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c2c9cff verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Neutrophil degranulation 0.7011048814099864 3.4987215030094796 0.000467494601881 0.4830396599917986 0.1305666306403289 169 Q4KMQ2,Q08722,P07858,P07602,Q9UBR2,O75874,P06280,P10253,P15586,P04066,P11717,Q01469,P17900,P53634,P61916,O15260,O00754,O00560,Q92820,P42785,P04439,Q9BTY2,P10321,P08236,P16278,P11279,P10619,P01889,Q92542,P07686,Q13510,Q99519 32
Sphingolipid metabolism 0.8325584746388346 3.320247881471749 0.0008993755273565 0.7190531781795036 0.1305666306403289 29 P16278,P17900,P07602,P06280,P10619,Q13510,Q9Y5P4,Q8NBJ7,P07686,P06865,Q99519 11
Trans golgi network vesicle budding 0.7432438354250316 3.148121359393131 0.0016432345599821 0.9017766251357242 0.1305666306403289 40 Q9UBR2,P15586,O75976,Q99523,P11717,P05067 6
Glycosphingolipid metabolism 0.9113251133205752 3.013997755929555 0.0025782971303149 0.9738177929968496 0.1305666306403289 17 P16278,P17900,P07602,P06865,P06280,P10619,Q8NBJ7,P07686,Q13510,Q99519 10
Extracellular matrix organization 0.7677777464054388 2.9234509099019963 0.0034617480607659 0.992501112300705 0.1320142301011009 27 Q08722,P07858,P35613,Q9Y624,O14936,P12814,Q92542,P05067,P05556 9
Diseases of metabolism 0.6801711410540097 2.8924207067365257 0.0038228566529938 0.9955031918368616 0.1385434565635574 47 P08236,P16278,P54802,O75874,P10619,P10253,P15586,Q9NPF0,P07686,O43505,P06865,Q99519 12
Mhc class ii antigen presentation 0.6458860939991102 2.7595006857043143 0.0057889765644991 0.9997231349814188 0.1496388690788519 56 Q9Y6B6,P53634,P07858,Q9BUF5,Q99538,P10619,P55735,Q13409,Q9H0H5,Q9BVA1,Q9UQ16,Q02241 12
Cell surface interactions at the vascular wall 0.851378736825563 2.745333478056895 0.0060449436835539 0.9998074779415004 0.1496388690788519 17 Q92896,Q08722,P78310,P35613,Q9Y624,Q9UNN8,P05556,P08195 8
Plasma lipoprotein clearance 0.8917135434640716 2.7111266549205193 0.0067055007417584 0.9999246469374892 0.1577800383764249 13 Q8WTV0,O15118,P61916,P01130 4
Cargo recognition for clathrin mediated endocytosis 0.7012993291626811 2.703199249839743 0.0068675565265496 0.9999401428171294 0.1577800383764249 34 P98164,Q14108,P11717,P01130 4
Plasma lipoprotein assembly remodeling and clearance 0.8327900276837706 2.6601746601830794 0.0078100139274446 0.9999843209939184 0.1669686310852177 17 Q8WTV0,O15118,P61916,P01130,P38571 5
Lysosome vesicle biogenesis 0.851033882143483 2.631265401407755 0.0085067575510395 0.9999941809861446 0.1723039878563917 15 Q9UBR2,P15586 2
Diseases of carbohydrate metabolism 0.9502318645243556 2.6222883688848504 0.0087341493937163 0.9999957898806632 0.1723039878563917 9 P08236,P10253,P15586,P54802 4
Ldl clearance 0.8859862898739962 2.6043666459472883 0.0092044232308554 0.9999978447017686 0.1731658823831608 11 O15118,P61916,P01130 3
Glycosaminoglycan metabolism 0.8324296726724406 2.500169325641066 0.0124133959263599 0.9999999778387808 0.2241636761382845 14 P08236,P16278,P54802,Q96L58,Q7LGA3,P15586,O43252,P07686,O43505,P06865 10
Gpcr ligand binding 0.8889440412629102 2.4962722347491506 0.0125506239652193 0.9999999817845944 0.2241636761382845 10 P07602,P42892 2
Metabolism of carbohydrates 0.5325429152759675 2.4561556093585097 0.0140432333495534 0.9999999978449504 0.2385383719892062 96 P08236,P16278,P54802,O00754,P10253,P15586,O43505,P06865 8
Interferon alpha beta signaling 0.8431530703461214 2.4257793159848933 0.0152755559295427 0.9999999996309646 0.2477449358228144 11 P04439,P01889,P10321 3
Golgi associated vesicle biogenesis 0.6620612427037942 2.394708732608308 0.016633572797216 0.99999999994735 0.2637075417626042 31 P02786,Q9H3P7,O75976,Q99523,P11717 5
Interferon gamma signaling 0.8019043411151202 2.3238604115308275 0.0201329766492777 0.9999999999996558 0.2968973614546462 13 P04439,P01889,P10321,P15260 4
Peptide ligand binding receptors 0.9354433592419896 2.301089783796982 0.0213865566740556 0.9999999999999436 0.3006163190708146 7 P07602,P42892 2
Class a 1 rhodopsin like receptors 0.9354433592419896 2.301089783796982 0.0213865566740556 0.9999999999999436 0.3006163190708146 7 P07602,P42892 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.9521874999999956 2.2927556247202516 0.0218620781123695 0.9999999999999716 0.3024254138877782 6 P78310,Q5KU26,P01889,P04439,P10321 5
Antigen presentation folding assembly and peptide loading of class i mhc 0.7515337001789264 2.277247299911388 0.0227714620238683 0.9999999999999925 0.3119469215114395 17 Q9Y6B6,P55735,P01889,Q15436,P04439,P10321 6
Clathrin mediated endocytosis 0.5760459670110702 2.25341371393213 0.0242330756400606 0.9999999999999992 0.3225742427181652 57 P98164,Q14108,P11717,P01130 4
Antigen processing cross presentation 0.5802294154222826 2.2316194725586325 0.0256401235414345 1.0 0.3381141524949916 52 Q9UIQ6,P28072,P49721,P01889,P04439,P10321 6
Keratan sulfate keratin metabolism 0.9731333958138104 2.214632014103994 0.0267853327627305 1.0 0.3495237084884245 5 O43505,P16278,P15586,P06865 4
Binding and uptake of ligands by scavenger receptors 0.903648971472241 2.1834050906024816 0.0290059914024962 1.0 0.3687158006209209 7 Q5KU26 1
Response to elevated platelet cytosolic ca2 0.6199941416226826 2.175296005369935 0.0296079416887531 1.0 0.3730071939538453 33 P07602,O43852,P05067,Q08380 4
Degradation of the extracellular matrix 0.8839964151332367 2.1098632104271116 0.0348701399231838 1.0 0.4134602305177518 7 P35613,P07858 2
Metabolism of steroids 0.5654538823062374 2.0929650577532195 0.03635227388272 1.0 0.4274421537376493 48 Q15392,O75845,P98164,Q16850,Q9UBM7,Q99538,Q14739,P04062,Q15800 9
Sialic acid metabolism 0.8938540843505548 2.0798064786536483 0.0375432866371374 1.0 0.4343192750679976 6 P16278,P10619 2
Visual phototransduction 0.8379405948661968 2.0797031924551517 0.0375527651015561 1.0 0.4343192750679976 8 P01130 1
Innate immune system 0.5790092189337386 2.0618251637336695 0.0392243844194417 1.0 0.446335535611551 293 Q4KMQ2,Q08722,P07858,P60900,P07602,Q9UBR2,Q99538,P06280,P10253,P15586,P04066,P11717,P05067,P17900,Q8IV08,P53634,P49721,P61916,O15260,O00754,Q92820,P42785,P04439,Q9BTY2,P10321,P08236,P16278,P11279,P10619,P01889,Q92542,P07686,Q13510,Q99519,P28072,P10909 36
Sensory perception 0.6164075930507884 2.046999148514057 0.040658168146465 1.0 0.4553069464655729 27 P23634,P98164,P01130 3
Mucopolysaccharidoses 0.980324797001874 2.038518116921548 0.0414981448117506 1.0 0.4574043064164204 4 P08236,P15586,P54802 3
Regulation of ifng signaling 0.9224510705934552 2.0321137648471694 0.0421421402084583 1.0 0.4574043064164204 5 P15260 1
Endosomal vacuolar pathway 0.9753279200499688 2.020811529993092 0.0432992788066339 1.0 0.4651348380466908 4 Q9UIQ6,P04439,P10321 3
Heparan sulfate heparin hs gag metabolism 0.9187753826929164 2.01874550926628 0.0435136772658846 1.0 0.4651348380466908 5 P08236,Q7LGA3,P16278,P54802 4
Keratan sulfate degradation 0.972829481574016 2.011947692280508 0.0442254512263597 1.0 0.46918880962702 4 P15586,P06865,P16278 3
Transcriptional regulation by e2f6 0.7266983874493622 1.9515730735568824 0.0509889126819869 1.0 0.5102507503140675 12 Q13185,Q96KQ7,O75530,O14727 4
Hemostasis 0.5058737779285927 1.9400927182998344 0.0523684228079666 1.0 0.5177250363277597 124 Q08722,P07602,Q9BUF5,Q08380,Q9BVA1,Q9UNN8,Q02241,P05556,P05067,P08195,P05026,P12814,P42785,P23634,P78310,P35613,Q9Y624,Q07021,Q9H0H5,P84095,P35237,Q92896,Q13362,O43852,Q9H4M9,P61586,P10909 27
Integrin cell surface interactions 0.9515927545284196 1.9363267528349373 0.0528276942102896 1.0 0.5177250363277597 4 Q9Y624,Q08722,P35613 3
Hs gag degradation 0.9800187324383388 1.9332655435233048 0.0532034941655032 1.0 0.5177250363277597 3 P08236,P54802 2
Fatty acyl coa biosynthesis 0.6983369945224729 1.927571405485435 0.053908458419275 1.0 0.5209920193808021 15 Q9UMR5 1
Rac3 gtpase cycle 0.5809265322088379 1.9237856066962185 0.0543814623007767 1.0 0.5219880497033744 33 P02786,Q14126,O15173,Q9UQB8,Q14739,P05556 6
Trafficking and processing of endosomal tlr 0.9697252250524376 1.8959949404450505 0.0579607135629962 1.0 0.534526580636521 3 P07858 1
Retrograde transport at the trans golgi network 0.6797164626217292 1.8789263972406884 0.060254543897243 1.0 0.5492472725916915 16 P11717,Q7Z6M1,Q96MW5,Q147X3 4
Vitamin d calciferol metabolism 0.927755003773661 1.850873125009864 0.0641878079004176 1.0 0.5567944306935904 4 P98164,Q99538 2
Stimuli sensing channels 0.7344870313937968 1.8499106998912695 0.0643264214566583 1.0 0.5567944306935904 10 P51790,Q4KMQ2,Q9C0H2 3
Dap12 interactions 0.871977259839291 1.847069714675818 0.06473703710501 1.0 0.5567944306935904 5 P10321 1
Transport to the golgi and subsequent modification 0.4858668464275122 1.8417944162305055 0.0655052271404224 1.0 0.5567944306935904 76 Q96FJ2,Q9UBR2,Q9BUF5,O95487,P04066,P48444,Q9BVA1,O00743,O15027,P53634,Q13885,P47756,Q9Y6B6,P35606,P84085,Q15436,Q13409,Q13190,Q9HCU5,Q9Y678,Q9NZ32,O95249,P55735,O15084,Q96MW5 25
Diseases of glycosylation 0.6368311917161058 1.8368733383104747 0.0662285960720865 1.0 0.5595721500461922 20 P16278,P10619,P07686,O43505,P06865 5
Cell death signalling via nrage nrif and nade 0.7049062661482939 1.8225132293564328 0.0683771482594055 1.0 0.5708884981894747 11 Q92888,Q92542 2
Cs ds degradation 0.9722222222222257 1.8110058376432403 0.0701399480340529 1.0 0.5787571150646127 2 P06865 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6864944167976533 1.7992168179564068 0.0719843901135812 1.0 0.58888250582708 13 Q9BTY2,P05067 2
Amino acid transport across the plasma membrane 0.9126527658451264 1.7964405230350498 0.072424483944242 1.0 0.58888250582708 4 P30825,Q96QD8 2
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.7654737057502575 1.7887998890913228 0.0736470488170404 1.0 0.58888250582708 8 Q04206,P05067 2
Rnd1 gtpase cycle 0.6761820526261412 1.783971826740145 0.0744282432365515 1.0 0.589990175318956 14 P02786,O75976 2
G alpha i signalling events 0.6121896670209936 1.776465403195013 0.0756562394033015 1.0 0.5963740435645727 22 P07602 1
Formation of fibrin clot clotting cascade 0.9353730877302516 1.770918468253827 0.0765742607542403 1.0 0.5988696108436323 3 P42785,Q9UNN8 2
Traf6 mediated nf kb activation 0.7897290514216408 1.7489475908544936 0.0803000791015837 1.0 0.6051558275296111 7 P05067 1
Chondroitin sulfate dermatan sulfate metabolism 0.89943785134291 1.7486353917204798 0.0803540645237359 1.0 0.6051558275296111 4 Q96L58,P07686,P06865 3
Diseases associated with glycosaminoglycan metabolism 0.89943785134291 1.7486353917204798 0.0803540645237359 1.0 0.6051558275296111 4 Q96L58,P07686,P06865 3
Chl1 interactions 0.9272479603064852 1.7411912332953543 0.0816500634316659 1.0 0.6051558275296111 3 O14786 1
Rho gtpases activate cit 0.731023395001467 1.737767187386978 0.082251844569233 1.0 0.6051558275296111 9 Q15058,O43663 2
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.9247580393381196 1.7320713602132944 0.0832608576980291 1.0 0.6051558275296111 3 Q9Y624,P61586 2
Ecm proteoglycans 0.9509987515605562 1.726605706771746 0.0842385003388306 1.0 0.6051558275296111 2 P05067 1
Hyaluronan uptake and degradation 0.8383650716784109 1.7221920386019522 0.0850347365746078 1.0 0.6051558275296111 5 P08236,P06865 2
Hyaluronan metabolism 0.8383650716784109 1.7221920386019522 0.0850347365746078 1.0 0.6051558275296111 5 P08236,P06865 2
Rac2 gtpase cycle 0.5471548851154527 1.719225234530062 0.0855733676325145 1.0 0.6051558275296111 34 P02786,Q14126,O15173,Q14739,P05556 5
Translocation of slc2a4 glut4 to the plasma membrane 0.5329111118886074 1.704166364039721 0.0883500111944211 1.0 0.6051558275296111 38 Q96A65,Q9Y4I1,Q9UIQ6,Q13885,Q9BUF5,Q96KP1,Q9BVA1,P11233,O60343,Q86X10 10
Non integrin membrane ecm interactions 0.8856698004544175 1.6986669965668382 0.0893819452400561 1.0 0.6051558275296111 4 O14936,P05556 2
Syndecan interactions 0.8856698004544175 1.6986669965668382 0.0893819452400561 1.0 0.6051558275296111 4 O14936,P05556 2
Metabolism of fat soluble vitamins 0.8301936194638283 1.691653667899457 0.0907120273073194 1.0 0.6051558275296111 5 P01130 1
Basigin interactions 0.7893740272338686 1.686321300800813 0.0917339304646833 1.0 0.6051558275296111 6 P35613,P05556,P08195 3
Peptide hormone metabolism 0.6403826181256502 1.6834988506659772 0.0922785616846071 1.0 0.6051558275296111 16 Q96KP1,Q9UBR2 2
Synthesis of pips at the er membrane 0.9109799120661536 1.6815256960216645 0.0926608496086758 1.0 0.6051558275296111 3 P42356 1
Pkmts methylate histone lysines 0.6300068933979894 1.6719972248820127 0.0945248693022149 1.0 0.6051558275296111 17 Q96KQ7,O75530,Q9H7B4,Q04206 4
Intra golgi traffic 0.7151296976290351 1.6703179332428777 0.0948564769118012 1.0 0.6051558275296111 9 O00461,O95249 2
Intrinsic pathway of fibrin clot formation 0.9350811485643028 1.6631495183277714 0.0962825097589967 1.0 0.6051558275296111 2 P42785 1
Intra golgi and retrograde golgi to er traffic 0.4428511037477447 1.6576284758095132 0.0973924784098034 1.0 0.6051558275296111 87 Q9BUF5,P48444,Q9BVA1,Q02241,P11717,Q9H2M9,P20645,Q13885,Q10472,P47756,O15260,Q7Z6M1,P35606,P51151,Q99661,P84085,Q13409,Q9H0H5,O00461,Q147X3,Q9Y678,O95249,Q10471,Q96MW5 24
Interleukin 6 family signaling 0.8210685338602126 1.6574750615880494 0.0974234667592368 1.0 0.6051558275296111 5 P23458 1
Interleukin 6 signaling 0.8210685338602126 1.6574750615880494 0.0974234667592368 1.0 0.6051558275296111 5 P23458 1
Signal transduction by l1 0.709052711745707 1.644427701530087 0.1000878869620645 1.0 0.6113593441708789 9 P19784,P28482,P05556,O14786 4
Potential therapeutics for sars 0.5059082493006338 1.6357829787909552 0.1018850156050372 1.0 0.6162884748498277 43 Q99720,P15260,P05026,P23458,P05556 5
Metabolism of cofactors 0.8118237632491727 1.6227703539539238 0.1046385053911724 1.0 0.6235084425180698 5 P35270 1
Synthesis of pg 0.8647214754719662 1.6223510324384447 0.1047282075668196 1.0 0.6235084425180698 4 Q8IV08 1
Regulated proteolysis of p75ntr 0.9238451935081236 1.6182967713987486 0.1055986561595694 1.0 0.6260491758031617 2 Q92542 1
Nrif signals cell death from the nucleus 0.886244361239637 1.5904802642998372 0.1117265907519482 1.0 0.6435909178708338 3 Q92542 1
Rhoc gtpase cycle 0.5294128660536838 1.5824912175268029 0.1135374756658873 1.0 0.6435909178708338 33 Q92888,P02786,Q14739,Q07021,Q9H0H5 5
Slc mediated transmembrane transport 0.5900221012333003 1.5814413172012085 0.1137771666653284 1.0 0.6435909178708338 20 P30825,Q15043,P35613,Q96QD8 4
P75 ntr receptor mediated signalling 0.5923333983557253 1.5637202602440707 0.1178832776311795 1.0 0.6435909178708338 19 Q13501,Q92888,P61586,Q92542 4
Cargo concentration in the er 0.623325467397569 1.561743238129319 0.1183484884289409 1.0 0.6435909178708338 15 Q9UBR2,P53634 2
The nlrp3 inflammasome 0.7953394391947037 1.560709827279753 0.118592231499941 1.0 0.6435909178708338 5 P05067 1
Purinergic signaling in leishmaniasis infection 0.7953394391947037 1.560709827279753 0.118592231499941 1.0 0.6435909178708338 5 P05067 1
Inflammasomes 0.7953394391947037 1.560709827279753 0.118592231499941 1.0 0.6435909178708338 5 P05067 1
Pexophagy 0.8776147361848259 1.5586406812767364 0.1190814487650442 1.0 0.6437698245497219 3 Q13501,Q13315 2
Amyloid fiber formation 0.7533398326667207 1.5475093327637566 0.1217404757660631 1.0 0.6513283952596919 6 P05067 1
Apoptotic cleavage of cell adhesion proteins 0.7489018131976883 1.5303254126540584 0.1259362010220897 1.0 0.6647546142583686 6 Q16625 1
Activation of ampk downstream of nmdars 0.7462125031316184 1.5199041283541272 0.1285350727446803 1.0 0.6647546142583686 6 Q9BVA1,Q9BUF5 2
Metabolism of vitamins and cofactors 0.4900616412138497 1.517709239168504 0.1290877138956718 1.0 0.6647546142583686 45 P98164,P35270,P01130,Q9NPF0 4
Cdc6 association with the orc origin complex 0.8617600682271647 1.5000656644056312 0.1335973939835082 1.0 0.672965362652646 3 Q9Y619 1
O linked glycosylation of mucins 0.8614485392659167 1.498913884304409 0.1338959739714815 1.0 0.672965362652646 3 O43505 1
O linked glycosylation 0.8614485392659164 1.498913884304408 0.1338959739714817 1.0 0.672965362652646 3 O43505 1
Carboxyterminal post translational modifications of tubulin 0.738023139489043 1.4881329040943003 0.1367158474902561 1.0 0.6746657570107237 6 Q9BVA1,Q9UPW5,Q9BUF5 3
Cholesterol biosynthesis 0.6005575346254644 1.4823200320742849 0.1382551606036917 1.0 0.6750104900062595 16 Q15392,O75845,Q16850,Q14739,Q9UBM7 5
Biotin transport and metabolism 0.6904598928833208 1.4792978980341331 0.1390607144127273 1.0 0.6766023035736495 8 Q13085,P05165,O00763,P50747,P11498,Q96RQ3 6
Signalling to ras 0.8215934884328494 1.4643626161741807 0.1430948968281462 1.0 0.6891020458174552 4 P11233 1
Toll like receptor cascades 0.5033127230982402 1.4556954024005735 0.1454768414227705 1.0 0.6934723758362473 36 P30154,Q15750,Q9BQ95,P07858,P49137,Q99538,Q04206,Q9UQ16,P05067 9
Adaptive immune system 0.5068584444334492 1.452056819741654 0.1464858069898238 1.0 0.6959308877530015 199 P07858,P60900,Q9UIQ6,Q99538,Q9BUF5,Q5KU26,Q9BVA1,Q02241,P05556,P53634,P49721,P04439,Q9UQ16,P10321,Q9Y6B6,Q5XPI4,P78310,P10619,P01889,Q13409,Q15436,P55786,Q9H0H5,P49427,P68036,P28072,Q13362,P55735,P62942,Q05086,Q04206,Q8NEZ5 32
Enos activation 0.8173305884546669 1.4487001506176125 0.1474213383985851 1.0 0.6980251962429653 4 P35270 1
Carnitine metabolism 0.7233529724793784 1.4310933368104692 0.1524034666998148 1.0 0.7073726694521012 6 P23786,O43772 2
P38mapk events 0.8418918045281157 1.426565890791737 0.1537050617733817 1.0 0.7110748923352184 3 P11233 1
Er to golgi anterograde transport 0.4433708565737302 1.4207515179961925 0.1553890096459911 1.0 0.7156625137520366 75 Q96FJ2,Q9UBR2,Q9BUF5,O95487,P48444,Q9BVA1,O00743,O15027,P53634,Q13885,P47756,P53992,Q9Y6B6,P35606,P84085,Q15436,Q13409,Q13190,Q9HCU5,Q9Y678,Q9NZ32,O95249,P55735,O15084,Q96MW5 25
Complement cascade 0.8723470661673068 1.412517432142687 0.1577976615708731 1.0 0.7161687821733256 2 P10909 1
Transport of small molecules 0.472398500131328 1.4113430981335593 0.1581434723114265 1.0 0.7161687821733256 147 Q4KMQ2,P60900,Q15043,P30825,P01130,Q9C0H2,P08195,P05026,P02786,P49721,P61916,P23634,Q15904,Q9Y6B6,O15118,P35613,Q96QD8,P51790,P08183,Q8WTV0,P28072,Q8N4V1,P38571 23
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6046269981051928 1.4106119072646286 0.1583590786945978 1.0 0.7161687821733256 13 Q04206,P05067 2
Ion channel transport 0.511528730267224 1.3980130635225745 0.1621091443255458 1.0 0.7228582945654047 28 P51790,Q4KMQ2,P05026,Q9C0H2,P23634,Q15904 6
Vesicle mediated transport 0.5179762135599902 1.3837707934144257 0.1664286487482773 1.0 0.7279345170448938 256 Q9UIQ6,Q9UBR2,Q9H9H4,Q9BUF5,Q5KU26,P15586,Q14108,Q9H3P7,P01130,O75976,Q99523,Q9BVA1,P11717,P05067,Q02241,P98164,P49815,P53634,P20645,P02786,Q10472,O15260,Q96KP1,Q9UQ16,Q5VZ89,Q7Z6M1,Q86X10,Q9Y6B6,P35606,P22681,Q13409,Q9H0H5,O00461,Q147X3,Q8WTV0,O95295,O95249,P55735,P11233,Q96MW5 40
Rhoa gtpase cycle 0.4719938943891849 1.3828237376638657 0.1667189185906352 1.0 0.7279345170448938 48 Q92888,P02786,O15173,Q14739,Q07021,Q9H0H5,Q15904 7
Metabolism of nitric oxide nos3 activation and regulation 0.7101238691908545 1.3795407213034634 0.1677280999847417 1.0 0.7279345170448938 6 P35270 1
Transport of inorganic cations anions and amino acids oligopeptides 0.624791985395224 1.3647044243175137 0.1723459685217316 1.0 0.7328471474532351 10 P30825,Q96QD8 2
Negative regulation of fgfr4 signaling 0.7027727620882449 1.3508563677949583 0.176741447400933 1.0 0.7328471474532351 6 P22681 1
Negative regulation of fgfr2 signaling 0.7027727620882449 1.3508563677949583 0.176741447400933 1.0 0.7328471474532351 6 P22681 1
Negative regulation of fgfr1 signaling 0.7027727620882449 1.3508563677949583 0.176741447400933 1.0 0.7328471474532351 6 P22681 1
Spry regulation of fgf signaling 0.7027727620882449 1.3508563677949583 0.176741447400933 1.0 0.7328471474532351 6 P22681 1
Negative regulation of fgfr3 signaling 0.7027727620882449 1.3508563677949583 0.176741447400933 1.0 0.7328471474532351 6 P22681 1
Cdc42 gtpase cycle 0.5027303628847192 1.3407211681071205 0.1800109991563077 1.0 0.7328471474532351 28 P02786,Q9UQB8,Q14739 3
Post chaperonin tubulin folding pathway 0.619005128428516 1.338695057350031 0.1806699660004302 1.0 0.7328471474532351 10 Q13885,Q9BVA1,Q99426,Q9BUF5 4
Keratinization 0.685175184063575 1.3355451430863876 0.181697990631009 1.0 0.7328471474532351 7 Q14574 1
Formation of the cornified envelope 0.685175184063575 1.3355451430863876 0.181697990631009 1.0 0.7328471474532351 7 Q14574 1
Transport of connexons to the plasma membrane 0.7853956040692648 1.331242691238049 0.183109168375755 1.0 0.7328471474532351 4 Q9BVA1,Q9BUF5 2
Gap junction assembly 0.7853956040692648 1.331242691238049 0.183109168375755 1.0 0.7328471474532351 4 Q9BVA1,Q9BUF5 2
Defects in biotin btn metabolism 0.6827358354441051 1.325794023443771 0.1849079331954857 1.0 0.7328471474532351 7 Q13085,P05165,P50747,P11498,Q96RQ3 5
Diseases associated with glycosylation precursor biosynthesis 0.6152939246913591 1.322002351525342 0.1861673678760778 1.0 0.7328471474532351 10 P16278,P10619 2
Mapk1 erk2 activation 0.8083883114161714 1.3025949153841172 0.1927130945923676 1.0 0.7328471474532351 3 P23458 1
Selective autophagy 0.4858672951399451 1.301141927194614 0.1932098787048926 1.0 0.7328471474532351 34 Q8N4H5,Q96E29,Q9BUF5,Q00613,Q13315,Q13409,Q9BVA1,Q13501 8
Rhog gtpase cycle 0.4855048172202276 1.298636555595002 0.1940686865092424 1.0 0.7341311438727645 34 P02786,Q14126,O15173,Q14739,Q07960,P84095,P05556 7
Death receptor signalling 0.5036731497719363 1.2930105201356343 0.1960074206110165 1.0 0.7394825413961077 26 Q92888,P61586,Q04206,Q92542,Q13501 5
Erbb2 regulates cell motility 0.8029971901342469 1.2826676003011523 0.1996085556045759 1.0 0.7480753555988231 3 Q9Y316,P61586 2
Ripk1 mediated regulated necrosis 0.5819262480545359 1.2775486056203107 0.2014086318731345 1.0 0.7480753555988231 12 Q9UNE7,Q16543,Q14254,O00560,Q8WUM4 5
Cell cell communication 0.4996314977999774 1.2673888734936387 0.2050162762784264 1.0 0.7480753555988231 26 Q9Y624,O14936,Q08722,P05556 4
Semaphorin interactions 0.5333063186769159 1.2654572370576431 0.2057074684424829 1.0 0.7480753555988231 20 P61586,P05556,O14786 3
G alpha 12 13 signalling events 0.6003800319625646 1.254843726122078 0.2095354957032991 1.0 0.7512754396961211 10 P63218,Q92888,P61586 3
Dna damage reversal 0.6738934397043608 1.2380178092705152 0.2157094573599729 1.0 0.7614268700324368 6 P16455,Q6P6C2,Q9C0B1 3
Interferon signaling 0.440855350847403 1.237448504168864 0.2159206210190167 1.0 0.7614268700324368 65 P04439,P01889,P10321,P15260 4
Gap junction trafficking and regulation 0.5758949867511263 1.2279158658405964 0.2194785529350369 1.0 0.7614268700324368 11 Q9BVA1,Q9BUF5,Q07157 3
Regulation of tp53 activity through methylation 0.671246469953027 1.2276713174726597 0.2195703778081605 1.0 0.7614268700324368 6 Q96KQ7 1
Thrombin signalling through proteinase activated receptors pars 0.7055664044079124 1.220300734221755 0.2223508915803878 1.0 0.7614268700324368 5 P63218 1
Copii mediated vesicle transport 0.4741463309478682 1.2199978473919413 0.2224656909209998 1.0 0.7614268700324368 34 Q9Y6B6,Q9UBR2,P53634 3
Signalling to erks 0.5718467871879321 1.2089911458712757 0.2266662470168137 1.0 0.7667983057129053 11 P28482,P11233,P49137 3
Insulin processing 0.5718020083065065 1.2087817981760305 0.2267466862377944 1.0 0.7667983057129053 11 Q96A65,Q9Y4I1,Q9UPT5,Q96KP1,Q8TAD4 5
Membrane trafficking 0.5005967688317493 1.2026489294036704 0.2291122046948404 1.0 0.769707906724809 249 Q9UIQ6,Q9UBR2,Q9H9H4,Q9BUF5,P15586,Q14108,Q9H3P7,P01130,O75976,Q99523,Q9BVA1,P11717,P05067,Q02241,P98164,P49815,P53634,P20645,P02786,Q10472,O15260,Q96KP1,Q9UQ16,Q5VZ89,Q7Z6M1,Q86X10,Q9Y6B6,P35606,P22681,Q13409,Q9H0H5,O00461,Q147X3,O95295,O95249,P55735,P11233,Q96MW5 38
Interleukin 3 interleukin 5 and gm csf signaling 0.5701004479566415 1.2008266224545143 0.2298184625463988 1.0 0.7702466761353176 11 P23458 1
Transport of bile salts and organic acids metal ions and amine compounds 0.7486326297875054 1.196117664605967 0.2316506451414188 1.0 0.7708940101286369 4 P35613 1
Ptk6 regulates rtks and their effectors akt1 and dok1 0.815855181023741 1.1880284231215752 0.2348222118364782 1.0 0.7759581754128122 2 P22681 1
Runx1 regulates expression of components of tight junctions 0.7766679247778646 1.185558351726855 0.2357967579255544 1.0 0.7773580033480311 3 Q16625 1
P75ntr signals via nf kb 0.7405633549980193 1.1665352212585511 0.2433981168199381 1.0 0.7883083066757247 4 Q13501 1
Nf kb is activated and signals survival 0.7405633549980193 1.1665352212585511 0.2433981168199381 1.0 0.7883083066757247 4 Q13501 1
Metabolism of lipids 0.480698395914654 1.165535526254831 0.2438022884651374 1.0 0.7883083066757247 200 Q15392,O75845,P07602,Q99538,P06280,Q9UMR5,P35790,Q8NBJ7,P04062,P06865,Q8NCC3,Q01469,P50897,P23786,P98164,P17900,Q8IV08,Q06520,Q13614,Q15800,Q9Y6B6,P16278,Q16850,Q14739,P10619,O43772,P07686,Q9UBM7,Q13510,Q99519,P42356,P34913,Q9Y5P4 33
Transferrin endocytosis and recycling 0.5610404450497731 1.1584694993114455 0.2466724916350418 1.0 0.7883083066757247 11 P02786 1
Cytosolic sulfonation of small molecules 0.732842574245391 1.138273556489509 0.2550062723043851 1.0 0.7883083066757247 4 Q06520 1
Crmps in sema3a signaling 0.6828540021904581 1.1341776485175834 0.2567200377430834 1.0 0.7883083066757247 5 O14786 1
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7306423333214349 1.130228552193578 0.2583799316258881 1.0 0.7883083066757247 4 P35270 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.5196955138800812 1.1286681871784572 0.2590378342431905 1.0 0.7883083066757247 18 P05067 1
Pink1 prkn mediated mitophagy 0.5869404756608158 1.1161321216274995 0.2643655843439856 1.0 0.7883083066757247 9 Q96E29,Q8N4H5 2
Ire1alpha activates chaperones 0.4970981340003925 1.1125659222898263 0.2658949030124558 1.0 0.7883083066757247 22 O14773,P43307,P49840,Q13217,O95070 5
Platelet activation signaling and aggregation 0.4328303830317794 1.1065775248988026 0.2684766288814422 1.0 0.7883083066757247 58 P07602,O43852,P05067,Q08380 4
Interleukin 1 signaling 0.4358077588478954 1.10060532240077 0.2710684680905355 1.0 0.7883083066757247 50 P60900,P28072,P49721,Q04206,Q13501,P05067 6
Synthesis of substrates in n glycan biosythesis 0.5254580018097931 1.097234808561014 0.2725387604983975 1.0 0.7883083066757247 16 P16278,P10619 2
Neurotransmitter release cycle 0.6349352594514812 1.0859426283308118 0.2775043755691881 1.0 0.7883083066757247 6 Q96QD8 1
Synthesis of diphthamide eef2 0.7161459130694903 1.077341070472793 0.2813279204026981 1.0 0.7933866428448636 4 Q9BZG8 1
Coenzyme a biosynthesis 0.7871410736579271 1.0754170053530978 0.282188071640622 1.0 0.7933866428448636 2 Q9NVE7 1
Rhoh gtpase cycle 0.4904179123862998 1.0734894484868382 0.2830515703564784 1.0 0.7940074866262249 22 P02786 1
Class i mhc mediated antigen processing presentation 0.4174507191019926 1.0614855485381334 0.2884692970488929 1.0 0.7999777868942671 120 Q8NEZ5,Q9Y6B6,P68036,Q5XPI4,P60900,Q9UIQ6,P28072,P49427,P49721,P55735,P01889,Q05086,Q15436,P55786,P04439,P10321 16
Ephrin signaling 0.663473338389414 1.0609778921564788 0.2886999483546553 1.0 0.7999777868942671 5 O00560 1
Gpvi mediated activation cascade 0.6260134350131792 1.0512430432021975 0.2931469788361012 1.0 0.8031658002674539 6 P61586 1
Mitophagy 0.5317272121448913 1.0390330660366005 0.2987893582708614 1.0 0.8060921983960588 12 Q96E29,Q8N4H5 2
Nephrin family interactions 0.61071637950307 1.0378138965614994 0.2993567058536746 1.0 0.8060921983960588 7 O14936 1
Synthesis of glycosylphosphatidylinositol gpi 0.7740324594257428 1.0245505936763697 0.3055752868205008 1.0 0.8119900747716133 2 Q9Y2B2 1
Defects in vitamin and cofactor metabolism 0.5266561535611323 1.0150135661657187 0.3100993607906164 1.0 0.8191691930579655 12 Q13085,P05165,Q9NPF0,P50747,P11498,Q99707,Q96RQ3 7
Activation of gene expression by srebf srebp 0.5013436439504153 0.9997696608464676 0.3174219913646738 1.0 0.8272014940117565 17 Q16850,O75845 2
Rhob gtpase cycle 0.4727154209491475 0.9968078807450664 0.3188577722674852 1.0 0.8285604358552886 23 Q9H0H5,P02786,Q92888 3
Platelet homeostasis 0.5171069967486253 0.9879811273308589 0.3231618911444078 1.0 0.8351308212541383 13 Q13362,P23634,P63218 3
Aggrephagy 0.4998661919508734 0.965916223260468 0.3340861036959148 1.0 0.84507363181217 16 Q13885,Q9BUF5,Q00613,Q13409,Q9BVA1 5
Cargo trafficking to the periciliary membrane 0.4821397570000921 0.9580549298627576 0.338035060634507 1.0 0.8517276259915882 19 A6NIH7 1
Resolution of d loop structures 0.5636368813343008 0.9470935620385008 0.3435911050107139 1.0 0.856549556837663 8 Q9UQ84,Q13315 2
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5636368813343008 0.9470935620385008 0.3435911050107139 1.0 0.856549556837663 8 Q9UQ84,Q13315 2
Interleukin 1 family signaling 0.4120203320172192 0.9169753832150508 0.3591555398208794 1.0 0.8695334131028252 54 P60900,P28072,P49721,Q04206,Q13501,P05067 6
Signaling by tgfb family members 0.4592620913041851 0.9167461499688258 0.3592756767108058 1.0 0.8695334131028252 23 P28482,Q9Y3F4,P61586,Q9Y624,Q7Z3T8,P22681,P62942,Q9Y4E8,Q93008 9
Rho gtpases activate iqgaps 0.5245599751960416 0.9142044687772272 0.3606094164511622 1.0 0.871266929131147 10 Q9BVA1,Q9BUF5,P30622 3
Regulation of cholesterol biosynthesis by srebp srebf 0.4537186453446208 0.9110933663883248 0.3622461813743363 1.0 0.8737254049900658 24 Q16850,O75845,Q9UBM7 3
Iron uptake and transport 0.4787263867932908 0.9084786404813576 0.363625393742585 1.0 0.8739205947889348 18 P02786 1
Trna modification in the nucleus and cytosol 0.4833774313994819 0.9057840022392832 0.3650501901606926 1.0 0.8739205947889348 17 Q5VV42,Q9NPF4,Q96PZ0,Q2VPK5,Q6YHU6,Q9Y606,P07814 7
Thromboxane signalling through tp receptor 0.6655722556500816 0.8952372770881969 0.3706602616601326 1.0 0.8833682124851631 4 P63218 1
Synthesis of pc 0.5846626391978936 0.8917915571197055 0.3725046679154302 1.0 0.8833682124851631 6 P19784,P35790 2
Signaling by notch4 0.4082900187616757 0.8892410427551503 0.3738735494406435 1.0 0.8842256774070748 44 P28072,P49721,Q92542 3
Rhoj gtpase cycle 0.4624888150556941 0.8878752463109884 0.3746078613301371 1.0 0.8842256774070748 21 O75323,P02786,Q07960 3
Negative feedback regulation of mapk pathway 0.690346427473279 0.8732402832720851 0.3825321221924223 1.0 0.894505152059903 3 P28482 1
Asparagine n linked glycosylation 0.3930311614140191 0.8604292795565414 0.3895524516281048 1.0 0.897416937892647 114 Q9Y6B6,P16278,P35606,P53634,Q9UBR2,Q9BUF5,O95249,P10619,P55735,Q96IJ6,P04066,Q13409,Q15436,Q9BVA1,Q96MW5,Q99519 16
Vitamin b5 pantothenate metabolism 0.6547862357244385 0.8570926869431287 0.3913936624729321 1.0 0.8979779800801745 4 Q13057,Q9NVE7 2
Vxpx cargo targeting to cilium 0.5228657298348574 0.839750651545864 0.4010482077536257 1.0 0.9010939153607692 9 Q96A65,Q96KP1 2
Signaling by egfr in cancer 0.6039608706144007 0.8397405950394656 0.401053847517054 1.0 0.9010939153607692 5 P22681 1
Constitutive signaling by egfrviii 0.6039608706144007 0.8397405950394656 0.401053847517054 1.0 0.9010939153607692 5 P22681 1
Constitutive signaling by ligand responsive egfr cancer variants 0.6039608706144007 0.8397405950394656 0.401053847517054 1.0 0.9010939153607692 5 P22681 1
Diseases of dna repair 0.4915174766949504 0.836012078257053 0.4031481082230144 1.0 0.9024086252569904 11 Q9UQ84,P54132,Q13315 3
Activation of the ap 1 family of transcription factors 0.6442848219862564 0.8202660571831771 0.4120644517758247 1.0 0.9090639000574432 4 P45983,P28482,Q16539 3
Signaling by tgf beta receptor complex 0.4462155998367783 0.8162147838703758 0.4143773027659141 1.0 0.9121472296454052 22 P28482,Q9Y3F4,P61586,Q9Y624,P22681,P62942,Q9Y4E8,Q93008 8
Copi independent golgi to er retrograde traffic 0.4230286610118589 0.813572152919857 0.415890096142737 1.0 0.9140512860707194 27 Q9H2M9,Q13885,Q10472,P47756,Q9BUF5,Q9NZ32,P43034,Q13409,Q9BVA1,Q10471 10
Mtorc1 mediated signalling 0.4861149002213959 0.8113908222318691 0.4171412679951185 1.0 0.9141642503112248 11 Q96B36,P23588,P42345,P62942,P62753 5
Signaling by gpcr 0.3968404646114946 0.7983927696011042 0.4246425978245187 1.0 0.9265870050411408 45 P07602,P42892 2
Adp signalling through p2y purinoceptor 1 0.6591513922668532 0.7647924618238088 0.444395137243964 1.0 0.944695452880016 3 P63218 1
Sars cov infections 0.387104456950203 0.7645113659166202 0.444562566061184 1.0 0.944695452880016 65 Q99720,P15260,P05026,Q10472,P23458,P05556 6
Defective intrinsic pathway for apoptosis 0.4625970468937909 0.7591424884020186 0.4477673249813851 1.0 0.9475212338758434 15 P05067 1
Hsf1 activation 0.4641459416016587 0.7516299699689483 0.452273615048635 1.0 0.9475212338758434 14 Q00613,Q15185,P15927,P25685 4
Hdr through homologous recombination hrr 0.4181224373932575 0.750372491087449 0.4530303940738813 1.0 0.9475212338758434 26 Q9UQ84,P28340,P40937,P54132,Q14191,O60921,Q13315,P15927,Q07864,P56282,Q9NRF9 11
Eph ephrin signaling 0.408791584020782 0.7499027852409659 0.4533132568939739 1.0 0.9475212338758434 32 Q92542,O00560 2
Interleukin 4 and interleukin 13 signaling 0.4630317700204525 0.7315372672925994 0.464451049978869 1.0 0.9475212338758434 13 P23458 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.440457838841998 0.7312262239100746 0.464640984884721 1.0 0.9475212338758434 19 P16278,P10619 2
Sensory processing of sound 0.4402100835636923 0.7298981467252063 0.4654524452214437 1.0 0.9475212338758434 19 Q00013,P20020,P47756,P15311,O14936,P23634 6
Rac1 gtpase cycle 0.3884193368054421 0.723916026953616 0.469117289954712 1.0 0.9475212338758434 42 P02786,Q9UQB8,P05556,Q14739 4
Rhod gtpase cycle 0.4082871949871939 0.7228405985327163 0.4697778215280173 1.0 0.9475212338758434 28 O15173,Q14739,P12814,Q9P2R3,Q9H0H5 5
Recycling of eif2 gdp 0.5294861559180707 0.7204410763075655 0.4712534668904449 1.0 0.9475212338758434 7 P49770 1
Signaling by bmp 0.6906991260924025 0.7143949492427666 0.4749829942713761 1.0 0.9475212338758434 2 Q7Z3T8 1
Signaling by activin 0.6440836715579095 0.7137273351851429 0.4753958000568903 1.0 0.9475212338758434 3 Q13485,P28482 2
Signaling by nodal 0.6440836715579092 0.7137273351851414 0.4753958000568912 1.0 0.9475212338758434 3 Q13485,P28482 2
Displacement of dna glycosylase by apex1 0.6897627965043749 0.7110877677040051 0.4770298495990599 1.0 0.9493499545617398 2 P13051 1
Cd163 mediating an anti inflammatory response 0.6841448189762789 0.6913511085340893 0.4893449209488041 1.0 0.9582676287101144 2 Q16539 1
Activated tak1 mediates p38 mapk activation 0.5619054811628236 0.6892611949583201 0.4906589131361401 1.0 0.9582676287101144 5 Q15750 1
Cell junction organization 0.439890266591265 0.6823542305307346 0.4950149894534927 1.0 0.9634015863708666 17 Q9Y624,P05556 2
Homologous dna pairing and strand exchange 0.4392170040371865 0.6789646886206867 0.4971602360795608 1.0 0.9643390041870252 17 Q9UQ84,P54132,Q13315,O60921 4
Raf independent mapk1 3 activation 0.5179899851567561 0.6771400323590976 0.4983171114101519 1.0 0.9643390041870252 7 P28482,P23458 2
Hdr through single strand annealing ssa 0.4420496236132537 0.6751234826806095 0.4995973154221937 1.0 0.9643390041870252 16 Q9UQ84,P54132,Q13315,O60921 4
Bmal1 clock npas2 activates circadian gene expression 0.6315953793318712 0.6721804652851203 0.5014688155922897 1.0 0.9653103667131252 3 Q86X55,Q15648 2
Sensory processing of sound by outer hair cells of the cochlea 0.443658403091012 0.6677363578470349 0.504301897421298 1.0 0.969441385914784 15 O14936,P23634 2
Amino acids regulate mtorc1 0.4454616017857858 0.6636718188983488 0.5069003799042435 1.0 0.971788635930554 14 P36543,P21283,P55735 3
Egfr downregulation 0.51307343898936 0.6588033241573331 0.5100220724264533 1.0 0.9751094640088752 7 P22681,Q99961 2
Kinesins 0.4240143924452657 0.6566641603575009 0.5113968840301684 1.0 0.9751094640088752 20 Q9BUF5,Q99661,Q9H0H5,Q9BVA1,Q02241 5
Pre notch processing in the endoplasmic reticulum 0.6713483146067496 0.647112441512612 0.5175591736804537 1.0 0.9789767936032958 2 Q04721 1
Uch proteinases 0.3775805095960656 0.6428901235504477 0.5202953984355312 1.0 0.9790989787361106 48 Q8NB78,P49721,P28072 3
Glucagon signaling in metabolic regulation 0.5466785225344382 0.6366252334006447 0.5243689848403443 1.0 0.9790989787361106 5 P63218 1
Vasopressin regulates renal water homeostasis via aquaporins 0.5466785225344382 0.6366252334006447 0.5243689848403443 1.0 0.9790989787361106 5 P63218 1
Nrage signals death through jnk 0.4869174155697469 0.635610950615268 0.5250300302491713 1.0 0.9790989787361106 8 Q92888 1
Signaling by fgfr3 0.5058367182757728 0.6320300000399756 0.5273672741597761 1.0 0.9790989787361106 7 P22681 1
Signaling by fgfr4 0.5058367182757728 0.6320300000399756 0.5273672741597761 1.0 0.9790989787361106 7 P22681 1
Signaling by fgfr1 0.5058367182757728 0.6320300000399756 0.5273672741597761 1.0 0.9790989787361106 7 P22681 1
Mitochondrial protein import 0.3856438611870943 0.6026527501101225 0.5467397205785194 1.0 0.992864011474623 33 Q99595,O60830,Q8N4H5 3
Prolactin receptor signaling 0.6084920387137004 0.5974590972928887 0.5502009077394003 1.0 0.992864011474623 3 Q13616,Q06124 2
Regulation of bach1 activity 0.6084920387137003 0.597459097292888 0.5502009077394008 1.0 0.992864011474623 3 Q13616,Q13309 2
Regulation of runx3 expression and activity 0.380534173533953 0.5921426484961547 0.5537550700842773 1.0 0.992864011474623 36 P28072,P49721 2
Antigen processing ubiquitination proteasome degradation 0.3473527529706488 0.5817444007232123 0.5607388594063538 1.0 0.9977296074732154 94 Q8NEZ5,P68036,Q5XPI4,P60900,Q9UIQ6,P28072,P49721,Q05086,P55786,P49427 10
Scf skp2 mediated degradation of p27 p21 0.3744248686085574 0.5806981993784339 0.5614438755022912 1.0 0.9977296074732154 39 P28072,P49721 2
Autophagy 0.3685691893519164 0.5676140841337289 0.5702970415971804 1.0 1.0 52 P49815,Q8N4H5,Q96E29,P50542,Q9H9H4,Q9BUF5,Q00613,Q13315,Q13409,Q9BVA1,Q13501 11
Sumo is transferred from e1 to e2 ube2i ubc9 0.647315855181023 0.5670296175647004 0.5706940594225716 1.0 1.0 2 Q9UBT2 1
Processing and activation of sumo 0.647315855181023 0.5670296175647004 0.5706940594225716 1.0 1.0 2 Q9UBT2 1
Sumo is conjugated to e1 uba2 sae1 0.647315855181023 0.5670296175647004 0.5706940594225716 1.0 1.0 2 Q9UBT2 1
Assembly and cell surface presentation of nmda receptors 0.4560267702465164 0.564758349507336 0.5722381402383336 1.0 1.0 9 O14936,Q9BVA1,Q9BUF5,Q14168 4
Fcgamma receptor fcgr dependent phagocytosis 0.3771485140875862 0.5607598891145419 0.5749612340487167 1.0 1.0 35 Q8IV08,Q9UQB8 2
Tgf beta receptor signaling activates smads 0.4265730833468615 0.5494779656685671 0.5826774818999474 1.0 1.0 11 Q9Y4E8,Q9Y3F4,P22681,P62942 4
Negative regulation of notch4 signaling 0.3673216528689076 0.5423128426422911 0.5876030099203333 1.0 1.0 40 P28072,P49721 2
Fanconi anemia pathway 0.4888329407420717 0.5422439847306444 0.5876504383029162 1.0 1.0 6 P27694,P15927,Q9BXW9 3
Formation of tubulin folding intermediates by cct tric 0.4209999062075871 0.5331716638505611 0.593914754739099 1.0 1.0 12 Q9BVA1,Q9BUF5 2
Tp53 regulates transcription of caspase activators and caspases 0.5572781989754678 0.5325463384727289 0.5943476567488339 1.0 1.0 4 O14727 1
Tp53 regulates transcription of cell death genes 0.4470955112597345 0.52995224813958 0.596145039265984 1.0 1.0 9 O14727,Q13315 2
Downstream signaling events of b cell receptor bcr 0.3606939181572215 0.5294637231133458 0.5964838033900992 1.0 1.0 44 P28072,P62942,P49721,P60900 4
Diseases of immune system 0.5529154110928949 0.5192186210823148 0.6036082951004054 1.0 1.0 4 Q04206 1
Suppression of apoptosis 0.5522961859375923 0.5173376532453634 0.6049204737893206 1.0 1.0 4 P49840 1
Neurexins and neuroligins 0.4550504932274721 0.5142640311558009 0.6070674056983418 1.0 1.0 8 Q96HC4,O14936,Q14168 3
Glycerophospholipid biosynthesis 0.3729880677616359 0.5141855999312339 0.6071222345851888 1.0 1.0 32 Q8IV08,Q8WUK0,P35790,P40939,Q8NCC3 5
Cellular response to hypoxia 0.3633388855988542 0.5033635191872144 0.6147087153361097 1.0 1.0 39 P28072,P49721 2
Cross presentation of soluble exogenous antigens endosomes 0.3668426767791077 0.4997512079843709 0.6172502704311518 1.0 1.0 36 P28072,P49721 2
Degradation of axin 0.3668426767791077 0.4997512079843709 0.6172502704311518 1.0 1.0 36 P28072,P49721 2
Metabolism of polyamines 0.3650930033094837 0.496293005211163 0.6196877006315074 1.0 1.0 37 P28072,P49721 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4120000647451405 0.4952508120810435 0.6204230871755729 1.0 1.0 12 Q9BZG8,Q8NBJ7 2
Intraflagellar transport 0.4083737348433122 0.4873659900331547 0.6259989906447188 1.0 1.0 13 Q96EX3,Q13885,Q9BUF5,Q92973,Q9BVA1 5
Maturation of sars cov 2 nucleoprotein 0.4712946818569712 0.4836677022634197 0.6286217182723188 1.0 1.0 6 P78362,P49840 2
Platelet sensitization by ldl 0.4609136083057062 0.4729169130652119 0.6362724579504129 1.0 1.0 7 Q13362 1
Signaling by the b cell receptor bcr 0.3540346590845096 0.4684048505705524 0.6394950999471607 1.0 1.0 47 P28072,P62942,P49721,P60900 4
Tnfr2 non canonical nf kb pathway 0.3543204872489947 0.4626174736913994 0.643638581456706 1.0 1.0 41 P28072,P49721 2
Mtor signalling 0.3957346362777312 0.4563681578804374 0.6481252593030689 1.0 1.0 16 P49815,P23588,P62753,P42345,P31749,P62942,Q96B36 7
Regulation of ras by gaps 0.3564663569389006 0.456217940154065 0.6482332659449512 1.0 1.0 39 P28072,P49721 2
Auf1 hnrnp d0 binds and destabilizes mrna 0.3531256575482688 0.4542734851266901 0.6496319977034297 1.0 1.0 41 P28072,P49721 2
Phase ii conjugation of compounds 0.3651246912075125 0.4540727474584841 0.6497764675712436 1.0 1.0 29 Q06520,Q9HBK9,O43252,P48507,P48506 5
Cell extracellular matrix interactions 0.4379975165951908 0.4523913651775748 0.6509870664117483 1.0 1.0 8 P05556 1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.608614232209737 0.4478487522007581 0.6542623561018921 1.0 1.0 2 O00767 1
Fbxw7 mutants and notch1 in cancer 0.6083021223470748 0.4469432838538762 0.6549160108747016 1.0 1.0 2 Q13616 1
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.3957652366355196 0.4420307437999427 0.6584669589041339 1.0 1.0 14 Q96KQ7 1
G beta gamma signalling through pi3kgamma 0.4859087783620984 0.440758058491457 0.65938816008303 1.0 1.0 5 P63218,P61586 2
G1 s dna damage checkpoints 0.3527275109954876 0.4406760036846226 0.659447571136619 1.0 1.0 40 P28072,P49721,P60900 3
Erks are inactivated 0.4509134637645609 0.4395210575690392 0.6602840273825206 1.0 1.0 7 P30154 1
Suppression of phagosomal maturation 0.4504532666458422 0.4380049503612063 0.6613826948864849 1.0 1.0 7 P52294,Q14974,Q9UI12,Q9H267,P51149,P20339 6
Frs mediated fgfr1 signaling 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr3 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr2 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Frs mediated fgfr4 signaling 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Frs mediated fgfr2 signaling 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Frs mediated fgfr3 signaling 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Activated ntrk2 signals through frs2 and frs3 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr1 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr4 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Tie2 signaling 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Stat5 activation 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.604868913857677 0.4370465509332423 0.6620775885666379 1.0 1.0 2 Q06124 1
Trafficking of glur2 containing ampa receptors 0.4501475992163778 0.4369989751504877 0.6621120912833316 1.0 1.0 7 O95782,P46459,P05771 3
Stabilization of p53 0.353302757034739 0.4347514878851546 0.6637428211561769 1.0 1.0 39 P28072,P49721,P60900 3
Mrna decay by 5 to 3 exoribonuclease 0.4207084995539155 0.4309900139784326 0.6664756314786175 1.0 1.0 9 Q9NPI6 1
Degradation of dvl 0.3536130296745691 0.4279140028274046 0.6687137319200283 1.0 1.0 38 P28072,P49721 2
Rnd2 gtpase cycle 0.3840959146727469 0.4258438665081182 0.6702216201499318 1.0 1.0 18 P02786 1
Apoptotic cleavage of cellular proteins 0.3796561297548241 0.4192139921684806 0.6750597470684483 1.0 1.0 19 Q16625 1
Asymmetric localization of pcp proteins 0.35148414290707 0.4137650246961559 0.679046200636549 1.0 1.0 38 P28072,P49721 2
Regulation of tp53 expression and degradation 0.3914476124225974 0.4077699926834492 0.6834425458294813 1.0 1.0 11 Q13362,P30154,P42345,Q13315 4
Translation of sars cov 1 structural proteins 0.4411291129331159 0.4077010227002302 0.683493186545099 1.0 1.0 7 Q10472 1
Ion homeostasis 0.3903769657758731 0.4036607043999902 0.6864622396249789 1.0 1.0 11 P05026 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.4445087835496647 0.3990423681507297 0.6898619862098883 1.0 1.0 6 P63218 1
Dectin 1 mediated noncanonical nf kb signaling 0.3430342508115922 0.3955038428189287 0.692471086160173 1.0 1.0 42 P28072,P49721,P60900 3
Cyclin a cdk2 associated events at s phase entry 0.3411716583413651 0.394246280341742 0.6933992200674339 1.0 1.0 43 P28072,P49721 2
Cdt1 association with the cdc6 orc origin complex 0.3471117486028273 0.3932194868002492 0.6941573781965338 1.0 1.0 39 P28072,P49721 2
Erythropoietin activates ras 0.5351233218857251 0.3843851005650149 0.7006930419366735 1.0 1.0 3 P62993,P46109 2
Fceri mediated nf kb activation 0.3415928522994111 0.3823843377966656 0.7021763059527051 1.0 1.0 46 Q15750,P60900,P28072,P49721,Q04206 5
Degradation of gli1 by the proteasome 0.3433650804159812 0.3772242975848833 0.7060069249588974 1.0 1.0 40 P28072,P49721 2
Stat3 nuclear events downstream of alk signaling 0.5028536982676242 0.3768293608187104 0.706300419691791 1.0 1.0 4 Q96ST3 1
Darpp 32 events 0.4156547117462917 0.3753689443390509 0.7073860979775732 1.0 1.0 8 P30154 1
Nuclear receptor transcription pathway 0.5009666962719446 0.3718869756941341 0.7099770026856396 1.0 1.0 4 P04150,O75376 2
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.4329301093645205 0.364541379214269 0.715453780177127 1.0 1.0 6 P30154,P49643,P49642 3
Regulated necrosis 0.3759982601276594 0.3644041045215848 0.7155562709149064 1.0 1.0 15 Q9UNE7,Q16543,Q14254,O00560,P09429,Q8WUM4 6
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5257571027161964 0.3604746593375512 0.7184922035824592 1.0 1.0 3 Q16539,P54646 2
Attenuation phase 0.378022250664583 0.3599317927438641 0.7188981410230748 1.0 1.0 12 Q00613,Q15185,P25685 3
Dscam interactions 0.4951047013634194 0.3567514373177992 0.7212778944572866 1.0 1.0 4 P45983,Q16539 2
Hedgehog on state 0.3385657636786962 0.3545624255471203 0.7229174295838412 1.0 1.0 41 P28072,P49721 2
Copi dependent golgi to er retrograde traffic 0.3376091183776485 0.3499535877188542 0.7263735294526144 1.0 1.0 47 P35606,Q9Y678,Q9BUF5,O15260,Q99661,P84085,P48444,Q9H0H5,Q9BVA1,Q02241 10
Hedgehog ligand biogenesis 0.3400069841500397 0.3464166885984299 0.7290295849664363 1.0 1.0 39 P28072,P49721 2
Regulation of runx2 expression and activity 0.3348383848268499 0.3447891886008058 0.7302528615076307 1.0 1.0 44 P28072,P49721 2
Transcriptional regulation by runx3 0.3350115861546525 0.3406446802040308 0.7333710890568645 1.0 1.0 42 P28072,P49721 2
Growth hormone receptor signaling 0.4228125000000106 0.335538149281691 0.7372191719566203 1.0 1.0 6 P40763,P28482,P18031,P07948,P27361 5
Signaling by pdgfr in disease 0.422812500000008 0.3355381492816836 0.7372191719566259 1.0 1.0 6 P40763,Q8TAF3,O43815,P62993,Q6UN15 5
Clec7a dectin 1 signaling 0.3354419579939535 0.3307263799085033 0.7408511743015742 1.0 1.0 48 Q15750,P60900,P28072,P49721,Q04206 5
Wnt ligand biogenesis and trafficking 0.4455974283775519 0.3277244809391548 0.7431199916384505 1.0 1.0 5 Q9UBQ0,O60493 2
Scavenging by class f receptors 0.4834478450968112 0.3276642499575946 0.7431655367689025 1.0 1.0 4 Q92598,Q9Y4L1,P27797 3
Prolonged erk activation events 0.4145077506547011 0.3259397137536979 0.7444699677501951 1.0 1.0 7 Q02750,P28482,Q9ULH0,P46109 4
Map2k and mapk activation 0.3683881064162859 0.322557479803304 0.7470303999385302 1.0 1.0 11 P28482,Q9Y2Q5,P30086,P31946,Q9Y490,Q02750,P18206,P27361,P10398,P46940 10
Metabolic disorders of biological oxidation enzymes 0.4126813310146234 0.3076352720899896 0.7583598777092644 1.0 1.0 6 P48507 1
Dna replication initiation 0.3940334162030073 0.3059966466972897 0.7596071989504369 1.0 1.0 8 P09884,Q07864,Q9NRF9,P49643,P49642 5
Toll like receptor tlr1 tlr2 cascade 0.3456069188193515 0.3052212789345321 0.7601976269252382 1.0 1.0 25 P30154,Q15750,Q9BQ95,P49137,Q04206,P05067 6
Signaling by vegf 0.3390215685855594 0.3047164281740199 0.7605821364262813 1.0 1.0 32 P61586,P49137,Q9UQB8,O14786 4
Attachment of gpi anchor to upar 0.4364380059203152 0.3043909672192195 0.760830048629916 1.0 1.0 5 Q92643,Q969N2 2
Regulation of pten stability and activity 0.3293946298878009 0.3030528664971336 0.7618495731024653 1.0 1.0 42 P28072,P49721 2
E3 ubiquitin ligases ubiquitinate target proteins 0.3554391445743365 0.2903740671449656 0.7715300808635543 1.0 1.0 17 P68036,P04439 2
Alk mutants bind tkis 0.4051876424626127 0.2877677769067889 0.773524504759245 1.0 1.0 6 O43815,Q9HC35,Q9NR09,P10644 4
Grb2 sos provides linkage to mapk signaling for integrins 0.5455680399500613 0.2862483745441038 0.7746878955264522 1.0 1.0 2 P62993 1
G protein beta gamma signalling 0.4004689478639259 0.2859990002477711 0.7748788872755454 1.0 1.0 7 P63218,P61586 2
Rna polymerase iii transcription initiation from type 1 promoter 0.3572714440814487 0.2847829716484724 0.775810418923514 1.0 1.0 12 Q9UKN8,Q9Y5Q8 2
Diseases of programmed cell death 0.3360781726599404 0.2837851346075118 0.7765750472554478 1.0 1.0 27 Q07021,P05067 2
Smad2 smad3 smad4 heterotrimer regulates transcription 0.4279700601148855 0.2836691379706665 0.7766639478918282 1.0 1.0 5 Q13485,P28482 2
Nef mediated cd8 down regulation 0.3987500000000105 0.2712451850743505 0.7862024624561297 1.0 1.0 6 Q9UI12,Q96CW1,P63010,P53680,O95782 5
Nef mediated cd4 down regulation 0.3987500000000105 0.2712451850743505 0.7862024624561297 1.0 1.0 6 Q9UI12,Q96CW1,P63010,P53680,O95782 5
Signaling by kit in disease 0.4226804123711303 0.271152605020817 0.7862736635328322 1.0 1.0 5 P40763,P07947,P07948,P62993 4
Activation of smo 0.5383895131086132 0.2707990749025941 0.7865455714234146 1.0 1.0 2 Q9Y496 1
L1cam interactions 0.3272651234508794 0.2651454933038912 0.7908973824842112 1.0 1.0 39 O95372,Q9BUF5,O00560,Q9BVA1,P05556,O14786 6
Role of lat2 ntal lab on calcium mobilization 0.5349563046192248 0.26363764325114 0.7920591492712705 1.0 1.0 2 P62993 1
Fcgr activation 0.5349563046192249 0.2636376432511395 0.792059149271271 1.0 1.0 2 P07947 1
Free fatty acids regulate insulin secretion 0.5330836454431983 0.2597938415332446 0.7950228016414529 1.0 1.0 2 O95573 1
C type lectin receptors clrs 0.3267759110402562 0.2571881801029418 0.7970335081015176 1.0 1.0 52 Q15750,P60900,P28072,P49721,Q04206 5
Prevention of phagosomal lysosomal fusion 0.4500312304809458 0.2522712191392037 0.8008314326451182 1.0 1.0 4 P20339,Q9H267,P51149 3
The role of gtse1 in g2 m progression after g2 checkpoint 0.3239099032544401 0.2511970153939543 0.8016617919739739 1.0 1.0 48 P20618,P60900,Q13885,P28072,P49721,Q9BUF5,O75832,Q15691,P25788,Q9BVA1 10
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3226506311686861 0.2506081076929706 0.8021171126953941 1.0 1.0 41 P28072,P49721 2
Oas antiviral response 0.4758039338120454 0.2483665197252357 0.8038508355232354 1.0 1.0 3 Q6L8Q7,P21333 2
E2f mediated regulation of dna replication 0.3454824810330592 0.2456377148523933 0.8059626912891882 1.0 1.0 11 P30154,Q9Y619,O43913,P49643,P49642 5
Constitutive signaling by akt1 e17k in cancer 0.3731814526424012 0.2446923088105452 0.8066946837247404 1.0 1.0 8 P49840,P49815,P42345,P31749 4
Golgi to er retrograde transport 0.3219391243996042 0.2430993043583405 0.8079284700958418 1.0 1.0 70 Q9H2M9,P35606,Q13885,Q10472,Q9Y678,P47756,Q9BUF5,Q99661,O15260,P84085,P48444,Q13409,Q9H0H5,Q9BVA1,Q10471,Q02241 16
Rna polymerase iii transcription 0.3409677608360579 0.2305926943780526 0.8176312437165909 1.0 1.0 13 Q9UKN8,Q9Y5Q8 2
Sphingolipid de novo biosynthesis 0.3392502055824824 0.2251192777395724 0.8218864843951765 1.0 1.0 12 Q9Y5P4,Q9P0L0 2
Abc family proteins mediated transport 0.3197212676922197 0.2231857693774799 0.8233909270181301 1.0 1.0 48 P28072,P08183,P49721 3
Beta catenin phosphorylation cascade 0.3643194762696308 0.2204794694491839 0.8254977600001565 1.0 1.0 8 Q13362 1
Signaling by ctnnb1 phospho site mutants 0.3643194762696308 0.2204794694491839 0.8254977600001565 1.0 1.0 8 Q13362 1
Retrograde neurotrophin signalling 0.3543947450735053 0.2170578976309666 0.828163224545607 1.0 1.0 9 Q00610,P50570,O94973,Q96CW1,P63010,P53680,O95782,Q9UQ16 8
Leishmania infection 0.3177452277263333 0.2146938253019533 0.8300060370261648 1.0 1.0 47 Q9Y4I1,Q9UQB8,Q04206,P63218,P05067 5
Cardiac conduction 0.3355896498674159 0.2136987219737482 0.8307820080393771 1.0 1.0 12 P05026 1
Biological oxidations 0.3158318945499212 0.2124176261517648 0.8317812358495797 1.0 1.0 45 Q96DG6,Q16850,Q06520,Q5VT66,Q9HBK9,O43252,P48507,P48506 8
Chrebp activates metabolic gene expression 0.3940547464854931 0.2094050976283262 0.8341320136490289 1.0 1.0 5 O00763 1
Orc1 removal from chromatin 0.3174860629118647 0.2084475444696135 0.8348795364028951 1.0 1.0 48 P28072,P49721 2
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3218263327957193 0.2062418815872744 0.8366019742305149 1.0 1.0 31 Q15185,Q96FJ2,P31689,Q13885,P04150,Q9BUF5,P47756,Q9NZ32,Q13409,P25685,Q9BVA1 11
Regulation of hmox1 expression and activity 0.3145029232890569 0.2038916094396002 0.838438202052944 1.0 1.0 45 P28072,P49721 2
Energy dependent regulation of mtor by lkb1 ampk 0.3574292363567186 0.2024598847823844 0.8395572162817957 1.0 1.0 8 P49815 1
Platelet aggregation plug formation 0.3678125000000065 0.1993248294212501 0.8420086577790686 1.0 1.0 6 P46108,P31749,Q9Y490,P18031,P62993 5
Integrin signaling 0.3678125000000065 0.1993248294212501 0.8420086577790686 1.0 1.0 6 P46108,P31749,Q9Y490,P18031,P62993 5
Galactose catabolism 0.4978152309612971 0.195737589564288 0.8448155612482053 1.0 1.0 2 P51570 1
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.3542839274546598 0.19447496716435 0.8458039948408462 1.0 1.0 8 Q00610,O94973,P09497,Q96CW1,P63010,P53680,O95782 7
Synthesis of udp n acetyl glucosamine 0.4194253591505272 0.1944434469785926 0.8458286732716174 1.0 1.0 4 Q16222,Q9UJ70,O95394 3
Meiotic recombination 0.3366538717849817 0.1923635211753366 0.8474574646295674 1.0 1.0 10 P54132,Q13315 2
Negative regulation of mapk pathway 0.3285583630277756 0.1912761626556647 0.8483092357320476 1.0 1.0 13 Q13362,P30154,P28482 3
Signaling by egfr 0.3271107635397328 0.190380446085002 0.849011019216549 1.0 1.0 11 Q14155,Q99961,P22681 3
Defective cftr causes cystic fibrosis 0.311835119886061 0.1837056037854326 0.8542444125457145 1.0 1.0 41 P28072,P49721 2
Abc transporter disorders 0.311835119886061 0.1837056037854326 0.8542444125457145 1.0 1.0 41 P28072,P49721 2
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3252974326862807 0.1829296234441614 0.8548532389251515 1.0 1.0 12 P49368,P17987,P19784,P50990,P50991,P78371,P40227,P67870,Q99832,P63218,Q9UBI6 11
Signaling by ptk6 0.3251796806979878 0.1804964017048902 0.8567628790293873 1.0 1.0 14 P22681 1
Rho gtpases activate paks 0.3403190491085435 0.1798231167157565 0.8572914349239575 1.0 1.0 9 P35580,Q16512,Q14247,P21333,Q13177,P35579,P63000,P60660 8
E2f enabled inhibition of pre replication complex formation 0.3755942574946612 0.1751814082967754 0.860937092461332 1.0 1.0 5 Q9Y619 1
Pcp ce pathway 0.3132584502898784 0.17264794137592 0.8629281659206627 1.0 1.0 50 P28072,P49721,P60900 3
Vldlr internalisation and degradation 0.3541731791184868 0.1724545569374574 0.8630801843555838 1.0 1.0 7 Q00610,O94973,Q96CW1,P63010,P53680,O95782 6
Recognition of dna damage by pcna containing replication complex 0.3228690677617598 0.1722547965594737 0.8632372202045429 1.0 1.0 19 P28340,P40937,P15927,Q07864,P56282,Q9NZJ0,Q9NRF9 7
Gap junction degradation 0.3540625000000077 0.1715614644321721 0.8637823051086102 1.0 1.0 6 Q00610,P50570,P09497,Q96CW1,Q9UM54 5
Inlb mediated entry of listeria monocytogenes into host cell 0.3531334158810952 0.1697821137493888 0.8651814938556737 1.0 1.0 6 P22681 1
Toll like receptor 9 tlr9 cascade 0.3145061967673225 0.1692722421235184 0.8655825084754185 1.0 1.0 28 P30154,Q15750,Q9BQ95,P49137,Q04206,P05067 6
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4224164845457297 0.1600600839387203 0.8728337441196647 1.0 1.0 3 P40763,P62993 2
Rho gtpases activate ktn1 0.3384166521179699 0.1565677784975366 0.875585498334186 1.0 1.0 8 P61586 1
Mapk6 mapk4 signaling 0.3095265495358601 0.152795738784984 0.8785593582335145 1.0 1.0 49 P28072,P49721 2
Ctla4 inhibitory signaling 0.3210747928198144 0.1520543647619627 0.8791440572301499 1.0 1.0 10 Q13362,P30154 2
Cyclin a b1 b2 associated events during g2 m transition 0.3124397292325883 0.1507889441690806 0.88014220781728 1.0 1.0 11 P30154,Q99640,O95067 3
Synthesis of pips at the golgi membrane 0.3180737214927764 0.1448000915023536 0.8848687099785502 1.0 1.0 10 Q08AM6,P42356 2
Degradation of beta catenin by the destruction complex 0.3085641572857743 0.14257220117307 0.8866280534071223 1.0 1.0 50 P28072,P49721,P60900 3
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.3369024124185706 0.1406951024528596 0.8881108142860803 1.0 1.0 6 P04150,Q96ST3,Q92769 3
Flt3 signaling 0.3361163816197502 0.1393827845336506 0.889147675516299 1.0 1.0 6 P22681 1
Tcr signaling 0.3066501412278608 0.1305305303609829 0.896146701032519 1.0 1.0 50 P28072,P49721,P60900 3
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.3115400026704264 0.1295903426144135 0.8968905442908046 1.0 1.0 10 P68036,P49427,Q93008 3
Nef and signal transduction 0.4435081148564282 0.1274940563591276 0.8985493771331761 1.0 1.0 2 Q13177 1
Termination of translesion dna synthesis 0.3100524296320051 0.1252564622438168 0.9003205187536261 1.0 1.0 17 P28340,P40937,P27694,P15927,Q07864,P56282,Q9NRF9 7
Signaling by leptin 0.4410112359550548 0.1251830331384742 0.9003786491698611 1.0 1.0 2 Q06124 1
Transcriptional regulation of pluripotent stem cells 0.4410112359550548 0.1251830331384742 0.9003786491698611 1.0 1.0 2 Q13485 1
Arms mediated activation 0.3911957539806337 0.1237885358216831 0.9014827090838092 1.0 1.0 3 P31946,Q9ULH0 2
Cd28 dependent vav1 pathway 0.3398937831927563 0.1217895398285306 0.903065698287236 1.0 1.0 5 P63000,Q13177,Q16512,P62993 4
Bbsome mediated cargo targeting to cilium 0.3246875000000123 0.1213067432561356 0.903448079118395 1.0 1.0 6 P49368,P17987,P50990,P50991,P78371 5
Fc epsilon receptor fceri signaling 0.3071238150328854 0.1152466844429509 0.9082495963277096 1.0 1.0 56 P20618,P28482,Q15750,P60900,P28072,P49721,Q04206,P49427 8
Protein ubiquitination 0.3040763086417559 0.1126163730030098 0.9103347038505184 1.0 1.0 26 P68036,P22314,P49427,P50542,Q6PD62,P04439,Q93008 7
Creb1 phosphorylation through the activation of adenylate cyclase 0.3768342179206911 0.1106651027916502 0.911881919893126 1.0 1.0 3 P13861,P10644 2
Pka mediated phosphorylation of creb 0.3768342179206911 0.1106651027916502 0.911881919893126 1.0 1.0 3 P13861,P10644 2
Pka activation in glucagon signalling 0.3768342179206911 0.1106651027916502 0.911881919893126 1.0 1.0 3 P13861,P10644 2
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.3721511083359291 0.10683923427708 0.9149165211422564 1.0 1.0 3 P05771,P17931 2
Negative regulation of met activity 0.3142891991114722 0.1068143341169683 0.9149362755550714 1.0 1.0 8 P22681 1
Listeria monocytogenes entry into host cells 0.3142259117270387 0.1066966269115041 0.9150296586667525 1.0 1.0 8 P22681 1
Transcriptional regulation by ventx 0.3007220480620018 0.1053473820867165 0.9161001666500106 1.0 1.0 15 Q96KQ7 1
Gab1 signalosome 0.3674679987511651 0.1032274575138928 0.917782448369608 1.0 1.0 3 P62993,Q06124 2
Glutathione synthesis and recycling 0.3111298463265379 0.1022837710699343 0.9185314365528294 1.0 1.0 6 P48507 1
Glycogen synthesis 0.3227116526085664 0.1019806415544959 0.9187720407643564 1.0 1.0 5 P46976,Q96G03,P13807,Q16851 4
Disinhibition of snare formation 0.3615360599437969 0.0989509146165279 0.921177243213473 1.0 1.0 3 O00186,P05771 2
Akt phosphorylates targets in the cytosol 0.3123104143248344 0.0966112411209062 0.9230351291344971 1.0 1.0 7 P49840,P49815,P31749 3
Trna modification in the mitochondrion 0.3042168220079939 0.09357734415447 0.9254449073723005 1.0 1.0 6 Q9Y606 1
Gp1b ix v activation signalling 0.3945068664169773 0.0933313124257909 0.9256403569233256 1.0 1.0 2 P21333 1
Pentose phosphate pathway 0.306441525953722 0.0927325671945255 0.9261160235980956 1.0 1.0 8 Q96G03,P37837,O95336,P11908,P60891,P52209,P29401 7
Aquaporin mediated transport 0.3029560243223277 0.0920605387393275 0.9266499407874768 1.0 1.0 6 P63218 1
Abc transporters in lipid homeostasis 0.390449438202246 0.0914372660268167 0.9271451517529036 1.0 1.0 2 P28288 1
Polo like kinase mediated events 0.3023614954586954 0.0913528306543592 0.9272122406483968 1.0 1.0 6 Q99640 1
Inla mediated entry of listeria monocytogenes into host cells 0.3898252184769023 0.0911566977891833 0.9273680818020842 1.0 1.0 2 O60716 1
Pi3k akt signaling in cancer 0.2918812211993257 0.0895058061130079 0.9286799394950728 1.0 1.0 14 P49815,P49840,P42345,P31749,P84095,Q96B36 6
Pyrimidine salvage 0.3842072409488125 0.0887570342885659 0.9292750045383404 1.0 1.0 2 P04183 1
Signaling by erbb2 0.291367628354242 0.088293282414305 0.9296435779620756 1.0 1.0 14 P61586,Q9Y316,Q16543,P31749 4
Runx1 regulates estrogen receptor mediated transcription 0.3720349563046177 0.0842835854619212 0.9328309628652218 1.0 1.0 2 Q9HCL2 1
Pd 1 signaling 0.3673533083645428 0.0828059348388788 0.9340058500184408 1.0 1.0 2 Q06124 1
Telomere c strand synthesis initiation 0.2950640091134796 0.0775208806505657 0.9382091808979898 1.0 1.0 5 P49643,P49642 2
Uptake and function of anthrax toxins 0.3203606674387537 0.0774186382905467 0.9382905140688168 1.0 1.0 3 Q02750 1
Receptor mediated mitophagy 0.3184514517639632 0.0767214748520766 0.938845120429552 1.0 1.0 3 P19784,P67870 2
Signaling by wnt in cancer 0.2850488687470218 0.0762649161436442 0.9392083373858776 1.0 1.0 10 Q13362 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.296137927291423 0.0760854541933661 0.9393511124660234 1.0 1.0 48 P28072,P49721 2
Circadian clock 0.2781837768646696 0.0751726053558759 0.9400773804261602 1.0 1.0 11 Q9BWF3,Q15648,P63208,Q86X55,P04150,O75376,Q13616,P43490,P62136 9
Response of mtb to phagocytosis 0.2828071986851599 0.073428567856657 0.9414650850880631 1.0 1.0 13 P52294,P28482,Q14974,Q9UI12,P49840 5
Infection with mycobacterium tuberculosis 0.2828071986851599 0.073428567856657 0.9414650850880631 1.0 1.0 13 P52294,P28482,Q14974,Q9UI12,P49840 5
Aflatoxin activation and detoxification 0.2859818919762636 0.0679905689014276 0.9457931418387668 1.0 1.0 3 Q99735,O14880 2
Protein protein interactions at synapses 0.2768016644677508 0.0667405344895365 0.9467882643766186 1.0 1.0 12 Q9UJU6,Q14168,Q14254,Q96HC4,O14936 5
Signaling by met 0.2888869868632052 0.057936354829664 0.9537993247779526 1.0 1.0 19 P05556 1
Costimulation by the cd28 family 0.2863217284166462 0.0575109715225593 0.9541381665640372 1.0 1.0 17 Q13362,P30154,P42345 3
Purine salvage 0.2527617584781486 0.055018106006915 0.9561240391319812 1.0 1.0 5 P00813,P00492 2
Loss of function of mecp2 in rett syndrome 0.2485482449692067 0.0535741594883255 0.9572744446775364 1.0 1.0 5 Q96ST3 1
Protein methylation 0.2769615504845433 0.0529004755245591 0.9578112055147404 1.0 1.0 7 P13639,O60870,P15880,O60678,P55072,P11142 6
Phospholipid metabolism 0.2950583061125529 0.0524224184863711 0.9581921113054168 1.0 1.0 52 Q8IV08,P42356,Q8WUK0,P35790,Q13614,P40939,Q8NCC3 7
Runx2 regulates bone development 0.2581250000000096 0.0513887245701272 0.9590157693924825 1.0 1.0 6 Q13485,P28482,P07947,P27361,Q13951 5
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.2864819705789532 0.0460197122258322 0.9632945384689876 1.0 1.0 20 P28340,P40937,P27694,P15927,Q07864,P56282,Q9NRF9 7
Assembly of the orc complex at the origin of replication 0.2737492345008485 0.0450724070588046 0.9640495950405116 1.0 1.0 8 Q14974,O43913,O60684,Q9Y619 4
Glutathione conjugation 0.2695930419040065 0.0423733514722873 0.9662010717077636 1.0 1.0 14 P14550,P48507,Q96KP4,P48506 4
Translesion synthesis by polh 0.2611145898559803 0.0397386577966676 0.968301481540112 1.0 1.0 12 Q92890,P41440,P35250,P40937,P27694,Q8TAT6,P12004,P15927,P35251,P55072,P35249 11
Translesion synthesis by polk 0.2608695652173919 0.0343160084375553 0.9726251595006394 1.0 1.0 9 P41440,P35250,P40937,P27694,P12004,P15927,P35251,P35249 8
Cytosolic trna aminoacylation 0.2854541242336326 0.0334789039751646 0.9732926885893036 1.0 1.0 23 P26640,P07814,O43776 3
Collagen biosynthesis and modifying enzymes 0.2475743348982848 0.0278035144760753 0.9778188629010548 1.0 1.0 11 O15460,P50454,P23284,Q02809,O60568,Q8NBJ5,O75718,P13674,Q32P28,O00469 10
Nucleotide salvage 0.2386007269692842 0.0241118343917886 0.9807634035880732 1.0 1.0 7 P00813,P00492,P04183 3
Factors involved in megakaryocyte development and platelet production 0.2816308494534998 0.017560487180929 0.9859894784742724 1.0 1.0 41 Q8TDN4,P45973,Q13885,Q9H4M9,P47756,Q9BUF5,Q99661,Q9H0H5,Q9BVA1,Q02241 10
Dna damage bypass 0.2802526912248268 0.0149089706798493 0.9881048031509694 1.0 1.0 24 P28340,P40937,P27694,P15927,Q07864,P56282,Q9NZJ0,Q9NRF9 8
Signaling by notch 0.2918941838207709 0.0142150414442566 0.9886584198623488 1.0 1.0 59 P28072,P49721,Q92542 3