Upload folder using huggingface_hub

interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:05727a6553eb5416130d278f52b868958e129295e3f09ccabd1d6ff278d15875
+size 84287

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3426,
+    "annotations_size": 58,
+    "title": "Average number of proteins per term",
+    "value": 2.810344827586207
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C131/C131_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.4972246567338746	0.1569159821911239	0.8753110639296817	1.0	0.99545179819454	3	P00390,P09622	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.5412726155630728	0.048925587170424	0.9609785976627192	1.0	0.99869157944189	5	Q16763	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AKT3", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDC34", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MARK3", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME6", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["DLD", "GSR", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:4f329d6f50d5999f8cde27c129889016fecef37a147842f4d9fe930f0d0dd468
+size 80027

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3426,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 5.225806451612903
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C131/C131_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.561039719626179	0.5789960644114294	0.5625918287190457	0.9999999999926296	0.7266811120954341	2	P34897	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.6677418028149504	0.3454611398292567	0.7297477199498283	1.0	0.8378584932757288	41	O95302,O43852,P41208,Q9NWM8,Q14257,Q96AY3,P0DP25,Q02818,Q9Y680,P80303,Q15293	11

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "AKT3", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NEK1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "NUCB1", "NUCB2", "RCN1", "RCN2", "SHMT2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Thioredoxin, conserved site [IPR017937]", "1": "DnaJ domain, conserved site [IPR018253]", "2": "Guanylate kinase, conserved site [IPR020590]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:52829b56376c091d6223cab5412c4797a50f59016055ecda335c8b62e96b5b5a
+size 110010

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3426,
+    "annotations_size": 284,
+    "title": "Average number of proteins per term",
+    "value": 2.8450704225352115
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C131/C131_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.8679906542056095	2.0690513130934765	0.0385412717720847	0.9999857995022706	0.1391030540959857	2	Q16539	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.9120654396728058	1.8102848002157816	0.0702516329334099	0.999999998962996	0.1975392450800834	3	P27824,P27797	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.7608060747663618	1.542290161802536	0.1230030986058472	1.0	0.2863350820004968	2	P50570	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.8209173239848163	1.4052846869250817	0.1599366400285136	1.0	0.3267770199143731	3	O00469,O60568	2
+Haem oxygenase conserved site [IPR018207]	0.6927570093458006	1.203757555458852	0.2286832992919745	1.0	0.4329737133261384	2	P09601	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.7280163599182049	0.9933713101304408	0.3205290376454104	1.0	0.5396856731454129	3	P09429,O15347	2
+Serpin, conserved site [IPR023795]	0.7277242185217698	0.9920954178628772	0.3211509815548408	1.0	0.5396856731454129	3	P35237,P50454	2
+Clathrin adaptor complex, small chain [IPR000804]	0.6877008472100601	0.8196479791931264	0.4124168135915576	1.0	0.6100332034375122	3	P53680,Q92572	2
+CBX family C-terminal motif [IPR033773]	0.5654205607476742	0.5981325247824714	0.5497515096773984	1.0	0.7194904550616643	2	Q9HC52	1
+Intermediate filament protein, conserved site [IPR018039]	0.8358616450743598	0.5879099240244082	0.5565927549181535	1.0	0.723541858902824	8	P08670,P07196,Q16352,P07197	4
+Thioredoxin, conserved site [IPR017937]	0.8036861112472983	0.5085512846010167	0.6110667829534708	1.0	0.7803355548358265	11	P13667,Q96JJ7,Q8NBS9,P30101,Q15084,O95881,P07237,O43396,Q8IXB1	9
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8084842952423913	0.5061828829467938	0.6127282701703849	1.0	0.7803355548358265	8	P49721,P20618,P28074,P28070	4
+Ubiquitin interacting motif [IPR003903]	0.6590685070003512	0.4483709912123569	0.653885473865089	1.0	0.8109322033960056	4	Q92783	1
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.7092579397810388	0.4026358209319782	0.6872161538074824	1.0	0.8412473606953663	5	P48735,O75874	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.4997079439252423	0.3338015346650313	0.7385293252911749	1.0	0.888738679587685	2	P13861	1
+Arrestin, conserved site [IPR017864]	0.4985397196261814	0.329623779760648	0.7416842522812177	1.0	0.888769314969898	2	P49407	1
+Hexapeptide transferase, conserved site [IPR018357]	0.4859813084112283	0.2860887819010853	0.7748101233862956	1.0	0.9168586460071164	2	Q96IJ6	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6824052932431302	0.1877666714834941	0.851059563328624	1.0	0.978546218564086	6	Q14566,P25205	2
+IMP dehydrogenase / GMP reductase, conserved site [IPR015875]	0.4992696465089217	0.1616998672002079	0.871542209123586	1.0	0.9900719495643936	3	P12268,Q9P2T1	2
+DnaJ domain, conserved site [IPR018253]	0.663834843341683	0.154761709367563	0.8770091789350636	1.0	0.9923131745719443	11	P25685,Q99543,P31689,Q96EY1,Q9UBS4,Q9Y2G8,Q8WXX5,O60884,Q96KC8	9
+Guanylate kinase, conserved site [IPR020590]	0.6575340393344253	0.1414799633527037	0.8874907877478879	1.0	0.995261472198522	8	Q14168,O14936,Q00013,Q12959,Q8N3R9	5
+Methylthiotransferase, conserved site [IPR020612]	0.4085864485981398	0.0811485518946982	0.935323814145666	1.0	0.995261472198522	2	Q96SZ6	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.4077102803738429	0.0794971234580714	0.9366372195215742	1.0	0.995261472198522	2	P82675	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.4991233196960711	0.0616790746846291	0.9508184042182244	1.0	0.9982739096063884	4	P46940,Q86VI3,Q13576	3
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5814795860138509	0.0316423344283694	0.974757282287323	1.0	1.0	8	O94788,P30837	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB1", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPH7", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH1", "IMPDH2", "INA", "ING5", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF169", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAF5", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "UIMC1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ALDH1A2", "ALDH1B1", "AP2S1", "AP3S1", "ARRB1", "CALR", "CANX", "CASK", "CBX8", "CDK5RAP1", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC16", "DNAJC2", "DNAJC9", "DNM2", "GMPPA", "GMPR2", "HMGB1", "HMGB3", "HMOX1", "IDH1", "IDH2", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "MAPK14", "MCM3", "MCM6", "MPP1", "MPP2", "MPP5", "MRPS5", "NEFL", "NEFM", "P4HB", "PDIA3", "PDIA4", "PDIA6", "PLOD2", "PLOD3", "PRKAR2A", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "SERPINB6", "SERPINH1", "STAM", "TMX3", "TXNDC12", "TXNDC5", "TXNL1", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "2": "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "3": "EF-hand domain [IPR002048]", "4": "Thioredoxin domain [IPR013766]", "5": "Rab-GTPase-TBC domain [IPR000195]", "6": "Guanylate kinase-like domain [IPR008144]", "7": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "8": "DnaJ domain [IPR001623]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:1bb7edae5710c929539bd4754e5f6a97645719a9797acf5b1b1cff131c8dbab0
+size 494132

interpro_domain/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+RNA recognition motif domain [IPR000504]	51	124	3.2411577844381747	0.0011904527242838	39.713592233009706	116.0	0.2316956716939257	0.5316884276370477	13.873754985119357	5.729331786381952	1.713447249572458	0.3950212299678106	0.4983457078164708	0.5779929548395715	0.2388618381863343	8.262243554595894e-05	9.693914555544104e-12

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3426,
+    "annotations_size": 2802,
+    "title": "Average number of proteins per term",
+    "value": 2.245895788722341
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C131/C131_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,198 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+RNA recognition motif domain [IPR000504]	0.4524915150566888	3.2411577844381747	0.0011904527242838	0.9644791551705852	0.0400302129619425	124	P38159,P84103,P35637,P52272,Q16629,Q13242,Q13595,Q13283,P55795,Q9P2K5,Q07955,Q86U42,O14979,O43390,P98179,Q8WXF1,Q86V81,Q13151,A0AV96,P43243,P23588,Q14103,Q9UKA9,Q8N684,Q92804,O43251,Q8WXF0,Q13243,Q15056,P31943,O60506,P22626,Q99729,Q9UN86,Q14011,O75494,P62995,P51991,Q9Y6M1,P98175,Q9BWF3,P05455,P31942,P11940,P23246,Q01844,Q93062,Q96E39,Q9BY77,P52597,Q8IXT5	51
+Prenylcysteine lyase [IPR010795]	0.9827686915887852	2.6121185394948805	0.0089983048049215	0.9999999999899892	0.0524183993001877	2	Q9UHG3	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.9792640186915892	2.5959138972432334	0.0094339702853685	0.99999999999708	0.0530409338251519	2	Q15418	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.9754672897196268	2.578331331525408	0.0099278753761227	0.999999999999278	0.0548676662798734	2	P98179	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.9740070093457948	2.5715611875868203	0.010124112335845	0.9999999999995858	0.055129710183347	2	O15460	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.9439252336448608	2.4311593562305553	0.0150505933603153	1.0	0.066853750904204	2	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.9439252336448608	2.4311593562305553	0.0150505933603153	1.0	0.066853750904204	2	P04439	1
+Immunoglobulin C1-set [IPR003597]	0.9439252336448608	2.4311593562305553	0.0150505933603153	1.0	0.066853750904204	2	P04439	1
+START domain [IPR002913]	0.9392523364485988	2.4091901213759597	0.0159879668255387	1.0	0.0693471873764078	2	Q9NQZ5	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9342873831775712	2.385801348503202	0.0170419537865154	1.0	0.0719149917316508	2	Q8N2A8	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.915011682242992	2.2945485904393297	0.0217590073694544	1.0	0.0835549063642319	2	O60506	1
+Legume-like lectin [IPR005052]	0.8799649532710307	2.126852835205084	0.0334323127251439	1.0	0.1088932536666352	2	P49257	1
+OTU domain [IPR003323]	0.8723714953271029	2.090227064383066	0.0365974074524559	1.0	0.1139399285353129	2	Q96FW1	1
+XPC-binding domain [IPR015360]	0.8720794392523397	2.088816375647467	0.0367242557349554	1.0	0.1140813354427328	2	P54725	1
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.8720794392523397	2.088816375647467	0.0367242557349554	1.0	0.1140813354427328	2	P54725	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.8682827102803772	2.070464053996024	0.0384089088598615	1.0	0.11703901051061	2	P51114	1
+PITH domain [IPR010400]	0.8577686915887865	2.019514610863927	0.0434337602575158	1.0	0.126508727901829	2	O43396	1
+RBM1CTR [IPR012604]	0.8525116822429948	1.993971089021748	0.0461552141033343	1.0	0.1310303038678245	2	P38159	1
+Cold-shock (CSD) domain [IPR019844]	0.947690208195728	1.9665876125356083	0.0492307727271863	1.0	0.1368498265690239	3	P67809	1
+Peptidase M20, dimerisation domain [IPR011650]	0.8460864485981314	1.962690642024484	0.0496821311463939	1.0	0.1378310212595999	2	Q8IYS1	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.8428738317757054	1.947025935695959	0.0515316253658091	1.0	0.1403222684888213	2	P55010	1
+Zinc finger, CHHC-type [IPR012996]	0.9406952965235192	1.936017002194869	0.052865618639537	1.0	0.1429249655705537	3	P52597,P55795	2
+CARG-binding factor, N-terminal [IPR012956]	0.8341121495327126	1.9042233421257944	0.0568811029565494	1.0	0.1504646747917347	2	Q99729	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8314836448598143	1.8913600969934805	0.0585762913954899	1.0	0.1535367338542214	2	Q969X5	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8314836448598143	1.8913600969934805	0.0585762913954899	1.0	0.1535367338542214	2	Q969X5	1
+Protein Kinase B, pleckstrin homology domain [IPR039026]	0.8288551401869202	1.8784867400919745	0.060314609341046	1.0	0.1560494324779418	2	P31751	1
+NudC N-terminal domain [IPR025934]	0.8265186915887877	1.8670353901747472	0.0618966458751213	1.0	0.1592602403508631	2	Q9Y266	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.9068068945369598	1.7870923476566016	0.0739225641027538	1.0	0.1774901667659952	3	Q5BKZ1,O43823	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8054906542056113	1.7636382917705309	0.0777928965150449	1.0	0.1833738840198034	2	Q96AE4	1
+Marvel domain [IPR008253]	0.8043224299065443	1.757877373788487	0.0787683764508235	1.0	0.183924159012673	2	Q16625	1
+SUN coiled coil domain 2 [IPR040994]	0.8037383177570137	1.754996299181334	0.0792599407823784	1.0	0.1847640216907024	2	Q9UH99	1
+HD/PDEase domain [IPR003607]	0.7961448598130902	1.7175060918059972	0.085886742345616	1.0	0.1922020651947361	2	O60658	1
+MHC class I-like antigen recognition-like [IPR011161]	0.8860711569846488	1.695375346403054	0.0900042396790743	1.0	0.1982640562741873	3	P04439	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.7754088785046767	1.614821494289081	0.1063493570140454	1.0	0.2220498497416955	2	Q5T9A4	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.9582115721800162	1.6026199495364335	0.1090185865837694	1.0	0.22610664663784	4	Q32P28,P13674,O15460	3
+Sorting nexin, N-terminal [IPR005329]	0.7675233644859849	1.5756730707237314	0.1151011666411139	1.0	0.234214574385186	2	O60749	1
+BSD domain [IPR005607]	0.7654789719626225	1.565516126367792	0.1174619391511364	1.0	0.2383902023169474	2	Q9NW68	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.945061367621276	1.5496020511604092	0.1212370603505683	1.0	0.2426473165016375	4	P08670,P07196,Q16352	3
+GTPase effector domain [IPR020850]	0.7608060747663618	1.542290161802536	0.1230030986058472	1.0	0.2451313529826343	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.7608060747663618	1.542290161802536	0.1230030986058472	1.0	0.2451313529826343	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.7608060747663618	1.542290161802536	0.1230030986058472	1.0	0.2451313529826343	2	P50570	1
+Histidine kinase domain [IPR005467]	0.8477943324569169	1.525187493775947	0.1272123390283841	1.0	0.2511973037050967	3	Q15120,O14874	2
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.8477943324569169	1.525187493775947	0.1272123390283841	1.0	0.2511973037050967	3	Q15120,O14874	2
+EB1, C-terminal [IPR004953]	0.7426985981308454	1.4521880211964122	0.1464493325093601	1.0	0.2746660171962697	2	Q15555	1
+Domain of unknown function DUF4749 [IPR031847]	0.7412383177570139	1.4449169366616343	0.1484812184255739	1.0	0.2767290680499777	2	Q96HC4	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.8209173239848163	1.4052846869250817	0.1599366400285136	1.0	0.2896906809112961	3	O00469,O60568	2
+Rap/Ran-GAP domain [IPR000331]	0.7257593457943974	1.3678325805587843	0.1713644869479413	1.0	0.3054473870407962	2	Q96FS4	1
+LEM-like domain [IPR013146]	0.7242990654205658	1.3605612380454537	0.1736523881230158	1.0	0.3087398423354635	2	P42167	1
+PDZ-associated domain of NMDA receptors [IPR019583]	0.723714953271035	1.357652824347961	0.1745738727323487	1.0	0.3090056799722306	2	Q12959	1
+Disks large homologue 1, N-terminal PEST domain [IPR019590]	0.723714953271035	1.357652824347961	0.1745738727323487	1.0	0.3090056799722306	2	Q12959	1
+Cold-shock protein, DNA-binding [IPR002059]	0.8845106392115871	1.3049464587019106	0.1919110798987142	1.0	0.3315257989372364	4	P67809	1
+Cold shock domain [IPR011129]	0.8845106392115871	1.3049464587019106	0.1919110798987142	1.0	0.3315257989372364	4	P67809	1
+Thioredoxin-like fold [IPR012336]	0.7129088785046782	1.30386687254581	0.1922789770300381	1.0	0.3319566812311564	2	Q8NBF2	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.7928717499269802	1.2801689722341008	0.2004857156689192	1.0	0.3414960336196424	3	Q9BYT8,Q99797	2
+PABP, RNA recognition motif 2 [IPR045305]	0.7079439252336505	1.279172855500167	0.2008361923953714	1.0	0.3416776023629816	2	P11940	1
+Patatin-like phospholipase domain [IPR002641]	0.6959696261682304	1.2196923214724011	0.2225815335069985	1.0	0.3619695048674461	2	Q8IY17	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.695677570093464	1.2182432388203666	0.2231315528500457	1.0	0.362653486708717	2	Q9NR33	1
+PIN domain [IPR002716]	0.6953855140186974	1.21679424712017	0.2236825094054135	1.0	0.3631230687016611	2	Q9Y2L1	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7759918023078647	1.2050357451054226	0.2281895030089478	1.0	0.3672736906797524	3	P51114	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7759918023078647	1.2050357451054226	0.2281895030089478	1.0	0.3672736906797524	3	P51114	1
+Fxr1, tudor domain [IPR041560]	0.7759918023078647	1.2050357451054226	0.2281895030089478	1.0	0.3672736906797524	3	P51114	1
+Agenet-like domain [IPR008395]	0.7759918023078647	1.2050357451054226	0.2281895030089478	1.0	0.3672736906797524	3	P51114	1
+Translation initiation factor IF- 2, domain 3 [IPR023115]	0.6869158878504734	1.1748169409318805	0.2400679609871503	1.0	0.3798251985804603	2	O60841	1
+Vps16, C-terminal [IPR006925]	0.6822429906542122	1.1516979407153134	0.2494452187868518	1.0	0.3924455379229416	2	Q9H9C1	1
+PAP/25A-associated [IPR002058]	0.6810747663551467	1.1459233380588711	0.2518268737269475	1.0	0.3949461836797057	2	Q5TAX3	1
+TUTase nucleotidyltransferase domain [IPR045100]	0.6810747663551467	1.1459233380588711	0.2518268737269475	1.0	0.3949461836797057	2	Q5TAX3	1
+CTP synthase, N-terminal [IPR017456]	0.6693925233644926	1.0883078172289231	0.2764592406818869	1.0	0.4230965458063839	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.6693925233644926	1.0883078172289231	0.2764592406818869	1.0	0.4230965458063839	2	P17812	1
+F-BAR domain [IPR031160]	0.6685163551401938	1.0839972519494463	0.2783660172833098	1.0	0.4241335402000185	2	Q9UNF0	1
+FCH domain [IPR001060]	0.6685163551401938	1.0839972519494463	0.2783660172833098	1.0	0.4241335402000185	2	Q9UNF0	1
+ERAP1-like C-terminal domain [IPR024571]	0.8256061192080046	1.0681710698889466	0.2854433520825736	1.0	0.4319032964642833	4	P55786,Q6P179	2
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.7347356120362392	1.022771017009923	0.3064161245724901	1.0	0.4540338345066723	3	Q4G0X4,Q9NXV2	2
+Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]	0.6512850467289797	0.9995915162630638	0.3175082304494587	1.0	0.4657895611096248	2	Q13243	1
+Serpin domain [IPR023796]	0.7277242185217698	0.9920954178628772	0.3211509815548408	1.0	0.4694131717875138	3	P35237,P50454	2
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.7274320771253392	0.9908197294405358	0.3217736136687468	1.0	0.4700780320645613	3	Q96EY1,O60884	2
+Dynamin, GTPase domain [IPR001401]	0.7110210508479672	0.9195147661103166	0.3578263857624995	1.0	0.5068597334902637	3	P50570	1
+SUN domain [IPR012919]	0.7063342613413539	0.8992935291882334	0.368496333135631	1.0	0.5157476151079111	3	Q9UH99	1
+Disulphide isomerase [IPR005788]	0.8558900906167873	0.8841884299441013	0.3765945030376105	1.0	0.5244621259996942	5	Q8NBS9,P13667,Q15084,P07237	4
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.7776585531351542	0.8790431087877795	0.379377902496592	1.0	0.5265993105215439	4	P39687,Q15435	2
+NOPS [IPR012975]	0.7012310613020907	0.8773567556542311	0.3802928938605241	1.0	0.5267329157672707	3	Q8WXF1	1
+Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]	0.6235397196261767	0.8656346490956316	0.386690548107663	1.0	0.5313913270219087	2	Q96RL7	1
+Autophagy-related, C-terminal [IPR015412]	0.6235397196261767	0.8656346490956316	0.386690548107663	1.0	0.5313913270219087	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]	0.6235397196261767	0.8656346490956316	0.386690548107663	1.0	0.5313913270219087	2	Q96RL7	1
+VPS13, repeated coiled region [IPR031642]	0.6235397196261767	0.8656346490956316	0.386690548107663	1.0	0.5313913270219087	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]	0.6235397196261767	0.8656346490956316	0.386690548107663	1.0	0.5313913270219087	2	Q96RL7	1
+AMPK, C-terminal adenylate sensor domain [IPR032270]	0.6077686915887941	0.7909579495381556	0.4289685302781572	1.0	0.57100704125387	2	Q13131	1
+Ribosomal protein S7 domain [IPR023798]	0.6071845794392616	0.7882170596420711	0.4305697520785023	1.0	0.5726828605933157	2	Q9Y2R9	1
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.6066004672897287	0.785478083010751	0.4321733155724501	1.0	0.574345094993414	2	P52701	1
+PTB/PI domain [IPR006020]	0.6776357123019112	0.7771981333997027	0.4370418833246421	1.0	0.5778708467389372	3	Q9Y3P9	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6748466257668818	0.7655153478755041	0.4439647307942345	1.0	0.5815309899975125	3	Q9UL46,P61289	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6748466257668818	0.7655153478755041	0.4439647307942345	1.0	0.5815309899975125	3	Q9UL46,P61289	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.7440093512565733	0.7499849260400817	0.4532637834722199	1.0	0.5891576428105256	4	Q9Y5X3,O60749,Q13596	3
+Heat shock chaperonin-binding [IPR006636]	0.8114091966404247	0.728541916186021	0.4662819195429257	1.0	0.5971306848991216	5	P54725,Q9UMX0,Q9BSL1	3
+Exportin-2, central domain [IPR013713]	0.6625766871165693	0.7145738056281923	0.4748724354331743	1.0	0.6050898426938401	3	O15397,O95373	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7294272879843765	0.6953870618383506	0.4868127665449264	1.0	0.6144366539904883	4	P27544,Q96G23	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.8707482420950525	0.6896070772611143	0.4904413155367781	1.0	0.6173153495978945	7	Q32P28,Q6PK18,O60568,O15460,P13674	5
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.8707482420950525	0.6896070772611143	0.4904413155367781	1.0	0.6173153495978945	7	Q32P28,Q6PK18,O60568,O15460,P13674	5
+Complex 1 LYR protein domain [IPR008011]	0.5855724299065521	0.6882738029978513	0.4912803755147132	1.0	0.6173153495978945	2	Q9Y6M9	1
+eRF1 domain 2 [IPR005141]	0.5832359813084211	0.6776581805796629	0.4979884476547815	1.0	0.6226522223688968	2	P62495	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.5832359813084211	0.6776581805796629	0.4979884476547815	1.0	0.6226522223688968	2	P62495	1
+eRF1 domain 3 [IPR005142]	0.5832359813084211	0.6776581805796629	0.4979884476547815	1.0	0.6226522223688968	2	P62495	1
+BAG domain [IPR003103]	0.7186579809998013	0.655689328049241	0.5120240367790971	1.0	0.6331382837842146	4	O95429	1
+Ariadne domain [IPR045840]	0.5756425233644962	0.6434442771379995	0.5199358609301519	1.0	0.6392541826793706	2	Q9Y4X5	1
+ROCK, Rho binding domain [IPR015008]	0.5738901869158981	0.635613778051587	0.5250281869121727	1.0	0.6435384863201696	2	O75116	1
+Domain of unknown function DUF5600 [IPR040990]	0.5677570093458051	0.6084098979478326	0.5429156484176854	1.0	0.6591202976024066	2	Q9H4M9	1
+EH domain-containing protein, N-terminal [IPR031692]	0.5677570093458051	0.6084098979478326	0.5429156484176854	1.0	0.6591202976024066	2	Q9H4M9	1
+Intermediate filament, rod domain [IPR039008]	0.8358616450743598	0.5879099240244082	0.5565927549181535	1.0	0.6731000860080562	8	P08670,P07196,Q16352,P07197	4
+Myosin tail [IPR002928]	0.6295647093193116	0.5818762699133705	0.5606500255838687	1.0	0.6768381610021543	3	P35580,Q7Z406	2
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.8351104420436783	0.5798029229850251	0.5620475262258264	1.0	0.6782330613629481	7	Q8N8N7	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.561039719626179	0.5789960644114294	0.5625918287190457	1.0	0.6785976341243073	2	P34897	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8332341490462398	0.5687337872242352	0.5695368149317743	1.0	0.6860886308851383	6	Q8WUJ1	1
+GRAM domain [IPR004182]	0.692948807688136	0.56342259448935	0.5731471551821457	1.0	0.6886613759950138	4	Q66K14	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.6237218813906114	0.5591707199528048	0.5760452139307712	1.0	0.691846845021012	3	Q6BDS2,Q96RL7	2
+EF-hand, Ca insensitive [IPR014837]	0.6170026292725708	0.533391592056716	0.5937625365180608	1.0	0.7125150438216729	3	P12814,O43707	2
+Cyclic nucleotide-binding domain [IPR000595]	0.7458454308670529	0.5127577430230705	0.6081207922869298	1.0	0.7284969901615979	5	Q9Y4G8	1
+ERM family, FERM domain C-lobe [IPR041789]	0.6105755185509893	0.5090842604718344	0.6106931637790667	1.0	0.7312659166277542	3	P15311,P35241	2
+TATA-binding protein interacting (TIP20) [IPR013932]	0.5435163551401984	0.5043382040147821	0.6140237351329034	1.0	0.7349399854089685	2	O75155	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.6082383873794944	0.500334003795645	0.6168399147822905	1.0	0.7376513871144197	3	Q06203,P08243	2
+Nuclear transport factor 2, eukaryote [IPR018222]	0.6064010630720991	0.4934892297789404	0.6216669480257702	1.0	0.7418700120818603	3	Q9UN86	1
+Nuclear transport factor 2 domain [IPR002075]	0.6064010630720991	0.4934892297789404	0.6216669480257702	1.0	0.7418700120818603	3	Q9UN86	1
+MoaB/Mog domain [IPR001453]	0.5373831775701036	0.4789868646849627	0.6319479732263926	1.0	0.7522167463807783	2	Q8NFF5	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.7278573516515844	0.4575128587004902	0.6473024620005028	1.0	0.7675588229053782	5	Q96EY1,O60884,Q9UBS4,P25685	4
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7823278098360471	0.4510495705839331	0.6519538224177439	1.0	0.7727472971296608	12	O95302,Q9NWM8,Q96AY3,Q9Y680	4
+Leucine-rich repeat N-terminal domain [IPR000372]	0.5268691588785167	0.436565663716893	0.6624263686594434	1.0	0.783407732001565	2	O94813	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.5268691588785167	0.436565663716893	0.6624263686594434	1.0	0.783407732001565	2	O94813	1
+OCRE domain [IPR041591]	0.5886212916161373	0.4288990129385232	0.6679967185751254	1.0	0.7877638070065243	3	P98175	1
+Protein kinase, C-terminal [IPR017892]	0.7792704231796737	0.4231751949619806	0.6721674431689169	1.0	0.789806762305443	8	P51812,Q15418	2
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.7092579397810388	0.4026358209319782	0.6872161538074824	1.0	0.8046718190424428	5	P48735,O75874	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7591116573410719	0.3625330570393797	0.7169537252384439	1.0	0.8315001399495529	6	P55786,Q6P179	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7591116573410719	0.3625330570393797	0.7169537252384439	1.0	0.8315001399495529	6	P55786,Q6P179	2
+Myotubularin-like phosphatase domain [IPR010569]	0.5685071574642236	0.3597927060704562	0.7190021581446249	1.0	0.8335308428304671	3	Q13614,O95248	2
+LEM domain [IPR003887]	0.756709029792399	0.3563928144362931	0.7215464098307665	1.0	0.8352388202040762	6	Q86XL3,P42167,P50402	3
+Armadillo repeat-containing domain [IPR006911]	0.5040887850467419	0.3496551576380308	0.7265975107970963	1.0	0.8399035582728812	2	Q8N2F6	1
+FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]	0.5005841121495457	0.3369487342802373	0.7361555465593601	1.0	0.8495501818201512	2	Q9Y4F1	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.4997079439252423	0.3338015346650313	0.7385293252911749	1.0	0.8515881355826633	2	P13861	1
+Arrestin-like, N-terminal [IPR011021]	0.4985397196261814	0.329623779760648	0.7416842522812177	1.0	0.8541693037928482	2	P49407	1
+Arrestin C-terminal-like domain [IPR011022]	0.4985397196261814	0.329623779760648	0.7416842522812177	1.0	0.8541693037928482	2	P49407	1
+AGC-kinase, C-terminal [IPR000961]	0.7382946895217607	0.3286595401854154	0.7424130391166295	1.0	0.8541693037928482	12	P51812,Q15418	2
+FAD dependent oxidoreductase [IPR006076]	0.6197691094864801	0.3267126492878703	0.7438852320884082	1.0	0.8549493110384412	4	Q8NCN5	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.4962032710280494	0.3213323113618208	0.7479585727643594	1.0	0.8578714371206447	2	P42695	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.4944509345794525	0.3151703447263418	0.7526323204737921	1.0	0.8618209080374195	2	P49841	1
+GYF domain [IPR003169]	0.4935747663551496	0.3121077456033067	0.7549586402221831	1.0	0.8640201482710922	2	O95400	1
+Putative WW-binding domain and destruction box [IPR033461]	0.4926985981308542	0.3090574867090099	0.7572777977536576	1.0	0.8660785262472444	2	Q9ULX3	1
+Nucleotidyl transferase domain [IPR005835]	0.5450301688386571	0.285208577490429	0.775484349273468	1.0	0.8818616666656888	3	Q9NR50	1
+RasGAP protein, C-terminal [IPR000593]	0.5444757425550681	0.2835331363142443	0.7767681842410501	1.0	0.8829632666301916	3	Q13576	1
+EF-hand domain [IPR002048]	0.6233693444329756	0.2823311337117582	0.7776896149455428	1.0	0.8836521902179282	48	O95302,O43852,P41208,Q9NWM8,Q14257,Q96AY3,P0DP25,Q02818,Q9Y680,P80303,Q15293	11
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.4813084112149668	0.270555084538721	0.7867332450333193	1.0	0.8899582368120148	2	P46926	1
+Thioredoxin domain [IPR013766]	0.6917242188788002	0.2673297067541466	0.7892153161145159	1.0	0.892405696429731	25	P13667,Q9P2K2,Q9BS26,Q96JJ7,Q8NBS9,Q9Y2G8,P30101,Q15084,O95881,P07237,Q13162,O43396,Q8IXB1	13
+Tim44-like domain [IPR007379]	0.4737149532710417	0.2461162100524205	0.8055922751487161	1.0	0.9087236533682376	2	O43615	1
+HDGF-related, PWWP domain [IPR035496]	0.5226922148444718	0.2210790662455216	0.8250308697060718	1.0	0.9258055654450992	3	P51858	1
+L27 domain, C-terminal [IPR014775]	0.633978224032953	0.209157802072096	0.8343250528896489	1.0	0.9336177309092636	5	Q14168,O14936,Q8N3R9	3
+Pentacotripeptide-repeat region of PRORP [IPR033443]	0.4591121495327185	0.2020282050402299	0.8398946743596287	1.0	0.9379772329835312	2	O75127	1
+L27 domain [IPR004172]	0.6878640156402493	0.1993709616519756	0.8419725737373729	1.0	0.9392712200205048	7	Q14168,O14936,O75970,Q12959	4
+SET domain [IPR001214]	0.6831619859451036	0.1928616133085044	0.8470673487183773	1.0	0.9433556085488446	10	Q9H7B4	1
+MCM OB domain [IPR033762]	0.6824052932431302	0.1877666714834941	0.851059563328624	1.0	0.9459218153299502	6	Q14566,P25205	2
+MCM, AAA-lid domain [IPR041562]	0.6824052932431302	0.1877666714834941	0.851059563328624	1.0	0.9459218153299502	6	Q14566,P25205	2
+MCM domain [IPR001208]	0.6824052932431302	0.1877666714834941	0.851059563328624	1.0	0.9459218153299502	6	Q14566,P25205	2
+MCM N-terminal domain [IPR027925]	0.6824052932431302	0.1877666714834941	0.851059563328624	1.0	0.9459218153299502	6	Q14566,P25205	2
+Rab-GTPase-TBC domain [IPR000195]	0.6794173476795021	0.1824166278384475	0.8552557776007212	1.0	0.9502088377625776	7	Q0IIM8,O60343,Q9Y3P9,Q8TC07,Q66K14	5
+Helicase/UvrB, N-terminal [IPR006935]	0.5076371246278446	0.1819517705184081	0.8556205755429314	1.0	0.9502373573806158	3	Q9UPY3	1
+FKBP3, basic tilted helix bundle domain [IPR041200]	0.4491822429906619	0.1743243862182154	0.861610535226478	1.0	0.9546195016625508	2	Q00688	1
+Guanylate kinase-like domain [IPR008144]	0.6724840568401262	0.1709568664554468	0.8642576817968219	1.0	0.9567957425502548	10	Q14168,O14936,Q07157,Q00013,Q12959,Q8N3R9,Q9UDY2	7
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.6724840568401262	0.1709568664554468	0.8642576817968219	1.0	0.9567957425502548	10	Q14168,O14936,Q07157,Q00013,Q12959,Q8N3R9,Q9UDY2	7
+Syntaxin, N-terminal domain [IPR006011]	0.5013146362839812	0.1665490781643763	0.8677248636585868	1.0	0.9598865364886152	3	Q12846,Q86Y82	2
+DEUBAD  domain [IPR044867]	0.4462616822430008	0.1665365927077474	0.8677346884103008	1.0	0.9598865364886152	2	Q16186	1
+IMP dehydrogenase/GMP reductase [IPR001093]	0.4992696465089217	0.1616998672002079	0.871542209123586	1.0	0.9624474615542952	3	P12268,Q9P2T1	2
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.4972246567338746	0.1569159821911239	0.8753110639296817	1.0	0.9659793623989634	3	P00390,P09622	2
+tRNA/rRNA methyltransferase, SpoU type [IPR001537]	0.4401285046729121	0.1507231773054164	0.8801940892550277	1.0	0.9698402823800976	2	Q9HC36	1
+DnaJ domain [IPR001623]	0.6463985293727803	0.1293195223334086	0.8971048245510969	1.0	0.9849873504671526	18	O75937,P25685,Q99543,P31689,Q96EY1,Q9UBS4,Q13217,Q9Y2G8,Q8WXX5,O60884,O14976,Q96KC8,Q8IXB1,Q9UGP8	14
+Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]	0.4767747589833669	0.1127111629431794	0.9102595509003906	1.0	0.9920448314363648	3	Q9BTE6,Q5JTZ9	2
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.4211448598130949	0.1064835741653111	0.9151986872260344	1.0	0.995953031944553	2	Q15008	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.6346759496638495	0.1033694374884794	0.9176697675309832	1.0	0.9970184911290482	7	O14818,P25787,P25788	3
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.6218523045544723	0.0841345538070778	0.9329494520625612	1.0	1.0	7	Q16763,Q9NR09,P49427	3
+Amino acid permease/ SLC12A domain [IPR004841]	0.4091705607476792	0.0822578739795129	0.9344416525429552	1.0	1.0	2	P55011	1
+SLC12A transporter, C-terminal [IPR018491]	0.4091705607476792	0.0822578739795129	0.9344416525429552	1.0	1.0	2	P55011	1
+Methylthiotransferase, N-terminal [IPR013848]	0.4085864485981398	0.0811485518946982	0.935323814145666	1.0	1.0	2	Q96SZ6	1
+TRAM domain [IPR002792]	0.4085864485981398	0.0811485518946982	0.935323814145666	1.0	1.0	2	Q96SZ6	1
+Ras GTPase-activating domain [IPR001936]	0.564521448223525	0.080390820843924	0.9359264271825594	1.0	1.0	5	Q14C86,Q13576	2
+Ribosomal protein S5, N-terminal [IPR013810]	0.4077102803738429	0.0794971234580714	0.9366372195215742	1.0	1.0	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.4077102803738429	0.0794971234580714	0.9366372195215742	1.0	1.0	2	P82675	1
+E3 ligase, CCCH-type zinc finger [IPR041367]	0.457437460992227	0.0770353178975408	0.9385954488168796	1.0	1.0	3	Q86VM9	1
+GOLD domain [IPR009038]	0.6149824593825701	0.0757050495225528	0.9396537585871892	1.0	1.0	6	Q9Y3A6,Q9BVK6	2
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.3986565420560852	0.063308478270291	0.9495208646249896	1.0	1.0	2	Q14240	1
+Zinc finger, RanBP2-type [IPR001876]	0.6060135230169792	0.0599442987188212	0.9521999980323744	1.0	1.0	9	Q92804,Q01844,P35637,P98175	4
+BZW1/2, W2 domain [IPR043510]	0.3957359813084183	0.0584237342838122	0.9534111098341844	1.0	1.0	2	Q9Y6E2	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.440607399254547	0.0507709557357323	0.9595080349832936	1.0	1.0	3	Q8N4A0	1
+Pre-PUA domain [IPR041366]	0.3881425233644964	0.0464790930983115	0.9629283973652392	1.0	1.0	2	P41214	1
+IBR domain [IPR002867]	0.4312007011393576	0.0379712858741892	0.9697105760642156	1.0	1.0	3	Q9Y4X5,O95376	2
+TRIAD supradomain [IPR044066]	0.4312007011393576	0.0379712858741892	0.9697105760642156	1.0	1.0	3	Q9Y4X5,O95376	2
+EH domain [IPR000261]	0.583333972101022	0.0374262220534299	0.9701451651381894	1.0	1.0	6	Q96D71	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.5865063971559402	0.0340238048497108	0.9728581681630288	1.0	1.0	10	P49748	1
+RAP domain [IPR013584]	0.3709112149532841	0.0232763488414149	0.9814298374925324	1.0	1.0	2	Q969Z0	1
+FAST kinase leucine-rich [IPR010622]	0.3709112149532841	0.0232763488414149	0.9814298374925324	1.0	1.0	2	Q969Z0	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.3709112149532841	0.0232763488414149	0.9814298374925324	1.0	1.0	2	Q969Z0	1
+BAT2, N-terminal [IPR009738]	0.4125036517674553	0.0163250190428174	0.9869750978897888	1.0	1.0	3	P48634,Q5JSZ5	2
+UBX domain [IPR001012]	0.5024607906053702	0.0087767968968232	0.9929972191693976	1.0	1.0	5	O94888	1
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.5599845810983819	0.0080225935429303	0.9935989651384812	1.0	1.0	9	P14625,O14874	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:8255cb3ed6fdf46095f0819dc0faf68a733ef1ff05492d36db66c360df36c2f4
+size 551029