Upload folder using huggingface_hub

interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a7038479f737908f5900abe2d5f0bc7fbce3f079cd45816fade7d575d70b0d85
+size 80553

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3215,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.6315789473684212
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C133/C133_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein-tyrosine phosphatase, active site [IPR016130]	0.6425699935813167	1.4773509636591289	0.1395815834135985	0.9998101315695264	0.1940524452335393	6	Q9H3S7,Q8NCE2	2
+Glycosyl hydrolases family 31, active site [IPR030458]	0.4550264550264712	0.635135477710378	0.5253400602219247	1.0	0.5680560311324061	2	Q14697	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.4563866130852217	0.6307676629206516	0.5281924500003075	1.0	0.5680560311324061	3	Q16881	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.4410109850658378	0.5448408838568536	0.5858629573319178	1.0	0.6184108994059133	5	P49427	1
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.3244084682440822	0.1570821887669415	0.8751800746170197	1.0	0.8751800746170197	3	Q8TBC4,Q9UBT2	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAPN1", "CAPN2", "CASP7", "CASP8", "CDC34", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "JAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAPK1", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME3", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRC", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["CDC34", "GANAB", "MTMR14", "PTPN23", "TXNRD1", "UBA2", "UBA3"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:684f597f63542e39702743296f120b0412bd3b8dd648eabbf5e149bbc7aa92f5
+size 76838

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M16, zinc-binding site [IPR001431]	3	5	2.0840021746628894	0.0371599694545108	1.730582524271845	5.0	0.6776547957610433	0.4740055886775391	1.2118895823030245	0.0	0.8079860258854747	0.314626832259423	1.0	1.0	1.0	1.0	0.0214122317398669

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3215,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.645161290322581
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C133/C133_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.7715802906119656	2.0840021746628894	0.0371599694545108	0.6908435743518342	0.0822827895064168	5	P22695,O43847,Q10713	3
+Beta tubulin, autoregulation binding site [IPR013838]	0.4478355652444745	0.583707736671973	0.5594169611892787	0.9999999999907772	0.6193544927452729	4	Q9BUF5,P07437,P68371	3
+IQ motif, EF-hand binding site [IPR000048]	0.4081446103226306	0.3501959902469267	0.7261916157979194	1.0	0.7465824969797612	12	Q86VI3,P35580,Q7Z406,Q92614	4
+EF-Hand 1, calcium-binding site [IPR018247]	0.4283576365588123	0.3231488753349831	0.7465824969797612	1.0	0.7465824969797612	35	Q9NWM8,P80303,O75340,Q9UBC2,Q9Y680,Q02818,Q14257,Q96AY3	8

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APEX2", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK1", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "JAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["EPS15L1", "FKBP10", "FKBP14", "FKBP7", "IQGAP3", "MYH10", "MYH14", "MYO18A", "NRDC", "NUCB1", "NUCB2", "PDCD6", "PMPCA", "RCN2", "TUBB", "TUBB4B", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Ubiquitin specific protease, conserved site [IPR018200]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b94e366ad7a05c81e4ddef0d77987a87cfcb7cd4b04da279d2455f83095f61c5
+size 110487

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	4	8	1.974780165512748	0.0482931008624967	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	1.0	0.0039921150854813	6.393058955734768e-05	5.489393781591606e-05

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3215,
+    "annotations_size": 278,
+    "title": "Average number of proteins per term",
+    "value": 2.723021582733813
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C133/C133_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Sterol reductase, conserved site [IPR018083]	0.970432617491439	2.946323860464943	0.0032157551013187	0.591564151010671	0.062770813370911	2	Q9UBM7	1
+Haem oxygenase conserved site [IPR018207]	0.9567382508558978	2.8907083776221287	0.0038437461516032	0.657204200985807	0.062770813370911	2	P09601	1
+Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]	0.9000069355777617	2.652817955482817	0.007982290879769	0.8922542439744493	0.062770813370911	3	Q9H8V3	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7506955412564198	1.9747801655127477	0.0482931008624967	0.9999989434391876	0.1254717947642438	8	P49721,P28072,P28074,P28070	4
+Actin, conserved site [IPR004001]	0.6987239340180547	1.7691168740221606	0.0768743725008209	0.9999999997799583	0.173748581749823	2	O96019	1
+DnaJ domain, conserved site [IPR018253]	0.6719520249349622	1.5889301451245637	0.1120761645090762	0.9999999999999956	0.2155135076194226	11	Q99543,Q9Y2G8,Q9UBS4	3
+Profilin conserved site [IPR027310]	0.6470588235294022	1.528691960759123	0.1263408262058667	1.0	0.2326009912929202	2	P07737	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.6246498599439831	1.4232843142682814	0.1546537522320581	1.0	0.2653934760525441	2	P06737	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.5847795006545126	1.216962434658638	0.2236185088439066	1.0	0.3320617072813701	4	P21359	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.5798319327731083	1.2113685627800814	0.2257541822884134	1.0	0.3320617072813701	2	P09884	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.5610105530571219	1.07816270265326	0.2809611533497929	1.0	0.3832597991948407	7	O43752,Q9P2W9,Q13190	3
+FERM conserved site [IPR019747]	0.5614626568224228	1.0645631112853526	0.2870736804785063	1.0	0.3865571629775355	9	O94887	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.5347027699968909	0.9984012789474832	0.3180848137005669	1.0	0.4147063924707401	2	P14174	1
+Fumarate lyase, conserved site [IPR020557]	0.5337690631808344	0.9940213668418824	0.3202124652198852	1.0	0.4147063924707401	2	P30566	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.5270722358845625	0.95278750872455	0.3406977445067176	1.0	0.4190883759861393	3	Q08426	1
+Intermediate filament protein, conserved site [IPR018039]	0.5344696109738427	0.9428465973499632	0.3457593734136506	1.0	0.4234409947532813	8	P07196,P02545,P48681,P08670	4
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.470698171251844	2	Q9H9Y6	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.4830376595082623	0.7596574180257955	0.4474593881291713	1.0	0.5135298405143384	2	P04439	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.4796140678493676	0.7441982538438681	0.4567565442772925	1.0	0.5204029479880627	2	P50570	1
+DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]	0.4886372446122168	0.6878818816020175	0.4915271671464283	1.0	0.5554656604337685	13	Q92620,Q14562	2
+Hexapeptide transferase, conserved site [IPR018357]	0.4631185807656449	0.6706135682402867	0.5024667366295748	1.0	0.5655293634940153	2	Q96IJ6	1
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.4550264550264712	0.635135477710378	0.5253400602219247	1.0	0.588889261055222	2	Q14697	1
+Heavy-metal-associated, conserved site [IPR017969]	0.4491129785247436	0.6095033017227702	0.5421908849249601	1.0	0.6053376144945338	2	P35670	1
+Clathrin adaptor complex, small chain [IPR000804]	0.4362033669217097	0.5442505070568833	0.5862691000446338	1.0	0.6442008292980561	3	P61923	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4249688667496865	0.4976620999181637	0.6187222255938121	1.0	0.6745285439807049	3	P08238,P14625	2
+Zinc finger, RING-type, conserved site [IPR017907]	0.3627696136549535	0.1722506356220002	0.8632404912627762	1.0	0.9090183961024688	15	Q99496,P38398,P19474	3
+Serpin, conserved site [IPR023795]	0.3174603174603186	0.1480545707416596	0.8822997015248342	1.0	0.922102695578586	2	P35237	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.3225066947500515	0.1291706423143635	0.897222625607748	1.0	0.934186853629041	6	O00443,Q9UBF8,P42345	3
+Ubiquitin specific protease, conserved site [IPR018200]	0.3384364161344082	0.1117179979742901	0.9110470083466932	1.0	0.9438579384988866	14	Q86UV5,P51784,Q96K76,Q70CQ2,Q9UPU5	5
+Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]	0.3325701970953933	0.0973466332085537	0.9224511238816048	1.0	0.9438579384988866	14	Q5T160	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.2964808470881372	0.0879054109553763	0.9299518559354788	1.0	0.9469839412090224	4	Q9UBQ7,Q13363,O43175	3
+Bromodomain, conserved site [IPR018359]	0.3064024886887956	0.0604622117930924	0.9517875113838083	1.0	0.9621706478716318	11	O95696,Q12830	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "ATR", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN2", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MNAT1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSD3", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACTL6A", "ADSL", "ATP7B", "BPTF", "BRCA1", "BRD1", "COPZ1", "CTBP1", "DHCR7", "DHX38", "DHX8", "DNAJB11", "DNAJC16", "DNAJC2", "DNM2", "ECT2", "EHHADH", "FARP2", "GANAB", "GMPPA", "GRHPR", "HLA-A", "HMOX1", "HSP90AB1", "HSP90B1", "LMNA", "MIF", "MTOR", "NEFL", "NES", "NF1", "PFN1", "PHGDH", "PI4KB", "PIK3C2A", "POLA1", "POLR1B", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PYGL", "RARS2", "RNF2", "SERPINB6", "STX18", "STX5", "STX6", "TRIM21", "USP11", "USP24", "USP34", "USP47", "USP48", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "SH2 domain [IPR000980]", "2": "RNA recognition motif domain, eukaryote [IPR003954]", "3": "Ubiquitin-associated domain [IPR015940]", "4": "Zinc finger, CCHC-type [IPR001878]", "5": "DnaJ domain [IPR001623]", "6": "Zinc finger, RING-type [IPR001841]", "7": "TOG domain [IPR034085]", "8": "EF-hand domain [IPR002048]", "9": "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "10": "Helicase, C-terminal [IPR001650]", "11": "Double-stranded RNA-binding domain [IPR014720]", "12": "PDZ domain [IPR001478]", "13": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "14": "SNF2, N-terminal [IPR000330]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:ae438a91ed24b77ae517a83a8fc6190982d91f12983b3cebc49fbbe5664bb7d0
+size 552099

interpro_domain/df_merge.tsv

@@ -0,0 +1,9 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	7	11	2.6760214886356626	0.0074501868185639	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.005091041223929	2.8841975049086312e-05	5.5913743904608274e-06	7.014604493490859e-09	3.0771941242748986e-08
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	5	2.451397382765663	0.0142302755291865	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	1.0	0.075113296023457	0.0007272762906085	0.0053334351931861
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	5	2.451397382765663	0.0142302755291865	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	1.0	0.075113296023457	0.0007272762906085	0.0053334351931861
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	6	2.350870937875117	0.0187295289916242	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	1.0	0.0561990347849709	0.0057815105752346	0.0331187861076589	0.0020033682110678
+Chaperone DnaJ, C-terminal [IPR002939]	0	5	2.287978270637021	0.022138786566729	2.220873786407767	4.723300970873787	-0.0582402111442515	0.6027858517824302	1.283673132937458	0.8250570893451368	0.7868857680351762	0.2924953883323574	1.0	0.0378187125466048	0.075113296023457	0.1788587842302525	0.3290745839784397
+Heat shock chaperonin-binding [IPR006636]	1	5	2.2440050526348925	0.0248320762542957	1.9975728155339805	4.283980582524272	0.4073375669327513	0.504919451488752	1.1374020525583366	1.1188741218715514	0.9480073173795736	0.3222446616186543	1.0	1.0	0.075113296023457	0.1788587842302525	0.0544194668097373
+Dbl homology (DH) domain [IPR000219]	3	6	2.235647009497934	0.0253749026841569	2.1650485436893203	4.970873786407767	-0.2603834385846391	0.4983949433662193	1.675622402135014	2.7000766284689237	1.1060587808067857	0.3262483259439779	1.0	0.2295798469686227	0.0965403494275516	0.1435696883620607	0.2675058784158126
+FERM adjacent (FA) [IPR014847]	1	5	2.025648729362594	0.0428007941678607	2.441747572815534	4.080097087378641	-0.5052776638489634	0.5203220766309672	1.3380194225479194	1.1452273231293435	0.8344328146338481	0.307425526613345	1.0	1.0	0.0841007109914387	0.1988473022417859	0.0677640175569944

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3215,
+    "annotations_size": 2675,
+    "title": "Average number of proteins per term",
+    "value": 2.1861682242990654
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C133/C133_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,266 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Phospholipase D/Transphosphatidylase [IPR001736]	0.990974167444755	3.0290383891073813	0.002453335061922	0.9985992321063828	0.0580459145210401	2	Q8IV08	1
+EXPERA domain [IPR033118]	0.972922502334266	2.956394961243097	0.0031125822923889	0.99976102282409	0.0580459145210401	2	Q15125	1
+Amine oxidase [IPR002937]	0.9644802707922088	2.9199677679225404	0.0035006759040259	0.9999156669822584	0.0580459145210401	3	P50336	1
+DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]	0.9533146591970088	2.876744860110156	0.0040180032508543	0.9999789752402674	0.0580459145210401	2	Q06609	1
+ERAP1-like C-terminal domain [IPR024571]	0.9389788293897882	2.8153351892443257	0.0048726382639765	0.999997884388418	0.0580459145210401	3	Q9NZ08,P55786	2
+SWIRM domain [IPR007526]	0.9300026847867068	2.775808551920146	0.0055064622386733	0.999999615180132	0.0580459145210401	4	Q8NB78	1
+NSD, Cys-His rich domain [IPR041306]	0.9203236850295676	2.740949490490656	0.0061261924195037	0.9999999273757804	0.0580459145210401	2	O96028	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.908198308349816	2.6760214886356626	0.0074501868185639	0.9999999979467848	0.0586363398837057	11	P26885,P62942,Q96AY3,Q02790,Q9Y680,Q13451,Q9NWM8	7
+IKBKB, scaffold dimerization domain [IPR041185]	0.8854652972300046	2.594992523884974	0.0094592976521936	0.999999999990912	0.0586363398837057	2	O15111	1
+I-kappa-kinase-beta NEMO binding domain [IPR022007]	0.8854652972300046	2.594992523884974	0.0094592976521936	0.999999999990912	0.0586363398837057	2	O15111	1
+GAT domain [IPR004152]	0.8832866479925214	2.5857846481492226	0.0097157612565299	0.999999999995454	0.0586363398837057	2	Q9UJY5	1
+N-terminal extension of GAT domain [IPR041198]	0.8832866479925214	2.5857846481492226	0.0097157612565299	0.999999999995454	0.0586363398837057	2	Q9UJY5	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.8605664488017457	2.4891545330592044	0.0128047295329198	0.9999999999999988	0.0650499076437923	2	Q15118	1
+Histidine kinase domain [IPR005467]	0.8605664488017457	2.4891545330592044	0.0128047295329198	0.9999999999999988	0.0650499076437923	2	Q15118	1
+Molybdenum cofactor sulfurase, C-terminal [IPR005302]	0.8581322892844128	2.4745992603400677	0.0133385749526389	0.9999999999999998	0.0657044238202951	3	Q5VT66	1
+MOSC, N-terminal beta barrel [IPR005303]	0.8581322892844128	2.4745992603400677	0.0133385749526389	0.9999999999999998	0.0657044238202951	3	Q5VT66	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8543976037586628	2.451397382765663	0.0142302755291865	1.0	0.0674928848237127	5	Q9NZ08,P55786	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8543976037586628	2.451397382765663	0.0142302755291865	1.0	0.0674928848237127	5	Q9NZ08,P55786	2
+GINS subunit, domain A [IPR021151]	0.8470448623245379	2.426779384638123	0.0152335161190597	1.0	0.0682543035901666	3	Q9BRX5	1
+KHDRBS, Qua1 domain [IPR032571]	0.8450046685340796	2.422329638478191	0.0154213546495092	1.0	0.0682543035901666	2	O75525	1
+Sam68, tyrosine-rich domain [IPR032335]	0.8450046685340796	2.422329638478191	0.0154213546495092	1.0	0.0682543035901666	2	O75525	1
+DOCKER domain [IPR027357]	0.8443821973233769	2.419645790584315	0.015535631746498	1.0	0.0682543035901666	2	Q96N67	1
+C2 DOCK-type domain [IPR027007]	0.8443821973233769	2.419645790584315	0.015535631746498	1.0	0.0682543035901666	2	Q96N67	1
+Acyltransferase, C-terminal domain [IPR032098]	0.8428260192965923	2.412932515818389	0.01582474926698	1.0	0.0685825058792794	2	Q9NUQ2	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.8350451291627778	2.3792878015064174	0.0173461269113066	1.0	0.0697763892353187	2	P49840	1
+MRH domain [IPR044865]	0.8348767245523802	2.373992546005294	0.0175969057250764	1.0	0.0698823114798326	3	P20645	1
+Domain of unknown function DUF3517 [IPR021905]	0.8301351282701621	2.353336219266265	0.0186058022536848	1.0	0.0718189336632133	3	Q70CQ2	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8321602260940122	2.350870937875117	0.0187295289916242	1.0	0.0719061504115729	6	Q9UMX5,O43169,Q8WUJ1	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8216619981325892	2.3211134498531876	0.0202807216755525	1.0	0.0744182859836803	2	P98179	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.8188608776843977	2.3088885599912015	0.0209497659717945	1.0	0.0759962573872229	2	Q7L576	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.8172666458676863	2.2970309080708615	0.0216170066123886	1.0	0.0772035950442451	3	P39687	1
+BAT2, N-terminal [IPR009738]	0.8160495035265489	2.2916868565106205	0.0219237193938646	1.0	0.0777983135457038	3	Q9Y520	1
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.8145527191659838	2.285110611407236	0.0223063427524841	1.0	0.0777983135457038	3	Q99956	1
+Dual specificity protein phosphatase domain [IPR020422]	0.8145527191659838	2.285110611407236	0.0223063427524841	1.0	0.0777983135457038	3	Q99956	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.8118870231394137	2.2733866930589604	0.023002887334653	1.0	0.0777983135457038	3	Q16134	1
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.8104876186073582	2.2672258833679697	0.0233764304326071	1.0	0.0781649392590302	3	Q9UJY5	1
+Heat shock chaperonin-binding [IPR006636]	0.807238188817059	2.2440050526348925	0.0248320762542957	1.0	0.0808460447699117	5	P54725	1
+Dbl homology (DH) domain [IPR000219]	0.8062216189230612	2.235647009497934	0.0253749026841569	1.0	0.0818321917928517	6	O94887,Q14155,Q9H8V3	3
+Zinc finger, CHHC-type [IPR012996]	0.8010585305105846	2.225604933112699	0.0260406554795147	1.0	0.0824363945653276	3	P55795,P52597	2
+Legume-like lectin [IPR005052]	0.7989417989417806	2.221469394712108	0.0263191854041773	1.0	0.0829909875763923	2	P49257	1
+Cyclin, C-terminal domain [IPR004367]	0.788671023965135	2.1760618203616953	0.0295506382870733	1.0	0.0883296782075689	2	O95067	1
+Cyclin, N-terminal [IPR006671]	0.788671023965135	2.1760618203616953	0.0295506382870733	1.0	0.0883296782075689	2	O95067	1
+SPRY-associated [IPR006574]	0.7854490877728163	2.1512284884345205	0.0314581694861202	1.0	0.09058191967209	4	P19474,O15344	2
+Butyrophylin-like, SPRY domain [IPR003879]	0.7854490877728163	2.1512284884345205	0.0314581694861202	1.0	0.09058191967209	4	P19474,O15344	2
+Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]	0.7780890133831173	2.1290436743715517	0.0332506471684785	1.0	0.093901224423171	2	Q8TEU7	1
+Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]	0.7780890133831173	2.1290436743715517	0.0332506471684785	1.0	0.093901224423171	2	Q8TEU7	1
+SAB domain [IPR007477]	0.7736194237877534	2.103404704005576	0.0354304076054448	1.0	0.0983880104631156	3	Q9Y2J2	1
+Band 4.1, C-terminal [IPR008379]	0.7736194237877534	2.103404704005576	0.0354304076054448	1.0	0.0983880104631156	3	Q9Y2J2	1
+Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]	0.7715530656707111	2.0998849341548502	0.0357389643679313	1.0	0.0983880104631156	2	P49588	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.7715530656707111	2.0998849341548502	0.0357389643679313	1.0	0.0983880104631156	2	P49588	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.7603485838779978	2.04969056013406	0.0403946367818948	1.0	0.1042002443505965	2	Q9UBF8	1
+FERM adjacent (FA) [IPR014847]	0.7587229951100907	2.025648729362594	0.0428007941678607	1.0	0.1082105835898997	5	O94887	1
+Ion transporter-like, CBS domain [IPR044751]	0.7519452225334623	2.011874150926369	0.0442332048768165	1.0	0.1103767006021309	2	Q6P4Q7	1
+CNNM, transmembrane domain [IPR002550]	0.7519452225334623	2.011874150926369	0.0442332048768165	1.0	0.1103767006021309	2	Q6P4Q7	1
+ARHGEF1-like, PH domain [IPR041020]	0.7513227513227474	2.0090671703504026	0.0445300107097592	1.0	0.1107042552496338	2	Q92888	1
+Complex 1 LYR protein domain [IPR008011]	0.7416744475568068	1.9654582764685984	0.0493612202312574	1.0	0.1169541754815001	2	Q9Y6M9	1
+Staufen, C-terminal [IPR032478]	0.7300747198007462	1.9062558369202385	0.0566170210166083	1.0	0.1273991329428646	3	O75569,Q9NUL3	2
+CRK, N-terminal SH3 domain [IPR035457]	0.7254901960784103	1.8918899320772804	0.0585056474876553	1.0	0.1294479793461355	2	P46108	1
+CRK, C-terminal SH3 domain [IPR035458]	0.7254901960784103	1.8918899320772804	0.0585056474876553	1.0	0.1294479793461355	2	P46108	1
+LIS1 homology motif [IPR006594]	0.73308022101783	1.884686751011528	0.0594721421594162	1.0	0.1305257337295882	10	O95684,Q7Z3E5	2
+Extended PHD (ePHD) domain [IPR034732]	0.7253089683604901	1.8844476573428337	0.0595044486214852	1.0	0.1305257337295882	3	O95696	1
+Myosin tail [IPR002928]	0.7250077857365127	1.876861835176164	0.060537032822681	1.0	0.1316080614751143	4	P35580,Q7Z406,Q92614	3
+Sirtuin family, catalytic core domain [IPR026590]	0.7186430127606398	1.8606108970934925	0.0627991448507345	1.0	0.1351469931421681	2	Q96EB6	1
+Kinesin-like KIF1-type [IPR022140]	0.715269044939579	1.8383617330688873	0.0660091199951111	1.0	0.1396949335339575	3	O60333	1
+Glycosyl transferase CAP10 domain [IPR006598]	0.7127295362589497	1.8335253243449612	0.0667244860400622	1.0	0.1409857821146654	2	Q7Z4H8	1
+MIRO domain [IPR020860]	0.7117958294428715	1.8292426477490065	0.0673632661377841	1.0	0.1412098764663823	2	Q8IXI2	1
+EF hand associated, type-2 [IPR013567]	0.7117958294428715	1.8292426477490065	0.0673632661377841	1.0	0.1412098764663823	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.7117958294428715	1.8292426477490065	0.0673632661377841	1.0	0.1412098764663823	2	Q8IXI2	1
+Stromalin conservative domain [IPR020839]	0.7105508870214807	1.823529885237083	0.0682231750041881	1.0	0.1416902120622697	2	Q8WVM7	1
+STAG [IPR013721]	0.7105508870214807	1.823529885237083	0.0682231750041881	1.0	0.1416902120622697	2	Q8WVM7	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.7077497665732958	1.8106656675133264	0.0701926204273268	1.0	0.1438814250138692	2	P51784	1
+FKBP3, basic tilted helix bundle domain [IPR041200]	0.7046374105197659	1.7963551755112106	0.0724380479204278	1.0	0.1473549644008703	2	Q00688	1
+AWS domain [IPR006560]	0.7007446167426578	1.7713573696730869	0.0765012929190021	1.0	0.1527986264404788	3	O96028	1
+CTLH, C-terminal LisH motif [IPR006595]	0.7013228601402804	1.7673771079307434	0.077165094115287	1.0	0.1534622982921611	4	O94967,Q96S59	2
+Helicase/UvrB, N-terminal [IPR006935]	0.6947111358450175	1.7434117897168973	0.0812617103730053	1.0	0.1584064194822284	3	P19447	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6928104575163413	1.74181641359245	0.0815405736769747	1.0	0.1586334796988418	2	Q96AE4	1
+Death domain [IPR000488]	0.693648816936487	1.7384847934905088	0.0821254272454474	1.0	0.1594466130934175	3	Q13546,Q12955	2
+Ras-associating (RA) domain [IPR000159]	0.6951269158379364	1.732160498466403	0.0832449900166683	1.0	0.1614795854202956	5	Q96L92,Q8TEU7	2
+Formin, GTPase-binding domain [IPR010473]	0.6896576192294276	1.719956397589623	0.0854403676625783	1.0	0.1631188961255428	3	O60879	1
+Formin, FH3 domain [IPR010472]	0.6896576192294276	1.719956397589623	0.0854403676625783	1.0	0.1631188961255428	3	O60879	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.6847183317771572	1.7043600076704757	0.0883138505389646	1.0	0.1652024826515598	2	O43390	1
+BRCT domain [IPR001357]	0.6932259037491312	1.6913913149761597	0.090762089952058	1.0	0.1688376847161024	11	Q9H8V3	1
+CD80-like, immunoglobulin C2-set [IPR013162]	0.6809835045129184	1.6870353566073846	0.0915965536099276	1.0	0.1700352400461877	2	Q9BY67	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.6823658309237871	1.686036190917473	0.0917888288498307	1.0	0.1702740063615098	3	P52888	1
+Zinc finger, TFIIB-type [IPR013137]	0.6778711484593773	1.672580723485389	0.0944098643115567	1.0	0.1732142572245639	2	P29083	1
+Peptidase M16, N-terminal [IPR011765]	0.6781257413809686	1.6397842026916782	0.1010500439376285	1.0	0.1800955546472387	7	P22695,O43847,Q5JRX3,Q10713	4
+Peptidase M16, C-terminal [IPR007863]	0.6781257413809686	1.6397842026916782	0.1010500439376285	1.0	0.1800955546472387	7	P22695,O43847,Q5JRX3,Q10713	4
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.6746731861041486	1.629814574288477	0.1031406925643694	1.0	0.1822333900988693	6	Q9ULV3	1
+Fibronectin type II domain [IPR000562]	0.6669246371285287	1.6139243327528674	0.1065438399993501	1.0	0.186399458468451	3	Q9UBV2	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.6610644257703024	1.5942648121961331	0.110876735429509	1.0	0.1920953803587672	2	P42695	1
+Cyclin-like [IPR013763]	0.663502319308207	1.5905305761854265	0.1117152591410501	1.0	0.1932977478669529	4	P14635,O95067	2
+VHS domain [IPR002014]	0.6598642027566274	1.573402690489568	0.1156256044228247	1.0	0.1977611840352022	4	Q9UJY5	1
+Methyl-CpG DNA binding [IPR001739]	0.6487122384023343	1.5207896197503603	0.1283126401473477	1.0	0.2116130162725988	4	Q15047,O95983	2
+EF-hand, Ca insensitive [IPR014837]	0.6441469489414682	1.5069218508291249	0.1318306898332091	1.0	0.2150287166486794	3	Q13813,P12814	2
+ARID DNA-binding domain [IPR001606]	0.6279356310116044	1.4303841332755851	0.1526067996052003	1.0	0.2340729294403158	3	O14497	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.6236087998013595	1.409912245360318	0.1585655964373657	1.0	0.2404551986791119	3	Q96G23	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.6270347896347761	1.4031394982203913	0.1605752448529351	1.0	0.2421300901812861	6	Q99956,Q9H3S7	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.6131837526723157	1.3443451511767	0.1788368013921657	1.0	0.2591486694063074	5	P98194,P23634	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.6131837526723157	1.3443451511767	0.1788368013921657	1.0	0.2591486694063074	5	P98194,P23634	2
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.6062869592281245	1.3365680917777956	0.1813636602566912	1.0	0.2616762627759704	2	Q8WUM0	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.6031449491877665	1.3129038486336937	0.1892153498753166	1.0	0.2698489456293169	3	Q07864	1
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.6031449491877665	1.3129038486336937	0.1892153498753166	1.0	0.2698489456293169	3	Q07864	1
+Post-SET domain [IPR003616]	0.6047316102941211	1.303963791562491	0.1922459281790023	1.0	0.2735414137653357	5	Q9BZ95,O96028	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.5991285403050182	1.302708381010361	0.1926743396641304	1.0	0.273783431506109	2	P51114	1
+SMCs flexible hinge [IPR010935]	0.6019503930197754	1.29066969936649	0.1968182358978198	1.0	0.278018586983549	5	Q9UQE7,Q9NTJ3,A6NHR9	3
+SET domain [IPR001214]	0.6022310315627257	1.2842784403479577	0.1990445476752453	1.0	0.2797919942360911	6	Q9BZ95,O96028	2
+MAGE homology domain [IPR002190]	0.5907251789604802	1.2629371605988138	0.2066117638160856	1.0	0.2868758112414039	2	Q96MG7	1
+FERM, C-terminal PH-like domain [IPR018980]	0.5982396715591107	1.2498391167743923	0.2113583235913534	1.0	0.2914093859586854	8	O94887	1
+FERM, N-terminal [IPR018979]	0.5982396715591107	1.2498391167743923	0.2113583235913534	1.0	0.2914093859586854	8	O94887	1
+Dynamin, GTPase domain [IPR001401]	0.5877059558289205	1.239592805748014	0.2151260429702501	1.0	0.2935418023878282	3	O60313	1
+Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]	0.584500466853416	1.23346933194822	0.2174007118207437	1.0	0.2952014741728373	2	Q9UKA9	1
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.591703038000606	1.2258031814494466	0.2202727496934406	1.0	0.297590709813108	7	Q9UJY5	1
+Rho GTPase-activating protein domain [IPR000198]	0.5849188282530059	1.2012016883775407	0.2296729746416255	1.0	0.3078032100031805	6	O00459	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.5820711638924009	1.171689317959473	0.2413218132596455	1.0	0.3190982948440691	8	P78417	1
+rRNA-processing arch domain [IPR025696]	0.5692499221911075	1.161290570067523	0.2455237530841629	1.0	0.3232165548721141	2	P42285	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.5692499221911075	1.161290570067523	0.2455237530841629	1.0	0.3232165548721141	2	P42285	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5759999892289275	1.142365563638977	0.2533020990427053	1.0	0.3308511303414241	8	Q6PK18,O60568	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5759999892289275	1.142365563638977	0.2533020990427053	1.0	0.3308511303414241	8	Q6PK18,O60568	2
+Band 4.1 domain [IPR019749]	0.5772736042436031	1.1274009971137509	0.2595729776845892	1.0	0.3359637124867107	11	O94887,Q9Y2J2,Q96AC1,P23458	4
+FERM central domain [IPR019748]	0.5772736042436031	1.1274009971137509	0.2595729776845892	1.0	0.3359637124867107	11	O94887,Q9Y2J2,Q96AC1,P23458	4
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.5675951268763574	1.1264467967271503	0.2599764482839872	1.0	0.3359637124867107	5	P51530	1
+SH2 domain [IPR000980]	0.5774443607413898	1.1161277284899576	0.2643674645461709	1.0	0.3395021448204546	13	Q06124,P23458,P12931,P41240,P19174,O00459,P62993,P46108	8
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.5586679116090919	1.1112667212209957	0.2664535593496961	1.0	0.3411983107996348	2	P46926	1
+Zinc finger, FYVE-related [IPR017455]	0.5615827808761908	1.097758601030429	0.2723099132607807	1.0	0.3467058629093709	5	Q7Z3T8	1
+FYVE zinc finger [IPR000306]	0.5615827808761908	1.097758601030429	0.2723099132607807	1.0	0.3467058629093709	5	Q7Z3T8	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.5613194732518345	1.0715696076855137	0.2839133903475037	1.0	0.3582397731979115	8	P98194,P16615,Q9HD20,P23634	4
+Kinesin-like [IPR022164]	0.5528590711811565	1.065081801489072	0.2868389138355696	1.0	0.3597976862708239	4	O60333	1
+FERM domain [IPR000299]	0.5563183032506217	1.032319901128714	0.3019222811766455	1.0	0.3716714690048444	10	O94887,Q9Y2J2,P23458	3
+SANT domain [IPR017884]	0.5561490996360792	1.031500695879458	0.3023060820576837	1.0	0.3719480591165531	10	Q8TAQ2,P28370,Q99543	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.5484227973265198	1.026500372494369	0.3046557881337945	1.0	0.3741754973635907	6	Q9NUQ2	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.559443640324928	1.0218800981954317	0.3068376529844732	1.0	0.3757223813307651	14	Q9UHX1,O95628,Q14011,Q9Y4C8,Q14498,Q01130,Q01085	7
+Ribosome receptor lysine/proline rich [IPR007794]	0.5356364768129585	1.0027827919167769	0.3159656733124789	1.0	0.3803817174216387	2	Q86UP2	1
+Tudor domain [IPR002999]	0.545402132858348	0.9951018445940272	0.319686733608268	1.0	0.3845152933462756	8	Q14739,Q8NHU6	2
+Fumarate lyase, N-terminal [IPR022761]	0.5337690631808344	0.9940213668418824	0.3202124652198852	1.0	0.3849745368373901	2	P30566	1
+Myb domain [IPR017930]	0.5427162633145944	0.9822406704538198	0.325981295574608	1.0	0.3894144030781892	8	Q8TAQ2,Q99543	2
+CRIB domain [IPR000095]	0.5294117647058891	0.973604065405365	0.3302531670000925	1.0	0.3922856224357227	2	Q13153	1
+p21 activated kinase binding domain [IPR033923]	0.5294117647058891	0.973604065405365	0.3302531670000925	1.0	0.3922856224357227	2	Q13153	1
+Kinesin-associated [IPR032405]	0.5300574149615047	0.9572930229387552	0.3384193759401321	1.0	0.3986517553243585	4	O60333	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.5277085927770843	0.9557707311711447	0.3391880786052694	1.0	0.3989252952767367	3	P08243,Q06210	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.5311535270120427	0.9532799751001788	0.3404482347111375	1.0	0.3998975281068318	5	Q6PK18	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.5270722358845625	0.95278750872455	0.3406977445067176	1.0	0.3998975281068318	3	Q08426	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.5270722358845625	0.95278750872455	0.3406977445067176	1.0	0.3998975281068318	3	Q08426	1
+Intermediate filament, rod domain [IPR039008]	0.5344696109738427	0.9428465973499632	0.3457593734136506	1.0	0.4037129305462746	8	P07196,P02545,P48681,P08670	4
+Replication factor C, C-terminal [IPR013748]	0.5230386052303841	0.9339002623029607	0.3503553435331314	1.0	0.4081883902226161	3	P40937,P35250	2
+Sorting nexin, N-terminal [IPR005329]	0.5185185185185215	0.9227433061628364	0.3561409919217584	1.0	0.4136678911813737	2	O60749	1
+Domain of unknown function DUF1605 [IPR011709]	0.5292628912929829	0.8945768002824168	0.3710133581447037	1.0	0.4261317016045867	11	Q92620,Q14562	2
+Helicase-associated domain [IPR007502]	0.5292628912929829	0.8945768002824168	0.3710133581447037	1.0	0.4261317016045867	11	Q92620,Q14562	2
+Aminotransferase, class I/classII [IPR004839]	0.5213044154818101	0.8889578799363311	0.3740257169248926	1.0	0.4282563117190008	7	Q8TD30	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.5079365079365209	0.8736362446718242	0.3823163812868579	1.0	0.4333305671988002	2	Q13641	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.5079365079365209	0.8736362446718242	0.3823163812868579	1.0	0.4333305671988002	2	Q13641	1
+Ubiquitin-associated domain [IPR015940]	0.5227280870606995	0.856086049748848	0.391950184364116	1.0	0.4399776513529208	12	Q04323,Q14157,Q9BSL1,Q9Y5A7,Q9UPU5,P54725	6
+W2 domain [IPR003307]	0.5125471356549567	0.8477601880323875	0.3965715391002493	1.0	0.4423655564454644	7	P55010,Q13144	2
+Myosin, N-terminal, SH3-like [IPR004009]	0.5065377534254617	0.8379189736639235	0.4020762118035752	1.0	0.4472819945781762	5	P35580,Q7Z406,Q92614	3
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.4472819945781762	2	Q9H9Y6	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.4472819945781762	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.4472819945781762	2	Q9H9Y6	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.4472819945781762	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.4998443821973301	0.836325492346752	0.4029718156760391	1.0	0.4472819945781762	2	Q9H9Y6	1
+B-box-type zinc finger [IPR000315]	0.5078902913096175	0.8351066488460739	0.4036576634445004	1.0	0.4478574241866605	6	P19474,O15344	2
+Zinc finger, RanBP2-type [IPR001876]	0.510617747983089	0.8215225898876343	0.4113486621783089	1.0	0.4560122964471513	9	Q92804,P98175	2
+CAP Gly-rich domain [IPR000938]	0.5004687436594721	0.8192838800593268	0.4126244674635841	1.0	0.4572371377237313	4	Q14203,Q15813	2
+Serine/threonine-protein kinase N, C2 domain [IPR037784]	0.4957983193277449	0.8177599339248908	0.4134942802061667	1.0	0.4578216885560828	2	Q16513	1
+Serine/threonine-protein kinase N, first HR1 domain [IPR037313]	0.4957983193277449	0.8177599339248908	0.4134942802061667	1.0	0.4578216885560828	2	Q16513	1
+Formin, FH2 domain [IPR015425]	0.4932444113044983	0.7860556787894801	0.4318348683630331	1.0	0.4759613814878918	4	O60879	1
+Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]	0.4932444113044983	0.7860556787894801	0.4318348683630331	1.0	0.4759613814878918	4	O60879	1
+Proteasome component (PCI) domain [IPR000717]	0.5155751047804663	0.7855316659784154	0.4321419117084237	1.0	0.4761036300741489	18	Q96PV6	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.4962675777684242	0.7811920702446915	0.4346895369077357	1.0	0.4785162597646885	6	P51530	1
+Forkhead-associated (FHA) domain [IPR000253]	0.5077085288603959	0.7774693938187502	0.4368818848836366	1.0	0.4805341455854145	13	Q14BN4	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.4847447073474452	0.757166920708559	0.4489498654893049	1.0	0.4919872552986033	3	P51116,P51114	2
+Agenet-like domain [IPR008395]	0.4847447073474452	0.757166920708559	0.4489498654893049	1.0	0.4919872552986033	3	P51116,P51114	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.4847447073474452	0.757166920708559	0.4489498654893049	1.0	0.4919872552986033	3	P51116,P51114	2
+Fxr1, tudor domain [IPR041560]	0.4847447073474452	0.757166920708559	0.4489498654893049	1.0	0.4919872552986033	3	P51116,P51114	2
+Dynamin GTPase effector [IPR003130]	0.4796140678493676	0.7441982538438681	0.4567565442772925	1.0	0.4993149799516785	2	P50570	1
+GTPase effector domain [IPR020850]	0.4796140678493676	0.7441982538438681	0.4567565442772925	1.0	0.4993149799516785	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.4796140678493676	0.7441982538438681	0.4567565442772925	1.0	0.4993149799516785	2	P50570	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.474634298163712	0.7218206278251829	0.4704047654243013	1.0	0.5133956538188519	2	Q14240	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.4902443838123687	0.7103014581696147	0.4775172157754286	1.0	0.5207332051362705	11	P78417	1
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.4718331777155322	0.7092927977266266	0.4781427969396006	1.0	0.5212029265743405	2	P43246	1
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.4719800747197988	0.6996747157323816	0.4841304701560511	1.0	0.5258014647452037	3	P43246,P20585	2
+DNA mismatch repair protein MutS, core [IPR007696]	0.4719800747197988	0.6996747157323816	0.4841304701560511	1.0	0.5258014647452037	3	P43246,P20585	2
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.4719800747197988	0.6996747157323816	0.4841304701560511	1.0	0.5258014647452037	3	P43246,P20585	2
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.4719800747197988	0.6996747157323816	0.4841304701560511	1.0	0.5258014647452037	3	P43246,P20585	2
+Fatty acyl-CoA reductase, C-terminal [IPR033640]	0.468409586056647	0.6940423920576283	0.4876556241912388	1.0	0.5289857237273171	2	Q96K12	1
+Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]	0.468409586056647	0.6940423920576283	0.4876556241912388	1.0	0.5289857237273171	2	Q96K12	1
+Ras GTPase-activating domain [IPR001936]	0.4735271347914364	0.6869594545719057	0.4921082790328075	1.0	0.5333831630521718	5	P21359	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.4827029657178339	0.6836004066635163	0.494227527818611	1.0	0.5354631984264012	10	Q9UNK0,O43752,O95721,Q13190	4
+CID domain [IPR006569]	0.4707165109034149	0.6743756432773225	0.5000725238017916	1.0	0.5415765186922237	5	Q8IWX8,Q5VT52,O15042,Q9NQG5	4
+FAD/NAD(P)-binding domain [IPR023753]	0.4690455353391487	0.6669180418703897	0.5048244859370228	1.0	0.5456183837905195	5	Q16881,O95831	2
+Spt5 C-terminal domain [IPR024945]	0.4618736383442268	0.6651267261637785	0.505969441751668	1.0	0.5466349986614346	2	O00267	1
+ABC-transporter extension domain [IPR032781]	0.46125116713352	0.6623871110991216	0.5077231617972346	1.0	0.5483082187354068	2	Q9NUQ8	1
+Nucleotidyl transferase domain [IPR005835]	0.4632627646326257	0.6609556451266476	0.5086407589351998	1.0	0.5490774940079336	3	Q96IJ6,Q9NR50	2
+CS domain [IPR007052]	0.4751803496317715	0.6493643616565932	0.516102893647207	1.0	0.5566835647202736	10	Q8IVD9,Q9Y2Z0	2
+Transcription elongation factor S-II, central domain [IPR003618]	0.4597618698749217	0.6455448445263978	0.518574167065359	1.0	0.558898427437484	3	P23193	1
+Glycoside hydrolase family 31, N-terminal domain [IPR025887]	0.4550264550264712	0.635135477710378	0.5253400602219247	1.0	0.5659576113239747	2	Q14697	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.4563866130852217	0.6307676629206516	0.5281924500003075	1.0	0.5681201462608856	3	Q16881	1
+PWWP domain [IPR000313]	0.4679249252273124	0.6167120644843932	0.5374246621662377	1.0	0.5773538037328056	10	O95696,O96028,Q9BZ95	3
+SANT/Myb domain [IPR001005]	0.4700549280287813	0.6102667110642567	0.5416851446997653	1.0	0.5816972148020362	12	Q8TAQ2,P28370,Q99543	3
+Heavy metal-associated domain, HMA [IPR006121]	0.4491129785247436	0.6095033017227702	0.5421908849249601	1.0	0.5817732118629235	2	P35670	1
+Heavy metal-associated domain, copper ion-binding [IPR006122]	0.4491129785247436	0.6095033017227702	0.5421908849249601	1.0	0.5817732118629235	2	P35670	1
+CLASP N-terminal domain [IPR024395]	0.4478680361033306	0.6041407442832554	0.5457500728293387	1.0	0.5853574357732483	2	Q7Z460	1
+Zinc finger, CCHC-type [IPR001878]	0.4585411471321771	0.6015889031347625	0.5474478173107298	1.0	0.5869430506237283	7	Q5TAX3,Q16629,Q6NZY4,Q7Z6E9,Q9NUD5,Q15637	6
+DnaJ domain [IPR001623]	0.4767955187351531	0.5902377768388752	0.5550312488198752	1.0	0.5948351725132878	20	Q9UBS4,Q13217,Q96KC8,Q99543,Q9Y2G8,Q9UGP8,O75937	7
+Intermediate filament head, DNA-binding domain [IPR006821]	0.4482685860261182	0.5855703628596589	0.5581642695299296	1.0	0.5974747583003448	4	P07196,P08670	2
+Zinc finger, RING-type [IPR001841]	0.4797882949476547	0.5780940493857456	0.5632006243387044	1.0	0.6023837145565911	27	O95628,P19474,O94822,O75592,O15344,Q5W0B1,Q96T51,Q99496,P38398,O96028	10
+B3/B4 tRNA-binding domain [IPR005146]	0.4416433239962685	0.5775133967306343	0.5635926913628515	1.0	0.6025621300542078	2	Q9NSD9	1
+TOG domain [IPR034085]	0.448426301028364	0.5670793743771818	0.5706602553719862	1.0	0.6089015489110742	6	Q7Z460,Q86Y56,Q92616,O00410,Q8TEX9	5
+GCF, C-terminal [IPR022783]	0.4347622908564884	0.5382066643079688	0.5904343796544143	1.0	0.6289971985565743	3	Q9UBB9	1
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.437687477569363	0.5119236715353221	0.6087044304699587	1.0	0.6467991178416126	7	Q9ULV3	1
+RNA polymerase, alpha subunit [IPR000722]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+RNA polymerase Rpb1, domain 3 [IPR007066]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+RNA polymerase Rpb1, domain 4 [IPR007083]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+RNA polymerase Rpb1, domain 1 [IPR007080]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+RNA polymerase Rpb1, domain 5 [IPR007081]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+RNA polymerase, N-terminal [IPR006592]	0.4271847341319574	0.506752417319645	0.6123285466799127	1.0	0.6487044999480263	3	O14802	1
+GAR domain [IPR003108]	0.4170557111733719	0.4757545519342886	0.6342492516791878	1.0	0.6705995052339239	2	Q9UPN3	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.4193648816936465	0.474901797982463	0.6348569698516993	1.0	0.6707118461110961	3	P61289,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.4193648816936465	0.474901797982463	0.6348569698516993	1.0	0.6707118461110961	3	P61289,Q9UL46	2
+SPRY domain [IPR003877]	0.4231769851290096	0.4255530769054565	0.670433538072249	1.0	0.7057889470064015	10	P19474,O15344,Q12899	3
+B30.2/SPRY domain [IPR001870]	0.4231769851290096	0.4255530769054565	0.670433538072249	1.0	0.7057889470064015	10	P19474,O15344,Q12899	3
+LEM domain [IPR003887]	0.4134575613202803	0.4225602324565296	0.6726161462510416	1.0	0.7078081004018633	6	Q86XL3	1
+Ran binding domain [IPR000156]	0.4011211460604197	0.393592453511334	0.6938819536582028	1.0	0.7283153881683938	4	Q9H6Z4,P49792,P43487	3
+Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]	0.41069408968569	0.3934194704052109	0.6940096913799012	1.0	0.7283153881683938	8	O94967	1
+Myosin head, motor domain [IPR001609]	0.4045217478847048	0.3696860805056918	0.7116164043394089	1.0	0.7453304156648076	8	P35580,Q7Z406,Q92614	3
+FF domain [IPR002713]	0.3885429638854273	0.3563876497265503	0.7215502771074216	1.0	0.7542583006105325	3	O75400,Q13017	2
+NOPS [IPR012975]	0.3801369863013676	0.3262994601604361	0.7441977966243694	1.0	0.7770215089657252	3	Q15233,P23246	2
+Ubiquitin-like domain [IPR000626]	0.4078370362738533	0.3197375446079041	0.7491672961168079	1.0	0.7812953283089518	16	Q8NCF5,P54725,O14920	3
+AP complex, mu/sigma subunit [IPR022775]	0.380555221714324	0.3003211861158038	0.763932174487052	1.0	0.7945251037141773	6	Q92572,P61923	2
+Ubiquitin system component CUE [IPR003892]	0.3742888275585371	0.296738441896145	0.7666662057793125	1.0	0.7966091623489645	4	Q9H1I8	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.382054674379203	0.2966382968425594	0.7667426694949979	1.0	0.7966091623489645	7	Q9C0C9,P49427	2
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.3776994221411687	0.273060288926696	0.7848068719199517	1.0	0.8137047993743685	8	Q15118	1
+ROCK, Rho binding domain [IPR015008]	0.3613445378151251	0.2722595783196372	0.7854224344268574	1.0	0.8140275134024966	2	O75116	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.3615696044845867	0.2547801881221438	0.7988928780027162	1.0	0.8270272634122551	4	O75116,Q92974,Q9H0H5	3
+HR1 rho-binding domain [IPR011072]	0.3615696044845864	0.2547801881221433	0.7988928780027167	1.0	0.8270272634122551	4	O75116,Q16513,Q16512	3
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.3609467455621329	0.2527967532936863	0.800425276730536	1.0	0.8282930813362412	4	P08238,P07900,P14625	3
+EF-hand domain [IPR002048]	0.4092327079117711	0.2360329710747478	0.8134070856563334	1.0	0.8391299476015008	42	O75071,Q9NWM8,P80303,O75340,Q9UBC2,Q9Y680,Q02818,Q14257,Q96AY3	9
+Initiation factor eIF-4 gamma, MA3 [IPR003891]	0.3602368339046489	0.2332742921127539	0.8155484198987053	1.0	0.8406905677183186	6	P78344,O43432,Q9HCG8,Q53EL6,Q5C9Z4	5
+DZF domain [IPR006561]	0.3525381501090027	0.2266988107959629	0.8206579518923032	1.0	0.8447008382518297	4	Q12906,Q12905,Q96SI9	3
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.3540063828566491	0.2225667263775708	0.8238727353861406	1.0	0.8476382950607408	5	P12931,P23458	2
+Zinc finger, LIM-type [IPR001781]	0.3569509515707335	0.1908558990821397	0.848638492401411	1.0	0.871442597763445	10	Q8N3F8	1
+Chromo/chromo shadow domain [IPR000953]	0.3513098172004759	0.1898555947734025	0.8494222897424846	1.0	0.8719127494478688	8	Q8TAQ2	1
+Transcription factor IIS, N-terminal [IPR017923]	0.3389510337353483	0.1872994917602708	0.8514258214520789	1.0	0.873634089905758	4	P23193	1
+Phox homology [IPR001683]	0.3573622100961661	0.1845297069301399	0.8535979245291345	1.0	0.8755270123142005	11	Q9Y5X3	1
+Helicase, C-terminal [IPR001650]	0.3727874409106895	0.1675137450799256	0.8669658333264016	1.0	0.8888975102139227	65	O14981,Q92620,Q9H8H2,Q2NKX8,P19447,Q14191,Q8N8A6,Q14562,Q9UPY3,P28370,Q8IYB8	11
+Band 7 domain [IPR001107]	0.3397027173500365	0.1574505513902455	0.8748897759937246	1.0	0.8956487373835489	8	P27105	1
+Sec63 domain [IPR004179]	0.3228518057285157	0.1531981010178594	0.8782420551642167	1.0	0.8980495021270183	3	Q9UGP8,Q8N3C0	2
+RNA-binding domain, S1 [IPR022967]	0.3374070437750385	0.1513615661419112	0.8796905058791671	1.0	0.8991868946223813	8	Q14562	1
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.325132357521024	0.150916892248409	0.8800412750225548	1.0	0.8992018375421444	4	P49588,Q9BW92,Q5JTZ9	3
+Serpin domain [IPR023796]	0.3174603174603186	0.1480545707416596	0.8822997015248342	1.0	0.9011652163340708	2	P35237	1
+Double-stranded RNA-binding domain [IPR014720]	0.3565901746781365	0.1474923877258477	0.882743387736316	1.0	0.9012742603796356	16	Q96SI9,O95793,Q9NUL3,Q9UPY3,O75569	5
+PDZ domain [IPR001478]	0.3686853807524337	0.1368471714093333	0.8911515969594732	1.0	0.9095118358895806	24	Q8TEU7,Q96RT1,O00560,Q92614,P57105	5
+BZW1/2, W2 domain [IPR043510]	0.3118580765639545	0.1349115961866125	0.8926817709461075	1.0	0.91072606303617	2	Q9Y6E2	1
+Syntaxin, N-terminal domain [IPR006011]	0.3147571606475691	0.1337951206583253	0.893564585655721	1.0	0.9111388827211442	3	Q12846,O15400	2
+Helicase superfamily 1/2, ATP-binding domain [IPR014001]	0.3636844690135887	0.1194276329329144	0.9049365700436394	1.0	0.9211207476661856	65	O14981,Q92620,Q9H8H2,P38935,Q2NKX8,P19447,Q14191,Q8N8A6,Q14562,Q9UPY3,P28370	11
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.2964808470881372	0.0879054109553763	0.9299518559354788	1.0	0.9419239737324522	4	Q9UBQ7,Q13363,O43175	3
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.2964808470881372	0.0879054109553763	0.9299518559354788	1.0	0.9419239737324522	4	Q9UBQ7,Q13363,O43175	3
+WW domain [IPR001202]	0.3265750379422625	0.0834287447872995	0.9335106331430356	1.0	0.9448130698666743	14	P46934,Q8N1G2,Q13526	3
+SNF2, N-terminal [IPR000330]	0.3261139575719939	0.0761763043264802	0.9392788343101556	1.0	0.9499322804459984	15	O14981,Q9H4L7,Q9P2D1,Q2NKX8,P28370	5
+AMP-dependent synthetase/ligase [IPR000873]	0.2984475585139809	0.071270017289681	0.9431828572675884	1.0	0.9535200843502644	7	Q9P265	1
+Rab-GTPase-TBC domain [IPR000195]	0.2885365397547927	0.0603365571056867	0.951887586610734	1.0	0.9615933890421878	6	Q66K14,Q8TC07,Q4KMP7	3
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.2690195715485315	0.0494445405649163	0.9605650333101194	1.0	0.9699930026819816	3	Q86UV5	1
+HECT domain [IPR000569]	0.2765169555567852	0.018594113330867	0.9851648989069808	1.0	0.993334377902817	10	Q05086	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.2355140186915957	0.0031339286426555	0.9974994908144968	1.0	1.0	5	Q15436,O95487,Q15437,P53992	4
+Sec23/Sec24, helical domain [IPR006900]	0.2355140186915957	0.0031339286426555	0.9974994908144968	1.0	1.0	5	Q15436,O95487,Q15437,P53992	4
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.2355140186915957	0.0031339286426555	0.9974994908144968	1.0	1.0	5	Q15436,O95487,Q15437,P53992	4
+Sec23/Sec24, trunk domain [IPR006896]	0.2355140186915957	0.0031339286426555	0.9974994908144968	1.0	1.0	5	Q15436,O95487,Q15437,P53992	4