8f0e0c87fca248341afb9b3e8891fea7 +size 233977 diff --git a/msigdb_gocc/advanced/plot_4.png b/msigdb_gocc/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..455a258b0b0f054869453ea40db3fa67e8cd6170 --- /dev/null +++ b/msigdb_gocc/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e9b61d17a4126c01365204b9f935e279a1913296869df69363e118ad54cc429 +size 217242 diff --git a/msigdb_gocc/advanced/plot_5.png b/msigdb_gocc/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..20cac2bc85f9edc88013eddb64026ad6870f9cdf --- /dev/null +++ b/msigdb_gocc/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74c04ffe1bc5b6cb707488e2cf68ea0e56af14d7024f2aaac0c210f380b7ca40 +size 237987 diff --git a/msigdb_gocc/advanced/plot_6.png b/msigdb_gocc/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..5a98af7dac2ff5ab5951903ca9e1e2a3a020ce86 --- /dev/null +++ b/msigdb_gocc/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8942c41a529f607492044155b7d524b3382c11ac5d9f567be3ad7b245dd1b900 +size 236012 diff --git a/msigdb_gocc/advanced/plot_7.png b/msigdb_gocc/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..2b7d4556589bf8f13a8969fbfcda2f06a890fee6 --- /dev/null +++ b/msigdb_gocc/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5256b388236a1854442d785bc92bdf4ec048d360d386cf209638467b0a1245ec +size 202855 diff --git a/msigdb_gocc/advanced/plot_8.png b/msigdb_gocc/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..fcc78d9b8e88dcb24f276263a1798da17f0d07bf --- /dev/null +++ b/msigdb_gocc/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56ced400d732719f09404247644e222f6d1d8e5b7480d5cc5b8fcfe6e8e59699 +size 212027 diff --git a/msigdb_gocc/advanced/plot_9.png b/msigdb_gocc/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9cadae7a2db03a51aafe117296f5591c27db5e1b --- /dev/null +++ b/msigdb_gocc/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ecccd833c005cbbd7fa3fb51ce788fd9908f5fdc6724a391862d2a96fb67950b +size 240814 diff --git a/msigdb_gocc/basic/idx2term.json b/msigdb_gocc/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1888ca5c7bcc651790712647ac8ebeaf3634b043 --- /dev/null +++ b/msigdb_gocc/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Mitochondrial envelope", "2": "Mitochondrial protein containing complex", "3": "Envelope", "4": "Inner mitochondrial membrane protein complex", "5": "Mitochondrion", "6": "Organelle subcompartment", "7": "Protein kinase complex", "8": "Intrinsic component of mitochondrial membrane", "9": "Nuclear outer membrane endoplasmic reticulum membrane network", "10": "Endoplasmic reticulum golgi intermediate compartment", "11": "Golgi apparatus", "12": "Transporter complex", "13": "Non motile cilium", "14": "Cis golgi network", "15": "Microtubule associated complex", "16": "Endoplasmic reticulum", "17": "Nucleoid", "18": "Polymeric cytoskeletal fiber", "19": "Endoplasmic reticulum golgi intermediate compartment membrane", "20": "Cilium", "21": "Ciliary basal body", "22": "Proton transporting two sector atpase complex", "23": "Membrane protein complex", "24": "Secretory granule membrane", "25": "Caveola", "26": "Respirasome", "27": "Plasma membrane raft", "28": "Post mrna release spliceosomal complex", "29": "Intrinsic component of organelle membrane", "30": "Microtubule cytoskeleton", "31": "Rough endoplasmic reticulum", "32": "Golgi membrane", "33": "Outer membrane", "34": "Collagen containing extracellular matrix", "35": "Microtubule organizing center", "36": "Cortical cytoskeleton", "37": "Organelle envelope lumen", "38": "Supramolecular polymer", "39": "Actin cytoskeleton", "40": "Actin filament", "41": "Vacuolar membrane", "42": "Golgi stack", "43": "Filopodium", "44": "Centrosome", "45": "Membrane microdomain", "46": "Proton transporting atp synthase complex", "47": "Cytoplasmic region", "48": "Neuromuscular junction", "49": "Kinesin complex"} \ No newline at end of file diff --git a/msigdb_gocc/basic/plot_0.png b/msigdb_gocc/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e59fe8a5d4c78626854ab304300f9e2dd74f97aa --- /dev/null +++ b/msigdb_gocc/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:19f42a99b3a5de0cc219693ad7c23408b83cb338419e0e2cc7c58e0058c8d8fc +size 146837 diff --git a/msigdb_gocc/basic/plot_1.png b/msigdb_gocc/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fbc5aeb211dae2d7b51530057bc53cd483c3d264 --- /dev/null +++ b/msigdb_gocc/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d5aa287ef21b2058da1793a0b4d716e550d2c311d1f11a19ba540a05fb9a7f5 +size 144453 diff --git a/msigdb_gocc/basic/plot_10.png b/msigdb_gocc/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..68e863e9c6c2f1fb38c42b4cdd6cf9a172375489 --- /dev/null +++ b/msigdb_gocc/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9030afa3e6cfe646f9180dd80acbf4d8c1de3184c96458fe4af1ae08a0b891a +size 142168 diff --git a/msigdb_gocc/basic/plot_11.png b/msigdb_gocc/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..7186a9a61bf2d18614365d141e32f8d30b6304f9 --- /dev/null +++ b/msigdb_gocc/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69a5e44e14ee4082c8ee52a8b88db0720cdbd5e87af8f5d2401e13a7346b625f +size 138510 diff --git a/msigdb_gocc/basic/plot_12.png b/msigdb_gocc/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..ca37bd5b6f211e773917f9bda1b988b313e3a786 --- /dev/null +++ b/msigdb_gocc/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6e882f96d6d602d8d48637a93bba7211838dfa92b7e63a10cff4183b5f29a05 +size 140041 diff --git a/msigdb_gocc/basic/plot_13.png b/msigdb_gocc/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..8198868beaa3b0c358cf28592271d68f890b5743 --- /dev/null +++ b/msigdb_gocc/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09d008c0b7d2eca46922261981959d0e67ac0bd0d214824b7a4bbb5b934607c5 +size 131147 diff --git a/msigdb_gocc/basic/plot_14.png b/msigdb_gocc/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..3f60051d79045d1aeaea650ec2f76c927bcdd2f6 --- /dev/null +++ b/msigdb_gocc/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33c98959335b57bc0036c3dd91f5672d2cbd684720e76f5086ccc1310f9c639a +size 133749 diff --git a/msigdb_gocc/basic/plot_15.png b/msigdb_gocc/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..b3e7f3eb25def3f53ec119832563e958be6d7e36 --- /dev/null +++ b/msigdb_gocc/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:500e48a820da7c19555d5d214529cd293b3e259dc2dbf9cadf7a250ab50a92db +size 144323 diff --git a/msigdb_gocc/basic/plot_16.png b/msigdb_gocc/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..332cb1c0bb57117d1f83ccbb34e86997cd8a558c --- /dev/null +++ b/msigdb_gocc/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b62e2f3f4c027ec05f6c9a122bfb6dfd5778c5118030700bd753957a425bc824 +size 139882 diff --git a/msigdb_gocc/basic/plot_17.png b/msigdb_gocc/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..daf7a41c6634c3284813b70458acfad5e19ba8b0 --- /dev/null +++ b/msigdb_gocc/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ead667bb55a233f7e7c49bdc5d71ade73fb2e0b470ead084fd8670ba97563cc3 +size 127411 diff --git a/msigdb_gocc/basic/plot_18.png b/msigdb_gocc/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..1a35ba61ce409897f12df1e15b9a69846b523948 --- /dev/null +++ b/msigdb_gocc/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b4745ca3255f5a615d6ca14f8a274f139c101b160a7bba9fb71ea331d596633f +size 141605 diff --git a/msigdb_gocc/basic/plot_19.png b/msigdb_gocc/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..30b0e6f7fddf96b95b8d88f06984617d9f06271a --- /dev/null +++ b/msigdb_gocc/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:215afd0c8ff12264ed286012182f876f8b8f27337c7dd100db0621629873a4e6 +size 139551 diff --git a/msigdb_gocc/basic/plot_2.png b/msigdb_gocc/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..97401a0d278e3a8191300a905bb8e10449012a51 --- /dev/null +++ b/msigdb_gocc/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2669c9bf790aee2cc58244b74071424bb504858aabe366632600c167a61c81f1 +size 151787 diff --git a/msigdb_gocc/basic/plot_20.png b/msigdb_gocc/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..c79dcc860f4a41efa870dd548a69d4b244065aca --- /dev/null +++ b/msigdb_gocc/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:98df2093fabbac6defee89ea31a5289e1e875101587f0d6a95733a1ac6bd7820 +size 132677 diff --git a/msigdb_gocc/basic/plot_21.png b/msigdb_gocc/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..01792e9d6df6eca4e74d00e9c93f0f01e6656e12 --- /dev/null +++ b/msigdb_gocc/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06de7b1cb2168b86b853d7e735f526792b8ee27ffd4a78da2f6fd31a566b798d +size 133398 diff --git a/msigdb_gocc/basic/plot_22.png b/msigdb_gocc/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..39e6b6fd7091c3ec7f37e21538f0de2aea37b69f --- /dev/null +++ b/msigdb_gocc/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfd6d73fc5fafe9fdbfa4a26b86a1927eb6313154a16b74f80714c41cb4a01bd +size 140534 diff --git a/msigdb_gocc/basic/plot_23.png b/msigdb_gocc/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..3988240b19a7552a799b363d3b86b1f5685418e9 --- /dev/null +++ b/msigdb_gocc/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b77ef53a3772408ef7adeacd3eca17bb4d4c14c119dcc32159b0b1c607354cb4 +size 143557 diff --git a/msigdb_gocc/basic/plot_24.png b/msigdb_gocc/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..bdb383c17d0114ad98047d54214aa598044e1695 --- /dev/null +++ b/msigdb_gocc/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f56684f3ca11d597d245b5edf824b52ab4b7c1b8f66889eb4ca22439a8d227c +size 138784 diff --git a/msigdb_gocc/basic/plot_25.png b/msigdb_gocc/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..4a51336e0ae4bd6f522a4308224350ef4afff82d --- /dev/null +++ b/msigdb_gocc/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35a4c5fc9ff1e46a21a2d70a16d4b545d768c7c4c2e9a4cb0268b12b425890f9 +size 128939 diff --git a/msigdb_gocc/basic/plot_26.png b/msigdb_gocc/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..9a5876b76b064bded9cd6687cc03b192b4bcd66c --- /dev/null +++ b/msigdb_gocc/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a7a31aea760f9f788553b3335bbfeb0be151f6643cda05681fbdee88f9385131 +size 138311 diff --git a/msigdb_gocc/basic/plot_27.png b/msigdb_gocc/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..ccc720713021a4ad4e2c2c5a97a0eaeba307cf74 --- /dev/null +++ b/msigdb_gocc/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10a011be02fede13146b411009ad9ebe1a5d4b3dbe5c6420a71f5ea0a38c420a +size 141171 diff --git a/msigdb_gocc/basic/plot_28.png b/msigdb_gocc/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..88a4c103c181c3f4def2cd4cf95151383d8fe919 --- /dev/null +++ b/msigdb_gocc/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e48615174de0526e8f3552cd5a724c2d227eca7b1d03e00704d38bf34f2a99fc +size 132928 diff --git a/msigdb_gocc/basic/plot_29.png b/msigdb_gocc/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..897ce445b212b0d7e013dc69ad0675b21c915f04 --- /dev/null +++ b/msigdb_gocc/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97fbdea6ff31c66e4d3932b338ef8136cf89e8fc70234fae312bf65d1775078b +size 147660 diff --git a/msigdb_gocc/basic/plot_3.png b/msigdb_gocc/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..53caf6bcc72acd1b15f7eb8c38efd1f01834a9db --- /dev/null +++ b/msigdb_gocc/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dbfd2fc5471fda145cf7d093931bf0e1de64f83bfc46ec38e68995b7a53d9023 +size 136162 diff --git a/msigdb_gocc/basic/plot_30.png b/msigdb_gocc/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..af238b0d5ddc24c2f987384573af55beacbf7da4 --- /dev/null +++ b/msigdb_gocc/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48e31bc68b72a734ba225008511dbfa9cc06bc9b9f617ee39973aac67ca759e0 +size 136567 diff --git a/msigdb_gocc/basic/plot_31.png b/msigdb_gocc/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..e2c7d41f27305108d22b6981f92d90e343ec91c3 --- /dev/null +++ b/msigdb_gocc/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:922442efd76059b740ba2eb885ace90240df3f9c8792417e1eb0d830d0f71ddd +size 141271 diff --git a/msigdb_gocc/basic/plot_32.png b/msigdb_gocc/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..2df61ce26c7b076d8822557db531f27c5e7f57a6 --- /dev/null +++ b/msigdb_gocc/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cec8cef1acb9fbf5aa10675658334498d1e8951d7f21a8b8dff384e468dc5e51 +size 139448 diff --git a/msigdb_gocc/basic/plot_33.png b/msigdb_gocc/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..3cad64190cd8336f9f44d3711dae7ce0e9105fa8 --- /dev/null +++ b/msigdb_gocc/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4cd215074e7868a0aa4c8774ee23457ee1985dca89748e151fc604fd2f9b8c42 +size 140024 diff --git a/msigdb_gocc/basic/plot_34.png b/msigdb_gocc/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..2053f5f0f03640f3fc6fde28618aebd32ea1f03a --- /dev/null +++ b/msigdb_gocc/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58049075781614d19ec99d6368df30f3d5822f66c88b30962b7486866584daa4 +size 142984 diff --git a/msigdb_gocc/basic/plot_35.png b/msigdb_gocc/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..635e9e1721556d4e8d4d347d7ec10f6604e62885 --- /dev/null +++ b/msigdb_gocc/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:966bfb64a475dab3e9f243649db8e06aa913948954768e10cb0ae75ed93976ea +size 144034 diff --git a/msigdb_gocc/basic/plot_36.png b/msigdb_gocc/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..9570bd954d6bfe0500fc5c7092f1e2d8c28cc08a --- /dev/null +++ b/msigdb_gocc/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2c708667bceb1125f8f525970d7f1e605f9dd606014de852174786225ae1b23 +size 143428 diff --git a/msigdb_gocc/basic/plot_37.png b/msigdb_gocc/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..52ddefe77fbe14cf0fa0f93f67dcae27f27c208c --- /dev/null +++ b/msigdb_gocc/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca5d8dd99966ecc410879588523c17687fd4379e4ab7affb69733863cee7e0ad +size 144255 diff --git a/msigdb_gocc/basic/plot_38.png b/msigdb_gocc/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..8b829e98823bb431f738b943640a5dc012fc1715 --- /dev/null +++ b/msigdb_gocc/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e838f667aec21d66c0c9046183613a15bec618cd77221ceb03a698374b1d8c75 +size 141383 diff --git a/msigdb_gocc/basic/plot_39.png b/msigdb_gocc/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..a6ca5d965f96726e279920059ccbe2849d36b64a --- /dev/null +++ b/msigdb_gocc/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e26022e9043ca5eec9c8222f90f3e89ea282d7658921e6049549230ff91f1d8 +size 142945 diff --git a/msigdb_gocc/basic/plot_4.png b/msigdb_gocc/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..68b5b9aafaea090c061ffeb2907b52d04864d003 --- /dev/null +++ b/msigdb_gocc/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9ef11d37eb3fff15f1d4c849e7f33d268fc9eada907c74a978346b912da0d6d +size 148875 diff --git a/msigdb_gocc/basic/plot_40.png b/msigdb_gocc/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..8251d61a3614858a7dfac81918f1145b400467a9 --- /dev/null +++ b/msigdb_gocc/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:85321cb63fe116c436931712602df52f550a5663aa18105f6148489b06b927c2 +size 134780 diff --git a/msigdb_gocc/basic/plot_41.png b/msigdb_gocc/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..60e3e7f33b25f6ccf50e82b68cfbb08cc876fee5 --- /dev/null +++ b/msigdb_gocc/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb660048c24a5ba3f3f545c631146ddf7c072e6cd203d25b5ac9b2b5119cb89d +size 143170 diff --git a/msigdb_gocc/basic/plot_42.png b/msigdb_gocc/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..67624d3bb3b92b040a38c08bf5796e4d083f8858 --- /dev/null +++ b/msigdb_gocc/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:673bfc638e87216884c1ecc8c2034d0a5a853298637cd29dbadd524d945bf860 +size 136883 diff --git a/msigdb_gocc/basic/plot_43.png b/msigdb_gocc/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..6050a617e588e1e042ba19910dbd8a70faf31609 --- /dev/null +++ b/msigdb_gocc/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef8bfb24239a4b86998f00228ee00c8882fed6e088ead1962d31ba301ad5fcb4 +size 138029 diff --git a/msigdb_gocc/basic/plot_44.png b/msigdb_gocc/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..ba44bb00ef2d20926b575ffc9222f64e135c272a --- /dev/null +++ b/msigdb_gocc/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:613cf9ec9b0af5cca6ed5888ddd9dd12ebd1cab771341af103c6a75917975c76 +size 140205 diff --git a/msigdb_gocc/basic/plot_45.png b/msigdb_gocc/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..78187135792efb350aa4af2475ccec74616a9bd2 --- /dev/null +++ b/msigdb_gocc/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8182d8d42f9b81b4fe51a665053d85a1b385b02aa957b421b219828b7c8106c4 +size 142575 diff --git a/msigdb_gocc/basic/plot_46.png b/msigdb_gocc/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..cb8709b764c59312836c2b4eee4924f6a818c12c --- /dev/null +++ b/msigdb_gocc/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b4e3f508af08ef1b075e25ce1b80719a6c004caca520a9dfa33c63fdf26749f +size 140084 diff --git a/msigdb_gocc/basic/plot_47.png b/msigdb_gocc/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..1cc1b4a17277eddbef23560e5fb91f1bd308ace6 --- /dev/null +++ b/msigdb_gocc/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a931b424e6f49ec5dd5fe4a661bff8250d3144b66bd36b57d052124a7a95b9c +size 145229 diff --git a/msigdb_gocc/basic/plot_48.png b/msigdb_gocc/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..ced2d1912ff0297f128016f690ac00eca01acac7 --- /dev/null +++ b/msigdb_gocc/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:387cced1a4d984f9a84ecf1035737872a02fd1f42b024a25bd3c511a78e7bb49 +size 140919 diff --git a/msigdb_gocc/basic/plot_49.png b/msigdb_gocc/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..74a5d49d172a237d05aafa88bd2061b21fe7609d --- /dev/null +++ b/msigdb_gocc/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b56609fa474363787c2ad88f059f017c32d74eb91991ba54cc7c1cc9964ea25b +size 133525 diff --git a/msigdb_gocc/basic/plot_5.png b/msigdb_gocc/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..fb6c7c5db944cb582349d8b105449237cb1603ba --- /dev/null +++ b/msigdb_gocc/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3247a2a9e9c9037f70855e173b1acbc09a32086d1c0cb2fb08620f5e7372b6c +size 136921 diff --git a/msigdb_gocc/basic/plot_6.png b/msigdb_gocc/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..56fd3acf9b354418ffc48ad2643169d2ac17df6c --- /dev/null +++ b/msigdb_gocc/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72589e30506dd74ca5c013ca969dd1fa0abd6ebf1a040ade522519e865942874 +size 145462 diff --git a/msigdb_gocc/basic/plot_7.png b/msigdb_gocc/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..10476d3df8b59ea527ff5124015b073828365b62 --- /dev/null +++ b/msigdb_gocc/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fdebea6516ecf61dcaacbdaf809c0edc22ea26b2db56172a9be4ba01d5c928e +size 140054 diff --git a/msigdb_gocc/basic/plot_8.png b/msigdb_gocc/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..4354acfdf6fd08edcca82df7ea2083c46cfbec4c --- /dev/null +++ b/msigdb_gocc/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1699a6e4c3b9fb7360954a970324647b58fee853f752b7a17b3df1d69a8b5d55 +size 143214 diff --git a/msigdb_gocc/basic/plot_9.png b/msigdb_gocc/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..bd85a11ff8b7f51bb9610c4422e6e96897e68d91 --- /dev/null +++ b/msigdb_gocc/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0519e727474ad2b9d847074d0de6f70dabd3d13b640bfac0259e02c216ae9ef +size 147213 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0cf4d7aadb843cf038a5755a86508f5039e100b3 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8d7241de62765839a9b04f37c1011407697dfac66db5af0fd9398f2c26f8982 +size 152672 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2600ed4ff5d3bbbb2647fcfcf74b6cea3b1bd0b5 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,24 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Organelle inner membrane 64 228 5.643813783060256 1.6632396812939878e-08 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 0.0001700716540809 4.2677713647645446e-06 3.885521035967264e-11 1.2657152053880678e-13 +Mitochondrial envelope 61 293 5.591882238243647 2.246211527856214e-08 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 3.942889521936557e-06 1.835714307844644e-06 4.210387441335019e-12 2.8235653861032548e-11 +Mitochondrial protein containing complex 46 152 3.389590767608561 0.000699970316073 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 1.8531084161777407e-05 0.0001492328733144 9.368486379679026e-07 7.652198285761905e-07 +Envelope 76 465 3.2726192509130194 0.0010655591201296 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 0.0003917626840658 4.112586788954942e-05 1.1092276245102777e-10 1.2419683600550474e-09 +Inner mitochondrial membrane protein complex 20 75 3.1162259329134363 0.0018318186663073 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 0.0003343057897301 0.0015853190109641 0.000353075219544 6.930857047648682e-05 +Intrinsic component of mitochondrial inner membrane 4 26 2.8388819264123666 0.0045271905417922 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 0.0221396463905691 0.0817843887075946 0.006984722202598 0.0101516407294213 +Mitochondrion 85 609 2.6604744287957987 0.0078030652161633 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 2.702976592591373e-06 2.5515215940534892e-08 2.949691438837002e-10 6.414662673332005e-08 +Organelle subcompartment 89 350 2.6119745057725 0.0090020966873909 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 0.0118672732348011 0.1323699552620265 0.0021043534539862 2.001311336179744e-05 +Protein kinase complex 7 32 2.604701894046511 0.009195422730732 9.305825242718448 26.640776699029125 0.0834251211245744 0.6520727496615577 5.442877687662837 4.410610262977704 0.8513500824364756 0.3106562213180078 0.0632391282058976 0.2075521457010754 0.1693080490378837 0.068025221638467 +Intrinsic component of mitochondrial membrane 5 39 2.5814107478296284 0.0098397430899457 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 0.0512049491784678 0.1731294929006003 0.0121231126733016 0.0380095176885234 +Nuclear outer membrane endoplasmic reticulum membrane network 76 286 2.537005654502828 0.0111805148253356 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 0.006780522841113 0.0539261013112109 0.000652868311743 5.370364504979661e-05 +Tim23 mitochondrial import inner membrane translocase complex 1 6 2.5119517840656425 0.0120065491805483 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0011140257717061 0.0046590638338273 0.027832231049335 0.0974859568290139 +Endoplasmic reticulum golgi intermediate compartment 13 46 2.49290386837102 0.0126703144951672 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0748026769142899 0.0665208936005656 0.0096006639064149 0.0002671554170647 +Dynactin complex 1 5 2.293967122632349 0.0217923872974019 1.922330097087379 4.978155339805825 0.7536051706711276 0.4281847634474278 1.1982132360298303 0.5138929048129751 0.8369340042224647 0.3070790527939186 0.040745762787022 0.003087611696091 0.0188064524051028 0.0680064706612652 +Pore complex 2 8 2.2477714859600395 0.0245907649681829 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0027065615852008 0.0111011801010317 0.0074273483269255 0.0470360579614364 +Dynein complex 3 12 2.2291548858597188 0.0258036010752995 3.779126213592233 11.347087378640778 0.0137775724407904 0.5955821430721882 2.3039120831713062 1.5867828667311044 0.8314129562783991 0.2933565758209187 0.1255618233886208 0.0307863463383066 0.0322769586697076 0.012132108209414 +Golgi apparatus 58 305 2.219759335944484 0.0264351086226852 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.0152721776975736 0.1624442036349252 0.3264835814098664 0.061725812081453 +Transporter complex 14 54 2.211004186937431 0.0270355471207341 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 0.1485717214577993 0.1666719780928332 0.0274278527807438 0.0131533427482152 +Non motile cilium 8 18 2.178146079912055 0.0293951628965394 4.058252427184466 14.99514563106796 -0.0255514592299957 0.7052763642129709 2.4118447305416826 2.951053083084061 0.6232735338296804 0.2681289777004501 0.290457955358921 0.5083206499791918 0.2664860397703889 0.0681816530513533 +Cis golgi network 5 11 2.095713214579221 0.0361076389019512 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.1651718851687308 0.3116816529125438 0.0142235096743441 0.010788368915323 +Microtubule associated complex 20 50 1.9987716567647569 0.0456330657994721 13.50485436893204 47.66990291262136 0.0924712472826301 0.6540803251543599 6.046540833133665 6.245601713788117 0.8846152481627416 0.3231371254728546 0.0997216591997759 0.0983849798809316 0.0625424494257227 0.1126148026781627 +Endoplasmic reticulum 118 452 1.9655390296565511 0.0493518829641252 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 0.0075492733406891 0.1096721781789321 0.0003733530980642 7.584676778318334e-06 +Cytoplasmic dynein complex 3 10 1.9635943268828884 0.0495771558312148 3.25 9.347087378640778 -0.1273459533679964 0.5459837817037768 2.0260739690730296 1.5867828667311044 0.902838569499687 0.300732072386452 0.0841142186818086 0.1662183776826317 0.0762921742488627 0.0120515986398723 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e4acebe85b4793f05f3eb1fd750092b438d9c107 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 904, + "title": "Average number of proteins per term", + "value": 29.359513274336283 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ea923e03db04da9e86150d1bfea7af6c85a31e2 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..96ebde86a22da79d28ca415495bcbf00468037e2 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,337 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle inner membrane 0.4976599278352501 5.643813783060256 1.6632396812939878e-08 1.5035573809468478e-05 1.0152876106362086e-05 228 O60830,Q9UDX5,Q92665,O43678,Q99595,Q70HW3,Q9Y2C4,Q9H2D1,O43615,Q9Y5J9,Q03252,Q9H2W6,Q9P015,O43676,Q567V2,O75964,Q96EY7,Q9P0J0,Q5T9A4,P51970,Q9NVH1,Q9NVA1,O60313,Q16540,Q9H1E5,Q709F0,Q9BQ95,Q96TA2,Q9HC21,Q10713,O75306,Q6DKK2,P36551,P82933,P06576,Q9Y6C9,Q9UBX3,Q9Y6N5,P22695,Q9UDW1,P56134,Q9H061,Q9BSK2,Q5SNT2,Q86Y39,Q6P4A7,P53701,Q9UJZ1,P18859,Q9Y5L4,P53007,P04818,O75380,P20700,P23786,Q9NX63,P14854,P12235,Q5JTV8,Q7Z7H8,Q92552,Q13505,Q9NVI7,Q9Y3D3 64 +Mitochondrial envelope 0.4514355800614006 5.591882238243647 2.246211527856214e-08 2.0305546280383572e-05 1.0152876106362086e-05 293 O60830,Q9UDX5,Q92665,Q99595,O43615,Q70HW3,Q9Y2C4,Q9H2D1,Q9Y5J9,Q9H2W6,O43676,Q567V2,O75964,Q96EY7,P21796,Q9NS69,P45880,Q9P0J0,Q8N4H5,Q5T9A4,P51970,Q9NVH1,Q9NVA1,P09601,O60313,Q16540,Q96TA2,Q709F0,Q9BQ95,Q10713,Q96A26,O75306,Q9NR28,Q6DKK2,P36551,P82933,Q9Y6C9,Q9UBX3,Q9H078,Q9Y6N5,P22695,Q9UDW1,O00429,Q9H061,Q9BSK2,P17252,Q6P4A7,Q4VC31,P53701,P18859,Q9Y5L4,P53007,P04818,O00264,Q9NX63,P14854,P12235,Q7Z7H8,Q13505,O43169,Q9Y3D3 61 +Mitochondrial protein containing complex 0.4256575457640778 3.389590767608561 0.000699970316073 0.4690007819525299 0.0263655485720849 152 O60830,O43678,Q99595,Q9Y5J9,Q9H2W6,Q9P015,O43676,Q567V2,O75964,P21796,Q9NS69,P25705,Q8IYB8,O75431,Q99623,P24539,Q9P0J0,Q8N4H5,P14406,P51970,P50213,Q9NVH1,Q16540,Q96CB9,Q9HAV7,O75306,O15091,O00411,P82933,P06576,Q9UDW1,P22695,P56134,Q96A35,Q86Y39,P18859,Q9Y5L4,O75380,O14925,Q9NX63,P14854,P12235,Q7Z7H8,Q92552,Q13505,Q9Y3D3 46 +Envelope 0.3382981128277134 3.2726192509130194 0.0010655591201296 0.6185513423780752 0.0282229088648605 465 O60830,Q9UDX5,P67809,Q92665,Q99595,O43615,Q70HW3,Q9Y2C4,Q9H2D1,Q03252,Q9Y5J9,Q9H2W6,Q8WUX9,O43676,Q567V2,O75964,Q03001,P21796,Q9NS69,P55735,Q96EY7,Q15125,P45880,Q9P0J0,Q8N4H5,Q5T9A4,P51970,Q9NVH1,Q9NVA1,P09601,O60313,Q16540,Q5BJF2,Q9H1E5,Q709F0,Q96TA2,Q9BQ95,Q10713,Q96A26,O15173,Q9NR28,O75306,Q6DKK2,P36551,Q96KC8,P82933,Q9Y6C9,Q9UBX3,Q9H078,Q9Y6N5,P22695,Q9UDW1,O00429,Q5JVF3,Q9H061,Q9BSK2,Q5SNT2,P17252,Q6P4A7,Q4VC31,P53701,P18859,Q9Y5L4,P53007,P04818,P80303,O00264,Q9NX63,P14854,P12235,Q7Z7H8,Q96EE3,Q13505,O43169,Q9Y3D3,Q9BTX1 76 +Mitochondrial intermembrane space protein transporter complex 0.9590922663481624 3.265502316427795 0.0010927011175554 0.6278066828034075 0.0282229088648605 2 Q9Y5L4 1 +Inner mitochondrial membrane protein complex 0.4815722932940699 3.1162259329134363 0.0018318186663073 0.8093817690592674 0.0411105929505971 75 O60830,O43678,Q99595,O43676,O75964,Q99623,Q9P0J0,P51970,Q9NVH1,O75306,P06576,Q9UDW1,P22695,P56134,Q86Y39,P18859,O75380,Q9NX63,P14854,Q13505 20 +Weibel palade body 0.8799641684084819 2.915429535521572 0.003551993067131 0.9599135938438998 0.0713555940596994 2 P51159 1 +Acrosomal membrane 0.873992236488488 2.8884062555843717 0.0038719942496348 0.9700155655171708 0.0757664370082598 2 P35613 1 +Transcription export complex 2 0.872797850104495 2.8829912182145883 0.0039391842249869 0.9717893235419036 0.0757664370082598 2 Q5JVF3 1 +Intrinsic component of mitochondrial inner membrane 0.6380327880995886 2.8388819264123666 0.0045271905417922 0.9834583237636408 0.0802466715643182 26 O60830,Q13505,Q9NVH1,Q99595 4 +Proton transporting v type atpase v0 domain 0.9241044855175734 2.724751467642557 0.0064349906098084 0.997079583720299 0.0881398713828309 3 Q93050 1 +Vacuolar proton transporting v type atpase v0 domain 0.9241044855175734 2.724751467642557 0.0064349906098084 0.997079583720299 0.0881398713828309 3 Q93050 1 +Mitochondrion 0.3056309443839429 2.6604744287957987 0.0078030652161633 0.9991596030878128 0.1007710136487383 609 O60830,Q99595,Q70HW3,Q9Y2C4,Q9H2D1,Q9NUJ1,Q9H773,O43676,Q567V2,O75964,P21796,Q9NS69,P35613,Q8NBX0,P00374,P45880,Q9P0J0,Q9H7Z7,P09601,Q16540,Q15165,Q9Y2W6,P36551,Q00059,Q09161,Q9UBX3,Q9NQP4,Q9Y6N5,P22695,Q4G176,Q9H061,Q9BSK2,Q969Z0,O95900,Q9Y5L4,P53007,O00264,P14854,Q7Z7H8,Q13505,O43169,Q9Y3D3,Q9UDX5,O43615,Q9Y5J9,Q9H2W6,Q04837,P46199,Q9HA77,Q9NVH1,Q9NVA1,Q709F0,P51530,P27695,Q10713,Q96A26,Q9NR28,P00367,Q9Y6C9,Q9H0B6,Q9H078,Q9UDW1,O00429,Q9BW92,Q6P4A7,Q4VC31,P18859,P04818,P12235,Q92665,Q96BK5,Q96EY7,O75879,Q8N4H5,P50542,Q5T9A4,P51970,O60313,Q96TA2,Q9BQ95,Q7KZI7,O75306,Q6DKK2,O15091,P36507 85 +Gpi anchor transamidase complex 0.8208420424007159 2.644045935484139 0.0081921537742817 0.999410483619322 0.1031529331352937 2 Q92643 1 +Organelle subcompartment 0.3098851582808483 2.6119745057725 0.0090020966873909 0.9997183219445488 0.1031529331352937 350 P24390,O15269,P30519,P49257,P83436,Q13555,P04062,P35613,Q14108,Q96CS3,Q15392,Q9Y282,P07099,P16435,O43852,P42345,P09601,Q5BJF2,Q92643,O95070,Q9Y5M8,Q6NUM9,O94874,O60725,Q96G23,Q8TBA6,Q8TCT9,O00264,Q96N66,Q70UQ0,Q15006,Q86XL3,Q6IAN0,Q14789,Q03001,P55735,Q99996,Q15800,Q12959,P37268,Q9HD20,Q16850,Q07065,Q10713,Q96KC8,O00429,Q9P2W9,Q9Y3B3,Q8NB49,P38435,P16615,O60568,P67812,Q15125,O15127,Q96HY6,Q6UWP7,A1L0T0,Q9H6U8,Q4J6C6,O14828,Q8IV08,Q8IWJ2,Q14534,P51648,Q08379,Q8N511,Q9P0I2,Q9UBF8,P63000,Q01968,Q10472,Q86YR5,Q9H3N1,P51572,P50570,Q2TAA5,Q9P260,Q12846,Q8TAT6,Q9Y5P4,P48651,P49458,Q9UM00,Q86UP2,O75122,Q06136,Q53GQ0,Q96A33 89 +Protein kinase complex 0.561382247154308 2.604701894046511 0.009195422730732 0.999763867458066 0.1031529331352937 32 P18074,Q00534,P24941,O15111,O95067,P54619,Q8IUD2 7 +Intrinsic component of mitochondrial membrane 0.5235441764475551 2.5814107478296284 0.0098397430899457 0.9998688514426428 0.1071702138953125 39 O60830,Q99595,Q9NVH1,Q13505,Q6P4A7 5 +Nata complex 0.8815329896363248 2.544035967804266 0.0109579800386776 0.999952779795233 0.1123020600233715 3 Q9BXJ9 1 +Inhibitory synapse 0.7990444908928085 2.541799672459655 0.0110283361871554 0.9999557208925024 0.1123020600233715 2 Q8N8E3 1 +Nuclear outer membrane endoplasmic reticulum membrane network 0.3178099791036951 2.5370056545028277 0.0111805148253356 0.9999614714826116 0.1123020600233715 286 Q10472,P24390,O15269,Q86YR5,P30519,P67812,Q15006,O60568,Q86XL3,P49257,Q9H3N1,Q13555,Q6IAN0,Q15125,Q03001,P55735,P51572,P35613,Q96CS3,Q14108,Q15800,Q15392,Q9Y282,Q12959,Q96HY6,Q6UWP7,Q2TAA5,P07099,P37268,P16435,O43852,P42345,P09601,Q9HD20,A1L0T0,Q5BJF2,Q16850,Q92643,Q07065,Q9H6U8,Q8TAT6,O95070,Q9Y5P4,Q9Y5M8,Q6NUM9,Q96KC8,O94874,P51571,Q8IV08,P48651,P49458,O00429,Q14534,Q96S52,Q9P2W9,Q9GZZ9,P51648,O60725,P38435,Q9UM00,Q86UP2,Q96G23,Q8TCT9,Q8N511,Q9P0I2,O00264,Q9UBF8,Q06136,Q53GQ0,Q9Y3B3,Q96N66,Q8NB49,Q96A33,Q70UQ0,P16615,P63000 76 +Tim23 mitochondrial import inner membrane translocase complex 0.9223491808679188 2.5119517840656425 0.0120065491805483 0.9999819001303842 0.1142517943075336 6 O60830 1 +Endoplasmic reticulum golgi intermediate compartment 0.4878852985975664 2.49290386837102 0.0126703144951672 0.9999901411968452 0.1180821062230015 46 Q10472,Q9Y282,P24390,Q08379,Q8N511,P80303,P09429,P51572,Q14789,Q9Y3B3,P33908,P30533,O95070 13 +Myosin filament 0.7829202747088709 2.46539772326727 0.0136861241359931 0.9999961123311044 0.1262475124381407 2 P35580 1 +Phosphatidylinositol 3 kinase complex class iii 0.7802329053448795 2.4526005046858383 0.0141827752970904 0.9999975342587608 0.1273039764188659 2 Q08AM6 1 +Striated muscle thin filament 0.8600881371448308 2.4515783646834306 0.0142231212591874 0.9999976238198148 0.1273039764188659 3 P67936 1 +Myofilament 0.8600881371448308 2.4515783646834306 0.0142231212591874 0.9999976238198148 0.1273039764188659 3 P67936 1 +Sperm annulus 0.8473715651134964 2.396299960388459 0.0165615307601905 0.9999997223727276 0.1425868934020212 3 Q15019,Q14141 2 +Ikappab kinase complex 0.8422850942694065 2.3740951761674594 0.017592015206286 0.9999998923874732 0.148627866789557 3 O15111 1 +Dynactin complex 0.8858004063645012 2.2939671226323495 0.0217923872974019 0.9999999977630378 0.1758956974718872 5 Q9UJW0 1 +Pinosome 0.816606929510149 2.2611806877072507 0.0237480704912742 0.9999999996335942 0.1829639999722039 3 Q9P2R3,Q06481 2 +Mitotic spindle microtubule 0.8146439469492238 2.25249300390641 0.024291134336829 0.999999999778432 0.1829639999722039 3 P23258 1 +Pore complex 0.8102835629497833 2.2477714859600395 0.0245907649681829 0.9999999998321488 0.1829639999722039 8 P45880,P21796 2 +Dynein complex 0.7291382087917112 2.2291548858597188 0.0258036010752995 0.9999999999454928 0.1896459786347219 12 Q9UJW0,Q13561,Q13409 3 +Golgi apparatus 0.2946061049651399 2.219759335944484 0.0264351086226852 0.99999999996967 0.1911787055592599 305 Q10472,P24390,Q86YR5,O60568,Q93050,Q6P3W7,Q14789,P50570,P04062,P51572,P33908,Q9UQB8,P31948,P35613,Q14108,Q99996,O15127,P30533,Q02818,Q7Z392,Q15392,Q9Y282,Q12959,Q9H267,Q9P260,P50542,O43852,Q9H7Z7,P54646,Q12846,O95070,Q10713,Q4J6C6,O14828,O75695,P36507,Q96PU5,O43290,P25398,Q8IV08,Q8IWJ2,O00429,Q9Y2L5,Q9P2W9,Q08379,Q8TBA6,P80303,P51159,P50897,Q9UBF8,Q92544,Q9Y3B3,Q15036,Q8NB49,P63000,Q8IUD2,Q8IY95,Q01968 58 +Transporter complex 0.4346261794848557 2.211004186937431 0.0270355471207341 0.9999999999826354 0.1939693221995532 54 Q9Y5L4,Q9P0J0,P51970,P17252,O75380,Q9Y5J9,O43676,Q9UDW1,P22695,O75381,Q86Y39,Q8NB49,Q99996,O75306 14 +Paranode region of axon 0.7285756942370886 2.2030970314579266 0.0275879103873739 0.9999999999896076 0.1963737873242997 2 Q9Y2J2 1 +Non motile cilium 0.623064010943636 2.178146079912055 0.0293951628965394 0.9999999999980664 0.2044094404497818 18 Q16181,P51159,Q96FJ2,P23258,P35613,Q9UIS9,Q15019,Q01968 8 +Golgi cis cisterna 0.7211107793371015 2.1664954907974576 0.030273344059843 0.9999999999991468 0.206456772741048 2 Q08379 1 +Calcium and calmodulin dependent protein kinase complex 0.7154374440131412 2.1385878527242252 0.0324690621538641 0.99999999999989 0.2125508464707079 2 Q13555 1 +Seh1 associated complex 0.7826604060699299 2.1098399557865335 0.034872143585177 0.9999999999999885 0.217608703782426 3 P55735 1 +Gator2 complex 0.7826604060699299 2.1098399557865335 0.034872143585177 0.9999999999999885 0.217608703782426 3 P55735 1 +Er membrane insertion complex 0.7819750270932915 2.1067605801107763 0.0351383380603427 0.999999999999991 0.217608703782426 3 Q7L5D6 1 +Microtubule bundle 0.7085697223051448 2.1047013262804453 0.0353173149712864 0.9999999999999925 0.217608703782426 2 Q7KZI7 1 +Cis golgi network 0.7222848558908234 2.095713214579221 0.0361076389019512 0.9999999999999964 0.217608703782426 11 P24390,Q08379,Q8TBA6,Q14789,Q99996 5 +Cuticular plate 0.7037921767691863 2.081061766581984 0.0374282528315474 0.9999999999999988 0.2197087049332398 2 Q01082 1 +N terminal protein acetyltransferase complex 0.8481039681632644 2.076260489164564 0.0378698654570435 0.9999999999999992 0.2200125843747547 4 Q9BXJ9 1 +Microtubule associated complex 0.4249735295240617 1.9987716567647569 0.0456330657994721 1.0 0.2530815428387902 50 Q9UJW0,Q96FJ2,Q13409,O00139,O95235,P49354,O43237,P29372,Q13561,P33176,A0MZ66,P12270,Q9H0B6,Q99661,Q9BW19,Q9NS87,Q9Y496,O60333,O15344,Q9UBN7 20 +Equatorial microtubule organizing center 0.6834876082412598 1.9799985664495872 0.0477036897659781 1.0 0.2613583972632985 2 Q9BSJ2 1 +Centriolar subdistal appendage 0.6822932218572547 1.9740242476591827 0.0483789858795495 1.0 0.263461465271764 2 O00139 1 +Endoplasmic reticulum 0.2916198458893584 1.9655390296565511 0.0493518829641252 1.0 0.2667723147108225 452 P24390,O15269,P30519,Q32P28,P49257,P55145,Q13555,P04062,Q8IXB1,Q9UQB8,P35613,Q14108,Q96CS3,Q15392,Q9Y282,P07099,P16435,O43852,P42345,P09601,Q5BJF2,P46778,Q92643,O95070,Q9Y5M8,Q6NUM9,O15173,O60506,P35573,O94874,P51571,Q08AM6,Q96S52,Q9GZZ9,O60725,Q9Y673,Q96G23,Q8TCT9,P80303,O00264,O76094,P62753,P27361,P43307,Q96N66,P61960,Q70UQ0,Q15293,Q15006,Q86XL3,Q6IAN0,Q03001,P55735,P33908,Q15800,Q12959,P37268,Q9HD20,Q9H2J4,Q16850,Q07065,Q14257,P27695,Q96KC8,P00367,O00429,Q06481,Q9P2W9,Q96EZ8,Q9Y3B3,Q8NB49,P38435,P16615,Q8IY95,Q9NUQ7,O60568,P67812,Q13017,Q15125,Q6ZXV5,Q96HY6,Q6UWP7,A1L0T0,Q9H6U8,O43681,P36507,Q9H089,Q8IV08,Q14534,P17252,P51648,P29692,Q8N511,Q9P0I2,Q9UBF8,P27635,O43390,P63000,Q10472,Q86YR5,Q9H3N1,P51572,P30533,Q02818,Q2TAA5,Q8TAT6,Q9Y5P4,O75718,P48651,P49458,Q9UBS4,Q9UM00,Q9Y4I1,Q86UP2,P29373,Q06136,Q53GQ0,Q96A33 118 +Cytoplasmic dynein complex 0.7139656417609745 1.9635943268828884 0.0495771558312148 1.0 0.2667723147108225 10 Q9UJW0,Q13409,Q96FJ2 3 +Spectrin 0.7473511592535845 1.9500118431559712 0.0511747074807786 1.0 0.2686046799041574 3 Q13813 1 +Nucleoid 0.4711970866756369 1.9431537247218476 0.0519975873708269 1.0 0.2686046799041574 34 P45880,Q12849,O00411,P34897,Q00059,P06576,Q7L8L6,P21796,Q04837,Q8IYB8,P51530,Q9NVI7,Q9Y2S7,P29372 14 +Polymeric cytoskeletal fiber 0.3074661714275375 1.9185811932265564 0.0550373575826481 1.0 0.2780419040655064 180 Q03252,Q8WUX9,Q96FJ2,Q9Y2A7,Q03001,Q14651,P50570,Q9UQB8,Q16512,Q13409,Q5M775,P04350,P23258,O95235,O00139,P67936,Q4VCS5,Q12959,P15311,O60313,Q00839,Q96JB5,Q9Y5M8,Q13561,Q7KZI7,O43663,P06753,P36507,P08670,Q9H0B6,Q92974,O00429,Q96EY1,Q9BW19,P07197,Q9NS87,Q9Y4I1,P16949,Q08379,O75122,P30622,Q9BR76,P20700,O15344,P02545,Q9BSJ2,P63000 47 +Endoplasmic reticulum golgi intermediate compartment membrane 0.5417654500119158 1.8481489274847815 0.0645808013937367 1.0 0.3051954719924729 21 Q10472,Q9Y282,P24390,Q08379,Q8N511,Q9Y3B3,O95070 7 +Cilium 0.3696302949854949 1.8425208432970437 0.0653990005539051 1.0 0.3051954719924729 93 Q16181,Q96FJ2,P04350,P35613,O00139,P23258,P57076,Q15019,P15311,Q9Y5K8,Q14141,Q10713,O75695,Q9UPT5,P17252,Q9UIS9,P51159,Q8IUD2,Q01968 19 +Nucleotide activated protein kinase complex 0.7920941840445377 1.842329898238464 0.0654269089830426 1.0 0.3051954719924729 4 P54619 1 +U7 snrnp 0.655120931621378 1.837265572272139 0.0661706996797839 1.0 0.3051954719924729 2 P62318 1 +Juxtaparanode region of axon 0.7213261648745464 1.830730951991248 0.0671407108225159 1.0 0.3065414271896687 3 Q9Y2J2,Q8IXJ6 2 +Mmxd complex 0.78840612474693 1.8267591794509173 0.067735985944338 1.0 0.3077051823803095 4 O76071 1 +Axolemma 0.7195340501792056 1.8224737878026929 0.0683831274623791 1.0 0.3090917361299539 3 Q9Y2J2,Q01082 2 +Mitochondrial permeability transition pore complex 0.7853607621014345 1.8138872948973943 0.0696950791499746 1.0 0.3103662638008723 4 P21796 1 +Pericentriolar material 0.7759840377074241 1.7741734737881525 0.0760344604640721 1.0 0.3300285457394742 4 Q9UIS9,P23258 2 +Crd mediated mrna stability complex 0.748692262182262 1.769067646378755 0.0768825863385389 1.0 0.3300285457394742 6 Q00839,P67809 2 +Proton transporting two sector atpase complex proton transporting domain 0.6746780818065197 1.7681789083704 0.0770309990608728 1.0 0.3300285457394742 10 O75964,Q9Y487,Q93050 3 +Cd40 receptor complex 0.7726117622102643 1.7598614265841028 0.0784313049402201 1.0 0.3344429229526366 4 O15111 1 +Ciliary basal body 0.5544243425859525 1.7528459040606656 0.0796284612721749 1.0 0.3363744345329258 18 O75695,P15311,Q9UPT5,P23258,Q8IUD2 5 +Proton transporting two sector atpase complex 0.5261994114091144 1.7432914781521152 0.0812827131767408 1.0 0.3401832069989524 21 P18859,Q8N511,P06576,Q9Y5K8,Q93050,O75964,Q9Y487 7 +Microvillus membrane 0.7651947764577327 1.7283308059828626 0.0839289330603421 1.0 0.3480355756263728 4 P15311 1 +9plus0 non motile cilium 0.6318888535447955 1.7193144731355678 0.0855571259980187 1.0 0.3515620086464045 12 Q15019,P51159,Q96FJ2,P35613 4 +Signal recognition particle 0.7348056557352536 1.7074415863575152 0.0877400063315185 1.0 0.3572836293860035 6 P49458,P09132,O76094 3 +Membrane protein complex 0.2849186159261564 1.6924477625105216 0.0905606321284924 1.0 0.3590649624743734 282 O60830,O15269,O43678,Q99595,P67812,Q15006,Q93050,Q8WUX9,O43676,O75964,P55735,P21796,Q9NS69,Q96CS3,Q99996,Q99623,Q9Y487,Q12959,P45880,Q9H267,Q9P0J0,Q8N4H5,P14406,P51970,O15111,Q9Y5K8,Q9NVH1,Q14254,Q99816,Q92643,Q12846,Q8TAT6,Q9Y5M8,O75306,Q9NR28,P06576,P51571,Q9UDW1,P22695,P49458,P56134,Q86Y39,Q9P2W9,P17252,P18859,P46939,Q9UNH7,Q8TCT9,Q8N511,Q9P0I2,Q9NX63,P09429,P14854,P12235,O75380,Q53GQ0,Q9Y3B3,Q13505 58 +Pole plasm 0.7526676891605796 1.6749188141327669 0.0939501616805986 1.0 0.3680407204861726 4 Q9Y2W6 1 +Secretory granule membrane 0.3722312717042505 1.6744316160268633 0.0940458035755595 1.0 0.3680407204861726 66 P30519,P07602,Q9Y5K8,O00264,Q93050,P51159,P42785,Q07065,Q06481,P35613 10 +Polar microtubule 0.6836917562723942 1.6562659579731631 0.0976679711728847 1.0 0.3741179912724058 3 Q13618,P23258 2 +Photoreceptor outer segment 0.6628586084351141 1.6309914593883743 0.1028921216372709 1.0 0.3885749859330315 9 P51159,Q01968,P35613 3 +Copi coated vesicle membrane 0.6314041331886611 1.629716158376185 0.1031615006901853 1.0 0.3885749859330315 11 Q9Y3B3,P24390 2 +Ripoptosome 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3944042185282391 2 Q14790 1 +Outer mitochondrial membrane protein complex 0.5793680082546346 1.610404600394378 0.1073095569385049 1.0 0.394490151169453 14 Q13505,Q9NVH1,Q8N4H5,Q9NS69 4 +Myosin ii complex 0.672640382317794 1.604649605134708 0.1085709381988333 1.0 0.394509019890535 3 P35579,P35580 2 +Dense core granule 0.6094356524335649 1.604073613442378 0.1086978273424021 1.0 0.394509019890535 2 Q709C8 1 +Dense core granule membrane 0.6094356524335649 1.604073613442378 0.1086978273424021 1.0 0.394509019890535 2 Q709C8 1 +Caveola 0.5657574779969265 1.5981634591508052 0.1100066036408311 1.0 0.3961990824355034 15 P35221,Q14254,O75955,P09601,P27361,Q9UNF0,Q9UBN7,Q8WTV0 8 +Postsynaptic specialization intracellular component 0.7289583076908973 1.5733371816308428 0.1156407642283348 1.0 0.4021099798715425 4 Q9UQB8 1 +Postsynaptic density intracellular component 0.7289583076908973 1.5733371816308428 0.1156407642283348 1.0 0.4021099798715425 4 Q9UQB8 1 +Copi coated vesicle 0.6044117012000644 1.5713735230058647 0.1160959123301688 1.0 0.4021099798715425 12 Q9Y3B3,P24390 2 +Mcm complex 0.7037773713773888 1.5688271582423774 0.1166882184179809 1.0 0.40261889102998 6 Q14566,P33992,P25205 3 +Respirasome 0.3980577370643869 1.562277855538208 0.1182225464195858 1.0 0.405413180841451 44 Q6DKK2,O43678,Q9P0J0,P51970,O75380,P14854,O43676,Q9UDW1,P22695,Q86Y39,O75306 11 +Plasma membrane raft 0.4918688888000239 1.5558641599769791 0.1197403974387913 1.0 0.405413180841451 22 P35221,Q14254,P15311,O75955,P09601,Q9UBN7,P27361,Q9UNF0,P17252,Q8WTV0 10 +Postsynaptic density membrane 0.6960309307300587 1.5340494751283966 0.1250174817001688 1.0 0.4185770498405651 6 Q99996 1 +Post mrna release spliceosomal complex 0.693273542600902 1.5216559337137645 0.128095314543517 1.0 0.4253532394548991 6 Q9BZJ0,Q9HCS7,P16383,Q9UBB9,P52272 5 +Sperm principal piece 0.5921170498656352 1.5148174667762595 0.1298186358583439 1.0 0.4267492611488834 2 Q9BW83 1 +Prefoldin complex 0.7143694141100073 1.5105571153139956 0.1309013271315808 1.0 0.427201443057578 4 P61758,Q9NQP4 2 +Ampa glutamate receptor complex 0.6511350059737072 1.5038025415625602 0.1326322165918281 1.0 0.4312932510755849 3 Q92796,Q15334 2 +Basement membrane 0.6822399278323701 1.4719959759694674 0.1410219642302483 1.0 0.4496959720558675 6 Q03001 1 +Intrinsic component of organelle membrane 0.3405407893222971 1.4657789083742283 0.1427085288669012 1.0 0.4496959720558675 106 O60830,Q99595,Q15006,Q86XL3,Q15125,P51572,P42892,Q9Y282,Q9NVH1,O95070,Q9HC21,Q5SNT2,Q6P4A7,Q9UM00,Q86UP2,Q8TCT9,Q9P0I2,Q9NX63,P12235,Q13505 20 +Transcription preinitiation complex 0.6427718040621176 1.4644648945108083 0.1430669681874148 1.0 0.4496959720558675 3 P19447,Q00403 2 +Microtubule cytoskeleton 0.2689684331772218 1.4341507180895978 0.1515292571050102 1.0 0.4691179740511274 376 Q9UJW0,Q16181,P34897,O76071,Q6UVJ0,Q9UQB8,Q16512,P49354,O95067,Q99816,Q9UJX4,Q9Y2S7,Q13561,Q9Y5M8,Q3YEC7,O75695,O43663,P08670,Q8WYA6,Q92974,Q9BTE7,Q9BW19,Q9NS87,P16949,P30622,P53985,P54725,Q8IUD2,P51608,Q8WUX9,Q9UNZ2,Q03001,Q13409,Q5M775,Q99996,O95235,Q15019,Q12959,P25205,Q00534,P15311,Q9Y5K8,Q5T4S7,Q14141,Q5VU43,Q14674,P27695,Q9NZM3,Q13464,A0MZ66,O14530,O60763,Q9H0B6,Q15650,P17987,O00429,P35579,Q99570,Q92547,O15344,Q86UY6,Q9P0V9,Q9UBN7,Q9Y5Y2,Q96BK5,Q6IN85,Q96FJ2,P04350,O60313,Q9UNN8,Q6DKK2,P24941,P36507,Q9UPT5,Q5SNT2,Q14166,P17252,P83916,P18074,Q08379,O75330,Q13813,Q9UQE7,Q8N8E3,P50570,P23258,O00139,Q96CT7,P62081,Q00839,Q96JB5,Q9Y3D8,Q12873,P12270,O14757,P16104,Q9UIS9,O75122,Q9BSJ2,Q8N1F7 100 +Cyclin dependent protein kinase holoenzyme complex 0.5341303340841627 1.410891703592153 0.1582765488270165 1.0 0.4813731106763348 15 O95067,Q00534 2 +Smc5 smc6 complex 0.6302270011947336 1.4053646372123745 0.1599128766666422 1.0 0.4818708016888152 3 Q96SB8,Q96MG7 2 +Rough endoplasmic reticulum 0.4110844925819799 1.3917356842458384 0.1640024522453735 1.0 0.4893010456429627 33 P04844,P04843,O60568,Q8TCT9,P51571,Q9UBF8,Q5BJF2,P49458,Q07065,Q9UQB8,P30533,Q96A33,P62266,Q9Y5M8 14 +Septin cytoskeleton 0.6616603686413556 1.379138418435791 0.1678520805765972 1.0 0.4921144168863499 6 Q9P0V9,Q16181,Q15019,Q14141 4 +Golgi membrane 0.3290608281018281 1.3561151382586645 0.1750625370011984 1.0 0.4965296158562982 117 Q10472,P24390,Q86YR5,Q14789,P51572,P33908,P35613,Q14108,Q15392,Q9Y282,Q9H7Z7,O95070,Q10713,Q8IV08,Q9P2W9,Q08379,Q8TBA6,Q9UBF8,Q9Y3B3,Q8IUD2 20 +Outer membrane 0.3325322949225546 1.3544647308583646 0.1755881581924983 1.0 0.4965296158562982 81 P45880,Q8N4H5,O00264,Q9NVH1,P09601,Q9Y6C9,O60313,Q9NX63,O00429,P21796,Q9NS69,Q13505,O43169 13 +Mcrd mediated mrna stability complex 0.6663924419861189 1.350386132601239 0.1768921566919168 1.0 0.4965296158562982 5 Q9H074,Q14103 2 +Respiratory chain complex iii 0.6366568067945892 1.346207172566438 0.1782357125582638 1.0 0.4965296158562982 7 P22695 1 +Pseudopodium 0.618648898047904 1.346198184767664 0.1782386103407574 1.0 0.4965296158562982 8 P27361,P26038,P12814 3 +Collagen containing extracellular matrix 0.4113259508542346 1.3447671726365291 0.178700434473733 1.0 0.4965296158562982 31 Q13043,P07602,Q32P28,Q03001,Q12959 5 +Caspase complex 0.6758881210847278 1.3442720062183573 0.1788604444390977 1.0 0.4965296158562982 4 Q92643 1 +Intrinsic component of golgi membrane 0.6179600802613897 1.3428698297037427 0.179314127236267 1.0 0.4965296158562982 8 Q9Y282 1 +Microtubule organizing center 0.2798771316055888 1.3354831666212346 0.1817182610845915 1.0 0.4977979030923356 213 Q9UJW0,Q6IN85,Q8N8E3,Q96FJ2,Q9UNZ2,Q6UVJ0,P50570,Q16512,Q13409,Q5M775,Q99996,P23258,O00139,Q96CT7,P25205,Q00534,P15311,Q9Y5K8,Q5T4S7,O95067,Q5VU43,Q14674,P62081,Q99816,Q00839,Q96JB5,Q9UNN8,P27695,Q13561,Q9NZM3,Q9Y3D8,Q6DKK2,Q3YEC7,O75695,Q13464,Q12873,P24941,O14530,P08670,O60763,O14757,P16104,Q15650,Q8WYA6,Q9UPT5,Q14166,P17252,Q9BW19,Q9UIS9,Q9NS87,O75122,P30622,Q86UY6,P54725,O75330,Q9BSJ2,P53985,P51608,Q8IUD2,Q8N1F7 60 +Cortical cytoskeleton 0.3717210032183234 1.3169729204501373 0.1878477017178652 1.0 0.5084261148291921 45 Q05682,P35241,Q01082,P46939,P35240,Q14254,P15311,P61160,P47755,Q14651,Q13813,Q9NS86,Q8IUD2,P12814,P67936 15 +Proton transporting v type atpase complex 0.5830122573578741 1.3022879612139289 0.1928179655116424 1.0 0.5187721453051332 10 Q9Y5K8,Q9Y487,Q93050 3 +Organelle envelope lumen 0.3974495712461028 1.2993995507135745 0.1938068457980279 1.0 0.5198854261169653 34 Q9NR28,Q9Y5L4,P36551,P51970,Q9Y5J9,O60313,Q9H078,Q6FI81,Q4VC31 9 +Supramolecular polymer 0.2766645868788779 1.263230774031613 0.2065062563052659 1.0 0.545478055201749 222 Q05682,Q9UJW0,P35580,Q03252,P49257,Q8WUX9,Q96FJ2,Q9Y2A7,Q03001,Q14651,P50570,Q8WXH0,Q9UQB8,Q16512,Q13409,Q5M775,P04350,P23258,O95235,Q8NEZ5,P12814,P67936,Q4VCS5,Q12959,O00139,P15311,Q16527,O60313,Q5VU43,Q00839,O43237,Q96JB5,Q9Y5M8,Q13561,P29372,Q7KZI7,O43663,Q01082,P33176,A0MZ66,P06753,P36507,Q96FZ7,P08670,Q96AC1,Q9H0B6,P17987,Q92974,O00429,Q99661,Q96EY1,P35579,Q9NYL9,Q9BW19,P07197,Q9P253,Q9NS87,Q9Y4I1,P16949,Q9Y496,Q08379,O75122,P30622,Q9BR76,O43707,P20700,O15344,Q9UBN7,P02545,Q9BSJ2,P63000,O43819 72 +Actin cytoskeleton 0.3066927189772739 1.2598094384609375 0.2077381141087091 1.0 0.545478055201749 141 Q05682,Q16181,P35580,Q9UJW0,P35240,Q96FJ2,Q5T1M5,Q14651,Q9UQB8,Q16512,Q5M775,Q15019,P67936,Q4VCS5,Q14254,P15311,P61160,O75607,P27695,Q13561,Q7KZI7,Q13576,P06753,Q9UJZ1,P35241,Q9Y4I1,P46939,Q9BR76,Q9UL03,P59998,P63000,Q13813,Q9NS86,Q9BTX1 34 +Actin filament 0.3894880065626284 1.2569324271971052 0.2087781051988995 1.0 0.545478055201749 35 Q7KZI7,Q9Y4I1,P15311,P06753,Q9BR76,Q9Y2A7,Q14651,Q16512,Q96EY1,Q5M775,P63000,P67936,Q4VCS5 13 +Vacuolar membrane 0.3218455814654755 1.253662938450037 0.209964544210667 1.0 0.5463629498268916 118 P07602,Q8TDB6,Q8NCG7,Q9Y5K8,Q93050,Q8WUX9,Q9H0B6,P42785,P04062,Q9P2R3,P55735,Q07065,Q96EE3,Q8NB49,Q14108,Q9Y487,Q8WTV0 17 +Golgi stack 0.4070417155165203 1.244146264309663 0.2134457364783302 1.0 0.5497291902461837 29 Q10472,Q08379,Q8TBA6,Q14789,Q99996,Q10713,Q01968 7 +Filopodium 0.3975235719727213 1.2276659406689987 0.2195723970408822 1.0 0.5555588105253008 31 P35241,Q13576,Q9Y4I1,P35240,P15311,P51116,Q9UQB8,P26038 8 +Centrosome 0.287362067249037 1.2261018738166316 0.2201603408041366 1.0 0.5555588105253008 166 Q9UJW0,Q8N8E3,Q96FJ2,Q6UVJ0,P50570,Q13409,P23258,O00139,Q99996,P25205,Q00534,Q9Y5K8,Q5T4S7,O95067,Q5VU43,Q14674,P62081,Q00839,Q96JB5,Q9UNN8,P27695,Q13561,Q9NZM3,Q9Y3D8,Q6DKK2,Q3YEC7,Q12873,P24941,O14530,O14757,P16104,Q15650,Q8WYA6,Q9UPT5,P17252,Q9UIS9,Q9NS87,P30622,Q86UY6,P54725,O75330,Q9BSJ2,P53985,P51608,Q8IUD2,Q8N1F7 46 +Glycogen granule 0.5833333333333222 1.1841311150096652 0.2363611649404038 1.0 0.5774878192057433 3 P62136,P49327 2 +Cd95 death inducing signaling complex 0.5829788386303763 1.182461166470343 0.2370227654445169 1.0 0.5775433422152111 3 Q14790 1 +Membrane microdomain 0.3301329603587224 1.169638043646989 0.242146660726338 1.0 0.5884424228403484 67 P09601,P50897,P21796,P35613,Q8WTV0,Q12959 6 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6236185719931824 1.1612583610712246 0.2455368473610624 1.0 0.5950812600922263 5 O75964 1 +Exocyst 0.6229776125384598 1.1584294954252394 0.2466888082291425 1.0 0.5953005881370709 5 Q8IYI6,Q9UPT5 2 +Mitochondrial large ribosomal subunit 0.3911510528471381 1.1547073774314955 0.2482102773996988 1.0 0.5953005881370709 30 Q567V2,Q7Z7H8,Q16540 3 +Proton transporting atp synthase complex 0.5396336893236076 1.1461953567151588 0.251714328710513 1.0 0.6015196000784285 11 P18859,P06576,P56134,O75964,P25705 5 +Sin3 type complex 0.6095074845031134 1.143451551138445 0.2528511593250031 1.0 0.6015196000784285 6 Q9UBU8 1 +Cytoplasmic region 0.3271410709286043 1.1404918497917371 0.2540814462848726 1.0 0.6027664830923959 68 Q16181,O75122,Q14254,O60313,Q00839,Q03001,Q8IUD2,Q9UQB8,P04350,Q10713,P17252,P27695,Q15019 13 +Actomyosin 0.3985933751635511 1.13641285798167 0.2557838170105087 1.0 0.6027664830923959 28 Q9UJW0 1 +Neuromuscular junction 0.4683504981284073 1.1357949289190106 0.2560423998976548 1.0 0.6027664830923959 17 O43760,P46939,O14795,Q15650,Q96EY1,P17252,Q12959 7 +Neuron projection membrane 0.6068307096749171 1.1313836256879417 0.2578936603204069 1.0 0.6030741148191407 6 Q12846,Q9Y2J2,Q01082 3 +Golgi associated vesicle membrane 0.4460361226252492 1.1232237727352865 0.2613424685540582 1.0 0.6089010092084243 19 Q9Y3B3,P24390 2 +Kinesin complex 0.463759401730224 1.1069800873621418 0.2683025376885051 1.0 0.6183742385221128 17 Q9Y496,P33176,Q9H0B6,Q99661,O00139,Q9BW19,O95235,Q9NS87 8 +Phagocytic cup 0.6207754426440633 1.105948971629848 0.2687486066266729 1.0 0.6183742385221128 4 P50570,Q9Y5X3 2 +External encapsulating structure 0.375561597231647 1.1057641318206388 0.268828623605299 1.0 0.6183742385221128 34 Q13043,P07602,Q32P28,Q03001,Q12959 5 +Dendrite cytoplasm 0.5173544281273798 1.0972229618274911 0.2725439379098491 1.0 0.6237461262544395 12 P33176,Q14254,Q00839,P23246,Q9UQB8 5 +Microbody membrane 0.4113863325643463 1.0702098364300563 0.2845248677684058 1.0 0.6451522828507862 24 P50542,P36507,Q6IAN0,O75381,P51648 5 +Prp19 complex 0.5375743348612584 1.0697053712942666 0.2847519478511766 1.0 0.6451522828507862 10 Q9BZJ0,Q9HCS7,Q99459 3 +Transcription factor tfiih holo complex 0.6113742718437615 1.065508176939152 0.2866460272768019 1.0 0.6478200216455722 4 P18074,P19447 2 +Dna replication preinitiation complex 0.521825595722414 1.0523915308977865 0.2926199526906674 1.0 0.6580309383889635 11 P33992,Q9UBD5,Q14566,Q9BRT9,P25205 5 +U2af complex 0.551657691202543 1.0354869423882065 0.3004415613649058 1.0 0.6706152382070985 3 Q01081 1 +Neuron projection cytoplasm 0.3670746210894538 1.0309147577550968 0.3025807953978274 1.0 0.6708492791024854 34 Q14254,O60313,Q03001,Q9UQB8,P27695 5 +Neuron projection terminus 0.4673534089895576 1.0133939822607665 0.3108720126329471 1.0 0.6816854372711314 15 Q05682,O14795,Q9UQB8,Q14141 4 +Cell trailing edge 0.5801929882634347 1.0117597740708917 0.3116529276739235 1.0 0.6816854372711314 6 P15311,P26038,P35579,Q14254 4 +Transcription factor tfiid complex 0.5488027063079132 1.0094284863172978 0.3127691825294305 1.0 0.6816854372711314 8 P18074,P35269,Q00403,Q92759,P19447 5 +Cell cortex 0.3087322745058638 1.0047522048475106 0.3150161834763141 1.0 0.682912781445055 106 Q05682,Q16181,P35580,Q9UJW0,Q86YR5,P35240,Q03001,Q14651,Q15019,P67936,O14795,Q14254,P15311,P61160,Q14141,Q9UPT5,P35241,O75122,P46939,Q9P0K7,Q8IUD2,P63000,Q13813,Q9NS86 24 +Nadh dehydrogenase complex 0.407352692469573 0.9985287091046022 0.3180230503038777 1.0 0.686140423567316 23 Q9P0J0,P51970,O75380,O43676,Q86Y39,O75306 6 +Presynaptic active zone cytoplasmic component 0.5757296116189329 0.9918274725102556 0.3212816937528435 1.0 0.6899739930732918 6 Q8IUD2 1 +Cytochrome complex 0.4453382957688357 0.991735878965096 0.3213263839423184 1.0 0.6899739930732918 17 P22695,P14854 2 +Organellar ribosome 0.3392129901491634 0.9874011008831404 0.3234460448988616 1.0 0.6901560559502009 45 Q567V2,Q7Z7H8,Q9Y3D3,Q16540 4 +Cation transporting atpase complex 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.6978094446219552 3 P54709,P05023 2 +Atpase dependent transmembrane transport complex 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.6978094446219552 3 P54709,P05023 2 +Sodium potassium exchanging atpase complex 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.6978094446219552 3 P54709,P05023 2 +Actin filament bundle 0.3774529836150765 0.9670092657883732 0.3335394016640181 1.0 0.6995814828405391 28 Q16181,Q9UJW0,P06753,Q9BR76,Q14651,P67936 6 +Plasma membrane region 0.2597188895095776 0.9572522002615074 0.3384399753198135 1.0 0.7049533126477221 189 Q16181,P35240,Q9BY67,Q03001,P50570,P40855,Q9UQB8,P35613,O95630,Q99996,P08183,Q8WTV0,Q15019,Q12959,Q14254,P15311,P09601,Q14141,Q12846,Q9NWH9,O75695,P36551,O00429,Q06481,P17252,P35241,O75122,P46939,Q8NCG7,P26038,P51159,Q9UNF0,P63000,P53985,Q8IUD2,Q01968 36 +Small ribosomal subunit 0.3324120667578036 0.9518068549705204 0.3411949448885241 1.0 0.708451412355553 47 P62841,P82933,P08865,P61247,Q7Z478,P62854,P25398,P62081,P62753,P15880,Q92552,P62266,Q9Y3D3,P46782 14 +Death inducing signaling complex 0.5833971646526653 0.946008773214784 0.3441441114801749 1.0 0.708451412355553 4 Q14790,P49327 2 +Specific granule membrane 0.4468430810348723 0.9446815406126858 0.3448214838898709 1.0 0.708451412355553 16 Q9Y5K8,O00264,P30519 3 +Endoplasmic reticulum lumen 0.3142083611907506 0.9276537277207229 0.3535872182157678 1.0 0.7182985286900091 59 Q86UP2,Q14257,Q15293,O60568,O43681,O75718,Q32P28,O43852,P55145,Q07065,P30533,Q06481,Q02818,Q9UBS4 14 +Ruffle 0.3118510623460127 0.9124474140875406 0.3615332396432906 1.0 0.7246697309036246 61 P35240,Q9Y2A7,P50570,Q9UQB8,Q16512,P12814,Q4VCS5,P51790,Q00534,P15311,Q10713,Q13464,P19174,Q92974,Q06481,Q9Y4I1,O75122,P30622,Q9UNF0,P63000 20 +Microtubule 0.2919742966398317 0.9081274764499806 0.3638108751900928 1.0 0.7275535903612947 132 Q8WUX9,Q96FJ2,Q03001,P50570,Q9UQB8,Q13409,P04350,P23258,O00139,Q12959,O60313,Q00839,Q96JB5,Q13561,Q9Y5M8,O43663,P36507,Q9H0B6,Q92974,O00429,Q9BW19,Q9NS87,P16949,Q08379,O75122,O15344,Q9BSJ2 27 +Apical plasma membrane 0.3361993189498791 0.906106760842064 0.3648793471936142 1.0 0.7275535903612947 41 P35241,P36551,P15311,P51159,P53985,P08183,Q12959 7 +Neuron spine 0.3591615914565885 0.9036007105460676 0.3662071643855866 1.0 0.7275535903612947 31 Q15075,P51116,Q9UQB8,P63000,P17252,P27695 6 +Nuclear pore outer ring 0.5152225103698765 0.9006003005088166 0.3678008747733536 1.0 0.7275535903612947 9 P55735 1 +Microbody 0.3151234263023185 0.8914862063505408 0.3726683882798469 1.0 0.7339699847603086 54 P50542,P36507,P08670,O15254,Q6IAN0,Q13907,Q15126,Q08426,O00429,O75381,P40855,Q709F0,Q9BQG2,P51648 14 +Blood microparticle 0.4348770235693344 0.8726837253070958 0.3828354908140212 1.0 0.7368855706380545 16 P38435,P04062 2 +Ficolin 1 rich granule membrane 0.4254275455500633 0.8683439412322113 0.3852060737391503 1.0 0.7378136659589066 17 P42785,Q93050,Q5T9A4 3 +Vacuole 0.2580461642496203 0.8657623734573273 0.3866204871134402 1.0 0.7378136659589066 212 Q93050,Q8WUX9,P04062,P55735,Q9UHG3,Q14108,Q9Y487,Q8WTV0,P07602,Q9Y5K8,Q9H7Z7,Q5BJF2,Q07065,Q15165,P27695,Q8TDB6,Q9H0B6,P42785,Q8IW92,Q8NCG7,P51159,P50897,Q9P2R3,Q96EE3,Q8NB49,P38435 26 +Endocytic vesicle membrane 0.3370278981913521 0.8647842972052483 0.3871571914178422 1.0 0.7378136659589066 39 Q93050,P50570,Q06481,Q14108,Q9Y487,Q8WTV0,Q01968 7 +Condensed chromosome centromeric region 0.2965631483943179 0.8638348127357943 0.3876786408523016 1.0 0.7378136659589066 79 Q9UJW0,Q9BZD4,Q96BK5,Q8WUX9,Q14141,P55735,Q96EE3,Q15019,Q13561 9 +Proton transporting atp synthase complex coupling factor f o 0.5308372498948687 0.8558586671720699 0.3920759598257475 1.0 0.7430538106550855 7 P18859,P56134,O75964 3 +Myosin complex 0.4946369822517439 0.8529986012212917 0.3936600798987111 1.0 0.7444952138670184 10 Q9Y4I1,P35580,O94832,Q96FJ2,P35579 5 +Actin based cell projection 0.323323318291278 0.8430226550135761 0.3992157735562638 1.0 0.7534260110539927 46 P35241,Q13576,Q9Y4I1,P35240,P15311,Q14651,P51116,Q9UQB8,P26038 9 +Ribosomal subunit 0.2922361986892555 0.836651416909253 0.4027885351093849 1.0 0.7547702152910102 123 P62841,P61247,Q9H2W6,P62854,Q9P015,Q567V2,Q7Z478,P61254,Q16540,P62081,P46778,Q96CB9,P50914,Q13084,P82933,P08865,P25398,P84098,P62917,P51116,Q96A35,P62899,P62266,P62750,P46782,P61513,Q02543,P62753,P15880,Q7Z7H8,Q92552,P46776,P27635,Q9Y3D3 34 +Intraciliary transport particle 0.4589429680501645 0.8306413289753507 0.4061762798454646 1.0 0.7547702152910102 2 Q9BW83 1 +Intraciliary transport particle b 0.4589429680501645 0.8306413289753507 0.4061762798454646 1.0 0.7547702152910102 2 Q9BW83 1 +Respiratory chain complex iv 0.4671835647983489 0.8273475970513641 0.4080400731862519 1.0 0.7547702152910102 12 P22695 1 +Cell division site 0.3537726455644626 0.810357069150805 0.4177349842863127 1.0 0.7577126470689651 29 P35241,Q16181,P35580,P35240,Q14141,Q16512,O95630,P35579,Q9BSJ2,O95235,Q15019 11 +Cleavage furrow 0.3897109204937268 0.8067377082807474 0.419817614193428 1.0 0.7577126470689651 21 P35241,Q16181,P35580,P35240,Q14141,Q16512,O95630,O95235,Q15019 9 +Large ribosomal subunit 0.293809798664119 0.8048276487090098 0.420919144237541 1.0 0.7579898533680022 77 Q9P015,P50914,P61513,P84098,Q9H2W6,P61254,Q16540,Q567V2,P46778,P62917,Q7Z7H8,Q96CB9,Q96A35,P51116,P27635,Q02543,P62899 17 +Eukaryotic translation initiation factor 2b complex 0.5287052042426101 0.7851450907103164 0.4323685050700496 1.0 0.7698674825896996 6 Q9NR50,Q13144 2 +Pcg protein complex 0.4906657819230815 0.7823709256068494 0.4339966154305774 1.0 0.7698674825896996 9 Q14157,P25490 2 +Golgi apparatus subcompartment 0.2910289987829605 0.7813426728212518 0.4346009783752045 1.0 0.7698674825896996 85 Q10472,O14828,Q08379,O60568,Q9P260,Q8TBA6,Q8IWJ2,Q14789,P50570,P04062,P51572,Q8NB49,Q99996,O15127,Q4J6C6,P63000,Q10713,Q01968 18 +Platelet alpha granule 0.435072267987751 0.7785452336565327 0.4362476509808723 1.0 0.7698674825896996 14 Q8NBX0,Q06481 2 +Phosphatidylinositol 3 kinase complex 0.4950751612601416 0.7761771101553302 0.4376444193058304 1.0 0.7698674825896996 3 Q08AM6 1 +Immunological synapse 0.4264005717263607 0.7742041161468369 0.4388100945519992 1.0 0.7700988520943888 15 P15311,O15400,P35579,Q9UJZ1,Q12959 5 +Fibrillar center 0.300999406021979 0.7696214181852866 0.4415244961763609 1.0 0.7703115140828785 57 Q9Y5L4,O43615,Q15233,P15311,Q16540,O75381,Q8WXF1,Q5M775,P29692 9 +Microvillus 0.4005937825695786 0.7684036223639416 0.442247428992272 1.0 0.7703115140828785 18 P35241,P26038,P15311 3 +Paraspeckles 0.5238729560789172 0.7643709011886672 0.4446462443820798 1.0 0.7715167081024954 6 Q15233 1 +Basal part of cell 0.3073192040733936 0.7296541949693522 0.4656015862711165 1.0 0.79301957684628 49 Q14254,P15311,Q9BY67,P26038,Q03001,Q12846,P42785,P35613,P53985,Q9NWH9,Q12959 11 +Transport vesicle 0.2871210667595053 0.7187729318393613 0.4722808381689161 1.0 0.7966866957372462 88 P24390,O43760,Q8TBA6,P51159,P50897,Q14141,P55735,O00429,P27695,Q15019 10 +Risc loading complex 0.4812683851716548 0.7150564008093052 0.4745741930582507 1.0 0.7981482831619828 3 O75569 1 +Polysome 0.3074365798824581 0.7143606829297388 0.4750041773685252 1.0 0.7981482831619828 48 Q96EZ8,P08670,Q02543,P62753,P62917,P51116,O43347,P62899,P61758,Q9Y295 10 +Replisome 0.4449880486216805 0.7114431139804934 0.4768096901346808 1.0 0.7996956584077021 12 P28340,P15927,P35244,Q9Y2S7,P25205 5 +Condensed chromosome 0.2842778807583254 0.6904927561270523 0.4898843637833372 1.0 0.8130230169153718 118 Q9UJW0,Q96BK5,Q9UQE7,Q8WUX9,P55735,P23258,Q15019,Q9BZD4,P26583,Q14141,Q00839,Q8IWS0,Q13561,P24941,P12270,O14757,P16104,O75122,P09429,P54132,Q96EE3 21 +Main axon 0.4488679715629992 0.6782866125078737 0.4975899852838283 1.0 0.8184877544032982 11 Q9Y2J2,Q01082,Q15334,Q8IXJ6,P04350,Q12959 6 +Cytosolic small ribosomal subunit 0.3299572065099568 0.6770072504324034 0.4984013541526133 1.0 0.8184877544032982 32 P62841,P08865,P61247,Q7Z478,P25398,P62081,P62753,P15880,P62266,P46782 10 +Trapp complex 0.5167598231058372 0.6710781570502891 0.5021707411177332 1.0 0.8186906877648641 4 Q9Y2L5 1 +Neuron projection 0.2494853956206571 0.6703646447581318 0.5026253669352871 1.0 0.8186906877648641 227 Q05682,P35240,Q15075,Q9BY67,Q13555,Q5T1M5,Q03001,Q14651,P50570,Q9UQB8,Q16512,P35613,P04350,Q99996,Q99623,Q15019,Q12959,O14795,Q14254,P21964,P42345,O60313,P54646,Q14141,Q00839,Q12846,Q96F07,P27695,Q13561,Q7KZI7,P12277,O94874,P08670,P51116,Q9UPT5,P17252,P07197,Q9Y4I1,P16949,Q96EZ8,O00264,P51159,P50897,P62753,P63000,Q01968 46 +Anaphase promoting complex 0.4648157662167675 0.661339008626878 0.5083949303768154 1.0 0.8251149318862497 9 Q9H1A4,Q9UJX4,Q9UJX2,Q9UJX5 4 +Protein acetyltransferase complex 0.3286004713605156 0.6528301484358795 0.5138657850821526 1.0 0.8265741453990497 31 Q09472,Q9BXJ9,Q96EZ8,Q9UBU8,Q9NR33,Q92993,P41227 7 +Golgi associated vesicle 0.3330687429180284 0.6474355979751997 0.5173500630536574 1.0 0.8282182911798849 29 Q8N511,Q9Y3B3,P24390 3 +Leading edge membrane 0.3075388578798212 0.6442803176424194 0.5193936764225286 1.0 0.8282182911798849 42 P51790,Q9Y2J2,O75122,Q01082,P35240,P15311,Q9Y2A7,P50570,Q12846,Q92974,Q9UNF0,Q06481,Q16512,P63000 14 +Vesicle membrane 0.245860219220238 0.6315726282674717 0.5276661770559206 1.0 0.8313153592509621 260 P24390,P30519,Q15075,Q93050,Q8WUX9,Q6P3W7,P50570,P55735,P42892,P35613,Q14108,O15127,Q9Y487,Q8WTV0,Q9NZC3,Q9H267,Q5T9A4,Q14254,P07602,Q9Y5K8,Q07065,O14828,Q8TDB6,Q8IV08,P42785,O00429,Q06481,O43760,Q9UNH7,Q8N511,O00264,P51159,Q9UJ41,Q9Y3B3,Q9P2R3,Q9UNF0,Q15036,Q8NB49,P63000,Q01968 40 +Ciliary transition zone 0.4994075596553963 0.6308512667181895 0.5281377787872774 1.0 0.8313153592509621 5 Q15019 1 +Emc complex 0.4915391822138414 0.6286252818790723 0.5295944048095571 1.0 0.8313153592509621 6 Q15006 1 +Endosome 0.2473587865232985 0.6284828735721321 0.5296876625315865 1.0 0.8313153592509621 222 P35240,Q15075,Q93050,Q8WUX9,Q6P3W7,P50570,P42892,P30533,P23258,P35613,Q14108,O95630,O15127,Q9Y487,Q9H267,Q9P260,Q14254,P07602,P15311,P27695,O14828,P24941,Q8TDB6,Q96PU5,P36507,Q9UKS6,Q8IV08,Q06481,Q9UNH7,P09429,P51159,Q9UBF8,Q9UJ41,Q92544,Q9P2R3,Q9UNF0,Q15036,Q8NB49,P63000,Q8IY95,Q01968 41 +Lateral element 0.5007295301768989 0.6082637439151369 0.5430125632801919 1.0 0.8471104866519856 4 Q9UQE7 1 +Proton transporting atp synthase complex catalytic core f 1 0.500173686959388 0.606116853761656 0.5444371601159332 1.0 0.8471104866519856 4 P06576 1 +Exocytic vesicle 0.3098494534718474 0.6006148180094925 0.548096566118111 1.0 0.8498787234490092 38 O43760,P50897,Q14141,O00429,P27695,Q15019 6 +Cytosolic ribosome 0.2755502772500204 0.5940202464503601 0.552498571405565 1.0 0.8510322960631851 79 P62841,P61247,P62854,Q7Z478,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P51116,P62266,P62899,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635 24 +Nuclear pore nuclear basket 0.4586354352786553 0.593859411822016 0.5526061479967805 1.0 0.8510322960631851 8 Q5JVF3,O60318 2 +Coated vesicle 0.2770125305231187 0.5907448202015203 0.5546914121289546 1.0 0.851343016238667 87 Q9Y282,P24390,Q08379,Q8N511,P51159,Q6P3W7,P51572,Q9Y3B3,P55735,P50570,P42892,O95070,Q14108,Q01968 14 +Mib complex 0.4485186691432052 0.587501883427462 0.5568666859044824 1.0 0.852951851566029 9 Q13505,Q9NVH1 2 +Phagocytic vesicle membrane 0.3474745558254333 0.581330619042868 0.5610176481203721 1.0 0.8533216236062571 23 Q93050,P50570,Q06481,Q9Y487,Q01968 5 +Myelin sheath 0.4175352342675238 0.5732879424071985 0.5664497480703199 1.0 0.8563053047751993 12 P04350,Q12959 2 +Microtubule minus end 0.4435483870967572 0.5550092702865648 0.5788883196262504 1.0 0.864983538747323 3 Q14980,Q15018 2 +Ribose phosphate diphosphokinase complex 0.4396654719235201 0.539244153517806 0.5897183977207627 1.0 0.8782626549251557 3 Q14558,O60256 2 +Cell leading edge 0.2727314172842152 0.5332831452280979 0.5938375932509912 1.0 0.8829354853327498 120 P35580,P35221,P35240,Q9Y2A7,Q03001,P50570,Q8IYI6,Q9UQB8,Q16512,P23258,P12814,Q4VCS5,P51790,Q00534,Q14254,P15311,P61160,Q12846,Q10713,Q13576,Q13464,Q01082,P19174,A0MZ66,O60749,P08670,Q92974,Q06481,P35579,P35241,Q9Y4I1,Q9Y2J2,O75122,P30622,Q9BR76,Q9UBN7,Q9UNF0,P63000 38 +Ribosome 0.2629677103734901 0.5310317467699723 0.5953967798624713 1.0 0.8829354853327498 140 P62841,P61247,Q9H2W6,P62854,Q9UHB9,P82664,Q567V2,Q9P015,Q7Z478,P20290,P61254,Q16540,P62081,P46778,Q96CB9,P18621,P50914,P27695,Q13084,P82933,P08865,P25398,P84098,P62917,P51116,Q96A35,P62899,P62266,P62750,P46782,P61513,Q02543,P62753,P15880,Q7Z7H8,Q92552,P46776,P27635,Q15637,Q9Y3D3 40 +Trna splicing ligase complex 0.473307651735269 0.529014059691108 0.5967956966743149 1.0 0.8829354853327498 5 Q8NCA5,Q52LJ0 2 +Site of dna damage 0.2885252257719467 0.52880845251123 0.5969383336173832 1.0 0.8829354853327498 48 Q93034,Q13185,P49959,Q7Z7L1,P61160,P15927,P09874,O94874,O95251,Q92747,P16104,P35244,P83916,Q68E01,Q9NWY4,P02545,Q9UNS1,P59998,Q14241 19 +Chromosome centromeric region 0.2740358574540304 0.5201221818676653 0.6029784188672025 1.0 0.8863292530991074 101 Q9UJW0,Q9BZD4,Q96BK5,Q9UQE7,O75122,P12270,Q8WUX9,Q14141,Q00839,P55735,Q96EE3,Q15019,P83916,Q8IWS0,Q13561 15 +Golgi cisterna 0.3661291400443692 0.5177187723666709 0.6046544986354254 1.0 0.8869703164060792 17 Q10472,Q08379,Q10713,Q8TBA6 4 +Cytoplasmic side of membrane 0.2860577428149659 0.4935929788407228 0.6215936603579479 1.0 0.8979500524358693 47 Q9NR28,P15311,O15111,P36507,Q8TCT9,Q12959 6 +Ciliary plasm 0.3441979592964376 0.4919587220549997 0.6227485244633588 1.0 0.8979500524358693 20 P17252,Q15019,P04350,Q10713 4 +Carboxy terminal domain protein kinase complex 0.4344824062671211 0.4918677470078862 0.6228128402163491 1.0 0.8979500524358693 8 P18074,Q92759,P19447,Q9NYV4 4 +Supramolecular complex 0.2338626339540519 0.4861360130379153 0.6268707348825446 1.0 0.9009398161110022 370 Q05682,Q9UJW0,Q16181,P35580,P49257,Q9UQB8,Q16512,P67936,Q4VCS5,Q9Y2W6,Q13561,Q9Y5M8,O43663,P08670,Q13310,Q92974,Q96EY1,Q9BW19,P07197,Q969Z0,Q9NS87,O95900,P16949,P30622,P62753,P02545,Q01085,Q7Z739,P67809,Q9Y4Z0,Q8WUX9,Q9Y2A7,Q03001,P55735,Q13409,Q14157,Q5M775,O95235,Q15019,P12814,Q12959,Q9BZD4,P15311,Q14141,Q5VU43,Q07065,Q9Y3Y2,Q12849,Q13464,Q01082,A0MZ66,P06753,Q9H0B6,P14866,P17987,O00429,P51116,O15344,Q96EE3,P31483,Q96BK5,Q03252,Q96FJ2,Q14651,P04350,Q8NEZ5,O60313,Q8IWS0,Q7KZI7,P36507,Q9HCE1,Q08379,Q9NPI6,Q9BR76,P63000,P50570,P23258,O00139,P54646,Q00839,Q96JB5,P12270,Q9Y4I1,O75122,P20700,Q9BSJ2 86 +Rough endoplasmic reticulum membrane 0.3736010484272006 0.484588748696301 0.6279680964037375 1.0 0.9010843796015536 15 Q9UBF8,Q5BJF2,P49458,Q96A33,Q9Y5M8 5 +Zona pellucida receptor complex 0.4542737597130828 0.4585074319072671 0.6465879243610513 1.0 0.9130227248517284 5 P49368,P50990,P17987,P78371 4 +Transferase complex transferring phosphorus containing groups 0.2655469386791223 0.4553516867245928 0.6488562470778056 1.0 0.9130227248517284 85 P18074,P28340,O00411,Q00534,P24941,O15111,Q9NQG5,O95067,P54646,Q08AM6,Q8IUD2,P17858,P19447,P54619,Q9NR33,Q9Y2S7,Q9Y4A5,P25205 18 +Specific granule 0.2940431175704107 0.4539838710135848 0.6498404356980048 1.0 0.9130227248517284 37 O00264,Q9Y5K8,Q07065,P30519 4 +Tubular endosome 0.4570582074977405 0.4473428853731304 0.6546275071427194 1.0 0.9174934363674704 4 Q9Y5X3,Q9UNH7 2 +Rna polymerase ii transcription regulator complex 0.2845471262321639 0.444836613860478 0.6564378325298099 1.0 0.9184600543629394 43 P18074,Q15648,O75448,Q15233,Q9Y2X0,Q13503,Q15650,P17096 8 +Microtubule plus end 0.4134860058647498 0.4376196112065666 0.6616620524953822 1.0 0.9189820718980424 9 P30622,Q14980,Q99661,Q03001 4 +Terminal bouton 0.4317790218541728 0.4373396863461874 0.6618650179183925 1.0 0.9189820718980424 7 Q05682 1 +Nuclear inner membrane 0.3340484562929164 0.4322965376135112 0.665525903309492 1.0 0.9189820718980424 20 Q03252,P20700,Q5JTV8,Q9H1E5,Q5SNT2,O75844 6 +Nuclear replication fork 0.3364975528277076 0.4308254629784227 0.6665952835898787 1.0 0.9189820718980424 19 P28340,P15927,P35244,Q9UNS1,Q9Y2S7,P25205 6 +Apical part of cell 0.2687377083541451 0.4150610940540221 0.6780971796717343 1.0 0.9264101476785972 55 P35241,P36551,P15311,P26038,P51159,P53985,P08183,Q12959 8 +Contractile fiber 0.2705891691893095 0.41461209058354 0.67842589580395 1.0 0.9264101476785972 53 Q9UJW0,Q03001,P67936 3 +Gamma tubulin complex 0.4430006136916372 0.399496088074566 0.6895277056026416 1.0 0.9327228240626276 4 P23258 1 +Nlrp3 inflammasome complex 0.3630934607345453 0.3961958074936916 0.6919605839358318 1.0 0.9327228240626276 2 O00571 1 +Inflammasome complex 0.3630934607345453 0.3961958074936916 0.6919605839358318 1.0 0.9327228240626276 2 O00571 1 +Mediator complex 0.3480457226771991 0.387144545220581 0.6986492015598962 1.0 0.9384530136852096 16 Q15648,Q00534,Q9Y2X0,O75448,Q13503 5 +Lamin filament 0.3986933591670411 0.3835020152275741 0.7013475763297878 1.0 0.9394187198339826 3 P20700 1 +Axon hillock 0.3580173186025646 0.3765870523027873 0.7064805113407528 1.0 0.9405880821453624 2 Q9ULW0 1 +Cortical actin cytoskeleton 0.2866074394271691 0.3757921828903481 0.7070713997310345 1.0 0.9405880821453624 35 Q05682,P35241,Q01082,P46939,Q14254,P35240,P61160,O43707,O75955,Q14651,Q13813,P63167,P35579,P12814,Q9NS86 15 +Intermediate filament 0.3323662699638459 0.3715929052259857 0.7101959722574769 1.0 0.9405880821453624 18 Q03252,P20700,P30622,P08670,Q03001,P07197 6 +Ino80 complex 0.4232830743104036 0.3700641343505975 0.711334704676857 1.0 0.9405880821453624 6 Q96EZ8 1 +Postsynaptic specialization membrane 0.3890657337421698 0.3698371670850512 0.7115038203108841 1.0 0.9405880821453624 10 Q99996 1 +Centriole 0.3023136013103675 0.3687335959436205 0.7123263046563162 1.0 0.9405880821453624 26 Q9Y496,O75695,Q13464,Q96CW5,Q14203,P53350,Q8IXJ6,Q6UVJ0,Q9Y5Y2,P23258,O00139,Q9UIS9,P27695 13 +Mitochondrial small ribosomal subunit 0.3498795443964282 0.3669612176432306 0.7136479467767136 1.0 0.9405880821453624 15 P82933,Q9Y3D3 2 +Plasma membrane signaling receptor complex 0.3802733945132174 0.3650948341538439 0.7150406169038446 1.0 0.9405880821453624 11 O15111 1 +Microtubule end 0.38001000137265 0.3640163542867856 0.7158457970309837 1.0 0.9405880821453624 11 P30622,Q14980,Q99661,Q03001 4 +Ruffle membrane 0.2895674626604927 0.357900239179834 0.7204179717231436 1.0 0.9424860295770212 31 P51790,O75122,P35240,P15311,P50570,Q92974,Q9UNF0,Q06481,Q16512,P63000 10 +U12 type spliceosomal complex 0.3457792069954006 0.3477090561714708 0.7280586947392593 1.0 0.9483716755333677 15 Q9BWJ5 1 +Extrinsic component of mitochondrial inner membrane 0.426949507021228 0.3477018648086466 0.7280640960399969 1.0 0.9483716755333677 4 P49748,Q8NC60,Q8NI60 3 +Chromosomal region 0.2346768855573895 0.3400537964069079 0.7338160156057176 1.0 0.9513935712869738 172 Q16181,Q9UJW0,Q96BK5,Q9UQE7,Q8WUX9,P55735,Q9UBB9,Q15019,Q9BZD4,P15927,Q14141,Q00839,P51530,Q8IWS0,P27695,Q13561,P24941,P12270,O14757,P16104,Q9UBD5,Q14566,P83916,P05455,O75122,P33992,P54132,Q96EE3 28 +Transcription regulator complex 0.2591721956927711 0.3390212674614948 0.7345937088034378 1.0 0.9513935712869738 97 P18074,Q09472,Q12873,Q9Y2X0,P24941,Q15233,Q9BXJ9,P25490,P09429,Q6IAN0,Q13503,Q15650,Q8IUF8,P27695,Q92993,P17096 16 +Intermediate filament cytoskeleton 0.2833044168316413 0.3300581051662505 0.7413560581974026 1.0 0.9533227263306572 33 Q03252,P20700,P30622,P08670,Q03001,P02545,Q99471,P07197,Q9Y4J8 9 +Apical dendrite 0.381108717393238 0.3237346138757905 0.7461389627998314 1.0 0.9581102590497836 3 O15498 1 +Vesicle tethering complex 0.3051421314607309 0.3186049988983071 0.7500260622817956 1.0 0.9603733148764068 23 Q96AX1,Q9H267,P83436,Q6NUQ1,Q8IYI6,Q9UPT5,Q9Y2L5,Q8N1B4,Q9P253,Q7Z392 10 +Epsilon dna polymerase complex 0.3735550362539805 0.2995826602680054 0.7644955121192405 1.0 0.9720303222122744 3 Q9NR33 1 +Pigment granule 0.2555802977797579 0.2995687164994985 0.7645061494390786 1.0 0.9720303222122744 60 Q93050,P35613 2 +Trans golgi network 0.2544129105727442 0.2896776449321034 0.7720628601460935 1.0 0.9765828464714584 61 O14828,Q9P260,O60568,O75122,Q8IWJ2,P50570,P04062,Q12846,Q8NB49,O15127,P63000,Q4J6C6,Q01968 13 +Nbaf complex 0.3775052348190214 0.2798328620516482 0.7796057382256478 1.0 0.9787986243936088 8 P51532,Q92785,O14497,Q969G3,Q8TAQ2,Q92922,Q96GM5 7 +Contractile ring 0.3854766809753743 0.2765632573914459 0.7821154809177004 1.0 0.9787986243936088 7 O43663,P46939 2 +Spindle pole 0.2531395875914115 0.2761373405547524 0.7824425815948441 1.0 0.9787986243936088 57 Q9UJW0,Q9UQE7,Q08379,P23258,Q5SNT2,O00139 6 +Coated vesicle membrane 0.2542013533121374 0.2711848553322563 0.7862488603965683 1.0 0.9787986243936088 54 Q14108,P24390 2 +Cell substrate junction 0.2241050478656088 0.2646400847453956 0.7912867375417101 1.0 0.9787986243936088 188 Q9UJW0,P62841,Q03001,P50570,P35613,Q14108,P67936,Q14254,P15311,P61160,Q15366,Q9UNN8,Q10713,P17096,P36507,P08670,P62917,P62899,P46782,P35241,Q9BR76,P61513,Q9UNF0,P26038,P63000 25 +Dna polymerase complex 0.3537496532313554 0.2628420440955344 0.7926723280265957 1.0 0.9787986243936088 11 P28340,P09884,Q9NR33,Q9Y2S7,P25205 5 +Brush border 0.2747102762988697 0.253721556671646 0.7997106790750104 1.0 0.9787986243936088 30 Q9Y5X3,P15311,P47755,Q14344,Q14651,O00429,P40855,Q9UEY8,P35579,P12814 10 +Motile cilium 0.2772117840889316 0.2535942177314086 0.799809064220983 1.0 0.9787986243936088 29 P17252,Q16181,Q15019,Q14141 4 +Phagocytic vesicle 0.2634437993993426 0.2531578706695836 0.8001462206049523 1.0 0.9787986243936088 40 P08670,Q93050,P50570,Q06481,Q9Y487,Q01968 6 +Integrator complex 0.3361303841478079 0.2504463447846525 0.8022421933086037 1.0 0.97977540034912 13 Q96HW7,Q9NV88,Q9UL03,Q9NVM9,Q68E01 5 +Cytosolic large ribosomal subunit 0.2578515125353743 0.2493211686391473 0.803112358029533 1.0 0.97977540034912 47 P83731,P62899,P61513,P84098,P61254,Q02543,P46778,P62917,P51116,P46776,P27635,P18621,P50914,P62750,P62913 15 +Npbaf complex 0.3605625374027423 0.243577437491238 0.8075581043308289 1.0 0.9809161533470128 9 P51532,Q8WUB8,Q12824,O14497,Q969G3,Q8TAQ2,Q92922,Q96GM5 8 +Multivesicular body 0.3263728018653417 0.2418335239526973 0.8089091614005308 1.0 0.9809161533470128 14 Q96PU5,Q8WUX9 2 +Distal axon 0.2499345056844125 0.2408514176216036 0.8096702768835629 1.0 0.9809161533470128 55 Q05682,Q9Y4I1,P51790,O14795,Q96N67,Q5T1M5,Q14141,P50570,P51116,Q8IYI6,Q9UPT5,P27695,Q13561 13 +Protein phosphatase type 2a complex 0.3846383741781152 0.2376363114698289 0.812163184639793 1.0 0.9809161533470128 5 Q14738,P30153,P30154,Q15257 4 +Arp2 3 protein complex 0.3804601843125017 0.2372625348297584 0.8124531251972054 1.0 0.9809161533470128 6 P59998 1 +Side of membrane 0.2475312701315604 0.2350374231978109 0.8141796871700726 1.0 0.9809161533470128 72 Q9NR28,O96005,P15311,O15111,P36507,Q8TCT9,P51572,P00390,P08183,P63000,Q12959 11 +Synaptic membrane 0.2573960434722485 0.2341116980158502 0.8148982645615117 1.0 0.9809161533470128 45 Q99996,Q8NCG7,Q8IUD2,Q9UQB8 4 +Golgi cisterna membrane 0.3384696228444995 0.2322927589903119 0.8163106361306656 1.0 0.9813095944975024 12 Q10472,Q08379,Q10713 3 +9plus2 motile cilium 0.2924572825453469 0.2235540224473395 0.8231043429345788 1.0 0.9855448026660386 21 P17252,Q15019,Q14141 3 +Ciliary tip 0.3626493964443992 0.2097655872216116 0.833850632902186 1.0 0.9876161972950016 7 P63167,Q9Y496,Q96FJ2 3 +Scar complex 0.3718437064806634 0.2048371901329788 0.8376993295077182 1.0 0.9876161972950016 5 Q96F07 1 +Axon cytoplasm 0.2809635237495936 0.2045506924571581 0.8379231824353357 1.0 0.9876161972950016 24 Q03001,P27695 2 +Intrinsic component of endoplasmic reticulum membrane 0.2525025176396919 0.1976959391779696 0.8432829670779101 1.0 0.9913235399719514 45 Q9Y282,Q86UP2,Q15006,Q8TCT9,Q86XL3,Q9P0I2,P51572,Q15125,Q92643,Q96A33,Q96S52,Q8TB61,Q9UM00 13 +Nuclear ubiquitin ligase complex 0.3171377549046154 0.1820731640258795 0.8555253087050187 1.0 0.998747553950782 13 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4 +Cytoplasmic microtubule 0.2814273372022176 0.1818021916852242 0.8557379644711132 1.0 0.998747553950782 22 O75122,P29372,O15344,P23258,Q9BSJ2,Q9Y5M8 6 +Nuclear chromosome 0.245450403624596 0.1801892228468564 0.857004018879469 1.0 0.998747553950782 98 Q96BK5,Q9UQE7,P23258,Q9BRT9,Q92993,Q9Y4A5,P25205,P28340,P15927,Q00839,Q9UBU8,Q9NR33,Q9Y2S7,Q5PSV4,P25490,O14757,P16104,P35244,Q969G3,P33991,Q9UBD5,Q14566,Q92547,Q96EZ8,P33992,P54132,Q9UEY8,Q9UNS1 28 +Wash complex 0.364201773030024 0.1800406615075894 0.8571206464712662 1.0 0.998747553950782 4 P52907 1 +Nucleotide excision repair complex 0.3581841968972265 0.1798963055292424 0.8572339756465812 1.0 0.998747553950782 6 P28340,P19447 2 +Neuron to neuron synapse 0.2416147558961144 0.173090611672591 0.8625802043697814 1.0 0.998747553950782 66 Q9BY67,P50570,P62917,P51116,Q9UQB8,Q15366,Q99996,P50914,Q12959 9 +Inclusion body 0.2618004812842892 0.16428825432242 0.8695042277551221 1.0 0.9999631588066248 29 Q86U42,P28340,P12270,P07197,P27695 5 +Scf ubiquitin ligase complex 0.3376037064671912 0.1636449967859273 0.8700106198553268 1.0 0.9999631588066248 8 Q93034 1 +Basal dendrite 0.2830695730068577 0.1495965125334173 0.8810829598160774 1.0 1.0 2 O15498 1 +Lipid droplet 0.2605613445929746 0.1476987639712053 0.8825805071463775 1.0 1.0 28 Q8NBX0,Q07065 2 +Dendritic tree 0.2436162742591915 0.1460792572417149 0.883858821072802 1.0 1.0 111 Q9UQB8,Q16512,Q99996,Q14254,P21964,O60313,P54646,Q00839,Q12846,P27695,Q7KZI7,P12277,P51116,P17252,Q96EZ8,P51159,P50897,P62753,P63000 19 +Cell cortex region 0.2991467435625075 0.1443285607404219 0.8852410262029391 1.0 1.0 14 Q8IUD2,O75122 2 +Cell projection membrane 0.2356065204670502 0.1207427018819595 0.9038948351923568 1.0 1.0 67 P35240,Q9Y2A7,P50570,P40855,Q16512,Q15019,Q12959,P51790,P15311,Q12846,Q01082,Q92974,Q06481,Q9Y2J2,O75122,P46939,Q9UNF0,P26038,P63000 19 +Cluster of actin based cell projections 0.2488148640723923 0.1193613823627538 0.9049890549270958 1.0 1.0 34 Q9Y5X3,P15311,P47755,Q14344,Q14651,O00429,P40855,Q9UEY8,P35579,P12814 10 +Sex chromosome 0.3020081059858551 0.1185444097996073 0.9056363092102352 1.0 1.0 12 Q00839,P24941 2 +Hops complex 0.3275706769839374 0.1130151958434616 0.9100185078583832 1.0 1.0 5 Q96AX1,Q9H267 2 +H4 histone acetyltransferase complex 0.281690380588417 0.1120647030068159 0.9107721040092396 1.0 1.0 16 Q96EZ8,Q9UBU8 2 +Copi vesicle coat 0.2990384644221001 0.0859152052360157 0.9315338241745345 1.0 1.0 9 Q9Y3B3,P61923,P48444 3 +Aminoacyl trna synthetase multienzyme complex 0.2922155688622733 0.084688330631169 0.9325091734442864 1.0 1.0 11 Q15046,P54136,Q13155,O43324,P07814,P56192,Q9P2J5,P47897,Q12904,P41252 10 +M band 0.2688172043010683 0.0755294476914564 0.9397934685767212 1.0 1.0 3 P04075,Q01082 2 +Condensed nuclear chromosome 0.2517425078000574 0.0735026702441433 0.9414061192771376 1.0 1.0 24 Q92547,Q9UQE7,O14757,P16104,P54132,Q9UEY8,P23258 7 +Lamellipodium 0.2292965285570073 0.0719262544756615 0.9426605961069208 1.0 1.0 65 P35580,P35221,P35240,Q9Y2A7,P50570,Q9UQB8,Q16512,Q4VCS5,Q14254,P61160,Q12846,Q13576,Q13464,P19174,A0MZ66,O60749,P35241,Q9BR76,P63000 19 +Nuclear lamina 0.2974504904905203 0.0688818348215761 0.94508367788383 1.0 1.0 6 P20700 1 +Cation channel complex 0.2767759278769726 0.0685663352119467 0.945334816385887 1.0 1.0 13 Q99996 1 +Beta catenin destruction complex 0.290284005979083 0.0600958504598167 0.9520792948452504 1.0 1.0 6 P48729,Q9UJX6,P25054,P49841,Q9HB71 5 +Site of double strand break 0.237006067445343 0.0560403638155089 0.955309651992855 1.0 1.0 33 P61160,O94874,P15927,Q92747,P16104,P35244,P49959,P02545,Q9UNS1,P59998,P09874,Q68E01 12 +Extrinsic component of organelle membrane 0.2649009716006708 0.0518847314006309 0.9586205404654606 1.0 1.0 14 Q8NC60,Q9Y5X3,Q08AM6,Q15006 4 +H4 h2a histone acetyltransferase complex 0.2720154709164126 0.0507245439829016 0.9595450185511176 1.0 1.0 12 Q9UBU8 1 +Swi snf complex 0.2692422881102094 0.0456382731391992 0.9635985633863124 1.0 1.0 12 O96019,P51532,Q86U86,Q12824,Q92925,O14497,Q969G3,Q8TAQ2,Q68CP9,Q92922,Q96GM5 11 +Extrinsic component of endosome membrane 0.267403645055267 0.0453901152196493 0.963796359780562 1.0 1.0 4 P04083,Q9Y5X3,P40818 3 +Postsynaptic endosome 0.2272998805256761 0.0419501782297032 0.966538415135495 1.0 1.0 3 P20338,P20339 2 +Pericentric heterochromatin 0.2701310844529661 0.0408973185046354 0.9673777551839796 1.0 1.0 10 P83916,P42695 2 +Mismatch repair complex 0.2662881052002305 0.0404107788780606 0.9677656369678078 1.0 1.0 5 P52701,P54277,P43246,P20585 4 +Chaperonin containing t complex 0.2620400837571014 0.0317557908558674 0.9746668026253336 1.0 1.0 8 P49368,P50991,Q99832,P17987,P50990,P40227,P78371 7 +Spliceosomal snrnp complex 0.2261412555345793 0.0301894089954309 0.9759159950803548 1.0 1.0 41 O43290,P55769,Q9BWJ5 3 +Mitotic spindle midzone 0.2535581869635993 0.027445909840576 0.9781040812677136 1.0 1.0 6 Q00839 1 +Nuclear inclusion body 0.256615129351787 0.0265005810141787 0.9788580701806506 1.0 1.0 8 P12270 1 +Ctf18 rfc like complex 0.2316198445905499 0.0219030579296308 0.9825252854861652 1.0 1.0 5 P40937,P35250,P40938,Q8WVB6 4 +Calcium channel complex 0.2315285671552468 0.0080724136991909 0.9935592156921422 1.0 1.0 8 P17612,Q9BPX6,P0DP25,Q8IYU8,Q8NE86,Q15257,P17252 7 +Nurd complex 0.2375181454766279 0.00783607050085 0.9937477843152508 1.0 1.0 9 Q12873,Q8WXI9 2 +Histone deacetylase complex 0.225848321512289 0.007347743874053 0.9941374013591786 1.0 1.0 30 Q9Y4C1,Q5PSV4,Q12873,O75446,Q9UBU8,Q92993,Q9Y4A5 7 +Smn complex 0.1899556417097617 0.0059415117503203 0.9952593873984452 1.0 1.0 6 Q9NWZ8,P57678 2 +Flotillin complex 0.2056558312760253 0.0027115501829852 0.9978364986243464 1.0 1.0 7 P35221,Q14254 2 +Gemini of coiled bodies 0.1979665071770326 0.0010232586980429 0.9991835578256014 1.0 1.0 7 Q16637,Q14207,Q8TEQ6,Q9NWZ8,Q9UHI6,P57678 6 +Retromer complex 0.2320520637022252 0.0004250181404526 0.9996608845978814 1.0 1.0 10 Q9Y5X3,Q9UNH7,O60749,Q13596,Q96QK1 5 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2769914164a742165d8322d0e283be6a6e372edb --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Mutlalpha complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Nmda selective glutamate receptor complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor disc membrane", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Smad protein complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Super elongation complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC1", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG5", "ATG7", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C11orf54", "C12orf57", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CASP8", "CAST", "CBFB", "CBL", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC58", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPU", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG2", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM208A", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ITCH", "ITGB1", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGAT2", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NF2", "NFAT5", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPM3", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTULIN", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEF1", "PELP1", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R21", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAMM41", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLE3", "TLE4", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT112", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGGT1", "UHRF1", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR5", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["ABCB1", "ABHD10", "ABRAXAS2", "ACAD11", "ACADVL", "ACOX3", "ACSF3", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ADD3", "AGL", "AIMP1", "AIMP2", "AK6", "AKAP9", "ALDH3A2", "ALDOA", "ALG11", "ALG5", "ALG9", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANKFY1", "ANKLE2", "ANXA1", "APC", "APEX1", "APLP2", "ARCN1", "ARHGAP5", "ARHGEF2", "ARID1A", "ARID2", "ARPC1A", "ARPC4", "ASNA1", "ATAD3A", "ATAD3B", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP5A1", "ATP5B", "ATP5F1", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAIAP2", "BCAP31", "BLM", "BRMS1L", "BSG", "BTF3", "C21orf59", "CACYBP", "CADM1", "CALD1", "CALM3", "CALU", "CAMK2G", "CAPZA1", "CAPZA2", "CARS2", "CASP8", "CBX1", "CBX3", "CCDC124", "CCDC47", "CCDC58", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CDC23", "CDC5L", "CDK12", "CDK2", "CDK5RAP3", "CDK6", "CEP112", "CERS2", "CHCHD3", "CHD3", "CHEK1", "CHMP6", "CHMP7", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKB", "CLASP2", "CLCN3", "CLIP1", "CLPB", "CLPTM1", "COG7", "COL4A3BP", "COMT", "COPZ1", "COQ8A", "CORO1B", "COX6B1", "COX7A2", "CPOX", "CPT2", "CRABP2", "CRNKL1", "CRTAP", "CSNK1A1", "CSRP2", "CTNNA1", "CTNNBL1", "CUL3", "CUL5", "CYB5B", "CYFIP2", "CYP51A1", "DAGLB", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DCUN1D5", "DDRGK1", "DDX20", "DDX3X", "DHCR24", "DHFR", "DHRS7B", "DHX29", "DIABLO", "DLG1", "DLG3", "DNA2", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNM1L", "DNM2", "DOCK7", "DPF2", "DRG1", "DST", "DTNA", "DTX3L", "DYNC1I2", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECSIT", "EEA1", "EEF1D", "EEF1E1", "EHHADH", "EIF2B3", "EIF2B5", "ELOA", "EMC2", "EMC3", "EP300", "EPB41L3", "EPHX1", "EPRS", "ERC1", "ERCC2", "ERCC3", "ERGIC3", "ESPL1", "EXOC7", "EXOC8", "EXOG", "EZR", "FAF2", "FAM162A", "FAM98A", "FAM98B", "FASN", "FASTKD5", "FBXO22", "FDFT1", "FERMT2", "FKBP15", "FLOT1", "FLOT2", "FNTA", "FXR2", "GALNT1", "GATAD2B", "GATB", "GBA", "GCC2", "GCFC2", "GDE1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GGCX", "GINS4", "GLB1L2", "GLUD1", "GNA13", "GOLGA2", "GOLGA5", "GOLGB1", "GPSM1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GTF2B", "GTF2F1", "GTF2H4", "H2AFX", "HCCS", "HDAC6", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMMR", "HMOX1", "HMOX2", "HNRNPD", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPF1", "HSD17B12", "IARS", "ICMT", "IDH3A", "IDI1", "IFT27", "IKBIP", "ILVBL", "INTS13", "INTS3", "INTS4", "INTS6", "INTS9", "IQGAP2", "ITSN2", "KARS", "KAT5", "KAT7", "KDELR1", "KDM3A", "KDSR", "KIAA0391", "KIAA1468", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "KLC2", "KTN1", "LANCL2", "LARS", "LCLAT1", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LRPAP1", "LSG1", "LSM4", "MAN1A1", "MANF", "MAP2K2", "MAPK3", "MARK2", "MARS", "MBD1", "MBOAT7", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCRS1", "MCU", "MECP2", "MED1", "MED16", "MED21", "MED24", "MICU1", "MICU2", "MID1", "MORF4L1", "MOV10", "MPG", "MPV17L2", "MRE11", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL28", "MRPL46", "MRPS10", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTCH2", "MTFP1", "MTIF2", "MTOR", "MTX1", "MTX2", "MYH10", "MYH9", "MYO1D", "MYO5A", "NAA10", "NAA15", "NAA40", "NCAPD3", "NCBP1", "NCKAP1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "NF2", "NOA1", "NONO", "NPAT", "NPLOC4", "NPM3", "NSFL1C", "NSMCE3", "NSUN4", "NUBP2", "NUCB1", "NUCB2", "NUDT12", "NUF2", "NUMA1", "NUP93", "OCRL", "OPA1", "ORC3", "P3H1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAIP1", "PARP1", "PBRM1", "PCBP2", "PCID2", "PCYOX1", "PDCL3", "PDE4DIP", "PEX14", "PEX19", "PEX5", "PFDN4", "PFDN5", "PFKL", "PGRMC1", "PGRMC2", "PHB2", "PHF10", "PHF6", "PI4KB", "PIGK", "PIGS", "PIK3R4", "PINX1", "PKN1", "PLCG1", "PLD3", "PLK1", "PLOD3", "PLS1", "PMPCA", "PMS1", "PMVK", "POLA1", "POLD1", "POLDIP2", "POLE4", "POLRMT", "PON2", "POR", "PPP1CA", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP4R3A", "PPT1", "PRC1", "PRCP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKRA", "PROCR", "PRPSAP1", "PRPSAP2", "PSAP", "PSPC1", "PTCD3", "PTDSS1", "PTGES2", "PTPA", "QARS", "RAB27A", "RAB4A", "RAB5A", "RABGEF1", "RABL6", "RAC1", "RAD23A", "RAI14", "RARS", "RCN1", "RCN2", "RDX", "RETSAT", "RFC2", "RFC3", "RFC5", "RINT1", "RIOX2", "ROCK1", "RP2", "RPA2", "RPA3", "RPL10", "RPL11", "RPL14", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL31", "RPL37A", "RPL8", "RPN1", "RPN2", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS23", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "SAP30", "SART1", "SASS6", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCO2", "SCYL2", "SEC11A", "SEC13", "SEH1L", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SF1", "SF3B5", "SFPQ", "SFXN4", "SHMT2", "SHTN1", "SIRT2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC35B2", "SLFN11", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC3", "SMC6", "SMN1*", "SNRPD3", "SNU13", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SPECC1", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQOR", "SRP19", "SRP68", "SRP72", "SRP9", "SRPRB", "SSB", "SSBP1", "SSR1", "SSR4", "STAMBP", "STIP1", "STK4", "STMN1", "STOML2", "STX18", "STX4", "STX7", "SUPV3L1", "SYNCRIP", "SYNE2", "SYNGR2", "TARS2", "TBRG4", "TCP1", "TDRKH", "TFAM", "TFIP11", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8B", "TM9SF4", "TMCO1", "TMED7", "TMEM126A", "TMEM192", "TMEM199", "TMEM201", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX4", "TOMM22", "TOMM5", "TOPBP1", "TOR1AIP1", "TPM3", "TPM4", "TPR", "TPX2", "TRAPPC11", "TRAPPC8", "TRIP4", "TRRAP", "TRUB2", "TSG101", "TTC19", "TTLL12", "TUBB4A", "TUBG1", "TUBGCP2", "TUBGCP3", "TXNDC9", "TYMS", "U2AF1", "UBA5", "UBAP2L", "UBR4", "UFL1", "UFM1", "UFSP2", "UNC13B", "UQCC1", "UQCR10", "UQCRC2", "USO1", "USP8", "UTRN", "VAC14", "VBP1", "VDAC1", "VDAC2", "VIM", "VPS13C", "VPS18", "VPS33A", "VPS33B", "VPS35", "VPS52", "XAB2", "YBX1", "YIF1A", "YKT6", "YME1L1", "YTHDF3", "YY1", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_gomf/advanced/idx2term.json b/msigdb_gomf/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..288c09bc7949f453c554b12464efbb8d2de5b2ae --- /dev/null +++ b/msigdb_gomf/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "2": "Ion transmembrane transporter activity", "3": "Monooxygenase activity", "4": "Active transmembrane transporter activity", "5": "Tetrapyrrole binding", "6": "Proton transmembrane transporter activity", "7": "Primary active transmembrane transporter activity", "8": "Inorganic molecular entity transmembrane transporter activity", "9": "Dioxygenase activity"} \ No newline at end of file diff --git a/msigdb_gomf/advanced/plot_0.png b/msigdb_gomf/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..be084b9ed896b97de639e211f363b870756968fa --- /dev/null +++ b/msigdb_gomf/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6e8b4a7eacb12f0dbd6e3c6d22ec6460adb95763d5f0dd517d9f5b3d467646f +size 229427 diff --git a/msigdb_gomf/advanced/plot_1.png b/msigdb_gomf/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fcb86fa91644fd79d087560f3ca238881ddbb2c8 --- /dev/null +++ b/msigdb_gomf/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd224f9c676e8516af2f6ccb3d6aa8405934ef55fef1f5414ecd187eb319b9a9 +size 212680 diff --git a/msigdb_gomf/advanced/plot_2.png b/msigdb_gomf/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..8d19813405ec5f715813f3dc9bd16d0ca409e275 --- /dev/null +++ b/msigdb_gomf/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6666dfdb0201be6397fe3cbe937e518707de764c58ef9731d5beb1c2b090e731 +size 224781 diff --git a/msigdb_gomf/advanced/plot_3.png b/msigdb_gomf/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4828a0364aefcc94654ad331e05a4a72723b1bc9 --- /dev/null +++ b/msigdb_gomf/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:497345a3dc9b31ed5c33aeabbbfc30669fc9ca7afd61cc4497fcc6959bdcb3d6 +size 198249 diff --git a/msigdb_gomf/advanced/plot_4.png b/msigdb_gomf/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5ca77aa176e75ea4b5782971035332115c07d540 --- /dev/null +++ b/msigdb_gomf/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d8a2bc6344994e5c7abd4b16f5b467901a61818cca6d883527b3b52020df175 +size 223023 diff --git a/msigdb_gomf/advanced/plot_5.png b/msigdb_gomf/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..87816b47f542f81b050571d4a114f02bb6239f63 --- /dev/null +++ b/msigdb_gomf/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:525c68e3ef8b58f80c099f6e5bea6cd4bde50b9486c899337d3486b6ade0faca +size 201988 diff --git a/msigdb_gomf/advanced/plot_6.png b/msigdb_gomf/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4f721c151256d8ad4456fbc6e44aa5fbee53fe15 --- /dev/null +++ b/msigdb_gomf/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17f0aa90d467115d3d44ecf128649a1d428c1944e6111a2c3d86a6e6dce2290c +size 212023 diff --git a/msigdb_gomf/advanced/plot_7.png b/msigdb_gomf/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..9391e3e72646ee516beb4c317df4f80cde5de22a --- /dev/null +++ b/msigdb_gomf/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ea7207f205de71d1b0e9350725a84507331771c05205cedf8f6014850f25f3c +size 216433 diff --git a/msigdb_gomf/advanced/plot_8.png b/msigdb_gomf/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..f179a8fe6cb7e7898847c25b2df130c493eec1f1 --- /dev/null +++ b/msigdb_gomf/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c26b9858d00462d00b7faf3a6db31d263574565cf82fe50e0b5030afab77a672 +size 223580 diff --git a/msigdb_gomf/advanced/plot_9.png b/msigdb_gomf/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..2b776c6e7ad86b302f3e12afda38530e759646b7 --- /dev/null +++ b/msigdb_gomf/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c75a376b04bd1bf7f731acd7f63e69191f39a3fc06ea73f33635abafdd1434a +size 200317 diff --git a/msigdb_gomf/basic/idx2term.json b/msigdb_gomf/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..05090e8fc422ca31453baaf1d384aaefe979be90 --- /dev/null +++ b/msigdb_gomf/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "2": "Ion transmembrane transporter activity", "3": "Monooxygenase activity", "4": "Active transmembrane transporter activity", "5": "Tetrapyrrole binding", "6": "Proton transmembrane transporter activity", "7": "Primary active transmembrane transporter activity", "8": "Inorganic molecular entity transmembrane transporter activity", "9": "Dioxygenase activity", "10": "Steroid binding", "11": "Cation transmembrane transporter activity", "12": "Modified amino acid binding", "13": "Carboxylic acid binding", "14": "2 oxoglutarate dependent dioxygenase activity", "15": "Amide binding", "16": "Iron ion binding", "17": "Scaffold protein binding", "18": "Structural molecule activity", "19": "Transmembrane transporter binding", "20": "Four way junction dna binding", "21": "Tubulin binding", "22": "Metalloendopeptidase activity", "23": "Damaged dna binding", "24": "Cytoskeletal protein binding", "25": "Organic acid binding", "26": "Glycolipid binding", "27": "Oxidoreduction driven active transmembrane transporter activity", "28": "Single stranded dna helicase activity", "29": "Atpase coupled transmembrane transporter activity", "30": "Metallopeptidase activity", "31": "Glycosyltransferase activity", "32": "Anion transmembrane transporter activity", "33": "Kinesin binding", "34": "Microtubule binding", "35": "Atpase binding", "36": "Amyloid beta binding", "37": "Cytoskeletal motor activity", "38": "Dna helicase activity", "39": "Carboxylic ester hydrolase activity", "40": "Peptide n acetyltransferase activity", "41": "Molecular transducer activity", "42": "Structural constituent of cytoskeleton", "43": "Active ion transmembrane transporter activity", "44": "N acetyltransferase activity", "45": "N acyltransferase activity", "46": "Phospholipid binding", "47": "Microtubule motor activity", "48": "Protein homodimerization activity", "49": "Nadh dehydrogenase activity"} \ No newline at end of file diff --git a/msigdb_gomf/basic/plot_0.png b/msigdb_gomf/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7e30d912f5c3db75e9e9ac72640328abf90f84c3 --- /dev/null +++ b/msigdb_gomf/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8e2ca080021c8039e0f89a61d16567fb340b8db644d84ba1e7fbea81f571024 +size 137752 diff --git a/msigdb_gomf/basic/plot_1.png b/msigdb_gomf/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c7df621ba16621f95e6eb5d23f55f63198fa50fb --- /dev/null +++ b/msigdb_gomf/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3527db07f005f71470dc44864bed1d1ee809ae4dd0619b4343704e0c81d71230 +size 143819 diff --git a/msigdb_gomf/basic/plot_10.png b/msigdb_gomf/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..73f9e4d98020c9ded3a478f1f0c6269cf7e82efe --- /dev/null +++ b/msigdb_gomf/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1eeb8866566e957dad6431b8ca7942af18fd09e780432fbb4b7fa80075cff06a +size 133381 diff --git a/msigdb_gomf/basic/plot_11.png b/msigdb_gomf/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..872f874e8ac3c4940fc37094c675b6c12b37c925 --- /dev/null +++ b/msigdb_gomf/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c4510a306372b6c616edb27f760164d1ac092e84cf7e2d994063b72e5b3c536 +size 145851 diff --git a/msigdb_gomf/basic/plot_12.png b/msigdb_gomf/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..7d725fe2528c1eb0094e8fbed18430854637d7f5 --- /dev/null +++ b/msigdb_gomf/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c5237e195afdc731afa4ddc5f738866b84caf2a3c2c0912fb4ed1046ef90983 +size 132171 diff --git a/msigdb_gomf/basic/plot_13.png b/msigdb_gomf/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..7c02a37ff2423f7a469c775e74add34b9600fe5a --- /dev/null +++ b/msigdb_gomf/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56012ae2281bc0ce72c260178cba3cdd7ee98a3d9c47ebec8d345ebf16783884 +size 141309 diff --git a/msigdb_gomf/basic/plot_14.png b/msigdb_gomf/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..979d3214d37a136c760b0d828903fbb317675984 --- /dev/null +++ b/msigdb_gomf/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e22fbf3d85b7ff09f32f9588fdfdafc2db11602d1099e9524d95eceb21077e3f +size 146257 diff --git a/msigdb_gomf/basic/plot_15.png b/msigdb_gomf/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..8d16041f9c93d3918197dff4461599a5686cb9b0 --- /dev/null +++ b/msigdb_gomf/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5402eec69abf37be1d3999b612d998a2c3801e8cecc329469c5354a8054b3e6c +size 130802 diff --git a/msigdb_gomf/basic/plot_16.png b/msigdb_gomf/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..68ad65ffd155eff1ed3d6ba2b1f123c6217f85df --- /dev/null +++ b/msigdb_gomf/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e422ff8cb3a36ec39c6eb82dac5d5a60b033f71e29925e30b411c7a57e0a8abe +size 128796 diff --git a/msigdb_gomf/basic/plot_17.png b/msigdb_gomf/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..d77c38500469e595b26042120ce8728763cf659e --- /dev/null +++ b/msigdb_gomf/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a798f387f2b930685d2ea7d3daeda386a3bf3dea9b50e5a29d39ab618a7fde0b +size 126160 diff --git a/msigdb_gomf/basic/plot_18.png b/msigdb_gomf/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..41ce10b3fd69011c91212b6dc26acac540aed1a1 --- /dev/null +++ b/msigdb_gomf/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:feffb3d899814232649d980e77371f8b0b6a2274bbc6c6a2c8fc412e4a6ffacb +size 145313 diff --git a/msigdb_gomf/basic/plot_19.png b/msigdb_gomf/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..c1faa63ddfc294a8f280c8346d8e515ab127c821 --- /dev/null +++ b/msigdb_gomf/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:549f81bc042f0e0293e814ab48745eb4ccf14b2a80510bb1471fd4053f2ae358 +size 141512 diff --git a/msigdb_gomf/basic/plot_2.png b/msigdb_gomf/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ac9b8dc5024d6dbc73d48941da1064ea84377439 --- /dev/null +++ b/msigdb_gomf/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8eaa35398ecab796645d9b4790a0159af4bad3c5ef826b9ed964bcf80caf41e3 +size 142302 diff --git a/msigdb_gomf/basic/plot_20.png b/msigdb_gomf/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..32f1ec146c47fa83676bca66b350600e5686c9e9 --- /dev/null +++ b/msigdb_gomf/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e6fda8abe553507f6d83e479db9619f74a1c5eef1ad25f17ae6ed299beb41bf +size 136491 diff --git a/msigdb_gomf/basic/plot_21.png b/msigdb_gomf/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..4b0a4676eaff283252908ba1b91c331865b649fe --- /dev/null +++ b/msigdb_gomf/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eaf372c591e2f001ec5f84b993a61da1265f46f8c73d169aa8aa13233b3df8ce +size 136594 diff --git a/msigdb_gomf/basic/plot_22.png b/msigdb_gomf/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..a11822d08bbc4260db6aa5cc5ac5ac2c5530275a --- /dev/null +++ b/msigdb_gomf/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0e3fad7eadf42f90f9e07bb5de1441507cc3463de8f743590f9982679c6942f +size 138928 diff --git a/msigdb_gomf/basic/plot_23.png b/msigdb_gomf/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..4a01a9b568c1ebded7826ca3c91a35a2e5624fa4 --- /dev/null +++ b/msigdb_gomf/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:70e54c87912f7857c663f3aa5798ccc4c3d53ac6f27a534eb001878b2063ac82 +size 141289 diff --git a/msigdb_gomf/basic/plot_24.png b/msigdb_gomf/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..5d6ad26ad9bf5e2758f60ceeee1f283dbbfa361d --- /dev/null +++ b/msigdb_gomf/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a7f1bb2b9a74c6c0cf2c5d2802473c852f5dedee2f14e847bcdafa40ac3482b7 +size 142313 diff --git a/msigdb_gomf/basic/plot_25.png b/msigdb_gomf/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..42c8f3e164357e9d475bfdbb59fe67ef6e33dfda --- /dev/null +++ b/msigdb_gomf/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c27585ca962e103b34e77e8f6839c5b8a8ba1516699427c4f7a7e3ed51dd675 +size 134011 diff --git a/msigdb_gomf/basic/plot_26.png b/msigdb_gomf/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..1f54ae0ea30b8a20f643a92ea64d66e80a665bc1 --- /dev/null +++ b/msigdb_gomf/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31ad57cf962e528414189ae7e1df115ea4c2e7bdbc029f966273893393b930c4 +size 131985 diff --git a/msigdb_gomf/basic/plot_27.png b/msigdb_gomf/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..92e798c1da2f56396786afe43b0e733e92f03992 --- /dev/null +++ b/msigdb_gomf/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd164442047e0e758651feb38a70dc3ca158ee4c9ecd03a32ac9c1b9b46bc956 +size 146230 diff --git a/msigdb_gomf/basic/plot_28.png b/msigdb_gomf/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..39d83525f28e0ee0ef9bf97057eb5a8fc98da4bd --- /dev/null +++ b/msigdb_gomf/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6368c6df0a793077d425e6fb885afda6db608d4f139d2622ca888f104bb1849c +size 139973 diff --git a/msigdb_gomf/basic/plot_29.png b/msigdb_gomf/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..0e6fc56089c45af28859af2ac49162d6f8cdfcf9 --- /dev/null +++ b/msigdb_gomf/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0128e7af4e782723b9c08192e9592900fe4e2dab028924e1dbfa9f1c6f71212 +size 142189 diff --git a/msigdb_gomf/basic/plot_3.png b/msigdb_gomf/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d7f0ab85fc47f3d84c909b825cae88d455b61fad --- /dev/null +++ b/msigdb_gomf/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:decb7d4c08f4da1b725f40b233f94cbdf0fc65e90e9c272147f712c5c54a3107 +size 140132 diff --git a/msigdb_gomf/basic/plot_30.png b/msigdb_gomf/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..b835c821fb49496af8e6385bc7c7074177dc196a --- /dev/null +++ b/msigdb_gomf/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c54562dc3c9c071a423cb0d69aa74aff5bd89485e9007c38eda7630b90b8475f +size 143267 diff --git a/msigdb_gomf/basic/plot_31.png b/msigdb_gomf/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..d51958cf7bd2ea4cd6a2e03d9ddfb86ea9352c3b --- /dev/null +++ b/msigdb_gomf/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79e007e60806d1c4f967ac7f01b3e8b90a02b93783b8d8f2707615b782101577 +size 141797 diff --git a/msigdb_gomf/basic/plot_32.png b/msigdb_gomf/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..0d02d64397e9d74e2d8630fa86ad764fcfd79a8c --- /dev/null +++ b/msigdb_gomf/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4bfe5a51a8ed82ea17c665790443e8aaa7e5fb7907c06bb1ab87b5de8019157 +size 141075 diff --git a/msigdb_gomf/basic/plot_33.png b/msigdb_gomf/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..479e98bf959e8e4202ea84d40705eed680c9ab9d --- /dev/null +++ b/msigdb_gomf/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f6d32b563b4af238b026f01da422168233e6780336c3d816a378eef5a5e8968 +size 132929 diff --git a/msigdb_gomf/basic/plot_34.png b/msigdb_gomf/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..cabf2ff82f023ee874cdf7cedb5726eef8a25019 --- /dev/null +++ b/msigdb_gomf/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e18a7fce81c036290b0702d65dad9a571b253614b94fec3a3e558337b5204939 +size 143658 diff --git a/msigdb_gomf/basic/plot_35.png b/msigdb_gomf/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..8b495973e6a5201466f16e91b10b558099ed49e9 --- /dev/null +++ b/msigdb_gomf/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74f799de4acd18bc74918e1155645b7fab6617822d3fc31096f1021ab4db1d5d +size 133370 diff --git a/msigdb_gomf/basic/plot_36.png b/msigdb_gomf/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..bac155a77da6d586d336912a849b281698e4f437 --- /dev/null +++ b/msigdb_gomf/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cbcf4585a45a9cf6e445afebba3a705d11abc5988284a5233e4b2f0b3c92c7e3 +size 134530 diff --git a/msigdb_gomf/basic/plot_37.png b/msigdb_gomf/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..fef063e66236ca25458f3fcf5d8c48cb07b6ebb3 --- /dev/null +++ b/msigdb_gomf/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:faee2442db30b8d4d35309838815331d1e16dcf6f1cf384602d0a4badd3b607c +size 147758 diff --git a/msigdb_gomf/basic/plot_38.png b/msigdb_gomf/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..aef66fdb4ab8adde2fa6773ac7d3df37b94e8242 --- /dev/null +++ b/msigdb_gomf/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:190a1a64aeb1bdfb0777c7e7cf70206a072512357bbc691e599a81d26b3f1676 +size 144586 diff --git a/msigdb_gomf/basic/plot_39.png b/msigdb_gomf/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..57f5145237ddb80c290cf6d57e8adfad940bd86e --- /dev/null +++ b/msigdb_gomf/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:583bfe04b1351b62b3654fc71fa42e44d1f897d7613d8c8a24a1389a92b5bc48 +size 144770 diff --git a/msigdb_gomf/basic/plot_4.png b/msigdb_gomf/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..78043575f1eebdb1a66f433e6345d41c5ac0271a --- /dev/null +++ b/msigdb_gomf/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6bbf47746065e74c92412d611dae5dc2ed7141e46e03b8ef56723df52a2bc119 +size 150118 diff --git a/msigdb_gomf/basic/plot_40.png b/msigdb_gomf/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..d5d57baae5495c280d5dd0957d015258a0f9f7d6 --- /dev/null +++ b/msigdb_gomf/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5974f62adf2c2d6b8e1b83235409f2860b231cb2e41b9ca75bbb85834240dc2a +size 142901 diff --git a/msigdb_gomf/basic/plot_41.png b/msigdb_gomf/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..f5e4a22c5a73f6ae63195249adb6e6b3ef6a15ce --- /dev/null +++ b/msigdb_gomf/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6024637d71c025e8ba1ebf5c34c4f5878034819cf4d5e625aef80e923398978 +size 147671 diff --git a/msigdb_gomf/basic/plot_42.png b/msigdb_gomf/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..d5b4ec44b38a5e2eafe5c1a566f8656af8b0161f --- /dev/null +++ b/msigdb_gomf/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72a7ad2ae6b4f9fcf0bb4f942892ffdd6f8fd64c14517d66c0ccac1abd7a4ba6 +size 151679 diff --git a/msigdb_gomf/basic/plot_43.png b/msigdb_gomf/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..1e72e74b663cdc6b979cd0e2b815650ec658f9d6 --- /dev/null +++ b/msigdb_gomf/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d63654659bbd07077dac242887ee143f961e13513cbbe1bfa5ec29670bd65f64 +size 149335 diff --git a/msigdb_gomf/basic/plot_44.png b/msigdb_gomf/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..3e763ea9bdb64ef89bbe23b0a5a71fe1fb3078dc --- /dev/null +++ b/msigdb_gomf/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:830e5ccb879acf73a68b5a2c1b717a18c325fcf27be8d07fc115c5473cb1c84b +size 137684 diff --git a/msigdb_gomf/basic/plot_45.png b/msigdb_gomf/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..86ed539a0c5707d6910b49d1970e538748208eb7 --- /dev/null +++ b/msigdb_gomf/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91b63cab8bce6d833d54fa36197655fe1c6df8d84f4e1cfe2aebc4826182fdc8 +size 131259 diff --git a/msigdb_gomf/basic/plot_46.png b/msigdb_gomf/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..04a90865e20eed5edf30e915ff5ec58f19464032 --- /dev/null +++ b/msigdb_gomf/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f97258e8ef8b75e84f1633b6236709c7a2bc30483d477b5ea1b9286fdd9ff2e +size 135537 diff --git a/msigdb_gomf/basic/plot_47.png b/msigdb_gomf/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..5cd497e392021909cca54bc5abec052fc4217ea8 --- /dev/null +++ b/msigdb_gomf/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:423f6b67475c456b22e3d5260d22790fb61dab3ba7ccae62f751aeb676562110 +size 143439 diff --git a/msigdb_gomf/basic/plot_48.png b/msigdb_gomf/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..3305d409172b046f437549f8554e19c650922d51 --- /dev/null +++ b/msigdb_gomf/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e88636878003bbb4e53f782544cc19472141a491aa82c22903d1206c5cc5685 +size 145695 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..8170d17bc3b9fbbc6fb761d897206815196f28d1 --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ef86c840736d420dbba2eeaee16abb7a212dd8f281177eca1c3ca760d508c13 +size 146260 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..55e63a79db706da042c256c1b033cee832798071 --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9422c6889990a5b2850e238bd6285bd51f88d3a31b61106264fc3bd5049df092 +size 133725 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..1659d1dbb3369a052db31e2fc498d1e3ec0efb63 --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f876881b01f831b2e5385ff582d253ee2cc6726bc2c6eadafbe9e5a4605e574f +size 147328 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..8a8d997fdbc1af5fb70f651a1bb2d33d9ed99eec --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4cc26e1f5442767669c16d397735e87a18670501766d9f2611259287376a617 +size 147038 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..c0566f228105eb15b647d2bde6845fb6d466da6e --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1df6d5c43d2ebb87d161b9b7da4272c1796d94d35afcfa084fdcdc907ac9c3d5 +size 144490 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..8d165d2d209952fb1d7d602e3269e3bec2d04156 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41e1f6185afd20f1882d5987f39051dfe61d5687d0248c65f6397ad2d2e87917 +size 137569 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5a7f82628e1f5784d7c639ec3a1ea7a7d5049ff8 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2be7db4b9ec53d4d5b11b7c1d01fa6373eb5e1f85d304dddc1a8a163c915ef1 +size 217932 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0fc4beb923b8c007b7d2da8835a4760916545337 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,28 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Transporter activity 31 156 4.307647377518062 1.650001540842716e-05 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 4.7558454848111016e-08 1.545461705173894e-06 2.834673605637742e-06 0.0004240202430715 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 12 31 3.2602370762821176 0.0011131912309723 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.008915334119445 0.0117928333352128 0.0072747996350223 0.005404303083764 +Ion transmembrane transporter activity 17 90 2.70796697261216 0.0067696758930071 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 0.0028276531829997 0.028114793198251 0.0005353993731194 0.0293481411526038 +Protein transporter activity 4 13 2.672326130636066 0.007532739948187 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0001966513360574 0.0016492758756177 0.0002861885476851 0.0063685282240186 +Organic acid transmembrane transporter activity 4 18 2.613043100321354 0.0089739984356207 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0390792451218721 0.0268041613697724 0.0242455864981032 0.2364098572110782 +Macromolecule transmembrane transporter activity 2 11 2.590730439941883 0.0095772476933695 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 9.905963195641525e-05 0.0008461128461095 0.01180448121602 0.0708751155690715 +Monooxygenase activity 5 8 2.558683299769785 0.01050694123001 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0067836126853756 0.0020687914080252 0.0004179970223822 0.0016034677277021 +Protein transmembrane transporter activity 2 10 2.5068503203565013 0.0121812282410611 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 5.966461606118925e-05 0.0005152543640852 0.0074273483269255 0.0470360579614364 +Cytokine activity 2 5 2.4358134827556337 0.0148583437575051 1.4368932038834952 5.75 0.9689346120623524 0.3423153019744804 1.105326054892273 0.6058973927039436 0.8855586242183912 0.2854448354224685 0.1050728360238821 0.0215793786244467 0.0195244436529747 0.1093101132411038 +Phosphatidylcholine binding 3 9 2.3547393611463128 0.018535701660062 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 4.92948696733527e-05 1.2834146389040458e-05 0.0004862334359502 0.0063533232968262 +Active transmembrane transporter activity 13 66 2.349269873317255 0.0188102676670973 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.0658179143752829 0.1262451155174056 0.0037181381061378 0.0379852043762504 +Tetrapyrrole binding 6 16 2.3450172061305974 0.0190262015548337 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0019313424584052 0.0016915485936643 0.0003015006992345 0.0043344107943581 +Proton transmembrane transporter activity 7 35 2.29953061830703 0.0214748267876812 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 0.045540604112063 0.1563084442837106 0.000401529451794 0.0029972169690089 +Ceramide binding 2 5 2.259099434136333 0.023877200344319 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 2.5421325666390244e-05 0.0002227826640135 0.003355333516566 0.0028040242445346 +Palmitoyl protein hydrolase activity 1 5 2.235815437974719 0.0253638632609995 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0539630923046902 0.1084298440104649 0.0328731354880699 0.113339965404402 +Peptide alpha n acetyltransferase activity 2 5 2.2185012780496343 0.0265206725431152 1.5946601941747574 4.652912621359223 0.3684306572835352 0.4706661875391733 1.308401021876154 0.7685671084114669 0.9855042784289884 0.3024126131037989 1.0 1.0 0.0231366382468947 0.010684483318579 +Primary active transmembrane transporter activity 12 46 2.1991365578964426 0.0278682137547716 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.0177010820449216 0.1061761164696546 0.0086623262039441 0.0139171910255589 +Quaternary ammonium group binding 3 13 2.195021587526772 0.0281620492392791 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.000132954444525 4.937215337333033e-05 0.0017432511761074 0.0035606647558243 +Inorganic molecular entity transmembrane transporter activity 17 68 2.1768743970679494 0.0294899401896595 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.025209912091816 0.081769486250894 0.00622666829251 0.0852043023884082 +Dioxygenase activity 7 20 2.1564843342452136 0.0310458657342742 4.966019417475728 18.946601941747577 0.431149201997438 0.5860948271154753 2.499283524441613 3.0888246903576806 0.809438844885216 0.3223440754880037 0.2703718142220204 0.1365892396200844 0.2274506769816413 0.1130329164300312 +Sphingolipid binding 2 7 2.129906729306414 0.0331793144730172 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 7.136619417616994e-05 0.0006140521777265 0.0087554356838108 0.0098879726868235 +Steroid binding 5 21 2.095060744355619 0.0361655929785689 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 7.213643531833928e-05 9.61855521325839e-05 0.000162079776431 0.0091015487948519 +Single stranded dna endodeoxyribonuclease activity 0 5 2.0633317726470164 0.0390811173312199 1.866504854368932 3.546116504854369 -0.2402247695705045 0.5899209201137131 1.1122200389423753 0.8067130154765326 0.8375394742847202 0.2941320120564206 0.0451714964804377 0.0912026913027489 0.2175647207167039 0.3934410105686676 +L ascorbic acid binding 1 7 2.060680901798879 0.0393334928214383 2.3300970873786406 7.104368932038835 0.5677763323556714 0.4604224594801547 1.449059618159932 1.3886783336592343 0.918266587379424 0.3051881949297183 0.0755969254036216 0.1500965904253892 0.3411306657380243 0.1998160014011807 +Cation transmembrane transporter activity 15 64 2.059916716666277 0.0394065033176562 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0900582149989606 0.3774755110418319 0.0249729089717072 0.1576614391805358 +Modified amino acid binding 6 22 2.039150513547854 0.041435008075694 4.446601941747573 21.354368932038835 0.8157790161756342 0.4133026066112408 2.099367243274066 1.7995833767593454 0.9656025978141096 0.3166170247143811 6.647148274845446e-05 0.0010870000966342 0.0001418153943193 0.0081332818022798 +Pyrimidine nucleotide binding 0 5 1.9950522786215623 0.0460371783516206 1.172330097087379 5.012135922330097 0.2915756451416036 0.3812019786090051 1.420006634664861 0.3375357600197503 1.227384965028187 0.3091745000997537 0.0273477531405618 0.0557540441617295 0.1368589802283267 0.2591162943571684 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cfba4619cbd892d7bb4a0591ef7fff5068c04ae6 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 1370, + "title": "Average number of proteins per term", + "value": 17.736496350364963 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e11b6cdf9b20df0f914b535cb3bc2571941f9a8b --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8dd34a46e2de0aafe69cceb0498088d9da1ec13 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,443 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.4795870399056647 4.307647377518062 1.650001540842716e-05 0.0223516242598526 0.0103351211196207 156 O60830,Q99595,Q70HW3,Q9H2D1,Q9Y5J9,Q93050,O43676,O75964,P04062,P21796,Q9NS69,P08183,Q8WTV0,Q9Y487,P45880,Q9P0J0,Q9Y5K8,Q9HD20,Q00169,O15173,Q9UBX3,Q9UDW1,Q9BSK2,Q6P4A7,P18859,P53007,P14854,P12235,Q8NB49,P38435,P53985 31 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9868617497760512 3.3849517614343614 0.0007119076424908 0.62305681342265 0.0188426430025952 2 P30519 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6546396941801109 3.2602370762821176 0.0011131912309723 0.7825793810232644 0.0206090808977306 31 P30519,O60568,Q32P28,Q9BU89,P09601,Q8IUF8,Q16850,Q9NWT6,Q6NYC1,Q14534,Q9Y4C1,Q15800 12 +Glycerophospholipid flippase activity 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.9120098767600407 0.02515382179802 2 P08183 1 +Floppase activity 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.9120098767600407 0.02515382179802 2 P08183 1 +Atpase coupled intramembrane lipid transporter activity 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.9120098767600407 0.02515382179802 2 P08183 1 +Flippase activity 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.9120098767600407 0.02515382179802 2 P08183 1 +Phosphatidylethanolamine flippase activity 0.9271424305762828 3.1259134345281376 0.0017725372019907 0.9120098767600407 0.02515382179802 2 P08183 1 +Vitamin d binding 0.9262466407882856 3.1219658129559127 0.0017964779870238 0.9148540313153068 0.02515382179802 2 P04062 1 +Rage receptor binding 0.9116154075843462 3.0572223781584387 0.0022339847406636 0.9532986784430872 0.0291481818543728 2 P09429 1 +Phospholipase d activity 0.900865930128385 3.009334372045245 0.0026182079053513 0.9724471341802892 0.0323148182912739 2 P09601 1 +Stat family protein binding 0.8853389071364461 2.939676740340589 0.0032855482845439 0.988986261635795 0.0369361643726814 2 Q8TDB6 1 +H3 histone acetyltransferase activity 0.8727978501045099 2.8829912182146593 0.003939184224986 0.9955164478126676 0.042161581158054 2 Q09472 1 +Lipase activator activity 0.8707076739325068 2.8735065581789017 0.00405942649917 0.9961999194770216 0.0426063848834583 2 Q9Y263 1 +Cardiolipin binding 0.8575694237085728 2.8136446163751394 0.0048983347818496 0.9988021274780364 0.0462808182836828 2 O60313 1 +Four way junction helicase activity 0.8530904747685781 2.7931404690194945 0.0052199019281142 0.999230673653403 0.0478292374954783 2 P46063 1 +Peroxisome proliferator activated receptor binding 0.8456255598685992 2.7588571097541186 0.0058003891268973 0.9996542066115718 0.051267955508706 2 P17096 1 +Lipase binding 0.8405494177366404 2.7354657938174296 0.0062292060146167 0.9998085154057326 0.0534852671670535 2 P30533 1 +Phosphatidylcholine transporter activity 0.9238033227282706 2.7234861688807723 0.0064596920353516 0.9998606448993852 0.0549675657666571 3 P08183 1 +Ion transmembrane transporter activity 0.435635401754948 2.70796697261216 0.0067696758930071 0.9999091218450604 0.056208824081332 90 P18859,P45880,P53007,Q70HW3,Q9H2D1,Q9Y5K8,Q93050,Q9UBX3,P14854,Q9HD20,O75964,Q9UDW1,P21796,Q6P4A7,P12235,P53985,Q9Y487 17 +Protein transporter activity 0.7956205684082617 2.672326130636066 0.007532739948187 0.99996829126668 0.0614277007679538 13 O60830,Q9Y5J9,Q99595,Q9NS69 4 +Signaling receptor inhibitor activity 0.8172588832487347 2.627320087129944 0.0086060337853153 0.9999927990166873 0.0654933673145453 2 P30533 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8984468339307028 2.61628405502149 0.0088892572602479 0.9999951315420548 0.0665629565623683 3 Q16850,Q15800 2 +Organic acid transmembrane transporter activity 0.6963502123876592 2.613043100321354 0.0089739984356207 0.9999956697054416 0.0668172709608718 18 Q9H2D1,P08183,P53007,Q9UBX3 4 +Macromolecule transmembrane transporter activity 0.8234112514087344 2.590730439941883 0.0095772476933695 0.999998119671615 0.0677927168135914 11 O60830,Q99595 2 +Monooxygenase activity 0.8801587744846714 2.558683299769785 0.01050694123001 0.9999994806379082 0.0711735742339802 8 P30519,Q9BU89,P09601,Q16850,Q15800 5 +Porin activity 0.9657849396634366 2.550675661934154 0.0107514328128119 0.9999996297978124 0.0718510387978167 4 P21796 1 +Wide pore channel activity 0.9657849396634366 2.550675661934154 0.0107514328128119 0.9999996297978124 0.0718510387978167 4 P21796 1 +Structural constituent of eye lens 0.8804942076185589 2.539579404002321 0.0110985848656994 0.9999997711200378 0.0734544022512477 3 P36551 1 +Voltage gated chloride channel activity 0.7942669453568205 2.519230206129232 0.0117611734207283 0.9999999086264604 0.0767650798996657 2 P51790 1 +Protein transmembrane transporter activity 0.8271411436077203 2.5068503203565013 0.0121812282410611 0.999999948965176 0.0787183145766688 10 O60830,Q99595 2 +Scavenger receptor activity 0.8709634181506375 2.498585803860616 0.0124689952874761 0.9999999657616052 0.0799693137507768 3 Q14108 1 +Rna polymerase iii transcription regulatory region sequence specific dna binding 0.7835174679008674 2.4682390835253343 0.0135779597653118 0.9999999926550076 0.0837919138670145 2 P42345 1 +Phosphatidylglycerol binding 0.8578255675029818 2.441767671262537 0.0146155490118431 0.999999998262936 0.0875731616230905 3 O60313,Q00169 2 +G quadruplex rna binding 0.7778441325768692 2.441209956511163 0.0146381416143706 0.9999999983166514 0.0875731616230905 2 Q96EZ8 1 +Cytokine activity 0.9204366106458286 2.4358134827556337 0.0148583437575051 0.9999999987606436 0.0885040475990525 5 P43490,P14174 2 +Deoxynucleoside kinase activity 0.770976410868893 2.408382255670974 0.0160233939999694 0.9999999997550152 0.0938121785468296 2 P55263 1 +Lysophosphatidic acid binding 0.7691848312928968 2.3997990270085103 0.0164040754118173 0.9999999998558192 0.094318196155473 2 P50897 1 +Phosphatidylcholine binding 0.8146415812675182 2.3547393611463128 0.018535701660062 0.9999999999926196 0.105807963642854 9 Q14108,P45880,P21796 3 +Active transmembrane transporter activity 0.4294095554406875 2.349269873317255 0.0188102676670973 0.9999999999949696 0.1068274431562383 66 Q9P0J0,P53007,P51970,Q9Y5K8,Q9HD20,Q9UBX3,O43676,Q9UDW1,P12235,P14854,P16615,P53985,P08183 13 +Tetrapyrrole binding 0.6814523909182827 2.3450172061305974 0.0190262015548337 0.9999999999962792 0.1068274431562383 16 O15173,P30519,O00264,Q9H7Z7,P09601,O43169 6 +Peroxisome targeting sequence binding 0.8276028462486698 2.30969960549053 0.0209047906767003 0.9999999999997308 0.1150183262131707 3 P50542 1 +Type i transforming growth factor beta receptor binding 0.7485816661689815 2.3005141466796335 0.0214191087558222 0.9999999999998688 0.1167480662663621 2 Q9UNH7 1 +Proton transmembrane transporter activity 0.5085292377516953 2.29953061830703 0.0214748267876812 0.9999999999998788 0.1167480662663621 35 P18859,Q9Y5K8,Q93050,P14854,Q9UDW1,O75964,Q9Y487 7 +Intramembrane lipid transporter activity 0.823063502396112 2.289700134766524 0.0220387056023469 0.9999999999999448 0.1188701837606905 3 P08183 1 +Tropomyosin binding 0.7444013138250272 2.280240152449961 0.0225934491335499 0.9999999999999748 0.1213844129920136 2 Q05682 1 +Protein carboxyl o methyltransferase activity 0.818900811905312 2.2713228440687168 0.0231274413212845 0.999999999999988 0.1237679476959367 3 O60725 1 +Ceramide binding 0.8773668581240164 2.259099434136333 0.023877200344319 0.9999999999999958 0.1268325970171432 5 P45880,P21796 2 +Solute proton antiporter activity 0.7381307853090481 2.24974790735415 0.0244649525148208 0.9999999999999982 0.1279274234553608 2 P51790 1 +Peptide hormone binding 0.7363392057330493 2.241017983057971 0.0250249101747239 0.9999999999999992 0.1293740639221578 2 P42892 1 +Palmitoyl protein hydrolase activity 0.8717522791750931 2.235815437974719 0.0253638632609995 0.9999999999999994 0.1297642838295375 5 Q9NUJ1 1 +Peptide alpha n acetyltransferase activity 0.8675860539597957 2.2185012780496343 0.0265206725431152 1.0 0.1345678569780294 5 Q9BXJ9,P41227 2 +Primary active transmembrane transporter activity 0.4573953670033346 2.1991365578964426 0.0278682137547716 1.0 0.138834373978317 46 Q9P0J0,P51970,O75380,P06576,Q9Y5K8,Q9HD20,P14854,O43676,Q9UDW1,P16615,P08183,O75306 12 +Quaternary ammonium group binding 0.7031196748675399 2.195021587526772 0.0281620492392791 1.0 0.1397898820935231 13 Q14108,P45880,P21796 3 +Inorganic molecular entity transmembrane transporter activity 0.4122695276720407 2.1768743970679494 0.0294899401896595 1.0 0.1441666236037639 68 P18859,P45880,O43681,P06576,Q9Y5K8,Q93034,Q93050,Q9HD20,Q9UBX3,Q9UDW1,O75964,P56134,P21796,P14854,P12235,P16615,Q9Y487 17 +Immunoglobulin binding 0.7211107793371121 2.16649549079751 0.030273344059839 1.0 0.1465529376748392 2 P17931 1 +Dioxygenase activity 0.5967079946527261 2.1564843342452136 0.0310458657342742 1.0 0.1492380212489674 20 O60568,Q32P28,Q8IUF8,Q9NWT6,Q6NYC1,O00625,Q9Y4C1 7 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.7184234099731319 2.1532857804755214 0.0312962256223396 1.0 0.1497244611784624 2 Q8IXB1 1 +Phospholipase c activity 0.7175276201851304 2.14887866115268 0.0316440197656762 1.0 0.1500079829722367 2 P19174 1 +Sphingolipid transfer activity 0.7160346372051324 2.1415291582217932 0.0322313896854034 1.0 0.1517422813367789 2 Q9Y5P4 1 +Sphingolipid transporter activity 0.7886207558364791 2.1365802324769287 0.0326321488308689 1.0 0.1527460180778719 3 P08183 1 +Sphingolipid binding 0.8080752228223491 2.129906729306414 0.0331793144730172 1.0 0.1538240175872632 7 P45880,P21796 2 +Phosphotransferase activity nitrogenous group as acceptor 0.7862380783496337 2.1258991560541824 0.0335116571860334 1.0 0.1538240175872632 3 P12277 1 +Glutathione disulfide oxidoreductase activity 0.7842477933488387 2.116968440776521 0.0342625263107958 1.0 0.1559158345630207 3 P00390 1 +Steroid binding 0.5789780046736452 2.095060744355619 0.0361655929785689 1.0 0.1624487291168505 21 O15173,P45880,P04062,P21796,Q14108 5 +Folic acid binding 0.7750442695026866 2.075568989786396 0.0379338319860549 1.0 0.1687316552626469 3 P00374 1 +Aspartic type endopeptidase inhibitor activity 0.7005076142131996 2.0647782714526373 0.0389439846870165 1.0 0.1716061882813185 2 Q13464 1 +L ascorbic acid binding 0.792498225861783 2.060680901798879 0.0393334928214383 1.0 0.171932832946462 7 Q32P28 1 +Cation transmembrane transporter activity 0.4064961057412345 2.059916716666277 0.0394065033176562 1.0 0.171932832946462 64 P18859,Q70HW3,P06576,Q9Y5K8,Q93034,Q93050,Q9HD20,Q9UDW1,P14854,O75964,P56134,P12235,P16615,Q9HC21,Q9Y487 15 +Sulfatide binding 0.7694145758661808 2.0501635880896787 0.0403484699016978 1.0 0.1733795724849845 3 P55145,P50897 2 +Acetylgalactosaminyltransferase activity 0.696625858465199 2.0455015097160003 0.0408054405198845 1.0 0.1733795724849845 2 Q10472 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.696625858465199 2.0455015097160003 0.0408054405198845 1.0 0.1733795724849845 2 Q10472 1 +Phospholipid transfer activity 0.7682221641605662 2.0447746336193413 0.0408770816880657 1.0 0.1733795724849845 3 Q00169 1 +Chemoattractant activity 0.839756022125973 2.041709650813951 0.0411803408932782 1.0 0.1739273907150303 4 P14174,P09429 2 +Modified amino acid binding 0.5621673123703363 2.039150513547854 0.041435008075694 1.0 0.1741287149193275 22 Q9H7Z7,P09429,Q06481,Q14108,Q8WTV0,P00374 6 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.6939384891012154 2.0321354894226973 0.0421399414617282 1.0 0.1761674171444059 2 Q53GQ0 1 +Transforming growth factor beta receptor binding 0.748506571087209 1.955279253313052 0.0505501185827936 1.0 0.1950861346391892 3 Q96AC1,Q9UNH7 2 +K63 linked polyubiquitin modification dependent protein binding 0.8161903318743147 1.943568577272128 0.0519474981645036 1.0 0.1987934985624858 4 Q8TAT6 1 +Amp activated protein kinase activity 0.7401911026809245 1.917315300363794 0.0551978872967557 1.0 0.2066150426135394 3 P17252 1 +Protein kinase c activity 0.7387694982287634 1.910812443945243 0.0560286879643827 1.0 0.208422888322652 3 P17252 1 +Sequence specific mrna binding 0.7784826372992719 1.900289074448754 0.0573951943375861 1.0 0.2119445181738354 6 P05455,P00374 2 +S adenosyl l methionine binding 0.7236475386542206 1.841418624784395 0.0655602355292723 1.0 0.2326878825779874 3 Q99873 1 +Dynein heavy chain binding 0.7231182795698831 1.8389827042458644 0.0659177300384792 1.0 0.2327507478162797 3 O43237,Q13409 2 +Structural constituent of postsynapse 0.7213261648745426 1.8307309519912316 0.0671407108225183 1.0 0.2352500609382357 3 P12814,Q12959 2 +1 phosphatidylinositol 4 kinase activity 0.720900323781416 1.828769378828956 0.0674341640466653 1.0 0.2356755223059478 3 Q9UBF8 1 +Carboxylic acid binding 0.4422697496717637 1.8188486198259095 0.0689345284060458 1.0 0.2390893770032476 38 Q05682,P04818,O60568,P07602,Q32P28,P29373,O15254,Q9NWT6,Q00169,P00374 10 +Pentosyltransferase activity 0.5511083667232187 1.8155624756199704 0.069437514168523 1.0 0.2396206408334422 19 P43490 1 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.7169864224044742 1.810726365869148 0.0701832194352292 1.0 0.24037752656566 3 Q01968 1 +2 oxoglutarate dependent dioxygenase activity 0.5733839959753702 1.7907023809849685 0.0733410674384655 1.0 0.2493232317387043 17 O60568,Q32P28,Q8IUF8,Q9NWT6,Q6NYC1 5 +Amide binding 0.364672442852149 1.785825985541876 0.0741274379087773 1.0 0.251372747363923 99 P24390,P45880,P07602,Q9H7Z7,Q00169,Q9NQP4,P21796,Q8WTV0,P00374,Q15392 10 +Hexokinase activity 0.6419826813974348 1.7705913401384186 0.0766286830585714 1.0 0.2573070975251049 2 P52789 1 +Iron ion binding 0.5147878931858633 1.7692233670150974 0.0768566061479614 1.0 0.257441443576301 23 O60568,Q32P28,Q9BU89,Q16850,Q9NWT6,Q6NYC1,Q15800 7 +Dna apurinic or apyrimidinic site endonuclease activity 0.705912004568104 1.7595378746488393 0.0784861930567886 1.0 0.259724841757972 3 P27695 1 +Translation repressor activity mrna regulatory element binding 0.7246416720699671 1.7539006758193971 0.0794475277873365 1.0 0.2611677771582877 7 P04818,Q9BPZ3,P00374 3 +3 5 dna helicase activity 0.6866397038645997 1.7474004153973255 0.0805679054834338 1.0 0.26343205372865 9 Q14566,P46063,P54132,P33992 4 +Dna binding bending 0.7512974599441791 1.723337549290827 0.0848275011797587 1.0 0.2718023901753912 5 P09429,Q00059 2 +Phosphatidylinositol monophosphate phosphatase activity 0.6980028935977773 1.722862199867206 0.084913447441655 1.0 0.2718023901753912 3 Q13614 1 +Fad binding 0.6316544792863985 1.7180587209548692 0.0857859051154799 1.0 0.2739549883641199 12 O15254,Q15392,Q9Y6N5 3 +H4 histone acetyltransferase activity 0.7611966323623003 1.711304874913873 0.0870248469142058 1.0 0.2753442038624989 4 Q86UY6 1 +Scaffold protein binding 0.5165422380839194 1.6778146121922457 0.0933832958634988 1.0 0.2867742560245379 21 P07602,O15111,P08670,Q9UQB8,Q8IWS0 5 +Structural molecule activity 0.2949071531440068 1.661734834682041 0.0965659533167353 1.0 0.2910084038069494 217 Q92665,Q8N5C6,P62841,Q8N1F7,Q9H2W6,Q9P015,Q03001,P55735,Q14651,P04350,P23258,P67936,Q12959,P61160,P09601,Q16540,P62081,P50914,P17096,P36551,O00231,P82933,P08865,P08670,P25398,P12270,P62917,P62899,P07197,P46782,P20700,P61513,Q02543,P62753,Q13813,Q7Z7H8,Q96EE3,P59998,P27635,P26038,Q8IUD2,Q9Y3D3,Q9BTX1 43 +Transmembrane transporter binding 0.4448076580450842 1.6540777361894592 0.098111719066863 1.0 0.2920981208096642 32 Q96PU5,P21796,Q99996,P27695,Q12959 5 +Four way junction dna binding 0.701615224950533 1.6480697511357942 0.099338358689522 1.0 0.2933050676824248 7 P52701,P25490,P26583,P09429,P54132 5 +Abc type transporter activity 0.7332270510279595 1.6445596876572253 0.1000606458933868 1.0 0.2948023330622364 5 P08183,Q9HD20,P28288 3 +Sulfur compound transmembrane transporter activity 0.7193869863492559 1.6387083891592653 0.1012740060615793 1.0 0.2960360061052381 6 Q70HW3 1 +Structural constituent of synapse 0.7318304485020066 1.638454528144565 0.1013269122854048 1.0 0.2960360061052381 5 Q8IUD2 1 +O acetyltransferase activity 0.6154075843535385 1.6347570176174575 0.1020999945127567 1.0 0.2960360061052381 2 Q8NF37 1 +Tubulin binding 0.3532752111896021 1.6342419765538256 0.1022080517429033 1.0 0.2960360061052381 102 Q9UQE7,Q03001,P50570,O75381,Q16512,O00139,P49354,P15311,O60313,Q8IWS0,O43663,O14737,P12270,Q92974,O00429,Q14166,P61758,Q9BW19,P07197,Q9NS87,P16949,Q08379,O75122,O15344,Q9BSJ2,Q9Y295 26 +Death receptor binding 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3046033992276 2 Q14790 1 +Metalloendopeptidase activity 0.580373899905781 1.6161802660194668 0.1060553441106315 1.0 0.3046033992276 14 Q99797,P22695,P42892,P14735,Q96TA2,O75844,Q10713 7 +Vitamin transmembrane transporter activity 0.71164950817553 1.6041041175094095 0.108691104452391 1.0 0.3082956792956019 6 Q9H2D1,P38435,P04062 3 +Damaged dna binding 0.4209291822951606 1.592587162937372 0.1112528352095763 1.0 0.3112391862512534 37 P18074,Q09472,P28340,P26583,P13051,P15927,P09429,P16104,P35244,P54132,Q9UBZ9,P19447,P20585,P54725,P27695,P29372 16 +D1 dopamine receptor binding 0.6678614097968859 1.5822824489210527 0.1135851055839349 1.0 0.3150032280364189 3 Q9Y5X3,Q15334 2 +7s rna binding 0.686678403053054 1.579031030476992 0.1143289397147122 1.0 0.3164255503215268 7 P49458,P09132,O76094 3 +Cytoskeletal protein binding 0.2855466799964888 1.5776031471403311 0.1146568089316948 1.0 0.3166932020895603 263 Q05682,P35580,Q5T1M5,P04062,Q16512,P67936,P49354,P47755,Q13561,O43663,Q92974,Q96EK5,Q9BW19,P07197,Q9NS87,P16949,Q9Y2J2,P30622,P60983,Q03001,O75381,O95235,P12814,Q12959,P52907,P15311,P27695,Q13464,Q01082,A0MZ66,P06753,Q9UKS6,Q9H0B6,O00429,P35579,P35241,Q6WCQ1,Q9UNH7,P51159,O15344,Q9UBN7,Q9UEY8,P59998,P38435,P26038,P35221,P35240,Q14651,Q8WXH0,Q9HB71,Q13485,Q16527,O60313,Q8IWS0,P29372,Q7KZI7,P33176,O14737,Q96AC1,Q92747,Q99661,Q5SNT2,Q14166,Q9NYL9,P61758,Q9P253,Q9Y496,O94887,Q9Y5X3,Q08379,Q9NPI6,Q9BR76,O43707,Q9P0K7,Q9UNF0,Q13813,Q09472,Q9UQE7,P50570,O00139,P61160,Q00839,Q13576,Q86TU7,P12270,Q9Y4I1,Q86UP2,O75122,P46939,Q5JTV8,Q9BSJ2,Q9Y295 92 +Bubble dna binding 0.658933502477571 1.5404283050203336 0.1234559863283775 1.0 0.3303412134177289 3 P09429 1 +Organic acid binding 0.4204699726267402 1.534526926894719 0.1249000740979413 1.0 0.3333965936523945 35 P04818,P00367,Q32P28,Q00169,P00374 5 +Phosphoric diester hydrolase activity 0.6098490461647202 1.5168237358320409 0.1293111925980081 1.0 0.3407962104805306 11 P27695,P09601,Q9NZC3 3 +Glycolipid binding 0.6731707035971727 1.5163720045184408 0.1294253138700309 1.0 0.3407962104805306 7 O14773,P07602,P55145,P50897,Q92643 5 +Oxidoreduction driven active transmembrane transporter activity 0.4340417529840316 1.5132717207308315 0.1302106528598976 1.0 0.3407962104805306 30 Q9P0J0,P51970,O75380,P14854,Q9UDW1,O43676,O75306 7 +Receptor tyrosine kinase binding 0.5284372981364454 1.51272970235029 0.1303483315998526 1.0 0.3407962104805306 17 P49354 1 +Thiolester hydrolase activity 0.5499121375026362 1.5045509905851522 0.1324395544873631 1.0 0.3436654361569895 15 Q9NUJ1,P50897 2 +Beta 2 adrenergic receptor binding 0.5885338907136495 1.4963062913122258 0.134573856398553 1.0 0.3452550248427296 2 Q15334 1 +Myosin ii binding 0.5885338907136495 1.4963062913122258 0.134573856398553 1.0 0.3452550248427296 2 Q15334 1 +Single stranded dna helicase activity 0.5587632100611604 1.4916762293104675 0.1357840436055803 1.0 0.3464136680440319 14 P33992,P51530,Q14566,Q8WVB6,P25205 5 +Atpase coupled transmembrane transporter activity 0.5361447703529965 1.4894809881294842 0.1363607560593194 1.0 0.3472383565079323 16 P28288,P08183,P06576,Q9Y5K8,Q9NRK6,Q9HD20,P16615 7 +Metallopeptidase activity 0.3949378678502214 1.476930099640409 0.1396943755209749 1.0 0.3530805536153388 41 P36551,P53582,P50579,P22695,Q96DE0,Q96TA2,O95630,Q10713 8 +Glycosyltransferase activity 0.3673661673178678 1.474744035567956 0.1402813723017124 1.0 0.353203587517691 54 Q10472,P43490,O60568,Q6ZXV5,P46976,P04062,Q13126,Q9H6U8,Q2TAA5 9 +Anion transmembrane transporter activity 0.3959197163461728 1.452091903534372 0.1464760528874826 1.0 0.3615715179384707 40 P45880,P53007,Q9H2D1,Q9UBX3,P21796 5 +Exogenous protein binding 0.5495829570420835 1.4385549475632415 0.1502766587227171 1.0 0.3682987879250849 14 Q14108,P35613 2 +Histone arginine n methyltransferase activity 0.6365072821935029 1.4349641578145538 0.1512973114762128 1.0 0.3701048050829588 3 Q99873 1 +Potassium channel regulator activity 0.6537290008999515 1.4258808438410142 0.1539027397839936 1.0 0.372520765908253 7 Q96PU5,Q99996 2 +Glucosyltransferase activity 0.61648334276439 1.4017473250844807 0.1609907130942018 1.0 0.3870427006618702 9 P04062,O60568,P46976 3 +Single stranded dna 3 5 exodeoxyribonuclease activity 0.570020901761719 1.4004830773315855 0.1613687074903502 1.0 0.3871718550994393 2 Q07864 1 +Voltage gated anion channel activity 0.6657524225905389 1.397621495267858 0.1622267599540343 1.0 0.3885501068829144 6 P21796 1 +3 5 exodeoxyribonuclease activity 0.6752682866986964 1.389625345298021 0.1646426752279395 1.0 0.3929624826868939 5 P28340,P49959,P27695 3 +Kinesin binding 0.585364509994232 1.3878640562456996 0.165178444754833 1.0 0.3935555988071673 11 Q86UP2,O43663,A0MZ66,Q9NPI6,O60333,Q9H0B6,Q96EK5 7 +Mdm2 mdm4 family protein binding 0.6609446794798475 1.3759050120204264 0.1688510433145933 1.0 0.3995266482573279 6 Q96JB5,P62841 2 +Lipopolysaccharide binding 0.6606314242071303 1.374489691797921 0.169289708274982 1.0 0.3998739660978024 6 Q8WTV0 1 +Microtubule binding 0.3352353744965674 1.3455379522745554 0.1784515737297849 1.0 0.406786449267563 77 P49354,O43663,Q08379,O75122,P15311,O60313,Q9Y295,O15344,Q03001,Q92974,O75381,O00429,P50570,Q9BSJ2,O00139,Q9BW19,P07197,Q9NS87 18 +Atpase binding 0.4288152009384309 1.340080361016488 0.1802192201566188 1.0 0.4077008805023243 27 P35241,P15311,P55769,Q93050,Q5JTV8,P40855,Q8TAT6,Q9Y487 8 +Phospholipase binding 0.6162155351084164 1.339264616367074 0.1804845433968871 1.0 0.4077008805023243 3 P20700 1 +Protein kinase b binding 0.5574798447297754 1.335456144923552 0.1817270995141382 1.0 0.4077008805023243 2 O95999 1 +Protein adp ribosylase activity 0.614787734360798 1.3325257789773917 0.1826874761854886 1.0 0.4077008805023243 3 P09874 1 +Cyclic nucleotide dependent protein kinase activity 0.6730781907809497 1.3321064731318248 0.1828252035509541 1.0 0.4077008805023243 4 P54619 1 +Camp dependent protein kinase activity 0.6730781907809497 1.3321064731318248 0.1828252035509541 1.0 0.4077008805023243 4 P54619 1 +Translation repressor activity 0.6156944352044277 1.3319211021156732 0.1828861160012835 1.0 0.4077008805023243 8 P04818,Q9BPZ3,P00374 3 +Monosaccharide binding 0.4395613755147891 1.330360456227126 0.1833995368539343 1.0 0.4078853335874837 25 Q32P28 1 +Supercoiled dna binding 0.6604686834791522 1.3241854206930004 0.1854414716092927 1.0 0.4110919354445485 5 P09429 1 +Amyloid beta binding 0.5999688508569667 1.3196549319345965 0.1869502535110463 1.0 0.4137671200486809 9 O00264,Q9NQP4,P30533,P61758,Q8WTV0 5 +Channel regulator activity 0.5076174232039268 1.315425414274311 0.1883669689203766 1.0 0.415559979743826 16 Q96PU5,Q99996,Q12959 3 +Organic anion transmembrane transporter activity 0.429669839397079 1.3108583437324537 0.1899056266923686 1.0 0.416685810823061 26 Q9H2D1,P53985,P53007,Q9UBX3 4 +Histone kinase activity 0.5832814125139877 1.3036675681505594 0.1923469518571088 1.0 0.4209436460638772 10 P17252,O14757,P54646,P24941 4 +Nucleotidase activity 0.6540733617754662 1.2958932434153847 0.1950122673526917 1.0 0.4219849384903428 5 Q5TFE4 1 +Cytoskeletal motor activity 0.4132942141861673 1.2954534002108449 0.1951638668692816 1.0 0.4219849384903428 29 Q9Y4I1,Q9Y496,P35580,Q9UQE7,P33176,O60333,P35579,Q99661,Q13409,O00139,Q9BW19,O95235,Q9NS87 13 +Dna helicase activity 0.3795608789086823 1.2951063609955191 0.1952835408780127 1.0 0.4219849384903428 40 P18074,P46063,Q12873,Q9H2U1,P33992,P54132,Q86WJ1,P19447,Q9Y4B4,Q8IYB8,P33991,P51530,Q14566,Q8WVB6,P25205 15 +Microfilament motor activity 0.606035048146327 1.2852279784244456 0.1987126293606227 1.0 0.4287185861796112 8 Q9Y4I1,P35580,O94832,P35579 4 +Pseudouridine synthase activity 0.6482471227927478 1.2701178711066865 0.2040426466989644 1.0 0.4374623254735231 5 O95900,Q9Y606 2 +Signaling receptor regulator activity 0.4786696025052019 1.2677811365379943 0.2048761203713391 1.0 0.4378787596080104 18 P49354,P14174,P43490 3 +Protein tyrosine kinase binding 0.454416585547784 1.2508495966838875 0.2109893559966247 1.0 0.4478975670627095 21 P49354 1 +Nadplus kinase activity 0.541057031949842 1.250276897099999 0.2111984148339492 1.0 0.4478975670627095 2 Q53H12 1 +G quadruplex dna binding 0.6433830288605079 1.2486017238929237 0.2118107815202914 1.0 0.4485019639610498 5 Q9H2U1,Q92878,P54132 3 +Isopeptidase activity 0.5849054765631185 1.2447078899549238 0.2132391446927819 1.0 0.4508296731930729 9 O95630 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.641982694502089 1.2424082497361069 0.2140859733617164 1.0 0.4519226248159499 5 P36551 1 +Carboxylic ester hydrolase activity 0.3872098075322662 1.2364648270792975 0.2162858320868901 1.0 0.4551637326559746 35 Q8NCG7,Q9NUJ1,P35790,Q15165,Q9BW92,Q9NZC3 6 +Phosphatidylserine binding 0.5693695638511309 1.2323525446386543 0.2178174196605296 1.0 0.4574925408708691 10 Q14108,P09429,Q8WTV0 3 +P type potassium transmembrane transporter activity 0.5374738727978563 1.231702292186044 0.2180603132764069 1.0 0.4574925408708691 2 P05023 1 +Anion channel activity 0.5809818978218498 1.2251882527435156 0.2205042995271404 1.0 0.4619126763794838 9 P21796 1 +Peptide n acetyltransferase activity 0.4923846322475048 1.2222124285830234 0.2216273050552841 1.0 0.4635563479782279 16 Q09472,Q9BXJ9,O60318,Q86UY6,Q92993,P41227 6 +Dopamine receptor binding 0.6256552281037653 1.2163600704414448 0.22384778762027 1.0 0.4667754475491171 6 P50570,Q9Y5X3,Q14344,Q15334 4 +Molecular transducer activity 0.3810542074207724 1.2026890039530207 0.2290966906803055 1.0 0.4741124867553151 36 O15173,Q9NWH9,Q93034,Q9UL03,Q6NYC1,Q14108,Q9UNN8,Q8WTV0,Q4VCS5 9 +Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor 0.5757799936111274 1.199316324785398 0.2304049697559618 1.0 0.4761007670673721 9 P30043,P00374,Q96C36 3 +Cholesterol binding 0.5213089861655246 1.193519336634711 0.2326660437905054 1.0 0.4790890421924471 13 Q14108,P21796 2 +Histone serine kinase activity 0.5840986846073398 1.1877368461923257 0.2349371023882147 1.0 0.4815741997064759 3 P54646 1 +Collagen binding 0.5723252779920925 1.1821408898537242 0.2371498021212303 1.0 0.484195572140217 9 O75718,Q32P28,Q53GQ0 3 +Glucocorticoid receptor binding 0.5273215885338975 1.179121473180476 0.2383498092072264 1.0 0.485538242585645 2 Q04917 1 +Channel inhibitor activity 0.6273926253699167 1.17792096683142 0.2388281154688578 1.0 0.485538242585645 5 Q96PU5 1 +Structural constituent of cytoskeleton 0.3915439999479569 1.176919028038876 0.2392278265275549 1.0 0.485538242585645 31 P08670,Q14651,P23258,P04350,P59998,P26038,P07197,Q13813 8 +Active ion transmembrane transporter activity 0.3726535076667568 1.173259321464797 0.2406918296505891 1.0 0.485538242585645 38 P53007,Q9Y5K8,Q9HD20,P12235,Q9UDW1,P14854 6 +Demethylase activity 0.5446151306591009 1.172498226055974 0.240997083911123 1.0 0.485538242585645 11 Q8IUF8,Q16850,Q6NYC1,Q9Y4C1 4 +Sterol binding 0.4839444057946346 1.1705672008323165 0.241772787598208 1.0 0.4856726085183945 16 Q14108,P21796 2 +Oxidative rna demethylase activity 0.5774416434788481 1.156390255820244 0.2475215654688796 1.0 0.4948609620189768 3 Q6NYC1 1 +N acetyltransferase activity 0.4612791895197159 1.155413576878925 0.2479211047243057 1.0 0.4948609620189768 18 Q09472,O75448,Q9BXJ9,O60318,Q86UY6,Q969G3,Q92993,P41227 8 +1 phosphatidylinositol binding 0.6120339588484358 1.1548474410423477 0.2481529057715599 1.0 0.4948609620189768 6 Q8WTV0 1 +Dynein complex binding 0.594902646125423 1.15119519174588 0.2496519428823345 1.0 0.4949683961632391 7 Q9UBN7,P12270,Q9UQE7 3 +Molecular function activator activity 0.4979762117413209 1.138765384611954 0.254801023141715 1.0 0.5037191943782823 14 Q5JTV8,Q6NYC1,Q96KC8,Q8IXB1 4 +Gtpase inhibitor activity 0.6081801754273554 1.1374667381450856 0.2553432217689597 1.0 0.5038518730447422 6 Q13576,O94813 2 +N acyltransferase activity 0.4378671383294763 1.1363517051624792 0.2558093993504249 1.0 0.5038518730447422 21 Q09472,Q96G23,Q9BXJ9,O60318,Q86UY6,Q92993,P41227 7 +Phospholipid binding 0.3177106609973896 1.1298859253663185 0.258524295332408 1.0 0.5066928249004279 89 P45880,Q9UNH7,P07602,Q15075,O60313,P09429,Q9UKS6,Q00169,P50897,Q9P2R3,P21796,Q9UNF0,Q06481,Q14108,Q8WTV0,Q9NS86 16 +Oxidoreductase activity acting on the ch nh group of donors 0.543991608939227 1.1024516370184436 0.2702653730895679 1.0 0.5219232990423014 10 P30043,P00374,Q96C36 3 +Microtubule motor activity 0.4428309180468719 1.1019445079075405 0.2704857973138934 1.0 0.5219232990423014 19 Q9Y496,Q9UQE7,P33176,Q99661,Q13409,O00139,Q9BW19,O95235,Q9NS87 9 +Medium chain fatty acid coa ligase activity 0.5120931621379593 1.10046516760863 0.2711294981917347 1.0 0.5224295534777448 2 Q96CM8 1 +Protein homodimerization activity 0.2680597752053945 1.0906618861720727 0.2754216873608688 1.0 0.5299546512421212 179 P34897,P23381,P49815,Q15075,Q9BY67,Q13555,Q12904,P46976,P42892,Q8N4J0,Q04837,Q8IYB8,Q14108,O75569,Q99623,Q15257,P12814,P67936,Q92530,Q9HB71,Q9NRG1,Q13043,P07602,O15111,Q13485,Q13257,P09601,Q99816,Q9BXR0,Q9HAV7,P29372,P51659,P49591,P36551,P28288,P48426,O60749,P12270,O00429,P51116,P23246,Q06481,Q9H8V3,Q9NWT6,P35579,Q9BW92,Q9NZJ7,Q9GZZ9,P51648,P04818,Q8TBA6,Q8TCT9,Q9UNH7,O43707,O00264,O43708,Q9NRK6,P14373,O15344,P19623,O94813,P54132,Q96DE0,P14735,Q01664,P20585,Q8IY95 67 +Transcription coregulator binding 0.3881087534517019 1.0888563030373528 0.2762172583766049 1.0 0.5307400336268565 29 Q9UQB8,P17096 2 +Molecular function inhibitor activity 0.5518387484245384 1.080490391235291 0.2799238633555574 1.0 0.5363576123036555 9 Q96PU5 1 +Dna n glycosylase activity 0.6031504373023436 1.0711140813360918 0.2841181374429973 1.0 0.5436338663364613 5 P13051,P27695 2 +Nadh dehydrogenase activity 0.4281099551320101 1.0689597463966305 0.2850878081329884 1.0 0.5447284478970629 21 Q9P0J0,O75380,P51970,O43676,O75306 5 +Phospholipid transporter activity 0.576757612041605 1.0667631345574855 0.2860788096118662 1.0 0.5458606812928368 7 P08183,Q00169,Q8NB49 3 +Ligase activity forming phosphoric ester bonds 0.5578457431917705 1.0644087405464966 0.2871435759323204 1.0 0.5463288058855862 3 P18858 1 +Polynucleotide adenylyltransferase activity 0.5046282472379895 1.0620484325338428 0.2882136986040482 1.0 0.5463288058855862 2 Q9NVV4 1 +Protein serine threonine kinase activator activity 0.5233016447445098 1.0601488862107566 0.2890768704893942 1.0 0.5470101002354559 11 Q13043 1 +Endodeoxyribonuclease activity 0.509532586516169 1.0547111373317222 0.2915574565431491 1.0 0.5482656267932224 12 P51530,Q9Y2C4 2 +Prenyltransferase activity 0.5578039853631718 1.0525602874047266 0.2925425661581893 1.0 0.5482671896535148 8 P49354,P37268 2 +Dna directed dna polymerase activity 0.5731665683698689 1.0501033831079416 0.2936705834713002 1.0 0.5496293707044828 7 P28340,Q9UBZ9,P09884,Q9NR33,Q9Y2S7 5 +Microtubule minus end binding 0.597799484425486 1.0476313559048525 0.2948084850405577 1.0 0.5502556192173896 5 Q14980,Q9UPN3,Q9BSJ2 3 +Nedd8 transferase activity 0.5010450880860016 1.0436506579103637 0.2966470462801669 1.0 0.5515990594614963 2 P61081 1 +Flavin adenine dinucleotide binding 0.3757893430070073 1.043458187516995 0.2967361363672429 1.0 0.5515990594614963 31 O15254,A1L0T0,Q9Y6N5,Q14534,Q709F0,Q15392 6 +Ribosome binding 0.3531915638211994 1.0420322803676147 0.2973967131254706 1.0 0.5520779091895595 40 P04844,Q7Z739,P41227,Q9BXJ9,P09132,P42345,P08865,O76094,Q9UHB9,Q92552,Q96A33,Q99543,Q9UM00 13 +Protein demethylase activity 0.553050608488006 1.0297646276658554 0.3031205092229476 1.0 0.5604252329763 8 Q8IUF8,Q6NYC1 2 +Proton transporting atp synthase activity rotational mechanism 0.5166256776702696 1.0250961122121816 0.3053178397931808 1.0 0.5629682914086914 11 P18859,P06576,P56134,O75964,P25705 5 +Proton channel activity 0.5166256776702696 1.0250961122121816 0.3053178397931808 1.0 0.5629682914086914 11 P18859,P06576,P56134,O75964,P25705 5 +Protein n terminus binding 0.3373415715003061 1.0217569594457518 0.3068959449260398 1.0 0.5637039946024706 48 P18074,Q9UJW0,P50542,P51532,P35754,P60228,P15927,Q96FZ7,Q9UBU8,O75381,P40855,P19447,Q969G3,P09874,Q99623,P51608 16 +Quinone binding 0.5657691059083866 1.0158522761412667 0.3096997377886623 1.0 0.5679901482871049 7 Q9Y6N5 1 +Oxidoreductase activity 0.2647420869456676 1.013658011455903 0.3107459661364182 1.0 0.5684245287064875 240 P30519,Q32P28,Q6IAN0,O43676,Q9UHG3,Q8NBX0,P00374,Q15800,Q15392,Q9P0J0,Q9H7Z7,P09601,Q8IUF8,Q16850,Q709F0,P53004,O00625,P27695,P36551,P00367,Q9BU89,Q9Y6N5,P14854,O43169 24 +Dna replication origin binding 0.5012752825387439 1.0099563557369453 0.312516200565623 1.0 0.5701027893141193 12 Q99741,O43913,P33992,O95251,P09884,Q9UBD5,Q9BQ67 7 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.4871018829119847 1.0015989870048616 0.3165373104354589 1.0 0.5765889197511991 13 Q9H7Z7,Q15392 2 +Protein arginine n methyltransferase activity 0.5859347486476941 0.9957304572356688 0.3193811274448312 1.0 0.5784870781378586 5 O14744,Q99873 2 +Translation regulator activity nucleic acid binding 0.3146188232073853 0.99363901435786 0.3203986430587038 1.0 0.5789652175305022 69 P46199,P04818,Q9ULC4,P34897,P41567,Q9NR50,Q9BPZ3,Q7Z478,P57772,P55010,Q13144,Q9H074,P20042,P00374,P29692 15 +Histone threonine kinase activity 0.5852876156733104 0.9929071961615769 0.3207551825588695 1.0 0.5789652175305022 5 P17252,O14757,Q16512 3 +Endoribonuclease activity 0.4060425376394319 0.9891332043806196 0.3225979737745015 1.0 0.5807611354416125 23 Q9BQG2,P27695,Q96DE0,Q9Y2C4 4 +Tau protein kinase activity 0.583335617724184 0.984396377913245 0.3249206582913762 1.0 0.583528157133271 5 Q13464,Q7KZI7 2 +Single stranded dna binding 0.3172428121750706 0.982842340862672 0.3256850393974373 1.0 0.583528157133271 62 P67809,Q04837,Q96FZ2,P25205,P26583,P15927,Q00839,Q15366,Q96AE4,P46063,P35244,Q96RR1,Q9Y3Z3,P33991,Q14566,Q9H2U1,P33992,P09429,P54132,P09884,P54725,Q15631 22 +Lysophospholipid acyltransferase activity 0.5734505624538846 0.9816655380389376 0.3262646484409384 1.0 0.583528157133271 6 Q96N66 1 +Acylglycerol o acyltransferase activity 0.5734505624538846 0.9816655380389376 0.3262646484409384 1.0 0.583528157133271 6 Q96N66 1 +Poly g binding 0.5661728657227028 0.949293500137961 0.3424713584617134 1.0 0.6049921206218811 6 Q96EZ8,O14979 2 +Peptide binding 0.3104249621335068 0.9352392663598368 0.3496650066663611 1.0 0.614409670652288 68 P24390,P50542,Q9H7Z7,O00264,Q9NQP4,P42892,P40855,Q13427,P61758,Q8WTV0,Q15392 11 +Alcohol binding 0.4452327701035499 0.934958114833236 0.3498098854808646 1.0 0.614409670652288 16 Q14108,P21796 2 +Oxidoreductase activity acting on a heme group of donors 0.5478248546127422 0.9332423711690292 0.3506948423326648 1.0 0.6149536636160389 7 P16435,P14854 2 +Ccr5 chemokine receptor binding 0.4792475365780923 0.9325088125521463 0.3510736345129992 1.0 0.6149536636160389 2 P48681 1 +Inorganic anion transmembrane transporter activity 0.4356908590515194 0.9317490752870092 0.3514662179644952 1.0 0.6149536636160389 17 P45880,P21796 2 +Pre mrna intronic binding 0.559258144834986 0.9186583117750796 0.3582743214244464 1.0 0.6247231612003384 6 Q09472 1 +Atpase coupled cation transmembrane transporter activity 0.4842778780250517 0.9183840966775392 0.3584178136521649 1.0 0.6247231612003384 12 Q9Y5K8,P16615,Q9HD20 3 +Poly a binding 0.4777457762730568 0.883450082040936 0.376993141752717 1.0 0.6472188022571708 12 Q00839,P31483,O14979 3 +Kinase activator activity 0.4086488110934609 0.8766140268799499 0.3806963177687374 1.0 0.6511285335120728 19 Q7KZI7,Q13043 2 +Ubiquitin protein transferase inhibitor activity 0.5203830114019146 0.8745252431375222 0.3818322793122852 1.0 0.6522571354835796 8 P62913,P62841,P62081 3 +Cell cell adhesion mediator activity 0.4238575756383063 0.8586899248777412 0.3905116104841075 1.0 0.6635645761865686 17 Q9UQB8 1 +Cyclin dependent protein serine threonine kinase activator activity 0.4643177067781465 0.8574120887472713 0.3912171806822173 1.0 0.6635645761865686 2 O75909 1 +Camp dependent protein kinase inhibitor activity 0.4640191101821473 0.8559208318647358 0.3920415713255401 1.0 0.663864034292613 2 P10644 1 +Nuclear receptor activity 0.4634219169901565 0.8529396922726428 0.3936927487960417 1.0 0.6650543352041642 2 P40763 1 +Notch binding 0.5606942652081921 0.8504111793029323 0.3950965229324563 1.0 0.6657838086315685 4 Q9H3F6 1 +Translation activator activity 0.5604128640413295 0.849236343781929 0.3957497938033383 1.0 0.665940845011727 4 Q9H074 1 +Deoxyribonuclease activity 0.4038531082237763 0.8453863411558701 0.3978951681291138 1.0 0.6672171117954541 19 P51530,P27695,Q9Y2C4 3 +Protein carrier chaperone 0.5135884961307633 0.8426573118190728 0.3994201280494875 1.0 0.6689554711831271 8 Q9P0I2,Q15006 2 +Cation channel activity 0.4025191227249404 0.8367241079378194 0.4027476648185017 1.0 0.672103041894477 19 P18859,P06576,Q93034,O75964,P56134,P25705,P24539,Q9UM00 8 +Map kinase kinase kinase activity 0.4601373544341597 0.836576950538108 0.4028304061582626 1.0 0.672103041894477 2 Q13546 1 +Endonuclease activity 0.336052080285213 0.8343535084381083 0.4040818075051777 1.0 0.672103041894477 38 Q9Y2C4,Q96DE0,P51530,Q9BQG2,P27695 5 +Secondary active transmembrane transporter activity 0.3977061772763448 0.8315693881083803 0.4056520469568787 1.0 0.6728127171076561 20 P53985,P53007,Q9UBX3 3 +Oxidoreductase activity acting on the ch ch group of donors 0.3517892767229543 0.8279196650919348 0.4077159972479609 1.0 0.6742859966438656 30 P36551,Q9H7Z7,Q709F0,P53004,Q15392 5 +Phosphatidylinositol phosphate 4 phosphatase activity 0.5065485431610647 0.8277562416457763 0.4078085608011368 1.0 0.6742859966438656 3 Q01968 1 +Cargo receptor activity 0.5103190429625206 0.8273885736175113 0.4080168549034777 1.0 0.6742859966438656 8 Q14108 1 +Inositol polyphosphate 5 phosphatase activity 0.5054639053547614 0.8228528890078441 0.4105916560246916 1.0 0.6761971185528866 3 Q10713 1 +Passive transmembrane transporter activity 0.3497014034383761 0.8108659655226723 0.4174426472028629 1.0 0.6803882342499507 30 P18859,P51790,P45880,P06576,Q93034,O75964,Q4KMQ2,P21796,P25705,P56134,P24539,Q9UM00 12 +Phosphoric ester hydrolase activity 0.2987721819598056 0.7940955397994088 0.4271398139752764 1.0 0.6917039540734382 68 Q12959,Q5TFE4,Q969T7,Q9H993,P09601,Q8IV08,Q9ULE6,Q96DE0,P27695,Q10713,Q9NZC3 11 +Rna polymerase activity 0.3876628478921305 0.7929809137544211 0.4277889429410024 1.0 0.6919372512741125 21 Q13503 1 +Ribosomal small subunit binding 0.4467245533451163 0.7792833721328086 0.4358128074196516 1.0 0.7016022869153029 13 P46199,Q96EY7,P41567 3 +Poly purine tract binding 0.4188002466486266 0.7771093987158948 0.437094229323083 1.0 0.7020153507299224 16 Q96EP5,Q96EZ8,Q13310,Q00839,P31483,O14979 6 +Magnesium ion binding 0.2888915569141542 0.7709450923770164 0.4407394778223268 1.0 0.7062141340544886 81 O75695,P78362,Q969T7,Q13043,P24941,O60313,A1L0T0,Q9H773,Q96DE0,Q8NB49,Q9BQG2,Q7KZI7 12 +Phosphatidylinositol kinase activity 0.5398089549784 0.7640419615040487 0.4448422370627778 1.0 0.7086440288093089 4 Q9UBF8 1 +Translation regulator activity 0.2887535963804573 0.7597629590164502 0.44739628765549 1.0 0.71072590606424 83 P46199,P04818,Q9ULC4,P41567,P34897,P55010,Q9BPZ3,P51116,Q13144,P27635,Q9H074,P20042,P00374,P29692 14 +Cyclin dependent protein kinase activity 0.475660780495267 0.7594116831968568 0.4476063268012387 1.0 0.71072590606424 10 Q00534 1 +Atpase activator activity 0.442461645919723 0.7562897856286714 0.449475470888143 1.0 0.71072590606424 13 Q5JTV8,Q96KC8,Q8IXB1 3 +Ubiquitin conjugating enzyme binding 0.4947489711413327 0.7553470654098519 0.4500407657256038 1.0 0.71072590606424 8 Q9BTE7,Q96GG9 2 +Sirna binding 0.488525788131953 0.7470440881418333 0.4550369484013239 1.0 0.7125847173864718 3 P51608 1 +Cell adhesion mediator activity 0.3876575513230421 0.7410626519144302 0.4586554534990643 1.0 0.7151136079405893 19 Q9UQB8 1 +Cullin family protein binding 0.5160767548713862 0.731094188307318 0.4647216239027953 1.0 0.7209598627200529 6 Q9NXV2,Q9BTE7,Q96GG9 3 +Dynactin binding 0.5239842150829901 0.7310678289246411 0.4647377234833185 1.0 0.7209598627200529 5 Q9UNH7 1 +Vitamin binding 0.3069974819485256 0.726373927629831 0.4676095700527856 1.0 0.7228007954277035 49 P04818,O60568,Q32P28,P04062,P38435,P00374 6 +Oxidized dna binding 0.5146219177000806 0.7249193039471181 0.4685015374743071 1.0 0.7228007954277035 6 P52701,P54132,P20585 3 +Organophosphate ester transmembrane transporter activity 0.456143327460391 0.7143463236545301 0.475013054285178 1.0 0.7267679271300471 11 Q9H2D1,Q9BSK2 2 +Nucleotide transmembrane transporter activity 0.456143327460391 0.7143463236545301 0.475013054285178 1.0 0.7267679271300471 11 Q9H2D1,Q9BSK2 2 +Voltage gated channel activity 0.4652964368028903 0.7091449075282827 0.4782345575432876 1.0 0.7267679271300471 10 P21796 1 +Cyclin binding 0.4210671526669492 0.7009613638355792 0.4833271272291837 1.0 0.7300531028709831 14 Q96JB5,Q00534,P24941 3 +Dna secondary structure binding 0.4207304682714216 0.699114873283534 0.4844802442513851 1.0 0.7301847465614936 14 P25490,Q14103,P26583,P09429,P17096 5 +Aryl hydrocarbon receptor binding 0.4305762914302788 0.6923731118496036 0.488703046931433 1.0 0.7341262876053326 2 O00170 1 +Protein prenyltransferase activity 0.5135198808709701 0.6879565554017697 0.4914801401648718 1.0 0.735877368334289 5 P49354 1 +Signaling receptor binding 0.2488142528204915 0.6869944136260054 0.4920862487612574 1.0 0.7359805248940203 178 P43490,Q15648,P35240,Q9BY67,Q6P3W7,P51572,Q03001,P04062,O75381,P50570,P30533,Q99996,P49354,Q13043,O15111,P26583,Q9H2J4,Q9H3F6,P27695,P17096,P14174,P06576,Q9NWT6,P17252,Q9UBS4,Q9UJZ1,P46939,Q9UNH7,P09429,Q15036,P26038 31 +Nucleobase containing compound transmembrane transporter activity 0.4272708574612697 0.6754081251958328 0.4994165046995387 1.0 0.7436963167808348 13 Q9H2D1,Q9BSK2 2 +Poly pyrimidine tract binding 0.4078527133839831 0.669178340699405 0.5033817210020191 1.0 0.7471154013621086 15 Q00839,Q96EZ8,P05455,O43347 4 +Rna polymerase ii general transcription initiation factor activity 0.5087269586708201 0.6684209228816256 0.5038649434973868 1.0 0.7471154013621086 5 Q92759,P35269,Q00403 3 +G protein alpha subunit binding 0.5160786497660507 0.6683755616347288 0.5038938911376558 1.0 0.7471154013621086 4 Q02818,P80303 2 +Tumor necrosis factor receptor binding 0.5082253942082018 0.6663846949778872 0.5051652426121631 1.0 0.7473827023527684 5 Q12931,Q14790 2 +Hydrolase activity acting on ester bonds 0.2475120286604394 0.6617167764980468 0.508152750927553 1.0 0.7488178853926483 178 Q9Y2C4,Q9NUJ1,P35790,Q9BQG2,Q9NZC3,Q9BTE6,Q12959,Q5TFE4,P09601,Q8NHP8,Q15165,P51530,Q9Y3B2,P27695,Q10713,O15091,O43681,Q8IV08,Q9BW92,Q969T7,Q9H993,Q8NCG7,P50897,Q9ULE6,Q96DE0,Q9NUQ7 26 +Estradiol 17 beta dehydrogenase activity 0.5070083011270307 0.6614501488627994 0.5083236743043387 1.0 0.7488178853926483 5 Q53GQ0,P51659 2 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.5070083011270307 0.6614501488627994 0.5083236743043387 1.0 0.7488178853926483 5 Q53GQ0,P51659 2 +Calcium dependent protein kinase activity 0.512579489530405 0.6545372373495217 0.5127657446641596 1.0 0.7506642570133483 4 P17252 1 +Catalytic activity acting on dna 0.2829855166649623 0.6500533562400773 0.5156577570278704 1.0 0.7523441183473722 93 P52701,Q9UQE7,Q9Y2C4,P49959,Q8IYB8,Q96FZ2,P25205,P28340,P13051,Q86WJ1,Q9NR33,P51530,P27695,Q9Y2S7,P29372,O14981,P46063,Q12873,Q8IV08,P19447,Q96RR1,P33991,Q14566,Q9UNY4,P18074,P51532,Q9H2U1,P33992,P54132,Q9UBZ9,P09884,Q9Y4B4,Q8WVB6 33 +Lipid binding 0.2736628849818406 0.6481312349524649 0.516900073261594 1.0 0.7533543620940253 135 Q15075,P04062,P21796,Q14108,Q8WTV0,P45880,P07602,O60313,O15254,Q00169,O15173,Q9UKS6,O00429,Q06481,Q9UNH7,O00264,P09429,P50897,Q9P2R3,P38435,Q9NS86 21 +Hexosyltransferase activity 0.3151025753397712 0.6464693562044892 0.517975436480377 1.0 0.7541193921127699 38 Q10472,O60568,Q6ZXV5,P46976,P04062,Q13126,Q9H6U8 7 +Atp dependent activity acting on dna 0.2886147329005471 0.6390382155674691 0.5227980714221234 1.0 0.7595697783637461 59 P52701,Q9UQE7,Q92499,P49959,Q92878,Q8IYB8,P25205,O14646,P28370,Q86WJ1,P51530,O00571,O14981,P46063,Q12873,P19447,Q96RR1,P33991,Q14566,Q9UNY4,P18074,P51532,Q9H2U1,P33992,P54132,P35251,Q9Y4B4,Q8WVB6 28 +3 hydroxyacyl coa dehydrogenase activity 0.4796955465689432 0.6306915879225427 0.5282422003945448 1.0 0.7649069653065957 7 Q53GQ0,Q08426 2 +Membrane insertase activity 0.4915391822138414 0.6286252818790723 0.5295944048095571 1.0 0.7649069653065957 6 Q15006 1 +Gated channel activity 0.4349640163299643 0.6105535880262946 0.5414951565330055 1.0 0.7759920130232402 11 P21796 1 +Double stranded methylated dna binding 0.4565146212050215 0.6086994918356148 0.5427236439211167 1.0 0.7769398037324241 3 Q9UIS9 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3468817814636473 0.6069953188846591 0.5438540187189753 1.0 0.7777453086064678 24 Q9P0J0,O75380,P51970,O43676,O75306 5 +Translation initiation factor activity 0.3063826881835578 0.6056993307126528 0.5447144285421284 1.0 0.7781634693458978 40 P46199,Q9ULC4,P41567,P55010,P20042 5 +Oxidoreductase activity acting on a sulfur group of donors 0.3334656959610649 0.6010442590256695 0.5478105080069975 1.0 0.780145941756327 27 Q9H3N1,P35754,Q9Y6N5,Q9UHG3,P00390 5 +Methyl cpg binding 0.4389244885190941 0.5847944644106278 0.5586859269292233 1.0 0.7898861918400784 10 O14744,P51608,Q99873,Q9UIS9 4 +General transcription initiation factor activity 0.46834160705174 0.5829638280013419 0.559917650909062 1.0 0.7908115275725927 7 Q92759,P35269,Q00403,Q9NYV6 4 +Metalloexopeptidase activity 0.3572608047844824 0.5714785661238676 0.567675285482728 1.0 0.7980509521894804 20 Q96DE0,P36551,P53582 3 +Microtubule plus end binding 0.4170812286295982 0.5710644290961884 0.5679559696239003 1.0 0.7980509521894804 12 O75122,P30622,Q14980,Q99661,Q03001 5 +Tumor necrosis factor receptor superfamily binding 0.4760950671769857 0.5662566229041535 0.5712193431546813 1.0 0.7993569970601769 6 Q12931,Q14790,Q12933 3 +14 3 3 protein binding 0.4891120079866382 0.56386914350686 0.5728431911178651 1.0 0.8003181325993253 4 P78362 1 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.4405048926576871 0.5520547961974039 0.5809108111945331 1.0 0.8071478816800308 9 O60885,Q00534,Q9NYV4 3 +Amp binding 0.4585043851476039 0.5424846273808231 0.5874846946758665 1.0 0.8129205094052785 7 P54619 1 +Ligase activity forming carbon oxygen bonds 0.3077624978904366 0.5419815611653014 0.5878312082796024 1.0 0.8129205094052785 35 Q9BTE6,P54136,P49591,Q9HA77,Q9Y285,P49589,A2RTX5,P41250,P23381,P49590,Q5T160,P47897,Q9BW92 13 +Diphosphotransferase activity 0.4396654719235201 0.539244153517806 0.5897183977207627 1.0 0.8136094711756746 3 Q14558,O60256 2 +Ribose phosphate diphosphokinase activity 0.4396654719235201 0.539244153517806 0.5897183977207627 1.0 0.8136094711756746 3 Q14558,O60256 2 +Signal recognition particle binding 0.4726035949084024 0.5263448131977038 0.5986486520405219 1.0 0.8193293239715435 5 P49458,O76094 2 +Metalloaminopeptidase activity 0.4164083083201393 0.523046826999598 0.6009416669506569 1.0 0.8216467901421156 11 P53582 1 +O methyltransferase activity 0.4323316989374614 0.5165644523576092 0.6054602358041277 1.0 0.8235796485058994 9 Q9H993,O60725 2 +Mutlalpha complex binding 0.4336917562723869 0.5152942986483771 0.6063473824005168 1.0 0.8235796485058994 3 P52701,P43246 2 +Mhc protein binding 0.4390582381687536 0.5107378870706089 0.6095346074036883 1.0 0.8244438213031886 8 P51572,P06576 2 +Gtp dependent protein binding 0.4390390782239204 0.5106584028708637 0.6095902729059506 1.0 0.8244438213031886 8 Q15075,O00429 2 +Molecular function regulator 0.2281523577379799 0.5104593738652269 0.60972966963422 1.0 0.8244438213031886 318 Q96BK5,P43490,Q14997,Q6IN85,P62841,Q86YR5,Q13017,Q86XL3,P23381,P55145,Q96N67,Q9H2M9,Q9NR50,P54619,Q8IXB1,P30533,Q96CS3,Q99996,Q02818,O75569,Q12959,Q14185,P49354,Q9Y263,Q13177,Q13043,P07602,P26583,O43242,O95067,P62081,Q12846,Q13144,Q16543,Q92888,Q99543,Q9BXK5,Q9HAV7,Q9NPQ8,Q66K14,Q7KZI7,Q9NZM3,Q13576,O75695,P14174,Q96KC8,O14737,Q13464,Q8TDB6,Q96PU5,P36507,Q9UKS6,O00429,P61289,Q92974,Q06481,Q4KMP7,Q96EY1,P30044,P20338,P29692,O94887,Q86XI2,Q9NPI6,P80303,O15400,P09429,P55010,P51159,Q9UJ41,Q5JTV8,Q6NYC1,P60983,O43169,P63000,Q01968 76 +Structural constituent of ribosome 0.2721843852884487 0.5058922059242759 0.6129323241182254 1.0 0.8257108969982578 114 Q92665,Q8N5C6,P62841,Q9H2W6,Q9P015,P61254,Q16540,P62081,P46778,P50914,P82933,P08865,P25398,P84098,P62917,Q96A35,P62899,P46782,P61513,Q02543,P62753,P15880,Q7Z7H8,P27635,Q9Y3D3 25 +Rrna cytosine methyltransferase activity 0.4296934047594267 0.4994794673444671 0.6174416481352778 1.0 0.8274891217157071 3 Q96CB9 1 +C methyltransferase activity 0.4296934047594267 0.4994794673444671 0.6174416481352778 1.0 0.8274891217157071 3 Q96CB9 1 +Electron transfer activity 0.2790247830388063 0.4971756965207192 0.6190651582791644 1.0 0.8281535011146864 53 O43678,Q9P0J0,P51970,P14406,O75380,P14854,O43676,Q9UDW1,P00390,Q6FI81,O75306 11 +Aminoacyl trna editing activity 0.4176943582364705 0.4894545451304288 0.6245199277616802 1.0 0.8308244269888543 10 Q9BW92 1 +Hydrolase activity acting on glycosyl bonds 0.3047647886789027 0.489292792253087 0.6246344232105985 1.0 0.8308244269888543 33 P27695,P04062,Q9NUJ1,P33908 4 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3672151706980323 0.4859061152801015 0.6270337324190316 1.0 0.8323994316027842 16 P51530,P27695,Q9BQG2,Q96DE0 4 +Peptide lysine n acetyltransferase activity 0.3890543326748019 0.4818061158226863 0.62994368440684 1.0 0.8339530139813168 13 Q86UY6,Q09472,O60318,Q92993 4 +Mhc class i protein binding 0.4430687691965841 0.4808240285623753 0.6306415710458739 1.0 0.8339530139813168 7 P51572,P06576 2 +Gdp dissociation inhibitor activity 0.4410441326109456 0.4729199599038352 0.6362702841276497 1.0 0.8349082492616103 7 P55010 1 +Mrf binding 0.380113466706479 0.4651084666923216 0.6418537831000093 1.0 0.8380580994643136 2 Q92793 1 +Kinase activity 0.2514462735333095 0.4644951923438427 0.6422930031986409 1.0 0.8380580994643136 157 Q05682,P04183,P52789,Q13555,Q6P3W7,Q3LXA3,P54619,P35790,Q16512,P12532,Q9Y4A5,Q12959,Q99986,Q13177,Q13043,Q00534,O15111,P42345,P54646,P25440,P55263,Q9Y5P4,Q9NWH9,Q7KZI7,Q9Y3D8,P42356,Q13464,P78362,P24941,P12277,P36507,P48426,O14757,Q8WVC6,P17858,P17252,P67870,Q99570,Q9UBF8,Q15126,P27361,O60885 42 +Histone methyltransferase binding 0.447175919579128 0.4550935560002089 0.6490419338006477 1.0 0.8444325254576328 6 P83916 1 +Transferase activity transferring phosphorus containing groups 0.2377651127851331 0.4519022781568904 0.6513393831851362 1.0 0.8460137126611779 210 Q05682,P04183,P52789,Q9NR45,Q13555,Q6P3W7,Q3LXA3,Q9Y5P6,P54619,P35790,Q16512,P12532,Q9Y4A5,Q12959,Q99986,P28340,Q13177,Q13043,Q00534,O15111,P42345,P54646,Q13503,O14802,Q9NR33,P25440,P55263,Q9Y2S7,Q9Y5P4,Q7KZI7,Q9BWH6,Q8NFF5,Q2VPK5,P42356,Q9NWH9,Q13464,P78362,O00411,P24941,P36507,Q9Y3D8,P48426,P12277,O14757,P48651,Q8WVC6,P17858,P17252,P67870,Q99570,Q9UBF8,Q9UBZ9,Q15126,P27361,O60885 55 +Fatty acid binding 0.4069304171470416 0.4431417469080987 0.6576632108127043 1.0 0.8499986781258536 10 O15254,Q00169 2 +Ribonucleoprotein complex binding 0.2661851399789948 0.4403171483093784 0.6597074224196813 1.0 0.8510349987899843 91 Q7Z739,Q96D46,P09132,Q9UHB9,Q96EY7,P46199,P46379,P04844,Q9BXJ9,P13051,P42345,P57772,O14744,Q00839,Q99543,Q8IWS0,P41567,P08865,P49458,P41227,Q9UM00,O76094,P62136,Q92552,Q96A33 25 +Antiporter activity 0.4133126688830217 0.4369139733923719 0.6621737377001706 1.0 0.8523785783267142 9 Q9UBX3 1 +Oxidoreductase activity acting on nad p h 0.3009644083083895 0.4319253788490143 0.6657956487254413 1.0 0.8531284403269863 30 Q9P2T1,O43678,Q9P0J0,P51970,P16435,O75380,O95825,O43676,O75306 9 +Inositol trisphosphate phosphatase activity 0.4504906371210931 0.4247163126288249 0.671043490685562 1.0 0.8567843264112022 4 Q10713 1 +Oligosaccharyl transferase activity 0.4398824575721106 0.4077057206848721 0.6834897370383661 1.0 0.8661818851647846 5 P04844,Q9Y673 2 +Armadillo repeat domain binding 0.4047192353643787 0.405048103761657 0.6854421521635781 1.0 0.8661818851647846 3 Q13033,O43815 2 +Integrin binding 0.3449492519073543 0.4034901545907358 0.6865876761022394 1.0 0.8661818851647846 17 P46939,P35240,Q96AC1,P09429,Q03001,P35579,P17252,P12814 8 +Phosphatase activator activity 0.4328960448685126 0.4034421113847629 0.686623012619676 1.0 0.8661818851647846 6 P35269,Q6IN85,Q15257 3 +Protein kinase a regulatory subunit binding 0.3866146185344947 0.3914079707160444 0.6954957015624079 1.0 0.8712996603234006 11 P15311,Q99996 2 +Single stranded rna binding 0.2751362067286194 0.377689972693611 0.7056609176514668 1.0 0.8780703516644046 45 P05455,Q96EZ8,Q9Y606,O43347,Q6NYC1,P31483,O14979 7 +Cytokine receptor binding 0.3183077359180524 0.3759593891360301 0.7069470876237376 1.0 0.8780757117357393 22 P14174,Q9H2J4 2 +Minor groove of adenine thymine rich dna binding 0.4332043575500325 0.3675055466328013 0.7132419552527289 1.0 0.8830116309804537 4 P17096 1 +Lipid transporter activity 0.3219715890094412 0.3641659872976281 0.7157340639123801 1.0 0.8830116309804537 20 P28288,Q4KMQ2,Q9Y5P4,Q8NB49,Q96SU4,P08183,Q00169 7 +Laminin binding 0.4320410502054597 0.3637847886344882 0.716018722426383 1.0 0.8830116309804537 4 P08865,P17931 2 +Pdz domain binding 0.3426051897188233 0.3603962203882083 0.718550852692494 1.0 0.8847219016092162 16 P36507,Q8IUD2,Q9UQB8 3 +Nucleotide diphosphatase activity 0.3907054991316537 0.3557601259491359 0.7220202128130493 1.0 0.8879422724900158 3 Q9BQG2 1 +Intramolecular transferase activity 0.3698506874674631 0.3546621174386601 0.7228427342174595 1.0 0.8881565433882687 12 O95900,Q9Y606,Q96G03 3 +5 3 dna helicase activity 0.418097421947515 0.3525586344548929 0.7244193535182291 1.0 0.8892961597849227 6 P51530 1 +Exopeptidase activity 0.2853453941644954 0.344505359804644 0.7304662659164545 1.0 0.891924050183193 33 P36551,P53582,P42785,Q96DE0,Q9HB40 5 +Dna polymerase activity 0.3870946146671462 0.335116819675432 0.7375369654627169 1.0 0.8968190615225567 9 P28340,Q9UBZ9,P09884,Q9NR33,Q07864,Q9Y2S7 6 +Heparin binding 0.3567014781446238 0.3339691373034887 0.7384028477353606 1.0 0.8968190615225567 13 Q06481,O14737,P30533 3 +Transferase activity transferring one carbon groups 0.2573985211675064 0.3306081125638313 0.7409405175725188 1.0 0.898232852281106 70 Q05682,Q9BV86,Q86TU7,P04818,O60294,P34897,Q9H993,P21964,Q52LJ0,O14744,Q99873,Q8N4J0,Q14166,Q6FI81,Q96FX7,O60725 16 +S100 protein binding 0.390991661135053 0.3256583286135889 0.7446828758208945 1.0 0.9004550219546562 8 P15311 1 +Protein phosphatase 2a binding 0.3771308349572942 0.3236611712853372 0.7461945705455517 1.0 0.9012823074484316 10 Q9UPR3,Q86XL3,Q15257 3 +Protein serine threonine kinase activity 0.2541471984460172 0.3202190697477104 0.748802268131959 1.0 0.9012823074484316 85 Q13555,P54619,Q16512,Q9Y5S2,P49760,Q9NYV4,Q99986,Q13177,Q13043,Q00534,O15111,P46734,P42345,O75116,P54646,O95747,P25440,Q13557,Q7KZI7,Q13464,P78362,P24941,P36507,O14757,P17252,P67870,Q99570,Q13418,P11274,P27361,P53350,O60885 32 +Histone acetyltransferase binding 0.3988667566501001 0.3198261962449415 0.7491000880741092 1.0 0.9012823074484316 7 Q15650,O95905 2 +Phosphatidylinositol 3 5 bisphosphate binding 0.4124327555289839 0.3178087548515941 0.7506300093420879 1.0 0.9012823074484316 5 Q9Y4P8,Q9Y5X3,Q92538,Q9Y484 4 +Mitogen activated protein kinase binding 0.3880650791181112 0.3154577331675617 0.7524141379610199 1.0 0.901517096158643 8 Q99873,Q96JB5 2 +Protein phosphatase 1 binding 0.4106591329554361 0.312348539077776 0.754775655062957 1.0 0.901517096158643 5 Q9GZN8 1 +Protein kinase a binding 0.312219400215783 0.3117535718929337 0.7552278109286195 1.0 0.901517096158643 20 P15311,Q99996,P35241 3 +Protein phosphatase activator activity 0.4078061262143399 0.3036599371453594 0.7613869830464965 1.0 0.9046835791619257 5 Q6IN85 1 +Histone deacetylase activity h3 k14 specific 0.3724611708482556 0.2961649969772235 0.767104078690912 1.0 0.906807626813571 3 Q9UBN7,Q13547 2 +Protein methyltransferase activity 0.2848695718580981 0.2863691439755836 0.7745954050671244 1.0 0.9140359215693028 28 Q9BV86,Q86TU7,Q9H993,Q52LJ0,Q99873,Q14166,O60725 7 +Chaperone binding 0.2675733168355182 0.2836412402498292 0.7766853293372431 1.0 0.91409625773363 40 Q14108,O43615,Q9NQP4 3 +Dna dna annealing activity 0.4003226670759575 0.2814361478463453 0.7783758960715665 1.0 0.91409625773363 5 P46063 1 +Kinase regulator activity 0.2573686600588322 0.2806402043273178 0.7789863761260116 1.0 0.91409625773363 51 Q86XI2,Q13177,Q13043,P23381,P36507,O95067,P54619,Q16543,P60983,Q7KZI7 10 +Gamma tubulin binding 0.3951377342746297 0.2796318834459732 0.7797599430903428 1.0 0.91409625773363 6 Q96CW5,Q9BSJ2,Q16512 3 +Monocarboxylic acid binding 0.3062910404874059 0.2708768679008472 0.7864857368602021 1.0 0.9159164690862136 19 P07602 1 +Acetyltransferase activity 0.2765847556941633 0.2703566319698666 0.7868859008134843 1.0 0.9159164690862136 31 Q09472,Q9BXJ9,O60318,Q86UY6,Q92993,P41227 6 +Procollagen proline 4 dioxygenase activity 0.3602150537634251 0.2593333101355544 0.7953780805181618 1.0 0.92266551254012 3 P13674,O15460 2 +Peptidyl proline 4 dioxygenase activity 0.3602150537634251 0.2593333101355544 0.7953780805181618 1.0 0.92266551254012 3 P13674,O15460 2 +Proteasome binding 0.3454622513653728 0.2577612495245251 0.7965911724952477 1.0 0.9232909528921228 12 P46379,Q14997,P54725,Q92530,Q9Y5K5 5 +Nadplus binding 0.3770414573585631 0.2508209638905396 0.8019525327297743 1.0 0.9279349407430664 7 P00367 1 +Hydrolase activity hydrolyzing n glycosyl compounds 0.3557456039279023 0.2473250243699207 0.8046566935992512 1.0 0.9295417110890424 10 P27695 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.3915048582591041 0.2456181750238232 0.8059778185274462 1.0 0.9295417110890424 4 Q10713 1 +Transcription regulator inhibitor activity 0.3902001792650171 0.2422139111340761 0.8086144164128015 1.0 0.9295417110890424 4 Q00577,Q9NX58,Q9UER7 3 +Lrr domain binding 0.3180053747387206 0.239723484564658 0.8105446276689809 1.0 0.9295417110890424 2 Q6P1K2 1 +Leucine zipper domain binding 0.3180053747387206 0.239723484564658 0.8105446276689809 1.0 0.9295417110890424 2 Q6P1K2 1 +Intramolecular oxidoreductase activity transposing c c bonds 0.3644003622029669 0.2383359768479237 0.8116205196785784 1.0 0.9295417110890424 8 Q15125,P14174,Q13907 3 +Thiamine pyrophosphate binding 0.388394553348175 0.2375462265109217 0.8122330616747868 1.0 0.9295417110890424 4 A1L0T0 1 +Guanyl nucleotide exchange factor activity 0.2638874427349135 0.2367636872597707 0.8128401240034109 1.0 0.9295417110890424 38 Q14185,Q9Y2L1,O94887,Q96N67,Q9H2M9,P80303,Q9NR50,Q9UJ41,Q14344,Q92974,Q13144,Q92888,Q9H8V3,Q02818,Q9NPQ8,Q9NZM3,P29692 17 +Mrna binding 0.2247824134702262 0.2342012628153587 0.8148287346947012 1.0 0.9310386710022858 177 Q7Z739,P35580,P67809,Q8N5C6,P34897,Q8N684,P61247,Q9BPZ3,P62854,P00374,Q96EP5,Q14103,P57772,P61254,Q12972,Q8IY67,Q00839,P62081,Q96PU8,O75153,Q15366,Q9Y3Y2,Q96AE4,P61978,Q12849,O60506,Q09161,P12270,Q13310,P14866,P51116,Q9Y383,P46782,P05455,P04818,P31483,Q5VTR2,Q9NPI6,Q9H2U1,P15880,O43390,Q96DE0,Q8WVV9,Q01085,Q15637,P20042,P51608,Q15631 48 +Adp binding 0.294740856907251 0.2245717757742283 0.8223124237307617 1.0 0.9375207598452898 20 P35580,P48163,P00367,P54619,P25705,P35579 6 +Mannosyltransferase activity 0.3544543485669672 0.2089694786173596 0.8344720651271265 1.0 0.944035284247864 8 Q6ZXV5,Q9H6U8 2 +Nucleoside triphosphatase regulator activity 0.2450894214205341 0.2072222837134213 0.8358362651154116 1.0 0.944258587389719 88 Q86YR5,Q96N67,P49815,Q13017,Q9H2M9,Q9NR50,Q14344,Q02818,Q68EM7,Q14185,Q13144,Q92888,Q9NPQ8,Q9NZM3,Q66K14,Q13576,O75695,Q92974,O00429,Q4KMP7,Q96EY1,Q9H8V3,P29692,Q9Y2L1,O94887,P80303,P55010,O94813,Q9UJ41,P63167,Q15436,Q01968 32 +Pre mirna binding 0.369520417425965 0.1991743187370131 0.8421263876208691 1.0 0.9495581490046014 5 Q9H2U1,Q9HAV4,O75569 3 +Trna binding 0.2532731822779826 0.1961472700514641 0.8444948986485123 1.0 0.9501790675096222 43 Q2VPK5,P49591,Q9Y285,P05455,P49589,Q9Y606,P57772,O75127,Q92552,Q7Z7L1,Q12904 11 +5s rrna binding 0.3574325087550723 0.1958114595148559 0.8447577403114743 1.0 0.9501790675096222 7 P39023,Q9NZM5,P62913 3 +Protein disulfide reductase nad p activity 0.3624379313568684 0.1901797868138597 0.8491682498429682 1.0 0.9534068885078844 6 P00390 1 +Translation initiation factor binding 0.3081676066798124 0.1894751423931738 0.8497204357082162 1.0 0.9534068885078844 15 P20042,P55010 2 +Telomeric dna binding 0.2884995720750904 0.1885939079913321 0.8504111078515582 1.0 0.9534068885078844 19 Q9UPR3,Q14103,P15927,P27695 4 +Palmitoyltransferase activity 0.3621194674628623 0.1817476110932386 0.855780799917707 1.0 0.9572819330263824 5 P23786,O15269 2 +Peptidase activator activity involved in apoptotic process 0.329151732377522 0.1784314375977713 0.8583841618020751 1.0 0.9572819330263824 3 Q9BXK5,P63244 2 +Vitamin d receptor binding 0.3384228143354809 0.1775243643610698 0.8590965291671144 1.0 0.9572819330263824 9 Q9Y2X0,O75448 2 +Kinetochore binding 0.3276583034647405 0.1750158963411066 0.8610671428927386 1.0 0.9572819330263824 3 Q7Z460,Q96EA4 2 +Map kinase kinase activity 0.3365757046382412 0.1724725763543512 0.8630660191775856 1.0 0.9572819330263824 9 P36507,P27361 2 +Thiol oxidase activity 0.3603226770242003 0.1717138805073145 0.8636624728381646 1.0 0.9572819330263824 4 Q96HE7,Q6ZRP7,Q86YB8 3 +Nucleotidyltransferase activity 0.2426460145946607 0.1651436260806957 0.8688309357464021 1.0 0.9572819330263824 52 Q8NFF5,Q2VPK5,P28340,O00411,Q9NR45,Q13503,Q9UBZ9,Q9NR33,Q9Y2S7,Q9BWH6 10 +I smad binding 0.2899372947148307 0.1649992491900102 0.8689445730164169 1.0 0.9572819330263824 2 Q13485 1 +Actin binding 0.2446271373979749 0.1645739501640067 0.8692793363584295 1.0 0.9572819330263824 119 Q05682,P35580,P35221,P35240,Q5T1M5,Q03001,P04062,Q14651,Q8WXH0,P12814,P67936,P52907,P15311,P61160,P47755,Q00839,Q13576,Q86TU7,Q01082,A0MZ66,P06753,Q96AC1,Q92747,Q5SNT2,P35579,Q9NYL9,Q9P253,P35241,Q9Y4I1,Q9Y2J2,Q6WCQ1,P46939,Q9BR76,Q9P0K7,Q9UBN7,Q9UEY8,P59998,P38435,P60983,P26038,Q13813 41 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.3542793819687723 0.1643167917347677 0.8694817634653276 1.0 0.9572819330263824 5 Q10713 1 +Aldehyde lyase activity 0.3391691208619518 0.133753771233346 0.8935972838338382 1.0 0.9735585517892912 5 Q9H993 1 +O acyltransferase activity 0.312226689695782 0.1326767996669295 0.8944489918123284 1.0 0.9735585517892912 11 Q6UWP7,Q96N66 2 +Dynein intermediate chain binding 0.3241325575037855 0.1315750414201233 0.8953204279268725 1.0 0.9735585517892912 8 Q86Y56,Q96FJ2 2 +Extracellular matrix binding 0.3379253836332244 0.1314168792605466 0.8954455367427567 1.0 0.9735585517892912 5 P08865,P17931 2 +7sk snrna binding 0.3357249626308023 0.1310280290621364 0.8957531345627059 1.0 0.9735585517892912 6 P50750,Q9NR30,Q7L2J0,Q9NY93,Q4G0J3 5 +Sumo ligase activity 0.3046594982078741 0.1280555674474584 0.8981049985096052 1.0 0.9749634294438662 3 O75925,Q8N2W9 2 +E box binding 0.334534821231231 0.1251843734914983 0.9003775880697638 1.0 0.9758839364363736 5 O14744 1 +Phosphotransferase activity phosphate group as acceptor 0.2920265617624512 0.1222490354019107 0.9027017930146556 1.0 0.9770669501840628 14 Q15126 1 +Ubiquitin like modifier activating enzyme activity 0.3197726592880621 0.122004512545887 0.9028954444766596 1.0 0.9770669501840628 8 Q13564,P22314,Q9UBT2,A0AVT1,Q8TBC4,O95352,Q9GZZ9 7 +Polyubiquitin modification dependent protein binding 0.2716162892964699 0.1203444189583692 0.9042103185343696 1.0 0.9771450153471692 19 P46379,P35573,Q6GQQ9,P55036,Q8TAT6,P54725 6 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.3320401342980877 0.1186514579373074 0.905551495727026 1.0 0.977624546214362 4 P04844 1 +Ferrous iron binding 0.3253389196431915 0.1080467282162666 0.913958625387647 1.0 0.9812878658158908 4 Q9NWT6 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.3175231195166053 0.1062802691718696 0.915359985836628 1.0 0.9820228508975573 7 Q10713 1 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.3139253549599128 0.0997329564422365 0.9205563355152888 1.0 0.9835236765305542 7 Q9Y5K8 1 +Atpase coupled ion transmembrane transporter activity 0.3139253549599128 0.0997329564422365 0.9205563355152888 1.0 0.9835236765305542 7 Q9Y5K8 1 +Enoyl coa hydratase activity 0.3132364759192591 0.0985079845652532 0.9215289320322112 1.0 0.9835236765305542 7 Q08426 1 +Anaphase promoting complex binding 0.2865190114944787 0.0984272477797901 0.9215930391251812 1.0 0.9835236765305542 3 Q16763 1 +Ubiquitin protein transferase regulator activity 0.2968726658137431 0.0949698026104731 0.9243388125075744 1.0 0.9847932914089756 11 P62841 1 +Beta tubulin binding 0.2673474477807835 0.0904965747487304 0.9278926157410377 1.0 0.986200840624687 18 O75381,O14737 2 +Uridylyltransferase activity 0.2786738351254364 0.0875713069237188 0.9302174082995656 1.0 0.9878904421628488 3 Q16222,Q16851 2 +Endopeptidase activity 0.23145371008732 0.0866817326898978 0.930924496957838 1.0 0.9878904421628488 67 P67812,Q13043,Q8TCT9,P22695,Q96RU2,Q96TA2,P49721,Q4J6C6,Q10713 9 +Ubiquitin like protein conjugating enzyme binding 0.286662943898702 0.0808907916394962 0.9355288031746392 1.0 0.9912408819406464 12 Q9BTE7,Q96GG9 2 +Nucleoside binding 0.2958756724447024 0.0681086927889237 0.9456991105826956 1.0 0.9973885923774388 5 O43707,P30876,P00491,Q9H9Y6 4 +Map kinase activity 0.2884040645546836 0.059905720640891 0.9522307236675992 1.0 1.0 5 O43318,P28482,P27361,Q13164 4 +Syntaxin 1 binding 0.2863120143454777 0.0577616860522723 0.9539384572995028 1.0 1.0 5 O14795,P46459,O75150,O00186 4 +Long chain fatty acid transporter activity 0.2790558709291856 0.0541599031518503 0.9568077664200088 1.0 1.0 4 O14975,Q01469,P28288 3 +Protein kinase activity 0.2333192360955864 0.0534874082384715 0.957343563058516 1.0 1.0 100 Q05682,P53350,Q13555,Q6P3W7,P54619,Q16512,Q9Y5S2,P49760,Q9NYV4,Q99986,Q13177,Q13043,Q00534,O15111,P46734,P42345,O75116,P54646,O95747,P25440,Q13557,Q9NWH9,Q7KZI7,Q13464,P78362,P24941,P36507,O14757,P17252,P67870,Q99570,Q13418,P11274,P27361,Q13308,O60885 36 +Annealing activity 0.2775326208099275 0.0501791036764491 0.9599796634233366 1.0 1.0 9 P46063 1 +Transferase activity transferring alkyl or aryl other than methyl groups 0.2395032409615833 0.0462758566258893 0.9630903823104984 1.0 1.0 27 P49354,P37268,Q9NR45,Q7Z6K3,O43708,P19623,Q9UJK0 7 +Peptidase activator activity 0.2695028713383275 0.042156995995576 0.9663735442853688 1.0 1.0 11 P61289,Q14997 2 +Catalytic activity acting on a trna 0.2242500883690684 0.0364555110336266 0.9709191521612828 1.0 1.0 64 Q9Y285,P49589,P23381,Q5VV42,O75879,Q96FX7,Q9BTE6,Q9HA77,A2RTX5,Q5T160,Q9BXR0,P54136,P49591,P41250,P49590,O15091,Q9BW92,Q9Y3E5,O60294,Q9Y606,P47897 21 +Enzyme activator activity 0.2326413137508119 0.0361704418922685 0.9711464545136426 1.0 1.0 120 Q14997,Q6IN85,Q13017,Q9Y263,Q13043,P07602,Q12846,Q7KZI7,Q66K14,Q13576,O75695,O14737,Q8TDB6,P36507,O00429,Q4KMP7,Q9NPI6,O43169,Q01968 19 +Rna stem loop binding 0.2604006230851095 0.0304936288716666 0.975673374443881 1.0 1.0 7 Q96EP5,P35580 2 +Intramolecular transferase activity phosphotransferases 0.249551703526594 0.0298738979110914 0.9761676230050405 1.0 1.0 5 Q6PCE3,P18669,Q96G03,O95394 4 +Nuclear receptor coactivator activity 0.2403417588535902 0.0283411060275537 0.977390095886472 1.0 1.0 23 Q15648,O75448,Q99816,Q16512,P17096 5 +Sumo transferase activity 0.2387925881649667 0.0247243254441195 0.9802748521107434 1.0 1.0 5 P49792,O75925,P14373,Q8N2W9 4 +Ubiquitination like modification dependent protein binding 0.2150514044972155 0.0169701975951825 0.9864603912214028 1.0 1.0 5 Q99543 1 +Carbohydrate kinase activity 0.2443720241701279 0.0163702354205864 0.98693902526051 1.0 1.0 8 P17858,P52789 2 +Calmodulin binding 0.2241343510014842 0.0125669147379719 0.9899733166689222 1.0 1.0 39 Q05682,Q13576,P35580,Q9Y4I1,O14795,Q01082,Q99797,Q15075,Q5T4S7,Q13555,Q9UEY8,P35579,Q13813 13 +Insulin receptor binding 0.2179372197309484 0.0115057573861901 0.9908199363682192 1.0 1.0 6 O14654,Q8WWQ0,O60749,Q13596,Q06124 5 +Phosphatase binding 0.2179311735447666 0.0059198102394054 0.9952767023944392 1.0 1.0 55 Q9Y496,Q9UJX5,P49815,Q9GZN8,Q86XL3,P15927,Q9NX63,Q9UPR3,O43815,P27361,P55199,P62136,Q15257,Q9UJX4,Q9NWH9,Q12959 16 +Translation factor activity rna binding 0.2176703711854942 3.3937993204651075e-05 0.9999729213992026 1.0 1.0 59 P46199,Q9ULC4,P41567,Q9NR50,Q7Z478,P57772,P55010,Q13144,P20042,P29692 10 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f4d912b3c8f1a846b171f1eca55b2d95a1445cee --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "Butyrate coa ligase activity", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n acetyltransferase activity acting on acetyl phosphate as donor", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i core binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Vasopressin receptor activity", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf54", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA5", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NF2", "NFAT5", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REL", "RELA", "REPS1", "RER1", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTKN", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPCS2", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM192", "TMEM201", "TMEM43", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "WARS", "WARS2", "WASF2", "WASHC2A", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["AARSD1", "ABCB1", "ABCB10", "ABCD3", "ABHD10", "ACAD11", "ACOX3", "ACSF2", "ACTN1", "ACTN4", "ACTR2", "ADD3", "ADK", "AGK", "AGL", "AIMP1", "AIP", "AK6", "AKAP9", "ALDH3A2", "ALG11", "ALG5", "ALG9", "AMOT", "ANAPC4", "ANAPC5", "ANKFY1", "ANKLE2", "ANO6", "APEX1", "APLP2", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARMT1", "ARPC1A", "ARPC4", "ASNA1", "ATG7", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP5A1", "ATP5B", "ATP5F1", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAG6", "BAIAP2", "BCAP31", "BCL10", "BCL2L13", "BCR", "BLM", "BLVRA", "BLVRB", "BRD2", "BRD4", "BSG", "BTAF1", "C20orf27", "CACYBP", "CADM1", "CALD1", "CAMK2D", "CAMK2G", "CAPZA1", "CAPZA2", "CARNMT1", "CARS", "CARS2", "CASP8", "CBX1", "CCDC47", "CCNB2", "CCNK", "CDC37", "CDC42BPB", "CDC6", "CDK12", "CDK2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CERS2", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHEK1", "CHKA", "CHMP6", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLIP1", "CLK2", "CLUH", "COL4A3BP", "COMT", "CORO1B", "COX6B1", "COX7A2", "CPOX", "CPSF7", "CPT2", "CRABP2", "CREBBP", "CRTAP", "CRYZL1", "CSNK2B", "CSRP2", "CTNNA1", "CTU2", "CUL5", "CYB5B", "CYP51A1", "DAGLB", "DAXX", "DAZAP1", "DCAKD", "DCP1A", "DCTN2", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DDX1", "DDX21", "DDX3X", "DDX56", "DHCR24", "DHFR", "DHRS7B", "DHX29", "DHX36", "DIS3", "DLG1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DOHH", "DRG1", "DST", "DTX3L", "DYNC1I2", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECD", "ECE1", "ECT2", "EEA1", "EEF1D", "EEFSEC", "EHHADH", "EIF1", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3E", "EIF5", "ELL", "EMC2", "EMC3", "EP300", "EPB41L3", "ERC1", "ERCC2", "ERCC3", "ERO1A", "ERO1B", "EXOG", "EXOSC1", "EZR", "FABP5", "FAF2", "FAM98B", "FARP2", "FARSA", "FDFT1", "FERMT2", "FKBP15", "FLAD1", "FNTA", "FUBP1", "FXR2", "GALNT1", "GARS", "GATB", "GBA", "GBF1", "GDE1", "GGCX", "GLRX", "GLUD1", "GMFB", "GMPPB", "GMPR2", "GNA13", "GOLGA2", "GOLGA5", "GPSM1", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTZ1", "GTF2B", "GTF2F1", "GTF2H4", "GYG1", "H2AFX", "HARS2", "HDAC1", "HDAC6", "HIF1AN", "HK2", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HNRNPD", "HNRNPDL", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPR", "HNRNPU", "HSD17B12", "HSD17B4", "ICMT", "IDE", "IDI1", "ILK", "ILVBL", "INTS6", "IQGAP2", "IRS4", "ITSN2", "JMJD6", "KAT5", "KAT7", "KCTD10", "KCTD5", "KDELR1", "KDM3A", "KIAA0391", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIFC1", "KLC2", "KTN1", "LANCL2", "LARP7", "LCLAT1", "LCMT2", "LGALS3", "LIG1", "LLGL1", "LMNB1", "LPCAT1", "LRPAP1", "LUC7L2", "LYAR", "MACF1", "MAD2L1", "MAN1A1", "MANF", "MAP2K2", "MAP2K3", "MAP3K7", "MAPK1", "MAPK3", "MAPK7", "MARK2", "MBD1", "MBOAT7", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCRS1", "MCTS1", "ME1", "MECP2", "MED1", "MED16", "MED21", "MED24", "MEPCE", "METAP1", "METAP2", "MID1", "MIF", "MIPEP", "MORF4L1", "MPG", "MPRIP", "MRE11", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTAP", "MTCH1", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MYH10", "MYH9", "MYO1D", "MYO5A", "NAA10", "NAA15", "NAA40", "NAE1", "NAMPT", "NANS", "NCAPG2", "NCBP1", "NDC1", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "NES", "NF2", "NMD3", "NOP53", "NPLOC4", "NSF", "NSUN4", "NT5C3B", "NT5DC1", "NTMT1", "NUCB1", "NUCB2", "NUDT12", "NUDT16", "NUMA1", "NUP93", "OCRL", "OPA1", "ORC3", "ORC5", "OSBPL9", "OTUD7B", "OXSR1", "P3H1", "P4HA1", "P4HA2", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAIP2", "PAK2", "PALD1", "PARP1", "PCBP2", "PCYOX1", "PDCD5", "PDCL3", "PEX14", "PEX19", "PEX5", "PFDN4", "PFKL", "PGAM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHB2", "PHF6", "PHIP", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PIGK", "PIK3R4", "PINX1", "PIP4K2A", "PIR", "PITPNA", "PKN1", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLK1", "PLOD3", "PLS1", "PMF1", "PMPCA", "PMVK", "PNP", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE4", "POLR1B", "POLR2B", "POLR3A", "POLRMT", "PON2", "POR", "PPIG", "PPP1CA", "PPP1R8", "PPP4R3A", "PPT1", "PRC1", "PRCP", "PRDX5", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPSAP1", "PRPSAP2", "PRTFDC1", "PSAP", "PSMB2", "PSMD11", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSMF1", "PTAR1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTK7", "PTPA", "PTPN11", "PTRH2", "PURA", "PUS1", "PYCR2", "QARS", "QKI", "QSOX2", "QTRT1", "RAB27A", "RAB3GAP2", "RAB4A", "RABGEF1", "RAC1", "RACK1", "RAD23A", "RAD50", "RAD54L2", "RAI14", "RANBP2", "RARS", "RARS2", "RAVER1", "RDX", "RECQL", "REV1", "RFC1", "RIC8A", "RIOX2", "RIPK1", "RNF20", "RNF40", "ROCK1", "ROCK2", "RP2", "RPA2", "RPA3", "RPAP1", "RPL10", "RPL11", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL26", "RPL3", "RPL31", "RPL37A", "RPL8", "RPN2", "RPS12", "RPS15", "RPS2", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "RRN3", "SAMHD1", "SARS", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SCYL2", "SEC11A", "SEC13", "SEC23A", "SEH1L", "SETD3", "SF1", "SFPQ", "SFXN4", "SHMT2", "SHTN1", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC27A2", "SLFN11", "SLIT2", "SLTM", "SMAD4", "SMARCA1", "SMARCA4", "SMARCE1", "SMC3", "SMG5", "SNU13", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SPDL1", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQOR", "SRBD1", "SRM", "SRP19", "SRP68", "SRP72", "SRP9", "SRPK2", "SSB", "SSBP1", "STAMBP", "STAT3", "STK4", "STMN1", "STOML2", "STRN", "STRN3", "STX4", "STX7", "STXBP3", "SUPV3L1", "SYNCRIP", "SYNE2", "TARS2", "TARSL2", "TBC1D10B", "TBC1D9B", "TFAM", "TFAP4", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM44", "TIMM8B", "TK1", "TKFC", "TMCO1", "TMEM192", "TMEM201", "TMOD3", "TMTC3", "TMX1", "TOMM22", "TOR1AIP1", "TPM3", "TPM4", "TPP1", "TPR", "TRAF2", "TRAP1", "TRIM27", "TRIP4", "TRMT61A", "TRRAP", "TRUB2", "TSC2", "TSG101", "TSN", "TSR3", "TTF2", "TTLL12", "TUBB4A", "TUBG1", "TUBGCP2", "TUBGCP3", "TWNK", "TYMS", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2M", "UBE2S", "UBR4", "UCHL5", "UFSP2", "UGP2", "UNC13B", "UNG", "UQCR10", "UQCRC2", "USP28", "UTRN", "VBP1", "VDAC1", "VDAC2", "VIM", "VPS18", "VRK1", "WARS", "WDR45", "WIPI2", "XPO5", "YBX1", "YME1L1", "YTHDF3", "YWHAH", "YY1", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_hp/advanced/idx2term.json b/msigdb_hp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b0f4433a93b12745faac3ca4b25f55e060bfff19 --- /dev/null +++ b/msigdb_hp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Abnormal pulmonary interstitial morphology", "1": "Biliary tract abnormality", "2": "Abnormal muscle fiber morphology", "3": "Abnormal biliary tract morphology", "4": "Variable expressivity", "5": "Wide anterior fontanel", "6": "Increased bone mineral density", "7": "Poor suck", "8": "Phenotypic variability", "9": "Abnormality of pancreas physiology"} \ No newline at end of file diff --git a/msigdb_hp/advanced/plot_0.png b/msigdb_hp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..aefb77ca54d792de6b66c775f6490e92c3feb9c1 --- /dev/null +++ b/msigdb_hp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2a65245bb2b3da27f9c57a88c658ad7ad5707a02913c17e7261d6b50a8cbec3 +size 210695 diff --git a/msigdb_hp/advanced/plot_1.png b/msigdb_hp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..16942babb71da1fd9959cf3613f2500cf3e19ad2 --- /dev/null +++ b/msigdb_hp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c533870c2b7fbc1a5d191b1db0a5a47b99b05450424117baa15935ccfe871f5 +size 205786 diff --git a/msigdb_hp/advanced/plot_2.png b/msigdb_hp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a9cf7b6eb9c4cd56c6a593e87e783a4efe178294 --- /dev/null +++ b/msigdb_hp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37992622cd5022d1e30c22796e8ded5d45d92f44584727d718300630d77c483f +size 215202 diff --git a/msigdb_hp/advanced/plot_3.png b/msigdb_hp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f6612c036f20fd78cf85ad0f060f881540b4d608 --- /dev/null +++ b/msigdb_hp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8eadf3ec680284cee8dd26e466911a4f9ab9a9a5c95a69437302b212d8e962ea +size 205833 diff --git a/msigdb_hp/advanced/plot_4.png b/msigdb_hp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..67664fd3ea7f8afade4ea1c4e832ff8c01d0259e --- /dev/null +++ b/msigdb_hp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f86c8945c1e0633de170faff0b9a19c6c7b47f9bf0947203a89b0033bed39aa3 +size 213732 diff --git a/msigdb_hp/advanced/plot_5.png b/msigdb_hp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..56762eb19148eaf287f734fe81595b87cdb6ed6f --- /dev/null +++ b/msigdb_hp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ced3cf2cfade832582e2253ad5efd6e2c470ec95885e444677d6f3e1bb3d52c +size 202324 diff --git a/msigdb_hp/advanced/plot_6.png b/msigdb_hp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2c63a1f6db9493a81f2209b2914421ba797718b5 --- /dev/null +++ b/msigdb_hp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83ff4180955f4771f3ea2e07dbeedb650531b234340eeef16c0c1f64ec4f26cf +size 208305 diff --git a/msigdb_hp/advanced/plot_7.png b/msigdb_hp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..12888a8cc78258776c848f019f8bbfbba434c3b1 --- /dev/null +++ b/msigdb_hp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d283c33b147beb6e896c64dd424cb976e4ccd004aab01e5cc4d8c0148ec9e882 +size 203933 diff --git a/msigdb_hp/advanced/plot_8.png b/msigdb_hp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..2abe2bbf9109faf9d05775521db1b4fb37562106 --- /dev/null +++ b/msigdb_hp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:557e9e5ec4236a46753c282620ec096ecbcea466e88b7cc0d25702f586830864 +size 218955 diff --git a/msigdb_hp/advanced/plot_9.png b/msigdb_hp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..5e964d19549fb7f0a33a7b4a81ecea0c695aa036 --- /dev/null +++ b/msigdb_hp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ecf0d35012e80c1b521d571a492c20543d77883c08d589378bec675fc5f0da21 +size 210180 diff --git a/msigdb_hp/basic/idx2term.json b/msigdb_hp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a230ef7812736c912b863deecb54cf1f119627d0 --- /dev/null +++ b/msigdb_hp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Abnormal pulmonary interstitial morphology", "1": "Biliary tract abnormality", "2": "Abnormal muscle fiber morphology", "3": "Abnormal biliary tract morphology", "4": "Variable expressivity", "5": "Wide anterior fontanel", "6": "Increased bone mineral density", "7": "Poor suck", "8": "Phenotypic variability", "9": "Abnormality of pancreas physiology", "10": "Osteopenia", "11": "Abnormal activity of mitochondrial respiratory chain", "12": "Abnormality of the anterior fontanelle", "13": "Thin skin", "14": "Prenatal movement abnormality", "15": "Abnormality of humoral immunity", "16": "Pathologic fracture", "17": "Bruising susceptibility", "18": "Decreased activity of mitochondrial complex i", "19": "Ophthalmoparesis", "20": "Abnormality of fontanelles", "21": "Abnormality of the biliary system", "22": "Abnormal saccadic eye movements", "23": "Abnormal leukocyte physiology", "24": "Delayed cranial suture closure", "25": "Adipose tissue loss", "26": "Aplasia hypoplasia of the skin", "27": "Abnormal cellular phenotype", "28": "Open mouth", "29": "Malabsorption", "30": "Progeroid facial appearance", "31": "Microretrognathia", "32": "Functional abnormality of male internal genitalia", "33": "Congenital onset", "34": "Limb girdle muscle weakness", "35": "Abdominal pain", "36": "Death in infancy", "37": "Dental crowding", "38": "Prominent superficial blood vessels", "39": "Emg myopathic abnormalities", "40": "Increased susceptibility to fractures", "41": "Patent foramen ovale", "42": "Low set posteriorly rotated ears", "43": "Horizontal nystagmus", "44": "Decreased adipose tissue", "45": "Opisthotonus", "46": "Abnormal macular morphology", "47": "Enlarged thorax", "48": "Myoclonus", "49": "Subcutaneous hemorrhage"} \ No newline at end of file diff --git a/msigdb_hp/basic/plot_0.png b/msigdb_hp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bb6ca7981d8385e8c963f42e03c2beadaf6073c7 --- /dev/null +++ b/msigdb_hp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05833f8f72363b5236711a9e6c32cb04012755af2bbb305fe066aa2d6efcbd3b +size 144890 diff --git a/msigdb_hp/basic/plot_1.png b/msigdb_hp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7169ff17486e334288526777596baf85ad7101c6 --- /dev/null +++ b/msigdb_hp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ac09fc21e45664d7cc51a6a2ac2fbc194969c04191626ddb12dd193a107323f +size 139487 diff --git a/msigdb_hp/basic/plot_10.png b/msigdb_hp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..3121962c08f7e9c2a76393088bec9e0c9387ea70 --- /dev/null +++ b/msigdb_hp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65c1f2494362745b5372b05a9bb2d6981abc8594db1156b6964a9e882d8ed4b9 +size 138989 diff --git a/msigdb_hp/basic/plot_11.png b/msigdb_hp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..6e16d3cd8a8c347376b262671529c5a3497cefb8 --- /dev/null +++ b/msigdb_hp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:920d419deb9ca43f865e830780e656077443faec85db7df04c3b60f819b25994 +size 148267 diff --git a/msigdb_hp/basic/plot_12.png b/msigdb_hp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..cfb183408fb0d6604527aaf4934ee1c3daf5003c --- /dev/null +++ b/msigdb_hp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1254c657aea8e8ba18675d980b94390a5fe07794c7c26155df6835ddefe4ee7f +size 147418 diff --git a/msigdb_hp/basic/plot_13.png b/msigdb_hp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..6cd8dc9d053cb8dc831fffa7bc6980823ec2cfcd --- /dev/null +++ b/msigdb_hp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df4f97becdf05176f285e6882a85409b5e897278bff51e6c80abac25b3b8a6a3 +size 128441 diff --git a/msigdb_hp/basic/plot_14.png b/msigdb_hp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..4bf4a54671b22d906ca6aaaf08b0bf5fa4ed929e --- /dev/null +++ b/msigdb_hp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1b9d1a6f2f7d9fe0db71dfb9f7d511e10fff8d1523857d27d55f9466778b3f9 +size 143780 diff --git a/msigdb_hp/basic/plot_15.png b/msigdb_hp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..87636ed7371cea7164668399215a31f4b2869836 --- /dev/null +++ b/msigdb_hp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95025647067c770ce7bf044c6da2c324fd37bd9009e133772db0e2d7facd62b0 +size 141888 diff --git a/msigdb_hp/basic/plot_16.png b/msigdb_hp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..34eb7c3d2c5dff2c4aecac6cdf634dd548cc2bb9 --- /dev/null +++ b/msigdb_hp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d5e6caf4575dfc97b44f860f1f271ba6397a01f0d8e7edd2097ec22e31c0676 +size 127404 diff --git a/msigdb_hp/basic/plot_17.png b/msigdb_hp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..5a9ffa9d45b6151b6f7c92167c124c139a7e0c49 --- /dev/null +++ b/msigdb_hp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bd50a503f36f94673d3139005d18e0e615991bd48d9bed0e442e2902bb351f2 +size 134293 diff --git a/msigdb_hp/basic/plot_18.png b/msigdb_hp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..5d333ae1550f9d648f9e62d3c290a652e6f42702 --- /dev/null +++ b/msigdb_hp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c50183ae6a99f8f4994b3552bbdfe4dafc02b3241626fe7e582d8bb8ca29ccd +size 144122 diff --git a/msigdb_hp/basic/plot_19.png b/msigdb_hp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..cb7cf9fe35730cc44218428a1a6e1113b47856a6 --- /dev/null +++ b/msigdb_hp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae27e2853e6cf64cacf058280b8491f9144021cc53e050b9e4d2c4469cb10443 +size 140974 diff --git a/msigdb_hp/basic/plot_2.png b/msigdb_hp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3b310374bf6f8684f16cc706c76597bf2a75a214 --- /dev/null +++ b/msigdb_hp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48c21dfcdedaa7cf3ae118749ef17a870d32281559ded5ede0b43934c8ca0344 +size 154550 diff --git a/msigdb_hp/basic/plot_20.png b/msigdb_hp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..f465efb8c5f5a8b27caa251f0ca9ba0946e643a3 --- /dev/null +++ b/msigdb_hp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99717e51875bc0028f1fc603621b0816db2dbefb62bf66285fbf51fe0aeaf9c6 +size 145965 diff --git a/msigdb_hp/basic/plot_21.png b/msigdb_hp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..8ea10046d59fcdeac78517ad5df3e759750e78c3 --- /dev/null +++ b/msigdb_hp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe1780fbc72fcb78484fff84820823dc7cb096f53d9188ef4b05a26e38b23603 +size 144275 diff --git a/msigdb_hp/basic/plot_22.png b/msigdb_hp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..ffc24fc797ec25af09bda0aaa5955279ae9e5d87 --- /dev/null +++ b/msigdb_hp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:036850e28756d23c52202122844018f031cd7e5b2ac072fba453c9f2dd0b6581 +size 146583 diff --git a/msigdb_hp/basic/plot_23.png b/msigdb_hp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..7bffb0d9699f19b5ca1c07235f64c24abb290b78 --- /dev/null +++ b/msigdb_hp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:282e50e1fffef207c24147977398a705fa42978abedeb01ddb5b2bdb2eadfef3 +size 146786 diff --git a/msigdb_hp/basic/plot_24.png b/msigdb_hp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..816e873fe58c199b3b9d734204e089182dbf7c27 --- /dev/null +++ b/msigdb_hp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6dd51aada31ab8539d473e3cf0e67577f3ff188a816914e9ff68f4f73668ddd +size 147237 diff --git a/msigdb_hp/basic/plot_25.png b/msigdb_hp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..215720eb28a10955f3c2e13b497bc4c0ba0a8586 --- /dev/null +++ b/msigdb_hp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b43c87df073ab56defa89db793b79759a492a51d2fe27773db8d099e0c1f08d +size 132383 diff --git a/msigdb_hp/basic/plot_26.png b/msigdb_hp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..0eb83c35b523628534d164ef39e16569592974bc --- /dev/null +++ b/msigdb_hp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d9e566c93f54a5d186ba9d03d05c90b5ca1c578a38c198184ed471f42c66d6d +size 142822 diff --git a/msigdb_hp/basic/plot_27.png b/msigdb_hp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..38d482611b7a5766fd859ff87a1023d59cb85cdc --- /dev/null +++ b/msigdb_hp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7034806439d8521d145c10a3f8f2a10b0f71dc3765d3e6983ef3bb0c31a04bad +size 137887 diff --git a/msigdb_hp/basic/plot_28.png b/msigdb_hp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..2afd915b9074bfcaf1590e40b6c2b66291302e2f --- /dev/null +++ b/msigdb_hp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6df59e5c283b54012f9a7b13b969f47344fb5575bfad266baf0d65e1b9b2a5eb +size 135645 diff --git a/msigdb_hp/basic/plot_29.png b/msigdb_hp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..e827ac6875241a1ce3d7d3c272ceaadbb112326f --- /dev/null +++ b/msigdb_hp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:604d903dbdf671d581ceb9b9058cbcfb697d8674669ff00f1af72470a75ff799 +size 137578 diff --git a/msigdb_hp/basic/plot_3.png b/msigdb_hp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c00035fe53d9e5fa107ef48e23882f239a2819b8 --- /dev/null +++ b/msigdb_hp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f67d71c2f265cdb01ad194aa56d9c1e450179f726206b066f347a7816a5ebf26 +size 141965 diff --git a/msigdb_hp/basic/plot_30.png b/msigdb_hp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..c87ca07b79067edbb1c26b2e77f115b84c217275 --- /dev/null +++ b/msigdb_hp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a48b1988ebc6fb42a2c0b79ab2023fa1ba86d5cd3c3524ed9272f770374e0cc +size 136423 diff --git a/msigdb_hp/basic/plot_31.png b/msigdb_hp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..881179dd74331b7d9094797c2128e68cedb0d778 --- /dev/null +++ b/msigdb_hp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f1307636a73d616fba429982112c69c967bb5881696ff485c59a5eae512bc34 +size 133657 diff --git a/msigdb_hp/basic/plot_32.png b/msigdb_hp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..ba82eea5e050d9bfe3f3f1ade16218d2ae15b255 --- /dev/null +++ b/msigdb_hp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e7e1e2adc504119b225261fdbc77c155431f90db64a6c8cd3b3b517d861ae3a +size 145576 diff --git a/msigdb_hp/basic/plot_33.png b/msigdb_hp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..bfcd9d8fb0de7886f8cc9e38952c91f5aa3c031a --- /dev/null +++ b/msigdb_hp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4771f8ae7afb2f34f8259739034d9884cc4f549b34aa0770cf924d7e950f1e9 +size 139817 diff --git a/msigdb_hp/basic/plot_34.png b/msigdb_hp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..7fa0b305bd000559f0d2651323f5e20f6af8b060 --- /dev/null +++ b/msigdb_hp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97e830e57faf871db3dcf363380581759848c2bcd6d6a84583f9a33ea1a19b4a +size 137583 diff --git a/msigdb_hp/basic/plot_35.png b/msigdb_hp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..fe16576aad3ef05db4d76bc2079cc57951db02a7 --- /dev/null +++ b/msigdb_hp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ed39582fc5ead8133c4384e2a6ac2cfa7d37d8be6e07d7d6751436b9e63361f +size 136668 diff --git a/msigdb_hp/basic/plot_36.png b/msigdb_hp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..52eeba91a09586cbdcdcc3c84d6a0008a4452a4a --- /dev/null +++ b/msigdb_hp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:038433293e90fed206a8303f12d30a8ac5dbce9c2456b9f4aec5576794261c29 +size 138146 diff --git a/msigdb_hp/basic/plot_37.png b/msigdb_hp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..ceae2b4764d8ae1913d902b7faaf6be3b4ff5212 --- /dev/null +++ b/msigdb_hp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5a92b2b63459cf7c4bbbd0fa0ef3fd2fc63ac3bb52f65bcdcc761cbf22f5838 +size 138207 diff --git a/msigdb_hp/basic/plot_38.png b/msigdb_hp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..80b5fc27d11b6b3af9a22503103d6e393b3df65a --- /dev/null +++ b/msigdb_hp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b528e85d84f9e4035babaa298c99beb682e91544b0a842d1f0cafee57653c1e3 +size 140705 diff --git a/msigdb_hp/basic/plot_39.png b/msigdb_hp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..630ab65e4ab3f81a5a7064d6ea82c3189e0f43ec --- /dev/null +++ b/msigdb_hp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00cb8d3797af2c3e88664f2ff4a4012ad28d38cb5c952c5119f80949e3ce2e32 +size 145549 diff --git a/msigdb_hp/basic/plot_4.png b/msigdb_hp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..f793625c26a1ac6237d87c7e38b53518d670eb6f --- /dev/null +++ b/msigdb_hp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcc1d102f3cb25aa0db50c38a27fabf5e075e35d47ad6aed1aff1f184816f992 +size 145144 diff --git a/msigdb_hp/basic/plot_40.png b/msigdb_hp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..55f0f85daedec0c07325abfe92890d3dd4d3bc82 --- /dev/null +++ b/msigdb_hp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cba9c322e6ea60dc30ddb4338500d58a2b9df55c87abbd897b80f8a618f13bbd +size 147710 diff --git a/msigdb_hp/basic/plot_41.png b/msigdb_hp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..66f9f2f9363d97df2df97e472588c943d8e116e7 --- /dev/null +++ b/msigdb_hp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c8b2f16710471e6992f28390a89dab5effcc826f4b93b7ea3e2a0086b04e869 +size 140953 diff --git a/msigdb_hp/basic/plot_42.png b/msigdb_hp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..c5fdae85c0fe41a7544b93f0a65eb4a11ac3bcdc --- /dev/null +++ b/msigdb_hp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:336fd3c37d635a14c4e84da858c34a7dfc03b5138b218cb15827f0f04a42a2b8 +size 148237 diff --git a/msigdb_hp/basic/plot_43.png b/msigdb_hp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..3cc3c4c1256b0367b5d25cd48e15f545dbac6521 --- /dev/null +++ b/msigdb_hp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd373f926ca1a189ba97f168f11158c12982cc4728e1d482b204acf9656a21c8 +size 133669 diff --git a/msigdb_hp/basic/plot_44.png b/msigdb_hp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..94c4838aa0b0be1005e7b0eb1844cd5d7eb4ab1d --- /dev/null +++ b/msigdb_hp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86416992bfa485c449e20bbebfb76806930632474dc9bedecd4557e160930089 +size 138602 diff --git a/msigdb_hp/basic/plot_45.png b/msigdb_hp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..58d548fa205ad5c31b6c278f2ba68be8de91b277 --- /dev/null +++ b/msigdb_hp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f26458033c3ec9abd3c16e0e90a5e61ac7c32d518cbde19f12d73a468b6e2f35 +size 129922 diff --git a/msigdb_hp/basic/plot_46.png b/msigdb_hp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..3ba6883fe1ce31f9752ba4cb36af695287b46294 --- /dev/null +++ b/msigdb_hp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3012dc52a14c0362be6ade2daed5ab6638cdec1c696d640d3c8a5ec69cdc06fe +size 143580 diff --git a/msigdb_hp/basic/plot_47.png b/msigdb_hp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..a8b12821c145d2d7f90cdaaf328eea72dfbb2cd2 --- /dev/null +++ b/msigdb_hp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:683fd5bebbb00e3048fe646d7d1b25fcb2c8a82bb609b0b6e54bfb4e0aec8f48 +size 128686 diff --git a/msigdb_hp/basic/plot_48.png b/msigdb_hp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..eb2e1937500f5054b84f4f7e2dae66bd2de9010c --- /dev/null +++ b/msigdb_hp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2579c07d7379cca79a619adcb56f5ee444daf0572c35adaed493d7a3753215e +size 135151 diff --git a/msigdb_hp/basic/plot_49.png b/msigdb_hp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..fee03d2201b68a318771daeaccf930bf57ca0faa --- /dev/null +++ b/msigdb_hp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c457797c98f02fdf3a9b8afa1f5250280f5ee21c6a2242a46a89f607a5877af +size 142887 diff --git a/msigdb_hp/basic/plot_5.png b/msigdb_hp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..b2df8f29dfe6a365b7d09c5c7d8c04db268a10be --- /dev/null +++ b/msigdb_hp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0dd63e73e55a32f4bf08994b3291198e1abbb8abf788211194156cd64aae285b +size 132110 diff --git a/msigdb_hp/basic/plot_6.png b/msigdb_hp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a40cc25f965d15efe9034fa1938918f22db46305 --- /dev/null +++ b/msigdb_hp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13b1022f33f6ee94fcdfe868c9d581cc3c4b7475fb966628c6e7efcb06c4441a +size 139978 diff --git a/msigdb_hp/basic/plot_7.png b/msigdb_hp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..29a5daec176fe2a443ad51a16ffe15bcb18c24f3 --- /dev/null +++ b/msigdb_hp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c175735ad103de6bd46995d7202a51a8f5cb2cc45bedc36419bd2f33aae16819 +size 130452 diff --git a/msigdb_hp/basic/plot_8.png b/msigdb_hp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..38f83a531072f4209f12ffdd715260d4a1454242 --- /dev/null +++ b/msigdb_hp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92f6361512f6a6b05576daf328779856695396de2a9f7ed34aa03a1303b9b6bd +size 143882 diff --git a/msigdb_hp/basic/plot_9.png b/msigdb_hp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..19f5bc0dc43c9be47d855b00ed5ff78d24eed7af --- /dev/null +++ b/msigdb_hp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:813bde0b861a45186d69df7ab3232d46576ecb1a1915b133afbe8dcc14f6d198 +size 138571 diff --git a/msigdb_hp/consensus.joblib b/msigdb_hp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d128d96ea496533cc9af19ba33f28db810be7dee --- /dev/null +++ b/msigdb_hp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2922f1918979bcdaaa3455bcecadc9b6ea50e0d9efc43d8e71f45fd96fa6281 +size 427532 diff --git a/msigdb_hp/df_merge.tsv b/msigdb_hp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5950fd29e5474b9d6373f62812e688a438b5c57a --- /dev/null +++ b/msigdb_hp/df_merge.tsv @@ -0,0 +1,45 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Abnormal pulmonary interstitial morphology 5 32 3.5374780200459868 0.0004039678078189 6.371359223300971 30.5995145631068 0.4103689768813533 0.4555813960836699 3.330566746297264 2.186076806332745 1.1224431747517174 0.329794447909787 3.299073056927622e-05 0.0001158706789441 0.0136037852653257 0.0431250842600571 +Biliary tract abnormality 9 29 2.9762566620878697 0.002917905443269 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 4.228235977164226e-07 2.261946392785852e-06 0.0001451869950716 0.0009757743848539 +Abnormal muscle fiber morphology 16 66 2.9084314259942983 0.003632468316105 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.0377757515980832 0.1975975208493967 0.0057603049551775 0.0021654451982535 +Abnormal biliary tract morphology 9 26 2.859838961739872 0.0042385618296243 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 1.344884541176363e-07 6.111537107525866e-07 3.65696402570936e-05 0.0002030463281523 +Variable expressivity 17 76 2.7383070535645624 0.0061756386513582 16.655339805825243 76.72572815533981 0.9137081973948464 0.4866305980303022 6.903822328870412 7.203694993346709 1.0588933116250316 0.3878161256963057 0.0721604358488748 0.13970724106502 0.0694249726492539 0.0141814133171121 +Pulmonary fibrosis 3 20 2.7339512291749943 0.0062579312855906 3.934466019417475 19.601941747572816 0.249651568228048 0.5789497476216486 2.416182589767948 1.353455167270249 0.790614601405684 0.2834869501430559 0.0012913565397332 0.0010036685368642 0.0265672828357611 0.0772454186514108 +Wide anterior fontanel 11 26 2.5246291326421457 0.0115820444689405 6.883495145631068 22.87135922330097 0.5984883047357004 0.51093763506043 3.004207311482479 3.16541613655465 0.8343647618961921 0.3244934138131808 0.0310751174278923 0.1112999318055074 0.0571243888921134 0.0005781925850387 +Increased bone mineral density 6 25 2.510758430434478 0.0120472105921511 6.242718446601942 24.75 1.1480702818250033 0.3148175930983396 2.4533156459354677 2.2345749579547443 1.0849696139569316 0.312718333498069 0.005100197971692 0.0058546728506797 0.1123101919918835 0.0763793310526922 +Poor suck 6 29 2.4987271163932 0.0124640246873652 7.12378640776699 26.803398058252423 0.1011748910971412 0.7392549738372975 3.5583509370594073 3.0101266152120383 0.5751431094380084 0.2655047339860314 1.0 0.5083206499791918 0.0333870553509734 0.0681816530513533 +Phenotypic variability 21 99 2.4861488286708804 0.0129133948184412 22.339805825242717 99.4368932038835 0.8464119152872666 0.5170730885331468 8.500203764614474 8.607030207254683 1.0360918895927824 0.3938137781932724 0.1338533855695096 0.1225565745072822 0.0724855476951119 0.015864461604044 +Abnormality of pancreas physiology 6 42 2.4538186274304614 0.0141348254031783 8.33495145631068 41.74514563106796 0.2260468842809028 0.6100794420799563 3.683397775478612 4.537930832541139 0.7462521675115479 0.2917658993245175 0.0117679192899753 0.0166249475514907 0.0124287342519901 0.1292013963829708 +Young adult onset 4 12 2.4457695296538144 0.0144543364734186 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.1376340872498759 0.003389670482849 0.0009447024772989 0.0182596420242621 +Biliary cirrhosis 2 7 2.4268598494275 0.0152301380589539 1.9733009708737863 6.650485436893204 1.1218722294682368 0.279893930524248 1.1603338056285764 0.598683634692072 0.8535321112514973 0.2502325498718601 0.0013329072658427 0.0001725606130307 0.00262770885776 0.0182159139614431 +Vertebral compression fracture 2 17 2.422800935128314 0.0154013635902978 3.718446601941748 15.771844660194176 0.638605685637545 0.4585378455721924 1.8270750975800616 1.3728941491613926 0.8197174983565503 0.2921971535023096 0.0002215840307943 0.0018516158363228 0.0242110622206542 0.0075753503172145 +Hypersplenism 2 7 2.4171927270965377 0.0156407332867545 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 4.92948696733527e-05 0.0004272672884902 0.0062267265321947 0.0401461367370898 +Osteopenia 10 71 2.409113587318043 0.0159913201028287 14.580097087378642 70.14320388349515 0.5468518828167999 0.5898264625753131 5.569149766058337 5.306286565364834 0.7866919750372822 0.3524913522638017 0.001204138033335 0.0063960662505902 0.1327564101294273 0.1466972588118815 +Abnormal activity of mitochondrial respiratory chain 11 51 2.408543351447401 0.0160163239949686 14.847087378640778 52.86407766990291 0.7821137838412346 0.382257667326437 7.203923975365814 5.31995427327111 1.5049815702887546 0.3635380021892623 0.0086553947154521 0.0113667517638714 0.0723391847179421 0.0049769573893231 +Increased circulating antibody level 2 17 2.3819324749282367 0.0172220550953237 3.2402912621359223 15.145631067961164 0.5908116743587006 0.4340890712285613 1.9578142936372311 2.533878285328643 0.9673694377645128 0.2975830104493745 0.0019313424584052 0.0145863017156454 0.1423397245441582 0.2686893480606078 +Abnormality of the anterior fontanelle 12 34 2.3152826184306665 0.0205974703584872 8.439320388349515 32.96844660194175 0.3989308790320728 0.5994637019798429 3.5599862992361873 3.713197992906827 0.7815011046037195 0.3233084287135866 0.0477767109618943 0.1629989722901094 0.1123101919918835 0.0010665292840946 +Thin skin 12 27 2.2995297791715013 0.0214748743795207 5.233009708737864 24.262135922330096 0.5619176829908993 0.56634777500469 2.7153067859181794 2.501305154648419 0.6915958695001003 0.3147007677784247 0.2462339839987873 0.0201824597439383 0.1835520270988697 0.0281223334511535 +Ragged red muscle fibers 3 19 2.296567994613161 0.0216434261803404 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.0138278109504967 0.0528695758908991 0.0142235096743441 0.0396063215160503 +Prenatal movement abnormality 21 64 2.244143836563187 0.0248231482592999 12.398058252427184 58.41504854368932 0.2301808818459553 0.6896691980273608 4.94501770604631 6.063584343829225 0.6421785295244297 0.2980837946342114 0.02696199692994 0.1506786761356137 0.0212516874246769 0.0035910010540877 +Abnormality of humoral immunity 5 63 2.234643166042445 0.0254407845614605 11.274271844660197 56.02669902912621 0.2236266828854534 0.674955898838158 5.483870276333484 5.712935906905208 0.7522335434112123 0.3241379607555358 0.0007183162275431 0.0036659628903284 0.084846500778754 0.1398224860007888 +Pathologic fracture 5 17 2.230061929200164 0.0257433318151758 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.0138278109504967 0.0059531349747588 0.0678108138951911 0.0396063215160503 +Bruising susceptibility 5 29 2.1490185419178136 0.0316329301517674 6.973300970873787 29.92233009708738 0.7164216438132665 0.4493299188905011 2.7915903141815184 3.5959505822612523 0.9221467384175908 0.3249127615519124 0.0748026769142899 0.0665208936005656 0.2135993301405268 0.3437117415394648 +Inflammation of the large intestine 1 14 2.123216337816374 0.0337357275199647 3.3179611650485437 12.66747572815534 0.2339639554441939 0.6035440394025436 2.5463409343274623 1.9254580685340104 0.7774804471623298 0.2946053809815054 0.0197081838633031 0.0734859631006396 0.3157753203157507 0.6752060489618263 +Ascites 3 29 2.0953768803443613 0.0361375030754882 6.538834951456311 25.800970873786408 0.2860997134153194 0.2561597752608451 2.6559964399945706 3.331112387328855 1.6846905274497244 0.2824645045304154 0.0042136201620641 0.0045964910868255 0.0931141624023252 0.2641884401117286 +Decreased activity of mitochondrial complex i 9 35 2.089333015753903 0.0366777563699971 9.281553398058252 33.63834951456311 0.9162605947168436 0.3572379048008119 4.7041965890170365 4.116953486956332 1.2998989973013628 0.34388058367185 0.0229764784753464 0.012498849387857 0.0345596402774107 0.0001452325992069 +Ophthalmoparesis 26 75 2.078517422376629 0.0376617279195392 18.725728155339805 73.37378640776699 0.0515180888850272 0.6373334916546075 7.4103062711939645 7.575900230592595 0.901601792525324 0.3318988936438198 0.2385892709615066 0.3017979485036616 0.057169049606404 0.0686704422761108 +Abnormality of fontanelles 19 47 2.0685508924848937 0.038588250205932 12.533980582524272 46.23543689320388 0.679338498231045 0.5021510160434427 4.713779704909753 4.753170281164529 0.9735403185104452 0.3677424081230729 0.1070124290166615 0.3202129502459803 0.3370386727072499 0.0147921979023582 +Central sleep apnea 1 5 2.0493545564245816 0.0404274574848515 2.0655339805825244 6.118932038834951 0.0875434795443267 0.6145019420335434 1.6334121936842485 0.826109624617783 0.7512946336710279 0.2790856545955639 1.0 1.0 0.307957256786686 0.5276895149825147 +Abnormality of the biliary system 15 121 2.024656028506453 0.0429026967277783 24.728155339805824 113.4878640776699 0.4226772043353868 0.5416117734931738 8.513489210598458 10.938368752781027 1.0946055307638114 0.3805906621326833 0.0001700076204473 3.431504309778164e-05 0.001645390271164 0.0291090687742526 +Centrally nucleated skeletal muscle fibers 2 7 2.0215995318103466 0.0432177404760072 2.6432038834951457 7.385922330097087 0.337303529113138 0.4859248811978309 1.512529363330304 1.4121854830820135 0.9597116029085156 0.3025094388096049 1.0 1.0 0.090818300458346 0.0798154053066686 +Uveitis 1 10 2.014199264980798 0.0439886168398224 2.337378640776699 8.485436893203884 -0.001609160193697 0.5865394934394451 1.7460804712186002 1.5710615894554203 0.8216357094893146 0.2909159328839226 0.1336282364993428 0.0348321279589049 0.1724444479617574 0.1905468417868487 +External ophthalmoplegia 3 15 2.0010761561298698 0.0453841834651136 5.0 17.00242718446602 0.5663831977441792 0.4827064568652057 2.377074975025652 3.293490775365303 0.8939003315322738 0.3080856115403083 1.0 1.0 0.3067990234802971 0.1847754358087514 +Macular degeneration 3 12 1.9870990414845235 0.0469114224539817 3.5072815533980584 13.201456310679612 0.7081764422831481 0.3007939344006393 1.5711122114355351 1.3240485924903622 1.388921785741595 0.3097317018961461 0.214048603403005 0.3924527927004838 0.3601862036851755 0.2469963169810251 +Transposition of the great arteries 4 6 1.9869811485492 0.0469244859446082 1.203883495145631 5.665048543689321 0.7562120366134815 0.4185380653537092 1.1667665326732786 1.0969692349824032 0.827947918729971 0.2809375696957198 0.1534769953785304 0.2915824887707032 0.5870305126491255 0.8350628750672632 +Abnormal saccadic eye movements 11 24 1.9836652433399375 0.0472931706525476 6.293689320388349 24.570388349514563 0.6352395547829492 0.4765898942028741 2.9458970942458165 3.3125821982342476 0.9514629694011908 0.3397171221111555 0.2703718142220204 0.4790872775808428 0.4934040207883591 0.424806821173486 +Abnormal leukocyte physiology 5 70 1.983393270841284 0.0473235181923343 12.00728155339806 62.28398058252427 0.2079341111276809 0.7071752426147094 5.830739215100783 6.432203240250949 0.7011486106506812 0.3175728838622644 0.0010578635255819 0.0055675441345863 0.054656795916593 0.2073444032446952 +Abnormality of exocrine pancreas physiology 3 18 1.9815761811402144 0.0475266952168427 3.5898058252427183 17.783980582524272 0.5068004004363577 0.550464427198069 2.203085427120194 2.2152243918887944 0.746995641290687 0.2986450773348783 0.0125009202076431 0.0051311282902344 0.0118572988629309 0.1040239469578102 +Delayed cranial suture closure 16 32 1.975278319858715 0.0482365721676125 7.716019417475728 29.325242718446603 0.7058204487281402 0.4787858893421486 2.9402522313721624 1.8749870392614547 0.9549766649562498 0.3518038054905379 0.2356515416958359 0.4264955437255276 0.0515621560092188 0.0004366653435552 +Pulmonary infiltrates 1 7 1.9702491887742493 0.0488098186475667 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.1133242047904145 0.2202973788945578 0.1300982938321277 0.3640245481081547 +Adipose tissue loss 7 10 1.966131675310239 0.0492834023263877 2.1966019417475726 8.868932038834952 0.5211940454279882 0.5016959250244486 1.8985656585949904 0.964065937217787 0.805448695400703 0.2886794677399581 1.0 1.0 1.0 0.1199524552735497 +Recurrent aspiration pneumonia 0 5 1.960400413238203 0.0499490076023259 2.0606796116504853 6.25 0.3948833569251968 0.2988616259147967 1.2222482563963537 0.6632700690261994 1.354266830500057 0.2888538147928982 0.0713092569444504 0.1419203898220533 0.3247468214281712 0.5507460232908605 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1860c883ebcb960a5a75366203468d01be282197 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 4636, + "title": "Average number of proteins per term", + "value": 25.00862812769629 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1385d61effae0bef625c05430abe7d2253f1548c --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b4361b3ba65f58c3782491e0f856bd5b078f84b8 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1511 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Abnormal pulmonary interstitial morphology 0.6872004274013008 3.5374780200459868 0.0004039678078189 0.8463646180179065 0.021843470767927 32 Q9UJW0,P09601,P04062,Q14108,P57076 5 +Verrucae 0.92535085100029 3.1180163225137867 0.0018207271970429 0.9997857966811124 0.0444257436078482 2 Q13043 1 +Left ventricular noncompaction cardiomyopathy 0.9244550612122976 3.1140649617158034 0.00184528856932 0.9998088898374928 0.0447893078919788 2 Q15233 1 +Unilateral cleft palate 0.9151985667363344 3.0731243585450136 0.0021183019196417 0.999946233703608 0.0467640366640922 2 Q12959 1 +Irregular capital femoral epiphysis 0.9128097939683496 3.0625263986014395 0.0021947711573466 0.9999623109630704 0.0474945730353288 2 Q9NUQ7 1 +Temporal optic disc pallor 0.9110182143923578 3.0545691063299025 0.0022538408256627 0.99997135692239 0.0474945730353288 2 O00429 1 +Anomalous trichromacy 0.9110182143923578 3.0545691063299025 0.0022538408256627 0.99997135692239 0.0474945730353288 2 O00429 1 +Tritanomaly 0.9110182143923578 3.0545691063299025 0.0022538408256627 0.99997135692239 0.0474945730353288 2 O00429 1 +Morning glory anomaly 0.9110182143923578 3.0545691063299025 0.0022538408256627 0.99997135692239 0.0474945730353288 2 O00429 1 +Reactive hypoglycemia 0.9026575097043896 3.0173347374606867 0.0025500804616331 0.9999927700066504 0.0494366641768691 2 P00367 1 +Biliary tract abnormality 0.6307952582057996 2.9762566620878697 0.002917905443269 0.9999986922258158 0.0532575182480137 29 Q9UJW0,P14174,P50542,Q13043,P07602,P09601,P04062,Q14108,Q10713 9 +Branchial cyst 0.8886234696924362 2.9544602053337963 0.003132165456166 0.9999995171246536 0.0558489194414832 2 Q9UHX1 1 +Dysgenesis of the cerebellar vermis 0.8868318901164485 2.9463997146629177 0.0032149665061567 0.9999996714560008 0.0564849194113796 2 Q10713 1 +Abnormal muscle fiber morphology 0.4792078335565733 2.9084314259942983 0.003632468316105 0.9999999528901152 0.0626026881541382 66 Q86U42,Q9HA77,P53007,Q70HW3,Q9H2D1,P06753,P23786,O60313,P12235,O43676,Q15650,P50570,P46976,O14979,P31483,Q7Z392 16 +Low molecular weight proteinuria 0.8710062705285172 2.8748621602879645 0.0040420391595483 0.9999999929965824 0.06691143638569 2 Q01968 1 +Bicarbonaturia 0.8710062705285172 2.8748621602879645 0.0040420391595483 0.9999999929965824 0.06691143638569 2 Q01968 1 +Abnormal biliary tract morphology 0.6411135099441557 2.859838961739872 0.0042385618296243 0.9999999971946416 0.069190044514572 26 Q9UJW0,P14174,P50542,Q13043,P07602,P09601,P04062,Q14108,Q10713 9 +Symphalangism affecting the phalanges of the hand 0.8620483726485387 2.834099522063976 0.004595501776806 0.9999999994677192 0.0724651232560329 2 Q15233 1 +Proximal symphalangism 0.8620483726485387 2.834099522063976 0.004595501776806 0.9999999994677192 0.0724651232560329 2 Q15233 1 +Osteopetrosis 0.8620483726485345 2.8340995220639607 0.0045955017768062 0.9999999994677192 0.0724651232560329 2 Q15392 1 +Silver gray hair 0.8569722305165683 2.810913578058913 0.0049401053126292 0.9999999998930956 0.0749870048418842 2 P51159 1 +Spotty hypopigmentation 0.8530904747685903 2.7931404690195496 0.0052199019281133 0.9999999999709744 0.0760989476060937 2 Q15125 1 +Agenesis of maxillary incisor 0.8530904747685821 2.7931404690194945 0.0052199019281142 0.9999999999709744 0.0760989476060937 2 P41227 1 +Erlenmeyer flask deformity of the femurs 0.9323861312855176 2.759472951932028 0.0057894679510357 0.9999999999979596 0.0817550597189083 3 P04062 1 +Joint hemorrhage 0.8444311734846186 2.753359006264329 0.0058987172060085 0.9999999999987742 0.0817550597189083 2 P38435 1 +Respiratory insufficiency due to defective ciliary clearance 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Abnormal respiratory motile cilium morphology 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Nasal congestion 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Abnormal respiratory motile cilium physiology 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Absent outer dynein arms 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Abnormal atrial arrangement 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Abnormal nasal mucosa morphology 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Wheezing 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Absent shortened dynein arms 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Chronic bronchitis 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.9999999999995748 0.0818650004384473 2 P57076 1 +Variable expressivity 0.447200919529876 2.7383070535645624 0.0061756386513582 0.9999999999996632 0.0819777997469436 76 Q09472,Q9Y263,Q70HW3,P35240,P07602,P06753,Q969Y2,Q15125,P46976,O00429,Q13813,Q9H061,P23258,P04350,Q6P4A7,P00374,P41227 17 +Pulmonary fibrosis 0.6899414499939897 2.7339512291749943 0.0062579312855906 0.9999999999997704 0.0821863156940454 20 Q9UJW0,P04062,P09601 3 +Oligospermia 0.8354732756046588 2.712010628207298 0.0066876448513468 0.9999999999999692 0.0842497867686177 2 P54132 1 +Elbow ankylosis 0.8354732756046596 2.712010628207298 0.0066876448513468 0.9999999999999692 0.0842497867686177 2 P48651 1 +Humeroradial synostosis 0.8354732756046596 2.712010628207298 0.0066876448513468 0.9999999999999692 0.0842497867686177 2 P48651 1 +Synostosis of metacarpals metatarsals 0.8354732756046416 2.712010628207221 0.0066876448513484 0.9999999999999692 0.0842497867686177 2 Q15233 1 +Acromesomelia 0.8190504628247277 2.635687024353978 0.008396713902673 1.0 0.0976262141902483 2 P63000 1 +Short proximal phalanx of finger 0.8190504628247235 2.635687024353951 0.0083967139026737 1.0 0.0976262141902483 2 P42345 1 +Abnormal 5th finger phalanx morphology 0.8190504628247053 2.6356870243538792 0.0083967139026754 1.0 0.0976262141902483 2 Q9UHX1 1 +Buphthalmos 0.8172588832487351 2.627320087129944 0.0086060337853153 1.0 0.098078868537312 2 Q01968 1 +Aplasia of the phalanges of the toes 0.8133771275007455 2.6091641670635415 0.0090763687388497 1.0 0.0993729808332372 2 Q08AM6 1 +Sclerosis of hand bone 0.8133771275007405 2.6091641670635166 0.0090763687388504 1.0 0.0993729808332372 2 Q15125 1 +2 3 toe cutaneous syndactyly 0.8106897581367618 2.596572575974308 0.0094159011512515 1.0 0.1019570574087947 2 P27635 1 +Prominent antitragus 0.8065094057927739 2.576949668209606 0.0099676463432403 1.0 0.10454753042367 2 Q92643 1 +Moderately reduced visual acuity 0.8870967741935464 2.567867433094301 0.0102326280194489 1.0 0.1065481398645554 3 O00429,O60313 2 +Dilatation of the ventricular cavity 0.8041206330247861 2.56571689288801 0.0102962827133989 1.0 0.1065481398645554 2 P27635 1 +Abnormal thalamic size 0.8041206330247831 2.5657168928879948 0.0102962827133994 1.0 0.1065481398645554 2 Q9UPT5 1 +Congenital muscular dystrophy 0.8041206330247821 2.565716892887987 0.0102962827133996 1.0 0.1065481398645554 2 P02545 1 +Laryngeal dystonia 0.8017318602567851 2.554469792062154 0.0106349657348299 1.0 0.1083223328821417 2 P04350 1 +Aplasia hypoplasia of the colon 0.8014332636607929 2.553062896877583 0.010678021166337 1.0 0.1083223328821417 2 P02545 1 +Epidermal hyperkeratosis 0.8014332636607929 2.553062896877583 0.010678021166337 1.0 0.1083223328821417 2 P02545 1 +Prominent umbilicus 0.8014332636607929 2.553062896877583 0.010678021166337 1.0 0.1083223328821417 2 P02545 1 +Wide anterior fontanel 0.5926761932515829 2.5246291326421457 0.0115820444689405 1.0 0.1146754837449203 26 Q09472,P50542,P16435,Q32P28,O15111,O75718,Q15125,O75381,P40855,Q9H6U8,Q9Y487 11 +Increased bone mineral density 0.6020362565179583 2.510758430434478 0.0120472105921511 1.0 0.1175807753793956 25 P18074,Q15125,P04062,Q13126,Q14108,Q15392 6 +Poor suck 0.5654795463664402 2.4987271163932 0.0124640246873652 1.0 0.1201314312902817 29 Q9Y263,P50542,P53007,Q15233,P22695,Q12959 6 +Phenotypic variability 0.4158956982072148 2.4861488286708804 0.0129133948184412 1.0 0.1220702791078839 99 Q09472,Q70HW3,P35240,Q969Y2,Q15125,P46976,P04350,P23258,P00374,Q9Y263,P07602,O60313,Q08426,P36551,P06753,O00429,Q9H061,Q6P4A7,P41227,O14979,Q13813 21 +Bilateral cleft palate 0.8676612322558227 2.484338426301804 0.0129792393126246 1.0 0.1220702791078839 3 O15111 1 +Optic disc coloboma 0.8657671307576037 2.4761560259601585 0.0132805526448001 1.0 0.1236318113680588 3 Q10713 1 +Synostosis involving digits 0.8623058542413341 2.461184233879419 0.0138479235835387 1.0 0.1271266806599711 3 Q15233,Q9H1A4 2 +Abnormality of pancreas physiology 0.4960270949082492 2.4538186274304614 0.0141348254031783 1.0 0.1284415537826643 42 Q9UJW0,P14174,Q13043,Q9UHX1,P09601,P53985 6 +Young adult onset 0.7719541418422581 2.4457695296538144 0.0144543364734186 1.0 0.1294023313021212 12 P07602,P38435,P36551,Q14566 4 +Upper limb postural tremor 0.8548387096774155 2.428800089749249 0.0151488826528205 1.0 0.132556206847191 3 Q9HA77,P04350 2 +Biliary cirrhosis 0.8761672556841733 2.4268598494275 0.0152301380589539 1.0 0.1328723794072687 7 Q9UJW0,P09601 2 +Chronic hepatic failure 0.9339564008905908 2.424736952835898 0.0153194823526541 1.0 0.1328723794072687 4 Q13043 1 +Abnormal mitochondrial number 0.8538842702294795 2.4246524337178137 0.0153230489578908 1.0 0.1328723794072687 3 P51530 1 +Vertebral compression fracture 0.6796782763220792 2.422800935128314 0.0154013635902978 1.0 0.1331422613012197 17 Q32P28,P04062 2 +Agenesis of lateral incisor 0.8533452807646316 2.42230933911566 0.0154222162033552 1.0 0.1331422613012197 3 Q12959,P41227 2 +Incomprehensible speech 0.7736637802329049 2.421241988410052 0.0154675768573224 1.0 0.133285662287262 2 Q8WXI9 1 +Hypersplenism 0.8739162603041961 2.4171927270965377 0.0156407332867545 1.0 0.1345277171009165 7 Q14108,P04062 2 +Osteopenia 0.4279390274660239 2.409113587318043 0.0159913201028287 1.0 0.1365942922962698 71 Q9H1A4,O60568,Q13043,P07602,Q32P28,P04062,Q13126,Q14108,P17252,Q9Y487 10 +Abnormal activity of mitochondrial respiratory chain 0.461195433658975 2.408543351447401 0.0160163239949686 1.0 0.1365942922962698 51 Q9HA77,Q9P0J0,Q70HW3,P51970,O75380,Q969Y2,Q9UBX3,Q96EY7,O43676,Q86Y39,O75306 11 +Broad femoral neck 0.7697820244849057 2.402660998396221 0.0162762681387986 1.0 0.137795998414438 2 Q9NUQ7 1 +Focal cortical dysplasia type ii 0.7688862346969267 2.3983677056831048 0.0164683241352205 1.0 0.137795998414438 2 P42345 1 +Hemimegalencephaly 0.7688862346969267 2.3983677056831048 0.0164683241352205 1.0 0.137795998414438 2 P42345 1 +Chorioretinal hypopigmentation 0.7688862346969243 2.398367705683095 0.016468324135221 1.0 0.137795998414438 2 Q96AX1 1 +Abnormality of the subungual region 0.7688862346969079 2.398367705683016 0.0164683241352245 1.0 0.137795998414438 2 P16615 1 +Confetti like hypopigmented macules 0.7688862346968991 2.3983677056829715 0.0164683241352265 1.0 0.137795998414438 2 Q15233 1 +Vertical nystagmus 0.7656016721409271 2.382608408647722 0.0171904696150311 1.0 0.1413122963219835 2 P50542 1 +Increased circulating antibody level 0.6725978921716156 2.3819324749282367 0.0172220550953237 1.0 0.1413122963219835 17 Q14108,P04062 2 +St segment elevation 0.8393822858759861 2.3613990171332855 0.0182061295973916 1.0 0.1483367606564282 3 Q99996 1 +Abnormal st segment 0.8393822858759861 2.3613990171332855 0.0182061295973916 1.0 0.1483367606564282 3 Q99996 1 +Unilateral cleft lip 0.758733950432951 2.349569787306039 0.0187951204378955 1.0 0.1520666288832177 2 Q92993 1 +Increased laxity of ankles 0.755449387876982 2.3337269921946975 0.0196100217784966 1.0 0.1570156493352515 2 Q96C36 1 +Hyperesthesia 0.8313214517737211 2.3260513870573 0.0200158094777855 1.0 0.1597130683976144 3 P07602 1 +Posterior pharyngeal cleft 0.752762018512968 2.3207446652914525 0.0203006285566762 1.0 0.1611536198437518 2 O15344 1 +Abnormality of the anterior fontanelle 0.515426806878352 2.3152826184306665 0.0205974703584872 1.0 0.1626743996285296 34 Q09472,Q9UQE7,P50542,P16435,Q32P28,O15111,O75718,Q15125,O75381,P40855,Q9H6U8,Q9Y487 12 +Cold induced muscle cramps 0.7509704389370011 2.3120797735398675 0.0207732875713138 1.0 0.1637839475860727 2 P23786 1 +Recurrent mycobacterial infections 0.826021799415644 2.3027386392112437 0.0212935527902513 1.0 0.1659345804426502 3 P57076 1 +Breathing dysregulation 0.8257143586073283 2.3013844531712446 0.0213699098993256 1.0 0.1659345804426502 3 Q10713 1 +Thin skin 0.5541139799733836 2.2995297791715013 0.0214748743795207 1.0 0.1659345804426502 27 P18074,O15111,Q96PU5,O14802,P48651,Q6ZXV5,P02545,P19447,Q13126,O75431,P17252,O75844 12 +Ragged red muscle fibers 0.6272328362314282 2.296567994613161 0.0216434261803404 1.0 0.1663777291238631 19 Q9H2D1,Q9HA77,Q70HW3 3 +Increased muscle fatiguability 0.8243477027885102 2.295362379962678 0.0217123654270787 1.0 0.1663777291238631 3 P53985 1 +Exercise induced muscle fatigue 0.8243477027885102 2.295362379962678 0.0217123654270787 1.0 0.1663777291238631 3 P53985 1 +Decreased ldl cholesterol concentration 0.8229224240168646 2.289077890614973 0.02207482717374 1.0 0.1681076678969542 3 Q15800 1 +Muscle fiber necrosis 0.7461928934010157 2.288934323426612 0.0220831686258007 1.0 0.1681076678969542 2 O60231 1 +Nocturia 0.7461928934009909 2.28893432342649 0.0220831686258078 1.0 0.1681076678969542 2 P12235 1 +Multiple mitochondrial dna deletions 0.7461928934009909 2.28893432342649 0.0220831686258078 1.0 0.1681076678969542 2 P12235 1 +Noncompaction cardiomyopathy 0.8947987651959088 2.2673692919476753 0.0233676757629566 1.0 0.1736098474952994 4 Q15233 1 +Square face 0.8173862721910422 2.2646276789546738 0.0235355369019512 1.0 0.1743848245844963 3 Q9UHX1 1 +Prenatal movement abnormality 0.4224504764389916 2.244143836563187 0.0248231482592999 1.0 0.1807015205916365 64 Q9UQE7,Q70HW3,Q6P3W7,P50570,Q9Y5P6,P04062,P40855,O15111,Q9H6U8,Q96F07,P51530,Q9HC21,Q4J6C6,P06753,Q15650,O00429,Q96S52,Q9GZZ9,Q9UM00,P53007,P02545 21 +Aplasia hypoplasia of the retina 0.7357420125410601 2.2381062490832853 0.0252141272458219 1.0 0.1823598968980324 2 Q9Y4I1 1 +Abnormal foveal morphology 0.7357420125410552 2.238106249083258 0.0252141272458237 1.0 0.1823598968980324 2 P35221 1 +Abnormality of humoral immunity 0.4226099433642067 2.234643166042445 0.0254407845614605 1.0 0.182449533379836 63 Q9UJW0,Q13043,P09601,P04062,Q14108 5 +Pathologic fracture 0.6465557035004097 2.2300619292001636 0.0257433318151758 1.0 0.182449533379836 17 O60568,P04062,Q13126,Q14108,Q01968 5 +Breast aplasia 0.7300686772170821 2.2104010125029214 0.0270773436016247 1.0 0.1876391105188976 2 P02545 1 +Aplastic clavicle 0.7300686772170761 2.2104010125028895 0.0270773436016269 1.0 0.1876391105188976 2 P48651 1 +Contractures of the large joints 0.8022700119474254 2.19754787137234 0.0279813415003964 1.0 0.1912209072094312 3 Q9Y263,P50542 2 +Complete atrioventricular canal defect 0.8018431350645705 2.1956468147360138 0.0281172326798742 1.0 0.1912209072094312 3 Q9UHX1 1 +Prominent ear helix 0.8016726403823156 2.194887429325615 0.0281716737756756 1.0 0.1912209072094312 3 P02545,Q96N67 2 +Severe failure to thrive 0.8016726403823153 2.194887429325612 0.0281716737756758 1.0 0.1912209072094312 3 P02545,Q08AM6 2 +Patchy alopecia 0.8016726403823154 2.194887429325612 0.0281716737756758 1.0 0.1912209072094312 3 P02545,P54132 2 +Aortic valve calcification 0.8016726403823099 2.1948874293255876 0.0281716737756776 1.0 0.1912209072094312 3 P02545,P04062 2 +Abnormal sweat gland morphology 0.8016726403823101 2.1948874293255876 0.0281716737756776 1.0 0.1912209072094312 3 O15111,P02545 2 +Chronic sinusitis 0.7971160184336219 2.1745704029229453 0.0296623242631577 1.0 0.1964493361199989 3 P57076 1 +Choanal stenosis 0.7953674218737974 2.1667626542971035 0.0302529564222147 1.0 0.198413893192019 3 P48651 1 +Dysmenorrhea 0.7208121827411196 2.1650286092421247 0.0303854944102135 1.0 0.198413893192019 2 P02545 1 +Long penis 0.7208121827411142 2.1650286092421016 0.0303854944102153 1.0 0.198413893192019 2 O14802 1 +Pain insensitivity 0.7943775684693096 2.162340081697637 0.0305919723802787 1.0 0.1987565931056724 3 O15269 1 +Anteverted ears 0.7202149895491075 2.162094197601268 0.0306109161944456 1.0 0.1987565931056724 2 P27635 1 +Elevated serum acid phosphatase 0.7914014172318639 2.149031066356356 0.0316319373887912 1.0 0.202552495975355 3 P07602 1 +Bruising susceptibility 0.5196681542453175 2.1490185419178136 0.0316329301517674 1.0 0.202552495975355 29 P38435,O60568,P04062,Q13126,Q14108 5 +Long thorax 0.7866300561150301 2.127657092609414 0.033365524868703 1.0 0.2087484119990651 3 P41227 1 +Inflammation of the large intestine 0.6704529708543346 2.123216337816374 0.0337357275199647 1.0 0.2099419290644587 14 P08183 1 +High frequency sensorineural hearing impairment 0.7843215588241945 2.117299578176759 0.0342344306863111 1.0 0.2121802415263884 3 P02545 1 +Short umbilical cord 0.7828676417377647 2.1107708729303054 0.0347920108397463 1.0 0.2136367711961115 3 P02545 1 +Small placenta 0.7828676417377647 2.1107708729303054 0.0347920108397463 1.0 0.2136367711961115 3 P02545 1 +Corneal erosion 0.7824820405657664 2.109038657377494 0.0349412449905544 1.0 0.2141274107312028 3 P51648 1 +Cortical cataract 0.78076463560334 2.101320079857431 0.0356128782496472 1.0 0.2158186974710646 3 Q01968,P35240 2 +Ascites 0.5127780122772282 2.0953768803443613 0.0361375030754882 1.0 0.2179530553200675 29 Q14108,P04062,Q13043 3 +Female infertility 0.7785729596867297 2.091461521453923 0.0364867122537684 1.0 0.2193935123326464 3 P57076 1 +Decreased activity of mitochondrial complex i 0.4837900911491527 2.089333015753903 0.0366777563699971 1.0 0.2194253730608157 35 Q9HA77,Q70HW3,P51970,Q969Y2,Q9UBX3,Q96EY7,O43676,Q86Y39,O75306 9 +Polysplenia 0.7774995020902223 2.08662946392156 0.0369216417894349 1.0 0.2202943775235781 3 P57076 1 +Torsade de pointes 0.7765679331925686 2.0824342694742013 0.0373028209563122 1.0 0.22142878099035 3 Q99996 1 +Ophthalmoparesis 0.3948803358338786 2.078517422376629 0.0376617279195392 1.0 0.2229882128160715 75 O43678,P35240,P50570,P04062,Q92620,Q9P0J0,P50213,O60318,O60313,P51530,Q06210,Q10713,O75306,O75695,P06753,Q8WWY3,O00429,Q96RR1,Q969G3,P30038,Q86U42,P53007,O43395,P12235,O43819,O43837 26 +Abnormality of fontanelles 0.4411727461401937 2.0685508924848937 0.038588250205932 1.0 0.2255928473577565 47 Q09472,Q9UQE7,Q32P28,Q15125,O75381,P40855,O75844,Q9Y487,P50542,P16435,O15111,P42345,O14802,Q9H6U8,P54886,Q01082,O75718,P48651,P02545 19 +Non midline cleft palate 0.8457174225616799 2.0663946244834612 0.038791233099511 1.0 0.2264939000621325 4 O15111,Q12959 2 +Central sleep apnea 0.8272667656082026 2.0493545564245816 0.0404274574848515 1.0 0.2323660427904516 5 P53007 1 +Lactose intolerance 0.7691878015614413 2.0491389220518146 0.0404485324702101 1.0 0.2323660427904516 3 Q14566 1 +Partial albinism 0.7687810699977301 2.0473008806030624 0.0406285515004227 1.0 0.2326423898759546 3 P51159 1 +Nemaline bodies 0.7686340562372578 2.046636438893671 0.0406937942884868 1.0 0.2326423898759546 3 O43676 1 +First degree atrioventricular block 0.7674380547202364 2.0412294520230008 0.0412280255592962 1.0 0.233555608664952 3 Q99996 1 +Periportal fibrosis 0.6945356822932013 2.035107164413374 0.0418400912687451 1.0 0.2362614654347165 2 Q9H6U8 1 +Abnormality of the biliary system 0.3708471497928767 2.0246560285064534 0.0429026967277783 1.0 0.2405041137000973 121 Q9UJW0,P14174,P36551,Q00059,Q13043,P07602,P09601,P51159,P04062,O75381,Q10713,Q14108,P53004,P55263,P00374 15 +Centrally nucleated skeletal muscle fibers 0.7837502533223354 2.0215995318103466 0.0432177404760072 1.0 0.2419775903946492 7 P06753,Q15650 2 +Uveitis 0.7242494460522513 2.014199264980798 0.0439886168398224 1.0 0.2449155018433736 10 Q13043 1 +Agyria 0.8321937335613111 2.010312543610688 0.0443981201145784 1.0 0.2449155018433736 4 P23258 1 +Stiff skin 0.7589605734766983 2.002824989069482 0.0451960766558503 1.0 0.2474798402699316 3 P02545,O75844 2 +External ophthalmoplegia 0.6351599237122978 2.0010761561298698 0.0453841834651136 1.0 0.2478222315009032 15 P51530,O60313,P12235 3 +Lagopthalmos 0.7571684587813577 1.994688867688336 0.0460768242938605 1.0 0.2507184946318513 3 P02545,O75844 2 +Hypopigmentation of the fundus 0.7567331901713861 1.992711851170549 0.0462930089102955 1.0 0.2513049055130329 3 P38435 1 +Macular degeneration 0.6824055524058973 1.9870990414845235 0.0469114224539817 1.0 0.2529557172548884 12 P51648,P04062,P50897 3 +Transposition of the great arteries 0.7983466822461314 1.9869811485491995 0.0469244859446082 1.0 0.2529557172548884 6 Q86Y56,P57076,Q2TAL8,P02545 4 +Abnormal saccadic eye movements 0.5366584557658178 1.9836652433399375 0.0472931706525476 1.0 0.2541935420890813 24 O14773,P34897,O43819,Q9NXN4,Q8IV08,P49959,P04062,O95140,O60231,Q10713,O75306 11 +Abnormal leukocyte physiology 0.3937678089730818 1.983393270841284 0.0473235181923343 1.0 0.2541935420890813 70 Q9UJW0,Q13043,P09601,P04062,Q14108 5 +Subcortical band heterotopia 0.8256202938133359 1.9829462857257532 0.0473734297594836 1.0 0.2541935420890813 4 O00139,P23258 2 +Subcortical heterotopia 0.8256202938133359 1.9829462857257532 0.0473734297594836 1.0 0.2541935420890813 4 O00139,P23258 2 +Abnormality of exocrine pancreas physiology 0.5910076622152938 1.9815761811402144 0.0475266952168427 1.0 0.2547211086997489 18 Q9UJW0,P14174,P09601 3 +Delayed cranial suture closure 0.4831165337039976 1.975278319858715 0.0482365721676125 1.0 0.2577447448178505 32 Q09472,P54886,Q9UQE7,P16435,Q32P28,O75718,O14802,P48651,P02545,O75381,P40855,Q9H6U8,O75431,O75844,Q9Y487,P41227 16 +Pulmonary infiltrates 0.7723047023398477 1.9702491887742497 0.0488098186475667 1.0 0.2590087224930006 7 P04062 1 +Undetectable electroretinogram 0.7517921146953319 1.970244218539789 0.0488103879973074 1.0 0.2590087224930006 3 P50897,O14773 2 +Adipose tissue loss 0.7144801387399949 1.966131675310239 0.0492834023263877 1.0 0.2598373772065608 10 P18074,Q03252,P54132,P02545,P19447,O75431,O75844 7 +Large placenta 0.750602540152261 1.9648282697387311 0.0494341170612999 1.0 0.2598373772065608 3 P02545 1 +Chronic axonal neuropathy 0.679307255897277 1.9590744436190937 0.050104069243066 1.0 0.2612851124981489 2 O15269 1 +Depletion of mitochondrial dna in muscle tissue 0.8193134300824669 1.9566254577690771 0.0503915196706901 1.0 0.2622082925546405 4 Q9UBX3 1 +Aplasia hypoplasia of the skin 0.4042846158415245 1.9566025353592336 0.0503942167097033 1.0 0.2622082925546405 58 O15111,Q96PU5,Q15125,Q6ZXV5,Q03001,Q15126,Q13126,Q9H6U8,Q9H1A4,P17252,P53701,Q15392 12 +Macular dystrophy 0.6775156763212815 1.950095011475174 0.0511647957304028 1.0 0.2647321350515042 2 Q9Y4I1 1 +Abnormal cellular phenotype 0.3076722931177425 1.9408044110636176 0.052282005783713 1.0 0.2693104209036594 200 Q9UJW0,Q70HW3,P35240,Q969Y2,O43676,Q96EY7,P04062,P46976,Q14108,Q9HA77,Q9P0J0,P50542,Q13043,P07602,P51970,P13051,P09601,Q08426,P51530,Q4J6C6,O75306,P14174,Q9UBX3,O00429,Q86Y39,P18074,O75380,P23786,P51159,P12235,Q15126,P26038,Q01968 33 +Abnormality of amino acid metabolism 0.7442457598250141 1.935842462056692 0.0528869985436433 1.0 0.2704074924855943 3 P18074 1 +Open mouth 0.4697476723530831 1.930753794156376 0.0535135069180074 1.0 0.2729247723563066 34 Q15233,Q86XL3,Q03001,P04062,P04350,P63000,Q10713 7 +Increased skull ossification 0.671842340997311 1.921613391815575 0.0546544222569251 1.0 0.2772187107036161 2 P54802 1 +Abnormal circulating long chain fatty acid concentration 0.79559140100276 1.914520812157898 0.0555536424688551 1.0 0.2802466664696547 5 O75381,P40855,P50542 3 +Brushfield spots 0.8088683209274098 1.912898037541292 0.0557611068665506 1.0 0.280878782614381 4 O75381,P50542 2 +Fluctuations in consciousness 0.7568793259811515 1.9006629195545337 0.057346178389763 1.0 0.2867600521678351 7 P04062,O75306 2 +Bronchitis 0.7916891118246598 1.8977966387618912 0.0577228761767973 1.0 0.2869982392590727 5 P57076,P54132 2 +Saccadic smooth pursuit 0.7356190046191395 1.8963882004007089 0.0579087310025556 1.0 0.2869982392590727 3 Q10713 1 +Supraventricular tachycardia 0.788557596872284 1.884358436394107 0.0595165079328618 1.0 0.2924763127357691 5 Q8NFF5,Q99996,P41227 3 +Loss of subcutaneous adipose tissue in limbs 0.8019121601434172 1.8836844458106172 0.059607671600822 1.0 0.2924763127357691 4 O75431,P02545,Q03252 3 +Cardiac valve calcification 0.8019121601433906 1.8836844458105104 0.0596076716008364 1.0 0.2924763127357691 4 O75431,P02545,P04062 3 +Mitral valve calcification 0.8019121601433906 1.8836844458105104 0.0596076716008364 1.0 0.2924763127357691 4 O75431,P02545,P04062 3 +Status epilepticus with prominent motor symptoms 0.7323549899333706 1.881425596975568 0.059914047593341 1.0 0.2933483774664277 3 P50542 1 +Abnormal sperm motility 0.7741661156523202 1.881363092151742 0.059922543887124 1.0 0.2933483774664277 6 P57076,Q9UBS4,Q8N8E3,Q9H6U8 4 +Middle age onset 0.6970579492294608 1.8798902501112356 0.0601230369631635 1.0 0.293793250802713 10 P07602,Q15126 2 +Gingival bleeding 0.6969740625196814 1.879473432316523 0.0601798778517812 1.0 0.293793250802713 10 P04062 1 +Malabsorption 0.4103456437115745 1.8790151557622952 0.0602424238303413 1.0 0.293793250802713 51 P18074,Q9UJW0,P14174,P50542,P09601,O75381,Q14566,Q01968 8 +Generalized clonic seizure 0.7519307158746955 1.8782488857370736 0.0603471254089813 1.0 0.2938752871807117 7 P07602 1 +Abnormality of the leydig cells 0.6628844431173473 1.876500354901964 0.0605866060129303 1.0 0.2944229617148831 2 P52788 1 +Abnormal urine sodium concentration 0.6628844431173304 1.87650035490188 0.0605866060129418 1.0 0.2944229617148831 2 Q08426 1 +Social and occupational deterioration 0.7307973255467798 1.8742784743598615 0.0608920528194942 1.0 0.295597441749922 3 Q09472 1 +Pedal edema 0.7119624404663347 1.870260618621084 0.0614476354491062 1.0 0.2976710950282722 9 Q14108,P04062 2 +Reduced sperm motility 0.7831603651267722 1.861161584517737 0.0627213615131854 1.0 0.3020972721039295 5 P57076,Q8N8E3,Q9H6U8 3 +Abnormality of the pulmonary veins 0.7480789286479872 1.860773185358549 0.0627762137206033 1.0 0.3020972721039295 7 O75718,P57076,Q15392 3 +Progeroid facial appearance 0.7256262970132545 1.8572415094706551 0.0632768017958818 1.0 0.3027360713371599 8 Q03252,P02545,P19447,O75431,O75844 5 +Microretrognathia 0.6099784022734398 1.8563990585761176 0.0633966988283023 1.0 0.3029970059464017 15 P53007,Q9UHX1,Q15650,Q15125,Q9H6U8,P41227 6 +Functional abnormality of male internal genitalia 0.4601637284282925 1.848455820741224 0.0645364298741886 1.0 0.3065480419023959 34 P16435,Q8N8E3,P54132,P04062,Q86Y56,Q9H6U8,Q9H1A4,P57076,Q9UBS4,Q01968 10 +Shoulder girdle muscle weakness 0.6555018000816952 1.845223294583419 0.0650050632386565 1.0 0.3081426106077828 12 P07602,O14979,P12235,P06753 4 +Fetal akinesia sequence 0.7657028920499792 1.844167859638584 0.0651586807935284 1.0 0.3085553055758918 6 P04062 1 +Congenital onset 0.3610168315372895 1.8372699391879976 0.0661700553281903 1.0 0.3123873487795217 117 Q09472,O43678,Q03252,P34897,Q9UHX1,Q15125,Q9Y5P6,P50570,P25705,O95630,Q92993,Q9Y263,P50542,P07602,O15111,Q5T160,Q9H6U8,Q9HC21,Q4J6C6,P42356,Q2TAL8,Q00059,P06753,Q96PU5,P51571,P08670,Q9H078,Q15650,Q96EK5,P17252,Q9BW92,Q9UHB7,P41227,Q7LGA3,Q86XI2,P12235,Q96N66,Q8NB49,P27635,P51608,Q9Y3D3 41 +Limb girdle muscle weakness 0.4973501008342343 1.8291347242104727 0.0673794281897623 1.0 0.3142565684987308 26 P53007,P07602,P06753,O60313,P12235,Q13126,P51530,O14979 8 +Abdominal pain 0.3685224369014914 1.8253859181202128 0.0679428128165695 1.0 0.3149952506369117 89 P14174,P36551,Q70HW3,Q13043,P04062,Q14108,Q14566 7 +Lambdoidal craniosynostosis 0.7192353643966489 1.8210970705273808 0.0685921025222047 1.0 0.3149952506369117 3 P16435,P61978 2 +Abnormality of lysosomal metabolism 0.7870143397675256 1.8208781250488768 0.0686253850802902 1.0 0.3149952506369117 4 P07602 1 +Large iliac wing 0.6518363690653939 1.8206290639821352 0.0686632617346265 1.0 0.3149952506369117 2 Q13485 1 +Atlantoaxial abnormality 0.6518363690653937 1.8206290639821352 0.0686632617346265 1.0 0.3149952506369117 2 O14802 1 +Long upper lip 0.651836369065393 1.820629063982134 0.0686632617346267 1.0 0.3149952506369117 2 Q9Y2D4 1 +Abnormal pericardium morphology 0.6328088016026299 1.815975625337811 0.0693741112381003 1.0 0.3153121369606207 13 Q14108,P04062 2 +Slender long bone 0.6474130994108864 1.8022318532034856 0.0715089351184348 1.0 0.3231144475721869 12 Q32P28,Q9Y487 2 +Extra axial cerebrospinal fluid accumulation 0.7129447086292666 1.792067570093585 0.073122142922873 1.0 0.3278474415768271 3 Q03252 1 +Abnormal metabolic brain imaging by mrs 0.5825896929780365 1.7696150473418066 0.0767912904431644 1.0 0.3405085544425103 16 P07602,O00429,Q9Y6N5 3 +Multiple prenatal fractures 0.7260810846423974 1.760489959688825 0.0783247683873424 1.0 0.3450042014174818 7 P06753,Q32P28,Q15650 3 +Decreased urine output 0.6392953120334438 1.7569122635640049 0.0789327649906537 1.0 0.3465267978188168 2 P07741 1 +Oliguria 0.6392953120334438 1.7569122635640049 0.0789327649906537 1.0 0.3465267978188168 2 P07741 1 +Menorrhagia 0.7041313959368742 1.7512893084558268 0.0798960884324282 1.0 0.3489115783239845 3 P49257 1 +Polar cataract 0.7704527993946603 1.7506907846188318 0.0799991876661643 1.0 0.3489115783239845 4 P08670,P50542 2 +Delayed menarche 0.7445340419448051 1.750643247451778 0.0800073808536652 1.0 0.3489115783239845 6 O00429,P02545 2 +Aplasia hypoplasia of the spleen 0.742863867658097 1.743235904366699 0.0812924161863244 1.0 0.3513356223201189 6 P08865,P57076 2 +Abnormal brain lactate level by mrs 0.6696527551859772 1.7429591056980325 0.0813407583731093 1.0 0.3513356223201189 10 O00429,Q9Y6N5 2 +Low alkaline phosphatase 0.7004181600955729 1.7340722370355244 0.0829052668286813 1.0 0.3532617803472122 3 Q96S52,Q92643 2 +Giant platelets 0.6345177664974632 1.7325607743672935 0.0831737662876961 1.0 0.3534313295231523 2 P35579 1 +Congenital nonbullous ichthyosiform erythroderma 0.7660186325983698 1.7318366461475578 0.0833026513453139 1.0 0.3536548458213143 4 P04062 1 +Hypermetric saccades 0.6998207885304595 1.7313004579124225 0.083398189828391 1.0 0.353736512391968 3 Q9NXN4,O14773 2 +Dyschromatopsia 0.7395815509636811 1.7286669697288588 0.0838687161729414 1.0 0.3550463464773685 6 O00429,Q9H061 2 +Death in infancy 0.3805922421889209 1.7206964015190136 0.08530592971615 1.0 0.3558880433258048 61 P18074,Q6PJG6,Q9H267,P50542,Q00059,P07602,Q6P3W7,P50570,P04062,O75381,P40855,O00429,Q9HC21,Q01968 14 +Elevated circulating long chain fatty acid concentration 0.7633263369731835 1.720376642055887 0.0853640000384587 1.0 0.3558880433258048 4 P40855,P50542 2 +Osteoarthritis 0.6804966512979622 1.7174199249093909 0.0859024736892068 1.0 0.3569517428334328 9 Q14108,P04062,Q9NUQ7 3 +Microcytic anemia 0.6644919695082102 1.717010543254912 0.0859772456113696 1.0 0.3569517428334328 10 Q9Y606,Q9UBX3,Q3LXA3 3 +Megalencephaly 0.6956391875746647 1.711883053221413 0.086918222337383 1.0 0.3569517428334328 3 P42345,P49815 2 +Asymmetry of the ears 0.6956391875746608 1.7118830532213962 0.0869182223373861 1.0 0.3569517428334328 3 Q9H2M9,Q9UHX1 2 +Hypoplasia of the vagina 0.63033741415348 1.71121933093432 0.0870406314431555 1.0 0.3569517428334328 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.63033741415348 1.71121933093432 0.0870406314431555 1.0 0.3569517428334328 2 P51809 1 +Gonadoblastoma 0.63033741415348 1.71121933093432 0.0870406314431555 1.0 0.3569517428334328 2 P51809 1 +Ovarian gonadoblastoma 0.63033741415348 1.71121933093432 0.0870406314431555 1.0 0.3569517428334328 2 P51809 1 +Abnormal sex determination 0.63033741415348 1.71121933093432 0.0870406314431555 1.0 0.3569517428334328 2 P51809 1 +Dental crowding 0.4575620356528501 1.7078290322619398 0.0876680704115637 1.0 0.3571433870193406 30 Q09472,P28340,P41227,Q15233,P06753,P02545,Q92643,Q96A33,P27635,O75431,Q01968,Q9NS87 12 +Microvesicular hepatic steatosis 0.6615690754641019 1.7022927099648728 0.0887005107194882 1.0 0.3584887599600211 10 Q00059 1 +Prominent superficial blood vessels 0.6445397538444868 1.6981372527012888 0.0894818599976188 1.0 0.3601023463098619 11 Q13043,P48651,O14802,P02545,O75844,Q9Y487 6 +Emg myopathic abnormalities 0.4797322421894229 1.6957521013954575 0.0899328369867542 1.0 0.361144507852644 26 P53007,P06753,P12235,Q15650,P50570,P46976,P02545,Q8WXH0,O60231,P31483 10 +Abnormality of facial adipose tissue 0.7573946818046032 1.6950959520301052 0.0900572200246783 1.0 0.361144507852644 4 P02545,Q03252,O75844 3 +Caesarian section 0.7573946818045894 1.695095952030049 0.0900572200246889 1.0 0.361144507852644 4 O60313,Q96EY7,P33991 3 +J shaped sella turcica 0.7571206142141484 1.6939268303704107 0.0902791878308544 1.0 0.3614285965318144 4 Q96AX1,O60568 2 +Chorioretinal coloboma 0.7312549659404591 1.6916410508192106 0.0907144344121837 1.0 0.3625449292542101 6 P41227,Q01082,Q10713 3 +Hypokinesia 0.6256595290733542 1.6859004729960403 0.0918149708354241 1.0 0.3649341384991851 12 P06753,P04062,Q9Y3D3,P12235 4 +Increased susceptibility to fractures 0.3789018463307615 1.6785146167234886 0.093246679428312 1.0 0.3686422552545301 59 O15269,O60568,P06753,Q32P28,O75718,Q15650,Q08426,P04062,Q13126,Q14108,P17252,Q01968 12 +Intussusception 0.62287249925351 1.6730340687662124 0.0943205894078416 1.0 0.3718535195208377 2 Q13485 1 +Patent foramen ovale 0.4360081718035506 1.672607013476972 0.0944046853123123 1.0 0.3718535195208377 35 Q96AX1,Q09472,Q86XI2,P25490,Q15233,P20700,Q15650,O95630,P63000,Q9UHB7,Q9Y4A5 11 +Cerebral dysmyelination 0.7050612683029709 1.6639562878585703 0.0961211651341265 1.0 0.3766844645492903 7 P18074,P51659,P07602,P19447 4 +Slender build 0.5885737849255875 1.663183689563668 0.096275671512725 1.0 0.3767432841519134 14 Q15233,P51530,P04350,P06753 4 +Low set posteriorly rotated ears 0.3640471830823389 1.6579775633139051 0.0973219951064368 1.0 0.3791468649692782 73 Q9UHB7,P41227,Q9UQE7,P50542,Q9Y263,P37268,P36507,P04062,O75381,P40855,Q9H6U8,Q10713,Q4J6C6,Q01968,Q15392 15 +Horizontal nystagmus 0.5059156972321348 1.6538315753157649 0.098161738466874 1.0 0.379774003324993 22 P50542,P07602,O00429,P04062,Q9H061 5 +Decreased lymphocyte apoptosis 0.6189907435055262 1.6531410631000336 0.0983021578925775 1.0 0.379774003324993 2 Q14790 1 +Pulmonary embolism 0.6189907435055257 1.6531410631000314 0.098302157892578 1.0 0.379774003324993 2 Q13485 1 +Cutaneous syndactyly of toes 0.7328290632646086 1.6428201421779998 0.100420151485741 1.0 0.3860263866400459 5 Q09472,P27635 2 +Diminished ability to concentrate 0.6806787721311692 1.642209122594226 0.1005466727670394 1.0 0.3861925227406751 3 Q01082 1 +Nasogastric tube feeding in infancy 0.632479234676308 1.6353276137066706 0.1019803878476843 1.0 0.3904055145019527 11 P07602,Q9UHX1,P06753 3 +Abnormal sputum 0.7182511004967821 1.6336328677419043 0.1023359621210908 1.0 0.3910475873712338 6 P57076,Q86Y56,P49815 3 +Progressive external ophthalmoplegia 0.6633516142214527 1.633413882703484 0.1023819792066054 1.0 0.3910475873712338 9 P51530,P12235 2 +Pituitary prolactin cell adenoma 0.6771130681408011 1.6255583386767862 0.1040436439192364 1.0 0.3963404545682665 3 P25490 1 +Decreased adipose tissue 0.5698844493465736 1.622462520579814 0.1047043518233714 1.0 0.3985298645756568 15 P18074,Q03252,P54132,P02545,P19447,O75431,O75844,P41227 8 +Self mutilation 0.5670131039986114 1.605560271496334 0.1083705604423652 1.0 0.40824513796754 15 Q09472,P41227,Q10713,Q9UM00 4 +Misalignment of incisors 0.7241908181543897 1.6050188863193513 0.1084896483986215 1.0 0.40824513796754 5 Q9BSJ2,Q8WXI9 2 +Hemifacial spasm 0.7237601532730531 1.60313210295375 0.1089054917040321 1.0 0.4094775827574154 5 Q10713,P35240 2 +Gastrointestinal inflammation 0.4911906597281833 1.6018934002330616 0.1091791841746521 1.0 0.4096741391071385 23 P08183 1 +Opisthotonus 0.4668200975935779 1.5972037969624908 0.1102202866293406 1.0 0.4108781987960833 26 Q9HA77,P51970,P07602,O60313,Q9H078,P04062 6 +Concave nail 0.6705934124637052 1.5950724015873334 0.1106960462243977 1.0 0.4108781987960833 3 P18074 1 +Tiger tail banding 0.6705934124637052 1.5950724015873334 0.1106960462243977 1.0 0.4108781987960833 3 P18074 1 +Abnormal mean corpuscular hemoglobin concentration 0.6705934124637052 1.5950724015873334 0.1106960462243977 1.0 0.4108781987960833 3 P18074 1 +Increased mean corpuscular hemoglobin concentration 0.6705934124637052 1.5950724015873334 0.1106960462243977 1.0 0.4108781987960833 3 P18074 1 +Low set nipples 0.6705934124637052 1.5950724015873334 0.1106960462243977 1.0 0.4108781987960833 3 P18074 1 +Abnormal placental size 0.7338526794807863 1.5943552207972869 0.1108564959355535 1.0 0.4109073206426942 4 P02545 1 +Abnormal macular morphology 0.4657142027351167 1.58873522461784 0.1121201828249487 1.0 0.4135156464410997 26 P18074,Q9Y4I1,P35221,P35240,P50213,P50897,Q8WWY3,P04062,P19447,Q92620,P51648,Q9UM00 12 +Central scotoma 0.6885918863112902 1.5878906882542665 0.112311059485548 1.0 0.4138903591216223 7 O00429,O60313,Q9H061 3 +Central apnea 0.6869137686614543 1.5801210347358818 0.1140791510092293 1.0 0.4175447119292759 7 P07602 1 +Hypoplastic heart 0.6672582060225776 1.5794573746418028 0.114231186170931 1.0 0.4175447119292759 3 Q9Y4J8 1 +Exercise induced muscle cramps 0.7181235990938517 1.5784196111526672 0.1144692427844873 1.0 0.4178578027943962 5 P53985 1 +Enlarged thorax 0.5388011810241776 1.57726594501995 0.1147343448503206 1.0 0.4181669989984956 17 Q96AX1,Q32P28,P02545,P17252,P41227 5 +Migraine 0.4939379515896347 1.5703308628639516 0.1163381576577586 1.0 0.4221867843170789 22 O00429,Q4G176,P12235,Q9Y6N5 4 +Underdeveloped supraorbital ridges 0.5878373482783973 1.5671428042095423 0.1170813159582253 1.0 0.4221867843170789 13 P36507,O75381,P40855,P50542 4 +Ankyloblepharon 0.6840766112405016 1.566977556265733 0.1171199377580949 1.0 0.4221867843170789 7 P18074,O15111,O75569,P41227 4 +Obstructive sleep apnea 0.587395364958602 1.564677221839012 0.1176586120227924 1.0 0.4221867843170789 13 Q15233,Q09472,P53007,P51530 4 +Myoclonus 0.3491304901757901 1.5625892815404274 0.1181492309902783 1.0 0.4236030114274227 96 Q6PJG6,Q9HA77,Q03252,P35240,P07602,Q9UBX3,P50897,Q9H078,Q96EY7,P04062,Q10713,Q14108,P00374 13 +Abnormality of the intrahepatic bile duct 0.7141726383880216 1.5610778169350463 0.1185053913804785 1.0 0.4236030114274227 5 P50542,Q10713 2 +Subcutaneous hemorrhage 0.4140438550168985 1.559124045512256 0.1189670234854409 1.0 0.4236030114274227 38 P38435,O60568,P51159,P04062,Q13126,Q14108 6 +Very long chain fatty acid accumulation 0.7134096923375075 1.557727266612317 0.1192979140101897 1.0 0.4244552028789253 5 O75381,P50542 2 +Absence of subcutaneous fat 0.6816874718879936 1.5559024575551208 0.1197312889312405 1.0 0.4254955444321346 7 P18074,P02545,P19447,O75844 4 +Abnormality of the foot musculature 0.6617832620524001 1.553797282610099 0.1202327789486834 1.0 0.4254955444321346 3 O14979 1 +Centrocecal scotoma 0.661493465229547 1.55243815434613 0.1205574200352819 1.0 0.4257672189773227 3 O60313 1 +Transient global amnesia 0.7121792676336844 1.552322552108738 0.1205850643911183 1.0 0.4257672189773227 5 P35240,P25490 2 +Cns demyelination 0.5690549416675595 1.5510742700489188 0.1208838864549926 1.0 0.4264974867620591 14 P07602,Q96C36,Q13144,P40855,P51648 5 +Deviated nasal septum 0.7230885299511423 1.548100384894949 0.1215981294478409 1.0 0.4277154234599323 4 Q15233 1 +Cutaneous photosensitivity 0.4547398879220751 1.5437768989574043 0.1226423895458501 1.0 0.4304088705030744 27 P18074,P36551,P37268,P54132,Q15126,Q14108 6 +Diaphragmatic eventration 0.7093608243615567 1.5399369551020423 0.1235757216834181 1.0 0.4323751288485483 5 Q15650 1 +Antenatal onset 0.5826285075506484 1.538064577406458 0.1240328259709482 1.0 0.4336471954761055 13 P20700,O15111,Q9Y285,P27635 4 +Abnormality of dermal melanosomes 0.6582201740719222 1.5370805926310518 0.1242735748513172 1.0 0.4341614868204272 3 P51159 1 +Zonular cataract 0.6280511758595896 1.532516032079868 0.1253951444582872 1.0 0.4370168459648144 10 Q99797,P08670,Q01968,P35240 4 +Mitral stenosis 0.7193345247761225 1.5319440193328295 0.1255362496307124 1.0 0.4370168459648144 4 P02545,P04062 2 +Short nose 0.3464462064832608 1.5317690769844805 0.1255794294348293 1.0 0.4370168459648144 100 Q96AX1,Q9UQE7,O60568,Q9H2M9,Q9UHX1,P83436,Q96C36,P04062,P42892,O95630,Q9Y487,Q9Y4A5,Q15392,Q9Y263,P16435,P42345,P62081,Q9H6U8,P36507,Q969G3,Q9UHB7,Q9UM00,Q86XI2,P20700,Q9Y606,P38435,Q9NVI7 27 +Left ventricular systolic dysfunction 0.6953662182361786 1.531062472480873 0.125753953500856 1.0 0.4370168459648144 6 Q969Y2,P12235,P02545,Q96RR1,O75844 5 +Hypocholesterolemia 0.6564613492959673 1.5284375660124956 0.1264039337748301 1.0 0.4373198783433676 8 P07602,Q15800 2 +Prematurely aged appearance 0.4035966237848943 1.525517365533107 0.1271301055416493 1.0 0.4382173175456087 40 P18074,Q9Y4I1,Q03252,P36507,Q9H2M9,P51159,O14802,P48651,P02545,P19447,Q13126,O75431,O75844,Q9Y487,P41227 15 +Hypoglycemic seizures 0.6750269858845845 1.524994322693612 0.1272605137166518 1.0 0.4382173175456087 7 P53985 1 +Decreased fertility in females 0.6749713206013649 1.5247358112286922 0.1273250057665951 1.0 0.4382173175456087 7 P57076,P54132 2 +Airway obstruction 0.518297781844329 1.5229974580060384 0.1277593413956594 1.0 0.4393859842064371 18 Q96AX1,P16435,P21964,P09601,P54132,P02545,Q86Y56,O75844,P57076,Q96HY6 10 +Alveolar cell carcinoma 0.5936100328456243 1.5225263816316694 0.1278772402348573 1.0 0.4394074133638456 2 Q14790 1 +Abnormal number of permanent teeth 0.7166842193844948 1.520530498731734 0.1283776995245997 1.0 0.4398810162572391 4 Q12959 1 +Hypersomnia 0.5915198566736373 1.511733216004404 0.1306017449992729 1.0 0.443619217659678 2 O00170 1 +High myopia 0.6379203106866524 1.508017032003801 0.1315501679498569 1.0 0.443619217659678 9 Q9Y487,Q92993,P27635 3 +Abnormality of the radioulnar joints 0.6520310633213775 1.50801378102425 0.1315509999769837 1.0 0.443619217659678 3 P16435,Q9Y2D4 2 +Radioulnar dislocation 0.6520310633213775 1.50801378102425 0.1315509999769837 1.0 0.443619217659678 3 P16435,Q9Y2D4 2 +Abnormal thalamic mri signal intensity 0.6702606872391376 1.5028483430485051 0.1328781563789629 1.0 0.4454252588379408 7 Q969Y2,Q96EY7,Q969G3,P35240 4 +Apnea 0.3446163155228787 1.5023538049424696 0.133005759888432 1.0 0.4455061549303176 87 Q9UHB7,Q6PJG6,Q09472,P53007,Q9P0J0,Q9Y263,P50542,P07602,Q15233,P23786,O60313,Q03001,P04062,Q86Y39,Q96A33,P51530,Q10713,O75306 18 +Conical tooth 0.6365855643074007 1.501413356867289 0.1332486813009472 1.0 0.4455061549303176 9 Q9H1A4,Q9Y487,Q12959 3 +Delayed puberty 0.3627394664053523 1.5012042617969108 0.1333027380071194 1.0 0.4455061549303176 60 Q01968,Q9UQE7,Q01082,Q15233,Q9H2M9,P16435,Q9Y606,Q15650,P04062,O00429,P02545,P27635,Q14108,O75844,Q9NVI7,Q8IWS0,Q15800,O60885 18 +Absent earlobe 0.650537634408593 1.5009946517326156 0.1333569448865996 1.0 0.4455061549303176 3 Q09472,O14802 2 +Abnormal auditory evoked potentials 0.6203190163840252 1.4931238385075327 0.1354047735614347 1.0 0.4519341470344216 10 P07602,Q15125,O60313 3 +Facial erythema 0.648389102186449 1.4908931100494411 0.1359895605927086 1.0 0.4527583615962867 3 Q9H1A4 1 +Abnormal middle phalanx morphology of the hand 0.6674592825782422 1.4898218736808844 0.1362710781240654 1.0 0.4531018610809894 7 Q15233,Q9UHX1,Q08AM6,P48651,Q8IWS0 5 +Hyperextensible skin 0.5358614573935299 1.4877580080721544 0.1368147234890453 1.0 0.4543503281484342 16 P04062,Q9UHX1,P25490 3 +Temperature instability 0.6328144027576554 1.4827450997734417 0.1381421472822945 1.0 0.4571585470377426 9 P07602,Q9HC21,Q2TAA5 3 +Neuronal loss in central nervous system 0.5721766429536216 1.4795884576166114 0.1389831086837272 1.0 0.4585937939092886 13 P07602,P04062 2 +Abnormal epiphyseal ossification 0.5230862775447901 1.479323702507127 0.1390538209310943 1.0 0.4585937939092886 17 P50542,Q15125,O75381,P38435,Q96HY6 5 +Burkitt lymphoma 0.5849507315616609 1.4777821409143612 0.1394661000514525 1.0 0.4592079828398679 2 P49327 1 +Central hypoventilation 0.683394177965184 1.477195735227398 0.1396231766746074 1.0 0.4593988978449113 6 P06753,P51608,O75306 3 +Weakness of facial musculature 0.3588322289119132 1.476594364358878 0.1397844033023667 1.0 0.4596031870282073 62 P35240,P34897,Q9UHX1,P50570,O75381,P40855,P50542,O60313,Q96TA2,P51530,P42356,P06753,P48651,O00429,Q969G3,Q86U42,P53007,P12235,P51608 19 +Aspiration pneumonia 0.4587715738458408 1.4751875660848697 0.1401621233655279 1.0 0.460518500299495 25 P06753,P20700,Q96EY7,P04062,Q9UHB7 5 +Thin ribs 0.5558356681439427 1.4747491196895317 0.14028000492762 1.0 0.4605793929493247 14 Q32P28,O14802,P50570,P02545,Q9UBN7,O75431,O75844,Q9Y2D4 8 +Polyhydramnios 0.3648080923208434 1.46784259563408 0.1421469840685598 1.0 0.4647344274625131 55 Q09472,P53007,Q70HW3,P06753,P21964,Q6P3W7,Q08AM6,Q15125,P50570,P04062,P02545,Q9H6U8,P27635,Q9NVI7,Q9UM00 15 +Nonprogressive cerebellar ataxia 0.6421594249426904 1.461582305047746 0.1438557062693912 1.0 0.4693279762596044 3 Q69YN2 1 +Abnormal glomerular filtration rate 0.6417446681127512 1.4596298066843356 0.1443918427977264 1.0 0.4703667270666423 3 Q9H6U8 1 +Pyelonephritis 0.6417446681127512 1.4596298066843356 0.1443918427977264 1.0 0.4703667270666423 3 Q9H6U8 1 +Exercise intolerance 0.4247734846685402 1.4585776231082086 0.1446813962029836 1.0 0.4703667270666423 31 Q8NFF5,Q9Y285,Q9H2D1,P06753,P23786,Q9Y606,P12235,Q9Y5P6,P51530 9 +Scotoma 0.6133363093279449 1.4574910745929692 0.1449808733386612 1.0 0.4703717157588261 10 O00429,O60313,Q9H061 3 +Generalized lipodystrophy 0.7018177552192983 1.4564087327134942 0.1452796629159394 1.0 0.4709905715232833 4 O75431,P02545 2 +Slow saccadic eye movements 0.5977826543036322 1.453348758222397 0.1461269460010132 1.0 0.4730757832826101 11 O60231,P04062,Q8IV08,P34897 4 +Secondary microcephaly 0.3399933193573013 1.4515793037809703 0.1466186168391001 1.0 0.4742482201182336 82 Q09472,Q9UQE7,Q9H2M9,Q9UHX1,P83436,Q96C36,O95630,Q9Y487,P00374,Q6PJG6,Q9HA77,Q9Y263,Q13144,Q9H6U8,Q9HC21,Q9Y5P4,Q86Y39,Q9GZZ9,P50897,Q9BSJ2,P51608,Q13813 22 +Portal fibrosis 0.7006370164243223 1.4513095250154695 0.1466936901746218 1.0 0.4742482201182336 4 P55263 1 +Motor polyneuropathy 0.6119093441353218 1.4502030611160783 0.1470019017024109 1.0 0.4745241424673579 10 P53007,P36551,P08397,P54886,O43819 5 +Pleural effusion 0.5810935048878296 1.444857035236201 0.1484980466877972 1.0 0.4755277054790749 12 Q13043 1 +Diminished movement 0.4886047001883306 1.4445604044067877 0.1485814014194284 1.0 0.4755277054790749 20 P06753,P04062,Q9Y3D3,P12235 4 +Corneal scarring 0.687387219382404 1.4431457143811377 0.1489794279378173 1.0 0.4755277054790749 5 Q09472,Q03001,Q86XI2 3 +Calcific stippling 0.6986232656229464 1.4426108933698072 0.1491301129872169 1.0 0.4755277054790749 4 Q15125 1 +Fasting hyperinsulinemia 0.6869818119234832 1.4413566493329903 0.1494839507209115 1.0 0.4755277054790749 5 P00367,P25490 2 +Narrow nasal ridge 0.6568418092150135 1.440389671443836 0.1497571841788159 1.0 0.4755277054790749 7 O14802,P02545,O75431,O75844,P54886 5 +Wide nasal ridge 0.6977010135314694 1.4386263323803723 0.150256421525966 1.0 0.4761372318485158 4 P27635,O14802 2 +Brittle hair 0.5383584059924091 1.4360185509099137 0.1509970626361898 1.0 0.4774123608328719 15 P18074,P49589,P36507,Q9Y487,P19447,P62266,O75844,Q9NVI7 8 +Premature rupture of membranes 0.6739549409615448 1.43464443965107 0.1513884441895694 1.0 0.4774400185461523 6 P02545,Q9Y487 2 +Accessory oral frenulum 0.6966629233750297 1.4341407260570054 0.1515321079336589 1.0 0.4775682205169562 4 O15111 1 +Unilateral renal agenesis 0.4805872635737734 1.431638754618794 0.1522472324622907 1.0 0.4782578097464944 21 Q2VPK5,Q7LGA3,Q00534,P16435,Q86XL3,Q9UHX1,Q96C36,Q6UVJ0 8 +Elevated pulmonary artery pressure 0.4404372988498082 1.431595570230169 0.1522595981294265 1.0 0.4782578097464944 27 Q96AX1,P51970,P14854,Q08AM6,P04062,P25705,P02545,Q14108,Q9UHB7 9 +Laryngomalacia 0.5261901178657542 1.4288631277384485 0.1530435770641944 1.0 0.4799704180280736 16 Q09472,P16435,P07602,O00192,P21964,O14802,P02545,P27635,Q9UHB7 9 +Impaired distal proprioception 0.6349746312914817 1.427742722631724 0.1533659244107088 1.0 0.4799704180280736 3 O14802 1 +Abnormal echocardiogram 0.6949507021212867 1.4267409092206904 0.1536545892062539 1.0 0.4799704180280736 4 Q969Y2,Q96RR1,P12235 3 +Fetal ultrasound soft marker 0.5032621643142783 1.4264317310387176 0.1537437598730995 1.0 0.4799704180280736 18 Q2TAL8,P50542,P16435,Q15125,O75381,P40855,Q9H6U8,O60826 8 +Persistent ebv viremia 0.5747984472977052 1.4252361554901023 0.1540889483131824 1.0 0.4800782018682216 2 O95394 1 +Decreased specific anti polysaccharide antibody level 0.5747984472977052 1.4252361554901023 0.1540889483131824 1.0 0.4800782018682216 2 P49327 1 +Widely spaced incisors 0.6934860626551418 1.4204098688889806 0.1554883913574187 1.0 0.4828159292250458 4 Q9BSJ2 1 +Abnormal hdl cholesterol concentration 0.6328722144967145 1.4178344483301015 0.1562391041915378 1.0 0.4835276949479102 3 P02545 1 +Diffuse cerebral atrophy 0.5016829187643921 1.4162657336176847 0.1566977164861618 1.0 0.4846234914141736 18 P07602,Q9HA77,Q10713 3 +Abnormality of the mitochondrion 0.3386148641654405 1.414465678910838 0.1572252176531692 1.0 0.4855549929582533 93 Q70HW3,Q969Y2,O43676,Q96EY7,P46976,Q9HA77,Q9P0J0,P50542,P51970,Q08426,P51530,Q4J6C6,O75306,Q9UBX3,O00429,Q86Y39,O75380,P23786,P12235 19 +Neuronal loss in basal ganglia 0.6807025068226915 1.4136337679933633 0.1574694611659275 1.0 0.4857141862709514 5 O43819,O75306 2 +Multifocal seizures 0.6681994037208447 1.4086701577286171 0.1589327230133559 1.0 0.4866713374793782 6 Q6PJG6,Q9HA77 2 +Delirium 0.5715138847417186 1.4082198777825536 0.1590659720006999 1.0 0.4866713374793782 2 P26358 1 +Abnormal aortic valve cusp morphology 0.4323660069196847 1.4079547591518409 0.1591444666994688 1.0 0.4866713374793782 28 Q09472,Q9UQE7,Q01082,P37268,Q13485,Q9UHX1,P61254,P63000,P41227 9 +Elevated circulating follicle stimulating hormone level 0.6305256869772905 1.4067728547167844 0.1594947543257561 1.0 0.4869338778411575 3 P16435,P51809 2 +Muscle abnormality related to mitochondrial dysfunction 0.4060550017010154 1.4056344573644457 0.1598326986159548 1.0 0.4871692247097742 35 O60313,Q9Y606,Q9UBX3,P14854,O43676,P12235,Q86Y39,P51530,O75306 9 +Abnormality of the helix 0.3780263608804128 1.4019151807144918 0.1609405766846119 1.0 0.4897007184053458 46 Q09472,P36551,P50542,Q96N67,Q7LGA3,P36507,O15111,P21964,O00192,P23786,Q96C36,P02545,Q96S52,O75844,P41227 15 +Everted upper lip vermilion 0.648561867294738 1.4017827449815992 0.1609801326250532 1.0 0.4897007184053458 7 P04062 1 +Agenesis of incisor 0.6887645460820271 1.3999936448137071 0.1615152215678827 1.0 0.4901832553743233 4 Q12959,P41227 2 +Bone fracture 0.6478634069917364 1.3985240861473442 0.1619557449192283 1.0 0.4904159591414387 7 Q13126 1 +Pericardial effusion 0.6007111900147775 1.3929471120843118 0.1636357843962761 1.0 0.4942658962473867 10 P04062 1 +Abnormality of the pancreas 0.3363464394826696 1.392171494807661 0.1638704724408597 1.0 0.4942658962473867 79 Q9UJW0,P14174,Q13043,Q9UHX1,P09601,P53985 6 +Metaphyseal striations 0.6754948508332652 1.3906265768251191 0.1643386928778309 1.0 0.4949624637891806 5 Q13126 1 +Poor appetite 0.5403009359888307 1.3847362270468726 0.1661331374256081 1.0 0.4979986853482885 14 Q70HW3 1 +Congenital malformation of the left heart 0.6850673048258262 1.3839997881508153 0.1663585196069525 1.0 0.4979986853482885 4 Q9Y4J8,O14802 2 +Myoclonic spasms 0.644747549601908 1.3839838582787936 0.1663633973764935 1.0 0.4979986853482885 7 Q6PJG6,Q10713,P35240 3 +Aplasia hypoplasia of the 5th finger 0.5295900837773304 1.3838857695691191 0.166393434772325 1.0 0.4979986853482885 15 P63000,Q9UHX1,Q9UQE7,Q969G3 4 +Stroke like episode 0.6831726330805878 1.3758016685710417 0.1688830447366807 1.0 0.5043635638274544 4 P51970 1 +Mild postnatal growth retardation 0.5652433562257368 1.3757177257127111 0.1689090419040531 1.0 0.5043635638274544 2 Q9Y3E5 1 +Tube feeding 0.339706716272538 1.3748356589185182 0.1691824002261059 1.0 0.5047166071095414 75 Q9HA77,P37268,Q15233,P15311,P07602,Q9UHX1,P25490,P06753,Q96EY7,Q15650,O00429,Q4G176,Q96N66,Q9H1A4,Q9NUQ7 15 +Abnormality of pulmonary circulation 0.4172671262358177 1.3733737787979343 0.1696361770397807 1.0 0.5057448982356422 30 Q96AX1,P51970,P14854,Q08AM6,P04062,P25705,P02545,Q14108,O75844,Q9UHB7 10 +Congenital ichthyosiform erythroderma 0.6599351074589811 1.3713435179227875 0.1702678957668089 1.0 0.5059046876887073 6 Q15125,P04062 2 +Parkinsonism with favorable response to dopaminergic medication 0.5959218609767363 1.3684304495145974 0.1711773785098516 1.0 0.5070048208590375 10 P04062 1 +Abnormal circulating proline concentration 0.6223757876951008 1.3683342112526728 0.1712074868001292 1.0 0.5070048208590375 3 P30038 1 +Decreased activity of mitochondrial complex iv 0.5161870227735263 1.3678108020998074 0.1713713056007619 1.0 0.5070048208590375 16 Q70HW3 1 +Increased cerebral lipofuscin 0.6695871019406574 1.364512475502601 0.1724063304926075 1.0 0.5084451324196747 5 P07602 1 +Thenar muscle atrophy 0.6212242600007416 1.3629010523671314 0.1729136970189184 1.0 0.5096172278319808 3 O60568 1 +Male infertility 0.607269603563546 1.3559627442176247 0.175111022142437 1.0 0.5143079434386355 9 P57076,Q8N8E3,P54132 3 +Premature birth 0.3643819592329734 1.355774618776544 0.1751708892773091 1.0 0.5143079434386355 50 Q9UQE7,P50542,P36507,P06753,O43676,Q15650,P04062,O75381,P27635,O75879 10 +Basal ganglia calcification 0.6200371019947117 1.3529054064393415 0.1760858519986619 1.0 0.5159316243046336 8 O00429,O60313,Q9Y3Z3,P19447 4 +Sinus bradycardia 0.6190400462814604 1.3525943886559637 0.1761852460831665 1.0 0.5159316243046336 3 Q99996 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.6774172151309006 1.3508915354603972 0.1767301800922516 1.0 0.5165233507365496 4 P42345,Q08AM6 2 +Clonic seizure 0.5924445104926368 1.3506213048480369 0.1768167725666316 1.0 0.5165233507365496 10 P07602 1 +Thickened nuchal skin fold 0.5486544215752408 1.3474915150843465 0.1778219843183344 1.0 0.5191326947731727 13 Q15125,Q9H6U8,O75381,P50542 4 +Abnormal delivery 0.4678344334125776 1.343640665667878 0.1790646127609787 1.0 0.5221028583395582 21 Q01082,O75718,P06753,O60313,Q96EY7,P50570,P02545,P33991,O75844,Q9Y487 10 +Neck muscle weakness 0.5121298208744265 1.3430170643632464 0.1792664483943276 1.0 0.5222220058314843 16 Q86U42,P53007,P07602,P06753,Q15650,P02545,P46976 7 +Inappropriate antidiuretic hormone secretion 0.5586742311137706 1.3416512167447443 0.1797091113765634 1.0 0.5222867875310576 2 P50336 1 +Prolonged qtc interval 0.6163518742384495 1.3399080821975242 0.1802752301762211 1.0 0.5223474794356008 3 Q99996 1 +Porokeratosis 0.6747056696598093 1.339152780909356 0.1805209407968342 1.0 0.5227196405782907 4 Q15126 1 +Lissencephaly 0.3507100250831326 1.336426206962188 0.1814100051868166 1.0 0.5236717210747708 57 Q9H2M9,Q86XL3,Q96C36,Q6UVJ0,Q6ZXV5,Q9Y5P6,P23258,O00139,Q9Y487,Q15392,Q9H267,Q00534,Q9HC21,Q2VPK5,P42356,Q08AM6,Q96EK5,P20700,P23786,Q9BSJ2 20 +Abnormal pleura morphology 0.4539669940928866 1.334698242936537 0.1819751288879048 1.0 0.5249761652298237 23 P14174,Q13043 2 +Poikiloderma 0.6336924651947735 1.33236030785903 0.1827418184939249 1.0 0.526860118493679 7 P18074,P54132,Q9H1A4,O75431 4 +Abnormal heart valve morphology 0.3315188350883059 1.330924279640988 0.183213927316072 1.0 0.5274274656260226 84 Q09472,Q9UQE7,Q15233,Q9UHX1,Q6ZXV5,P04062,O75431,O75844,Q92993,P37268,P21964,Q13485,P61254,O14802,Q9H6U8,O60826,P54886,P61978,Q01082,P25490,O00192,Q96PU5,P06753,P36507,Q9UBS4,P53701,P41227,O95202,P02545,P63000 30 +Quadriceps muscle weakness 0.6722438004182905 1.3284937479696437 0.1840150476079529 1.0 0.5285587117165848 4 Q96RR1,O95140,P12235 3 +Impaired distal vibration sensation 0.6722438004182756 1.3284937479695795 0.184015047607974 1.0 0.5285587117165848 4 P20700,Q96RR1,P54886 3 +Thoracic hypoplasia 0.4171598575093681 1.3271576172950377 0.1844565490746159 1.0 0.5294314131782627 29 P41227,P16435,O75718,P06753,P42345,Q9UHX1,P04062,Q96A33,Q96HY6,Q9UM00 10 +Atrophy degeneration affecting the brainstem 0.5593284662623152 1.3262285639096691 0.1847640006507753 1.0 0.5294314131782627 12 P20700,O60313,Q5T160,O00429,Q96RR1,Q13217,Q13813,Q9Y4A5 8 +Abnormal temper tantrums 0.6145054677999385 1.3261747681559628 0.184781814883955 1.0 0.5294314131782627 8 P04062 1 +Hypomimic face 0.5592588354332705 1.3258485300896898 0.1848898744468523 1.0 0.5294314131782627 12 P04062,Q9Y263 2 +Limb pain 0.5873867351407095 1.324707833473049 0.1852680740023076 1.0 0.5295331634245981 10 O15269,P36551,P08397,O95140,O75569 5 +Rheumatoid factor positive 0.612007168458772 1.319401451943346 0.1870349366246473 1.0 0.5342538300627634 3 P49327,O95394 2 +Arthropathy 0.659104918785737 1.3181526136737007 0.1874525647056653 1.0 0.5351170504775026 5 O15269 1 +Right ventricular hypertrophy 0.6479364020141719 1.3171053851603178 0.1878033021891627 1.0 0.5357883747378206 6 Q15233,Q969Y2,O95630 3 +Increased serum lactate 0.331179965383596 1.3166564514014003 0.1879538071917865 1.0 0.5358879767165575 101 Q9HA77,Q9P0J0,Q70HW3,P51970,Q9Y606,P14854,Q9UBX3,Q9H078,P22695,P12235,O00429,Q9BW92,Q6P4A7,Q9Y3D3,Q01968,O75306 16 +Perisylvian polymicrogyria 0.6577295325378567 1.312068167042984 0.1894971354973202 1.0 0.5396245209862266 5 P42345,P34897 2 +Ankylosis 0.6576156138606404 1.3115642038083064 0.1896672175734246 1.0 0.5397772993679537 5 P16435,P02545,P48651 3 +Hallux valgus 0.496021880684392 1.3096944058011872 0.1902992368224718 1.0 0.5405804300912864 17 Q15233,P04062 2 +Mottled pigmentation 0.6094739026618194 1.3074438439192833 0.1910620151104494 1.0 0.5417083026743438 3 P02545 1 +Aplasia of the phalanges of the hand 0.6094641196695099 1.3073976654626764 0.1910776898036632 1.0 0.5417083026743438 3 Q08AM6 1 +Undetectable visual evoked potentials 0.6673133467409426 1.3071444071811429 0.1911636719532412 1.0 0.5417083026743438 4 P14854 1 +Recurrent sinopulmonary infections 0.6099973663218793 1.3043836894770784 0.1921027935425452 1.0 0.5430417993068535 8 P57076 1 +Hypoplastic iliac wing 0.666451854192974 1.3034138918893163 0.1924334963217413 1.0 0.5436451486578872 4 Q9UBN7,Q09472 2 +Abnormal male reproductive system physiology 0.3754560325990355 1.302030640625279 0.1929059114211622 1.0 0.544647871710419 42 P35240,P16435,P20700,Q8N8E3,P54132,P04062,Q86Y56,Q969G3,Q9H6U8,Q9H1A4,P57076,Q9UBS4,Q01968 13 +Abnormal midbrain morphology 0.6088022801412369 1.298606275810258 0.1940790831232446 1.0 0.5472935701699283 8 P04062 1 +Muscle stiffness 0.4719756370213802 1.2956512323830394 0.1950956699220112 1.0 0.5498258515248899 19 Q9Y4I1,P07602,P06753,P53985,Q15392 5 +Impaired lymphocyte transformation with phytohemagglutinin 0.5497163332338069 1.2951853701600364 0.1952562903991674 1.0 0.5499442055228071 2 Q10469 1 +Primary adrenal insufficiency 0.5040994804024266 1.2939052181967394 0.1956981618503537 1.0 0.5505198290887378 16 P50542,P35240,P16435,O75381,P40855,O75879 6 +Abnormality of thalamus morphology 0.4928193664609243 1.2895722016156594 0.1971992326089338 1.0 0.5537924036005608 17 P35240,Q969Y2,Q96EY7,Q9Y5P6,Q969G3,Q9UPT5,O43819,O75306 8 +Disproportionate short stature 0.4123167113239541 1.287433906261488 0.1979430926797274 1.0 0.5551507426879712 29 Q32P28,Q9UHX1,Q15125,Q96HY6,Q15392 5 +Bone pain 0.4407555461266442 1.2870587000581415 0.1980738290531756 1.0 0.5551815426182117 24 Q14108,P04062 2 +Abnormal pulmonary thoracic imaging finding 0.4535334787019831 1.286132429739585 0.1983968479125606 1.0 0.5553173552640127 22 P51159,P04062,Q86Y56,P57076,Q01968 5 +Pseudoarthrosis 0.6622930080934252 1.2854048460696426 0.1986508486497453 1.0 0.5553173552640127 4 P02545,Q9NWH9 2 +Pes valgus 0.5790934267791248 1.2821997665015643 0.1997725781156138 1.0 0.5575831861191969 10 P06753,Q9UHX1 2 +Insidious onset 0.660197727897762 1.276331959155727 0.2018381972719571 1.0 0.5587465562744223 4 P04062 1 +Hydrocephalus 0.3269744840160447 1.2758819711867688 0.201997245106974 1.0 0.5587465562744223 82 Q96AX1,P49815,P35240,Q15125,Q9Y5P6,P04062,Q86Y56,P40855,P57076,Q15392,P16435,P21964,O14802,Q00839,O95140,O60826,Q10713,Q01082,O00192,P36507,Q08AM6,P48651,P19447,Q969G3,P53701,P18074,P23786,Q9UBN7 28 +Abnormality of skull ossification 0.4901219909205214 1.272619827721438 0.2031529792116648 1.0 0.5594947589916219 17 O75718,Q32P28,Q08AM6,Q9HC21,P02545,Q9H6U8,O75844 7 +Ridged nail 0.6479538320460712 1.2688204100439406 0.2045051239394402 1.0 0.5594947589916219 5 P18074,P16615 2 +Limb ataxia 0.4509808302056704 1.2680975561561083 0.204763114158847 1.0 0.5594947589916219 22 Q14108,P04062,P14854,Q10713 4 +Abnormal greater sciatic notch morphology 0.6370450811952619 1.267853505995444 0.2048502703191626 1.0 0.5594947589916219 6 Q96HY6 1 +Brain stem compression 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Abnormal central sensory function 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Neuralgia 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Progressive pulmonary function impairment 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Intracranial meningioma 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Decreased circulating follicle stimulating hormone concentration 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Ear pain 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Hypothalamic hypothyroidism 0.6582080421968255 1.2677167325999616 0.204899127169575 1.0 0.5594947589916219 4 P35240 1 +Weak cry 0.5484923472444542 1.2670679948461596 0.2051309783063462 1.0 0.5597334993691706 12 P06753,P53007,Q15650 3 +Long palm 0.6007428352203394 1.2662331882199187 0.2054296087746485 1.0 0.5602186272231005 3 P16435 1 +Epiphyseal stippling 0.5340468712602633 1.2652516985710394 0.2057811152638204 1.0 0.5602976930582284 13 Q15125,P38435,O75381,P50542 4 +Scarring 0.3903640617047821 1.2648027820604173 0.2059420338591935 1.0 0.5602976930582284 35 Q09472,O75695,Q01968,P36551,Q86XI2,O43395,P50213,Q8WWY3,Q15125,Q03001,Q92620,O43837 12 +Elbow flexion contracture 0.4183911396502984 1.2578322216212665 0.2084524400080378 1.0 0.5646331316062602 27 Q7LGA3,O60568,P37268,P16435,P06753,P23786,P48651,P02545,Q8WXH0 9 +Progressive microcephaly 0.3658030098684228 1.2568396055477111 0.2088117213729585 1.0 0.5647941924606629 45 Q6PJG6,Q9Y263,P83436,P50897,Q9H6U8,Q9BSJ2,O95630,Q9HC21,Q9Y487,Q13813 10 +Calcinosis 0.6450926040395948 1.2561635084681997 0.2090566941894946 1.0 0.5647941924606629 5 Q9H1A4,P02545,O75844 3 +Diffuse cerebellar atrophy 0.6338628851868775 1.2534640259207126 0.2100368831904486 1.0 0.5663227714025525 6 P18074,Q9HA77 2 +Abnormal circulating carbohydrate concentration 0.3810467546564896 1.2516713454869406 0.2106896454884617 1.0 0.5675521188172623 38 Q70HW3,O43676 2 +Hypolipoproteinemia 0.6328069450577398 1.2486895470284896 0.2117786455602055 1.0 0.5701543558752107 6 Q15800 1 +Sudden episodic apnea 0.6533678444590532 1.2467617136319662 0.2124848827670793 1.0 0.5711381043629976 4 P53007 1 +Decreased circulating progesterone 0.6322889591854258 1.2463475304702498 0.2126368352309176 1.0 0.5711381043629976 6 P16435,Q13144 2 +Abnormal circulating progesterone level 0.6322889591854258 1.2463475304702498 0.2126368352309176 1.0 0.5711381043629976 6 P16435,Q13144 2 +Abnormality of the musculature of the upper limbs 0.3315215380392546 1.244054226181741 0.2134796061123918 1.0 0.5724068559497099 73 O60568,P62854,P50570,P46976,Q9Y5P6,Q8WXH0,Q9Y487,Q7Z392,P07602,O60313,P61254,P62081,O95140,Q06210,P41250,P36551,Q96IJ6,P06753,P08397,O00429,Q96RR1,P62899,P12235,P02545,P31483,O14979 26 +Neoplasm of the tracheobronchial system 0.5937873357228087 1.2334145710232582 0.2174211314368985 1.0 0.5803398650595979 3 Q14790,Q9UPY3 2 +Aplasia hypoplasia of the vagina 0.593488649940252 1.232005652899696 0.2179469724869549 1.0 0.5806908991089214 3 P51809,Q8IY37 2 +Respiratory arrest 0.5941662172774869 1.227850015432531 0.2195032762324591 1.0 0.5822666407902766 8 P49748,P53007,Q14203,P23786,Q96L58,Q9Y2D4 6 +Abnormality of circulating leptin level 0.6486152032579546 1.2261915219206925 0.2201266109664552 1.0 0.5822666407902766 4 P02545,P51608 2 +Narrow forehead 0.3523364468426969 1.2261536294880278 0.2201408674313547 1.0 0.5822666407902766 50 Q2VPK5,Q7LGA3,Q96N67,P36507,P20700,Q9UM00,Q9UHX1,P83436,Q13555,Q96C36,Q5T160,Q96A33,Q9BSJ2,Q9UHB7,P41227 15 +Metatarsus adductus 0.4930198006912878 1.2260998369447822 0.2201611072143066 1.0 0.5822666407902766 16 Q03252,P50542,Q08AM6,Q15392 4 +Epistaxis 0.5268720558085153 1.2248432426594091 0.2206342886146475 1.0 0.5824986694840466 13 P49257,P35579,P04062,P38435,P12814 5 +Ichthyosis 0.3834046342950459 1.2240734995680094 0.220924501958228 1.0 0.5825972645496843 36 P18074,P51648,P50542,P36507,Q15125,P04062,O75381,P40855,Q15800 9 +Profound global developmental delay 0.5403057780719085 1.2223660856309018 0.2215692183803166 1.0 0.5834179523790722 12 P50542,P37268,O60313,O75381,P40855 5 +Symptomatic seizures 0.592702106143902 1.2207737872107614 0.2221716811938883 1.0 0.5842245683578368 8 P53985 1 +Inappropriate crying 0.5797018238247151 1.218820820466636 0.222912207306299 1.0 0.5855076448000013 9 P07602,Q96S52,Q9H6U8,Q9NS87 4 +Glomerulopathy 0.5916237235937422 1.2155622818976164 0.2241517097294383 1.0 0.5875189114358672 8 Q14108,Q03252,Q01968 3 +Upper airway obstruction 0.6358916963604073 1.2154753420326347 0.2241848477847388 1.0 0.5875189114358672 5 P16435,P02545,Q96HY6 3 +Cessation of head growth 0.6078617615608471 1.2116716863984869 0.2256380814805703 1.0 0.5895256692243049 7 Q13144,Q9Y263 2 +Primitive reflex 0.622855921607194 1.2037105439714035 0.2287014754875362 1.0 0.5933184333297248 6 Q14203,P54886,P26358 3 +Increased serum pyruvate 0.3920677825420489 1.2025169178886357 0.2291633154504904 1.0 0.5941535852723341 32 Q70HW3,O43676 2 +Abnormality of the shoulder girdle musculature 0.3892225651372121 1.2011275150439178 0.2297017412461066 1.0 0.5945474768429438 33 P07602,P06753,O60313,P12235,O00429,Q9Y487,O14979 7 +Cirrhosis 0.3696725493881255 1.2000781388275443 0.2301089949248438 1.0 0.5946406357143679 40 Q14108,P04062,Q00059,Q13043 4 +Protruding tongue 0.5084122453597338 1.199401309645314 0.2303719386083522 1.0 0.5948431609765378 14 P42356,P20700,O15111,P67870,P83436,Q10713 6 +Hoarse cry 0.5312033442818819 1.199215953305374 0.2304439855724465 1.0 0.5948431609765378 2 Q69YQ0 1 +Abnormal larynx morphology 0.3914198318870693 1.1969431608276202 0.2313287097648093 1.0 0.5963708177132608 32 Q09472,Q01082,P16435,Q13485,P07602,Q9UHX1,P21964,O00192,O14802,P02545,P27635,Q9UHB7,Q96HY6 13 +Abnormal circulating follicle stimulating hormone concentration 0.6043402068265025 1.195228162084632 0.2319978983235233 1.0 0.597412913137557 7 P16435,P35240 2 +Abnormality of facial musculature 0.3209461433304612 1.194466687144954 0.2322954642304302 1.0 0.597412913137557 82 P34897,P35240,Q9UHX1,Q13555,P50570,P04062,O75381,P40855,Q9Y263,P50542,O60313,Q96TA2,P51530,P42356,P25490,P06753,P48651,O00429,Q969G3,Q86U42,P53007,P12235,P51608 23 +Dermal atrophy 0.4008713662206088 1.193503876276092 0.2326720949681764 1.0 0.597412913137557 29 P18074,P28340,Q03001,P02545,Q9H1A4,P17252,O75844,P53701,Q15392 9 +Blistering by anatomical location 0.5300089578978862 1.193031548437946 0.2328570176961961 1.0 0.597412913137557 2 Q9H4L7 1 +Acral blistering 0.5300089578978862 1.193031548437946 0.2328570176961961 1.0 0.597412913137557 2 Q9H4L7 1 +Abnormality of the fetal cardiovascular system 0.6306662678469092 1.1923815499739232 0.2331116712982583 1.0 0.5975908987561069 5 P16435,O60826,Q2TAL8 3 +Cutaneous syndactyly 0.5610642089701894 1.189793348222056 0.2341276246543979 1.0 0.598684869221064 10 Q09472,P27635,O15111 3 +Shoulder dislocation 0.6400386008630108 1.1890931086417298 0.2344030298889201 1.0 0.5987286206969884 4 Q96PU5 1 +Abnormally large globe 0.6023949340213994 1.1861475262739722 0.2355640445516553 1.0 0.6007775643944837 7 Q01968,Q86XI2,P30533 3 +Cranial asymmetry 0.6189511500881024 1.1860717570791133 0.2355939629139714 1.0 0.6007775643944837 6 P40855,O14802 2 +Numerous pigmented freckles 0.6388864720974409 1.1841123956270714 0.236368573944061 1.0 0.6024215001674915 4 P18074 1 +Decreased circulating antibody level 0.354651250806877 1.1817272103302328 0.2373139579540866 1.0 0.6038350763310348 47 Q9UJW0,P09601 2 +Chronic constipation 0.3993923020328193 1.18136644028914 0.2374571838319275 1.0 0.603868076930782 29 Q09472,Q7LGA3,Q03252,P20700,P04062,P51608 6 +Recurrent bronchopulmonary infections 0.6273590913284474 1.177772870959742 0.2388871667838299 1.0 0.6052013187910326 5 P18074,Q96AX1 2 +Abnormal gallbladder morphology 0.3781172955870259 1.1759747991181888 0.2396049465990848 1.0 0.6060057460083782 36 P07602,P04062,Q13043 3 +Heterophoria 0.5802869059232054 1.1697833398966957 0.2420881697871828 1.0 0.6107825824986359 3 Q7Z392 1 +Abnormal morphology of myocardial trabeculae 0.624855896973906 1.1667201245454757 0.2433234129797257 1.0 0.6120712656397224 5 Q15233 1 +Abnormality of the umbilical cord 0.5807419399652474 1.1630045624375234 0.2448276513252589 1.0 0.6144099940625485 8 P16435,P02545,Q2TAL8,O75844 4 +Bilateral cryptorchidism 0.5972658308405254 1.162215469731669 0.2451479524101079 1.0 0.6144818559695353 7 Q15233,P27635,P37268 3 +Abnormal venous morphology 0.3916127605079765 1.15857299317143 0.2466302825621387 1.0 0.617708260377134 30 P04062,P57076,Q13043 3 +Muscle fiber atrophy 0.4461667998803272 1.157180671005476 0.2471985530696123 1.0 0.618797241917237 20 P53007,Q06210,P06753,P23786,Q15650,P02545,Q8WXH0,Q7Z392 8 +Cytochrome c oxidase negative muscle fibers 0.5958581515671887 1.155650498565756 0.2478241434995058 1.0 0.6200284561595841 7 P14854,P12235 2 +Focal cortical dysplasia 0.5768640120193254 1.1536721880943153 0.248634590343636 1.0 0.6214762275629889 3 P42345 1 +Inappropriate behavior 0.4705268514974623 1.1494622238397874 0.250365435000464 1.0 0.6226899982093087 17 P07602,Q9H6U8,Q96S52,P51608,Q9NS87 5 +Prenatal maternal abnormality 0.4898624726662123 1.1471104563939192 0.2513359728388453 1.0 0.6244338532051914 15 Q09472,Q01082,P16435,P02545,Q86Y56,P57076 6 +Polyneuropathy 0.4698686048578119 1.1453280306806368 0.2520732986614726 1.0 0.6252604668777888 17 P07602,O60313,P35240 3 +Feeding difficulties 0.2567583821861844 1.1427187438122963 0.2531553849573622 1.0 0.6270262166782482 358 P83436,Q96C36,O43676,P04062,P00374,Q9Y4A5,Q15392,P07602,P21964,P42345,Q96F07,Q8NFF5,P42356,Q2TAL8,P51571,P22695,Q4G176,Q969G3,Q96S52,Q9GZZ9,Q9NS87,P53007,Q7LGA3,Q86XI2,P30622,P14854,P02545,Q96N66,P61960,P53985,P51608,Q9Y3D3,Q15233,Q9UHX1,Q03001,O75381,Q9Y487,Q12959,Q6PJG6,Q9HA77,Q9Y263,P37268,P15311,Q9BXJ9,Q10713,P06753,Q9H078,Q15650,O00429,Q9NUQ7,Q96EY7,P50542,O60313,Q9H1A4,Q8IWS0,Q4J6C6,O75306,O43681,P25490,P36507,P53701,P18074,P27635,P63000,Q01968,Q09472,Q9Y285,Q9UQE7,Q969Y2,Q6P3W7,P40855,Q7Z392,Q2TAA5,Q9HC21,Q86Y39,Q9UHB7,Q9UM00,O75380,P20700,P23786,P54132,Q96A33,Q9NVI7 83 +Disproportionate short limb short stature 0.4268143665631632 1.1386364277270449 0.2548548281682969 1.0 0.6284845778672008 23 O75718,Q32P28,P42345,Q15125,Q9H6U8,Q15392 6 +Aplasia hypoplasia involving the skeleton 0.2532065195949419 1.1385045876408744 0.2549098443286592 1.0 0.6284845778672008 329 Q09472,Q03252,Q9UQE7,Q32P28,Q86XL3,Q9UHX1,P83436,Q13555,Q6P3W7,Q9H2M9,Q15125,Q9NR45,P04062,O75381,P40855,O95630,O75431,Q96HY6,Q15392,Q9Y4A5,Q6PJG6,Q9H267,P28340,Q9Y263,P50542,P37268,P16435,O15111,P21964,P42345,P61254,P62081,Q00839,Q9H6U8,P51530,Q9H1A4,Q9HC21,Q9Y5P4,Q8IWS0,Q9NWH9,Q2VPK5,P42356,P25490,P06753,Q96PU5,O75718,P51571,Q08AM6,P48651,Q15650,Q969G3,Q96EK5,P17252,P62899,Q96S52,P53701,Q9UHB7,P41227,P18074,Q9UM00,Q9NS87,P53007,Q7LGA3,Q86XI2,P51608,P33992,Q9Y606,P54132,P02545,Q96A33,P27635,P38435,Q9NVI7,P63000,Q01968,Q8WXI9 76 +Abnormal atrioventricular valve morphology 0.368906189392483 1.1382778507044808 0.2550044797500237 1.0 0.6284845778672008 38 P25490,Q15233,Q13485,P21964,O00192,P06753,P04062,P02545,Q9H6U8,O75431,O75844,Q9UBS4,P53701 13 +Bulbous nose 0.3441362671378594 1.1379641405199536 0.2551354563300414 1.0 0.6284845778672008 50 Q9UQE7,Q96N67,Q6P3W7,Q96C36,P42892,Q13409,O75431,Q92993,Q9Y4A5,P16435,P21964,Q2TAL8,Q01082,P25490,Q96EK5,Q9NS87,P23786,Q96A33,Q9BSJ2 19 +Lactic acidosis 0.3183135773116654 1.1362427808168307 0.25585497057603 1.0 0.6299222748754515 90 Q70HW3,P51970,Q4J6C6,Q969Y2,Q9Y606,P14854,P12235,Q9Y6N5,O43676,Q3LXA3,O00429,Q86Y39,Q10713,O75879,Q9HC21,Q6P4A7,Q9Y3D3,O75306 18 +Decreased pulmonary function 0.617349149091635 1.1336024790825805 0.2569613326775815 1.0 0.632310370643985 5 P35240 1 +Abnormal right ventricle morphology 0.5238959477883792 1.1328431642588854 0.257280121266136 1.0 0.6327589613739026 12 Q15233,P06753,Q969Y2,Q9H6U8,O95630,Q7Z392 6 +Retrognathia 0.3168927232673785 1.1324515642239228 0.2574446367385876 1.0 0.6328278557370585 84 P18074,Q2VPK5,P41227,Q09472,P53007,P37268,Q9UHX1,Q15650,Q15125,P04062,Q9UPT5,Q9H6U8,P27635,Q9Y3B2,P53701,Q4J6C6,Q15392 17 +Adrenal overactivity 0.6166880888934732 1.130688364082822 0.2581862805510357 1.0 0.633978599912395 5 P17252 1 +Abdominal aortic aneurysm 0.571784900559716 1.1297872376338174 0.2585658871703611 1.0 0.6345746177457883 3 Q13485 1 +Abnormality of subcutaneous fat tissue 0.4957347534377631 1.1257539552167335 0.2602696787568674 1.0 0.6367336309851386 14 P02545,O75431,P17252,O75844,Q9Y487,P41227 6 +Upslanted palpebral fissure 0.3174889044940865 1.118762122677005 0.2632416347234649 1.0 0.6416341843207064 97 Q09472,Q15233,Q86XL3,Q9UHX1,P83436,Q96C36,Q15125,Q6UVJ0,O75381,P40855,P42695,Q13409,Q9Y4A5,P50542,Q00534,P21964,Q00839,Q9Y5P4,Q2VPK5,Q2TAL8,Q01082,Q08AM6,Q9UM00,Q7LGA3,P20700,Q9BSJ2,Q9NVI7,P51608,Q01968,Q8WXI9 30 +Low frustration tolerance 0.5470413910802809 1.118033262023659 0.2635527876510357 1.0 0.6417178169906521 10 P04062 1 +Progressive extrapyramidal movement disorder 0.6132695756126846 1.115625455466294 0.2645824912467929 1.0 0.6425376791095505 5 P54136,Q9BPX6,Q9H078,Q6P4I2 4 +Malnutrition 0.6129978646211441 1.1144287286701444 0.2650953043168336 1.0 0.6434104500037988 5 Q12959 1 +Reduced factor xiii activity 0.5138847417139519 1.1097008790231122 0.2671279439959142 1.0 0.6463371173562418 2 Q02750 1 +Amegakaryocytic thrombocytopenia 0.5138847417139519 1.1097008790231122 0.2671279439959142 1.0 0.6463371173562418 2 Q02750 1 +Abnormality of bone mineral density 0.2976756043578983 1.1071463720635173 0.2682306492438169 1.0 0.6472941721364802 141 O60568,Q32P28,Q15125,P04062,Q14108,Q9Y487,Q96HY6,Q15392,Q13043,P07602,Q08426,Q13126,Q9H1A4,Q9HC21,O75718,P17252,P18074,P12235,P27635,Q01968,Q9NUQ7 21 +Myopathy 0.3164968223229768 1.1068559536040588 0.2683562120030878 1.0 0.6472941721364802 93 Q03252,Q3LXA3,O43676,P50570,P46976,Q7Z392,O60313,Q13126,P51530,O75306,P06753,Q15650,O00429,Q86Y39,P17252,Q86U42,P53007,Q9Y606,P12235,P31483,O14979 21 +Abnormal number of incisors 0.5838125269965618 1.0995459943539727 0.2715299835252649 1.0 0.6529113089331577 7 Q12959,P41227 2 +Deep plantar creases 0.5835066007217223 1.0981230836701872 0.2721507468084549 1.0 0.6540647289808177 7 Q09472,P42345,Q9Y487,P61978 4 +Generalized hyperreflexia 0.6187908309394266 1.0974027909360582 0.2724653539287094 1.0 0.6541426104678907 4 P18074 1 +Severe muscular hypotonia 0.3978550073051586 1.095779539667524 0.2731752644605096 1.0 0.6551684045726449 27 Q9HA77,P53007,P50542,P06753,Q15650,O75381,P40855 7 +Decreased facial expression 0.3839124909380848 1.0941467831916347 0.2738906069698466 1.0 0.6562050924610897 30 Q86U42,Q9Y263,P06753,P12235,Q9Y5P6,P04062,Q6P1N0,P51530,Q9Y5P4,Q9GZZ9 10 +Suicidal ideation 0.5636680813528356 1.0916824251459782 0.2749727126820689 1.0 0.6584573842944584 3 Q01082 1 +Psychomotor deterioration 0.5658083145486414 1.0910280167947537 0.275260554788562 1.0 0.6588063665460886 8 P07602,P50897 2 +Secundum atrial septal defect 0.6164470644979709 1.0873159600652331 0.2768971975412984 1.0 0.6622582268044126 4 Q15650,P34897 2 +Muscle hypertrophy of the lower extremities 0.5649937818948023 1.0871093110052914 0.2769885034024495 1.0 0.6622582268044126 8 P50570,P02545,Q9Y5P6,P53007 4 +Acquired abnormal hair pattern 0.6065356833435924 1.08599092702407 0.2774830063563904 1.0 0.6630985657052711 5 P02545,P54132 2 +Mandibular aplasia 0.6160503126866541 1.0856091298305708 0.2776519588137811 1.0 0.6631604745289486 4 O15111 1 +Wormian bones 0.4304681558913686 1.0852333741812987 0.2778183061625097 1.0 0.6632161006021601 21 O75718,Q32P28,P02545,Q9Y487,Q9UHB7 5 +Diplopia 0.4353248854834664 1.0837645623032603 0.2784692014391305 1.0 0.6637445850240665 20 P18074,P04062,P53007,P35240 4 +Deformed sella turcica 0.6048606717113808 1.0786280145210063 0.2807535875829239 1.0 0.6663128787084553 5 Q96AX1,O60568 2 +Coxa vara 0.5007120985636521 1.077747978162518 0.2811462409472156 1.0 0.6663568369280632 13 Q9Y487,P50542,Q96HY6,Q9NUQ7 4 +Cupped ear 0.5131225609207608 1.0742103379578123 0.2827284200112605 1.0 0.6687392628429611 12 Q2TAL8,P42892,Q9UHB7,Q15392 4 +Round face 0.4116178470986026 1.071915408300816 0.2837580287947598 1.0 0.6701488647440177 24 Q9UHB7,O75718,Q32P28,P02545,Q92993,Q9NS87 6 +Reduced systolic function 0.612270195573051 1.069357217520134 0.2849087373784111 1.0 0.672181631799651 4 Q3LXA3 1 +Nasal speech 0.3553162792609937 1.0623563144788195 0.2880739579657754 1.0 0.6779916330799154 40 P53007,Q15233,P06753,Q13409,Q9Y487,Q12959 6 +Rhinitis 0.5748384951271301 1.057857402331029 0.2901204581332401 1.0 0.6803229357135566 7 P57076,P54132 2 +Hypoplasia of the musculature 0.5900968915214708 1.0561175660678337 0.2909145059463305 1.0 0.6813519954320519 6 P06753,Q9Y487 2 +Abnormal aortic valve morphology 0.346001845294212 1.0559299818906411 0.2910002051241291 1.0 0.6813519954320519 45 Q09472,Q9UQE7,Q01082,P37268,P36507,P21964,Q9UHX1,P61254,P04062,P02545,O75844,P63000,P41227 13 +Progressive distal muscle weakness 0.5031352642579943 1.0543790909698023 0.2917093912020063 1.0 0.6823232783110502 2 P55084 1 +Equinus calcaneus 0.5031352642579943 1.0543790909698023 0.2917093912020063 1.0 0.6823232783110502 2 P55084 1 +Immunodeficiency 0.3176418908562443 1.047676674393057 0.2947875978880585 1.0 0.6864283460432061 71 Q9UJW0,P09601,Q13043 3 +Nasogastric tube feeding 0.3830339249385862 1.0473350999909106 0.2949450529158901 1.0 0.6864283460432061 29 Q9HA77,Q15233,P15311,Q96EY7,Q4G176,Q96N66,Q9NUQ7 7 +Progressive muscle weakness 0.4817669244559773 1.0448295222546895 0.2961017677090729 1.0 0.6884291851049459 14 P50542,P06753,Q9Y606,O75381,P40855 5 +Status epilepticus 0.3315232584922736 1.0408616019952714 0.2979397848777763 1.0 0.6913088680754413 52 Q05682,Q03252,P49589,P49815,P42892,Q9Y487,Q15392,Q9HA77,P50542,P51970,P07602,Q96F07,O00429,Q96RR1,P30038,Q96S52,Q9NZJ7,Q9GZZ9,P53701,P67870,P51608 21 +Abnormal bone structure 0.2632048743032251 1.04022568823208 0.298235059566627 1.0 0.6913088680754413 186 O60568,Q32P28,Q86XL3,Q15125,P04062,O75381,P40855,Q14108,Q9Y487,Q96HY6,Q15392,P50542,Q00534,Q13043,P07602,Q08426,Q13126,Q9H6U8,Q9H1A4,Q9HC21,O75718,P17252,P18074,P12235,P27635,P38435,Q01968,Q9NUQ7 28 +Abnormal cry 0.4708902211182895 1.0343420336791715 0.3009762929095105 1.0 0.6948835129125951 15 P53007,P06753,O60313,Q15650,P51608 5 +Abnormality of the posterior pituitary 0.5304309059898351 1.0333308318897128 0.3014491033548885 1.0 0.6952124287480256 10 P42356,Q9UHX1,P35240 3 +Ectropion 0.4795665751642019 1.0321135457947956 0.302018928892299 1.0 0.6952124287480256 14 P18074,P04062,P19447,O14802 4 +Capillary hemangioma 0.5301753286992168 1.0320311535704911 0.3020575235184197 1.0 0.6952124287480256 10 P16435,Q09472,Q9UHX1 3 +Stuttering 0.5503776521390635 1.0295135739234516 0.3032384045695739 1.0 0.6964581362805807 3 Q12873 1 +Abnormality of the cerebrospinal fluid 0.2899910305219713 1.02872014830265 0.3036111992047048 1.0 0.69679841106208 147 Q96AX1,O43678,Q03252,P49815,P35240,O43676,Q15125,Q9Y5P6,P04062,Q86Y56,P40855,P57076,Q15392,Q9P0J0,P51970,P07602,P16435,P21964,O14802,Q00839,Q5T160,O95140,Q96RP9,O96000,O60826,Q9HC21,Q10713,Q02218,O75306,O43681,Q01082,O00192,P36507,Q08AM6,P48651,P19447,Q969G3,P30038,Q9Y3Z3,Q86Y39,Q9NZJ7,P53701,P18074,O75380,P20700,P23786,Q9Y6M9,P14854,O95202,Q9UBN7,P51608,O43819 52 +Flat face 0.3851353672766845 1.0284044461847883 0.3037596179371147 1.0 0.69679841106208 28 Q09472,Q9UQE7,O60568,P50542,Q15125,O75381,P40855,Q9Y487,Q92993,Q9UM00 10 +Pseudobulbar paralysis 0.5520700186365738 1.02506710207635 0.3053315269478425 1.0 0.6993660864279633 8 P54136,P42356,P20700,Q15233,P08397,P54886 6 +Aplasia hypoplasia of the phalanges of the toes 0.5490396982563437 1.0232735831853923 0.306178510299228 1.0 0.7005190032313628 3 Q08AM6 1 +Pseudobulbar signs 0.5161926444185578 1.022825495360589 0.3063903611977872 1.0 0.7005190032313628 11 P54136,P42356,P20700,Q15233,Q14203,P08397,P26358,P54886 8 +Wide cranial sutures 0.5283439750043415 1.022722039290339 0.3064392878673865 1.0 0.7005190032313628 10 O75718,Q08AM6,O14802,P02545,O75844 5 +Multiple gastric polyps 0.5487534439349248 1.0219390350827458 0.3068097557871061 1.0 0.7010202207141567 3 Q13485 1 +Supranuclear gaze palsy 0.4301901540155811 1.0181984045841614 0.3085836775026374 1.0 0.7036938575226065 19 P04062 1 +Pain 0.2627317664419237 1.0165144154989407 0.309384486394999 1.0 0.7037813929966711 190 Q03252,Q70HW3,P35240,Q8N1F7,P50570,P04062,P42892,Q14108,Q7Z392,Q15800,Q96HY6,Q9HA77,Q13043,P07602,O60313,Q08426,Q9H6U8,Q15165,P51530,Q9NWH9,P14174,P36551,O00429,Q14566,Q9UBS4,P18074,P20700,P23786,P14854,P12235,Q9P2R3,Q9NUQ7 32 +Abnormal cortical gyration 0.2924499122083801 1.0114469227419205 0.3118025727110556 1.0 0.7052751547424918 140 Q03252,P34897,Q9H2M9,Q86XL3,Q96C36,Q6UVJ0,Q9Y5P6,O75381,Q6ZXV5,P40855,Q13409,P23258,O00139,Q9Y487,Q92993,Q9Y4A5,Q15392,Q9H267,Q9Y263,P50542,Q00534,P37268,P15311,P42345,Q9HC21,Q10713,Q2VPK5,P42356,Q08AM6,Q969G3,Q9UPT5,Q96EK5,P30622,P20700,P23786,Q96N66,Q9BSJ2,P51608,P63000,Q9NUQ7 40 +Congenital hip dislocation 0.4091328411391852 1.011304148668464 0.3118708810522708 1.0 0.7052751547424918 23 P53007,Q9UHX1,Q9Y487 3 +Proximal muscle weakness in upper limbs 0.4887691264042367 1.0109052924024535 0.3120617607521381 1.0 0.7052751547424918 13 P36551,P08397,P50570,P02545,Q9Y5P6,Q8WXH0 6 +Resting tremor 0.4483452127299347 1.010493640003486 0.3122588449905379 1.0 0.7052751547424918 17 P07602,P04062 2 +Thoracic scoliosis 0.5008503674971296 1.0076573760183969 0.3136189741303317 1.0 0.7068242897755069 12 P50542,P06753,Q9UHX1,Q96C36,P02545 5 +Macular purpura 0.4751781826407796 1.0067858404087051 0.3140377005155934 1.0 0.7071714211758822 14 P04062,P51159 2 +Abnormal sternal ossification 0.5969054363258062 1.0035208792283383 0.3156096080730648 1.0 0.7092419500856658 4 Q08AM6 1 +Visual acuity test abnormality 0.5875817237757813 1.0029195215129223 0.3158996928516102 1.0 0.7095498915019695 5 P35240 1 +Occipital encephalocele 0.5963508977037967 1.0011523946212666 0.316753137680319 1.0 0.7103869748611327 4 Q6ZXV5,Q10713 2 +Abnormality of the phalanges of the hallux 0.5960832615860916 1.0000095087696703 0.3173059061970193 1.0 0.7103869748611327 4 Q09472 1 +Osteolytic defects of the distal phalanges of the hand 0.5956092023382149 0.997985476669188 0.3182864011929041 1.0 0.7107128264508963 4 O75431,P02545 2 +Recurrent respiratory infections 0.2988615800715286 0.9977298303939282 0.3184103840678411 1.0 0.7107128264508963 130 Q9UJW0,Q09472,P04062,P57076,Q9Y487,P50542,P07602,P13051,P09601,P14174,P06753,Q15650,P18074,Q9Y4I1,P53007,P20700,P26038,P63000,Q01968 19 +Abnormality of the brainstem white matter 0.5425942581089348 0.993268855485622 0.3205789508937333 1.0 0.7138582563955966 3 Q10713 1 +Lewy bodies 0.5341577430124231 0.9932340100984308 0.3205959278211194 1.0 0.7138582563955966 9 P04062 1 +Focal tonic seizure 0.4902956106300475 0.9886554507187972 0.3228317461527552 1.0 0.7174726630700735 2 Q00577 1 +Localized hirsutism 0.5744867929712535 0.9862845638576035 0.3239934923574155 1.0 0.7186764739564488 6 P36551,P27635 2 +Joint swelling 0.5437144676893156 0.9851186873949762 0.3245657751203019 1.0 0.7189139672516578 8 P14174 1 +Eeg with polyspike wave complexes 0.5740337784743056 0.984264955361832 0.3249852556119126 1.0 0.7193778443008149 6 Q14108 1 +Abnormality of hand joint mobility 0.5829016931497593 0.9825055262688892 0.3258508617797553 1.0 0.7201592256964668 5 Q9Y263,P25490 2 +Oculomotor nerve palsy 0.5736145255488408 0.9823962538425708 0.3259046711628963 1.0 0.7201592256964668 6 Q969G3,P35240 2 +Abnormal circulating cholesterol concentration 0.3662380767967054 0.9809686405317012 0.3266082062470925 1.0 0.7204083365983405 32 P37268,P07602,Q8N511,Q15125,Q15800,Q15392 6 +Bilateral talipes equinovarus 0.5732794399401391 0.9809029779680056 0.3266405888092449 1.0 0.7204083365983405 6 Q2VPK5,Q15392 2 +Increased sensitivity to ionizing radiation 0.5729216749772722 0.9793089040764394 0.3274273722419258 1.0 0.7204951341976621 6 Q969G3,P35240 2 +Uric acid nephrolithiasis 0.4876082412660569 0.9749596331891862 0.3295802838045276 1.0 0.7223774336601927 2 P07741 1 +Macroscopic hematuria 0.4876082412660569 0.9749596331891862 0.3295802838045276 1.0 0.7223774336601927 2 P07741 1 +Microglossia 0.5900719922630785 0.9743776268872304 0.3298690739988412 1.0 0.7223774336601927 4 Q03252 1 +Generalized myoclonic seizure 0.3460625358210254 0.9740171556786392 0.3300480211391716 1.0 0.7223882648553479 40 Q6PJG6,Q9HA77,P07602,P04062,Q96N66 5 +Secondary growth hormone deficiency 0.580787413515267 0.9732982313643286 0.3304051012230187 1.0 0.7223882648553479 5 Q969G3,P35240 2 +Rotary nystagmus 0.589184344188833 0.9705991714165476 0.3317479187470371 1.0 0.7234164399394468 4 Q6ZMI0,O94905,Q9Y4R8 3 +Areflexia of lower limbs 0.4325063555825904 0.9702458940332152 0.3319239395590081 1.0 0.7234599829786373 18 O60313,P55072,P12235,P50570,P49959,P04792,O95140,Q96RR1,Q13217,P54886 10 +Bradycardia 0.4683709522265634 0.9675982718169188 0.3332450407024547 1.0 0.7256571201017287 14 Q6PJG6,Q03001,Q99996 3 +Abnormality of the gallbladder 0.3400762800406761 0.9671224273430784 0.3334828351629053 1.0 0.7258340017911874 43 P07602,P04062,Q13043 3 +Brain imaging abnormality 0.3410465457024355 0.9640781481850408 0.3350067473061431 1.0 0.7284668295081048 42 Q96AX1,Q09472,P35240,P07602,P08397,O14802,Q9Y6N5,O00429,Q969G3,Q9NZJ7,O43819,O75306 12 +Macrocytic anemia 0.3567560862033068 0.9637539045571974 0.3351693218722893 1.0 0.7284786573839349 35 O60313,O00429,P62899,Q6P4A7,P00374 5 +Cough 0.3968501587414748 0.9634329256755524 0.335330309552869 1.0 0.7284870267512187 24 P04062 1 +Respiratory tract infection 0.2757775343642894 0.9624488410443504 0.3358241897504064 1.0 0.7285357714940964 163 Q9UJW0,Q09472,Q96EY7,P04062,P57076,Q9Y487,P50542,P07602,P13051,P09601,P14174,P06753,Q15650,Q9UHB7,P18074,Q9Y4I1,P53007,P20700,P54132,Q9P2R3,P26038,P63000,Q01968,Q8N1F7 24 +Abnormality of acid base homeostasis 0.2681040969208806 0.9580434992458544 0.3380408243075194 1.0 0.7308346339118093 172 Q05682,Q70HW3,Q969Y2,O43676,Q3LXA3,O75879,Q9H267,Q9HA77,Q9P0J0,P51970,Q08426,Q9HC21,Q10713,Q4J6C6,O75306,Q9UBX3,Q9H078,Q9Y6N5,P22695,Q4G176,O00429,Q86Y39,Q9BW92,Q6P4A7,O75380,P23786,Q9Y606,P14854,P12235,P53985,Q9NVI7,Q9Y3D3,Q01968 33 +Fatigue 0.3049449435229646 0.957898385478605 0.3381140006750267 1.0 0.7308346339118093 88 Q70HW3,Q13043,P07602,P06753,P25490,O60313,P12235,P04062,O00429,Q15165,P17252,Q4J6C6 12 +Infertility 0.4485875165828459 0.9552255356456798 0.3394636549758725 1.0 0.7319783741712301 16 P57076,Q8N8E3,P54132 3 +Abnormal circulating lipid concentration 0.3024084947650906 0.9543461329203892 0.3399084633660687 1.0 0.7322563365079435 80 Q9Y285,Q03252,P49257,Q15125,O75381,P40855,O75431,Q15800,Q15392,P28340,P50542,P37268,P07602,Q08426,P35573,Q9Y4I1,Q8N511,P23786,P51159,P02545,Q9NVI7,Q01968 22 +Polycystic liver disease 0.5752556456584962 0.9492563265641426 0.3424902600384614 1.0 0.7367911116187039 5 Q9H6U8 1 +Abnormal thoracic spine morphology 0.3643692329326043 0.9472370693211452 0.3435179900239011 1.0 0.7383168297407537 31 Q96AX1,P18074,P50542,P06753,Q9UHX1,Q96C36,P04062,P02545,O75844,P51648 10 +Arthrogryposis multiplex congenita 0.3429995029022181 0.9448969046941076 0.3447115119427133 1.0 0.739938300785082 40 P18074,Q9H267,P42356,P53007,P06753,Q6P3W7,Q15650,P04062,P02545,Q9UPT5,Q96S52,Q15392 12 +Bulbar signs 0.4768432780541791 0.9445065761030608 0.3449108429673344 1.0 0.739938300785082 13 P07602,P04062,Q9Y263,P06753 4 +Abnormality of fundus pigmentation 0.5738441759806695 0.9431335941985968 0.3456125743523222 1.0 0.7404158478268787 5 P38435 1 +Increased circulating igm level 0.5118656333283277 0.9393127842497172 0.3475701767552479 1.0 0.7435788368423302 10 P13051,Q13043 2 +Aplasia involving bones of the lower limbs 0.5308170710508171 0.9387168549804604 0.3478761373181238 1.0 0.7438901165160619 3 Q08AM6 1 +Memory impairment 0.3472000694491553 0.9366508047416052 0.3489382094389084 1.0 0.7443754083486642 38 O43681,P35240,P07602,P25490,Q9NR50,P08397,P00403,Q4G176,Q13144,Q96RR1,Q969G3,P31483,Q9NZJ7,P54886 14 +Shuffling gait 0.487616567337316 0.9363004588057204 0.3491185120112048 1.0 0.7443754083486642 12 P04062,P51608,P02545,P41227 4 +Increased circulating acth level 0.580985943236463 0.9357869050700398 0.3493829150043841 1.0 0.7443754083486642 4 P16435 1 +Parkinsonism 0.3629652345505818 0.9354550675810016 0.3495538290358269 1.0 0.7443874834221834 31 P04062 1 +Postaxial polydactyly 0.4084258321070391 0.9337118270135558 0.3504525625596431 1.0 0.7459587144290658 21 Q2VPK5,Q9Y263,Q15125,P17252,Q10713,Q9UM00 6 +Mitochondrial myopathy 0.3725853701393844 0.9282540144676747 0.3532758217516729 1.0 0.7494215872155193 28 O60313,Q9Y606,P12235,O43676,Q86Y39,P51530,O75306 7 +Non midline cleft lip 0.5316905924091178 0.927923534961628 0.3534472352760296 1.0 0.7494215872155193 8 O15111 1 +Generalized onset motor seizure 0.3168563306561175 0.9268137250475192 0.3540232575806836 1.0 0.7499048556510761 55 Q6PJG6,Q9HA77,P07602,P04062,Q4G176,Q96N66 6 +Carcinoid tumor 0.5788379342531123 0.92669331111755 0.3540857914193713 1.0 0.7499048556510761 4 P02545 1 +Poor eye contact 0.3457628542510504 0.9233986229434492 0.3557995090932642 1.0 0.7531351827411622 38 Q9P0J0,Q96N67,Q01082,P53007,O75380,Q9Y6M9,Q9UHX1,O43676,Q96RR1,Q96RP9,O96000,Q86Y39,Q16851,P51608,Q9GZZ9,O75306 16 +Feeding difficulties in infancy 0.2671574872584441 0.9227832800471032 0.3561201557824178 1.0 0.7531351827411622 171 Q09472,Q9Y285,Q9UQE7,Q15233,Q969Y2,Q9UHX1,Q6P3W7,O75381,Q9Y487,Q12959,Q9Y263,P50542,P37268,P07602,O60313,Q8IWS0,Q10713,O75306,O43681,P25490,P06753,P36507,P22695,Q15650,O00429,P18074,P53007,P27635,P63000,Q9Y3D3,Q01968 31 +Abnormal circulating ferritin concentration 0.5304040703165129 0.9218274694406368 0.3566185766434313 1.0 0.7531351827411622 8 P36551 1 +Decreased fertility in males 0.4603129484081122 0.9213999723478158 0.3568416432049062 1.0 0.7531351827411622 14 P57076,Q8N8E3,P54132 3 +Neoplasm of the skin 0.3217825905233834 0.9210846065331376 0.3570062563671803 1.0 0.7531351827411622 51 P18074,Q09472,Q01082,Q13043,P35240,P54132,Q06136,Q15126,P02545,P19447,Q969G3,Q9H1A4,P16615,Q01968,O60885 15 +Crumpled long bones 0.5267705556205826 0.9200672367891848 0.3575376242115613 1.0 0.7534292844749083 3 O75718 1 +Decreased circulating acth level 0.55921526925929 0.918468759132708 0.3583735073321628 1.0 0.7548476056301257 6 Q969G3,P35240 2 +Pancreatic fibrosis 0.4762615706181019 0.9174116324044256 0.3589269794693224 1.0 0.7555566752333448 2 Q9Y3E5 1 +Episodic tachypnea 0.5589290085962236 0.9172033358320286 0.359036099124042 1.0 0.7555566752333448 6 P22695 1 +Visual field defect 0.3289330029555526 0.916140156579072 0.3595933881974731 1.0 0.7557003389317702 47 O75695,P50542,P35240,O60313,O00429,O75381,Q9H061,O75306 8 +Mediastinal lymphadenopathy 0.5751419181356444 0.9110749406833902 0.3622558890626086 1.0 0.758887619382853 4 Q01844,O95999,O15460 3 +Sensory ataxia 0.5749209901096164 0.9101425465757412 0.3627473390044984 1.0 0.7592309993791669 4 P54802,Q96RR1 2 +Decreased absent ankle reflexes 0.4826673775405465 0.909755891352118 0.3629512611449734 1.0 0.7592689851664798 12 O60313,P12235,P49959,O95140,P54886 5 +Ventricular hypertrophy 0.3486014988993667 0.9089922569797272 0.3633542130225007 1.0 0.7594725570659663 36 Q9H267,Q15233,P35573,Q969Y2,P23786,P14854,P12235,P46976,P02545,O95630,O75431,Q9Y4J8 12 +Short middle phalanx of finger 0.5741975976178089 0.9070905367760672 0.3643589219534457 1.0 0.7599066116814046 4 Q9UHX1,Q8IWS0 2 +Slow decrease in visual acuity 0.5164110030731309 0.9063828255492058 0.3647332599330024 1.0 0.7599066116814046 9 O00429,Q969G3,O75306,P35240 4 +Increased circulating iga level 0.5739468180460185 0.9060328378999788 0.3649184717626652 1.0 0.7599066116814046 4 Q96BN8,P49327,O95394 3 +Abnormality of the temporomandibular joint 0.5236079786213143 0.9055289285567116 0.3651852414037866 1.0 0.7599066116814046 3 P02545 1 +Overtubulated long bones 0.5236079786213143 0.9055289285567116 0.3651852414037866 1.0 0.7599066116814046 3 P02545 1 +Thick hair 0.556283328935653 0.9055191917809964 0.3651903972526042 1.0 0.7599066116814046 6 Q9Y487,Q9UQE7,Q9UHB7 3 +Limited elbow movement 0.3480047007278746 0.903645180849964 0.3661835757967415 1.0 0.7604759951844088 36 Q9UQE7,O60568,Q7LGA3,P37268,P16435,P06753,P23786,P48651 8 +Peripheral axonal neuropathy 0.3123962483814266 0.901877221535265 0.3671220927883698 1.0 0.7618522928231345 58 O15269,P34897,P23381,P50570,O60231,Q7Z392,P07602,O60318,O60313,O95140,Q9HC21,P54886,Q96IJ6,Q8IV08,P08397,Q9H0B6,Q15650,Q96RR1,Q9NZJ7,Q96BR5,P12235,Q9NVI7 22 +Hyperkinetic movements 0.4811226725066172 0.9014892855235924 0.367328228080058 1.0 0.7619390001696417 12 P07602,Q7Z392,Q96TA2 3 +Abnormal brain positron emission tomography 0.555052670173739 0.9000912447051159 0.3680716949469929 1.0 0.7631397038346417 6 P35240 1 +Facial diplegia 0.503798719976692 0.8987645899438274 0.3687780649471697 1.0 0.7642624537751804 10 P42356,P34897,P06753,P12235,Q96TA2,O43819 6 +Hemoptysis 0.571933110909989 0.8975462985620978 0.3694274797692656 1.0 0.7649047937646077 4 P49815 1 +Increased total bilirubin 0.5718638848262276 0.8972547630778851 0.3695829892218985 1.0 0.7649047937646077 4 P23786,P14314 2 +Abnormal patella morphology 0.3600917246201577 0.8961194266209465 0.3701889826174707 1.0 0.7654755233784988 30 P25490,Q96PU5,Q15125,Q6ZXV5,Q9H1A4,Q01968 6 +Abnormality of circulating adrenocorticotropin level 0.5031707317293753 0.8956173448257327 0.3704571688423366 1.0 0.7655948497577432 10 O00170,P16435,Q969G3,P35240 4 +Hepatic cysts 0.5535758070544579 0.8935834540636355 0.3715448023757917 1.0 0.7667535090992826 6 Q9UBS4,Q9H6U8 2 +Aplasia hypoplasia of the tongue 0.562043375491819 0.8921517648247003 0.3723115921367188 1.0 0.7678098492641586 5 Q03252 1 +Chromosomal breakage induced by ionizing radiation 0.561414549065905 0.8894463747784744 0.3737632310300927 1.0 0.7697762501357217 5 P35240 1 +Multiple joint contractures 0.3918677382271253 0.8879516421037914 0.3745667640833243 1.0 0.7710885960436463 23 P18074,Q9H0B6,Q15650,Q9Y5P6,P02545,P51530,Q96S52,O75844 8 +Abnormal enchondral ossification 0.3589165306209715 0.886431905923454 0.3753848325540456 1.0 0.7720869936648428 30 P50542,Q15125,O75381,P38435,Q96HY6,Q9NUQ7 6 +Hypoplasia of the frontal lobes 0.5002102182181872 0.8807999163520609 0.3784261250420697 1.0 0.7755895294849846 10 Q00534,Q86XL3,Q08AM6,Q96C36,Q6UVJ0 5 +Poor head control 0.2996000688054799 0.8793364363754927 0.3792188854592289 1.0 0.7758630396865399 77 P53007,Q9P0J0,P51970,P07602,Q15233,P06753,O43676,Q15650,Q10713,P00374 10 +Abnormal facial expression 0.3431972471967477 0.8792994622716984 0.3792389273854315 1.0 0.7758630396865399 37 Q09472,Q86U42,Q9Y263,P06753,P51608,P12235,P50570,P04062,P51530,Q9Y5P4,Q9GZZ9,Q8WXI9 12 +Abnormal cardiac atrium morphology 0.2727006469365404 0.8789255883254086 0.379441623508852 1.0 0.7758630396865399 161 Q96AX1,Q09472,Q9UQE7,P34897,Q15233,Q86Y56,P42892,P40855,O95630,O75431,P57076,O75844,Q9Y4A5,Q9H267,Q13043,P16435,P21964,P61254,P62081,Q9H6U8,P55263,Q2VPK5,P25490,P36507,Q08AM6,P22695,Q15650,Q969G3,P62899,P53701,Q9UHB7,Q9NS87,P41227,Q9UM00,Q86XI2,P20700,P02545,P27635,P63000 39 +Atelectasis 0.4527416001492622 0.8782184771648045 0.3798251666533219 1.0 0.775871821205394 14 O00192,P21964,Q86Y56,P57076,Q01968 5 +Congenital contracture 0.3252063881805492 0.8780755413283848 0.3799027252235212 1.0 0.775871821205394 47 P18074,Q9H267,P42356,P53007,P25490,P06753,Q6P3W7,Q15650,P50570,P04062,P02545,Q9UPT5,Q96A33,Q96S52,Q15392 15 +High narrow palate 0.3383703492256117 0.8772553607381292 0.3803479524917774 1.0 0.7764390610972611 39 P18074,Q12873,P50542,Q01082,Q15233,Q13485,P16435,O60318,P06753,P23786,Q08AM6,P48651,P19447,O60826,P41227 15 +Cholestasis 0.2979014732215468 0.8690211101165584 0.3848355843966446 1.0 0.7830263623926309 78 P36551,Q00059,Q13043,P51159,O75381,Q8NB49,P53004,P55263,P00374 9 +Alacrima 0.5478220993230063 0.8682958727275829 0.3852323810292299 1.0 0.7830263623926309 6 Q03001 1 +Oculomotor apraxia 0.383649344328414 0.8672498984384106 0.38580510152676 1.0 0.7830263623926309 24 P04062,Q10713 2 +Dystrophic fingernails 0.4974048132934445 0.8667898406917152 0.3860571695377435 1.0 0.7830263623926309 10 P18074,P02545,P36507,O75844 4 +Split nail 0.5639803127010113 0.8641503411034713 0.3875053076700721 1.0 0.7841443065728739 4 P18074 1 +Reduced factor xii activity 0.5140382317801533 0.8617568891177643 0.3888213128708604 1.0 0.7851629895755119 3 Q10469,Q02750 2 +Abnormal bronchus physiology 0.5543440678858289 0.8591141219793397 0.3902775567991496 1.0 0.7855652803438911 5 P18074 1 +Bronchospasm 0.5543440678858289 0.8591141219793397 0.3902775567991496 1.0 0.7855652803438911 5 P18074 1 +Night sweats 0.4646163033741447 0.858903800621368 0.3903935924044401 1.0 0.7855652803438911 2 Q9UJS0 1 +Adrenal insufficiency 0.3638247592428619 0.8588734205201919 0.3904103550285429 1.0 0.7855652803438911 28 P51659,P50542,P35240,P16435,Q96IJ6,O95470,O75381,P40855,Q969G3,P33991,O75879,Q7Z392 12 +Recurrent bacterial infections 0.4053547820351811 0.8551503770924586 0.3924679035915068 1.0 0.7883367422228015 19 P13051,P57076,P51159,Q13043 4 +Encephalopathy 0.2984654103013687 0.854783229311952 0.3926711642052574 1.0 0.7884034288677234 104 Q9HA77,P53007,Q13043,P07602,O75380,P23786,Q9H078,Q9Y6N5,O43676,Q00839,P04062,Q4G176,O00429,Q9H6U8,Q86Y39,Q9NVI7,Q13813,O75306 18 +Patent ductus arteriosus 0.2982017657928619 0.8496958225370534 0.3954942215816781 1.0 0.7909884431633563 97 Q96AX1,Q09472,Q9UQE7,Q15233,Q9UHX1,Q6ZXV5,P42892,P40855,Q9Y4A5,Q15392,P21964,Q2VPK5,Q96PU5,P51571,Q15650,Q969G3,Q9UHB7,Q9UM00,Q86XI2,P02545,P63000,Q9Y3D3,Q9Y4J8 23 +Abnormality of the gingiva 0.3167159358983733 0.845753305743589 0.3976903791999757 1.0 0.7933272796777485 50 Q14108,P04062 2 +Irregular femoral epiphysis 0.5594081792688839 0.8450440980849863 0.3980862181876743 1.0 0.793775358072283 4 Q9NUQ7 1 +Abnormal social behavior 0.3018441866601102 0.8437319581588613 0.3988192049708421 1.0 0.794305009347106 70 Q09472,Q96N67,P49815,Q15233,Q9UHX1,Q8TB37,O43676,Q15125,Q2TAA5,Q9P0J0,P07602,Q96RP9,O96000,O75306,O43681,Q01082,P19447,Q96RR1,Q86Y39,Q9NZJ7,Q9GZZ9,P18074,P53007,O75380,Q9Y6M9,P09884,Q16851,P51608 28 +Breech presentation 0.5138004122367781 0.8436485140377887 0.3988658459361653 1.0 0.794305009347106 8 P06753,O60313 2 +Abnormal breath sound 0.4582569197602711 0.8420312013675363 0.3997704888615174 1.0 0.7957647000266187 13 P57076,Q969Y2,Q86Y56,P53007 4 +Prominent eyelashes 0.5029222534880377 0.8410586031643338 0.4003151047612925 1.0 0.7965067921344858 9 P20700,Q969G3 2 +Unusual infection 0.2568901616567186 0.8384516069135637 0.4017771158449508 1.0 0.7987301496814717 214 Q9UJW0,Q03252,P04062,P57076,Q9Y487,Q92993,Q12959,P50542,Q13043,P07602,P09601,Q9H6U8,Q9H1A4,P14174,P25490,P06753,Q9H078,Q15650,P41227,P18074,P53007,P51159,P27635,P26038,P63000,Q01968 26 +Abnormal chorioretinal morphology 0.3528590629756102 0.8366738682843242 0.4027759116325482 1.0 0.8001175387988997 30 Q09472,O75695,P50542,O75381,P53701,Q10713,Q01968,P41227 8 +Widely patent fontanelles and sutures 0.540572392871646 0.8365951442768412 0.4028201759181691 1.0 0.8001175387988997 6 P02545,O75844,O14802 3 +Corneal ulceration 0.5486680026851029 0.8348876139748699 0.4037809892265414 1.0 0.8010237056558293 5 P02545,Q96EK5 2 +Posterior pituitary dysgenesis 0.556148264656208 0.831466325490077 0.405710243992688 1.0 0.8037917483547444 4 Q9UHX1 1 +Abnormal circulating albumin concentration 0.3440320905437192 0.8297082517359387 0.4067037548757666 1.0 0.805071992999169 34 Q9P2R3,Q00059,Q13043 3 +Ascending tubular aorta aneurysm 0.5555475428244447 0.8289685201097745 0.4071222206121461 1.0 0.8052127196066167 4 P02545 1 +Distal peripheral sensory neuropathy 0.5553260471274606 0.828047879049127 0.4076433852265171 1.0 0.8052477908643627 4 P00403 1 +Abnormal circulating bilirubin concentration 0.35955777161066 0.8252900840909918 0.409206920059753 1.0 0.8072694814455383 28 Q9H267,P36551,P23786,P40855,P00390,P55263 6 +Pancytopenia 0.3369798551538062 0.8232321395088217 0.4103759953774892 1.0 0.8078569488620129 37 Q14108,P04062 2 +Hepatomegaly 0.2610515595247792 0.822027772085885 0.4110610909521597 1.0 0.8088621467123143 172 Q9UJW0,P14174,P36551,P53007,Q13043,P07602,P09601,O43676,Q3LXA3,P04062,Q14108,P00374 12 +Increased circulating gonadotropin level 0.5087308930784956 0.8199881482431524 0.4122228635676839 1.0 0.8104602186173802 8 P51659,P16435,P51809,Q15031,P09884 5 +Anorexia 0.3817821984320249 0.8166511922754642 0.4141277910812211 1.0 0.8128266043406185 23 P04062 1 +Prominent antihelix 0.4547626157061813 0.8099303323136724 0.4179802175253078 1.0 0.8184048203774401 2 Q10469 1 +Broad philtrum 0.4750806777554408 0.8098453981888124 0.4180290368105648 1.0 0.8184048203774401 11 Q969G3,Q01082,Q9UM00 3 +Ventricular arrhythmia 0.3259075264390375 0.8078940238704985 0.4191515918706692 1.0 0.8188734850031278 41 Q96AX1,P49815,Q969Y2,Q03001,P46976,P42892,Q8WXH0,Q99996,O75306,Q8NFF5,P36551,P08397,Q96RR1,P41227,P23786,O60333,P12235,P02545,Q9Y4J8 19 +Squamous cell carcinoma of the skin 0.5330806541058875 0.8040463594454214 0.4213702016576877 1.0 0.8212867606656601 6 P18074,P02545 2 +Onychomycosis 0.4535682293221884 0.8040317450603196 0.4213786416008407 1.0 0.8212867606656601 2 Q9Y5L0 1 +Abnormal macroscopic urine appearance 0.3844663654584147 0.8017911461647204 0.4226737810505376 1.0 0.8221626550447301 22 P53004,P36551 2 +Glaucoma 0.2940469769699675 0.8002595928033207 0.4235604091003275 1.0 0.8228214805059012 92 Q09472,Q01968,Q9UQE7,Q86XL3,P62854,Q3LXA3,Q15125,Q9Y5P6,O75381,P40855,Q92620,P50542,P21964,P50213,P61254,P62081,O60826,O75695,O00192,Q8WWY3,Q9Y3Z3,P62899,P53701,P41227,Q86XI2,O43395,Q9Y606,P12235,Q06136,Q13868,O43837,O60885 32 +Low levels of vitamin d 0.4941805996440754 0.7991275036285352 0.4242164832230712 1.0 0.8229341295727801 9 Q13043 1 +Abnormal choroid morphology 0.346580906624099 0.7990735765375674 0.4242477501464505 1.0 0.8229341295727801 31 Q09472,O75695,P50542,O75381,P53701,Q10713,Q01968,P41227 8 +Constriction of peripheral visual field 0.3788599130435005 0.7961297314661159 0.4259566347704697 1.0 0.8247260760822042 23 O75695,P50542,O60313,O75381,Q9H061 5 +Abnormality of the dorsal column of the spinal cord 0.4994026284348719 0.7955542954722991 0.4262911406279888 1.0 0.8247260760822042 3 P54886,Q6PI48 2 +Abnormality of central nervous system electrophysiology 0.2643480952302723 0.793154082479862 0.4276880563495173 1.0 0.8258066760667897 166 Q09472,Q96N67,Q15125,Q9Y5P6,O75381,P40855,Q14108,Q7Z392,Q2TAA5,Q9HA77,Q9Y263,P50542,P07602,P21964,P15311,O60313,Q00839,Q96F07,Q8IWS0,P42356,P00367,P36507,Q9UBX3,Q96S52,Q9GZZ9,P18074,P53007,P30622,P20700,P50897,Q96N66,P27635,Q96A33,Q9BSJ2,P51608,Q13813,Q01968,Q9NUQ7 38 +Shallow orbits 0.471615597099493 0.7922145516845301 0.4282355851243902 1.0 0.8265196388995308 11 O60568,P02545,Q9H6U8,O75431,O75844 5 +Abnormality of the supraorbital ridges 0.3674550817883162 0.789004348595243 0.4301094649187358 1.0 0.8282812084310806 25 P50542,P36507,O75381,P40855,Q8IWS0 5 +Impaired social interactions 0.311276060599379 0.7887626035821126 0.4302507703296734 1.0 0.8282812084310806 50 Q09472,Q96N67,Q9UHX1,Q8TB37,O43676,Q2TAA5,Q9P0J0,Q96RP9,O96000,O75306,Q01082,Q96RR1,Q86Y39,Q9GZZ9,P53007,O75380,Q9Y6M9,P09884,Q16851,P51608 20 +Short chin 0.4368873001627495 0.7887008249297645 0.4302868856681008 1.0 0.8282812084310806 14 P42345,Q08AM6,Q03001,P02545,Q96S52 5 +Proximal renal tubular acidosis 0.4978317710201033 0.7885091848974156 0.4303989281946663 1.0 0.8282812084310806 3 Q01968 1 +Abnormality of neuronal migration 0.2696282893317099 0.7871598106388367 0.4311883203869278 1.0 0.8293357926297173 158 Q03252,P34897,Q9H2M9,Q86XL3,Q96C36,Q6UVJ0,Q9Y5P6,O75381,Q6ZXV5,P42695,Q13409,P40855,P23258,O00139,Q9Y487,Q92993,Q9Y4A5,Q15392,Q2TAA5,Q9H267,Q9Y263,P50542,Q00534,P37268,P15311,P42345,Q9HC21,Q10713,Q2VPK5,P42356,Q96PU5,Q08AM6,Q969G3,Q9UPT5,Q96EK5,P30622,P20700,P23786,Q96N66,Q9BSJ2,P51608,P63000,Q9NUQ7 43 +Abnormality of alkaline phosphatase level 0.386365483699975 0.7842834734678819 0.4328737945642986 1.0 0.8316630383755029 21 Q8N511,Q92643,Q96A33,Q13043 4 +Flared metaphysis 0.4802072087055142 0.7816649859533408 0.4344114842427178 1.0 0.83237026249967 10 Q96HY6,Q9H6U8,Q08AM6,P48651 4 +Abnormality of vitamin d metabolism 0.4801820262231904 0.7815414097494419 0.4344841314442242 1.0 0.83237026249967 10 Q13043 1 +Temporal pattern 0.5142908914330375 0.7815166066425363 0.4344987133842108 1.0 0.83237026249967 7 P04062 1 +Median cleft palate 0.448790683786204 0.7805256784330117 0.4350815189988051 1.0 0.832758047620475 2 Q14739 1 +Right ventricular dilatation 0.4956687944689054 0.778829415994797 0.4360802071864285 1.0 0.8333324402170621 3 Q9H6U8 1 +Patchy hypopigmentation of hair 0.5426167823959729 0.7755480376624952 0.4380158914112502 1.0 0.8355153811183518 4 Q9UM00 1 +Jaundice 0.3011816348370727 0.7750617863281607 0.4383031507506107 1.0 0.8355153811183518 58 P36551,P50542,Q00059,Q13043,P51159,O75381,P40855,Q8NB49,P00374 9 +Abnormality of upper lip vermillion 0.277299592539063 0.773468150277474 0.4392453709392323 1.0 0.8362798930900539 142 Q09472,Q9UQE7,P34897,Q15233,Q86XL3,Q9UHX1,Q96C36,Q6UVJ0,P04062,Q9Y4A5,Q6PJG6,Q9Y263,Q00534,P42345,P62081,Q00839,Q92643,Q96F07,Q9H6U8,Q4J6C6,Q2TAL8,P25490,P35573,P51571,Q92974,Q969G3,Q9UHB7,Q9NS87,P41227,Q7LGA3,Q86XI2,O15344,P27635,Q9BSJ2,P51608,Q01968,Q8WXI9 37 +Reduced circulating prolactin concentration 0.5339878462474658 0.772813725499343 0.4396326292088215 1.0 0.8364324927771408 5 P35240 1 +Serositis 0.4012871497268315 0.7727229451295673 0.439686364300667 1.0 0.8364324927771408 18 P14174 1 +Abnormality of metacarpophalangeal joint 0.541528543750885 0.7710843754023291 0.4406569211658016 1.0 0.8372481502150231 4 Q15233 1 +Nyctalopia 0.3445524193853563 0.7690030140050728 0.4418915212825356 1.0 0.8382197596832385 30 O75695,P50542,Q6P4Q7,P50213,Q8WWY3,O75381,P40855,O95140,P38435,Q92620,Q10713,O43837 12 +Gray matter heterotopia 0.340916069823834 0.7673037408940084 0.4429009447769598 1.0 0.8384761165168132 32 Q00534,Q86XL3,Q96PU5,Q96C36,Q9Y5P6,Q6UVJ0,Q6ZXV5,P42695,P23258,Q9BSJ2,O00139,Q2TAA5 12 +Back pain 0.3793747717178774 0.7669489993983744 0.4431118389702744 1.0 0.8384761165168132 22 P36551,Q01082,P35240,Q13485,P08397,P02545,Q8WXH0,Q969G3 8 +Abnormal t wave 0.5323450396721887 0.7659251565041041 0.443720836433588 1.0 0.8388791435426994 5 Q99996,P46976 2 +Knee flexion contracture 0.3689292058376715 0.7613815245970301 0.4464292193535888 1.0 0.8416615945194135 24 Q7LGA3,P37268,P06753,Q86XL3,P23786,P48651,Q9Y5P6,P27635 8 +Cerebellar dysplasia 0.5387568812706371 0.7597399686953948 0.447410032596194 1.0 0.8423346048617716 4 P63000 1 +Tics 0.5093524396925664 0.7595678033334693 0.4475129706157341 1.0 0.8423346048617716 7 Q9UHX1,Q8WXI9 2 +Cerebral white matter atrophy 0.3733399662230289 0.7575636805443141 0.4487122298210417 1.0 0.8426533920327166 23 Q9Y263,P51970,O60313,P51572,O00429,Q7Z392,Q2TAA5 7 +Abnormal scrotal rugation 0.4440131382502268 0.757168808445317 0.4489487346776102 1.0 0.8426533920327166 2 Q96GM8 1 +Nodular goiter 0.4440131382502219 0.7571688084452929 0.4489487346776246 1.0 0.8426533920327166 2 Q9UPY3 1 +Vertebral arch anomaly 0.5368403093440784 0.7519162729065754 0.4521014114128467 1.0 0.8477078050561192 4 Q96HY6 1 +Thoracic kyphosis 0.3889729058288776 0.749459719916782 0.4535801677877082 1.0 0.8485866254494817 19 P04062,Q9UHX1,P51648 3 +Immunologic hypersensitivity 0.3343725404803631 0.7468286173987474 0.4551670189293135 1.0 0.8505134129203941 34 P18074,Q09472,P50542,Q01082,Q13043,P21964,P42345,Q9H6U8,Q9UHB7 9 +Polymicrogyria 0.2883588195278275 0.7458379345344366 0.4557653213923514 1.0 0.8505134129203941 78 P34897,Q9H2M9,Q6ZXV5,O75381,P40855,Q9Y487,Q92993,Q9Y4A5,Q15392,P50542,P37268,P15311,P42345,Q10713,P42356,Q96EK5,P30622,P23786,Q96N66,P51608,P63000,Q9NUQ7 22 +Decreased muscle mass 0.413449788047567 0.7456750426026962 0.4558637389542008 1.0 0.8505134129203941 16 P51659,Q9Y285,O95202,P46976,Q9Y487,Q06210 6 +Abnormality of the hypothenar eminence 0.5352959025629707 0.7456245160183719 0.4558942690049998 1.0 0.8505134129203941 4 Q96IJ6,Q7Z392 2 +Kyphosis 0.26967850164578 0.7452450737924862 0.456123578930669 1.0 0.85059891871383 154 Q15233,Q32P28,Q9UHX1,Q15125,P04062,P04350,Q14108,Q9Y487,Q9Y263,Q9H6U8,P51530,Q8IWS0,P06753,Q9H0B6,P51648,P41227,P18074,P53007,Q9Y606,Q9NUQ7 20 +Fibrous tissue neoplasm 0.3759186304593155 0.7434274068225712 0.4572229564858887 1.0 0.850861240863139 22 Q13126,Q15392 2 +Abnormality of macular pigmentation 0.4876776656406555 0.7432893957860285 0.4573064902948387 1.0 0.850861240863139 3 Q9UM00 1 +Abnormally folded helix 0.3801961683838518 0.7431176407921655 0.4574104602452498 1.0 0.850861240863139 21 O00192,O15111,P21964,P23786,Q96C36,P41227 6 +Narrow palm 0.4874551971326012 0.7423052177165723 0.4579024312272017 1.0 0.850861240863139 3 Q9BPU6,P52788 2 +Loss of eyelashes 0.4869700137967305 0.7401598380281729 0.4592030137757752 1.0 0.851205586511193 3 P02545 1 +Thin clavicles 0.4869700137967305 0.7401598380281729 0.4592030137757752 1.0 0.851205586511193 3 P02545 1 +Episodic vomiting 0.4610114586144394 0.7386838320876291 0.4600990056204803 1.0 0.8519129243647944 11 P36551 1 +Retinal coloboma 0.4812431481952598 0.7377752961325291 0.4606510076099765 1.0 0.8525261761596213 9 Q9UHX1 1 +Abnormality of adrenal physiology 0.3306509663524987 0.7346094697110526 0.4625773690857508 1.0 0.8554083299088715 35 P51659,P50542,P35240,P16435,Q96IJ6,O95470,O75381,P40855,Q969G3,P33991,O75879,P17252,Q7Z392,Q01968 14 +Eeg with spike wave complexes 0.4380114464500304 0.7324162096201023 0.4639145680148551 1.0 0.8562766028814937 13 Q14108 1 +Abnormal prolactin level 0.5161985263577615 0.7316115462258251 0.464405698831988 1.0 0.8563980985620909 6 P35240 1 +Rod cone dystrophy 0.3200753029028714 0.7300462931294405 0.4653618881814259 1.0 0.8573715738008129 40 O75695,P50542,O75381,P27635,P38435,P57076 6 +Leukodystrophy 0.2967128349533925 0.7288527943901059 0.4660917131166648 1.0 0.8573715738008129 59 O43678,Q9P0J0,O43681,O75380,P07602,P20700,Q969Y2,P14854,O43676,Q86Y39,P04350,O75306 12 +Fragile nails 0.4687092242707441 0.7256215300769344 0.4680708186389273 1.0 0.8590563401465032 10 P18074,P02545,Q9Y487,Q13555 4 +Decreased proportion of cd3 positive t cells 0.4374440131382489 0.7253168692943562 0.4682576590498715 1.0 0.8590591639711929 2 O95394 1 +Premature skin wrinkling 0.3932917514955133 0.7231511736907211 0.4695870125053289 1.0 0.8602102509414744 18 P36507,O14802,P02545,O75844,Q9Y487,P41227 6 +Increased urine alpha ketoglutarate concentration 0.5216511104112204 0.7214039831596315 0.4706609966396289 1.0 0.8602102509414744 5 P00367 1 +Proximal muscle weakness in lower limbs 0.4008761955590606 0.7191679785918166 0.4720374266498681 1.0 0.8602254651936109 17 P36551,P08397,P12235,P50570,P02545,O95140,Q8WXH0 7 +Tachycardia 0.3458646158968137 0.718720627310881 0.4723130712450567 1.0 0.8602254651936109 28 Q96AX1,Q8NFF5,P36551,P23786,Q03001,P46976,P42892,P02545,Q99996,P41227 10 +Ambiguous genitalia 0.3719130073724448 0.7163095763505386 0.4738002149516047 1.0 0.8612172723124882 22 Q15392 1 +Esodeviation 0.3185724589257041 0.7162183678633665 0.473856523117218 1.0 0.8612172723124882 40 P18074,P53007,P50542,P20700,Q9UHX1,Q96C36,P04062,Q9H6U8,Q9NVI7 9 +Tracheal stenosis 0.4861682347534833 0.7161895270261893 0.4738743289651794 1.0 0.8612172723124882 8 Q15125,Q96HY6 2 +Pituitary growth hormone cell adenoma 0.5199626101462835 0.7144282053512075 0.4749624361685942 1.0 0.8619676238674495 5 Q9H6U8 1 +Narrow mouth 0.2866891628995606 0.7142114673810191 0.4750964269959907 1.0 0.8619676238674495 77 Q09472,Q15233,P83436,Q6P3W7,P04062,O75431,O75844,Q9Y487,Q15392,P28340,P16435,P21964,Q13485,O14802,O00192,Q15650,Q96PZ0,Q7LGA3,P33992,P02545,P27635,Q9NVI7,P51608 23 +Abnormal lung lobation 0.4234763264752459 0.7142013024042211 0.4751027116540316 1.0 0.8619676238674495 14 O15111,Q9UHX1 2 +Limited extraocular movements 0.4988871581563479 0.7134774588981541 0.4755503566610002 1.0 0.8619676238674495 7 P51659,O75306,O43819,Q9BVA1 4 +Splenomegaly 0.2862744579926981 0.7110864792395223 0.4770306479854382 1.0 0.8635278339426016 87 P14174,Q13043,P07602,P04062,Q14108,Q15392 6 +Fetal onset 0.4752959195654045 0.7098964208259728 0.4777683701181539 1.0 0.8635278339426016 9 Q9Y285,P27635 2 +Anemia of inadequate production 0.2915453658812469 0.7079004022378533 0.4790071099229207 1.0 0.8644129862213549 68 Q9Y285,O60313,Q9Y606,Q9UBX3,Q3LXA3,O00429,P62899,Q6P4A7,P00374 9 +Osteomyelitis 0.4438801277395544 0.7057430300334439 0.4803479562341564 1.0 0.865001294025584 12 O15269,Q13126 2 +Congenital malformation of the great arteries 0.2849795004869787 0.7053622768170824 0.4805848135246893 1.0 0.865001294025584 119 Q09472,Q9UQE7,Q15233,Q9UHX1,Q6ZXV5,Q86Y56,P42892,P40855,P57076,Q9Y4A5,Q15392,O15111,P21964,Q2VPK5,Q2TAL8,Q96PU5,P51571,Q08AM6,Q15650,Q969G3,Q9UHB7,Q9UM00,Q86XI2,P02545,P63000,Q9Y3D3,Q9Y4J8 27 +Erythema nodosum 0.4332636607942702 0.7052186303605983 0.4806741890119061 1.0 0.865001294025584 2 P98170 1 +Narrow nose 0.5099196370318984 0.7050404974126223 0.4807850342487771 1.0 0.865001294025584 6 O75431,P49589,Q9Y4A5 3 +Abnormality of bladder morphology 0.4740842518868286 0.7042440051252087 0.4812808308324867 1.0 0.8651484807054706 9 Q9H6U8 1 +Abnormal circulating pyruvate family amino acid concentration 0.3901021546183998 0.7035299165162122 0.4817255696872617 1.0 0.8656123027403665 18 P22695,Q9P0J0 2 +Abnormal pelvis bone morphology 0.4766826683801267 0.695017363565517 0.4870444200587138 1.0 0.8704313210832708 3 P16435 1 +Cachexia 0.3966380271399986 0.6938850675606764 0.4877542888040735 1.0 0.8704313210832708 17 P04062 1 +Joint laxity 0.2850358198018062 0.6933638640315568 0.4880812337540656 1.0 0.8704313210832708 77 Q09472,Q15233,Q32P28,Q9H2M9,Q9NR45,Q9UHX1,Q9Y5P6,P49959,Q9Y487,Q9Y2D4,Q9Y4R8,Q96HY6,Q06210,P61978,Q01082,P25490,Q15650,Q969G3,Q96S52,P53007,P51532,Q96A33,Q15436,P63000,Q8WXI9 25 +Slowly progressive 0.2934930454170413 0.6929351126861628 0.4883502731099196 1.0 0.8704313210832708 59 O14773,P23381,Q9NXN4,P50570,P46976,Q9P0J0,O60318,O95140,P51530,P54886,P41250,Q8IV08,O00429,Q96BR5,O43707,P12235,Q5JTV8,P02545,P31483,P51608,O14979 21 +Cystic liver disease 0.4805367532966836 0.6907322809368021 0.4897337990939003 1.0 0.8710983341482135 8 Q9UBS4,Q9H6U8 2 +Supernumerary tooth 0.4710851779158602 0.6902953539072906 0.4900084690391608 1.0 0.8710983341482135 9 Q09472,Q9UHX1 2 +Diastema 0.4708435101784387 0.6891740180920627 0.4907137650562747 1.0 0.8710983341482135 9 P17252,Q9BSJ2,Q8WXI9 3 +Abnormally lax or hyperextensible skin 0.310174555108875 0.688155177948826 0.4913550662997421 1.0 0.871538785468693 44 P25490,Q9UHX1,P04062,P38435,Q9Y487,Q9Y3D3,P41227 7 +Decreased lacrimation 0.4792015862811578 0.6847267054004936 0.4935163938639761 1.0 0.8732603060890815 8 Q03001 1 +Abnormal elasticity of skin 0.2904797985974773 0.683578186187432 0.4942415631201471 1.0 0.874209800314766 65 P25490,P36507,Q9UHX1,Q15650,P04062,Q13126,P38435,Q9Y487,Q9Y3D3,P41227 10 +Ecchymosis 0.4391957436833033 0.681746377028968 0.4953993366234475 1.0 0.8752558401624628 12 P04062 1 +Progressive flexion contractures 0.4281875186622865 0.6810060854925125 0.4958676398132675 1.0 0.8757494773997364 2 Q12904 1 +Enamel hypoplasia 0.4020741883936499 0.6796074700849646 0.4967530384488126 1.0 0.8763116766547546 16 P18074,P51648,Q01968 3 +Supraventricular arrhythmia 0.3856453663997425 0.6762763191367613 0.4988652249462002 1.0 0.8793685105895758 18 Q8NFF5,P12235,P02545,Q8WXH0,Q99996,O95235,Q9Y4J8,P41227 8 +Type 1 muscle fiber atrophy 0.4902164494988109 0.6757741312703539 0.4991840612684302 1.0 0.8795960881947709 7 P06753,P02545,Q8WXH0 3 +Generalized joint laxity 0.4478764435538414 0.6734030772508447 0.5006908914358101 1.0 0.880750046755368 11 Q9UHX1 1 +Widow s peak 0.5165020735380195 0.6700551909371545 0.5028226080383669 1.0 0.8822006218231335 4 O15344 1 +Generalized amyotrophy 0.3394875307844965 0.6698621104146335 0.5029456953146121 1.0 0.8822006218231335 28 Q03252,P49589,Q13043,P06753,Q9Y606,O14802,Q15650,Q9Y5P6,P02545,P51530,O43819 11 +Abnormality of prenatal development or birth 0.2477407390943816 0.6684406525123217 0.5038523531506245 1.0 0.8826381584828092 258 Q09472,Q9Y285,Q9UQE7,Q70HW3,Q9UHX1,Q6P3W7,O43676,Q96EY7,Q15125,P04062,Q86Y56,O75381,P50570,P40855,O75879,Q99996,P57076,Q9Y487,Q9HA77,P50542,P16435,O15111,P21964,O60313,P61254,P62081,Q96F07,Q9H6U8,P51530,Q9HC21,Q9Y5P4,Q4J6C6,O75306,Q2TAL8,P06753,P36507,O75718,Q08AM6,Q15650,O00429,Q86Y39,Q96S52,P62899,Q9GZZ9,Q9UM00,P18074,P53007,O75380,P23786,P27635,Q9NVI7 51 +Sleep apnea 0.3354668794678487 0.6660055384326455 0.5054075603533821 1.0 0.8832880947064465 29 Q09472,P53007,Q15233,P51530,Q9UHB7 5 +Abnormal shoulder physiology 0.4699611124867553 0.6659063709533682 0.5054709480707944 1.0 0.8832880947064465 3 P02545 1 +Respiratory failure 0.2884147722913738 0.6629791952108588 0.5073438787078879 1.0 0.8850639919752075 66 Q70HW3,P07602,P06753,Q969Y2,P23786,P54132,Q9H078,Q96EY7,Q15165,P57076,P53701,O75306 12 +Abnormality of hepatobiliary system physiology 0.2801008225985365 0.6622261058180144 0.5078263258835127 1.0 0.8850639919752075 80 P50542,Q00059,Q13043,Q8N511,P23786,P22695,P04062,O75381,P40855,Q96A33,P53004,P55263,Q10713,O75306 14 +Entropion 0.4649558665416471 0.6619829689657974 0.5079821365976209 1.0 0.8850639919752075 9 P18074,P02545,P19447,O75844 4 +Bird like facies 0.486749359121739 0.6608328185448049 0.5087195336061829 1.0 0.8855669550824836 7 P18074,P02545,O75844 3 +Renal agenesis 0.2938008398554377 0.6605258675977236 0.50891642415829 1.0 0.8855669550824836 54 Q2VPK5,Q7LGA3,O75306,Q00534,P16435,Q86XL3,Q9UHX1,Q96C36,P61254,P62081,Q6UVJ0,P62899,Q15392 13 +Rhizomelia 0.4060628134854527 0.6592001365216411 0.5097672592747071 1.0 0.8864519932473902 15 O75718,P42345,Q15125,Q9UBN7,Q9H6U8,Q15392 6 +Pterygium 0.4231305340056203 0.6536880043115414 0.5133128331766184 1.0 0.8889496804657463 13 O15111 1 +Petechiae 0.4531783494582321 0.6513054689622704 0.5148493187439895 1.0 0.891021888024033 10 P04062 1 +Generalized muscle weakness 0.3248116483684854 0.6496985782750425 0.5158869424549426 1.0 0.8917499916905852 33 P06753,P53007,Q15165,P12235 4 +Delayed ability to walk 0.2828567566100175 0.6483901733344071 0.5167326244333945 1.0 0.8920738668939717 75 Q09472,Q6PJG6,Q03252,Q12873,P53007,P34897,Q15233,P25490,Q86XI2,P20700,Q6ZXV5,Q96N66,Q13409,Q16512,P27635,Q10713,Q9Y4A5 17 +Excessive wrinkled skin 0.4618250678510844 0.6476278674735488 0.5172256685496774 1.0 0.8923923332327148 9 Q9Y487 1 +Postural tremor 0.3805082127844141 0.6451172495059463 0.5188512062886603 1.0 0.8935342467883467 18 Q9HA77,O14773,P20700,O14802,O95140,P04350,Q14108,O75569,O75306 9 +Corneal dystrophy 0.4952964434785594 0.6440660195184766 0.5195326240746518 1.0 0.8936913685782641 6 Q3LXA3 1 +Right bundle branch block 0.4513965096223861 0.6428955960310537 0.520291847237432 1.0 0.8936913685782641 10 Q99996 1 +Abnormality of the diaphragm 0.3286959046893183 0.6422223970944553 0.5207287927433617 1.0 0.894021062927664 30 O60568,O15111,Q15650,Q9H6U8,P53701 5 +Abnormality of carpal bone ossification 0.4822834984257667 0.6417087309211854 0.521062319247314 1.0 0.894021062927664 7 Q9NUQ7 1 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2470800171365048 0.6412557812120739 0.5213565134203404 1.0 0.894074722807809 253 Q09472,Q9UQE7,Q9H2M9,Q86XL3,Q9UHX1,P83436,Q6P3W7,Q15125,P04062,O75381,P40855,O75431,Q9Y4A5,Q15392,Q96HY6,Q6PJG6,P28340,Q9H267,Q9Y263,P50542,P37268,P16435,O15111,P21964,P61254,P62081,Q00839,Q9H6U8,P51530,Q9HC21,Q2VPK5,P42356,P25490,P06753,Q96PU5,P51571,Q08AM6,P48651,Q15650,P62899,P53701,Q9UHB7,P41227,P18074,Q9UM00,Q7LGA3,Q86XI2,P53007,P33992,Q9Y606,P54132,P02545,P27635,Q9NVI7,P51608,Q01968,Q8WXI9 57 +Nonimmune hydrops fetalis 0.3318998025084133 0.6384176777971213 0.5232018264859883 1.0 0.8957613667396085 29 P04062,Q9HA77,P62899 3 +Abnormality of circulating glucocorticoid level 0.4095492965458798 0.6383652716100223 0.5232359320817213 1.0 0.8957613667396085 14 O75879,P17252,P16435,P35240 4 +Avascular necrosis 0.3640542135031916 0.6371999538676234 0.5239946077353974 1.0 0.8960675033055339 21 Q14108,P04062,Q8IWS0,Q9NUQ7 4 +Abnormality of female external genitalia 0.3158424867623576 0.6365836024953738 0.5243961088380829 1.0 0.8960930190097134 37 Q9UQE7,P50542,P16435,Q08AM6,P02545,O75381,P40855,P53701,Q15392 9 +Primary microcephaly 0.394267982339713 0.6349667791418845 0.5254500818739252 1.0 0.8961179823915508 16 Q08AM6,Q9UQE7,Q03252,Q9H078 4 +Narrow palate 0.292472062932025 0.6344858689586712 0.5257637860450859 1.0 0.8961179823915508 53 P18074,Q09472,Q12873,P50542,Q01082,Q15233,P16435,Q13485,O60318,P06753,P23786,Q08AM6,P48651,Q5T160,P19447,O60826,Q01968,P41227 18 +Aplasia hypoplasia of the phalanges of the hand 0.2878186075580266 0.6338338676837363 0.5261892481078374 1.0 0.8962067900757927 60 P38435,Q9UQE7,P16435,Q9H2M9,O15111,Q9UHX1,P42345,Q08AM6,P48651,P02545,Q969G3,O95630,Q9H1A4,Q96S52,P51608,Q8IWS0,Q9NS87 17 +Abnormality of the pylorus 0.3116241339556544 0.6335123414666772 0.5263991241181916 1.0 0.8962123905295394 39 Q9UQE7,P50542,Q96PU5,P50570,Q6ZXV5,O75381,P41227 7 +Vasculitis 0.4793114348901302 0.6290605869608641 0.5293093920221903 1.0 0.8987941440057667 7 Q96BN8,Q9Y3Z3,O15460,O95394,P49327 5 +Selective tooth agenesis 0.4912800247479111 0.6275639068494849 0.5302896591620314 1.0 0.8987941440057667 6 Q12959,P41227 2 +Abdominal wall muscle weakness 0.4981590755765028 0.6258623185100946 0.5314052520965933 1.0 0.8987941440057667 5 P36507 1 +Broad based gait 0.3265330005466303 0.6252309663020639 0.5318194807886272 1.0 0.8991667078541487 30 Q05682,Q12873,P50542,P49589,Q01082,P51608,Q3LXA3,P04062,Q9Y5P4 9 +Exodeviation 0.3494481296097955 0.6246375766564339 0.5322089514252308 1.0 0.8992143359905417 24 Q15233,Q9UHX1,Q9UEY8,Q8IYI6,P27635,Q7Z392,Q9UHB7 7 +Pruritus 0.3618184009117185 0.6227701154944019 0.5334355993145883 1.0 0.9002575312786426 21 Q15126,Q13043 2 +Adult onset 0.2812944834908584 0.6215855763129239 0.5342144077284818 1.0 0.9009159673442132 74 P36551,P31483,P07602,P12235,Q15126,P04062,P38435,Q14566,O14979,P17096 10 +Abnormal circulating dicarboxylic acid concentration 0.3049942057252505 0.6207995311628933 0.5347315317696917 1.0 0.9009673584004684 42 Q9H267,P36551,P37268,P22695,Q4G176,P40855,P00390,P55263 8 +Hyperextensibility of the finger joints 0.5038502634142201 0.6203578028880053 0.5350222471260762 1.0 0.9009673584004684 4 Q9Y263 1 +Bulbar palsy 0.4164833546835928 0.6191483771089971 0.535818616110479 1.0 0.9012502881278674 13 P53007,P31483,Q9Y263,P06753 4 +Prominent nose 0.3388204138796962 0.6190518730806247 0.5358821866988848 1.0 0.9012502881278674 26 Q09472,Q12873,Q15233,P54132,P40855,Q13409 6 +Restrictive behavior 0.4964295248223902 0.6189690220932966 0.5359367665802086 1.0 0.9012502881278674 5 P51608,Q01082 2 +Testicular dysgenesis 0.4141534786503446 0.6152832461008245 0.53836767992569 1.0 0.903646837123642 2 Q8IY37 1 +Abnormality of facial soft tissue 0.2768502316856958 0.6126124850426634 0.5401326009494882 1.0 0.904644052746325 124 Q03252,P34897,P35240,Q9UHX1,Q13555,Q9Y5P6,P04062,O75381,P50570,P40855,Q9Y263,P50542,P16435,O60313,Q96TA2,P51530,Q9H1A4,P42356,P25490,P06753,P48651,O00429,Q969G3,Q86U42,P53007,P12235,P02545,Q9P2R3,P51608,Q8N1F7 30 +Abnormal urinary color 0.4627616606814504 0.6118249875024777 0.5406535555963528 1.0 0.9047733710160444 8 P53004 1 +Abnormal talus morphology 0.3634894102566361 0.6103230181041308 0.5416478519733299 1.0 0.9047733710160444 20 P18074,Q9Y263,P16435,Q9UHX1,Q08AM6,Q6P3W7,P02545,Q9UPT5 8 +Hyperpituitarism 0.3746813432515972 0.6101369184021179 0.5417711125842406 1.0 0.9047733710160444 18 P51659,P35240,P16435,O00170,O14802,P09884,Q969G3,P33991 8 +Hypokalemia 0.4345130828571492 0.608385501814899 0.5429318249149087 1.0 0.9063852863901752 11 Q99996,Q01968 2 +Multicystic kidney dysplasia 0.3659831781879201 0.6052017523773782 0.5450449516133018 1.0 0.9092581488590382 19 O75381,Q9UQE7,P50542,Q10713 4 +Positive romberg sign 0.4733141535025155 0.6037407607411374 0.5460160099329956 1.0 0.909974714674278 7 Q8IV08,P18887,O14802,Q96RR1,O95140 5 +Intestinal malrotation 0.3191517676297864 0.6035159878584124 0.5461654828951295 1.0 0.909974714674278 33 Q09472,Q9UQE7,Q00839,Q86Y56,P57076,Q15392 6 +Adrenal hyperplasia 0.4848121926400651 0.6012336231587518 0.5476843927250548 1.0 0.9105812991873654 6 P17252 1 +Retinal hemorrhage 0.4913906244278203 0.5990085711455759 0.5491671689255608 1.0 0.911242236273386 5 Q9Y487 1 +Fragile skin 0.4510861988209997 0.5989853420933391 0.5491826592208455 1.0 0.911242236273386 9 P36551 1 +Dermatological manifestations of systemic disorders 0.2799084433225045 0.5979430215238253 0.5498779525084703 1.0 0.9113055325847436 73 P36551,P50542,Q00059,Q13043,P53007,Q969Y2,P51159,O75381,P40855,Q8NB49,P00374 11 +Submucous cleft of soft and hard palate 0.3499087009218021 0.59753303478936 0.5501515582229848 1.0 0.9113055325847436 23 Q7LGA3,P49589,P36507,P48651,P02545,P62266,O75844,Q92993,Q15392 9 +Preaxial polydactyly 0.394776036877409 0.5970344775714257 0.5504843620009758 1.0 0.9113055325847436 15 Q2VPK5 1 +Short lingual frenulum 0.4966863204123807 0.5926982657328139 0.5533831022907794 1.0 0.9129836520356062 4 P02545 1 +Hand clenching 0.470533496687723 0.5920972726562747 0.5537854531506381 1.0 0.913117541825638 7 Q03001 1 +Asthma 0.3400151183282116 0.5919886614435547 0.5538581811073542 1.0 0.913117541825638 25 P18074,Q09472,P50542,P21964,Q9H6U8,Q9UHB7 6 +Abnormal morphology of the great vessels 0.2424228711004255 0.5910682375804203 0.5544747006095638 1.0 0.9132442450755162 193 Q09472,Q9UQE7,Q15233,Q9UHX1,Q6ZXV5,P04062,Q86Y56,P42892,P40855,P57076,Q9Y4A5,Q15392,O15111,P21964,P61254,P62081,Q9H6U8,P55263,Q2VPK5,Q2TAL8,P06753,Q96PU5,O75718,P51571,Q08AM6,Q15650,Q969G3,P62899,Q9UBS4,P53701,Q9UHB7,P41227,Q9UM00,Q7LGA3,Q86XI2,P02545,P27635,P63000,Q9Y3D3,Q9Y4J8 40 +Tongue thrusting 0.4961068219985056 0.590477149133864 0.5548708011671204 1.0 0.9132442450755162 4 Q9NS87 1 +Narrow nasal bridge 0.4701031393110499 0.5903008600369375 0.5549889628997777 1.0 0.9132442450755162 7 Q15233 1 +Bradykinesia 0.3397242504822993 0.5899566866771659 0.5552196882730152 1.0 0.9132442450755162 25 P06753,P04062,P12235 3 +Spastic paraparesis 0.3712204254659897 0.5895578209263057 0.5554871366942926 1.0 0.9132442450755162 18 P04062 1 +Frequent falls 0.3045452463782792 0.5893290529368368 0.5556405591410973 1.0 0.9132442450755162 40 P53007,O43681,P07602,P06753,P12235,P04062 6 +Hepatic failure 0.294750148518905 0.5887833765103397 0.5560065986230647 1.0 0.9132442450755162 48 P04062,O75381,Q00059,Q13043 4 +Abnormal anatomic location of the heart 0.4395672567192126 0.587754218811567 0.5566972771645489 1.0 0.9135747174990614 10 P57076,Q86Y56,Q10713,P02545 4 +Respiratory distress 0.2839833920450223 0.5838788630409777 0.5593018148745483 1.0 0.9171995803885412 57 P53007,P51970,P07602,Q9UHX1,P04062,P04350,P53701,O75306 8 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3586894435434703 0.5803394047230434 0.5616857593972946 1.0 0.91861608081767 20 P22695,Q9P0J0 2 +Cardiovascular calcification 0.4467766474284313 0.5797447005209393 0.5620867942703625 1.0 0.91861608081767 9 O75431,P04062,P02545 3 +Neoplasm of the gallbladder 0.4862968621707251 0.5790241031132667 0.5625729096932219 1.0 0.91861608081767 5 P07602,Q13043 2 +Biliary tract neoplasm 0.4862968621707251 0.5790241031132667 0.5625729096932219 1.0 0.91861608081767 5 P07602,Q13043 2 +Bowing of the legs 0.2890461433804919 0.5786749864711717 0.5628084969426239 1.0 0.91861608081767 51 Q01968,P36507,Q32P28,Q08426,Q13126,Q9H1A4,P17252,Q96HY6,Q9NUQ7 9 +Visual loss 0.2905539751727007 0.5772331126611676 0.5637819912250461 1.0 0.91861608081767 50 Q9HA77,P35240,P07602,O60313,P14854,P50897,O00429,Q10713,O75306 9 +Decreased calvarial ossification 0.4925454276868704 0.5768825159697332 0.5640188223463936 1.0 0.91861608081767 4 O75718,P02545 2 +Muscular hypotonia of the trunk 0.2756071013975273 0.5767303281996659 0.5641216414234493 1.0 0.91861608081767 86 Q6PJG6,P07602,Q96PU5,Q15233,O60313,Q2TAA5,P20700,Q9HC21,Q6ZXV5,Q4G176,Q9NVI7,Q96N66,P04350,Q9BSJ2,Q9BW92,Q9Y5P4,O75306 17 +Dermal translucency 0.4459361657536757 0.5760121229405548 0.5646069874738835 1.0 0.919072329328976 9 O14646,Q96L58,O14802,P02545,O75844,P41252 6 +Abnormality of the amniotic fluid 0.2775369220525964 0.5722684623546209 0.5671401122173028 1.0 0.9192538798132276 96 Q09472,Q9Y285,Q70HW3,Q9UHX1,Q6P3W7,Q15125,Q9Y5P6,P04062,P50570,P16435,P21964,Q9H6U8,Q9Y5P4,P06753,Q08AM6,Q15650,Q9UM00,Q7LGA3,P53007,P23786,P02545,P27635,Q9NVI7 23 +Abnormal spermatogenesis 0.3828053773153811 0.5706327737987859 0.5682485975503049 1.0 0.9192538798132276 16 P04062,P54132,Q01968 3 +Weakness of muscles of respiration 0.3166931951008097 0.5703979789719554 0.5684078000227832 1.0 0.9192538798132276 32 P06753,P53007,P36551,Q15650 4 +Aplasia hypoplasia involving the femoral head and neck 0.4357829600974566 0.5703862933805389 0.5684157239871572 1.0 0.9192538798132276 10 Q9NR45,P50542,Q96HY6 3 +Repetitive compulsive behavior 0.4834019130904334 0.5677568037276862 0.5702001146969089 1.0 0.9192801464871136 5 P51608,Q01082 2 +Proptosis 0.2805714019644252 0.5669518793087703 0.5707468755656073 1.0 0.9192801464871136 63 Q09472,P28340,O60568,P35240,P16435,Q32P28,O75718,Q08AM6,P02545,Q969G3,Q9H6U8,Q13409,O75431,O75844,Q9UHB7,P41227 16 +Hyperpigmentation of the fundus 0.4034040011943882 0.5663122144344337 0.5711815585973699 1.0 0.9192801464871136 2 O15484 1 +Abnormality of the musculature of the limbs 0.2518431877483014 0.5661615651490154 0.5712839549467386 1.0 0.9192801464871136 166 O15269,O60568,P35240,P62854,Q96C36,Q15125,Q9Y5P6,P50570,P46976,Q8WXH0,P42695,O60231,Q9Y487,Q7Z392,Q2TAA5,Q9Y263,P07602,O60313,O60318,P61254,O14802,P62081,O95140,Q96F07,Q13126,P51530,Q9HC21,P54886,Q06210,P42356,P41250,P36551,P06753,Q96IJ6,P08397,Q15650,O00429,Q96RR1,Q969G3,P62899,Q9BW92,Q9GZZ9,Q96BR5,Q86U42,P53007,P12235,P02545,P31483,O14979,O43819 50 +Spinal rigidity 0.3955766396881959 0.5642306916513943 0.5725971428563987 1.0 0.9197278846100104 14 P06753,Q5JTV8,P53007,Q15650 4 +Abnormal proximal phalanx morphology of the hand 0.4516382564394146 0.56373237307767 0.5729362820537129 1.0 0.9197278846100104 8 Q09472,P42345,Q08AM6 3 +Bruxism 0.4423502994481947 0.5601626894953888 0.57536847361886 1.0 0.9197278846100104 9 Q9Y5P4,P51608,Q01082,Q9NS87 4 +Optic disc pallor 0.2916963253694235 0.5592072256243085 0.5760203024162824 1.0 0.9197278846100104 48 O75380,Q6P4Q7,Q9Y6M9,O60313,Q9H0B6,O43676,O00429,Q92974,Q8IYI6,O95140,O96000,Q86Y39,Q9H061,Q10713,O43837,O75306 16 +Hemianopia 0.4505441566029114 0.5590619357078463 0.5761194514468229 1.0 0.9197278846100104 8 O00170,P00403,Q969G3,P35240 4 +Chronic noninfectious lymphadenopathy 0.444145758661877 0.5574480280784699 0.5772213587580348 1.0 0.9208527939443392 3 P49327,Q9UER7 2 +Triangular face 0.3007338937266227 0.5556504026761862 0.5784498682173735 1.0 0.9209416122132936 40 Q15233,P04062 2 +Stillbirth 0.4230355296087946 0.5538786475226363 0.5796618991206768 1.0 0.9209416122132936 11 P16435,P04062,P02545 3 +Hepatocellular carcinoma 0.3390546080086125 0.5538358968643703 0.579691158913108 1.0 0.9209416122132936 24 Q13043 1 +Heterotropia 0.2834993637706358 0.5529124644899527 0.5803233518960282 1.0 0.9209416122132936 54 P18074,P53007,P50542,Q15233,P20700,Q9UHX1,P04062,Q9H6U8,P27635,Q9NVI7 10 +Delayed closure of the anterior fontanelle 0.412750424375605 0.54996925177314 0.5823404635859297 1.0 0.9216265500888388 12 O75381,Q9UQE7,Q9Y487 3 +Delusions 0.3568949398952566 0.5499492544643194 0.5823541798016598 1.0 0.9216265500888388 19 P07602,P04062 2 +Purpura 0.3568650365336583 0.5497694398873424 0.5824775219500211 1.0 0.9216265500888388 19 P04062,P51159 2 +Hyperphosphaturia 0.4847942971381649 0.5476381286253775 0.583940403273139 1.0 0.9229961505537922 4 Q01968 1 +Incomplete penetrance 0.3197318612205891 0.546019886180976 0.585052267665015 1.0 0.9235772222472008 29 P36551,P35240,Q9UBB4,O43707,O60333,O60313,Q8WWY3,O95140,Q969G3,O14979,Q9NWH9 11 +Abnormal size of the clitoris 0.3631188687386049 0.5420184787911091 0.5878057760885045 1.0 0.9259555294207644 18 P50542,P16435,O75381,P40855,P53701 5 +Neonatal respiratory distress 0.345425970913451 0.5419176364254199 0.5878752466106771 1.0 0.9259555294207644 22 P23786,Q96EY7,Q15650,P50570,P57076 5 +Orthostatic hypotension due to autonomic dysfunction 0.4294674474431594 0.5417224473039635 0.5880097236011066 1.0 0.9259555294207644 10 P04062 1 +Retinal atrophy 0.3190300620618239 0.540781019113505 0.5886585271519091 1.0 0.9262530964955814 29 Q96PZ0,Q7LGA3,P50213,P04062,Q92620,Q10713,P51648 7 +Stridor 0.4459774301292041 0.5396910137895403 0.5894101382212595 1.0 0.926587114545188 8 Q969Y2,P53007 2 +Abnormality of the 1st metacarpal 0.4373660390120714 0.5383426546907125 0.5903405085125684 1.0 0.9269810939781544 9 Q15233,Q9UQE7,Q08AM6 3 +Abnormality of mouth shape 0.2722660539589837 0.5355016675717689 0.5923030047890208 1.0 0.9279350827830628 77 P18074,Q9UHB7,Q9UQE7,O60568,P34897,Q15233,Q86XL3,P42345,Q15125,Q03001,P04062,Q96A33,P04350,P63000,Q10713,Q01968,Q9NS87 17 +Abnormal size of pituitary gland 0.4566803662442479 0.5350755235073781 0.5925976344467441 1.0 0.9279350827830628 7 P35240 1 +Abnormal abdomen morphology 0.2427887384907175 0.5327743349451854 0.5941898020020866 1.0 0.9288891488606962 223 Q9UJW0,P14174,P36551,P53007,Q00059,Q13043,P07602,P09601,O43676,Q3LXA3,P04062,Q14108,P00374,Q15392 14 +Biparietal narrowing 0.4272206769804758 0.5316267255704294 0.594984550856942 1.0 0.9288891488606962 10 P36507,Q10713 2 +Decreased lymphocyte proliferation in response to mitogen 0.4375746714456276 0.5308189448710569 0.5955442505556148 1.0 0.9288891488606962 3 Q10469,O43909 2 +Rieger anomaly 0.4372759856630652 0.5296190591845071 0.5963760772168099 1.0 0.9288891488606962 3 Q13363,O95202 2 +Malrotation of small bowel 0.4372759856630652 0.5296190591845071 0.5963760772168099 1.0 0.9288891488606962 3 Q13363,O95202 2 +Craniofacial asymmetry 0.4372759856630652 0.5296190591845071 0.5963760772168099 1.0 0.9288891488606962 3 Q13363,O95202 2 +Preaxial foot polydactyly 0.4372759856630652 0.5296190591845071 0.5963760772168099 1.0 0.9288891488606962 3 Q13363,O95202 2 +Triangular mouth 0.4552933032033278 0.5294624530151787 0.5964846842446705 1.0 0.9288891488606962 7 P18074,Q10713 2 +Pili torti 0.4371564611985296 0.5291391657969191 0.5967089137533235 1.0 0.9289263009269334 3 P02545 1 +Ketoacidosis 0.4346775489018831 0.5266788752503041 0.5984166078001165 1.0 0.9303351421064188 9 Q4G176 1 +Cerebral visual impairment 0.2758727415476501 0.5262743473086287 0.5986976038586036 1.0 0.9304599703280207 68 Q96N67,Q9H2M9,Q96C36,Q9Y4R8,P37268,P15311,Q9Y5P4,P49591,Q12873,Q96RR1,Q96S52,P67870,P53007,P20700,P30622,P14854,P12235,P00403,Q96N66,Q9BSJ2,Q6P1N0,Q96A33,Q12904,Q9NUQ7 24 +Abnormal brainstem mri signal intensity 0.3497299010019589 0.5252882472281565 0.5993828262761487 1.0 0.9312127287587888 20 Q86Y39,Q969Y2,O75306,O43676 4 +Generalized onset seizure 0.2737155591186772 0.5245156043929058 0.5999199693577244 1.0 0.9315533140957276 113 Q6PJG6,Q9HA77,Q9Y263,P00367,P07602,P15311,Q4G176,P04062,O00429,Q96N66,Q14108,P00374 12 +Curly hair 0.397761311320264 0.5243948684901899 0.6000039249115279 1.0 0.9315533140957276 13 Q9UHB7,Q9Y5P4,Q96A33 3 +Hydrocele testis 0.4337833016888823 0.5228162214139516 0.6011021500739169 1.0 0.93284797993482 9 Q09472,Q9UBX3 2 +Inappropriate laughter 0.4535956614683529 0.5226178123616539 0.6012402424601471 1.0 0.93284797993482 7 Q96S52,P51608 2 +Tonic seizure 0.324919749713879 0.520261191146874 0.6028815411399839 1.0 0.9328708347595565 26 P07602 1 +Arthritis 0.3002934108019831 0.5189180745806973 0.6038178729273196 1.0 0.9328708347595565 38 Q01968,P14174,P21964,P04062,P02545,Q14108,O75844,Q9UBS4,Q96HY6,Q9NUQ7 10 +Onset 0.238981866188331 0.5180588742086072 0.6044171928994333 1.0 0.9328708347595565 412 Q05682,O43678,Q70HW3,P34897,P23381,P04062,Q86Y56,Q16512,Q9P0J0,P07602,O15111,P42345,Q92643,P17096,P42356,Q2TAL8,P36551,Q00059,P28288,Q96PU5,P08670,P51571,Q969G3,Q96EK5,Q14566,Q96S52,Q7LGA3,Q86XI2,P50897,Q15126,P02545,Q96N66,P51608,Q9Y3D3,Q8WXI9,Q96AX1,Q96N67,Q9UHX1,Q9NR50,Q9NXN4,Q9Y5P6,P25705,Q13409,O75431,O95235,Q6PJG6,Q9Y263,P50213,Q6NUQ1,Q5T160,P55263,Q10713,P06753,Q9H078,Q15650,Q9BW92,P41227,P35241,P51159,P12235,Q8NB49,P38435,P31483,O14979,Q9NUQ7,Q03252,P35240,Q15125,Q6ZXV5,O95630,Q92993,P50542,P51970,Q9H6U8,Q96TA2,Q4J6C6,O75306,Q8IV08,P17252,P27635,Q13813,Q01968,Q09472,Q9Y285,P50570,Q2TAA5,Q00839,Q13144,Q9HC21,Q12873,P08865,Q9UBS4,Q9UHB7,Q9Y4I1,Q86U42,P20700,P23786,Q9BSJ2,Q9NVI7 99 +Papilloma 0.4060021104911755 0.5175343933325238 0.6047831663999914 1.0 0.9328708347595565 12 P16615,Q13043 2 +Pain in head and neck region 0.4324472142639707 0.5170611158505316 0.6051134963542233 1.0 0.9328708347595565 9 Q969G3,P35240 2 +Abnormal circulating estrogen level 0.3962284924962351 0.5168234091633923 0.6052794372210408 1.0 0.9328708347595565 13 P35240,P16435,P51809,O14802,Q15031,Q969G3 6 +Iron deficiency anemia 0.4633930888979454 0.5164445764451753 0.605543939014707 1.0 0.9329683287710808 6 Q10471,O76031,P28288 3 +Mitochondrial respiratory chain defects 0.4697982027335701 0.5157534700025395 0.6060266042820945 1.0 0.9329844042220464 5 Q4J6C6 1 +Abnormality of the clitoris 0.3412794169786044 0.5155767143064052 0.6061500772111479 1.0 0.9329844042220464 22 P50542,P16435,Q08AM6,O75381,P40855,P53701 6 +Reduced subcutaneous adipose tissue 0.4402201299384278 0.5155652071454079 0.6061581159440905 1.0 0.9329844042220464 8 P02545,P41227,O75844 3 +Hemivertebrae 0.4234532536346995 0.514823360905088 0.6066764593942617 1.0 0.9331147358590042 10 Q15125,Q9UHX1,Q9UM00 3 +Abnormal bronchus morphology 0.3446875543235245 0.514623568042128 0.6068160926897632 1.0 0.9331147358590042 21 P54132,Q86Y56,P57076,P63000,Q96HY6 5 +External ear malformation 0.3718758699636824 0.5108632291170839 0.6094468306752239 1.0 0.9346329828019642 16 O75381,P50542,P41227 3 +Medial flaring of the eyebrow 0.3899671543744397 0.5070349785892909 0.6121302759449259 1.0 0.9353919998067864 2 Q9BW83 1 +Conspicuously happy disposition 0.3899671543744368 0.5070349785892792 0.6121302759449341 1.0 0.9353919998067864 2 P55795 1 +Cortical dysplasia 0.3034073189336507 0.5066611545239753 0.6123925910402033 1.0 0.9353919998067864 35 P51659,P49591,P49815,P15311,Q96PU5,P30622,P42345,Q96N66,P23258,Q6P1N0,O00139,Q12904,Q9NUQ7 13 +Myopathic facies 0.4482552329717809 0.5012723939769212 0.6161794310251589 1.0 0.9381306542635915 7 P06753,Q9Y5P4 2 +Aortic valve stenosis 0.3828540542942704 0.4987923175753396 0.6179257002548701 1.0 0.9395733511096128 14 Q09472,Q13485,Q15125,P04062,P02545,O75844 6 +Abnormal oral mucosa morphology 0.275007911507983 0.498231212193554 0.6183210854162209 1.0 0.9397805820385838 61 Q14108,P04062 2 +Renal salt wasting 0.3875783816064495 0.4967445494221669 0.619369202540538 1.0 0.940362152357714 2 Q13423 1 +Short nail 0.4582079542362469 0.4965395259089192 0.6195138076523616 1.0 0.940362152357714 6 P02545,Q9Y487 2 +Kyphoscoliosis 0.2756682284098743 0.4955908573142659 0.620183104583029 1.0 0.94044185517606 56 P53007,Q15233,P06753,P04350,P51530,Q9Y487,P41227 7 +Heteronymous hemianopia 0.4578927860617952 0.495338120733394 0.620361466348738 1.0 0.94044185517606 6 Q969G3,P35240 2 +Flat nasal alae 0.4701537628882768 0.4937931014914864 0.6214523056105716 1.0 0.94044185517606 4 P18074 1 +Global brain atrophy 0.3373634742503514 0.4909897779817439 0.6234336773755023 1.0 0.9414002443245536 22 P07602,Q9H2M9,Q9UHX1,Q96C36,Q9H6U8,Q96RP9,Q9NZJ7,O43819,O75306 9 +Abnormal urine cytology 0.2878374756946669 0.48965880256586 0.6243753587599448 1.0 0.9414002443245536 45 Q03252,P09601,P04062,Q9H6U8,Q14108,Q9UBS4,Q01968,Q8N1F7 8 +Abnormal circulating sex hormone concentration 0.3333144373626907 0.4890868744322517 0.6247801935638893 1.0 0.9414002443245536 23 P35240,P16435,Q13423,Q9NR50,P51809,O14802,Q15031,P09884,Q13144,Q969G3,Q14232 11 +Hyperactive deep tendon reflexes 0.4449893425840747 0.4883629122752123 0.6252928068546766 1.0 0.9414002443245536 7 O00429,P51608 2 +Abnormal corpus callosum morphology 0.2271208703015954 0.487918021241879 0.6256079091920761 1.0 0.9414002443245536 317 Q09472,O43678,Q96N67,P34897,Q15233,Q86XL3,Q9H2M9,Q9UHX1,P83436,Q9NR45,Q6P3W7,Q96C36,Q15125,Q6ZXV5,P04062,P51572,Q6UVJ0,Q9Y5P6,Q13409,O95630,O00139,Q8IYI6,P42695,Q92993,Q9Y4A5,Q15392,Q6PJG6,Q9HA77,Q9Y263,Q00534,P37268,P07602,P15311,P51970,O60313,P42345,Q00839,Q96F07,Q9HC21,Q9Y3B2,Q10713,P25490,P36507,Q96PU5,P51571,Q9UBX3,Q08AM6,P48651,O00429,Q9UPT5,Q969G3,Q96EK5,Q9BW92,Q9GZZ9,P53701,P41227,P18074,Q9UM00,Q9NS87,Q7LGA3,P20700,P23786,P30622,O15344,Q13813,Q96N66,Q96A33,Q9BSJ2,Q9NVI7,P63000,Q9Y3D3,Q9NUQ7 72 +Abnormal labia minora morphology 0.4447584896645776 0.4874546481669732 0.625936174506537 1.0 0.9415444857275488 7 P16435,Q9H2M9 2 +Abnormal urine alpha ketoglutarate concentration 0.4443625816098256 0.4858983180815673 0.6270392609529831 1.0 0.9426360147610215 7 P30038,P00367 2 +Abnormal metatarsal morphology 0.319905788390649 0.4855703696991928 0.6272718087872631 1.0 0.9426360147610215 26 Q03252,P50542,P16435,Q08AM6,Q96S52,Q15392 6 +Cervical spine instability 0.38489101224246 0.4852630134835068 0.6274897883585566 1.0 0.9426580229521284 2 Q96L58 1 +Abnormal circulating ige level 0.4611476389718995 0.4835599810697283 0.628698181796755 1.0 0.9429455745097884 5 P40763,P49327,Q96MG7,O95394 4 +Contractures of the joints of the upper limbs 0.2700917809629073 0.4825671114416765 0.6294031359610015 1.0 0.9433924792483682 73 P18074,P41227,Q7LGA3,P50542,O60568,P37268,P16435,P06753,P23786,P48651,P02545,P42892,P27635,O60231,P51608,Q01968,Q15392 17 +Nonketotic hypoglycemia 0.4537752871391035 0.4797343879293239 0.6314162725326289 1.0 0.9454928422032518 6 P25490 1 +Generalized hyperpigmentation 0.3789707337720886 0.4792665770554442 0.6317489962215634 1.0 0.9456856139758372 14 Q9Y4I1,Q96IJ6,P36507,Q13423,O00170,P09884,Q7Z392,P51648 8 +Smooth philtrum 0.2663498450460815 0.4724524859926507 0.6366038485608922 1.0 0.9481380127521564 78 Q9UQE7,Q9UHX1,P83436,Q96C36,Q9Y487,Q9Y4A5,Q9Y263,P42345,Q00839,Q9H6U8,Q9Y3B2,Q9Y5P4,Q2TAL8,Q01082,P67870,Q9NS87,Q7LGA3,O15344,P27635,Q9BSJ2 20 +Azoospermia 0.3711698352018202 0.4720878874784718 0.6368640577459481 1.0 0.9481380127521564 15 P04062,Q01968 2 +Irregular epiphyses 0.451213827116791 0.4701154598595335 0.6382725294317264 1.0 0.9490513990396954 6 Q9NR45,P50542,Q9NUQ7 3 +Osteosarcoma 0.322043206031553 0.469408529242326 0.6387776529497633 1.0 0.9490513990396954 25 P61254,P62081,Q13126,Q9H1A4,P62899 5 +Recurrent otitis media 0.3091182606644654 0.4680083841557447 0.6397785940317533 1.0 0.9490513990396954 29 Q9H1A4,P57076,P41227,Q12959 4 +Retinal pigment epithelial atrophy 0.4627979950746959 0.46749048164774 0.6401490004715553 1.0 0.9490513990396954 4 P51648 1 +Horseshoe kidney 0.2819890372232682 0.467264650392377 0.6403105441908579 1.0 0.9490513990396954 48 Q9UHB7,P16435,O15111,Q9UHX1,P51571,P61254,P62081,Q00839,P62899,Q92993 10 +Alopecia of scalp 0.4283799607042394 0.4670662564518109 0.6404524752610439 1.0 0.9490513990396954 8 P18074,Q15125 2 +Aplasia hypoplasia of the distal phalanges of the hand 0.2919389286788279 0.463755217870092 0.642823131055664 1.0 0.950945085414681 39 P16435,O15111,P42345,Q08AM6,P02545,Q969G3,O95630,P38435,Q96S52,P51608,Q8IWS0 11 +Abnormality of the calf musculature 0.3758236682709395 0.4636095934722172 0.6429274798051432 1.0 0.950945085414681 14 P53007,P50570,P02545,Q9Y5P6,Q7Z392 5 +Respiratory insufficiency 0.2386709393810521 0.46342867679904 0.6430571274320589 1.0 0.950945085414681 176 Q70HW3,Q969Y2,P83436,O43676,Q96EY7,Q03001,P50570,O75381,P40855,P57076,Q7Z392,Q9Y263,P50542,P07602,Q15165,O75306,P36551,P06753,Q9H078,Q15650,Q86Y39,P53701,P53007,O75380,P23786,P54132,P12235,P61960,Q01968 29 +Decreased circulating cortisol level 0.4112294226359019 0.4614587372375072 0.6444695188262497 1.0 0.9512423238042328 10 O75879,P16435,P35240 3 +Aplasia hypoplasia of the femur 0.3623646739008585 0.4603016960360999 0.6452996839734175 1.0 0.9512423238042328 16 P50542,Q9NR45,Q9UHX1,O14802,O75431,Q96HY6 6 +Delayed ability to roll over 0.4602244514729362 0.4584149922699573 0.6466543226420423 1.0 0.9512423238042328 4 P51970 1 +Congenital malformation of the right heart 0.4261941093086468 0.4582880764022065 0.6467454893686417 1.0 0.9512423238042328 8 P57076,P40855 2 +Abnormal visual electrophysiology 0.2757690305386918 0.4561491844718265 0.648282703794193 1.0 0.9522497104441464 52 O75695,P07602,O60313,P14854,P12235,Q3LXA3,P50897,Q04837 8 +Abnormal circulating creatinine concentration 0.4365965069166899 0.455716760967809 0.6485936676371344 1.0 0.9522497104441464 7 Q9H6U8 1 +Synostosis of joints 0.2987067447972026 0.455084769901286 0.649048254478003 1.0 0.9522497104441464 34 Q9UQE7,Q15233,P16435,Q9UHX1,P48651,Q9H1A4,Q9UHB7 7 +Limb girdle muscular dystrophy 0.4253122626817274 0.4547628782038977 0.649279839239419 1.0 0.9522497104441464 8 Q7Z392,P02545,O14979 3 +Somatic mosaicism 0.3774260973424898 0.4539209127926071 0.6498857509474183 1.0 0.9525356754322576 2 Q9UPY3 1 +Atrial arrhythmia 0.409192400818323 0.4527488222187515 0.6507296193821512 1.0 0.9530083295396476 10 P02545,O95235,P12235,Q9Y4J8 4 +Abnormal oral frenulum morphology 0.3671737349053885 0.4517466516996942 0.6514515059744235 1.0 0.9530083295396476 15 P17252,O15111,P02545,O75844 4 +Deviation of the hallux 0.2963784742121937 0.4507930366422468 0.6521387204722124 1.0 0.953117722804232 35 Q15233,P04062,P25490 3 +Aortic dissection 0.4577233343292634 0.4496601064364733 0.6529555409029855 1.0 0.953117722804232 4 Q13485,O15460,P31153 3 +Patellar dislocation 0.326730627470638 0.447528355597795 0.6544936191354047 1.0 0.9535304123561906 23 Q15125,Q6ZXV5,Q01968,Q96PU5 4 +Easy fatigability 0.3335428095773489 0.4469880336136275 0.6548836999443726 1.0 0.9535304123561906 21 P53007,P06753,Q969Y2,P12235,P50570,Q9Y5P6,Q96RR1,Q06210,P61978 9 +Gait ataxia 0.2688998019979109 0.4460729768986243 0.655544532124873 1.0 0.9537724400106492 67 Q03252,P48444,O14773,Q9NXN4,P49959,P04350,Q16512,Q14108,Q6PJG6,P07602,P54886,Q10713,P51659,O43681,Q8IV08,P19447,Q96RR1,Q9NZJ7,Q9GZZ9,Q96BR5,P18074,P20700,P12235,P27635,Q9NVI7,P51608 26 +Muscle fiber inclusion bodies 0.4075540884541127 0.4457837133738025 0.6557534875021438 1.0 0.9537724400106492 10 O43676 1 +Peripheral axonal degeneration 0.2667577869135132 0.444410337484937 0.65674594088649 1.0 0.9546294761716032 73 O15269,P34897,P23381,P50570,O60231,Q7Z392,P07602,O60318,O60313,O95140,Q9HC21,P54886,Q6DKK2,Q96IJ6,Q8IV08,P08397,Q9H0B6,Q15650,Q96RR1,Q9NZJ7,Q96BR5,O60333,P12235,P02545,Q9NVI7 25 +Focal segmental glomerulosclerosis 0.3296314421259587 0.4433387885282105 0.6575207035941968 1.0 0.9546294761716032 22 Q14108 1 +Abnormal myocardium morphology 0.2419816507395372 0.441736898155758 0.6586796057094801 1.0 0.9546294761716032 170 Q96AX1,O43678,P34897,Q15233,Q9H2M9,Q969Y2,P83436,O43676,Q3LXA3,Q9Y5P6,P04062,O75381,P46976,P40855,Q14108,Q9P0J0,P50542,O60313,O75306,Q8NFF5,P35573,P06753,P36507,Q08AM6,Q9H078,Q15650,Q9H061,Q86Y39,P53701,P18074,O75380,P23786,P14854,P12235,P02545,Q9NVI7,Q9Y4J8 37 +Nephrolithiasis 0.321958526966178 0.4417340452441384 0.6586816704067757 1.0 0.9546294761716032 24 Q09472,Q4J6C6,Q9H6U8,Q01968 4 +Reduced visual acuity 0.2670261737929675 0.440864906181396 0.6593108011833742 1.0 0.9551765232144132 116 P35240,Q9UHX1,O43676,P30533,P07602,O60313,Q13144,Q96TA2,Q10713,O75306,O75695,O43681,O00429,Q9H061,Q86Y39,P53701,Q9UHB7,P41227,P50897,P61960,P63000,Q01968 22 +Schizophrenia 0.3255114080298216 0.4399362580775131 0.6599832743157723 1.0 0.9552552168991322 23 P07602,P04062,P16615 3 +Hallucinations 0.2748329252125193 0.4392499228668621 0.6604804551157359 1.0 0.955639122000115 51 Q6DKK2,P36551,P07602,O60313,P50897,P04062,O00429 7 +Abnormal levels of alpha fetoprotein 0.4322175105522304 0.43900104084802 0.6606607821420123 1.0 0.955639122000115 7 Q01968 1 +Recurrent hypoglycemia 0.4542583295560296 0.4376398355626618 0.6616473893623689 1.0 0.9564372439788716 4 P25490 1 +Optic neuropathy 0.3285973878493425 0.4370622280880057 0.6620662194010296 1.0 0.9564372439788716 22 O43676 1 +Abnormal circulating fatty acid concentration 0.3344762669644661 0.4347695239705542 0.6637297281946986 1.0 0.956757771358601 20 P49748,P51659,O75648,P50542,P23786,O75880,Q08426,O75381,P40855,P09622,O75431,O43933 12 +Atrioventricular canal defect 0.4202386803086465 0.4346668674779254 0.6638042511411317 1.0 0.956757771358601 8 Q9UHX1 1 +Thin upper lip vermilion 0.2673990764181142 0.4329811386368661 0.6650284724006417 1.0 0.9568126418295678 108 Q09472,Q9UQE7,P34897,Q15233,Q86XL3,Q9UHX1,Q96C36,Q6UVJ0,Q9Y4A5,Q00534,P42345,Q92643,Q9H6U8,Q2TAL8,P35573,Q92974,Q969G3,Q9UHB7,P41227,Q9NS87,Q7LGA3,O15344,P27635,Q9BSJ2,P51608,Q01968,Q8WXI9 27 +Personality changes 0.3570160561821704 0.4325327871124112 0.665354227843195 1.0 0.9568126418295678 16 P31483,P04062,Q13144 3 +Abnormality of the epididymis 0.4524157361192683 0.4313002096589104 0.6662500979313934 1.0 0.9568126418295678 4 Q09472 1 +Recurrent fractures 0.2955012496797512 0.4304304279223679 0.6668825651954648 1.0 0.9568126418295678 34 Q32P28 1 +Abnormal cranial nerve morphology 0.2660953772292843 0.4278369919587656 0.6687698027935738 1.0 0.9568126418295678 71 Q86U42,P42356,P53007,P50542,P35240,P34897,P06753,Q9UHX1,P12235,P48651,P50570,O75381,P40855,Q969G3,Q96TA2,P51530,P51608 17 +Reduced antigen specific t cell proliferation 0.4106929510155162 0.4269072061964675 0.6694469165973298 1.0 0.9568126418295678 3 Q96MG7,O95394 2 +Abnormal t cell proliferation 0.4106929510155162 0.4269072061964675 0.6694469165973298 1.0 0.9568126418295678 3 Q96MG7,O95394 2 +Headache 0.2651901356333515 0.42667408109681 0.6696167314491555 1.0 0.9568126418295678 73 P35240,P06753,P12235,Q9Y6N5,P04062,Q4G176,O00429,Q9P2R3 8 +Nonspherocytic hemolytic anemia 0.4094982078852931 0.4224966922028021 0.672662514601231 1.0 0.9586319304939266 3 P06744,P19367 2 +Hypochromic anemia 0.385419632361147 0.4223285748094497 0.672785203875699 1.0 0.9586319304939266 12 Q10471,Q9Y606,O75027,P28288 4 +Abnormal distal phalanx morphology of finger 0.2683848774203961 0.4222670900211451 0.6728300766261879 1.0 0.9586319304939266 57 P38435,Q09472,Q7LGA3,P16435,Q9H2M9,O15111,P42345,Q08AM6,P02545,Q969G3,O95630,O75431,Q96S52,O75844,P51608,Q8IWS0,Q8WXI9 17 +Delayed eruption of primary teeth 0.4496564087242307 0.4218759384232287 0.673115573666927 1.0 0.9586319304939266 4 Q8NC56,Q92889,Q13045 3 +Decreased head circumference 0.2391978778590867 0.4215717115109527 0.6733376579574488 1.0 0.9586319304939266 483 P34897,P83436,Q96C36,O43676,Q6UVJ0,P04062,P00374,Q9Y4A5,Q15392,P07602,O15111,P16435,P21964,P61254,Q96F07,Q2VPK5,P42356,Q2TAL8,P51571,Q08AM6,P22695,Q4G176,Q92974,Q969G3,Q96EK5,Q96S52,P62899,Q9GZZ9,Q9NS87,P53007,Q7LGA3,Q86XI2,P30622,P50897,Q96N66,P61960,P51608,Q96AX1,Q86XL3,Q9H2M9,Q9UHX1,Q9NR45,Q9NR50,Q9Y5P6,O75381,P25705,Q8IYI6,Q13409,Q9Y487,Q15800,Q6PJG6,Q9HA77,Q9Y263,Q00534,P15311,P51530,Q10713,Q9H078,O00429,P41227,Q9NUQ7,Q03252,Q6ZXV5,P04350,O95630,Q92993,P50542,P51970,Q9H6U8,Q96TA2,Q9Y3B2,Q8IWS0,O75306,Q9UPT5,P53701,P51648,P18074,Q9Y606,P27635,P63000,Q13813,Q09472,Q9Y285,Q9UQE7,Q6P3W7,P51572,P40855,P23258,O00139,Q7Z392,Q2TAA5,Q9H267,P62081,Q00839,Q13144,Q9HC21,Q9Y5P4,P48651,Q86Y39,Q9UHB7,Q9UM00,O75380,P20700,P23786,P33992,P54132,Q06136,Q96A33,Q9BSJ2 109 +Adenomatous colonic polyposis 0.437928565341039 0.4213735162144345 0.6734823549652111 1.0 0.9586319304939266 6 Q13485,P28340,P20585 3 +Limb tremor 0.4378202553010783 0.4209844055096634 0.6737664692802345 1.0 0.9586725701829588 6 Q9HA77,P04350 2 +Insulin resistance 0.3407964657842759 0.416499988171874 0.6770441760299313 1.0 0.960039764393924 18 P28340,Q03252,P54132,P02545,O75431,P17096 6 +Abnormal circulating igm level 0.3405587077567813 0.415212863330146 0.677986083000043 1.0 0.960039764393924 18 P13051,P54132,Q13043 3 +Hemiparesis 0.3470882411317289 0.4146522457362069 0.6783964956621507 1.0 0.960039764393924 17 P49815,P35240,O60313,P42345,P00403,O00429,Q969G3 7 +Elevated lactate pyruvate ratio 0.4473941939155454 0.4142127342066827 0.6787183166479969 1.0 0.9600571526837522 4 Q96RP9 1 +Pollakisuria 0.4068100358422756 0.4126433844398428 0.6798679103237184 1.0 0.9600571526837522 3 P54886,Q8WVX9 2 +Arthralgia 0.2931202488292065 0.4123331245680319 0.6800952728115268 1.0 0.9600857748947133 34 P14174,Q03252,Q96HY6,Q15800,Q9NUQ7 5 +Coronal craniosynostosis 0.4410296488445266 0.4116690302476055 0.6805820275486871 1.0 0.9604804504461836 5 P16435,P09884 2 +Osteolysis 0.2978797095127131 0.4097514274910418 0.6819883005109799 1.0 0.9612945458099432 30 P04062 1 +Neoplasm of the oral cavity 0.3733616579359472 0.4078657912443778 0.6833722087860394 1.0 0.9626899482554908 13 Q969G3,Q01968,P35240 3 +Abnormal ureter physiology 0.268939733984377 0.4075197579250363 0.6836262856951771 1.0 0.9626899482554908 54 Q09472,Q9UQE7,Q86XL3,Q9UHX1,Q96C36,Q6UVJ0,P42695,O95630,Q92993,Q9Y4A5,Q00534,P16435,P21964,O14802,Q00839,P25490,O00192,Q9UHB7,Q86XI2,O60885 20 +Epileptic encephalopathy 0.3033161689544558 0.4069430109637306 0.6840498450104433 1.0 0.9627368189035868 28 Q05682,Q9HA77,Q00839,O00429,Q96F07,Q9H6U8,Q13813 7 +Rigidity 0.2665954280435452 0.4063076458873799 0.6845165681866763 1.0 0.9627927762871892 59 Q6PJG6,Q9Y263,P07602,P12235,Q96EY7,P04062,P04350,Q15392 8 +Abnormal metacarpal morphology 0.2972993361140758 0.4056121082761418 0.6850276307457466 1.0 0.9627927762871892 30 Q9UQE7,Q15233,Q32P28,P16435,Q08AM6,Q9H1A4,Q96S52 7 +Abnormality of hair pigmentation 0.3161205675588792 0.4049442119462575 0.6855185189465838 1.0 0.9628878989775844 24 P51159,Q9UM00,Q13126,P37268 4 +Neutrophilia 0.3651836369065362 0.4044013404572255 0.6859176146445511 1.0 0.9630266691375344 2 Q96BN8 1 +Skin plaque 0.4328705510708404 0.4033520556038054 0.6866892518778098 1.0 0.9635173920528364 6 P16615,Q06136 2 +Retinal dystrophy 0.2674721440253793 0.4026989704536279 0.6871696914064587 1.0 0.9635173920528364 55 Q9Y4I1,Q09472,O75695,P50542,O75381,P40855,P27635,P38435,P57076,P53701,Q10713 11 +Scaphocephaly 0.4379004290350516 0.4008949354698349 0.6884974788115825 1.0 0.9636637882237494 5 P40855,P48444,Q9NS87 3 +Fibroadenoma of the breast 0.4035244922341605 0.4007352321971931 0.6886150683212755 1.0 0.9636637882237494 3 P10644,P49327 2 +Ankyloglossia 0.411216603779157 0.3997487397613824 0.6893415893641817 1.0 0.9636637882237494 8 P02545,Q01082,Q9Y4R8,O75844 4 +Incoordination 0.2634417874151948 0.3985627596973627 0.690215406137185 1.0 0.9636637882237494 71 Q6DKK2,O43681,P53007,P07602,P06753,P12235,P04062,P27635,P31483,Q10713 10 +Hypoplasia of the iris 0.4313905286509488 0.3981376659531744 0.6905287110611078 1.0 0.9636637882237494 6 Q7LGA3,O95202 2 +Abnormal blood monovalent inorganic cation concentration 0.3149502807221263 0.3976722806499061 0.69087177269701 1.0 0.9638524039191508 24 Q99996,P36551,Q01968 3 +Pancreatitis 0.327542641172866 0.3951789217291935 0.692710847399352 1.0 0.965256233406491 20 Q13043 1 +Simplified gyral pattern 0.2947499550065239 0.3945937717718181 0.6931427107298771 1.0 0.9655677905479898 31 Q03252,Q00534,P20700,Q86XL3,Q9UPT5,Q13409 6 +Papillary thyroid carcinoma 0.3779574722970868 0.3893837767983871 0.6969922712128938 1.0 0.9662859236834324 12 P51532,Q15437,Q9UNW1,Q92785,O14497,P25054,Q969G3,Q8TAQ2,Q68CP9,Q96GM5,Q9UPY3 11 +Ptosis 0.2360134835265182 0.3885390656899588 0.6976171500772361 1.0 0.9662859236834324 235 Q09472,O43678,Q9UQE7,Q86XL3,Q9UHX1,O43676,Q15125,Q9Y5P6,P04062,O75381,P50570,P40855,O95630,Q9P0J0,P50542,P07602,P21964,O60313,P61254,P62081,Q96F07,P51530,Q9Y5P4,Q8IWS0,Q10713,Q4J6C6,O75306,Q2TAL8,P25490,P06753,P36507,Q92974,O00429,Q969G3,Q86Y39,Q96EK5,P62899,Q9GZZ9,Q9UHB7,P41227,Q9UM00,Q86U42,Q7LGA3,P53007,O75380,P33992,P12235,P02545,Q96A33,P51608 50 +Facial hemangioma 0.4342656988339249 0.3885278884726951 0.6976254198501499 1.0 0.9662859236834324 5 P16435 1 +Lacrimation abnormality 0.3351232180171024 0.3861098539033238 0.6994153123016067 1.0 0.9670156073309112 18 Q03001,Q01968 2 +Focal onset seizure 0.262641705408096 0.3855716585638387 0.6998139263578962 1.0 0.9670156073309112 95 Q6PJG6,Q9HA77,P35240,P07602,Q96PU5,P15311,Q9UBX3,Q6ZXV5,Q4G176,O00429,Q9UPT5,Q96N66,Q9NUQ7 13 +Cerebral inclusion bodies 0.3535206645213058 0.3843436337816127 0.7007237717521273 1.0 0.9671421455972848 15 P04062 1 +Corneal opacity 0.2639238200730258 0.3830370247850022 0.7016923119237726 1.0 0.9671421455972848 61 P18074,Q09472,Q01968,P50542,Q86XI2,O15111,Q08AM6,Q06136,Q03001,P04062,O75381,P40855,P02545,O75569,Q9NVI7,P53701,P51648 17 +Pelvic girdle muscle weakness 0.4065528999192158 0.3821317495281184 0.7023636428911006 1.0 0.9671421455972848 8 P06753 1 +Distal lower limb amyotrophy 0.3760287421431484 0.381019020024427 0.7031891352478317 1.0 0.9672775953365254 12 P06753,Q9H0B6 2 +Hypergalactosemia 0.3969534050179125 0.3773780848924637 0.7058926507295633 1.0 0.9672775953365254 3 Q96C23,Q9UJS0 2 +Ketosis 0.3268100123236953 0.3771101154410081 0.706091774197882 1.0 0.9672775953365254 19 Q4G176,P14854,P53985 3 +Progressive visual loss 0.3115673055641305 0.3768544494699627 0.7062817739212608 1.0 0.9672775953365254 24 Q9HA77,P35240,O60313,P50897,O00429 5 +Epispadias 0.4302125472354605 0.3749290949114179 0.707713200192323 1.0 0.9680619179076968 5 Q13485,P53701,P48651 3 +Rimmed vacuoles 0.3511302477361332 0.3729021543943199 0.7092212685139412 1.0 0.9684423026112586 15 Q86U42,P02545,O14979,P31483 4 +Abnormal lower limb bone morphology 0.229189882303732 0.372069479248854 0.7098411196619008 1.0 0.9684423026112586 184 Q09472,Q03252,O60568,Q9UQE7,Q32P28,Q9H2M9,Q9NR45,Q9UHX1,Q13555,Q6P3W7,Q15125,P04062,O75431,Q9Y487,Q9Y4A5,Q15392,Q96HY6,Q9Y263,P50542,P07602,P16435,O15111,P21964,Q9H1A4,Q9Y5P4,Q8IWS0,Q10713,Q9NWH9,O75718,Q08AM6,Q9UPT5,Q96S52,Q9UHB7,P18074,Q7LGA3,P02545,Q96A33,P51608,Q9NUQ7 39 +Generalized abnormality of skin 0.2345092447719359 0.3719530767013441 0.7099277861144953 1.0 0.9684423026112586 219 O15269,Q03252,O60568,Q9UQE7,P49257,Q969Y2,P83436,Q15125,P04062,O75381,P40855,Q14108,Q9Y487,P00374,P28340,Q9H267,P50542,Q13043,P37268,Q13126,Q9H1A4,O75306,P36551,Q00059,P36507,P48651,P17252,P53701,P51648,P41227,P18074,Q9Y4I1,P53007,P51159,P54132,Q06136,Q15126,Q8NB49,P38435 39 +Abnormal location of ears 0.2345824065804984 0.3709672138875537 0.7106619516317285 1.0 0.9690084728719688 253 Q09472,Q9UQE7,O60568,Q9H2M9,Q9UHX1,P83436,Q13555,Q96C36,Q6P3W7,Q15125,Q03001,P04062,O75381,P40855,P42892,O60231,O95630,Q9Y487,Q92993,Q9Y4A5,Q15392,Q9H267,Q9Y263,P50542,P37268,P16435,O15111,P21964,P61254,P62081,Q9H6U8,Q10713,Q4J6C6,Q2VPK5,Q2TAL8,Q12873,P25490,P06753,P36507,Q08AM6,Q9UPT5,Q96EK5,Q96S52,P62899,Q9UHB7,Q9NS87,P41227,Q9UM00,Q7LGA3,P53007,P23786,P33992,P02545,P27635,P51608,P63000,Q9Y3D3,Q01968 58 +Narrow iliac wing 0.4284103677104328 0.3689490184748916 0.7121657253321592 1.0 0.9701932262378952 5 Q15436,Q9NR45,P50542 3 +Abnormal tricuspid valve physiology 0.3166499898471048 0.3663593985415672 0.714096912097455 1.0 0.9701972175460404 22 Q96AX1,Q86XI2,Q15233,P14854,Q9H6U8,O75431,P53701 7 +Titubation 0.4020047159076453 0.36524978702617 0.7149249569724627 1.0 0.9701972175460404 8 P20700,Q6PJG6,Q01082 3 +Cardiorespiratory arrest 0.4319111910518318 0.3633704972815418 0.7163281375344963 1.0 0.9704550688515268 4 Q9Y2D4,Q96L58 2 +Increased csf lactate 0.2680080032767579 0.3628719131996433 0.7167005687552506 1.0 0.970502281143655 50 O43678,Q9P0J0,P51970,O75380,Q9Y6M9,P14854,O43676,Q5T160,Q96RP9,P30038,Q86Y39,Q9HC21,P51608,O75306 14 +Central hypothyroidism 0.3789140684407983 0.3595416676290102 0.7191899124990397 1.0 0.9723430837986434 11 P27635,P35240 2 +Abnormality of the calf 0.2607573051464903 0.3562937412435591 0.7216205959661974 1.0 0.9725407557741508 63 Q01968,Q7LGA3,P16435,Q32P28,Q9NR45,P36507,O75718,Q08426,Q13126,Q9H1A4,P17252,Q9NWH9,Q9UHB7,Q96HY6,Q9NUQ7 15 +Emg impaired neuromuscular transmission 0.4093381822471925 0.3555846081105325 0.722151672193778 1.0 0.9725407557741508 7 Q9Y5P6,O60313,P53007 3 +Abnormality of extrapyramidal motor function 0.2578835439897157 0.3552623684547948 0.7223930446632165 1.0 0.9725407557741508 75 Q6DKK2,Q9Y263,P07602,P06753,Q9H0B6,Q9H078,P12235,P04062 8 +Abnormality of digestive system morphology 0.2333115423858554 0.3546779040910525 0.7228309061176923 1.0 0.9725407557741508 259 Q9UJW0,Q09472,Q9UQE7,Q6ZXV5,P04062,Q86Y56,O75381,P50570,P40855,P42892,P57076,P08183,Q7Z392,Q15392,P28340,P50542,Q13043,P16435,P21964,P42345,P09601,P62081,Q00839,Q9H6U8,Q10713,P14174,P36551,P25490,Q96PU5,P48651,Q14566,P62899,P53701,P41227,P18074,P54132,O15344,Q96A33,P16615,Q01968 40 +Severe postnatal growth retardation 0.361248506886305 0.3536225105889384 0.7236218020435508 1.0 0.9725407557741508 13 Q9UQE7,P54132,P27635,O60885 4 +Genu varum 0.3918733972737405 0.3528954669080579 0.7241668093663947 1.0 0.972560534711979 9 Q96HY6,Q9NUQ7 2 +Ectopic calcification 0.2612309921424024 0.3519915664007286 0.7248445872963818 1.0 0.9729341909713556 57 Q96AX1,P18074,Q9Y4I1,P38435,P50542,P23786,O60313,Q15125,P04062,O75381,P40855,O00429,P02545,O75431 14 +Abnormality of hair texture 0.2610768343879004 0.3506931386289041 0.7258185736244798 1.0 0.9729341909713556 56 Q96AX1,O60568,P49589,Q15125,O75844,Q9Y487,P42345,P46778,Q9Y5P4,P36507,P19447,P62266,Q9UHB7,Q9UM00,P18074,P41227,Q96A33,Q9NVI7,Q01968,Q8WXI9 20 +Spoken word recognition deficit 0.3508510002985942 0.3497024606492941 0.7265620068111969 1.0 0.9729341909713556 2 P55072 1 +Abnormal diaphysis morphology 0.2590552486965557 0.3480495901801239 0.7278029413567637 1.0 0.973152109827768 70 Q01968,P36507,Q32P28,O75718,Q08426,Q13126,Q9H1A4,P17252,Q9Y487,Q96HY6,Q9NUQ7 11 +Upper limb muscle weakness 0.2988241877094487 0.3465929708649703 0.7288971273994191 1.0 0.9740244840516078 26 P36551,P35240,P08397,P50570,P46976,Q9Y5P6,Q8WXH0,O95140,Q969G3,P02545 10 +Hepatic fibrosis 0.2878442654398344 0.3459081990968564 0.7294117066069223 1.0 0.9740244840516078 31 Q13043,P28288,P04062,Q9H6U8,Q9NWH9,Q10713 6 +Alkalosis 0.3876941457586527 0.3455539453861754 0.7296779622759348 1.0 0.9740244840516078 3 O00170,P40818 2 +Dysphagia 0.2495123784318933 0.3413264698068649 0.7328578230929177 1.0 0.9766535890235256 143 P35240,Q15233,Q9UHX1,P04062,P04350,Q14108,Q12959,Q9HA77,Q9Y263,P07602,O60313,O75306,P25490,P06753,Q15650,O00429,P53007,P12235,O15344 19 +Abnormality of femur morphology 0.2564620294866885 0.3396192065847164 0.7341433122292316 1.0 0.9780139067513556 75 O60568,P07602,Q32P28,Q9UHX1,P04062,Q9Y487,Q96HY6,Q9NUQ7 8 +Abnormality of the incisor 0.2858048127650368 0.3391072311298804 0.7345289512006754 1.0 0.9782465434548496 32 Q12959,Q09472,Q7LGA3,Q96N67,P54132,Q8WXI9,Q9BSJ2,P41227 8 +Mania 0.3492814777464162 0.3383284446198027 0.7351156905543883 1.0 0.9786642254652904 14 O00192,P21964,P12235,P16615,P00403,Q96RR1,P51608 7 +Premature ovarian insufficiency 0.3144585462916102 0.3374737769557544 0.7357597768628106 1.0 0.9787201248889708 21 O60318,P54132,P02545,Q13144,Q9H1A4 5 +Juvenile aseptic necrosis 0.4040240076349779 0.3372345272903315 0.735940111165434 1.0 0.9787201248889708 7 Q8IWS0,Q9NUQ7 2 +Sensory neuropathy 0.281337840112849 0.3368055980357651 0.7362634527742571 1.0 0.9788693338289234 35 O15269,P35240,O60313,Q8IV08,Q9H0B6,Q03001 6 +Progressive spasticity 0.3374217943866282 0.335500086780504 0.7372478792634771 1.0 0.9793355782995644 16 P07602,O60313,Q9Y263 3 +Limited hip movement 0.337274779895896 0.3348026516303811 0.737773960132265 1.0 0.9797536749278662 16 P41250,Q7LGA3,P06753,Q03001,P02545,O75844 6 +Confusion 0.3427094527154249 0.3335276617444602 0.7387360125487419 1.0 0.9807503305200364 15 P18074,P36551,P08397,P19447,P30038 5 +Focal t2 hyperintense brainstem lesion 0.3305857831858366 0.331045910011484 0.7406098076117875 1.0 0.982113005746066 17 O75306,Q86Y39,O43676 3 +Abnormal cell proliferation 0.4110612855007565 0.3293954470233772 0.7418568087074986 1.0 0.9826423329051324 6 Q96MG7,O43909,O95394,Q10469,P00491 5 +Aplasia hypoplasia involving the metacarpal bones 0.2959620202065168 0.3287185650202524 0.7423684206115373 1.0 0.9830391310925696 26 Q9UQE7,P16435,Q32P28,Q08AM6,Q9H1A4,Q96S52 6 +Poor speech 0.2585763301745034 0.3263955907874026 0.7441250730749958 1.0 0.983286051728584 100 Q05682,Q9UQE7,Q96N67,Q15233,Q96C36,Q8WXI9,Q6UVJ0,Q16512,P04350,Q9Y487,Q7Z392,Q9Y4A5,Q9P0J0,P15311,Q9H6U8,P55263,Q10713,Q9NS87,P30622,Q96N66,Q9NVI7,P51608,P63000,Q9NUQ7 24 +Abnormality of the ureter 0.2531028997407923 0.3260236335018627 0.7444064742472709 1.0 0.983286051728584 79 Q09472,Q9UQE7,Q86XL3,Q9UHX1,Q96C36,Q6UVJ0,P42695,O95630,Q92993,Q9Y4A5,Q00534,P16435,P21964,Q00839,Q9H6U8,P25490,Q9UHB7,P41227,Q7LGA3,Q86XI2,P23786,P02545 22 +Hypoplastic nipples 0.354754136373371 0.325677420601839 0.7446684293862202 1.0 0.983286051728584 13 Q96A33,Q9UQE7,Q9H6U8,Q9NS87 4 +Defective dna repair after ultraviolet radiation damage 0.4145937421861743 0.3245216391073325 0.745543142321178 1.0 0.983286051728584 5 P18074 1 +Aplasia involving bones of the extremities 0.4194023392295004 0.3244847109402961 0.7455710955324424 1.0 0.983286051728584 4 Q08AM6 1 +Limb girdle muscle atrophy 0.3543747728522399 0.3240710164310419 0.7458842693536214 1.0 0.983286051728584 13 P06753,Q7Z392,P02545,O14979 4 +Pneumothorax 0.3999436078986178 0.3234278948630956 0.7463712067410748 1.0 0.983286051728584 7 Q9H078,P49815 2 +Erythrocyte inclusion bodies 0.418831499339527 0.3227596891810507 0.7468772437793938 1.0 0.983286051728584 4 Q9Y606 1 +Abnormality of the musculature of the thigh 0.3993236716963699 0.321352257318765 0.7479434590180873 1.0 0.983286051728584 7 P02545,O14979 2 +Sparse and thin eyebrow 0.3532854899392057 0.319474791543443 0.7493665040692308 1.0 0.983286051728584 13 Q15125,P46778,Q9UM00,P41227 4 +Abnormal nasal base 0.3531660842565468 0.3189724380658398 0.7497474131792705 1.0 0.983286051728584 13 Q969G3,P51532,Q08AM6 3 +Irregular vertebral endplates 0.3985246241375076 0.3186855941363667 0.7499649397357047 1.0 0.983286051728584 7 Q9NR45,Q9Y2D4,O14802,Q96L58 4 +Abnormality of the vertebral endplates 0.3985246241375076 0.3186855941363667 0.7499649397357047 1.0 0.983286051728584 7 Q9NR45,Q9Y2D4,O14802,Q96L58 4 +Abnormality of facial skeleton 0.224137861031515 0.3186440783832637 0.7499964246322599 1.0 0.983286051728584 344 Q09472,Q9UQE7,O60568,Q15233,Q86XL3,Q9H2M9,Q9UHX1,P83436,Q6P3W7,Q96C36,Q15125,P04062,O75381,P40855,Q86Y56,O95630,O75431,P57076,Q9Y487,Q92993,Q9Y4A5,Q12959,Q15392,Q6PJG6,Q2TAA5,Q9H267,Q9Y263,P50542,P28340,P37268,P16435,O15111,P21964,P61254,P62081,Q00839,Q9H6U8,P51530,Q9HC21,Q9Y3B2,Q4J6C6,Q2VPK5,P42356,P25490,P06753,Q96PU5,P36507,P35573,P51571,Q08AM6,P48651,Q15650,Q9UPT5,Q96EK5,P17252,P62899,P53701,Q9UHB7,P41227,P18074,Q9UM00,P53007,Q7LGA3,Q86XI2,P51608,P33992,Q9Y606,P54132,P02545,P27635,Q9BSJ2,Q9NVI7,Q01968,Q8WXI9 74 +Axonal degeneration 0.3983247371990948 0.3180200423110265 0.7504697339659747 1.0 0.983286051728584 7 Q6DKK2 1 +Erythema 0.3108350132251781 0.3177232956243584 0.7506948388203551 1.0 0.983286051728584 21 P18074,Q15125,Q9H1A4,P53701,P51648 5 +Abnormal response to endocrine stimulation test 0.3792556825302752 0.3177217372981334 0.7506960209849509 1.0 0.983286051728584 3 P16435 1 +Toxemia of pregnancy 0.3981283853667187 0.31736685929346 0.7509652508505205 1.0 0.983286051728584 7 Q09472,P02545 2 +Sensorimotor neuropathy 0.2897827348362359 0.3173423849375092 0.7509838195537739 1.0 0.983286051728584 28 P07602,O00429 2 +Vitiligo 0.4071748878923823 0.3169023850706718 0.7513176722147461 1.0 0.983286051728584 6 Q8N766,P50851,P00403,Q7Z3K3,P49327 5 +Urinary retention 0.411718143543901 0.3156033916508591 0.7523035630073496 1.0 0.983286051728584 5 P20700,P08397 2 +Abnormal mitochondria in muscle tissue 0.3129197171695038 0.3154331378043516 0.7524328097481263 1.0 0.983286051728584 20 Q86Y39,O75306,O43676 3 +Papilledema 0.2976553256530069 0.3153429425597607 0.7525012835038725 1.0 0.983286051728584 25 P04062 1 +Abnormal ldl cholesterol concentration 0.367500567876424 0.3141999990427037 0.7533691434116621 1.0 0.983286051728584 11 Q15800,P37268 2 +Abnormal blood sodium concentration 0.3597232464942672 0.3129772215517416 0.7542979679644506 1.0 0.983286051728584 12 P36551 1 +Onion bulb formation 0.3965386507311674 0.3121003776155105 0.7549642395626517 1.0 0.983286051728584 7 P50570,P02545,O95140 3 +Abnormality of the spleen 0.2555214972839594 0.309840872746224 0.756681968091437 1.0 0.983286051728584 123 P14174,Q13043,P07602,P04062,Q14108,P57076,Q15392 7 +Increased intracranial pressure 0.3093147139906341 0.3095458646715298 0.7569063290956601 1.0 0.983286051728584 21 P07602 1 +Abnormal brainstem morphology 0.2552666017957857 0.3094974561297529 0.7569431469573447 1.0 0.983286051728584 91 Q96N67,P35240,Q969Y2,Q96C36,O43676,Q9Y5P6,Q6ZXV5,Q13409,Q9Y4A5,O60313,Q9Y3B2,Q10713,O75306,Q92974,O00429,Q969G3,Q9UPT5,Q96EK5,Q86Y39,Q96S52,O75380,P20700,P63000,Q13813 24 +Convex nasal ridge 0.2884301200912116 0.3087269759768723 0.7575292217064264 1.0 0.983286051728584 28 P18074,Q09472,P28340,O14802,P02545,Q9H6U8,P51530,O75844 8 +Facial telangiectasia 0.4140959732351827 0.3086218127242435 0.7576092261866374 1.0 0.983286051728584 4 P54132 1 +Abnormality of the tarsal bones 0.2830471168819503 0.3075312847995702 0.758439014160593 1.0 0.983286051728584 30 P18074,Q9Y263,P16435,Q9UHX1,Q6P3W7,Q08AM6,Q15125,P02545,Q9UPT5 9 +Postnatal growth retardation 0.2553509493301582 0.3070858877179068 0.7587779990589971 1.0 0.983286051728584 69 Q09472,Q9UQE7,O60568,Q9H2M9,Q15125,O75431,Q9Y487,O95235,O14646,O60826,P54886,Q08AM6,Q969G3,P33991,Q9UM00,Q9NS87,P41227,P51532,P54132,O95202,P02545,P27635,O60885 23 +Abnormal csf metabolite level 0.2564157445316772 0.3068492915231915 0.7589580876609618 1.0 0.983286051728584 56 O43678,O43676,Q9P0J0,P51970,Q5T160,Q96RP9,O96000,Q9HC21,O75306,Q01082,Q9Y3Z3,P30038,Q86Y39,O75380,Q9Y6M9,P14854,P00403,P51608,O43819 19 +Ectopic kidney 0.3193579063786758 0.3055059206870008 0.7599808613305383 1.0 0.983286051728584 18 Q9UHX1 1 +Abnormality of bone marrow cell morphology 0.2562592926303164 0.3054009767826709 0.7600607779396724 1.0 0.983286051728584 56 P51159,Q9H078,P04062,Q14108,P00374 5 +Abnormal bleeding 0.2573141521021416 0.3053585936502314 0.7600930541586322 1.0 0.983286051728584 108 O60568,P35240,P49257,Q9UHX1,Q6ZXV5,P04062,P50570,Q14108,O75844,Q9Y487,P12814,Q9H267,P21964,Q4KMQ2,Q13126,O00192,Q96PU5,P36507,Q969G3,P17252,P23786,P51159,P02545,P38435 24 +Hypoplastic fifth fingernail 0.385101890276824 0.305271975172137 0.7601590184200269 1.0 0.983286051728584 8 Q969G3 1 +Nasolacrimal duct obstruction 0.3841132000784923 0.3019057885017679 0.7627238829592411 1.0 0.9835637120261714 8 Q09472,Q9UQE7,P25490 3 +Abnormal morphology of the musculature of the neck 0.3300260203618562 0.3010338699127786 0.7633886672730412 1.0 0.9835637120261714 16 Q9NXN4,Q9H6U8,P04350,O75569,P41227 5 +Hypoplastic fifth toenail 0.3776181926990009 0.3009824685231605 0.7634278631239 1.0 0.9835637120261714 9 Q14738,P51532,Q92785,O14497,Q969G3,Q8TAQ2,Q68CP9,Q96GM5 8 +Posterior embryotoxon 0.312242767976714 0.3005361879507905 0.7637681974318846 1.0 0.9835637120261714 19 Q7LGA3,P50542,P21964,O75381,P40855,P53701 6 +Abnormality of cardiovascular system electrophysiology 0.255456993781833 0.29932134653311 0.7646948686091086 1.0 0.9838214113648376 120 Q09472,Q969Y2,Q03001,P04062,O75381,P46976,P42892,Q99996,Q6PJG6,P50542,P51970,P07602,O75306,P36551,P25490,P06753,P53701,P41227,P12235,Q9Y4J8 20 +Intellectual disability progressive 0.3295168714854781 0.2987087557236942 0.7651622758082046 1.0 0.9838214113648376 16 P18074,Q9H2M9,P19447,P51608,P53701 5 +Abnormal corneal epithelium morphology 0.3237328839722808 0.2981591107685874 0.7655817280874806 1.0 0.9838214113648376 17 P18074,P02545,Q96EK5,O75844,P51648 5 +Dilatation of the cerebral artery 0.3480270136283548 0.2976335196973766 0.7659828883516666 1.0 0.9838214113648376 13 Q01082,O60568,Q9H6U8,P38435,Q9UBS4 5 +Abnormal lung development 0.2646930787486934 0.2974926176593012 0.7660904432758981 1.0 0.9838214113648376 46 O15111,Q9UHX1,Q15650,P57076,P41227 5 +Pancreatic cysts 0.4003797336768565 0.2955926472010371 0.7675411895292348 1.0 0.9840489365756452 6 Q9H6U8 1 +Agitation 0.2769348852262507 0.2948272555760302 0.7681258444524395 1.0 0.9842077776014628 34 P04062,Q15165 2 +Abnormality of lower limb joint 0.2290317336114942 0.2931842203840891 0.7693813447238069 1.0 0.9842077776014628 176 Q96AX1,Q09472,Q03252,Q9UQE7,Q15233,Q9H2M9,Q9NR45,Q9UHX1,Q86XL3,Q96C36,Q15125,Q9Y5P6,Q6ZXV5,O60231,O75431,O75844,Q9Y487,Q96HY6,P37268,P07602,P21964,P16435,Q6NUQ1,Q9H6U8,Q9H1A4,Q8IWS0,Q01082,P25490,P06753,Q96PU5,P36507,O75718,Q08AM6,P48651,P17252,Q9UHB7,Q7LGA3,P53007,P23786,Q5JTV8,P02545,Q96A33,P27635,Q01968,Q9NUQ7 45 +Abnormal vascular physiology 0.2599349214645845 0.2919596948838339 0.7703174407995541 1.0 0.9842077776014628 50 Q96AX1,O60568,P51970,P14854,Q08AM6,P04062,P25705,P02545,Q14108,O75844,Q9UHB7 11 +Ventricular fibrillation 0.399196195069886 0.2919520853535153 0.7703232589997979 1.0 0.9842077776014628 6 Q99996 1 +Impacted tooth 0.3703392927714041 0.2895941396406021 0.7721267508692395 1.0 0.9842077776014628 3 P02545 1 +Abnormal insulin level 0.2895361421984436 0.2895834591220634 0.7721349227508991 1.0 0.9842077776014628 26 O75695,P00367,P25490,P53985,P50213,Q8WWY3,P02545,O75431,O75844,Q92620,O43837 11 +Absent septum pellucidum 0.2723917257088363 0.2882447147793029 0.7731594230914476 1.0 0.9842077776014628 37 P15311,Q96N66,Q13409,Q15392,Q9NUQ7 5 +B cell lymphoma 0.4069315805198698 0.2878306701574133 0.773476358988213 1.0 0.9842077776014628 4 Q9H0U3,O95999,P49327 3 +Prominent nasal bridge 0.2558788351235502 0.2860426300094559 0.7748454709617116 1.0 0.9842077776014628 54 Q9UQE7,Q96N67,Q15233,Q9H2M9,P21964,P20700,Q15125,Q5T160,P42892,Q96EK5,P51608,P63000,Q10713,Q9Y4A5 14 +Abnormal hand bone ossification 0.3793722210724822 0.2859934051649435 0.7748831726154743 1.0 0.9842077776014628 8 Q9NUQ7 1 +Abnormality of the pulmonary vasculature 0.2646802621117113 0.2855461393377523 0.7752257609611064 1.0 0.984288720258245 44 Q7LGA3,O75718,Q86Y56,P27635,P57076,Q15392,P41227 7 +Hyperparathyroidism 0.4014460342882798 0.2847190658410469 0.7758593825309188 1.0 0.984288720258245 5 P25490 1 +Redundant neck skin 0.3787616588011365 0.2839720731118003 0.7764317824328535 1.0 0.984288720258245 8 Q9Y3D3 1 +Truncal obesity 0.3147535247365255 0.2831393186578337 0.7770700423091408 1.0 0.984288720258245 18 Q09472,Q8IWS0,Q10713 3 +Abnormal endocrine physiology 0.399455253966797 0.2789142597208707 0.7803106249610365 1.0 0.9859689444860632 5 P16435,P50336 2 +Action tremor 0.2556300601150272 0.2771057602184863 0.7816988989431308 1.0 0.9861092107626864 53 O14773,Q15233,P49959,P04350,Q14108,O75569,Q6PJG6,Q9HA77,P07602,Q9Y3C8,O14802,O95140,P54886,O75306,Q2TAL8,O43681,Q01082,P19447,Q9NZJ7,P18074,P20700 21 +Abnormality of lipoprotein cholesterol concentration 0.3504334744376807 0.2765234692578103 0.7821460362510886 1.0 0.9861092107626864 12 Q15800,P37268 2 +Hypoplasia of the brainstem 0.2774842094390475 0.2762028435026239 0.7823922733571664 1.0 0.9861092107626864 31 Q96C36,Q6ZXV5,Q9UPT5,Q13409,Q96EK5,P63000,Q10713 7 +Adenocarcinoma of the intestines 0.2869650731288092 0.2743304300738355 0.78383070136212 1.0 0.9871880281213768 26 P62081,P28340,P62899,Q13043 4 +Eclabion 0.2703129735044407 0.2733921250621251 0.7845518055866048 1.0 0.9876792945827226 37 P18074,Q2TAL8,Q96N67,P04062,Q96EK5,P27635,P51608,Q01968,P41227 9 +Abnormal circulating protein concentration 0.2419468679006276 0.2721058468382631 0.7855406339871593 1.0 0.9878155359918795 151 Q96AX1,Q9Y285,P83436,Q3LXA3,Q9Y5P6,Q6ZXV5,P50570,O75879,Q9Y487,Q7Z392,Q13043,P51530,Q9NWH9,Q8NFF5,Q2TAL8,P36551,P14174,Q00059,P35573,P06753,Q9Y6N5,Q15650,Q86U42,Q8N511,P23786,Q9Y606,P12235,Q5JTV8,P02545,Q9P2R3,P31483,P53985,O14979,Q01968,Q8N1F7 35 +Abnormal liver morphology 0.2301015106865999 0.2714944534616328 0.7860107650666706 1.0 0.9878155359918795 237 Q9UJW0,Q9Y285,Q03252,O43676,Q3LXA3,P04062,O75381,P40855,Q14108,Q7Z392,P00374,Q96HY6,Q9H267,Q9HA77,P50542,Q13043,P07602,P09601,Q9H6U8,Q9HC21,P55263,Q9NWH9,Q10713,O75306,P14174,P36551,Q00059,Q9H078,Q86Y39,Q9BW92,Q9UBS4,P53007,O75380,Q8N511,P23786,P51159,Q96A33 37 +Sparse lateral eyebrow 0.3748536052420599 0.2711877691287793 0.7862466194585926 1.0 0.9878155359918795 8 Q92643,Q92993 2 +Hyperconvex nail 0.383246398553937 0.2696401139647081 0.787437136490174 1.0 0.988181345503428 7 P42892 1 +Abnormal electroretinogram 0.2732372530744013 0.2694963744774021 0.7875477317990132 1.0 0.988181345503428 34 O75695,Q04837,P50897,Q3LXA3 4 +Abnormality of the 5th toe 0.3683831482185148 0.2692311648086465 0.7877517993232916 1.0 0.988181345503428 9 Q9Y263 1 +Postaxial foot polydactyly 0.3683831482185148 0.2692311648086465 0.7877517993232916 1.0 0.988181345503428 9 Q9Y263 1 +Leukopenia 0.2583659086849179 0.2691468138326419 0.787816706855192 1.0 0.988181345503428 49 Q14108,P04062 2 +Redundant skin 0.2859449482769429 0.2683453167412521 0.7884335271603069 1.0 0.9882395120333404 26 P36507,P38435,Q9Y487,Q9Y3D3,P41227 5 +Hypoventilation 0.3326487816546251 0.2670541323266429 0.7894274824630474 1.0 0.9882395120333404 14 O75380,P06753,P51608,O43819,O75306 5 +X linked recessive inheritance 0.2536964396886538 0.2667490549253169 0.7896623815330801 1.0 0.9882395120333404 54 Q15233,O15344,Q15125,Q8NB49,P27635,P26038,Q8IWS0,Q01968,P41227 9 +Osteomalacia 0.395186275128883 0.2666699263992544 0.78972331089023 1.0 0.9882395120333404 5 Q01968 1 +Progressive night blindness 0.3222168291501792 0.2660786731722141 0.7901786194752094 1.0 0.9882395120333404 16 O75695,P50213,Q8WWY3,Q92620,Q10713,O43837 6 +Distal sensory impairment of all modalities 0.3940620529278013 0.263492094768977 0.7921713158042212 1.0 0.9884265297049004 5 O15269 1 +Wide intermamillary distance 0.2916902152108603 0.261347697548082 0.793824386961034 1.0 0.988857095096104 24 P48444,P23786,Q9UM00,Q5SRE5,Q92974,Q9H6U8,Q96EK5,Q9Y5P4,P61978 9 +Hypoproteinemia 0.3608124253285458 0.2610678085743917 0.794040216063272 1.0 0.988857095096104 3 P49748,Q9UJS0 2 +Abnormality of the musculature of the lower limbs 0.2916186220780974 0.2609548074983203 0.7941273583739183 1.0 0.988857095096104 24 P53007,P50570,Q9Y5P6,P02545,Q8WXH0,O14979,O60231,Q7Z392 8 +Lower limb amyotrophy 0.3151298356729274 0.2585663250833759 0.7959698685005976 1.0 0.988857095096104 17 P06753,Q9NVI7,Q9H0B6,P25490 4 +Synostosis involving bones of the hand 0.3456732794426919 0.2585467952077815 0.7959849388360927 1.0 0.988857095096104 12 Q15233,Q9H1A4,P48651 3 +Aortic root aneurysm 0.2798185949544906 0.2554847626164941 0.7983487108832876 1.0 0.9893797971896082 28 Q96PZ0,Q7LGA3,P49589,P06753,P02545,Q9H6U8,Q9UBS4,Q9UHB7 8 +Omphalocele 0.3369312547246572 0.253522015843698 0.7998648505577719 1.0 0.9893797971896082 13 O15111 1 +Achilles tendon contracture 0.3572463958296883 0.2523941878100738 0.8007363922165738 1.0 0.9893797971896082 10 O60313,Q8N2K0,P02545,Q8WXH0,Q9Y3E5 5 +Abnormal cranial nerve physiology 0.2473307992552428 0.2514911462279631 0.8014344065677721 1.0 0.9893797971896082 77 P34897,P35240,Q9UHX1,P50570,O75381,P40855,P50542,P07602,Q96TA2,P51530,P42356,P06753,P48651,Q969G3,Q86U42,P53007,P12235,P02545,P51608 19 +Sensory axonal neuropathy 0.323617077733851 0.2501666068982486 0.8024585081667968 1.0 0.9893797971896082 15 P34897,Q9H0B6,Q8IV08,O95140,O60231 5 +Chronic pulmonary obstruction 0.3681777771302363 0.2499774566063368 0.802604782306426 1.0 0.9893797971896082 8 P21964,P09601,P54132 3 +Syncope 0.3283955920670225 0.2498567342017157 0.8026981432507463 1.0 0.9893797971896082 14 Q99996,P02545,Q969G3,P35240 4 +Posteriorly rotated ears 0.2525051474618187 0.2495671313667616 0.8029221197358347 1.0 0.9893797971896082 113 Q9UQE7,Q9H2M9,Q9UHX1,P04062,O75381,P42892,P40855,Q9Y4A5,Q15392,Q9Y263,P50542,P37268,P16435,Q9H6U8,Q4J6C6,Q10713,P25490,P36507,Q96S52,Q9UHB7,P41227,Q9UM00,Q7LGA3,P23786,Q01968 25 +Abnormality of chromosome stability 0.3130901852378375 0.2494707963570792 0.8029966280404985 1.0 0.9893797971896082 17 Q15126,Q969G3,P54132,P35240 4 +Steppage gait 0.2976514916470676 0.2490934856364439 0.8032884683856434 1.0 0.9893850529850804 21 O15269,O60333,P02545,P04792,O95140,P31483,O43819,Q96BR5 8 +Bilateral microphthalmos 0.3845393616584661 0.2486859631152012 0.8036037076095033 1.0 0.9894585814101744 6 P18074,Q9UHX1,Q08AM6 3 +Aplasia hypoplasia of the earlobes 0.3496876022320253 0.2484031441513242 0.8038225011255578 1.0 0.9894585814101744 11 Q09472,O00192,Q99741,P21964,O14802,Q92766 6 +Amblyopia 0.2920236205895836 0.2468635175321943 0.8050138514059908 1.0 0.9894585814101744 23 Q9UHB7,P35240,Q9UHX1,Q96TA2,P53701,Q01968 6 +Insomnia 0.3223200237353635 0.2448267854998114 0.8065905531228508 1.0 0.9894585814101744 15 P36551 1 +Abnormality of the nasal septum 0.3662594151872656 0.2440323355229053 0.8072057766987979 1.0 0.9894585814101744 8 Q15233 1 +Pituitary hypothyroidism 0.3743421043369717 0.2428407312053684 0.8081287808785669 1.0 0.9894585814101744 7 Q969G3,P35240 2 +Prolonged partial thromboplastin time 0.3743086493802035 0.2427426240427703 0.8082047855743315 1.0 0.9894585814101744 7 P38435,P49257 2 +Echolalia 0.3476474073388307 0.2412825104459619 0.8093361651608637 1.0 0.9894585814101744 11 Q9UHX1 1 +Recurrent hand flapping 0.3536439665471854 0.2406864183891832 0.8097981661306504 1.0 0.9894585814101744 3 P55795,O95714 2 +Abnormal ovarian physiology 0.2843282515590453 0.238941494780557 0.8111509491121307 1.0 0.9894585814101744 25 O00170,Q9NR50,O60318,P54132,Q15031,P02545,Q13144,Q96RR1,Q9H1A4,O75844 10 +Adrenocorticotropin deficient adrenal insufficiency 0.3177067781427208 0.2388311744580354 0.8112364959009088 1.0 0.9894585814101744 2 O00170 1 +Abnormal muscle fiber protein expression 0.3809805441688483 0.238704378183186 0.811334821585874 1.0 0.9894585814101744 6 Q9Y5P6,P02545 2 +Abnormal aortic valve physiology 0.2612098299293546 0.2370499014708276 0.8126180775188867 1.0 0.9894585814101744 40 Q15125,Q96PU5,P04062,Q9UHX1 4 +Abnormal nervous system electrophysiology 0.2243621030360893 0.2341769832073968 0.8148475830035604 1.0 0.990724729820222 198 Q09472,O15269,Q96N67,Q15125,Q9Y5P6,P50570,O75381,Q8IYI6,P40855,Q14108,Q7Z392,Q2TAA5,Q9HA77,Q9Y263,P50542,P07602,P21964,P15311,O60313,Q00839,Q96F07,Q8IWS0,P42356,O43681,P00367,P36507,Q9UBX3,Q96S52,Q9GZZ9,P18074,P53007,P30622,P20700,P50897,P02545,Q96N66,P27635,Q96A33,Q9BSJ2,P51608,Q13813,Q01968,Q9NUQ7 43 +Frontotemporal cerebral atrophy 0.3509557945041728 0.2332897092510609 0.8155364490051167 1.0 0.9910459939105172 3 Q13501,P55072 2 +Neoplasm of the tongue 0.3710517286500742 0.2332859619383085 0.8155393586645001 1.0 0.9910459939105172 7 P35240 1 +Abnormality of the metacarpal bones 0.261841592845593 0.2314908656853335 0.8169334808733268 1.0 0.9919600883522116 39 Q9UQE7,Q15233,Q32P28,P16435,Q08AM6,P48651,Q9H1A4,Q96S52 8 +Limb hypertonia 0.2578851563321721 0.2265239411527434 0.8207939407683678 1.0 0.99482371487638 42 P42356,Q9Y263,Q9BW92,Q96C36,Q15125,Q96F07,Q9HC21,Q9GZZ9,Q2TAA5 9 +Short upper lip 0.3760837070254232 0.2253160134609437 0.8217334429965428 1.0 0.9952782928063454 6 Q8N766,O95202,Q08AM6,Q13363,O96028 5 +Foot dorsiflexor weakness 0.2664611899868518 0.2247298695364849 0.8221894263649072 1.0 0.9952782928063454 34 O15269,P35240,P06753,O60318,P46976,P02545,O95140,P31483,P54886,O43819,Q96BR5 11 +Axonal degeneration regeneration 0.3788580049499911 0.2224835018892924 0.8239375150398871 1.0 0.9954271538354492 5 P02545,O95140 2 +Arnold chiari type i malformation 0.3668391591735834 0.221334394166276 0.824832071331342 1.0 0.9954271538354492 7 Q15233 1 +Spinal cord compression 0.3476963164732471 0.2209230035557512 0.8251523856769507 1.0 0.9954271538354492 10 P51530 1 +Thick upper lip vermilion 0.3415608087364284 0.2205737051737207 0.8254243770215082 1.0 0.9954271538354492 11 P41227 1 +Increased circulating androgen concentration 0.311436249626748 0.2205667510330271 0.8254297922782912 1.0 0.9954271538354492 2 O14802 1 +Adrenocorticotropic hormone deficiency 0.3114362496267457 0.2205667510330208 0.825429792278296 1.0 0.9954271538354492 2 O00170 1 +Abnormal iris pigmentation 0.2917742238655226 0.2202624512244325 0.8256667616201185 1.0 0.9954271538354492 21 P51159,O75381,P40855,P50542 4 +Blindness 0.2447354266488856 0.2201747764458215 0.8257350401112222 1.0 0.9954271538354492 76 O75695,P41227,P35240,P07602,P50897,O43676,Q13144,Q86Y39,P61960,P53701,O75306 11 +Pace of progression 0.2299171565072673 0.2198001576366218 0.8260267968588857 1.0 0.9954271538354492 168 Q05682,Q03252,P23381,P50570,P04062,P46976,P04350,Q14108,Q6PJG6,Q9P0J0,O60313,O60318,Q13126,P51530,P55263,Q10713,Q9NR28,Q00059,Q9H0B6,Q9H078,Q8IV08,O00429,Q9UBS4,Q86U42,P20700,P12235,Q5JTV8,P31483,O14979,Q8N1F7 30 +Ectopia pupillae 0.377764494919299 0.2196786215546334 0.8261214554969665 1.0 0.9954271538354492 5 Q13363,O96028,P37275,O95202 4 +Abnormal visual field test 0.3739276652689728 0.2195500529472072 0.826221594183441 1.0 0.9954271538354492 6 P35240 1 +Abnormality of the hallux 0.246775288913517 0.219148360711828 0.8265344798419321 1.0 0.9954271538354492 61 P25490,Q15233,Q9UHX1,Q15125,P04062,P41227 6 +Aplasia hypoplasia of the eyebrow 0.2537543766945545 0.2174312836711471 0.8278722534657064 1.0 0.9960301373570912 47 Q9H1A4,P25490,P36507,Q9UM00,Q08AM6,Q15125,P46778,P02545,Q92643,Q96EK5,O75431,Q9NVI7,Q92993,P41227 14 +Cystic hygroma 0.3652218073200775 0.2168306804214735 0.8283403011908861 1.0 0.9960301373570912 7 Q96S52 1 +Hypertriglyceridemia 0.2859752299332346 0.2157451674236222 0.8291863916934008 1.0 0.9960301373570912 23 P28340,Q9Y285,P35573,O14802,O95470,P22830,P02545,Q8WXH0,O75431 9 +Aplasia hypoplasia of the breasts 0.3565291310321263 0.2149389889931721 0.8298148864039123 1.0 0.9960301373570912 8 P02545,P25490 2 +Large earlobe 0.3457607350750749 0.2147756939682694 0.8299422040789179 1.0 0.9960301373570912 10 Q15392 1 +Aplasia hypoplasia of the nipples 0.2943581207468707 0.2145777522689555 0.8300965410193848 1.0 0.9960301373570912 19 Q9UQE7,Q08AM6,O60885,Q9H6U8,Q96A33,O60826,Q9NS87 7 +Soft tissue sarcoma 0.2616645003751056 0.2139303853884447 0.8306013446029503 1.0 0.9960301373570912 37 Q15392 1 +Elevated hepatic transaminase 0.2483152821168342 0.2137228538435368 0.8307631883079836 1.0 0.9960301373570912 97 Q9Y285,P83436,Q3LXA3,P40855,Q7Z392,Q2TAA5,P28340,Q9H267,Q13043,P55263,Q10713,Q00059,P28288,Q9H078,P22695,Q4G176,Q8N511,P23786,P12235,Q9Y3D3,Q01968 21 +Hypochromic microcytic anemia 0.3434886499402556 0.2134628965470375 0.8309659264204503 1.0 0.9960301373570912 3 Q15046,O75027 2 +Meningioma 0.3329312375587516 0.2129143941217345 0.8313937349084706 1.0 0.9960733484479094 12 Q09472,Q969G3,P35240 3 +Decreased number of peripheral myelinated nerve fibers 0.313737241878352 0.2106079635172071 0.8331931977047795 1.0 0.9967456313401806 15 O15269,Q9H0B6,P50570,P02545,O95140 5 +Attenuation of retinal blood vessels 0.3703804344762554 0.2102372068779467 0.8334825415330638 1.0 0.9967456313401806 6 P38435,P50213 2 +Scapular winging 0.2818115334418712 0.2088842631733733 0.8345385893485466 1.0 0.9967456313401806 24 P06753,O00429,Q9Y487 3 +Abnormality of corneal thickness 0.3085500958340029 0.2087611313174409 0.8346347154578475 1.0 0.9967456313401806 16 O75695,P50213,Q8WWY3,Q92620,O43837 5 +Abnormal pharynx morphology 0.2570575631923688 0.2078586804876074 0.835339312672627 1.0 0.997000171389104 40 Q09472,P13051,P54132,O15344,Q86Y56,P57076 6 +Impaired proprioception 0.2670970412315282 0.2072026536923551 0.835851594939613 1.0 0.997000171389104 30 P54802,P41250,O14773,P20700,Q8IV08,Q9H0B6,O14802,P18887,P35251,Q96RR1,O95140,P54886,O43819 13 +Distal upper limb amyotrophy 0.3371690586585057 0.2061398472805229 0.8366816734990548 1.0 0.997391678668454 11 P31483 1 +Paroxysmal involuntary eye movements 0.2977726986467831 0.2058295748307987 0.8369240384312329 1.0 0.997424123950436 18 O75306,Q86Y39,O43676 3 +Panhypogammaglobulinemia 0.3713757029867081 0.2036891261392791 0.8385964401440174 1.0 0.998390625708183 5 P18074 1 +Decreased circulating androgen concentration 0.3361312875104074 0.2027925844210162 0.8392971542869483 1.0 0.9986454329643012 11 P16435,P35240 2 +Bilateral ptosis 0.3160149202767297 0.2023836940855704 0.8396167748830499 1.0 0.9986454329643012 14 O00429,O60313,O75306 3 +Myopia 0.2485450789234304 0.2015848490825194 0.8402412907502832 1.0 0.9986454329643012 111 Q9UQE7,O60568,Q15233,Q9UHX1,Q3LXA3,P30533,Q9Y487,Q7Z392,Q92993,Q96TA2,O75695,P36507,Q9UHB7,P51648,P18074,Q9Y4I1,P12235,P27635,Q9NVI7 19 +Abnormal hair laboratory examination 0.3517082579533934 0.2011975045456729 0.8405441426818483 1.0 0.9986454329643012 8 P18074,P02545 2 +Persistent head lag 0.3594085723437953 0.201037708850727 0.840669088550557 1.0 0.9986454329643012 7 Q15233,P51608,Q01082 3 +Hypoplasia of teeth 0.2801455954056658 0.2003972335206394 0.8411699229384155 1.0 0.9988892834893685 24 P18074,Q09472,Q01968,P02545,O75431,O75844,P51648 7 +Decreased circulating iga level 0.3505123646148331 0.1978591721058041 0.8431552485487821 1.0 0.999850917698864 8 P13051,P54132 2 +Abnormal spinal meningeal morphology 0.3372162485065609 0.1976398535205068 0.8433268511954883 1.0 0.999850917698864 3 Q13485,P31153 2 +Renal tubular atrophy 0.3713773528533018 0.1961025146875333 0.844529928039881 1.0 1.0 4 Q96AX1,Q9NQH7,P57740 3 +Abnormal labia majora morphology 0.3336985156478869 0.1950420876551234 0.8453599990956975 1.0 1.0 11 Q9UQE7,P16435,Q9H2M9,Q08AM6,O60885 5 +Hypoplastic labia majora 0.3336985156478869 0.1950420876551234 0.8453599990956975 1.0 1.0 11 Q9UQE7,P16435,Q9H2M9,Q08AM6,O60885 5 +Autoimmunity 0.2604463327230101 0.194379155217805 0.8458790103653953 1.0 1.0 35 P14174,Q13043 2 +Abnormal circulating metabolite concentration 0.2201571545845459 0.1943606832040977 0.8458934731045518 1.0 1.0 353 Q05682,Q9Y285,Q03252,Q70HW3,P49257,O43676,Q3LXA3,Q15125,Q6ZXV5,O75381,P50570,P40855,O75879,Q99996,Q9Y487,Q7Z392,Q15800,Q15392,Q9H267,Q9P0J0,P50542,Q13043,P07602,P37268,Q08426,Q9H6U8,P51530,P55263,Q9NWH9,Q4J6C6,O75306,P14174,P36551,Q00059,P00367,P06753,Q9Y6N5,P22695,Q15650,Q4G176,Q86Y39,Q9UBS4,Q9Y4I1,Q86U42,O75380,Q8N511,P00390,P23786,Q9Y606,P14854,P51159,P12235,Q5JTV8,Q9P2R3,P31483,P53985,Q9NVI7,O14979,Q01968,Q8N1F7 60 +Abnormality on pulmonary function testing 0.2950262555896334 0.1941447143673417 0.8460625706453628 1.0 1.0 18 P06753,Q9Y285,Q7Z392,P35240 4 +Inflammatory abnormality of the eye 0.2532851054478802 0.1919686194681377 0.8477667862669465 1.0 1.0 41 P18074,P14174,Q13043,Q15800,P51648 5 +Occipital meningocele 0.3631587119980267 0.1919541813383579 0.8477780959205947 1.0 1.0 6 P21964,Q10713 2 +Proximal upper limb amyotrophy 0.3557199543013454 0.1913410782931355 0.8482583797531393 1.0 1.0 7 P02545,O14979 2 +Abnormality of the musculature of the upper arm 0.3557199543013454 0.1913410782931355 0.8482583797531393 1.0 1.0 7 P02545,O14979 2 +Deep palmar crease 0.3198331077513842 0.1912252026023806 0.8483491591190391 1.0 1.0 13 Q96AX1,P36507,P42345,O75431,Q9Y487,P61978 6 +Heterogeneous 0.2525018621027829 0.1906977175727639 0.8487624269903962 1.0 1.0 43 Q09472,P00367,P49815,P06753,P21964,O60333,P12235,O15344,P50570,P02545,Q9Y3D3,O75330,O75844,P51608,Q9NWH9,P29372,Q14790 17 +Premature graying of hair 0.3368294611299296 0.1874523956630401 0.8513059447883631 1.0 1.0 10 Q9Y4I1,Q13126,P51159 3 +Sleep wake cycle disturbance 0.3540669856459323 0.1870784222734066 0.8515991460049088 1.0 1.0 7 Q14683,Q9UBM7,Q7Z5J4,Q8N3U4,Q9Y4R8,Q9NS87 6 +Bifid scrotum 0.3606227481207326 0.1857520940280139 0.852639174029012 1.0 1.0 6 P16435,Q96EK5 2 +Hip pain 0.3637371029863894 0.1854764501706762 0.852855349831229 1.0 1.0 5 P02545,O75844 2 +Abnormal circulating free fatty acid concentration 0.366446307636598 0.1849732175929585 0.8532500423238445 1.0 1.0 4 O75431 1 +Pulmonary artery stenosis 0.3111557543133732 0.1848525088131152 0.8533447214097258 1.0 1.0 14 P41227 1 +Joint contracture of the hand 0.2476791792982365 0.18442332512693 0.8536813728387991 1.0 1.0 49 P18074,P50542,P06753,P27635,Q15392,Q01968,P41227 7 +Thin eyebrow 0.2974995616378185 0.1839042830330907 0.8540885447443725 1.0 1.0 17 Q15125,P46778,P41227,Q9UM00 4 +Hypoplastic fingernail 0.3015122901351277 0.1812987137334273 0.8561331155915126 1.0 1.0 16 O75431,O60826,Q969G3,P48651 4 +Skeletal muscle atrophy 0.2300662870912004 0.1791891243050595 0.8577892030664835 1.0 1.0 163 O15269,Q03252,O60568,P83436,P50570,P46976,Q7Z392,P50542,Q13043,P51970,O60313,Q13126,Q15165,P51530,Q9HC21,P55263,Q8IWS0,Q6DKK2,P25490,P06753,Q9H0B6,Q15650,O00429,P17252,Q6P4A7,P53007,Q9Y606,P12235,P31483,Q9NVI7,O14979 31 +Abnormality of the diencephalon 0.2622456300554186 0.1789716367372167 0.8579599726945053 1.0 1.0 30 P35240,Q969Y2,Q96EY7,Q9Y5P6,Q9UPT5,Q969G3,O43819,O75306 8 +Female hypogonadism 0.3606833882320379 0.1784750780625872 0.8583498917903949 1.0 1.0 5 P02545,O75844 2 +Nail dystrophy 0.2620523884712359 0.1778709185264699 0.8588243502742305 1.0 1.0 30 P18074,Q9H1A4,P36507,Q03001,P02545,Q969G3,O75431,O75844,P16615,Q9NS87 10 +Aplasia hypoplasia of the clavicles 0.3223204787523924 0.1778306189448342 0.8588560001520105 1.0 1.0 12 Q08AM6,P48651,P02545,O75431,P41227 5 +Abnormal blood potassium concentration 0.304956098795645 0.1776871154370594 0.8589687046147225 1.0 1.0 15 Q99996,Q01968 2 +Hydrops fetalis 0.2482924276040823 0.1766350767253301 0.8597950400330459 1.0 1.0 47 O75879,P04062,Q9HA77,P62899 4 +Postural instability 0.2841176398315577 0.1763665480080152 0.860005983514863 1.0 1.0 20 P04062 1 +Increased circulating prolactin concentration 0.3423184905898336 0.1757516437711263 0.86048906085859 1.0 1.0 8 Q969G3,O14802,P35240 3 +Amelogenesis imperfecta 0.3278371060377303 0.1754224840310144 0.860747674806124 1.0 1.0 3 Q6P4Q7 1 +Abnormality of the thoracic cavity 0.3150365497036896 0.1750695785506487 0.8610249618742731 1.0 1.0 13 P35240,O95999,Q969G3,O15460,O60885 5 +Focal white matter lesions 0.3489828451841332 0.1742912802249965 0.8616365517372706 1.0 1.0 7 P42345,P12235,P49815 3 +Abnormality of corneal stroma 0.2949790343821931 0.1739933728280211 0.8618706705091297 1.0 1.0 17 P04062,P50542 2 +Congenital diaphragmatic hernia 0.2743478627589627 0.1717149554911027 0.8636616276776339 1.0 1.0 24 O15111,P53701,Q9UQE7,Q9H6U8 4 +Mild microcephaly 0.3539611360239268 0.1700076197879506 0.8650041441627851 1.0 1.0 6 P31040,P21912,Q69YN2,Q4G0J3,Q86W42 5 +Abnormal mitochondrial morphology 0.3194323627486201 0.1687598846752535 0.865985513062606 1.0 1.0 12 P51530 1 +Sloping forehead 0.242490411324427 0.1681415180366162 0.8664719476127167 1.0 1.0 53 Q9H267,Q00534,Q86XL3,P23786,Q96C36,Q6UVJ0,Q13409,O95630,Q96EK5,Q9BSJ2,Q9HC21 11 +Color vision defect 0.3126900738257731 0.1673855787872717 0.8670666715548427 1.0 1.0 13 O00429,Q9H061 2 +Stenosis of the external auditory canal 0.3390642407528292 0.1673469233223714 0.8670970851913122 1.0 1.0 8 P16435,P61254 2 +Abnormal hypothalamus physiology 0.3389835647407883 0.1671413012713569 0.8672588693558014 1.0 1.0 8 P35240 1 +Alopecia totalis 0.3526290710485108 0.166955185394528 0.8674053107870159 1.0 1.0 6 Q9H1A4,P02545 2 +Hypoplasia of the corpus callosum 0.2207990436974827 0.1667196488204426 0.8675906443952028 1.0 1.0 200 O43678,Q96N67,P34897,Q15233,Q9H2M9,Q9NR45,Q9UHX1,P83436,Q96C36,Q15125,Q9Y5P6,P04062,Q6ZXV5,Q13409,O95630,O00139,Q9Y4A5,Q6PJG6,Q9HA77,Q9Y263,P37268,P07602,P15311,Q9Y3B2,P25490,P36507,Q96PU5,P51571,Q9UBX3,Q969G3,Q9UPT5,Q96EK5,Q9BW92,Q9GZZ9,Q9UM00,Q7LGA3,P30622,P20700,Q96N66,Q9BSJ2,P63000,Q13813,Q9NUQ7 43 +Lower limb pain 0.3523918692863147 0.1664150039815268 0.8678303671199756 1.0 1.0 6 O75569,O95140 2 +Sudden loss of visual acuity 0.2899372947148309 0.1649992491900108 0.8689445730164165 1.0 1.0 2 O00170 1 +Progressive visual field defects 0.2899372947148291 0.1649992491900066 0.8689445730164198 1.0 1.0 2 O43395 1 +Carcinoma 0.344758248215065 0.1640410230881385 0.8696988494602063 1.0 1.0 7 P28340,Q07864,P51532 3 +Abnormal labia morphology 0.2874682307047722 0.1632460839364052 0.870324683102377 1.0 1.0 18 Q9UQE7,P16435,Q9H2M9,Q08AM6,P02545,O60885 6 +Waddling gait 0.2665729679654552 0.1625291272920065 0.8708891929403388 1.0 1.0 26 P53007,P25490,P06753,Q4J6C6,Q9NUQ7 5 +Cerebellar vermis atrophy 0.317196868049822 0.1618824729073852 0.8713984053513588 1.0 1.0 12 Q96S52,P47897,Q10713,Q15334 4 +Partial agenesis of the corpus callosum 0.296219965705081 0.1616183418209799 0.87160641252478 1.0 1.0 16 P18074,Q92993,Q15392 3 +Proximal tubulopathy 0.2769421482114636 0.161359501734929 0.8718102615711882 1.0 1.0 22 Q86Y39,O75306,Q01968,O43676 4 +Abnormal respiratory system morphology 0.2147824116992283 0.1603510933250022 0.8726045128854434 1.0 1.0 325 Q9UJW0,Q09472,Q9Y285,Q9UHX1,Q96EY7,Q15125,P04062,Q14108,P57076,Q9Y487,Q96HY6,Q15392,P50542,Q13043,P07602,O15111,P13051,P09601,Q08426,Q9H6U8,Q15165,P14174,P06753,O75718,Q9H078,Q15650,Q9UHB7,P41227,P18074,Q9Y4I1,Q86U42,P53007,P20700,P51159,O15344,Q9P2R3,P27635,P26038,P63000,Q01968 40 +Abnormal circulating androgen level 0.3039954698469367 0.1602013220119015 0.8727224880304199 1.0 1.0 14 P16435,Q969G3,O14802,P35240 4 +Nephritis 0.2691424446615887 0.1601091347640912 0.8727951055064356 1.0 1.0 25 Q96AX1,Q03252,Q9P2R3,Q9H6U8,Q9UBS4,Q8N1F7 6 +Late onset 0.3221189305371985 0.1600393126253126 0.8728501063158951 1.0 1.0 11 P17096 1 +Abnormality of the sense of smell 0.2786046302312865 0.1600075662589395 0.8728751140007187 1.0 1.0 21 P04062 1 +Multiple joint dislocation 0.3207885304659402 0.1598782727203465 0.8729769641990792 1.0 1.0 3 Q9Y2D4,Q96L58 2 +Impaired vibratory sensation 0.2763689323188182 0.1588024969028995 0.8738244815330936 1.0 1.0 22 P41250,O14773,P20700,Q9H0B6,O14802,O95140,P54886,O43819 8 +Hyperorality 0.3537496265312256 0.1581797549417838 0.8743151561230391 1.0 1.0 4 Q14203,Q13501,P55072 3 +Intestinal hypoplasia 0.3529777668487758 0.1566381348944985 0.8755300462048496 1.0 1.0 4 P02545 1 +Impaired vibration sensation in the lower limbs 0.3207500042230211 0.156111490028184 0.8759451416734181 1.0 1.0 11 O43819,Q9H0B6,O14802 3 +Clonus 0.2581110965410471 0.1558299771080756 0.8761670409463023 1.0 1.0 30 Q6PJG6,P49589,Q01082,P07602,Q9Y3C8,P20700,Q9Y5P6,Q01968 8 +Hyporeflexia of lower limbs 0.3300031211459538 0.1550894898271528 0.8767507678354765 1.0 1.0 9 Q9H0B6 1 +Irregular menstruation 0.34991834969781 0.1550844911769186 0.87675470850478 1.0 1.0 5 O00170,P02545 2 +Hip subluxation 0.3338637667248066 0.1543650649753058 0.8773218975719301 1.0 1.0 8 Q03252 1 +Progressive pes cavus 0.2851597491788491 0.1541632040119355 0.8774810542469231 1.0 1.0 2 P54886 1 +Abnormal urine protein level 0.2392577753251779 0.1523789178287757 0.878888084031304 1.0 1.0 66 Q03252,P09601,Q08426,P04062,Q9P2R3,Q9H6U8,Q14108,Q9UBS4,Q01968 9 +Depression 0.2439510225826182 0.1497780777439296 0.8809397056584722 1.0 1.0 110 Q6DKK2,P36551,O43681,Q13043,P07602,P15311,P50897,P12235,P04062,Q96N66,Q15165,P51530,P17252,Q9NUQ7 14 +Constitutional symptom 0.2231171797268834 0.1489224867365962 0.881614797221715 1.0 1.0 258 Q03252,Q70HW3,P35240,P04062,Q14108,Q99996,Q15800,Q96HY6,Q9HA77,Q13043,P07602,O60313,Q9H6U8,Q15165,P51530,Q4J6C6,P14174,P36551,O43681,P25490,P06753,Q4G176,O00429,Q14566,P17252,P14854,P12235,Q9P2R3,Q9Y4J8,Q9NUQ7 30 +Enlarged kidney 0.3275204817561867 0.1487663658203558 0.8817379914406613 1.0 1.0 9 P23786,Q9UBS4,Q9H6U8 3 +Abnormal parietal bone morphology 0.3377424488390733 0.1477786749725347 0.8825174394424731 1.0 1.0 7 Q09472,Q08AM6 2 +Emotional lability 0.2384035901522122 0.147257450484027 0.8829288158693738 1.0 1.0 60 Q09472,O43678,Q9P0J0,O43681,P35240,P07602,Q13144,Q969G3,Q15165,P17252,P51608,O75306 12 +Capillary malformation 0.2998776385500764 0.146678182141784 0.8833860404493599 1.0 1.0 14 Q9UHX1,Q9UQE7,P41227 3 +Ventriculomegaly 0.2190991895862908 0.1444855909809665 0.8851170337939 1.0 1.0 198 Q03252,Q9UQE7,P34897,Q86XL3,Q9UHX1,Q96C36,Q15125,Q6UVJ0,P04062,Q86Y56,Q6ZXV5,P57076,Q9Y487,Q15392,Q9Y263,Q00534,P51970,P07602,P42345,Q00839,Q9HC21,Q10713,O75306,Q12873,P25490,P41227,P18074,Q9UM00,P53007,P20700,P23786,P14854,P63000,Q9Y3D3,Q01968 35 +Clitoral hypoplasia 0.344390193618163 0.1438606998756916 0.885610469755383 1.0 1.0 5 Q9H2M9 1 +Hypoplastic labia minora 0.344390193618163 0.1438606998756916 0.885610469755383 1.0 1.0 5 Q9H2M9 1 +Cerebral hypoplasia 0.2910932829514726 0.1433732083206521 0.8859954410184807 1.0 1.0 16 Q00534,Q86XL3,Q08AM6,Q96C36,Q6UVJ0 5 +Male hypogonadism 0.3206415115507922 0.1424453653091278 0.88672823135774 1.0 1.0 10 Q9H1A4,P09884,P51608 3 +Increased level of l fucose in urine 0.3115292712066831 0.1409724090481792 0.8878917390296985 1.0 1.0 3 Q13485,P25054 2 +Abnormal iliac wing morphology 0.2977639247463086 0.1399252833840423 0.8887190245552967 1.0 1.0 14 Q96AX1,Q09472,P50542,Q13485,Q9NR45,Q9UBN7,Q15436 7 +Abnormal eating behavior 0.2673041985009764 0.1387235008170869 0.8896686466887826 1.0 1.0 24 P53007,Q4J6C6 2 +Abnormality of the forearm 0.2373512715654019 0.137869997780093 0.8903431622341715 1.0 1.0 55 Q09472,Q9UQE7,P16435,Q32P28,P36507,P48651,Q9H1A4,Q9UHB7 8 +Primary gonadal insufficiency 0.3230136562931916 0.1376312816620918 0.8905318315971453 1.0 1.0 9 Q13144,Q9NR50,P51809,Q14232 4 +Dystrophic toenail 0.3384630366272633 0.1364922917808553 0.8914321177920681 1.0 1.0 6 P02545,Q969G3 2 +Synostosis involving bones of the upper limbs 0.2563679552774496 0.1354996474826226 0.8922168429552018 1.0 1.0 29 Q9UQE7,Q15233,P16435,P48651,Q9H1A4 5 +Cardiac arrest 0.2524606914336513 0.1346796286345714 0.8928651804202024 1.0 1.0 33 Q99996,P04062 2 +Glomerulonephritis 0.2752931885255107 0.1343371841183567 0.8931359510383587 1.0 1.0 19 Q9P2R3,Q03252 2 +Absence of pubertal development 0.3388806324724626 0.1332092988957756 0.8940278569341982 1.0 1.0 5 P02545 1 +Macroorchidism 0.3374178123132048 0.1304710060969208 0.8961937918230014 1.0 1.0 5 P51608,P38159,Q93074,Q9BZI7 4 +Inverted nipples 0.3195316209192013 0.1293331534559248 0.8970940390623605 1.0 1.0 9 Q9H6U8,Q2TAA5 2 +Abnormal intestine morphology 0.2192085285892838 0.1287197118152429 0.8975794373939943 1.0 1.0 204 Q9UJW0,Q09472,Q9UQE7,O75381,P40855,P42892,P57076,P08183,Q15392,P50542,Q13043,P09601,P62081,Q9H6U8,Q10713,P14174,P36551,Q14566,P62899,P53701,P41227,P18074,Q01968 23 +Hemorrhage of the eye 0.3050092321519887 0.1266332520438705 0.899230677470803 1.0 1.0 12 Q9Y487 1 +Upper extremity joint dislocation 0.2642622533503336 0.1251284813032925 0.9004218356730114 1.0 1.0 24 Q96PU5,Q09472,Q6ZXV5 3 +Abnormality of the columella 0.271575419094795 0.1246195697377648 0.900824734763776 1.0 1.0 20 P63000,Q9H6U8,P41227 3 +Mortality aging 0.2411188588140859 0.1226108201307197 0.9024152858734502 1.0 1.0 105 Q96AX1,O43678,Q6P3W7,P50570,P04062,O75381,Q8IYI6,P40855,O75431,O75844,O95235,Q6PJG6,Q9H267,P50542,P07602,P16435,Q6NUQ1,Q9HC21,Q00059,O75718,O00429,P18074,P51159,P02545,Q9NVI7,Q01968 26 +Lumbar hyperlordosis 0.2709950270161167 0.1223670404329852 0.9026083402349818 1.0 1.0 20 Q96AX1,P06753,Q9H2M9,Q9Y5P6,O95140,Q06210,Q96HY6,P41227 8 +Fatigable weakness of bulbar muscles 0.2847822658742568 0.1220475861612153 0.9028613316280558 1.0 1.0 16 Q15165 1 +Excessive daytime somnolence 0.2839816149813858 0.1194329395360399 0.9049323660759448 1.0 1.0 16 P41227,Q969G3,P08397,P35240 4 +Metaphyseal cupping 0.331184295635019 0.1192236978473907 0.905098132383486 1.0 1.0 5 P50542 1 +Abnormal pulmonary valve morphology 0.2872813430155154 0.118240393977854 0.905877184663491 1.0 1.0 15 O00192,P21964,O14802,P09884,Q92766,Q92993 6 +Psychotic mentation 0.3305933154448056 0.1181927335232164 0.9059149474102088 1.0 1.0 5 P00403,P30038 2 +Sporadic 0.2483179623206123 0.1166489873569605 0.9071382163792938 1.0 1.0 34 Q09472,Q03252,P48651,P04062,P04350 5 +Coarse hair 0.2690319443089684 0.1148437086130976 0.9085690037669014 1.0 1.0 20 Q96AX1,O60568,Q9Y487,Q96A33,Q9Y5P4,Q9UM00 6 +Abnormality of skeletal muscle fiber size 0.2740513529995548 0.1131508660342039 0.909910948632632 1.0 1.0 18 P06753,Q15650 2 +Abnormality of earlobe 0.2474731318237201 0.1120711254495767 0.9107670117195188 1.0 1.0 34 Q09472,Q7LGA3,Q96N67,P16435,P21964,P63000,Q8IWS0,P53701,Q15392 9 +Abnormal localization of kidney 0.2345122545797571 0.1116112971430951 0.9111316141700652 1.0 1.0 70 Q9UHB7,P16435,O15111,Q9UHX1,P51571,P61254,P62081,Q00839,Q969G3,P51530,P62899,Q92993 12 +Abnormality of the larynx 0.234409890238634 0.1114036322189834 0.9112962798979188 1.0 1.0 54 Q09472,Q01082,P16435,P07602,P21964,Q9UHX1,P02545,Q15165,P27635,Q9UHB7,Q96HY6 11 +Myalgia 0.2405427250384678 0.1095524238196152 0.9127643437477369 1.0 1.0 41 O00192,P21964,P20700,O60313,P23786,P14854,P12235,P50570,O00429,P02545,P51530,Q7Z392 12 +Paralysis 0.2350154013255025 0.1088615244649499 0.9133123242505724 1.0 1.0 52 P04062,P36551,Q15165 3 +Agenesis of corpus callosum 0.2384080819641927 0.107097658155528 0.9147115050044894 1.0 1.0 98 Q09472,Q9H2M9,Q86XL3,Q9UHX1,Q96C36,Q6P3W7,Q6UVJ0,Q9Y5P6,P42695,Q13409,Q92993,Q15392,Q00534,Q00839,Q9HC21,Q10713,P25490,Q08AM6,P48651,Q969G3,P53701,Q9NS87,P18074,Q7LGA3,P23786,O15344,Q9Y3D3 27 +Macular thickening 0.3123335618996312 0.1065927255662901 0.9151120898620224 1.0 1.0 8 P50213,P35240 2 +Muscle weakness 0.2142075079252597 0.1053579810033776 0.9160917567393771 1.0 1.0 299 O15269,Q70HW3,P35240,Q15233,Q9UHX1,O43676,P50570,P46976,O75381,P40855,Q7Z392,P00374,Q9P0J0,Q9Y263,P50542,P51970,P07602,O60313,O60318,Q08426,Q13126,Q15165,Q96TA2,P51530,Q9HC21,Q10713,Q4J6C6,O75306,Q6DKK2,P36551,O43681,P25490,P06753,P36507,P48651,Q15650,Q86Y39,P17252,Q86U42,P53007,O75380,P20700,P23786,Q9Y606,P14854,P12235,Q5JTV8,P31483,O14979 49 +Corneal neovascularization 0.3212442927469482 0.1044150086733259 0.9168400125872088 1.0 1.0 6 P18074,P21964 2 +Hyperthyroidism 0.3066581731772911 0.1009766066499056 0.9195690304325894 1.0 1.0 9 O00192,P21964,P12235,O14802,Q96RR1 5 +Aplasia hypoplasia of the ear 0.2317037355819398 0.1003583349177556 0.9200598466320892 1.0 1.0 56 O15111,P04062 2 +Renal hypoplasia aplasia 0.2340002389478984 0.0992504855555092 0.9209393910266844 1.0 1.0 87 Q2VPK5,P41227,Q7LGA3,O75306,Q00534,P16435,P21964,Q86XL3,Q9UHX1,P33992,Q96C36,P61254,P62081,Q6UVJ0,P62899,Q9Y4A5,Q15392 17 +Mixed hypo and hyperpigmentation of the skin 0.3187453374303319 0.0983355536945946 0.92166584721497 1.0 1.0 4 P02545 1 +Abnormal serum interleukin level 0.2861409796893586 0.0978775994859781 0.9220294875855888 1.0 1.0 3 P09884,P49327 2 +Anophthalmia 0.301512590608439 0.0970447771761119 0.922690835193205 1.0 1.0 10 P53701,Q96N67,P41227 3 +Renal tubular acidosis 0.276391512493971 0.0956770214439708 0.9237770913913176 1.0 1.0 16 Q08426,Q9H267,Q01968,O75306 4 +Complete duplication of phalanx of hand 0.316195811446727 0.0949512502405124 0.9243535485659088 1.0 1.0 5 P41227 1 +Radial deviation of the hand or of fingers of the hand 0.2876926304398139 0.0948062832708791 0.9244686960269792 1.0 1.0 13 P41227 1 +Abdominal obesity 0.3146292622871155 0.0935279742725266 0.9254841268364596 1.0 1.0 6 O00170,P54132 2 +Increased muscle lipid content 0.2996955476806185 0.0931768337994101 0.925763078260228 1.0 1.0 10 P06753 1 +Abnormal jaw morphology 0.2106317230673024 0.0929237771569825 0.925964116032432 1.0 1.0 308 Q09472,Q9UQE7,Q86XL3,Q9H2M9,Q9UHX1,P83436,Q6P3W7,Q96C36,Q15125,P04062,O75381,P40855,O95630,O75431,Q92993,Q9Y4A5,Q12959,Q15392,Q6PJG6,Q2TAA5,Q9H267,Q9Y263,P50542,P28340,P37268,O15111,P21964,P61254,P62081,Q00839,Q9H6U8,P51530,Q9HC21,Q9Y3B2,Q4J6C6,Q2VPK5,P42356,P25490,P06753,Q96PU5,P51571,Q08AM6,P48651,Q15650,Q9UPT5,Q96EK5,P17252,P62899,P53701,Q9UHB7,P41227,P18074,Q9UM00,P53007,Q7LGA3,Q86XI2,P51608,P33992,Q9Y606,P54132,P02545,P27635,Q9BSJ2,Q9NVI7,Q01968,Q8WXI9 66 +Spastic dysarthria 0.3040779224048158 0.0908412710858473 0.9276187160186192 1.0 1.0 8 Q9H2M9,O14802 2 +Abnormality of mouth size 0.234989789179852 0.0907737501182863 0.9276723682910816 1.0 1.0 132 Q09472,Q15233,P83436,Q6P3W7,P04062,O75431,Q9Y487,Q92993,Q9Y4A5,Q15392,P28340,P16435,P21964,P42345,Q9H6U8,Q2TAL8,P51571,P48651,Q15650,Q969G3,Q9UM00,Q7LGA3,P33992,P02545,P27635,Q9NVI7,P51608,Q8WXI9 28 +Foot acroosteolysis 0.3123813277171232 0.0900074490032047 0.9282812954092624 1.0 1.0 6 O75431,P02545 2 +Osteolysis involving bones of the feet 0.3123813277171232 0.0900074490032047 0.9282812954092624 1.0 1.0 6 O75431,P02545 2 +Lung adenocarcinoma 0.3116223483716721 0.0886371249886246 0.929370302715584 1.0 1.0 4 Q99496,Q14790,P30154 3 +Vascular skin abnormality 0.2380019026298256 0.0876386829351732 0.9301638559125676 1.0 1.0 116 Q9UQE7,O60568,P49257,Q15125,P04062,Q14108,Q9Y487,P28340,Q13043,Q13126,Q9H1A4,O75306,P48651,P17252,P53701,P51648,P18074,P51159,P54132,Q06136,P38435 21 +Scleroderma 0.3109784837576674 0.0874064636981888 0.930348431756485 1.0 1.0 5 P28340 1 +Abnormal nipple morphology 0.2308449301411464 0.0874019394904639 0.930352027789773 1.0 1.0 61 Q9UQE7,P48444,Q15233,Q9H2M9,P83436,Q9Y4A5,Q2TAA5,Q9H6U8,O60826,Q9Y5P4,Q08AM6,Q92974,P19447,Q96EK5,Q9UM00,P18074,Q9NS87,Q7LGA3,P23786,Q96A33,O60885 21 +Abnormality of vitamin metabolism 0.2526776074832401 0.0859098571317365 0.93153807562548 1.0 1.0 25 Q13043 1 +Wrist flexion contracture 0.3085814062118956 0.0840935656092606 0.9329820404244356 1.0 1.0 5 P51608 1 +Abnormalities of placenta or umbilical cord 0.2722996489390884 0.0836506843924776 0.9333341678001554 1.0 1.0 16 Q2TAL8,Q01082,P16435,P02545,O75844 5 +Photophobia 0.2410820790011193 0.0832530564112006 0.9336503262088214 1.0 1.0 35 P18074,O75695,P07602,Q6P4Q7,P50213,O43395,O43837,Q8WWY3,P19447,Q9NZJ7,Q92620,P51648 12 +Microdontia 0.2519339516775616 0.0828551540336017 0.9339667132700648 1.0 1.0 25 Q9UQE7,Q96A33,Q9H1A4,Q9Y487,Q9UM00 5 +Cubitus valgus 0.2745484800796676 0.0813332757047745 0.9351769114557872 1.0 1.0 15 P36507,P50542 2 +Dysmetric saccades 0.3062281326691071 0.080830020531223 0.9355771332443246 1.0 1.0 6 P49959,O14773 2 +Abnormality of prothrombin 0.274261120060538 0.0805587991231845 0.9357928331986334 1.0 1.0 15 Q13043 1 +Neonatal hypotonia 0.2294864388988764 0.0805527312052138 0.935797659013355 1.0 1.0 58 Q15233,P06753,Q9UM00,P23786,Q9H078,Q08AM6,Q03001,P27635,P51608,Q9Y3D3,Q01968,Q2TAA5 12 +Ventricular tachycardia 0.2742478038727236 0.0805229728912879 0.9358213258324066 1.0 1.0 15 Q99996,P46976,P41227 3 +Chronic lung disease 0.2928686316311542 0.0793321625493711 0.9367684248950878 1.0 1.0 10 Q9UHB7 1 +Functional motor deficit 0.229326665861428 0.078996612054287 0.9370353178325316 1.0 1.0 146 Q9Y285,P35240,P23381,Q9H2D1,Q969Y2,Q9NXN4,Q96C36,P50570,P04062,P46976,Q7Z392,P07602,Q96F07,P51530,Q9HC21,Q8NFF5,O43681,P06753,Q9H0B6,Q92974,O00429,Q969G3,Q9GZZ9,P53701,P53007,P20700,P23786,Q9Y606,P12235,P27635,P31483,P51608 32 +Broad toe 0.2423353939500537 0.0788226458659351 0.937173691289772 1.0 1.0 32 Q09472,Q9UHX1,Q96C36,Q15125,P41227 5 +Periventricular heterotopia 0.2892895107717188 0.0785032258183116 0.9374277643119816 1.0 1.0 11 Q96PU5 1 +Thoracic kyphoscoliosis 0.3033929193040757 0.0768252176104744 0.938762589268507 1.0 1.0 6 P02545,Q96C36 2 +Limitation of neck motion 0.3005676725425686 0.0751706537788758 0.9400789331660232 1.0 1.0 4 P02545,O94905,Q9UHD2 3 +Aplastic anemia 0.2946338884082375 0.0745486053912087 0.9405738672216029 1.0 1.0 8 Q9H1A4 1 +Metaphyseal irregularity 0.2865147920468508 0.0728331569933495 0.9419388855491788 1.0 1.0 11 Q2TAL8,P50542,Q96HY6 3 +Laryngeal stenosis 0.2995803002499108 0.0724999386019299 0.942204054330602 1.0 1.0 5 Q96HY6 1 +Polyphagia 0.2884789794450241 0.0710007347006583 0.9433971707616312 1.0 1.0 10 Q4J6C6 1 +Turricephaly 0.2818132480959844 0.0702823391415017 0.9439689390665464 1.0 1.0 12 P50542,P16435,P21964,O00192,O94855,Q92766 6 +Dysphonia 0.2379559789386552 0.069843437198445 0.9443182736864056 1.0 1.0 36 Q6DKK2,P18074,P42356,P53007,Q15233,P20700,P08397,P19447,O95140,Q96RR1,P04350,O75569,P54886 13 +Anisocoria 0.2945921720944088 0.068667220929555 0.945254510502714 1.0 1.0 4 P26196,Q96IJ6,Q96ST3 3 +Fulminant hepatic failure 0.292799521959959 0.0668190344286735 0.9467257699907404 1.0 1.0 4 P40939,Q96RP9,P98170 3 +Severe infection 0.2889156298764673 0.0655636087328599 0.9477252627707862 1.0 1.0 8 P54132 1 +Focal t2 hyperintense basal ganglia lesion 0.2548696367889124 0.0650248678855072 0.9481542004417038 1.0 1.0 20 Q9P0J0,O75306 2 +Hepatitis 0.255447879751876 0.064846841274291 0.9482959459640564 1.0 1.0 19 Q9H267,Q13043 2 +Cutaneous cyst 0.2892142216910616 0.0632620048154083 0.9495578708974124 1.0 1.0 4 Q9H488,P49815,P25054 3 +Epidermoid cyst 0.2892142216910616 0.0632620048154083 0.9495578708974124 1.0 1.0 4 Q9H488,P49815,P25054 3 +Iris hypopigmentation 0.2870638163345781 0.0627937367860322 0.949930753348832 1.0 1.0 8 P51159 1 +Dysplastic corpus callosum 0.2735156227541889 0.0613765858483034 0.9510592989833 1.0 1.0 13 P20700,Q92993,Q15233 3 +Abnormality of retinal pigmentation 0.2283085716436159 0.0607741254657013 0.951539097107542 1.0 1.0 71 Q96AX1,O43678,Q9H2M9,Q9Y5P6,O75381,P40855,O60231,Q92620,Q9P0J0,P50542,Q6P4Q7,P50213,O14802,O75306,O75695,Q8WWY3,P19447,P53701,P51648,P18074,Q86XI2,O43395,P02545,O43837 24 +Meningocele 0.282282322627311 0.0599911195612227 0.9521627075161188 1.0 1.0 10 P21964,Q9Y5P6,Q10713 3 +Thin vermilion border 0.2279274818793721 0.0590384132992543 0.9529215120685182 1.0 1.0 145 Q09472,Q9UQE7,P34897,Q15233,Q86XL3,Q9UHX1,Q96C36,Q6P3W7,Q6UVJ0,P42695,Q9Y4A5,Q96HY6,Q6PJG6,Q00534,P42345,Q00839,Q92643,Q9H6U8,Q2TAL8,P35573,Q08AM6,Q92974,Q969G3,Q9UHB7,Q9NS87,P41227,Q7LGA3,O15344,P02545,P27635,Q9BSJ2,P51608,Q01968,Q8WXI9 34 +Mildly elevated creatine kinase 0.2491874312957825 0.057623904051819 0.9540482086268884 1.0 1.0 23 Q2TAL8,P06753,Q15650,P50570,P31483 5 +Pulmonic stenosis 0.237719580304003 0.0571687517612234 0.9544107699173284 1.0 1.0 32 Q09472,Q9UQE7,P36507,P55263,O14802,O60826,O95235,O43819,O75306 9 +Abnormal aortic arch morphology 0.2710911368220845 0.056221659220445 0.9551652268872152 1.0 1.0 13 Q09472,Q9UHX1,P21964 3 +Dry skin 0.2348839760593625 0.0545933632088657 0.9564624262671118 1.0 1.0 36 P18074,P37268,P36507,Q15650,P51648,Q2TAA5 6 +Sound sensitivity 0.2789275819233912 0.0543931445448532 0.9566219406316072 1.0 1.0 10 P17900,Q09472,Q13045 3 +Dyslexia 0.2834928229665071 0.0541797425035346 0.9567919601153954 1.0 1.0 7 Q13501,Q01082,P55072,P25054,P48506,Q96T60 6 +Abnormal pupil morphology 0.2693229478729803 0.0525647344115156 0.9580787159684718 1.0 1.0 13 P26196,P37275,P61586,Q96IJ6,O95202,Q13363,O96028,O95163,Q9NRG9,P11047,Q96ST3,Q01968 12 +Microphallus 0.280932456664669 0.052546208333295 0.9580934772402838 1.0 1.0 5 Q96ST3,Q9Y4A5,Q96GM8,Q9UNW1 4 +Limitation of movement at ankles 0.2805254070511901 0.0521687218972612 0.9583942552929988 1.0 1.0 5 P02545 1 +Abnormality of upper limb joint 0.234114821759974 0.0511063283245143 0.9592407933108738 1.0 1.0 120 Q09472,Q9UQE7,O60568,Q15233,Q9NR45,Q15125,P42892,O60231,Q15392,P50542,P37268,P16435,P61254,Q9H1A4,P06753,P36507,P48651,P41227,P18074,Q7LGA3,P23786,P02545,P27635,P51608,Q01968,Q9NUQ7 26 +Retinal telangiectasia 0.2813105778367507 0.0502744547242941 0.959903680197462 1.0 1.0 6 O75306 1 +Ventricular escape rhythm 0.2779438135086594 0.0498297095647246 0.9602580912754493 1.0 1.0 5 P02545,Q13642,Q8WXH0,P50402 4 +Sparse eyebrow 0.2317268581214633 0.0488385187563208 0.9610479852572322 1.0 1.0 39 P25490,Q9UM00,Q08AM6,Q15125,P46778,P02545,Q92643,Q96EK5,O75431,Q9NVI7,Q92993,P41227 12 +Squamous cell carcinoma 0.2563119125506231 0.0483351809654753 0.9614491169534644 1.0 1.0 17 P18074,P54132,P02545,P19447,Q9H1A4 5 +Small hand 0.2356631794178421 0.0479356098236326 0.9617675594643448 1.0 1.0 32 O15111,Q9UQE7,Q9UHB7,Q96EK5 4 +Myotonia 0.2781100478468831 0.0478720835607544 0.9618181879647554 1.0 1.0 7 Q00577,P02545,Q8WXH0,P08237,P50402,Q13642 6 +Lack of skin elasticity 0.258762283815996 0.0477950567810631 0.9618795761731782 1.0 1.0 16 P28340,Q15334,P02545,P17252,O75844 5 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.2780269058296076 0.0469963066010287 0.9625161711833672 1.0 1.0 6 Q15149,P02545,Q8WXH0,P50402,Q13642 5 +Phthisis bulbi 0.2744203538781743 0.0467884748302111 0.9626818147276096 1.0 1.0 5 Q9UQE7 1 +Head titubation 0.2772224666088935 0.0462183060278316 0.963136251965072 1.0 1.0 6 P20700,Q01082 2 +Broad distal phalanx of finger 0.273893714225517 0.0450133552803552 0.964096663770632 1.0 1.0 8 Q09472,Q7LGA3 2 +Abnormal vitreous humor morphology 0.2712195515492455 0.0449392357781594 0.9641557427923392 1.0 1.0 11 P35240 1 +Duodenal adenocarcinoma 0.2662085449656338 0.0445853903673774 0.9644377878775696 1.0 1.0 4 Q13485,P43246,P25054 3 +Skin rash 0.2452154865148352 0.0440394809002457 0.9648729331738992 1.0 1.0 23 P18074,P14174,P54132 3 +Abnormality of the achilles tendon 0.2700203392123818 0.0429884045301392 0.965710777154326 1.0 1.0 11 P02545,O60313,Q8WXH0 3 +Heat intolerance 0.2737482014226921 0.0429696189240537 0.9657257520622068 1.0 1.0 6 P36507 1 +Facial edema 0.2375961151849453 0.0428475693467007 0.9658230439299936 1.0 1.0 28 Q9H1A4,Q9P2R3,P50542 3 +Abnormality of the knee 0.229046286591344 0.0425902186550075 0.9660281927991295 1.0 1.0 90 Q09472,Q86XL3,Q15125,Q9Y5P6,Q6ZXV5,O60231,O75431,Q96HY6,P37268,P21964,Q9H1A4,Q01082,P25490,P06753,Q96PU5,P36507,P48651,P17252,Q7LGA3,P23786,P27635,Q01968,Q9NUQ7 23 +Abnormal shoulder morphology 0.2362719599148326 0.0425430893925772 0.96606576245795 1.0 1.0 29 Q96PU5,P41227 2 +Hypoplastic female external genitalia 0.2583327584244699 0.0416749529091183 0.9667578212921232 1.0 1.0 15 Q9UQE7,P16435,Q9H2M9,Q08AM6,O60885 5 +Vocal cord paresis 0.2602330445174732 0.0408111675094108 0.9674464363921792 1.0 1.0 4 O95140,P43243,P36776 3 +Peripheral hypomyelination 0.2602330445174693 0.0408111675094085 0.9674464363921812 1.0 1.0 4 Q9Y5B0,P19367,O60231 3 +Simple ear 0.2664793957415448 0.0405508425705516 0.9676539738385868 1.0 1.0 5 P16435 1 +Truncal ataxia 0.2531451085466159 0.0403193047621903 0.9678385633175564 1.0 1.0 17 P34897,P14854,O14802,P51608,Q7Z392 5 +Volvulus 0.2706388220265454 0.0402127452962066 0.9679235165727113 1.0 1.0 6 Q9UQE7 1 +Abnormal shape of the occiput 0.2342123195521818 0.0401086173699751 0.9680065316636572 1.0 1.0 30 O15111,O75381,P50542,Q01968 4 +Palpebral edema 0.2703259870938785 0.0396152440963688 0.9683998739479832 1.0 1.0 7 Q01082,P50542 2 +Chronic otitis media 0.2383664831771696 0.0389927656488957 0.9688961564048072 1.0 1.0 26 P57076,Q86Y56,Q01968 3 +Skin appendage neoplasm 0.2665270714926683 0.0364808666394962 0.9708989347631508 1.0 1.0 8 Q09472,P43246,Q15437,P35222,P25054,Q92793,Q9UPY3 7 +Biconcave vertebral bodies 0.2661483253588503 0.0355894766273469 0.9716096994422329 1.0 1.0 7 Q14807,P40818,O00170,P32322,Q9NR45,Q96AY3 6 +Highly arched eyebrow 0.2243569007271388 0.0354197290909834 0.9717450530418724 1.0 1.0 65 Q9UHB7,Q09472,Q2VPK5,Q9UQE7,P34897,Q9UHX1,Q13555,Q96F07,Q96EK5,Q96S52,P63000,Q10713,Q9Y4A5,Q9UM00 14 +Lower extremity joint dislocation 0.223751855489992 0.0333887963857494 0.9733645438717398 1.0 1.0 81 Q09472,P53007,Q9UQE7,P06753,Q96PU5,P21964,Q9UHX1,Q96C36,Q08AM6,Q15125,Q9Y5P6,P02545,Q6ZXV5,Q9H6U8,Q96A33,Q9Y487,Q01968 17 +Carpal bone hypoplasia 0.2545618476851184 0.0326862503331506 0.9739247886779754 1.0 1.0 5 Q9NR45,P54886 2 +Aplasia hypoplasia involving the carpal bones 0.2545618476851184 0.0326862503331506 0.9739247886779754 1.0 1.0 5 Q9NR45,P54886 2 +Abnormal cerebral cortex morphology 0.2168239790698847 0.0319918487025707 0.9744785513647504 1.0 1.0 240 Q03252,Q96N67,Q9UQE7,P34897,Q9H2M9,Q86XL3,Q96C36,Q6P3W7,P51572,Q6UVJ0,P04062,Q9Y5P6,O75381,Q6ZXV5,Q13409,P40855,P23258,O00139,Q9Y487,Q92993,Q9Y4A5,Q15392,Q9H267,Q9Y263,P50542,Q00534,P37268,P15311,P51970,P42345,Q9HC21,Q10713,O75306,Q2VPK5,P42356,P36507,Q96PU5,Q08AM6,Q969G3,Q9UPT5,Q96EK5,Q96S52,Q9UM00,P18074,Q9Y4I1,Q7LGA3,P30622,P20700,P23786,Q96N66,Q9BSJ2,P51608,P63000,Q9NUQ7 54 +Abnormal natural killer cell morphology 0.2528392109981995 0.0316878954837486 0.974720948045032 1.0 1.0 5 O95394,Q13546,Q7L590,P33991 4 +Reduced natural killer cell count 0.2528392109981995 0.0316878954837486 0.974720948045032 1.0 1.0 5 O95394,Q13546,Q7L590,P33991 4 +Abnormal proportion of cd8 positive t cells 0.2585529570545167 0.0307818158701871 0.9754435423814842 1.0 1.0 6 P54132,Q96MG7,O95394 3 +Abnormal joint morphology 0.2146425098830421 0.0300345585297807 0.9760394918740928 1.0 1.0 279 Q96AX1,Q09472,O15269,Q03252,O60568,Q9UQE7,Q15233,Q9H2M9,P49257,Q9NR45,Q9UHX1,Q86XL3,Q96C36,Q15125,Q9Y5P6,P04062,Q6ZXV5,P42892,O60231,Q14108,O75431,Q9Y487,Q96HY6,Q15392,P50542,P37268,P07602,P16435,O15111,P21964,P61254,Q9H6U8,Q9H1A4,Q8IWS0,P14174,P25490,P06753,Q96PU5,P36507,P51571,O75718,Q08AM6,P48651,P17252,Q9UBS4,Q9UHB7,P41227,P18074,Q7LGA3,P53007,P23786,Q5JTV8,P02545,Q96A33,P27635,P38435,P51608,Q01968,Q9NUQ7 59 +Small earlobe 0.2590012077822823 0.0287515066712825 0.977062776943296 1.0 1.0 8 O00192,P21964,Q99741,Q92766 4 +Emg abnormality 0.2240080776393815 0.0286622451470511 0.9771339679955569 1.0 1.0 74 O15269,O14773,P50570,P46976,Q9Y5P6,Q8WXH0,O60231,Q99986,P07602,Q13485,O60313,O95140,Q06210,O43681,P06753,Q15650,Q96RR1,P53007,Q9Y606,P12235,P02545,P31483,O43819 23 +Ileus 0.2331566557154132 0.0283178365393211 0.9774086548030634 1.0 1.0 4 P08397,P50336 2 +Mitral valve prolapse 0.2373250320414707 0.0282641109736942 0.9774515044509772 1.0 1.0 25 P06753,P53701,Q9UBS4,Q9H6U8 4 +Craniofacial hyperostosis 0.2600206118331417 0.0280815009150916 0.9775971483864055 1.0 1.0 9 P18074,P19447,P48651 3 +Tracheomalacia 0.2559365463958502 0.0276406832029496 0.9779487335464108 1.0 1.0 13 P63000,Q9UHB7,Q9Y4A5 3 +Abnormality of globe size 0.2233471495738345 0.0253330296820787 0.9797893285029105 1.0 1.0 67 Q96N67,Q9H2M9,Q9UHX1,Q3LXA3,Q15125,Q9Y5P6,P30533,O75431,O75569,O15111,P21964,O00192,Q08AM6,P19447,P53701,P41227,P18074,Q86XI2,Q01968 19 +Curly eyelashes 0.2482138888204862 0.0242138506662423 0.9806820301358974 1.0 1.0 6 Q9UQE7 1 +Gastrointestinal carcinoma 0.2285807420284803 0.0239247653515744 0.9809126200407404 1.0 1.0 35 Q09472,P52701,P28340,Q13043,Q13485,P62854,P61254,P62081,P63167,P62899,P62913 11 +Chromosome breakage 0.2529570437951269 0.022742139080755 0.9818559623921436 1.0 1.0 13 Q969G3,P54132,P35240 3 +Basal cell carcinoma 0.247230271961374 0.0219861789558433 0.9824589804697434 1.0 1.0 16 P18074,Q9H1A4,P02545,P19447 4 +Ulnar deviation of finger 0.2529681631746275 0.0208138361827013 0.983394160452678 1.0 1.0 9 Q9H2M9,Q9Y2D4,P11274,Q9Y3E5 4 +Short 1st metacarpal 0.2417779193055403 0.0207562294545245 0.9834401140442302 1.0 1.0 6 Q9UQE7 1 +Incomitant strabismus 0.2396954670300317 0.0205219437081365 0.9836270072138038 1.0 1.0 20 Q09472,O00429,O60313,Q7LGA3 4 +Prominent supraorbital ridges 0.2506838113917088 0.0191591294270534 0.9847141616052753 1.0 1.0 13 Q8IWS0 1 +Cleft upper lip 0.2271632701096453 0.0178471875748088 0.9857607605030748 1.0 1.0 35 O15111,O15344,P41227 3 +Long eyelashes 0.2238192502763701 0.0177890199295234 0.9858071642023598 1.0 1.0 43 Q96AX1,Q09472,Q9UHB7,Q9UQE7,Q96N67,Q9UM00,Q9UHX1,Q92974,Q8IYI6,Q969G3,P62266,Q4J6C6,P41227 13 +Impaired tactile sensation 0.235276532137529 0.0177110301996024 0.9858693812018278 1.0 1.0 6 O15269,O15270,P55072,P19367,Q9Y6X9 5 +Relative macrocephaly 0.2264456811110166 0.017695797352856 0.9858815333506068 1.0 1.0 37 Q15392 1 +Allergy 0.2346347045736227 0.0174333872053501 0.9860908740604442 1.0 1.0 6 P42345,Q01082 2 +Upper limb amyotrophy 0.2455605095368614 0.0161495082424587 0.9871151167883504 1.0 1.0 15 P31483 1 +Muscle fibrillation 0.2455035971223046 0.0160467137869372 0.9871971242705366 1.0 1.0 15 P22314,Q13510,P41250,P51114,Q9BTW9,Q9NQT5,Q9NX46,Q16637,Q9H0U9,P55072,O00567,P50570,O95831,P04792 14 +Aplasia hypoplasia of the capital femoral epiphysis 0.2395240945984349 0.0159212763013532 0.9872971961191648 1.0 1.0 7 O60568 1 +Oromotor apraxia 0.2101016138672994 0.0158626801817003 0.9873439431548812 1.0 1.0 5 Q9BVA1,P42356,Q14683,Q8N3U4 4 +Abnormal head movements 0.2466255410400575 0.0150172264426822 0.9880184372181912 1.0 1.0 9 P20700,Q01082,P41227 3 +Abnormality of the tonsils 0.2420213599115804 0.0146825998623972 0.9882854011619328 1.0 1.0 8 P21964,P54132 2 +Duplication of thumb phalanx 0.2356765736025813 0.0143163223154314 0.9885776176414038 1.0 1.0 23 P62081,P62899,P41227,P34897 4 +Abnormality of male internal genitalia 0.2448038823450108 0.0137096610486299 0.9890616157701788 1.0 1.0 14 Q09472,Q8IWS0 2 +Dyskinesia 0.2219595952425467 0.0123098996151586 0.9901783692038836 1.0 1.0 72 Q9P0J0,P15311,Q9UBX3,P04062,Q96N66,Q9NUQ7 6 +Dilated fourth ventricle 0.2224857804325998 0.0112701380721121 0.99100792119088 1.0 1.0 43 P23786,O14802,Q15125,Q9Y5P6,P49959,Q969G3,O60826,Q9Y487,P63000,Q10713 10 +Hand tremor 0.2452095808383233 0.0098566087034965 0.992135691433659 1.0 1.0 11 Q9UNE7,O94905,Q96KR1,Q9ULM3,Q9H2M9,Q16637,O00567,P56192,Q15120,O95140 10 +Abnormality of the nasal alae 0.2078862339105579 0.008593720653066 0.9931432873681996 1.0 1.0 180 Q9UQE7,Q96N67,O60568,Q9H2M9,Q9UHX1,Q96C36,P04062,O75381,P40855,Q13409,O75431,Q9Y487,Q9Y4A5,Q15392,P50542,P16435,Q9H6U8,Q9Y3B2,Q9Y5P4,Q10713,O75695,Q2TAL8,P35573,P36507,Q08AM6,Q969G3,Q9UHB7,Q9NS87,P41227,P18074,Q7LGA3,O15344,Q9NVI7,P51608,P63000,Q8WXI9 36 +Tetraparesis 0.2231396856846365 0.0081262270457915 0.9935162802620132 1.0 1.0 39 P07602,Q9HA77,Q9UBX3 3 +Renovascular hypertension 0.230930302123838 0.0077385686348461 0.9938255771899468 1.0 1.0 8 Q9Y4P3,P35250,Q9UIG0,Q08AM6,P21359,P42224,Q15056 7 +Pneumonia 0.2181734616183419 0.0073439688059767 0.9941404133464458 1.0 1.0 55 Q09472,P06753,P20700,Q96EY7,P04062,P63000,Q9UHB7 7 +Plagiocephaly 0.2236936380827205 0.0058378181292036 0.9953421215027918 1.0 1.0 37 Q9UQE7,Q15233,Q96A33,Q10713,P63000,Q9UHB7 6 +Impaired pain sensation 0.2356858254154266 0.0056106999116162 0.9955233326527824 1.0 1.0 18 O15269,P55072,P04792,O95140,Q13045,P51608,P61978 7 +Neurogenic bladder 0.2264433143882708 0.0053730610229926 0.995712938193271 1.0 1.0 8 Q9BTW9,P83436,Q9Y3I1,O43318,Q04446,P50336,O76024 7 +Abnormal circulating iga level 0.2404746675843355 0.004665059646687 0.9962778344334682 1.0 1.0 13 P13051,P54132 2 +Limb muscle weakness 0.2213265670968213 0.004583931595763 0.996342564560569 1.0 1.0 83 O15269,P35240,Q9Y5P6,P50570,P46976,Q8WXH0,O60318,O95140,Q13126,P54886,P41250,P36551,P06753,P08397,Q15650,Q96RR1,Q969G3,Q96BR5,Q86U42,P53007,P12235,P02545,P31483,O43819 24 +Deep philtrum 0.2328492629323255 0.0035057266532909 0.9972028405585158 1.0 1.0 21 Q96S52,Q09472,Q01968,P41227 4 +Leukoencephalopathy 0.2254528811171252 0.0019910232084045 0.9984113943713986 1.0 1.0 93 P18074,Q9Y285,Q9Y263,O43681,O75380,P07602,Q9UHX1,O60313,O43676,O00429,Q13144,Q86Y39,Q96TA2,P27635,P63000,Q01968,O75306 17 +Oligodactyly 0.2003683608210561 0.0015101295644638 0.9987950913936664 1.0 1.0 7 Q9UQE7 1 +Absent epiphyses 0.2170987583363123 0.0011789719898266 0.9990593166696192 1.0 1.0 8 O60568 1 +Anteriorly placed anus 0.2362043430106241 0.000983059166515 0.999215632395018 1.0 1.0 11 P53701,P48651 2 +Death in childhood 0.2286484978057034 0.0007801197909192 0.999377554526384 1.0 1.0 25 Q96AX1,P18074,P50542,P51159,Q6NUQ1,Q6P3W7,O75431 7 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1d17bf40947fc537d0acba73c70ba6da90c8cd4b --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood folate concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal germ cell morphology", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm head morphology", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary molar morphology", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acephalic spermatozoa", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous fistula", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral arteriovenous malformation", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical c2 c3 vertebral fusion", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal stromal edema", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Discoid lupus rash", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal clonic seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal hemiclonic seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the bladder", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lupus anticoagulant", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesomelia", "Metabolic acidosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microangiopathic hemolytic anemia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary cystadenoma of the epididymis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral arteriovenous fistula", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior helix pit", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postprandial hyperglycemia", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal polyposis", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced number of corneal endothelial cells", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary cusp", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal ectropion", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "ALG9", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARSA", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "BANF1", "BAZ1B", "BCAP31", "BCAT2", "BCKDHB", "BCL10", "BCR", "BCS1L", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CAPN5", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBFB", "CBL", "CC2D1A", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CD320", "CD3EAP", "CDC40", "CDC42", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CELF2", "CENPF", "CEP112", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHEK2", "CHM", "CHMP1A", "CHORDC1", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA7", "COASY", "COG2", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTNA", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S3", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EP300", "EPB41", "EPRS", "EPS8", "ERAL1", "ERCC2", "ERCC3", "ERCC4", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAH", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIBP", "FIP1L1", "FKBP10", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC6", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKB", "IMPA1", "IMPDH1", "INF2", "INPP5K", "INPPL1", "INTS1", "INTS8", "IRAK1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITPA", "IVD", "JUP", "KARS", "KAT5", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5C", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMC1", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LSS", "LUZP1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MESD", "MFN2", "MGAT2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MLH1", "MMAB", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NACC1", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEK9", "NELFA", "NEMF", "NF1", "NF2", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OTUD5", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PAPSS2", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP1R21", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB18", "RAB27A", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RRP7A", "SAMHD1", "SARS", "SARS2", "SASS6", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHAF2", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHPK", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC39A14", "SLC5A6", "SLC9A3R1", "SLTM", "SMAD4", "SMARCA4", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNRNP200", "SNRPE", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQOR", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF6", "TALDO1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBK1", "TBL2", "TCF20", "TCOF1", "TDP2", "TDRD7", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM50", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TNRC6B", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBA5", "UBE3A", "UBE4A", "UBR7", "UBTF", "UFC1", "UFD1", "UFM1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAC14", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP11", "WDR1", "WDR11", "WDR26", "WDR36", "WDR4", "WDR45", "WDR73", "WFS1", "WIPI2", "WNK1", "WRAP53", "XIAP", "XPC", "XPNPEP3", "XRCC1", "XRCC4", "YARS", "YARS2", "YEATS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "YY1", "ZC3H14", "ZCCHC8", "ZEB1", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ACADVL", "ACSF3", "ACTN1", "ACTN4", "ADD3", "ADK", "ADPRHL2", "AFF4", "AGL", "AIFM1", "AIMP1", "AIP", "AKAP9", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALG11", "ALG9", "ANAPC1", "ANKFY1", "ANKLE2", "ANO6", "APC", "APRT", "ARCN1", "ARHGEF2", "ARID1A", "ARID2", "ARVCF", "ASAH1", "ASNA1", "ATAD3A", "ATP11C", "ATP2A2", "ATP5A1", "ATP6V0A2", "ATXN10", "B3GALT6", "BAZ1B", "BCAP31", "BCL10", "BCR", "BLM", "BLVRA", "BRAT1", "BRD4", "C21orf59", "CALD1", "CAMK2G", "CAPN5", "CARS", "CARS2", "CASP8", "CC2D1A", "CCDC22", "CCDC47", "CDC6", "CDK6", "CEP112", "CHD1", "CHD3", "CHUK", "CLIP1", "CLPB", "CLPX", "CNNM4", "COA7", "COG7", "COL4A3BP", "COMT", "COX2", "COX6B1", "CPOX", "CPT2", "CREBBP", "CRTAP", "CSNK2B", "CTBP1", "CTDP1", "CTNNA1", "CTNNB1", "CTU2", "CWF19L1", "CYFIP2", "DARS2", "DAXX", "DCTN1", "DCTN4", "DDRGK1", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX37", "DHX38", "DIABLO", "DICER1", "DLD", "DLG1", "DNA2", "DNAAF5", "DNAJB11", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPYSL5", "DST", "DTNA", "DYNC1I2", "DYNLL1", "EBP", "ECE1", "EHHADH", "EIF2B1", "EIF2B3", "EIF2B5", "EIF4H", "ELP1", "EMC1", "EMD", "EP300", "ERCC2", "ERCC3", "ERCC4", "ERLIN2", "EWSR1", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXTL3", "EZR", "FAR1", "FARSA", "FASN", "FBXO7", "FDFT1", "FECH", "FHL1", "FKBP10", "FLAD1", "FLII", "FXR1", "GALM", "GALNT2", "GARS", "GATAD2B", "GATB", "GBA", "GBE1", "GCLC", "GDAP2", "GFM1", "GFPT1", "GGCX", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GPI", "GSR", "GTPBP3", "GYG1", "HADHA", "HADHB", "HCCS", "HDAC6", "HERC2", "HK1", "HMBS", "HMGA1", "HMMR", "HMOX1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HS2ST1", "HSD17B4", "HSPB1", "IARS", "IDH3A", "IDH3B", "IFT27", "KARS", "KAT5", "KDSR", "KIF15", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIFBP", "KLC2", "LAMC1", "LARP7", "LARS2", "LBR", "LEMD2", "LETM1", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "MAGT1", "MAP2K1", "MAP2K2", "MAP3K7", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCM10", "MCM3AP", "MCM4", "MCM5", "MCM6", "MECP2", "MED12", "MFN2", "MGAT2", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MORC2", "MPG", "MRE11", "MRPS16", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTOR", "MTX2", "MYH9", "MYO5A", "NAA10", "NAA15", "NAGLU", "NANS", "NCAPD3", "NCAPG2", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS6", "NEDD4L", "NF1", "NF2", "NNT", "NONO", "NOP56", "NSD2", "NSMCE3", "NUBPL", "NUP107", "NUP188", "NUP93", "OCRL", "OGDH", "OPA1", "OTULIN", "P3H1", "P4HA2", "PABPN1", "PDK3", "PEX1", "PEX14", "PEX19", "PEX5", "PFKM", "PGM3", "PHF6", "PI4KA", "PIGK", "PIGS", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR3A", "PON2", "POR", "PPOX", "PPP1R21", "PPP2R1B", "PPP2R5D", "PPT1", "PREPL", "PRKAR1A", "PRKCA", "PRKCSH", "PRKRA", "PRPF3", "PRPF31", "PSAP", "PTCD3", "PTDSS1", "PTRH2", "PUF60", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "QARS", "QRICH1", "RAB27A", "RAB3GAP2", "RAC1", "RAI1", "RARS", "RARS2", "RBMX", "RDX", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNF2", "RP2", "RPL10", "RPL11", "RPL21", "RPL26", "RPL31", "RPS23", "RPS26", "RPS7", "RPSA", "RREB1", "SAMHD1", "SARS", "SASS6", "SCARB2", "SCO1", "SCO2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24D", "SFXN4", "SGPL1", "SHMT2", "SIN3A", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A13", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A4", "SLTM", "SMAD4", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMN1*", "SMS", "SPECC1L", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQOR", "SQSTM1", "SSBP1", "SSR4", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STUB1", "SYNE2", "TARS2", "TBCD", "TBK1", "TBL2", "TELO2", "TFAM", "THOC6", "TIA1", "TKFC", "TMCO1", "TMEM126A", "TMEM199", "TMTC3", "TNPO3", "TOE1", "TOR1AIP1", "TPM3", "TPP1", "TRAPPC11", "TRIP4", "TRMU", "TRRAP", "TSC2", "TSPYL1", "TTC19", "TUBB2B", "TUBB4A", "TUBG1", "TUBGCP2", "TWNK", "UBA1", "UBA5", "UFC1", "UFM1", "UFSP2", "UGP2", "UNG", "UPF3B", "UQCRC2", "USP8", "VAC14", "VAMP7", "VCP", "VIM", "VPS33A", "VPS33B", "VRK1", "WARS", "WDR73", "WFS1", "XIAP", "XPNPEP3", "XRCC1", "YEATS2", "YME1L1", "YY1", "ZEB1", "ZFR", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1721854dfe623935cbec75f6021a26a1318dfee1 --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Huntingtons disease", "1": "Cardiac muscle contraction", "2": "Vasopressin regulated water reabsorption", "3": "Oxidative phosphorylation"} \ No newline at end of file diff --git a/msigdb_kegg/advanced/plot_0.png b/msigdb_kegg/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..80843aa7059e8e1641fc0ea9fe9775e0ca713750 --- /dev/null +++ b/msigdb_kegg/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c5edb37f65fb0b1a0936bde564a479c69011de119def468477ff1664002260c +size 221313 diff --git a/msigdb_kegg/advanced/plot_1.png b/msigdb_kegg/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..07ad1120a8a560398ea008f4480fa026e5a012a1 --- /dev/null +++ b/msigdb_kegg/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ad9c26b2ab432691bcd52b7211ab6d361a1fe2671bc52a04482a3d2b852bab8b +size 207403 diff --git a/msigdb_kegg/advanced/plot_2.png b/msigdb_kegg/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d173de8fb40218a183c161fbfcae8bb13ea5fc38 --- /dev/null +++ b/msigdb_kegg/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12569c699066dabdf716a9a775d8f13c116b887dff91801a1498bf0a59b9877c +size 200114 diff --git a/msigdb_kegg/advanced/plot_3.png b/msigdb_kegg/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..ff5321c09654af61110598ce38054259afa97c8d --- /dev/null +++ b/msigdb_kegg/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be095410e2518d2a53f80ec67243c01582c249309b980e1b6f619c90d9cfa3bc +size 214740 diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4a2d8bcf16cfc750abd5ca146b8da4bb77c51c07 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Huntingtons disease", "1": "Cardiac muscle contraction", "2": "Vasopressin regulated water reabsorption", "3": "Oxidative phosphorylation", "4": "Steroid biosynthesis", "5": "Parkinsons disease", "6": "Non small cell lung cancer", "7": "Base excision repair", "8": "Adherens junction", "9": "Dna replication", "10": "Progesterone mediated oocyte maturation", "11": "Homologous recombination", "12": "Cell cycle", "13": "Regulation of actin cytoskeleton", "14": "Glioma", "15": "Epithelial cell signaling in helicobacter pylori infection", "16": "Erbb signaling pathway", "17": "Renal cell carcinoma", "18": "Leukocyte transendothelial migration", "19": "Oocyte meiosis", "20": "T cell receptor signaling pathway", "21": "Pathways in cancer", "22": "Prostate cancer", "23": "Protein export", "24": "Vascular smooth muscle contraction", "25": "Alzheimers disease", "26": "Natural killer cell mediated cytotoxicity", "27": "Aminoacyl trna biosynthesis", "28": "Nucleotide excision repair", "29": "Ribosome", "30": "Mapk signaling pathway", "31": "Chemokine signaling pathway", "32": "Gnrh signaling pathway", "33": "Long term potentiation", "34": "Insulin signaling pathway", "35": "Colorectal cancer", "36": "Jak stat signaling pathway", "37": "Endometrial cancer", "38": "Proteasome", "39": "Wnt signaling pathway"} \ No newline at end of file diff --git a/msigdb_kegg/basic/plot_0.png b/msigdb_kegg/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f2fa2fdd93e36b42379460404e52711a0a96e820 --- /dev/null +++ b/msigdb_kegg/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e2d332ce3bef7315c8f507ea5acda4f5acf1097e6fa71d536804f5baf966c86 +size 143263 diff --git a/msigdb_kegg/basic/plot_1.png b/msigdb_kegg/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6d5b1f790340935b27fa691fef3740988f6b31db --- /dev/null +++ b/msigdb_kegg/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0cf68e5ad2ed532d342caea649d3e769fb91a6e8caadc20e19d12939ed0566f +size 142539 diff --git a/msigdb_kegg/basic/plot_10.png b/msigdb_kegg/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..c801899c45d5deb93059b4871f50ff1e12d6855c --- /dev/null +++ b/msigdb_kegg/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb036208ce3645dd7e8c9c0954d3011f8999dd4fb38bc5d9435b1dd3b8ef3105 +size 152973 diff --git a/msigdb_kegg/basic/plot_11.png b/msigdb_kegg/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..d557216c07526416de436ae1f17144c64af02490 --- /dev/null +++ b/msigdb_kegg/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd7b154a4182063862629719371a3789661ae53e4c0ac0984a00951df8d7f22b +size 138116 diff --git a/msigdb_kegg/basic/plot_12.png b/msigdb_kegg/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..058ca2971a9989b41cdae762a63d3114572e01c0 --- /dev/null +++ b/msigdb_kegg/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f69425fa9224bf6721f64104803eb47674d2e60139c1b48099fd13b55079343 +size 140930 diff --git a/msigdb_kegg/basic/plot_13.png b/msigdb_kegg/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..8622cd8e9b28b717ac43ec2c8992f2d8672210ae --- /dev/null +++ b/msigdb_kegg/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e442032a1974f718c2b5d9b6674bc9ef2a21d73c0613f3e741e728c3fa83707 +size 147551 diff --git a/msigdb_kegg/basic/plot_14.png b/msigdb_kegg/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..0d2ddab7facbadf5b79ffaa23d4cf366a23e34c5 --- /dev/null +++ b/msigdb_kegg/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e98410f2c5527b6c508cc3fd47e611839f6eb6c5ea11568c65ae2f506a3f343 +size 137071 diff --git a/msigdb_kegg/basic/plot_15.png b/msigdb_kegg/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..43ef35b59751f45915d85fc7aa09a624ddf70add --- /dev/null +++ b/msigdb_kegg/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6291cd8c3ac04ead07ae3245772172b220242e6a04827845bd4da8418c44858 +size 148167 diff --git a/msigdb_kegg/basic/plot_16.png b/msigdb_kegg/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..8d774660adad947cde7985cfbc9360e629c49652 --- /dev/null +++ b/msigdb_kegg/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf92a7957772b38f7dbdeb7a4e27ccbf4e656882a6503a19740a6ebe27eb8650 +size 137183 diff --git a/msigdb_kegg/basic/plot_17.png b/msigdb_kegg/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..cfa1a7c9e9e82ef3c462335b44e77eb97586641a --- /dev/null +++ b/msigdb_kegg/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51b7bee25d4a4aec9b649e3d371c96a30b9c83fdfd68f2ea833d1952ee3197e6 +size 143611 diff --git a/msigdb_kegg/basic/plot_18.png b/msigdb_kegg/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..6e9d4f7af6533d2cfabf94671eb730ce0b35f01a --- /dev/null +++ b/msigdb_kegg/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6acb2809241c7bdbd75359761bb92dd84e0374c8826bb732ba4c757c7e31dc57 +size 151262 diff --git a/msigdb_kegg/basic/plot_19.png b/msigdb_kegg/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..59be72ecb7048365920dc46c1ff594d6fbc53278 --- /dev/null +++ b/msigdb_kegg/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:233e3d4c730e234c88066c7630b5b0049bfe97d70dbca2a70a6099132d8eec4e +size 148156 diff --git a/msigdb_kegg/basic/plot_2.png b/msigdb_kegg/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e71996ae63988b1e3d3617e108edc41e50df0fef --- /dev/null +++ b/msigdb_kegg/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68f62ea4444f9dbfcc5096c1552e94a7f21a0f684fa1757939b2a6a120a1e5b8 +size 143728 diff --git a/msigdb_kegg/basic/plot_20.png b/msigdb_kegg/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..e99968a46b7068d63a4af4b1749d058cd78a3095 --- /dev/null +++ b/msigdb_kegg/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:324f9f533efc353ac5dce5a6bd6ddd98c807327e22665fb8b966220a82fa0eb8 +size 140519 diff --git a/msigdb_kegg/basic/plot_21.png b/msigdb_kegg/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..3a2ba5bd429ed83b567b611343a3b2bc8c96558e --- /dev/null +++ b/msigdb_kegg/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14b5c6f1a7af1304865077f0e9f4ef02d1341f13dcccccd9642fd1d523503906 +size 149688 diff --git a/msigdb_kegg/basic/plot_22.png b/msigdb_kegg/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..d59573251e250b150fb13f29f9c55d51fd0bad96 --- /dev/null +++ b/msigdb_kegg/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:869dc0d20a62cdef03744204f4945cd3de60650b7603d62377d60f267f532ec9 +size 145565 diff --git a/msigdb_kegg/basic/plot_23.png b/msigdb_kegg/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..93eaf6a3e486b4739a269ecfa64691167e64f20f --- /dev/null +++ b/msigdb_kegg/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e25606f1115327e14c036985d4258c3f8b03a3f897b1e5c230c7b733f8b9451 +size 121564 diff --git a/msigdb_kegg/basic/plot_24.png b/msigdb_kegg/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..1f6cbec7cf79b0f3c28f15f4af10951f34e88432 --- /dev/null +++ b/msigdb_kegg/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:57b7a3e913278505c7c6f22a5c894583be30acdda4ee74ea7254e996ee5e225f +size 154330 diff --git a/msigdb_kegg/basic/plot_25.png b/msigdb_kegg/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..c20b8031aa8cbd01be40a37745c7c412b5eaf30b --- /dev/null +++ b/msigdb_kegg/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:644070606d6df4abae8592dd54f19783ac2bce5e1d93945479bf146b90ead63d +size 147593 diff --git a/msigdb_kegg/basic/plot_26.png b/msigdb_kegg/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..29597bf12cdb202b466eaad61a21f0e4c5a947c8 --- /dev/null +++ b/msigdb_kegg/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:18f0e754096062d86ee6892054a287e55094526cd17c4bfaa2b4d502917202e8 +size 145319 diff --git a/msigdb_kegg/basic/plot_27.png b/msigdb_kegg/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..2d1c23abec7f3d15402c74babc8ab03cad4c10fe --- /dev/null +++ b/msigdb_kegg/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff95c29d432151de6f4be995016276d7e8e83ab94c524640a13269573780c034 +size 152465 diff --git a/msigdb_kegg/basic/plot_28.png b/msigdb_kegg/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..47acca55936192ffc73e8928c9c6245d5696afb5 --- /dev/null +++ b/msigdb_kegg/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a996201e603337ad7079c59ed47d30ee7b8683a0a364fae12bc979a9ab0126a +size 153906 diff --git a/msigdb_kegg/basic/plot_29.png b/msigdb_kegg/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..f659cb16e9614260b3577642162f81d5348998f8 --- /dev/null +++ b/msigdb_kegg/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bd33349918c9f946472bb22d108655d56cbb241a7d3e6bfd397d07e96dc55e7 +size 147072 diff --git a/msigdb_kegg/basic/plot_3.png b/msigdb_kegg/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..454630f68eb8b4ef32cc153cf08ef85bf4e07949 --- /dev/null +++ b/msigdb_kegg/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:969e2bbf49cc70cfc97f2f12da7e420ea5e8c7d31e62cf8cc4272765bff05e91 +size 142011 diff --git a/msigdb_kegg/basic/plot_30.png b/msigdb_kegg/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..f428889f29e8e553690be76a479994f09b70c013 --- /dev/null +++ b/msigdb_kegg/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b69857d84d377a79830420b7033a9b924b12f2afa3e8c0daafc6391733614d71 +size 139587 diff --git a/msigdb_kegg/basic/plot_31.png b/msigdb_kegg/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..b237268b6c7ee80c125433c5e2b545a43990f55f --- /dev/null +++ b/msigdb_kegg/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9bfd61036b8eac9211871dacf07eb8a82ed07cbd0acdf32a0adc655161431a8 +size 154902 diff --git a/msigdb_kegg/basic/plot_32.png b/msigdb_kegg/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..c2e8269f158648b24569cdad4908be2e64a7290e --- /dev/null +++ b/msigdb_kegg/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:310dbcc734a7fc438305c33acf091e031905bc7dec6e9874797ffca9a16f6c44 +size 152578 diff --git a/msigdb_kegg/basic/plot_33.png b/msigdb_kegg/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..47db93425ef581f8140cde69bc323c163581e93c --- /dev/null +++ b/msigdb_kegg/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:621694c978a46fe3aca361470f22e408c32d92347e0ab0e6255b100d5d754218 +size 142617 diff --git a/msigdb_kegg/basic/plot_34.png b/msigdb_kegg/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..fa79984250962b31ff608883632dd81e5baf1394 --- /dev/null +++ b/msigdb_kegg/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e280e867198e9e1d3a554742546e3852635b44e0b0f2462d6aca09ab1a900bbe +size 153132 diff --git a/msigdb_kegg/basic/plot_35.png b/msigdb_kegg/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..0234188845e63b476971bf4e5e2a006eedf0aab8 --- /dev/null +++ b/msigdb_kegg/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:439cc96638c535d9c5730a520fc505be67532caf39a67e673bdbee7d48995d52 +size 147131 diff --git a/msigdb_kegg/basic/plot_36.png b/msigdb_kegg/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..0493d37954e18c98acc4832771597911d78ff5fb --- /dev/null +++ b/msigdb_kegg/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2466f2218f1ba086e3002a0d7af0edc4aef4f6544f9232c420b6def3a764843 +size 150415 diff --git a/msigdb_kegg/basic/plot_37.png b/msigdb_kegg/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..166dfe4d13d3076decdc95744212150d6146edf4 --- /dev/null +++ b/msigdb_kegg/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2174151f31a70eab7de0f41109579d2e4e14a6fa953487796839e647685db55d +size 144452 diff --git a/msigdb_kegg/basic/plot_38.png b/msigdb_kegg/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..f27ee73da227906daf3f4054b3df09dd8cea2bc0 --- /dev/null +++ b/msigdb_kegg/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a44b294ae3e5a3f74751e5344707b64bf5ac0ceb0585cd6894e6a5124e0b1b91 +size 149860 diff --git a/msigdb_kegg/basic/plot_39.png b/msigdb_kegg/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..a60f0d5ea46304af7665f3ac9e0d14ec22d94507 --- /dev/null +++ b/msigdb_kegg/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2fc2d75d508830215bcac1dbae77713edea6fc2496131480c27efd7f4bb7c5cc +size 154730 diff --git a/msigdb_kegg/basic/plot_4.png b/msigdb_kegg/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..34368275d872fde78d2196d2f4e8e33fb8aa240e --- /dev/null +++ b/msigdb_kegg/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de51c9fd211ab48e2ad19d26ce97783c43b033a7ff00701368b747926809588d +size 134345 diff --git a/msigdb_kegg/basic/plot_5.png b/msigdb_kegg/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..8c278170334fc3af56c82a8d35022e2a5809b929 --- /dev/null +++ b/msigdb_kegg/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:620e14459e16e020c73dd9d22ec6a93aa6ac73ba36cd9678fa84a87ac75374b6 +size 143192 diff --git a/msigdb_kegg/basic/plot_6.png b/msigdb_kegg/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..88cf151e7aec71c11a3d66ebd41aa3d3f15c563b --- /dev/null +++ b/msigdb_kegg/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:afb0cea9daf07ea506edcc9f5f065169d1f6330e890f2d85fd99531db94d945c +size 134907 diff --git a/msigdb_kegg/basic/plot_7.png b/msigdb_kegg/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..67e31472e428fc489edd9b94be9e8dec91ea7037 --- /dev/null +++ b/msigdb_kegg/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8440cd9afd50b63bdbb19ba1e13e387c2046e42166180a4de58b1c60ccb7c762 +size 133574 diff --git a/msigdb_kegg/basic/plot_8.png b/msigdb_kegg/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..11385e8d2c7c6d8f5d1364fe3ad916484dd6e48e --- /dev/null +++ b/msigdb_kegg/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2e07f55d58a9e09de166dddebd2497b27dbf9ad6be9b7bd4d7bfd83b5fbca10 +size 139399 diff --git a/msigdb_kegg/basic/plot_9.png b/msigdb_kegg/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..eec1368c268c1f2a4f5383aaadb439cb9dede11d --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:398bf754dc6b5c51aad12e5b8266758701fda707d678982fbcc56073ae34425a +size 139740 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ff4b06d0cc4918d69839707d78a7afbf425b92bc --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd1de22c65e64c186f43843c98c0d1bebd184dca7883b5473e35966c15ec369a +size 86471 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a2186e61b7bc2f291578bd569e5a626aabec46ab --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Huntingtons disease 13 82 2.635036449001109 0.0084128248683847 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 0.0047982572492556 0.000529591303577 0.0002634217628024 0.0009234153495659 +Cardiac muscle contraction 5 21 2.62727180964451 0.0086072549828457 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.1880892294635792 0.0681167311872175 0.0007016746800212 0.0210947346086547 +Vasopressin regulated water reabsorption 5 18 2.451056522049508 0.0142437584778118 4.936893203883495 16.320388349514563 -0.0354172931004201 0.6873434085893579 3.04511355476444 1.4957129172197627 0.6574245748590921 0.275046760971588 0.1495431827221669 0.043496878178469 0.0520565373494006 0.0063226090272968 +Porphyrin and chlorophyll metabolism 3 14 2.3859278681588245 0.0170360921351764 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.0037480987371249 3.318189305409523e-05 0.0011993766429203 0.0002808101441202 +Oxidative phosphorylation 16 59 2.0296028939217066 0.0423969205186758 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 0.0117679192899753 0.0166249475514907 0.0008595449943348 0.0001306204535395 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1a6ef08cb995ee7e6ad36a555397f62961d50916 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 17.69060773480663 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..19ff98207c4ab31c784731cc784bb44fd03a6861 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..373a691a5ba6352ebeb149dbd7693a73c590ff31 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,81 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.8208420424007159 2.644045935484139 0.0081921537742817 0.7743763174363134 0.096966070830131 2 Q92643 1 +Huntingtons disease 0.4307713253279182 2.635036449001109 0.0084128248683847 0.7832829399686269 0.096966070830131 82 Q9UJW0,P45880,P18859,Q00059,P51970,P14854,P12235,O43676,P22695,Q9UDW1,P21796,P27695,Q13561 13 +Cardiac muscle contraction 0.6623711449353105 2.62727180964451 0.0086072549828457 0.790840163722842 0.096966070830131 21 P06753,P14854,Q9UDW1,P22695,P67936 5 +Vasopressin regulated water reabsorption 0.6686489013595918 2.451056522049508 0.0142437584778118 0.9254777532115824 0.1356905412886291 18 Q9UJW0,Q96FJ2,Q13409,P17252,Q13561 5 +Porphyrin and chlorophyll metabolism 0.7188434518040511 2.3859278681588245 0.0170360921351764 0.9554035278872194 0.1541766338233466 14 P53004,P09601,P30519 3 +Steroid hormone biosynthesis 0.8214013686256395 2.2823664811604685 0.0224677125402661 0.9836419675412524 0.184847998626735 3 Q53GQ0 1 +Oxidative phosphorylation 0.40970953933366 2.0296028939217066 0.0423969205186758 0.9996068288374826 0.2475433101251717 59 P18859,O43678,P51970,O75380,P06576,Q9Y5K8,Q93050,P14854,O43676,Q9UDW1,O75964,P22695,P56134,Q86Y39,Q9Y487,O75306 16 +Nicotinate and nicotinamide metabolism 0.7794413919248192 1.904488609647704 0.056846578717896 0.9999749155633796 0.3032670605432672 6 P43490 1 +Steroid biosynthesis 0.6979201197066904 1.884173360628501 0.0595415296703827 0.9999850558355092 0.3032670605432672 10 P37268,Q15125,Q16850,Q15800,Q15392 5 +Calcium signaling pathway 0.5435474233049195 1.7666236625432343 0.0772912754521606 0.9999995249957506 0.3587107912010532 19 P45880,P21796,P12235,P16615 4 +Aldosterone regulated sodium reabsorption 0.7012214523156641 1.7420840811200704 0.0814937326734472 0.9999997920952336 0.3687591403473489 8 P17252,Q96PU5 2 +P53 signaling pathway 0.5934164219722626 1.6908738385499011 0.0908609008540772 0.9999999674844746 0.3915672155854283 14 Q00534,P24941,O95067 3 +Parkinsons disease 0.3835621544793253 1.6785530200756094 0.09323918907844 0.9999999797611264 0.3924719354232013 55 P18859,P45880,O43678,P51970,O75380,P06576,P14854,P12235,O43676,Q9UDW1,P22695,P21796,O75306 13 +Non small cell lung cancer 0.6010379766652728 1.6406185388010894 0.1008766242220038 0.9999999956218436 0.4057481996485043 13 Q00534,Q13043,P36507,P27361,P17252 5 +Base excision repair 0.5398114314355108 1.5835442445073276 0.1132974705395355 0.9999999996469724 0.4135720658677428 17 Q9UGN5,P28340,P13051,P09429,P18887,P39748,P18858,Q9NR33,P09874,Q07864,P27695,P29372,Q9Y2S7 13 +Alpha linolenic acid metabolism 0.6675627240143274 1.5808836209199295 0.1139046500201206 0.9999999996881378 0.4135720658677428 3 O95864,O15254 2 +Vibrio cholerae infection 0.5045337434681424 1.5517686089498326 0.1207175995557388 0.9999999999228676 0.420190106145937 20 P24390,Q9Y487,Q93050 3 +Abc transporters 0.7193660308709661 1.5320796647611796 0.1255027771763406 0.999999999971274 0.4246244401586356 4 P08183,P28288 2 +Prion diseases 0.6502218221282197 1.4984502652211389 0.1340163051727778 0.9999999999951106 0.4410354770231416 8 P36507,P17252,P31948 3 +Adherens junction 0.4373606656936366 1.4479881807637665 0.1476203561113847 0.9999999999997216 0.4639038589972357 28 Q09472,P35221,O94887,P67870,Q13485,O43707,P27361,Q9UQB8,P63000,Q9NWH9,P12814 11 +Apoptosis 0.4620849734142876 1.444301175567454 0.1486542752587827 0.9999999999997764 0.4639038589972357 24 Q9Y2C4 1 +Dna replication 0.4194364745129529 1.4134579399203224 0.1575211199044177 0.9999999999999664 0.4751887117116602 31 P28340,P15927,P33992,P35244,Q9NR33,Q04837,P51530,Q14566,Q9Y2S7,P25205 10 +Hypertrophic cardiomyopathy hcm 0.6090687476924544 1.3649067157340782 0.1722823712329084 0.9999999999999988 0.497248717417573 9 P06753,P54619,P67936,P16615 4 +Proximal tubule bicarbonate reclamation 0.6188654141530676 1.347244349865841 0.1779015486175992 0.9999999999999996 0.5031278171841478 8 Q9UBX3 1 +Progesterone mediated oocyte maturation 0.4229277852769335 1.332165820358841 0.1828057053795282 1.0 0.5090435795953017 28 Q9UJX5,P24941,Q9UJX4,O95067,Q9H1A4,P17252,Q9UJX2 7 +Homologous recombination 0.5369040909173811 1.2813431335959031 0.2000731686899453 1.0 0.5486855080739409 13 P28340,P15927,P54132,P35244,Q04837 5 +Cell cycle 0.3450662998959311 1.2715070619950486 0.203548316705977 1.0 0.5498842585639082 57 Q09472,Q9UQE7,Q9UJX5,Q00534,P24941,Q13485,Q9UJX4,P33992,O95067,O14757,Q14674,P33991,Q9H1A4,Q14566,Q9UJX2,Q9UBD5,P25205 17 +Dilated cardiomyopathy 0.5864720541297712 1.2525023676725082 0.2103868661127235 1.0 0.5600003348000435 9 P06753,P16615,P67936 3 +Regulation of actin cytoskeleton 0.3498561930500239 1.2420710890156472 0.2142103343688657 1.0 0.5615474004145798 52 P35580,Q9Y2A7,Q9UQB8,Q16512,P12814,Q14185,Q13177,P15311,Q96F07,Q92888,Q13576,Q13464,P36507,P48426,P35241,P27361,P62136,P59998,P26038,P63000 20 +Melanoma 0.561971525170549 1.194441291248304 0.2323053929953631 1.0 0.5782997968508135 10 P36507,Q9NWH9,Q00534 3 +Glioma 0.4859444799341806 1.1828027219707322 0.236887341569183 1.0 0.5782997968508135 16 Q00534,P36507,P42345,Q13555,P27361,P17252 6 +Epithelial cell signaling in helicobacter pylori infection 0.4320331850409951 1.176314060308679 0.2394693992426071 1.0 0.5782997968508135 23 O15111,Q9Y5K8,Q93050,P63000,Q9Y487,Q9NWH9 6 +Erbb signaling pathway 0.4553863633389814 1.1173724902821858 0.2638350924259345 1.0 0.6027551502042087 18 Q13177,P36507,P42345,Q13555,P27361,Q16512,P17252 7 +One carbon pool by folate 0.5452863304754795 1.1090651253071948 0.2674020882870369 1.0 0.6027551502042087 10 P04818,P00374 2 +Thyroid cancer 0.5442279289863519 1.103658613267319 0.2697412550637619 1.0 0.6027551502042087 10 P36507,P27361,P12270,P06753 4 +Renal cell carcinoma 0.4324243044959872 1.0329743392192297 0.3016159074757762 1.0 0.6311971720782878 19 Q09472,P36507,P27361,Q16512,P63000,Q9NWH9 6 +Leukocyte transendothelial migration 0.3986486733529011 0.9766039032824416 0.3287652859630223 1.0 0.661183519547856 24 P35221,Q13464,P19174,Q13017,P15311,O43707,O75116,P17252,P26038,P63000,P12814 11 +Oocyte meiosis 0.3342179741219904 0.9095765038291274 0.3630458945706172 1.0 0.6973912136341817 43 Q9UQE7,Q9UJX5,P24941,Q9UJX4,O95067,Q13555,P27361,P62136,Q9H1A4,P17252,Q9UJX2 11 +Small cell lung cancer 0.4335271991388779 0.8646030005966601 0.3872567250407042 1.0 0.7301402836704943 16 O15111,Q00534 2 +Tyrosine metabolism 0.4930782997725882 0.7938656982332092 0.4272736206809804 1.0 0.7853969211920682 9 P21964,P14174,O60294 3 +Fc epsilon ri signaling pathway 0.4442820047311118 0.7660941695599124 0.4436202719438966 1.0 0.7950026655628246 13 P36507,P27361,P63000,P17252 4 +Notch signaling pathway 0.4508442946324987 0.7417195592974425 0.458257266678908 1.0 0.8052870414454597 12 Q8TDB6 1 +T cell receptor signaling pathway 0.3593747306533121 0.7300380464735572 0.4653669288344058 1.0 0.809917443452187 25 Q13177,P36507,O15111,P27361,Q16512,Q12959 6 +Chronic myeloid leukemia 0.3698034119726096 0.7020940417471011 0.482620517854182 1.0 0.8164942506015674 22 O15111,Q00534 2 +Pathways in cancer 0.2917033776492512 0.7012082730411043 0.4831730476272065 1.0 0.8164942506015674 66 Q09472,Q00534,Q13043,P36507,O15111,P24941,P06753,P63000,P17252,Q9NWH9 10 +Prostate cancer 0.3754473072949374 0.6863039029290027 0.4925214883107394 1.0 0.8164942506015674 20 Q09472,P24941,P36507,O15111,P42345 5 +Protein export 0.4099948062994815 0.6407633140682506 0.5216764714297719 1.0 0.8338426751165343 14 P67812,P09132,O76094,P49458,Q9Y5M8 5 +Acute myeloid leukemia 0.4296696450771695 0.6335061541427844 0.5264031633088084 1.0 0.8338426751165343 12 P36507,O15111,P42345 3 +Vegf signaling pathway 0.4027852427749627 0.6022076942009815 0.54703589468193 1.0 0.8477636165133683 14 P36507,P27361,P63000,P17252 4 +Vascular smooth muscle contraction 0.3686020481054704 0.5740931109965908 0.5659047948796325 1.0 0.8477636165133683 18 Q05682,Q13464,P36507,P27361,P62136,Q92888,P17252 7 +Alzheimers disease 0.2798602211042443 0.5590837607007781 0.5761045570781453 1.0 0.8477636165133683 63 P18859,O43678,P14406,P51970,P06576,O75380,P14854,O43676,Q9UDW1,P22695,P27361,P25705,P16615,O75306 14 +B cell receptor signaling pathway 0.3862312492731342 0.5509393474768459 0.5816752531854712 1.0 0.849058232472341 15 P36507,O15111 2 +Pancreatic cancer 0.360415800110891 0.4861390836279258 0.6268685579571358 1.0 0.9077056719219326 17 O15111,Q00534 2 +Bladder cancer 0.4311813241975486 0.4350788298215563 0.6635052093328655 1.0 0.9456255345610132 7 P36507 1 +Adipocytokine signaling pathway 0.3452097561891405 0.4048446744221392 0.6855916880752031 1.0 0.9517592181534238 17 O15111,P54619,P54646 3 +Olfactory transduction 0.4361670246867624 0.3949770719924689 0.6928598090473916 1.0 0.9517592181534238 5 P17252 1 +Long term depression 0.3685907129173282 0.3861859161725527 0.699358983505002 1.0 0.9517592181534238 13 P36507,P27361,P17252 3 +Gap junction 0.3242395524320566 0.376701743028362 0.706395267376893 1.0 0.9541607716061016 20 P36507,P17252,P04350 3 +Natural killer cell mediated cytotoxicity 0.3418186283437147 0.3565805895651046 0.7214058107578931 1.0 0.9672181610902124 16 P36507,P27361,Q16512,P17252,P63000 5 +Amyotrophic lateral sclerosis als 0.3669384727861006 0.3120285081530206 0.7550188578080337 1.0 0.9749240209567476 11 P07197 1 +Aminoacyl trna biosynthesis 0.2805042539500275 0.3105068651883735 0.7561755396473253 1.0 0.9749240209567476 33 P54136,P49591,Q9HA77,Q9Y285,P49589,A2RTX5,P41250,P23381,P49590,Q5T160,P47897,Q9BW92 12 +Nucleotide excision repair 0.2922889312687848 0.3061752724386137 0.7594711986458642 1.0 0.9749240209567476 26 P18074,P28340,P15927,P35244,Q92759,P19447,Q9NR33,P35251,P54725,Q07864,Q13620,Q9Y2S7 12 +Ribosome 0.2500103880694527 0.2664581663606308 0.7898863734925718 1.0 0.9785467012147816 74 P39023,P62841,P61247,P62854,P61254,P62081,P46778,P46777,P18621,P50914,P83731,P08865,P25398,P84098,P62917,P62899,P62266,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635,P62913 26 +Mapk signaling pathway 0.2592133781494651 0.2536252552167198 0.799785083616054 1.0 0.9785467012147816 46 P16949,Q13043,P36507,O15111,Q9BQ95,P17252 6 +Tgf beta signaling pathway 0.3347816987674268 0.2453007926552912 0.8062235380470353 1.0 0.9785467012147816 13 Q09472,Q13464,P27361,Q13485 4 +Toll like receptor signaling pathway 0.2953020539100726 0.2374311826902725 0.8123223009554947 1.0 0.9785467012147816 21 P36507,O15111 2 +Cysteine and methionine metabolism 0.3155354339318864 0.21761373754698 0.8277300799816467 1.0 0.9785467012147816 15 Q13126 1 +Chemokine signaling pathway 0.2728585223616399 0.2146290906483009 0.8300565113889462 1.0 0.9785467012147816 28 O15111,P27361,Q16512,P17252,P63000 5 +Melanogenesis 0.2992169711878055 0.2120694606081085 0.8320528447182307 1.0 0.9785467012147816 18 P36507,Q09472,Q13555,P17252 4 +Gnrh signaling pathway 0.3025795027011841 0.2044754411288973 0.8379819817032661 1.0 0.9785467012147816 17 P46734,P36507,Q13555,P27361,P17252 5 +Long term potentiation 0.2722863352197168 0.1070300368322876 0.9147651506702934 1.0 1.0 18 Q09472,P36507,Q13555,P27361,P17252 5 +Terpenoid backbone biosynthesis 0.3081073584710511 0.1039858628357431 0.9171805675679854 1.0 1.0 9 Q15126 1 +Mtor signaling pathway 0.2872494431572623 0.0936758950653858 0.9253666190108284 1.0 1.0 13 P27361,P42345,P54646,P62753 4 +Insulin signaling pathway 0.2383778873858673 0.084007654015157 0.9330503462588676 1.0 1.0 39 Q14254,P36507,P42345,P54646,P62753,P27361,P54619,Q9UPT5,P17252 9 +Colorectal cancer 0.2671664167916032 0.0693431566165483 0.944716474377953 1.0 1.0 16 P52701,P04637,P43246,P61586,Q13485,Q02750,P35222,Q9UJX6,P25054,P27361,P28482,P20585,P49841,P63000,P31751 15 +Jak stat signaling pathway 0.2849446273570809 0.0646141724932004 0.9484812002736712 1.0 1.0 10 Q09472,Q8N2W9,P40763,P22681,P42224,Q92793,O75925,Q06124,P31751 9 +Endometrial cancer 0.2670062930776058 0.056561464498446 0.9548945322514611 1.0 1.0 14 P35221,P04637,Q13418,P36507,Q02750,P35222,Q9UJX6,P25054,P27361,P28482,P49841,P31751,P62993 13 +Dorso ventral axis formation 0.265989240884632 0.0401928855859036 0.967939349528635 1.0 1.0 5 P62993,Q02750,P28482,P27361 4 +Proteasome 0.2314439511685329 0.0382630794830651 0.969477927520798 1.0 1.0 36 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,P49721,Q92530 9 +Wnt signaling pathway 0.2301023328428611 0.0256294922467404 0.9795528623811344 1.0 1.0 33 Q09472,Q13464,Q13485,O75116,Q13555,P17252,P63000,P67870,Q9HB71 9 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..01e188cf4eb6885bf651f108bd7f6b1abd3e3d28 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAR", "ADH5", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "APIP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BCR", "BDH2", "BIRC6", "BLM", "BLVRA", "BLVRB", "BPNT1", "BRCA1", "BRD8", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CAMK4", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDS2", "CFL1", "CFL2", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP5", "CHMP6", "CHORDC1", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT7", "CNOT9", "COASY", "COMT", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "EXO1", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FPGS", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTSE1", "GUSB", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPA1", "IMPDH1", "IMPDH2", "INPP4A", "INPP5K", "INPPL1", "IQGAP1", "IQGAP2", "IRAK1", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "KIDINS220", "L2HGDH", "LAMC1", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LIG1", "LIG3", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MAN1A1", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGAT2", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MLH1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYH10", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NF1", "NFAT5", "NIT2", "NLN", "NME1", "NME2", "NME3", "NNT", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NUDT12", "NUDT5", "OAT", "OCRL", "OGDH", "ORC3", "ORC5", "OTUD5", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS2", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKN1", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PUF60", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QPRT", "RAB13", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RELA", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHOA", "RICTOR", "RIPK1", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RSL24D1", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETD2", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORD", "SORT1", "SPCS2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TAF6", "TALDO1", "TARS", "TARS2", "TARSL2", "TBK1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TOLLIP", "TOMM40", "TOP3B", "TP53", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR5", "UCK2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "VAMP7", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37B", "VPS45", "VPS4A", "VPS4B", "WARS", "WARS2", "WASF2", "WBP11", "WDR61", "XAB2", "XIAP", "XPC", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB1", "ABCD3", "ACOX3", "ACTN1", "ACTN4", "AKT2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "APC", "APEX1", "ARHGAP5", "ARHGEF1", "ARPC4", "ATP2A2", "ATP5A1", "ATP5B", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAIAP2", "BLM", "BLVRA", "CACYBP", "CALD1", "CAMK2G", "CARS", "CARS2", "CBL", "CCNB2", "CDC23", "CDK2", "CDK6", "CHEK1", "CHUK", "COMT", "COX6B1", "COX7A2", "CREBBP", "CSNK2B", "CTNNA1", "CTNNB1", "CUL4B", "CYFIP2", "CYP51A1", "DCTN2", "DCTN4", "DHCR24", "DHFR", "DLG1", "DNA2", "DOCK1", "DTX3L", "DYNC1I2", "DYNLL2", "EBP", "ECSIT", "EP300", "ERCC2", "ERCC3", "ESPL1", "EXOC7", "EXOG", "EZR", "FADS2", "FARP2", "FARSA", "FDFT1", "FEN1", "FLOT2", "GARS", "GRB2", "GSK3B", "GTF2H4", "HARS2", "HMGB1", "HMOX1", "HMOX2", "HSD17B12", "ILK", "IQGAP2", "KDELR1", "LCMT2", "LIG1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MAPK3", "MCM3", "MCM4", "MCM5", "MCM6", "MIF", "MPG", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTOR", "MYH10", "NAMPT", "NCKAP1", "NDUFA11", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "ORC3", "PAK2", "PARP1", "PARP2", "PIAS1", "PIAS4", "PIGK", "PIP4K2A", "PKN1", "PLCG1", "PMVK", "POLD1", "POLDIP2", "POLE", "POLE4", "PPP1CA", "PRKAA2", "PRKAG1", "PRKCA", "PSMB2", "PSMC1", "PSMD11", "PSMD13", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSMF1", "PTPN11", "QARS", "RAC1", "RAD23A", "RARS", "RARS2", "RDX", "RFC1", "RHOA", "ROCK1", "ROCK2", "RPA2", "RPA3", "RPL10", "RPL11", "RPL14", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL3", "RPL31", "RPL37A", "RPL5", "RPL8", "RPS12", "RPS15", "RPS2", "RPS23", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "SARS", "SEC11A", "SLC25A10", "SLC25A4", "SLTM", "SMAD4", "SMC3", "SRP19", "SRP72", "SRP9", "SRPRB", "SSBP1", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "TARS2", "TARSL2", "TFAM", "TP53", "TPM3", "TPM4", "TPR", "TUBB4A", "TYMS", "UNG", "UQCR10", "UQCRC2", "VDAC1", "VDAC2", "WARS", "XRCC1"]} \ No newline at end of file diff --git a/msigdb_reactome/advanced/idx2term.json b/msigdb_reactome/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e022c231afdb92a4177cca5c9eb4434ac8310910 --- /dev/null +++ b/msigdb_reactome/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial protein import", "1": "Protein localization", "2": "Transport of small molecules", "3": "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "4": "Copi mediated anterograde transport", "5": "Selective autophagy", "6": "Copi independent golgi to er retrograde traffic", "7": "Intra golgi and retrograde golgi to er traffic", "8": "Organelle biogenesis and maintenance", "9": "Golgi to er retrograde transport"} \ No newline at end of file diff --git a/msigdb_reactome/advanced/plot_0.png b/msigdb_reactome/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..990748c07c960e0c5efc658b80f0e90fce0c243e --- /dev/null +++ b/msigdb_reactome/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:39383921d9d4e7c2d86eb1039458103ece3fec9bea52f069561a00ce774bfed7 +size 206815 diff --git a/msigdb_reactome/advanced/plot_1.png b/msigdb_reactome/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5060948f1408969ac0c460764f96d0a6fdefdcd5 --- /dev/null +++ b/msigdb_reactome/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8d29898913769c84c711fda74f384ed43e55ea27e8783a9fb0d3125066a68d98 +size 210844 diff --git a/msigdb_reactome/advanced/plot_2.png b/msigdb_reactome/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b116e8ee7cedfc35d9eedc4ac6021e2db4571ccb --- /dev/null +++ b/msigdb_reactome/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2fe722554867002b2b41442f5bd82083dd867d3d9b0810fc5a179f500c8ad7b4 +size 230397 diff --git a/msigdb_reactome/advanced/plot_3.png b/msigdb_reactome/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..e0af23cbe45fcb87e9e2aa95b213c45d1e592127 --- /dev/null +++ b/msigdb_reactome/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d24e41bc162ac6caa702e1c31f5318e31edd6fbe1cc2efa77ecce92459dcd8e +size 213474 diff --git a/msigdb_reactome/advanced/plot_4.png b/msigdb_reactome/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..05faaee8fa7425ce3858b68b7f77cbbe81fd4788 --- /dev/null +++ b/msigdb_reactome/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aeb84e0f7bb0177246a38e1f975a78f7ff1811dbf8af8438b6b50a205bb5046e +size 213334 diff --git a/msigdb_reactome/advanced/plot_5.png b/msigdb_reactome/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..98e175b51f0da94d523815354443323baace1d59 --- /dev/null +++ b/msigdb_reactome/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c48ef663a5339d1647055c61962cdad140925ee85b4c083226a29745b36c325 +size 210249 diff --git a/msigdb_reactome/advanced/plot_6.png b/msigdb_reactome/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a24dd82d2c3fff5b599349482571e1dc40974ab9 --- /dev/null +++ b/msigdb_reactome/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6a67cadd86294e96df74f68a1a8446e5571eff9ac4b1affabf25df64436fe43 +size 211299 diff --git a/msigdb_reactome/advanced/plot_7.png b/msigdb_reactome/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..aad03d1e6cc9e23ca813062d50b97f310ac95d1b --- /dev/null +++ b/msigdb_reactome/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d95b2136e1b669afbff00832958e9e2d61898145f237e4cd0ff6bf1416055aae +size 221175 diff --git a/msigdb_reactome/advanced/plot_8.png b/msigdb_reactome/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e903d680d840196e5e848c87344498c0d3f0c76b --- /dev/null +++ b/msigdb_reactome/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10aa7ec22d8a82e39a7be4ddc9f9b2432b957a6c06baf8f7cd9fd296b24c0b6d +size 223251 diff --git a/msigdb_reactome/advanced/plot_9.png b/msigdb_reactome/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4a33c88792dfaba316b67603604a888d3e5b2904 --- /dev/null +++ b/msigdb_reactome/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2586c1b4fed89c957513a7a9bc314396bbe73bd6eaac5c17df142e04cf78247f +size 213916 diff --git a/msigdb_reactome/basic/idx2term.json b/msigdb_reactome/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bc07bfdffda280ebee3464730b6b11d283ac0d8d --- /dev/null +++ b/msigdb_reactome/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial protein import", "1": "Protein localization", "2": "Transport of small molecules", "3": "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "4": "Copi mediated anterograde transport", "5": "Selective autophagy", "6": "Copi independent golgi to er retrograde traffic", "7": "Intra golgi and retrograde golgi to er traffic", "8": "Organelle biogenesis and maintenance", "9": "Golgi to er retrograde transport", "10": "Rhov gtpase cycle", "11": "Sensory processing of sound", "12": "Transport to the golgi and subsequent modification", "13": "Autophagy", "14": "Er to golgi anterograde transport", "15": "Cytoprotection by hmox1", "16": "Ion channel transport", "17": "Cholesterol biosynthesis", "18": "Anchoring of the basal body to the plasma membrane", "19": "Cilium assembly", "20": "Mitochondrial calcium ion transport", "21": "Sensory perception", "22": "Sensory processing of sound by outer hair cells of the cochlea", "23": "Aurka activation by tpx2", "24": "Diseases of mitotic cell cycle", "25": "Mhc class ii antigen presentation", "26": "Processive synthesis on the c strand of the telomere", "27": "Rho gtpase cycle", "28": "Regulation of plk1 activity at g2 m transition", "29": "Signaling by alk in cancer", "30": "Netrin 1 signaling", "31": "Muscle contraction", "32": "Peptide hormone metabolism", "33": "Mitochondrial biogenesis", "34": "Recruitment of numa to mitotic centrosomes", "35": "Recruitment of mitotic centrosome proteins and complexes", "36": "Cellular responses to stimuli", "37": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "38": "Rhou gtpase cycle", "39": "Signaling by braf and raf1 fusions", "40": "Cristae formation", "41": "Diseases of signal transduction by growth factor receptors and second messengers", "42": "Switching of origins to a post replicative state", "43": "Synthesis of pips at the golgi membrane", "44": "Cell cycle mitotic", "45": "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "46": "Sema4d in semaphorin signaling", "47": "Assembly and cell surface presentation of nmda receptors", "48": "Rhoa gtpase cycle", "49": "Fcgamma receptor fcgr dependent phagocytosis"} \ No newline at end of file diff --git a/msigdb_reactome/basic/plot_0.png b/msigdb_reactome/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..25b5ac2e2902b2153c5eaa71855845b49bc1fe96 --- /dev/null +++ b/msigdb_reactome/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:389e01ab649b87e430a2138307a0e21193fb9618b2f219c918590acb6d59a6d8 +size 138068 diff --git a/msigdb_reactome/basic/plot_1.png b/msigdb_reactome/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ab5373b112c4d45e3bdf14e01703b4fb7d532e30 --- /dev/null +++ b/msigdb_reactome/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2cd7b3a73b4efb5ecf2f45208211d540f86f1d8643eac52435a12dbbeba622e +size 135886 diff --git a/msigdb_reactome/basic/plot_10.png b/msigdb_reactome/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..4eca2a39bf41295614985108aea6eb9d74a39216 --- /dev/null +++ b/msigdb_reactome/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83e756fb3127fd23e3a20f15e026174561503f111803bbe96dc0f0cb302f22c4 +size 135343 diff --git a/msigdb_reactome/basic/plot_11.png b/msigdb_reactome/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..e01654ab92379e2e4451eb22d26340e1a379474b --- /dev/null +++ b/msigdb_reactome/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c3710396a31536538d228c6cc3105ac94ca9fe38b943360596472792b990a3b +size 141702 diff --git a/msigdb_reactome/basic/plot_12.png b/msigdb_reactome/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..698fe17c1468e579e7e9c33ae4c72a92a464da09 --- /dev/null +++ b/msigdb_reactome/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94e9cf50ba993ef50f142f96b0d509e6c5c62e1fb9d5e6e9a7491dfb7c92d3b6 +size 149645 diff --git a/msigdb_reactome/basic/plot_13.png b/msigdb_reactome/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..ff73487f633bfede08422a4d4d23a022d83ff570 --- /dev/null +++ b/msigdb_reactome/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:28a166d635ca1b4caa291ef746b8c4de7b207fa390e165b2ea0ebe34930bb1a0 +size 135662 diff --git a/msigdb_reactome/basic/plot_14.png b/msigdb_reactome/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..e554ec3eb59c03f541b19f136a18bcab917edb64 --- /dev/null +++ b/msigdb_reactome/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0332a800acdcfab35e4e24f783f18d8888b16613aed2e0e7cc43648b60f3521e +size 144675 diff --git a/msigdb_reactome/basic/plot_15.png b/msigdb_reactome/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..ad6c6af9d71d3b4f953e131df8190ba0033d27d0 --- /dev/null +++ b/msigdb_reactome/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a25d6f773b61a3149323f795f8f15f4b33adfa95dd78a0193d87dcab0809b515 +size 143395 diff --git a/msigdb_reactome/basic/plot_16.png b/msigdb_reactome/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..716925b0545d0590f7a46748f549bfdd3ceb6875 --- /dev/null +++ b/msigdb_reactome/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:174c85d12589f6a49df6936c1f3fc9df4d5872b36dd396751076ce4995f092be +size 129800 diff --git a/msigdb_reactome/basic/plot_17.png b/msigdb_reactome/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..e6a1065440d5424f91518b3eb1eab106f671815d --- /dev/null +++ b/msigdb_reactome/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be5e5a3e0a6c607a2165e9474087061b8e1dbfa01be5d7541d1fd9798a009c34 +size 136081 diff --git a/msigdb_reactome/basic/plot_18.png b/msigdb_reactome/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..99b7fc1eb6de782098e62132ce247b8bb5f498b5 --- /dev/null +++ b/msigdb_reactome/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d5b3fc1f33761226b33052bf9fffbdeebb971822801727e4caa64adf8259603 +size 140689 diff --git a/msigdb_reactome/basic/plot_19.png b/msigdb_reactome/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..d0d1dbb394dbfaac37c20c25c0bb7cdc2919c843 --- /dev/null +++ b/msigdb_reactome/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cefc4c0df5d0f7b72f5e1100f516c9a706a9da1f5b5c0d8c82dc6a587ed1439b +size 138138 diff --git a/msigdb_reactome/basic/plot_2.png b/msigdb_reactome/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..fca145542c30e6ce708e32c001f6fbd1bf4a04f4 --- /dev/null +++ b/msigdb_reactome/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06acc55d83c74e02162fd24c0733cf79a83d9c046963fc514eb27e0a531b65be +size 147402 diff --git a/msigdb_reactome/basic/plot_20.png b/msigdb_reactome/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..28cad9c3d9d80fd115924be4b0e1e0e85c55874d --- /dev/null +++ b/msigdb_reactome/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38c84c9eb451c09ae8a2281083d761e975b1f3e97f9b7067cc30e6dcb962cb0e +size 134893 diff --git a/msigdb_reactome/basic/plot_21.png b/msigdb_reactome/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..63eee26691981ff7a4975d13cb1256dbcae8ffa4 --- /dev/null +++ b/msigdb_reactome/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f769f125ea915d64436b35263c65d680fb435ae47e097575b39f877938100f96 +size 134695 diff --git a/msigdb_reactome/basic/plot_22.png b/msigdb_reactome/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..706eb1a7040b1c396908ec23e6e2ec56b86a694d --- /dev/null +++ b/msigdb_reactome/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ce1674849c43563b24d6e703515482e72f1b65dd542e3e989f3d8169b6357d8 +size 143555 diff --git a/msigdb_reactome/basic/plot_23.png b/msigdb_reactome/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..c0c4090e3cb4ccbf77804383139a9efe85de8b2b --- /dev/null +++ b/msigdb_reactome/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a673e05bcdfe76ee5a85767aa5c73372a4e7e424ae95db422e631d49ec5ad586 +size 138011 diff --git a/msigdb_reactome/basic/plot_24.png b/msigdb_reactome/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..3356ecab79bcdaf0981d1d0d2986876c11ee4a5c --- /dev/null +++ b/msigdb_reactome/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29830f15134a9954349e52c664d561076d1691f1f6e05ef63e918d6c477c6827 +size 138177 diff --git a/msigdb_reactome/basic/plot_25.png b/msigdb_reactome/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..c0e36a54d0ffca5e3c3261db5147987e1b5cd116 --- /dev/null +++ b/msigdb_reactome/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4f4d0f8abae2a547f37220f5ea87dea83ef91a9bcfcf0aa209e183e2fe95ff3 +size 145887 diff --git a/msigdb_reactome/basic/plot_26.png b/msigdb_reactome/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..f55267350c1048bc4fe064cda06637de16e3b291 --- /dev/null +++ b/msigdb_reactome/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:681ae7029db34808d14e9d06473a17e8bdb658b054d6e722c5420d6df68a7f84 +size 137448 diff --git a/msigdb_reactome/basic/plot_27.png b/msigdb_reactome/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..038915b195ff6a862043cd58f4c7407b872dffc9 --- /dev/null +++ b/msigdb_reactome/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e1eb7b146a8cf5343344ed9f055eb1a238d856e5b586e88fcf9482e7cc8c667 +size 141245 diff --git a/msigdb_reactome/basic/plot_28.png b/msigdb_reactome/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..bd7165c69b5a5b5e5f479e0f9d69834b9f348cde --- /dev/null +++ b/msigdb_reactome/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc15126b9cbf95e6e95d37b68440526e845fea4a7846fbf698433e69edaa9cff +size 140803 diff --git a/msigdb_reactome/basic/plot_29.png b/msigdb_reactome/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..ed1295c722753b3cf4d238f02d24f3ca7da2c5c7 --- /dev/null +++ b/msigdb_reactome/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:906439a070f734120a536a2d2097d1b9bbf1269f61c0456b30d21abc54f07f31 +size 142163 diff --git a/msigdb_reactome/basic/plot_3.png b/msigdb_reactome/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4fbd27e963323415a3e7a67f236353e851b0cde7 --- /dev/null +++ b/msigdb_reactome/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3504cb0559f969e5a18ac59c153a24b01034cced75a5fbd297201f0a2fb56ca +size 145268 diff --git a/msigdb_reactome/basic/plot_30.png b/msigdb_reactome/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..eaafa8ce20b951ca27e1e71acf8a963a7d81b600 --- /dev/null +++ b/msigdb_reactome/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dea5386efd7b3ec163c0840ed2e043152ecc138fb86855f28bd33151cd673f35 +size 132477 diff --git a/msigdb_reactome/basic/plot_31.png b/msigdb_reactome/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..8f89e5b12621eb4621f2f9c94a0a5ca3454ce41e --- /dev/null +++ b/msigdb_reactome/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62f2eafb9b9f8708370df89fc308b229e2d46eca3a518478d67fe145e1907ce8 +size 138117 diff --git a/msigdb_reactome/basic/plot_32.png b/msigdb_reactome/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..cb2c47864dc0b3077988d7df74c4751b78ce466b --- /dev/null +++ b/msigdb_reactome/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29baca28cd7093ddae14b41d39cca1f58a325e2e55aff521dbbcdb30246fe92c +size 135418 diff --git a/msigdb_reactome/basic/plot_33.png b/msigdb_reactome/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..0ebc70bfbd4ff64c9a7cab2ee885f08e2aeba382 --- /dev/null +++ b/msigdb_reactome/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c12ac855199d9a958dda9f7d9fd1f989703accb811d78af76fbc8b8b1a71d684 +size 136620 diff --git a/msigdb_reactome/basic/plot_34.png b/msigdb_reactome/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..881078c83f8f269b849c134bd92ba6c3a6c4e61b --- /dev/null +++ b/msigdb_reactome/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5ff37dcae3ff6389741931182d6363efcac2cb303757f76e6438e3065053dd7 +size 145508 diff --git a/msigdb_reactome/basic/plot_35.png b/msigdb_reactome/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..ecaf9350c553af3e66c63286423dd84061ec58a3 --- /dev/null +++ b/msigdb_reactome/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5a0993ed00c8ac07d62458f50e56e51a7a6d635bac2521d42973a9e839b43e8 +size 146234 diff --git a/msigdb_reactome/basic/plot_36.png b/msigdb_reactome/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..66b85c0267fc7f59ede8ad107438bbfba56ce9af --- /dev/null +++ b/msigdb_reactome/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2dffb88e79d0054f3a90fe7b5649a9ba5978a4e2a778478d263d34050f50deb +size 138970 diff --git a/msigdb_reactome/basic/plot_37.png b/msigdb_reactome/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..3859436efd234ffcfba40a7f164b140dc9b47dce --- /dev/null +++ b/msigdb_reactome/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c67da680004042afda3a777dc3ea7a11ebcf9b93a3b01edb6b50a55402f9d79 +size 148067 diff --git a/msigdb_reactome/basic/plot_38.png b/msigdb_reactome/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..a5c27bc9ffa120a4bea5f9d98aebe98920746e38 --- /dev/null +++ b/msigdb_reactome/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db7ab6c7e1762e253195dc27308e1656594bc72e0b03728ed2a2ecf2e34ab9be +size 132404 diff --git a/msigdb_reactome/basic/plot_39.png b/msigdb_reactome/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..595d6e9c3c36f74cfcd16e8cb9b649931f6106f0 --- /dev/null +++ b/msigdb_reactome/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e54c774e88fcd0c8b686143b0b39deaac1156c3b78b0a10ef3539bc537523ee0 +size 146028 diff --git a/msigdb_reactome/basic/plot_4.png b/msigdb_reactome/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..840f3098463396dc3700e25804c1d017b07e284f --- /dev/null +++ b/msigdb_reactome/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b50ee6f6af6ce3df2f299ed84b1204773614a3958da80d76b24afb6fcde96ac +size 144853 diff --git a/msigdb_reactome/basic/plot_40.png b/msigdb_reactome/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..7bfbf4548a1255a4ac514b0a0dd7f9b3c097815e --- /dev/null +++ b/msigdb_reactome/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37e802e5d947f570aeed4575bcb18a0a473fbb246dcb99dee3a1a3bd54c070ae +size 130761 diff --git a/msigdb_reactome/basic/plot_41.png b/msigdb_reactome/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..3827a2d4ce3d0cab2b1b6c4d742ab6498300dfcc --- /dev/null +++ b/msigdb_reactome/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ebcc6e26ac29dcd0d62bd2f7bd01b27bf15fd2544921e47da303a185e106948 +size 153172 diff --git a/msigdb_reactome/basic/plot_42.png b/msigdb_reactome/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..b79cbc5584132f9d5773191e3f1b61ae7871e2f2 --- /dev/null +++ b/msigdb_reactome/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:802628468aff40d7bf2e48f6fa9c7e001c406d03406700ece48c3a94e5ab2c5d +size 150333 diff --git a/msigdb_reactome/basic/plot_43.png b/msigdb_reactome/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..6dc1a755001c2dd00ca550dc903affbdfc72446f --- /dev/null +++ b/msigdb_reactome/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db26d8247d1c8a93b946a8b189f421392a55acdab5a57465a6b81abc46e6eaf4 +size 143100 diff --git a/msigdb_reactome/basic/plot_44.png b/msigdb_reactome/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..09e3fd15a6e86283d1cab3d7882e0ff905c3964f --- /dev/null +++ b/msigdb_reactome/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1ade509e422255119b2b8bf7619f44cdb0c34262ccd7f38bbd14c9f0e30abc4 +size 139633 diff --git a/msigdb_reactome/basic/plot_45.png b/msigdb_reactome/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..f6c54c10419bed8495a9e487ae8ea31c879cdf37 --- /dev/null +++ b/msigdb_reactome/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68eed4a777ce9e7ffd7b2aab5b9903fdde886dc7b898b503a96beed845d6bec5 +size 139540 diff --git a/msigdb_reactome/basic/plot_46.png b/msigdb_reactome/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..8bdb6d32d5af8b838638d25ae4fa8325bf2a1692 --- /dev/null +++ b/msigdb_reactome/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:28754b9642e3c5794e73c1db2bb3baf5a4160405aa6deeeb42ea47ab6d7802bb +size 139386 diff --git a/msigdb_reactome/basic/plot_47.png b/msigdb_reactome/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..6e75fc1f7818663ee2c1e05f3d7bf31cd1c68b98 --- /dev/null +++ b/msigdb_reactome/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2cb4eebe750cddfa3c56ec59eb385732a84fcdb7a70f20eea0ca8dccab8b3241 +size 145287 diff --git a/msigdb_reactome/basic/plot_48.png b/msigdb_reactome/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..ca6f22b045c4945912aea8ba6cf74df3ca2b535f --- /dev/null +++ b/msigdb_reactome/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac7b9b48f56411df13b9c02899b32ef181d18969c49ac7733037c1e2adf2642c +size 142184 diff --git a/msigdb_reactome/basic/plot_49.png b/msigdb_reactome/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..6afe3d175d2db08b87311162f042b4ca562bc859 --- /dev/null +++ b/msigdb_reactome/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3f256accfd624c84649a34fcf3a8c7f2b5e06ce1a532e313d3db33ccb1e02e3 +size 147425 diff --git a/msigdb_reactome/basic/plot_5.png b/msigdb_reactome/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..804886e109d98b4916bed700c9e3913a56ac5ac2 --- /dev/null +++ b/msigdb_reactome/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0372b3f16adc1709263cbf4bc872a00fbde79bb21f0e81533287317a4459cf2 +size 138292 diff --git a/msigdb_reactome/basic/plot_6.png b/msigdb_reactome/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..161c73b08f064a7ec22be00824fafe72efa786e9 --- /dev/null +++ b/msigdb_reactome/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d00dc57acbddc2315f04758f2944b38bcee59312585167d93efd6800eb32e953 +size 143964 diff --git a/msigdb_reactome/basic/plot_7.png b/msigdb_reactome/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0b3b413da708bf6ffc0f7e1f6b1d11173b0f9fe0 --- /dev/null +++ b/msigdb_reactome/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38a206490e4fc8dff7bf08139e4631d06ad454482c77f8dadd6d587cf5e272b6 +size 148170 diff --git a/msigdb_reactome/basic/plot_8.png b/msigdb_reactome/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..ea8542016f99fb13ef63be9dfa5d657bcb798c0d --- /dev/null +++ b/msigdb_reactome/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78f2d5f6a019d5603d9cb260fd8aafe8dda65229e0122cf525d95c6af10ae144 +size 153694 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..d70ac77238e48859f9a973ff527af73825e52b77 --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:26e9b55f83a619e4263c99a1bb55ae7c2dc45797a116fa0aa90686d92863560f +size 144832 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2273e504f3dee7dd1eb53ff3813b45b08aebb524 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46b3891d50332a086a01f01b574d3c65c18c86dc30edad6e22a58e10921d0160 +size 182440 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a702887bae5efadd8c5e533c1de3e1dc157e7cd2 --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,23 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Mitochondrial protein import 13 32 3.753743965602709 0.0001742128119763 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.000149819169886 0.0023478710954916 1.2845224898827528e-06 6.252354807206027e-07 +Protein localization 21 68 3.5506932742882342 0.0003842179104001 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 0.0004679347955422 0.0113075649407646 0.0001677661776841 1.3016376864054743e-06 +Transport of small molecules 21 145 3.016740642026478 0.0025550832254643 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 4.599131934159576e-05 0.0008750781828948 0.0003256149682517 0.0099258846059272 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 5 32 2.776679982177853 0.0054917220368246 10.99514563106796 30.575242718446603 0.1584518755541417 0.6126046167689052 6.479989791445523 1.8065868396091345 1.0359782039154073 0.3387863879536805 0.1955906255262107 0.0734859631006396 0.1048323445251165 0.0256439269364036 +Copi mediated anterograde transport 20 50 2.6660800179689863 0.0076741424792665 14.364077669902912 53.29368932038835 0.4832864212749729 0.5898511157237575 6.303679837135847 4.572358803691129 1.0202251873333663 0.3614704266753352 0.0632391282058976 0.0527430730742316 0.0646269414847783 0.0111044401007954 +Selective autophagy 8 33 2.613565533879048 0.00896028978864 7.315533980582524 31.50728155339806 0.9304065525388932 0.4028226131520862 3.350474746292583 3.101431769008479 1.074438805028982 0.3502038092942861 0.0380395748305272 0.0257953084689971 0.0789974698724344 0.0014020336345134 +Copi independent golgi to er retrograde traffic 5 28 2.523836498214593 0.0116081904437261 8.053398058252426 27.12135922330097 0.302798844042666 0.6258770271233919 3.9403394347399954 2.2597856451930913 0.8982376608905671 0.3350370934950194 0.1880892294635792 0.0681167311872175 0.0949405615621671 0.0210947346086547 +Metabolism of porphyrins 3 9 2.417809964041914 0.0156142290307328 2.766990291262136 9.186893203883496 1.2638611374915407 0.2204767139400954 1.3861582272503026 1.170645435718008 1.0950295956895657 0.2541910601955712 0.0027065615852008 1.6660935716793687e-05 0.00062382482254 0.0010238181908857 +Intra golgi and retrograde golgi to er traffic 35 88 2.279161361935761 0.0226574749816259 23.762135922330096 91.83252427184466 0.7836914286379623 0.5449079285432085 8.961715947260837 10.213669235838784 1.1120768516172963 0.4008074869702365 0.2028967221549326 0.2475305235196633 0.0731324962931605 0.0587776998116606 +Organelle biogenesis and maintenance 23 91 2.2689318704793795 0.0232724692664478 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.7148624146480367 0.251265953726846 0.0135089797627271 0.0029273545586345 +Golgi to er retrograde transport 29 71 2.246126076404136 0.0246959335174035 16.92233009708738 70.53883495145631 0.4559805501598206 0.6345143601474961 7.275693434924061 5.280109829133333 0.9044409230983104 0.3556018909943214 0.0982812904210197 0.0964752293748221 0.0604720542414166 0.024357569866123 +Rhov gtpase cycle 7 15 2.2360221818929302 0.0253503181846874 4.813106796116505 15.75242718446602 -0.1618042508452442 0.6366995947711929 3.201413986485727 2.239727127111961 0.7246631148482161 0.2858658906469543 0.1495431827221669 0.284754537798848 0.0520565373494006 0.0888289826938022 +Sensory processing of sound 9 18 2.2180630607293264 0.0265505330193118 6.407766990291262 17.59223300970874 -0.1979151622355178 0.6784882163123832 4.008938782183972 1.606642118569903 0.6752876378754417 0.2791249623345367 1.0 1.0 0.0720513532108381 0.0435237537141962 +Transport to the golgi and subsequent modification 11 75 2.2180283481090752 0.0265528996057393 20.604368932038835 77.1626213592233 0.4958457957496105 0.6299790557050085 8.044251420264837 7.0373663516482345 0.9638132242129624 0.3700222187340509 0.1485717214577993 0.1666719780928332 0.0682104000582474 0.0574903803931482 +Iron uptake and transport 4 17 2.151562659151136 0.0314318157725699 4.089805825242719 17.9126213592233 1.0360420001787272 0.323786301352462 2.0477771422769826 0.9863810102632052 1.0014322629164618 0.2971986354372174 0.0006916240201539 0.00553293278753 0.0020925837152473 0.0359117122080593 +Autophagy 9 51 2.144936916406309 0.0319578911162667 10.618932038834952 49.09466019417476 0.5991637048381673 0.5478738847433878 5.048592116085888 6.4120843612202885 0.9575127000026346 0.3634200031879806 0.1204838304307548 0.1266587422518154 0.2075596517244451 0.0523560798520111 +Er to golgi anterograde transport 10 71 2.133699286982905 0.0328674044813181 19.152912621359224 74.15776699029126 0.4357486981835305 0.6456866134420882 7.637631429097237 6.107600140782552 0.9360192475456132 0.3613336360589621 0.1189662776726985 0.1245492832104317 0.0932188412403147 0.0500122262489322 +Degradation of cysteine and homocysteine 1 6 2.1023206500076568 0.0355251968633951 1.104368932038835 4.262135922330097 0.3691477479603587 0.5071047029231757 1.1705447822232695 0.954917421820334 0.8661767879896388 0.2879668883059369 1.0 0.0055563644779973 0.0328731354880699 0.113339965404402 +Cytoprotection by hmox1 7 67 2.085133193250612 0.0370572119875469 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 0.0911729862972215 0.0871630557793903 0.0051861618207084 0.0181005697744452 +Sulfur amino acid metabolism 3 12 2.083167605745879 0.0372359487648972 2.203883495145631 9.817961165048544 0.6199361525903814 0.458076830061787 1.563287693807856 1.3396013457301907 0.7876168891442106 0.2726832305457685 1.0 0.0011273462404087 0.0153906222854723 0.020271757680103 +Ion channel transport 6 25 2.012419539250536 0.0441757304967536 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.3163996086563202 0.183361016235644 0.0143895951598155 0.1042683327750613 +Collagen formation 3 13 1.9777953596143905 0.0479517972045384 3.941747572815534 12.990291262135925 0.2345829931835236 0.5128668628634813 2.3195046454702752 1.083818721909935 1.0068208618616714 0.3116436276322541 0.1843129003022452 0.3439334989552355 0.2887846572413305 0.1653068273939545 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1164cefcf8d2d7520dfe371b6c2d2d4376176caf --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 1413, + "title": "Average number of proteins per term", + "value": 20.15286624203822 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..db349228360cad3d43e558c1b0a288d04a2ad0c5 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4893aff18b4da1bc47eafaa273bfb1b7eae5fbb4 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,535 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial protein import 0.7182435402619275 3.7537439656027094 0.0001742128119763 0.2182217513579316 0.0137873011307534 32 O60830,Q9Y5L4,Q99595,O43615,Q8N4H5,Q9Y5J9,Q9NX63,P12235,P21796,Q9NS69,O75390,Q13505,Q10713 13 +Protein localization 0.5357793642883409 3.5506932742882342 0.0003842179104001 0.4189998303024992 0.0193892824069769 68 O60830,Q99595,O43615,Q9Y5J9,P21796,P40855,O75381,Q9NS69,O75390,Q8N4H5,P50542,O15254,P09601,Q08426,Q10713,O43681,P51648,Q9Y5L4,Q9NX63,P12235,Q13505 21 +Proton coupled monocarboxylate transport 0.9638698118841406 3.2861755179451 0.0010155770688999 0.7620606747921598 0.0298960499657433 2 P35613 1 +Transport of small molecules 0.4100127391033706 3.016740642026478 0.0025550832254643 0.9730818047967394 0.0456611846064231 145 Q14997,P30519,Q70HW3,Q93050,P21796,P35613,Q9Y487,P08183,Q8WTV0,P45880,Q9Y5K8,P09601,Q9HD20,P55036,Q10713,Q96PU5,Q9UBX3,P49721,P12235,Q8NB49,P53985 21 +Sulfide oxidation to sulfate 0.9431170787936418 2.8042549121793487 0.0050433014207684 0.999210582561494 0.0712618490754585 3 Q9UBX3 1 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5836402432894393 2.776679982177853 0.0054917220368246 0.999582484509475 0.0760765023336596 32 Q9UJW0,Q96FJ2,P31948,Q13409,Q13561 5 +Abc transporters in lipid homeostasis 0.8262167811286983 2.669074562675071 0.0076060563089432 0.9999793632792804 0.0951189765193303 2 P40855 1 +Copi mediated anterograde transport 0.4909326775789816 2.6660800179689863 0.0076741424792665 0.9999812700169968 0.0951189765193303 50 Q9UJW0,P24390,P48444,P83436,Q96FJ2,Q14789,P04350,Q13409,P52907,P61923,P47755,O15498,Q99747,Q13561,Q01082,O60763,Q08379,Q9Y3B3,P49755,Q13813 20 +Attachment of gpi anchor to upar 0.8208420424007159 2.644045935484139 0.0081921537742817 0.9999910440104546 0.0997889076125869 2 Q92643 1 +Selective autophagy 0.557387898197004 2.6135655338790476 0.00896028978864 0.999997003163178 0.1072956734860033 33 Q8N4H5,P08670,Q96FJ2,P21796,P54619,Q9NS69,P04350,Q13409 8 +Transport of bile salts and organic acids metal ions and amine compounds 0.8849602831447149 2.5587237689329503 0.0105057182787047 0.999999669647935 0.1125165340307881 3 P35613 1 +Nef and signal transduction 0.7978501045088118 2.536162683904686 0.0112074655790546 0.999999878767916 0.1125165340307881 2 P63000 1 +Copi independent golgi to er retrograde traffic 0.5770607662149765 2.523836498214593 0.0116081904437261 0.9999999316290116 0.1125165340307881 28 Q9UJW0,Q96FJ2,Q13409,P04350,Q13561 5 +Formation of fibrin clot clotting cascade 0.8613912273348243 2.4572238389044916 0.014001541543434 0.9999999977760684 0.1213753263857195 3 P42785 1 +Metabolism of porphyrins 0.8283883183139894 2.417809964041914 0.0156142290307328 0.9999999997799064 0.1318116193099562 9 P53004,P09601,P30519 3 +Heme degradation 0.918910474810926 2.3645862296573186 0.0180502248050817 0.9999999999933604 0.1435582341110878 4 P30519,P09601 2 +Intra golgi and retrograde golgi to er traffic 0.4026653915956631 2.279161361935761 0.0226574749816259 0.9999999999999912 0.1702926178140291 88 Q10472,Q9UJW0,P24390,P48444,P51151,Q9H2M9,P83436,Q96FJ2,P33908,Q13409,P04350,O00139,O95235,P52907,P61923,P47755,Q6NUQ1,O15498,O43237,Q99747,Q13561,P33176,Q9H0B6,Q8IWJ2,Q99661,Q9NRW7,Q9P2W9,Q9BW19,Q9NS87,Q9Y496,Q8TBA6,O60333,Q9Y3B3,Q8N1B4,P49755 35 +Organelle biogenesis and maintenance 0.4015736762706502 2.2689318704793795 0.0232724692664478 0.9999999999999964 0.1718534341140853 91 Q96FJ2,O75964,P54619,Q04837,Q13409,P04350,P23258,Q99996,Q15019,Q9NVH1,P54646,Q10713,Q13561,O75695,Q00059,P00367,P06576,P56134,Q9UPT5,P17252,P18859,Q9NX63,Q13505 23 +Golgi to er retrograde transport 0.414259188018446 2.246126076404136 0.0246959335174035 0.9999999999999996 0.1767277298280506 71 Q10472,Q9UJW0,P24390,P48444,Q9H2M9,Q96FJ2,P04350,Q13409,Q9UBF2,O00139,O95235,P52907,P61923,P47755,Q6NUQ1,O43237,Q99747,Q13561,P33176,Q9H0B6,Q99661,Q9P2W9,Q9BW19,Q9NS87,Q9Y496,O60333,Q9Y3B3,P63167,P49755 29 +Rhov gtpase cycle 0.6767938484080996 2.2360221818929302 0.0253503181846874 0.9999999999999998 0.1798168228003756 15 Q9NNW5,Q13177,P06753,Q03001,Q16512,Q13813,P67936 7 +Sensory processing of sound 0.6296502979433551 2.2180630607293264 0.0265505330193118 1.0 0.1821322676840278 18 P35241,Q9Y2J2,P52907,Q01082,P15311,P47755,Q14651,P26038,Q13813 9 +Transport to the golgi and subsequent modification 0.4061049533011802 2.2180283481090752 0.0265528996057393 1.0 0.1821322676840278 75 Q9UJW0,P24390,Q08379,Q96FJ2,Q14789,Q9Y3B3,P55735,P33908,P04350,Q13409,Q13561 11 +Iron uptake and transport 0.6332553547169287 2.151562659151136 0.0314318157725699 1.0 0.201591518514665 17 Q93050,P09601,Q9Y487,P30519 4 +Autophagy 0.4356084304108076 2.144936916406309 0.0319578911162667 1.0 0.201591518514665 51 Q8N4H5,P08670,Q8WUX9,Q96FJ2,P21796,P54619,Q9NS69,P04350,Q13409 9 +Phase 0 rapid depolarisation 0.7154374440131412 2.1385878527242252 0.0324690621538641 1.0 0.2030034726699558 2 Q13555 1 +Er to golgi anterograde transport 0.4049258617496797 2.133699286982905 0.0328674044813181 1.0 0.2031067436168971 71 Q9UJW0,P24390,Q08379,Q96FJ2,Q14789,Q9Y3B3,P55735,P04350,Q13409,Q13561 10 +Degradation of cysteine and homocysteine 0.8250228018255928 2.1023206500076568 0.0355251968633951 1.0 0.2114110544161939 6 Q9UBX3 1 +Cytoprotection by hmox1 0.4056417729386866 2.085133193250612 0.0370572119875469 1.0 0.2172690478771944 67 Q14997,P30519,Q8TCT9,P09601,P14854,P55036,P53004 7 +Sulfur amino acid metabolism 0.7008209364036297 2.083167605745879 0.0372359487648972 1.0 0.2174148578710734 12 Q13126,Q9UBX3,Q9Y6N5 3 +Nicotinamide salvaging 0.767002307336049 2.0392588013556243 0.0414242050807989 1.0 0.2360177491095519 3 P43490 1 +Ion channel transport 0.5314668172788204 2.0124195392505357 0.0441757304967536 1.0 0.2476996317139398 25 Q96PU5,Q9Y5K8,Q93050,Q9HD20,Q8NB49,Q9Y487 6 +Disinhibition of snare formation 0.7584639538775552 2.0005709669276963 0.045438644976222 1.0 0.2510566251040083 3 P17252 1 +Collagen formation 0.6625245985515902 1.9777953596143905 0.0479517972045384 1.0 0.260895633300839 13 Q32P28,Q03001,O60568 3 +Methionine salvage pathway 0.8241275705927971 1.976722271857511 0.0480730318759534 1.0 0.260895633300839 4 Q13126 1 +Displacement of dna glycosylase by apex1 0.7529868578255599 1.975681044188165 0.0481909131574798 1.0 0.260895633300839 3 P13051,P27695 2 +Vitamin d calciferol metabolism 0.8207539558904616 1.9626428023730296 0.0496876935656986 1.0 0.2659420871527737 4 P04062 1 +Sema4d mediated inhibition of cell attachment and migration 0.7490327256086192 1.957677123457156 0.0502679112407109 1.0 0.2680322965400927 3 P63000 1 +Cholesterol biosynthesis 0.5859027221653436 1.9499306407141548 0.0511843864948531 1.0 0.26986394819861 18 P37268,Q13907,Q15126,Q15125,Q16850,Q15800,Q15392 7 +Anchoring of the basal body to the plasma membrane 0.4936700276041149 1.9452410030148788 0.0517459790234853 1.0 0.2718106630490139 29 P17252,Q13561,Q13409,P23258,P04350,Q99996,Q15019 7 +Cilium assembly 0.4084812971638705 1.9290394673788984 0.05372596276995 1.0 0.2790984757130124 54 O75695,P17252,Q96FJ2,Q13561,Q10713,Q9UPT5,Q13409,P23258,P04350,Q99996,Q15019 11 +Mitochondrial calcium ion transport 0.6220378828033931 1.9259173809760148 0.0541146908158971 1.0 0.2800881249921709 15 P45880,P21796,Q96TA2,Q10713,Q9UJZ1 5 +Metabolism of folate and pterines 0.7221328204410908 1.919256717543114 0.0549518527519017 1.0 0.283383094665829 9 Q9H2D1 1 +Sensory perception 0.4959211581258241 1.9108143900489072 0.0560284377822404 1.0 0.2859260469781798 28 P35241,P49354,Q9Y2J2,P52907,Q01082,P53582,P15311,P50579,P47755,Q14651,P17252,P26038,Q13813,Q6NUM9 14 +Transport of inorganic cations anions and amino acids oligopeptides 0.7321755776687467 1.887962772283896 0.0590309483850988 1.0 0.2952258669277467 8 Q70HW3 1 +Dcc mediated attractive signaling 0.7318643819238754 1.87917497076854 0.060220606023652 1.0 0.2952258669277467 3 P63000 1 +Synthesis of very long chain fatty acyl coas 0.751681576980995 1.8771193120707184 0.0605017430980798 1.0 0.2952258669277467 7 Q4G176 1 +Sensory processing of sound by outer hair cells of the cochlea 0.6420416611831331 1.866494798882755 0.061972171065213 1.0 0.2952258669277467 13 P35241,Q9Y2J2,Q01082,P15311,Q14651,P26038,Q13813 7 +Synthesis of pips at the er membrane 0.7267025089605681 1.8554698108208625 0.063529166392358 1.0 0.2970662273544269 3 P42356,Q13614 2 +Aurka activation by tpx2 0.4725430991874841 1.8304823395782508 0.0671778452096423 1.0 0.3062009525200793 30 P17252,Q13409,P23258,P04350,Q99996,Q13561,O75330 7 +Diseases of mitotic cell cycle 0.6114068422652834 1.7932599238014952 0.0729313723222973 1.0 0.3251480033754603 14 Q9H1A4,Q9UJX5,Q00534,P24941,Q9UJX4,Q9UJX2 6 +Mitophagy 0.6455787545745646 1.792461700190344 0.0730590389676062 1.0 0.3251480033754603 12 P21796,Q9NS69 2 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.711288296045634 1.7844129671298126 0.0743565855391477 1.0 0.3278296283222043 3 P63000 1 +Pink1 prkn mediated mitophagy 0.6940925233943296 1.783683578334146 0.0744750960307343 1.0 0.3278296283222043 9 P21796,Q9NS69 2 +Nicotinate metabolism 0.7632357945030428 1.7751474559621094 0.0758735429576658 1.0 0.3329481869539806 5 P43490 1 +Mhc class ii antigen presentation 0.3896425037591232 1.77184515605307 0.0764202644375813 1.0 0.3334037749456673 56 Q9UJW0,Q96FJ2,P50570,P55735,P04350,Q13409,O00139,O95235,Q9Y6G9,P52907,P47755,O43237,Q13561,P33176,Q9H0B6,Q99661,Q9NS87,Q9BXW6,Q9Y496,P63167,Q15436 21 +Ionotropic activity of kainate receptors 0.7066905615292612 1.7631429405150356 0.0778763844854397 1.0 0.3375439609752343 3 Q12959,Q15334 2 +Nrcam interactions 0.7066905615292612 1.7631429405150356 0.0778763844854397 1.0 0.3375439609752343 3 Q12959,Q15334 2 +Processive synthesis on the c strand of the telomere 0.639026832458073 1.757503991822735 0.0788319420432155 1.0 0.3404204412909566 12 P28340,P15927,P54132,P35244,P51530 5 +Creatine metabolism 0.7042921515622926 1.7520342017588444 0.0797679270546498 1.0 0.3415517603885462 3 P12277 1 +Runx3 regulates p14 arf 0.7037037037036967 1.7493073164618838 0.0802379119486098 1.0 0.3425261920948209 3 Q09472,P25440 2 +Cdc6 association with the orc origin complex 0.7016129032257971 1.739614173232332 0.081926788850271 1.0 0.347085377996904 3 Q9UBD5,Q99741 2 +Rho gtpase cycle 0.3252700939199671 1.7347802265777612 0.0827797398336565 1.0 0.347085377996904 154 P30519,Q96N67,P34897,Q8N684,Q86XL3,P49257,Q13017,Q9UNZ2,Q9Y2A7,Q03001,P51572,Q9UQB8,Q16512,Q96CS3,P31948,P12814,P67936,Q96HY6,Q14185,O75323,Q13177,Q14254,Q07065,Q16543,Q96F07,Q92888,Q9NZM3,O15173,Q13576,Q13464,P12277,P28288,P06753,P08670,Q92974,Q9NNW5,P51648,O94887,Q86UP2,Q5VTR2,P20700,Q9P0I2,Q5JTV8,Q9P2R3,Q13505,P63000,Q13813,Q01968 48 +Regulation of plk1 activity at g2 m transition 0.4425802476189 1.7306787858724075 0.0835090709699442 1.0 0.3472122611078282 35 P17252,O95067,Q13409,P23258,P04350,Q99996,Q13561 7 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.699509690416763 1.7298567624716925 0.0836558699665426 1.0 0.3472122611078282 3 P54619 1 +Cytosolic iron sulfur cluster assembly 0.6984812694745327 1.7290904425141806 0.0837929094393272 1.0 0.3472122611078282 8 P18074,Q6FI81,O76071 3 +Signaling by alk in cancer 0.4458086797656412 1.724242976286901 0.0846639887629974 1.0 0.3490901911929339 34 P49589,P19174,P06753,P12270,Q8IWJ2,P62753,P27361,O43815,P35579,P26038,P51608,P67936 12 +Formation of apoptosome 0.7485295234174195 1.7112977366652886 0.0870261639716216 1.0 0.3562648779455219 5 Q9NR28,Q96GX9 2 +Basigin interactions 0.714926304434736 1.7093428732706473 0.0873874560729925 1.0 0.3562648779455219 7 P35613 1 +Netrin 1 signaling 0.6592370946264857 1.6905394570692542 0.0909247962092907 1.0 0.3629286357167451 10 Q14185,P19174,P15311,Q00169,Q16512,P63000 6 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7098582218059031 1.6860432477669327 0.0917874697231058 1.0 0.3646064797480454 7 Q09472,Q9HCE1 2 +Insulin processing 0.6582695946592135 1.6856604325449456 0.0918612220738175 1.0 0.3646064797480454 10 Q9Y4I1,Q8IYI6,Q9UPT5,P51159 4 +Striated muscle contraction 0.741286428119381 1.6797451091705893 0.0930069190632645 1.0 0.3668934767742737 5 P08670,P67936 2 +Ros and rns production in phagocytes 0.6849446719242086 1.664725931137518 0.0959674470718514 1.0 0.3756288163781886 8 Q9Y487,Q93050 2 +Regulation of runx1 expression and activity 0.7357826713899236 1.655725456676041 0.0977774295997853 1.0 0.3805505454855126 5 Q00534 1 +Fasl cd95l signaling 0.6189907435055262 1.6531410631000336 0.0983021578925775 1.0 0.3805505454855126 2 Q14790 1 +Muscle contraction 0.4676935459740114 1.64481781698536 0.1000073867851187 1.0 0.3850420641072829 27 Q05682,P06753,P17252,P08670,Q13555,Q99996,P16615,P67936 8 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.744894807579518 1.6416835057817196 0.1006556116775914 1.0 0.3854373422776061 4 Q00534 1 +Peptide hormone metabolism 0.5835964121894113 1.6346693676858914 0.1021183773205245 1.0 0.3899818031186517 14 Q9Y4I1,P67812,P51159,Q8IYI6,Q9UPT5 5 +Mitochondrial biogenesis 0.4251145767942411 1.6307539561624738 0.1029422464907692 1.0 0.3910145007834863 37 P18859,Q15648,O00411,P00367,P06576,Q00059,Q9NVH1,Q9NX63,P54646,O75964,P56134,P54619,P25705,Q04837,O75431,Q13505 16 +Recruitment of numa to mitotic centrosomes 0.4380056670409623 1.6250026132921391 0.1041620020003841 1.0 0.3945868869344311 33 P17252,Q13409,P23258,P04350,Q99996,Q9UIS9,Q13561 7 +Recruitment of mitotic centrosome proteins and complexes 0.447237013080314 1.6226939194857153 0.1046548518714884 1.0 0.3953938654930835 30 P17252,Q13409,P23258,P04350,Q99996,Q9UIS9,Q13561 7 +Cytochrome p450 arranged by substrate type 0.6761845592133569 1.6212198212374769 0.1049705032825183 1.0 0.3955288563685291 3 Q16850 1 +Trif mediated programmed cell death 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3961471576628874 2 Q14790 1 +Tlr3 mediated ticam1 dependent programmed cell death 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3961471576628874 2 Q14790 1 +Activation of rac1 0.7388706304152926 1.6158789344024542 0.1061204909764352 1.0 0.3961471576628874 4 P63000,Q13177,Q16512 3 +Collagen biosynthesis and modifying enzymes 0.6284229884943572 1.6141459803890426 0.106495765936212 1.0 0.3961471576628874 11 Q32P28,O60568 2 +Maturation of sars cov 2 nucleoprotein 0.7259338424116055 1.6126531695442945 0.1068198800953403 1.0 0.3961471576628874 5 P78362 1 +Activation of ampk downstream of nmdars 0.690668312011323 1.597499834125165 0.1101543346271629 1.0 0.4042807138394318 7 P54619,P04350 2 +Signaling by nodal 0.6675662911819602 1.580900327550275 0.1139008294311267 1.0 0.4116160408853763 3 P27361 1 +Signaling by activin 0.6675662911819602 1.580900327550275 0.1139008294311267 1.0 0.4116160408853763 3 P27361 1 +Ion transport by p type atpases 0.6366294619391593 1.5761287731273144 0.1149961292098278 1.0 0.4134593653269382 10 Q8NB49,P16615,Q9HD20 3 +Cellular responses to stimuli 0.270381557608586 1.5699571081933257 0.116425090179846 1.0 0.414314460135671 341 Q9UJW0,Q09472,Q14997,P30519,P62841,Q9UJX5,Q15648,Q8N1F7,Q13555,Q96FJ2,P55735,P31948,Q13409,P04350,Q92993,Q15024,Q00534,Q9Y5K8,P15927,O43242,P09601,P42345,P62081,P47755,P61254,P46778,P55036,O95070,P53004,Q9H1A4,P50914,Q9Y3B2,Q99543,Q13561,P17096,Q9UJX4,Q9Y5M8,P24941,O00231,P08865,P25398,P12270,P16104,P35244,P84098,P62917,Q9HCE1,P61289,P30043,Q9NWT6,P62899,Q9UJX2,Q9UBS4,P49721,P46782,Q8TCT9,P20700,P61513,P14854,Q02543,P62753,P15880,P27361,P02545,Q96EE3,P43307,P27635,P00390,P20042,Q9BTX1 70 +Suppression of apoptosis 0.7273050929358679 1.566232505873374 0.117294195395031 1.0 0.4144672142571814 4 P27361,P14373 2 +Metabolism of water soluble vitamins and cofactors 0.4074453172449865 1.5622450644169408 0.1182302681307929 1.0 0.4144672142571814 40 Q9H2D1,P43490 2 +Fatty acyl coa biosynthesis 0.5578139756975667 1.551294029213511 0.1208312370594693 1.0 0.4205284186330791 15 Q4G176,P53007 2 +Lipophagy 0.7227490507454615 1.5466398522009703 0.1219501142983858 1.0 0.4233796351440276 4 P54619 1 +Class a 1 rhodopsin like receptors 0.6965516377187126 1.5363890670028215 0.1244429865633423 1.0 0.423911695297961 6 P07602 1 +Peptide ligand binding receptors 0.6965516377187126 1.5363890670028215 0.1244429865633423 1.0 0.423911695297961 6 P07602 1 +Slc mediated transmembrane transport 0.508239589689032 1.5357590051793408 0.1245974975020836 1.0 0.423911695297961 19 P53985,Q9UBX3,Q70HW3,P35613 4 +Negative feedback regulation of mapk pathway 0.7199989014533107 1.5348042288418138 0.1248319237401649 1.0 0.423911695297961 4 P36507 1 +G1 s specific transcription 0.6432610581194261 1.5344201235776789 0.1249263300611382 1.0 0.423911695297961 9 P00374 1 +Trna modification in the mitochondrion 0.6952278775296812 1.5304407610762687 0.1259076660690561 1.0 0.423911695297961 6 O15091,Q9Y606 2 +Ras activation upon ca2 influx through nmda receptor 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4 +Unblocking of nmda receptors glutamate binding and activation 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4 +Long term potentiation 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3628772430519456 1.5245221733312375 0.1273783221882181 1.0 0.427519166869245 62 P18859,Q9P0J0,P51970,O75380,P06576,P14854,O43676,Q9UDW1,O75964,P22695,P56134,Q86Y39,Q9BQ95,O75306 14 +Rhou gtpase cycle 0.5522865799449844 1.51860868443281 0.1288610238662917 1.0 0.4301434560775037 15 Q13177,Q03001,Q13813,Q16512,Q9NNW5,Q9NZM3 6 +Sphingolipid de novo biosynthesis 0.6251542041998068 1.5177656845586678 0.1290734786814307 1.0 0.4301434560775037 10 P51648,Q9Y5P4,Q96G23,Q06136 4 +Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6505376344085935 1.500994651732618 0.133356944886599 1.0 0.4392386086824345 3 Q13951,P17931 2 +Signaling by braf and raf1 fusions 0.4617621242229526 1.4976607090612448 0.1342214250393112 1.0 0.4409678096387038 25 Q9NRY5,P36507,Q13555,P27361,P02545,Q96PU8,Q99996 7 +Cristae formation 0.5020407505912289 1.4948846408972558 0.1349445513874601 1.0 0.4409678096387038 19 P18859,P06576,Q9NVH1,Q9NX63,O75964,P56134,P25705,O75431,Q13505 9 +Diseases of immune system 0.7105689224906236 1.4941735539114291 0.1351302629678406 1.0 0.4409678096387038 4 O15111 1 +Small interfering rna sirna biogenesis 0.6472520908004693 1.4855457530049758 0.137399312850093 1.0 0.4463108713958193 3 O75569,Q15631 2 +Polo like kinase mediated events 0.6827123651693945 1.4741243750794926 0.1404481067275274 1.0 0.454126258137291 6 O95067 1 +Dscam interactions 0.6403234410524405 1.4529383392837634 0.146240874837038 1.0 0.469719797830995 3 P63000 1 +Diseases of signal transduction by growth factor receptors and second messengers 0.3113516105447512 1.4467909342611935 0.1479554866304688 1.0 0.4708583392091273 151 Q09472,Q14997,P49589,P49815,P62191,Q13555,Q14789,Q99996,Q92530,P67936,Q9UNM6,O15111,O43242,P42345,Q13485,Q15008,O43815,Q96PU8,Q16543,P55036,O95429,Q9NWH9,Q9NRY5,Q01082,P19174,Q09161,P06753,P36507,O00231,P12270,Q8IWJ2,P61289,P35579,P49721,Q6WCQ1,P62753,P27361,P02545,Q9UBN7,P26038,P51608,P63000 42 +Switching of origins to a post replicative state 0.3575628964160782 1.431403927343554 0.1523144834845902 1.0 0.479152181790544 59 Q14997,Q9UJX5,P62191,Q92530,P25205,Q9UNM6,O43242,Q16763,P55036,Q9UJX4,Q9H1A4,P24941,O00231,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 20 +Synthesis of pips at the golgi membrane 0.6212482125720251 1.4254029685667724 0.1540407504539525 1.0 0.479152181790544 9 Q99570,P42356,Q9UBF8,Q08AM6,Q10713,Q01968 6 +Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.6944203745212926 1.4244486452830518 0.1543166410496423 1.0 0.479152181790544 4 P16104 1 +Insulin receptor recycling 0.6145747247542139 1.3922672913013134 0.1638414723978778 1.0 0.4989396562461236 9 Q9Y487,Q93050 2 +Cell cycle mitotic 0.2770608379401652 1.3804648601637977 0.1674435618828458 1.0 0.5077204998722342 264 P04183,Q09472,Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,Q9BRT9,P55735,P42695,Q13409,P04350,Q71F23,Q99996,P23258,O95235,O00139,P00374,Q92530,P25205,Q96EA4,Q99986,P28340,Q9BZD4,Q00534,Q9UNM6,O43242,Q15008,O95067,Q13257,P15927,Q14674,Q16763,P55036,Q9NR33,Q9UJX4,P51530,Q9H1A4,Q9Y2S7,Q13561,P24941,O00231,O60763,P12270,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P17252,Q9UIS9,P67870,P49721,P04818,Q08379,Q86XI2,O75122,P30622,P20700,P33992,P27361,P02545,Q96EE3,Q9BSJ2,O75330,O15504,Q9BTX1 72 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5060812834508113 1.372848154378772 0.1697995570306374 1.0 0.5104824980516823 17 Q15293,O43852,Q07065,Q06481,Q02818 5 +Sema4d in semaphorin signaling 0.6197558030906101 1.3515463497238875 0.1765204830202673 1.0 0.5242066143817249 8 P35580,Q13464,O75116,P35579,P63000,Q9NWH9 6 +Signaling by scf kit 0.6063373547513258 1.351327707536435 0.1765904801455775 1.0 0.5242066143817249 9 P17252,P63000 2 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6174641751180484 1.3404735180195049 0.1800914482690023 1.0 0.5323623774144358 8 Q9H1A4,Q9UJX4,Q9UJX2,Q9UJX5 4 +Assembly and cell surface presentation of nmda receptors 0.5754285277118327 1.335384199774338 0.1817506333483969 1.0 0.5350284269193435 11 Q15334,Q13555,P04350,Q92796,Q13557,Q12959 6 +Carboxyterminal post translational modifications of tubulin 0.6514122156587931 1.3328210326553875 0.1825905417953703 1.0 0.5363834419061504 6 P04350 1 +Rhoa gtpase cycle 0.3690574432148314 1.3313716265955386 0.1830667606546907 1.0 0.5366666655707013 47 O15173,Q86UP2,P30519,Q14254,Q13017,P28288,P49257,Q9P0I2,P51572,Q16512,Q96CS3,Q96HY6 12 +Raf independent mapk1 3 activation 0.632114918409947 1.324990380313556 0.1851743419301921 1.0 0.5371552143305452 7 P36507 1 +Apc c cdc20 mediated degradation of cyclin b 0.5873069512709702 1.324298980742962 0.1854037689090546 1.0 0.5371552143305452 10 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4 +Pre notch expression and processing 0.5586295816826774 1.3224140677674987 0.186030306920617 1.0 0.5371552143305452 12 Q09472,Q9HCE1,P16615 3 +Signaling by insulin receptor 0.5190145892807728 1.3209047759320396 0.1865331171097111 1.0 0.5371552143305452 15 Q9Y487,Q93050 2 +Inactivation of cdc42 and rac1 0.6122498980804549 1.3205471726651812 0.1866523971824765 1.0 0.5371552143305452 3 P63000 1 +Interleukin 4 and interleukin 13 signaling 0.5438277824294979 1.3203274998920418 0.1867256978938345 1.0 0.5371552143305452 13 P09601 1 +Defective ripk1 mediated regulated necrosis 0.6120071684587712 1.3194014519433428 0.1870349366246484 1.0 0.5371552143305452 3 Q14790,Q12933 2 +Fcgamma receptor fcgr dependent phagocytosis 0.409624938321452 1.309436650665832 0.1903864833498483 1.0 0.542371171317209 30 Q14185,Q9Y4I1,P19174,P35240,P61160,Q8IV08,Q9Y2A7,P27361,Q9UQB8,Q16512,Q96F07,P59998,P63000 13 +Factors involved in megakaryocyte development and platelet production 0.3584613645068727 1.2920731725854049 0.1963318054518028 1.0 0.5504302402845187 50 Q96N67,P04350,O00139,O95235,Q14185,P52907,P47755,O95140,P33176,P24941,Q9H0B6,Q99661,Q9NRW7,P17252,Q9BW19,Q9NS87,Q9Y496,O60333,P63000 19 +Cell surface interactions at the vascular wall 0.5012167697964549 1.276266438719933 0.2018613497291166 1.0 0.562583998357479 16 P53985,P14174,P35613 3 +Recycling of eif2 gdp 0.599219075063677 1.2522752110298483 0.2104695983754863 1.0 0.5763077301869296 8 P20042,Q13144 2 +Metabolism of steroids 0.3568111266061973 1.2492181052771023 0.2115853116423707 1.0 0.5763077301869296 49 P37268,Q13907,Q15125,Q15126,P04062,Q16850,P38435,Q15800,Q15392 9 +Pyroptosis 0.6424495149321838 1.2444728758956611 0.2133255761222787 1.0 0.5775927654219332 5 P09429 1 +Transferrin endocytosis and recycling 0.5716756747790578 1.2441735036901689 0.2134357132475399 1.0 0.5775927654219332 10 Q9Y487,Q93050 2 +Cellular response to chemical stress 0.3273631940968227 1.2421105945529167 0.2141957601423163 1.0 0.5775927654219332 77 Q14997,P30519,Q8TCT9,P14854,P09601,P55036,P53004 7 +Complex i biogenesis 0.414958675544625 1.230733202417686 0.2184226657219719 1.0 0.5867513814926736 27 Q9P0J0,P51970,O75380,O43676,Q86Y39,Q9BQ95,O75306 7 +Golgi cisternae pericentriolar stack reorganization 0.5549383559961865 1.2270545916478697 0.2198020731440226 1.0 0.587728391827496 11 P27361,Q08379,O95067 3 +Pp2a mediated dephosphorylation of key metabolic factors 0.5890083632019006 1.210877023002842 0.2259425398931591 1.0 0.5989808796792381 3 P30154,P30153 2 +Nrif signals cell death from the nucleus 0.530904747685882 1.1976697352517869 0.2310456159874623 1.0 0.605691011855815 2 Q92542 1 +The phototransduction cascade 0.6021300696715887 1.1849112860865738 0.2360525246020874 1.0 0.6176707727087956 7 P50579,P49354,P53582 3 +Josephin domain dubs 0.5821385902030949 1.1785033285721618 0.2385960061360728 1.0 0.6231721934755469 3 P54725,P55072 2 +Synthesis of pc 0.6371478455174755 1.176597747775196 0.2393560971583528 1.0 0.6240039949903183 4 P35790,P67870 2 +Nuclear envelope ne reassembly 0.3450978975546493 1.173600524647949 0.2405550709720796 1.0 0.6259747979439199 51 Q86XL3,O95067,Q8WUX9,P55735,Q96EE3,Q9BTX1 6 +Regulation of pten localization 0.5216482532099206 1.1497812169256043 0.2502339933504878 1.0 0.6440448681315833 2 P98170 1 +Formation of atp by chemiosmotic coupling 0.5501786648836053 1.134072843311437 0.2567639938716466 1.0 0.657260006051878 10 P18859,P06576,P56134,O75964,P25705 5 +Phosphorylation of the apc c 0.5369475858415117 1.1320212338249205 0.2576255074186853 1.0 0.65827277031212 11 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4 +Fceri mediated mapk activation 0.5604142998410184 1.1229887269039631 0.2614422822438129 1.0 0.6635700409299558 9 P27361,P63000,Q13177,Q16512 4 +Metabolism of vitamins and cofactors 0.3469904488238349 1.122740526778522 0.2615477105902095 1.0 0.6635700409299558 48 Q9H2D1,P43490 2 +Dap12 signaling 0.5699744989149291 1.1212807626759138 0.2621683714759055 1.0 0.6638779729309221 3 P63000 1 +Oncogenic mapk signaling 0.3916225241257266 1.117642474094404 0.2637197207173785 1.0 0.6666117448544827 29 Q9NRY5,P36507,Q13555,P27361,Q96PU8,Q99996 6 +Signaling by leptin 0.5138847417139507 1.1097008790231055 0.2671279439959171 1.0 0.6716223930004108 2 P40763 1 +Synthesis of udp n acetyl glucosamine 0.6197918612328908 1.1017128900640334 0.2705865112511729 1.0 0.6782951712065127 4 Q9UJ70,Q06210 2 +Ngf stimulated transcription 0.6194745200967782 1.1003464010935986 0.271181222182379 1.0 0.6782951712065127 4 Q09472 1 +Cyclin d associated events in g1 0.5435314866538676 1.1001018216959908 0.2712877602209462 1.0 0.6782951712065127 10 Q00534 1 +Signaling by rho gtpases miro gtpases and rhobtb3 0.2663409828281365 1.099151247438243 0.271702099718957 1.0 0.6782951712065127 258 P35580,P30519,P34897,P49257,Q9UQB8,Q16512,Q96CS3,P67936,Q14185,Q15345,O75323,Q96F07,O15173,O43663,P28288,P08670,Q92974,Q9NNW5,Q5VTR2,P30622,P27361,Q9P2R3,Q13505,Q96N67,Q8N684,Q86XL3,Q9UNZ2,Q9Y2A7,Q03001,P55735,Q13409,P12814,Q9BZD4,Q13177,Q07065,Q16543,Q92888,Q9NZM3,Q13464,Q01082,P06753,Q9H0B6,P35579,Q99570,Q9UEY8,Q96EE3,P59998,P35221,P35240,Q13017,P51151,Q96FJ2,Q14344,P31948,P04350,Q71F23,Q68EM7,Q96HY6,Q96EA4,Q13257,O15498,O43237,O95140,P33176,Q96AC1,Q92747,Q99661,Q9H8V3,P17252,P51648,O94887,Q9P0I2,P63000,Q13813,Q01968,P51572,O00139,Q14254,P61160,Q13576,P12277,P16104,Q86UP2,O75122,P20700,Q5JTV8 86 +Smooth muscle contraction 0.5297787447629617 1.0942314390177388 0.2738534861618809 1.0 0.6797471227518219 11 Q05682,P67936,Q16512,P06753 4 +Extracellular matrix organization 0.381789111722336 1.0942168331974045 0.2738598904354945 1.0 0.6797471227518219 31 Q32P28,Q03001,O60568,P35613 4 +Rho gtpases activate iqgaps 0.5166161524920717 1.0932063423067526 0.2743032130077834 1.0 0.6797471227518219 12 P30622,Q13576,P63000,P04350 4 +Kinesins 0.4259304384255919 1.0911545494529078 0.2752048832524214 1.0 0.6797471227518219 22 Q9Y496,P33176,Q9H0B6,Q99661,P04350,O00139,Q9BW19,O95235,Q9NS87 9 +Mitotic g2 g2 m phases 0.3151851366023671 1.0899003442895596 0.2757570449415731 1.0 0.6797471227518219 92 Q09472,Q14997,P24941,O00231,P17252,O95067,P61289,P55036,Q13409,P04350,P49721,Q99996,P23258,Q9UIS9,Q13561,O75330 16 +Synthesis of dna 0.3141045999353485 1.0882068550176904 0.2765037991819166 1.0 0.6797471227518219 86 Q14997,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 27 +Activation of the pre replicative complex 0.4253439065646966 1.0870188510113823 0.2770284787193446 1.0 0.6797471227518219 22 P24941,Q99741,P15927,O43913,P33992,P35244,P09884,Q9NR33,P33991,Q9UBD5,Q14566,P25205 12 +Cytochrome c mediated apoptotic response 0.596473427557717 1.0847575119222252 0.2780290681623418 1.0 0.6797471227518219 6 Q9NR28,Q96GX9 2 +Class i peroxisomal membrane protein import 0.5805242874959078 1.084257959483658 0.2782504397561549 1.0 0.6797471227518219 7 O75381,P40855,P51648 3 +Advanced glycosylation endproduct receptor signaling 0.5640720913504367 1.0826761393121134 0.2789521985259475 1.0 0.6797471227518219 8 P27361,P52907,P09429,P47755 4 +Slc transporter disorders 0.3754875961508347 1.0814439025429594 0.279499701570282 1.0 0.6797471227518219 33 P55735,Q9BTX1,P53985,P35613 4 +Rho gtpases activate ktn1 0.563057757344323 1.0777987183293378 0.2811235916506627 1.0 0.6813510034346251 8 P63000,Q9H0B6 2 +Tnfr1 induced proapoptotic signaling 0.6121900209142539 1.0690127282157058 0.2850639340929441 1.0 0.6858819848164943 4 Q6GQQ9,Q14790,Q12933 3 +Caspase activation via death receptors in the presence of ligand 0.6121900209142521 1.0690127282156974 0.2850639340929479 1.0 0.6858819848164943 4 P49327,Q14790,Q12933 3 +Regulation by c flip 0.6121900209142521 1.0690127282156974 0.2850639340929479 1.0 0.6858819848164943 4 P49327,Q14790,Q12933 3 +Hdms demethylate histones 0.549514876463407 1.0689908195125033 0.2850738061694358 1.0 0.6858819848164943 9 Q8IUF8,Q6NYC1 2 +Activation of atr in response to replication stress 0.4226770146694594 1.0682226188782669 0.2854201040849955 1.0 0.6858819848164943 22 P24941,P15927,P33992,O14757,P35244,Q9UBD5,Q14566,P25205 8 +Aggrephagy 0.4648821924006294 1.0541615994836202 0.2918089377519046 1.0 0.69532214003953 16 Q13409,P08670,Q96FJ2 3 +Base excision repair ap site formation 0.5978737649867162 1.047957043762347 0.2946583985494184 1.0 0.7005186727825565 5 P13051,P16104 2 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5325225984010521 1.0439723470869189 0.2964981837579232 1.0 0.7029394859898416 10 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4 +Recycling pathway of l1 0.4238567618577337 1.0396388515456336 0.2985077195806986 1.0 0.7065182709673822 21 P15311,P35241,P26038,P04350 4 +Processive synthesis on the lagging strand 0.4790569955410275 1.0291701637743558 0.3033997200266927 1.0 0.7130107035244306 14 P51530,P28340,P15927,P35244 4 +Sema4d induced cell migration and growth cone collapse 0.583909324466934 1.0283848924712038 0.3037688121667248 1.0 0.7130107035244306 6 P35579,P35580,O75116,Q13464 4 +Oncogene induced senescence 0.5527219493872664 1.0281899814736963 0.3038604701569345 1.0 0.7130107035244306 8 Q9HCE1,Q00534 2 +Downregulation of smad2 3 smad4 transcriptional activity 0.5525365155122658 1.027301634244326 0.3042784530964131 1.0 0.7130107035244306 8 Q96PU5,Q13485 2 +Apoptotic factor mediated response 0.56753014205984 1.0239971872715106 0.3058366034436395 1.0 0.7154753653408322 7 Q9NR28,Q96GX9 2 +Ncam signaling for neurite out growth 0.5899754676962838 1.0133775941648768 0.3108798373570733 1.0 0.7226100993256723 5 P27361,Q13813 2 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4480085430052516 1.008392166887725 0.3132662318857186 1.0 0.7244602056538797 17 P61758,Q9NQP4,P04350 3 +Purine salvage 0.5789610315700743 1.0062542501067135 0.3142932817828117 1.0 0.7256477241161975 6 P55263 1 +Cyclin a b1 b2 associated events during g2 m transition 0.4989125569991895 0.997178537496551 0.3186778567570907 1.0 0.7321818074760474 12 O95067 1 +M phase 0.2626673076790468 0.9916389230256712 0.3213736949665735 1.0 0.7353873338758135 198 Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,P55735,P42695,Q13409,P04350,Q71F23,Q99996,P23258,O95235,O00139,Q92530,Q96EA4,Q99986,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,Q13257,Q14674,Q16763,P55036,Q9UJX4,Q9H1A4,Q13561,O00231,O60763,P12270,P16104,P61289,P17252,Q9UJX2,Q9UIS9,P67870,P49721,Q08379,Q86XI2,O75122,P30622,P20700,P27361,P02545,Q96EE3,Q9BSJ2,O15504,Q9BTX1 53 +Cd28 dependent vav1 pathway 0.5829215891945903 0.9825922156936217 0.3258081771282388 1.0 0.7432869282138892 5 P63000,Q16512 2 +Respiratory electron transport 0.3256192336412973 0.9764235525126922 0.3288546146601199 1.0 0.7482633985744757 52 Q9P0J0,P51970,O75380,P14854,O43676,Q9UDW1,P22695,Q86Y39,Q9BQ95,O75306 10 +Srp dependent cotranslational protein targeting to membrane 0.3061762526618655 0.9696419478170312 0.3322249961296744 1.0 0.7502144069846669 90 P04843,P62841,P67812,P09132,P61247,P62854,Q9UHB9,P04844,P61254,P62081,P46778,P18621,P50914,Q9Y5M8,P08865,P51571,P84098,P25398,P49458,P62917,P62266,P62899,P62750,P46782,P61513,O76094,Q02543,P62753,P15880,P43307,P46776,P27635 32 +Mitotic g1 phase and g1 s transition 0.3055706360260355 0.969217027748692 0.332436917001258 1.0 0.7502144069846669 78 P04183,P62191,Q92530,P00374,P25205,Q00534,Q9UNM6,O43242,P15927,P55036,Q9NR33,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,P49721,P04818,P33992 21 +Meiotic recombination 0.4684227571566248 0.9678959862811112 0.3330963190807838 1.0 0.7502144069846669 14 P16104,P15927,P35244,P24941 4 +Ire1alpha activates chaperones 0.4029848980425396 0.9672308860013278 0.3334286253265186 1.0 0.7502144069846669 23 P49748,O14773,Q969H8,P02545,P43307,Q13217,O95070,Q9UBS4,Q06210,Q9Y5M8 10 +Hemostasis 0.3000344346502145 0.9632906004376404 0.3354017090303041 1.0 0.7526139607797081 124 Q96N67,P55145,P04350,P35613,O00139,Q8NBX0,O95235,P12814,Q14185,P07602,O43852,P47755,Q12846,Q9UNN8,P14174,P24941,Q9H0B6,P42785,Q06481,P17252,Q9BW19,Q9NS87,Q8NCG7,P27361,P53985,P16615,P63000 27 +Mrna splicing minor pathway 0.3641275736996986 0.962974411611486 0.3355603646788507 1.0 0.7526139607797081 32 P55769,Q9BWJ5,Q09161 3 +Rrna processing in the mitochondrion 0.5674310700301406 0.9548811715732656 0.3396377923754867 1.0 0.7566038943287139 6 O15091 1 +Role of abl in robo slit signaling 0.585082151031 0.9531603860446712 0.3405088141546262 1.0 0.7566038943287139 4 O75122 1 +Response to elevated platelet cytosolic ca2 0.3705027993051055 0.9452162842860956 0.3445484674699868 1.0 0.7594060527254141 29 P07602,P17252,O43852,Q12846,Q06481,Q8NBX0 6 +Signaling by notch3 0.5233282617423585 0.9401287286749124 0.3471515342525053 1.0 0.7594060527254141 9 P67809 1 +Hdr through mmej alt nhej 0.5340278325510283 0.939010787057755 0.3477252060250126 1.0 0.7594060527254141 8 Q9UGN5,P39748,P18887,P49959,Q92878,P09874 6 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.4872847125022886 0.9345179130283086 0.3500368002177119 1.0 0.7620077504867552 12 Q96PU5,Q13485,P27361 3 +Interleukin 21 signaling 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.7620077504867552 2 P40763 1 +Interleukin 9 signaling 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.7620077504867552 2 P40763 1 +Traf6 mediated nf kb activation 0.532149845823838 0.9301008580159452 0.3523188665829888 1.0 0.762607278902535 8 O15111 1 +Parasite infection 0.4022751750175736 0.9251035329805848 0.3549120555038831 1.0 0.7656347090488349 22 Q14185,Q9Y4I1,P61160,Q9Y2A7,P27361,Q96F07,Q9UQB8,P59998,P63000 9 +Acyl chain remodelling of pg 0.4774559570020912 0.92344620331812 0.3557747232030026 1.0 0.7663257376308578 2 Q8NF37 1 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5429625402152868 0.9109997428065304 0.3622955091848099 1.0 0.7681193983510994 7 O15111 1 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3777308138196653 0.9096669490056416 0.3629981795289327 1.0 0.7681193983510994 26 P26038,P14174,Q00169,Q13126 4 +Signaling by mapk mutants 0.4723798148701145 0.8978406261446009 0.3692705222416939 1.0 0.7769089912126841 2 P28482 1 +Interleukin 12 signaling 0.3679619091404618 0.8915721429846665 0.3726223070030241 1.0 0.7811799996962508 28 P26038,P14174,Q00169,Q13126 4 +The citric acid tca cycle and respiratory electron transport 0.3007866507072792 0.8900484300666098 0.3734398818778812 1.0 0.7817341527310314 93 O75390,P18859,Q9P0J0,P51970,O75380,P06576,P14854,O43676,P22695,O75964,Q9UDW1,P21796,P56134,Q86Y39,P35613,P53985,Q9BQ95,O75306 18 +Activation of nmda receptors and postsynaptic events 0.3809573649996067 0.8888134260503245 0.3741033590495761 1.0 0.7819645655873536 25 P54646,Q13555,P54619,P04350,P17252,P63000,Q12959 7 +Ras processing 0.5605085380763504 0.8855506090201081 0.375859736689041 1.0 0.7821354511129306 5 P49354 1 +Pyruvate metabolism 0.4455720475774975 0.8852326249293347 0.3760311796875681 1.0 0.7821354511129306 15 P21796,P35613 2 +Orc1 removal from chromatin 0.3182785974453159 0.8835248641652548 0.3769527545703508 1.0 0.7821354511129306 51 Q14997,Q9UNM6,P24941,O00231,O43242,P33992,P62191,P61289,P55036,P33991,Q9UBD5,Q14566,Q92530,P49721,P25205 15 +Abc family proteins mediated transport 0.3201239601085817 0.8816789234602993 0.3779504617820484 1.0 0.7830557221378802 50 Q14997,Q9UNM6,O00231,P28288,O43242,P62191,Q9NRK6,P61289,P40855,P55036,P49721,P20042,P08183,Q92530 14 +Signaling by vegf 0.361652697878543 0.8736101768078486 0.3823305821561513 1.0 0.790970882264483 29 Q14185,Q13464,Q13177,P19174,P42345,Q9Y2A7,Q9UQB8,Q16512,Q96F07,P17252,P63000 11 +Pi3k akt signaling in cancer 0.4631846452622384 0.869055890089842 0.3848165616314365 1.0 0.7930386655933551 13 P49815,O15111,P42345,Q9NWH9,P63000 5 +Dna strand elongation 0.3565874921343162 0.8672642694027698 0.3857972292207707 1.0 0.7930386655933551 30 P28340,P15927,P33992,P35244,P51530,Q14566,Q9BRT9,Q9Y2S7,P25205 9 +Epha mediated growth cone collapse 0.5160482055881825 0.8541732964910764 0.3930089766734501 1.0 0.8007607110538806 8 P35579,P35580,O75116,Q13464 4 +Signal transduction by l1 0.4942029996072979 0.8508391144854661 0.3948587303440531 1.0 0.8007607110538806 10 P36507,P27361,P63000,Q16512 4 +Copi dependent golgi to er retrograde traffic 0.3207679875214534 0.8499390179523298 0.3953589912992412 1.0 0.8007607110538806 48 Q9Y496,P24390,P49755,P48444,P61923,P33176,Q9H0B6,Q6NUQ1,Q99747,Q9Y3B3,Q99661,P04350,O00139,Q9P2W9,Q9BW19,O95235,Q9NS87 17 +Senescence associated secretory phenotype sasp 0.391401527328337 0.8495715701712359 0.3955633236486968 1.0 0.8007607110538806 22 Q9H1A4,Q9UJX5,P24941,Q00534,P16104,P27361,Q9UJX4,Q9UJX2 8 +Signaling by ntrk2 trkb 0.5517710676059121 0.8481177616338929 0.3963723908322512 1.0 0.8012506269613318 5 P63000 1 +Gpcr ligand binding 0.4919993464396814 0.8398863764551981 0.400972096876194 1.0 0.8050910380504054 10 P07602 1 +Vegfr2 mediated cell proliferation 0.5091172087204333 0.8393897123375104 0.401250654960708 1.0 0.8050910380504054 3 P17252 1 +Role of phospholipids in phagocytosis 0.5091172087204332 0.8393897123375104 0.401250654960708 1.0 0.8050910380504054 3 Q8IV08 1 +Ticam1 traf6 dependent induction of tak1 complex 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1 +Irak2 mediated activation of tak1 complex 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1 +Alpha protein kinase 1 signaling pathway 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1 +Nervous system development 0.2568342933558534 0.833814189679451 0.4043856980221858 1.0 0.8056409847108275 217 P35580,Q14997,P62841,P61247,P62191,P62854,P50570,Q16512,P04350,Q92530,Q12959,Q14185,Q13177,Q9UNM6,P15311,P61160,O43242,Q15008,P61254,P62081,P46778,Q16850,P55036,P18621,P50914,Q00169,Q9NWH9,Q13464,Q01082,P19174,Q09161,A0MZ66,P36507,O00231,P25398,P84098,P08865,P62917,P61289,O43347,P35579,P17252,P62899,P62266,P62750,P67870,P49721,P46782,P35241,O94887,O75122,P46939,P61513,Q02543,P62753,P15880,P27361,P46776,P59998,P27635,P26038,P63000,Q13813 63 +Dna replication 0.2961041679425991 0.8281131026176444 0.4076064498102347 1.0 0.8066497389101704 92 Q14997,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 28 +Initiation of nuclear envelope ne reformation 0.4095955217883195 0.8247491107385568 0.4095140435751347 1.0 0.8092913896107209 18 O95067 1 +Formation of xylulose 5 phosphate 0.502986857825553 0.8116754035973378 0.4169779115069281 1.0 0.814151740173113 3 Q7Z4W1,Q00796 2 +Leishmania infection 0.3256905116682922 0.8058371723450172 0.4203367414182035 1.0 0.8159089772528707 41 Q14185,Q9Y4I1,P19174,P61160,P09601,Q9Y2A7,P27361,Q9UQB8,Q96F07,P59998,P17252,P63000 12 +Interleukin 12 family signaling 0.3473032233220888 0.8050342437945744 0.4207999192330545 1.0 0.8159089772528707 31 P26038,P14174,Q00169,Q13126 4 +Pcna dependent long patch base excision repair 0.3972266677832762 0.8024712336302426 0.4222804219906106 1.0 0.817372926401004 19 P28340,P15927,P35244,Q9NR33,P27695 5 +Cardiac conduction 0.4492444788970781 0.7929293218560315 0.4278190026105177 1.0 0.8266277844762149 13 P17252,Q99996,P16615 3 +Toll like receptor 9 tlr9 cascade 0.3622011261201575 0.7918306290318051 0.4284594404242503 1.0 0.8266277844762149 26 Q15075,P09429,O15111 3 +Mitotic prometaphase 0.2937781037953483 0.7912179483452695 0.428816819547817 1.0 0.8266277844762149 95 Q9BZD4,Q9UQE7,O00139,O75122,P17252,O95067,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P23258,Q99996,Q9UIS9,Q13561 15 +Rnd3 gtpase cycle 0.4193434987674743 0.7803125816845861 0.4352069088781394 1.0 0.8318951482183156 16 Q86UP2,P12277,Q14254,Q13017,Q03001,Q07065,Q9NNW5 7 +Constitutive signaling by aberrant pi3k in cancer 0.5259010059369047 0.7730763843573719 0.4394771763247067 1.0 0.834852240898701 6 O43815,Q9NWH9,P63000 3 +Assembly of the orc complex at the origin of replication 0.523929008439697 0.7646112450161512 0.4445030710714928 1.0 0.8400337537112433 6 Q9UBD5 1 +Cellular response to starvation 0.2910060744060002 0.764299503569985 0.4446887811578273 1.0 0.8400337537112433 90 P62841,P61247,P62854,P55735,Q9UI12,Q9Y5K8,P42345,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q9NXC5,P62753,P15880,Q02543,Q96EE3,P46776,P27635,P20042 29 +Nr1h2 and nr1h3 mediated signaling 0.4855873077310736 0.7582738651732427 0.4482870495771633 1.0 0.8434376589146667 9 Q09472,Q9HCE1 2 +Signaling by gpcr 0.3116906174867415 0.7572862984874779 0.4488783577521793 1.0 0.8434376589146667 48 Q86YR5,Q13464,P07602,Q8NCG7,O75116,Q13555,Q14344,Q92974,P42892,P27361,P62136,Q16512,Q92888,Q9H8V3,P17252,Q13557,Q9NZJ7 17 +L1cam interactions 0.3181009069810578 0.7532564679173995 0.4512958125698025 1.0 0.8446105737233522 43 P35241,Q01082,A0MZ66,P15311,P36507,P50570,P27361,P04350,Q16512,P26038,P63000,Q13813,Q12959 13 +Unwinding of dna 0.4734414647026035 0.748592014711459 0.4541031465158154 1.0 0.8469528012809177 10 Q14566,Q9BRT9,P33992,P25205 4 +Dna replication pre initiation 0.2965596851154723 0.748190065261984 0.45434552255551 1.0 0.8469528012809177 63 Q14997,P62191,Q92530,P25205,Q9UNM6,P15927,O43242,P55036,Q9NR33,P24941,O00231,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,P49721,P33992 19 +Rho gtpases activate nadph oxidases 0.5057591228962429 0.74367521682209 0.4570729862733773 1.0 0.8498777560987437 7 P17252,P27361,P63000 3 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4921848116646035 0.7436015792940519 0.4571175475124169 1.0 0.8498777560987437 8 Q15334,Q13555,P27361,Q13557,Q12959 5 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4383162229079672 0.7340467666975645 0.4629202357818505 1.0 0.8584072088710692 13 O15111 1 +Global genome nucleotide excision repair gg ner 0.3133673764376901 0.7306650900117837 0.4649837438309596 1.0 0.8599764791009764 45 Q07864,Q92759,Q9UNS2,P28340,P15927,Q86WJ1,Q9NR33,P09874,Q13620,P40938,Q9Y2S7,P25490,P35244,P19447,P18074,Q96EZ8,P18887,P35251,Q9UBW8,P54725 20 +Mitochondrial translation 0.2997457031783601 0.7239853518748068 0.4690747279987555 1.0 0.864149401124174 54 Q92665,P46199,P82933,Q9H2W6,Q16540,Q96EY7,Q7Z7H8,Q9Y3D3 8 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4779912570682332 0.7225040653002495 0.4699846268544689 1.0 0.8646982783142769 9 Q7L5D6,O43681,P09601,P51648 4 +Generation of second messenger molecules 0.528570123301029 0.7183622645494454 0.4725339476990431 1.0 0.867130478050322 4 Q13177,Q16512 2 +Sealing of the nuclear envelope ne by escrt iii 0.4551728655282702 0.7095140492885834 0.478005536192386 1.0 0.8694936104762699 11 Q8WUX9 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5104584434472538 0.7073119896839603 0.4793726162902878 1.0 0.8700551962386309 6 Q16850,P46939 2 +Interleukin 20 family signaling 0.4793906810035702 0.7068342363115161 0.4796694960154943 1.0 0.8700551962386309 3 P40763,Q06124 2 +Processing of smdt1 0.4639193902907736 0.7025188120564373 0.4823556740963237 1.0 0.8726870262459737 10 Q9UJZ1,Q10713,Q96TA2 3 +Dual incision in gg ner 0.3550419527029562 0.6987101846651812 0.4847331677864517 1.0 0.8747483602583094 25 P18074,P28340,P15927,P35244,Q86WJ1,Q92759,P19447,Q9NR33,P35251,P09874,Q07864,Q13620,Q9Y2S7 13 +Energy dependent regulation of mtor by lkb1 ampk 0.4940832835979857 0.6925307789806786 0.4886040637606308 1.0 0.880609109813484 7 P54619,P42345,P54646 3 +S phase 0.2864863884280132 0.6878129242122406 0.4915705962756758 1.0 0.8827344814343369 99 Q14997,Q9UQE7,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 28 +Nephrin family interactions 0.492851744161275 0.6871836510838253 0.4919670055029073 1.0 0.8827344814343369 7 Q13813,Q01082,P12814 3 +Linoleic acid la metabolism 0.4293819050462819 0.6866834694795836 0.4922822161148319 1.0 0.8827344814343369 2 O95864 1 +Nucleotide excision repair 0.2924176189903731 0.6809970581372988 0.4958733519120151 1.0 0.8843513492598782 59 P18074,Q09472,P28340,P25490,Q96EZ8,P15927,P35244,Q86WJ1,Q9HCS7,Q9NR33,Q9UBW8,P55199,Q9Y2S7 13 +Vesicle mediated transport 0.2492086542195099 0.6787821363734894 0.4972759140842324 1.0 0.8849507136033002 248 Q10472,Q9UJW0,P24390,Q8WUX9,Q96FJ2,Q14789,P50570,P55735,P54619,P33908,Q13409,P04350,Q14108,O00139,Q8WTV0,Q7Z392,P61160,P54646,Q13561,Q9UKS6,Q9H0B6,Q8IWJ2,Q9UPT5,Q9Y2L5,Q4KMP7,Q9P2W9,Q08379,Q8TBA6,P51159,Q9UJ41,Q9Y3B3,Q9UNF0,Q9UBW8,P59998,P63000,Q13813,Q01968 37 +Recognition and association of dna glycosylase with site containing an affected purine 0.5169570795538736 0.6718613059103327 0.5016719957770885 1.0 0.8905308166244047 4 P16104 1 +Base excision repair 0.330571704735991 0.6686325329638514 0.5037299144393803 1.0 0.8930619436673078 31 P28340,P13051,P15927,P16104,P35244,Q9NR33,P27695 7 +Met activates rap1 and rac1 0.5085184715795039 0.6675743264682059 0.5044053503621702 1.0 0.8931387970698577 5 Q9NWH9,P63000 2 +Apc cdc20 mediated degradation of nek2a 0.445719422072912 0.6628060723318472 0.5074547640762652 1.0 0.8951730107862207 11 Q9H1A4,Q9UJX5,Q16763,Q9UJX4,Q9UJX2 5 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.445719422072912 0.6628060723318472 0.5074547640762652 1.0 0.8951730107862207 11 Q9H1A4,Q9UJX5,Q16763,Q9UJX4,Q9UJX2 5 +Interactions of vpr with host cellular proteins 0.3218673625397498 0.6594797768842792 0.5095877281813976 1.0 0.8978147879305672 35 P55735,Q9BTX1,P17096,P12235 4 +Synaptic adhesion like molecules 0.4861895323179202 0.6584278674682262 0.5102632333673434 1.0 0.8978853658132704 7 Q12959,Q15334,O75955,Q14254 4 +Platelet activation signaling and aggregation 0.2953719254832497 0.6534334615662846 0.5134768725711707 1.0 0.9003606690695268 52 P07602,P17252,O43852,Q8NCG7,Q06481,Q8NBX0,P63000 7 +Cd209 dc sign signaling 0.4849874340787517 0.6532710878340039 0.5135815281458165 1.0 0.9003606690695268 7 P17252,Q09472,Q16512 3 +Regulation of hmox1 expression and activity 0.303326077447476 0.6456810666672699 0.5184859246678708 1.0 0.9066661430164432 46 Q14997,Q9UNM6,O00231,P67870,Q8TCT9,O43242,P62191,P09601,P61289,P55036,P49721,Q92530 12 +Mapk6 mapk4 signaling 0.2955448269100328 0.6447283170932487 0.5191032623498248 1.0 0.9066661430164432 51 Q16181,Q14997,Q9UNM6,Q13177,O00231,O43242,P62191,Q9HCE1,P61289,P55036,Q16512,P49721,P17252,P63000,Q92530 15 +Visual phototransduction 0.4514223160779367 0.6430172121159914 0.52021293144097 1.0 0.9071597626428552 10 P50579,P49354,P53582 3 +Phosphorylation of emi1 0.4644563918757307 0.6423131170680662 0.5206698991531178 1.0 0.9071597626428552 3 P06493,P53350 2 +Nuclear pore complex npc disassembly 0.3254811695065014 0.6406626949711794 0.5217418565126173 1.0 0.907750332837131 32 P12270,O95067,P55735,Q96EE3,Q9BTX1 5 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.5088348799157193 0.6398137136639652 0.5222937159211518 1.0 0.907750332837131 4 O94887 1 +Cdc42 gtpase cycle 0.3276967218728149 0.6343627567369956 0.5258441091934851 1.0 0.9101349276459704 30 Q13576,Q86UP2,Q9Y5S2,Q96N67,Q13177,Q13017,P11274,O15498,Q14344,Q9UQB8,Q16512,Q9H8V3,P63167,Q68EM7,Q07960 15 +Mitotic prophase 0.2870605379989706 0.6342382844572864 0.5259253260736958 1.0 0.9101349276459704 62 Q08379,Q86XI2,P20700,O60763,O95067,P12270,P16104,Q8N1F7,P27361,P55735,P02545,Q96EE3,P42695,P17252,O15504,Q9BTX1 16 +Hcmv early events 0.3007648766171402 0.6337527322713179 0.5262422051569411 1.0 0.9101349276459704 47 P12270,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P83916,Q9BTX1 8 +Caspase mediated cleavage of cytoskeletal proteins 0.4670997504386013 0.6308635644194333 0.5281297371680278 1.0 0.9108165626802156 8 P08670 1 +Synthesis of pips at the late endosome membrane 0.5058359792721369 0.6280883640118754 0.5299460552541064 1.0 0.9109656643236648 4 Q99570,Q08AM6 2 +Traf6 mediated induction of tak1 complex within tlr4 complex 0.460274790919937 0.6245495866025543 0.5322667158940328 1.0 0.9121104260779276 3 Q15750,Q6SZW1 2 +Trafficking of ampa receptors 0.4273321245859249 0.6217928996369695 0.5340780557774008 1.0 0.9121276210572742 12 Q15334,Q13555,P17252,Q13557,Q12959 5 +Termination of translesion dna synthesis 0.3682471774003555 0.6191416082218253 0.5358230748900215 1.0 0.9121903672525304 19 P28340,P15927,P35244,Q9UBZ9,Q9NR33 5 +Translation of replicase and assembly of the replication transcription complex 0.5002081123322807 0.6062497542101688 0.5443489183940491 1.0 0.9201490100615464 4 Q99570,Q8WUX9 2 +Rnd1 gtpase cycle 0.4139627630772918 0.6061649610616873 0.5444052175594145 1.0 0.9201490100615464 13 Q14254,Q13017,Q03001,P31948,P51648 5 +Rho gtpases activate wasps and waves 0.3805681723438792 0.5996697573644033 0.5487263472447204 1.0 0.9247288925165318 17 P61160,P27361,Q96F07,Q9UQB8,P59998,P63000 6 +Interconversion of nucleotide di and triphosphates 0.3613733387224164 0.5970652180678642 0.5504638388149121 1.0 0.924857793395328 20 P00390,P04818,Q9H773,Q9Y3D8 4 +Signaling by alk 0.4828079660477985 0.5931383764452967 0.5530885493096376 1.0 0.9259645973631728 6 Q09472 1 +Membrane trafficking 0.245329958914898 0.5859096285033754 0.5579362465567961 1.0 0.930772038234655 242 Q10472,Q9UJW0,P24390,Q8WUX9,Q96FJ2,Q14789,P50570,P55735,P54619,P33908,Q13409,P04350,Q14108,O00139,Q7Z392,P61160,P54646,Q13561,Q9UKS6,Q9H0B6,Q8IWJ2,Q9UPT5,Q9Y2L5,Q4KMP7,Q9P2W9,Q08379,Q8TBA6,P51159,Q9UJ41,Q9Y3B3,Q9UNF0,Q9UBW8,P59998,P63000,Q13813,Q01968 36 +Formation of incision complex in gg ner 0.3775486727525456 0.5822990404656379 0.5603652717046383 1.0 0.9326220599748576 17 P18074,P15927,P35244,Q86WJ1,P19447,P54725 6 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4468339307048816 0.568465458142911 0.5697189539118579 1.0 0.9437431206066296 3 P49916,P18887 2 +Resolution of abasic sites ap sites 0.3249094452064286 0.5605788347052757 0.5750846834257537 1.0 0.9480547969224744 28 Q9UGN5,P28340,P13051,P15927,P35244,P18887,P18858,P27695,P35251,Q9NR33,P09874,Q07864,P40938,P29372,Q9Y2S7 15 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3480790951695964 0.5589273355854102 0.5762113127138968 1.0 0.9480547969224744 22 P28340,P15927,P35244,Q9UBZ9,Q9NR33,Q8TAT6 6 +Regulation of mecp2 expression and activity 0.3945222867376484 0.5587277501916982 0.5763475375487654 1.0 0.9480547969224744 14 P17252,Q9HCE1,Q13555 3 +Glycogen synthesis 0.4739241474642853 0.5576426473769681 0.5770884283718067 1.0 0.9481697084760032 6 P46976,Q16851,Q96G03 3 +Telomere c strand lagging strand synthesis 0.343496637800348 0.5550577467415713 0.5788551625629186 1.0 0.9499678800248594 23 P28340,P15927,P54132,P35244,P51530,Q9Y2S7 6 +Oxidative stress induced senescence 0.3626140280061131 0.5390874138250629 0.589826539722762 1.0 0.9612743951883076 18 Q9HCE1,P16104,Q00534 3 +Nuclear envelope breakdown 0.2950242691739609 0.5377497698737224 0.5907498140514644 1.0 0.9616699161920728 43 P20700,P12270,O95067,P55735,Q96EE3,P17252,Q9BTX1 7 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.3397568244145715 0.5306041706058581 0.5956931049805463 1.0 0.9637374603087792 23 O15111,P09429,Q3LXA3 3 +Rac1 gtpase cycle 0.294126257023356 0.5296425422903698 0.596359792362084 1.0 0.9637374603087792 43 Q14185,Q13576,Q86UP2,O94887,Q96N67,Q13177,Q13017,Q96AC1,Q9Y2A7,Q14344,O15498,Q9UQB8,Q16512,Q96F07,Q9H8V3,Q68EM7,P63000 17 +Toll like receptor cascades 0.3098031766921977 0.5287207672320033 0.5969991687020111 1.0 0.9637374603087792 33 Q15075,P09429,Q9BQ95,O15111 4 +Signaling by interleukins 0.2731631499722867 0.5280582335326901 0.5974589184547048 1.0 0.9637374603087792 117 P14174,Q14997,O15111,P08670,P09429,P09601,P55036,Q13126,P26038,Q00169,P49721 11 +Meiosis 0.325776763544861 0.5262447571745904 0.5987181603152867 1.0 0.9637374603087792 26 Q9UQE7,P24941,P20700,P15927,P16104,P35244,P54132,P49959,P02545 9 +Reproduction 0.325776763544861 0.5262447571745904 0.5987181603152867 1.0 0.9637374603087792 26 Q9UQE7,P24941,P20700,P15927,P16104,P35244,P54132,P49959,P02545 9 +Transcriptional regulation of granulopoiesis 0.4345511090680345 0.5261322059316947 0.5987963533128455 1.0 0.9637374603087792 9 Q09472,P24941 2 +Hiv transcription elongation 0.3302176792818174 0.5243720864348379 0.6000197673578143 1.0 0.9637374603087792 25 P18074,P55199,Q14241,Q09161 4 +Myd88 independent tlr4 cascade 0.3198553577275492 0.5236280477999857 0.6005372694445663 1.0 0.9637374603087792 28 O15111 1 +Estrogen dependent gene expression 0.3048865191697579 0.5186004009189757 0.6040394294427831 1.0 0.96659990238126 35 Q09472,Q9UQE7,P25490,P16104,Q99873,Q9HCE1,Q92993 7 +Toll like receptor tlr1 tlr2 cascade 0.3332394609759049 0.5150392504353413 0.606525592438012 1.0 0.968516601815948 24 O15111,P09429 2 +Adaptive immune system 0.2382493065001929 0.5125155844641303 0.6082902160728114 1.0 0.9686217389035684 192 Q9UJW0,Q14997,O95376,Q9UJX5,Q93034,Q96FJ2,P51572,P50570,P55735,Q16512,Q13409,P04350,O00139,Q8NEZ5,Q15345,O15111,O43242,P42345,P47755,Q12846,P55036,Q9UJX4,Q9H1A4,Q13561,O00231,Q8TDB6,O94874,Q96PU5,Q9H0B6,P61289,P17252,Q9UJX2,Q9GZZ9,P49721,P09429,P63000 36 +Disorders of transmembrane transporters 0.2718321734026235 0.508696015687872 0.6109653156021246 1.0 0.9710843542697436 74 Q14997,P55735,P55036,P35613,P53985,P49721,Q9BTX1 7 +Nrage signals death through jnk 0.4380084952951883 0.5063888427347177 0.6125837055071246 1.0 0.972156587550862 8 Q14344,Q92974,P63000,Q92888 4 +Response of eif2ak4 gcn2 to amino acid deficiency 0.2691226222483104 0.5057731102985917 0.6130159373728366 1.0 0.972156587550862 78 P39023,P62841,P61247,P62854,P61254,P62081,P46778,P46777,P18621,P50914,P83731,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635,P20042,P62913 27 +Activation of gene expression by srebf srebp 0.3476643609004337 0.4951251370260947 0.6205117909754985 1.0 0.9763821940878864 19 Q15126,Q16850,Q13907,P37268 4 +Intraflagellar transport 0.401267723000243 0.4951170660341897 0.6205174878208932 1.0 0.9763821940878864 12 Q9Y496,Q9BVA1,Q96FJ2,P04350,P63167 5 +Protein folding 0.2970537429267526 0.4917955258094315 0.6228638997908322 1.0 0.978337168465986 38 Q9NQP4,P04062,P61758,P04350 4 +Runx2 regulates bone development 0.4339380363457762 0.4896381316713977 0.6243899885151554 1.0 0.978337168465986 8 Q13485,Q9UBN7,P27361 3 +Gluconeogenesis 0.3420111847406037 0.4789351751410836 0.6319847461694954 1.0 0.9835417564538382 20 Q9UBX3 1 +Cargo trafficking to the periciliary membrane 0.3657763832743003 0.4782708481465038 0.6324574422763427 1.0 0.9835417564538382 16 O75695,Q10713 2 +Rnd2 gtpase cycle 0.3722006693500756 0.4773769124887494 0.6330937514661799 1.0 0.9835417564538382 15 Q86UP2,Q13017,Q03001,Q07065,P51648 5 +Transport of the slbp dependant mature mrna 0.3059635878585289 0.4769181865725224 0.6334203810141492 1.0 0.9835417564538382 31 Q09161,P12270,P55735,Q96EE3,Q9BTX1 5 +Mastl facilitates mitotic progression 0.4645951598446463 0.4738677168687756 0.6355942416853793 1.0 0.9858338787063018 4 P06493,P30153,P30154 3 +Uptake and function of diphtheria toxin 0.4631012847326029 0.4685644371917662 0.6393810020792814 1.0 0.98779625765681 4 P08238,Q16881,P13639 3 +Transcription coupled nucleotide excision repair tc ner 0.2832311154159438 0.4674845408087923 0.64015324990948 1.0 0.98779625765681 47 P18074,Q09472,P28340,P15927,P35244,Q9HCS7,Q9NR33,Q9UBW8,P55199 9 +Amino acids regulate mtorc1 0.3942850985045535 0.4626005870067999 0.6436506878115411 1.0 0.9909896311319584 12 Q9Y5K8,P42345,Q9NXC5,P55735,Q96EE3 5 +Signaling by receptor tyrosine kinases 0.2676087505972497 0.4546174235421588 0.6493844976186611 1.0 0.9930522674623032 118 Q09472,Q96N67,Q93034,Q93050,Q9Y2A7,P50570,Q9UQB8,Q16512,Q9Y487,Q14185,Q13177,Q13043,Q9Y5K8,P42345,Q16543,Q96F07,Q9NWH9,Q13464,P19174,Q09161,P36507,O14757,P17252,P20338,P16949,P27361,Q01085,P31483,P63000 29 +Apoptotic execution phase 0.2991363126462978 0.4460795881930732 0.6555397566372485 1.0 0.9981440475521898 33 P49354,P26583,P08670,P09429,P51572,O00429,Q13813 7 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.4437425903006547 0.4424609395136221 0.6581556896824918 1.0 0.9999720317433988 6 Q13485,P27361 2 +Heme signaling 0.405090991941081 0.4353805980047172 0.6632861910281431 1.0 1.0 10 Q09472,P09601 2 +Translation 0.237777265024097 0.4347983352206787 0.6637088134153526 1.0 1.0 220 Q92665,P04843,Q9Y285,P49589,P62841,P67812,P23381,P09132,Q9NR50,Q9H2W6,P60228,Q9UHB9,P61247,Q96EY7,P62854,Q9P015,P46199,P04844,Q9HA77,P61254,Q16540,P62081,P46778,Q5T160,Q13144,Q96RP9,P50914,Q9Y5M8,Q13084,P82933,P08865,P51571,P84098,P25398,P49458,P62917,Q96A35,P62899,Q9BW92,P62266,P62750,P46782,P29692,P61513,P55010,O76094,Q02543,P62753,P15880,Q7Z7H8,P43307,P46776,P27635,Q92552,P20042,Q9Y3D3 56 +Cell death signalling via nrage nrif and nade 0.396205906124071 0.4324187655383319 0.6654370817315434 1.0 1.0 11 Q14344,Q92974,P63000,Q92888 4 +Eukaryotic translation elongation 0.2628894973147282 0.4314469131662999 0.6661434449216439 1.0 1.0 78 P62841,P61247,P62854,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P29692,P61513,Q02543,P62753,P15880,P46776,P27635 23 +Erks are inactivated 0.4173817248802894 0.4234937359966114 0.6719350678280525 1.0 1.0 8 Q14738,P27361,P30154,P30153,P28482,Q13164 6 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3202641942105626 0.4076571326375633 0.6835254132503235 1.0 1.0 23 P28340,P15927,P35244,Q9NR33,P27695 5 +Metalloprotease dubs 0.4232836023881312 0.4056172172028023 0.6850238763162 1.0 1.0 7 O95630 1 +Mitotic metaphase and anaphase 0.2530673310311961 0.4046953984609031 0.6857014250031324 1.0 1.0 145 Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,P55735,Q13409,P04350,Q71F23,O00139,Q92530,Q96EA4,Q99986,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,Q13257,Q14674,O43237,Q16763,P55036,Q9UJX4,Q9H1A4,O00231,Q96FZ7,P61289,Q9UJX2,P49721,O75122,P30622,P20700,P02545,Q96EE3,Q9BTX1 39 +Signaling by flt3 fusion proteins 0.4366640492040239 0.3966702095607786 0.6916106710313192 1.0 1.0 5 Q14789,Q01082 2 +Intra golgi traffic 0.387650954977581 0.3957704939856022 0.692274345665844 1.0 1.0 11 Q8TBA6,P83436,O15498,P33908,Q99747 5 +Resolution of sister chromatid cohesion 0.2639546506498998 0.3950349587440576 0.6928170884014817 1.0 1.0 68 Q9BZD4,Q9UQE7,O95067,Q96FJ2,P55735,Q96EE3,P04350,Q13409,O00139 9 +Asparagine n linked glycosylation 0.2627498823213158 0.3890403113128485 0.69724632659001 1.0 1.0 118 Q9UJW0,P24390,P04843,P48444,P49257,Q9NR45,P83436,P62191,Q96FJ2,Q14789,Q9Y5P6,P55735,Q13630,P33908,Q13409,P04350,Q2TAA5,P04844,P52907,P61923,P47755,O15498,O43237,Q9H6U8,Q99747,Q06210,Q13561,Q01082,O60763,Q9Y673,Q08379,Q9Y3B3,P49755,Q13813 34 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.271851316605722 0.3859369827082109 0.6995433402243842 1.0 1.0 49 Q14997,Q9UJX5,Q9UNM6,O00231,O43242,Q9UJX4,P62191,P61289,Q16763,P55036,Q9H1A4,P49721,Q9UJX2,Q92530 14 +Hcmv infection 0.264427964534352 0.3830031329198566 0.7017174411478893 1.0 1.0 56 P12270,Q8N1F7,Q8WUX9,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P83916,Q9BTX1 10 +Tnfr2 non canonical nf kb pathway 0.2772783147017577 0.382796174335711 0.7018708982817996 1.0 1.0 43 Q14997,Q9UNM6,O00231,O15111,O43242,P62191,P61289,P55036,P49721,Q92530 10 +Cd28 co stimulation 0.3987332040664378 0.3790447598912216 0.7046546258988702 1.0 1.0 9 P42345,P63000,Q16512 3 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3973971417741562 0.373895197630672 0.7084822894941043 1.0 1.0 9 Q99873 1 +The role of gtse1 in g2 m progression after g2 checkpoint 0.2677237253196257 0.372736736717801 0.7093443916702324 1.0 1.0 51 Q14997,O00231,O95067,P61289,P55036,P04350,P49721 7 +Interleukin 1 signaling 0.2684198884034824 0.3665848962425198 0.713928676108202 1.0 1.0 50 P09429,O15111,Q14997,P55036 4 +Selenoamino acid metabolism 0.2597962549240433 0.3627430795785168 0.7167968155643336 1.0 1.0 91 P39023,P62841,P61247,P62854,P57772,P61254,P62081,P46778,P46777,P62851,P18621,P50914,P83731,P49591,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635,P00390,Q12904,P62913 31 +Apoptosis 0.2599180011091141 0.3579951302620779 0.7203469578605559 1.0 1.0 93 P49354,Q9NR28,Q14997,O00231,P26583,P08670,P09429,O60313,Q96FJ2,Q96GX9,P51572,O00429,Q13813,P55036,P61289,P49721 16 +Interleukin 1 family signaling 0.2644625909940585 0.3567800403814798 0.7212564796719958 1.0 1.0 53 P09429,O15111,Q14997,P55036 4 +Trna processing 0.2605416858533214 0.3541154306014877 0.7232523784525116 1.0 1.0 63 Q2VPK5,O15091,O60294,Q969Y2,P12270,Q9Y606,Q8N1F7,Q52LJ0,P55735,Q96EE3,Q96FX7,Q9BTX1 12 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.3769970884463838 0.3517642736546714 0.7250150537333975 1.0 1.0 11 P38435,Q9BU89,O60725 3 +Ret signaling 0.4079607902049904 0.3507890813571071 0.7257465891534132 1.0 1.0 7 P17252 1 +Trna modification in the nucleus and cytosol 0.321532059540156 0.3487487210823996 0.7272779637336091 1.0 1.0 19 Q2VPK5,Q9Y606,Q96FX7,O60294 4 +Transcriptional activation of mitochondrial biogenesis 0.3397397276924222 0.3465602626502587 0.7289217035683917 1.0 1.0 16 Q00059,P00367,Q15648,P06576,Q04837 5 +Depolymerisation of the nuclear lamina 0.3819565958431811 0.3420431127375589 0.7323184475372173 1.0 1.0 10 P20700,P17252 2 +Lagging strand synthesis 0.3176040983848929 0.3403862641326241 0.7335656614348824 1.0 1.0 20 P51530,P28340,P15927,P35244 4 +Signaling by erbb2 0.3576258072888681 0.3379314527213639 0.7354148445822108 1.0 1.0 13 P17252,Q93034,Q16543 3 +Apoptotic cleavage of cellular proteins 0.3113508790954259 0.3361620181350744 0.7367486930298439 1.0 1.0 22 P49354,P20700,P08670,P51572,P02545,Q13813 6 +Apc c mediated degradation of cell cycle proteins 0.2587676748475797 0.3285728729741728 0.7424785548270323 1.0 1.0 58 Q14997,Q9UJX5,Q9UNM6,P24941,O00231,Q15008,O43242,P62191,Q9UJX4,P61289,Q16763,P55036,Q9H1A4,P49721,Q9UJX2,Q92530 16 +Mitotic spindle checkpoint 0.2573295835711344 0.3153649023864645 0.7524846120263862 1.0 1.0 59 Q9BZD4,Q9H1A4,O75122,Q9UJX5,O00139,P30622,Q9UJX4,Q13257,Q96FJ2,O43237,P55735,Q16763,Q99661,Q96EE3,Q13409,Q71F23,Q9UJX2,Q96EA4 18 +Signaling by ptk6 0.3674328552015505 0.3139380957448257 0.7535680557675577 1.0 1.0 11 Q14185,P63000,P24941 3 +Nuclear events stimulated by alk signaling in cancer 0.3587220107220732 0.3089638488356848 0.757349026735348 1.0 1.0 12 P27361,P51608,P62753 3 +Fc epsilon receptor fceri signaling 0.2557463061702739 0.3001178206484024 0.7640872864911572 1.0 1.0 57 Q14997,Q9UNM6,Q13177,P19174,O15111,O43242,O00231,P62191,P27361,P61289,P55036,Q16512,P49721,P63000,Q92530 15 +Translesion synthesis by polk 0.3606077944491194 0.2879894692050561 0.7733547997022769 1.0 1.0 11 P15927,Q9UBZ9 2 +Cell cycle checkpoints 0.2435641102482293 0.2844437347155683 0.7760703470205526 1.0 1.0 149 Q14997,Q9UJX5,P62191,Q96FJ2,P55735,P49959,Q13409,Q71F23,O00139,Q92993,Q92530,P25205,Q96EA4,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,P15927,Q13257,Q16763,P55036,Q9UJX4,P51530,Q9H1A4,P24941,O00231,O14757,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,Q92547,O75122,P30622,P33992,P54132,Q96EE3 42 +Runx2 regulates genes involved in cell migration 0.3320394147506658 0.2839149356905969 0.7764755702641706 1.0 1.0 2 Q13951 1 +Nonsense mediated decay nmd 0.2514642030301371 0.2811348629399435 0.7786069622661396 1.0 1.0 87 P62841,P61254,P62081,P46778,P50914,Q09161,P08865,P25398,P84098,P62917,Q9UPR3,P62899,P46782,Q9NPI6,P61513,Q02543,P62753,P15880,P27635 19 +Processing of intronless pre mrnas 0.3309347846110729 0.2810880935313983 0.7786428331575115 1.0 1.0 15 Q86U42,Q09161 2 +Ephrin signaling 0.4038950022556592 0.2792413458947306 0.7800596156339779 1.0 1.0 4 P63000,Q16512 2 +Gap filling dna repair synthesis and ligation in gg ner 0.3074616669635664 0.2766308006714174 0.7820636117643285 1.0 1.0 19 P28340,Q9NR33,P15927,P35244 4 +C type lectin receptors clrs 0.2526263588816513 0.2714698108059212 0.7860297156798102 1.0 1.0 57 Q09472,Q14997,Q9UNM6,Q13177,O00231,O15111,O43242,P62191,P61289,P55036,Q16512,P49721,P17252,Q92530 14 +Tcr signaling 0.2565776840610048 0.2635907877558577 0.7920952578587372 1.0 1.0 50 Q14997,Q9UNM6,Q13177,P19174,O15111,O43242,O00231,P62191,P61289,P55036,Q16512,P49721,Q92530 13 +Mrna capping 0.3392804152716295 0.2626295449940988 0.7928361255999388 1.0 1.0 13 Q09161 1 +G2 m checkpoints 0.2501592584612757 0.2586304018095037 0.7959204238783189 1.0 1.0 89 Q14997,P24941,O00231,P15927,P33992,O95067,O14757,P16104,P35244,P61289,P55036,P51530,Q14566,Q92993,P49721,Q9UBD5 16 +Transmission across chemical synapses 0.26043779551314 0.2574935018313508 0.7967978310228265 1.0 1.0 45 O14795,P21964,Q13555,P54646,P54619,P04350,P17252,P63000,Q12959 9 +Beta oxidation of pristanoyl coa 0.3912167126952477 0.2555372261457065 0.7983081954099183 1.0 1.0 5 P51659,O15254 2 +Ephb mediated forward signaling 0.3288903750961234 0.2518346658287653 0.8011688611992436 1.0 1.0 14 Q13464,P61160,Q92747,P59998,Q16512,P63000 6 +Rna polymerase ii transcribes snrna genes 0.2711257138198152 0.247458398340769 0.8045534837475614 1.0 1.0 33 Q96HW7,Q09161,Q9NV88,Q9UL03,Q9NVM9,P55199,Q68E01,Q9NQG5 8 +Dectin 1 mediated noncanonical nf kb signaling 0.2602154332926498 0.2468544129109892 0.8050208978358271 1.0 1.0 43 Q14997,Q9UNM6,O00231,O15111,O43242,P62191,P61289,P55036,P49721,Q92530 10 +Runx2 regulates osteoblast differentiation 0.3834786506430224 0.2456890144925777 0.8059229767581799 1.0 1.0 6 P27361,Q9UBN7 2 +Post translational modification synthesis of gpi anchored proteins 0.3905383881056511 0.2430938542969377 0.8079326920054906 1.0 1.0 4 Q92643 1 +Rhobtb3 atpase cycle 0.386231251659214 0.2419073287312259 0.8088519712623101 1.0 1.0 5 P51151,Q15345 2 +G alpha i signalling events 0.2769999179434779 0.2386943274036011 0.8113426157102053 1.0 1.0 28 P07602,P17252,Q86YR5,Q13555 4 +Sumoylation of intracellular receptors 0.3527479091995121 0.2382057688374602 0.8117215030025933 1.0 1.0 3 O75925,Q8N2W9 2 +Dna damage recognition in gg ner 0.2993896880589029 0.2377810385434942 0.8120509259815043 1.0 1.0 19 Q96EZ8,Q9UBW8 2 +Transcription of the hiv genome 0.2711450803551489 0.2357526086039182 0.8136246444750319 1.0 1.0 31 P18074,P55199,Q14241,Q09161 4 +Ion homeostasis 0.3391385978006787 0.2346815112234066 0.8144559389221206 1.0 1.0 12 P17252,P16615 2 +Mapk family signaling cascades 0.2478970728075309 0.2336729634879905 0.8152388787206752 1.0 1.0 89 Q12959,Q16181,P49354,Q14997,O00231,P36507,Q13555,Q9HCE1,Q13813,P55036,P61289,Q16512,P17252,Q9NWH9,P63000,P49721,O60725 17 +Formation of tc ner pre incision complex 0.2789095366362167 0.2281450946967408 0.8195334438636657 1.0 1.0 26 P18074,Q9HCS7,Q9UBW8 3 +Triglyceride catabolism 0.3687301477709754 0.2266600068732339 0.8206881276299671 1.0 1.0 7 P17252 1 +Triglyceride metabolism 0.3687301477709754 0.2266600068732339 0.8206881276299671 1.0 1.0 7 P17252 1 +Transport of mature mrnas derived from intronless transcripts 0.2629451583471566 0.222488429062671 0.8239336798301737 1.0 1.0 37 P55735,Q9BTX1,Q09161 3 +Late endosomal microautophagy 0.3477997739753274 0.221253807431853 0.8248948149675726 1.0 1.0 10 P08670 1 +Runx3 regulates cdkn1a transcription 0.3114362496267482 0.220566751033028 0.8254297922782905 1.0 1.0 2 Q13485 1 +Regulation of tp53 activity through phosphorylation 0.2644892438725966 0.2202708286965271 0.8256602375648217 1.0 1.0 35 P24941,P15927,O14757,P54646,P35244,P54619,P51530,Q92993 8 +Signaling by fgfr 0.2893177656840076 0.2195798531488166 0.8261983833431858 1.0 1.0 22 P52597,P19174,Q09161,P35269,P27361,P30876,Q01085,P31483,P52272 9 +Signaling by fgfr2 0.2893177656840076 0.2195798531488166 0.8261983833431858 1.0 1.0 22 P52597,P19174,Q09161,P35269,P27361,P30876,Q01085,P31483,P52272 9 +Loss of function of mecp2 in rett syndrome 0.3661433665817226 0.219391063678451 0.8263454306269771 1.0 1.0 7 P17252 1 +Dna damage bypass 0.2771675449239947 0.2184923822698496 0.8270454930198503 1.0 1.0 26 P28340,P15927,P35244,Q9UBZ9,Q9NR33,Q8TAT6 6 +Cellular senescence 0.2528755742115428 0.2172194053852987 0.8280373624025477 1.0 1.0 48 Q9UJX5,Q00534,P24941,P20700,Q9UJX4,P16104,Q9HCE1,Q9H1A4,Q9UJX2,Q92993,P17096 11 +G alpha 12 13 signalling events 0.3392093636719466 0.2127917128832098 0.8314894278816567 1.0 1.0 11 Q13464,Q14344,Q92974,Q92888,Q9H8V3 5 +Programmed cell death 0.2490741450645207 0.2093054007938428 0.8342098359288197 1.0 1.0 105 P49354,Q9NR28,Q14997,O00231,Q14254,P26583,P08670,P09429,Q8WUX9,Q96FJ2,O60313,Q96GX9,P51572,O00429,Q13813,P55036,P61289,P49721 18 +Dna damage telomere stress induced senescence 0.2930426726268738 0.208645111491411 0.834725291635706 1.0 1.0 19 P16104,P24941,Q92993,P17096 4 +G alpha q signalling events 0.3235930070374887 0.2043032393519931 0.8381165387240768 1.0 1.0 13 P17252,Q8NCG7 2 +Neurotransmitter receptors and postsynaptic signal transmission 0.258896435846256 0.2028550272533302 0.839248346427494 1.0 1.0 38 P54646,Q13555,P54619,P04350,P17252,P63000,Q12959 7 +Fcgr3a mediated il10 synthesis 0.3575052127073734 0.1960024563856008 0.8446082433718045 1.0 1.0 7 P17252 1 +Postmitotic nuclear pore complex npc reformation 0.2788941207999268 0.1940927966107761 0.8461032218497448 1.0 1.0 24 P55735,Q9BTX1 2 +Costimulation by the cd28 family 0.3136554354942095 0.1937912867604197 0.8463393098393248 1.0 1.0 14 P42345,P63000,Q16512 3 +Dual incision in tc ner 0.2602623514898626 0.1932216464726023 0.8467853867335084 1.0 1.0 35 P18074,Q09472,P28340,P15927,P35244,Q9HCS7,Q9NR33 7 +Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.2946818011686349 0.1926961360245166 0.8471969497478726 1.0 1.0 18 Q09472,P51532,Q86U86,Q969G3,P67870 5 +Syndecan interactions 0.366218316505852 0.1912832685292656 0.8483036688429237 1.0 1.0 5 P17252 1 +Rho gtpases activate paks 0.3263466551605219 0.1908206728668759 0.8486660916784692 1.0 1.0 12 P35580,Q13177,P35240,Q16512,P63000 5 +Transcriptional regulation by ventx 0.3078959124191538 0.188466496330496 0.8505109769283801 1.0 1.0 15 Q9H1A4,Q9UJX5,Q9HCE1,Q9UJX4,Q9UJX2 5 +Rhog gtpase cycle 0.2600024328318112 0.1841946198499408 0.8538607800098414 1.0 1.0 34 O15173,Q13576,Q86UP2,P34897,Q13017,Q86XL3,P49257 7 +Rna polymerase i promoter escape 0.3021295250032244 0.1836489279982484 0.8542888768654546 1.0 1.0 16 P18074,P19447,P16104,Q9NYV6 4 +Regulation of cholesterol biosynthesis by srebp srebf 0.270440693429354 0.1823990776716331 0.8552695495765439 1.0 1.0 26 Q15126,Q16850,Q13907,P37268 4 +Signaling by robo receptors 0.2394503578623041 0.182369940495435 0.8552924142136116 1.0 1.0 139 Q14997,P62841,P61247,P62191,P62854,Q16512,Q92530,Q13177,Q9UNM6,O43242,Q15008,P61254,P62081,P46778,P55036,P18621,P50914,O00231,Q09161,P08865,P25398,P84098,P62917,P61289,O43347,P17252,P62266,P62899,P62750,P49721,P46782,O75122,P61513,Q02543,P62753,P15880,P46776,P27635,P63000 39 +Cellular response to hypoxia 0.2504030003033085 0.1789350338735053 0.8579887136457969 1.0 1.0 44 Q09472,Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,Q9NWT6,P49721,Q92530 11 +Fgfr2 alternative splicing 0.3047783481082172 0.1770432987911568 0.8594743792233688 1.0 1.0 15 P52597,Q09161,P35269,P30876,Q01085,P31483,P52272 7 +Intracellular signaling by second messengers 0.2439282223245594 0.174282105525578 0.8616437617473853 1.0 1.0 94 Q14997,P49815,P62191,Q13555,Q92530,Q9UNM6,O15111,O43242,P42345,Q15008,P55036,Q9NWH9,Q12873,P19174,O00231,P48426,Q9HCE1,P61289,P17252,P49721,P67870,P14373,P27361,P63000,Q8WXI9 25 +G1 s dna damage checkpoints 0.2503560097547735 0.1735741345103687 0.8622001610938788 1.0 1.0 42 Q14997,Q9UNM6,P24941,O00231,O43242,P62191,O14757,P61289,P55036,P49721,Q92530 11 +Processing of capped intronless pre mrna 0.2947965766314428 0.173283672174375 0.8624284572615972 1.0 1.0 17 Q86U42,Q09161 2 +Semaphorin interactions 0.2790384917288441 0.1708188057998628 0.8643662415174538 1.0 1.0 22 P35580,O94887,Q13464,Q13177,Q16512,P63000,Q9NWH9 7 +Rho gtpases activate cit 0.3356719797336196 0.1700274101622909 0.8649885803061355 1.0 1.0 9 P35580,O43663,Q15334,P35579,P63000 5 +Met promotes cell motility 0.3467655734172796 0.168868776738469 0.8658998590002276 1.0 1.0 7 Q9NWH9,P63000 2 +Budding and maturation of hiv virion 0.3301588437815193 0.1681889571351587 0.8664346281258568 1.0 1.0 10 Q96PU5 1 +Neddylation 0.2393712320767906 0.1670083587548044 0.8673634719628862 1.0 1.0 76 Q15345,Q14997,O00231,Q9H0A8,Q93034,Q96GG9,P61289,P55036,Q9BTE7,Q9UBW8,Q8NEZ5,P49721 12 +Intrinsic pathway for apoptosis 0.2817629822169448 0.1662130196092689 0.8679893137999317 1.0 1.0 20 Q9NR28,Q96FJ2 2 +Sema3a pak dependent axon repulsion 0.3442981399449323 0.1629453504790851 0.870561463444715 1.0 1.0 7 P63000,Q16512 2 +Negative regulation of nmda receptor mediated neuronal transmission 0.3360339223309126 0.1597148738098908 0.873105683708093 1.0 1.0 8 Q12959,Q13557,Q13555,Q15334 4 +Regulated necrosis 0.2777850832109754 0.1441011887264053 0.8854205660521623 1.0 1.0 19 Q14254,Q96FZ7,O75955,Q8WUX9,P09429,Q16543 6 +Vegfr2 mediated vascular permeability 0.3163036440898369 0.1436657505687792 0.885764417661552 1.0 1.0 11 P42345,P63000,Q13177,Q16512 4 +Constitutive signaling by ligand responsive egfr cancer variants 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1 +Signaling by egfr in cancer 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1 +Constitutive signaling by egfrviii 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1 +Mtor signalling 0.2985004491065197 0.1422637145958094 0.886871706518437 1.0 1.0 14 P54619,P54646,P62753 3 +Insulin receptor signalling cascade 0.3398887988678331 0.1393921132142917 0.8891403042625172 1.0 1.0 6 P27361 1 +Irf3 mediated induction of type i ifn 0.3369207772795299 0.133397537970313 0.8938789924227339 1.0 1.0 6 P13010,P78527,Q9UHD2,P49959,Q9UJV9 5 +Synthesis of pips at the early endosome membrane 0.3368961020398873 0.1333483786457596 0.8939178685753402 1.0 1.0 6 Q99570,Q08AM6 2 +Response of mtb to phagocytosis 0.3016945928052135 0.1333440946865429 0.8939212564259116 1.0 1.0 13 P27361,Q9H267,P23246,P14373 4 +Infection with mycobacterium tuberculosis 0.3016945928052135 0.1333440946865429 0.8939212564259116 1.0 1.0 13 P27361,Q9H267,P23246,P14373 4 +Regulation of pten stability and activity 0.2436594947614879 0.1310365759121241 0.8957463734552074 1.0 1.0 43 Q14997,Q9UNM6,O00231,P67870,O43242,P62191,P14373,P61289,P55036,P49721,Q92530 11 +Signaling by fgfr4 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1 +Signaling by fgfr3 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1 +Signaling by fgfr1 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1 +Sensing of dna double strand breaks 0.3346515787088439 0.125395638713521 0.9002103406664244 1.0 1.0 5 P49959,Q92993 2 +Pi5p regulates tp53 acetylation 0.3344153541541055 0.1249684531340022 0.9005485252659464 1.0 1.0 5 Q09472 1 +Cdt1 association with the cdc6 orc origin complex 0.2440448910981677 0.1231938769400102 0.9019535741300104 1.0 1.0 40 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,Q9UBD5,P49721,Q92530 10 +Separation of sister chromatids 0.2414121751132228 0.1221810873818135 0.90275560430964 1.0 1.0 111 Q14997,Q9UQE7,Q9UJX5,P62191,Q96FJ2,P55735,Q13409,P04350,Q71F23,O00139,Q92530,Q96EA4,Q9BZD4,Q9UNM6,O43242,Q15008,Q13257,Q14674,Q16763,P55036,Q9UJX4,Q9H1A4,O00231,P61289,Q9UJX2,P49721,O75122,P30622,Q96EE3 29 +Cytosolic trna aminoacylation 0.2649676830226847 0.1185063203187226 0.905666487496501 1.0 1.0 23 P54136,P49591,Q9Y285,P41250,P49589,P23381,Q12904 7 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.2899042266310131 0.1159545517014216 0.9076885612316504 1.0 1.0 14 Q99873,Q09472,Q9HCE1 3 +Snrnp assembly 0.2411105713988063 0.1136241719390093 0.9095357250059448 1.0 1.0 42 Q09161,P12270,Q8N1F7,O14744,P55735,Q96EE3,Q9BTX1 7 +Fceri mediated nf kb activation 0.2396707206673632 0.1128595749775059 0.9101418859952104 1.0 1.0 46 O15111,Q14997,P55036 3 +Rna polymerase i transcription 0.2548187820246729 0.1119032410928589 0.9109001267268168 1.0 1.0 27 P18074,Q12873,Q9NYV6,P16104,Q13185,P27361,P19447,Q8WXI9 8 +Glutamate and glutamine metabolism 0.318090283469961 0.1073353910066212 0.9145229087477692 1.0 1.0 7 P00367,Q96C36 2 +Cell cycle 0.2104303864032934 0.1049208457506984 0.9164386177456 1.0 1.0 313 P00374,P28340,O43242,O95067,Q9UJX4,Q9Y2S7,Q13561,Q14566,Q9UJX2,Q86XI2,P30622,P27361,P02545,Q8WVB6,Q9BTX1,Q14997,Q86XL3,Q8WUX9,P55735,P42695,Q13409,Q99996,O95235,P25205,Q9BZD4,Q00534,Q14674,Q16763,P55036,P51530,O60763,P33991,Q9UBD5,P49721,P67870,P04818,Q92547,Q96EE3,O15504,P04183,P62191,Q96FJ2,P49959,Q8WXH0,P04350,Q71F23,Q92993,Q92530,Q96EA4,Q99986,Q9UNM6,P15927,Q15008,Q13257,Q9H1A4,P24941,P17252,Q08379,O75330,Q09472,Q9UQE7,Q9UJX5,P23258,O00139,Q9BRT9,Q9NR33,O00231,P12270,O14757,P16104,P35244,P61289,Q9UIS9,O75122,P20700,P33992,P54132,Q9BSJ2,Q8N1F7 79 +Condensation of prophase chromosomes 0.2964202651022088 0.10411383262999 0.9170790136656616 1.0 1.0 12 P16104,Q86XI2 2 +Rora activates gene expression 0.3205773748898018 0.1016452944344779 0.9190382258498682 1.0 1.0 5 Q09472 1 +Diseases of mismatch repair mmr 0.3207499187689179 0.1012126938351652 0.9193816202420686 1.0 1.0 4 P20585 1 +Downregulation of erbb2 signaling 0.3128526293327923 0.0978294133828551 0.9220677509025464 1.0 1.0 7 Q93034 1 +Formation of the early elongation complex 0.2724817267459818 0.094690108005616 0.924560975340555 1.0 1.0 17 P18074,Q09161 2 +Regulation of glucokinase by glucokinase regulatory protein 0.2490777802277642 0.0918226449628226 0.9268389519876912 1.0 1.0 28 P55735,P12270,Q96EE3,Q9BTX1 4 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.284892137586845 0.0877560164570934 0.9300705966178868 1.0 1.0 13 Q8WXI9,Q12873,P16104,Q13185 4 +Gene silencing by rna 0.2353595140768989 0.0855136586056253 0.9318530372493246 1.0 1.0 46 P12270,P16104,P55735,Q96EE3,Q9Y2W6,Q9BTX1 6 +Rac3 gtpase cycle 0.2419209275364532 0.0830593999487353 0.9338043083984476 1.0 1.0 34 O15173,Q13177,Q13017,P49257,Q9Y2A7,O15498,Q9UQB8,Q16512,Q68EM7,Q01968 10 +Gastrin creb signalling pathway via pkc and mapk 0.3052720551988033 0.0794638758663469 0.9366636636040284 1.0 1.0 6 P17252 1 +Nucleotide salvage 0.2946136964617297 0.0777527333727515 0.9380247458680628 1.0 1.0 9 Q9P2T1,P55263 2 +Darpp 32 events 0.2920474581071228 0.0777397842164232 0.9380350466215288 1.0 1.0 10 P17252 1 +Dna damage reversal 0.2990737974305271 0.0734947891980899 0.9414123904804914 1.0 1.0 4 Q9H1I8,Q8N3C0,Q6P6C2 3 +Metabolism of polyamines 0.2356518007755824 0.0692155078707298 0.9448180792159632 1.0 1.0 39 Q14997,Q9UNM6,O00231,O43242,P62191,P19623,P61289,P55036,P49721,Q92530 10 +Nuclear events kinase and transcription factor activation 0.2703426389496062 0.0642419886175683 0.9487775443426048 1.0 1.0 14 Q09472,P50570 2 +Sumoylation of chromatin organization proteins 0.2352412713338293 0.0626599397094621 0.950037298155515 1.0 1.0 38 Q12873,P12270,P55735,Q96EE3,Q9BTX1 5 +Irs mediated signalling 0.2844338213325297 0.0588022763667877 0.9531095953216472 1.0 1.0 4 Q99570,Q06124,P31751 3 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.2845188284518759 0.0559759525115533 0.9553609642336274 1.0 1.0 5 Q99570,O14654,Q06124,P31751 4 +Recognition of dna damage by pcna containing replication complex 0.2517816801414998 0.0552198214100894 0.9559633378252212 1.0 1.0 20 P28340,Q9NR33,P15927,P35244 4 +Neuronal system 0.2256370245837584 0.0540356285574042 0.956906778211716 1.0 1.0 55 Q9Y2J2,O14795,Q14254,P21964,Q13555,P54646,P54619,P04350,P17252,P63000,Q12959 11 +Negative regulation of fgfr1 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5 +Negative regulation of fgfr4 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5 +Negative regulation of fgfr2 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5 +Negative regulation of fgfr3 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5 +Spry regulation of fgf signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5 +Downstream signaling events of b cell receptor bcr 0.2293751219258552 0.0499875819060378 0.9601322841542548 1.0 1.0 46 O15111,Q14997,P55036 3 +Translesion synthesis by polh 0.2672123635564776 0.04831240639014 0.9614672672309617 1.0 1.0 13 P15927,Q8TAT6 2 +Hiv life cycle 0.2266407456473269 0.0447870836172544 0.964277020542817 1.0 1.0 84 P18074,Q09161,Q14241,Q96PU5,Q8WUX9,P18615,P55735,Q96EE3,P55199,P17096,Q9BTX1 11 +Formation of tubulin folding intermediates by cct tric 0.262432594367899 0.0391321581201664 0.9687850221250918 1.0 1.0 13 P49368,Q9BVA1,Q9BUF5,P50991,Q99832,P17987,Q13885,P68371,P50990,P04350,P40227,P78371 12 +Sumoylation of sumoylation proteins 0.2339430412350507 0.0389897143938711 0.9688985891041426 1.0 1.0 30 P55735,P12270,Q9BTX1,Q96EE3 4 +Signaling by notch1 pest domain mutants in cancer 0.2655688622754458 0.0360393285917254 0.9712509996290172 1.0 1.0 11 Q09472,Q06330,Q9UBN7,O75376,P63208,Q92793,Q92769,Q92542,Q13616,Q13547 10 +Notch hlh transcription pathway 0.26533054142985 0.0351865940699098 0.9719309519950856 1.0 1.0 8 Q06330,Q9UBN7,O75376,Q92793,Q92769,Q04721,Q13547 7 +Traf6 mediated irf7 activation 0.2651658045436415 0.0346825408026546 0.972332882972646 1.0 1.0 7 Q09472,Q9C037,Q12933,Q14258 4 +Rac2 gtpase cycle 0.2309749768201215 0.0344935087407608 0.9724836185442782 1.0 1.0 35 O15173,Q13505 2 +Ca dependent events 0.2656136882790748 0.034493286458576 0.9724837957943246 1.0 1.0 9 P17252 1 +Bbsome mediated cargo targeting to cilium 0.2618834080717589 0.0331836141490099 0.9735281649414482 1.0 1.0 6 P49368,P50991,P17987,P50990,P78371 5 +Regulation of tp53 activity 0.2223969819583501 0.0317710823316983 0.9746546079461113 1.0 1.0 58 Q09472,Q12873,Q92547,P24941,P67870,P15927,P42345,P48426,P54646,O14757,P35244,O14744,P54132,P54619,P51530,Q92993,Q8WXI9 17 +Folding of actin by cct tric 0.2620400837571012 0.0317557908558672 0.9746668026253338 1.0 1.0 8 P49368,P50991,Q99832,P17987,P50990,P40227,P78371 7 +Regulation of expression of slits and robos 0.2316231664520089 0.0316907144040486 0.9747187000010864 1.0 1.0 124 Q14997,P62841,P61247,P62191,P62854,Q92530,Q9UNM6,O43242,Q15008,P61254,P62081,P46778,P55036,P18621,P50914,O00231,Q09161,P08865,P25398,P84098,P62917,P61289,O43347,P62266,P62899,P62750,P49721,P46782,P61513,Q02543,P62753,P15880,P46776,P27635 34 +Signaling by erbb2 in cancer 0.2487344436510397 0.0294411260342475 0.9765127731763232 1.0 1.0 5 Q16543 1 +Signaling by erbb2 ecd mutants 0.2487344436510397 0.0294411260342475 0.9765127731763232 1.0 1.0 5 Q16543 1 +Negative regulation of the pi3k akt network 0.2521526062475964 0.0287076607088995 0.977097746525 1.0 1.0 15 P63000,P27361,P48426,Q9NWH9 4 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.2318494173886989 0.0278803058747574 0.9777576159727106 1.0 1.0 4 P27361,P28482,P31751 3 +Degradation of gli1 by the proteasome 0.2252213705880999 0.0250031042149009 0.9800524875783578 1.0 1.0 42 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,P49721,P17252,Q92530 10 +Negative regulation of mapk pathway 0.2574993298073603 0.0245902454422323 0.9803817999579711 1.0 1.0 11 P36507 1 +Cytokine signaling in immune system 0.2086683602950439 0.0242761154816462 0.9806323646003364 1.0 1.0 186 P14174,Q14997,O15111,P08670,P09429,P09601,O15344,P55735,Q96EE3,P55036,Q13126,P26038,Q00169,P49721,Q9BTX1 15 +Translation of sars cov 2 structural proteins 0.2433591354339924 0.0228411977214195 0.9817769455578892 1.0 1.0 18 P04844,P78362,Q99873,Q10472 4 +Protein protein interactions at synapses 0.2497838508831805 0.0221004495668545 0.9823678278620812 1.0 1.0 14 Q9Y2J2,Q15334,Q14254,O75955,Q12959 5 +Rmts methylate histone arginines 0.238723231558749 0.0205222105493968 0.9836267943501112 1.0 1.0 22 O14744,Q99873,Q969G3,P16104 4 +Pten regulation 0.2224971794625215 0.0193113852421122 0.984592701513164 1.0 1.0 67 Q14997,Q12873,Q9UNM6,O00231,P67870,O43242,P42345,P62191,P14373,P27361,Q9HCE1,P61289,P55036,P49721,Q92530,Q8WXI9 16 +Traf3 dependent irf activation pathway 0.2365465873484706 0.0182723175597645 0.9854216111663764 1.0 1.0 6 Q09472,Q9C037,Q14258 3 +Aquaporin mediated transport 0.245959829721712 0.0175554045710274 0.9859935331851972 1.0 1.0 8 P17252 1 +Degradation of axin 0.2264025361907124 0.0175058198590895 0.986033089982489 1.0 1.0 37 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,P49721,Q92530 9 +Mitochondrial trna aminoacylation 0.2409521970819756 0.0172101742019714 0.9862689455525876 1.0 1.0 18 Q9HA77 1 +Transcriptional regulation by mecp2 0.2381506992723469 0.0165081135649231 0.9868290292819746 1.0 1.0 20 P17252,Q9HCE1,Q9NWH9,Q13555 4 +Fanconi anemia pathway 0.2461043841595118 0.0145708001818474 0.988374594859324 1.0 1.0 9 P15927 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.225584991072566 0.0139304877238149 0.988885438401047 1.0 1.0 37 Q9Y4I1,P54646,Q12846,P54619,Q8IYI6,Q9UPT5,P04350,P35579,P63000 9 +Thrombin signalling through proteinase activated receptors pars 0.2305622009569376 0.0113343265162199 0.9909567094933605 1.0 1.0 7 P29992,P62873,P27361,Q14344,P28482,Q9UBI6 6 +Signaling by notch 0.2199807218310375 0.0094686321087773 0.9924452375156838 1.0 1.0 63 Q09472,P67809,Q9UNM6,O00231,O43242,P62191,P16104,Q9UBN7,Q9HCE1,P61289,P55036,P49721,P16615,Q92530 14 +Sars cov 2 infection 0.2286103901683352 0.0055551520896669 0.9955676527115837 1.0 1.0 26 P78362,Q99873,Q8WUX9 3 +Sumoylation of ubiquitinylation proteins 0.2244499939306571 0.0019355002589282 0.9984556951901736 1.0 1.0 31 P12270,P55735,Q96EE3,Q9BTX1,Q8N1F7 5 +Gap junction trafficking and regulation 0.2379964523887378 0.0012115629075325 0.999033312898136 1.0 1.0 12 P04350 1 +Suppression of phagosomal maturation 0.1961722488038293 0.0006820042936855 0.9994558393458512 1.0 1.0 7 Q9H267,Q9UI12,P51149,P20339,P52294,Q14974 6 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0c93b8a3c043d224a85e161792d51ba18b5482c6 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the phototransduction cascade", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell cycle genes", "Foxo mediated transcription of cell death genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Histidine catabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of function of smad2 3 in cancer", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates bcl2l11 bim transcription", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory perception of taste", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "APIP", "APLP2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BCR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CENPF", "CENPI", "CENPU", "CERS2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLINT1", "CLIP1", "CLNS1A", "CLSPN", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT7", "CNOT9", "COASY", "COG2", "COG7", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPH1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTA", "FNTB", "FOXK1", "FOXK2", "FPGS", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT5", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMD1", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8C", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAVS", "MBD1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "MFN1", "MFN2", "MGA", "MGAT2", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIOS", "MIPEP", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO5A", "MYO6", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NF2", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NIT2", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR2F1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PELP1", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REL", "RELA", "REPS1", "RETSAT", "REV1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3RF1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLIT2", "SLK", "SLTM", "SMAD4", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOD2", "SORD", "SORT1", "SPAG9", "SPC25", "SPCS2", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM115", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TNRC6B", "TOLLIP", "TOM1", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT61A", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSPO", "TSR1", "TSR3", "TST", "TSTA3", "TTC26", "TTC37", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPC", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZEB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCB10", "ABCD3", "ACADVL", "ACOX3", "ACSF3", "ACTN1", "ACTR2", "ADD3", "ADK", "AIMP1", "AK6", "AKAP9", "AKT2", "ALDH3A2", "ALG11", "ALG5", "ALG9", "ALKBH5", "ANAPC1", "ANAPC4", "ANAPC5", "ANKFY1", "ANKLE2", "APEX1", "APIP", "APLP2", "ARCN1", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARIH2", "ARPC1A", "ARPC4", "ASCC2", "ASCC3", "ASNA1", "ATP11C", "ATP13A1", "ATP2A2", "ATP5A1", "ATP5B", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1H", "BAG4", "BAIAP2", "BCAP31", "BCR", "BLM", "BLVRA", "BLVRB", "BRD2", "BSG", "CALD1", "CALU", "CAMK2D", "CAMK2G", "CAPZA1", "CAPZA2", "CARS", "CARS2", "CASP8", "CBFB", "CBL", "CBX1", "CBX3", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CDC23", "CDC37", "CDC42BPB", "CDC6", "CDK1", "CDK2", "CDK6", "CENPU", "CERS2", "CHCHD3", "CHD1L", "CHD3", "CHEK1", "CHKA", "CHMP6", "CHMP7", "CHTF18", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKB", "CLASP2", "CLIP1", "COG7", "COL4A3BP", "COMMD4", "COMT", "COPG2", "COPS3", "COPS7A", "COPZ1", "COX6B1", "CPSF7", "CREBBP", "CS", "CSNK2B", "CTNNA1", "CTU2", "CUL1", "CUL4B", "CUL5", "CYFIP2", "CYP51A1", "DAGLB", "DCP1A", "DCTN2", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDRGK1", "DDX41", "DHCR24", "DHFR", "DIABLO", "DLG1", "DLG3", "DNA2", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DOHH", "DST", "DTX3L", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECSIT", "ECT2", "EEA1", "EEF1D", "EEF2", "EEFSEC", "EHHADH", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3E", "EIF5", "ELL", "ELOA", "EMC3", "EP300", "EPB41L3", "ERCC2", "ERCC3", "ESPL1", "EXOC7", "EXOC8", "EXOSC1", "EXOSC7", "EZR", "FADS2", "FAF2", "FAM114A2", "FAM98B", "FARP2", "FARSA", "FASN", "FBXO22", "FDFT1", "FEN1", "FERMT2", "FLOT1", "FLOT2", "FNTA", "GALNT1", "GARS", "GATAD2B", "GBA", "GCC2", "GET4", "GFM1", "GFPT1", "GGCX", "GINS4", "GLUD1", "GMPPB", "GMPR2", "GNA11", "GNA13", "GNB1", "GNG12", "GOLGA2", "GOLGA5", "GOLGB1", "GPSM1", "GSR", "GTF2F1", "GTF2H4", "GTPBP3", "GYG1", "H2AFX", "HDAC1", "HDAC2", "HDAC6", "HIF1AN", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMMR", "HMOX1", "HMOX2", "HNRNPF", "HNRNPM", "HSD17B4", "HSP90AB1", "ICMT", "IDI1", "INTS13", "INTS3", "INTS4", "INTS6", "INTS9", "IQGAP2", "IRS4", "ITSN2", "JMJD6", "KAT5", "KDELR1", "KDSR", "KIAA0391", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "KLC2", "KPNA1", "KPNB1", "KTN1", "LCMT2", "LGALS3", "LIG1", "LIG3", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LRRC41", "MAD2L1", "MAN1A1", "MANF", "MAP2K2", "MAPK1", "MAPK3", "MAPK7", "MBD1", "MCM3", "MCM4", "MCM5", "MCM6", "MCRS1", "MECP2", "MED1", "METAP1", "METAP2", "MFN2", "MID1", "MIF", "MIOS", "MOV10", "MPG", "MPRIP", "MRE11", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL28", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSH3", "MSI1", "MSMO1", "MSN", "MTAP", "MTCH1", "MTIF2", "MTMR2", "MTOR", "MTX1", "MTX2", "MYDGF", "MYH10", "MYH9", "MYO5A", "NAGK", "NAMPT", "NANS", "NAPG", "NCAPD3", "NCAPG2", "NCBP1", "NCKAP1", "NCOR1", "NCSTN", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NELFE", "NF2", "NIPSNAP2", "NOTCH2", "NPLOC4", "NSFL1C", "NUCB1", "NUF2", "NUP93", "NUPL2", "OCRL", "OPA1", "ORC3", "ORC5", "OSBPL1A", "OTUD7B", "P3H1", "PABPN1", "PACSIN2", "PACSIN3", "PAK2", "PARP1", "PARP2", "PBRM1", "PEX14", "PEX19", "PEX5", "PFDN4", "PGM2", "PGRMC2", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PIGK", "PIK3R4", "PIP4K2A", "PITPNA", "PKN1", "PLCG1", "PLD3", "PLK1", "PLOD3", "PLS1", "PMPCA", "PMVK", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE4", "POLR2B", "POLRMT", "PPP1CA", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PRC1", "PRCP", "PRKAA2", "PRKAG1", "PRKCA", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PSAP", "PSMB2", "PSMC1", "PSMD11", "PSMD13", "PSMD3", "PSMD4", "PSMD6", "PSME3", "PSME4", "PSMF1", "PTCD3", "PTPN11", "PUS1", "PYCR2", "QKI", "RAB27A", "RAB3GAP2", "RAB4A", "RAB5A", "RAB7A", "RAB9A", "RABGEF1", "RAC1", "RAD23A", "RAD50", "RARS", "RARS2", "RBPJ", "RCN1", "RDX", "RETSAT", "REV1", "RFC1", "RFC3", "RINT1", "RIOX2", "RNF20", "ROCK1", "ROCK2", "RP2", "RPA2", "RPA3", "RPL10", "RPL11", "RPL14", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL3", "RPL31", "RPL37A", "RPL5", "RPL8", "RPN1", "RPN2", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS23", "RPS25", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "RRN3", "SARM1", "SARS", "SCARB1", "SCARB2", "SCCPDH", "SEC11A", "SEC13", "SEC23A", "SEH1L", "SEPT2", "SEPT7", "SF3B5", "SFPQ", "SHMT2", "SHTN1", "SKP1", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A26", "SLC25A32", "SLC25A4", "SLTM", "SMAD4", "SMARCA4", "SMARCE1", "SMC3", "SMG5", "SNU13", "SORD", "SPDL1", "SPTAN1", "SPTBN1", "SQOR", "SRM", "SRP19", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRB", "SSBP1", "SSR1", "SSR4", "STAMBP", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRN", "STX18", "STX4", "SYNE2", "TAB1", "TARS2", "TBC1D10B", "TBK1", "TCP1", "TDRKH", "TFAM", "TIA1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM44", "TIMM8B", "TK1", "TKFC", "TMED10", "TMED7", "TOMM22", "TOMM5", "TOPBP1", "TOR1AIP1", "TPM3", "TPM4", "TPP1", "TPR", "TRAF2", "TRAPPC11", "TRAPPC8", "TRIM25", "TRIM27", "TRIM4", "TRMT61A", "TSC2", "TSN", "TSTA3", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TXNRD1", "TYMS", "UBA5", "UBE2S", "UFL1", "UGP2", "UNC13B", "UNG", "UQCR10", "UQCRC2", "USO1", "UTRN", "VAC14", "VBP1", "VCP", "VDAC1", "VDAC2", "VIM", "VPS33B", "VPS45", "VPS52", "VRK1", "WARS", "WDR6", "XAB2", "XIAP", "XRCC1", "XRCC5", "YBX1", "YIF1A", "YKT6", "YME1L1", "YY1"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e94f2e96576239dc539c5da5dd41c9716aad8d24 --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Retinoblastoma gene in cancer", "1": "Vasopressinregulated water reabsorption", "2": "Sphingolipid pathway", "3": "Progeriaassociated lipodystrophy", "4": "Sphingolipid metabolism in senescence"} \ No newline at end of file diff --git a/msigdb_wp/advanced/plot_0.png b/msigdb_wp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..95874a48ea1e1cd86181f35cb287d4d15f5dd010 --- /dev/null +++ b/msigdb_wp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:969890ba89317f86d3aac5c16c6ed373b6a764c4063814ac4727649271c336d3 +size 209794 diff --git a/msigdb_wp/advanced/plot_1.png b/msigdb_wp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4df8b36c2c38fcf7eb3a784862255ccd0e0dadf8 --- /dev/null +++ b/msigdb_wp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0869bc3686acb730e6bd3064282f8883ef8ff4b8c758c1924b1c766270eed66f +size 201002 diff --git a/msigdb_wp/advanced/plot_2.png b/msigdb_wp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7a357e5ef6e6835cc4dfdc55319714513b934512 --- /dev/null +++ b/msigdb_wp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7786a0ae061258895d06a56b958cfe5a40a2a94b40e87ce2fa776d9a6ac78186 +size 199066 diff --git a/msigdb_wp/advanced/plot_3.png b/msigdb_wp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..04051a6c2d6a52fc8ec7c42c986f9b027ae2201e --- /dev/null +++ b/msigdb_wp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:221cdcef2b02fd31bc38e4133c58a8b0568504ece4901ea4e447f4fcff7bef75 +size 200078 diff --git a/msigdb_wp/advanced/plot_4.png b/msigdb_wp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7f02d0adc5013d74749275d0cf08f14d949bf779 --- /dev/null +++ b/msigdb_wp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9d39db4bbba6c33a658f34a93de50bec71d59db5a3e7e7abcfd442a171ab517 +size 205907 diff --git a/msigdb_wp/basic/idx2term.json b/msigdb_wp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..da892a70e8d292d6203f724214b9c2c03e90dc2f --- /dev/null +++ b/msigdb_wp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Retinoblastoma gene in cancer", "1": "Vasopressinregulated water reabsorption", "2": "Sphingolipid pathway", "3": "Progeriaassociated lipodystrophy", "4": "Sphingolipid metabolism in senescence", "5": "Cholesterol metabolism with bloch and kandutschrussell pathways", "6": "Hippo signaling regulation pathways", "7": "Influence of laminopathies on wnt signaling", "8": "Familial partial lipodystrophy fpld", "9": "Nonsmall cell lung cancer", "10": "Electron transport chain oxphos system in mitochondria", "11": "Regulation of actin cytoskeleton", "12": "Pdgf pathway", "13": "G1 to s cell cycle control", "14": "Base excision repair", "15": "Cell cycle", "16": "Spinal cord injury", "17": "Nonalcoholic fatty liver disease", "18": "Mitochondrial complex i assembly model oxphos system", "19": "Met in type 1 papillary renal cell carcinoma", "20": "Cholesterol biosynthesis pathway", "21": "Mirna regulation of dna damage response", "22": "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "23": "Circadian rhythm genes", "24": "Dna damage response", "25": "Egfr tyrosine kinase inhibitor resistance", "26": "Target of rapamycin tor signaling", "27": "Gastrin signaling pathway", "28": "Netrinunc5b signaling pathway", "29": "Cardiac hypertrophic response", "30": "Pi3kakt signaling pathway", "31": "Metapathway biotransformation phase i and ii", "32": "Erbb signaling pathway", "33": "Kit receptor signaling pathway", "34": "Glioblastoma signaling pathways", "35": "Pancreatic adenocarcinoma pathway", "36": "Thyroid stimulating hormone tsh signaling pathway", "37": "Sterol regulatory elementbinding proteins srebp signaling", "38": "Vegfavegfr2 signaling pathway", "39": "Fas ligand pathway and stress induction of heat shock proteins", "40": "Micrornas in cardiomyocyte hypertrophy", "41": "Energy metabolism", "42": "Joubert syndrome", "43": "Modulators of tcr signaling and t cell activation", "44": "Phosphoinositides metabolism", "45": "Tcell receptor tcr signaling pathway", "46": "Dna replication", "47": "Alzheimers disease", "48": "Camkk2 pathway", "49": "Alzheimers disease and mirna effects"} \ No newline at end of file diff --git a/msigdb_wp/basic/plot_0.png b/msigdb_wp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1f8d5ae60cbf1ccacaa981fc900c2feaab48351c --- /dev/null +++ b/msigdb_wp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c3a48d20a1c09d3284dfd84e47476faabec0803e5a03a77e505783e2919cee4 +size 152711 diff --git a/msigdb_wp/basic/plot_1.png b/msigdb_wp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..83457549ae60fc5de92d61671a231c8b16d49270 --- /dev/null +++ b/msigdb_wp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91a274beb2ee2ffab5c177ceff897e46b6cdb27ee51cfeda6b80673ed2e3c2f3 +size 142912 diff --git a/msigdb_wp/basic/plot_10.png b/msigdb_wp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..6fe7cb6fb5bf9df2db08c73c8e30db82d4ca40aa --- /dev/null +++ b/msigdb_wp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e59b58fb33aa5e7b46ad58a9301e57d4e54a429327b3fdbf9cf0595088ce97ac +size 150170 diff --git a/msigdb_wp/basic/plot_11.png b/msigdb_wp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..b01de4438cfffa4440a1aa0fee01e64db3dd826b --- /dev/null +++ b/msigdb_wp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20ff0e7856a794ff2356b4f683ca23b1cbcbc18e9d9e939fbec893d687da25cf +size 147134 diff --git a/msigdb_wp/basic/plot_12.png b/msigdb_wp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..a4dace35421a056e5f461e7940f18d8983bae515 --- /dev/null +++ b/msigdb_wp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79b58e4f05c84606113c460c104697683470d154ae6f05418fb42705f45b14a8 +size 131649 diff --git a/msigdb_wp/basic/plot_13.png b/msigdb_wp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..afdfbab650deb12b4e1fff1303dff6be0fa6a620 --- /dev/null +++ b/msigdb_wp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9a4edf443eef40d10a44f14a3b7e9fc62fad41a91bade22280fb50405631f38 +size 140100 diff --git a/msigdb_wp/basic/plot_14.png b/msigdb_wp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..6edd7fb3f1034cacf6254f9b0652785f14c7bf73 --- /dev/null +++ b/msigdb_wp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f05cc5021bbf2a9a0aee655ed21cf08957917622ba5573fbe7dd037f9fe8d190 +size 132582 diff --git a/msigdb_wp/basic/plot_15.png b/msigdb_wp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..eb137f830b31068b55cc918f4a3a3c62188b55fc --- /dev/null +++ b/msigdb_wp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:798e951a061cdf809f5c12c292988624469637eba14457f5db31a399d2a5d6c6 +size 138166 diff --git a/msigdb_wp/basic/plot_16.png b/msigdb_wp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..dc11424a93123a0db98f917a884299bffc7c231e --- /dev/null +++ b/msigdb_wp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4739de334f176590508aaaa52376c9b1c877777c35d446e99bc3bc26630a159 +size 125728 diff --git a/msigdb_wp/basic/plot_17.png b/msigdb_wp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..b8f6498d6aa7eb16f38b39bbf541d0d8ddc5a636 --- /dev/null +++ b/msigdb_wp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2acf4e26012b0622ebefb8a2ee1392c7bc1703fdc5ecb87e0dc73d1883a2d7b +size 144888 diff --git a/msigdb_wp/basic/plot_18.png b/msigdb_wp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..97074a356bee3d3a7bb11333dd7d58e72ac77ecd --- /dev/null +++ b/msigdb_wp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7919ef9aae1b6ee40a40897b55de650766f9cf4d133b8c81751fa23ec3367435 +size 146888 diff --git a/msigdb_wp/basic/plot_19.png b/msigdb_wp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..66ff3baf1082dc3f7130b1c285f5a03a04cea655 --- /dev/null +++ b/msigdb_wp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1895a1b81f23f74c248760f9ceee9e85c60593cc560960cc8d48670b7a0be7cb +size 136165 diff --git a/msigdb_wp/basic/plot_2.png b/msigdb_wp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6ce76f1b77562f2d61235c4c5be55f5a0df5add7 --- /dev/null +++ b/msigdb_wp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:76a23ce44bddc96fb144415dd151528be046bd631a5583536acf21181595d0b1 +size 134961 diff --git a/msigdb_wp/basic/plot_20.png b/msigdb_wp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..d32971bf28641e3c508315852f689dfac513b883 --- /dev/null +++ b/msigdb_wp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89c52975d4d6330f08379a843dae3feca96b21c32cf47c6d2bc76f0a83e3a2ef +size 139907 diff --git a/msigdb_wp/basic/plot_21.png b/msigdb_wp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..796247c97163b6fe5216bde7ec91773d3a6f503e --- /dev/null +++ b/msigdb_wp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f035a5b81893f2d393fe13b0e64a91bb640df8cf6efc707ca2aeefb79bfa514f +size 152025 diff --git a/msigdb_wp/basic/plot_22.png b/msigdb_wp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..0d6484f5e87e8512fa296e306a22761d01e43078 --- /dev/null +++ b/msigdb_wp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6bbfc0903233918b65f5d9a3c6845b7b9354ae464a58b7ca6bf2d550bc6b3472 +size 148446 diff --git a/msigdb_wp/basic/plot_23.png b/msigdb_wp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..a0994c0c9faae1ac8b1028544237387ab9d89a23 --- /dev/null +++ b/msigdb_wp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac4253fd62f441839d699f3fbea647496fde9aa8299f626894b9f22e3c237dfb +size 143210 diff --git a/msigdb_wp/basic/plot_24.png b/msigdb_wp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..25015fc97ad34b401033a24979f19645f32b1109 --- /dev/null +++ b/msigdb_wp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1777ed6a3e9b59af5abd9f521c3882ee8da5a4809f65cfd02caaec3439ff78cd +size 143443 diff --git a/msigdb_wp/basic/plot_25.png b/msigdb_wp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..9ff38d8cf2c99c87cec62baff25ac9471b785fa1 --- /dev/null +++ b/msigdb_wp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ca3b66e06aff108ddf455e38dc9e39ccf754dc8c2da5b74549544016af9a17f +size 148974 diff --git a/msigdb_wp/basic/plot_26.png b/msigdb_wp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..cee4ab810aa36e4956f9195ec197710c7218388f --- /dev/null +++ b/msigdb_wp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3d2f0ca065baa119a7173cda7f2e87b20e12e8bf4e33356031cde47c8f79eb9 +size 138875 diff --git a/msigdb_wp/basic/plot_27.png b/msigdb_wp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..3561ef6774c303fdb8e5e256ac0a6b42d890098e --- /dev/null +++ b/msigdb_wp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29e0a89f4bd79142d68a232d56cd6f56751469d1a2c347c0b96889e8f4e0e3ec +size 146546 diff --git a/msigdb_wp/basic/plot_28.png b/msigdb_wp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..8248c2975ec2fc9772cb169622843da2ce5c8e2a --- /dev/null +++ b/msigdb_wp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:896e4ff7db95c834ee6ae917c63f04ebb6e7cf48bc6b155f6b1ac890e005b681 +size 138985 diff --git a/msigdb_wp/basic/plot_29.png b/msigdb_wp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..f0fdbb05fd585fa38092726022ab5eb8c8f93a90 --- /dev/null +++ b/msigdb_wp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64b0c438e49b0201098673edc9e5279d6da47bdd83fcbe2a5d0010b9b4da480d +size 150647 diff --git a/msigdb_wp/basic/plot_3.png b/msigdb_wp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d7304ddfe2b4282c0d6d34f4e7e3c08ebdd73552 --- /dev/null +++ b/msigdb_wp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:deb4a1c655a747b85dd0e875669b46a7acf6abed520364153cacaaad7c0ca729 +size 141498 diff --git a/msigdb_wp/basic/plot_30.png b/msigdb_wp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..86e1299225f876b3008ef53c2877b3e00b1ffe95 --- /dev/null +++ b/msigdb_wp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d3aaa934d7ff08708c9173398943d8e9c41a2514a5a0e06c4075a4bffa3ee06 +size 138027 diff --git a/msigdb_wp/basic/plot_31.png b/msigdb_wp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..34663d7679a028becd29c7a07cfd0b91e40a3b68 --- /dev/null +++ b/msigdb_wp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ddfbce31b9b3af12fc8bbfc5660c3940506153b19fb737d7f0df9d6831efa72 +size 153775 diff --git a/msigdb_wp/basic/plot_32.png b/msigdb_wp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..0eed25744fc7a612bf652031f61cd0061b166c76 --- /dev/null +++ b/msigdb_wp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:73168b0913f69ca44ddc77e882e901c3ac421e669328896683f7438580d8ae05 +size 142509 diff --git a/msigdb_wp/basic/plot_33.png b/msigdb_wp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..a548d52f832bf4a93af20a8abb4a4deb4d45d1df --- /dev/null +++ b/msigdb_wp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:176ae41301c2658e3b6f19723d63c382958364b4b212d95416c923327a927066 +size 151120 diff --git a/msigdb_wp/basic/plot_34.png b/msigdb_wp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..cf9e196084c89fb1b8c9f204b5a0f79edc62a2ea --- /dev/null +++ b/msigdb_wp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14c49cf93929ad9fa7b0fdcadce8f1af6884ca764aeeb04eb49bac346c1f5148 +size 154138 diff --git a/msigdb_wp/basic/plot_35.png b/msigdb_wp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..d931ffb8aa6719c3351095c3cbf66b53c7a1e977 --- /dev/null +++ b/msigdb_wp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:116879abca46b06dbc8f6611df847b1706a63f1d5ad71196609e40f601c73fcd +size 152298 diff --git a/msigdb_wp/basic/plot_36.png b/msigdb_wp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..df3cb15284fa2bca11a5a976f07b368c28a4ce0b --- /dev/null +++ b/msigdb_wp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:757b32d658926e6e4c799115157798e2c9d39ef69410dadd699150722aef0fe7 +size 153254 diff --git a/msigdb_wp/basic/plot_37.png b/msigdb_wp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..5c006715d578fee298e1e4916186508c927daa29 --- /dev/null +++ b/msigdb_wp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c0e85dbf0de61c05acbd8196125b94e508a4512dc9c4ea4930fa2701c88a411 +size 154317 diff --git a/msigdb_wp/basic/plot_38.png b/msigdb_wp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..5d7f1eaa652249a41837cba17b57be25a9985a44 --- /dev/null +++ b/msigdb_wp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50a51982dfb2358abf327fc64f0de2dacba78e4c1a829f66464a0a68aa35244b +size 151688 diff --git a/msigdb_wp/basic/plot_39.png b/msigdb_wp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..15a3dd473f91d52e704acadd29104094ee512630 --- /dev/null +++ b/msigdb_wp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:186823b9199c13c134dd54308b099716a87722299e0be58146fc4cffbd1c1a4a +size 155271 diff --git a/msigdb_wp/basic/plot_4.png b/msigdb_wp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..be78e7d4f027543affc71c66bbafab2b97394cf3 --- /dev/null +++ b/msigdb_wp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cc1addf04fca070f721551f44ad85e8282a0cdee4c35f32606c1936cada0f01 +size 137090 diff --git a/msigdb_wp/basic/plot_40.png b/msigdb_wp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..30aeff2138645531f1039fc758e11c8d6a702fd4 --- /dev/null +++ b/msigdb_wp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:361d32d26c0cd5dcecb33158996bd307ea67e070b06da59462f3ba84ce53b8a1 +size 156228 diff --git a/msigdb_wp/basic/plot_41.png b/msigdb_wp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..80e72a487659f4c96dcc7ae673a5c1ca350e8632 --- /dev/null +++ b/msigdb_wp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb4b7bc115d228937e401dc9e8875d130bd34158dae86fd98ad18f58b5f22afc +size 138439 diff --git a/msigdb_wp/basic/plot_42.png b/msigdb_wp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..ff0b6503a346ff5002eb5c8bc6b3dd00266f4202 --- /dev/null +++ b/msigdb_wp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cfeda48908953d4108380ab4363649cfff35605a008ca1ae6d8f4d0e9d5b704 +size 144625 diff --git a/msigdb_wp/basic/plot_43.png b/msigdb_wp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..bcdd4ec05fe38f57508769499e5e92d81f94cfad --- /dev/null +++ b/msigdb_wp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:faa5650a81a0bd93decf8b897c592629b2805bb58992a7972c9efcc6917f4037 +size 152311 diff --git a/msigdb_wp/basic/plot_44.png b/msigdb_wp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..081adf1b887122fc3556961b42a9c1c96440ae70 --- /dev/null +++ b/msigdb_wp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:199f6bf6cae1f52ac05640574ffd5dbba8c3902b79828f12e513d146d995e6c1 +size 139706 diff --git a/msigdb_wp/basic/plot_45.png b/msigdb_wp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..7fa6b02162e9a94662624c324faa6eeccce5f87a --- /dev/null +++ b/msigdb_wp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a01b699b14d57550ef8511ff64ae2c97b025bc74a0923de46d190e17abcdae75 +size 152694 diff --git a/msigdb_wp/basic/plot_46.png b/msigdb_wp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..7600d725bba058222c99350fdcd6cc20b8def75d --- /dev/null +++ b/msigdb_wp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c244e1a90ad9a9c1979d40b93bcfe5c707f9a67db00a28e034919700d0cd8b0d +size 143407 diff --git a/msigdb_wp/basic/plot_47.png b/msigdb_wp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..6a39303666ea8d67d800905b71366e4cdf639a82 --- /dev/null +++ b/msigdb_wp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b8b2c25034b08902ab0f6a50a65c3f00e208cf70a23e8d6156ddfe2741bc7938 +size 149694 diff --git a/msigdb_wp/basic/plot_48.png b/msigdb_wp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..0dcd3419318451405e37011a52b2eecc5927ac13 --- /dev/null +++ b/msigdb_wp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af21aa80d720f155d6dc1619d5a0f877ce321be659913e418dc355e5335d1ed6 +size 136914 diff --git a/msigdb_wp/basic/plot_49.png b/msigdb_wp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..6daac8cf4537438a36fc94f5317b1c71fd86282d --- /dev/null +++ b/msigdb_wp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58364c555bcce0caa602740bbbf953c7901fddcd993c142ffdab65aadefe0a38 +size 156445 diff --git a/msigdb_wp/basic/plot_5.png b/msigdb_wp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..29e223b7232fbfad6c6cdc7b672d86e03b1323b5 --- /dev/null +++ b/msigdb_wp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:949562855a65a518483f90fff45f8dc5ecd94d222f1330939c7b0b3be1a0ebd2 +size 139783 diff --git a/msigdb_wp/basic/plot_6.png b/msigdb_wp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..68ef5d7424e9e38a11d69ab6eafe7ffe5b8e0da7 --- /dev/null +++ b/msigdb_wp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ddce41adc7a3ec2f5468538573b7c51beaeddb6ead1a4149bb266669bb599f80 +size 140387 diff --git a/msigdb_wp/basic/plot_7.png b/msigdb_wp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0a620c311cc7f5cef0eb056a76d6ec6d894c33f1 --- /dev/null +++ b/msigdb_wp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c14fdb4c1e1e8824d34be608230eade903cce37416c1f78dce727fdb4bd1e8bd +size 140811 diff --git a/msigdb_wp/basic/plot_8.png b/msigdb_wp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..8c874b9e6d30befb0373421fa207a74822cea622 --- /dev/null +++ b/msigdb_wp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6982d8d2124ba824a7752582f3f02e43f86c213e8a0318a67967f237722a3d7 +size 135409 diff --git a/msigdb_wp/basic/plot_9.png b/msigdb_wp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..448687ebf3bed3abd20c6806288eaeab25e06860 --- /dev/null +++ b/msigdb_wp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7451e975237387c646a5573a5326d14351cb328a803c0ae782ce078ca473ced0 +size 136725 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..94f111486b7636021d3ff43b8f838205e113439d --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f266971d85d46b6dce58034742c60bf3766f125a10b6e71a4c47a03d74682120 +size 117314 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a0df09f820332fc73a17a85a0ebded5f24d6565e --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Retinoblastoma gene in cancer 12 52 2.652566345942552 0.0079882427130262 13.902912621359222 46.932038834951456 0.0759370557009261 0.6359290150115153 7.276127428212639 3.8231846023107767 0.92369516627564 0.3276008399122643 0.060760732620555 0.049890992032257 0.0050680379489099 0.0002798090678235 +Adipogenesis 2 17 2.60376941883434 0.0092204766368628 3.3349514563106797 14.83980582524272 0.8116878271367471 0.4315804462997076 1.8300198278868576 1.6586249894114242 0.7850161250810769 0.3001767004428737 0.2871482614220745 0.0321616386247015 0.2599162900657007 0.6978235375659296 +Vasopressinregulated water reabsorption 5 18 2.451056522049508 0.0142437584778118 4.936893203883495 16.320388349514563 -0.0354172931004201 0.6873434085893579 3.04511355476444 1.4957129172197627 0.6574245748590921 0.275046760971588 0.145591480261755 0.0412617301526311 0.0484311287755044 0.0054583584483833 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 1 5 2.1807419499018854 0.029202508365796 1.3519417475728157 5.089805825242719 1.1785640435684182 0.2251763186974765 0.9373175506632808 1.2460395360513083 1.0621330167304954 0.239213231194253 0.0030359610091143 0.0124120710913681 0.0693365470158766 0.2179847922025966 +Il10 antiinflammatory signaling pathway 2 5 2.133703414864524 0.0328670663658194 0.9271844660194176 4.512135922330097 0.7237001498887344 0.3680126701520151 1.165665289829819 0.6171877190565659 1.0199190570019074 0.2873871151645336 0.0362999537782941 0.0024164244761899 0.0148625463558957 0.0053637976870067 +Sphingolipid pathway 5 9 2.123301946169794 0.0337285577266954 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.0967463289884207 0.1898352204968973 0.0983610682747182 0.020271757680103 +Progeriaassociated lipodystrophy 9 11 2.0674019018482093 0.038696299199314 2.5606796116504853 9.87135922330097 0.8348691672738174 0.3132697473637388 1.651332949166155 0.8732569863233294 1.0627007810416775 0.2700069969953336 0.0798652174269664 0.0124120710913681 0.0087554356838108 0.0013613651941044 +Acquired partial lipodystrophy barraquersimons syndrome 4 5 1.9935363438934808 0.0462027479337678 1.7402912621359223 4.497572815533981 0.9065154927122356 0.2548673055649036 1.4953091418597944 0.5048251951988992 1.235575791841686 0.2574096858611674 0.0318339803833352 0.0018236078239645 0.0113265963942617 0.0001735559058557 +Sphingolipid metabolism in senescence 6 12 1.9676512835218063 0.0491081747260029 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.1009190164756922 0.1975594178204269 0.1060727287920157 0.0043704316922178 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2540f694a936f024bc949a7ac794ab5032840bf1 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 607, + "title": "Average number of proteins per term", + "value": 11.820428336079077 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..09ac7ddbdb294b886b20b3bd568f98c2504da265 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bd72403b0878c74c0df4704fc49f06335ebe4142 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,256 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Retinoblastoma gene in cancer 0.4826474161609226 2.6525663459425517 0.0079882427130262 0.992313840506342 0.095075751506018 52 P16949,P04818,Q9UQE7,Q00534,P24941,P26583,P15927,O95067,O14757,P09429,Q14566,P00374 12 +Adipogenesis 0.7114155285211115 2.60376941883434 0.0092204766368628 0.9963854638690176 0.1056005531806748 17 P43490,P17096 2 +Vitamin d metabolism 0.873848771018767 2.5110161628418233 0.0120384184971744 0.9993584738013758 0.1238528818268627 3 P04062 1 +Vasopressinregulated water reabsorption 0.6686489013595919 2.451056522049508 0.0142437584778118 0.999834762697178 0.1374223897153074 18 Q9UJW0,Q96FJ2,Q13409,P17252,Q13561 5 +Bmp signaling in eyelid development 0.7587339504329658 2.3495697873061094 0.018795120437892 0.9999900427943968 0.1562827137780882 2 P27361 1 +Robo4 and vegf signaling pathways crosstalk 0.7384293819050383 2.251202124493048 0.024372738410624 0.9999996871445144 0.1849281526906099 2 P63000 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8585259637047254 2.1807419499018854 0.029202508365796 0.9999999846153425 0.2108722291619179 5 P07099 1 +Il10 antiinflammatory signaling pathway 0.8472879422332621 2.133703414864524 0.0328670663658194 0.9999999984508028 0.2267080600460503 5 P53004,P09601 2 +Sphingolipid pathway 0.764979054850591 2.123301946169794 0.0337285577266954 0.9999999990980538 0.2299893085820822 9 O15269,Q96G23,Q06136,P04062,Q9Y5P4 5 +Mapk pathway in congenital thyroid cancer 0.7764582685148997 2.0819402974415655 0.0373479233644706 0.9999999999075522 0.2361478071066011 3 P36507 1 +Progeriaassociated lipodystrophy 0.7166566614668199 2.0674019018482093 0.038696299199314 0.9999999999605186 0.2383732624795569 11 P49354,P28340,P46063,Q03252,P20700,Q13485,P02545,O75844,O60725 9 +Deregulation of rab and rab effector genes in bladder cancer 0.7607301563640781 2.0108528423764898 0.0443410026712003 0.9999999999988936 0.2621418772023447 3 P51159 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.8141063956963803 1.9935363438934808 0.0462027479337678 0.9999999999996612 0.2645761131678972 5 P20700,P49354,Q03252,O60725 4 +Sphingolipid metabolism in senescence 0.678697664723144 1.9676512835218063 0.0491081747260029 0.9999999999999468 0.2709878368971252 12 O15269,P24941,Q96G23,Q06136,P04062,P17252 6 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5314220732022896 1.9465091975579951 0.0515936041999776 0.9999999999999892 0.2726581349828815 24 P37268,Q13907,Q15125,Q15126,Q16850,Q15800,Q15392 7 +Nad metabolism sirtuins and aging 0.8160104262593046 1.942815975833996 0.052038396927263 0.9999999999999918 0.2726581349828815 4 P43490 1 +Hippo signaling regulation pathways 0.5844934969746955 1.9411787731402717 0.0522365968923126 0.9999999999999928 0.2726581349828815 18 Q13043,P35240,P54646,P54619,P63000,P17252,Q9NWH9 7 +Influence of laminopathies on wnt signaling 0.6696593176109722 1.9201020108113307 0.0548450153653305 0.9999999999999988 0.2814615458008886 12 P49354,Q00534,Q5JTV8,P02545,O60725 5 +Metabolism of spingolipids in er and golgi apparatus 0.7377538829151677 1.9061644823066992 0.056628868776932 0.9999999999999996 0.2847305001803978 3 Q10472,Q06136 2 +Transcriptional activation by nrf2 in response to phytochemicals 0.7902072929525578 1.891439658147602 0.058565678839157 1.0 0.2890192443525882 5 P09601 1 +Mirnas involved in dna damage response 0.7266253531774853 1.855115133627995 0.0635797871459042 1.0 0.3082492119001621 3 Q00534 1 +Mitochondrial complex iii assembly 0.7052503677183537 1.83781311174378 0.0660899488842601 1.0 0.3138739565082631 9 P22695,Q9NVA1,Q9UDW1 3 +Familial partial lipodystrophy fpld 0.7143685515969622 1.804250350218006 0.0711920693453687 1.0 0.3298747029972427 8 P49354,Q03252,P20700,P02545,O60725 5 +Nonsmall cell lung cancer 0.57424574371468 1.7959783231167283 0.0724979645895591 1.0 0.3333807917110788 17 Q00534,Q13043,P36507,P29373,P27361,P17252 6 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.7032709227323317 1.7473014550973296 0.0805850608280125 1.0 0.3570447585591504 3 P27361 1 +Electron transport chain oxphos system in mitochondria 0.4001158862601909 1.7376999596609386 0.0822636958437239 1.0 0.359237866022593 50 P18859,O43678,P51970,O75380,P06576,P14854,P12235,O43676,Q9UDW1,O75964,P22695,P56134,O75306 13 +Dopamine metabolism 0.6919857039346546 1.6948969551776478 0.0900949702396156 1.0 0.3742185845047474 3 P17252 1 +Sphingolipid metabolism overview 0.7306345166632447 1.6888783131218008 0.0912427520703502 1.0 0.3742185845047474 6 Q96G23,Q06136 2 +Sphingolipid metabolism integrated pathway 0.7306345166632447 1.6888783131218008 0.0912427520703502 1.0 0.3742185845047474 6 Q96G23,Q06136 2 +Striated muscle contraction pathway 0.741286428119381 1.6797451091705893 0.0930069190632645 1.0 0.3788939588684669 5 P08670,P67936 2 +Regulation of actin cytoskeleton 0.4177979891413002 1.660713586239533 0.0967709834389962 1.0 0.3915999129831382 40 Q14185,P35241,P35580,Q99570,Q13464,Q13177,P15311,P36507,P48426,Q9Y2A7,P27361,Q9UQB8,Q16512,Q96F07,Q92888,P26038,P63000,P12814 18 +Pdgf pathway 0.5727622059155366 1.6393844184382338 0.1011332246366567 1.0 0.4018530435890882 15 P19174,O15111,P27361,Q16512,P63000 5 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.7193689467465474 1.638627794474275 0.1012908001138888 1.0 0.4018530435890882 6 O15111 1 +G1 to s cell cycle control 0.4794008865470163 1.5712570401882375 0.1161229555566083 1.0 0.4317926678147492 24 P24941,Q00534,P15927,P33992,P35244,Q9UBD5,Q14566,P25205 8 +Base excision repair 0.524954182623568 1.5655992038318016 0.1174424765113348 1.0 0.4317926678147492 18 Q9UGN5,P28340,P13051,P09429,P18887,P39748,P18858,P27695,Q9NR33,P09874,Q07864,Q9Y2S7,P29372 13 +Cholesterol biosynthesis with skeletal dysplasias 0.6835347506544394 1.5644662696954237 0.1177081083058162 1.0 0.4317926678147492 7 Q16850,Q15392 2 +15q112 copy number variation syndrome 0.6618559536279065 1.5541381874933762 0.1201514579477616 1.0 0.4336303726914089 3 Q9BSJ2 1 +Cell cycle 0.3735156325692952 1.5433462618764515 0.1227467846915881 1.0 0.4344689847569136 54 Q09472,Q9UQE7,Q9UJX5,Q00534,P24941,Q9UJX4,P33992,O95067,O14757,Q14674,Q9H1A4,Q14566,Q9UJX2,Q9UBD5,P25205 15 +Ciliopathies 0.5556245581780952 1.5383540053033131 0.1239620817433015 1.0 0.4344689847569136 15 O75695,P57076,Q10713,Q01968 4 +Serotonin receptor 2 and elksrfgata4 signaling 0.7199989014533107 1.5348042288418138 0.1248319237401649 1.0 0.4344689847569136 4 P36507 1 +Serotonin receptor 467 and nr3c signaling 0.7199989014533107 1.5348042288418138 0.1248319237401649 1.0 0.4344689847569136 4 P36507 1 +Nrf2are regulation 0.6394670310618664 1.5156669590853165 0.1296035863889262 1.0 0.4344689847569136 9 P09601 1 +Cellular proteostasis 0.7143694141100073 1.5105571153139956 0.1309013271315808 1.0 0.4344689847569136 4 P61758,Q9NQP4 2 +Spinal cord injury 0.4899902967383998 1.496333188143788 0.1345668506519222 1.0 0.4409896216208561 21 P14174,P24941,P08670,P17252,P27695 5 +Supression of hmgb1 mediated inflammation by thbd 0.7105689224906236 1.4941735539114291 0.1351302629678406 1.0 0.4409896216208561 4 O15111 1 +Nonalcoholic fatty liver disease 0.3652428865655806 1.451020436748185 0.1467741695395241 1.0 0.4689048468973219 54 O43678,Q9P0J0,P51970,O75380,P54646,P14854,O43676,Q9UDW1,P22695,P54619,Q86Y39,P63000,O75306 13 +Biomarkers for pyrimidine metabolism disorders 0.6753021921282081 1.440721534535859 0.1496633685988366 1.0 0.4725365423689452 6 P04818,Q9Y606 2 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.6748455235687861 1.4386617555446275 0.1502463800283466 1.0 0.4725365423689452 6 P06753,O15111 2 +Disorders of folate metabolism and transport 0.653654230174209 1.425532254889554 0.1540034032072301 1.0 0.4771119976321781 7 P04818,P00374 2 +Mitochondrial complex i assembly model oxphos system 0.4593930080112685 1.4244983571573402 0.154302260305585 1.0 0.4771119976321781 24 Q9P0J0,P51970,O75380,O43676,Q9BQ95,O75306 6 +Met in type 1 papillary renal cell carcinoma 0.4841588282357377 1.4145445269453505 0.1572020832993594 1.0 0.4774453029011442 20 Q13177,P19174,P36507,P27361,O43815,Q16512,P63000,Q9NWH9,Q14241 9 +Endothelin pathways 0.6190355268261682 1.4144199799403103 0.1572386271095682 1.0 0.4774453029011442 9 P17252,P42892,P16615 3 +Il5 signaling pathway 0.5955130835637561 1.366337251922147 0.1718331337651233 1.0 0.5065212583312708 10 P36507,P62753 2 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.4934042098900151 1.3629148100254669 0.1729093606156184 1.0 0.5065212583312708 18 P49354,O60725 2 +Follicle stimulating hormone fsh signaling pathway 0.6220197946409106 1.3624835572106682 0.1730453298465342 1.0 0.5065212583312708 8 P17252,P27361,P42345,P62753 4 +Cholesterol biosynthesis pathway 0.5352702877956756 1.3555312215647046 0.1752483682016101 1.0 0.5065212583312708 14 P37268,Q13907,Q15126,Q16850,Q15800 5 +Constitutive androstane receptor pathway 0.6556286202440278 1.351881501938054 0.1764132259818569 1.0 0.5065212583312708 6 P08183 1 +Kisspeptinkisspeptin receptor system in the ovary 0.6555045751336469 1.351320820863135 0.1765926852131467 1.0 0.5065212583312708 6 P36507,P17252 2 +Mirna regulation of dna damage response 0.4321072532107094 1.3297330329900914 0.1836062470556503 1.0 0.5207896820690642 26 P24941,Q00534,P15927,O14757,O95067 5 +Nanoparticle triggered regulated necrosis 0.6120071684587711 1.319401451943342 0.1870349366246486 1.0 0.5216691091310552 3 Q14790,P09874 2 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.4972047923494806 1.317125290495616 0.1877966309872398 1.0 0.5216691091310552 17 P36507,O15111,P27361,Q16512,Q12959 5 +Circadian rhythm genes 0.3692232070176925 1.3115538815276198 0.1896707024053623 1.0 0.5216691091310552 46 Q09472,P43490,P04818,Q15233,Q14103,P54646,Q8WXF1 7 +Dna damage response 0.4364531150488638 1.306870420333431 0.1912567235891544 1.0 0.5216691091310552 25 P24941,Q00534,P15927,O14757,O95067 5 +Egfr tyrosine kinase inhibitor resistance 0.5055892429205608 1.3030193317526466 0.1925681617575994 1.0 0.5216691091310552 16 P36507,P42345,P62753,P27361,P17252,Q9NWH9 6 +Agerage pathway 0.4674242548290335 1.3012990118698495 0.1931561253390392 1.0 0.5216691091310552 20 P15311,O15111,P26038,P17252 4 +Insulin signaling in adipocytes diabetic condition 0.6645576053429303 1.2952111935728567 0.1952473844374642 1.0 0.5216691091310552 4 P62753 1 +Insulin signaling in adipocytes normal condition 0.6645576053429303 1.2952111935728567 0.1952473844374642 1.0 0.5216691091310552 4 P62753 1 +Kennedy pathway from sphingolipids 0.6619519374966826 1.2839279346443633 0.1991671719657148 1.0 0.5279234645554102 4 P35790,P48651 2 +Hippoyap signaling pathway 0.6596868431335454 1.2741198110506513 0.2026209583882536 1.0 0.5347431380072607 4 Q13043 1 +Interleukin11 signaling pathway 0.5077992244367487 1.2540398103526118 0.2098275357932504 1.0 0.5493468364716474 15 O15111,P62753 2 +Cannabinoid receptor signaling 0.6150965589699281 1.2454680464157712 0.2129597540605858 1.0 0.5547921489904534 7 P17252,Q8NCG7 2 +Target of rapamycin tor signaling 0.5575854431746086 1.2410501229819055 0.2145872332198459 1.0 0.5566429511301132 11 P54646,Q13907,P54619,P17252,P63000 5 +Estrogen signaling pathway 0.5956827110508973 1.235180061417864 0.2167634980865718 1.0 0.5575230649938521 8 O15111 1 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.5034015424378907 1.2278142594220172 0.2195167015346513 1.0 0.5621837052633517 15 P43490 1 +Gastrin signaling pathway 0.4079604752677704 1.2117637579416691 0.2256028251661206 1.0 0.5705871453159801 28 Q13464,O15111,P42345,P62753,P27361,Q16512,P17252,P63000,Q92993 9 +Netrinunc5b signaling pathway 0.5086911942545969 1.201022968094258 0.2297422919860938 1.0 0.5767396909116652 14 P36507,P27361,P62136,P17252,P63000 5 +Statin inhibition of cholesterol production 0.6315213279345142 1.1961595790839843 0.2316342912455122 1.0 0.5786091143457858 5 Q8WTV0,P37268 2 +Neural crest cell migration during development 0.6029361741705546 1.1886738585076564 0.2345680313620832 1.0 0.5811542654562635 7 P63000,Q13177,Q16512 3 +Allograft rejection 0.5585955441280032 1.177149365414318 0.239135894545146 1.0 0.5900629593044864 10 P08183 1 +Atr signaling 0.5804974945542563 1.1707749021134464 0.2416892685948006 1.0 0.5939489313240648 3 O14757 1 +Complement system in neuronal development and plasticity 0.536782572160792 1.131150717196586 0.25799166072203 1.0 0.6314553953962591 11 Q9NR28,Q8NB49 2 +Burn wound healing 0.5677519003859199 1.1003820289985216 0.2711657051680358 1.0 0.6557672630956086 8 P08670 1 +Onecarbon metabolism 0.489316466696625 1.0885305548942448 0.2763609553128936 1.0 0.6630478255925946 14 P04818,P00374,P34897 3 +Proximal tubule transport 0.5629807424242627 1.0774284513470465 0.2812888991626481 1.0 0.6722140228020763 8 P08183 1 +Cardiac hypertrophic response 0.4306661471367819 1.0522745785942376 0.2926735914757166 1.0 0.6874004279768964 20 P36507,O15111,P42345,P17252,P63000 5 +Pi3kakt signaling pathway 0.3495966836256265 1.0476574657244473 0.2947964509835397 1.0 0.6882363297961869 42 Q00534,P24941,P36507,O15111,P42345,P54646,P62753,P27361,Q16512,P63000,P17252,Q9NWH9 12 +Metapathway biotransformation phase i and ii 0.4244984072541879 1.0440595511772548 0.296457838444748 1.0 0.6894632487967896 21 Q7LGA3,P07099,P21964,Q86UY6,Q16850,P00390 6 +Thymic stromal lymphopoietin tslp signaling pathway 0.4928570750760662 1.0337516115178011 0.3012522982020709 1.0 0.6979394847658665 13 P36507,P42345,P62753 3 +Il7 signaling pathway 0.5670460808275637 1.0217577907962732 0.3068955513532256 1.0 0.7083102649102965 7 P36507 1 +Ferroptosis 0.3917727751183253 1.0174890867817956 0.3089208212431718 1.0 0.7091993441784312 26 P45880,P09601,P37268 3 +Male infertility 0.3832708459325223 1.0134816537606783 0.3108301548640708 1.0 0.7091993441784312 28 P08183,Q15165 2 +Erbb signaling pathway 0.4285499610814147 1.0073592341343662 0.3137621740436369 1.0 0.7091993441784312 19 Q13177,P36507,P42345,Q13555,P27361,Q16512,P17252 7 +Methionine de novo and salvage pathway 0.5365896673131935 1.005199292695308 0.3148008957011157 1.0 0.7091993441784312 9 Q13126,Q96GX9 2 +Nucleotide metabolism 0.4864560548155293 0.9979959623083928 0.3182813165615226 1.0 0.7125140619209951 13 P28340,P00374 2 +Common pathways underlying drug addiction 0.5209705369617043 0.9853149629682318 0.3244693851446927 1.0 0.7159945596209554 10 P36507,P27361,P17252 3 +Kit receptor signaling pathway 0.4531906024632546 0.983097802936918 0.325559305527815 1.0 0.7159945596209554 16 Q09472,P36507,P62753,P27361,P17252 5 +Glioblastoma signaling pathways 0.3980570823828958 0.9722700460116122 0.3309162214747023 1.0 0.7179715580207144 24 Q09472,P52701,Q00534,P49815,P19174,P24941,P36507,P27361,P17252,Q9NWH9 10 +Pancreatic adenocarcinoma pathway 0.4027025217905505 0.9652100479232344 0.3344396152328888 1.0 0.7179715580207144 23 Q00534,P36507,O15111,P42345,P27361,Q16512,P63000 7 +Thyroid stimulating hormone tsh signaling pathway 0.412513348834272 0.9616871614615 0.3362067733530343 1.0 0.7179715580207144 21 P24941,P42345,P62753,Q14344,P27361,P27695,Q9UNY4 7 +Serine metabolism 0.5535981976257102 0.9597372684502934 0.3371874614246326 1.0 0.7179715580207144 7 P04818,P00374 2 +Sterol regulatory elementbinding proteins srebp signaling 0.3562680068471978 0.9360796206149752 0.3492321949138182 1.0 0.7320517716577046 34 P37268,P25490,Q13907,P55735,P54619,Q16850,Q14534,P17252,Q8WTV0 9 +Il2 signaling pathway 0.4984513440615752 0.9302010855263704 0.3522669799637776 1.0 0.7320517716577046 11 P36507,P62753 2 +Omega3 omega6 fatty acid synthesis 0.5602682398988839 0.9231254280556874 0.3559418446973381 1.0 0.7323955923094381 6 O95864,O15254 2 +Vegfavegfr2 signaling pathway 0.2563107776069252 0.9054534844289008 0.3652251920096683 1.0 0.7453878239434041 184 P35221,Q15293,O60568,Q14241,Q15075,P49257,P31948,Q16512,P35613,Q14157,O75569,Q96CT7,Q4VCS5,Q13177,P15311,O43852,P42345,Q7Z478,P54646,P61254,Q5VU43,Q8WU90,Q96PU8,P55036,Q9UG63,Q12849,Q13464,Q00059,P19174,P06753,P00367,P36507,P51571,O00231,Q15650,Q9HCE1,P51116,P35579,P17252,Q9H299,P20338,Q9H2U1,P09429,Q02543,P62753,P27361,P62136,P55209,P63000,Q01968,O60885 51 +Hepatocyte growth factor receptor signaling 0.4803822436819687 0.8975300734536032 0.3694361334192817 1.0 0.7453878239434041 12 Q14185,P36507,Q9NWH9,Q16512 4 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.5141163554804665 0.8952227263288374 0.3706680383707681 1.0 0.7453878239434041 9 Q16512,Q13043,Q13177,P35240 4 +Il6 signaling pathway 0.4554097860925433 0.8934081663130263 0.371638631019408 1.0 0.7453878239434041 14 P36507,P63000 2 +Alpha 6 beta 4 signaling pathway 0.5017156312490028 0.888330448963263 0.3743630254715788 1.0 0.7474945936225276 10 P17252,P42345,P63000 3 +Intraflagellar transport proteins binding to dynein 0.5193487043550156 0.8696627627078796 0.3844847276664089 1.0 0.7616936940142462 8 P63167,O43237,Q13409,Q96FJ2 4 +Angiotensin ii receptor type 1 pathway 0.5638745639416145 0.8637076325923139 0.3877485196876475 1.0 0.7616936940142462 4 Q13485,P63244 2 +Fas ligand pathway and stress induction of heat shock proteins 0.4059942083864902 0.8593120275682311 0.3901683901958228 1.0 0.7639748801576273 19 Q03252,Q13177,P20700,P02545,Q16512,P09874,Q13813 7 +Micrornas in cardiomyocyte hypertrophy 0.3749568815494044 0.8442865575295785 0.3985092959328697 1.0 0.7720762566241736 25 Q13464,P46734,P36507,O15111,O75116,P42345,P27361,Q13144,P63000 9 +Energy metabolism 0.4286414056124087 0.8354341545662408 0.4034733061218951 1.0 0.7720762566241736 16 Q09472,Q15648,Q00059,P54646,Q99873,P54619 6 +Nucleotidebinding oligomerization domain nod pathway 0.4565764575832076 0.8328424913796203 0.4049335668751661 1.0 0.7720762566241736 13 Q9P0J0 1 +Nicotine effect on dopaminergic neurons 0.5386052967243233 0.8280272147754763 0.4076550876020288 1.0 0.7720762566241736 6 P17252 1 +Epo receptor signaling 0.5244207836253414 0.8268936754444705 0.4082973284618776 1.0 0.7720762566241736 7 P36507 1 +Joubert syndrome 0.4181371893560189 0.8236304756872687 0.4101495541558175 1.0 0.773170122275097 17 Q9Y4I1,O75695,Q10713,Q9UIS9,Q92993 5 +Modulators of tcr signaling and t cell activation 0.423884205210296 0.8071636500506608 0.419572205098804 1.0 0.7846789914090578 16 O95376,P19174,O15111,Q93034,Q14344,Q15366,Q9NQG5 7 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4316946655225842 0.8046501127509481 0.4210216152017914 1.0 0.7846789914090578 15 P08670,Q93034,Q13177,Q16512 4 +Phosphoinositides metabolism 0.495186178001655 0.8039328186117158 0.4214357751516 1.0 0.7846789914090578 9 Q99570,P19174,P48426,Q13614,Q01968 5 +Melanoma 0.4308526195852021 0.7997955411854255 0.423829266837511 1.0 0.7846789914090578 15 P36507,P63000,Q00534,Q16512 4 +Tcell receptor tcr signaling pathway 0.3886312873030836 0.7994818736716767 0.4240110530184036 1.0 0.7846789914090578 21 P36507,O15111,P08670,P27361,Q16512 5 +Amyotrophic lateral sclerosis als 0.482977847841938 0.7952818333627834 0.4264495786129063 1.0 0.7867929915441768 10 P36507,P07197 2 +Hedgehog signaling pathway wp4249 0.5350973619168559 0.7774731111026049 0.4368796925399938 1.0 0.8011660826941881 5 P17252,Q9Y496 2 +Dna replication 0.3429454880697321 0.7691615601951233 0.4417974069040007 1.0 0.8041749495720982 31 P28340,P24941,Q99741,P15927,O43913,P33992,P35244,P35251,P09884,P33991,Q9UBD5,Q14566,Q9Y2S7,P25205 14 +Ddx1 as a regulatory component of the drosha microprocessor 0.5408268110949547 0.7682088742337927 0.4423631021356733 1.0 0.8041749495720982 4 P49959,Q92499 2 +Alzheimers disease 0.290865568173941 0.7624208505396398 0.4458088657966921 1.0 0.8041749495720982 90 P45880,O15111,Q9H0B6,P12235,P21796,P55036,P04350,P16615,P49721 9 +Rac1pak1p38mmp2 pathway 0.4069072290686723 0.7554131581584289 0.4500011205951348 1.0 0.8041749495720982 17 P16949,P63000,Q16512,O15111 4 +Camkk2 pathway 0.4298555586123672 0.7494784950744885 0.453568855480424 1.0 0.8041749495720982 14 Q09472,P42345,P09601,O00429,P63000 5 +3q29 copy number variation syndrome 0.4293462165211514 0.7466506783645124 0.455274448941191 1.0 0.8041749495720982 14 Q12959,Q96EZ8,Q09161,P35240 4 +Small cell lung cancer 0.4290608202497241 0.7450670054323084 0.4562312140957751 1.0 0.8041749495720982 14 O15111,Q00534 2 +Alzheimers disease and mirna effects 0.2895916837465981 0.7427347920673113 0.4576422611652821 1.0 0.8041749495720982 91 P45880,O15111,Q9H0B6,P12235,P21796,P55036,P04350,P16615,P49721 9 +Thermogenesis 0.3403667023155268 0.7351975622546294 0.4622191834547455 1.0 0.8041749495720982 30 P23786,P42345,P54646,P62753,P54619,P17252,Q9Y4C1 7 +Pdgfrbeta pathway 0.4798674828006168 0.7313071525317657 0.4645915626353432 1.0 0.8041749495720982 9 P17252,P27361 2 +Tgfbeta receptor signaling in skeletal dysplasias 0.5028427954661063 0.7308275770279249 0.4648844769845017 1.0 0.8041749495720982 7 Q09472,P27361 2 +Tgfbeta receptor signaling 0.5028427954661063 0.7308275770279249 0.4648844769845017 1.0 0.8041749495720982 7 Q09472,P27361 2 +Bdnftrkb signaling 0.5024031088194041 0.7288946418604978 0.4660661126251959 1.0 0.8041749495720982 7 P42345,P19174,P49815 3 +Microtubule cytoskeleton regulation 0.3777781073559755 0.7270762365344591 0.4671792551350282 1.0 0.8041749495720982 21 P16949,P30622,Q16512,P17252,P63000,Q7KZI7 6 +Disruption of postsynaptic signaling by cnv 0.4885393078671289 0.7269668987016109 0.4672462335859884 1.0 0.8041749495720982 8 P27361,Q13557,Q13555,Q12959 4 +Extracellular vesiclemediated signaling in recipient cells 0.5228292995163343 0.7262805249003703 0.4676668158137573 1.0 0.8041749495720982 5 P42345,Q9NWH9 2 +Wnt signaling pathway 0.4171974140467269 0.7217442956484668 0.4704517029862241 1.0 0.8054485413550083 15 P17252,P42345,P63000,Q00534 4 +Tnfalpha signaling pathway 0.342050871554467 0.7174322734382216 0.4731074118433296 1.0 0.8054485413550083 29 Q9NR28,P46734,O15111,Q6GQQ9,P27361,Q16543,Q12931,Q14790,P63000 9 +Il18 signaling pathway 0.2927509511562187 0.7068643144167385 0.4796508022849224 1.0 0.8087445471859664 64 P16949,Q03252,O15111,O95067,P09601,P35613 6 +Tgfbeta signaling pathway 0.3121416366021451 0.6871222205757611 0.4920057127038819 1.0 0.8204600758550998 42 Q09472,Q9NPI6,P36507,Q96PU5,O95067,P63000 6 +Biomarkers for urea cycle disorders 0.4287847118542881 0.6838432330710239 0.4940741632791665 1.0 0.8216521016724769 2 Q14353 1 +Hippomerlin signaling dysregulation 0.3736536886845021 0.6748005720178918 0.4998024769223783 1.0 0.8221683021460261 20 Q13177,Q13043,P35240,P62136,Q16512,P17252,Q9NWH9,Q4VCS5 8 +Oxidation by cytochrome p450 0.5038278868198406 0.64860018446514 0.5165968362521733 1.0 0.838304052521169 5 Q16850,O43169 2 +Il9 signaling pathway 0.4690780603696153 0.6395949374168793 0.5224359746364833 1.0 0.838304052521169 8 P36507 1 +Nrp1triggered signaling pathways in pancreatic cancer 0.4196327526671284 0.6354602270001779 0.5251282987661021 1.0 0.838304052521169 13 P24941,P36507,Q13485,P27361,P63000,Q9NWH9 6 +Ras signaling 0.3225854079026543 0.6314596571761577 0.5277400195439632 1.0 0.838304052521169 33 Q13177,Q13043,P36507,O15111,P27361,Q16512,P63000,P17252,Q9NWH9 9 +Mecp2 and associated rett syndrome 0.3627992125092923 0.6290921998969735 0.529288696724695 1.0 0.838304052521169 21 P67809,P42345,Q9UQE7,P62753 4 +Praderwilli and angelman syndrome 0.448223197953428 0.6279831929639206 0.530014950159305 1.0 0.838304052521169 10 Q00534 1 +Folate metabolism 0.3930008370535208 0.6277803536323486 0.530147837948423 1.0 0.838304052521169 16 Q8WTV0 1 +Nucleotide excision repair in xeroderma pigmentosum 0.3180794120226492 0.6275062506731972 0.5303274401451876 1.0 0.838304052521169 35 P18074,P28340,P15927,P35244,P18887,Q86WJ1,Q92759,P19447,Q9NR33,Q9HCS7,P35251,P09874,P54725,Q07864,Q13620,Q9Y2S7 16 +Sarscov2 innate immunity evasion and cellspecific immune response 0.4056742327319735 0.6175920098122899 0.536844312910687 1.0 0.8402185969136612 14 P35613 1 +Pyrimidine metabolism and related diseases 0.4887534002232923 0.6172414510145612 0.5370754787520602 1.0 0.8402185969136612 6 P04818 1 +Monoamine transport 0.4946621817596155 0.6119470599385012 0.5405727843532171 1.0 0.8435158871527063 5 O15127,O14795 2 +Exerciseinduced circadian regulation 0.404098995837844 0.6091924466415403 0.5423968863436819 1.0 0.8441920769502946 14 Q96KR1,Q13907,Q13185,Q9Y2A7,Q96PU8 5 +Oxidative stress response 0.4854983684321863 0.6040122358302741 0.5458355072548096 1.0 0.8473712350477479 6 P09601 1 +Oxidative phosphorylation 0.3266103741551247 0.5979068579647789 0.5499020836572432 1.0 0.8493398594909584 29 P18859,O43678,P51970,O75380,P06576,O75964,P56134,P25705,Q86Y39,O75306 10 +Ranklrank signaling pathway 0.3609617545647408 0.5944936629392221 0.5521819795240481 1.0 0.8499579564594572 20 O15111,P42345,P63000,P27361 4 +Leukocyteintrinsic hippo pathway functions 0.4647684038732864 0.568161665365659 0.5699251988139362 1.0 0.8585717747135411 7 Q13043 1 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.480241960652652 0.5555357954224962 0.5785282332565573 1.0 0.8692243504622038 5 P27361,P08670 2 +Apoptosis 0.3717074983788 0.5490356117559303 0.582981010973664 1.0 0.8728073902141046 17 O15111 1 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.4434836500748313 0.5291994678667299 0.5966670857942757 1.0 0.8824098405839023 8 P36507,P27361,P42345 3 +Leptin signaling pathway 0.3169866514753351 0.5255889161212032 0.59917385946746 1.0 0.8827634288756024 29 Q13464,P36507,O15111,P42345,P54646,P62753,P27361,P63000 8 +Transcription cofactors ski and skil protein partners 0.4717938957607772 0.5232805656029184 0.600779023248774 1.0 0.8829851503922658 5 O14744 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.4009241120339905 0.493501424178365 0.6216583337860855 1.0 0.9055592122686827 12 P49815,P42345,P54646,P27361,P54619 5 +Primary focal segmental glomerulosclerosis fsgs 0.347279106257841 0.4928681516061831 0.6221057520857343 1.0 0.9055592122686827 19 Q14108 1 +Cancer immunotherapy by pd1 blockade 0.4619061846429777 0.4643379327903202 0.6424056508617781 1.0 0.9232924477483598 4 P40763,P04439,Q06124 3 +Lipid metabolism pathway 0.4026665116607881 0.460808857938934 0.6449357460383931 1.0 0.9232924477483598 11 P17252,P54619 2 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4448031647102295 0.4463492290688376 0.6553450009319977 1.0 0.9337897079007572 6 P27361,P12814,P19174 3 +Measles virus infection 0.3105088648324639 0.4382519167003262 0.6612036775896308 1.0 0.9399312231777656 27 O15111,P26038,Q00534 3 +Interactome of polycomb repressive complex 2 prc2 0.4382586381150524 0.4225601771650472 0.6726161865993292 1.0 0.9516970285915916 6 P55199 1 +Il1 signaling pathway 0.3316471607337413 0.4184880867660653 0.6755902949647856 1.0 0.9529378961909633 20 O15111,Q9BQ95 2 +Thiamine metabolic pathways 0.4459376287888059 0.4093092760935585 0.6823127089829542 1.0 0.9529378961909633 4 Q9HC21 1 +Interferon type i signaling pathways 0.3354234715171967 0.3877010046468904 0.6982373122316592 1.0 0.9610658696703336 18 Q99873,P63000,P62753 3 +Mevalonate arm of cholesterol biosynthesis pathway 0.392916426933415 0.3852324850451947 0.7000651775227591 1.0 0.9613671635821848 10 Q15126,P37268 2 +Autophagy 0.3912077914670219 0.3783724730915104 0.7051539141356884 1.0 0.9613671635821848 10 P54619,P42345,P54646 3 +Transsulfuration and onecarbon metabolism 0.3270332678252791 0.3783243928510592 0.7051896268286304 1.0 0.9613671635821848 19 P00374 1 +Urea cycle and metabolism of amino groups 0.3947398558526283 0.3637339524633928 0.7160566871095821 1.0 0.970192877400706 9 P19623,P54886,P12277,P00367 4 +B cell receptor signaling pathway 0.3203857405255398 0.3554757316077643 0.7222332226590047 1.0 0.974573660951931 20 P36507,O15111 2 +Vitamin d receptor pathway 0.3853274760459058 0.3551181677987152 0.7225010666035732 1.0 0.974573660951931 10 P08183 1 +Neural crest cell migration in cancer 0.3861873468973582 0.3317834119739568 0.7400528107879683 1.0 0.9866431379782672 9 P63000,Q13177,Q16512 3 +Orexin receptor pathway 0.3158744816941936 0.3311047139961258 0.7405653910312728 1.0 0.9866431379782672 20 Q00059,Q13595,O60313,P17096 4 +Translation factors 0.2743413956375711 0.3230046160670713 0.7466917461792977 1.0 0.9896111133860996 39 P41567,P55010,Q13144,O75153,P20042,P29692 6 +Brainderived neurotrophic factor bdnf signaling pathway 0.2650124816650928 0.3159378869524367 0.752049654009104 1.0 0.9912247761552564 48 P67809,P36507,O15111,P62753,P20042,P63000,Q12959 7 +Nucleotide excision repair 0.2922889312687848 0.3061752724386137 0.7594711986458642 1.0 0.9912247761552564 26 P18074,P28340,P15927,P35244,Q92759,P19447,Q9NR33,P35251,P54725,Q07864,Q13620,Q9Y2S7 12 +Rett syndrome causing genes 0.3299466310634328 0.3006709119188412 0.7636654518962451 1.0 0.9912247761552564 16 Q9HCS7,Q8WXH0,P51608,P27695,Q9Y4A5 5 +Signal transduction through il1r 0.3707681075544783 0.3000527329475729 0.7641369325329213 1.0 0.9912247761552564 10 O15111 1 +Oncostatin m signaling pathway 0.3114245649704263 0.296399821778275 0.7669247614162722 1.0 0.9912247761552564 19 P24941,P36507,P42345,P62753,P17252 5 +Regulatory circuits of the stat3 signaling pathway 0.3623959393660192 0.2947007448509417 0.7682224941258657 1.0 0.9912247761552564 11 P16949,P42345 2 +Oxidative damage response 0.3997010463378286 0.2935023930305284 0.7691381706245894 1.0 0.9912247761552564 6 P45985,P12004,Q12933,O95429,O95551 5 +Dual hijack model of vif in hiv infection 0.4054334347509291 0.2835761710637251 0.7767352004934474 1.0 0.9981203671114984 4 Q93034 1 +Il4 signaling pathway 0.3440354739297882 0.2814490653843375 0.7783659895865065 1.0 0.9981203671114984 13 Q09472,O15111 2 +Cell migration and invasion through p75ntr 0.3865971541051747 0.2800725616105528 0.7794218352732294 1.0 0.9981203671114984 7 P63000 1 +Mapk signaling pathway 0.2610219425467707 0.2620467186785536 0.7932854239812666 1.0 1.0 45 P16949,Q13043,P36507,O15111,Q9BQ95,P17252 6 +Tcell activation sarscov2 0.3212254238558275 0.261751772446161 0.7935128229652233 1.0 1.0 16 P19174,P36507,O15111,P42345,P27361 5 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3495504958382117 0.247921841970261 0.804194879932624 1.0 1.0 11 P17252,Q13555,Q15648 3 +Tolllike receptor signaling pathway 0.2953020539100726 0.2374311826902725 0.8123223009554947 1.0 1.0 21 P36507,O15111 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3201008670858657 0.2357919064780388 0.8135941488024079 1.0 1.0 15 P55010,P41567 2 +Fluoroacetic acid toxicity 0.3838832094560721 0.2356257874941884 0.8137230612686503 1.0 1.0 5 P51648 1 +Intracellular trafficking proteins involved in cmt neuropathy 0.3571127460235602 0.2326350617025208 0.8160447988547477 1.0 1.0 9 O60333,P50570,O95140,P20338,Q13614 5 +Thyroid hormones production and peripheral downstream signaling effects 0.3091212889195611 0.2321054164365311 0.8164561380411917 1.0 1.0 17 P17252,P42345,P62753,P49815 4 +Prolactin signaling pathway 0.2902128909981488 0.2240065879328878 0.8227521770601178 1.0 1.0 22 P36507,P42345,P62753,Q16512,P63000 5 +Fluoropyrimidine activity 0.3288927428522422 0.22334096050887 0.8232701503835611 1.0 1.0 13 P04818,P00374 2 +Mitochondrial complex iv assembly 0.3390438780807627 0.1940652766674772 0.8461247699199694 1.0 1.0 10 O43819,P14854,P14406 3 +1q211 copy number variation syndrome 0.3411436401058467 0.1850974814779657 0.8531525769655097 1.0 1.0 9 Q86WJ1,P54619 2 +Tumor suppressor activity of smarcb1 0.3086868063033123 0.1761915303177152 0.8601434745275285 1.0 1.0 14 Q969G3,Q00534 2 +Translation inhibitors in chronically activated pdgfra cells 0.2837808754920757 0.1749022651874171 0.8611564303494605 1.0 1.0 20 P36507,P17252,P42345,P62753 4 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.297570336474108 0.1665591211169251 0.8677169609175743 1.0 1.0 16 O15111 1 +Canonical and noncanonical tgfb signaling 0.2881457151388378 0.1608708518720165 0.8721951200941043 1.0 1.0 2 Q13485 1 +Head and neck squamous cell carcinoma 0.285070579458557 0.1538396158732384 0.87773619668152 1.0 1.0 18 Q00534,P49815,Q13485,P42345,P54646,P62753 6 +Aryl hydrocarbon receptor pathway wp2873 0.3472452957660608 0.1495903745308791 0.8810878027412754 1.0 1.0 5 Q09472,Q16543 2 +Photodynamic therapyinduced hif1 survival signaling 0.323334589567557 0.149519775166513 0.8811435064332582 1.0 1.0 10 P53985,Q9NWT6 2 +Mirna regulation of p53 pathway in prostate cancer 0.3115292712066809 0.140972409048175 0.8878917390297019 1.0 1.0 3 Q14790,O96017 2 +Ccl18 signaling pathway 0.3240329930226646 0.1401108770930268 0.8885723866910575 1.0 1.0 9 P08670 1 +Integrated cancer pathway 0.2841042528565461 0.1335621957067383 0.8937487797310188 1.0 1.0 17 P52701,P24941,O14757,P54132,P49959,Q14790,P53350 7 +Osteoblast differentiation and related diseases 0.3004895618729539 0.1298134765136348 0.8967140004229024 1.0 1.0 13 P17252,Q99570,P27361 3 +Onecarbon metabolism and related pathways 0.299936379016577 0.1282061001199219 0.8979858727135406 1.0 1.0 13 P00390,P04818,P35790 3 +Mbdnf and probdnf regulation of gaba neurotransmission 0.3273927089606991 0.125537803130122 0.9000977991769843 1.0 1.0 7 Q13464,P19174 2 +Glucuronidation 0.3289131827866458 0.1180310554157307 0.9060430512014216 1.0 1.0 6 P19367,Q16851,Q96G03 3 +T cell receptor and costimulatory signaling 0.3290913233918046 0.1155999983044758 0.9079695642509724 1.0 1.0 5 P17252 1 +15q133 copy number variation syndrome 0.3250672243800411 0.1076324689776087 0.9142872400775 1.0 1.0 4 P50454,Q9BXW9,Q92793 3 +Gdnfret signaling axis 0.2900238948625948 0.103653086799622 0.9174446573425796 1.0 1.0 3 Q9BW83,O94813 2 +G13 signaling pathway 0.2664518032995668 0.101538596835252 0.9191229200262104 1.0 1.0 19 Q13576,Q13464,P48426,Q92888,Q16512,P63000 6 +Nitric oxide metabolism in cystic fibrosis 0.3181530869301758 0.0992291645874497 0.9209563191337486 1.0 1.0 6 Q99873 1 +Pathways affected in adenoid cystic carcinoma 0.2604896976046558 0.0931968129726538 0.9257472062507376 1.0 1.0 22 P36507,Q09472,Q9UBU8,O14757 4 +Prion disease pathway 0.3048243780414588 0.0922072613103148 0.9265333689340912 1.0 1.0 8 Q09472,Q9UQE7 2 +Nocgmppkg mediated neuroprotection 0.3042603848569488 0.0911741067670849 0.9273542490499048 1.0 1.0 8 Q99996,Q13557,Q13555,Q15334 4 +Copper homeostasis 0.3118086696562114 0.08912502005874 0.9289825533842933 1.0 1.0 6 O75880,P25054,P98170,P49841,O43819 5 +Unfolded protein response 0.3116223483716723 0.0886371249886248 0.9293703027155836 1.0 1.0 4 Q9Y3I0,P05198,Q14790 3 +Endometrial cancer 0.2852007189934174 0.0885220808556544 0.9294617352428636 1.0 1.0 13 P35221,P04637,Q13418,P36507,Q02750,P35222,Q9UJX6,P25054,P27361,P28482,P49841,P31751 12 +Mapk cascade 0.2980593204406292 0.0840721709027142 0.9329990506933716 1.0 1.0 9 P36507,P27361 2 +Cytoplasmic ribosomal proteins 0.2305268034544142 0.083465978519459 0.93348102817918 1.0 1.0 75 P62841,P61247,P62854,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P62899,P62266,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635 22 +Chemokine signaling pathway 0.251500472994315 0.0810867181706251 0.9353729882684 1.0 1.0 25 O15111,P63000,Q16512,P27361 4 +P38 mapk signaling pathway 0.2850299401197614 0.0698766405670573 0.9442918457996328 1.0 1.0 11 P45985,Q12933,Q16539,O43318,P04792,P42224,Q13546,P63000,P60953,Q9UER7 10 +Physicochemical features and toxicityassociated pathways 0.2607592891494107 0.0698186996282842 0.9443379633460228 1.0 1.0 18 P61160,P07197,Q16512 3 +Homologous recombination 0.2915977385714265 0.069696293356384 0.9444353920824532 1.0 1.0 8 P28340,P49959,Q9Y2S7 3 +Wnt signaling 0.2627688795785572 0.0657571974598659 0.9475711339199372 1.0 1.0 17 O75116,Q13555,P17252,P63000,P67870 5 +Heart development 0.2901105467582828 0.0641340013714336 0.9488635283850716 1.0 1.0 4 Q13485,P28482,Q06124 3 +Angiogenesis 0.2883178966238339 0.0624014083298342 0.950243173462532 1.0 1.0 4 Q92793,P19174,P28482 3 +Map3k1 role in promoting and blocking gonadal determination 0.2901972504482906 0.0617960865547514 0.9507252200101526 1.0 1.0 5 P49841,Q13464,P61586,P28482 4 +Glycogen synthesis and degradation 0.2632265804148654 0.058951646935455 0.9529906212416136 1.0 1.0 16 P35573,P52789,P46976,Q16851,Q15257 5 +Embryonic stem cell pluripotency pathways 0.26188205831286 0.0555225676016442 0.9557221513327778 1.0 1.0 16 P36507,Q13485,P42345,P61160 4 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.2699037971460338 0.0471290623006137 0.962410364700486 1.0 1.0 4 P42345 1 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.2766915732102211 0.0462923611064322 0.963077227737824 1.0 1.0 7 Q09472,P51532,P26358,Q13485 4 +Ovarian infertility 0.2662085449656327 0.0445853903673766 0.9644377878775704 1.0 1.0 4 Q8WXH0,O75376,P11802 3 +Aryl hydrocarbon receptor pathway wp2586 0.2677799748654426 0.0394337503489148 0.9685445719400284 1.0 1.0 11 Q09472,P24941 2 +S1p receptor signal transduction 0.2695990424895212 0.039425840921117 0.9685508778465232 1.0 1.0 9 Q13510,Q9H0H5,P04899,P27361,P28482,Q13164,P63096,P31751 8 +Airway smooth muscle cell contraction 0.253436939629402 0.0320305283731518 0.9744477052610792 1.0 1.0 5 O75116,Q13464,P62140,P61586 4 +Genes related to primary cilium development based on crispr 0.2556565442407444 0.0221776746810476 0.9823062262342772 1.0 1.0 11 Q9Y496,Q7Z392,Q10713,Q6UVJ0 4 +Sudden infant death syndrome sids susceptibility pathways 0.228416170850377 0.016911348369779 0.9865073393724576 1.0 1.0 31 Q09472,P67809,Q01082,P51608,P12235,P42892,P17252,Q9UIS9 8 +Malignant pleural mesothelioma 0.2214423159279605 0.0086725719234372 0.9930803755014797 1.0 1.0 71 P35221,Q13177,P35240,Q13043,P24941,P25490,P42345,P36507,P54646,P09429,P62753,P27361,P54619,Q16512,Q9NWH9,P67870,Q4VCS5 17 +Breast cancer pathway 0.2293284626102611 0.0078497771203619 0.99373684835151 1.0 1.0 26 Q00534,P36507,P42345,P27361,P49959,P67870 6 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7012a916f90a9e22ce8fd2d1054f5b6e2654c9a6 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Bone morphogenic protein bmp signaling and regulation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSF2", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADH5", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG9", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APIP", "APLP2", "APMAP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "ASAH1", "ASCC3", "ASF1A", "ASNA1", "ASNS", "ATAD2", "ATG16L1", "ATG3", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "BACH1", "BAG2", "BAG4", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "C15orf39", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP6", "CASP7", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC7", "CDC73", "CDCA5", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CERS2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLIP1", "CLK2", "CLPTM1L", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COASY", "COL4A3BP", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRABP2", "CREBBP", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMD", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSG2", "DSP", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS8", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTA", "FOXRED1", "FPGS", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H4", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPP5K", "INPPL1", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT5", "KAT7", "KDM1A", "KDM1B", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF15", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LEO1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUZP1", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MAVS", "MBD1", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFN2", "MGA", "MGAT2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MLH1", "MMAB", "MOGS", "MORC3", "MORF4L1", "MOV10", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRI1", "MRPL19", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NF2", "NFAT5", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME2", "NME3", "NONO", "NOP2", "NOTCH2", "NPAT", "NPC1", "NPC2", "NR2F1", "NRP1", "NSD1", "NSDHL", "NSF", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OTUD5", "OTUD7B", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIAS4", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB21", "RAB27A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "REL", "RELA", "RETSAT", "REV1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RICTOR", "RIF1", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTKN", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARS", "SASS6", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SEC13", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLIT2", "SLTM", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORT1", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX4", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TAF6", "TALDO1", "TARDBP", "TBC1D10A", "TBC1D4", "TBCA", "TBK1", "TBL2", "TCF20", "TCP1", "TDP2", "TECR", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMED10", "TMEM43", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRMT2A", "TRRAP", "TSC2", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE3A", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNG", "UPF1", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP1", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR26", "WDR44", "WDR45", "WDR5", "WDR73", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XIAP", "XPC", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H15", "ZEB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ABCF2", "ACOX3", "ACTN1", "ACTR2", "AGL", "AKAP9", "AKT2", "ALDH18A1", "ALDH3A2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "APC", "APEX1", "APIP", "ARHGEF1", "ARIH2", "ASAH1", "ATP11C", "ATP2A2", "ATP5A1", "ATP5B", "ATP5J", "ATP5J2", "ATP5L", "BAG4", "BAIAP2", "BLM", "BLVRA", "BRD4", "BSG", "C21orf59", "CALU", "CAMK2D", "CAMK2G", "CASP8", "CBX3", "CCDC124", "CCNB2", "CDC23", "CDC37", "CDC42", "CDC6", "CDK2", "CDK4", "CDK6", "CERS2", "CHD1L", "CHEK1", "CHEK2", "CHKA", "CHUK", "CKB", "CLIP1", "CLUH", "COL4A3BP", "COMT", "COX6B1", "COX7A2", "CPT2", "CRABP2", "CREBBP", "CSNK2B", "CTNNA1", "CTNNB1", "CUL4B", "CUL5", "CYB5B", "CYFIP2", "CYP51A1", "DAGLB", "DAXX", "DCP1A", "DCTN2", "DCTN4", "DDX1", "DHCR24", "DHFR", "DHX29", "DHX36", "DIABLO", "DLG1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DYNC1I2", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECSIT", "EEA1", "EEF1D", "EIF1", "EIF2B5", "EIF2S1", "EIF2S2", "EIF5", "ELL", "ELOA", "EP300", "EPHX1", "ERCC2", "ERCC3", "ESPL1", "EZR", "FADS2", "FANCD2", "FDFT1", "FEN1", "FNTA", "FXR2", "GALNT1", "GAMT", "GBA", "GLUD1", "GNA13", "GNAI1", "GNAI2", "GRSF1", "GSK3B", "GSR", "GTF2H4", "GYG1", "HIF1AN", "HK1", "HK2", "HLA-A", "HMGA1", "HMGB1", "HMGB2", "HMOX1", "HNRNPD", "HS2ST1", "HSPB1", "ICMT", "IDI1", "IFT27", "ILK", "IQGAP2", "KAT5", "KDM3A", "KDSR", "KIF1B", "KIF3A", "KLC2", "LIG1", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARK2", "MBD1", "MCM3", "MCM4", "MCM5", "MCM6", "MCRS1", "MECP2", "MED1", "MFN2", "MIF", "MORF4L1", "MOV10", "MPG", "MRE11", "MSH6", "MSMO1", "MSN", "MTAP", "MTMR2", "MTOR", "MYH10", "MYH9", "MYO5A", "NAA40", "NAMPT", "NAP1L1", "NCBP1", "NCKAP1", "NCOR1", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "NF2", "NONO", "OCRL", "OPA1", "ORC3", "ORC5", "OTUD7B", "PAK2", "PARP1", "PARP2", "PCBP2", "PCNA", "PDE4DIP", "PFDN4", "PGM2", "PIK3R4", "PIP4K2A", "PKN1", "PLCG1", "PLK1", "PLOD3", "PMPCA", "PMVK", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE4", "PON2", "PPP1CA", "PPP1CB", "PRKAA2", "PRKAG1", "PRKCA", "PRKRA", "PRMT1", "PRMT5", "PSMB2", "PSMD11", "PSMD4", "PSPC1", "PTDSS1", "PTPA", "PTPN11", "PUS1", "QKI", "RAB27A", "RAB4A", "RAC1", "RACGAP1", "RACK1", "RAD23A", "RCN1", "RDX", "RECQL", "RFC1", "RHOA", "RIPK1", "ROCK1", "ROCK2", "RP2", "RPA2", "RPA3", "RPL10", "RPL14", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL26", "RPL27A", "RPL31", "RPL37A", "RPL8", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS23", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS7", "RPSA", "RTCB", "SASS6", "SCAMP2", "SCARB1", "SCARB2", "SCO1", "SCO2", "SEC13", "SERPINH1", "SH3BGRL3", "SHMT2", "SLC16A1", "SLC25A19", "SLC25A4", "SLIT2", "SLTM", "SMAD4", "SMARCA4", "SMARCE1", "SMC3", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SRM", "SSR4", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRN", "SYNE2", "TDP2", "TFAM", "TOR1AIP1", "TP53", "TPM3", "TPM4", "TRA2A", "TRAF2", "TRAP1", "TRAPPC11", "TRIP4", "TRRAP", "TSC2", "TTF2", "TUBB4A", "TUBGCP2", "TYMS", "UBAP2L", "UGP2", "UNC13B", "UNG", "UQCC1", "UQCR10", "UQCRC2", "VBP1", "VDAC1", "VDAC2", "VIM", "XAB2", "XIAP", "XRCC1", "YBX1", "YY1", "ZC3H15", "ZFR", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0ca7019c4e677bac42dbdbdac3f489e09a322854 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "cytoskeleton"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a17459ba4fa36c59290943bb43f3a064bb893672 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7f2893bff4a4e2d9b6d9a1ac5b8bc61932458ba7514a6e00d5ffb2b8ed9f8ad +size 188571 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..34e91136e2f7a352731cffd479e71476351b55a8 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "cytoskeleton", "1": "centrosome", "2": "er", "3": "cytoplasmic"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5ec4f7ff243b313190b793f7233555e4cea38803 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e91d05d164468439b272d5de710fa9272d87ffd63b01532bbba4f6d5d73ab8d3 +size 135743 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..cedb4b99adcc4c815f14cc7acd42f061b7e691c1 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ea7924b6ba3b20b234203c91cdbcb66447c42d0dfefc25daea9fe0288d6360b +size 140109 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..03bc945bfbe4358a3e54ada5f1fe1ba2f0d3f645 --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cf4bc9d54aabce48f7d182be01eed58e737ebad3d39ab04e3e24deb46c7ac43 +size 136119 diff --git a/opencell_localization/basic/plot_3.png b/opencell_localization/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..8d30395816324c15fdff031f7cb6cdf6683fa761 --- /dev/null +++ b/opencell_localization/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c15cc67b5188288001a034272ef8236a82064de3cc8ced155b3c66a89f33498 +size 140941 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bc9a9f2e54010ec9f22fff551e7b177b165ac1b3 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f16f50e53f9c761cc95dc80672055367cfa5247fb4c827062170767053c8d29 +size 74961 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a8bf3fd53b98b629d692f34c39b7327987321393 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +cytoskeleton 22 37 2.8618848621893176 0.0042112986311959 11.393203883495143 34.949029126213595 -0.0391404517204851 0.6651448603044662 5.600429285486291 2.507236909723882 0.7798131763877576 0.304065049870035 0.210390481437923 0.012498849387857 0.001374788533299 0.0001452325992069 +mitochondria 2 9 2.0439290036934974 0.0409605613795789 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0015706319822673 0.0065261066260236 0.003355333516566 0.0228394808772788 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b3e8dd86e89628d1cd00880f038c349eab9c456c --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.0 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2230fd5227fafbf426fa19cb71b0bcd23ae79592 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e7967811b0950efde87d2f5afafc098e0ebbaf5a --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +cytoskeleton 0.5672090222006562 2.8618848621893176 0.0042112986311959 0.0692301588781754 0.0715920767303313 37 Q05682,Q16181,P35580,Q9UJX5,Q96FJ2,Q9NVA2,Q13409,O00139,P12814,Q15019,Q9BZD4,Q13043,Q13561,P08670,Q99661,P35579,Q9UJX2,Q9BW19,O75122,P30622,O43707,P63167 22 +mitochondria 0.7482137298668305 2.0439290036934974 0.0409605613795789 0.5088434503260274 0.3481647717264209 9 P45880,P21796 2 +centrosome 0.41458191038184 1.4819558564990127 0.138352041108706 0.9204559534115202 0.7839948996160008 35 Q9BZD4,Q9H0B6,Q96FJ2,Q13409,Q10713,P17252,Q13561 7 +focal_adhesions 0.5130651936018394 0.6860973622902141 0.4926517141519608 0.9999902230058454 0.9433642029732972 5 P18206,Q13177,Q16512 3 +er 0.2683053178887287 0.4849693209969175 0.6276981078781052 0.9999999492753407 0.9433642029732972 86 Q15006,P09132,Q8WUX9,Q15125,P51572,Q9Y487,Q15392,Q16850,Q07065,O15173,P48651,Q9P2W9,Q9UM00,O96005,Q9P0I2,O00264,Q06136,Q96N66,Q96A33 19 +cytoplasmic 0.2215932865798121 0.0424622044693101 0.9661302410236408 1.0 1.0 429 Q05682,Q16181,P09132,Q13555,Q7L5D6,Q9UQB8,Q16512,P57076,Q13043,O15111,O43242,P42345,Q99816,Q99543,P53004,Q13561,P42356,P14174,P48426,P84098,Q13310,Q96EK5,Q9H7E9,Q9UJX2,Q9GZZ9,P30622,O76094,Q15126,P27361,Q96AX1,Q96D46,Q14997,Q96GA3,Q96N67,Q9H2M9,Q9NR45,Q8WUX9,Q9UHB9,Q9Y2A7,Q13409,O95235,Q15019,P46379,P61923,Q9Y5K8,Q9H2J4,P55036,P78362,Q9UKS6,Q9H0B6,O00429,P51116,Q06481,P49721,P55010,P31483,P26038,Q15075,Q96FJ2,P31948,Q9NWV4,P50579,Q13907,Q7KZI7,P24941,P36507,P17252,Q9NPI6,Q9UBF8,Q9UNF0,Q15036,P63000,Q01968,Q9UJX5,Q9H0A8,P50570,P46976,P23258,O00139,Q7Z392,P61160,Q9Y5P4,P12277,O00231,O14757,P49458,P30043,Q9BQ70,O75122,P46939,Q5JTV8,Q9C0E2,Q9H074,Q9Y295 94 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a3f054fd030c537c7266fe99d6e9a42549fa936c --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC2", "ANAPC4", "ANXA11", "AP2B1", "AP2S1", "APC", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1B", "BYSL", "C12orf57", "C1orf123", "C21orf59", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP6", "CASP7", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDS2", "CHEK1", "CHEK2", "CHM", "CHMP1A", "CHMP3", "CHMP6", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLINT1", "CLIP1", "CLK2", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COL4A3BP", "COMMD4", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP1B", "DCP2", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF2S3", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "EPS15", "ERG28", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNB1", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GPAT4", "GRB2", "GSK3B", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "IDI1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "IMP3", "INPP4A", "INPP5K", "INPPL1", "INTS14", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IRAK1", "IST1", "ITSN2", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "LAMP1", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LSM14A", "LSM14B", "LSS", "LTV1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K7", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARK2", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED17", "MED20", "MED21", "MED24", "MED25", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVD", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NDRG1", "NECAP1", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP2", "NOP53", "NOP58", "NPM1", "NPM3", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIN4", "PIP4K2A", "PIP4K2C", "PKM", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "PPM1G", "PRKACA", "PRKCA", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP5", "RELA", "RER1", "RHOA", "RHOG", "RICTOR", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPLP1", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SARS", "SBDS", "SC5D", "SCAMP2", "SCAMP4", "SCD", "SCFD1", "SCYL2", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24C", "SEC24D", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC35F2", "SLC5A6", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX9", "SPPL2A", "SPTLC1", "SPTLC2", "SQSTM1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STIP1", "STK26", "STK4", "STRN3", "STT3A", "STT3B", "STX12", "STX18", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCF25", "TCOF1", "TFRC", "TGFBRAP1", "TIA1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMEM192", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOLLIP", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM24", "TRIM28", "TRIM33", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TTK", "TUBB4B", "TUBG1", "TWISTNB", "U2AF2", "U2SURP", "UBA1", "UBA5", "UBE2M", "UBTF", "UFC1", "UGDH", "UPF1", "USP1", "USP10", "USP36", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS25", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS4A", "VRK3", "WAPL", "WASF2", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO4", "XPO5", "XPOT", "YES1", "YIPF5", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["ACTN1", "ACTN4", "ACTR2", "ANAPC4", "APLP2", "ATP6V0A2", "ATP6V1D", "BAG6", "BAIAP2", "BCAP31", "BLVRA", "BLVRB", "C1orf123", "C21orf59", "C8orf33", "CALD1", "CAMK2G", "CCDC47", "CDC23", "CDK2", "CHEK1", "CHMP7", "CHUK", "CKAP4", "CKB", "CLASP2", "CLIP1", "CLPTM1", "COL4A3BP", "COMMD4", "COPZ1", "CYP51A1", "DCP1A", "DCTN2", "DHCR24", "DNAJC2", "DNM1L", "DNM2", "DOCK7", "DRG1", "DYNC1I2", "DYNLL1", "DYNLL2", "EBP", "EEA1", "EIF5", "EMC2", "EMC3", "FXR2", "GET4", "GYG1", "IDI1", "KDSR", "KIF20A", "KIF2A", "KIF2C", "KIFBP", "KIFC1", "KLC2", "LTV1", "MAP2K2", "MAPK3", "MARK2", "MBOAT7", "METAP2", "MIF", "MSN", "MTOR", "MYH10", "MYH9", "NANS", "NCKAP1", "NMD3", "NUF2", "OCRL", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PDCL3", "PGRMC1", "PGRMC2", "PI4KA", "PI4KB", "PIP4K2A", "PKN1", "PMPCA", "PMVK", "PRKCA", "PSMB2", "PSMD11", "PSMD3", "PSMD4", "PSME4", "PTDSS1", "RAB3GAP2", "RAC1", "RPL19", "SEPT11", "SEPT2", "SEPT7", "SNX17", "SRP19", "SRP68", "SRP72", "SRP9", "SRPK2", "STIP1", "STK4", "STX18", "TCF25", "TIA1", "TMCO1", "TOR1AIP1", "TRAPPC11", "TSG101", "TUBG1", "UBA5", "UTRN", "VCL", "VDAC1", "VDAC2", "VIM", "VPS33A", "XPO4"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json b/panther_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..45a9b2fc638aa4cba757bdcb72f4485b635c5c22 --- /dev/null +++ b/panther_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "transporter", "1": "primary active transporter", "2": "membrane trafficking regulatory protein", "3": "microtubule binding motor protein"} \ No newline at end of file diff --git a/panther_protein_class/advanced/plot_0.png b/panther_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8ac72d179efcd51ac5c6100140f683dd274d7329 --- /dev/null +++ b/panther_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6d189d6c967770edc7573814ab8a36b5b8ed73a94e4f1b7cb8a15c9f6844f64 +size 207640 diff --git a/panther_protein_class/advanced/plot_1.png b/panther_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..cdec49544d922574e6d5464dc32ed879b6459cad --- /dev/null +++ b/panther_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51282072f5f0edca7e1b7aba9d9affd0a88d62bf725f65b6589e57e85f2103d0 +size 202242 diff --git a/panther_protein_class/advanced/plot_2.png b/panther_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..37becd2cd2a6863746960b20061c6b168ecf1699 --- /dev/null +++ b/panther_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e0dfff6c30fc3d09b5ddecdb29a79d41926e956ba9edaeaec73f0e63230f935 +size 207165 diff --git a/panther_protein_class/advanced/plot_3.png b/panther_protein_class/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..431494b3777c03bf6b41ca30da7c2878d9a8958e --- /dev/null +++ b/panther_protein_class/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eaba3504d609ce3b7b736e00a7e04dff3060eee48e07ae8af2bf569a1827db61 +size 197378 diff --git a/panther_protein_class/basic/idx2term.json b/panther_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d29adfe16bf735dc41976668a55977c3a2cc258e --- /dev/null +++ b/panther_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "transporter", "1": "primary active transporter", "2": "membrane trafficking regulatory protein", "3": "microtubule binding motor protein", "4": "protein modifying enzyme", "5": "ATP synthase", "6": "DNA helicase", "7": "translation initiation factor", "8": "metalloprotease", "9": "non-receptor serine/threonine protein kinase", "10": "RNA helicase", "11": "reductase", "12": "actin or actin-binding cytoskeletal protein", "13": "DNA-binding transcription factor", "14": "ribosomal protein", "15": "transferase", "16": "aminoacyl-tRNA synthetase", "17": "oxidoreductase", "18": "kinase", "19": "DNA metabolism protein", "20": "chaperone", "21": "carbohydrate kinase", "22": "scaffold/adaptor protein", "23": "ubiquitin-protein ligase", "24": "actin and actin related protein", "25": "glycosyltransferase", "26": "chaperonin", "27": "mutase"} \ No newline at end of file diff --git a/panther_protein_class/basic/plot_0.png b/panther_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..891da20edb66970a314e309bebecf243d8dab506 --- /dev/null +++ b/panther_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da61635ef62f0061bd9c8b0a737ef6f9f2c3748e07f562b75a36f61bb6dca828 +size 133552 diff --git a/panther_protein_class/basic/plot_1.png b/panther_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6156541a3ab2e4832d90a6217fe23ea8e488d227 --- /dev/null +++ b/panther_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:201bfec947b9eb0b3bc5b70810f8ce611075074500cc8e3a663f149f8b02a174 +size 139546 diff --git a/panther_protein_class/basic/plot_10.png b/panther_protein_class/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..3d84f0e7985b29d0b39b41c61aba0f5048d09e7c --- /dev/null +++ b/panther_protein_class/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5c8fe7e4041aa83b0cbce031f2dfdccf9ac85bcfd0d6d4bd48a56f09e4bfb60 +size 139225 diff --git a/panther_protein_class/basic/plot_11.png b/panther_protein_class/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..85c837e3f81d87ed8c3ddcc927e1e0495f688c72 --- /dev/null +++ b/panther_protein_class/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6d9aabca986f29ac1b7051c093c135c7ed62411884fa71618b0c52e7b45f8e9 +size 134569 diff --git a/panther_protein_class/basic/plot_12.png b/panther_protein_class/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..6a76e22523e1aaf31fbb977b01a0bbfbf51ee773 --- /dev/null +++ b/panther_protein_class/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45e2a4e1020b28cf794db8b1236d0055d8bb1f3bab8f59dc588f5603b7c421aa +size 148425 diff --git a/panther_protein_class/basic/plot_13.png b/panther_protein_class/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..734b12bc5ca70a754644f821d5f4401cd19cbfb5 --- /dev/null +++ b/panther_protein_class/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dc75f08c19c07105c8d782a06b76c394caacb88ab4c22ff7fd7ec9303f8ce24 +size 151262 diff --git a/panther_protein_class/basic/plot_14.png b/panther_protein_class/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..5d6b834ae59820ea50c9bcd2971a8d3f6aacb138 --- /dev/null +++ b/panther_protein_class/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00c11fe270a6a0517e5701c38c6ede62e4ae1e7690da1dd984f6ef9a821faf3a +size 145611 diff --git a/panther_protein_class/basic/plot_15.png b/panther_protein_class/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..d7dc6880b7b487f9eed77468f9fdbe3a6bf2d365 --- /dev/null +++ b/panther_protein_class/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2affb70cc019b1f597b060496da060189c0beb892b6e6bf5fd5d6ab201769aa4 +size 142771 diff --git a/panther_protein_class/basic/plot_16.png b/panther_protein_class/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..78f2637bdf5476e30fa8b830f247ac5ad3dc7439 --- /dev/null +++ b/panther_protein_class/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5458e8c5d8f3ba7ff24429296ad6eeda36ac0a9beb84a78a95dc9c6a3cb954b2 +size 152591 diff --git a/panther_protein_class/basic/plot_17.png b/panther_protein_class/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..3027527c170c6f395d01ff4efeeb26b5b9587f66 --- /dev/null +++ b/panther_protein_class/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f16a8068fa5995a7a48b6ca1e330a8b489d2f730e0c9fa70c9235d128618413 +size 147032 diff --git a/panther_protein_class/basic/plot_18.png b/panther_protein_class/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..641c7a73e8a84697d27a94fa1353262fd0b11dc1 --- /dev/null +++ b/panther_protein_class/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15ffd7d7f507d79e4d3f058e6aa2441e6c2b90044a4d6f59f6f4e733b6362cb4 +size 144365 diff --git a/panther_protein_class/basic/plot_19.png b/panther_protein_class/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..d18384358070c5957b05537467f5c5e0ec2f034c --- /dev/null +++ b/panther_protein_class/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20ef26360ee2f9bc2c1a81be1b3b893077ad86b2e3a37b3c05a82455c78d15b4 +size 148727 diff --git a/panther_protein_class/basic/plot_2.png b/panther_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e399d4355f423ce8b3fcb93c16e1aee8919bcef3 --- /dev/null +++ b/panther_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9daf6d1db087fdd0d80267bf3cce664f1d8ef0df18a24296c04be34b4474081b +size 141365 diff --git a/panther_protein_class/basic/plot_20.png b/panther_protein_class/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..5eaca197bdab3be8a4806cc74707f2e034aa6e6d --- /dev/null +++ b/panther_protein_class/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:25efa0692416749a2b0bb239920b799e3a09069525306420abd7190c1b73080c +size 141610 diff --git a/panther_protein_class/basic/plot_21.png b/panther_protein_class/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..2591c724d50a3474db661e469b9c7f56edbed657 --- /dev/null +++ b/panther_protein_class/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a8cc6478dfbac05e03c462620728d22e72b9bcd3538c1ee7265c63a89355098 +size 139428 diff --git a/panther_protein_class/basic/plot_22.png b/panther_protein_class/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..c73c77c85ebe249eea9388b59e6d4949257509f7 --- /dev/null +++ b/panther_protein_class/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58e0b207f152873d5595a1b355497aff4d1b5254f4c3047c7bef769bf681364d +size 148917 diff --git a/panther_protein_class/basic/plot_23.png b/panther_protein_class/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..8c3ba4f8682e49260aa5549e2147fe5ef6344c9f --- /dev/null +++ b/panther_protein_class/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a8b5e599775cd2447220f746b05f1cf88b99257cbe6162d0d646ae219de77d9 +size 148768 diff --git a/panther_protein_class/basic/plot_24.png b/panther_protein_class/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..282ef8acaea1de2ff2f8528f09660fd512fe0788 --- /dev/null +++ b/panther_protein_class/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86718e3c702d282bf32aac2e08f0ffd2f6334f23864b0027b40f1f889c6817c7 +size 146736 diff --git a/panther_protein_class/basic/plot_25.png b/panther_protein_class/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..285558eb1027385cabb11141512a4cf6c91967ec --- /dev/null +++ b/panther_protein_class/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a1d78ba83339972db6302dca4a266ff11e03f20b5cb531fe1b4d05536035b9d +size 148807 diff --git a/panther_protein_class/basic/plot_26.png b/panther_protein_class/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..fe82b44ecaac591894badcaf38a8f8ffe0c8a4aa --- /dev/null +++ b/panther_protein_class/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0c56006370d01a2d3c96c4012ca584d796210d29a75ec1e69b59a42a0bbabbe +size 140915 diff --git a/panther_protein_class/basic/plot_27.png b/panther_protein_class/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..d5085e1ee26a58e18a8ce45823d6d77ee29487d4 --- /dev/null +++ b/panther_protein_class/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b87be48c662dcabb7987ec215b30b807f2d097d73b5ab017e1b365bf1bdc902d +size 137423 diff --git a/panther_protein_class/basic/plot_3.png b/panther_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..ce1cd89ee254f3251ca9a2c7afdce4873e396fbe --- /dev/null +++ b/panther_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e52c414c3721abf0e7233c3c16123ed8519c34dcd40a5d0ba107baedf656ece +size 134513 diff --git a/panther_protein_class/basic/plot_4.png b/panther_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..c1797ca597bf284525e70b00874982f4b62a4c52 --- /dev/null +++ b/panther_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a8a57b281e7909f0e8a28257a5361ccf8b394e2069a6d2ed4c51cc989dc3845 +size 132006 diff --git a/panther_protein_class/basic/plot_5.png b/panther_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..20bad8df309da481c144d88cd0baf4fa51a2da01 --- /dev/null +++ b/panther_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9c828778faf606f285add4a685c5cf61372adfac4c393b44cbfbf238548b54c +size 130705 diff --git a/panther_protein_class/basic/plot_6.png b/panther_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..9adea9bfee4afdef077344207625e41058223c78 --- /dev/null +++ b/panther_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2a0c42f7431a0ea896260a048965f09dbe8afb11b243a9d328c61ef02e7b392 +size 118803 diff --git a/panther_protein_class/basic/plot_7.png b/panther_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1edff90ffac7df2c126ba930bfd2cd7d3a2cf8dc --- /dev/null +++ b/panther_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c0e00d8e70927b120811c3570102d1fd6c2eaba761a125b222594fbf9ebfc93 +size 143499 diff --git a/panther_protein_class/basic/plot_8.png b/panther_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..aecc3ace4fff59135d7e8c98d66fe4db3a24466a --- /dev/null +++ b/panther_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44119a6f867b361e840594b2dd5ed9ee6d2978df9e0af9d8ace0df3a45282b9f +size 142921 diff --git a/panther_protein_class/basic/plot_9.png b/panther_protein_class/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ea1bf94d42e094650e36780a4f6a752ab04b9d20 --- /dev/null +++ b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b3f65c2c15151a6efc591cd3ce5ece72e6e3ae58af6df705d5212d4a25ca1ff3 +size 150398 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7246b244f3419885398be896d0a1f14caa3875cc --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f1579456303fd3a56f8cdf03b39fb14bca58eeae0a1bfee9225cb8b6e90753d +size 88168 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..451f57bee5eab976c4023c04d58959265be35f33 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +transporter 10 54 3.269001392596014 0.0010792777034525 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 0.0020080698640604 0.00084873619422 0.0001217230774778 0.0016164231636662 +primary active transporter 8 21 2.727354448657544 0.0063844417338418 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 0.0330078204264017 0.1174994317391053 0.0168986737095617 0.0029211533393603 +oxygenase 3 5 2.206853126655363 0.0273243220512224 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0053811669607165 0.0215793786244467 0.0195244436529747 0.0272826327042602 +membrane trafficking regulatory protein 5 22 2.191445762338601 0.0284195505863129 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.001829927485586 0.0138699265420804 0.0390247080582918 0.0138300064936424 +microtubule binding motor protein 10 22 2.02660948889728 0.0427023653784126 6.228155339805825 19.66747572815534 0.0710032026502337 0.6547182810354253 3.200634569233492 2.6001513094308857 0.7699400596004022 0.2979983415743604 0.2067156970668985 0.0817843887075946 0.1203869764331773 0.2257163036668415 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9183f2aada1c178b54f7a1efb503df06dc09d7a1 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 158, + "title": "Average number of proteins per term", + "value": 14.49367088607595 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..89b20811ac90f72d1e5de2f177c663d780724a45 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..43e84464415e2474ef2ff87aa4f43d3d00e37edc --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,56 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.5387717714211914 3.269001392596014 0.0010792777034525 0.1568563783495846 0.0209484368183386 54 O60830,Q99595,O43615,P53007,Q9H2D1,Q567V2,Q9HD45,Q92544,P53985,Q00169 10 +voltage-gated ion channel 0.9810155804011452 2.960548465354143 0.0030709180026029 0.3848884131697819 0.0364379964071755 3 P21796 1 +primary active transporter 0.6785970903183121 2.7273544486575436 0.0063844417338418 0.6364998946993001 0.0616951019740246 21 O60888,Q8N4H5,P09132,P16615,O75381,Q9NS69,Q8NB49,Q6P4A7 8 +amino acid kinase 0.8008360704688 2.550248434660536 0.0107646180325795 0.8191396626033721 0.0773095295067077 2 P12277 1 +DNA glycosylase 0.7527620185129895 2.3207446652915595 0.0203006285566704 0.9608558337386645 0.1145535468554976 2 P13051 1 +oxygenase 0.8647874109902347 2.206853126655363 0.0273243220512224 0.987441062400352 0.1392658994868759 5 Q16850,P09601,P30519 3 +membrane trafficking regulatory protein 0.5849371564217125 2.191445762338601 0.0284195505863129 0.9894889716003872 0.1403215310199202 22 P24390,O43760,Q15075,Q14108,Q8WTV0 5 +microtubule binding motor protein 0.5603070269373275 2.0266094888972797 0.0427023653784126 0.998987433023011 0.1874159369385888 22 Q9UJW0,Q9Y496,P33176,Q9H0B6,Q99661,O00139,Q9BW19,O95235,Q13561,Q9NS87 10 +mitochondrial carrier protein 0.764477363165107 1.9349925974976545 0.0529912040755458 0.999816374064186 0.2214924412463284 7 Q9BSK2,Q70HW3 2 +actin binding motor protein 0.7639743277109499 1.9327229700527928 0.0532703339706359 0.9998247307217284 0.2214924412463284 7 P06753,P67936 2 +protein modifying enzyme 0.54329401155639 1.911246996634716 0.0559728469527864 0.99988842964838 0.2228152715826506 22 O60568,O75718,P50897,Q99873,P33908,Q6NYC1,O60725 7 +ATP synthase 0.5291201688354338 1.7630324108340665 0.0778950234389088 0.9999972754309946 0.2734980822966133 21 P18859,Q6IN85,P06576,Q9Y5K8,Q93050,O75964,Q9Y487 7 +replication origin binding protein 0.7016129032257971 1.739614173232332 0.081926788850271 0.9999986366235508 0.2814007095291919 3 Q9UBD5,Q99741 2 +DNA ligase 0.6195879366975218 1.656203106594698 0.0976806943474828 0.9999999115048614 0.3026186217039664 2 P18858 1 +protein-binding activity modulator 0.7306718098210438 1.633387888214992 0.1023874427303472 0.9999999612698398 0.3111003067575936 5 Q9UNN8,O14737,Q9UNZ2 3 +lyase 0.5941004582749887 1.6020441245440942 0.1091458524677115 0.999999988266062 0.3187169836594324 13 O95900,Q9BU89,P53701,Q9UHG3 4 +kinase modulator 0.7056551080331628 1.5236411559686325 0.1275983763186392 0.9999999995702642 0.3482714008958653 5 P54619,P67870 2 +DNA helicase 0.5935258947272393 1.512404439921094 0.1304310061164342 0.9999999997429372 0.3482714008958653 12 P18074,P46063,P54132,Q96RR1,P19447 5 +oxidase 0.5387418857492006 1.5052688809966457 0.1322549623655184 0.9999999998155163 0.3482714008958653 16 P36551,P14854 2 +viral or transposable element protein 0.639720080883227 1.4500971502796638 0.1470314296903589 0.9999999999877702 0.3746929982431729 3 Q9H2J4 1 +GTPase-activating protein 0.4990250453216691 1.399147762275677 0.1617686775341513 0.9999999999992212 0.3993664226624361 18 Q13017,O75695,Q66K14,Q4KMP7 4 +cytoskeletal protein 0.6616603686413556 1.379138418435791 0.1678520805765972 0.9999999999997536 0.4013533150536093 6 Q9P0V9,Q16181,Q15019,Q14141 4 +translation initiation factor 0.363599578722995 1.2971952086287188 0.1945640289073082 0.9999999999999986 0.4276446957778371 48 P46199,Q9ULC4,P41567,P55010,Q13144,O75153,P31483,P20042 8 +metalloprotease 0.4267057458952803 1.2878966040218398 0.197781957795561 0.9999999999999992 0.4276446957778371 26 P53582,P22695,Q96TA2,O95630,Q10713 5 +non-receptor serine/threonine protein kinase 0.3409746791053361 1.2807278105437263 0.200289287895949 0.9999999999999996 0.4276446957778371 64 Q7KZI7,P78362,Q13177,Q13043,Q00534,O15111,P24941,P42345,P36507,Q13555,Q6P3W7,P54646,O14757,P27361,Q16512,P17252,Q9Y4A5 17 +calmodulin-related 0.5451839020454026 1.2490017956613897 0.2116644170788562 1.0 0.4459063719794571 12 P80303,O43852,Q14257,Q15293 4 +primase 0.5043296506419908 1.0605141641300448 0.2889107496182248 1.0 0.5812955811849165 2 P49643 1 +tubulin 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.6140726934572057 7 P04350 1 +RNA helicase 0.4644456579336568 0.945065518888895 0.3446254276351954 1.0 0.62587146628001 14 Q9H2U1,Q7Z478,Q9UL03,O60231,Q14147 5 +esterase 0.5329312737001655 0.9338070319251784 0.3504034415496986 1.0 0.6291334518733225 8 Q9NUJ1 1 +reductase 0.3397974191026378 0.7306168724666424 0.4650132032440175 1.0 0.7796382058652656 30 Q9H7Z7,Q9UDW1,Q06136,P30043,P00390,P00374,Q15392 7 +transfer/carrier protein 0.4581746352146867 0.7244821085233142 0.468769807324052 1.0 0.7796382058652656 11 O14828,O15127,Q9Y5P4,P12235 4 +actin or actin-binding cytoskeletal protein 0.3713072102892018 0.6598055403642615 0.5093786274670258 1.0 0.8285031078425954 20 P35241,P35240,P15311,Q9UKS6,P59998,P26038 6 +DNA-binding transcription factor 0.3198561679024111 0.4051748804402249 0.6853489679720599 1.0 0.9591816108297372 23 Q86YP4,Q13485,P20290,Q9NR33,Q01664,Q9UHB7,Q8IVW6,Q8WXI9 8 +acetyltransferase 0.3918581867574285 0.3809783807241613 0.703219290654348 1.0 0.9591816108297372 10 Q9BXJ9,Q96N66 2 +ribosomal protein 0.2600533950629947 0.3662145288728531 0.714205001650509 1.0 0.9591816108297372 122 Q92665,Q8N5C6,P62841,Q9H2W6,Q9P015,P61254,Q16540,P62081,P46778,P50914,P82933,P08865,P25398,P84098,P62917,Q96A35,P62899,P55769,P46782,Q02543,P62753,P15880,Q7Z7H8,Q92552,P27635,Q9Y3D3 26 +transferase 0.2886602426897397 0.3592134266476706 0.7194354330294301 1.0 0.9591816108297372 32 Q8NFF5,P43490,Q7LGA3,P37268,P48651,P19623,O75390,Q2TAA5 8 +translational protein 0.3523439832785862 0.3552242580334737 0.7224215929667008 1.0 0.9591816108297372 2 Q12904 1 +methyltransferase 0.3365063705998948 0.3311652814815516 0.740519643324796 1.0 0.9595425354967568 16 Q9BV86,Q86TU7,P04818,P34897 4 +aminoacyl-tRNA synthetase 0.2794592927517415 0.3124661276563298 0.7546863014760306 1.0 0.9595425354967568 34 P54136,P49591,Q9HA77,Q9Y285,P49589,A2RTX5,P41250,P23381,P49590,Q5T160,P47897,Q9BW92 12 +transcription cofactor 0.3330138867910415 0.2685507618177672 0.78827540700803 1.0 0.9675471409290036 14 O00625 1 +oxidoreductase 0.2545827546515462 0.2470694266588824 0.8048544943427183 1.0 0.9707405351614464 50 P48163,O43678,P51970,P16435,P35754,O75380,Q9Y6M9,O15254,O95825,O43676,Q13630,Q9Y6N5,Q86Y39,P30044,O43169,O75306 16 +kinase 0.2873669784085358 0.2227894897743889 0.8236993483874417 1.0 0.985943159433453 23 P42356,P48426,Q9UBF8,Q15126,P35790 5 +DNA metabolism protein 0.2554873835838464 0.2119999652643976 0.8321070614215764 1.0 0.9885181631925494 43 P52701,Q04837,Q8IYB8,P25205,P28340,P09874,Q8IWS0,P33991,Q14566,Q92547,P42285,P33992,Q9UBZ9,P18887,P35251,P09884,P20585,P51608,Q8WVB6 19 +chaperone 0.2424114996224934 0.1801330825511933 0.8570480912674823 1.0 1.0 67 P46379,Q99471,Q96KC8,Q96EY1,Q15006,Q9UBS4,P30622,Q9NVH1,Q9NVA1,P61758,Q86Y56,Q8IXB1,P30533,Q99543,O75937,Q13427,O75607,Q9NVM6 18 +carbohydrate kinase 0.3437967115097232 0.1475314268622539 0.8827125760696395 1.0 1.0 6 P00558,P51570,P17858,Q01813,P08237 5 +scaffold/adaptor protein 0.2376180397047257 0.1384827305593721 0.8898589171280076 1.0 1.0 86 Q96PV6,Q9UNH7,P07602,Q9UQB8,P35613,Q9Y2W6,Q9BQ95,Q12959 8 +ubiquitin-protein ligase 0.2350408329189713 0.1202334522717115 0.9042982189004044 1.0 1.0 63 Q9Y263,O95376,Q8TDB6,Q96PU5,O94874,Q5T4S7,Q93034,P14373,O15344,Q99816,Q9H1A4,Q9UJX2,Q9GZZ9,Q9Y4J8 14 +histone modifying enzyme 0.2768934262898956 0.1089057498919878 0.9132772460202232 1.0 1.0 17 Q9NWY4,Q09472,Q92993 3 +actin and actin related protein 0.318983557548591 0.1006053777387293 0.9198637275514588 1.0 1.0 6 O96019,P61160,P61163,P61158,Q9GZN1 5 +G-protein modulator 0.275667659749469 0.0447422141558189 0.964312785341316 1.0 1.0 6 Q9H2M9,P11274 2 +RNA methyltransferase 0.2539437889883894 0.0364866600767216 0.9708943153444314 1.0 1.0 16 Q969Y2,Q96FX7 2 +glycosyltransferase 0.2382688107434403 0.0314761712647302 0.9748897953029948 1.0 1.0 25 Q10472,P04844,Q9NRG1,Q9Y673,P46976,Q9H6U8 6 +chaperonin 0.262196947021852 0.0301487786734152 0.9759483986371924 1.0 1.0 10 P49368,P50991,P78371,Q99832,P17987,P61604,P50990,P40227,O75347 9 +mutase 0.2497009569378004 0.0222950731412632 0.982212578970566 1.0 1.0 7 P18669,Q96HS1,P22033,Q6PCE3,Q96G03,O95394 6 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b3f7297eb9cbec2059d25159457a68e2bb43212f --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGPAT1", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APIP", "APLP2", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BCR", "BDH2", "BLM", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK2", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COASY", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EP300", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GFM2", "GFPT1", "GGH", "GINS1", "GINS2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIC2", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INPP5K", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LENG8", "LEO1", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLH1", "MLLT1", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCKIPSD", "NCOA5", "NCOR1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NF1", "NF2", "NFAT5", "NHP2", "NIP7", "NIPBL", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPM3", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OXCT1", "OXNAD1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTCD1", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRN3", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTKN", "S100A10", "S100A11", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHPK", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC39A14", "SLC4A1AP", "SLC4A7", "SLC5A6", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRBD1", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT20H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAB1", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM115", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAF2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM27", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNG", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WARS", "WARS2", "WASF2", "WASHC2A", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR74", "WDR82", "WDR92", "WIZ", "WNK1", "WRNIP1", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZEB1", "ZFP91", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF326", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["ABHD10", "ACOX3", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "AFF4", "AIMP1", "ALG11", "ALG5", "ALG9", "ANAPC1", "ARHGAP5", "ARID3B", "ARIH2", "ARPC4", "ATP11C", "ATP2A2", "ATP5B", "ATP5J", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAG6", "BAIAP2", "BCR", "BLM", "BLVRB", "BSG", "BTF3", "CALU", "CAMK2G", "CARS", "CARS2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CDC23", "CDC6", "CDK2", "CDK6", "CHEK1", "CHKA", "CHTF18", "CHUK", "CKB", "CLIP1", "CLUH", "COL4A3BP", "COX6B1", "CPOX", "CRTAP", "CRYZL1", "CS", "CSNK2B", "CUL5", "CUTA", "CYB5B", "CYP51A1", "DCTN2", "DCTN4", "DHCR24", "DHFR", "DHX16", "DHX29", "DHX34", "DHX36", "DLG1", "DNAAF5", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC17", "DNAJC2", "DNAJC8", "DOHH", "DTNA", "DTX3L", "ECSIT", "EEA1", "EIF1", "EIF2B5", "EIF2S2", "EIF5", "EMC2", "EP300", "ERCC2", "ERCC3", "EZR", "FARSA", "FDFT1", "FLAD1", "GALK1", "GALNT1", "GARS", "GATAD2A", "GATAD2B", "GLRX", "GSR", "GTPBP3", "GYG1", "HARS2", "HCCS", "HMOX1", "HMOX2", "HPF1", "HS2ST1", "HSPE1", "ICMT", "INTS6", "JMJD6", "KAT5", "KDELR1", "KDSR", "KIF15", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "KLC2", "LENG8", "LIG1", "LRPAP1", "MAN1A1", "MAP2K2", "MAPK3", "MARK2", "MBOAT7", "MCM3", "MCM4", "MCM5", "MCM6", "MCTS1", "ME1", "MECP2", "METAP1", "MID1", "MPV17L2", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSH3", "MSH6", "MSN", "MTIF2", "MTOR", "MUT", "NAA15", "NAMPT", "NDUFA11", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS6", "NEDD4L", "NF2", "NPM3", "NSFL1C", "NTMT1", "NUCB2", "ORC3", "PACSIN3", "PAK2", "PARP1", "PCYOX1", "PDCD5", "PDCL3", "PEX14", "PFDN5", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGK1", "PGM2", "PGM2L1", "PGM3", "PHF6", "PI4KA", "PI4KB", "PIP4K2A", "PIR", "PITPNA", "PKN1", "PLAA", "PLOD3", "PMPCA", "PMVK", "POLA1", "POLD1", "POLE4", "POR", "PPIG", "PPP4R3A", "PPT1", "PRDX5", "PRIM2", "PRKAA2", "PRKAG1", "PRKCA", "PRMT1", "PROCR", "PRTFDC1", "PSAP", "PTDSS1", "PTGES2", "QARS", "RAB3GAP2", "RARS", "RARS2", "RCN1", "RCN2", "RDX", "RECQL", "REV1", "RFC1", "RP2", "RPL10", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL26", "RPL31", "RPL8", "RPN2", "RPS12", "RPS15", "RPS2", "RPS5", "RPS6", "RPS7", "RPSA", "SARS", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCYL2", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SETD3", "SFXN4", "SHMT2", "SKIV2L2", "SLC16A1", "SLC25A1", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SMAD4", "SNU13", "SNX6", "SQOR", "SRBD1", "SRM", "SRP19", "SRPK2", "SSBP1", "STAMBP", "STK4", "SUPV3L1", "SYNGR2", "TARS2", "TARSL2", "TBC1D10B", "TBC1D9B", "TBCA", "TCP1", "TDRKH", "TFAP4", "TIA1", "TIMM17A", "TIMM17B", "TIMM44", "TM9SF3", "TM9SF4", "TOMM22", "TOMM5", "TOPBP1", "TPM3", "TPM4", "TRIM27", "TRMT61A", "TRRAP", "TRUB2", "TSG101", "TSTA3", "TUBB4A", "TWNK", "TYMS", "UBA5", "UBR4", "UFL1", "UNG", "UQCC1", "UQCR10", "UQCRC2", "VBP1", "VDAC1", "WARS", "XRCC1", "YME1L1"]} \ No newline at end of file diff --git a/pharos_dto/advanced/idx2term.json b/pharos_dto/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..18678af2f105db8ba8235551d1b3a1da9a99dfc6 --- /dev/null +++ b/pharos_dto/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "SLC25 family of mitochondrial transporters", "1": "Receptor", "2": "Transporter", "3": "SLC superfamily of solute carriers"} \ No newline at end of file diff --git a/pharos_dto/advanced/plot_0.png b/pharos_dto/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d9f7c23a0982a138383d926e929b3820744b1544 --- /dev/null +++ b/pharos_dto/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:789b07284176dd069b0e683157295c05be2d6635fe8c76eafa6e57f02d54135a +size 203230 diff --git a/pharos_dto/advanced/plot_1.png b/pharos_dto/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..272f214ae98ecc26b696a13b4423491d1343b703 --- /dev/null +++ b/pharos_dto/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ccac76a4023150147b12895fa321d4d861af95fcbf89c939f854b4abca81f1b +size 211130 diff --git a/pharos_dto/advanced/plot_2.png b/pharos_dto/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d4286fff52ad15e27d29fe45401626562b8e5412 --- /dev/null +++ b/pharos_dto/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:caf8a686726be6932df40e22f355d932137fe7172f204ad8827c105d79d2b61c +size 227602 diff --git a/pharos_dto/advanced/plot_3.png b/pharos_dto/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6ae5ebcd10c2877127a836bf6ba17817982f76ca --- /dev/null +++ b/pharos_dto/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8729fbb9194bb1a31aab80a369ff8416431fdad44f21d1cc03435a49fd07d871 +size 212305 diff --git a/pharos_dto/basic/idx2term.json b/pharos_dto/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bebd2e1260a1f7e137bef5b018e9ae3799a5d96a --- /dev/null +++ b/pharos_dto/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "SLC25 family of mitochondrial transporters", "1": "Receptor", "2": "Transporter", "3": "SLC superfamily of solute carriers", "4": "Membrane trafficking regulatory protein", "5": "Helicase", "6": "Microtubule binding motor protein", "7": "F-type and V-type ATPases", "8": "Metalloprotease", "9": "Actin family cytoskeletal protein", "10": "Methyltransferase", "11": "Protein kinase", "12": "Cellular structure", "13": "Chromatin/chromatin-binding protein", "14": "Small GTPase", "15": "DNA binding protein", "16": "Ribosomal protein", "17": "Kinase", "18": "Microtubule family cytoskeletal protein", "19": "mRNA splicing factor", "20": "Glycosyltransferase", "21": "Actin and actin related protein", "22": "Protein phosphatase", "23": "G-protein", "24": "Chaperonin", "25": "Non-protein kinase"} \ No newline at end of file diff --git a/pharos_dto/basic/plot_0.png b/pharos_dto/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..55fe580b3eab8d5c5827e28bc564918568379e31 --- /dev/null +++ b/pharos_dto/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d94accf537c4d1acc6abc8d3cdd76a3f4c5a874c38d372cec518c87d3e0e1ec8 +size 145936 diff --git a/pharos_dto/basic/plot_1.png b/pharos_dto/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..43894e2a5e41ee591f8db14470c0ea583d33e60c --- /dev/null +++ b/pharos_dto/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:49fcb886a87d9bc527c36d95d977664418522069c0a96984c391917087ea3c84 +size 135368 diff --git a/pharos_dto/basic/plot_10.png b/pharos_dto/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..8199393f0b9ce631d6d9014eba40a8bd05aa6351 --- /dev/null +++ b/pharos_dto/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5b5b2d251b364f7f6072672724d8f28c2270712778577d1589d77f4de885a0b +size 136173 diff --git a/pharos_dto/basic/plot_11.png b/pharos_dto/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..7014b9fe9808b64d0bece7ac3e7ed2f42dbec33b --- /dev/null +++ b/pharos_dto/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9246a0cbefe5968bf8f847a9e4afb936fcebbbf9e0620201f720f590bc0d09d +size 145693 diff --git a/pharos_dto/basic/plot_12.png b/pharos_dto/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..16da3013c6b239a3606b6f186b61aacf27d1a8e9 --- /dev/null +++ b/pharos_dto/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8fe8f46958ddb3e42087a9fb10c4343d5bb5249cc279101bdc7d809777eeed74 +size 144909 diff --git a/pharos_dto/basic/plot_13.png b/pharos_dto/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..68781f55839be947880464a4f38109614764fe32 --- /dev/null +++ b/pharos_dto/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c82c3f5d6c39a61dd6232774fdcabdd64c20da684cb3a6dda85904a724b599c7 +size 152465 diff --git a/pharos_dto/basic/plot_14.png b/pharos_dto/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a33da43dba6f6f2cacb2172350f5907cfdf82675 --- /dev/null +++ b/pharos_dto/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61fd6876407d4c9e67d3579bc887bc5ffa7668c9fa26ce0ae6e12063559bc8ad +size 145856 diff --git a/pharos_dto/basic/plot_15.png b/pharos_dto/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..382e407c0ec55a7646108180245a7fee4edeed60 --- /dev/null +++ b/pharos_dto/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e837d41f6bcfabb953939b82faad015777633a2c3daad0db5f31d5c113ce55b3 +size 147199 diff --git a/pharos_dto/basic/plot_16.png b/pharos_dto/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..5e1c32e77ed5678ff7998c98849d6502d458741b --- /dev/null +++ b/pharos_dto/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b3643168ad939a034a39f0b381d379cada4990abd8719e506ab2d6dbf3fcdeca +size 147054 diff --git a/pharos_dto/basic/plot_17.png b/pharos_dto/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..2da7c606ede54b390d28a1b9c6b133b87d5a4d3d --- /dev/null +++ b/pharos_dto/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f4067b6b0b0a2bf136e729651364f901ac957191a81bd4fe98cc3083d1ffaaf +size 142528 diff --git a/pharos_dto/basic/plot_18.png b/pharos_dto/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..1292f0cc138d7b84a12b1a5365ad4a503da85f20 --- /dev/null +++ b/pharos_dto/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a592139c7be840326c0b9319d51e9cd4eff55dac6ac80fe608d3697154f07a1 +size 154610 diff --git a/pharos_dto/basic/plot_19.png b/pharos_dto/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..92d8919d6164051c536f6fd8dcb1106d786e840d --- /dev/null +++ b/pharos_dto/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d8a597c0200ccb865d3485bdc668fce22c384095998e1494430e1afb791ad3e +size 147276 diff --git a/pharos_dto/basic/plot_2.png b/pharos_dto/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..76472186966ed9c0bbe526b7a8263e8e58ac421e --- /dev/null +++ b/pharos_dto/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9af0339e3bc54e747c7ef6ecedebe6cfd5309790ede4370517dd589f92b0309 +size 136063 diff --git a/pharos_dto/basic/plot_20.png b/pharos_dto/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..c4ad661ee1e27be01dd78ab43406197fa4d872d9 --- /dev/null +++ b/pharos_dto/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a60d48b3485484bff3e339542775e2fd49bddd1f33249db6694adac4b85c250 +size 151747 diff --git a/pharos_dto/basic/plot_21.png b/pharos_dto/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..282ef8acaea1de2ff2f8528f09660fd512fe0788 --- /dev/null +++ b/pharos_dto/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86718e3c702d282bf32aac2e08f0ffd2f6334f23864b0027b40f1f889c6817c7 +size 146736 diff --git a/pharos_dto/basic/plot_22.png b/pharos_dto/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..01bd248abbe8024fe4ea0e66d9112e539dc82949 --- /dev/null +++ b/pharos_dto/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a3f6964dbf494df7e3c363f590a39ecb433f38f63e93afe0f171c9b28d8e88e +size 145301 diff --git a/pharos_dto/basic/plot_23.png b/pharos_dto/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..dd0ca9c11b69f027343d121e0ae41aea811c2c2f --- /dev/null +++ b/pharos_dto/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64fa71a3b30d8169307e1a196bd70f531e682e74851fc84268711a7d337c4dc7 +size 144915 diff --git a/pharos_dto/basic/plot_24.png b/pharos_dto/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..fe82b44ecaac591894badcaf38a8f8ffe0c8a4aa --- /dev/null +++ b/pharos_dto/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0c56006370d01a2d3c96c4012ca584d796210d29a75ec1e69b59a42a0bbabbe +size 140915 diff --git a/pharos_dto/basic/plot_25.png b/pharos_dto/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..3ed2d7f88d2b56307d44fb3ce5dc2061566b897f --- /dev/null +++ b/pharos_dto/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e624ec8b207fe2097f31b86473d8d83fce83d2ea69bc74fc3a45dc68f55988b7 +size 147376 diff --git a/pharos_dto/basic/plot_3.png b/pharos_dto/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..29759bf70a725509007c31dd62dec69e3690e7d3 --- /dev/null +++ b/pharos_dto/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8d8943ea76e6b658f6fc538a60e1ebdf3f6841fe6d455c02b13d5707468d78d +size 141747 diff --git a/pharos_dto/basic/plot_4.png b/pharos_dto/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..94438de1dcc48150a83a356da483664edab2742e --- /dev/null +++ b/pharos_dto/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b84049e7eb859f9002fca3d34d2ad168409dc198409cf8356ae3a998d769e3c1 +size 139477 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..0fbeffb1f6675b41be240e0a37b9bfb30beebf9f --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99a2f5bd473bf1f181baf07ddfaa626f9a24fe5e06acce6cdd32b08182fd701a +size 134615 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d32eb099b84b5fd447d982b237aba64cebce18a5 --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c20e3ae7e8dbb844cb49328edf105dfe68a463cb7924e789fabb455f33944906 +size 140750 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..21c1a38f28b6548a59a02967779c98da2d4268f6 --- /dev/null +++ b/pharos_dto/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c896470723eea643bc12085cac8c7194306ce1a6abd5f0b92447d62919f5194 +size 138190 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..1a7cceec2a794fc2c500df308d515602add359ca --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d37e78fb70a641a955c602f666a5efb29819981405ad19d42362b17ca0e4a657 +size 146452 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3bb23402c243839164a5450d9c86230c60b64b3b --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c359be0f4bffe75ae53ea4b50c12acfa3414d7090d697ca8439fc05c9aaced2 +size 149736 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..46cdd54ea54bc4e2f9e2406f40395b384826cc9b --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c2c4a4ab2b520c1ddba99871280ad05a10d40b8739cf323795e1b45260a9f20 +size 653426 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..54788d581a65b07944b88c53fad2fc45ffa4835a --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +SLC25 family of mitochondrial transporters 6 19 3.034614569403401 0.0024084325990028 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0125009202076431 0.0003996291666218 2.4880325513906888e-05 0.0003323148542865 +Receptor 6 27 2.747759765352337 0.0060003956244714 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0001197511089004 0.0033392088125754 0.0143893569832829 0.1451282622080898 +Transporter 35 172 2.508040516020535 0.0121402746011536 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 0.0726434620946438 0.042244985540561 0.0036910135251324 0.0083142374534142 +Mitochondrial nucleotide transporter subfamily 3 9 2.230600306121864 0.0257076165154415 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0021019285577768 0.0003495610743441 0.000371706641515 0.0005388274165263 +Signaling 2 16 2.1374432811164623 0.0325619543151587 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.3352443911727534 0.2040732901381184 0.3595041155184194 0.8097276750824585 +Oxygenase 1 5 2.104281250441657 0.0353539206046167 1.325242718446602 5.089805825242719 0.6977327730253281 0.3871728673651154 1.2525871050154007 0.6417459204185357 0.96253954683313 0.2912793467281958 1.0 1.0 0.290751966651369 0.1467539296032722 +SLC superfamily of solute carriers 7 38 2.099055239809413 0.0358120315117311 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.204582459674991 0.0952546806437235 0.0749794827600841 0.5312335336144824 +Reductase 3 16 2.028180913930678 0.0425417871116213 4.563106796116505 16.313106796116504 1.2016212969729014 0.3130807121312539 1.9089462498224232 1.180966799206311 0.8349037556988175 0.2876306629725971 0.0003084061297489 0.0025491163441 0.0049571663496986 0.012132108209414 +P-type ATPases 1 6 1.9937843251410416 0.0461756293017794 3.2815533980582523 6.757281553398058 0.5021561418998097 0.3946150755400491 1.82441625577419 1.518277124105495 1.19746001211325 0.3286800838620415 1.0 1.0 0.4172977923286156 0.2914565107291916 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..71a0906300b75a8b95f5f73c08e340dfe853e812 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 2102, + "title": "Average number of proteins per term", + "value": 3.1665080875356804 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3892d65ab1af2e5968cad9ed7a5353fa9745bce7 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..466d12551d7ae64961cb1bdd957b870ccfb2083b --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,87 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC25 family of mitochondrial transporters 0.7518618889276394 3.0346145694034012 0.0024084325990028 0.9937089765119332 0.0075813790031495 19 P53007,Q70HW3,Q9H2D1,Q9Y6C9,Q9UBX3,Q9BSK2 6 +Receptor 0.6165145634023939 2.747759765352337 0.0060003956244714 0.9999967950839164 0.0142196523141363 27 Q9ULC4,Q567V2,O75381,Q9UQB8,Q14108,Q8WTV0 6 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.9065092973613962 2.6505144204737245 0.0080369296319058 0.9999999569919472 0.0177082034447233 3 Q9UBX3 1 +Transporter 0.3482532700061167 2.508040516020535 0.0121402746011536 0.999999999992929 0.0237605746849394 172 P24390,Q70HW3,Q9H2D1,Q15075,Q93050,Q8WUX9,P51572,P55735,Q9Y487,P08183,Q9H267,P50542,Q9Y5K8,Q9HD45,Q12846,Q9HC21,Q9Y5P4,Q00169,P06576,Q9Y6C9,Q9UBX3,Q9UPT5,Q9BSK2,Q9P2W9,P18859,P53007,O43760,Q08379,P12235,Q92544,Q9Y3B3,Q96EE3,Q8NB49,P53985,P16615 35 +Miscellaneous SLC25 mitochondrial transporters 0.7441027172289976 2.2787903494286272 0.0226795308558251 1.0 0.0379859552660912 2 Q9Y6C9 1 +Mitochondrial nucleotide transporter subfamily 0.7878548805857718 2.230600306121864 0.0257076165154415 1.0 0.0416312865296287 9 Q9H2D1,Q9BSK2,Q70HW3 3 +ROCK subfamily 0.7199163929531207 2.1606266676822905 0.0307241897179815 1.0 0.0479828992490054 2 Q13464 1 +CAMKL family 0.8634598147594873 2.1395146929633713 0.032394007256524 1.0 0.0501368871174874 4 P54619,P54646,Q7KZI7 3 +CAMK2 family 0.7154374440131412 2.1385878527242252 0.0324690621538641 1.0 0.0501838004760458 2 Q13555 1 +Signaling 0.6451514954468424 2.1374432811164623 0.0325619543151587 1.0 0.0502534713439527 16 O15173,P43490 2 +Oxygenase 0.8402854811940527 2.1042812504416575 0.0353539206046167 1.0 0.0531953766005042 5 Q16850 1 +SLC superfamily of solute carriers 0.4733051171964114 2.099055239809413 0.0358120315117311 1.0 0.0536542339541403 38 P53007,Q70HW3,Q9H2D1,Q9Y6C9,Q9UBX3,Q9BSK2,P53985 7 +Reductase 0.6263468273726435 2.028180913930678 0.0425417871116213 1.0 0.0617134827526764 16 Q9H7Z7,P00374,Q15392 3 +P-type ATPases 0.7999121027524753 1.993784325141042 0.0461756293017794 1.0 0.0658488282173272 6 Q8NB49 1 +Actin binding motor protein 0.7639743277109499 1.9327229700527928 0.0532703339706359 1.0 0.0738616372073066 7 P06753,P67936 2 +PI3/PI4 kinase family 0.720900323781416 1.828769378828956 0.0674341640466653 1.0 0.0886729206827922 3 Q9UBF8 1 +Extracellular structure 0.7540123227950973 1.7926026644094015 0.0730364800842333 1.0 0.0941633096540208 6 O43290,Q32P28 2 +Carbohydrate kinase 0.6419826813974328 1.770591340138408 0.0766286830585731 1.0 0.0981556927416946 2 P17858 1 +Membrane trafficking regulatory protein 0.5029642049033 1.742523084744121 0.0814169556482413 1.0 0.1031575893746855 24 P24390,O43760,Q15075,P55735,Q96EE3 5 +PKN family 0.6360107494774424 1.74017511115275 0.0818282744994109 1.0 0.103444485792778 2 Q16512 1 +SLC35 family of nucleotide sugar transporters 0.6321289937294593 1.7203694718101017 0.085365302566279 1.0 0.1068082535680467 2 Q8TB61 1 +DMPK family 0.6869772998805185 1.6715805227948477 0.0946070681420643 1.0 0.1156186379271042 3 O75116,Q13464 2 +V-type ATPase 0.6849446719242086 1.664725931137518 0.0959674470718514 1.0 0.1168734494467159 8 Q9Y487,Q93050 2 +DNA ligase 0.6195879366975218 1.656203106594698 0.0976806943474828 1.0 0.1183428354572962 2 P18858 1 +Helicase 0.4874643104198062 1.6300794322590173 0.1030847100858867 1.0 0.1235370927026988 24 P46063,Q7Z478,Q9UL03,P33991,Q14147,Q14566,Q92620,P25205 8 +Aspartic protease 0.7361532975163801 1.6042265805457785 0.1086641177388085 1.0 0.128973447479941 4 Q5BJF2 1 +Calmodulin 0.5664543775646531 1.536082224770571 0.1245182152317305 1.0 0.1439406291040859 14 P80303,O43852,Q14257,Q15293 4 +Intracellular calcium-sensing protein 0.5664543775646531 1.536082224770571 0.1245182152317305 1.0 0.1439406291040859 14 P80303,O43852,Q14257,Q15293 4 +ATP-binding cassette transporter family 0.7193660308709661 1.5320796647611796 0.1255027771763406 1.0 0.1447102784556598 4 P08183,P28288 2 +Ribonucleoprotein 0.5492555988689793 1.50066230011084 0.1334429287037819 1.0 0.151702020624851 15 P09132 1 +Endodeoxyribonuclease 0.5783816064496907 1.4437910893862216 0.1487977492448509 1.0 0.1660635456982502 2 Q9UPY3 1 +DNA helicase 0.5611944497495098 1.4179857157641504 0.1561949351774441 1.0 0.1727100230105142 13 P25205,Q14566,P46063,P33991 4 +SLC56 Sideroflexins 0.5476261570618154 1.2843437143872696 0.1990217176726854 1.0 0.2105403374675312 2 Q9H9B4 1 +Microtubule binding motor protein 0.5005181572192486 1.2719912956811168 0.2033762119601023 1.0 0.2150386305533879 16 Q9Y496,P33176,Q99661,O00139,Q9BW19,O95235,Q13561,Q9NS87 8 +F-type and V-type ATPases 0.4997746993052166 1.2674415644366928 0.2049974457094063 1.0 0.216643856652173 16 P18859,P06576,Q9Y5K8,Q93050,P56134,P25705,Q9Y487 7 +ERK subfamily 0.5931899641576953 1.230596773781083 0.2184737124863121 1.0 0.2306538139860512 3 P27361,Q13164 2 +CK1 group 0.5564516129032134 1.0578866411391523 0.2901071262432031 1.0 0.3050551172402266 3 Q99986,Q8IV63 2 +STE group 0.5277114403814421 1.019508337214624 0.3079616971268097 1.0 0.323344399280996 10 Q13043 1 +Protein arginine methyltransferase 0.5977442159675259 1.0071044979884958 0.3138845599132134 1.0 0.3293985746068769 4 Q99873 1 +Na+/K+-ATPases 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.3481543796345365 3 P54709,P05023 2 +Tubulin 0.554874191588185 0.9656045474343642 0.3342420989703778 1.0 0.350412414980416 7 P04350 1 +Metalloprotease 0.3460280582782463 0.9258427458839574 0.3545277090558665 1.0 0.3711241257148562 38 P53582,P22695,Q96TA2,O95630,Q10713 5 +Calcium-binding protein 0.4216153029109828 0.9007693095442808 0.3677109885877259 1.0 0.3847329507274264 18 P80303,O43852,Q15293 3 +CDK family 0.5136597398774535 0.8930041305378339 0.3718549606821688 1.0 0.3888751877382681 9 Q00534 1 +CAMK group 0.4978485859843056 0.8690039452120545 0.3848449728833896 1.0 0.4020597082509368 10 P54619,O14757,P54646,Q7KZI7 4 +Oxidase 0.3948005660859624 0.8410568093340884 0.400316109645934 1.0 0.4180151328741944 21 O43169,P36551,Q15800,Q709F0 4 +MLK family 0.4601373544341657 0.836576950538138 0.4028304061582457 1.0 0.4204317347292118 2 Q13418 1 +Lyase 0.3906551505795152 0.7602203952768211 0.4471228557757021 1.0 0.4661965490280386 19 O95900,O96005,P53701,A1L0T0 4 +Actin family cytoskeletal protein 0.3041302524930753 0.7452592890136741 0.4561149870165215 1.0 0.4751009428685472 52 P35241,P15311,P06753,P61160,Q9BR76,Q9UKS6,Q14651,Q9UNF0,P59998,P26038,P67936 11 +Nucleotide phosphatase 0.4910554000078089 0.7384398183169396 0.4602472254523744 1.0 0.4791677404164888 8 Q5TFE4 1 +Methyltransferase 0.4080309613206105 0.714064989348315 0.47518699376992 1.0 0.4944767628239465 16 Q9BV86,P04818,P34897,P21964,Q96FX7 5 +Nucleoside kinase 0.4751529618288695 0.6883642213793058 0.4912234488020786 1.0 0.5109112762899402 3 P55263 1 +Ubiquitin-protein ligase 0.3882137159439291 0.6441447436734774 0.5194815782981159 1.0 0.5392347049790813 17 Q8TDB6,Q96PU5,Q93034,O95376 4 +Protein kinase 0.2794598922925035 0.6432050988872503 0.5200910252078579 1.0 0.5396008563607687 79 Q13555,Q6P3W7,P54619,Q16512,Q13177,Q13043,Q00534,O15111,P42345,P54646,Q7KZI7,Q13464,P78362,P24941,P36507,O14757,P17252,P67870,P27361 19 +Cellular structure 0.2781040925366327 0.585188449897978 0.5584210102879914 1.0 0.5785120569863765 113 P35221,Q96FJ2,Q03001,Q14651,Q13409,P04350,P23258,O00139,O95235,P67936,Q9BZD4,P52907,P15311,P61160,Q16527,P47755,O43237,Q13561,O43663,P33176,O00192,P06753,Q9UKS6,Q92747,Q99661,Q9NYL9,Q9BW19,Q9NS87,P35241,Q9Y496,Q9Y4I1,O75122,P30622,Q9BR76,O60333,Q9UEY8,Q9UNF0,P59998,Q9BSJ2,P26038 40 +Transcription cofactor 0.3702543955911579 0.5838415041909567 0.5593269516547985 1.0 0.5791651489548703 18 Q15650,O00625 2 +Immune response 0.4873694264348105 0.5832154608723307 0.5597482644163485 1.0 0.5793160274757088 5 Q6AI08,Q9NUQ3 2 +Major histocompatibility complex antigen 0.442641946843375 0.5513154798281005 0.581417428714146 1.0 0.6011507305249065 3 Q6AI08 1 +Chromatin/chromatin-binding protein 0.3403343657048784 0.5343642891717507 0.5930895209004281 1.0 0.6129174891507865 23 Q9UQR0,O75446,P26583,P09429,Q9UBU8 5 +RNA helicase 0.4241940565458288 0.5181148261099031 0.6043781565178912 1.0 0.6239699828097285 10 Q14147,Q9UL03,Q7Z478 3 +F-type ATPase 0.4383842950870471 0.5079444134092138 0.6114923264902556 1.0 0.6306952258501066 8 P18859,P25705,P06576,P56134 4 +CMGC group 0.3362981499021421 0.4453437880912013 0.6560713281065569 1.0 0.6760107508235208 20 P24941,P78362,Q00534,P27361 4 +STE7 family 0.4417894397171916 0.4143024460277964 0.6786526227189564 1.0 0.6989357241328988 5 P36507 1 +Small GTPase 0.3163464599960031 0.4063519325468425 0.6844840324137513 1.0 0.7040649366709157 24 O60313,Q14141,P50570,O00429,P63000,Q15019 6 +DNA binding protein 0.2571439430347698 0.3200536778877743 0.7489276397867599 1.0 0.7668026784372963 64 Q9UQR0,O75446,P26583,P33992,P09429,P16104,Q9UBU8,Q04837,Q9UBD5,P54725,Q8IWS0,P17096 12 +Kinase modulator 0.3182007211114946 0.2724744756527213 0.7852572145555168 1.0 0.8028261989278678 17 P60983,Q2TAL8,O95067,Q9NQG5 4 +Ribosomal protein 0.2543944130378698 0.2704585383069207 0.7868075103215895 1.0 0.8040201199299859 106 P62841,P31942,P61254,Q16540,P62081,P46778,P50914,O60506,P08865,P25398,P84098,P62917,Q96A35,P62899,P55769,P46782,P62753,P15880,P78316,Q92552,P27635,O43390,Q9Y3D3 23 +Acyltransferase 0.3519966843684607 0.2565686166787054 0.7975118044193388 1.0 0.8145625912971088 11 P49354 1 +Kinase 0.2504476124768089 0.2362810073104078 0.8132146237143525 1.0 0.8297947276929946 120 P04183,Q13555,Q6P3W7,P54619,P35790,Q16512,O75569,P12532,Q13177,Q13043,Q00534,O15111,P42345,P54646,P55263,Q7KZI7,Q9Y3D8,P42356,Q13464,P78362,P24941,P12277,P36507,P48426,O14757,P17858,P17252,P67870,Q99570,Q9UBF8,P27361 31 +Microtubule family cytoskeletal protein 0.2510922263940418 0.2187929138884988 0.8268113670487449 1.0 0.8424418291500058 50 Q9Y496,O43663,P33176,P30622,O60333,Q96FJ2,O43237,Q99661,P63167,Q13409,P23258,O00139,P04350,Q9BW19,O95235,Q9BSJ2,Q13561,Q9NS87 18 +Lipid kinase 0.3501297682632102 0.1771330221945892 0.8594039040722279 1.0 0.8748024243873235 7 P42356,Q9UBF8 2 +mRNA splicing factor 0.2405662788815289 0.1654979706368945 0.8685520470062587 1.0 0.883686545405206 59 Q9BZJ0,Q09161,Q15233,Q13595,Q8IY67,Q8WXF1,Q96PU8 7 +Translation initiation factor 0.279544302670502 0.1640981551752717 0.8696538740843276 1.0 0.8843795081399404 21 O75153,P55010 2 +Translation elongation factor 0.3517870729060083 0.1542796732488016 0.8773892238193606 1.0 0.8913833487038647 4 P29692 1 +Glycosyltransferase 0.2822538868600898 0.1430384080755803 0.8862598478013959 1.0 0.8995259295405766 18 P04844,Q10472,P35573,P46976,Q8N128,Q9H6U8 6 +Translation factor 0.2588987493756621 0.1313847872185704 0.8954709223823478 1.0 0.9066858761308744 27 O75153,P55010,P29692 3 +Actin and actin related protein 0.318983557548591 0.1006053777387293 0.9198637275514588 1.0 0.9300401901458232 6 O96019,P61160,P61163,P61158,Q9GZN1 5 +Chromodomain 0.3183931757900688 0.0982672284351392 0.921720100122966 1.0 0.931021456251069 5 P83916 1 +AGC group 0.3020430829918724 0.0917018367914228 0.9269349379946096 1.0 0.9358392121348076 9 P17252,O75116,Q13464,Q16512 4 +Decarboxylase 0.3054035277257216 0.0808284433087714 0.9355783875815464 1.0 0.9436591989906 4 A1L0T0 1 +Phosphatase inhibitor 0.2913360057974334 0.0613322454045852 0.9510946110125 1.0 0.9576878478040676 6 P55209 1 +Serine protease 0.2420182021263604 0.0527631498344667 0.9579206227532536 1.0 0.9638818329475056 26 P42785,Q9HB40,Q15366 3 +Protein phosphatase 0.2674453429170329 0.0424468521943828 0.9661424793327228 1.0 0.9714855526341558 12 Q14738,Q9H0C8,Q8TF05,Q9Y5B0,O15355,P63151,P49593,P30153,P62136,P62140,P30154 11 +G-protein 0.2333682698882527 0.0421217261338757 0.9664016605889724 1.0 0.9714855526341558 34 O60313,Q14141,P50570,O00429,P63000,Q15019 6 +Chaperonin 0.262196947021852 0.0301487786734152 0.9759483986371924 1.0 0.9806135439461656 10 P49368,P50991,P78371,Q99832,P17987,P61604,P50990,P40227,O75347 9 +Non-protein kinase 0.2395388081304922 0.0210082061089727 0.9832391095929788 1.0 0.986524395400688 21 P42356,P48426,Q9UBF8,P17858,P35790,P55263 6 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ef2160c8fd2c0ceb2131e6f987d7ea7e650f7a8b --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L27, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AF4/FMR2 family member 4", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 2, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-1,2-mannosyltransferase ALG9", "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Autophagy protein 5", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CAP-Gly domain-containing linker protein 1", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CDC7 family", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcium/calmodulin-dependent protein kinase type iv", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-6", "Caspase-7", "Caspase-8", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle 7-related protein kinase", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromobox protein homolog 6", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Collagen type IV alpha-3-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Mlh1", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA repair protein complementing XP-C cells", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-beta-1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Dachshund homolog 1", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity mitogen-activated protein kinase kinase 7", "Dual specificity protein kinase clk2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZFP91", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endoribonuclease LACTB2", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor kinase substrate 8", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2 subunit 3", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 5", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Folylpolyglutamate synthase, mitochondrial", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HDAC class IIb", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone chaperone ASF1A", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase 6", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "IRAK family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol polyphosphate 5-phosphatase K", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrator complex subunit 6", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Interleukin-1 receptor-associated kinase 1", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin heavy chain isoform 5C", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF15", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LIM domain-containing protein 1", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Lethal(3)malignant brain tumor-like protein 3", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3A", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase inducer phosphatase 3", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 3", "MAPK family", "MARK subfamily", "MAX gene-associated protein", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "Magnesium transporter protein 1", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial intermediate peptidase", "Mitochondrial mRNA pseudouridine synthase TRUB2", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase 7", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mothers against decapentaplegic homolog 4", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor of activated T-cells 5", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoplasmin-3", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 5", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 3", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase and actin regulator 4", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipase DDHD2", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphoribosyltransferase domain-containing protein 1", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Phosphotriesterase-related protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ENL", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein NDRG1", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein VAC14 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein prenyltransferase alpha subunit repeat-containing protein 1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase I-specific transcription initiation factor RRN3", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA polymerase-associated protein LEO1", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoblastoma-associated protein", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "Ribosome-releasing factor 2, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC35 family of nucleotide sugar transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Sedoheptulokinase", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-10", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor SPT20 homolog", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transcriptional repressor protein YY1", "Transducin-like enhancer protein 3", "Transducin-like enhancer protein 4", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II pantothenate kinase family", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Vacuolar protein sorting-associated protein 72 homolog", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WD repeat-containing protein 92", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "ZZ-type zinc finger-containing protein 3", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger E-box-binding homeobox 1", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger and BTB domain-containing protein 10", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALG9", "AMPD2", "ANAPC1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BCR", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CBL", "CBX1", "CBX3", "CBX5", "CBX6", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHM", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTOP", "CHUK", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK2", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COASY", "COIL", "COL4A3BP", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA7", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERC1", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FNTA", "FNTB", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFM2", "GFPT1", "GGH", "GINS1", "GINS2", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INPP5K", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3A", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEO1", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARK2", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED20", "MED21", "MED25", "METAP1", "METTL1", "MFN1", "MFN2", "MFSD5", "MGA", "MGAT2", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MIPEP", "MLH1", "MLLT1", "MMS19", "MORF4L1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "NCOA5", "NCOR1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NF1", "NFAT5", "NHP2", "NIPBL", "NKRF", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPM3", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTAR1", "PTCD1", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRN3", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "SAE1", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLK", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT20H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAB1", "TAF15", "TAF6", "TAGLN2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM40", "TOP1", "TOP3B", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIP4", "TRMT61A", "TROVE2", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UCHL5", "UCK2", "UGGT1", "UPF1", "UQCR10", "UQCRC1", "UQCRC2", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "WARS", "WASF2", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR74", "WDR82", "WDR92", "WIZ", "WNK1", "WRNIP1", "XAB2", "XIAP", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZEB1", "ZFP91", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCD3", "ACAD11", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADD3", "ADK", "AGL", "AK6", "ALG9", "ARIH2", "ARPC1A", "ARPC4", "ARVCF", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP5A1", "ATP5B", "ATP5J", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAIAP2", "BCAP31", "CALU", "CAMK2G", "CAPZA1", "CAPZA2", "CBX1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CDK2", "CDK6", "CHEK1", "CHKA", "CHMP7", "CHUK", "CKB", "CKMT1A*", "CLASP2", "CLIP1", "CLPTM1", "CLUH", "COL4A3BP", "COMT", "CORO1B", "CPOX", "CRNKL1", "CSNK2B", "CSRP2", "CTDP1", "CTNNA1", "CUL5", "CYB5B", "CYP51A1", "DCTN2", "DHCR24", "DHFR", "DHX29", "DHX34", "DHX38", "DICER1", "DNM1L", "DNM2", "DST", "DTX3L", "DYNC1I2", "DYNC1LI2", "DYNLL1", "DYNLL2", "EEA1", "EEF1D", "EIF5", "EXOC7", "EZR", "FAM177A1", "FNTA", "GALNT1", "GMFB", "GOLGA2", "GYG1", "H2AFX", "HCCS", "HEATR6", "HMGA1", "HMGB1", "HMGB2", "HNRNPH3", "HNRNPR", "HSPE1", "ILK", "ILKAP", "ILVBL", "INTS6", "KDELR1", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFC1", "LIG1", "MAP2K2", "MAPK3", "MAPK7", "MARK2", "MCM3", "MCM4", "MCM5", "MCM6", "MCTS1", "METAP1", "MORF4L1", "MPV17L2", "MRPL23", "MRPL24", "MRPS16", "MRPS27", "MSMO1", "MSN", "MTCH2", "MTOR", "MYO5A", "NAMPT", "NAP1L1", "NCBP1", "NEDD4L", "NONO", "NOP14", "NT5DC1", "NTMT1", "NUCB2", "NUF2", "OPA1", "ORC3", "P3H1", "PACSIN2", "PACSIN3", "PAK2", "PCBP2", "PEX14", "PEX5", "PFKL", "PGRMC2", "PHF6", "PI4KA", "PI4KB", "PIK3R4", "PIP4K2A", "PIR", "PITPNA", "PKN1", "PLS1", "PMPCA", "PPM1F", "PPM1G", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PRC1", "PRCP", "PRKAA2", "PRKAG1", "PRKCA", "PRKRA", "PRMT1", "PSPC1", "PTGES2", "QKI", "QRICH1", "RAC1", "RAD23A", "RAVER1", "RCN1", "RCN2", "RDX", "RECQL", "ROCK1", "ROCK2", "RPL10", "RPL14", "RPL19", "RPL21", "RPL26", "RPL31", "RPL8", "RPN2", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS5", "RPS6", "RPS7", "RPSA", "SAP30", "SART1", "SCARB1", "SCARB2", "SCML2", "SCPEP1", "SCYL2", "SEC13", "SEH1L", "SEPT2", "SEPT6", "SFXN1", "SHMT2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC35B2", "SNU13", "SRP19", "SRPK2", "SSBP1", "STAMBP", "STK4", "STX18", "STX4", "SYNCRIP", "SYNGR2", "TBCA", "TCP1", "TK1", "TM9SF3", "TM9SF4", "TMED7", "TMEM97", "TMOD3", "TPM3", "TPM4", "TRA2A", "TRIP4", "TRMT61A", "TRUB2", "TUBB4A", "TUBG1", "TUBGCP2", "TXLNG", "TYMS", "UQCRC2", "VPS33B", "VRK1", "VRK3", "YME1L1"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..37b3ad5cc03d2c08d8055be4b83851c8d6658c6b --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tchem", "2": "Tbio", "3": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4b53a5ac16f05a3adc4c41f5721a44a05fda159f --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:39e55799398898ea6f06fd830eb2ebd0363bc1563846faf8e866106bbdd39874 +size 129065 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..711563d342ad6144234586ed6f19eb73c434b552 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b45c4bf2b49ace9183df4974000225fd288cbea51f55dc512ba69551f440854e +size 135428 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a1a17de5113e09fb74db13afff900b198154b2f9 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a83e01a24e18e6c4a072c835c68e702cf084cf28c216495ce4b1711a585e634a +size 129737 diff --git a/pharos_protein_category/basic/plot_3.png b/pharos_protein_category/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..55e07013d28d54a68a309d2d721a5616db8676f4 --- /dev/null +++ b/pharos_protein_category/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d5834fa49f6acb25f82a842d959e4e06ab6257eb80c21e862c880c3c48db4ab5 +size 137419 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..44a392873bbece01ade53b5d1c89e2e611ba2ad1 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f7d6ba5a26175f903ca8330c931785ef3b22bf302714d191d7d10bcc5469701e +size 73802 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0739ae1590d1e613240eeacec8012f607e48dfd3 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 837.5 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c89f21199b5e530c24e505de90e2108c31b611f0 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1d40eb1d6c44c3c22423adb06e4c617feb42ec7f --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.2723742744906369 1.6339383902893891 0.1022717877135916 0.3504994926009031 0.4090871508543667 338 O60830,Q92665,Q14997,O43615,Q15006,Q9H0A8,Q9GZN8,Q9H2W6,Q8N8E3,Q6IAN0,Q96FJ2,Q52LJ0,O75964,Q6ZXV5,Q5T1M5,Q9NVM9,Q9NVM6,Q96CT7,Q96FX7,Q9BTE6,Q15345,Q9NWV4,Q5TFE4,Q8N4H5,Q96PV6,Q9P260,Q5SWX8,P14406,P47755,Q9HD20,Q16540,Q9HD45,Q96C01,Q9NR33,Q9H1E5,O95070,Q9Y2W6,Q9NWZ8,Q9NWH9,Q9Y5M8,Q66K14,Q9BWH6,Q2VPK5,Q9NRY5,Q86TU7,Q2TAL8,P82933,Q6P3X3,Q9Y3C1,Q8WVC6,Q5JVF3,Q9BTE7,Q9Y2L5,Q8N128,Q9BWJ5,Q9H7E9,Q9Y383,Q5SNT2,Q96A35,Q4VC31,Q96GQ7,O95900,Q6UW68,Q969T7,Q8IW92,Q9P0I2,Q7Z6K3,Q9P0K7,Q9Y3B3,P78316,Q9H9L3,Q9BSJ2,Q70UQ0,Q9NUD5 74 +Tchem 0.2367133764066171 0.621782692591201 0.5340847683136434 0.9528775747175894 0.7090818221971893 350 Q09472,P43490,P30519,Q9H773,Q15125,P50570,P04062,P42892,P35790,Q13427,P08183,Q8WTV0,Q92993,P45880,Q9Y263,P07099,Q13043,P37268,O15111,P50579,Q9H7Z7,P09601,Q13907,Q5BJF2,Q16850,Q13126,P55263,P27695,Q4J6C6,Q7KZI7,P14174,P53582,P78362,P24941,Q99873,P42785,Q14534,P17252,O60725,O60502,Q8NCG7,P51159,Q9UBF8,Q15126,P53985,Q9NS86 46 +Tbio 0.1901115842938917 0.5048491597803813 0.6136647847142274 0.9777229752528876 0.7090818221971893 2576 Q9UJW0,P24390,Q99595,Q70HW3,Q9Y2C4,Q9H2D1,Q32P28,P09132,Q9NUJ1,O76071,Q93050,Q567V2,P21796,Q9NS69,Q9UQB8,Q9UHG3,P35613,Q14108,Q8NBX0,P57076,P67936,Q15392,Q9Y282,P49354,Q9ULC4,P07602,O43852,O95067,Q13503,Q9UBU8,Q96PU8,O75153,Q15165,P53004,O00625,O75607,Q00169,Q13561,P17096,O15173,O75695,P36551,Q00059,Q09161,Q8TDB6,Q96PU5,Q9BU89,P08670,Q9UBX3,Q9NQP4,Q9Y6N5,P22695,Q4G176,Q9H061,Q9BSK2,Q14566,P62899,P55769,P07197,Q68E01,Q969Z0,P16949,Q9Y5L4,P53007,Q96G23,Q8TBA6,Q8TCT9,P80303,O00264,P09429,P14854,P50897,P62753,Q92544,Q9P2R3,Q7Z7H8,Q9UBW8,Q96N66,Q8WVV9,P61960,Q13505,O43169,Q8IUD2,Q9Y3D3,Q9BTX1,Q9UDX5,Q7Z739,P67809,Q15293,P62841,Q15233,Q86XL3,Q9Y5J9,Q9UHX1,Q8WUX9,Q3LXA3,Q14789,Q03001,P55735,O75381,P33908,Q04837,Q13409,Q14157,Q5M775,Q99996,Q9HB40,Q9Y487,Q15019,Q15800,Q12959,P46199,Q6PJG6,Q9BZD4,Q9HA77,P15311,Q9BXJ9,Q9Y5K8,Q9NVH1,Q9NVA1,Q9H2J4,Q14141,Q8IY67,Q8IUF8,Q07065,P55036,Q15366,Q709F0,P51530,Q14257,P50914,Q10713,Q96A26,Q9BV86,Q9NR28,P46063,Q96KC8,P00367,P41567,P06753,O43290,Q9Y6C9,Q9UKS6,Q9H0B6,Q9H078,Q9UDW1,Q15650,P62917,O00429,P51116,O43347,Q06481,Q4KMP7,Q9UBD5,Q9P2W9,Q9BW92,Q6P4A7,P46782,P41227,P35241,P18859,P05455,O43760,Q9Y2X0,Q9UNH7,Q9NWY4,Q96EZ8,P61513,P55010,P12235,O15344,Q86UY6,Q9UL03,Q96EE3,Q96DE0,Q8NB49,P59998,P55209,P31483,P26038,P16615,O14979,Q8IY95,Q9Y4J8,Q9NUQ7,Q8N5C6,Q96BK5,Q6IN85,Q03252,O60568,P67812,P35240,Q13017,Q15075,Q9Y3A2,Q9NV88,Q9BPZ3,Q96GG9,Q96EY7,Q14651,P54619,P31948,O95630,O75879,O15127,Q9BQG2,Q8NEZ5,Q96HY6,Q9NZC3,Q9BZJ0,Q6UWP7,P50542,Q5T9A4,P26583,P15927,O60313,O15254,A1L0T0,Q96GX9,Q86WJ1,Q8NHP8,Q8WU90,Q8WXF1,Q9H6U8,Q96TA2,Q9BQ95,Q9H1A4,Q9H3F6,Q9UNN8,Q9Y3B2,Q8IWS0,Q6DKK2,O14828,O14981,O15091,O43681,O14737,P25490,Q13595,P25398,Q9H089,Q8IV08,Q8IWJ2,Q99459,Q9UPR3,Q9HCE1,Q9HCS7,Q9UPT5,Q14166,P83916,P61758,P55199,P53701,P51648,P29692,P18074,O96005,O94887,O60888,Q08379,Q9H993,Q9NPI6,Q8N511,Q9BR76,Q9NX63,Q9Y606,Q9UBZ9,Q9UJ41,Q9ULE6,Q9UNF0,Q96RU2,Q15036,Q6NYC1,P27635,O75330,O75937,P20042,O43390,P63000,Q13813,Q01968,Q14241,Q10472,Q86YR5,Q9Y285,Q9UQE7,Q9UJX5,Q9H3N1,Q9BY67,Q969Y2,Q93034,Q9P015,Q6P3W7,P51572,P46976,P40855,P30533,P23258,O75390,O00139,Q9BRT9,Q6FI81,Q7Z392,Q2TAA5,Q9BUJ2,Q9H0S4,Q9H267,Q9NRG1,Q9NYV6,Q14254,P61160,Q14103,P13051,O60318,P31942,P18615,P62081,Q00839,Q08426,Q12846,Q13144,Q8TAT6,Q8WW12,Q96AE4,Q96HR8,Q96JB5,Q9HC21,Q9Y5P4,Q9UG63,Q9Y312,Q9Y3D8,Q9Y4E6,Q13576,Q5PSV4,Q12873,P12277,O00231,O75448,O75718,P06576,P08865,P12270,P16104,P35244,P48651,P49458,P56134,P61289,P30043,Q9NWT6,Q8NE01,Q99471,Q9BQ70,Q9H299,Q9H4L4,Q9UIS9,Q9UBS4,Q9UHB7,Q9UJZ1,Q9UM00,Q9Y4I1,Q86U42,Q86UP2,Q86U06,O75122,P46939,O60294,P20700,P29373,P33992,Q86TV6,Q02543,Q06136,Q53GQ0,Q5JTV8,Q92552,Q96A33,Q9C0E2,Q9H074,Q9NXG2,Q9NVI7,Q9Y295,Q8IVW6,Q8N1F7,Q05682,Q16181,P35580,O95376,Q15648,P34897,P23381,P35754,P49257,P55145,P83436,Q96C36,Q6GQQ9,Q6UVJ0,Q7L5D6,Q86Y56,Q8IXB1,Q8N4J0,Q96CS3,Q96FZ2,Q96SU4,Q99623,Q9NYF8,Q9UBB9,Q9Y4A5,Q4VCS5,Q14185,Q15024,O14795,O75323,O75446,P16435,O43242,P57772,P61254,Q13610,P46778,Q99816,Q92643,Q96CB9,Q96F07,Q96G03,Q99543,Q9UJX4,Q9BXR0,Q9NXV2,Q9Y2S7,Q6NUM9,Q8NCN5,Q8NFF5,Q3YEC7,O43663,O60506,O00411,P28288,P35573,O94874,P48426,P51571,P84098,Q01081,Q08AM6,Q13310,Q8WYA6,Q92974,Q969G3,Q96EK5,Q96EY1,Q9UJX2,Q9GZZ9,Q9NNW5,Q9NQG5,Q9NS87,Q9P2T1,Q9UQR0,Q9Y2J2,Q9Y673,Q7LGA3,Q86XI2,P42285,Q5VTR2,P30622,O14925,O15400,O43708,O76094,P14373,P15880,P02545,P43307,P46776,Q01664,Q01085,Q14147,P60983,P54725,Q8TB61,Q8WVB6,Q8WXI9,Q96AX1,Q96D46,Q96HW7,Q96N67,Q99733,Q9Y4Z0,Q9H2M9,Q9NR45,Q9NR50,Q9NXN4,Q9NZM5,Q9UHB9,Q9UNZ2,Q9Y2A7,Q9Y5P6,Q8NEY8,P25705,Q8IYI6,P42695,Q8IYB8,O60231,O75431,O75569,O75844,P12532,P12814,P24539,P25205,P04844,P46379,P52907,P61923,Q01804,Q16204,Q6P4Q7,P50213,Q5T4S7,Q7Z478,Q6P6C2,Q6NUQ1,Q5VU43,Q14674,Q5T160,Q4KMQ2,Q16763,Q16543,Q96RP9,Q92888,Q9Y3Y2,Q99747,Q9BQ67,Q9BXK5,Q9HAV7,Q9NPQ8,Q9NZM3,Q9Y2B0,Q9Y394,Q12849,Q13084,Q01082,O00192,O14530,O60749,O60763,O95251,O95825,P08397,P14866,P17858,P17987,O95905,P19447,P23246,P30038,P30044,P33991,P35579,P36915,P62266,P62750,P20338,P67870,Q96BR5,Q9BXW6,Q99797,Q99570,Q96PZ0,Q6WCQ1,Q92547 572 +Tclin 0.2590681887862531 0.3730895147880407 0.7090818221971893 0.9928371899443658 0.7090818221971893 86 P38435,P28340,P04818,O43678,Q9P0J0,Q00534,P51970,P36507,P21964,O75380,O43676,Q86Y39,P04350,P49721,P00390,P00374,O75306 17 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c7a49b4185ecc5fd29ca10505409d73403c8bc9f --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf54", "C11orf98", "C12orf57", "C15orf39", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD5", "C5orf15", "C5orf24", "C7orf26", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPU", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG2", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R21", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM214", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROAP", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPO", "TSPYL1", "TSR1", "TSR3", "TSSC4", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["AAR2", "AARSD1", "ABCB1", "ABCD3", "ABCF2", "ABHD10", "ACAD11", "ACOX3", "ACSF3", "ACTN1", "ACTR2", "ADK", "AFF4", "AGL", "AK6", "AKAP9", "ALDH3A2", "ALDH4A1", "ALG11", "ALG5", "ALG9", "ALKBH5", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANKFY1", "ANKLE2", "ANO6", "APEX1", "APIP", "APLP2", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARID3B", "ARIH2", "ARMT1", "ARPC4", "ARVCF", "ASNA1", "ATAD3A", "ATAD3B", "ATP11C", "ATP13A1", "ATP2A2", "ATP5A1", "ATP5B", "ATP5F1", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAG6", "BAIAP2", "BCAP31", "BCL2L13", "BCLAF1", "BLVRA", "BLVRB", "BRAT1", "BRMS1L", "BSG", "BTAF1", "C1orf123", "C20orf27", "C21orf59", "C8orf33", "CADM1", "CALD1", "CALU", "CAPZA1", "CAPZA2", "CARNMT1", "CARS2", "CBX1", "CCDC124", "CCDC47", "CCDC58", "CCDC6", "CCNB2", "CDC23", "CDC37", "CDC5L", "CDK2", "CDK5RAP3", "CDK6", "CEP112", "CERS2", "CHCHD3", "CHD1L", "CHD3", "CHKA", "CHMP7", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKB", "CKMT1A*", "CLASP2", "CLIP1", "CLPB", "CLPTM1", "CLUH", "CNNM3", "CNNM4", "CNPY2", "COA7", "COG7", "COL4A3BP", "COMMD4", "COMT", "COPS7A", "COPZ1", "CORO1B", "COX6B1", "COX7A2", "CPOX", "CRABP2", "CRNKL1", "CRTAP", "CRYZL1", "CS", "CSNK2B", "CTNNBL1", "CTU2", "CUL5", "CUTA", "CYB5B", "CYFIP2", "CYP51A1", "DAGLB", "DCAKD", "DCP1A", "DCTN2", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DDRGK1", "DDX27", "DDX47", "DHCR24", "DHFR", "DHRS7", "DHRS7B", "DHX16", "DHX29", "DHX34", "DIABLO", "DLG1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC17", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DOHH", "DRG1", "DST", "DTNA", "DTX3L", "DYNC1I2", "DYNLL2", "EBP", "ECD", "ECE1", "ECSIT", "EEA1", "EEF1D", "EEFSEC", "EHHADH", "EIF1", "EIF2B3", "EIF2B5", "EIF2S2", "EIF5", "ELL", "ELOA", "EMC2", "EMC3", "EP300", "EPB41L3", "EPHX1", "ERC1", "ERCC2", "ERCC3", "ERGIC3", "ESPL1", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC7", "EZR", "FAF2", "FAM114A2", "FAM136A", "FAM162A", "FAM177A1", "FAM98B", "FARP2", "FARSA", "FBXO22", "FDFT1", "FKBP15", "FLAD1", "FLOT2", "FNTA", "FUBP1", "FXR2", "GALNT1", "GATAD2B", "GATB", "GBA", "GCC2", "GDAP2", "GDE1", "GEMIN8", "GET4", "GFM1", "GGCX", "GINS4", "GLB1L2", "GLRX", "GLUD1", "GMFB", "GMPPB", "GMPR2", "GNL1", "GOLGA2", "GOLGA5", "GOLGB1", "GPSM1", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTZ1", "GTPBP3", "GYG1", "H2AFX", "HCCS", "HIF1AN", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMMR", "HMOX1", "HMOX2", "HNRNPD", "HNRNPDL", "HNRNPH3", "HNRNPL", "HNRNPLL", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPF1", "HS2ST1", "HSD17B12", "ICMT", "IDH3A", "IDI1", "IKBIP", "ILVBL", "INTS13", "INTS3", "INTS4", "INTS6", "INTS9", "IQGAP2", "ISG20L2", "ITSN2", "JMJD6", "KAT5", "KAT7", "KCTD10", "KCTD5", "KDELR1", "KDSR", "KIAA0391", "KIAA1468", "KIF15", "KIF2A", "KIFBP", "KLC2", "KTN1", "LANCL2", "LCLAT1", "LCMT2", "LENG8", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LRPAP1", "LRRC41", "LSG1", "LSM4", "LUC7L2", "MAN1A1", "MANF", "MAP2K2", "MARK2", "MBD1", "MBOAT7", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCRS1", "MCTS1", "MED1", "MED16", "MED21", "MED24", "METAP1", "METAP2", "MGEA5", "MID1", "MIF", "MIPEP", "MORF4L1", "MOV10", "MPRIP", "MPV17L2", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL28", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSI1", "MSMO1", "MSN", "MTAP", "MTCH2", "MTFP1", "MTIF2", "MTX1", "MTX2", "MYH10", "MYH9", "MYO5A", "NAA10", "NAA15", "NAA40", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPG", "NCAPD3", "NCAPG2", "NCBP1", "NCKAP1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NEFM", "NELFE", "NF2", "NIPSNAP2", "NMD3", "NONO", "NOP14", "NOP16", "NOP53", "NPLOC4", "NPM3", "NSFL1C", "NSUN4", "NT5C3B", "NT5DC1", "NTMT1", "NUCB2", "NUDT12", "NUDT16", "NUF2", "NUP93", "OCRL", "ODR4", "OPA1", "ORC3", "OSBPL1A", "OSBPL9", "OTUD4", "OTUD7B", "P3H1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAIP1", "PAIP2", "PALD1", "PCBP2", "PCID2", "PCNP", "PCYOX1", "PDCD5", "PDCL3", "PDE4DIP", "PDPR", "PEX14", "PEX19", "PEX5", "PFDN4", "PFDN5", "PFKL", "PGM2", "PGRMC1", "PGRMC2", "PHB2", "PHF6", "PI4KB", "PIGK", "PIK3R4", "PINX1", "PIP4K2A", "PIR", "PITPNA", "PLAA", "PLBD2", "PLD3", "PLOD3", "PLS1", "PMPCA", "PMVK", "POLD1", "POLDIP2", "POLE4", "POLRMT", "PON2", "POR", "PPHLN1", "PPIG", "PPP4R3A", "PPT1", "PRC1", "PRCP", "PRDX5", "PREPL", "PRKAG1", "PRKCA", "PRKRA", "PRMT1", "PROCR", "PRTFDC1", "PSAP", "PSMB2", "PSMD11", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSPC1", "PTAR1", "PTCD3", "PTDSS1", "PTGES2", "PUF60", "PUS1", "PUS7", "PWP1", "PYCR2", "QKI", "QRICH1", "QTRT1", "RAB27A", "RAB3GAP2", "RAB4A", "RABGEF1", "RABL6", "RAC1", "RAD23A", "RAI14", "RARS2", "RAVER1", "RBM23", "RCN1", "RCN2", "RDX", "RECQL", "RETSAT", "REV1", "RIC8A", "RINT1", "RIOX2", "RNF20", "RP2", "RPA2", "RPA3", "RPAP1", "RPL10", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL26", "RPL27A", "RPL31", "RPL37A", "RPL8", "RPN2", "RPRD1B", "RPS12", "RPS15", "RPS2", "RPS23", "RPS5", "RPS6", "RPS7", "RPSA", "RRN3", "SAP30", "SART1", "SASS6", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCML2", "SCPEP1", "SCYL2", "SEC11A", "SEC13", "SEH1L", "SENP3", "SEPT2", "SEPT6", "SEPT7", "SETD3", "SF3B5", "SFPQ", "SFXN4", "SH3BGRL3", "SHMT2", "SKIV2L2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC35B2", "SLTM", "SMARCE1", "SMC3", "SMG5", "SNU13", "SNX17", "SNX2", "SNX6", "SPECC1", "SPTAN1", "SPTBN1", "SQLE", "SQOR", "SRBD1", "SRP19", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRB", "SSB", "SSBP1", "SSR1", "SSR4", "STAMBP", "STIP1", "STK4", "STMN1", "STOML2", "STX18", "STX4", "STX7", "SUPV3L1", "SYNCRIP", "SYNGR2", "TARS2", "TBC1D10B", "TBC1D9B", "TBRG4", "TCF25", "TCP1", "TDRKH", "TFAM", "TFAP4", "TFIP11", "THUMPD1", "TIA1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8B", "TKFC", "TM9SF3", "TM9SF4", "TMCO1", "TMED7", "TMEM126A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM97", "TMTC3", "TMX1", "TMX4", "TOMM22", "TOMM5", "TOPBP1", "TOR1AIP1", "TPM3", "TPM4", "TPR", "TRA2A", "TRAPPC11", "TRAPPC8", "TRIM27", "TRIP4", "TRMT61A", "TRRAP", "TRUB2", "TSG101", "TTC19", "TTC27", "TTC7B", "TTLL12", "TUBB4A", "TUBG1", "TUBGCP2", "TXNDC9", "TYMS", "U2AF1", "UBA5", "UBAP2L", "UBE2S", "UBR4", "UFL1", "UFM1", "UFSP2", "UNC13B", "UNG", "UQCC1", "UQCR10", "UQCRC2", "USO1", "USP28", "UTP11", "UTRN", "VAC14", "VBP1", "VDAC1", "VDAC2", "VIM", "VPS33A", "VPS33B", "WARS", "WDR6", "WDR7", "XAB2", "XPO4", "YBX1", "YIF1A", "YME1L1", "YTHDF3", "YY1", "ZC3H15", "ZCCHC3", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json b/protein_atlas_biological_process/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..513ecad7c7127dc0693387e40fc29ef6e4ebc96e --- /dev/null +++ b/protein_atlas_biological_process/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Translocation", "1": "Transport", "2": "DNA recombination"} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/plot_0.png b/protein_atlas_biological_process/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..164036dc7c1b222ff613ec4b5bd487410d33ffe9 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae0f2b69ec4e261fca7c3ca76216e4db6798fcf3736c5d4a79ec4451352d5bb2 +size 206429 diff --git a/protein_atlas_biological_process/advanced/plot_1.png b/protein_atlas_biological_process/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..303da1f17cb35aace00addc91893c6334daced55 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd3704c4247440bc06a85c8be282fe8b2e939d12b4244a85af0869d78aefc84e +size 235609 diff --git a/protein_atlas_biological_process/advanced/plot_2.png b/protein_atlas_biological_process/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a97e86223b3bd00504a3b9355d66761fcdf2659b --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:22221c4ec90524628d07e7e45f3976a11c9704c9243193c7dd3b6f3194701770 +size 201046 diff --git a/protein_atlas_biological_process/basic/idx2term.json b/protein_atlas_biological_process/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e7aa6275f3faa941cbe4269d30cd05f995f4d9ff --- /dev/null +++ b/protein_atlas_biological_process/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Translocation", "1": "Transport", "2": "DNA recombination", "3": "Cholesterol biosynthesis", "4": "Spermatogenesis", "5": "Electron transport", "6": "Cholesterol metabolism", "7": "Sterol biosynthesis", "8": "Respiratory chain", "9": "Steroid biosynthesis", "10": "Sterol metabolism", "11": "Steroid metabolism", "12": "Hydrogen ion transport", "13": "ER-Golgi transport", "14": "Biological rhythms", "15": "Lipid biosynthesis", "16": "Ion transport", "17": "Protein transport", "18": "Growth regulation", "19": "Innate immunity", "20": "Apoptosis", "21": "DNA replication", "22": "DNA damage", "23": "Differentiation", "24": "tRNA processing", "25": "mRNA transport", "26": "DNA repair", "27": "Translation regulation", "28": "Antiviral defense", "29": "Glycogen metabolism"} \ No newline at end of file diff --git a/protein_atlas_biological_process/basic/plot_0.png b/protein_atlas_biological_process/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..02bae15a866ea99d5181aff0e94944be69b6164e --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1ace8596680543bccd0593b0f9fe29a0085907d516417bc1150d5a2d71edae0 +size 135886 diff --git a/protein_atlas_biological_process/basic/plot_1.png b/protein_atlas_biological_process/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..41cd58b981f4b6aa3fa68bf5a72fa9d6787ad15e --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd868fb10549a25b9a56b56f663489e978319a3f805380f3263781322310cb60 +size 134375 diff --git a/protein_atlas_biological_process/basic/plot_10.png b/protein_atlas_biological_process/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..53ef3ede6fd26dd21f69bf7faa93a4c195ef80db --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a418e990f0620cec2c24c985021bcd7d42a2b2dfc62d59fcea7764576e6d74d +size 134597 diff --git a/protein_atlas_biological_process/basic/plot_11.png b/protein_atlas_biological_process/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..d1959e90b80b97691a41f415b104e68704660372 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eac0f04cb1c927b501c92402fb47a6a03b5df6a1c497ffba8d1428dfd120f434 +size 134469 diff --git a/protein_atlas_biological_process/basic/plot_12.png b/protein_atlas_biological_process/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..fd28d750a3229f2a269e157820d8c868f5fe1b42 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10e12d58e9e6a25f371674121575a8e9331e0dcb54fe988bafb26c60b754cb70 +size 131471 diff --git a/protein_atlas_biological_process/basic/plot_13.png b/protein_atlas_biological_process/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..ee4b08b4b04ff57196f8ed1ec5d64cce4c8ee649 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f2d0f84d3385ea34986b017452cc757d3921fc10290a0af7f84135834751563 +size 138010 diff --git a/protein_atlas_biological_process/basic/plot_14.png b/protein_atlas_biological_process/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..3cb531836877bc6d956998d9721763242aee0821 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abc0432353fc4cc21150748f1e91a9cbf51408bc9e9d91b10989582bcf187a16 +size 141131 diff --git a/protein_atlas_biological_process/basic/plot_15.png b/protein_atlas_biological_process/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..2992b74d6baa9b8b024053463a46597c23e12dfb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29800852271bab8eee586227f39ebfdce0e5a44afe0a11edb78d6b2cd825e172 +size 133465 diff --git a/protein_atlas_biological_process/basic/plot_16.png b/protein_atlas_biological_process/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..3e2f0cd754b1685de27e5e1e8b4ea9641622b197 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ebd7b59af6d6d407ca40f8129b082dcb70a2204fc41c1d2b9c2f9501bc42d4b7 +size 131054 diff --git a/protein_atlas_biological_process/basic/plot_17.png b/protein_atlas_biological_process/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..95bc3918d8ba26e7c538b6e436ca32218639d488 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:adaa7cfd6d10255cd986f6cc70ec00d3c5e43dd634a0ffc6d3411360b276f6f4 +size 137706 diff --git a/protein_atlas_biological_process/basic/plot_18.png b/protein_atlas_biological_process/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..b3b23c4381d4dd72a02a6d0514f26ebe88fa5aa1 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c770cfd610ada55ea05384dd0919498d48f7cbe356004b50bb40a1d327dc2072 +size 134090 diff --git a/protein_atlas_biological_process/basic/plot_19.png b/protein_atlas_biological_process/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..3accab66867a27c7c51ab214938750dd5679e602 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a986eb4dfbde6f8b2dee12b1ea046d8299a97bb1c137d010e9560b5a5e050cd +size 143744 diff --git a/protein_atlas_biological_process/basic/plot_2.png b/protein_atlas_biological_process/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..10da0b9271e82ecb66d73afd99821b52b488fceb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02b5bbaa1e57b279b2d13301770fac41b68b8d839b7a1333480f6ed071719a26 +size 138418 diff --git a/protein_atlas_biological_process/basic/plot_20.png b/protein_atlas_biological_process/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..24e31018e527be15bd78ee10162d45bfaea0f2f9 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4f4f96fb04b9ea7e86f912643a11e13cf64848890297e11164e722b7a1c4591 +size 141061 diff --git a/protein_atlas_biological_process/basic/plot_21.png b/protein_atlas_biological_process/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..363b35ca189b7471536b09dd19c986100a768eb6 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ef337ef72c26d365138d8baace388ff7f79dd2a725008083422c19c858f8d67 +size 148238 diff --git a/protein_atlas_biological_process/basic/plot_22.png b/protein_atlas_biological_process/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..38afbf19cd239fcfcc465651ba23dc93be1989c5 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:87454660a1c1cb40d8937eba5fcb0063734e0d6f0a607b0462740fd2d454cc0e +size 141362 diff --git a/protein_atlas_biological_process/basic/plot_23.png b/protein_atlas_biological_process/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..8d166e61ad9b3d02f71dd4902133011a3917ae69 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16ba4a214fb3971fab80e0a7eefee8cc32122ee40d362b3eb13d511a3e90557c +size 139339 diff --git a/protein_atlas_biological_process/basic/plot_24.png b/protein_atlas_biological_process/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..9b87b7915dd36e012e2b3fff2bca60ca9d88c8ee --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14d905a0144ec677e54ded4cb7b39083a2d41423f78166bb65fd7518af02e1b9 +size 147986 diff --git a/protein_atlas_biological_process/basic/plot_25.png b/protein_atlas_biological_process/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..7c43cab0f9dab7f3d75aba8137d324fa21d28020 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a74f4623e21e90d3d9785fd36b952998001a083dcfdcfed24a842b0b11501d31 +size 144856 diff --git a/protein_atlas_biological_process/basic/plot_26.png b/protein_atlas_biological_process/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..332ee3f4dace69c70e0882677176d3aad8f4a272 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33a4a5f1b5bd9ff024b701bb490b4ee8769297089a9fc1947d9fff294ddd210b +size 140080 diff --git a/protein_atlas_biological_process/basic/plot_27.png b/protein_atlas_biological_process/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..181acfdbe46e45404a4bad44391a8469b92a412a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24200ceddb9dd3493da92454a0795a3ce8aaf050ea36ac96ef6f8b842a6c14f4 +size 146305 diff --git a/protein_atlas_biological_process/basic/plot_28.png b/protein_atlas_biological_process/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..75f0143709f65774541087281e4099ccd2361153 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2428c84bf3d3555f904ce8a371b38b29d89e353bea0b5b9e8a2b0ef8ed95c38 +size 147945 diff --git a/protein_atlas_biological_process/basic/plot_29.png b/protein_atlas_biological_process/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..eb80761543da81aa21e6e7b3fad41f0cc96a333b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53308412aed5b2189b70502f00fdcdfd9af583867452a22c21ac2a5d2aa62692 +size 144509 diff --git a/protein_atlas_biological_process/basic/plot_3.png b/protein_atlas_biological_process/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..28f8fd8551be7fc1352b964b010df7d720c7e3b8 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3d787727d811a79b9d5638c4b51e7bb340b3c5789bbd8a5f2917bfb676077d6 +size 130260 diff --git a/protein_atlas_biological_process/basic/plot_4.png b/protein_atlas_biological_process/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..037dbf47e54c8f508543c2d06e3dbd8d4d2c02a0 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ce99fb4db4a87bf0755fe051978cdc46e1cc792608cdf31c6490ad7127e88fa +size 140982 diff --git a/protein_atlas_biological_process/basic/plot_5.png b/protein_atlas_biological_process/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..98ad403d30b25b12882ed14380ea6c156910e3f9 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8340eb42c3bbb4dc37a478b9a06611a11cca5ee986c9abd55dbbda5eabe24e4 +size 136304 diff --git a/protein_atlas_biological_process/basic/plot_6.png b/protein_atlas_biological_process/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..fc73dd50ba31b829146fecbb0535d558c60d9273 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f58a8fa4186140169a30a4920babece8075aa1c34ed7a90384d5265463822a2 +size 133872 diff --git a/protein_atlas_biological_process/basic/plot_7.png b/protein_atlas_biological_process/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..d8d51f033a620835e68d20cb7baf14e74858e7d6 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d26d372bcdd38f2f5c38905ba79da3efc9b70cf2adb811ee08936fb8e22f2d8 +size 134072 diff --git a/protein_atlas_biological_process/basic/plot_8.png b/protein_atlas_biological_process/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..6eed5b754c96e6d9455e9c2b6893e163bc913268 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84dac13c80ae2cef6f4d2606facd696311430b3bdd51f6ab95d8691b2eb41d27 +size 129362 diff --git a/protein_atlas_biological_process/basic/plot_9.png b/protein_atlas_biological_process/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a98d6377aa88d022dc5f3ad5c7b1fa1ee6bd6510 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be2e6dd4515d96b749145a489e35fc8267c697f90ccedfc29999bf15bec13270 +size 132977 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..04246fd53199555e9ca4b9816779d45b92f06e61 --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0d763c34b51b493dc348d5154b71eb049cff5dfbdf52244fa201e2f44610e0f +size 95013 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed8203fe949ff36c9fe23f2055f4d2fb3ee21745 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Translocation 9 47 3.350362632099852 0.0008070582808787 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0047331978655521 0.005326863777972 1.0679246842113709e-05 5.1052272328632354e-05 +Transport 94 482 2.5033642773098728 0.0123018853368994 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 0.0006954652676638 0.0002602034919121 0.0001334881459523 0.0001760688725456 +Purine salvage 1 5 2.158709712562098 0.0308726948020734 1.203883495145631 4.978155339805825 0.7681087001497898 0.4029938560290594 1.3427925061534858 0.146176164319549 0.9596088570072956 0.304895906276926 1.0 0.0466801529674521 0.0055694485300755 0.0214944247869924 +Sphingolipid metabolism 3 9 2.100973489827512 0.0356432934462027 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 0.0033831948266032 0.0137871179019738 0.0762921742488627 0.0624183143373935 +DNA recombination 9 29 2.036344070662825 0.0417158173646299 8.327669902912621 24.12621359223301 -0.5816650137359928 0.528422147206057 4.006294974788614 2.9549353537208933 0.7502604026038592 0.3055638459132762 1.0 0.474050541733909 0.02289977346361 0.0014020336345134 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..be72c44ccfa45caa82a9dcb4505e80027515fe09 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 170, + "title": "Average number of proteins per term", + "value": 32.305882352941175 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a77735826722550b87cc1094eb06536c58110817 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eb93acdb1a9c80c77c3982842e78622f5239743f --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,57 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Translocation 0.5774529441432935 3.350362632099852 0.0008070582808787 0.1282523609485865 0.014486958365996 47 O60830,Q9Y5L4,Q99595,O43615,Q9Y5J9,P55735,Q5JVF3,Q9NS69,Q9BTX1 9 +GPI-anchor biosynthesis 0.8208420424007159 2.644045935484139 0.0081921537742817 0.75300864833926 0.0633030064376315 2 Q92643 1 +Biomineralization 0.7969543147208135 2.53193258985134 0.01134357967612 0.8562140432820382 0.0714225387014969 2 Q9UBB9 1 +Transport 0.3102702896673872 2.5033642773098728 0.0123018853368994 0.8780678553635046 0.0746900181168896 482 O60830,P24390,Q99595,O43678,Q70HW3,Q9H2D1,P35754,P49257,P83436,Q93050,O43676,Q5T1M5,O75964,P21796,Q9NS69,P08183,Q9Y282,P45880,Q9P0J0,Q96PU8,O95070,Q00169,O75695,Q09161,Q8TDB6,Q9UBX3,P22695,Q5JVF3,Q9BSK2,Q9Y5L4,P53007,Q13505,P53985,O43169,Q8IUD2,Q9BTX1,O43615,Q9Y5J9,Q8WUX9,P55735,O75381,Q13409,Q9Y487,Q9Y5K8,Q9HD20,Q9H1E5,Q9Y6C9,Q9UDW1,Q9P2W9,Q6P4A7,P18859,Q9UNH7,P12235,Q9Y3B3,Q96EE3,Q8NB49,P16615,Q96FJ2,O15127,Q8N4H5,P50542,P51970,O75306,Q6DKK2,O14828,O43681,Q9H089,Q8IWJ2,Q9UPT5,Q9Y2L5,Q08379,Q9UJ41,Q15036,Q9H3N1,P51572,Q7Z392,Q9H267,Q9P260,O60318,Q12846,Q9HC21,Q9Y5P4,P06576,P12270,P56134,Q86Y39,Q8NE01,Q9UM00,Q9Y4I1,O75380,P23786,P29373,Q9C0E2,Q8N1F7 94 +Purine salvage 0.8532555860476638 2.158709712562098 0.0308726948020734 0.9951611617945664 0.124960907532202 5 Q13126 1 +Sphingolipid metabolism 0.7602496328094671 2.100973489827512 0.0356432934462027 0.9979087311580584 0.1346524419078771 9 P07602,P04062,Q06136 3 +Polyamine biosynthesis 0.6954314720812222 2.039563126546543 0.0413938577988612 0.999243454148966 0.1477435198330643 2 P19623 1 +DNA recombination 0.5052344807347615 2.0363440706628255 0.0417158173646299 0.999285447139775 0.1477435198330643 29 P25490,Q15233,P26583,P15927,Q96EZ8,P09429,P16104,Q9UBU8,P27695 9 +Phagocytosis 0.7294248035789482 1.8679773339505297 0.0617652303408986 0.999980368252812 0.2019247914990917 3 P50570 1 +Cholesterol biosynthesis 0.5914018054816873 1.8221474875762 0.0684326099353391 0.9999941598074308 0.2195008243208992 16 P37268,Q13907,Q15126,Q15125,Q16850,Q15800,Q15392 7 +Spermatogenesis 0.4870681342944331 1.7514511978386116 0.0798682206004626 0.9999992846720458 0.2387299634658067 26 P46379,Q16181,Q14997,Q9Y4C1,P25490,Q9BY67,Q9P0K7,Q14141,Q9Y2W6,Q15019 10 +Electron transport 0.4068984027317632 1.7219861550144553 0.0850720265346247 0.9999997272441696 0.2435678528799072 47 Q6DKK2,O43678,Q9P0J0,Q9H3N1,P51970,O75380,O43676,Q9UDW1,P22695,Q86Y39,Q9H1E5,O43169,O75306 13 +Cholesterol metabolism 0.490335723526062 1.7109898127150347 0.0870829934390451 0.999999812362092 0.2435678528799072 25 P37268,Q15125,Q15126,P04062,Q16850,Q15800,Q15392 7 +Sterol biosynthesis 0.5337601635930922 1.702997193824192 0.0885685935540872 0.9999998577414984 0.2435678528799072 19 P37268,Q13907,Q15125,Q15126,Q16850,Q15800,Q15392 7 +Cell shape 0.741999731890602 1.682855390071565 0.0924030892199083 0.9999999305277236 0.2454457057403816 5 P15311,P35580,P35579 3 +Respiratory chain 0.4479919660953778 1.6537962937336146 0.0981689092828914 0.9999999764882688 0.2567494550475623 31 Q6DKK2,Q9P0J0,P51970,O75380,O43676,Q9UDW1,P22695,Q86Y39,O75306 9 +Steroid biosynthesis 0.4812594688333744 1.6435293294748683 0.100273462186569 0.999999984195158 0.2582801298744961 25 P37268,P54646,Q13907,Q15125,Q15126,Q16850,Q15800,Q15392 8 +Sterol metabolism 0.4591854986346327 1.6220713940638014 0.1047880623466182 0.9999999932795705 0.2632218786018203 28 P37268,Q15125,Q15126,P04062,Q16850,Q15800,Q15392 7 +Steroid metabolism 0.4530275104450311 1.6197371540206462 0.1052887514407281 0.9999999938892774 0.2632218786018203 29 P37268,Q15125,Q15126,P04062,Q16850,Q15800,Q15392 7 +Hydrogen ion transport 0.5162682412639756 1.5885621974495352 0.1121592684561156 0.9999999983519852 0.2750955319552076 19 P18859,P06576,Q9Y5K8,Q93050,O75964,Q9Y487 6 +ER-Golgi transport 0.3952365207315346 1.5779248288420895 0.1145828801954358 0.9999999989645108 0.2750955319552076 46 Q9Y282,P24390,P51572,P55735,Q9Y2L5,O95070,Q9P2W9 7 +Proline biosynthesis 0.6666433302900657 1.5765772111167298 0.1148928398165867 0.9999999990243474 0.2750955319552076 3 Q96C36 1 +Peroxisome biogenesis 0.6609916367980802 1.5500844031846506 0.1211212590455375 0.9999999997062872 0.2820632059964572 3 O43933,P40855 2 +Chromosome partition 0.488652519530811 1.5333524544480417 0.1251890367886869 0.9999999998665198 0.2841652231680858 22 Q96EE3,O76071 2 +Biological rhythms 0.3808611822497421 1.532630142744727 0.1253670102212143 0.9999999998710578 0.2841652231680858 50 Q09472,P43490,Q15233,Q14103,P42345,P54646,Q00839,O00429,Q8WXF1 9 +Lipid biosynthesis 0.3599395141901159 1.4424683057071803 0.149170306491077 0.9999999999988164 0.3209993937149757 57 Q6UWP7,Q96G23,P37268,Q9H7Z7,Q15125,Q15126,Q16850,P54619,P35790,Q96N66,Q15800,Q15392 12 +ATP synthesis 0.6313565075983751 1.3214470562454783 0.1863523447050763 0.9999999999999994 0.3727046894101526 7 P06576,P56134,O75964 3 +Sensory transduction 0.6500757197405238 1.2782074181116392 0.2011763012374177 1.0 0.3844015831573225 5 O60313,P50897 2 +Vision 0.6500757197405238 1.2782074181116392 0.2011763012374177 1.0 0.3844015831573225 5 O60313,P50897 2 +Ion transport 0.3617740508298228 1.2780110369585342 0.2012455347117747 1.0 0.3844015831573225 48 P18859,P45880,Q9Y5K8,Q93050,O75964,P21796,Q9Y487 7 +Protein transport 0.2715232659545649 1.1923386194452228 0.2331284973865954 1.0 0.4260542039419915 250 O60830,P24390,Q99595,O43615,Q9Y5J9,Q8WUX9,P55735,O75381,Q9NS69,O15127,Q8N4H5,P50542,Q9HD20,O95070,O14828,O75695,Q8TDB6,Q9H089,Q8IWJ2,Q5JVF3,Q9UPT5,Q9P2W9,Q9Y5L4,Q08379,Q9UNH7,Q9UJ41,Q9Y3B3,Q96EE3,Q13505,Q8IUD2,Q9BTX1 31 +Inflammatory response 0.5213815290870065 1.1191454159870888 0.2630781073499051 1.0 0.4610647242214832 12 P26583,P14174,P09429 3 +Growth regulation 0.4894582027220261 1.0147536114821305 0.3102232913767899 1.0 0.5321557471636704 13 Q5PSV4,Q9ULC4,Q13177,Q99816,Q9UBU8,Q92993 6 +Hearing 0.4929829799940309 1.0023737394428074 0.3161631203737101 1.0 0.5321557471636704 2 O60610 1 +Sodium/potassium transport 0.5376344086021374 0.9702485137570148 0.3319226340569035 1.0 0.5478334736861514 3 P54709,P05023 2 +Ubiquinone biosynthesis 0.4747685876381042 0.909876713556194 0.3628875317527633 1.0 0.5875321942663787 2 Q8NI60 1 +Glycogen biosynthesis 0.5700313007618432 0.8895422827196662 0.373711709625097 1.0 0.5993489682666651 4 P35573,P46976 2 +Chemotaxis 0.561096137809885 0.8520894537864647 0.3941644449197814 1.0 0.6213847283354625 4 P09429 1 +Transcription termination 0.5017065452164174 0.8059095770404252 0.4202949887294607 1.0 0.6323021954337019 3 Q9UNY4 1 +Innate immunity 0.2986847713274613 0.7792528942775406 0.435830757230887 1.0 0.6499230590285158 65 P14174,Q15233,P26583,Q8TDB6,P09429,Q8WXF1,Q15366,Q9BQ95 8 +Apoptosis 0.2836495447429371 0.7583115746334471 0.4482644797096771 1.0 0.660747489460576 130 Q9UDX5,Q9BY67,Q9UHX1,P51572,P21796,Q53EL6,Q6FI81,Q14185,P46379,Q9H0S4,Q9P0J0,Q13177,Q13043,O60313,P09601,Q9H2J4,Q96GX9,O95140,Q96F07,Q9BXK5,Q9NWH9,Q96A26,Q9NR28,Q13464,O14737,Q969H8,Q8WYA6,Q8NC60,P61289,Q96EY1,P17252,Q9NZJ7,Q9Y2J2,O60333,O95470,P27361,Q01085,P63167,P31483,Q14790 40 +Angiogenesis 0.4410384937842563 0.748640191479812 0.4540741007553652 1.0 0.660747489460576 13 P17252,Q9BXJ9,Q9H2J4,P35613 4 +DNA replication 0.2987188514339629 0.7475199868841829 0.4547497427463964 1.0 0.660747489460576 58 Q99741,Q04837,Q9BRT9,P25205,P28340,P15927,O60870,P51530,Q9BQ67,O95251,P35244,Q96RR1,Q9Y3Z3,P33991,Q9UBD5,Q14566,O43913,P33992,P54132,P35251,P09884,Q07864,Q8WVB6 23 +Calcium transport 0.5076177724474074 0.6953552330178221 0.4868327081910759 1.0 0.6772409544116358 6 P16615,Q9UM00 2 +DNA damage 0.2564631263491796 0.4570139599962922 0.6476610115285097 1.0 0.818860517143912 145 Q14997,Q9UQE7,Q15233,Q96FZ2,Q6PJG6,P28340,Q9ULC4,P15927,P13051,Q86WJ1,Q9UBU8,P51530,P27695,Q9Y2S7,P24941,P25490,Q8TDB6,O14757,P16104,P35244,Q99459,Q9HCS7,Q68E01,P18074,Q9H993,Q9NWY4,Q96EZ8,P09429,P54132,Q9UBZ9,Q96RU2 31 +RNA-mediated gene silencing 0.3376093919302073 0.4529964334949275 0.6505513096835078 1.0 0.818860517143912 20 Q9Y2W6 1 +Differentiation 0.2681973850279295 0.4445814503027084 0.6566222552151739 1.0 0.818860517143912 101 Q16181,Q86YR5,Q14997,Q9BY67,O00139,Q15019,Q00534,Q9BXJ9,Q14141,Q00839,Q96PU8,Q9Y2W6,Q7KZI7,P78362,P25490,Q96PU5,P16949,O96005,Q9P0K7,Q6NYC1,Q9Y4C1 21 +tRNA processing 0.2819570539131796 0.3301833926880076 0.7412613945493378 1.0 0.8937194118679959 34 Q2VPK5,Q12849,O15091,Q96PZ0,O60294,Q969Y2,Q9Y606,Q9BXR0,Q96FX7 9 +mRNA transport 0.2412812892066477 0.1701300470121904 0.8649078638647603 1.0 0.9925539950652182 66 Q09161,P55735,Q5JVF3,Q96PU8,Q9BTX1 5 +DNA repair 0.2424164022983884 0.1629633153859883 0.870547318577342 1.0 0.9925539950652182 128 Q14997,Q9UQE7,Q15233,P15927,P13051,Q86WJ1,Q9UBU8,P51530,P27695,P24941,P25490,Q8TDB6,O14757,P16104,P35244,Q99459,Q9HCS7,Q68E01,P18074,Q9NWY4,Q96EZ8,P09429,Q9UBZ9,Q96RU2 24 +DNA synthesis 0.3372693772811501 0.1274473200265731 0.8985863655986579 1.0 1.0 4 Q9UBZ9 1 +Antiport 0.3260662843118849 0.1128511112548967 0.9101485962007656 1.0 1.0 6 P51790,P12235 2 +Translation regulation 0.2371747351484814 0.1042685144281806 0.9169562635341624 1.0 1.0 48 Q09161,Q9BPZ3,Q96EY7,Q96PU8,Q92552,P27635,Q9H074 7 +Unfolded protein response 0.304589920367566 0.0917769688158575 0.9268752430414652 1.0 1.0 8 P55145,Q2TAL8,O95140,Q96CS3 4 +Antiviral defense 0.2410990304226782 0.0628514676711672 0.9498847815744018 1.0 1.0 29 Q9NUQ8,Q8TDB6,Q9H2U1,O14802,Q9Y3Z3,Q15366,Q7Z7L1,Q9NUD5 8 +Glycogen metabolism 0.269955156950683 0.0396253113740066 0.9683918477247077 1.0 1.0 6 P62136,P62140,P06737,P49841,P31751 5 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a4c9179b8ec09299c9e685e737c6c00256b47d26 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEX1", "API5", "APIP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMT1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "AUP1", "AURKA", "BABAM1", "BABAM2", "BACH1", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BEND3", "BIRC6", "BLM", "BMS1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CAMK1", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP6", "CASP7", "CASP8", "CBL", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC59", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPU", "CENPV", "CERS2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAO1", "CIAPIN1", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "COASY", "COG2", "COG7", "COL4A3BP", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRABP2", "CREBBP", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDHD2", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GINS1", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPR2", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GPSM1", "GRB2", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INCENP", "INPPL1", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRAK1", "IRF2BP1", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD5", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL3", "LAMC1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDLR", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGEA5", "MGME1", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MLH1", "MLLT1", "MMS19", "MND1", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NACC1", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFAT5", "NHP2", "NIP7", "NIPBL", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NME3", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPLOC4", "NPM1", "NR2F1", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NUBP1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXSM", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PANK3", "PANK4", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCA", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM23", "RBM25", "RBM28", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REL", "RELA", "REV1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RICTOR", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDHA", "SDHB", "SDHC", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SETD1A", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SON", "SORT1", "SPATA5", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TADA3", "TAF6", "TALDO1", "TAMM41", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TBK1", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TDP2", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLE3", "TLE4", "TLN1", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM14C", "TMEM214", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOLLIP", "TOM1", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPRKB", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT61A", "TRMU", "TROAP", "TROVE2", "TRRAP", "TRUB2", "TSC2", "TSFM", "TSG101", "TSR1", "TSR3", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC15", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGDH", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR5", "WDR6", "WDR61", "WDR75", "WDR92", "WIPI2", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YY1", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFP91", "ZMYM2", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCF3", "AGL", "AKT2", "APEX1", "APIP", "ARMT1", "ASNA1", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP5B", "ATP5J", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAG6", "BCAP31", "BCL2L13", "BLM", "BRAT1", "BRMS1L", "BSG", "CADM1", "CASP8", "CDC5L", "CDC6", "CDK2", "CDK6", "CERS2", "CHD1L", "CHEK1", "CHKA", "CHMP7", "CHTF18", "CIAO1", "CIAPIN1", "CLCN3", "CLPTM1", "CNNM3", "COG7", "COL4A3BP", "COQ8A", "CPT2", "CRABP2", "CTNNBL1", "CTU2", "CYB5B", "CYFIP2", "CYP51A1", "DDX47", "DHCR24", "DHX36", "DIABLO", "DIAPH1", "DNA2", "DNAJA3", "DNM1L", "DNM2", "DOCK1", "DTX3L", "DYNC1I2", "DYNLL1", "DYNLL2", "EBP", "ECSIT", "EP300", "EPB41L3", "ERC1", "ERCC2", "ERGIC3", "EXOC7", "EZR", "FAF2", "FAM162A", "FDFT1", "FKBP15", "GBA", "GCC2", "GINS4", "GLRX", "GOLGA2", "GPSM1", "GRSF1", "GRWD1", "GSK3B", "GTPBP3", "GYG1", "H2AFX", "HMCES", "HMGB1", "HMGB2", "HMOX1", "HNRNPD", "HNRNPU", "HPF1", "IDI1", "INTS3", "JMJD6", "KAT5", "KAT7", "KDELR1", "KDM3A", "KDSR", "KIAA0391", "KIAA1468", "KIF1B", "KIF2A", "KIN", "LCLAT1", "LCMT2", "LMAN1", "LSG1", "MANF", "MAPK3", "MARK2", "MBOAT7", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCRS1", "MCTS1", "MFN2", "MIF", "MORF4L1", "MRPS27", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTFP1", "MTOR", "MTX1", "MYDGF", "MYH10", "MYH9", "MYO5A", "NAA15", "NAMPT", "NCBP1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFB3", "NDUFS2", "NDUFS6", "NEDD4L", "NOA1", "NONO", "NUP93", "OPA1", "ORC3", "ORC5", "PAIP1", "PAIP2", "PAK2", "PCBP2", "PCID2", "PDCD4", "PDCD5", "PDCL3", "PEX1", "PEX14", "PEX19", "PEX5", "PIGK", "PITPNA", "PMVK", "POLA1", "POLD1", "POLDIP2", "POLE", "POLR3A", "PPP1CA", "PPP1CB", "PPT1", "PRKAA2", "PRKAG1", "PRKCA", "PSAP", "PSME3", "PSME4", "PSPC1", "PTCD3", "PTGES2", "PUF60", "PUS1", "PUS7", "PYCR2", "PYGL", "QKI", "QRICH1", "QTRT1", "RABGEF1", "RAI14", "REV1", "RFC1", "ROCK1", "RP2", "RPA2", "RPA3", "RPL10", "SAMHD1", "SCAMP2", "SCAMP3", "SEC13", "SEH1L", "SEPT2", "SEPT6", "SEPT7", "SFXN4", "SGPL1", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLFN11", "SLTM", "SMC3", "SNX17", "SNX6", "SRM", "SRPK2", "SSBP1", "STK4", "STMN1", "STX18", "STX4", "TDRKH", "TFIP11", "TIA1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM44", "TIMM8B", "TMCO1", "TMED7", "TMX1", "TMX4", "TOMM22", "TOMM5", "TPR", "TRAPPC11", "TRAPPC8", "TRMT61A", "TSG101", "TTC19", "TTF2", "TWNK", "UNG", "UQCR10", "UQCRC2", "USP28", "VDAC1", "VDAC2", "VPS33B", "XAB2", "XPO4", "YIF1A", "YY1", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0fd36c023034c991a08916c235155f026a681c2f --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/plot_0.png b/protein_atlas_disease_involvement/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e5065db3991722c7faaf9644fd41795eeddfb8d2 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2cf18fa86b6839294793f42f923cd8fe8eefe5b5dd001a7fe42843938845e6fa +size 220818 diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bf7eb21b27760b9e1142afa05ebe31133effdaeb --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "Cataract", "2": "Deafness", "3": "Leukodystrophy", "4": "Dwarfism", "5": "Obesity"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d7ddf71dac7e4b490ce1e41ba83c1a8fef54ffe6 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dcfe545710b1a3f07890bcd378bbf494f6ac86b35bd1b3e159d01d726ba2613e +size 147297 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5bec446503c22d2ce7b76ba9a7a8fd4e1cc620fa --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb879806b12cb5f8ce28ad9a392d4a57b1c36bfff3be98a8e06cfc204c03e67a +size 134266 diff --git a/protein_atlas_disease_involvement/basic/plot_2.png b/protein_atlas_disease_involvement/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..528f5283af52abf7b064ab821b899263304e48a6 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ca831873170dd0b646b06fa53f1e50ebfdcbdb0fe07a66f058a3b1897f77369 +size 139302 diff --git a/protein_atlas_disease_involvement/basic/plot_3.png b/protein_atlas_disease_involvement/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d3f573086170ae6a84b07deccca040af2b2b031a --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e10e70d5d35b7d3c510a309b6d480d0470fcca12deab7d51c69bdcc0c5f7747 +size 137175 diff --git a/protein_atlas_disease_involvement/basic/plot_4.png b/protein_atlas_disease_involvement/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..6319b4f13015eaad9a6b49b0105dbc3a8c5702e8 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba258fee48509599fb91cee8ac0fe49e20b3e70297f4eaf3b106acc3dabedb93 +size 138480 diff --git a/protein_atlas_disease_involvement/basic/plot_5.png b/protein_atlas_disease_involvement/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..11615376cd9d0ac3583e9f27a4b0a5ec93be9e80 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5196780d9f1e15008cad2eeba83016fa032947454d7d874f8b84404b6a6d55f9 +size 141149 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..62bba797a47a1977315f2751cbecfd23573290e3 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6134691451df8b03fa7e9155c8bda1067f7c4fa054e48dea64bcca59a6ee108 +size 84928 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..22dfc5f1384c2c343081d26d02570b557e88cff9 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 18 91 2.674151097515852 0.0074918688047678 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 0.0413944216471685 0.0051099064125164 0.0002060707296091 5.986586016885223e-05 +Limb-girdle muscular dystrophy 4 7 2.0239729050808357 0.042972939662627 2.4344660194174756 7.783980582524272 0.3462998769319207 0.5807492088335632 1.6686941747502206 1.3984858940080398 0.7510245178557768 0.292105742042388 1.0 1.0 0.4718643991127431 0.1309583783231107 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b2eba65a9ec2b02969de075679078abab187db63 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 115, + "title": "Average number of proteins per term", + "value": 23.16521739130435 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..065620adfb2f45d10ad004bc62f69223c7baa01d --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5fc9d3ad0724d624be6ff6fb1cf828c8b702f394 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,37 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Gaucher disease 0.9883547327560456 3.3913253438848057 0.000695554796589 0.0768990075055961 0.0266629338692451 2 P04062 1 +Kartagener syndrome 0.8417438041206127 2.7409753710801885 0.0061257099008156 0.5066927822060314 0.0546585993561343 2 P57076 1 +Primary mitochondrial disease 0.4327536676476999 2.674151097515852 0.0074918688047678 0.5788678034981403 0.0581585747334245 91 Q6DKK2,O75879,Q9HA77,Q9P0J0,Q00059,Q70HW3,O60313,Q9Y606,Q9UBX3,P14854,O43676,P22695,P12235,P51530,Q9BW92,Q6P4A7,Q9Y3D3,O75306 18 +Hirschsprung disease 0.8217378321887165 2.6482223827958498 0.0080916277889981 0.6071480316369199 0.0581585747334245 2 P42892 1 +Primary ciliary dyskinesia 0.826021799415644 2.3027386392112437 0.0212935527902513 0.915854351467478 0.1285073653157614 3 P57076 1 +Limb-girdle muscular dystrophy 0.7842805837567798 2.0239729050808353 0.042972939662627 0.9935984513872842 0.1830328911556337 7 Q5JTV8,P02545,O14979,Q7Z392 4 +Amelogenesis imperfecta 0.6775156763212934 1.9500950114752336 0.0511647957303957 0.9976180051135188 0.2003914778016664 2 Q6P4Q7 1 +Cockayne syndrome 0.7442457598250141 1.935842462056692 0.0528869985436433 0.9980671114317357 0.2003914778016664 3 P18074 1 +Zellweger syndrome 0.8088683209274098 1.912898037541292 0.0557611068665506 0.9986372481583417 0.2003914778016664 4 O75381,P50542 2 +Peroxisome biogenesis disorder 0.8088683209274098 1.912898037541292 0.0557611068665506 0.9986372481583417 0.2003914778016664 4 O75381,P50542 2 +Progressive external ophthalmoplegia 0.7804963003174046 1.7932996449086132 0.0729250241612833 0.99983472440575 0.2266588588796644 4 P51530 1 +Congenital myasthenic syndrome 0.7379149499178528 1.6117817032877682 0.1070094510361276 0.9999977746968118 0.2861880667245275 4 P53007 1 +Cataract 0.4325999325262195 1.409831011544813 0.158589587257214 0.9999999976236716 0.357603971266267 28 P18074,P08670,Q9H078,Q3LXA3,Q15125,Q15800 6 +Primary microcephaly 0.5725860877097646 1.3203614967302004 0.1867143523917276 0.9999999999523616 0.3639347546618419 11 Q2VPK5,Q86XL3 2 +Elliptocytosis 0.4888026276500513 0.9810438047061504 0.3265711403712856 1.0 0.5746036870207535 2 O60488 1 +Ciliopathy 0.501954921995597 0.8895282392443081 0.3737192534554521 1.0 0.6414584201101043 10 P57076,P49959,Q86Y56,Q01968 4 +Autism 0.5083830674067653 0.8360617875877022 0.4031201440983794 1.0 0.6573397328962232 3 P27635 1 +Ehlers-Danlos syndrome 0.4574499850701676 0.8232330093217419 0.4103755008360905 1.0 0.6573397328962232 2 Q96L58 1 +Non-syndromic deafness 0.4256617994565305 0.8177113703619323 0.4135220163491988 1.0 0.6573397328962232 16 P35241,Q9NR28,Q14651,Q9Y4A5 4 +Lissencephaly 0.4844087635828753 0.752701995225562 0.4516290107129641 1.0 0.6745108601557256 9 O00139,Q6ZXV5,P23258 3 +Corneal dystrophy 0.4150492684383418 0.6194206406103315 0.5356392870676869 1.0 0.7604755310220246 2 P37275 1 +Microphthalmia 0.4759004452416034 0.5654827621117648 0.5717454458219231 1.0 0.7921774249339898 6 P41227 1 +Xeroderma pigmentosum 0.4701537628882768 0.4937931014914864 0.6214523056105716 1.0 0.8126132685851858 4 P18074 1 +Deafness 0.2827449290615597 0.4868279826955385 0.6263802382702754 1.0 0.8126132685851858 49 P36776,P35240,Q15031,P51572,Q8N2K0,Q14651,Q9UG56,Q9Y4A5,Q9NSV4,O60313,P26358,O43933,Q9NR28,P51659,P49590,P19447,Q96RR1,P35579,P62266,Q15067,P35241,P18074,Q13217,O75648,Q13868,P49736 26 +Leukodystrophy 0.3456385989549472 0.4832869456139749 0.6288920078615785 1.0 0.8126132685851858 19 P07602,P20700,Q13144,P04350,P61960 5 +Oncogene 0.4060050410204564 0.409711918140862 0.6820172863088889 1.0 0.861889977203541 3 O43663 1 +Ichthyosis 0.39596340053928 0.3683992493163662 0.7125755571217902 1.0 0.8889471091383923 9 Q15125,P04062,P51648 3 +Ectodermal dysplasia 0.3977538583652115 0.3497475648875722 0.7265281536943871 1.0 0.8889471091383923 8 Q9H1A4 1 +Dwarfism 0.2608798227602871 0.3313928758207356 0.7403477454478791 1.0 0.8889471091383923 54 P18074,Q96PZ0,P48444,O75718,Q32P28,Q9NR45,P33992,P54132,P48651,Q15125,P19447,P51530,P62266,Q9UHB7,Q96HY6,Q9NUQ7 16 +Hereditary hemolytic anemia 0.3351062643632029 0.2771888328805789 0.7816351138822912 1.0 0.9266808051181804 14 P36551,Q8NB49 2 +Spinocerebellar ataxia 0.3497645456564974 0.2486734231032954 0.8036134084481199 1.0 0.943015734403406 11 Q9NXN4,Q8IV08,O14773 3 +Hypotrichosis 0.3578598038268491 0.1969353982702038 0.843878092268938 1.0 0.9504548044371096 7 Q9H1A4,Q8IWS0 2 +Cushing syndrome 0.359127576934565 0.1691991931691149 0.8656399643990165 1.0 0.9571980375566048 4 O00170,P10644,P40818 3 +Dystonia 0.321535586324118 0.1049126178028509 0.916445146665478 1.0 0.9942565270427356 6 P51572,P04350 2 +Emery-Dreifuss muscular dystrophy 0.2779438135086594 0.0498297095647246 0.9602580912754493 1.0 1.0 5 P02545,Q13642,Q8WXH0,P50402 4 +Obesity 0.2023916292974681 0.007867440095161 0.9937227557717898 1.0 1.0 6 Q9BW83,P41091,Q9Y4W2,Q9C0B1,Q9UHB7 5 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a5493c2096a6aef6c80924173b9b16cbf9ad6ece --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG9", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARSA", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCLAF1", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN5", "CARM1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT5", "CD320", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CENPF", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHM", "CHMP1A", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLIC1", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "COA7", "COASY", "COG2", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDHD2", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC2", "DSG2", "DSP", "DST", "DTNA", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF2S3", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIBP", "FIP1L1", "FKBP10", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFM2", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPD1L", "GPHN", "GPI", "GPT2", "GRB2", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD11", "HPRT1", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGF2R", "IGHMBP2", "IKBKB", "ILF3", "ILK", "IMPA1", "IMPDH1", "IMPDH2", "INF2", "INPP5K", "INPPL1", "INTS1", "INTS8", "IPO7", "IRF2BPL", "IRS4", "ISCA2", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LAMC1", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIMD1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARS", "MATR3", "MBD1", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MESD", "MFN2", "MGA", "MGAT2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MLH1", "MLLT1", "MMAB", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEK9", "NF1", "NF2", "NHLRC2", "NHP2", "NIPBL", "NME1", "NME2", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDHA1", "PDHB", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP1R21", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB27A", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD54B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "REL", "RELA", "REPS1", "RFC1", "RFC2", "RFK", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "SAMHD1", "SARS", "SART1", "SASS6", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHAF2", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC39A14", "SLC3A2", "SLC5A6", "SLC9A3R1", "SMAD4", "SMARCA4", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF6", "TALDO1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBK1", "TBL2", "TCEA1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM199", "TMEM43", "TMTC3", "TMX2", "TNPO3", "TNRC6B", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TPRKB", "TPX2", "TRAF2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFM1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNG", "UPF3B", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VAC14", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP2", "WDR1", "WDR11", "WDR26", "WDR36", "WDR4", "WDR45", "WDR5", "WDR73", "WFS1", "WIPI2", "WNK1", "WRAP53", "XIAP", "XPC", "XPNPEP3", "XPO1", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "YY1", "ZC3H14", "ZCCHC8", "ZEB1", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ABHD12", "ACOX1", "ACSL4", "AFF4", "AIP", "ALDH3A2", "ANAPC1", "ANKLE2", "ARCN1", "ATP11C", "B3GALT6", "BCAP31", "BLM", "C21orf59", "CARS2", "CLPB", "CNNM4", "COX6B1", "CPOX", "CRTAP", "CTU2", "DDRGK1", "DIABLO", "DIAPH3", "DNA2", "DNAAF5", "DNAJC3", "DNMT1", "EBP", "ECE1", "EIF2B5", "EIF2S3", "EMD", "ERCC2", "ERCC3", "EXOSC2", "FHL1", "FTO", "GATB", "GBA", "GDAP2", "HARS2", "HNRNPDL", "HSD17B4", "IFT27", "KIF2A", "LARS2", "LAS1L", "LMNA", "LMNB1", "LONP1", "MCM2", "MCM5", "MRE11", "MRPS16", "MSMO1", "MYH9", "NAA10", "NANS", "NDUFA13", "NDUFB3", "NDUFS2", "NF2", "OCRL", "OPA1", "P3H1", "PEX1", "PEX14", "PEX5", "PHF6", "PISD", "PLD3", "PLS1", "PRC1", "PRKAR1A", "PSAP", "PTDSS1", "PUS1", "PUS7", "RDX", "RPL10", "RPS23", "SFXN4", "SLC25A1", "SLC25A10", "SLC25A26", "SLC25A4", "SYNE2", "TARS2", "TFAM", "TKFC", "TMTC3", "TOR1AIP1", "TPP1", "TRAPPC11", "TRMU", "TRRAP", "TTC19", "TUBB4A", "TUBG1", "TWNK", "UFM1", "UFSP2", "UQCRC2", "USP8", "VIM", "ZEB1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..77dba4eaa978d1d21475dbd90c88c24e05e8b7aa --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosyltransferase", "2": "Dioxygenase"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/plot_0.png b/protein_atlas_molecular_function/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..563d74e2f7d208dbe99050061ba21abca480a49e --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60226a3a34030cf259d6e1a5c069c96365effea2d0d442bc00a011127c3c39bd +size 207690 diff --git a/protein_atlas_molecular_function/advanced/plot_1.png b/protein_atlas_molecular_function/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..467024fc565805d3d472a197b05067791303810f --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f843ee5c5c89cdc72db0b09b881aa196f266ed7186e0c9ae49e8d0240a972582 +size 201548 diff --git a/protein_atlas_molecular_function/advanced/plot_2.png b/protein_atlas_molecular_function/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..993d97700dd15f6d76e792357b426255005ff408 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c17f2f50eb3df0037944eca232b7b50271c19dc09daddc2dcaade978fc55362 +size 195191 diff --git a/protein_atlas_molecular_function/basic/idx2term.json b/protein_atlas_molecular_function/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cec6ca73d65cefa1ec434fabb0be2b0a07c3af5b --- /dev/null +++ b/protein_atlas_molecular_function/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosyltransferase", "2": "Dioxygenase", "3": "Motor protein", "4": "Ribonucleoprotein", "5": "Translocase", "6": "Oxidoreductase", "7": "Initiation factor", "8": "Ribosomal protein", "9": "Aminoacyl-tRNA synthetase", "10": "Methyltransferase", "11": "Serine/threonine-protein kinase", "12": "Acyltransferase", "13": "Nucleotidyltransferase", "14": "Transferase", "15": "rRNA-binding", "16": "Kinase", "17": "Tyrosine-protein kinase"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/plot_0.png b/protein_atlas_molecular_function/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e50d7d103b8be2add09553315b0ca12322e6ad04 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f8dfdc1290dc63b2634b71c0e83c5da05133a9f7ef82253b258f2b1fa57dc36 +size 134605 diff --git a/protein_atlas_molecular_function/basic/plot_1.png b/protein_atlas_molecular_function/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5a3c27dc4e2694e6425fa39943974fd2ff84cabc --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e83220a66cee322c210d2572aeb5d2f7709ff58446bca76a7c6a4b8a6460a73e +size 144190 diff --git a/protein_atlas_molecular_function/basic/plot_10.png b/protein_atlas_molecular_function/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..ad97f9ca2f64cd594a3e4cd22ab6f238cd20be59 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:797472bde658bf8395ece6be6f6c57a05d5d094b8fb0812f51c9913274ef7366 +size 149168 diff --git a/protein_atlas_molecular_function/basic/plot_11.png b/protein_atlas_molecular_function/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..bbb0dbbaf9660aef2dd12e3c0a67cfd289651b1f --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b5b8af1743cfe9174b0183ca37289a0f9b3f4ab23a20bfc20d3852f740dc297 +size 151003 diff --git a/protein_atlas_molecular_function/basic/plot_12.png b/protein_atlas_molecular_function/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..2ef9b07eac99f2f80b8cb1e67ce7b539e62a43d1 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c62afb0038428fba75033d8ed8935fd9091c59665f7f16c3e60baa0b5baab9d +size 145431 diff --git a/protein_atlas_molecular_function/basic/plot_13.png b/protein_atlas_molecular_function/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..5e9f2d18c7c243de01c59afbb81d2d7c0205b239 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:456ccfed688b47aa73086bf69c90bd85d9176f9cdd7539667da541057d167bb3 +size 145841 diff --git a/protein_atlas_molecular_function/basic/plot_14.png b/protein_atlas_molecular_function/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..30e88c9e04f10e3238a3d3dae56fe3de936df34c --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b80762cee99cd0e64cd623c385198370a5e1b3c12619435fe5c91134b63f98e0 +size 138169 diff --git a/protein_atlas_molecular_function/basic/plot_15.png b/protein_atlas_molecular_function/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..ac669409a9f5d86c3b4a62d6da47aa664ec39016 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe80ecf053fdef103d5eb0b99681fb9c1155ed8ecc6b9f413b97ff36b89ca140 +size 142149 diff --git a/protein_atlas_molecular_function/basic/plot_16.png b/protein_atlas_molecular_function/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..f4bb87577ddc7c73ff06a66489e9f5e49d76fdf9 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1822a99e59a5e1d915a384dfd640c6ab59e2d42cb7c92c09436b030b0706fd2d +size 142302 diff --git a/protein_atlas_molecular_function/basic/plot_17.png b/protein_atlas_molecular_function/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..1e696c796d43917064ad1f5062b2d58ce05d2603 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:378b1607c0f1de14ef777e26378ca028453bed089cd8491170d4ac7dfbdfe7e6 +size 145026 diff --git a/protein_atlas_molecular_function/basic/plot_2.png b/protein_atlas_molecular_function/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d698a172d08f1d86f09fa10ff7c9b4677de7e702 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1acf6a1af7ab8b40916e1d4d2b425eae1629b3e2e08f131807c3025aa00ab3c5 +size 131592 diff --git a/protein_atlas_molecular_function/basic/plot_3.png b/protein_atlas_molecular_function/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..79dc118e67e6b67d9a35a5e4f7329f2e4d132538 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4619913a5105b5b57737d9cfbd3c600be0d19b8afd1e13643055dca9702cb46f +size 132183 diff --git a/protein_atlas_molecular_function/basic/plot_4.png b/protein_atlas_molecular_function/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3e993d0333d471fe18845001e56eddbe86671a65 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41ac6097d3790662a6a79eddf3690ca6667d9113a4c5c70f7c1fcee44a5e4bb3 +size 140933 diff --git a/protein_atlas_molecular_function/basic/plot_5.png b/protein_atlas_molecular_function/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..4348556f0742846fd1e5ffd2bb7a4e8978c052d7 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cebb22a13ee1cc5636b4bba07677abd9a122788ebd78b6afd2a0baf98e6d7172 +size 132971 diff --git a/protein_atlas_molecular_function/basic/plot_6.png b/protein_atlas_molecular_function/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..b37cf1b8ff4dea2f2cf3c0bc66011b8b2a205d6d --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9413f2d9a25483daba861e39f5303fa8a2541a3b650413e7640e7c92924656ba +size 142413 diff --git a/protein_atlas_molecular_function/basic/plot_7.png b/protein_atlas_molecular_function/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fca39b5377b656ca7ab80eb7def7b860600bcf5f --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c49c66979d82b2cb0eac272f3fa895bb5d65d8d173c2858fdae821efa839b988 +size 143457 diff --git a/protein_atlas_molecular_function/basic/plot_8.png b/protein_atlas_molecular_function/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b733e8c8b09b0606843dccb6a8ff1509368645d4 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf53e54548d063fb758182172eedbbf6535ab6be30e4868679ff2279540b6f8d +size 146954 diff --git a/protein_atlas_molecular_function/basic/plot_9.png b/protein_atlas_molecular_function/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4fb9dbb56bad4fbf93a2658e7ecca72558e72c7b --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:afd715e36191e5e43aa901201553c237d4bbcff809289a0fd47069139522996e +size 152199 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3c3bbefd469698581d42a401ccc19dc642fdbd20 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91767ab78bee0c7bc8f2ab45f38ede0a7151a7286761ae7021a2879d4c91ff6b +size 81846 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2f28bcc5c93d0d3224e9d58e6716690591c785de --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Receptor 6 36 2.828041156529681 0.0046833785098217 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.005639897207451 0.031771963204952 0.4028997659297014 0.7833935360557607 +Glycosyltransferase 9 39 2.345752603086097 0.0189887066893814 8.383495145631068 33.63106796116505 0.9005425082235603 0.4380439374186179 3.633517034002208 4.6602851932859135 0.9766631781348049 0.3531801259598526 0.1040786659520682 0.104205851680364 0.5537530520072641 0.3606228290403846 +Dioxygenase 6 18 2.111868211394797 0.0346977546342075 4.485436893203883 16.929611650485437 0.3291673001296444 0.5856007381165738 2.3948329397108954 3.0857324105273336 0.8401407542250483 0.3144845391083291 0.2497294948713996 0.1174994317391053 0.1896820159952031 0.0804683260329309 +Muscle protein 3 5 1.9762236046745607 0.0481294575881605 2.395631067961165 5.79126213592233 0.1338245975855889 0.4297267356278353 1.4112173151187923 1.0428309859537837 1.1380106971522683 0.3003044609278026 0.0841142186818086 0.1662183776826317 0.0102137155300364 0.0624183143373935 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..367e9b38353f2582cf9275f9ac9736a027c4c19a --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 42.385416666666664 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d92ddcacc130678d1caa36456675c92c5064dde9 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..05331c079bcc1e814e6b3a7bce8912f3d482a51c --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Monooxygenase 0.9471484025082072 3.213593216436523 0.001310852402669 0.1183184854847542 0.0157302288320284 2 Q9BU89 1 +Receptor 0.5681381194883711 2.8280411565296815 0.0046833785098217 0.3627928432120751 0.0345849489956064 36 O15173,P24390,Q9NS69,P35613,Q14108,Q8WTV0 6 +Porin 0.9657849396634366 2.550675661934154 0.0107514328128119 0.645740690628512 0.0688091700019967 4 P21796 1 +Cytokine 0.9233504162961126 2.3823774180574815 0.0172012577767033 0.8109394868934525 0.1012731023433678 4 P43490 1 +Glycosyltransferase 0.4966323233640793 2.345752603086097 0.0189887066893814 0.8412533136149728 0.1012731023433678 39 Q10472,P43490,O60568,P35573,P04062,Q13126,Q9H6U8,Q9BXR0,Q2TAA5 9 +Dioxygenase 0.6121866602208141 2.111868211394797 0.0346977546342075 0.9662962384362292 0.1753149707833644 18 O60568,Q32P28,Q8IUF8,Q9NWT6,Q6NYC1,O00625 6 +Muscle protein 0.8100383800280775 1.9762236046745607 0.0481294575881605 0.9912203512401674 0.2259026019893976 5 P06753,Q03001,P67936 3 +Motor protein 0.4737438477526975 1.929810727888213 0.0536302937703732 0.9949668524023244 0.2340231000889012 33 Q9Y4I1,Q9Y6G9,P35580,Q9Y496,P33176,O60333,Q9H0B6,Q96FJ2,P35579,P50570,O43237,P63167,Q13409,O00139,Q9BW19,O95235,Q9NS87 17 +Actin capping 0.752910316455158 1.787731065370222 0.0738194072188187 0.9993649835919212 0.274861947671528 6 P35241,P52907,P47755,Q13813 4 +DNA-directed DNA polymerase 0.6965352449223349 1.7160461099187865 0.0861536033763248 0.9998246815765202 0.2945180411567876 3 P28340,P09884 2 +Host cell receptor for virus entry 0.5495829570420835 1.4385549475632415 0.1502766587227171 0.999999837578086 0.4243105658053189 14 Q14108,P35613 2 +Ribonucleoprotein 0.2809580741513683 1.4045215514006602 0.1601635986961151 0.9999999471931004 0.4283603866716963 188 Q92665,P62841,Q9Y4Z0,P09132,Q9UHX1,Q9H2W6,Q9P015,Q96EY7,Q9BUJ2,Q14103,P31942,P61254,Q16540,P62081,P46778,Q00839,Q15366,Q96HR8,P50914,O60506,P82933,P08865,P25398,P84098,P49458,P62917,Q96A35,P62899,P55769,P46782,P61513,O76094,Q02543,P62753,P15880,Q7Z7H8,Q92552,P46776,Q8WVV9,P27635,O43390,Q9Y3D3 42 +Translocase 0.4520633504682476 1.197154546580071 0.2312463225434675 0.9999999999891463 0.5045374310039292 20 Q9HD20,P16615,Q8NB49,P08183,O75306 5 +Oxidoreductase 0.2627963481782566 0.9639604004908858 0.3350657796926308 1.0 0.6701315593852617 178 P36551,P30519,Q32P28,Q9BU89,P09601,Q6IAN0,Q9Y6N5,Q8IUF8,Q16850,Q9UHG3,Q709F0,P53004,Q8NBX0,O00625,P00374,Q15800,Q15392 17 +Endonuclease 0.3849167535820681 0.7745873486353199 0.4385835353939435 1.0 0.72222400500823 21 P51530,Q9Y2C4 2 +Prenyltransferase 0.5402091745579161 0.7656798215224156 0.4438668364113081 1.0 0.72222400500823 4 P49354 1 +Initiation factor 0.3068617087221249 0.5914960115222991 0.5541881267650728 1.0 0.8184932333761075 39 P46199,Q9ULC4,P41567,P55010,P20042 5 +Myosin 0.4380169203296743 0.5411777774994553 0.5883850530888854 1.0 0.8387140800566045 9 Q9Y4I1,P35580,O94832,P35579 4 +Ribosomal protein 0.2666250702588892 0.4519156299256288 0.6513297641240299 1.0 0.9061979326943024 121 Q92665,P62841,Q9H2W6,Q9P015,Q96EY7,P61254,Q16540,P62081,P46778,P50914,P82933,P08865,P25398,P84098,P62917,Q96A35,P62899,P46782,P61513,Q02543,P62753,P15880,Q7Z7H8,Q92552,P27635,Q9Y3D3 26 +Aminopeptidase 0.3679944903959643 0.3161130272737409 0.7519167190352751 1.0 0.9284274417205228 11 P53582 1 +Aminoacyl-tRNA synthetase 0.2805042539500275 0.3105068651883735 0.7561755396473253 1.0 0.9284274417205228 33 P54136,P49591,Q9HA77,Q9Y285,P49589,A2RTX5,P41250,P23381,P49590,Q5T160,P47897,Q9BW92 12 +Methyltransferase 0.2596996125172122 0.3066707356383018 0.7590940067025467 1.0 0.9284274417205228 52 Q9BV86,Q86TU7,P04818,O60294,Q9H993,P21964,O14744,Q99873,Q8N4J0,Q96FX7,O60725 11 +Serine/threonine-protein kinase 0.2529893089427019 0.2875522053697577 0.7736895347671024 1.0 0.9284274417205228 71 Q13464,P78362,Q13177,Q13043,P24941,O15111,P36507,P42345,Q00534,Q13555,P54646,O14757,P27361,Q16512,P17252,Q7KZI7 16 +Acyltransferase 0.2584243361522342 0.1867173582118061 0.8518822455626653 1.0 0.98084605729113 36 Q09472,Q6UWP7,P23786,O60318,Q86UY6,Q96N66,Q92993,P41227 8 +Nucleotidyltransferase 0.2731681790964353 0.1800851718187574 0.857085703470156 1.0 0.98084605729113 25 Q8NFF5,P28340,O00411,O14802,Q9UBZ9,Q9Y5P6,P09884,P30876,Q16851,Q9BWH6 10 +Nuclease 0.2538529245360795 0.1700276817718622 0.8649883667030398 1.0 0.98084605729113 38 P51530,O15091,P27695,Q9Y2C4 4 +Transferase 0.2249007491405824 0.1569917692568528 0.8752513348481972 1.0 0.98084605729113 411 P43490,O15269,O95376,P34897,Q13555,P04062,Q8N4J0,Q16512,P49354,P28340,Q13043,O15111,P21964,P42345,O14744,Q96CB9,Q13126,Q9BXR0,Q9BWH6,Q8NFF5,P42356,O00411,Q8TDB6,Q96PU5,P35573,O94874,P48426,O60725,Q9Y673,Q7LGA3,Q96G23,Q5VTR2,O43708,P14373,Q15126,P19623,Q96N66,Q3LXA3,Q00534,P37268,P55263,Q9BV86,P78362,P41227,P04818,Q7Z6K3,O15344,Q86UY6,O60568,Q6ZXV5,P35790,Q92993,Q6UWP7,Q9H6U8,Q7KZI7,P24941,P36507,Q99873,P17252,Q9H993,Q9UBF8,Q9UBZ9,Q10472,Q09472,P46976,O75390,Q96FX7,Q2TAA5,O60318,P54646,Q9Y3D8,Q86TU7,P12277,O14757,P48651,O60294,P23786 77 +rRNA-binding 0.2799212689108552 0.1526496192718495 0.8786745929899706 1.0 0.98084605729113 19 Q96EY7,P62917,Q7L8L6,Q96CB9,Q92552,P62750,P62913 7 +Kinase 0.234855395380748 0.0699565328628593 0.9442282565829052 1.0 1.0 126 P04183,Q13555,Q3LXA3,P35790,Q16512,P12532,Q13177,Q13043,Q00534,O15111,P42345,P54646,P55263,Q7KZI7,Q9Y3D8,P42356,Q13464,P78362,P24941,P12277,P36507,P48426,O14757,P17858,P17252,Q99570,Q9UBF8,Q15126,P27361 29 +Tyrosine-protein kinase 0.2662473794549211 0.040364501884032 0.9678025305648792 1.0 1.0 12 P45985,Q15375,P46734,P36507,Q02750,P33981,Q9UIG0,P19525,O14733,P07947,P49760 11 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b07876597cdc5f5e49b75f856cecacbab5729892 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMPD2", "ANKHD1", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APIP", "APLP2", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "AS3MT", "ASAH1", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BBX", "BCAT2", "BCKDHB", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C11orf54", "CAD", "CADM1", "CALD1", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHKA", "CHM", "CHMP1A", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CKB", "CKMT1A*", "CLGN", "CLIC1", "CLIC4", "CLK2", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CROT", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DACH1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "EMD", "EMG1", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS8", "ERAL1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPSM1", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS11", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT5", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD3", "LEO1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAEA", "MAGED1", "MAGED2", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MATR3", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP3", "NCL", "NCOA5", "NCOR1", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFAT5", "NHP2", "NIFK", "NIP7", "NIPBL", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM7", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB27A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAI1", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REL", "RELA", "RETSAT", "REV1", "REXO4", "RFC1", "RFC3", "RFK", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHAF2", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SH3RF1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TMCO1", "TMEM109", "TMOD3", "TMTC3", "TNRC6B", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSN", "TSR3", "TST", "TSTA3", "TTF2", "TTK", "TUFM", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRFS1", "UROD", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YY1", "ZADH2", "ZBTB10", "ZC3H13", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZEB1", "ZFP91", "ZFR", "ZMPSTE24", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZZZ3"], "leading_proteins": ["ABCB1", "ACAD11", "ADK", "AGL", "AK6", "ALG11", "ALG5", "ALG9", "APEX1", "ARIH2", "ARMT1", "ATP11C", "ATP13A1", "ATP2A2", "BAZ1B", "BLVRA", "BSG", "CAMK2G", "CAPZA1", "CAPZA2", "CARNMT1", "CARS", "CARS2", "CDK2", "CDK6", "CERS2", "CHEK1", "CHKA", "CHUK", "CKB", "CKMT1A*", "CLK2", "COMT", "CPOX", "CPT2", "CS", "CYP51A1", "DHCR24", "DHFR", "DHRS7B", "DNA2", "DNM2", "DOHH", "DST", "DTX3L", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EIF1", "EIF2AK2", "EIF2S2", "EIF5", "EP300", "EPHA7", "EXOG", "FARSA", "FASTKD5", "FDFT1", "FLAD1", "FNTA", "GALNT1", "GARS", "GBA", "GMPPB", "GSTZ1", "GYG1", "HARS2", "HIF1AN", "HMOX1", "HMOX2", "HNRNPD", "HNRNPH3", "HNRNPLL", "HNRNPR", "HNRNPU", "HNRNPUL1", "HS2ST1", "ICMT", "JMJD6", "KAT5", "KDELR1", "KIAA0391", "KIF15", "KIF1B", "KIF20A", "KIF2A", "KIF3A", "KIF5B", "KIFC1", "KLC2", "LCLAT1", "LCMT2", "LSM4", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAPK3", "MARK2", "MBOAT7", "MCM3AP", "MCTS1", "METAP1", "MID1", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSMO1", "MTAP", "MTIF2", "MTOR", "MYH10", "MYH9", "MYO1D", "MYO5A", "NAA10", "NAA40", "NAF1", "NAMPT", "NDUFS2", "NEDD4L", "NSUN4", "NTMT1", "P3H1", "PAK2", "PCBP2", "PCYOX1", "PFKL", "PGRMC2", "PI4KA", "PI4KB", "PIK3R4", "PIP4K2A", "PIR", "PKN1", "PLOD3", "PMVK", "POLA1", "POLD1", "POLR2B", "POLR3A", "POLRMT", "PRKAA2", "PRKCA", "PRMT1", "PRMT5", "PTAR1", "PTCD3", "PTDSS1", "PUF60", "QARS", "QTRT1", "RARS", "RARS2", "RDX", "REV1", "RIOX2", "RNF20", "ROCK1", "RPAP1", "RPL10", "RPL11", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL23A", "RPL26", "RPL27A", "RPL31", "RPL37A", "RPL8", "RPS12", "RPS15", "RPS2", "RPS5", "RPS6", "RPS7", "RPSA", "SARS", "SCARB1", "SCARB2", "SCCPDH", "SETD3", "SHMT2", "SNU13", "SPTAN1", "SPTLC1", "SQOR", "SRM", "SRP19", "SRP72", "SRP9", "SRPK2", "STK4", "SYNCRIP", "TARS2", "TARSL2", "TK1", "TKFC", "TMTC3", "TOMM22", "TPM3", "TPM4", "TRIM27", "TRMT61A", "TTK", "TYMS", "UFL1", "UGP2", "VDAC1", "WARS", "YES1"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d9d884224d4041b280400220e138a0d4558cc814 --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d83f48f2397c3f7d5f0a267131f07dcd489488fe --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ccc0a6ac10f9d6000acd8d43de3d3826519cff2df9e7b02e8ac0d9a0a7123c0 +size 228714 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0e68bcf56612123b6e7c73dd86216aa1181f02f2 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b01541af329e8c834d2bd4c1c139b25d178573c420838d89f7786026bb0cfe48 +size 223560 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d28ef4b3b4c1a7f453d393f352db105e78e121f2 --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "Predicted secreted proteins", "3": "Ribosomal proteins", "4": "Potential drug targets", "5": "Transcription factors"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8fc3b97b46998c3c8c33157c5b0cb7ce3d6f348b --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:edbcec0814719cb29ac10429a0d99939ab2aaa19c3fd0245d8c9907f9c8c74f2 +size 144171 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a14ad4506f9ab9f8935dfd3ec17c2bb2e125afe0 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60dde05d47ea57c1de9462f189a9baefd55e269f5a8fe22c16fed5394d62ee71 +size 138802 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..4639f2afcefe0383b16b1a5288aed74beff078da --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c82b73dbe511591412f172d922e8eb7e6d1080a4b85d3101f954866329c48c5 +size 137220 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f2999bd3b8bf50f7c032037bed83d1f182590e3f --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:945f5e7401a6a256c05f74cfd0955e57e9d60cb9b9a84f13306888947cba0644 +size 148513 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..87019cffcc0b51cce236b89d836e77b48a53d505 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8fce937708c75f6d24464c7ca45de3573c33f96e65ac73849dcd7da9e0643d4 +size 140038 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..136e7f493ddb5ed2e6fa41545d0923fd2e155502 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:845709758f003f9ce2e07edd3447d0c0b3b24e183a72ab8027c6a6e943b6ef45 +size 145450 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..4d840821e0759118ffcb562252240291b576ab32 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47994c46c92bee6080c387789036ec37d353cf4041f6d51b099bec8df1c7f3bb +size 89713 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3db55bbd4d217a99f3b15587921b8ec355426f70 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 123 508 4.443895375987823 8.834457775552806e-06 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.0012233257419165 0.0043240029790186 0.0001611483098298 0.0097430999340836 +Transporters 70 340 2.623665427476701 0.0086989189616675 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 0.0008299490050875 0.0065895773060854 0.0060295958676345 0.0019245349984334 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..75a978a67d865e9ec44c32be496f7074e9e3832f --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 509.2857142857143 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2f806a74b3f751150fe0679f45ff37205f28ee1b --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d393ae9356577f46fdee407adf248072d4b7797e --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.3796861140798669 4.443895375987823 8.834457775552806e-06 0.0001855072241983 9.276180664331496e-05 508 O60830,P24390,Q99595,P30519,Q70HW3,Q93050,O43676,Q567V2,O75964,Q9NS69,P35613,Q14108,Q8NBX0,P08183,Q8WTV0,Q15392,Q9Y282,Q9P0J0,P09601,Q5BJF2,Q9HD45,O95070,Q9Y2W6,Q9BWH6,O15173,P36551,Q9UBX3,Q4G176,Q9H061,Q9BSK2,O60725,Q6UW68,Q96G23,Q8TBA6,Q8TCT9,Q8NCG7,O00264,Q92544,Q96N66,Q70UQ0,Q13505,P53985,O43169,Q9BTX1,Q9UDX5,Q86XL3,Q6IAN0,Q14789,O75381,P33908,Q9Y487,Q15800,Q96PV6,P37268,Q9NVH1,Q9NVA1,Q9HD20,Q16850,Q07065,Q9H1E5,Q96A26,Q9NR28,Q96KC8,Q9Y6C9,Q9UDW1,Q06481,Q9UBD5,Q9P2W9,Q6P4A7,O43760,P12235,O15344,Q9Y3B3,Q8NB49,P38435,P16615,Q8IY95,Q9Y4J8,P67812,Q15125,Q6ZXV5,O15127,Q9NZC3,Q6UWP7,A1L0T0,Q9H6U8,Q96TA2,Q9H1A4,Q9UNN8,O75306,O14828,Q8IV08,Q9UPR3,Q14534,Q5SNT2,P51648,O96005,Q8N511,Q9P0I2,Q9ULE6,Q10472,Q9H3N1,Q9BY67,Q52LJ0,P51572,P42892,O75390,Q2TAA5,Q9P260,Q5SWX8,P54646,Q12846,Q9HC21,O75448,P48651,P56134,Q86Y39,Q8NE01,Q9UM00,Q86UP2,Q06136,Q53GQ0,Q5JTV8 123 +Transporters 0.3093975981042158 2.6236654274767015 0.0086989189616675 0.1676285502599716 0.0456693245487545 340 P24390,Q70HW3,Q15006,Q9H2D1,Q9H3N1,P09132,Q8N1F7,P49257,Q93050,P51572,Q6ZXV5,P55735,O75381,P50570,P40855,P35613,Q14108,O15127,P08183,Q8WTV0,Q12959,P45880,P07602,O60313,O95067,Q9HD20,O60318,P54646,Q5BJF2,Q12846,Q07065,Q8TAT6,Q9HC21,Q9UG63,O14828,O43681,Q09161,Q9Y6C9,P12270,Q9UBX3,P49458,O00429,Q9UPT5,Q9H061,Q9BSK2,Q8NE01,Q6P4A7,Q9UM00,O96005,Q6UW68,Q9C0E2,P53007,Q8TBA6,Q9NPI6,Q8N511,Q9P0I2,P12235,Q9UJ41,Q92544,Q9Y3B3,Q96EE3,Q15036,Q96N66,Q8NB49,Q96A33,P53985,P16615,Q8IY95,Q9Y4J8,Q9BTX1 70 +Predicted secreted proteins 0.3603834186805478 1.1536060458538564 0.2486617185665736 0.997530859176478 0.6527370112372557 42 P43490,P14174,O60568,O60888,Q8IW92,P26583,P80303,P09429,Q15165,Q02818,Q9HB40 11 +Candidate cardiovascular disease genes 0.4583370855307465 0.6317246967401212 0.5275667872524399 0.99999985507315 1.0 9 Q9UNN8,Q15165 2 +Ribosomal proteins 0.2630659155680369 0.4364307965439575 0.6625241988947956 0.9999999998760932 1.0 128 Q92665,P62841,Q9H2W6,Q9P015,Q96EY7,P61254,Q16540,P62081,P46778,P50914,P82933,P08865,P25398,P84098,P62917,Q96A35,P62899,P55769,P46782,P61513,Q02543,P62753,P15880,Q7Z7H8,Q92552,P27635,Q9Y3D3 27 +RAS pathway related proteins 0.2986651018656999 0.4319188774832565 0.665800374079808 0.9999999998990456 1.0 32 P36507,O15111,P17252,Q13043 4 +CD markers 0.3414408343948235 0.3853830015463079 0.6999536746519031 0.9999999999895056 1.0 17 P35613 1 +Potential drug targets 0.237485512085136 0.3604539662690307 0.7185076757099234 0.9999999999972534 1.0 506 O15269,Q70HW3,Q9H2D1,Q32P28,P23381,P49257,Q13555,P04062,Q14108,Q15392,P07099,Q13043,P07602,O15111,P09601,Q13126,P53004,P14174,P36551,Q96PU5,P22695,Q4G176,Q9H061,P53007,Q8TBA6,P50897,Q15126,Q96N66,P53985,Q3LXA3,O75381,Q15800,Q9HA77,P37268,P51530,P55263,Q10713,P00367,O00429,Q9BW92,Q6P4A7,P41227,P51159,O15344,Q8NB49,Q9Y4J8,Q9NUQ7,O60568,Q15125,Q6ZXV5,O95630,O60313,Q9H6U8,Q96TA2,Q4J6C6,O75306,Q8IV08,P53701,P51648,P18074,Q8N511,Q9Y606,P63000,Q01968,Q09472,Q6P3W7,P51572,P50570,P46976,P42892,P40855,Q2TAA5,P13051,O60318,Q08426,Q9HC21,Q12873,P12270,P48651,Q9UM00,P33992,P54132,Q06136,Q96A33,Q8N1F7 85 +Transcription factors 0.2542859295603439 0.3039454036224904 0.7611694860117462 0.999999999999913 1.0 72 P67809,Q96KC8,Q00059,P25490,Q15233,Q9BQ70,O95251,Q99459,Q8WXF1,Q969G3,Q01664,Q99543,P17096,Q9UIS9,Q92993,Q8IVW6,Q8WXI9 17 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d3ba6c4c21f24faf90ab51b2ce74c9b935c07957 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf54", "C11orf98", "C12orf57", "C15orf39", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C21orf59", "C2CD5", "C5orf15", "C5orf24", "C7orf26", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARNMT1", "CARS", "CARS2", "CASK", "CASP6", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPU", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP3", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG2", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPP5K", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MLH1", "MLLT1", "MMAB", "MMS19", "MND1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R21", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB27A", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDHA", "SDHAF2", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM214", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6B", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROAP", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPYL1", "TSR1", "TSR3", "TSSC4", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCF2", "ACSF3", "ADK", "ALDH3A2", "ALG11", "ALG9", "ANAPC1", "ANKLE2", "APLP2", "ARID3B", "ASNA1", "ATP11C", "ATP13A1", "ATP2A2", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "BCAP31", "BLM", "BLVRA", "BSG", "CADM1", "CAMK2G", "CARS2", "CCDC47", "CCNB2", "CDC5L", "CERS2", "CHD3", "CHUK", "CKAP4", "CLPTM1", "CNNM3", "CPOX", "CS", "CUTA", "CYB5B", "CYP51A1", "DAGLB", "DCP1A", "DHCR24", "DHRS7B", "DIABLO", "DLG1", "DNA2", "DNAJC1", "DNAJC11", "DNAJC2", "DNM1L", "DNM2", "DTNA", "EBP", "ECE1", "EHHADH", "EMC2", "EMC3", "EP300", "EPHX1", "ERCC2", "ERGIC3", "EXOC7", "FAM162A", "FAM98B", "FDFT1", "GALNT1", "GATAD2B", "GBA", "GDE1", "GGCX", "GLB1L2", "GLUD1", "GOLGA5", "GOLGB1", "GYG1", "HCCS", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HSD17B12", "ICMT", "IKBIP", "ILVBL", "KAT5", "KAT7", "KDELR1", "KDSR", "KIAA1468", "KTN1", "LCLAT1", "LENG8", "LMAN1", "MAN1A1", "MAP2K2", "MBD1", "MBOAT7", "MCM3AP", "MCM5", "MED24", "MID1", "MIF", "MPV17L2", "MRPL10", "MRPL15", "MRPL23", "MRPL24", "MRPL46", "MRPS16", "MRPS27", "MRPS31", "MRPS9", "MSMO1", "MTAP", "MTCH2", "MTFP1", "MTX1", "NAA10", "NAMPT", "NCBP1", "NDC1", "NDUFA11", "NDUFA13", "NDUFB3", "NDUFS2", "NEDD4L", "NONO", "NPLOC4", "NUCB1", "NUCB2", "NUP93", "OCRL", "ODR4", "OPA1", "ORC3", "P3H1", "PALD1", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PLD3", "PLOD3", "PMPCA", "PMVK", "PON2", "PPT1", "PREPL", "PRKAA2", "PRKCA", "PROCR", "PSAP", "PSPC1", "PTCD3", "PTDSS1", "PUS1", "RAB27A", "RABGEF1", "RAC1", "RPAP1", "RPL10", "RPL14", "RPL18A", "RPL19", "RPL21", "RPL26", "RPL31", "RPL37A", "RPL8", "RPS12", "RPS15", "RPS2", "RPS5", "RPS6", "RPS7", "RPSA", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SCYL2", "SEC11A", "SEC13", "SEH1L", "SFXN4", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SMARCE1", "SMG5", "SNU13", "SNX17", "SPTLC1", "SQLE", "SRP19", "SRP9", "STAMBP", "STK4", "STX18", "STX4", "SYNGR2", "TARS2", "TCF25", "TDRKH", "TFAM", "TFAP4", "TIMM17A", "TIMM17B", "TKFC", "TM9SF3", "TM9SF4", "TMCO1", "TMED7", "TMEM126A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM97", "TMTC3", "TMX1", "TMX4", "TOMM22", "TOR1AIP1", "TPR", "UFSP2", "UNG", "UQCC1", "UQCR10", "UQCRC2", "VDAC2", "WARS", "XPO4", "YBX1", "YIF1A", "YME1L1", "YY1"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5e886d2af5bf757e821a3be931005c58463adc14 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondria"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6bc683ac7cf37622cc44ade27bd377deee18e9fd --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:04c6a7b1f6eafda1526591097655207f14ea115127ad46d6cfa005cc813d8e03 +size 222325 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5dad8a668291030ba183345b3b009c8c2939a9ef --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondria", "1": "Vesicles", "2": "Endoplasmic reticulum", "3": "Golgi apparatus", "4": "Microtubules", "5": "Intermediate filaments", "6": "Actin filaments", "7": "Plasma membrane", "8": "Centrosome", "9": "Lipid droplets", "10": "Nucleoli fibrillar center"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3f4f488e6f5a2bbb9bc2acece443f24c363bda82 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9767bbc0427443ae153e3a3079d10004f9a65524d07104ec84a5089c721b03da +size 138177 diff --git a/protein_atlas_subcellular_location_all/basic/plot_1.png b/protein_atlas_subcellular_location_all/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7f4d319670fadca3f80405be90ba03aeeba4318d --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c582284171fdd4e692d2440526f98b0efe4a4c88d6740076ea34fbbc7651d22 +size 134318 diff --git a/protein_atlas_subcellular_location_all/basic/plot_10.png b/protein_atlas_subcellular_location_all/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..72978f56170c9999014b1aa469818d4648e60a5e --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc1bbef9a2b5448eff961b067fc94709e9a0aa87b9d2a1739caccf31717fc989 +size 148307 diff --git a/protein_atlas_subcellular_location_all/basic/plot_2.png b/protein_atlas_subcellular_location_all/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5944b8445cdd0e52898c5a55cdd87110a960bb78 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ddc0a5919fd61348c2df4b6b5e340006069ebbc88e60a5a2519979035030089b +size 140396 diff --git a/protein_atlas_subcellular_location_all/basic/plot_3.png b/protein_atlas_subcellular_location_all/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..e2d408465ed87001e6967de96684237f821e57ea --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f69e952f6a17d49e6e271f2ce0bfbd972f8f5759d756f26b5d603e82caee8c9 +size 143152 diff --git a/protein_atlas_subcellular_location_all/basic/plot_4.png b/protein_atlas_subcellular_location_all/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..48ab50767194a093d2fd3b12853be763d1a263ad --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d02a63a4ce9cae45a1f65642e64fa3174dc2e535bf09b0fae49210ceb6b9b1e9 +size 136310 diff --git a/protein_atlas_subcellular_location_all/basic/plot_5.png b/protein_atlas_subcellular_location_all/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..d5f49078420627056f8281adad84bf3534302ae6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab795044d14bcc8b03f400ca8496309e3dc2d178b3846d9e77fe80921ddffbf4 +size 147871 diff --git a/protein_atlas_subcellular_location_all/basic/plot_6.png b/protein_atlas_subcellular_location_all/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..024f0fb70ae1741f6037e3bcd97a5f7c461dea14 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8617016dedc8bb677bee2540ea4f9c5fcfb959d7a2f38a60d9738b62317016d +size 146598 diff --git a/protein_atlas_subcellular_location_all/basic/plot_7.png b/protein_atlas_subcellular_location_all/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..69fc55fb9babe8bedcbc8bced5d5dc340cc44e0f --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f185423a643a3b7d18a5873b84c8c138bb03d1703acb288ee9bc305d753f3249 +size 142838 diff --git a/protein_atlas_subcellular_location_all/basic/plot_8.png b/protein_atlas_subcellular_location_all/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..f7d452d5d4b6cf356c2e3e8b421ce07f08c9bf3d --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b57415a8aa11087d07b64950b7b9923e317a48f799e44b081e45304a44fda9a +size 142868 diff --git a/protein_atlas_subcellular_location_all/basic/plot_9.png b/protein_atlas_subcellular_location_all/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..1bc982e429bd699eb4c28aa92e052e332f487d67 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:feb576740c71ae1958c90ef5adb7d94091010e283231f840cbf29cb9b7e2bf7a +size 134439 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3445514ecb4f79843f534e0a6e67e128f87f9db5 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de7eb9b2c0d0d10d1a6e6618543e1d204e8f85a34d37f107d4c262cb7b36f4ce +size 76520 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d84649b5027836b46e389a77e90e85ab9e2e358a --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Mitochondria 60 400 2.9269200981495507 0.0034233681858499 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 0.0004235933703053 5.098986638866724e-05 2.659980135723598e-07 5.060581816394154e-07 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..45e74cfcf94010d1bebedbeeec9d533154958523 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3351, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 157.6969696969697 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..512ba9580f0cbb06639cc414d13b5f74615f184c --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C120/C120_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1c2f58f3297a3f29a2208441e97acec3367e9d2e --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,17 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondria 0.3249870156850271 2.9269200981495507 0.0034233681858499 0.1069966649996976 0.0564855750665247 400 O60830,Q9UDX5,Q92665,Q8N5C6,Q99595,O43615,Q70HW3,Q9Y2C4,Q9H2D1,Q96BK5,Q9NUJ1,Q9H2W6,Q96EY7,O75964,Q9NS69,Q04837,O75879,P00374,P46199,P45880,Q9HA77,Q9P0J0,Q8N4H5,Q5T9A4,P51970,Q9H7Z7,Q9NVH1,O60313,Q16540,Q96C01,Q96TA2,P51530,Q10713,Q96A26,O75306,Q2VPK5,Q9NR28,Q6DKK2,P36551,O15091,Q00059,P00367,Q6P3X3,Q9Y6C9,Q9UBX3,Q9H0B6,Q9Y6N5,P22695,Q4G176,Q6P4A7,Q4VC31,Q969Z0,P18859,Q9Y5L4,P14854,P12235,Q7Z7H8,Q8WVV9,Q13505,Q9Y3D3 60 +Vesicles 0.2798492632099749 1.8946470713794703 0.0581391742150509 0.8614641352226878 0.4796481872741707 309 P24390,P67809,P30519,Q9H0A8,Q32P28,Q15075,Q9BPZ3,Q93050,Q52LJ0,P55735,P46976,P35613,Q5M775,Q99996,Q8NBX0,Q9Y487,Q8WTV0,O15127,Q92993,Q12959,Q9NZC3,Q7Z392,Q9NWV4,Q14254,P07602,Q9HD20,A1L0T0,Q9HD45,O75153,O95070,Q9H1A4,Q96JB5,Q00169,O14828,Q9NRY5,O14981,Q13576,P25490,Q13595,P25398,O14757,P42785,O00429,Q9HCS7,Q9UPT5,Q06481,Q14534,P30043,Q6P4A7,P61758,Q8IW92,P50897,Q9UNF0,Q15036,Q8IUD2,Q13813 56 +Rods & Rings 0.681221065638052 1.4674052707434653 0.1422658415365871 0.9936811318820168 0.7624168078691698 6 Q8WTV0 1 +Endoplasmic reticulum 0.279358423780807 1.3594901197596374 0.1739913312319208 0.99817823660953 0.7624168078691698 192 Q96CN7,P67809,O15269,Q15293,P62841,Q9H3N1,Q13017,Q86XL3,P49257,P55145,Q15125,P51572,P35790,P30533,Q13409,Q96CS3,Q15800,Q96HY6,Q6UWP7,P37268,P21964,O43852,P61254,P62081,Q5BJF2,P46778,Q16850,Q96F07,Q9H6U8,Q14257,P50914,Q96KC8,O94874,P51571,Q8IV08,P48651,P62917,Q9P2W9,Q9UBS4,P46782,P51648,Q9UM00,O96005,Q6UW68,Q86UP2,Q96G23,Q8TCT9,P61513,O00264,P62753,P15880,P43307,P46776,P27635,Q96A33,Q70UQ0,P20042,O43169 58 +Golgi apparatus 0.2817628338172162 1.3260343581019227 0.1848283170591926 0.998821797871548 0.7624168078691698 177 P24390,Q96BK5,Q86YR5,P67812,Q93034,P83436,Q93050,Q14789,P50570,P33908,Q99996,Q96SU4,Q9HB40,O15127,Q02818,Q9Y4A5,Q9NRG1,O14795,P50542,O95067,P09601,A1L0T0,P54646,Q9HD45,O95070,Q9Y5P4,O00231,O43290,P25398,Q8IWJ2,O43760,Q08379,O75122,Q8TBA6,P80303,P50897,O15344,Q9UBF8 38 +Microtubules 0.3332410134816977 1.110910367140493 0.2666069326186804 0.99996401558793 0.9775587529351616 55 O60830,Q9NWY4,Q03001,Q9Y2L5,Q13409,P04350,P55209,Q13813,Q01968,O75330 10 +Lysosomes 0.4893622286383327 1.0142175517124894 0.3104789553085407 0.999995300319348 1.0 13 Q8WTV0,Q9UNH7 2 +Endosomes 0.4387419682848139 0.6794310286926799 0.4968647951511309 0.9999999998569146 1.0 12 Q9P2R3,Q9UNH7 2 +Cell Junctions 0.3041520461598882 0.6536718678175326 0.5133232314870395 0.9999999999522536 1.0 46 P53985,P43490,Q9H2W6 3 +Intermediate filaments 0.3081549681028074 0.5859580774008607 0.5579036873887424 0.9999999999979952 1.0 38 Q86U06,O14795,Q9UJX5,O75718,P08670,Q99471,P07197,Q9Y4J8 8 +Actin filaments 0.2779975760749874 0.4696061460475622 0.6386364328161145 0.9999999999999974 1.0 51 Q05682,Q16181,P35580,P82664,P12814,Q15019,P67936,Q9UI12,Q6P4Q7,Q9NVA1,O75607,O75718,P06753,P35579,Q9NYL9,Q6WCQ1,Q9P0K7,Q9P0V9,Q9UL03,Q9BTX1 20 +Peroxisomes 0.3197327110002154 0.2162232200726571 0.828813754630904 1.0 1.0 14 P40855,O75381,O15254 3 +Plasma membrane 0.213457771058291 0.1758284761440122 0.8604286974171318 1.0 1.0 312 Q05682,Q16181,P35754,Q13555,Q9UQB8,Q16512,P08183,Q9ULC4,P09601,Q99816,Q96F07,Q9Y5M8,O15173,Q8NFF5,O75695,P42356,O43663,P53582,P48426,Q9H7E9,Q9NNW5,Q9Y2J2,Q8NCG7,P62136,P53985,Q8IUD2,Q9BTX1,P67809,Q86XL3,Q9H2M9,Q6IAN0,Q9UNZ2,Q9Y487,Q15019,P12814,Q12959,Q9Y263,P15311,Q6P4Q7,Q9NVA1,Q4KMQ2,Q16763,Q92888,Q99747,P55263,Q9NPQ8,Q66K14,Q9NZM3,A0MZ66,Q9UKS6,Q9H0B6,Q9P2W9,P35241,P26038,P35240,P31948,O95630,Q9NZC3,P50579,Q7KZI7,Q9UPT5,Q14166,P17252,O60888,Q9BR76,Q9UNF0,Q9H0A8,Q96CT7,Q5SWX8,Q14254,Q12846,Q13576,P08865,P30043,Q9UJZ1,P46939,Q86TV6,Q9H074 78 +Centrosome 0.2399208811163033 0.1662913484086101 0.8679276742261486 1.0 1.0 74 Q9UJW0,Q3YEC7,Q9Y2W6,P24941,Q8N8E3,Q8WYA6,Q9BSJ2,O75330,O00139,Q99996,Q9BRT9,Q13561,Q9Y3D8 13 +Lipid droplets 0.3245283807464433 0.1413241589001448 0.8876138651061489 1.0 1.0 9 Q8NBQ5,Q969V3,P08397,Q96CS3,Q969E2 5 +Nucleoli fibrillar center 0.2314069737246603 0.0857597846380134 0.9316573758614456 1.0 1.0 68 Q9Y5L4,P25490,Q15233,Q16540,Q8WXF1,O75381,Q5M775,Q66K14 8 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2923b272fd780d32c0d9ca399c7d440529db8ccc --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ADAR", "ADD1", "ADD2", "ADD3", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG2", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOOL", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC1", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARSA", "ARVCF", "AS3MT", "ASCC2", "ASCC3", "ASF1A", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG16L1", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BABAM1", "BABAM2", "BACH1", "BAG2", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BAZ2A", "BBX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf54", "C12orf57", "C15orf39", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD5", "C5orf15", "C5orf24", "C7orf26", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPN7", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP6", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC7", "CDC73", "CDCA2", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPU", "CENPV", "CEP112", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP1A", "CHMP5", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK2", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COG2", "COG7", "COIL", "COL4A3BP", "COLGALT1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX4I1", "COX5B", "COX6B1", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRABP2", "CREBBP", "CRKL", "CROT", "CRTAP", "CRYZ", "CRYZL1", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DACH1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH1", "DDAH2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DTL", "DTNA", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP300", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "EPS8", "ERAL1", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIBP", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFM2", "GFPT1", "GGA1", "GGA2", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPSM1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIC2", "HIF1AN", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT5", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3A", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "L3MBTL3", "LACTB2", "LAMC1", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LYPLA2", "MACF1", "MACROD1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGAT2", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIOS", "MIPEP", "MKI67", "MLH1", "MLLT1", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NF2", "NFAT5", "NFATC2IP", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSRP1", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD5", "OTUD7B", "OTULIN", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHACTR4", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS4", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R21", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTAR1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REV1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASEH2A", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRN3", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTKN", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHAF2", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPK", "SHTN1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCAL1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQOR", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOML2", "STRAP", "STRIP1", "STRN", "STRN3", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAGLN2", "TALDO1", "TAMM41", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIPRL", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLE4", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMEM109", "TMEM115", "TMEM126A", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM214", "TMEM97", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPYL1", "TSR1", "TSR3", "TSSC4", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL7", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC13B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC2A", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR44", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR74", "WDR77", "WDR82", "WDR92", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRNIP1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YY1", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZEB1", "ZFC3H1", "ZFP91", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF207", "ZNF24", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABHD10", "ACOX3", "ACSF3", "ACTN1", "ADK", "AK6", "AKAP9", "ALDH3A2", "ALG9", "ANAPC1", "ANAPC4", "ANKFY1", "ANKLE2", "ANO6", "APLP2", "ARHGAP5", "ARHGEF1", "ATAD3B", "ATP13A1", "ATP5J", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1H", "BAIAP2", "BCAP31", "BLVRB", "BSG", "BTAF1", "C1orf123", "C8orf33", "CALD1", "CALU", "CAMK2G", "CARS2", "CCDC124", "CCDC47", "CCDC58", "CCNB2", "CDK2", "CDK5RAP3", "CEP112", "CERS2", "CHEK1", "CHKA", "CLASP2", "CLPTM1", "CLUH", "CNNM4", "COG7", "COL4A3BP", "COMMD4", "COMT", "CORO1B", "COX6B1", "CPOX", "CRTAP", "CTNNBL1", "CTU2", "CUL5", "CUTA", "CYB5B", "CYFIP2", "CYP51A1", "DAGLB", "DCTN2", "DCTN4", "DDRGK1", "DHFR", "DHRS7B", "DIABLO", "DLG1", "DNA2", "DNAJB11", "DNAJC1", "DNAJC11", "DNM1L", "DNM2", "DST", "DTNA", "DYNC1I2", "EBP", "EEA1", "EIF2S2", "EPB41L3", "ERC1", "EXOC7", "EXOG", "EZR", "FAF2", "FAM114A2", "FAM136A", "FAM162A", "FAM98B", "FDFT1", "FLAD1", "FLOT2", "GATB", "GCC2", "GDE1", "GINS4", "GLB1L2", "GLRX", "GLUD1", "GOLGA2", "GOLGA5", "GOLGB1", "GPSM1", "GYG1", "HM13", "HMBS", "HMMR", "HMOX1", "HMOX2", "HNRNPLL", "HPF1", "HSD17B11", "IKBIP", "ILVBL", "INTS6", "IQGAP2", "ISOC1", "ITSN2", "KAT5", "KDELR1", "KIAA0391", "KIF2A", "KLC2", "KTN1", "LCLAT1", "LMAN1", "LRPAP1", "MAN1A1", "MANF", "MARK2", "MCTS1", "METAP1", "METAP2", "MID1", "MPRIP", "MRPL10", "MRPL23", "MRPL46", "MRPS10", "MRPS16", "MRPS31", "MSMO1", "MSN", "MTCH2", "MTFP1", "MTIF2", "MTX1", "MYH10", "MYH9", "NAMPT", "NAP1L1", "NAPG", "NCLN", "NDC1", "NDUFA13", "NDUFA8", "NDUFS2", "NEFM", "NF2", "NONO", "NPM3", "NSFL1C", "NUCB1", "NUCB2", "OCRL", "ODR4", "OPA1", "OSBPL9", "P3H1", "PACSIN2", "PACSIN3", "PAIP1", "PAIP2", "PEX14", "PEX19", "PEX5", "PFDN5", "PGRMC1", "PGRMC2", "PI4KA", "PI4KB", "PINX1", "PIP4K2A", "PITPNA", "PKN1", "PLAA", "PLD3", "PMPCA", "PPP1CA", "PPT1", "PRC1", "PRCP", "PRKAA2", "PRKCA", "PRTFDC1", "PSAP", "PSMD11", "PSPC1", "PTCD3", "PTDSS1", "PTGES2", "RAB3GAP2", "RABL6", "RAI14", "RBM23", "RCN1", "RCN2", "RDX", "RIC8A", "RP2", "RPL10", "RPL14", "RPL21", "RPL26", "RPL27A", "RPL37A", "RPL8", "RPS12", "RPS15", "RPS2", "RPS5", "RPS6", "RPS7", "RPSA", "SART1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCCPDH", "SCPEP1", "SEC11A", "SEC13", "SEPT10", "SEPT2", "SEPT7", "SFXN4", "SHTN1", "SLC16A1", "SLC25A10", "SLC25A26", "SLC25A32", "SLC25A4", "SNX17", "SNX6", "SPECC1", "SPTAN1", "SPTLC1", "SQLE", "SQOR", "SRBD1", "SRPRB", "SSBP1", "SSR1", "SSR4", "STAMBP", "STIP1", "STOML2", "STX18", "STX4", "SYNGR2", "TBC1D9B", "TBRG4", "TDRKH", "TFAM", "TIMM13", "TIMM17A", "TIMM17B", "TIMM44", "TM9SF3", "TMCO1", "TMEM205", "TMEM97", "TMOD3", "TMX1", "TOMM22", "TOMM5", "TPM3", "TPM4", "TRA2A", "TRAPPC11", "TRAPPC8", "TRRAP", "TSG101", "TTC19", "TTC27", "TTC7B", "TTLL12", "TUBB4A", "TUBGCP2", "UBE2S", "UFL1", "UNC13B", "UQCC1", "UQCRC2", "UTRN", "VBP1", "VDAC2", "VIM", "WDR6", "XAB2", "YBX1", "YIF1A", "YME1L1", "YY1"]} \ No newline at end of file