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Metabolism of lipids 0.4629623487662086 4.1446431125159195 3.40343349785055e-05 0.046888386253891 0.0480224466546726 200 Q9BWD1,O95772,Q8IV08,Q9NZJ7,P14324,O43772,Q9UG56,Q16850,Q15165,O15269,Q14849,Q15392,P50897,Q9NQZ5,P30536,Q8N2A8,Q9HCL2,Q9P035,Q9H2C2,Q9NRA0,P50416,Q96N66,P37268,P17900,P10619,P27544,Q13510,Q06520,Q06136,P09960,Q9UBM7,Q9H7Z7,P04062,Q15800,P43304,O95470,Q10713,Q9UMR5,O43808,P51648,O15254,Q9Y6B6,P38435,Q9BTU6,P16278,Q16836,P40939,Q8NF37,O75845,Q14739,Q14914,P07602,Q53GQ0,P23786,Q96G23,Q15067,P48449,P42356 58
Mitochondrial protein import 0.7093928138002908 3.770536964637553 0.000162896670975 0.20535986362075 0.0985855308876093 33 Q99595,P12236,O60830,O14925,Q9Y584,Q8N4H5,O75431,Q9Y512,Q9UJS0,Q9Y5J9,P21796,P06576,P12235,Q10713,Q13505,O75746,Q9NS69,O43615 18
Sphingolipid metabolism 0.72633306121769 3.627253985859265 0.000286451488402 0.332516728610647 0.1010457625338081 29 Q06136,Q9NZJ7,P04062,Q9NRA0,O43681,P07602,O95470,O15269,P51648,P17900,Q96G23,P10619,P27544,Q13510,P16278 15
Protein localization 0.64089937769125 3.555505508469104 0.0003772530402543 0.4128086141816007 0.1064608079597855 76 Q99595,O60830,Q9Y584,Q9BY49,P21796,P06576,O75746,P50402,Q9NS69,P09601,Q13190,P46379,Q9NR77,Q9Y5Y5,O14925,Q8N4H5,Q9UJS0,P05067,O14734,P12235,O43808,Q10713,O75381,Q9Y3D6,O15254,P51648,O43615,P12236,Q9Y512,P40855,Q13505,P28288,O43681,Q15067 34
Transport of small molecules 0.5176588803764285 3.5041647155982747 0.00045804194986 0.4760951798417683 0.1077161985421003 147 Q8WTV0,P16615,P28070,Q70HW3,Q96PU5,Q8TEL6,P21796,P08183,Q99797,P30519,P45880,Q93050,Q9Y6M7,O75027,P63218,Q15043,P02786,Q9BUN8,O15118,Q15904,Q4KMQ2,P09601,Q8WWC4,P20618,Q9NW15,P30825,P60900,P49721,P23634,P05023,P53985,Q9Y277,P12235,Q10713,Q9HD20,Q9Y6B6,Q9C0H2,P12236,Q9UBX3,Q8TB61,P28072,Q8N4V1,P28288,Q96QD8,Q9Y487,Q8TAD4 46
Slc mediated transmembrane transport 0.7702714192982245 3.39881147744555 0.0006767934972815 0.6152951739846132 0.1364222320948971 20 Q9UBX3,P53985,Q70HW3,Q8TB61,P12235,P30825,Q9Y6M7,Q96QD8,Q15043,Q8TAD4 10
Cholesterol biosynthesis 0.8023398365949642 3.2185130757188793 0.001288570955674 0.8378682574458707 0.227271702307007 16 Q9UBM7,Q15392,Q9BWD1,O75845,P14324,Q14739,Q15800,Q9H2C2,P37268,Q16850 10
Sphingolipid de novo biosynthesis 0.8595811008127464 3.1264689538017905 0.0017691918350914 0.917795113347124 0.247153488376647 12 Q06136,Q9NRA0,O95470,P51648,Q96G23,O15269 6
Rac2 gtpase cycle 0.6112677587317549 3.101292089210143 0.0019267812701226 0.9342115442317168 0.247153488376647 34 Q9Y512,Q86XL3,O15173,Q14739,P42167,Q13505,P50402,P02786,P49257 9
Ion channel transport 0.6180267029659949 2.8106808125863054 0.0049436802570079 0.9990815584424312 0.2675594401476604 28 P16615,Q15904,P23634,P05023,Q96PU5,Q4KMQ2,Q8TEL6,Q9NW15,Q93050,Q9HD20,Q9Y487,Q9C0H2 12
Pink1 prkn mediated mitophagy 0.8483586533382723 2.769205341194267 0.005619320724338 0.9996477687927736 0.2675594401476604 9 Q9NS69,P21796 2
Rhog gtpase cycle 0.5545573676195575 2.641727599455233 0.0082484366165476 0.999991596056984 0.2675594401476604 34 P84095,O15173,Q86XL3,Q13190,Q14739,P42167,Q7L576,P50402,P02786,P49257 10
Mitochondrial calcium ion transport 0.6954067046731722 2.612453932430503 0.0089894806594124 0.999997072943349 0.2675594401476604 16 Q9Y277,Q10713,P21796,P45880 4
Mitophagy 0.7560006719058237 2.601547855055387 0.0092804116269504 0.9999980657700964 0.2675594401476604 12 Q9NS69,P21796 2
Transport of inorganic cations anions and amino acids oligopeptides 0.8114998728041055 2.556903945229694 0.0105608374977008 0.9999996881006968 0.2761107010831535 10 Q9UBX3,P30825,Q9Y6M7,Q70HW3 4
Metabolism of steroids 0.5253488627439358 2.520954307794489 0.0117037048479309 0.999999938934898 0.2897180270250972 48 Q9UBM7,Q15392,Q9BWD1,P30536,O95772,P04062,O75845,P14324,Q9HCL2,Q15800,Q9H2C2,Q14739,P37268,Q16850,Q9Y6B6,P38435,P48449,Q14849 18
Glycosphingolipid metabolism 0.6508843093467647 2.4500756892855473 0.014282618798598 0.9999999984701216 0.3093620348229327 17 Q9NZJ7,P04062,P07602,P17900,O43681,P10619,Q13510,P16278 8
Class i peroxisomal membrane protein import 0.7838663706223388 2.4234912511455686 0.0153721235287878 0.999999999678655 0.3100509911146376 10 Q9NR77,O75381,O43808,P51648,Q9Y3D6,P28288,Q9Y5Y5 7
Cargo concentration in the er 0.6763549704365537 2.4022549057342317 0.0162943496139069 0.9999999999143456 0.3100509911146376 15 Q13190,P49755,Q15363,Q9Y6B6,Q9UBR2,P49257 6
Metabolism of porphyrins 0.7760332151488809 2.385287822373586 0.0170657636071611 0.999999999971685 0.3100509911146376 10 P36551,P09601,P30519,P22830 4
Gpcr ligand binding 0.7684431464831283 2.348106625822497 0.0188691188298975 0.999999999997878 0.3100509911146376 10 Q9BYT8,Q9NZJ7,P42892,P07602,P63218 5
Egr2 and sox10 mediated initiation of schwann cell myelination 0.91701164423479 2.340873403302527 0.0192386893838707 0.999999999998753 0.3100509911146376 5 Q16850 1
Iron uptake and transport 0.6199600345329918 2.330853794595335 0.0197610703981645 0.999999999999412 0.3100509911146376 18 P09601,P02786,P30519,Q93050 4
Rac3 gtpase cycle 0.5170798407547658 2.2683572693104925 0.0233074399743133 0.9999999999999964 0.3292062958261408 33 O15173,Q14739,P42167,Q7L576,P50402,P02786,P49257 7
Glycerophospholipid biosynthesis 0.5202077934596032 2.2416159230419193 0.0249862059696295 0.9999999999999996 0.3336871886782159 32 Q8N2A8,Q9NQZ5,Q8IV08,P40939,Q9HCL2,Q8NF37,Q9UG56,P43304,Q96N66,P35790 10
Phospholipid metabolism 0.4939649605229488 2.207108726072439 0.0273064642993037 1.0 0.347416448612635 52 Q8N2A8,Q9NQZ5,Q8IV08,P40939,Q9HCL2,Q8NF37,Q9UG56,P43304,Q96N66,Q10713,Q9BTU6,P42356 12
Cristae formation 0.5815665441094205 2.1563703311437448 0.0310547594495866 1.0 0.3862429820961319 19 Q9Y512,O75431,P24539,Q6UXV4,P06576,Q13505,Q5XKP0,O75964 8
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6698593340189105 2.138622844797347 0.0324662258158676 1.0 0.3924319501130743 12 P09601,Q13190,P46379,P51648,O43681,P50402 6
Rnd2 gtpase cycle 0.5890562119385473 2.1297669821833725 0.0331908558740405 1.0 0.3924319501130743 18 P02786,Q07065,P51648,Q15058 4
Class a 1 rhodopsin like receptors 0.7932338196304876 2.117716287308745 0.0341991026385302 1.0 0.3948625319703601 7 Q9NZJ7,Q9BYT8,P42892,P07602 4
Peptide ligand binding receptors 0.7932338196304876 2.117716287308745 0.0341991026385302 1.0 0.3948625319703601 7 Q9NZJ7,Q9BYT8,P42892,P07602 4
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.7032976088000407 2.0592411162075757 0.0394711461943404 1.0 0.4360418591191082 9 Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 5
Respiratory electron transport 0.4744370392090987 2.0319025160791777 0.0421635257816752 1.0 0.4507025369541196 50 Q9Y375,Q8N8Q8,O43819,O75880,O95168,P21912,Q9UDW1,O75251,P03886,O75306,P22695,O95299,Q9Y6N1,Q86Y39,Q7L592,O14949,P00403,Q16134,Q9P0J0,Q9H845,Q9BQ95,P13073,O43676 23
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4737915738478847 1.97550450073822 0.0482109243605697 1.0 0.4816604683488185 60 P06576,O75964,Q8N8Q8,O43819,O95168,P21912,Q9UDW1,O75251,P03886,O75306,P24539,O95299,P22695,Q86Y39,O14949,P00403,Q16134,Q9H845,P13073,O43676 20
Phosphorylation of the apc c 0.6672628238864783 1.9731956859965851 0.0484732717969753 1.0 0.4816604683488185 11 P53350,Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 6
Ire1alpha activates chaperones 0.5361782996000962 1.9617186223463592 0.0497952525148566 1.0 0.4913363727165222 22 O14773,Q9NWM8,O95070,P43307 4
Stimuli sensing channels 0.6846647983668407 1.9270258426912676 0.0539764094017651 1.0 0.5043755871913289 10 Q96PU5,Q4KMQ2,Q8TEL6,Q9NW15,Q9C0H2 5
Heme degradation 0.872259898685477 1.9045616035752868 0.0568370817083827 1.0 0.5140841172469748 4 P30519 1
Metabolism of folate and pterines 0.6966520051058043 1.8723797907265984 0.0611540789163989 1.0 0.5404499227280749 8 P00374,Q9H2D1 2
Amino acid transport across the plasma membrane 0.8581972399568958 1.8472231022565324 0.0647148124635701 1.0 0.5567841486957162 4 P30825 1
Apc c cdc20 mediated degradation of cyclin b 0.6429993509416555 1.8424436964898772 0.0654102751085325 1.0 0.5593569586553908 11 Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 5
Small interfering rna sirna biogenesis 0.7959444384964882 1.8321878186018064 0.0669234430936127 1.0 0.5635764832386654 5 O75569 1
Intra golgi traffic 0.6590589671448388 1.830990584800309 0.0671019483941146 1.0 0.5635764832386654 9 Q13190,O95249,O00461 3
Metabolism of steroid hormones 0.7261660491134393 1.8093261493105697 0.0704003488365057 1.0 0.5705523975664588 7 P30536,Q14849,O95772 3
Rhoa gtpase cycle 0.4476927916825314 1.7861561307858982 0.0740739818856417 1.0 0.5839016114002261 48 P51572,Q15904,P41440,O15173,Q13190,Q14739,P42167,Q14155,P30519,O15498,P28288,Q96HY6,P02786,P49257 14
Transferrin endocytosis and recycling 0.6319477898929141 1.7823310767124716 0.0746952577707624 1.0 0.5855278261919215 11 P02786,Q93050 2
Synthesis of pips at the golgi membrane 0.6521374237889399 1.7583960451202587 0.0786801455953905 1.0 0.5888914081288297 10 Q9NTJ5,Q9UBF8,Q10713,Q9BTU6,P42356 5
Pregnenolone biosynthesis 0.7785740307998699 1.7571441841899575 0.0788932361817305 1.0 0.5888914081288297 5 Q14849,O95772 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.5423935833580463 1.753256798329223 0.079557937484322 1.0 0.5888914081288297 17 P51572,P10321,Q03518,P55735,P27824,Q6P179,Q9Y6B6,Q9NZ08 8
Transport of vitamins nucleosides and related molecules 0.7364155590349216 1.716670122972866 0.0860394620511491 1.0 0.6072132657073311 6 Q8TB61,P12235 2
Synthesis of pg 0.8258040515607579 1.714162737653136 0.0864988422446304 1.0 0.6072132657073311 4 Q8IV08 1
Glycosaminoglycan metabolism 0.5730688024763516 1.703263015974556 0.0885188584972525 1.0 0.6122554379393298 14 P54802,Q8TB61,Q8NCH0,O43505,Q7LGA3,P16278 6
Transport of bile salts and organic acids metal ions and amine compounds 0.8194878201124288 1.688069446622575 0.091397898683363 1.0 0.6167375835780834 4 Q15043,P53985,Q8TAD4 3
G beta gamma signalling through pi3kgamma 0.760203968018001 1.6772859629460222 0.0934865761319865 1.0 0.6251637863612938 5 P63218,P31749 2
Heme biosynthesis 0.7221637083099309 1.652253767379711 0.098482829787593 1.0 0.6309224111930509 6 P36551,P22830 2
Ion transport by p type atpases 0.6244492899579869 1.6488372999816214 0.0991809711298046 1.0 0.6309224111930509 9 Q9HD20,P16615,P23634,P05023 4
Alpha oxidation of phytanate 0.7526786987957861 1.6444338867541095 0.1000866102404489 1.0 0.6309224111930509 5 O43808,P51648 2
Phase i functionalization of compounds 0.5514658623431751 1.644075492318028 0.100160609572816 1.0 0.6309224111930509 15 P07099,O43169,Q16850 3
Copi dependent golgi to er retrograde traffic 0.4320007081686803 1.6396969081594703 0.1010682021318667 1.0 0.6338099253691731 47 P52732,P24390,P49755,P62820,Q9Y3B3,Q13885,O15260,Q15363,Q9H0U4,Q6NUQ1,Q9P2W9,Q07866 12
Collagen formation 0.5566994060698655 1.603299952147942 0.108868447060904 1.0 0.6649929818308901 14 Q32P28,P13674,P07858 3
Activation of gene expression by srebf srebp 0.5180165784290566 1.5900080535483487 0.1118329897130081 1.0 0.6770479467171369 17 Q9UBM7,O75845,P14324,P37268,Q16850,P48449 6
Peroxisomal lipid metabolism 0.5425836082700248 1.5880213283032398 0.1122815163230404 1.0 0.6770479467171369 15 Q9BY49,O43808,O15254,P51648,Q15067 5
Regulation of cholesterol biosynthesis by srebp srebf 0.473958496511598 1.5829164242841065 0.1134405146979873 1.0 0.6798845546006685 24 Q9UBM7,O75845,P14324,Q9HCL2,P37268,Q16850,P48449 7
Attachment of gpi anchor to upar 0.7341455795064111 1.563210868312881 0.118003004625095 1.0 0.6823862275656112 5 Q969N2,Q9H490,Q92643,O43292 4
Synthesis of pc 0.6977168613409652 1.5410197153176937 0.1233119877468931 1.0 0.6911389418027352 6 Q8NF37,Q9NQZ5 2
Pi metabolism 0.484056284802323 1.5405137991103075 0.1234351618244431 1.0 0.6911389418027352 21 Q9NTJ5,Q8NEB9,Q9UBF8,Q10713,P42356,Q9BTU6,Q8NCE2 7
Zinc transporters 0.9116729088639284 1.525624165500439 0.1271034903228276 1.0 0.698820625488145 2 Q8TAD4 1
Metal ion slc transporters 0.9116729088639284 1.525624165500439 0.1271034903228276 1.0 0.698820625488145 2 Q8TAD4 1
Nr1h2 and nr1h3 mediated signaling 0.6635227192224638 1.5130970304315652 0.1302550138223828 1.0 0.698820625488145 7 O60341,Q9HCE1,O00767,Q8NB78 4
Peptide hormone metabolism 0.5168329866176257 1.4990720479597288 0.1338549421055559 1.0 0.701022424739086 16 Q9Y4I1,Q9UPT5,P67812,P35222,Q96A65,Q9UBR2,Q8TAD4 7
Mucopolysaccharidoses 0.7729056672943431 1.4943762640177671 0.1350773019140918 1.0 0.7025409258369453 4 P54802,P16278 2
Post translational modification synthesis of gpi anchored proteins 0.5876454748467707 1.452110982757459 0.1464707486326704 1.0 0.7332408259049942 9 Q92643,O43292,Q9Y2B2,Q9H490,Q969N2 5
Ros and rns production in phagocytes 0.5868561375417818 1.4478622959489644 0.1476555661848886 1.0 0.7332408259049942 9 Q93050 1
Rnd1 gtpase cycle 0.529133958471242 1.4332604448788615 0.1517834214865212 1.0 0.7378529203733288 14 P02786,P51648,Q15058 3
Synthesis of pa 0.590168573847618 1.4301592200838578 0.1526713266624586 1.0 0.7378529203733288 10 Q9HCL2,Q8N2A8,Q8NF37,P43304 4
Sulfur amino acid metabolism 0.581421667580706 1.418581316550202 0.1560211160577065 1.0 0.7378529203733288 9 Q13126 1
Hs gag degradation 0.9004058694973449 1.4050941160683743 0.1599932935472079 1.0 0.7378529203733288 3 P54802,P16278 2
Vitamin b5 pantothenate metabolism 0.7473454091192988 1.387374318759315 0.1653276517628534 1.0 0.7429213905649243 4 P49327,Q9NVE7,Q13057 3
Synthesis of pe 0.8735955056179772 1.368706762774851 0.171090955508625 1.0 0.7527483133523504 2 Q9UG56 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6896048585586082 1.3664990040319889 0.1717823932668014 1.0 0.7527483133523504 5 Q9HCE1,Q8NB78 2
Response to elevated platelet cytosolic ca2 0.4129493286473047 1.3491946448788994 0.1772744543983595 1.0 0.7672829912763353 33 O94919,Q9NZJ7,Q6UXV4,Q9NUQ9,Q8NBX0,O43852,Q9BWS9,P07602,Q12846,Q9Y6I9,Q08380 11
Gamma carboxylation hypusine formation and arylsulfatase activation 0.530619725761396 1.3407064062149727 0.180015793807315 1.0 0.7675172511043512 12 P38435,O60725,P49366,Q9HA64 4
Initiation of nuclear envelope ne reformation 0.4733451663519092 1.3404880615106936 0.1800867230787459 1.0 0.7675172511043512 18 Q86XL3,Q14739,P42167,Q8IXJ6,P50402 5
Pre notch processing in golgi 0.7351578704076458 1.3362480758766793 0.1814682019585862 1.0 0.7675172511043512 4 Q15363 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5218398790085934 1.3352114363638108 0.1818071548771906 1.0 0.7675172511043512 13 O43852,Q02818,Q07065 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5631901144210973 1.3200118674365462 0.1868310557884775 1.0 0.7751894026043713 9 Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 5
Rhod gtpase cycle 0.4275120148061632 1.3059009494455989 0.1915862436854625 1.0 0.7778055313850424 28 O15173,Q14739,Q9Y6M7,P50402,P49257 5
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.645526741832348 1.3010642738345533 0.1932364552437557 1.0 0.7778055313850424 6 P04439,P78310,P10321 3
Endosomal vacuolar pathway 0.7267409222418831 1.3009181844378277 0.1932864610087912 1.0 0.7778055313850424 4 P10321,Q9UIQ6 2
Collagen biosynthesis and modifying enzymes 0.5450925385113272 1.2995113550351034 0.1937684991689607 1.0 0.7778055313850424 11 Q32P28,P13674,O75718 3
Ca2 pathway 0.6739754195064929 1.2971220554876282 0.1945891938900921 1.0 0.7778055313850424 5 Q9HCE1 1
Apc cdc20 mediated degradation of nek2a 0.5217657565893524 1.2883579385432455 0.1976213932294892 1.0 0.7832690613674419 12 Q96DE5,Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 6
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5217657565893524 1.2883579385432455 0.1976213932294892 1.0 0.7832690613674419 12 Q96DE5,Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 6
Selective autophagy 0.4005098732571904 1.2766474672166728 0.20172673569977 1.0 0.7887444374051824 34 Q9NS69,P21796 2
Processing of smdt1 0.5401860926033091 1.2718169718560155 0.2034381573518562 1.0 0.7887444374051824 11 Q8WWC4,Q9H300,Q96TA2,Q10713,Q9Y4W6 5
Ptk6 regulates proteins involved in rna processing 0.8629409928192309 1.2617747315909071 0.2070298570605719 1.0 0.7960860217109688 3 Q07666,O75525 2
Abc transporters in lipid homeostasis 0.8464419475655429 1.257151324388935 0.2086988451911402 1.0 0.7960860217109688 2 P28288 1
Carboxyterminal post translational modifications of tubulin 0.6268472822880283 1.2146596365445177 0.2244959332017353 1.0 0.8335888467043383 6 Q13885,Q9UPW5,Q9BUF5 3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7045557873517544 1.2077940676650625 0.2271264839216358 1.0 0.8367505713144338 4 P12235 1
Synthesis of very long chain fatty acyl coas 0.5965529253917834 1.1901509986777916 0.2339870487072839 1.0 0.843540743459857 7 Q9P035,Q9NZ01,Q53GQ0 3
Biosynthesis of specialized proresolving mediators spms 0.8420745524343449 1.182200031131325 0.2371263403048273 1.0 0.843540743459857 3 P09960 1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5602345063759392 1.1786037097098427 0.2385560137628428 1.0 0.843540743459857 8 P07196,Q14168,Q15418 3
G2 m dna replication checkpoint 0.6939277619969867 1.1632253192450193 0.2447380963986374 1.0 0.8459669704878683 4 Q99640 1
Copii mediated vesicle transport 0.3874645936900884 1.1547013427944797 0.248212749463315 1.0 0.8459669704878683 34 Q9HCU5,Q13190,P49755,P62820,O15027,P55735,Q15363,O15498,Q9Y6B6,Q9UBR2,P49257 11
Intrinsic pathway of fibrin clot formation 0.8211610486891554 1.153904019454426 0.248539521113434 1.0 0.8459669704878683 2 P42785 1
O linked glycosylation of mucins 0.8333715242077575 1.1491078907000785 0.2505114950916984 1.0 0.8459669704878683 3 O43505 1
O linked glycosylation 0.8333715242077575 1.1491078907000785 0.2505114950916984 1.0 0.8459669704878683 3 O43505 1
Cytosolic sulfonation of small molecules 0.6899496322783176 1.1465575588985626 0.2515645256156003 1.0 0.8459669704878683 4 Q06520 1
Negative regulation of nmda receptor mediated neuronal transmission 0.6398090390978279 1.1452788653633297 0.2520936579469268 1.0 0.8459669704878683 5 P07196 1
Proton coupled monocarboxylate transport 0.8189762796504577 1.1450208092892442 0.2522005373875386 1.0 0.8459669704878683 2 P53985 1
Regulation of gene expression in beta cells 0.8152309612983766 1.1298097510185854 0.258556398520438 1.0 0.8459669704878683 2 P31749 1
Akt phosphorylates targets in the nucleus 0.8152309612983766 1.1298097510185854 0.258556398520438 1.0 0.8459669704878683 2 P31749 1
Wax and plasmalogen biosynthesis 0.6358524483854966 1.127707573290339 0.2594434382204804 1.0 0.8459669704878683 5 Q96K12,O00116 2
G1 s specific transcription 0.5145422818659608 1.12674774563701 0.2598491493083985 1.0 0.8459669704878683 11 P00374 1
Assembly and cell surface presentation of nmda receptors 0.5269357631609966 1.1229737702594946 0.2614486345685878 1.0 0.8459669704878683 9 P07196,O14936,Q14168,Q13885 4
Interleukin 4 and interleukin 13 signaling 0.4855012468965279 1.1140471227868785 0.2652589713253916 1.0 0.8459669704878683 13 P08670,P09601,P23458 3
Signaling by insulin receptor 0.4584784242226025 1.1122314220394327 0.2660386609468119 1.0 0.8459669704878683 16 Q93050 1
Coenzyme a biosynthesis 0.8108614232210034 1.112092665761459 0.2660983098308493 1.0 0.8459669704878683 2 Q9NVE7 1
Insulin receptor recycling 0.5305477306098211 1.1084770061063005 0.2676558642044044 1.0 0.8459669704878683 10 Q9Y487,Q93050 2
Cell surface interactions at the vascular wall 0.4464508635634612 1.1009183610125146 0.2709321900962236 1.0 0.8514149670952595 17 P14174,P35613,P53985,Q08722,P05026,Q9UNN8,Q92896 7
Synthesis of leukotrienes lt and eoxins ex 0.8195906493221703 1.0968649053643995 0.2727004520947818 1.0 0.8525984135578981 3 P09960 1
Integrin cell surface interactions 0.6769325879823345 1.092097014408009 0.2747904615889585 1.0 0.8545010896345353 4 Q08722 1
Fatty acyl coa biosynthesis 0.4641060259863981 1.0847667478598086 0.278024976479486 1.0 0.8589810924524898 15 P50897,Q9P035,Q9UKU0,Q53GQ0,Q9UMR5,O00767,Q9NZ01 7
Cd28 dependent pi3k akt signaling 0.8154854823602853 1.0813458609729911 0.2795432944040774 1.0 0.8589810924524898 3 P31749,P42345 2
Synaptic adhesion like molecules 0.621727851804682 1.0650575844362853 0.2868498719362129 1.0 0.8741796313218065 5 O95197 1
Activation of nima kinases nek9 nek6 nek7 0.6196726247917437 1.055954874323388 0.290988831860637 1.0 0.8754482766638783 5 P53350 1
Interferon gamma signaling 0.470947044089678 1.0253336351396485 0.3052057903720135 1.0 0.8873613412329094 13 P10321,P19474,P15260,P23458 4
Diseases of mitotic cell cycle 0.4956840486054625 1.020002518271644 0.3077272664216623 1.0 0.8873613412329094 11 Q96DE5,Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 6
Mitochondrial biogenesis 0.3686414455245657 1.0177671507664476 0.3087886264684296 1.0 0.8873613412329094 35 Q9Y512,O75431,P24539,Q6UXV4,P06576,P00367,Q13505,P48735,O00411,Q5XKP0,O75964 11
Insulin processing 0.4949394050849758 1.0157917394528588 0.3097285705149892 1.0 0.8873613412329094 11 Q9UPT5,Q96A65,Q9Y4I1,Q8TAD4 4
Long term potentiation 0.6581418220206106 1.0137841761495496 0.3106857475189215 1.0 0.8873613412329094 4 P07196 1
Ras activation upon ca2 influx through nmda receptor 0.6581418220206106 1.0137841761495496 0.3106857475189215 1.0 0.8873613412329094 4 P07196 1
Unblocking of nmda receptors glutamate binding and activation 0.6581418220206106 1.0137841761495496 0.3106857475189215 1.0 0.8873613412329094 4 P07196 1
Trafficking and processing of endosomal tlr 0.7973901260444213 1.0132278112443265 0.3109513593154913 1.0 0.8873613412329094 3 P07858 1
Transcriptional regulation by ventx 0.4529530867310888 1.0127586450783317 0.3111754583363628 1.0 0.8873613412329094 15 Q96DE5,Q9HCE1,Q9UJX3,Q9H1A4,Q13042,P30260,Q9UJX2 7
Neuronal system 0.3726822689016476 1.0098701198929867 0.3125575199682879 1.0 0.8873613412329094 51 P41440,O75955,P54646,O95197,O14936,Q14168,Q15418,P07196,Q14155,P21964,O75915,Q13885,P63218,Q96QD8,P51812 15
Gap junction assembly 0.65600747565911 1.004918671575412 0.3149360128673888 1.0 0.8873613412329094 4 Q13885,Q9BUF5 2
Transport of connexons to the plasma membrane 0.65600747565911 1.004918671575412 0.3149360128673888 1.0 0.8873613412329094 4 Q13885,Q9BUF5 2
Basigin interactions 0.580967558504482 1.0024900973192803 0.3161069469163879 1.0 0.8873613412329094 6 P35613,P53985 2
Unfolded protein response upr 0.3579176340753713 1.0015083338072277 0.3165811131149501 1.0 0.8873613412329094 37 Q9Y5M8,O95070,Q9HCU5,O14773,Q92945,P43307,Q9NWM8,O95453,P08243 9
Diseases of carbohydrate metabolism 0.5023974749319122 0.9895156200489154 0.3224109313603391 1.0 0.8873613412329094 9 P54802,P10253,P16278 3
Copi mediated anterograde transport 0.3700686133282287 0.9832562657893308 0.3254813288091811 1.0 0.8873613412329094 51 Q9UJW0,Q13190,P24390,O95249,P62820,Q9Y3B3,Q14789,Q13885,Q15363,Q9H0U4,O15498,O75935,P49755 13
Sumoylation of rna binding proteins 0.3829669983370368 0.9790525176092438 0.3275540310801443 1.0 0.8873613412329094 30 P07910,Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,P61978,Q8N1F7 10
Transmission across chemical synapses 0.3598988172303674 0.966005341255282 0.3340415083363943 1.0 0.8873613412329094 42 P54646,O14936,Q14168,Q15418,P07196,Q14155,P21964,O75915,Q13885,P63218,Q96QD8,P51812 12
Intraflagellar transport 0.4608500702883076 0.9638917973792716 0.3351001767073003 1.0 0.8873613412329094 13 Q92973,Q13885,Q7Z4L5,A0AVF1 4
Formation of fibrin clot clotting cascade 0.7839525444895385 0.963006098527186 0.335544462798339 1.0 0.8873613412329094 3 P42785,Q07021 2
Activation of ampk downstream of nmdars 0.5712187826178283 0.9576131323150402 0.338257874640909 1.0 0.8873613412329094 6 Q9BUF5,Q13885,P54646 3
Syndecan interactions 0.6438526142016774 0.9545748859107878 0.3397927224753476 1.0 0.8873613412329094 4 Q9Y296,O14936 2
Non integrin membrane ecm interactions 0.6438526142016774 0.9545748859107878 0.3397927224753476 1.0 0.8873613412329094 4 Q9Y296,O14936 2
Cyclin a b1 b2 associated events during g2 m transition 0.4833162456784828 0.9501498039727774 0.3420361399213609 1.0 0.8873613412329094 11 P53350,O95067,Q99640 3
Gastrin creb signalling pathway via pkc and mapk 0.5928605185846094 0.9376893110376914 0.3484040985421912 1.0 0.8873613412329094 5 Q15418 1
Creb phosphorylation 0.7748985326256608 0.9293758953575032 0.3526943153669943 1.0 0.8913873888305688 3 P51812,Q15418 2
Downregulation of erbb2 erbb3 signaling 0.7738941388468719 0.925656557741042 0.3546244909682958 1.0 0.89163936208539 3 P31749 1
Synthesis of dolichyl phosphate 0.7640449438202296 0.924845919399736 0.3550460609227499 1.0 0.89163936208539 2 Q86SQ9 1
Protein protein interactions at synapses 0.4585297971391151 0.9134478547333008 0.3610070467954034 1.0 0.89163936208539 12 O95197,Q14168 2
G alpha 12 13 signalling events 0.49193279655543 0.8999323040259729 0.3681562775913067 1.0 0.89163936208539 10 P63218,Q14155 2
The activation of arylsulfatases 0.7571785268414635 0.8978897501831767 0.3692443296608099 1.0 0.89163936208539 2 O43681 1
Rsk activation 0.6285881318037414 0.8917678308315159 0.372517387676524 1.0 0.89163936208539 4 Q15418 1
Suppression of apoptosis 0.6283111794751494 0.8906332700311941 0.3731259445181325 1.0 0.89163936208539 4 P23246,P49840 2
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7553058676654177 0.8905657066785952 0.3731622036273219 1.0 0.89163936208539 2 O00767 1
Signaling by ptk6 0.4422766173461338 0.8904764338584982 0.3732101168653536 1.0 0.89163936208539 14 Q07666,P04150,P23246,O75525 4
Cytochrome p450 arranged by substrate type 0.7623300028704412 0.8830121445894404 0.3772297098587414 1.0 0.89163936208539 3 Q16850 1
Regulation of ifng signaling 0.5795900500340733 0.8796245442899375 0.3790627380030025 1.0 0.89163936208539 5 P15260 1
The citric acid tca cycle and respiratory electron transport 0.3745668266215085 0.8752208488613337 0.3814537512426375 1.0 0.89163936208539 91 P21796,P06576,Q9Y375,O75964,Q9H9P8,O75880,Q8N8Q8,O43819,O95168,P21912,Q9UDW1,O75251,P03886,Q13423,P35613,P53985,O95299,P22695,O75306,P24539,Q7L592,Q86Y39,Q9Y6N1,O14949,P00403,Q16134,Q9P0J0,Q9H845,Q15120,P48735,Q9BQ95,P13073,O43676 33
Activation of nmda receptors and postsynaptic events 0.3904382393875368 0.864492883439339 0.3873171880608423 1.0 0.89163936208539 22 P54646,O14936,Q15418,Q14168,P07196,Q14155,Q13885,P51812 8
Prevention of phagosomal lysosomal fusion 0.6210921085299499 0.8611300930913642 0.3891663966997862 1.0 0.89163936208539 4 O14964 1
Purinergic signaling in leishmaniasis infection 0.5742364600483538 0.85631845194273 0.3918216576255875 1.0 0.89163936208539 5 P09601 1
The nlrp3 inflammasome 0.5742364600483538 0.85631845194273 0.3918216576255875 1.0 0.89163936208539 5 P09601 1
Inflammasomes 0.5742364600483538 0.85631845194273 0.3918216576255875 1.0 0.89163936208539 5 P09601 1
Diseases associated with n glycosylation of proteins 0.6197343111340843 0.8555968269983537 0.3922208256482071 1.0 0.89163936208539 4 Q9BT22 1
Platelet calcium homeostasis 0.6195103773784664 0.8546847595085001 0.3927256899779801 1.0 0.89163936208539 4 P16615,P23634 2
Reduction of cytosolic ca levels 0.6195103773784663 0.8546847595084993 0.3927256899779805 1.0 0.89163936208539 4 P16615,P23634 2
Intra golgi and retrograde golgi to er traffic 0.3729192547906393 0.8546166278216826 0.3927634192842268 1.0 0.89163936208539 87 P24390,O95249,Q86Y91,Q8TD16,Q7Z6M1,Q07866,P52732,Q13190,Q13885,O00461,Q9UJW0,Q9Y3B3,P62820,O15260,Q15363,Q9P2W9,P49755,Q10472,Q9H0U4,O75935,O15498,Q6NUQ1,Q15042 23
Cargo trafficking to the periciliary membrane 0.396750916733583 0.8465726305003979 0.3972333746766023 1.0 0.89163936208539 19 P50990,Q10713,A6NIH7 3
Heparan sulfate heparin hs gag metabolism 0.5706633570979838 0.8408066173366157 0.4004562793956845 1.0 0.8925502043610599 5 P54802,P16278,Q7LGA3 3
Formation of atp by chemiosmotic coupling 0.4763337218646895 0.8164084119788849 0.4142665870622766 1.0 0.8978957824037976 10 P06576,O75964 2
Circadian clock 0.4580160666235173 0.8082122486712126 0.4189684077512872 1.0 0.9041143169906428 11 P43490,P04150,P50416 3
Fatty acid metabolism 0.3597515256370759 0.8025056565166957 0.4222605176776064 1.0 0.9041143169906428 61 P09960,P50897,Q9H7Z7,Q16836,P40939,O43772,Q9P035,Q14914,P50416,Q53GQ0,O43808,Q9UMR5,O15254,P51648,P23786,Q15165,Q15067 17
Slc transporter disorders 0.3586385285171057 0.7927365442058406 0.4279313340823298 1.0 0.9097293998225418 31 P35613,P53985,Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 10
Neurotransmitter release cycle 0.5333213812401222 0.7849277203316279 0.4324959482070012 1.0 0.9097293998225418 6 Q96QD8,O14936 2
Beta oxidation of hexanoyl coa to butanoyl coa 0.599908535875038 0.7754570717075357 0.4380696225047478 1.0 0.9097293998225418 4 P40939 1
Beta oxidation of lauroyl coa to decanoyl coa coa 0.599908535875038 0.7754570717075357 0.4380696225047478 1.0 0.9097293998225418 4 P40939 1
Estrogen dependent nuclear events downstream of esr membrane signaling 0.5552758014682748 0.7744566948191088 0.4386607676865024 1.0 0.9097293998225418 5 P31749 1
Depolymerisation of the nuclear lamina 0.4674954166568684 0.7694200420157523 0.441643994485148 1.0 0.9099006513503256 10 P20700,P02545,P42167,P50402,Q9Y2U8 5
Golgi to er retrograde transport 0.3602243988227828 0.7574221929823768 0.448796964307943 1.0 0.9114906749518552 70 P52732,Q9UJW0,P24390,P49755,Q86Y91,Q8TD16,P62820,Q9Y3B3,Q13885,O15260,Q15363,Q10472,Q9H0U4,O75935,Q6NUQ1,Q15042,Q9P2W9,Q07866 18
Regulation of lipid metabolism by pparalpha 0.3738953085216694 0.7393893530922041 0.4596706054918602 1.0 0.9114906749518552 22 P23786,P37268,Q15067,Q06520 4
Chylomicron assembly 0.7125468164794319 0.7272003307356278 0.4671032436407523 1.0 0.9114906749518552 2 Q9Y6B6 1
Plasma lipoprotein remodeling 0.7125468164794001 0.7272003307355089 0.4671032436408251 1.0 0.9114906749518552 2 Q9BU23 1
Golgi cisternae pericentriolar stack reorganization 0.4594188039606315 0.7267529959905864 0.4673772820547341 1.0 0.9114906749518552 10 O95067,P53350,P62820 3
Tyrosine catabolism 0.7122347066167284 0.726039369846451 0.4678146357100083 1.0 0.9114906749518552 2 P16930 1
Complex i biogenesis 0.3599883747138422 0.7209172709993033 0.470960416025628 1.0 0.9114906749518552 27 O75306,O95299,Q9P0J0,O95168,Q7L592,Q86Y39,Q9H845,O75251,Q9BQ95,P03886,O43676 11
Beta oxidation of pristanoyl coa 0.5347275887323786 0.6872537577445127 0.4919228334774783 1.0 0.931154172392798 5 O15254 1
Signaling by flt3 fusion proteins 0.5774679901004506 0.6865388781879813 0.4923733566154564 1.0 0.931154172392798 4 Q14789 1
Synthesis of pips at the er membrane 0.7074617546050539 0.6864354383328276 0.4924385636054751 1.0 0.931154172392798 3 Q9NTJ5,P42356 2
Beta oxidation of butanoyl coa to acetyl coa 0.7063593943267192 0.6826074358679741 0.4948549341549717 1.0 0.931154172392798 3 P40939 1
Glutamate neurotransmitter release cycle 0.7038289849162973 0.6738419324130005 0.5004118125643298 1.0 0.931154172392798 3 Q96QD8 1
Ncam signaling for neurite out growth 0.5251483911277716 0.6472746886132166 0.5174541800824519 1.0 0.931154172392798 5 P28482,Q01082,P27361,Q13813 4
Synthesis of pips at the early endosome membrane 0.5023258806223078 0.6472162062463556 0.5174920240125709 1.0 0.931154172392798 6 Q9BTU6,Q13614,Q8NEB9 3
Transport to the golgi and subsequent modification 0.351864236519283 0.6446874366884041 0.5191297594519473 1.0 0.931154172392798 76 P24390,P04066,O95249,P55735,Q13190,Q14789,Q13885,Q9UBR2,Q9UJW0,P62820,Q9Y3B3,Q15363,Q9Y6B6,P49755,Q9HCU5,O15027,Q9H0U4,O15498,O75935,P49257 20
Extracellular matrix organization 0.3503367411657369 0.6426413554035448 0.5204568420707272 1.0 0.931154172392798 27 Q32P28,P35613,Q08722,O15460,O14936,P05067,P07858,O75718,P13674 9
Ra biosynthesis pathway 0.6936547182390183 0.6389116897657182 0.5228803828871464 1.0 0.931154172392798 3 O94788 1
Activation of smo 0.6875780274656923 0.6360848520236827 0.5247211181814526 1.0 0.931154172392798 2 P48729 1
Keratan sulfate keratin metabolism 0.5198269184149255 0.6252799515695533 0.5317873358167651 1.0 0.931154172392798 5 P16278 1
Er to golgi anterograde transport 0.3493036200873275 0.621160644109542 0.5344939311274794 1.0 0.931154172392798 75 Q9UJW0,Q9HCU5,Q13190,P24390,O95249,P49755,P62820,Q9Y3B3,Q14789,P55735,Q15363,O15027,O15498,Q9Y6B6,O75935,Q9UBR2,P49257 17
Cytoprotection by hmox1 0.3435022268493156 0.616093459204486 0.5378328387362936 1.0 0.9320830358822944 64 P00403,P49721,P28070,Q8N8Q8,O43819,P09601,P13073,P20618,P28072,P30519,Q8TCT9,P60900 12
Other interleukin signaling 0.5589618957096643 0.6150292525779443 0.5385354020866173 1.0 0.9320830358822944 4 Q12846 1
Arachidonic acid metabolism 0.4312729907615674 0.6105391028347003 0.5415047487504383 1.0 0.9324825914297444 9 Q15165,P09960,Q9H7Z7 3
Ras processing 0.5144005659713183 0.6030229047545603 0.5464934519817966 1.0 0.9392232164997744 5 O60725 1
Nuclear envelope breakdown 0.3219590491746709 0.6011428284797155 0.5477448595997065 1.0 0.9402287066851412 41 P57740,Q8NFH5,P53350,O95067,P20700,Q9BTX1,P42167,Q12769,Q99567,Q5SRE5,Q92621,P55735,P50402,Q8N1F7 14
Notch2 activation and transmission of signal to the nucleus 0.6763420724094874 0.5963682674351534 0.5509292344066261 1.0 0.943017381092201 2 Q92542 1
Vitamin d calciferol metabolism 0.5513586624836735 0.5862159317224868 0.5577304168054895 1.0 0.9492854259499948 4 P04062 1
Pexophagy 0.677177645956911 0.583499571992638 0.559557045089095 1.0 0.9499222790120796 3 Q13501,Q13315 2
Rhoc gtpase cycle 0.3284405401192939 0.5785435436149251 0.5628972081745891 1.0 0.9499222790120796 33 P41440,Q13190,Q14739,P42167,P28288,P02786,P49257 7
Ion homeostasis 0.4155652614008203 0.5762382256778614 0.5644541709481599 1.0 0.9499910475502612 11 P20020,P16615,P23634,P05023 4
Cardiac conduction 0.3982468386926638 0.5655718189778723 0.5716848895407654 1.0 0.9546122830083076 12 P20020,P16615,P23634,P05023 4
Pre notch processing in the endoplasmic reticulum 0.6654182272159792 0.5586185894074337 0.5764220504791133 1.0 0.9569926426349744 2 Q04721 1
Nuclear pore complex npc disassembly 0.3335079541069353 0.5548220899591186 0.579016356130206 1.0 0.9569926426349744 30 Q8NFH5,O95067,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 9
Ptk6 regulates rtks and their effectors akt1 and dok1 0.6613607990012684 0.5448284486264916 0.5858715106547514 1.0 0.9569926426349744 2 P31749 1
Rhoj gtpase cycle 0.3491486704483343 0.5389826498041671 0.5898988263872436 1.0 0.9569926426349744 21 P02786,P42167,O75323,Q9Y6M7 4
Signaling by mapk mutants 0.6557428214731577 0.5259513333466908 0.5989220210613824 1.0 0.9569926426349744 2 Q99956 1
Aspartate and asparagine metabolism 0.494807079277801 0.524273873487961 0.6000880659669279 1.0 0.9569926426349744 5 Q9UJS0,O75746 2
Complement cascade 0.6507490636704112 0.5093903134067052 0.6104786647066363 1.0 0.9569926426349744 2 P10909 1
Ripk1 mediated regulated necrosis 0.3879076634365392 0.5085373739240965 0.6110765357751777 1.0 0.9569926426349744 12 P49327,P41440,Q16543,O00560 4
Energy dependent regulation of mtor by lkb1 ampk 0.4260708478792919 0.5015094860173174 0.6160126034775044 1.0 0.9569926426349744 8 P49815,P54646,P42345 3
Regulation of beta cell development 0.5273163058373109 0.4976671406802115 0.6187186721014608 1.0 0.9569926426349744 4 P31749 1
G alpha i signalling events 0.3408911508025754 0.4967452628088089 0.6193686994075902 1.0 0.9569926426349744 22 Q9NZJ7,O43865,P07602,P05067,P63218 5
Biological oxidations 0.3153870470021604 0.4954563769158875 0.6202780075786014 1.0 0.9569926426349744 45 Q8TB61,P21964,Q9NUJ1,Q16850,P07099,O43169,Q06520 7
Polo like kinase mediated events 0.465929625577734 0.4923561488922209 0.6224675931981623 1.0 0.9569926426349744 6 P53350,Q99640 2
Regulation of kit signaling 0.5249843847595222 0.4893084605540909 0.6246233321356871 1.0 0.9569926426349744 4 P07947,P07948,P22681 3
Sumoylation of sumoylation proteins 0.3322897960506595 0.4884680894639936 0.6252183231601236 1.0 0.9569926426349744 26 Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 8
Regulation of glucokinase by glucokinase regulatory protein 0.3322897960506595 0.4884680894639936 0.6252183231601236 1.0 0.9569926426349744 26 Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 8
Sumoylation of ubiquitinylation proteins 0.3322897960506595 0.4884680894639936 0.6252183231601236 1.0 0.9569926426349744 26 Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 8
Regulation of mecp2 expression and activity 0.3833412307110884 0.4837179897328064 0.6285860241800956 1.0 0.9569926426349744 12 Q14739 1
Peroxisomal protein import 0.3347099665375015 0.470272656375485 0.6381602305238099 1.0 0.962578465561924 23 Q15067,Q9BY49,O15254,O75381 4
Class b 2 secretin family receptors 0.6372151108335884 0.4561647410301522 0.6482715179242786 1.0 0.970001178993804 3 P63218,Q9Y3E5 2
Beta oxidation of very long chain fatty acids 0.4506702511909809 0.4305034491613002 0.6668294582299104 1.0 0.9740456651850544 6 Q15067 1
Rac1 gtpase cycle 0.3051953481654882 0.4303167330228006 0.6669652566675965 1.0 0.9740456651850544 42 Q14739,P42167,Q7L576,O15498,P50402,P02786 6
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3694125059586607 0.4287639392616888 0.6680950241573509 1.0 0.9740456651850544 13 P09601,Q96J02 2
Tp53 regulates metabolic genes 0.2955108485575295 0.3961953500938255 0.6919609213398799 1.0 0.9891327675392776 37 P31749,O75880,O43819,Q8N8Q8,P13073,Q9HCE1,Q9Y6N1,P42345,P00403 9
Unwinding of dna 0.3935531955924405 0.3954029729601342 0.6925455153430038 1.0 0.9891327675392776 10 Q9Y248 1
Role of phospholipids in phagocytosis 0.6158950189848672 0.3931142992832228 0.6942350632733914 1.0 0.9891327675392776 3 Q8IV08 1
Aquaporin mediated transport 0.440580972824967 0.3908457926387362 0.6959112242353496 1.0 0.9891327675392776 6 Q99797 1
Downregulation of erbb2 signaling 0.3991600158523947 0.3786643080901251 0.7049371609901975 1.0 0.9921688540220536 8 P31749,Q16543 2
Rhoq gtpase cycle 0.3224470428823289 0.3555941762108541 0.7221445056648874 1.0 0.9976315351425415 21 P02786 1
Vitamin c ascorbate metabolism 0.600187265917602 0.3548837629893734 0.7226766730476144 1.0 0.9976315351425415 2 P00387 1
Fcgr activation 0.5983146067415721 0.3496726928947238 0.726584349378194 1.0 0.9992778136237216 2 P07948 1
Sialic acid metabolism 0.4290689927931659 0.3469512058985609 0.7286279764179888 1.0 0.9992778136237216 6 P16278 1
Pyruvate metabolism 0.3439971191847794 0.3422942342684192 0.732129474196044 1.0 1.0 15 P21796 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3126548552864591 0.3420232617248064 0.7323333864637147 1.0 1.0 26 P22626,Q13126,O14979 3
Vitamin b2 riboflavin metabolism 0.595505617977527 0.3419308336051033 0.7324029447988252 1.0 1.0 2 Q969G6 1
Translation of sars cov 1 structural proteins 0.4101468144955603 0.3319468124054014 0.7399294213836995 1.0 1.0 7 Q10472,P27824 2
Neurotransmitter receptors and postsynaptic signal transmission 0.2937575841438928 0.3261363460906041 0.7443211988759098 1.0 1.0 35 P54646,O14936,Q14168,Q15418,P07196,Q14155,Q13885,P63218,P51812 9
Recycling of eif2 gdp 0.4082525789309306 0.3244826432206179 0.7455726607271254 1.0 1.0 7 P49770,Q9UI10,Q9NR50,P20042,Q13144,P05198 6
Postmitotic nuclear pore complex npc reformation 0.3138957330722702 0.3242125820101403 0.7457770970600379 1.0 1.0 23 Q8NFH5,Q9BTX1,Q12769,Q92621,Q5SRE5,P55735,Q8N1F7,Q92973 8
Organelle biogenesis and maintenance 0.3249922845478062 0.3230951346708246 0.7466231948065039 1.0 1.0 97 P06576,Q96CS2,P50990,O43924,O75964,A0AVF1,O75431,Q6UXV4,Q92973,A6NIH7,P24539,P53350,Q7Z4L5,Q10713,Q5XKP0,Q9Y512,O94927,P00367,Q13505,P48735,O75935,O00411,Q15154 23
Interaction between l1 and ankyrins 0.587574149235086 0.3156146016702431 0.7522950532613555 1.0 1.0 3 Q12955,Q13813 2
Epha mediated growth cone collapse 0.38180112570356 0.3042086794362195 0.760968912780096 1.0 1.0 8 P35580,P07947,P61586,O75116,Q13464,P07948,P35579 7
Sema4d in semaphorin signaling 0.3818011257035599 0.3042086794362192 0.7609689127800963 1.0 1.0 8 P35580,P61586,O75116,Q13464,Q9NWH9,P63000,P35579 7
Export of viral ribonucleoproteins from nucleus 0.3046344495256903 0.2999546447759075 0.7642117517171221 1.0 1.0 28 Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 8
Interleukin 27 signaling 0.4676604398744829 0.2999364316440938 0.7642256444771971 1.0 1.0 4 P23458 1
Interleukin 35 signalling 0.4676604398744829 0.2999364316440938 0.7642256444771971 1.0 1.0 4 P23458 1
P75ntr negatively regulates cell cycle via sc1 0.5770911360798991 0.2934697463543392 0.7691631208949954 1.0 1.0 2 Q92769 1
Ngf stimulated transcription 0.5776126372878355 0.290224781788754 0.77164427858964 1.0 1.0 3 Q00535 1
G protein beta gamma signalling 0.3993908386729057 0.2902062093413837 0.7716584861648621 1.0 1.0 7 P63218,P31749 2
Plasma lipoprotein clearance 0.3425784625271016 0.288808043411747 0.7727282765334946 1.0 1.0 13 Q8WTV0 1
Cilium assembly 0.3080740362498562 0.2807294205323938 0.778917941470255 1.0 1.0 62 Q92973,P53350,O94927,Q7Z4L5,P50990,Q10713,O43924,O75935,Q15154,A6NIH7 10
Kinesins 0.3104747167781515 0.2700682474553278 0.7871077495921175 1.0 1.0 20 P52732,Q9H0B6,Q9Y496,Q02241,Q86Y91,Q13885,Q9BUF5,Q07866 8
Rho gtpase cycle 0.2751459762122029 0.2684904860810378 0.7883217971338632 1.0 1.0 160 O15173,P49257,Q14155,P62995,P30519,Q9Y6M7,Q07065,O75323,P50402,P02786,Q15904,Q16543,P08670,Q13190,Q15058,Q07021,P84095,P41440,Q86XL3,Q96DH6,P51648,Q96HY6,P51572,P07910,O95202,Q9Y512,Q14739,P42167,Q7L576,Q13505,P28288,O15498,P38159 33
Regulation of hmox1 expression and activity 0.2899935740467857 0.2611501470864488 0.7939767212232309 1.0 1.0 45 P49721,P28070,P09601,P28072,Q8TCT9,P60900 6
Signalling to ras 0.4532425719552964 0.2580844800468426 0.7963417090727438 1.0 1.0 4 P49137 1
Interleukin 12 signaling 0.2953945221129236 0.2422840275589094 0.8085600892988771 1.0 1.0 29 P22626,Q13126,O14979 3
Regulation of tp53 expression and degradation 0.3475514030366183 0.2419686509046405 0.8088044544710429 1.0 1.0 11 Q9Y243,P31749,Q13315,P42345 4
Cdt1 association with the cdc6 orc origin complex 0.2781134693074194 0.2200739046308597 0.8258135976894307 1.0 1.0 39 P49721,P28070,Q9Y619,P28072,P60900 5
Constitutive signaling by akt1 e17k in cancer 0.3593818593062019 0.2150081436019908 0.8297609693657142 1.0 1.0 8 Q9Y243,P31749,P49840,P42345 4
Sars cov 1 infection 0.3272033010312069 0.2149222341183345 0.8298279496195575 1.0 1.0 13 Q10472,Q8NEB9,P17844,P27824 4
Nuclear envelope ne reassembly 0.2860340391031384 0.207439293816597 0.8356667978932806 1.0 1.0 47 P57740,Q8NFH5,Q86XL3,O95067,Q14739,Q9BTX1,P42167,Q12769,Q92621,Q5SRE5,Q8IXJ6,P55735,Q13885,P50402,Q8N1F7,Q9BUF5,Q92973 17
Synthesis of pips at the plasma membrane 0.3271759549154603 0.2046956848612924 0.8378098920076957 1.0 1.0 12 P20339,Q01968,O15357,P61106,Q96T51,P20338,Q13614,Q8TBX8,Q9Y217,Q9BTU6,Q8NCE2 11
Trans golgi network vesicle budding 0.2773939492635936 0.2034557978396711 0.8387787912978077 1.0 1.0 40 Q9H3P7,Q9Y5X1,Q0IIM8,Q12846,P05067,Q14789,Q9UBR2,P02786 8
Pyruvate metabolism and citric acid tca cycle 0.28332204897595 0.2028639115530898 0.8392414021474035 1.0 1.0 33 Q13423,P21796,P21912 3
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.5349563046192249 0.1985760114707805 0.8425944199685487 1.0 1.0 2 P52292 1
Camk iv mediated phosphorylation of creb 0.5349563046192249 0.1985760114707805 0.8425944199685487 1.0 1.0 2 P52292 1
Golgi associated vesicle biogenesis 0.2862734053509911 0.1976277946094262 0.8433362867314089 1.0 1.0 31 Q0IIM8,Q9H3P7,Q9Y5X1,P02786 4
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.3725277581660532 0.1934922875883141 0.846573445542979 1.0 1.0 7 Q15067,O14734 2
Abc family proteins mediated transport 0.2854680017219915 0.1932860194632143 0.8467349747321 1.0 1.0 48 P49721,P28070,P20618,P08183,P28072,O75027,P60900,Q9BUN8 8
Mastl facilitates mitotic progression 0.426920674578385 0.1888360769655289 0.8502212951710497 1.0 1.0 4 P30153,P30154,P06493 3
Sema4d induced cell migration and growth cone collapse 0.3815625000000093 0.1843886567110754 0.8537085678876477 1.0 1.0 6 P35579,P35580,P61586,Q13464,O75116 5
Met activates pi3k akt signaling 0.5246566791510601 0.1789377414029433 0.8579865876589257 1.0 1.0 2 Q9NWH9 1
Role of lat2 ntal lab on calcium mobilization 0.52465667915106 0.1789377414029431 0.8579865876589259 1.0 1.0 2 P07948 1
Amino acids regulate mtorc1 0.3162040733123324 0.176504318325156 0.8598977564096244 1.0 1.0 14 Q9NXC5,P55735 2
Signal attenuation 0.5248204807992436 0.1738447116287287 0.8619875045666738 1.0 1.0 3 P28482,P27361 2
Mecp2 regulates transcription of neuronal ligands 0.5238838588822906 0.1720714846372642 0.8633813303299829 1.0 1.0 3 P51608,Q13547 2
Platelet adhesion to exposed collagen 0.5152933832709101 0.1623206825561987 0.8710533283360382 1.0 1.0 2 P07948 1
Met interacts with tns proteins 0.5152933832709101 0.1623206825561987 0.8710533283360382 1.0 1.0 2 Q9NWH9 1
Met activates ptk2 signaling 0.5152933832709101 0.1623206825561987 0.8710533283360382 1.0 1.0 2 Q9NWH9 1
Free fatty acids regulate insulin secretion 0.5009363295880139 0.1391188684379478 0.8893562183549926 1.0 1.0 2 O95573 1
Platelet homeostasis 0.3083597879727433 0.1321349572389674 0.8948775464387742 1.0 1.0 13 P63218,P20020,P16615,P23634 4
The phototransduction cascade 0.4011060538884354 0.1306777345289333 0.89603024655479 1.0 1.0 4 P53582 1
Myoclonic epilepsy of lafora 0.4928214731585505 0.1272107230603706 0.8987736185594384 1.0 1.0 2 P13807 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3733853963976544 0.1271049211039081 0.8988573565783229 1.0 1.0 5 O14654 1
Interleukin 12 family signaling 0.2743763417486528 0.1243606227295679 0.9010297497729176 1.0 1.0 32 P22626,Q13126,O14979 3
Autophagy 0.2810575495807035 0.1210892015278821 0.9036203821705078 1.0 1.0 52 Q9NS69,P21796 2
Rna polymerase iii transcription initiation from type 1 promoter 0.3066721748959135 0.1193475903651769 0.9049999812457998 1.0 1.0 12 Q12789,Q9Y5Q8 2
P38mapk events 0.491259024545674 0.1168852187815152 0.9069510115607228 1.0 1.0 3 P49137 1
Rhot1 gtpase cycle 0.4715980024968777 0.1000635659226472 0.9202938602965144 1.0 1.0 2 Q8IXI2 1
Synthesis of pips at the late endosome membrane 0.3606096895853489 0.0979584244317264 0.9219653070275248 1.0 1.0 5 Q13614,Q8NEB9 2
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.3838226108682046 0.0974268434702226 0.922387428120458 1.0 1.0 4 P46108,P61586,Q96JJ3 3
Runx1 regulates expression of components of tight junctions 0.4695852359172522 0.0872514916767435 0.930471610939158 1.0 1.0 3 Q16625 1
Regulation of signaling by cbl 0.3453125000000084 0.0850564799362151 0.932216488851146 1.0 1.0 6 P07947,P46108,P62993,P07948,P22681 5
Tight junction interactions 0.4550561797752795 0.0827235060302996 0.934071393819794 1.0 1.0 2 Q8N3R9 1
Adenylate cyclase inhibitory pathway 0.462379019669052 0.0786073473789809 0.937344943262528 1.0 1.0 3 P04899,P63096 2
Rho gtpases activate nadph oxidases 0.3161350844277682 0.0705829858745381 0.9437296519405852 1.0 1.0 8 P27361,P05771,Q8NEB9,Q99570,P28482,Q16539,P63000 7
Metabolism of fat soluble vitamins 0.3471108426054635 0.0702813709373449 0.9439697096761146 1.0 1.0 5 Q8N0U8 1
Plasma lipoprotein assembly remodeling and clearance 0.2796387337558969 0.0691303280079172 0.944885880508227 1.0 1.0 17 Q8WTV0,O15118 2
Pi3k akt signaling in cancer 0.289768336663852 0.0651784897652529 0.9480318873859443 1.0 1.0 14 P84095,P31749,P49840,Q9Y243,P42345 5
Regulation of tp53 activity through association with co factors 0.4460820867547199 0.0611935196422867 0.9512050906388902 1.0 1.0 3 P31749 1
Ns1 mediated effects on host pathways 0.2648624104014249 0.0603428240834234 0.9518825953804612 1.0 1.0 32 Q8NFH5,Q9BTX1,Q12769,Q99567,Q5SRE5,Q92621,P55735,Q8N1F7 8
Dna damage reversal 0.3328125000000091 0.0564891973268325 0.95495210106899 1.0 1.0 6 Q9C0B1,Q6P6C2,Q8N3C0,Q9H1I8,P16455 5
Miro gtpase cycle 0.3373945641987 0.0523583501044564 0.9582431603715555 1.0 1.0 5 Q8IXI1,Q8IWA4,P52306,Q8IXI2 4
Notch3 activation and transmission of signal to the nucleus 0.4104244694132321 0.0504783310150077 0.9597412167322584 1.0 1.0 2 Q92542 1
Apoptotic factor mediated response 0.3200919102467309 0.0424555375142409 0.9661355556914744 1.0 1.0 7 O14727 1
Mhc class ii antigen presentation 0.27516343107116 0.0419211618148854 0.9665615465364964 1.0 1.0 56 P52732,Q9UJW0,Q99538,P55735,Q13885,P07858,O75935,Q9Y6B6,P10619,Q07866 10
Cd163 mediating an anti inflammatory response 0.3838951310861408 0.0393954089179327 0.96857514022257 1.0 1.0 2 P35579 1
Activated ntrk2 signals through cdk5 0.3835830212234693 0.0392932418571393 0.9686565946737946 1.0 1.0 2 Q00535 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.3804619225967526 0.0383035674630938 0.969445646451082 1.0 1.0 2 P11802 1
Activation of the pre replicative complex 0.2677338355304404 0.0379593852388964 0.9697200645567164 1.0 1.0 20 P49643,P33992,P27694,P33993,O75419,P25205,Q14181,Q14566,P49736,Q9NR33,Q9NRF9,P15927,P56282,Q07864,P33991,O43913,P49642,Q9Y619,Q9UBD5 19
Cd28 co stimulation 0.3013719056958174 0.0373067419778629 0.9702404299156184 1.0 1.0 10 P31749,P42345 2
Er quality control compartment erqc 0.3745318352059911 0.036577198380823 0.9708221244178784 1.0 1.0 2 Q9UBV2 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.3021705865002249 0.0329536689026551 0.9737115344150528 1.0 1.0 8 Q9UQ84 1
Resolution of d loop structures 0.3021705865002249 0.0329536689026551 0.9737115344150528 1.0 1.0 8 Q9UQ84 1
Maturation of sars cov 1 nucleoprotein 0.3305243445692868 0.028716271581183 0.9770908788743002 1.0 1.0 2 P49840 1
Caspase activation via extrinsic apoptotic signalling pathway 0.3974191911655327 0.0250353404538754 0.9800267748298376 1.0 1.0 3 Q9UKG1 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.3840149859506642 0.0186156135082103 0.9851477472161324 1.0 1.0 3 P54646,P54619 2
Signaling by hippo 0.3096518688558197 0.0115760602965653 0.9907638464969646 1.0 1.0 6 Q07157 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.3084219323933903 0.0086742034976889 0.9930790737425396 1.0 1.0 5 P04439,Q10567,Q6VY07 3
Transcriptional regulation by mecp2 0.2634543867679526 0.002827372139206 0.9977440864281252 1.0 1.0 17 Q14739 1
Pp2a mediated dephosphorylation of key metabolic factors 0.3012800499531628 0.0003416672467554 0.9997273889841858 1.0 1.0 3 P30153,P30154 2
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