diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..08f212a279711d8e476701fdc56d6ad2504edba3 --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1fb412e3333a36ae5fab6f64f8a2c9d154b6a902185aec27023463a6b2d1568 +size 149108 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..49a2f1675b15d18dc45b052efe95d5220897a182 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e33755e05b658b2559e36c368513f3706b1e590ed3f207cf72160876240d737d +size 80472 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5ce7e51900a28ee3138a6e89838b8b96480cd6dc --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 58, + "title": "Average number of proteins per term", + "value": 2.810344827586207 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..80aa3dde2db60f5f4b63215fcb6f77ebf7f68882 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..10f063101d7f0496a6c65cf624d9c768fb2eaa09 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein-tyrosine phosphatase, active site [IPR016130] 0.6416868398401682 1.957887304439852 0.0502432379321107 0.9497056881012432 0.2081505571473158 9 Q13614,P51452,O60942,Q8NCE2 4 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.6727591129607006 1.3943011832104686 0.1632266737822698 0.9999675470627468 0.3492556166045542 5 P49427,Q16763,P68036 3 +Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.8206251825883737 1.382176629572631 0.166917474085116 0.9999748866032157 0.3492556166045542 2 Q9NQ88 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.3151490896455099 1.2911593670755273 0.1966484215949067 0.9999969483988062 0.3758079535056106 60 Q99570,P36507,P33981,P24941,P51617,Q16512,Q99640,P48729,Q00534,Q02750,Q9H4A3,Q14012,P17612,Q96KB5,P19525,P31751,P49841,Q13177,Q13546,Q99986,Q00535,Q96SB4,P10398,P19784,O14965 25 +Nucleoside diphosphate kinase, active site [IPR023005] 0.6925859678706816 0.8455107443146228 0.3978257363552182 0.9999999999998326 0.5627778709415282 3 P15531 1 +L-lactate dehydrogenase, active site [IPR018177] 0.6409582237803145 0.6586046987034349 0.5101496448293326 1.0 0.6164308208354435 2 P00338 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.6202273558788243 0.5885815044572303 0.5561420441080656 1.0 0.6180648248007394 3 Q9UBT2 1 +Cysteine peptidase, cysteine active site [IPR000169] 0.4641917567962721 0.4250474372299238 0.6708020941196859 1.0 0.7204911381285516 4 Q13867,P17655,P53634 3 +Tyrosine-protein kinase, active site [IPR008266] 0.3692982456140335 0.2131592840952171 0.8312027249969631 1.0 0.876541055451343 5 P41240,Q05397,P07948,Q13308 4 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c36db853d8f4eebf715cbde037cabebb4c4a5a3d --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AKT3", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CDC34", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MARK3", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME6", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "AURKA", "BLMH", "CAMK1", "CAPN2", "CDC34", "CDK2", "CDK5", "CDK6", "CSK", "CSNK1A1", "CSNK2A2", "CTSC", "DUSP3", "EIF2AK2", "GSK3B", "IRAK1", "LDHA", "LYN", "MAP2K1", "MAP2K2", "MTMR14", "MTMR2", "NME1", "PAK2", "PBK", "PIK3R4", "PKMYT1", "PKN1", "PRKACA", "PTK2", "PTK7", "RIPK1", "RNGTT", "SRPK1", "TIGAR", "TTK", "UBA2", "UBE2L3", "UBE2S", "VRK1", "WNK1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1c0dc834f5e790aabb2e32b3ee6fb397fabe2c0c --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1b619e90cfd7a6f63d0280c49e3c5eab1e6c45ca --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0917991a319cea0142d418fbb7066c3da45d519652fb7e69d9f876022d5f8e2 +size 147055 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8f6e12885cb66c12b9b2f5ec6fdde336e5879968 --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d42ee3dd9b88f360c90dbc1875f79084b2797fb09d56dfbac6e350842e13af9f +size 146699 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5e98a4c372585445ed84f067dd680b87f2181925 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8510f9791cdec8b5f7d3dee0de9bb1fa3d45f91635ba2876ae263682c7135ef +size 78939 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..956fed9b2f6b6abf7954c993a66a20c5404598b0 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.225806451612903 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..afa9df73ea4070fdedd83c5718d59cd5033fe59d --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..57fdbf6605f574176bd022ba7d0aa40c4bc31d07 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein kinase, ATP binding site [IPR017441] 0.3472202529980679 1.6333648531826344 0.1023922844292219 0.9648695359272575 0.2246979244852183 59 P36507,P33981,Q13131,Q13043,P24941,P51617,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9P289,Q14012,P17612,P19525,P31751,P49841,O75116,Q13177,Q99986,Q00535,P41240,Q96SB4,P10398,Q9NYV4,O14965,P19784,O95747,P06493 30 +Beta tubulin, autoregulation binding site [IPR013838] 0.6693695146902517 1.5952209706813745 0.1106628308682551 0.973633058587336 0.2246979244852183 6 P07437,Q9BUF5,Q9BVA1 3 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.7437919953257408 1.0628816734539972 0.287835614950473 0.9999730854091206 0.4461452031732332 2 O15355 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.2653843515626173 0.5985928774308346 0.5494444068901911 0.9999999999815412 0.7096990255664969 41 Q9UBC2,Q96AY3,O43852,P41208,P0DP25 5 +IQ motif, EF-hand binding site [IPR000048] 0.3369206327959516 0.4717925153631536 0.6370748938001094 0.9999999999999774 0.7595892964539765 12 Q15051 1 +Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.3169734151329206 0.0414637211497177 0.966926214296137 1.0 0.9991570881060082 2 Q9UQ80 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d217c3dff7cd4d5f403557ecdcc3bf9e3550eff1 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "AKT3", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NEK1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "AURKA", "CALM3", "CALU", "CAMK1", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CETN2", "CSK", "CSNK1A1", "CSNK2A2", "EIF2AK2", "EPS15L1", "FKBP10", "GSK3B", "IQCB1", "IRAK1", "MAP2K1", "MAP2K2", "MAPK14", "OXSR1", "PA2G4", "PAK2", "PKMYT1", "PKN1", "PPM1G", "PRKAA1", "PRKACA", "ROCK2", "SRPK1", "STK26", "STK4", "TTK", "TUBB", "TUBB2B", "TUBB6", "VRK1"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2d87a456c859f7d763df70f2e8915263713ecf7 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2e86758202a0bd9a88101374166ccd713e14e1c4 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfec1aa4bbf71e274439d98f8d865dd724f3b9a1a1f7be1fb6c709015c31ac65 +size 192218 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a42fe3a5227006f396eadb096735f63eec9fd7a0 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "14-3-3 protein, conserved site [IPR023409]", "2": "Chaperonin TCP-1, conserved site [IPR002194]", "3": "DnaJ domain, conserved site [IPR018253]", "4": "ATPase, AAA-type, conserved site [IPR003960]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8c4aafb87221e1ff8d039f502a80e0493df71b21 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21ae363938a71846f6f73c3ece0da6922d9dc3e5bf337300587da6af24babc01 +size 135469 diff --git 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0000000000000000000000000000000000000000..29fbb5e0c039af8c024f7fa84cec525a2a27061a --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0a8ba752a1030085f61204b27e6b027fd0cf836dda27f9c68f4ce183262f493 +size 142481 diff --git a/interpro_conserved_site/basic/plot_4.png b/interpro_conserved_site/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..21648273c2ea30c54231bcc2b8e35ad37d8a4c01 --- /dev/null +++ b/interpro_conserved_site/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5632c6c42d23be3d3a9a8ea36f35e07984f76897f676d6b45c84e8e5ff72f764 +size 156300 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7295dbf902d533379f2f118e6111011170b28acd --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e158db3618cef30fe4aac957714c8c62811967b0f49d640fc99d83e24d674b89 +size 113746 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..934a1881a8d971b43e52644b13120878e2ce6ab4 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 7 8 3.102730848402799 0.0019174393840755 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.148254609278584e-05 9.839858993160587e-05 5.22260781759681e-10 1.22573214543153e-09 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 1 5 2.343781263498936 0.0190893630126129 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002150789234385 0.0008973897437505 0.0056136137273067 0.0214122317398669 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c74e056c556bc620bbcc40fa85a39e7a92ed44d7 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 284, + "title": "Average number of proteins per term", + "value": 2.8450704225352115 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c5698a0951ff2478238382aa35329066cd10e0f8 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..600a71effd468736d52961e7ef190f519dbbb5f6 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,41 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.9075212174422068 3.102730848402799 0.0019174393840755 0.4202020086471177 0.0599907167853119 8 P20618,Q99436,P49721,P28072,P28070,P28074,P49720 7 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8964725207226569 2.343781263498936 0.0190893630126129 0.9958047088208096 0.0903563182597015 5 P48735 1 +Chromo domain, conserved site [IPR023779] 0.6953962894123901 1.9094353254936849 0.056205957388544 0.9999999266949666 0.1666197344765188 7 Q12873,P83916,O14646 3 +14-3-3 protein, conserved site [IPR023409] 0.7130739982451005 1.7945239204549257 0.072729584127241 0.9999999995140196 0.1948887571757021 6 Q04917,P61981,P27348,P63104,P31946 5 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.6703289396348417 1.7901127422580114 0.0734357887562169 0.9999999996085754 0.1948887571757021 7 Q13535,P42356,Q96Q15 3 +Profilin conserved site [IPR027310] 0.8816827344434759 1.6377613549839911 0.1014714860278738 0.9999999999999364 0.252788614315054 2 P07737 1 +Tubulin, conserved site [IPR017975] 0.6217076785885784 1.5553138952532628 0.119871329625719 0.9999999999999998 0.2689442811375302 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Clathrin adaptor complex, small chain [IPR000804] 0.8695854771094825 1.52722794727679 0.1267043391331583 1.0 0.2811252524516951 3 P61923 1 +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.8340636868244257 1.4384545034654566 0.1503051375826967 1.0 0.3185571572648198 2 P30046 1 +Purine phosphorylase, family 2, conserved site [IPR018099] 0.8215016067776933 1.3858457551124714 0.1657940075434263 1.0 0.3429363562441447 2 Q13126 1 +Chaperonin TCP-1, conserved site [IPR002194] 0.546551328193488 1.363931884570491 0.1725890046517295 1.0 0.3476260802914269 8 P17987,P50991,P78371,P40227,P48643,P49368 6 +Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842] 0.8042652643879697 1.313739977431123 0.188933722703636 1.0 0.3708282238596381 2 P11908 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.7890739117732978 1.2503309987817213 0.2111786590968121 1.0 0.3971837032019513 2 P15880 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.7940766533662522 1.2329936549372809 0.2175781314599481 1.0 0.4065275614120083 3 O15347 1 +DnaJ domain, conserved site [IPR018253] 0.4335661736102129 0.9384322457496836 0.3480223211091973 1.0 0.5552715685113034 11 O60884,Q99543,P25685,P31689,Q8WXX5 5 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.7002629272568077 0.8867261222231335 0.3752263708922703 1.0 0.582318520947567 2 P29692 1 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.679228746713423 0.8038738130779437 0.4214698551143501 1.0 0.6201939836915825 2 P06737 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.6321796357923907 6 P33992,P25205,P33991,P49736 4 +Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.6580701459307636 0.7198757755861208 0.4716014842636775 1.0 0.6630436709449723 3 Q96G03 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.6380368098159555 0.6478680578571997 0.5170702919557322 1.0 0.6996495351290343 2 P50570 1 +F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.6348232544551644 0.6361233663541203 0.5246960167513768 1.0 0.7048137250386391 2 P47755 1 +Ubiquitin interacting motif [IPR003903] 0.5183673774310886 0.618750322545884 0.5360808530865016 1.0 0.7048137250386391 4 Q92783 1 +CBX family C-terminal motif [IPR033773] 0.6222611744084292 0.5909069262744483 0.5545827849185287 1.0 0.709466265391271 2 Q9HC52 1 +Cullin, conserved site [IPR016157] 0.4781428275970755 0.5669855506341906 0.5707239986469617 1.0 0.7140335489680049 5 Q93034,Q13620,Q13616 3 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.60998387510767 0.5545109882001815 0.5792291877248656 1.0 0.7183453681828028 3 Q9GZZ9 1 +Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.5980134385042414 0.50710625631177 0.6120802654854756 1.0 0.7391093833197412 2 Q00796 1 +FERM conserved site [IPR019747] 0.3503863265326897 0.4704418822879731 0.6380393472683958 1.0 0.7613578765723715 10 P15311,P26038,Q9Y4F1,Q9Y2J2 4 +GHMP kinase, ATP-binding, conserved site [IPR006203] 0.5749342681858133 0.4322588137452762 0.6655533177433182 1.0 0.7843034947680596 2 P51570 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.5717207128250144 0.4222607334351904 0.6728347158481678 1.0 0.7896076830614862 2 P04066 1 +GTP1/OBG, conserved site [IPR006074] 0.5676307332749164 0.4096948780412297 0.6820297878206576 1.0 0.7971047725969825 2 P55039 1 +Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.5600350569675843 0.3868437670782049 0.6988718734471102 1.0 0.8075680221057465 2 Q9NQW7 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.5597429155711482 0.3859777518957347 0.6995131459084987 1.0 0.8075680221057465 2 P28340 1 +Phosphofructokinase, conserved site [IPR015912] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.8371996427526305 3 P08237 1 +Aldo/keto reductase, conserved site [IPR018170] 0.5384165936313292 0.325461169286839 0.7448320666528603 1.0 0.8427581949378976 2 P15121 1 +Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.5243938066024102 0.2887301462622583 0.7727878913541775 1.0 0.8640620517503401 2 P04075 1 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.3849751534638996 0.2013123589545192 0.8404543393399684 1.0 0.9215792755696952 4 O43175,Q13363,Q9UBQ7 3 +Ribosomal protein S9, conserved site [IPR020574] 0.4279871457785641 0.1093389907274998 0.9129336218370956 1.0 0.985829462364012 2 P62249 1 +ATPase, AAA-type, conserved site [IPR003960] 0.1998748802849937 0.0636968040562368 0.9492116495747842 1.0 0.9964872988726112 19 P62195,Q9UN37,P62333,Q15645,O75351,P17980 6 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.3682408310382033 0.0609616675819248 0.9513897370871852 1.0 0.9964872988726112 3 Q9H8V3 1 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.3204791118901499 0.0421760429341406 0.9663583605316336 1.0 1.0 2 P06730 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..757a042224742ba1bfd6cf5c77891e6db87e7041 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB1", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPH7", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH1", "IMPDH2", "INA", "ING5", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF169", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAF5", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "UIMC1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AKR1B1", "ALDOA", "ATR", "CAPZA2", "CBX1", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CHD1", "CHD3", "COPZ1", "CTBP1", "CUL1", "CUL4B", "CUL5", "DDT", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC2", "DNAJC9", "DNM2", "DRG2", "ECT2", "EEF1D", "EIF4E", "EPB41L3", "EZR", "FARP1", "FUCA1", "GALK1", "GRHPR", "HMGB3", "IDH2", "MCM2", "MCM3", "MCM4", "MCM5", "MSN", "MTAP", "PFKM", "PFN1", "PGM2", "PHGDH", "PI4KA", "POLD1", "PRPS2", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMC5", "PSMC6", "PYGL", "RPS16", "RPS2", "SMG1", "SORD", "STAM", "TCP1", "TRIP13", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "UBA5", "VPS4A", "VPS4B", "XPNPEP1", "YWHAB", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]} \ 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b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8f0cc9e52ec2ef9400df479170c187ecb400d624 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa509f6d43a9a8e94669cc1b3411a50f393f0c7ff8de52b390f02916d7609625 +size 426208 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..78b9c4efb778ea48578f7dad0447197e825e9fd8 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 5 7 2.66950152293713 0.0075963928629572 3.3640776699029127 7.0 -0.0819805286147498 0.4543740069752794 1.9566840569754116 0.0 1.1177702159542848 0.3184279071165019 1.0 1.0 1.0 0.0004628530549595 8.641434277596474e-08 +Isopropylmalate dehydrogenase-like domain [IPR024084] 1 5 2.343781263498936 0.0190893630126129 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002150789234385 0.0008973897437505 0.0056136137273067 0.0214122317398669 +SPRY domain [IPR003877] 1 11 2.281382243499555 0.0225258378334338 3.907766990291262 10.905339805825244 -0.121384165939116 0.5786714434021809 2.5459348644566675 1.8508121101441584 0.8186540272344984 0.2959289197143789 1.0 0.0165768393094286 0.0614247268920475 0.2722557910873528 0.612992755958387 +B30.2/SPRY domain [IPR001870] 1 11 2.281382243499555 0.0225258378334338 3.907766990291262 10.905339805825244 -0.121384165939116 0.5786714434021809 2.5459348644566675 1.8508121101441584 0.8186540272344984 0.2959289197143789 1.0 0.0181053013145446 0.0666692325567911 0.2903927816552063 0.6384371778956772 +Tyrosine-specific protein phosphatases domain [IPR000387] 4 9 2.1652127444983105 0.0303713967977334 2.7063106796116503 7.213592233009709 -0.3132851926661954 0.5285529785740709 1.7372724354944058 2.1390973753662776 0.9021701078616204 0.297631084722613 1.0 1.0 0.0803922289273931 0.0307995556081591 0.2142435661583282 +Proteasome component (PCI) domain [IPR000717] 12 19 2.133669470882437 0.0328698468117165 6.577669902912621 18.740291262135923 0.0656253515457994 0.631967867263698 3.806137915628319 1.385790550244499 0.8221014102906427 0.3084914974953499 1.0 1.0 0.1993869387044997 0.4327587673805496 0.0006386483653524 +Chromo domain [IPR023780] 4 9 2.0178964965447124 0.0436020420106002 3.429611650485437 7.344660194174757 -0.2446353400091022 0.5266915062089434 2.0258994992900043 1.637736310990822 0.9083740295568274 0.3054198908813051 1.0 1.0 0.1837383274168749 0.0914454637274335 0.0794376465838621 +WW domain [IPR001202] 4 14 1.998641518619385 0.0456471547548029 4.441747572815534 12.67233009708738 -0.1147336416820729 0.5822943336583314 2.9377034908850463 2.6762006483919305 0.8657860707300005 0.3029321466270899 1.0 1.0 0.0614247268920475 0.0185450998789275 0.0516637732040453 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 3 9 1.9957725535830555 0.0459586855919758 2.878640776699029 6.735436893203883 -0.1009242226376213 0.5398631989476717 1.7790119700005456 1.6967720791950751 0.9747821830158722 0.3245983921794569 1.0 1.0 1.0 0.0062969264366488 0.00630824692371 +Importin-beta, N-terminal domain [IPR001494] 7 13 1.9720587095189377 0.0486029048224789 6.385922330097087 13.28883495145631 0.1695856896111973 0.5104356360219653 3.297409379395681 0.8134617396566306 1.1027535719761996 0.3475482514742156 1.0 1.0 1.0 1.0 0.0468003866103798 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b73a02c679690cbf3f2b62a73e74b2403188954f --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2802, + "title": "Average number of proteins per term", + "value": 2.2455389007851534 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2f19221efd5fc77ac15f00e5b02cf5b1eab1be6a --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..60396ab1d22e14e4265a7b338a1a50f94d87928b --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,332 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.8626434325729313 2.66950152293713 0.0075963928629572 0.999999999474331 0.0664679289640101 7 P25788,P25789,P60900,P25786,P28066 5 +Cold-shock protein, DNA-binding [IPR002059] 0.947269130657141 2.38313974339129 0.0171656767355035 1.0 0.0914414947012943 4 P67809 1 +Cold shock domain [IPR011129] 0.947269130657141 2.38313974339129 0.0171656767355035 1.0 0.0914414947012943 4 P67809 1 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8964725207226569 2.343781263498936 0.0190893630126129 1.0 0.0946697259492771 5 P48735 1 +SPRY domain [IPR003877] 0.6789944767728417 2.281382243499555 0.0225258378334338 1.0 0.1044990026643736 11 Q9UBL3 1 +B30.2/SPRY domain [IPR001870] 0.6789944767728417 2.281382243499555 0.0225258378334338 1.0 0.1044990026643736 11 Q9UBL3 1 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.9009924870531792 2.199618033309891 0.0278340066416746 1.0 0.1172572733136019 4 Q15435,P39687 2 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.6823356117267941 2.1652127444983105 0.0303713967977334 1.0 0.1230389622634987 9 Q9UNI6,O60942,P51452,Q13614 4 +Proteasome component (PCI) domain [IPR000717] 0.5579736427962465 2.133669470882437 0.0328698468117165 1.0 0.1291743489010235 19 Q14152,Q9UNS2,P60228,Q9Y262,Q9UBQ5,Q9UNM6,O00232,P61201,Q15008,Q9UBW8,P48556,O43242 12 +Dual specificity protein phosphatase domain [IPR020422] 0.8683332197874098 2.068006457167298 0.0386394159113974 1.0 0.1420913770763978 4 Q9UNI6,O60942 2 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.8683332197874098 2.068006457167298 0.0386394159113974 1.0 0.1420913770763978 4 Q9UNI6,O60942 2 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.8620286465945664 2.0424063609363454 0.0411112393065855 1.0 0.1474951248873914 4 Q13596,Q9UNH7,O60749 3 +Chromo domain [IPR023780] 0.6533619044264619 2.0178964965447124 0.0436020420106002 1.0 0.1530988993906039 9 Q12873,Q9HC52,O14646,P83916 4 +WW domain [IPR001202] 0.5833657028554243 1.998641518619385 0.0456471547548029 1.0 0.1579053427443924 14 Q13526,P46934,O95817,Q96PU5 4 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.649049299735715 1.9957725535830553 0.0459586855919758 1.0 0.1580777408384541 9 Q13535,P42356,Q96Q15 3 +Importin-beta, N-terminal domain [IPR001494] 0.5935939452971277 1.9720587095189377 0.0486029048224789 1.0 0.1634878022960217 13 Q92973,O15397,O95373,O43592,Q9UIA9,P55060,Q9HAV4 7 +Phosphoribosyltransferase domain [IPR000836] 0.704183735412646 1.9509543215735 0.0510624798031624 1.0 0.1680548606529342 7 P11172,Q06203,O60256,P11908,P60891 5 +Phox homology [IPR001683] 0.6018535427301961 1.9374743354380417 0.0526873876333042 1.0 0.1710661183644479 12 Q96L92,Q15036,O60493,Q9UNH7,O60749,Q13596,A1X283,Q9Y5X3 8 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9488752556237235 1.916855462222521 0.0552562965925722 1.0 0.1755421123042941 2 P98179 1 +OTU domain [IPR003323] 0.9421560035056992 1.889120796120471 0.0588756444610134 1.0 0.1839125482494534 2 Q01804 1 +W2 domain [IPR003307] 0.6813926272673962 1.842934659109641 0.0653385511413202 1.0 0.1972829960107536 7 Q9Y6E2,Q04637,P55010,Q13144,Q7L1Q6,P78344 6 +Rab-GTPase-TBC domain [IPR000195] 0.6798900747189116 1.835775342664384 0.0663908896462717 1.0 0.198143909460619 7 O60343,Q66K14,Q8TC07,Q9NVG8 4 +Cold-shock (CSD) domain [IPR019844] 0.9475548411519756 1.829015911284844 0.0673972246681144 1.0 0.199626874756931 3 P67809 1 +NudC N-terminal domain [IPR025934] 0.9202453987730076 1.798384099745095 0.0721161607053892 1.0 0.2089653384658746 2 Q8IVD9 1 +14-3-3 domain [IPR023410] 0.7130739982451005 1.7945239204549257 0.072729584127241 1.0 0.2098746598604834 6 Q04917,P61981,P27348,P63104,P31946 5 +HECT domain [IPR000569] 0.5600663048015376 1.7813876417148788 0.0748491457311173 1.0 0.2124896720755732 13 Q8IYU2,Q96J02,Q15386,Q7Z6Z7,P46934,Q96PU5 6 +MPN domain [IPR037518] 0.6058323990012461 1.7713845473050054 0.0764967764730526 1.0 0.215424370925418 9 Q7L5N1,Q92905,P51665 3 +Protein kinase domain [IPR000719] 0.3452487608426723 1.7556023395928937 0.0791563324765738 1.0 0.2202542637530882 74 Q8IV63,Q99570,P36507,P33981,Q13043,P24941,P51617,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q9P289,Q14012,P17612,Q96KB5,P19525,P31751,P49841,O75116,Q13177,Q13546,Q99986,Q00535,P41240,Q9UHY1,Q96SB4,P10398,Q9NYV4,O14965,P19784,O95747,P06493 35 +CRK, C-terminal SH3 domain [IPR035458] 0.9050540461583448 1.735232745730525 0.0826995886217194 1.0 0.2267360541272582 2 P46108 1 +CRK, N-terminal SH3 domain [IPR035457] 0.9050540461583448 1.735232745730525 0.0826995886217194 1.0 0.2267360541272582 2 P46108 1 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.7872197831934674 1.7342089810589203 0.0828810100148975 1.0 0.2269963228878997 4 Q86TI2,Q4J6C6 2 +Glutamine amidotransferase [IPR017926] 0.7842725127543229 1.7219137275650744 0.0850851478522898 1.0 0.22963850972653 4 P49915,P17812 2 +Chaperone DnaJ, C-terminal [IPR002939] 0.744871828250133 1.7081113656662814 0.0876156803865466 1.0 0.2340315886016241 5 P25685,O60884 2 +Phospholipase D/Transphosphatidylase [IPR001736] 0.894829097283093 1.6926312374205608 0.0905256813200918 1.0 0.2366165662862848 2 Q8N2A8 1 +Sec23, C-terminal [IPR037550] 0.8916155419222944 1.6792279806384909 0.0931076207546035 1.0 0.2408934010659272 2 Q15437 1 +Sorting nexin, N-terminal [IPR005329] 0.890739117732984 1.6755714430340978 0.0938221662930349 1.0 0.2425181826135461 2 Q13596 1 +Actin-depolymerising factor homology domain [IPR002108] 0.5866538745447939 1.6703480875264798 0.0948505141756943 1.0 0.2444731213828521 9 P60981,Q9Y281,P23528,P60983,Q14019,Q6IBS0 6 +AP complex, mu/sigma subunit [IPR022775] 0.681281892824366 1.6498303142019035 0.0989776467367604 1.0 0.2512095707938431 6 P61923,Q92572 2 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.6410177932932837 1.6490469955830227 0.0991380072177339 1.0 0.2513888653611678 7 Q92905,P51665 2 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.6377848515603819 1.6333950274676114 0.1023859421785342 1.0 0.2556910962426497 7 Q9C0C9,P49427,Q16763,P68036 4 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.7617655656240923 1.6276957311914342 0.1035894187151611 1.0 0.2574803150579453 4 P11908,Q14558,P60891 3 +Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678] 0.8761320479111895 1.614566149902541 0.1064046808448018 1.0 0.2575956687501055 2 O95747 1 +Heat shock chaperonin-binding [IPR006636] 0.722177322197672 1.6099211513905398 0.1074150707918701 1.0 0.2596868234329769 5 P54727,P31948,P54725 3 +CS domain [IPR007052] 0.5615003217988339 1.5927726385286718 0.111211205365882 1.0 0.2654644309860519 10 Q9HB71,Q9Y266,O94966,Q8IVD9,Q96RS6 5 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5355917209802724 1.5674517465447495 0.1170091366857051 1.0 0.2734442043313976 12 Q96AY3,Q5T1M5 2 +TOG domain [IPR034085] 0.6229530812768875 1.5613762196709144 0.1184350093636261 1.0 0.2756681488540461 7 O75122,Q7Z460,Q86Y56 3 +Rpn11/EIF3F, C-terminal [IPR024969] 0.7455548424259479 1.559514806239195 0.1188745829533359 1.0 0.2756681488540461 4 P51665 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.2766741200649723 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.2766741200649723 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +CAP Gly-rich domain [IPR000938] 0.7445191464484158 1.5551507369706816 0.1199101737047305 1.0 0.2766741200649723 4 Q15813,Q99426,Q14203 3 +Ubiquitin-associated domain [IPR015940] 0.4773766886479755 1.5504177134748156 0.121041289703208 1.0 0.2777704289503594 17 Q92995,P54727,Q5T6F2,Q14157,P54725,Q7Z6Z7,Q9UPU5,Q9BSL1,Q04323 9 +FATC domain [IPR003152] 0.7034801094571327 1.528588711143274 0.1263664363242014 1.0 0.2844006060886846 5 P42345,Q13535,Q96Q15 3 +PIK-related kinase [IPR014009] 0.7034801094571327 1.528588711143274 0.1263664363242014 1.0 0.2844006060886846 5 P42345,Q13535,Q96Q15 3 +Exportin-1/Importin-beta-like [IPR013598] 0.7375036539023789 1.5255668481357134 0.1271177736289237 1.0 0.2852228674649983 4 O43592,Q9Y5L0,Q9HAV4 3 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.8533450189891996 1.5192168580257788 0.1287079193164748 1.0 0.2866769395268382 2 Q04760 1 +BZW1/2, W2 domain [IPR043510] 0.8501314636283952 1.5057588290684094 0.1321290958322616 1.0 0.2912927401534435 2 Q7L1Q6 1 +EB1, C-terminal [IPR004953] 0.8498393222319669 1.5045352885462846 0.1324435942025292 1.0 0.2912927401534435 2 Q15555 1 +Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.847794332456915 1.495970174086595 0.1346614277435422 1.0 0.2933163312361659 2 Q9UN37 1 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.6959064327485442 1.495548160898278 0.1347714406266891 1.0 0.2933163312361659 5 P62195,P62191,P17980,P62333 4 +Glutathione S-transferase, C-terminal [IPR004046] 0.5420747821447787 1.487046681332164 0.1370024821987665 1.0 0.2961583724782697 10 P26641,P26640,P28161,P21266,P78417,Q13155,O43708 7 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.2961583724782697 6 Q15437,Q15436,O95486 3 +Sec23/Sec24, trunk domain [IPR006896] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.2961583724782697 6 Q15437,Q15436,O95486 3 +Sec23/Sec24, helical domain [IPR006900] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.2961583724782697 6 Q15437,Q15436,O95486 3 +Sec23/Sec24 beta-sandwich [IPR012990] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.2961583724782697 6 Q15437,Q15436,O95486 3 +Gelsolin-like domain [IPR007123] 0.5690064942917614 1.4806606315008966 0.1386970297099887 1.0 0.2982571582865606 8 Q15436,Q15437,O95486 3 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.5396141993887872 1.4736099568836247 0.140586638955859 1.0 0.3007051621025319 10 P53618,Q9UBF2,Q9Y678,O00203,O94973,O14617 6 +La protein, xRRM domain [IPR014886] 0.8422436459246347 1.472719834291217 0.1408265961329684 1.0 0.3007956947104672 2 P05455 1 +High mobility group box domain [IPR009071] 0.5151037785743393 1.4511066954274452 0.146750152427165 1.0 0.306632309545799 12 P09429,O15347,Q08945,O96028,Q00059 5 +MIT domain [IPR007330] 0.848042080654593 1.4432803351777748 0.1489415170388304 1.0 0.3091363931428169 3 Q9UN37,Q8N0X7 2 +VHS domain [IPR002014] 0.6782278912158738 1.4182520601170732 0.1561171875456311 1.0 0.3179518596373687 5 Q9UJY5 1 +F-BAR domain [IPR031160] 0.8247151621384778 1.399300945126509 0.1617227563488679 1.0 0.3231374843706935 2 Q9UNF0 1 +FCH domain [IPR001060] 0.8247151621384778 1.399300945126509 0.1617227563488679 1.0 0.3231374843706935 2 Q9UNF0 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.82267017236343 1.390738250516835 0.1643048140249112 1.0 0.3251958638707826 2 O43924 1 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.5510067159950156 1.3871352279992382 0.1654005317426361 1.0 0.3259694471003095 8 Q9UHY1,Q13546,P10398 3 +Gamma-glutamyl cyclotransferase-like [IPR013024] 0.821793748174124 1.3870688446519144 0.1654207710950723 1.0 0.3259694471003095 2 Q8WUX2 1 +Nucleoside phosphorylase domain [IPR000845] 0.8215016067776933 1.3858457551124714 0.1657940075434263 1.0 0.3260033748327583 2 Q13126 1 +XPC-binding domain [IPR015360] 0.8191644756061984 1.376061922443628 0.1688024629957465 1.0 0.3276492919647015 2 P54725 1 +RAD23A/RAD23B, UBA1 domain [IPR041811] 0.8191644756061984 1.376061922443628 0.1688024629957465 1.0 0.3276492919647015 2 P54725 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.8179959100204623 1.3711706390807643 0.1703217686186604 1.0 0.3293592792750079 2 Q4J6C6 1 +Zinc finger, LIM-type [IPR001781] 0.5296337467782349 1.3657864806756512 0.172005990945977 1.0 0.3311810857785321 9 Q9UGI8,Q15942,Q16527,Q96HC4,Q9UHB6,Q13642,O00151 7 +CTP synthase, N-terminal [IPR017456] 0.8141980718667869 1.3552772770226205 0.175329231836415 1.0 0.3357411058694758 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.8141980718667869 1.3552772770226205 0.175329231836415 1.0 0.3357411058694758 2 P17812 1 +PIK-related kinase, FAT [IPR003151] 0.696922683242485 1.3538439995267426 0.1757861528381932 1.0 0.3357411058694758 4 P42345,Q13535 2 +BSD domain [IPR005607] 0.8127373648846175 1.3491659369210782 0.1772836731467508 1.0 0.3367788828184379 2 Q9NW68 1 +U-box domain [IPR003613] 0.575277748947935 1.3280228586670184 0.184170555523532 1.0 0.3438013967867666 7 P19474 1 +Chromo/chromo shadow domain [IPR000953] 0.5025047102912694 1.3233074788777068 0.1857331455863868 1.0 0.3462570019514677 11 Q12873,Q9HC52,O14646,P83916 4 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.8109457151107637 1.2986455781918953 0.1940655886647841 1.0 0.3544796476132498 3 O60884 1 +La-type HTH domain [IPR006630] 0.6499999999999894 1.294505377518815 0.1954909130226128 1.0 0.3560681352887986 5 Q6PKG0,Q4G0J3,Q92615,P05455 4 +Intermediate filament head, DNA-binding domain [IPR006821] 0.6799181525869693 1.281736940850263 0.1999349416147238 1.0 0.3607052732312051 4 Q16352,P07197,P07196 3 +Death domain [IPR000488] 0.6796116747363194 1.2804373743585158 0.2003913566495851 1.0 0.3607052732312051 4 Q12955,Q13546 2 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.7952088810984553 1.2759177142750913 0.2019846084059482 1.0 0.3622908579143901 2 O60841 1 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.5975503512403068 1.2628809171038002 0.2066319789073429 1.0 0.3666768872060639 6 Q04637,Q9HCG8,Q53EL6,P78344 4 +Ribosomal protein S5, C-terminal [IPR005324] 0.7890739117732978 1.2503309987817213 0.2111786590968121 1.0 0.3693649205925515 2 P15880 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.7890739117732978 1.2503309987817213 0.2111786590968121 1.0 0.3693649205925515 2 P15880 1 +Prenylcysteine lyase [IPR010795] 0.7864446392053814 1.2393753047523763 0.2152065425299598 1.0 0.3742376296173149 2 Q9UHG3 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.7943083237754776 1.2338942449288812 0.2172423143248831 1.0 0.3759808305980992 3 Q9BYT8 1 +Exportin-2, central domain [IPR013713] 0.7916423144360104 1.2235325709649765 0.2211286099074589 1.0 0.3798910882652974 3 O95373,O15397 2 +Translation initiation factor IF2/IF5 domain [IPR002735] 0.7730061349693375 1.1834914083832058 0.236614449545458 1.0 0.4010851104817746 2 P55010 1 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.7748944341268184 1.1585652493330658 0.246633440644262 1.0 0.4125772541404312 3 Q4G0X4 1 +tRNA synthetases class I, catalytic domain [IPR032678] 0.7662868828512982 1.1556317458136716 0.2478318171770002 1.0 0.4140875084853635 2 P49589 1 +Domain of unknown function DUF1747 [IPR013719] 0.7639497516798209 1.1459562475002838 0.2518132559068999 1.0 0.4189939670150439 2 Q08945 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846] 0.7630429097003162 1.1127562212358917 0.2658131422417042 1.0 0.4337430590622931 3 Q96G03 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845] 0.7630429097003162 1.1127562212358917 0.2658131422417042 1.0 0.4337430590622931 3 Q96G03 1 +Coatomer, WD associated region [IPR006692] 0.7557697925796057 1.112158705042861 0.2660699195570382 1.0 0.4337430590622931 2 P35606 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.6360447213130983 1.0961241231087908 0.2730244591439146 1.0 0.4404228753720487 4 Q96G03 1 +GNAT domain [IPR000182] 0.6041587159442166 1.093708844269139 0.2740826941000813 1.0 0.4418755517079562 5 Q86UY6,Q9H9T3 2 +SNF2, N-terminal [IPR000330] 0.4025418209856051 1.083195833719691 0.2787215086142924 1.0 0.4454166011017239 18 O14981,Q9H4L7,Q14527,Q12873,O14646,Q9Y620 6 +Zinc finger, FYVE-related [IPR017455] 0.6003265262464051 1.0769929805234104 0.281483401656398 1.0 0.4478798929251717 5 Q15075,Q96T51,O14964 3 +FYVE zinc finger [IPR000306] 0.6003265262464051 1.0769929805234104 0.281483401656398 1.0 0.4478798929251717 5 Q15075,Q96T51,O14964 3 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.7449605609114869 1.0676769366407295 0.2856662654088406 1.0 0.4524798618855689 2 Q9Y678 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.7449605609114869 1.0676769366407295 0.2856662654088406 1.0 0.4524798618855689 2 Q9Y678 1 +Ubiquitin system component CUE [IPR003892] 0.7443765655763135 1.0409795070361585 0.2978850593433384 1.0 0.4640541013096129 3 Q9H4L7 1 +TATA-binding protein interacting (TIP20) [IPR013932] 0.7382413087934604 1.040143632087027 0.2982731750387626 1.0 0.4640541013096129 2 Q86VP6 1 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.7364884604148398 1.032977305738694 0.3016145191778401 1.0 0.4676944564119026 2 O95336 1 +BAG domain [IPR003103] 0.6208125992558717 1.032103941139496 0.3020234277896163 1.0 0.4680694937314739 4 O95817 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.7402104032729456 1.0250348845081183 0.3053467278652069 1.0 0.4701162800793916 3 Q06210,Q06203 2 +FAD dependent oxidoreductase [IPR006076] 0.6156101580286133 1.010320817932456 0.3123416103688226 1.0 0.4756419523116526 4 Q9H9P8 1 +BTB/POZ domain [IPR000210] 0.5412309128303967 1.0019815049645195 0.3163525255431261 1.0 0.4804443233451704 6 Q4G0X4 1 +CSN8/PSMD8/EIF3K [IPR033464] 0.7324116857383239 0.9952738282288124 0.3196031030855146 1.0 0.4830221637309476 3 P48556 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.5372152898869127 0.9835276621430789 0.3253478077673417 1.0 0.4893314854342949 6 P09960,Q6P179 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.5372152898869127 0.9835276621430789 0.3253478077673417 1.0 0.4893314854342949 6 P09960,Q6P179 2 +Mu homology domain [IPR028565] 0.6082252425887235 0.9794860680965576 0.3273398690825169 1.0 0.4903264044434237 4 Q9BXS5 1 +CP2 transcription factor [IPR007604] 0.7230499561788082 0.9782833162912268 0.327934219103132 1.0 0.4903264044434237 2 Q12800 1 +SAM domain [IPR041418] 0.7230499561788082 0.9782833162912268 0.327934219103132 1.0 0.4903264044434237 2 Q12800 1 +Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211] 0.720712825007302 0.9688197135901012 0.332635148918571 1.0 0.4952410665620808 2 P09960 1 +EH domain [IPR000261] 0.5306366610121646 0.9533700475719116 0.3404026118493224 1.0 0.502798164682025 6 Q9H223,Q9UBC2,P42566,Q9H4M9 4 +CLASP N-terminal domain [IPR024395] 0.7164635234903856 0.9348108144041144 0.3498858053478955 1.0 0.5093275893240324 3 O75122 1 +ERM family, FERM domain C-lobe [IPR041789] 0.7142022209234368 0.9262861120278209 0.3542973113615595 1.0 0.5127794764644059 3 P15311,P26038 2 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.7136905815697505 0.9243591255695984 0.3552993684872438 1.0 0.51316950025838 3 P42356 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.7081507449605611 0.9182299182832996 0.3584985085301424 1.0 0.5158235752586956 2 P62495 1 +eRF1 domain 2 [IPR005141] 0.7081507449605611 0.9182299182832996 0.3584985085301424 1.0 0.5158235752586956 2 P62495 1 +eRF1 domain 3 [IPR005142] 0.7081507449605611 0.9182299182832996 0.3584985085301424 1.0 0.5158235752586956 2 P62495 1 +GINS subunit, domain A [IPR021151] 0.7109866417110147 0.9141865706536288 0.3606188194419131 1.0 0.5181815036288413 3 Q9BRT9 1 +Domain of unknown function DUF3517 [IPR021905] 0.7026000584282796 0.8960379920148265 0.3702324725919559 1.0 0.5260605416849191 2 Q93008 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.5175234492219747 0.8935830775757075 0.3715450038878261 1.0 0.5272546743613797 6 Q9HCE1 1 +Vps4 oligomerisation, C-terminal [IPR015415] 0.7054478812774374 0.8934104745117466 0.3716373953831995 1.0 0.5272546743613797 3 Q9UN37 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.7002629272568077 0.8867261222231335 0.3752263708922703 1.0 0.5310021672930006 2 P29692 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.7002629272568077 0.8867261222231335 0.3752263708922703 1.0 0.5310021672930006 2 P29692 1 +Glutathione S-transferase, N-terminal [IPR004045] 0.4530732803403652 0.8784039125942773 0.3797245618400811 1.0 0.5365548271688891 8 P28161 1 +Kinesin-associated [IPR032405] 0.5837108968531493 0.8780376547940463 0.3799232845094131 1.0 0.536565041933153 4 Q9NQT8 1 +Staufen, C-terminal [IPR032478] 0.6992986557568657 0.8704467964729204 0.3840562823693292 1.0 0.541038563699779 3 Q9NUL3,O95793 2 +HR1 rho-binding domain [IPR011072] 0.5809230874378075 0.8666068278017834 0.3861574711965079 1.0 0.5426345207084329 4 O75116,Q16512 2 +Zinc finger, CCHC-type [IPR001878] 0.4338858476485621 0.852356407008576 0.3940163075333367 1.0 0.5500915265114148 9 Q5TAX3 1 +Nucleoside diphosphate kinase-like domain [IPR034907] 0.6925859678706816 0.8455107443146228 0.3978257363552182 1.0 0.5514250871337943 3 P15531 1 +FERM central domain [IPR019748] 0.408318378230755 0.8446307213652192 0.3983170508061384 1.0 0.5514250871337943 12 P26038,Q96AC1,P15311,Q9Y4F1,Q9Y2J2 5 +Band 4.1 domain [IPR019749] 0.408318378230755 0.8446307213652192 0.3983170508061384 1.0 0.5514250871337943 12 P26038,Q96AC1,P15311,Q9Y4F1,Q9Y2J2 5 +ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.6888694127957935 0.8416237518396167 0.39999858996393 1.0 0.5532063420922665 2 P60842 1 +Nucleotidyl transferase domain [IPR005835] 0.6912266856032012 0.8404789878992673 0.400639877965923 1.0 0.5538199003751931 3 Q96IJ6 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.5690965509285003 3 Q9UL46,P61289 2 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.5690965509285003 3 Q9UL46,P61289 2 +TGS [IPR004095] 0.4688109910441485 0.8091083722087532 0.418452812960852 1.0 0.5694535123440055 7 Q9NTK5,P55039,A2RTX5 3 +YTH domain [IPR007275] 0.5654928307301886 0.8038183000714654 0.4215019193658857 1.0 0.5719362605632988 4 Q9Y5A9,Q7Z739 2 +DnaJ domain [IPR001623] 0.3571685554712804 0.7880868377560316 0.4306459136261407 1.0 0.5804411925199411 18 O75165,Q99543,O60884,O75937,P25685,Q99615,P31689,Q8WXX5,O75190 9 +MoaB/Mog domain [IPR001453] 0.6722173531989488 0.7766818707411366 0.4373464854517577 1.0 0.5829899392178045 2 Q9NQX3 1 +MCM N-terminal domain [IPR027925] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.583442621817585 6 P33992,P25205,P33991,P49736 4 +MCM domain [IPR001208] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.583442621817585 6 P33992,P25205,P33991,P49736 4 +MCM, AAA-lid domain [IPR041562] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.583442621817585 6 P33992,P25205,P33991,P49736 4 +MCM OB domain [IPR033762] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.583442621817585 6 P33992,P25205,P33991,P49736 4 +Amidohydrolase-related [IPR006680] 0.5557431706728047 0.7646198332271777 0.4444979555434001 1.0 0.5880468703647814 4 Q16555,Q14195 2 +PIN domain [IPR002716] 0.6675430908559914 0.7586858370806795 0.4480405111276146 1.0 0.5894891635772848 2 Q9Y2L1 1 +Putative WW-binding domain and destruction box [IPR033461] 0.6675430908559825 0.7586858370806461 0.4480405111276346 1.0 0.5894891635772848 2 Q8TF05 1 +Sterile alpha motif domain [IPR001660] 0.4872851707888115 0.7579794974313776 0.4484632567501028 1.0 0.5894891635772848 6 Q6SZW1,Q9Y6Y8 2 +ABC-transporter extension domain [IPR032781] 0.6660823838737968 0.7530846689937027 0.45139903647223 1.0 0.5926992034654116 2 Q9UG63 1 +EH domain-containing protein, N-terminal [IPR031692] 0.6646216768916178 0.7474945249885933 0.4547651064549751 1.0 0.5954880893147101 2 Q9H223 1 +Domain of unknown function DUF5600 [IPR040990] 0.6646216768916178 0.7474945249885933 0.4547651064549751 1.0 0.5954880893147101 2 Q9H223 1 +PurM-like, N-terminal domain [IPR016188] 0.6617002629272608 0.736347930712981 0.4615189838644193 1.0 0.5992475406803073 2 P49903 1 +HDGF-related, PWWP domain [IPR035496] 0.6616163130757086 0.7325573976366719 0.4638284229529847 1.0 0.6007419165648543 3 P51858 1 +Ubiquitin-like domain [IPR000626] 0.3607635874763584 0.7244385494548637 0.4687965404956324 1.0 0.6039392673419597 15 Q15813,Q15370,Q8NCF5,P54725 4 +Inositol polyphosphate-related phosphatase [IPR000300] 0.6581945661700446 0.7230328122565075 0.4696597255337713 1.0 0.6044954299244958 2 Q01968 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.6579024247735945 0.7219262760062913 0.4703398053698191 1.0 0.6050928074592439 2 O94979 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.376933499734938 0.7183502182326875 0.4725413734198069 1.0 0.6059775415662696 13 P26641,O00299,P26640,P28161,P21266,P78417 6 +Kinesin-like [IPR022164] 0.5413621748026983 0.7075913722504336 0.4791990522301645 1.0 0.6122734812352582 4 Q9Y3P9,Q9NQT8,Q12756 3 +Importin-alpha, importin-beta-binding domain [IPR002652] 0.5362987791345379 0.687763301837554 0.4916018495527687 1.0 0.6224439143456204 4 P52294,O60684 2 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.6441717791411135 0.6704789052708523 0.5025525493844227 1.0 0.6315506025369825 2 P31751 1 +B-box, C-terminal [IPR003649] 0.527107121800594 0.6521403253180504 0.5143106520805796 1.0 0.6410580280826441 4 O15344,Q13263 2 +Dynamin stalk domain [IPR000375] 0.6380368098159555 0.6478680578571997 0.5170702919557322 1.0 0.6419277616570498 2 P50570 1 +GTPase effector domain [IPR020850] 0.6380368098159555 0.6478680578571997 0.5170702919557322 1.0 0.6419277616570498 2 P50570 1 +Dynamin GTPase effector [IPR003130] 0.6380368098159555 0.6478680578571997 0.5170702919557322 1.0 0.6419277616570498 2 P50570 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6371603856266477 0.6446580704759908 0.5191487939295145 1.0 0.6439375478488268 2 Q13310 1 +Peptidase S8/S53 domain [IPR000209] 0.6330704060765482 0.6297467873825391 0.5288602658390618 1.0 0.6522299581342654 2 O14773 1 +Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854] 0.6309175920514265 0.6248543180277393 0.5320666767243285 1.0 0.6533297013244188 3 Q6BDS2,Q96RL7 2 +Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.4280610953942207 0.6205618963125222 0.5348879168806471 1.0 0.6556237721345464 7 Q9BRF8 1 +GRAM domain [IPR004182] 0.5182489713200626 0.6183013808286791 0.5363766918538766 1.0 0.6560272198834289 4 Q13614 1 +PPM-type phosphatase domain [IPR001932] 0.6285797779076577 0.6168624287671912 0.5373254702724712 1.0 0.6560287440973701 3 O15355,Q9H0C8 2 +FKBP3, basic tilted helix bundle domain [IPR041200] 0.6257668711656599 0.6034104489109969 0.5462356728195314 1.0 0.659258348496132 2 Q00688 1 +Zinc finger, RING-type [IPR001841] 0.2725305261303019 0.601512417522969 0.5474987436209771 1.0 0.6595406189277634 33 P19474,O96028,P98170 3 +Putative RNA methylase domain [IPR000241] 0.6237218813906101 0.5961055842663951 0.5511046938692572 1.0 0.6630293483132926 2 Q7Z4G4 1 +Calponin homology domain [IPR001715] 0.2915364282419312 0.5916080644065866 0.554113072402806 1.0 0.6649356868833672 28 Q15555,Q15417,Q86VS8,Q99439 4 +ROCK, Rho binding domain [IPR015008] 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.6654663253429075 2 O75116 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6201052016364628 0.5881711420964919 0.5564174251842267 1.0 0.6654663253429075 3 Q13310,P11940 2 +Zinc finger, UBR-type [IPR003126] 0.6201052016364607 0.5881711420964852 0.5564174251842311 1.0 0.6654663253429075 3 Q5T4S7,Q8N806 2 +C2 domain [IPR000008] 0.3241456225614389 0.5844501444237382 0.558917498374345 1.0 0.6667036315218879 18 Q86YQ8,Q96J02,Q96PU5 3 +NAD(P)-binding domain [IPR016040] 0.6187554776511923 0.5784962922569594 0.5629290999257837 1.0 0.6675105112111916 2 Q8NBZ7 1 +FF domain [IPR002713] 0.6178790534618921 0.5754084457164985 0.5650150935492673 1.0 0.6678891067917804 2 O75400 1 +Domain of unknown function DUF4749 [IPR031847] 0.6172947706690213 0.573353214836315 0.5664055610922141 1.0 0.6678891067917804 2 Q96HC4 1 +26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.617002629272577 0.5723266038939852 0.5671007295113126 1.0 0.6679345288317352 2 Q15008 1 +PWWP domain [IPR000313] 0.3773228571160504 0.5653581894330122 0.5718301570198938 1.0 0.6723743600376594 9 O96028,P51858 2 +THIF-type NAD/FAD binding fold [IPR000594] 0.377027978159468 0.5639354581547046 0.5727980575372651 1.0 0.673229931719554 9 Q9GZZ9,Q9UBE0 2 +Glutaredoxin, PICOT-like [IPR033658] 0.6082383873794988 0.5418473067932356 0.5879236990924857 1.0 0.6884087776252171 2 O76003 1 +von Willebrand factor, type A [IPR002035] 0.4019875662258613 0.5067644647957467 0.6123200924933117 1.0 0.7095619930381553 7 Q86YQ8 1 +Elp3/MiaB/NifB [IPR006638] 0.4855291610247723 0.4982614811953553 0.6182997534207095 1.0 0.7123061465628662 4 Q9H9T3 1 +Radical SAM [IPR007197] 0.4855291610247723 0.4982614811953553 0.6182997534207095 1.0 0.7123061465628662 4 Q9H9T3 1 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.5918784691790926 0.4867101565329041 0.626463746645054 1.0 0.716762522702916 2 P52701 1 +FERM domain [IPR000299] 0.345124172203739 0.4778409699374566 0.6327633984441172 1.0 0.7227774245200045 11 P15311,P26038,Q9Y4F1,Q9Y2J2 4 +KOW [IPR005824] 0.5859398944752615 0.4774936589113347 0.6330106351791902 1.0 0.7227774245200045 3 P62701 1 +NADP-dependent oxidoreductase domain [IPR023210] 0.4790996784566081 0.4757327578998198 0.6342647802082824 1.0 0.7239144253130783 4 P15121,P48507,P14550 3 +Survival motor neuron [IPR010304] 0.5883727724218575 0.4752131419098393 0.6346350609330549 1.0 0.7240421175628745 2 O75940 1 +Kinesin-like KIF1-type [IPR022140] 0.5849714455366418 0.474485794145162 0.6351535258385033 1.0 0.7242526370407378 3 Q9NQT8 1 +UBX domain [IPR001012] 0.4532890676365354 0.4739388811999559 0.6355434918585798 1.0 0.7242526370407378 5 O94888,Q9UNN5 2 +FERM, C-terminal PH-like domain [IPR018980] 0.3553730296045014 0.4624028847590392 0.6437924309900269 1.0 0.7321048667346004 9 P15311,P26038,Q9Y4F1,Q9Y2J2 4 +FERM, N-terminal [IPR018979] 0.3553730296045014 0.4624028847590392 0.6437924309900269 1.0 0.7321048667346004 9 P15311,P26038,Q9Y4F1,Q9Y2J2 4 +Ariadne domain [IPR045840] 0.5839906514753227 0.4610083233918058 0.6447926334954455 1.0 0.7329448109753501 2 O95376 1 +C-CAP/cofactor C-like domain [IPR017901] 0.5797779076563303 0.4584884674652853 0.6466015460624701 1.0 0.7342243898157897 3 Q15814,Q01518 2 +CARP motif [IPR006599] 0.5797779076563303 0.4584884674652853 0.6466015460624701 1.0 0.7342243898157897 3 Q15814,Q01518 2 +Aminotransferase class V domain [IPR000192] 0.5831142272860164 0.4581899659675631 0.6468159680925052 1.0 0.7342243898157897 2 Q96EN8 1 +PurM-like, C-terminal domain [IPR010918] 0.5796117739373133 0.4579804885673872 0.6469664591203372 1.0 0.7342243898157897 3 P49903 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7389403695085776 2 Q16706 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7389403695085776 2 Q16706 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7389403695085776 2 Q16706 1 +Endonuclease/exonuclease/phosphatase [IPR005135] 0.4452610561286771 0.4451500281106542 0.6562113370666074 1.0 0.7423197757581956 5 Q01968,P27695 2 +Mib-herc2 [IPR010606] 0.5790242477359102 0.4451392032304994 0.6562191593693971 1.0 0.7423197757581956 2 Q9ULT8 1 +Sec24-like, trunk domain [IPR041742] 0.4699303495105313 0.4442909591511312 0.656832236832646 1.0 0.7427134493967208 4 O95486 1 +Pre-PUA domain [IPR041366] 0.577855682150171 0.4414415249317496 0.6588933857955328 1.0 0.7444432528222155 2 Q9ULC4 1 +SUI1 domain [IPR001950] 0.577855682150169 0.4414415249317441 0.6588933857955368 1.0 0.7444432528222155 2 O43583 1 +Rap/Ran-GAP domain [IPR000331] 0.5769792579608594 0.4386774518267062 0.660895267456153 1.0 0.7455026326135832 2 Q96FS4 1 +GHMP kinase, C-terminal domain [IPR013750] 0.5749342681858133 0.4322588137452762 0.6655533177433182 1.0 0.749248853482032 2 P51570 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.5717207128250144 0.4222607334351904 0.6728347158481678 1.0 0.756365081691834 2 P04066 1 +CRA domain [IPR013144] 0.5714285714285823 0.4213572287400261 0.6734942465457265 1.0 0.756365081691834 2 Q9H871 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.5714285714285823 0.4213572287400261 0.6734942465457265 1.0 0.756365081691834 2 Q9H871 1 +GTP binding protein, second domain [IPR031662] 0.5676307332749164 0.4096948780412297 0.6820297878206576 1.0 0.7631978695980361 2 P55039 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.5599064874342381 0.399465624132009 0.6895501481803037 1.0 0.7696233870804827 3 Q07864,P28340 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.5599064874342381 0.399465624132009 0.6895501481803037 1.0 0.7696233870804827 3 Q07864,P28340 2 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.5623721881390709 0.3938065317167654 0.6937238816946745 1.0 0.7716611022264699 2 Q9BSJ2 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.5623721881390709 0.3938065317167654 0.6937238816946745 1.0 0.7716611022264699 2 Q9BSJ2 1 +I-kappa-kinase-beta NEMO binding domain [IPR022007] 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.7821467159998711 2 O15111 1 +IKBKB, scaffold dimerization domain [IPR041185] 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.7821467159998711 2 O15111 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.5565293602103538 0.3765157281440981 0.7065335249295988 1.0 0.7843529860747764 2 Q9UEY8 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.4473394416324306 0.37062197533553 0.7109191120178107 1.0 0.7889090502470913 4 Q15019 1 +Glutaredoxin [IPR002109] 0.446150612163625 0.3669065846472381 0.7136886996531981 1.0 0.7916689376200559 4 O76003,P35754 2 +STAT transcription factor, protein interaction [IPR013799] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.7922861408406358 2 P42224 1 +STAT transcription factor, DNA-binding [IPR013801] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.7922861408406358 2 P42224 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.7922861408406358 2 P42224 1 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.5498101080923263 0.3571179366290431 0.7210035171757654 1.0 0.7953747461127931 2 Q92538 1 +Myotubularin-like phosphatase domain [IPR010569] 0.5443050780863942 0.3557515715615402 0.7220266196894796 1.0 0.7961899206493199 3 Q13614 1 +Phospholipase/carboxylesterase/thioesterase [IPR003140] 0.5411771025144663 0.3472845021916075 0.7283775925770215 1.0 0.8019308504521863 3 Q5VWZ2 1 +Phosphofructokinase domain [IPR000023] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.8020650883869433 3 P08237 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.3610996188284479 0.3445473057907181 0.7304347263702007 1.0 0.8020650883869433 7 Q13614,Q06124 2 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.5332632483321552 0.3263251082580743 0.7441783934205719 1.0 0.8149711444358971 3 Q96G03 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.5292226767971868 0.315885255950534 0.7520896034198641 1.0 0.8215809235019333 3 O15344,Q9H871 2 +FFD box [IPR025761] 0.5322816243061782 0.3090815414682875 0.7572594999774638 1.0 0.8262621179660644 2 Q8ND56 1 +TFG box [IPR025768] 0.5322816243061782 0.3090815414682875 0.7572594999774638 1.0 0.8262621179660644 2 Q8ND56 1 +UAS [IPR006577] 0.5252920943001476 0.3059029077282055 0.7596785719762877 1.0 0.8279344063312167 3 O94888 1 +Vps16, C-terminal [IPR006925] 0.5305287759275632 0.304489511441737 0.7607549822997932 1.0 0.828785171230179 2 Q9H269 1 +Transcription factor IIS, N-terminal [IPR017923] 0.4096051690005554 0.2615806377050907 0.7936447732538683 1.0 0.8602679515115431 4 Q14241 1 +Aminoacyl-tRNA synthetase, class II [IPR006195] 0.2872185947442221 0.2597550320327996 0.7950527397541782 1.0 0.8610481295320443 12 P49591,O43776,Q9Y285,A2RTX5 4 +Disks large homologue 1, N-terminal PEST domain [IPR019590] 0.5118317265556684 0.2580126779755945 0.796397122804889 1.0 0.8612523111151288 2 Q92796 1 +PDZ-associated domain of NMDA receptors [IPR019583] 0.5118317265556684 0.2580126779755945 0.796397122804889 1.0 0.8612523111151288 2 Q92796 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.8616450133878715 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.8616450133878715 2 P22314 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.8616450133878715 2 P22314 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.8616450133878715 2 P22314 1 +RBM1CTR [IPR012604] 0.4966403739410042 0.2237375077637853 0.8229615587092638 1.0 0.8841787912206124 2 Q96E39 1 +WHEP-TRS domain [IPR000738] 0.3928675825781967 0.2196202725853359 0.8261669016148494 1.0 0.8869423978255969 4 P07814,P41250,P23381 3 +Dynamin, GTPase domain [IPR001401] 0.4863695141423243 0.216799842037682 0.8283643350674756 1.0 0.8879406529682734 3 P50570 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.4817207648080846 0.2073947683878155 0.8357015680062179 1.0 0.8947786754120834 3 Q14241 1 +EF-hand, Ca insensitive [IPR014837] 0.4786674459380275 0.2013657791652081 0.8404125713987589 1.0 0.8969693514567638 3 Q13813,P12814 2 +D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.3849751534638996 0.2013123589545192 0.8404543393399684 1.0 0.8969693514567638 4 O43175,Q13363,Q9UBQ7 3 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.3849751534638996 0.2013123589545192 0.8404543393399684 1.0 0.8969693514567638 4 O43175,Q13363,Q9UBQ7 3 +Forkhead-associated (FHA) domain [IPR000253] 0.2650986721351289 0.1993716353112008 0.841972046812189 1.0 0.8973775865986129 13 P85037,Q5SW79 2 +SH2 domain [IPR000980] 0.2641552572737697 0.1962458140916285 0.8444177707038465 1.0 0.8993001115591707 13 P46108,P46109 2 +SH3 domain [IPR001452] 0.2080792596234669 0.1915508791396736 0.8480940226374478 1.0 0.9028093045882783 43 P46109,Q92783,Q9UNF0,Q9UQB8,P46108,A1X283,O60504 7 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.3691902952353088 0.167633790998539 0.8668713859810084 1.0 0.919571174437136 4 P41240,Q05397,P07948 3 +K Homology domain [IPR004087] 0.2290178618785152 0.1622809883644987 0.8710845853169027 1.0 0.9218631957097048 23 Q9Y6M1,Q96AE4 2 +Peptidase C2, calpain, domain III [IPR022683] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.9218631957097048 2 P17655 1 +Calpain subdomain III [IPR033883] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.9218631957097048 2 P17655 1 +Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.9218631957097048 2 P17655 1 +Peptidase C2, calpain, catalytic domain [IPR001300] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.9218631957097048 2 P17655 1 +Translation elongation factor EFTu/EF1A, C-terminal [IPR004160] 0.3623849477238256 0.1543410896305111 0.8773408006016752 1.0 0.9248716791895764 4 Q9Y450,Q05639 2 +Methyltransferase type 11 [IPR013216] 0.4589541338007704 0.1527486099811372 0.8785965253103973 1.0 0.9253799563975224 2 Q6FI81 1 +Myosin tail [IPR002928] 0.4511981297486678 0.1524731990497646 0.8788137273282681 1.0 0.9253799563975224 3 Q7Z406,P35579 2 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.3158818367943752 0.1493747951079379 0.8812578991722839 1.0 0.9269086462014788 6 Q9P2J5,P26640,P41252,Q15031,Q9NSE4 5 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.3158818367943752 0.1493747951079379 0.8812578991722839 1.0 0.9269086462014788 6 Q9P2J5,P26640,P41252,Q15031,Q9NSE4 5 +Cullin, N-terminal [IPR001373] 0.2784259949568319 0.1464905155323487 0.8835341766603102 1.0 0.928605687547708 8 Q86Y37 1 +Replication factor C, C-terminal [IPR013748] 0.4471069549970584 0.1460179262673377 0.883907236986669 1.0 0.928649448082732 3 P40937,P35250 2 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.4542798714577963 0.1453482540308914 0.8844359179949435 1.0 0.9287835183079914 2 Q9NR33 1 +MIF4G-like, type 3 [IPR003890] 0.2693588454927088 0.1239444795582722 0.9013592348538744 1.0 0.942172449124066 8 Q04637,Q9HCG8,Q9HAU5,P78344 4 +GTP binding domain [IPR006073] 0.2308017133871113 0.1216610631206869 0.9031674512302788 1.0 0.942172449124066 15 Q9NTK5,Q969Y2 2 +K Homology domain, type 1 [IPR004088] 0.2137688555078277 0.1174408428225793 0.9065107200961148 1.0 0.9449564872430484 24 Q9Y6M1,Q96AE4 2 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.4312007011393557 0.1132402167813441 0.9098401123288014 1.0 0.9473697490692312 2 O94973 1 +PWI domain [IPR002483] 0.3177005045610351 0.1075250628679206 0.9143724432883472 1.0 0.951028799589439 5 Q8IYB3,Q5T8P6 2 +Peptidase M24 [IPR000994] 0.293569255741514 0.1047241599291455 0.9165946905211536 1.0 0.9526329090653828 6 Q9Y5B9,Q9UQ80 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9565748993170564 3 P52701,P43246 2 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9565748993170564 3 P52701,P43246 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9565748993170564 3 P52701,P43246 2 +DNA mismatch repair protein MutS, core [IPR007696] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9565748993170564 3 P52701,P43246 2 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.1873342387995009 0.0919882214645603 0.9267073978216244 1.0 0.960293686648 69 Q9H4L7,Q14527,Q12873,Q9UPY3,P38935,O14646,Q9Y620 7 +Nuclear transport factor 2, eukaryote [IPR018222] 0.3997029568510926 0.0864014814619146 0.9311472693000178 1.0 0.963825138004673 3 Q13283 1 +Nuclear transport factor 2 domain [IPR002075] 0.3997029568510926 0.0864014814619146 0.9311472693000178 1.0 0.963825138004673 3 Q13283 1 +AMPK, C-terminal adenylate sensor domain [IPR032270] 0.4052001168565673 0.0854361025817486 0.9319146923667224 1.0 0.9642073444899314 2 Q13131 1 +LsmAD domain [IPR009604] 0.4022787028922013 0.0828264961104718 0.9339895006597768 1.0 0.9653406790293968 2 Q8WWM7 1 +Ataxin 2, SM domain [IPR025852] 0.4022787028922013 0.0828264961104718 0.9339895006597768 1.0 0.9653406790293968 2 Q8WWM7 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.3092662964045556 0.0758161099843126 0.9395653991006364 1.0 0.9703878541393232 4 Q08J23,Q96P11,P46087 3 +Anticodon-binding [IPR004154] 0.2946246864955015 0.0750949280200719 0.9401391832855592 1.0 0.9706226940184736 5 P26639,A2RTX5 2 +MHC class I-like antigen recognition-like [IPR011161] 0.3857824556512375 0.0738826724561498 0.941103743538946 1.0 0.9708892269971618 3 Q9UNN8 1 +Molybdenum cofactor sulfurase, C-terminal [IPR005302] 0.3850281654913468 0.0732635022964139 0.9415964345678468 1.0 0.9708892269971618 3 Q969Z3 1 +MOSC, N-terminal beta barrel [IPR005303] 0.3850281654913468 0.0732635022964139 0.9415964345678468 1.0 0.9708892269971618 3 Q969Z3 1 +GHMP kinase N-terminal domain [IPR006204] 0.3825248392752745 0.0712508017590643 0.9431981501644426 1.0 0.9714231798977624 3 Q03426,P51570 2 +Translational (tr)-type GTP-binding domain [IPR000795] 0.2159807994458389 0.0703852067004732 0.9438870653880996 1.0 0.9714231798977624 12 O60841,P13639,P46199,Q9Y450,Q05639 5 +Histone deacetylase domain [IPR023801] 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9714231798977624 3 O15379,Q92769 2 +Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.2666018507977088 0.0637450906618992 0.9491732005752992 1.0 0.9723021503099522 6 Q9BTE6,A2RTX5 2 +Cullin homology domain [IPR016158] 0.2527794031597389 0.063460316541133 0.94939995833263 1.0 0.9723021503099522 7 Q93034,Q9UJX6,Q13620,Q13618,Q13616,Q13617 6 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.2945030521279647 0.0614658623803785 0.9509882008545234 1.0 0.9728619710822834 4 P61221,Q16134 2 +Sec63 domain [IPR004179] 0.3631474820494252 0.0577605331161695 0.9539393756761294 1.0 0.9731567574750348 3 Q8N3C0 1 +Formin, GTPase-binding domain [IPR010473] 0.2901077322184618 0.0577549509746695 0.9539438221578244 1.0 0.9731567574750348 4 Q27J81,O60879 2 +Formin, FH3 domain [IPR010472] 0.2901077322184618 0.0577549509746695 0.9539438221578244 1.0 0.9731567574750348 4 Q27J81,O60879 2 +Threonine-tRNA ligase catalytic core domain [IPR033728] 0.3613222484396949 0.0566701070936354 0.954807986817447 1.0 0.9732164347262592 3 A2RTX5 1 +Uncharacterised domain CHP00451 [IPR004521] 0.3546596552731517 0.0526966603562849 0.9579735999800456 1.0 0.9750243469466356 2 Q9ULC4 1 +FERM adjacent (FA) [IPR014847] 0.256313710061311 0.0516579463015803 0.9588012464613156 1.0 0.9751582913192764 6 Q9Y4F1 1 +Cullin protein, neddylation domain [IPR019559] 0.2527054694354957 0.0478526167609985 0.9618337024432286 1.0 0.977532837956448 6 Q93034,Q13620,Q13616,Q13618,Q13617 5 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 0.9779660087090416 2 P04439 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 0.9779660087090416 2 P04439 1 +Immunoglobulin C1-set [IPR003597] 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 0.9779660087090416 2 P04439 1 +Dbl homology (DH) domain [IPR000219] 0.2207259953161584 0.0442309179913357 0.964720337169272 1.0 0.9786916671789646 9 Q92974,Q92888,P11274,Q9Y4F1,Q12802,Q9H8V3,Q14155,Q9NZM3 8 +Ribosomal protein L18e/L15P [IPR021131] 0.323202805376975 0.039888128057843 0.9681823160089824 1.0 0.9811381010695004 3 Q07020,P46776 2 +AAA ATPase, AAA+ lid domain [IPR041569] 0.1844863054541635 0.0339437757151481 0.9729219853121028 1.0 0.984516938549842 17 P62195,Q9UN37,P62333,O75351,P17980 5 +Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.2746931618936332 0.0304787915187595 0.9756852074385648 1.0 0.9866004876372642 3 P49588,Q9BTE6 2 +SAB domain [IPR007477] 0.2390414962010572 0.0281293849318745 0.9775589575554609 1.0 0.9877822571476385 3 P11171,Q9Y2J2 2 +Band 4.1, C-terminal [IPR008379] 0.2390414962010572 0.0281293849318745 0.9775589575554609 1.0 0.9877822571476385 3 P11171,Q9Y2J2 2 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.2304045237316181 0.0258372961419127 0.9793871137508856 1.0 0.9892727803640884 5 O43776 1 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.2089245962485502 0.0190845124957309 0.9847736864192966 1.0 0.9929240263932598 7 P49591,A2RTX5 2 +Pleckstrin homology domain [IPR001849] 0.1533923303834899 0.0083442719276536 0.9933423115168802 1.0 0.9997647833585842 35 Q96P47,Q9Y5S2,Q13464,Q9NQW6,Q12756,Q9BXB4,Q9BZF1,O95248,P19174,O60333,Q96JJ3,P50570,O15020,Q8N556,Q92888,Q96AC1,Q9Y4F1,Q9H4L5,Q92974,Q14155,Q6IQ23,Q12802,Q9Y243,Q96SU4,P31751,O75116,P11274,O14654,P22059,Q8IYI6,O94887,Q01082,Q96TA1,Q9NZM3 34 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a05e9cef8545cdf637d1f41a6255f836f0fa0996 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain [IPR002073]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BTB/POZ domain-containing protein KCTD11/21, C-terminal domain [IPR045763]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHAT domain [IPR024983]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper homeostasis CutC domain [IPR023648]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Costars domain [IPR027817]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dihydroorotate dehydrogenase domain [IPR005720]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disintegrin domain [IPR001762]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E2F transcription factor, CC-MB domain [IPR032198]", "E2F/DP family, winged-helix DNA-binding domain [IPR003316]", "E3 Ubiquitin ligase MUL1-like [IPR022170]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor-binding domain [IPR001799]", "Ephrin-B ectodomain [IPR034255]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM69, protein-kinase domain [IPR022049]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FOX1, RNA recognition motif [IPR034237]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fox-1 C-terminal domain [IPR025670]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucose-methanol-choline oxidoreductase, C-terminal [IPR007867]", "Glucose-methanol-choline oxidoreductase, N-terminal [IPR000172]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Inhibitor of growth protein, N-terminal histone-binding [IPR024610]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Interleukin-1 receptor-associated kinase 1, death domain [IPR035533]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Mitogen-activated protein kinase kinase kinase, N-terminal [IPR045801]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-acetyltransferase ESCO, acetyl-transferase domain [IPR028009]", "N-acetyltransferase ESCO, zinc-finger [IPR028005]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAS domain [IPR000014]", "PAS fold [IPR013767]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Paired DNA-binding domain [IPR043182]", "Paired domain [IPR001523]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein FAM210A/B-like domain [IPR009688]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein NPAT, C-terminal domain [IPR031442]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B gamma, catalytic domain [IPR034675]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAP80, N-terminal [IPR040714]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raf-like Ras-binding [IPR003116]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SBF1/SBF2 domain [IPR022096]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Sialate O-acetylesterase domain [IPR005181]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm4 [IPR034101]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "SoHo domain [IPR003127]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIID subunit TAF5, NTD2 domain [IPR007582]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUP1-like enhancer of split [IPR011494]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Tectonic domain [IPR011677]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone C, N-terminal [IPR031925]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UME domain [IPR012993]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 38 [IPR033840]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Villin headpiece [IPR003128]", "Vinculin-binding site-containing domain [IPR015009]", "Vinexin, SH3 domain 1 [IPR035609]", "Vinexin, SH3 domain 2 [IPR035608]", "Vinexin, SH3 domain 3 [IPR035607]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZN598/Hel2, RING finger [IPR041888]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APMAP", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCKDHA", "BCKDK", "BCL10", "BCOR", "BCR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C1orf35", "C2CD5", "C3orf58", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COMMD2", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTC", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCP2", "DCTN1", "DCUN1D1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "E2F3", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ERP44", "ESCO2", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM192A", "FAM208A", "FAM210B", "FAM49B", "FAM8A1", "FAM91A1", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXC1", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT3", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBTD1", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED25", "MEPCE", "METAP2", "METTL13", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGA", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDZ", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA40", "NAA50", "NACC1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND5", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFRKB", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRP12", "RSF1", "RSPRY1", "RTCA", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIAE", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A4", "SLC38A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6", "TAGLN2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCC", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLK2", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC28", "TTC4", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UHRF1BP1", "UIMC1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WDHD1", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WDR47", "WDR62", "WFS1", "WIZ", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["AARS", "AARSD1", "ABCE1", "ABCF2", "ACTN1", "ADD3", "AFAP1", "AGAP3", "AIMP2", "AKAP13", "AKR1A1", "AKR1B1", "AKT2", "AKT3", "ANAPC2", "ANK3", "ANLN", "ANP32A", "AP1M1", "AP2A2", "AP3B1", "AP3D1", "AP3S1", "APEX1", "ARAF", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARIH2", "ASCC3", "ASH2L", "ATR", "ATXN2L", "AURKA", "BAG3", "BAIAP2", "BCR", "BSDC1", "BTAF1", "BZW1", "BZW2", "CACUL1", "CACYBP", "CAMK1", "CAND1", "CAP1", "CAPN2", "CARS", "CBX1", "CBX8", "CDC34", "CDC42BPB", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CEP170", "CFL1", "CFL2", "CHAC2", "CHD1", "CHD3", "CHUK", "CIAPIN1", "CLASP1", "CLASP2", "CLIC1", "CNN2", "CNN3", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS5", "COPS6", "COPS7A", "COPZ1", "COTL1", "CPNE8", "CPPED1", "CRK", "CRKL", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CTBP1", "CTPS1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "DCTN1", "DENR", "DIAPH2", "DICER1", "DIS3", "DLG3", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM2", "DPP9", "DPYSL2", "DPYSL3", "DRG2", "DSTN", "DUSP12", "DUSP3", "ECT2", "EEA1", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EHD1", "EHD4", "EIF2AK2", "EIF2B5", "EIF3A", "EIF3E", "EIF3K", "EIF3L", "EIF4A1", "EIF4G1", "EIF4G2", "EIF5", "EIF5B", "ELMO2", "ELOA", "ELOB", "ELP3", "EPB41", "EPB41L3", "EPRS", "EPS15", "EPS15L1", "ERAP2", "ETF1", "ETFDH", "EXOC8", "EZR", "FAF1", "FAM129B", "FARP1", "FARP2", "FARSA", "FERMT2", "FHL1", "FKBP10", "FKBP15", "FKBP3", "FOXK1", "FUBP1", "FUCA1", "G3BP1", "GALK1", "GARS", "GBF1", "GCLM", "GFPT1", "GGA1", "GINS4", "GLO1", "GLRX", "GLRX3", "GMFB", "GMPPA", "GMPS", "GPHN", "GRHPR", "GSK3B", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTPBP3", "HACE1", "HBS1L", "HDAC2", "HDAC3", "HDGF", "HECTD1", "HGS", "HLA-A", "HLTF", "HMGB1", "HMGB3", "HOOK3", "HUWE1", "IARS", "IARS2", "IDH2", "IGF2BP2", "IGHMBP2", "ILKAP", "INA", "INF2", "IPO7", "IPO8", "IRAK1", "IRS4", "ITCH", "ITSN2", "KCTD21", "KIF13B", "KIF1A", "KIF1B", "KPNA1", "KPNA6", "L2HGDH", "LARP1", "LARP4B", "LARP7", "LARS", "LARS2", "LIMA1", "LSM14A", "LTA4H", "LYN", "LYPLAL1", "MAN2A1", "MAP2K1", "MAP2K2", "MAPK14", "MAPRE2", "MARC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCTS1", "MID1", "MOCOS", "MOV10", "MSH2", "MSH6", "MSN", "MTAP", "MTIF2", "MTMR2", "MTOR", "MVK", "MYH14", "MYH9", "NAA40", "NARS", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NFATC2IP", "NLN", "NME1", "NOP2", "NRBP1", "NSD2", "NSUN2", "NSUN5", "NUDC", "NUDCD1", "NUDCD3", "OCRL", "OLA1", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUD4", "OXSR1", "PA2G4", "PABPC1", "PABPC4", "PACSIN2", "PAK2", "PBK", "PCYOX1", "PDCD4", "PDE6D", "PDLIM1", "PDLIM5", "PFKM", "PGLS", "PGM2", "PHGDH", "PI4KA", "PIK3R4", "PIN1", "PKMYT1", "PKN1", "PLCG1", "PLD6", "PLEKHA7", "POLD1", "POLE", "POLE4", "PPAT", "PPM1G", "PPP1R7", "PPP4R1", "PREPL", "PRKAA1", "PRKACA", "PROCR", "PRPF40A", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSMA1", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMC1", "PSMC3", "PSMC5", "PSMC6", "PSMD12", "PSMD13", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME2", "PSME3", "PTK2", "PTPN11", "RABGAP1", "RAD23A", "RAD23B", "RAD54B", "RBM26", "RBM3", "RBMXL1", "RFC2", "RFC5", "RIPK1", "RMND5A", "RNGTT", "ROCK1", "ROCK2", "RPL18", "RPL27A", "RPS2", "RPS4X", "RUFY1", "SAE1", "SARM1", "SARS", "SBF1", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC31A", "SEPHS1", "SEPT2", "SH3PXD2B", "SIPA1", "SMARCAD1", "SMG1", "SMNDC1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SORBS3", "SPART", "SPTAN1", "SPTBN1", "SPTBN2", "SRPK1", "SRRM1", "SSB", "SSRP1", "STAM", "STAT1", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "SUPT16H", "TARS", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCC", "TBCE", "TES", "TFAM", "TFCP2", "TNPO1", "TNPO3", "TPP1", "TRIM21", "TRIM28", "TRMT11", "TTK", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "TUBGCP2", "TWF2", "UBA1", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2L3", "UBE2O", "UBE2S", "UBE3C", "UBR4", "UBR7", "UBXN1", "UBXN7", "UHRF1BP1", "UMPS", "UPF2", "USP13", "USP19", "USP24", "USP9X", "UXS1", "VARS1", "VPS13A", "VPS16", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WNK1", "XIAP", "XPO5", "XPO7", "XPOT", "YBX1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZCCHC11", "ZYX"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0ca6ee10c7b1a692d2901563d809f5435454533b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Proteasome alpha-type subunit [IPR023332]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..700e1c213cfb83371d36cea12335e350549ef2cb --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6cf26dbd4e0df3bd8bc888ea0ec4d9abbd7bcb10a9d7cb84fa9fef1f884cf8bb +size 189144 diff --git 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b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a405bd55c9eae4c18130b8bd9d9b7d170ea155b543113004bc5c8b180b654b65 +size 497757 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b48bc7eb8d643d85ae8ed531a50d3c66e8d1c76b --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome, subunit alpha/beta [IPR001353] 12 14 3.510913350350584 0.0004465699351419 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 1.0 5.253086721125362e-05 0.000440337804097 4.264788425202475e-13 3.5944371165659605e-15 +Proteasome B-type subunit [IPR023333] 6 7 3.0153029456467166 0.0025672269554928 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 8.064461453409737e-06 6.936272072908627e-05 1.5998774522859254e-10 2.0456909676363405e-08 +Proteasome alpha-type subunit [IPR023332] 5 7 2.66950152293713 0.0075963928629572 3.3640776699029127 7.0 -0.0819805286147498 0.4543740069752794 1.9566840569754116 0.0 1.1177702159542848 0.3184279071165019 1.0 1.0 1.0 0.0004628530549595 8.641434277596474e-08 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..378f7fc6130a7bc7faea9830d70aed78c4f556f6 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2586, + "title": "Average number of proteins per term", + "value": 1.2935034802784222 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0951d71997ee98005d0a330874171327b06f1313 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f10925a28d86ed56d1838ce56146e4d1e937bf81 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,145 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome, subunit alpha/beta [IPR001353] 0.8684718995584977 3.5109133503505836 0.0004465699351419 0.6849701192766078 0.0404090670952242 14 P25788,P25789,P20618,Q99436,P49721,P28072,P28070,P60900,P28074,P28066,P49720,P25786 12 +Proteasome B-type subunit [IPR023333] 0.9438267992978314 3.0153029456467166 0.0025672269554928 0.9987025899043442 0.0404090670952242 7 P20618,P49721,P28072,P28070,P28074,P49720 6 +Proteasome alpha-type subunit [IPR023332] 0.8626434325729313 2.66950152293713 0.0075963928629572 0.9999999972708205 0.0450831436830327 7 P25788,P25789,P60900,P25786,P28066 5 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9985392930178209 2.1203319487810792 0.0339780611679716 1.0 0.1003050983794231 2 P48735 1 +Glutathione S-transferase, Mu class [IPR003081] 0.9678644463920536 1.9949827737115315 0.0460447586956198 1.0 0.1207624198649827 2 P28161 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.8323760532242036 1.921191016081965 0.0547076303619373 1.0 0.1353550854081535 4 Q01105,Q99733 2 +Prefoldin beta-like [IPR002777] 0.9436002337814142 1.8138203744375008 0.0697053846787898 1.0 0.1592720051979852 3 Q9UHV9,Q9NQP4 2 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.9427235534774993 1.8104498240211064 0.0702260587473495 1.0 0.1597225927182462 3 P28074,P28072 2 +Snf7 family [IPR005024] 0.767106740274994 1.803657189655068 0.0712850646686438 1.0 0.1613624969314875 5 Q9HD42 1 +14-3-3 protein [IPR000308] 0.7130739982451005 1.7945239204549257 0.072729584127241 1.0 0.1634759334839749 6 Q04917,P61981,P27348,P63104,P31946 5 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.9190768331872676 1.7935328581781111 0.0728877615263043 1.0 0.1634759334839749 2 Q96PU5 1 +Peptidase C69, dipeptidase A [IPR005322] 0.9094361671048844 1.7534678582035377 0.079521731993704 1.0 0.1732461659104622 2 Q0VDG4 1 +Transport protein particle (TRAPP) component [IPR007194] 0.9024247735904192 1.724284954204665 0.0846564140970651 1.0 0.1807774457927419 2 O43617 1 +Protein transport protein Sec23 [IPR037364] 0.8916155419222944 1.6792279806384909 0.0931076207546035 1.0 0.1926923166843112 2 Q15437 1 +Initiation factor 2B-related [IPR000649] 0.7673964887688096 1.6513192001468655 0.0986734137768423 1.0 0.2006049119708446 4 P49770,Q9BV20 2 +Calponin/LIMCH1 [IPR001997] 0.8819748758399136 1.638981732004823 0.1012170643045966 1.0 0.2032596821023657 2 Q99439 1 +Profilin1/2/3, vertebrate [IPR005454] 0.8816827344434759 1.6377613549839911 0.1014714860278738 1.0 0.2032596821023657 2 P07737 1 +Profilin [IPR005455] 0.8816827344434759 1.6377613549839911 0.1014714860278738 1.0 0.2032596821023657 2 P07737 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.7617655656240923 1.6276957311914342 0.1035894187151611 1.0 0.2057467256508499 4 P11908,Q14558,P60891 3 +Dynein family light intermediate chain [IPR022780] 0.8720420683610918 1.5974658445552925 0.1101619053355822 1.0 0.2135522392787223 2 O43237 1 +Dynein 1 light intermediate chain [IPR008467] 0.8720420683610918 1.5974658445552925 0.1101619053355822 1.0 0.2135522392787223 2 O43237 1 +Beta tubulin [IPR002453] 0.6693695146902517 1.5952209706813745 0.1106628308682551 1.0 0.2138819735615155 6 P07437,Q9BUF5,Q9BVA1 3 +UBAP2/protein lingerer [IPR022166] 0.8661992404323766 1.5730250450084138 0.1157130191344975 1.0 0.2208442520666158 2 Q5T6F2 1 +Tubulin [IPR000217] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.2257736769206914 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Sorting nexin-5/6/32 [IPR014637] 0.8615249780893985 1.5534637567143352 0.1203123814303359 1.0 0.2259461280892148 2 Q9UNH7 1 +Translin family [IPR002848] 0.8609406952965295 1.5510181209066844 0.1208973414162133 1.0 0.2265511050016867 2 Q15631 1 +Protein arginine N-methyltransferase [IPR025799] 0.6992455325530592 1.5101212797559305 0.1310124805531733 1.0 0.2402824643336924 5 Q6P2P2,Q86X55 2 +Microtubule-associated protein RP/EB [IPR027328] 0.8498393222319669 1.5045352885462846 0.1324435942025292 1.0 0.2420488583800287 2 Q15555 1 +Vacuolar protein sorting-associated protein 4 [IPR031255] 0.847794332456915 1.495970174086595 0.1346614277435422 1.0 0.2449607768120222 2 Q9UN37 1 +Lupus La protein [IPR002344] 0.8422436459246347 1.472719834291217 0.1408265961329684 1.0 0.2525809428959263 2 P05455 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.8361086765994747 1.4470206725907573 0.1478911337682826 1.0 0.2594616498811255 2 O60884 1 +Tropomyosin [IPR000533] 0.8346479696172999 1.440901953306437 0.1496123841806604 1.0 0.2613643632470539 2 P67936 1 +Macrophage migration inhibitory factor [IPR001398] 0.8340636868244257 1.4384545034654566 0.1503051375826967 1.0 0.2620964840113645 2 P30046 1 +Smooth muscle protein/calponin [IPR003096] 0.8399406770703057 1.4116886055693074 0.1580416698465296 1.0 0.2696860972424991 3 Q99439 1 +UV excision repair protein Rad23 [IPR004806] 0.8191644756061984 1.376061922443628 0.1688024629957465 1.0 0.2800020329101992 2 P54725 1 +Prefoldin alpha-like [IPR004127] 0.8185801928133252 1.373616225183566 0.1695608570939173 1.0 0.2803608545043927 2 Q99471 1 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.8179959100204623 1.3711706390807643 0.1703217686186604 1.0 0.2812593190599335 2 Q4J6C6 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.546551328193488 1.363931884570491 0.1725890046517295 1.0 0.2836398511520222 8 P17987,P50991,P78371,P40227,P48643,P49368 6 +CTP synthase [IPR004468] 0.8141980718667869 1.3552772770226205 0.175329231836415 1.0 0.2864190736127411 2 P17812 1 +26S proteasome regulatory subunit P45-like [IPR005937] 0.6148864520000414 1.3434194243126514 0.1791362006827079 1.0 0.2911666970241878 6 P62195,P62191,P17980,P62333 4 +Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515] 0.8042652643879697 1.313739977431123 0.188933722703636 1.0 0.3023407220987641 2 P11908 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.8116775882682399 1.3014967698924529 0.1930884694374071 1.0 0.3061476284274277 3 P39687 1 +Chaperone DnaJ [IPR012724] 0.8109457151107637 1.2986455781918953 0.1940655886647841 1.0 0.3066343907652386 3 O60884 1 +La domain containing protein [IPR045180] 0.6499999999999894 1.294505377518815 0.1954909130226128 1.0 0.3080058511585309 5 Q6PKG0,Q4G0J3,Q92615,P05455 4 +Ras GTPase-activating protein-binding protein [IPR039539] 0.7975460122699384 1.2856728855636208 0.1985572479464972 1.0 0.3106285802720155 2 Q13283 1 +Translation initiation factor IF- 2 [IPR015760] 0.7952088810984553 1.2759177142750913 0.2019846084059482 1.0 0.3140903171002899 2 O60841 1 +Alpha-D-phosphohexomutase superfamily [IPR005841] 0.7922874671340915 1.2637296690641644 0.20632707230068 1.0 0.3193068874743019 2 Q96G03 1 +Ribosomal protein S5 [IPR000851] 0.7890739117732978 1.2503309987817213 0.2111786590968121 1.0 0.323523704042865 2 P15880 1 +Prenylcysteine oxidase [IPR017046] 0.7864446392053814 1.2393753047523763 0.2152065425299598 1.0 0.3275095432730584 2 Q9UHG3 1 +Peptidase M3A/M3B [IPR045090] 0.7943083237754776 1.2338942449288812 0.2172423143248831 1.0 0.3294490957885642 3 Q9BYT8 1 +SNX17/27/31 [IPR037831] 0.7849839322231985 1.2332916326302763 0.2174669785425673 1.0 0.3294490957885642 2 Q15036 1 +Exportin 4/7-like [IPR044189] 0.7823546596552875 1.2223463754305572 0.2215766687790776 1.0 0.3335257656942345 2 Q9C0E2 1 +Translation initiation factor IF2/IF5 [IPR045196] 0.7730061349693375 1.1834914083832058 0.236614449545458 1.0 0.3504495799109706 2 P55010 1 +Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909] 0.7662868828512982 1.1556317458136716 0.2478318171770002 1.0 0.361882032309273 2 P49589 1 +Cysteine-tRNA ligase [IPR015803] 0.7662868828512982 1.1556317458136716 0.2478318171770002 1.0 0.361882032309273 2 P49589 1 +Microtubule associated protein 1 [IPR026074] 0.7621148331742907 1.1091759554502054 0.2673542831431179 1.0 0.3800869577834541 3 P78559 1 +NudC family [IPR037898] 0.7521917007598061 1.070967662250609 0.2841839701861794 1.0 0.3959589153563901 3 Q8IVD9,Q9Y266 2 +Coatomer gamma subunit [IPR017106] 0.7449605609114869 1.0676769366407295 0.2856662654088406 1.0 0.3967416553959516 2 Q9Y678 1 +Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852] 0.7382413087934604 1.040143632087027 0.2982731750387626 1.0 0.4077798029227562 2 Q86VP6 1 +Exportin-1/5 [IPR045065] 0.7370727432077266 1.0353653045999394 0.3004983424180585 1.0 0.409856916399314 2 Q9HAV4 1 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.742641943121501 1.0343371102527938 0.3009785937723004 1.0 0.4102955421693035 3 Q96P16 1 +Glycosyl transferase, family 8 [IPR002495] 0.7274320771253457 0.9960677479400408 0.3192172291111852 1.0 0.4262752588656117 2 P46976 1 +Small GTPase superfamily, ARF type [IPR024156] 0.6121017246419233 0.9956584499310884 0.3194161247999738 1.0 0.4262752588656117 4 P84085,P62330,P18085 3 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.5372152898869127 0.9835276621430789 0.3253478077673417 1.0 0.4307984797165108 6 P09960,Q6P179 2 +Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015] 0.720712825007302 0.9688197135901012 0.332635148918571 1.0 0.437980903820481 2 P09960 1 +Ezrin/radixin/moesin [IPR011174] 0.7142022209234368 0.9262861120278209 0.3542973113615595 1.0 0.4559350343857978 3 P15311,P26038 2 +Phosphatidylinositol kinase [IPR015433] 0.7136905815697505 0.9243591255695984 0.3552993684872438 1.0 0.4564352543010495 3 P42356 1 +Molecular chaperone regulator BAG [IPR039773] 0.7116418574323677 0.916649811906388 0.3593261732368371 1.0 0.459099547426117 3 O95817 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.4448195878349876 0.9100913383621598 0.3627743421177114 1.0 0.4619076556949295 9 P18085,Q9NR31,P36405,Q9Y6B6,P40616,P62330,P84085 7 +Small GTPase, Ras-type [IPR020849] 0.7028921998247153 0.8972033401897793 0.369610423191967 1.0 0.4680421813932564 2 P11233 1 +UDPGP family [IPR002618] 0.7014314928425343 0.8913796179614278 0.3727255484262577 1.0 0.4708687192136309 2 Q16222 1 +Ribosomal protein L12/P1/P2 family [IPR027534] 0.6985100788781848 0.8797551678241021 0.3789919562722827 1.0 0.4764663400535701 2 P05387 1 +Phosphatidylinositol transfer protein [IPR001666] 0.6926672509494768 0.8566018443905928 0.3916649660584888 1.0 0.4885892919571886 2 Q00169 1 +Nucleoside diphosphate kinase [IPR001564] 0.6925859678706816 0.8455107443146228 0.3978257363552182 1.0 0.4936551603716863 3 P15531 1 +Proteasome activator PA28 [IPR009077] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.5108295949293017 3 Q9UL46,P61289 2 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.679228746713423 0.8038738130779437 0.4214698551143501 1.0 0.5126875990578263 2 P06737 1 +Glycosyl transferase, family 35 [IPR000811] 0.679228746713423 0.8038738130779437 0.4214698551143501 1.0 0.5126875990578263 2 P06737 1 +Initiation factor 4G [IPR045208] 0.6805961426066642 0.8013465615852734 0.4229310424399597 1.0 0.5141982490595843 3 Q04637,P78344 2 +ADF/Cofilin [IPR017904] 0.677966101694906 0.7917282441078037 0.428519149903209 1.0 0.5184831036955448 3 P60981,Q9Y281 2 +Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101] 0.6757230499561953 0.7902489569121316 0.4293823899069002 1.0 0.5187876040352536 2 P49006 1 +Mini-chromosome maintenance protein [IPR031327] 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.526222767258173 6 P33992,P25205,P33991,P49736 4 +MT-A70-like [IPR007757] 0.6701723634239062 0.7687952296065907 0.4420148812582836 1.0 0.5284561682119814 2 Q9HCE5 1 +RNA-binding protein 26/27 [IPR045137] 0.6669588080631039 0.7564440568348901 0.4493830017155193 1.0 0.5338100332734649 2 Q5T8P6 1 +HAD-superfamily hydrolase, subfamily IIA [IPR006357] 0.6645236703682136 0.7429967495734124 0.4574836483403204 1.0 0.5397793341896728 3 Q9H0R4,A6NDG6 2 +Twinfilin [IPR028458] 0.6555652936021175 0.7130912402578841 0.4757892996532438 1.0 0.5529847770351858 2 Q6IBS0 1 +YTH domain containing protein [IPR045168] 0.6510812390414987 0.6950551133542154 0.4870207632530554 1.0 0.5620803472415979 3 Q9Y5A9,Q7Z739 2 +26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134] 0.64913818288052 0.6889574960761279 0.4908500155517481 1.0 0.564401129487248 2 O00232 1 +Importin subunit alpha [IPR024931] 0.5362987791345379 0.687763301837554 0.4916018495527687 1.0 0.5647044635306534 4 P52294,O60684 2 +L-lactate dehydrogenase [IPR011304] 0.6409582237803145 0.6586046987034349 0.5101496448293326 1.0 0.5769093291221092 2 P00338 1 +Glutathione Transferase family [IPR040079] 0.3880266862630505 0.654022663177642 0.5130972046918718 1.0 0.5794189394468037 10 P28161 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6371603856266477 0.6446580704759908 0.5191487939295145 1.0 0.5826904431865124 2 Q13310 1 +F-actin-capping protein subunit alpha [IPR002189] 0.6348232544551644 0.6361233663541203 0.5246960167513768 1.0 0.5859120975894734 2 P47755 1 +Protein phosphatase 2C family [IPR015655] 0.6285797779076577 0.6168624287671912 0.5373254702724712 1.0 0.594321499625582 3 O15355,Q9H0C8 2 +Rho-associated protein kinase 1/2 [IPR020684] 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.6062837383036723 2 O75116 1 +26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585] 0.617002629272577 0.5723266038939852 0.5671007295113126 1.0 0.6130946849984341 2 Q15008 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.615541922290396 0.5672036536520223 0.5705758260170795 1.0 0.6154679985408853 2 P84085 1 +Cullin [IPR045093] 0.4781428275970755 0.5669855506341906 0.5707239986469617 1.0 0.6154679985408853 5 Q93034,Q13620,Q13616 3 +ThiF/MoeB/HesA family [IPR045886] 0.377027978159468 0.5639354581547046 0.5727980575372651 1.0 0.6169328516415525 9 Q9GZZ9,Q9UBE0 2 +Hydantoinase/dihydropyrimidinase [IPR011778] 0.6104617182933951 0.5560845892079326 0.5781530296212103 1.0 0.620149387363568 3 Q16555,Q14195 2 +Monothiol glutaredoxin-related [IPR004480] 0.6082383873794988 0.5418473067932356 0.5879236990924857 1.0 0.627474488589834 2 O76003 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.5956763073327584 0.4992955086445578 0.6175712187461335 1.0 0.6518527231336739 2 P36405 1 +CPSF6/7 family [IPR034772] 0.5880806310254258 0.4742603537624184 0.6353142596231605 1.0 0.6689424574045166 2 Q8N684 1 +Ezrin/radixin/moesin-like [IPR000798] 0.3553730296045014 0.4624028847590392 0.6437924309900269 1.0 0.6765986399590818 9 P15311,P26038,Q9Y4F1,Q9Y2J2 4 +Glycoside hydrolase, family 29 [IPR000933] 0.5717207128250144 0.4222607334351904 0.6728347158481678 1.0 0.7041483509442986 2 P04066 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.5717207128250144 0.4222607334351904 0.6728347158481678 1.0 0.7041483509442986 2 P04066 1 +SH3-binding, glutamic acid-rich protein [IPR006993] 0.5679228746713523 0.4105864568839257 0.6813757960240987 1.0 0.7125102339338129 2 Q9UJC5 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.5676307332749164 0.4096948780412297 0.6820297878206576 1.0 0.7126177904259478 2 P55039 1 +DNA-directed DNA polymerase, family B [IPR006172] 0.5599064874342381 0.399465624132009 0.6895501481803037 1.0 0.7201844439395255 3 Q07864,P28340 2 +Gamma-tubulin complex component protein [IPR007259] 0.5623721881390709 0.3938065317167654 0.6937238816946745 1.0 0.7242510932831765 2 Q9BSJ2 1 +Septin [IPR016491] 0.4473394416324306 0.37062197533553 0.7109191120178107 1.0 0.7413051708379267 4 Q15019 1 +Transcription factor STAT [IPR001217] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.745351607856528 2 P42224 1 +Myotubularin family [IPR030564] 0.5443050780863942 0.3557515715615402 0.7220266196894796 1.0 0.7509982938813216 3 Q13614 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.5492258252994577 0.3554562979512985 0.7222477791503661 1.0 0.7509982938813216 2 O75150 1 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.7576998293610044 3 P08237 1 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.7576998293610044 3 P08237 1 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.7576998293610044 3 P08237 1 +Aldo-keto reductase [IPR020471] 0.5384165936313292 0.325461169286839 0.7448320666528603 1.0 0.7719982863183553 2 P15121 1 +FAM98 [IPR018797] 0.5331580484954859 0.3113922959954553 0.7555024098928045 1.0 0.7818044145589405 2 Q52LJ0 1 +Fructose-bisphosphate aldolase, class-I [IPR000741] 0.5243938066024102 0.2887301462622583 0.7727878913541775 1.0 0.7980948430678526 2 P04075 1 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.5131866890804759 0.2762610631106182 0.7823475597079625 1.0 0.8076450257104955 3 Q9NQ88 1 +Disks large 1-like [IPR016313] 0.5118317265556684 0.2580126779755945 0.796397122804889 1.0 0.8211654543753759 2 Q92796 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.8224802334709376 2 P22314 1 +Dynamin [IPR022812] 0.4863695141423243 0.216799842037682 0.8283643350674756 1.0 0.8520883733032983 3 P50570 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.485539000876442 0.2007302114019173 0.8409095352044278 1.0 0.8643052694907195 2 Q7L576 1 +Tight junction protein ZO [IPR005417] 0.467134092900983 0.1664417379002638 0.8678093299142811 1.0 0.8887742285775567 2 Q9UDY2 1 +Peptidase C2, calpain family [IPR022684] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.8921427968057711 2 P17655 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.4312007011393557 0.1132402167813441 0.9098401123288014 1.0 0.9274129012543478 2 O94973 1 +NSF attachment protein [IPR000744] 0.4291557113643075 0.1107419335430352 0.91182099231096 1.0 0.9290658337731056 2 Q99747 1 +Ribosomal protein S9 [IPR000754] 0.4279871457785641 0.1093389907274998 0.9129336218370956 1.0 0.9298331414221068 2 P62249 1 +Importin beta family [IPR040122] 0.3129676100729666 0.1001445495888849 0.9202295676206642 1.0 0.9365264312739228 5 Q92973 1 +DNA mismatch repair MutS family [IPR045076] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9384025273886668 3 P52701,P43246 2 +KH domain-containing BBP-like [IPR045071] 0.4070718877849112 0.0938991856122693 0.925189240767905 1.0 0.94046359144096 3 Q96PU8,Q15637 2 +Ataxin2-like [IPR045117] 0.4022787028922013 0.0828264961104718 0.9339895006597768 1.0 0.948290871105686 2 Q8WWM7 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.3092662964045556 0.0758161099843126 0.9395653991006364 1.0 0.9532036571495668 4 Q08J23,Q96P11,P46087 3 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.3060508623209523 0.0724347633084869 0.9422559203244494 1.0 0.9555583568466768 4 Q96BP3,Q13356,Q9H2H8 3 +Histone deacetylase family [IPR000286] 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9567003708790832 3 O15379,Q92769 2 +Histone deacetylase [IPR003084] 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9567003708790832 3 O15379,Q92769 2 +C-terminal binding protein [IPR043322] 0.3847502191060481 0.069160516349367 0.944861851208499 1.0 0.9567003708790832 2 Q13363 1 +Threonine-tRNA ligase, class IIa [IPR002320] 0.3613222484396949 0.0566701070936354 0.954807986817447 1.0 0.9645052554335618 3 A2RTX5 1 +Ribosomal protein L10P [IPR001790] 0.3571011104617182 0.0542595339664898 0.95672838924958 1.0 0.9658305313662572 3 P05388,Q7Z7H8 2 +Aminoacyl-tRNA synthetase, class Ic [IPR002305] 0.3318246415966805 0.0427834199543124 0.9658741808470256 1.0 0.973131900441902 3 P54577 1 +Ribosomal protein L15 [IPR030878] 0.3231083844580741 0.0427483105223609 0.9659021685154184 1.0 0.973131900441902 2 P46776 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.3313851548801866 0.0426244649600567 0.9660008929921552 1.0 0.973131900441902 3 Q9H857,Q5TFE4 2 +Translation Initiation factor eIF- 4e [IPR001040] 0.3204791118901499 0.0421760429341406 0.9663583605316336 1.0 0.973131900441902 2 P06730 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1e999b9b3cc19edae944e046da25279540d12c00 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S18b, mitochondrial [IPR040054]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3'5'-cyclic nucleotide phosphodiesterase [IPR023088]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abr/Bcr [IPR037769]", "Acetate-CoA ligase [IPR011904]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin filament-associated protein 1 [IPR029907]", "Actin-filament associated protein [IPR030113]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 5 [IPR007239]", "Autophagy-related protein 9 [IPR007241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit RAP80 [IPR038868]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Brain acid soluble protein 1 [IPR008408]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPI-17 [IPR008025]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Copper homeostasis protein CutC [IPR005627]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Costars family [IPR044302]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 1 [IPR014807]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Decaprenyl diphosphate synthase-like [IPR001441]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrodolichyl diphosphate synthase complex subunit Nus1 [IPR038887]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deltex family [IPR039398]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydroorotate dehydrogenase, class 2 [IPR005719]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E2F Family [IPR015633]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongator complex protein 6 [IPR018627]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endosulphine [IPR006760]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ephrin [IPR031328]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 3 [IPR028479]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Family of unknown function DUF5525 [IPR037656]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Folylpolyglutamate synthase, eukaryota [IPR023600]", "Folylpolyglutamate synthetase [IPR001645]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucocorticoid receptor [IPR001409]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucose-methanol-choline oxidoreductase [IPR012132]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HIRA-interacting protein 3 [IPR037647]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "I-BAR domain containing protein MTSS1/MTSS2 [IPR030127]", "I-BAR domain containing protein MTSS2 [IPR030059]", "ICln [IPR003521]", "ING family [IPR028651]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of growth protein 4/5 [IPR028638]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Interleukin-1 receptor-associated kinase 1 [IPR035536]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper protein 1 [IPR026734]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial intermembrane space import and assembly protein 40 [IPR039289]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdenum cofactor sulfurase [IPR028886]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple PDZ domain protein [IPR032078]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 5 [IPR030574]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 6 [IPR037994]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "OPI10 family [IPR031318]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX family [IPR043565]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol 3-kinase, Vps34 type [IPR008290]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-B-cell leukemia transcription factor-interacting protein 1 [IPR033589]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM210A/B-like [IPR045866]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein KTI12/L-seryl-tRNA(Sec) kinase [IPR013641]", "Protein Kti12 [IPR045106]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF4559 [IPR027897]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4660 [IPR029089]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Putative ribosome-binding factor A, mitochondrial [IPR039212]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein Fox-1 [IPR017325]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 33 [IPR039878]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ragulator complex protein LAMTOR3 [IPR015019]", "Ragulator complex protein LAMTOR4 [IPR034601]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L33 [IPR001705]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding factor A [IPR000238]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 12 [IPR034477]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MARK3 [IPR033628]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC gamma-like [IPR039029]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialate O-acetylesterase [IPR039329]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Supervillin [IPR015628]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 1/Shy1 [IPR002994]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Tectonic [IPR040354]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit 2 [IPR006722]", "Trafficking protein particle complex subunit 2-like [IPR044760]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 2 [IPR037813]", "Transcription initiation factor TFIID subunit 5 [IPR037783]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone C [IPR027684]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U4/U6.U5 small nuclear ribonucleoprotein component Snu23 [IPR040107]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1-binding protein 1-like [IPR026728]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vinexin [IPR028510]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat HIR1 [IPR031120]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 47 [IPR040067]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-guanine transglycosylase [IPR004803]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "AKT3", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD31", "BYSL", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf52", "C2CD5", "C2orf49", "C3orf58", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF2", "CENPB", "CENPI", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1L", "CHD8", "CHDH", "CHERP", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COASY", "COG3", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFNB1", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM210B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMDS", "GMFB", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO4", "IPO5", "IQCB1", "IRAK1", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JPT2", "JUP", "KARS", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL14", "METTL16", "METTL3", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTSS1L", "MTX1", "MTX2", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NFRKB", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRM", "NRP1", "NSA2", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUS1", "NUSAP1", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAX6", "PBDC1", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD2", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP1R14B", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM33", "RBM39", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO4", "RFC1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDCCAG3", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLK", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG1", "SMIM12", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPOUT1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF12", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF1", "SURF4", "SURF6", "SVIL", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCC", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCTN3", "TECR", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFRC", "TGFBRAP1", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TLK2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM167A", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBQLN1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UIMC1", "UMPS", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP13", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", 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109.59708737864078 -0.6246385107453618 0.5210365456933685 14.198183528053043 11.00100574670184 1.3356881442801127 0.3736089927477103 1.0 1.0 1.0 0.0499987274757449 0.0013647196758934 +Phosphoribosyltransferase-like [IPR029057] 6 8 2.1991873514334603 0.0278646033455678 4.381067961165049 7.220873786407767 -0.4849811622119724 0.4443743988875169 1.963979224289181 0.76783089612297 1.0082315012212997 0.314953278431846 1.0 1.0 0.1008375048293403 0.2373820829012167 0.0971506673250001 +Armadillo-type fold [IPR016024] 83 173 2.1252674000308307 0.0335643068497035 54.39320388349515 154.9271844660194 -0.7156260328127132 0.5156794927841862 19.860942605814085 17.3539547781392 1.3841368906359015 0.3702561522106249 1.0 1.0 0.9398967132812726 0.0104318895661819 0.0003436004528691 +WW domain superfamily [IPR036020] 5 11 2.0969294502293088 0.0359998210629497 3.405339805825242 9.919902912621358 -0.0858555958656287 0.5637278068566357 2.2797697531221104 2.5468221184832287 0.892206572514041 0.3006643647028539 1.0 1.0 0.0538434207197609 0.0144174128758978 0.0393164024746651 +Prefoldin [IPR009053] 4 5 2.0249870114434585 0.0428686979562704 2.0898058252427183 4.572815533980583 0.5922556317623713 0.4057599047024722 1.2124727846670618 1.0802906993483288 1.0235891073057894 0.3062773561417664 1.0 1.0 1.0 0.0010713621736615 0.0005732271800539 +Protein-tyrosine phosphatase-like [IPR029021] 4 14 2.0136550454298936 0.0440457628825075 3.3762135922330097 9.74757281553398 -0.2401801536762176 0.5610541986052188 2.114838292381251 2.9427166848706903 0.8969489539760671 0.31219801913805 1.0 1.0 0.1163398228410075 0.016092475953857 0.1743861197591294 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 12 17 2.011246210446786 0.0442994569595187 6.240291262135922 14.03883495145631 -0.4795039888326857 0.4962151444390079 3.1264651575198763 1.3911811709582909 0.9660479994455816 0.3305078819132143 1.0 1.0 1.0 0.4040612158985918 0.0794376465838621 +Chromo-like domain superfamily [IPR016197] 4 10 2.010372086022825 0.0443918225725434 3.546116504854369 8.487864077669903 -0.1538801288777041 0.5547248899434332 2.0914317727846217 1.7878631550364168 0.8669578984342349 0.3013647607340537 1.0 1.0 0.2297987482657219 0.1392702662277763 0.14168603717257 +Acyl-CoA N-acyltransferase [IPR016181] 7 10 1.9612474236937925 0.049850167190113 2.5849514563106797 9.300970873786408 0.3026886570520987 0.4824772135374048 1.9004513382103856 1.21347572256257 0.9257996515560925 0.2786861297784554 1.0 1.0 1.0 0.0050285619271962 0.012033886898071 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ca00579f91e7b1b9df7b1ecff190135123338914 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 1011, + "title": "Average number of proteins per term", + "value": 5.101879327398615 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..380d38965568bc88fac007f70b6a2750378351bb --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..283ccb39bb6e1ab3ebfe9d0f41cbc2afaf6a5f40 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,199 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.8218735075788601 3.616623462892063 0.0002984709881979 0.2605134688581384 0.0762920846799132 18 P25788,P25789,P20618,Q99436,P49721,P28072,Q06203,P28070,P60900,P28074,P28066,P49720,P25786 13 +Protein kinase-like domain superfamily [IPR011009] 0.4128367635916104 2.61655322338565 0.0088822515715503 0.9998790429694692 0.1008983858296333 88 Q8IV63,Q99570,P42345,P36507,P33981,Q13043,P24941,Q9HA64,P51617,Q99640,P35790,Q16512,Q16539,P48729,Q00534,P42356,Q02750,Q9H4A3,Q9HBU6,Q13535,Q9P289,Q14012,P17612,Q96KB5,P19525,P31751,P49841,Q8NEB9,O75116,Q13177,P78527,Q13546,Q99986,Q00535,P41240,Q96Q15,Q9UHY1,O95747,Q96SB4,P10398,P19784,O14965,P06493 43 +B30.2/SPRY domain superfamily [IPR043136] 0.6789944767728417 2.281382243499555 0.0225258378334338 0.9999999999008152 0.1423351378100102 11 Q9UBL3 1 +Armadillo-like helical [IPR011989] 0.346577670899436 2.2010871800998646 0.0277298526709326 0.9999999999995506 0.1476725759207245 118 Q6PJG6,Q8TCG1,O75155,O14980,O60518,P30153,O43592,Q99570,P42345,Q13200,Q9HAV4,Q99460,Q5VYK3,P50851,Q92973,Q6SZW1,Q8IUR7,Q96T76,Q96JJ3,P30154,Q8TF05,Q9BTY7,Q9Y678,Q96JX3,Q14738,Q13535,Q9H3U1,P42858,O95373,O75165,P55060,Q9BPX3,Q9BZZ5,O00203,Q6AI08,Q92616,Q7Z4Q2,Q27J81,P78527,O14617,O60684,Q9Y5L0,O60763,P52294,O14981,O15397,Q96Q15,Q9UIA9,Q9UBF2,Q86Y56,Q9Y4B6,P42695,O00505,Q86VP6,Q6NXE6,Q9C0E2,O75122,O60879,Q7Z460 59 +Phosphoribosyltransferase-like [IPR029057] 0.7115748297564803 2.1991873514334603 0.0278646033455678 0.9999999999996094 0.1476725759207245 8 P11172,Q14558,Q06203,O60256,P11908,P60891 6 +Armadillo-type fold [IPR016024] 0.3264037366896101 2.1252674000308307 0.0335643068497035 0.999999999999999 0.163930020410871 173 Q6PJG6,Q9Y6E2,O60518,P30153,O43592,Q13200,P78344,Q5VYK3,Q92973,Q8IUR7,Q96T76,Q9NVH2,Q9Y678,Q96JX3,Q14738,Q53EL6,Q9H3U1,Q9BPX3,Q9UBB6,O60763,Q96Q15,Q86VP6,Q13144,Q9C0E2,Q15051,Q7Z460,Q8TCG1,Q99570,Q5H9R7,Q6SZW1,P42356,Q96JJ3,P30154,Q8TF05,Q13535,Q9HCG8,Q9Y4R8,P42858,P55060,O00203,Q6AI08,Q04637,Q27J81,Q7Z6Z7,Q9UIA9,Q9Y4B6,P55010,O00505,O75122,O60879,P42345,Q13395,Q9HAV4,Q99460,Q8NEB9,Q93008,Q92616,Q7Z4Q2,O14617,O60684,Q9Y5L0,P52294,Q9UBF2,P09960,O75155,O14980,Q9UBQ5,Q5T4S7,P50851,Q9BTY7,Q9H4A4,O95373,O75165,Q9BZZ5,P78527,O14981,O15397,Q86Y56,Q9HAU5,P42695,Q7L1Q6,Q6NXE6,Q9UPU5 83 +WW domain superfamily [IPR036020] 0.6438135657195626 2.0969294502293088 0.0359998210629497 1.0 0.1684991624751953 11 O95817,Q96J02,Q13526,P46934,Q96PU5 5 +Prefoldin [IPR009053] 0.8192982456140505 2.0249870114434585 0.0428686979562704 1.0 0.1805843901407893 5 Q9UHV9,Q9NQP4,O15212,Q99471 4 +Protein-tyrosine phosphatase-like [IPR029021] 0.5859604168870458 2.0136550454298936 0.0440457628825075 1.0 0.1839349697575469 14 Q9UNI6,O60942,Q8NCE2,Q13614 4 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.5496982137955704 2.011246210446786 0.0442994569595187 1.0 0.1839349697575469 17 Q15437,P60981,Q9Y281,P23528,P60983,O95486,O95487,Q14019,Q15436,Q6IBS0,Q13045,Q12792 12 +Chromo-like domain superfamily [IPR016197] 0.6397853334687944 2.010372086022825 0.0443918225725434 1.0 0.1839349697575469 10 Q12873,Q9HC52,O14646,P83916 4 +Acyl-CoA N-acyltransferase [IPR016181] 0.6304210093582869 1.9612474236937925 0.049850167190113 1.0 0.1984193662567097 10 P41227,Q86UY6,O60502,O95251,O14929,Q9H9T3,O95260 7 +PX domain superfamily [IPR036871] 0.6018535427301961 1.9374743354380417 0.0526873876333042 1.0 0.2034898607996394 12 Q96L92,Q15036,O60493,Q9UNH7,O60749,Q13596,A1X283,Q9Y5X3 8 +HSP20-like chaperone [IPR008978] 0.611744832172724 1.9256211074527405 0.0541517011864667 1.0 0.2034898607996394 11 Q9HB71,P04792,Q9Y266,O94966,Q8IVD9,Q96RS6 6 +NAP-like superfamily [IPR037231] 0.8323760532242036 1.921191016081965 0.0547076303619373 1.0 0.2034898607996394 4 Q01105,Q99733 2 +PIN-like domain superfamily [IPR029060] 0.7882721394407048 1.89393532145361 0.0582335954274544 1.0 0.2095166013421937 5 Q9Y2L1,Q9UQ84,Q96EK7 3 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.6798900747189116 1.835775342664384 0.0663908896462717 1.0 0.2298670870971941 7 O60343,Q66K14,Q8TC07,Q9NVG8 4 +Death-like domain superfamily [IPR011029] 0.6765444292549673 1.8198177416234191 0.0687867649944298 1.0 0.2349439844911099 7 Q12955,Q13546,O95999,P98170 4 +14-3-3 domain superfamily [IPR036815] 0.7130739982451005 1.7945239204549257 0.072729584127241 1.0 0.2447649265054194 6 Q04917,P61981,P27348,P63104,P31946 5 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.6703289396348417 1.7901127422580114 0.0734357887562169 1.0 0.2458396769289248 7 Q13535,P42356,Q96Q15 3 +HECT, E3 ligase catalytic domain [IPR035983] 0.5600663048015376 1.7813876417148788 0.0748491457311173 1.0 0.2497441793206588 13 Q8IYU2,Q96J02,Q15386,Q7Z6Z7,P46934,Q96PU5 6 +HAD superfamily [IPR023214] 0.4905214123452949 1.7291498744672569 0.0837822748439807 1.0 0.2665198946283748 20 Q969T7,P34913 2 +HAD-like superfamily [IPR036412] 0.4905214123452949 1.7291498744672569 0.0837822748439807 1.0 0.2665198946283748 20 Q969T7,P34913 2 +High mobility group box domain superfamily [IPR036910] 0.5505050664553864 1.7264309723901488 0.0842699077177533 1.0 0.2665198946283748 13 P09429,O15347,Q08945,Q12873,O96028,Q00059 6 +NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096] 0.9024247735904192 1.724284954204665 0.0846564140970651 1.0 0.2666281453337472 2 O43617 1 +HSP40/DnaJ peptide-binding [IPR008971] 0.744871828250133 1.7081113656662814 0.0876156803865466 1.0 0.2742397921696553 5 P25685,O60884 2 +Class I glutamine amidotransferase-like [IPR029062] 0.6055880532374585 1.669247356891574 0.0950683683628912 1.0 0.2939269737458196 8 P49915,Q9NRF8,P17812 3 +Initiation factor 2B-like, C-terminal [IPR042529] 0.7673964887688096 1.6513192001468655 0.0986734137768423 1.0 0.3022994585708716 4 P49770,Q9BV20 2 +Profilin superfamily [IPR036140] 0.8816827344434759 1.6377613549839911 0.1014714860278738 1.0 0.3045809222645723 2 P07737 1 +UBA-like superfamily [IPR009060] 0.453621523670319 1.6322590918165856 0.102624917093002 1.0 0.3060963959865863 24 O94888,Q04323,Q92995,Q14157,Q96RU2,Q5T6F2,P54727,Q9H1I8,P54725,Q7Z6Z7,Q96GG9 11 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3284457799609411 1.5616502113630863 0.1183704138683283 1.0 0.3259392324581112 89 Q13325,Q5VZ89,P42345,Q5R3I4,P33981,P61201,Q15008,P49321,P53041,Q86YR5,Q9BXJ9,Q13535,Q96EK5,A0AVF1,O75153,P31948,Q15785,Q99615,Q99614,O00170,Q6DKK2,Q92791,Q9Y262,Q9Y3D6,Q6P2P2,O76094,O43242 27 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.3259392324581112 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Tubulin, C-terminal [IPR023123] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.3259392324581112 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.3259392324581112 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +CAP Gly-rich domain superfamily [IPR036859] 0.7445191464484158 1.5551507369706816 0.1199101737047305 1.0 0.3259392324581112 4 Q15813,Q99426,Q14203 3 +Translin, C-terminal [IPR016069] 0.8609406952965295 1.5510181209066844 0.1208973414162133 1.0 0.3259392324581112 2 Q15631 1 +Translin, N-terminal [IPR016068] 0.8609406952965295 1.5510181209066844 0.1208973414162133 1.0 0.3259392324581112 2 Q15631 1 +Translin superfamily [IPR036081] 0.8609406952965295 1.5510181209066844 0.1208973414162133 1.0 0.3259392324581112 2 Q15631 1 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.4599246565351618 1.522591409237489 0.127860960391525 1.0 0.3362369675166823 20 Q9UBL3 1 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.8533450189891996 1.5192168580257788 0.1287079193164748 1.0 0.3362369675166823 2 Q04760 1 +EB1, C-terminal domain superfamily [IPR036133] 0.8498393222319669 1.5045352885462846 0.1324435942025292 1.0 0.3427764531588761 2 Q15555 1 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.3515922085464912 6 Q15437,Q15436,O95486 3 +Gelsolin-like domain superfamily [IPR036180] 0.6455888068207352 1.4856645352132254 0.1373678757426943 1.0 0.3515922085464912 6 Q15437,Q15436,O95486 3 +C2 domain superfamily [IPR035892] 0.4111509610676292 1.4663218518849732 0.1425606250634616 1.0 0.3541702773993911 27 Q86YQ8,P46934,Q96HP0,Q96J02,Q16512,Q96PU5 6 +MIT domain superfamily [IPR036181] 0.848042080654593 1.4432803351777748 0.1489415170388304 1.0 0.3646001785139408 3 Q9UN37,Q8N0X7 2 +Tautomerase/MIF superfamily [IPR014347] 0.8340636868244257 1.4384545034654566 0.1503051375826967 1.0 0.3670495026475999 2 P30046 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.3597378019073524 1.4250587052496626 0.1541402321834821 1.0 0.3676335266432812 38 Q9HCE5,Q7Z4G4,Q9NXH9,O60678,Q9UBP6,Q6P2P2,Q9HBK9,Q86X55,Q9BV86,Q8IZ69,Q96P11 11 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.82267017236343 1.390738250516835 0.1643048140249112 1.0 0.3855174086317609 2 O43924 1 +Gamma-glutamyl cyclotransferase-like superfamily [IPR036568] 0.821793748174124 1.3870688446519144 0.1654207710950723 1.0 0.3855174086317609 2 Q8WUX2 1 +Nucleoside phosphorylase superfamily [IPR035994] 0.8215016067776933 1.3858457551124714 0.1657940075434263 1.0 0.3855174086317609 2 Q13126 1 +XPC-binding domain superfamily [IPR036353] 0.8191644756061984 1.376061922443628 0.1688024629957465 1.0 0.3855881113670306 2 P54725 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.8188723342097622 1.3748390601324136 0.1691813455305415 1.0 0.3855881113670306 2 Q9BYT8 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.698675895355889 1.3612767745765133 0.1734262398071213 1.0 0.3879069213384949 4 Q9BRT9 1 +BSD domain superfamily [IPR035925] 0.8127373648846175 1.3491659369210782 0.1772836731467508 1.0 0.3930565648056253 2 Q9NW68 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.6078327263349407 1.310659343049354 0.189972880425834 1.0 0.4077761828248795 6 Q5TAX3 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.8109457151107637 1.2986455781918953 0.1940655886647841 1.0 0.412185525504405 3 O60884 1 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.5049063054513907 1.2833260580492636 0.1993778670430224 1.0 0.4190140223984153 10 Q93034,Q9UPT5,Q8IYI6,Q9UID3,Q86Y37 5 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.7952088810984553 1.2759177142750913 0.2019846084059482 1.0 0.4190715325304354 2 O60841 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.6775207885716287 1.2715716815949305 0.2035253436918336 1.0 0.4190715325304354 4 Q15437,Q15436 2 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.7943083237754776 1.2338942449288812 0.2172423143248831 1.0 0.4375139039491172 3 Q9BYT8 1 +Translation initiation factor IF2/IF5, N-terminal [IPR016189] 0.7730061349693375 1.1834914083832058 0.236614449545458 1.0 0.4663103479346162 2 P55010 1 +Translation initiation factor IF2/IF5, zinc-binding [IPR016190] 0.7730061349693375 1.1834914083832058 0.236614449545458 1.0 0.4663103479346162 2 P55010 1 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.4955212053581629 1.18188667040984 0.237250671682192 1.0 0.4666545312659458 9 Q9C0C9,P49427,Q16763,P68036 4 +NagB/RpiA transferase-like [IPR037171] 0.5417037979574292 1.1629122250197157 0.2448651168806299 1.0 0.4733434668572025 7 Q9BV20,P49770,O95336,Q14232 4 +Inosine triphosphate pyrophosphatase-like [IPR029001] 0.7671633070406242 1.1592620998377177 0.2463493654119801 1.0 0.4753038328845648 2 Q96M27 1 +Helix hairpin bin domain superfamily [IPR029012] 0.7665790242477502 1.156841741994145 0.2473370242004564 1.0 0.4763004408888789 2 Q9ULR0 1 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.489943489928815 1.1518131332245451 0.249397869916536 1.0 0.479355981911821 9 Q9UJY5,Q9UBF2,Q9Y678,O94973,O43747 5 +Nucleoside diphosphate kinase-like domain superfamily [IPR036850] 0.6415672346882815 1.1194086929605689 0.2629658241000951 1.0 0.4878136663581582 4 P15531 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.4986542634747049 1.1140283421896702 0.2652670279355016 1.0 0.4911812550234288 8 P07437,Q9BUF5,Q9BVA1,P04350 4 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.6360447213130983 1.0961241231087908 0.2730244591439146 1.0 0.4991459822685311 4 Q96G03 1 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.6360447213130983 1.0961241231087908 0.2730244591439146 1.0 0.4991459822685311 4 Q96G03 1 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.4025418209856051 1.083195833719691 0.2787215086142924 1.0 0.5059020560306099 18 O14981,Q9H4L7,Q14527,Q12873,O14646,Q9Y620 6 +Mitochondrial carrier domain superfamily [IPR023395] 0.3828916958020528 1.0793706278461552 0.2804225392554853 1.0 0.5080078288836174 23 O43772 1 +Histidine phosphatase superfamily [IPR029033] 0.557536974217523 1.0772040775746814 0.2813891040304903 1.0 0.5080078288836174 6 Q9NQ88,Q9NPH0 2 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.7449605609114869 1.0676769366407295 0.2856662654088406 1.0 0.5138729807848365 2 Q9Y678 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.7303534910896957 1.0079519586048704 0.3134775260230378 1.0 0.5362534328414403 2 Q9UBT2 1 +AH/BAR domain superfamily [IPR027267] 0.4160409460825411 0.9981496327942964 0.3182068057228158 1.0 0.5415944117605501 14 Q9UNF0,Q9UNH7,O60749,Q13596,Q9UQB8,Q9Y5X3 6 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.6082252425887235 0.9794860680965576 0.3273398690825169 1.0 0.553412387361914 4 Q9BXS5 1 +Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502] 0.720712825007302 0.9688197135901012 0.332635148918571 1.0 0.5567783701269459 2 P09960 1 +START-like domain superfamily [IPR023393] 0.572064023494788 0.95441715875115 0.3398725241126268 1.0 0.5679522675667201 5 Q00169,O95433 2 +Metal-dependent hydrolase [IPR032466] 0.5687048223364777 0.9399541135233904 0.3472410983129703 1.0 0.5698959778385086 5 Q01433,Q16555,Q14195 3 +Nucleic acid-binding, OB-fold [IPR012340] 0.2994925201313836 0.9352912411133294 0.3496382279825503 1.0 0.5708772933053258 43 O60942,P16989,P62917,P35244,Q04837,Q9Y2L1,P62266,P15927,P63241,P67809,P33991,P18858,O43776 13 +Moesin tail domain superfamily [IPR008954] 0.7142022209234368 0.9262861120278209 0.3542973113615595 1.0 0.5758755334188692 3 P15311,P26038 2 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.7136905815697505 0.9243591255695984 0.3552993684872438 1.0 0.5765773058436654 3 P42356 1 +eRF1, domain 2 superfamily [IPR042226] 0.7081507449605611 0.9182299182832996 0.3584985085301424 1.0 0.5784693648765006 2 P62495 1 +BAG domain superfamily [IPR036533] 0.7116418574323677 0.916649811906388 0.3593261732368371 1.0 0.5784693648765006 3 O95817 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.4901524163680173 0.911279277024399 0.3621482424074558 1.0 0.580240686329537 7 P09960,Q6P179 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.4901524163680173 0.911279277024399 0.3621482424074558 1.0 0.580240686329537 7 P09960,Q6P179 2 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.4892425369224036 0.9068897427717936 0.3644651058663841 1.0 0.5819576798804851 7 Q4G0X4,Q9NXV2,P63208 3 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.7002629272568077 0.8867261222231335 0.3752263708922703 1.0 0.5881455208869538 2 P29692 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.7002629272568077 0.8867261222231335 0.3752263708922703 1.0 0.5881455208869538 2 P29692 1 +Ribosomal protein P1/P2, N-terminal domain [IPR038716] 0.6985100788781848 0.8797551678241021 0.3789919562722827 1.0 0.5912976354803671 2 P05387 1 +DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921] 0.5542211886258586 0.8779353422221872 0.3799788082706183 1.0 0.591923844624954 5 P40938,P40937 2 +HIT-like superfamily [IPR036265] 0.6991579665008552 0.8699227240722849 0.3843426360607367 1.0 0.5959668789224 3 Q96C86 1 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.6951553709370661 0.8550385853665126 0.3925297870498254 1.0 0.6033090647181949 3 P62847 1 +FERM superfamily, second domain [IPR035963] 0.408318378230755 0.8446307213652192 0.3983170508061384 1.0 0.6101493005530393 12 P26038,Q96AC1,P15311,Q9Y4F1,Q9Y2J2 5 +Proteasome activator superfamily [IPR036252] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.6333170567416488 3 Q9UL46,P61289 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.6333170567416488 3 Q9UL46,P61289 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.68293395675044 0.8099178317698399 0.4179874025020891 1.0 0.6333170567416488 3 Q9UL46,P61289 2 +TGS-like [IPR012676] 0.4688109910441485 0.8091083722087532 0.418452812960852 1.0 0.6333170567416488 7 Q9NTK5,P55039,A2RTX5 3 +Ribokinase-like [IPR029056] 0.6817650496785479 0.8056296821478455 0.4204564056275433 1.0 0.6338437313365191 3 Q9BRR6,P55263 2 +Pseudouridine synthase, catalytic domain superfamily [IPR020103] 0.5370414824711633 0.80523922424008 0.42068164562493 1.0 0.6338437313365191 5 Q96PZ0,Q8WWH5 2 +Chaperone J-domain superfamily [IPR036869] 0.3571685554712804 0.7880868377560316 0.4306459136261407 1.0 0.6412121040884069 18 O75165,Q99543,O60884,O75937,P25685,Q99615,P31689,Q8WXX5,O75190 9 +MoaB/Mog-like domain superfamily [IPR036425] 0.6722173531989488 0.7766818707411366 0.4373464854517577 1.0 0.6483244820993065 2 Q9NQX3 1 +Metal-dependent hydrolase, composite domain superfamily [IPR011059] 0.5557431706728047 0.7646198332271777 0.4444979555434001 1.0 0.6548974654062211 4 Q16555,Q14195 2 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4150297995299575 0.7541267097469251 0.4507731404914485 1.0 0.6595248119201946 9 Q6SZW1,Q9Y6Y8,Q12800 3 +Winged helix DNA-binding domain superfamily [IPR036390] 0.2745740735368688 0.7516991201765404 0.4522320196349485 1.0 0.6606267077064459 48 Q93034,P60228,Q9UBQ5,Q9UNM6,O00716,P61201,P15927,Q15008,Q4G0J3,P85037,Q6PKG0,Q8N3C0,O00232,P39019,P05455,Q9UQ80,P55199,Q9Y285,Q9UNS2,P13984,O43242 21 +Translation protein SH3-like domain superfamily [IPR008991] 0.4263299264032994 0.7435067334934189 0.4571749463858812 1.0 0.6643075686938087 8 P63241,P46778,P62917,O00267 4 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0.5362987791345379 0.687763301837554 0.4916018495527687 1.0 0.6893335227432027 4 P52294,O60684 2 +Metallo-dependent phosphatase-like [IPR029052] 0.412919426838065 0.6774448184539005 0.4981237702432421 1.0 0.6965685720754324 8 Q9BRF8 1 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.4657368472698434 0.6640490708626514 0.5066589047459884 1.0 0.7016878804084853 6 Q9UBF2,Q9Y678 2 +TBP domain superfamily [IPR012295] 0.4657368472698434 0.6640490708626514 0.5066589047459884 1.0 0.7016878804084853 6 Q9UBF2,Q9Y678 2 +PH-like domain superfamily [IPR011993] 0.2514773765317011 0.6601072587928551 0.5091850008505183 1.0 0.703259611830429 69 P26038,P15311,Q12756,Q0IIM8,P50851,Q96JJ3,P50570,Q08945,Q9Y5B9,Q9H6Z4,Q15036,Q96AC1,Q9Y4F1,Q9Y2J2,Q9H4L5,Q9H8V3,P31751,O75116,P11274,P35241,O60343,Q8N8S7,Q13614,Q9Y217,Q8IYI6,Q96TA1,Q86X55,Q66K14,Q9NPI6 29 +Longin-like domain superfamily [IPR011012] 0.3650582617850902 0.6532838100824916 0.5135733278088666 1.0 0.70678556099271 13 Q9BXS5,Q9Y296,P61923,Q92572 4 +Nucleotidyltransferase superfamily [IPR043519] 0.4347431708060391 0.6507104887520199 0.5152333911489884 1.0 0.70678556099271 7 Q5TAX3 1 +F-actin capping protein, alpha subunit, domain 1 [IPR042489] 0.6348232544551644 0.6361233663541203 0.5246960167513768 1.0 0.7119543658632377 2 P47755 1 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.633654688869419 0.6318699626000973 0.5274718524567683 1.0 0.7119543658632377 2 P13984 1 +Peptidase S8/S53 domain superfamily [IPR036852] 0.6330704060765482 0.6297467873825391 0.5288602658390618 1.0 0.7119543658632377 2 O14773 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.6285797779076577 0.6168624287671912 0.5373254702724712 1.0 0.7173275502412272 3 O15355,Q9H0C8 2 +Leucine-rich repeat domain superfamily [IPR032675] 0.2841225878059658 0.6069584624240496 0.5438784784736248 1.0 0.7197135363047574 30 Q15435,Q92688,P39687 3 +CH domain superfamily [IPR036872] 0.2915364282419312 0.5916080644065866 0.554113072402806 1.0 0.7244348952788776 28 Q15555,Q15417,Q86VS8,Q99439 4 +PABC (PABP) domain [IPR036053] 0.6201052016364628 0.5881711420964919 0.5564174251842267 1.0 0.7244348952788776 3 Q13310,P11940 2 +von Willebrand factor A-like domain superfamily [IPR036465] 0.3243652137309327 0.585754211152281 0.5580406980949018 1.0 0.7244348952788776 18 Q86YQ8,Q15437,Q9NWV8,O95486,O95487,Q15436,A3KMH1 7 +Aldolase-type TIM barrel [IPR013785] 0.3283264917925146 0.584640912791308 0.5587891918829604 1.0 0.7244348952788776 16 Q9P2T1,P43490,P37837 3 +FF domain superfamily [IPR036517] 0.6178790534618921 0.5754084457164985 0.5650150935492673 1.0 0.7276818593354257 2 O75400 1 +Ubiquitin-activating enzyme [IPR035985] 0.377027978159468 0.5639354581547046 0.5727980575372651 1.0 0.7330365014812342 9 Q9GZZ9,Q9UBE0 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3013733380493309 0.5086836577438635 0.610973979156447 1.0 0.7673225999095253 22 P42771,O75832,Q9BQG2 3 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.5894319447368872 0.4884029022131951 0.6252644865907762 1.0 0.7746843087540131 3 Q969Y2 1 +NADP-dependent oxidoreductase domain superfamily [IPR036812] 0.4790996784566081 0.4757327578998198 0.6342647802082824 1.0 0.7836223629789283 4 P15121,P48507,P14550 3 +Pyruvate kinase-like, insert domain superfamily [IPR011037] 0.4772875399016868 0.4694534512911002 0.6387455497836461 1.0 0.7865672969930161 4 P14618,Q969Z3 2 +GYF-like domain superfamily [IPR035445] 0.5819893688521053 0.4652726401123642 0.6417362252174985 1.0 0.7878213225307359 3 O75165 1 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.5818234950321384 0.46476235131556 0.6421016515977511 1.0 0.7878213225307359 3 P52907,P47755 2 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.5818234950321384 0.46476235131556 0.6421016515977511 1.0 0.7878213225307359 3 P52907,P47755 2 +Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098] 0.5797779076563303 0.4584884674652853 0.6466015460624701 1.0 0.7899554229114263 3 Q15814,Q01518 2 +PurM-like, C-terminal domain superfamily [IPR036676] 0.5796117739373133 0.4579804885673872 0.6469664591203372 1.0 0.7899554229114263 3 P49903 1 +PurM-like, N-terminal domain superfamily [IPR036921] 0.5796117739373133 0.4579804885673872 0.6469664591203372 1.0 0.7899554229114263 3 P49903 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7906132732339936 2 Q16706 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7906132732339936 2 Q16706 1 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7906132732339936 2 Q16706 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.7906132732339936 2 Q16706 1 +Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223] 0.5796085305287861 0.4469932640194693 0.6548799234460856 1.0 0.792637479238304 2 Q01518 1 +Endonuclease/exonuclease/phosphatase superfamily [IPR036691] 0.4452610561286771 0.4451500281106542 0.6562113370666074 1.0 0.792637479238304 5 Q01968,P27695 2 +Mib/herc2 domain superfamily [IPR037252] 0.5790242477359102 0.4451392032304994 0.6562191593693971 1.0 0.792637479238304 2 Q9ULT8 1 +SUI1 domain superfamily [IPR036877] 0.577855682150169 0.4414415249317441 0.6588933857955368 1.0 0.793551367409561 2 O43583 1 +Rap/Ran-GAP superfamily [IPR035974] 0.5769792579608594 0.4386774518267062 0.660895267456153 1.0 0.794488841139323 2 Q96FS4 1 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.3084536959883509 0.4340999406552644 0.664215868591902 1.0 0.7965862908023877 15 P26038,Q9H3P7,P15311,Q9Y4F1,Q9Y2J2 5 +DNA polymerase family B, thumb domain [IPR042087] 0.5599064874342381 0.399465624132009 0.6895501481803037 1.0 0.816499871166514 3 Q07864,P28340 2 +DNA polymerase, palm domain superfamily [IPR023211] 0.5599064874342381 0.399465624132009 0.6895501481803037 1.0 0.816499871166514 3 Q07864,P28340 2 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.5623721881390709 0.3938065317167654 0.6937238816946745 1.0 0.818383715744826 2 Q9BSJ2 1 +RmlC-like cupin domain superfamily [IPR011051] 0.429089775995518 0.3893094553623187 0.6970472425920342 1.0 0.819435770070403 5 Q96SZ5,P34949 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.5565293602103538 0.3765157281440981 0.7065335249295988 1.0 0.8261585344496288 2 Q9UEY8 1 +ENTH/VHS [IPR008942] 0.2967754224052262 0.3760876129552528 0.7068517629069524 1.0 0.8261585344496288 15 Q92783,Q9UJY5,Q96P16,Q14677 4 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.2849513365710913 0.3673012339425888 0.7133943337646969 1.0 0.830361968622709 18 P24534,Q8NEC7,P26641,O00299,P26640,P28161,P21266,P78417 8 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.830361968622709 2 P42224 1 +STAT transcription factor, coiled coil [IPR015988] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.830361968622709 2 P42224 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.830361968622709 2 P42224 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.4448938094915581 0.362997275275787 0.7166069197275748 1.0 0.8308366924823145 4 O95831 1 +Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864] 0.2855200195143685 0.3542521456484405 0.7231499274787623 1.0 0.8365040923123899 16 Q9Y285,P26639,P49591,P50747,A2RTX5,O43776 6 +Phosphofructokinase superfamily [IPR035966] 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.840861862984832 3 P08237 1 +TFIIS/LEDGF domain superfamily [IPR035441] 0.3808302179891121 0.3330709825383204 0.7390807025992976 1.0 0.8484308013752272 6 Q7Z4V5,Q14241 2 +Beta-grasp domain superfamily [IPR012675] 0.3300879824282627 0.3123889286991567 0.754744963297582 1.0 0.862200178411136 8 Q9NTK5,P55039,A2RTX5 3 +SH3-like domain superfamily [IPR036028] 0.229641748718701 0.3101947951599795 0.7564128283222056 1.0 0.863130213807844 39 P46109,Q92783,Q9UNF0,Q9UQB8,P46108,A1X283,O60504 7 +Vps16, C-terminal domain superfamily [IPR038132] 0.5305287759275632 0.304489511441737 0.7607549822997932 1.0 0.8661298278210483 2 Q9H269 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.2639894553836315 0.3030353068863656 0.7618629548574414 1.0 0.8664155763339406 22 P00390,Q6QHF9,Q9UHG3,Q9H9P8,O95831 5 +K homology domain-like, alpha/beta [IPR015946] 0.5111840218896808 0.2715210583431333 0.7859903056115121 1.0 0.8898501668233356 3 P23396 1 +Translation protein, beta-barrel domain superfamily [IPR009000] 0.258261668496698 0.2571822336108609 0.7970380983676877 1.0 0.898405556104804 20 O60841,Q9BTE6,P39023,P13639,P46199,Q9Y450,Q96HR8,Q05639 8 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.898405556104804 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.898405556104804 2 P22314 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.5109553023663609 0.2559488986890276 0.7979902961247418 1.0 0.898405556104804 2 P22314 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.2227233976744492 0.2144824096549966 0.8301708828608791 1.0 0.925361369980539 30 Q01804,Q96K76,Q96FW1,Q92995,Q96RU2,P40818,Q93008,Q13107,O94966 9 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.3134955742234024 0.190549131587695 0.8488788469291979 1.0 0.9369175919709816 7 O95714,Q9UII4,Q9P258,O95071,O75592 5 +ATPase, nucleotide binding domain [IPR043129] 0.2391114298950173 0.1856128879533476 0.8527483460748055 1.0 0.9401620260432152 21 Q9UJ70,Q9Y223,Q9NVE7,Q9NZ32,Q9NPF4 5 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.3524425724701623 0.1735946016263246 0.8621840748839402 1.0 0.9428289856301264 5 Q9Y450,Q05639 2 +Calpain large subunit, domain III superfamily [IPR036213] 0.4639205375401887 0.160949205683244 0.8721334069315505 1.0 0.9485059781290556 2 P17655 1 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.3158818367943752 0.1493747951079379 0.8812578991722839 1.0 0.9549321929937612 6 Q9P2J5,P26640,P41252,Q15031,Q9NSE4 5 +SH2 domain superfamily [IPR036860] 0.2436550823189099 0.1463254060455469 0.8836645105853131 1.0 0.956514796789884 14 P46108,P46109 2 +Glutamine synthetase/guanido kinase, catalytic domain [IPR014746] 0.3525163109775553 0.1363883940518733 0.8915142481489822 1.0 0.9629496846993814 4 P12277 1 +Creatinase/aminopeptidase-like [IPR036005] 0.293569255741514 0.1047241599291455 0.9165946905211536 1.0 0.9795742411383576 6 Q9Y5B9,Q9UQ80 2 +MutS, connector domain superfamily [IPR036678] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9827004108581888 3 P52701,P43246 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9827004108581888 3 P52701,P43246 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9827004108581888 3 P52701,P43246 2 +Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163] 0.2627267407840846 0.0787219233472336 0.937253807283561 1.0 0.9881588910012968 7 Q9BTE6,P26639,Q9NYK5,P49588,Q5JTZ9,A2RTX5 6 +Ribosomal protein L2, domain 2 [IPR014722] 0.2345929154513347 0.0784930695069463 0.9374358429475208 1.0 0.9881588910012968 10 P63241,O00267,P62701,P62917 4 +K Homology domain, type 1 superfamily [IPR036612] 0.1962688350990608 0.0781222080186281 0.9377308417345483 1.0 0.9881588910012968 26 Q9Y6M1,Q96AE4 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.3857824556512375 0.0738826724561498 0.941103743538946 1.0 0.9881588910012968 3 Q9UNN8 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.3857824556512375 0.0738826724561498 0.941103743538946 1.0 0.9881588910012968 3 Q9UNN8 1 +GHMP kinase, C-terminal domain superfamily [IPR036554] 0.3825248392752745 0.0712508017590643 0.9431981501644426 1.0 0.9881588910012968 3 Q03426,P51570 2 +Histone deacetylase domain superfamily [IPR037138] 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9883804538254358 3 O15379,Q92769 2 +Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149] 0.2968810973865465 0.0635781294354153 0.9493061466848308 1.0 0.9892881673476664 4 Q9Y5B9 1 +Cullin homology domain superfamily [IPR036317] 0.2527794031597389 0.063460316541133 0.94939995833263 1.0 0.9892881673476664 7 Q93034,Q9UJX6,Q13620,Q13618,Q13616,Q13617 6 +SMAD/FHA domain superfamily [IPR008984] 0.2073766954764457 0.0625219389126981 0.9501471913893018 1.0 0.9892881673476664 14 P85037,Q5SW79 2 +Ribosomal protein L10-like domain superfamily [IPR043141] 0.3571011104617182 0.0542595339664898 0.95672838924958 1.0 0.9910372966509484 3 P05388,Q7Z7H8 2 +Dbl homology (DH) domain superfamily [IPR035899] 0.2207259953161584 0.0442309179913357 0.964720337169272 1.0 0.9940145990454592 9 Q92974,Q92888,P11274,Q9Y4F1,Q12802,Q9H8V3,Q14155,Q9NZM3 8 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.3204791118901499 0.0421760429341406 0.9663583605316336 1.0 0.9940145990454592 2 P06730 1 +Ribosomal L18e/L15P superfamily [IPR036227] 0.323202805376975 0.039888128057843 0.9681823160089824 1.0 0.9940145990454592 3 Q07020,P46776 2 +Arp2/3 complex subunit 2/4 [IPR034666] 0.2845457201285348 0.0370946511430008 0.9704095368645712 1.0 0.9940145990454592 2 O15144 1 +Mss4-like superfamily [IPR011057] 0.2655565293602018 0.035851193565676 0.9714010127170264 1.0 0.9940145990454592 2 P13693 1 +ESCRT assembly domain [IPR037202] 0.2413793103448329 0.0282180465246002 0.977488243909852 1.0 0.9982228430230914 3 Q9H9H4,Q99816 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..80e60fafad51d1c53df4795c9c8735ccf6e7cab4 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily [IPR036971]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Autophagy protein Atg5, UblA domain [IPR042527]", "Autophagy protein Atg5, helix rich domain [IPR042526]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CPI-17 superfamily [IPR036658]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper homeostasis (CutC) domain superfamily [IPR036822]", "Costars domain superfamily [IPR038095]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Decaprenyl diphosphate synthase-like superfamily [IPR036424]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deltex, C-terminal domain superfamily [IPR039399]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E2F-DP heterodimerization region [IPR037241]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "Mur ligase, C-terminal domain superfamily [IPR036615]", "Mur-like, catalytic domain superfamily [IPR036565]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAS domain superfamily [IPR035965]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L33 superfamily [IPR038584]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribosome-binding factor A domain superfamily [IPR023799]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TBCC, N-terminal domain superfamily [IPR038397]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIID subunit TAF5, NTD2 domain superfamily [IPR037264]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Villin headpiece domain superfamily [IPR036886]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRACL", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATR", "ATRX", "ATXN10", "ATXN2", "AURKA", "AURKB", "B3GAT3", "B4GALT3", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCKDHA", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA7", "COASY", "COG8", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT3", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTI12", "KYAT3", "L2HGDH", "LACTB", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDZ", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUS1", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAX6", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIAS1", "PICALM", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSPRY1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERAC1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIAE", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMS", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX4", "STX5", "STX7", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WDHD1", "WDR1", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZNF280C", "ZNF281", "ZNF292", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS", "AARS2", "AARSD1", "ACBD3", "ACP6", "ACTR10", "ADD3", "ADK", "ADO", "ADPGK", "AHSA1", "AIFM1", "AIP", "AKAP13", "AKR1A1", "AKR1B1", "AKT2", "AMPD2", "ANAPC2", "ANK3", "ANP32A", "ANP32B", "AP1G1", "AP1M1", "AP2A2", "AP3B1", "AP3D1", "AP3S1", "APEX1", "API5", "ARAF", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARMC6", "ARMC8", "ARPC2", "AS3MT", "ASCC2", "ASCC3", "ASH2L", "ATE1", "ATR", "AURKA", "BABAM1", "BAG3", "BAIAP2", "BCL10", "BCR", "BRAT1", "BSDC1", "BTAF1", "BZW1", "BZW2", "CACUL1", "CACYBP", "CAMK1", "CAND1", "CAND2", "CAP1", "CAPN2", "CAPZA1", "CAPZA2", "CARM1", "CBX1", "CBX8", "CDC34", "CDK1", "CDK2", "CDK5", "CDK6", "CDKN2A", "CEP170", "CFL1", "CFL2", "CHAC2", "CHD1", "CHD3", "CHKA", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLINT1", "CLUH", "CNN2", "CNN3", "COPG1", "COPG2", "COPS2", "COPS3", "COPZ1", "COTL1", "CPNE8", "CPPED1", "CRK", "CRKL", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CTPS1", "CTPS2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "DCAF1", "DCP1A", "DCPS", "DCTN1", "DCUN1D1", "DDT", "DENND4C", "DENR", "DIAPH2", "DIS3", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM2", "DOCK6", "DPYSL2", "DPYSL3", "DRG2", "DSTN", "DUSP12", "E2F3", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B5", "EIF3E", "EIF3K", "EIF3L", "EIF4E", "EIF4G1", "EIF4G2", "EIF5", "EIF5A", "EIF5B", "ELL", "ELMO2", "ELOA", "ELP3", "ENAH", "EPB41L3", "EPHX2", "ERAP2", "ETF1", "ETNK1", "EXO1", "EXOC7", "EXOC8", "EZR", "FAM120B", "FAM129B", "FARP1", "FARSA", "FERMT2", "FIS1", "FLII", "FN3KRP", "FOXK1", "FUBP1", "GALK1", "GCLM", "GCN1", "GGA1", "GINS4", "GLO1", "GMFB", "GMPR2", "GMPS", "GNE", "GPHN", "GPSM1", "GSK3B", "GSR", "GSTCD", "GSTM2", "GSTM3", "GSTO1", "GTF2F2", "GTPBP3", "HACE1", "HAT1", "HBS1L", "HDAC2", "HDAC3", "HDGFL2", "HEATR3", "HEATR6", "HECTD1", "HERC2", "HERC5", "HGH1", "HLCS", "HLTF", "HMGB1", "HMGB3", "HOOK3", "HSPB1", "HTT", "HUWE1", "IARS", "IARS2", "IFIT5", "IGF2BP2", "ILKAP", "INF2", "INTS7", "IPO7", "IPO8", "IQCB1", "IRAK1", "ISY1", "ITCH", "ITSN2", "KAT7", "KCTD21", "KCTD5", "KIAA0368", "KIF1A", "KIFBP", "KPNA1", "KPNA3", "KPNA6", "L2HGDH", "LARP1", "LARP7", "LARS", "LARS2", "LIG1", "LRBA", "LTA4H", "MAN2A1", "MAP2K1", "MAP2K2", "MAPK14", "MAPRE2", "MARC2", "MCM4", "METTL1", "METTL14", "MGEA5", "MMS19", "MPI", "MRI1", "MRPL10", "MRPL39", "MSH2", "MSH6", "MSN", "MTAP", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MVK", "MYCBP2", "NAA10", "NAA15", "NAA40", "NAF1", "NAGK", "NAMPT", "NAP1L4", "NARS", "NASP", "NCAPD3", "NCAPG", "NCDN", "NEDD4", "NEDD4L", "NLN", "NME1", "NRBP1", "NSD2", "NSUN5", "NT5C3B", "NTMT1", "NUDC", "NUDCD1", "NUDCD3", "NUDT12", "OCRL", "OLA1", "OSBPL3", "OSGEP", "OTUB1", "OTUD4", "OXSR1", "P3H4", "PA2G4", "PABPC1", "PABPC4", "PACSIN2", "PAK2", "PANK4", "PAOX", "PBK", "PCYOX1", "PDCD4", "PDE6D", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKM", "PFN1", "PGLS", "PGM2", "PI4KA", "PIK3C3", "PIK3R4", "PIN1", "PITPNA", "PKM", "PKMYT1", "PKN1", "POLD1", "POLE", "PPAT", "PPM1G", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6R3", "PRKACA", "PRKDC", "PRMT3", "PRMT9", "PROCR", "PRPF40A", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSMA1", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD1", "PSMD10", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME2", "PSME3", "PUS7", "RAD23A", "RAD23B", "RAD54B", "RANBP3", "RANBP6", "RCC2", "RDX", "RFC3", "RFC5", "RIPK1", "RNGTT", "RNPEP", "ROCK2", "RPA2", "RPA3", "RPL18", "RPL21", "RPL27A", "RPL3", "RPL8", "RPLP0", "RPLP2", "RPRD1A", "RPS19", "RPS23", "RPS24", "RPS3", "RPS4X", "SAE1", "SARM1", "SARS", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEPHS1", "SERAC1", "SET", "SH3PXD2B", "SIPA1", "SKP1", "SLC25A20", "SMARCAD1", "SMG1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SORBS3", "SPART", "SRP72", "SRPK1", "SSB", "SSBP1", "SSRP1", "STAM", "STAT1", "STIP1", "STK26", "STK4", "SUPT16H", "SUPT5H", "TALDO1", "TARBP1", "TARS", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCC", "TBCE", "TELO2", "TFAM", "TFCP2", "TIGAR", "TNPO1", "TNPO3", "TOMM34", "TPP1", "TPT1", "TRAPPC3", "TRAPPC4", "TRMT1", "TRMT11", "TRMT2A", "TRUB1", "TSG101", "TSN", "TTC1", "TTC19", "TTC26", "TTC38", "TTK", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "TUBGCP2", "TWF1", "TWF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2L3", "UBE2O", "UBE2S", "UBE3C", "UBR4", "UBR5", "UBXN1", "UBXN7", "UMPS", "UNC45A", "UPF2", "USO1", "USP13", "USP19", "USP24", "USP28", "USP4", "USP47", "USP8", "USP9X", "VARS1", "VPS16", "VPS37B", "VPS4A", "VPS51", "VRK1", "VRK3", "VWA8", "WNK1", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "YBX1", "YBX3", "YWHAB", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZCCHC11"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5681d1558d0085e1887e9376c549b9710ca5f86e --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c8eaec92aa6f21bb4d719999d1ec7470edd2b144c97ac06d0db62af479b5191 +size 76042 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..02b676fd6453f99a89de142b65ac858ab2a9d756 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.0 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f38be8c2df8c7c68ccc758cafff91384b4013121 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2b321ad0217a9efa2be84d6f2e1cd169fc1052ab --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "EIF5A", "FASN", "LDLR", "LRP1", "SLIT2"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2491541fa641204d02a6eb3b732ff4ab6e8adebc --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "HEAT, type 2 [IPR021133]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..52f6cf366a51e103f6f140a554468c2cfb320f67 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1429680ae1ef06b8537520c3a2ad41b4ca2445f80a03aa470793c42bddfe8885 +size 127134 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..031a69d3599e78633c276362c3b9a2e1f22dbc0c --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:679377314725e9cd3cfb2ae66470f269115b3e3aaab53ae0df796c575ec67d36 +size 152020 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bed675eabb92c05a02058d02381740f4d148ec80 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95a9bbb775140b2c95829c89cdf1d8e15f161901d1eb4a553e4b3f5004e7836d +size 83948 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5c94b8fa5fac1b24dbdc6690278650ceab5a744d --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 83, + "title": "Average number of proteins per term", + "value": 5.493975903614458 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f94087cb5e840209b9fc6940999d938f5135dfdc --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..718e8e86e9245c30e2d0ecbd12af8c7e17f9c927 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,18 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +HEAT, type 2 [IPR021133] 0.5647566600141602 1.8082567259858568 0.0705665535689581 0.9976979293906916 0.2402460414718439 13 P30154,Q99570,P30153,Q8TF05,Q86Y56,Q13535,Q7Z460 7 +HEAT repeat [IPR000357] 0.6203514823584446 1.7446439965139449 0.0810468573639955 0.999101848734708 0.2402460414718439 8 Q6PJG6,Q8TF05,P30154,P30153 4 +Calponin repeat [IPR000557] 0.8399406770703057 1.4116886055693074 0.1580416698465296 0.9999993703203712 0.3747845313503418 3 Q99439 1 +Proteasome/cyclosome repeat [IPR002015] 0.7686240140227915 1.1653150965245302 0.2438914704923396 0.9999999999163468 0.4600680011560042 2 Q13200 1 +Mitochondrial substrate/solute carrier [IPR018108] 0.3828916958020528 1.0793706278461552 0.2804225392554853 0.9999999999986278 0.5068566744184493 23 O43772 1 +Tetratricopeptide repeat [IPR019734] 0.2943434117400442 0.9528838915124112 0.3406489026166275 0.999999999999999 0.5068566744184493 49 Q13325,P31948,Q6DKK2,Q9BXJ9,Q15785,Q99615,Q99614,A0AVF1,O00170,Q6P2P2,Q07866,P49321,O76094,P53041,Q86YR5 15 +Tetratricopeptide repeat 2 [IPR013105] 0.599958262676964 0.9451050746752252 0.3446052348065072 0.9999999999999994 0.5068566744184493 4 Q13325 1 +Leucine-rich repeat [IPR001611] 0.3515865492127195 0.9243710138468252 0.3552931809567023 1.0 0.5084367934380396 25 Q15435,P39687 2 +Hexapeptide repeat [IPR001451] 0.6641955269061419 0.7418166281499264 0.4581984444844256 1.0 0.5834601751889701 3 Q96IJ6 1 +Atypical Arm repeat [IPR032413] 0.5362987791345379 0.687763301837554 0.4916018495527687 1.0 0.6089993061623852 4 P52294,O60684 2 +Leucine rich repeat 4 [IPR025875] 0.6390476015431124 0.6528933989306746 0.5138250048544051 1.0 0.6180793536654438 3 Q9UFC0 1 +Importin repeat 4 [IPR041653] 0.5810692375109654 0.4516435483527484 0.6515257922537572 1.0 0.7307654156359709 2 O60518 1 +Importin repeat 6 [IPR041389] 0.5810692375109654 0.4516435483527484 0.6515257922537572 1.0 0.7307654156359709 2 O60518 1 +Tetratricopeptide repeat 1 [IPR001440] 0.3268989789957779 0.3946243212260349 0.6931201615810829 1.0 0.7670529788163984 11 Q99614,P53041,Q15785 3 +Ankyrin repeat [IPR002110] 0.274134302186225 0.3320040241670222 0.7398862203549743 1.0 0.8080336353876694 20 O75832,Q9BQG2 2 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.3003549176616369 0.1172578726360315 0.9066557074370378 1.0 0.9177124843570016 6 Q9P258 1 +Sel1-like repeat [IPR006597] 0.3301197779725352 0.0444450932966353 0.9645496178876878 1.0 0.9645496178876878 2 Q9UBV2 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b6e5b8023cbfae1910c8bb9d19934bda95ad2e72 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", 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translation 61 116 3.2566116646047125 0.0011275057215649 48.71601941747573 111.8980582524272 -0.8335022906838897 0.3996000903963488 17.644533125121402 3.3960708473896934 1.9604583248560443 0.3879157282634429 1.0 0.4882804103003091 0.3940599353058721 0.0217117445893618 0.0013415742890306 +Secondary alcohol metabolic process 6 46 3.2364852390349124 0.0012101148482595 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 1.0 0.0007227441843529 0.0001822132476349 0.0051798047238881 0.0605451328748618 +Proteasomal protein catabolic process 62 172 2.970707244979006 0.0029711486072925 37.56553398058252 157.79126213592232 0.1135553068650112 0.7570101769480738 14.502195229082991 14.765320210929556 0.8241107661556262 0.3132494806399983 1.0 0.3013261913949993 0.198466834361642 0.0001502491450756 8.495678973186426e-05 +Pyrimidine nucleotide metabolic process 9 18 2.900087452214514 0.0037305856084945 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1.444653995706506 0.7704353439327314 0.2037484924456972 1.0 0.0901405579438761 0.1758008751515455 0.0840389641709933 0.2539261987860491 +Protein dephosphorylation 34 78 2.8078149747985486 0.0049878875665501 16.924757281553397 63.59466019417476 -0.3746605067442632 0.59497085999272 7.528371495102524 9.296009720799146 0.8718728641950716 0.3340788227321948 1.0 0.6325910777230552 0.1434578911288594 0.0006072103643345 0.0067420442038564 +Cellular carbohydrate metabolic process 18 65 2.7862624879856406 0.0053319676251617 12.298543689320388 60.53398058252427 -0.0198217634236293 0.5474782336568482 5.253819490464295 6.177496797185298 1.0012857082474305 0.3337612932793398 1.0 0.2042324090251818 0.0921528133877617 0.0690244222994634 0.0059680827632771 +Cellular response to reactive oxygen species 2 29 2.7766979883118106 0.0054914178398175 6.296116504854369 28.96359223300971 0.1275599752484963 0.5594498682008983 4.232867749467832 3.8124902939539496 0.9960221378122438 0.3189944504766323 1.0 0.0108939889612075 0.0681614338573012 0.4277148969936045 0.5219417768349573 +Stress activated protein kinase signaling cascade 17 43 2.7554576150090795 0.0058610097748919 9.16747572815534 35.592233009708735 0.0363959748886252 0.6968819183055537 5.40887534178808 5.138729572142261 0.7394130543964318 0.3013836593101427 1.0 0.5191611022715147 0.4375150159471063 0.1728211487574672 0.129985402944014 +Negative regulation of transporter activity 7 18 2.7456332942180386 0.0060394227959195 4.111650485436893 13.21359223300971 0.2247815310389012 0.5569194596928818 2.4892312132824013 2.101319444192533 0.8931834718774553 0.3061163348813704 1.0 0.1723099894081314 0.0065760397653667 0.0003737964402907 0.0005743066382168 +Dicarboxylic acid metabolic process 2 45 2.7032121894743337 0.0068672891659267 11.565533980582524 42.76699029126213 -0.0799566329483392 0.5436626350484396 7.364509254493807 2.809325260161498 1.0116379575449843 0.3261188618805979 1.0 0.0042974194252635 0.029653655190088 0.0275014842073337 0.1243087546226736 +Negative regulation of stress activated protein kinase signaling cascade 7 11 2.6557364006212807 0.0079135445472209 3.83495145631068 9.41019417475728 -0.0607437870152996 0.5896640946176641 2.283741978601781 1.2204539029748132 0.8395438390397254 0.2953024296785091 1.0 1.0 0.2802926639431586 0.0089321887950908 0.0231294135439989 +Tricarboxylic acid metabolic process 1 10 2.652623231086845 0.0079868967452174 3.766990291262136 9.388349514563108 -0.367579777657415 0.3202342688769181 2.323179456329947 0.6306570731062863 1.3940148783056183 0.2966527591969329 1.0 0.0013899505248691 0.0056684159955205 0.0331187861076589 0.1129571724371578 +Negative regulation of ion transmembrane transporter activity 6 16 2.636996680468444 0.0083643650108369 3.817961165048544 11.861650485436892 0.3764600221454999 0.5118077234396127 2.3889648646862596 1.939068236399221 0.964288359393085 0.3191649145735881 1.0 1.0 0.0420348553288257 0.0012777259352904 0.0010565154778331 +Pyrimidine nucleoside triphosphate metabolic process 6 12 2.623272279029514 0.0087089642283029 3.2402912621359223 12.305825242718448 0.0506614401496208 0.4888226190049212 2.6980805677588324 1.632100632410349 1.0766912351899522 0.3187660552908488 0.0023538642604679 0.1071891284628969 0.2070995190727305 0.1147066696002357 0.0271057364081029 +Response to axon injury 5 17 2.6100938156683604 0.009051739512746 3.4223300970873787 15.0873786407767 0.4784356131295292 0.5286211208988147 2.0530078354914556 2.3631754024711653 0.7880827580202387 0.2904779371725667 1.0 0.2068720246493716 0.0803922289273931 0.1161428196700428 0.0305407497227627 +Regulation of response to external stimulus 43 141 2.596168090570774 0.0094269934923982 27.32766990291262 129.63349514563106 0.3937649860570471 0.6986677015868525 9.316542933972368 15.399506498758855 0.8616366228871625 0.3591499966721317 1.0 0.0517738906553698 0.0563623421842366 0.170169599189481 0.1098441289949681 +Nucleoside phosphate catabolic process 8 18 2.5927401357956468 0.0095214684185527 4.604368932038835 18.655339805825243 0.0962143819400473 0.5415770686805816 3.4056321626088666 2.256091136153212 0.9847714139711842 0.3121628759754123 0.0060808160061114 0.0343104139968933 0.1194965359594502 0.0171674062949385 0.0798641650837513 +Pyridine containing compound metabolic process 3 9 2.5605185517484057 0.0104516083091128 2.0970873786407767 8.322815533980583 0.4540466222528479 0.4390330236639146 1.3987828489027132 1.368921279996281 0.9633622426855916 0.2728871683799344 1.0 0.0043047615253927 0.0010099703116007 0.0014755138450769 0.0171177319456962 +Response to reactive oxygen species 5 37 2.5556360608859814 0.0105993913402879 6.643203883495145 34.40291262135922 0.3370560023195971 0.5582061055009889 4.209487369013932 4.78801003135187 0.9361306406896482 0.3200560676091487 1.0 0.0249752776964441 0.1382318498722026 0.4117075435355238 0.6405988688065674 +Neuron projection regeneration 4 11 2.5385211154755947 0.0111322084950944 2.3058252427184467 9.79611650485437 0.887202443720293 0.3987106095324453 1.3505356896696743 1.5461145996848544 0.8042022398095918 0.2932545495700766 1.0 0.1524760813950871 0.0443091130960601 0.2089591760219589 0.0259406914165302 +Regulation of stress activated protein kinase signaling cascade 13 32 2.524233698167037 0.0115950817991137 6.951456310679611 27.381067961165048 0.2313650341297954 0.6911021636242265 4.675651952415842 3.759509731675893 0.7215171740138203 0.3097912587256555 1.0 1.0 0.68527292971009 0.1640234719188354 0.1251643841969073 +Deoxyribose phosphate metabolic process 7 12 2.5234280457407263 0.0116216841628498 3.8932038834951457 14.16019417475728 0.2911792764864474 0.4364643181075437 2.7187326479186407 1.955467307187883 1.1552055506656809 0.3084957081652735 0.0033346410356261 0.1484538203623246 0.2802926639431586 0.2000228109389489 0.4978168612908779 +Regulation of jnk cascade 8 15 2.4954678476891927 0.0125791154632541 3.745145631067961 12.730582524271844 0.0342722637181126 0.5856074037040684 2.335999552831812 2.800439745372428 0.865405433051665 0.3027772361459041 1.0 1.0 0.552858073626208 0.3284623958158804 0.2162551994885705 +Isocitrate metabolic process 1 6 2.4705170500835805 0.0134917887221743 2.3276699029126213 5.495145631067961 -0.2061858290398174 0.3041702034210444 1.4604532504880654 0.4999764345469411 1.4464876184642763 0.300957520728341 1.0 0.0003216487357623 0.0013376518177504 0.0082857576662697 0.0310935661517569 +Microtubule anchoring 8 12 2.46755301072038 0.0136040076626682 3.71116504854369 10.444174757281552 0.5813177927378261 0.462294633438152 2.2374941778829167 2.008305581644815 0.8943151809183938 0.3009482581409394 1.0 1.0 1.0 0.1067922158236129 0.0043329575683166 +Alcohol metabolic process 8 90 2.4599272532203167 0.0138965180428496 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 1.0 0.0028863645339563 0.0039375020442376 0.0315978193397554 0.0849675344448974 +2 oxoglutarate metabolic process 2 9 2.4435935669781 0.0145417982752822 3.453883495145631 9.264563106796116 -0.1064110443111423 0.384612626342152 2.2992842841711263 0.7004898101848963 1.2698803823360194 0.3050485324830972 1.0 0.0021914548918381 0.0088504827764808 0.005208827916976 0.0049176108076387 +Retrograde transport endosome to golgi 13 34 2.4388340228652323 0.014734734192831 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 1.0 0.3251409200136808 0.1897338295109766 0.1433163186586668 0.0482032035846316 +Benzene containing compound metabolic process 3 7 2.431644013986502 0.0150304717454792 2.9029126213592233 5.949029126213592 -0.7825533109688244 0.3431264098941031 1.6473842938981933 0.926850826973976 1.0963824746417352 0.2910074998255683 1.0 0.0461123069087121 0.0921025797166938 6.393058955734768e-05 0.000918782674844 +Alpha beta t cell differentiation 5 9 2.412130163298866 0.0158596184386743 3.0145631067961167 10.315533980582524 0.0059961459623565 0.5316576321586325 2.267281326820642 1.2608563341821548 0.931380131474168 0.2953345406530252 1.0 0.1993158438338612 0.3655284832956332 0.3174825468726979 0.193832289989472 +Folic acid metabolic process 1 8 2.407707671398321 0.0160530292660534 1.91747572815534 7.140776699029126 1.2977645388348351 0.249592124826322 1.215987926650751 0.8615786924829095 0.8405378716662024 0.2600707347072601 1.0 0.0639684350193291 0.1265462710440741 0.0442367692127036 0.1462762019757018 +Regulation of early endosome to late endosome transport 9 12 2.3902153810787934 0.0168384947974384 5.206310679611651 11.00728155339806 -0.374414164017723 0.5122504381318619 2.796262932722006 1.8108211376533971 0.917689867011628 0.3084729300443259 1.0 1.0 1.0 0.3582816735878424 0.2173267675800807 +Pyrimidine containing compound metabolic process 12 27 2.388793067306352 0.0169038204020872 8.009708737864077 27.08252427184466 -0.2756045187145757 0.5434059058486369 4.712604757932364 3.4001692472000644 0.9602027857856432 0.3148010159956353 0.0068654374262982 0.2821140734917597 0.4925597827158772 0.2421850656984442 0.2535379185251815 +Regulation of mitochondrial fusion 1 7 2.3876293883015336 0.0169574324758587 1.5242718446601942 4.766990291262136 0.7253550907037913 0.367601169377127 1.0824698493002796 0.7815081697098348 1.0008486659137603 0.2877626014609443 1.0 0.0009534063593398 0.0039135152062846 0.0233125205204954 0.0820486275159116 +Regulation of cellular response to heat 7 10 2.383500700616705 0.0171488518260372 3.121359223300971 7.245145631067961 -0.0991785417157341 0.5552919010383071 1.84596913192154 1.4178476536930384 0.8692286384314623 0.2971906512580883 1.0 1.0 1.0 0.3422564852890665 0.0468003866103798 +Negative regulation of lymphocyte activation 5 17 2.369219616041589 0.0178256651668093 4.754854368932039 15.235436893203884 -0.2061399667415382 0.5738742819371534 2.639432258781139 2.587386609944193 0.8793188648866922 0.3089176121393133 1.0 0.2613604367755145 0.4620800234731917 0.2037122235382634 0.0899947151145778 +Regulation of cytoplasmic transport 9 14 2.3298990955341634 0.0198114848461004 5.334951456310679 13.033980582524272 -0.4149082937766818 0.5201053826715327 3.2071585203015047 1.9179303872916629 0.8969198780140912 0.3128081882154122 1.0 1.0 1.0 0.4600796867443816 0.345186345277882 +T cell receptor signaling pathway 10 19 2.328857716439213 0.0198666045985045 5.757281553398058 20.33252427184466 -0.0343916124669796 0.6098693172568592 3.2619192022324417 2.9892380489831427 0.8231945191955886 0.3022220567849885 1.0 1.0 1.0 0.835361924407007 0.143549387276975 +Antigen receptor mediated signaling pathway 10 20 2.317541919528596 0.0204742298904263 6.031553398058253 21.37378640776699 -0.0404937099303892 0.6243416657063244 3.6299020440075784 3.196796368607097 0.791206465926963 0.2990226545155623 1.0 1.0 1.0 0.8920413772140755 0.2732224415470548 +Deoxyribonucleoside triphosphate metabolic process 0 7 2.3117801999384984 0.0207897990970522 2.3106796116504853 8.283980582524272 0.37885565145774 0.3611791401950917 1.8009119923381658 1.1145270578724225 1.2279981659947377 0.2841942772074602 0.0012750098077396 0.0595353304203936 0.1180585699575878 0.2740704871267072 0.4772731985221821 +Cytosolic transport 23 69 2.30619737660641 0.0210996061088803 15.3252427184466 64.33980582524272 0.1744021984538085 0.6762754968826091 7.447619264441359 7.422157064915613 0.8339042857759891 0.3289347094763193 1.0 0.5237470911105582 0.4440550029604954 0.1800030121383224 0.0405797644707419 +Regulation of inflammatory response to antigenic stimulus 2 8 2.3055811331177765 0.0211340485048667 2.237864077669903 7.104368932038835 -0.0715650533197143 0.5052554908619082 1.7699551036407 1.438472875449417 0.971684393530075 0.29962933075631 1.0 0.0039064712270754 0.0155240337321844 0.0840389641709933 0.0705348016344186 +Regulation of protein deubiquitination 4 9 2.2897829531428733 0.0220339018351016 2.354368932038835 6.885922330097087 -0.3490764455082842 0.4653114679612662 1.55190310346037 1.2634118830375136 0.9552587597826688 0.2862642073726715 1.0 0.0550816697898294 0.1094892401774078 0.0331187861076589 0.0181181417645757 +Serine family amino acid biosynthetic process 0 7 2.28050127284141 0.0225779753851473 2.4563106796116503 7.567961165048544 0.0499357125986692 0.4739437141304373 1.892892680421868 0.8259990822808096 1.0352035804275654 0.2949572954969333 1.0 0.0595353304203936 0.1180585699575878 0.2740704871267072 0.4772731985221821 +Regeneration 10 35 2.2764194758157994 0.0228209151026017 6.191747572815534 31.563106796116504 0.5380382799076718 0.5740012495882397 3.277553825936591 3.489707203654107 0.7812061797301654 0.3285807753592402 1.0 0.087320023469893 0.0801526286479979 0.4723805741734629 0.0129452724374584 +Protein autophosphorylation 22 40 2.273122912492976 0.0230187740385792 11.730582524271844 35.366504854368934 -0.345767035777637 0.6152861121415772 5.7915016959054055 6.2728529315186305 0.7494478075632884 0.3057449464100975 1.0 1.0 1.0 0.7662416228718193 0.6919639326303744 +Production of molecular mediator involved in inflammatory response 5 13 2.273008131562567 0.023025689921055 2.966019417475728 12.354368932038836 0.1592972255887565 0.61319676623286 2.187522134059814 1.790117244032998 0.8048602914317851 0.3023896321949654 1.0 0.1564797373419447 0.004885623522166 0.0563589352178582 0.0072126726017668 +Trna methylation 5 14 2.2568222173215364 0.0240191858910256 4.684466019417476 13.0 -0.1667695682670125 0.6113608461571705 2.924196256066093 3.1127673199822556 0.7950142109767884 0.2904828311985307 1.0 1.0 0.3209553841799009 0.2541035375726295 0.0120719478590556 +Cytokine production involved in inflammatory response 3 6 2.2516443209103225 0.0243447578618258 1.6844660194174756 6.915048543689321 0.5526695518877155 0.4572127495678942 1.5208746385948606 1.410799796429201 0.9262620288568464 0.3010153054171438 1.0 0.1029565435856987 0.0202898922491691 0.1067922158236129 0.0234644839392777 +Negative regulation of inflammatory response to antigenic stimulus 2 6 2.2502173376771037 0.0244351522385422 1.4635922330097086 5.060679611650485 0.3778208142338718 0.5031031490493427 1.507629370622294 1.4068858139407798 0.9208022859904784 0.3032829106068845 1.0 0.0021914548918381 0.0088504827764808 0.050241067872642 0.0336357980244025 +Neuron death 21 77 2.2451367492094625 0.0247593550669495 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 1.0 0.085412898243946 0.3573820216030455 0.1708365821366361 0.1205120626428805 +Regulation of alpha beta t cell differentiation 4 6 2.225676409585511 0.0260358640021383 2.2742718446601944 7.101941747572815 0.0138698526108014 0.4826884102779213 1.7994115013923857 1.076805828700402 1.001566756006478 0.2889592384465417 1.0 0.1197698958477507 0.2297987482657219 0.1392702662277763 0.0399552443236748 +Mismatch repair 5 12 2.222508762754184 0.0262489425033574 3.6529126213592233 11.45873786407767 0.0828860718784932 0.4809581195583483 2.894322574821655 1.7364583863143002 1.0614594046311725 0.3054071718849208 1.0 0.1114021565620111 0.0237627189197599 0.1227655047468798 0.031065887399213 +Regulation of cholesterol metabolic process 1 9 2.221797973309668 0.0262969617633728 2.2936893203883497 7.036407766990291 0.4249970400619817 0.3648416816190511 1.505220359503101 1.431658251221006 1.1754439785533268 0.2764552996129673 1.0 0.0056070915236824 0.0219975904219434 0.1147066696002357 0.3271248077551284 +Negative regulation of cation channel activity 3 8 2.2206923945577866 0.0263718029231716 2.133495145631068 6.012135922330097 0.3843341472061108 0.4773896383730598 1.4478455428656238 1.1179681209181225 0.991066221927023 0.3079680390661607 1.0 1.0 1.0 0.0088528623379573 0.0098193480789534 +Response to heat 19 43 2.2200998022314176 0.0264119936371727 9.308252427184469 36.31310679611651 0.0210888904704707 0.7302355793773286 6.400062943741517 4.228489029669047 0.6343994197175411 0.2764736963799276 1.0 1.0 1.0 0.5409227541708477 0.1502506041606015 +Pyridine nucleotide metabolic process 2 5 2.219375661380264 0.0264611780545529 1.0946601941747574 4.189320388349515 0.200529329767022 0.4956911637328702 0.9745651911065092 0.8993430851070943 0.9710489619646524 0.2859750902335083 1.0 0.0639684350193291 0.0077184558590264 0.0042425564235442 0.0278921605814954 +Ether metabolic process 0 9 2.2170701786481763 0.0266182962588894 2.3009708737864076 8.116504854368932 0.6936598083237113 0.3993528168351505 1.8983127483146185 1.066260782267489 0.9725930071190376 0.2989456029254039 1.0 0.0814971443263516 0.1596960736798767 0.3582816735878424 0.5927878722461318 +Regulation of cell adhesion mediated by integrin 3 6 2.216207534942654 0.0266772920797246 1.5315533980582523 5.002427184466019 0.0190009315921689 0.4788044844341372 1.324333323602112 1.724324528518154 1.057883560787105 0.3020231241870391 1.0 1.0 1.0 0.4860897569734319 0.14168603717257 +Wound healing 13 63 2.212582687528638 0.0269264296920763 11.9126213592233 59.99029126213592 0.1446120400866948 0.6484734112111603 6.210086996743008 7.840330320006731 0.7798797329713693 0.3108096826634549 1.0 0.0964040929059835 0.0246145445697769 0.0115483850865517 0.1635785283526323 +Negative regulation of response to external stimulus 17 55 2.2032139123869885 0.0275796751898513 9.381067961165048 47.019417475728154 0.8063071074275461 0.4700507256615295 4.127569023520378 6.3589713134688575 0.9364755672970396 0.3491987458588393 1.0 0.0083723537592248 0.0243497840139476 0.023795781556892 0.0735353281593083 +Pyrimidine containing compound catabolic process 0 7 2.195490181174933 0.0281284544674524 2.179611650485437 7.150485436893204 -0.0583277904817654 0.420942781869248 1.964928379993796 1.313364743251867 1.1511745440559666 0.2917499803945465 0.0028442526480391 0.1280604643503683 0.2445730022705269 0.1562190614045352 0.4155646604676148 +Deoxyribose phosphate catabolic process 5 6 2.194612248189122 0.0281914241963487 1.7572815533980584 7.25 0.4417369759637933 0.3797188803533401 1.5809301638161015 1.1979452473022214 1.1866734243944994 0.2993182794477304 0.0021577089054228 0.0987043131013681 0.191600110602388 0.0990342687178565 0.2906426697670494 +Regulation of protein catabolic process 51 140 2.192176539753034 0.028366761757657 30.24514563106796 123.29854368932038 -0.0250839491420676 0.7567476349416642 13.393615372474375 11.603928771226704 0.7450756992782206 0.300701858967686 1.0 0.7669096772504154 0.168213828396044 0.0677423707191439 0.0131926550608322 +Escrt complex disassembly 4 7 2.1887942932087854 0.0286117947106765 2.95873786407767 6.334951456310679 -0.1803367519990314 0.5335470166401733 1.8409438164072944 1.573272437530148 0.9378304399004606 0.3132763636446821 1.0 1.0 0.0921025797166938 0.0015031185668187 0.000918782674844 +One carbon metabolic process 2 13 2.184319310140179 0.0289387927993671 3.6310679611650487 12.451456310679612 0.0728624298251617 0.5704222327170899 2.7973298338352546 0.859031298826235 0.8584197811869867 0.2930893531997819 1.0 0.1071891284628969 0.0219975904219434 0.0197332243190265 0.1088149775417643 +Protein transport along microtubule 2 5 2.1717409686764007 0.0298752064990153 1.5946601941747574 4.288834951456311 -0.0111075410171745 0.4975104992993215 1.1837371424417156 1.2094175770475637 1.0712803318081294 0.3237118734410871 1.0 1.0 0.0921025797166938 0.0233125205204954 0.0106255777102749 +Pyrimidine deoxyribonucleotide metabolic process 1 6 2.1705832721760903 0.0299626876989518 2.0388349514563107 6.660194174757281 0.1294505442217243 0.4040744110153614 1.7090412352055069 1.2963982821592612 1.1908221881064291 0.2943892670721009 0.0016673205178158 0.0771453392642774 0.1515272625734178 0.0630532374058985 0.1992011927715255 +Protein deneddylation 4 8 2.16710908186741 0.0302265375951567 3.4393203883495147 8.390776699029127 0.4583886519170358 0.5047381765460944 2.0653656965433753 0.9374683832290835 0.8789112479982977 0.3140785399167275 1.0 1.0 0.0921025797166938 0.2183511668733661 0.000918782674844 +Jnk cascade 10 21 2.161890631825899 0.0306266072717495 5.116504854368932 17.9126213592233 -0.0898543541406848 0.6099132434800317 2.809660764078065 3.5930266769523653 0.800154357937779 0.2904722463869471 1.0 1.0 0.6391647109532668 0.4723805741734629 0.249621290178596 +Response to transforming growth factor beta 8 38 2.160244039111735 0.0307537825727899 8.410194174757281 32.536407766990294 -0.094101059672419 0.6394779055878194 4.225924723432897 4.710671082480533 0.7756039910569711 0.2958728495226654 1.0 0.5122009359255594 0.4276292777269929 0.1622796088302703 0.31394996595046 +Glutathione metabolic process 4 20 2.1551214585207727 0.0311523309283132 5.737864077669903 19.91504854368932 -0.2315144781601271 0.5572250910251842 3.0583680052131608 1.719411376919556 0.902925048098778 0.3068938618813106 1.0 0.1564797373419447 0.2941077913158182 0.0109251570181746 0.0072126726017668 +Nucleoside monophosphate metabolic process 21 39 2.146664853604203 0.0318199727472015 13.359223300970871 36.11893203883495 -0.4651610104204346 0.5239550170823286 6.753071029448561 3.4979787263702105 1.1096524861981665 0.3525375915116363 1.0 1.0 0.1290920553826253 0.2100263434971256 0.0953101243725822 +Pteridine containing compound metabolic process 2 19 2.1400440637134097 0.032351205898472 3.83495145631068 17.62864077669903 0.7459938330774762 0.4836011399422016 2.590487030636505 1.3813793223165276 0.7670194449127248 0.3150925598502537 1.0 0.1321770275159086 0.2518545844225215 0.0356014336373073 0.1773693871336699 +Pteridine containing compound biosynthetic process 1 9 2.136919269332586 0.0326045584350205 2.6067961165048543 8.104368932038835 0.160338473204254 0.4909996134440021 2.2749698444996973 0.914436714412676 1.0072278525407212 0.3042349018536225 1.0 0.0595353304203936 0.1180585699575878 0.0385233102424958 0.129364196063302 +Positive regulation of protein polymerization 14 31 2.133541955435498 0.0328802937556582 8.29126213592233 29.067961165048544 -0.1407148677954534 0.5820281683314947 5.027364087585942 2.9976111392542504 0.9226797177142148 0.3196707976657912 1.0 1.0 0.4925597827158772 0.5109892685584014 0.0529729865665092 +Pyridine containing compound biosynthetic process 1 5 2.1304602310105323 0.0331336357461675 1.1771844660194175 4.592233009708738 0.442191494479448 0.5006889660618573 1.0613070504301176 1.0375184471761203 0.8939647210170195 0.2921877271034155 1.0 0.0683810764565047 0.0088504827764808 0.050241067872642 0.16360549489043 +Regulation of response to reactive oxygen species 0 7 2.1221988645487757 0.0338210418693454 2.179611650485437 7.944174757281553 -0.0623480553155879 0.4810439073108864 1.7381420290822969 1.2692364681879964 0.9814591255351324 0.2740586473575921 1.0 0.1071891284628969 0.2070995190727305 0.4465871194719102 0.6982802819387028 +Folic acid containing compound metabolic process 1 15 2.10684039623371 0.0351314165775324 2.878640776699029 14.104368932038836 0.8133801810126406 0.4364886260763115 1.836742075927617 1.0269572077782 0.765409664716209 0.2922054181085946 1.0 0.1071891284628969 0.2070995190727305 0.1147066696002357 0.3271248077551284 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 5 15 2.097827056859084 0.035920425465967 4.094660194174757 11.37864077669903 0.002182340961636 0.524688059582186 2.6764471869861683 2.8680242678638037 1.0149817540499388 0.3268991027874168 1.0 1.0 0.0398064357050217 0.0453869127531283 0.0205229364106292 +Organic cation transport 0 6 2.091472770253281 0.0364857048740359 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 1.0 0.0944323477659319 0.1837383274168749 0.4040612158985918 0.649472544545447 +Regulation of transporter activity 19 49 2.0899681385813613 0.0366206618953421 10.191747572815531 43.932038834951456 0.1012053456490613 0.6855065791009368 4.523898766858667 5.186356515069559 0.7027420284840898 0.3005709748881068 1.0 0.4683204087456599 0.0390712286884639 0.0158285055444122 0.0591404584850555 +Protein k48 linked ubiquitination 7 14 2.0875698914966576 0.0368366503212085 4.055825242718447 11.155339805825244 -0.0465840331509609 0.5637128886680042 2.4779199796947786 1.964526581738523 0.9309477767022024 0.3089866453102476 1.0 1.0 0.4297892617739207 0.4139938852214621 0.3116472395700642 +Axonal transport 13 25 2.0866930257928944 0.0369158921056707 5.868932038834951 20.771844660194176 -0.2839082282867138 0.5740097441434391 3.2007744550164943 2.933963073331934 0.8776354781942454 0.3217070379297994 1.0 1.0 0.4186050092003007 0.3968935357399609 0.0535493385180635 +Syncytium formation 1 9 2.084818076822983 0.0370858172054089 2.157766990291262 7.036407766990291 0.4033414225617926 0.536077368027232 1.4867906611148458 1.1453302015660312 0.8381553292924435 0.3029132102629827 1.0 0.1155957163384056 0.0255840399150975 0.1309570889500886 0.3630866560691931 +Anterograde axonal transport 9 18 2.0799462028918865 0.0375304675325141 4.347087378640777 14.138349514563108 -0.1703437985376459 0.5780296844537811 2.663747317044918 2.551942948006167 0.8906951515212843 0.3137187606930002 1.0 1.0 0.3404254693467198 0.2813288077075832 0.0169717228577044 +Modification of postsynaptic actin cytoskeleton 2 5 2.073081620037688 0.0381646842298997 1.2718446601941749 4.691747572815534 0.7749873285721138 0.3698922532933065 1.1736936531325053 0.5210425083463128 1.0158209432526408 0.3028676273114866 1.0 1.0 0.0743799864466655 0.014977467250991 0.0053334351931861 +Endosomal transport 23 81 2.073019417437093 0.0381704725159588 18.62621359223301 73.93932038834951 0.1186519085167339 0.644720288610979 8.11663114827185 10.15480695988343 0.8992829354823526 0.3430729564402452 1.0 0.618158879829211 0.3072324825572405 0.1197478521495697 0.0374002200167604 +Negative regulation of proteolysis involved in cellular protein catabolic process 15 28 2.0631240919365883 0.0391008397452541 7.422330097087379 26.51941747572815 -0.0625403006026407 0.6537376621895988 4.044207941194226 2.5028356055547203 0.7842854494400002 0.2946217252178134 1.0 0.225458320485449 0.4072036678679048 0.1435696883620607 0.1208874805839759 +Tissue regeneration 2 5 2.062041672436592 0.0392037686830168 2.237864077669903 5.939320388349515 0.0058255705017962 0.5074833040137664 1.523831177412142 1.1756871670759337 0.9998757083281912 0.3118745730683118 1.0 0.1564797373419447 0.2941077913158182 0.5885248237912099 0.2544916035409682 +Regulation of muscle cell differentiation 3 23 2.0573477869658614 0.0396527837352802 5.728155339805825 20.618932038834952 -0.0781689915050914 0.6600776989817899 3.377378125853805 3.3937307742655154 0.7050779843083667 0.2777937294827721 1.0 0.0461595615554375 0.0052630916622981 0.1017129224833184 0.2817090990841858 +Negative regulation of muscle cell differentiation 1 11 2.0532602078139384 0.0400473479139329 3.162621359223301 9.567961165048544 -0.1093054930835953 0.6155971043836854 2.343191111451753 1.380425823723436 0.748791053373036 0.2834727604867062 1.0 0.1524760813950871 0.0443091130960601 0.2089591760219589 0.5133655979735248 +Neuron apoptotic process 10 54 2.050837217538512 0.0402828018233498 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 1.0 0.1536302836663208 0.4176554250980517 0.2919675535026375 0.1063137228069698 +Folic acid containing compound biosynthetic process 0 6 2.048133336415628 0.0405469362445467 2.0364077669902914 5.548543689320389 0.1185786473734218 0.460967837187085 1.9007241105446349 0.5306826667147115 1.0747056928647158 0.3004314837246528 1.0 0.0370595951599339 0.0743799864466655 0.1788587842302525 0.3290745839784397 +Rna stabilization 5 29 2.043275432273603 0.0410251801871051 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 1.0 0.0221752921749746 0.0115248505447769 0.0011347755104788 0.0305407497227627 +Negative regulation of sodium ion transport 3 5 2.041367501402528 0.0412143122017916 1.2773722627737227 3.4525547445255476 0.2823941870087115 0.4625043271816547 1.1252245648200372 1.426056459468504 1.1882397717936877 0.3126093480538577 1.0 1.0 0.0077184558590264 0.0442367692127036 0.0037486095651754 +Positive regulation of endothelial cell proliferation 1 15 2.0413162510316343 0.0412194027889278 2.5776699029126213 10.847087378640778 0.5110353339210854 0.5145159989917648 2.19139677223592 1.976418321285878 0.797076934554805 0.2911296630341599 1.0 0.1916891885455893 0.3530974878629287 0.6706077438596076 0.6506586407039905 +Dendritic spine development 15 25 2.037871082525488 0.0415628272379406 7.543689320388349 23.533980582524272 -0.0662850934161216 0.5788040721884481 4.8861339354869315 2.485161923503321 0.8816903143735362 0.3057996790234123 1.0 1.0 0.1588529428511447 0.5409227541708477 0.7052990840242708 +Tetrahydrofolate metabolic process 0 10 2.0359818692624527 0.0417521759097812 2.883495145631068 10.37621359223301 0.1236311528006924 0.5333218465215749 2.2835459178029023 0.7547372930780776 0.9208718803519323 0.2982675337711581 1.0 0.0727733471903131 0.1432798584585485 0.3258327648280404 0.5500037614421638 +Positive regulation of cytoskeleton organization 22 50 2.032518771943532 0.0421011653549205 13.235436893203884 47.70873786407767 -0.205437944853101 0.6155485550669894 6.976757985883583 5.653216402064078 0.8612276872814943 0.3258637695512297 1.0 1.0 0.738650813732564 0.656896860216663 0.0729574196702931 +Translational initiation 38 70 2.026866276039942 0.0426760902465102 20.473300970873787 66.03155339805825 -0.3299051180773463 0.5812942370765041 8.907385709149034 3.2525530695823575 0.9405599960406624 0.3351549568938746 1.0 1.0 0.628446438408612 0.2363926835560278 0.0105367578989368 +Inflammatory response to antigenic stimulus 3 11 2.018014023981084 0.0435898007931103 3.0825242718446604 9.844660194174756 -0.0445797977919255 0.5149388776250523 2.1481501269365415 1.888942178690209 0.947675222647861 0.2939980457802699 1.0 0.0081256981844374 0.031373049189738 0.1562190614045352 0.0501437556032915 +Negative regulation of jnk cascade 4 6 2.013692244248635 0.0440418548076846 2.3689320388349513 5.162621359223301 -0.2703395817123714 0.5177420562894756 1.332858023175907 0.9005181476800259 0.8866073512073387 0.2936514575850711 1.0 1.0 0.2070995190727305 0.1147066696002357 0.1088149775417643 +Phospholipid dephosphorylation 2 7 2.011317338013922 0.0442919483038413 1.5097087378640777 5.133495145631068 0.2642559626879384 0.5011003069511705 1.1373632053119338 1.5592332001039908 1.0020710614418686 0.3103616798127063 1.0 0.1444128696349771 0.2732850813359189 0.1911341037783432 0.2151867556135544 +Regulation of axonogenesis 12 28 2.010986255817269 0.044326908478927 6.298543689320389 24.33009708737864 -0.0369493998932667 0.7042332477256763 3.680926674103965 3.330903692400873 0.6576030741176464 0.2748175369765668 1.0 1.0 1.0 0.1953902083202122 0.0388539220133518 +Trna modification 12 35 2.007940532015104 0.0446496113866381 10.347087378640778 28.097087378640776 -0.444652565026619 0.5477750580830718 5.264685080075063 6.581106471591478 0.9493994221018446 0.3229789458528009 1.0 1.0 0.5614825641059915 0.0045575961472511 0.0007906234883712 +Cellular aldehyde metabolic process 3 22 2.007908475460007 0.0446530183791158 7.91747572815534 20.08252427184466 -0.7938265262942007 0.3375522872688842 4.247556171950748 1.3156951859098711 1.215650778116283 0.3011725166646586 1.0 0.0136970422924113 0.0513963234576887 0.013184387389335 0.1114244714574529 +Nucleoside monophosphate biosynthetic process 18 26 2.0073719281806417 0.0447100755508182 10.519417475728156 24.43446601941747 -0.46572953328444 0.4668532857531798 5.829046088464405 2.1940069422035915 1.2456954597659804 0.347724228093804 1.0 1.0 0.327507803675052 0.6363606533565179 0.3217125501336962 +Cytoplasmic sequestering of protein 6 10 1.9943150946274917 0.0461176306726605 3.91504854368932 10.033980582524272 -0.4532978900101785 0.5234169906669717 2.219740811330947 1.0491840008235571 0.8381515062769284 0.3093834295815014 1.0 1.0 0.1837383274168749 0.4040612158985918 0.2722934148112151 +Regulation of syncytium formation by plasma membrane fusion 1 6 1.9916031692377305 0.046414615379339 1.5145631067961165 4.881067961165049 0.4788760389365136 0.4988531191063783 1.1688852682318214 1.060285190268009 0.8935284827681266 0.3080127656634198 1.0 0.0506073598520519 0.0047533286028597 0.0280420066437826 0.0971506673250001 +Positive regulation of syncytium formation by plasma membrane fusion 1 6 1.9916031692377305 0.046414615379339 1.5145631067961165 4.881067961165049 0.4788760389365136 0.4988531191063783 1.1688852682318214 1.060285190268009 0.8935284827681266 0.3080127656634198 1.0 0.0461123069087121 0.0039135152062846 0.0233125205204954 0.0820486275159116 +Glycine metabolic process 0 8 1.988643562144509 0.0467405595210617 1.9611650485436891 7.745145631067961 0.2494288083790708 0.5022368368742125 1.850858263769758 0.52194625337572 0.9488090090216508 0.2970164640348599 1.0 0.04159641685533 0.0832836732680532 0.1988473022417859 0.0677640175569944 +Regulation of inflammatory response 9 38 1.9842117888065929 0.0472322348942633 7.866504854368932 35.21844660194175 0.2295827008417531 0.6281567589262068 3.713547020474819 5.919020641452837 0.77351812014651 0.3063504476591706 1.0 0.0333414242092628 0.0562914471207365 0.0733930651311545 0.1946915422899277 +Regulation of response to oxidative stress 2 22 1.982963668472835 0.0473714879279949 5.211165048543689 20.733009708737864 -0.1485738525286393 0.5996084619237002 2.7898170594478344 2.3163785071216783 0.7948536019536501 0.2853863894833109 1.0 0.0333019544595367 0.0207328276809773 0.1850558266034752 0.5755862499585266 +Protein export from nucleus 15 28 1.9803408503675632 0.0476652415157672 8.509708737864077 26.40776699029126 -0.411416923490922 0.5869509659884903 3.8361341423215136 2.1471900499851007 0.790978746232196 0.3224531672526008 1.0 1.0 0.08610744549237 0.0014035458573663 0.0029760556157756 +Cellular response to vascular endothelial growth factor stimulus 2 8 1.9789080728708373 0.0478263571830437 2.2354368932038833 6.213592233009709 -0.2739927244592021 0.4779011439627239 1.510611833031637 1.687478071411025 1.0023419766853818 0.297801109567981 1.0 0.0110614955842043 0.0041517217414646 0.0489147892655661 0.228153712059568 +Positive regulation of alpha beta t cell differentiation 3 5 1.9763464618369544 0.0481155507623924 2.0266990291262137 6.046116504854369 -0.0196580109508001 0.4750955445743636 1.6813557222540203 1.0359131172191125 1.0124328221039909 0.2975873822729644 1.0 0.0901405579438761 0.1758008751515455 0.0840389641709933 0.0705348016344186 +Vesicle transport along microtubule 8 13 1.9628334740468916 0.0496655268667358 4.514563106796117 11.58980582524272 -0.102125747194735 0.5711972684164484 2.4921783572738394 1.5404554115317726 0.8762002857901487 0.2964402233799867 1.0 1.0 1.0 0.2450354162713742 0.1196653936274396 +N terminal protein amino acid modification 4 9 1.960914852835347 0.0498889563952786 2.45873786407767 8.439320388349515 0.5804938412353885 0.4249038973587519 1.7696871423418874 1.4824892226959214 1.0345977331938565 0.310740936912418 1.0 1.0 0.2223047329091382 0.0244664942800011 0.0353483729682259 +Positive regulation of cation channel activity 5 8 1.9607763906378997 0.0499051133116978 2.4684466019417477 7.276699029126213 0.0438926340617352 0.528833901866312 1.6769350551489708 1.3710391412692278 0.9471475366324456 0.3019789925380542 1.0 1.0 1.0 0.0326106125072858 0.0501437556032915 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cb981b380195811dc01479b52593fa45315574cd --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 6592, + "title": "Average number of proteins per term", + "value": 20.43795509708738 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d417bc306e859af8f8f646f25d4caa7eab106cd0 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..52d5e00ea880ede9687b7bd9d4f275d477f70fcd --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2318 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Dephosphorylation 0.4613724622761296 3.3606415651125765 0.0007776166883519 0.9940718512240408 0.1278402325874774 100 Q8IV63,P17931,P62942,P34913,P30153,Q99504,O43768,A6NDG6,Q9NPH0,O15355,Q969T7,Q5H9R7,Q06124,Q13526,P53041,O95429,P31946,Q9P2B4,Q9H0R4,P30154,Q8TF05,Q9NY27,Q14738,Q96P16,Q9BRF8,Q15435,Q5TFE4,P78318,P42858,Q9UNI6,P08238,Q9H2U2,P49841,Q9NQG5,Q9UHD1,Q01968,Q8NCE2,O60942,Q13614,Q15257,P63151,P51452,P0DP25,Q9NQ88 44 +Cytoplasmic translation 0.4241325923133351 3.2566116646047125 0.0011275057215649 0.9994107800249262 0.1278402325874774 116 P46778,P46783,P42345,P05386,P20042,P62917,P27635,P18621,P55039,P46781,P62701,P15880,P62269,P46776,P62280,P46777,P67809,P61247,P61513,P23588,Q8WU90,P62841,P62847,Q9NR50,Q14240,Q15056,Q9ULC4,Q9BQC3,P14618,P23396,P62241,Q14152,P84098,P62899,P08865,P16989,P62906,P39019,P39023,P83731,P15170,Q04637,Q9BTV6,P83881,P62750,P47914,P60842,P62495,O15371,Q9Y5A9,P62081,P05387,P32969,Q86U44,P62753,P62277,P62266,P05388,P55010,P08708,P26373 61 +Secondary alcohol metabolic process 0.5335125729478858 3.2364852390349124 0.0012101148482595 0.999658412799766 0.1278402325874774 46 P48735,P34913,O75874,Q16850,Q15125,Q9UBM7 6 +Proteasomal protein catabolic process 0.3748830197118943 2.970707244979006 0.0029711486072925 0.9999999969707948 0.1278402325874774 172 Q93034,Q99497,O95155,P51665,Q92995,Q8WW12,P49721,Q6NTF9,Q9UNN5,P28070,Q9H1I8,Q13200,P28074,P24941,Q15008,Q96J02,Q99460,Q15370,P48556,Q9GZU8,P48729,P20618,P62333,Q16763,Q8N3C0,P63208,P60900,Q9NXV2,P17612,Q96KB5,P17980,P78559,Q96PU5,P25788,P08238,P25789,Q99436,P25787,P49841,O75832,P61289,Q9GZP4,Q9NZJ0,Q7Z6Z7,Q9UL46,P46934,P28066,P49427,O94888,P54727,P28072,P10398,Q13309,P54725,O95260,O94966,O14965,P49720,Q9UBU6,P25786,Q04323,Q8IYU2 62 +Pyrimidine nucleotide metabolic process 0.6915047514419209 2.900087452214514 0.0037305856084945 0.9999999999800544 0.1322151630709483 18 Q9H773,P15531,P33316,P23919,P13051,P22392,Q9NRF8,P17812,P60891 9 +Response to wounding 0.4367154279019025 2.8682231431342835 0.0041278428970765 0.9999999999985608 0.1409483129242395 84 P00374,Q9C0E8,P46108,Q16512,Q16539,Q6SZW1,Q96AY3,Q02750,Q9NZZ3,P04083,Q96AC1,Q96G23,P42785,P04792,O00203,Q99439,Q9HD42,P46821,P07196,O75122 20 +Nadp metabolic process 0.6933587219047616 2.8267797241505077 0.0047018658720368 0.9999999999999678 0.1451539058225815 16 P48735,O75874,Q9BQG2 3 +Modified amino acid transport 0.8973260965569781 2.819034390650347 0.0048168357026008 0.999999999999985 0.1470026895904846 7 O43772 1 +Protein dephosphorylation 0.434370660798912 2.8078149747985486 0.0049878875665501 0.9999999999999952 0.1494552492668105 78 Q8IV63,P17931,P62942,Q99504,P30153,O43768,A6NDG6,O15355,Q5H9R7,Q06124,Q13526,P53041,P31946,Q9P2B4,P30154,Q8TF05,Q9NY27,Q14738,Q96P16,Q9BRF8,Q15435,P42858,Q9UNI6,P08238,Q9H2U2,P49841,Q9NQG5,Q8NCE2,O60942,Q13614,Q15257,P63151,P51452,P0DP25 34 +Cellular carbohydrate metabolic process 0.439533926918045 2.7862624879856406 0.0053319676251617 0.9999999999999996 0.151146019691695 65 Q9BYT8,P48735,P85037,Q9UNI6,O43505,P06737,O75874,Q13572,P49841,Q13614,P13807,O14874,Q9UJ70,Q9Y223,Q01968,Q9NQ88,P46976,P17174 18 +Cellular response to reactive oxygen species 0.5656302904391984 2.7766979883118106 0.0054914178398175 0.9999999999999998 0.151146019691695 29 P00374,Q99720 2 +Stress activated protein kinase signaling cascade 0.4914302935280832 2.7554576150090795 0.0058610097748919 1.0 0.151146019691695 43 P09429,Q16539,Q02750,Q13546,P46109,P98170,P36507,O95251,P15311,P31689,Q53EL6,P43034,Q96J02,P51452,Q96KB5,Q92905,P78318 17 +Negative regulation of transporter activity 0.6648528959158647 2.7456332942180386 0.0060394227959195 1.0 0.151146019691695 18 Q9P2B4,P62942,P46934,P28161,Q12955,P0DP25,Q96PU5 7 +Dicarboxylic acid metabolic process 0.4779448959658563 2.7032121894743337 0.0068672891659267 1.0 0.1593114792587934 45 P48735,P00374 2 +Negative regulation of stress activated protein kinase signaling cascade 0.7527113539363949 2.6557364006212807 0.0079135445472209 1.0 0.1754987444815784 11 P43034,P31689,Q53EL6,P51452,Q96J02,Q96KB5,P78318 7 +Tricarboxylic acid metabolic process 0.7669807340408913 2.652623231086845 0.0079868967452174 1.0 0.1754987444815784 10 P48735 1 +Negative regulation of ion transmembrane transporter activity 0.6599294657981527 2.6369966804684437 0.0083643650108369 1.0 0.1775642583675523 16 P62942,P46934,P28161,Q12955,P0DP25,Q96PU5 6 +Pyrimidine nucleoside triphosphate metabolic process 0.731269541512515 2.623272279029514 0.0087089642283029 1.0 0.1775642583675523 12 Q9H773,P15531,P33316,P22392,Q9NRF8,P17812 6 +Response to axon injury 0.6486896352703226 2.6100938156683604 0.009051739512746 1.0 0.1775642583675523 17 Q6SZW1,P46821,P00374,Q96G23,P07196 5 +Regulation of response to external stimulus 0.3341454957844703 2.596168090570774 0.0094269934923982 1.0 0.1822367774248958 141 Q99497,P98170,P28070,Q06124,Q9UMX5,Q96J02,P46108,Q16512,P80303,P30046,P09429,Q16539,P19474,Q02750,Q9BVA1,Q9H4A3,P04083,Q9Y3Z3,Q16543,Q9NUD5,P60900,Q53EL6,Q96G23,Q9UNH7,P14174,Q96KB5,P08238,P39019,Q13177,P04792,Q9HCK8,Q9NUQ9,Q13546,Q8TDB6,Q92879,Q9Y5A9,Q9BXW9,Q7Z739,P51452,O75122,O95747,Q7Z460,P25786 43 +Nucleoside phosphate catabolic process 0.6389466941144221 2.5927401357956468 0.0095214684185527 1.0 0.1827926899502903 18 O43598,Q6SZW1,Q9H773,P00491,Q9Y3Z3,Q9BQG2,Q9UKK9,P13051 8 +Pyridine containing compound metabolic process 0.7625015008519022 2.5605185517484057 0.0104516083091128 1.0 0.1925772239048119 9 P43490,Q13126,Q9BQG2 3 +Response to reactive oxygen species 0.488521083009532 2.5556360608859814 0.0105993913402879 1.0 0.1935489964409373 37 P00374,Q99720,P04083,P46108,P23396 5 +Neuron projection regeneration 0.7292786428018166 2.5385211154755947 0.0111322084950944 1.0 0.1966498308920752 11 P46821,P00374,Q96G23,P07196 4 +Regulation of stress activated protein kinase signaling cascade 0.4982712871521879 2.524233698167037 0.0115950817991137 1.0 0.199192459908644 32 P09429,Q02750,Q13546,P98170,P36507,P43034,P31689,Q53EL6,P51452,Q96J02,Q96KB5,Q92905,P78318 13 +Deoxyribose phosphate metabolic process 0.7117963188975418 2.5234280457407263 0.0116216841628498 1.0 0.199192459908644 12 Q9H773,P00491,Q96G03,P33316,Q9Y3Z3,P23919,P13051 7 +Regulation of jnk cascade 0.6536110343588657 2.4954678476891927 0.0125791154632541 1.0 0.2099515216963561 15 P09429,P98170,P31689,Q53EL6,P51452,Q96J02,Q92905,Q13546 8 +Isocitrate metabolic process 0.8675310394489519 2.4705170500835805 0.0134917887221743 1.0 0.2168411606418919 6 P48735 1 +Microtubule anchoring 0.7009986183573867 2.4675530107203794 0.0136040076626682 1.0 0.2168411606418919 12 P49841,Q8IWJ2,Q9P287,Q86VS8,Q14203,O75122,Q8TD16,Q7Z460 8 +Alcohol metabolic process 0.3986404946259186 2.4599272532203167 0.0138965180428496 1.0 0.2168411606418919 90 P48735,P00374,P34913,O75874,Q16850,Q15392,Q15125,Q9UBM7 8 +2 oxoglutarate metabolic process 0.7384022003161329 2.4435935669781 0.0145417982752822 1.0 0.2191418045107392 9 P48735,O75874 2 +Retrograde transport endosome to golgi 0.4828714785006214 2.4388340228652323 0.014734734192831 1.0 0.2207531086344135 34 Q9UJY5,Q8IWJ2,O75436,Q9C0C9,Q9UID3,O15260,O60271,Q4J6C6,Q14203,Q9UNH7,Q13596,Q9Y5X3,O60749 13 +Benzene containing compound metabolic process 0.8087469829550904 2.431644013986502 0.0150304717454792 1.0 0.2228537529695127 7 P28161,P34913,P21266 3 +Alpha beta t cell differentiation 0.7319744168234953 2.412130163298866 0.0158596184386743 1.0 0.2282676959557669 9 P09429,P00491,P04083,O00203,O14617 5 +Folic acid metabolic process 0.7549277279465809 2.407707671398321 0.0160530292660534 1.0 0.2290801520984548 8 P00374 1 +Regulation of early endosome to late endosome transport 0.6861689500683634 2.3902153810787934 0.0168384947974384 1.0 0.2290801520984548 12 Q13614,Q02750,Q9UMY4,P26038,O75165,P36507,O60493,P15311,P35241 9 +Pyrimidine containing compound metabolic process 0.5334099907300822 2.3887930673063513 0.0169038204020872 1.0 0.2290801520984548 27 Q9H773,P15531,P11172,P33316,P04183,P22392,P23919,P13051,Q16555,Q9NRF8,P17812,P60891 12 +Regulation of mitochondrial fusion 0.7989384825832679 2.3876293883015336 0.0169574324758587 1.0 0.2290801520984548 7 Q8N2A8 1 +Regulation of cellular response to heat 0.7125378352564538 2.383500700616705 0.0171488518260372 1.0 0.2290801520984548 10 Q99543,P49841,Q99615,P25685,Q13535,Q9UHD1,O75190 7 +Negative regulation of lymphocyte activation 0.608082247190271 2.3692196160415895 0.0178256651668093 1.0 0.2322268473905286 17 O15347,P04083,P51452,Q96J02,Q16512 5 +Regulation of cytoplasmic transport 0.6415693912579404 2.3298990955341634 0.0198114848461004 1.0 0.248777942400146 14 Q13614,Q02750,Q9UMY4,P26038,O75165,P36507,O60493,P15311,P35241 9 +T cell receptor signaling pathway 0.588954167278586 2.328857716439213 0.0198666045985045 1.0 0.248777942400146 19 P49770,P46109,Q14232,O95999,Q9H4A3,Q9NR50,P15311,Q13144,P51452,P23396 10 +Antigen receptor mediated signaling pathway 0.5805755260327216 2.317541919528596 0.0204742298904263 1.0 0.248777942400146 20 P49770,P46109,Q14232,O95999,Q9H4A3,Q9NR50,P15311,Q13144,P51452,P23396 10 +Cytosolic transport 0.3910832039609624 2.30619737660641 0.0210996061088803 1.0 0.248777942400146 69 Q9UJY5,Q99570,P36507,O75436,O60493,Q9UID3,P15311,O15260,Q14203,Q15075,Q02750,Q86VS8,O60271,Q9UNH7,Q13596,Q8NEB9,Q8IWJ2,Q9C0C9,Q4J6C6,Q9Y5X3,Q13614,Q96RL7,O60749 23 +Regulation of inflammatory response to antigenic stimulus 0.7335655573136715 2.3055811331177765 0.0211340485048667 1.0 0.248777942400146 8 Q16539,P28070 2 +Regulation of protein deubiquitination 0.7072033234508367 2.2897829531428733 0.0220339018351016 1.0 0.2557173959454054 9 Q01804,Q04323,P19474,Q96J02 4 +Regeneration 0.4611156184327424 2.2764194758157994 0.0228209151026017 1.0 0.2611702960494786 35 P46821,P00374,Q02750,P52294,P62841,Q7Z4V5,P04083,Q96G23,P07196,P11908 10 +Protein autophosphorylation 0.4473431930879649 2.2731229124929757 0.0230187740385792 1.0 0.2611702960494786 40 P42345,P36507,P33981,Q13043,P51617,Q16512,Q13535,Q9P289,P17612,P19525,P49841,Q13177,Q13263,Q9UHD1,Q13546,Q99986,Q00535,P41240,Q96Q15,O14965,O95747,P0DP25 22 +Production of molecular mediator involved in inflammatory response 0.6478141131583336 2.273008131562567 0.023025689921055 1.0 0.2611702960494786 13 Q16539,Q96AQ6,Q53EL6,Q9UNH7,O60684 5 +Trna methylation 0.6285502380938668 2.2568222173215364 0.0240191858910256 1.0 0.2638907889894023 14 Q9UI30,Q9NXH9,Q9UBP6,Q9UJA5,Q969Y2 5 +Cytokine production involved in inflammatory response 0.8163029815670199 2.2516443209103225 0.0243447578618258 1.0 0.2646735375173745 6 Q16539,Q53EL6,O60684 3 +Negative regulation of inflammatory response to antigenic stimulus 0.8159731050926986 2.2502173376771033 0.0244351522385422 1.0 0.2646735375173745 6 Q16539,P28070 2 +Neuron death 0.3861227858097121 2.2451367492094625 0.0247593550669495 1.0 0.2671254805259112 77 Q99497,Q99720,P98170,Q9UMX5,Q96B36,Q6SZW1,Q01105,O43813,Q9UNH7,P06744,P08238,P31751,P49841,Q9UHD1,O95831,Q00535,P49427,Q15392,P07196,Q9NQ88,P51858 21 +Regulation of alpha beta t cell differentiation 0.8103080354245695 2.225676409585511 0.0260358640021383 1.0 0.2754596686634211 6 P09429,O00203,P04083,O14617 4 +Mismatch repair 0.6544563824716683 2.2225087627541837 0.0262489425033574 1.0 0.2754596686634211 12 P09429,P54277,P35244,Q9UQ84,P18858 5 +Regulation of cholesterol metabolic process 0.6935885154499928 2.2217979733096676 0.0262969617633728 1.0 0.2754596686634211 9 P34913 1 +Negative regulation of cation channel activity 0.7159985504061315 2.2206923945577866 0.0263718029231716 1.0 0.2754596686634211 8 P0DP25,P62942,P28161 3 +Response to heat 0.4325341577044908 2.2200998022314176 0.0264119936371727 1.0 0.2754596686634211 43 Q14232,Q99543,P42345,P25685,P51617,Q9NR50,Q13535,P31689,P17612,P08238,P49841,Q99615,O95817,Q9UHD1,P49770,Q9UER7,O60884,Q13144,O75190 19 +Pyridine nucleotide metabolic process 0.8660509077709643 2.2193756613802633 0.0264611780545529 1.0 0.2754596686634211 5 P43490,Q9BQG2 2 +Regulation of cell adhesion mediated by integrin 0.808126280742596 2.216207534942654 0.0266772920797246 1.0 0.2756374755322024 6 Q9H4A3,P46108,P46109 3 +Wound healing 0.3918428378211405 2.212582687528638 0.0269264296920763 1.0 0.2777762512209192 63 Q16539,Q96AY3,Q9C0E8,Q9NZZ3,P04083,P42785,P04792,O00203,Q99439,O75122,P46108,Q16512,Q9HD42 13 +Negative regulation of response to external stimulus 0.4071191706997217 2.2032139123869885 0.0275796751898513 1.0 0.2780852796261996 55 Q16539,P19474,Q9Y3Z3,P14174,Q7Z739,P28070,Q9UMX5,Q96G23,Q9HCK8,Q96J02,P51452,O75122,P46108,Q96KB5,P25786,P80303,P30046 17 +Deoxyribose phosphate catabolic process 0.8031588183679768 2.194612248189122 0.0281914241963487 1.0 0.2794415821976462 6 Q9H773,P00491,P33316,Q9Y3Z3,P13051 5 +Regulation of protein catabolic process 0.3103464433474557 2.192176539753034 0.028366761757657 1.0 0.2803503650771745 140 Q9UJY5,P62191,Q99497,P26038,O43242,Q9H2J4,O43847,Q92995,Q9UNN5,O60493,P15311,P07900,Q13200,P24941,Q13526,Q96J02,Q99460,Q15370,Q9GZU8,P48729,P62333,Q13596,P17612,Q96KB5,P17980,P78559,Q05639,Q96PU5,P08238,P62195,Q16850,P49841,P40818,O75832,P61289,Q9GZP4,Q9NZJ0,Q9UKS6,Q7Z6Z7,P46934,Q9UL46,P62081,Q9UMY4,P54727,P10398,P54725,P19784,O94966,O14965,Q04323,Q8IYU2 51 +Escrt complex disassembly 0.7552371859832059 2.1887942932087854 0.0286117947106765 1.0 0.2823487286418858 7 Q9NZZ3,Q9UN37,P53990,Q9HD42 4 +One carbon metabolic process 0.6316557364566621 2.184319310140179 0.0289387927993671 1.0 0.2851487625312831 13 O43865,P00374 2 +Protein transport along microtubule 0.8545085539674785 2.1717409686764007 0.0298752064990153 1.0 0.2912791673903723 5 P04792,O95817 2 +Pyrimidine deoxyribonucleotide metabolic process 0.797645120897822 2.1705832721760903 0.0299626876989518 1.0 0.2912791673903723 6 Q9H773 1 +Protein deneddylation 0.704995692019986 2.16710908186741 0.0302265375951567 1.0 0.2912791673903723 8 Q9UBW8,Q92905,Q7L5N1,Q9UNS2 4 +Jnk cascade 0.5498439389803743 2.161890631825899 0.0306266072717495 1.0 0.2912791673903723 21 P09429,P46109,P98170,P43034,P31689,Q53EL6,P51452,Q96J02,Q92905,Q13546 10 +Response to transforming growth factor beta 0.4402100679751615 2.160244039111735 0.0307537825727899 1.0 0.2912791673903723 38 P62942,Q96AC1,O14737,Q9UNH7,Q13526,P04150,P46108,Q8WUH2 8 +Glutathione metabolic process 0.5552027044735723 2.1551214585207727 0.0311523309283132 1.0 0.2933926037028342 20 Q04760,P28161,O75874,P21266 4 +Nucleoside monophosphate metabolic process 0.436061402270499 2.146664853604203 0.0318199727472015 1.0 0.2958494504224996 39 P22102,P04818,P55263,P04183,P30520,P23919,P31939,Q01433,P34896,P60891,P07741,O43598,P11172,Q9UDY2,Q06203,Q9Y3D8,Q9P2T1,P00491,P33316,P11908,P49915 21 +Pteridine containing compound metabolic process 0.5589754757484602 2.1400440637134097 0.032351205898472 1.0 0.2991011911398707 19 P00374,P35270 2 +Pteridine containing compound biosynthetic process 0.6767352885712168 2.136919269332586 0.0326045584350205 1.0 0.2997618538405234 9 P00374 1 +Positive regulation of protein polymerization 0.4610244879817073 2.133541955435498 0.0328802937556582 1.0 0.3008487996388465 31 Q7Z460,P46821,Q15691,P42345,P36405,P62330,P07737,P35080,Q14203,Q9UQB8,P23396,Q16512,O95429,P07900 14 +Pyridine containing compound biosynthetic process 0.8445516955441712 2.1304602310105323 0.0331336357461675 1.0 0.3016808381750505 5 Q9BQG2 1 +Folic acid containing compound metabolic process 0.5863855675553563 2.10684039623371 0.0351314165775324 1.0 0.3172590801490937 15 P00374 1 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.5848599152283609 2.097827056859084 0.035920425465967 1.0 0.3203871949307952 15 Q9UN37,Q9NZZ3,Q92783,P46934,Q9HD42 5 +Regulation of transporter activity 0.4055002908050545 2.0899681385813613 0.0366206618953421 1.0 0.3218712042854609 49 Q99497,P62942,Q12955,Q9P2B4,Q9HD26,Q9H4A3,P27695,P17612,P42858,Q96PU5,O43865,Q9UHD1,P46934,Q13546,Q00535,P28161,Q04917,O95747,P0DP25 19 +Protein k48 linked ubiquitination 0.5987919335041111 2.0875698914966576 0.0368366503212085 1.0 0.322908509198679 14 P49427,Q8IYU2,Q13309,Q96J02,Q15386,Q8TDB6,Q96PU5 7 +Axonal transport 0.5093040320022753 2.0866930257928944 0.0369158921056707 1.0 0.3231733874642513 25 Q9Y496,P27695,P04792,O00203,P43034,Q12756,Q14203,Q9NZ32,P07196,P78559,Q9UL25,O14617,Q92572 13 +Syncytium formation 0.6664674051672759 2.084818076822983 0.0370858172054089 1.0 0.3233726283307614 9 Q16539 1 +Anterograde axonal transport 0.5552671394227736 2.0799462028918865 0.0375304675325141 1.0 0.3242474993110523 18 Q9Y496,P27695,P04792,O00203,P07196,P78559,Q9UL25,O14617,Q92572 9 +Modification of postsynaptic actin cytoskeleton 0.8307809307370637 2.0730816200376876 0.0381646842298997 1.0 0.3267789023703905 5 Q9UQB8,P07737 2 +Endosomal transport 0.371179751857637 2.073019417437093 0.0381704725159588 1.0 0.3267789023703905 81 Q9UJY5,Q9UBC2,Q9UN37,O75351,O75436,O15260,Q9UID3,Q14203,Q15075,Q9NZZ3,Q15036,O60271,Q9UNH7,Q13596,Q8IWJ2,O00203,Q92783,Q4J6C6,Q9C005,Q9Y5X3,O14617,Q9HD42,O60749 23 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4803668848437465 2.0631240919365883 0.0391008397452541 1.0 0.3307235260237975 28 P08238,P62081,Q99497,Q9H2J4,Q9UL15,O15372,O00560,P19784,O94966,P78559,Q96KB5,P60520,P54578,Q04323,Q9GZU8 15 +Tissue regeneration 0.828140357083142 2.062041672436592 0.0392037686830168 1.0 0.3308978785639531 5 P04083,P52294 2 +Regulation of muscle cell differentiation 0.5209908725426584 2.0573477869658614 0.0396527837352802 1.0 0.3342597830984238 23 Q16539,P67809,Q53EL6 3 +Negative regulation of muscle cell differentiation 0.635585764439613 2.0532602078139384 0.0400473479139329 1.0 0.3363821901882063 11 P67809 1 +Neuron apoptotic process 0.3941193203154487 2.0508372175385117 0.0402828018233498 1.0 0.3375730632847455 54 P06744,P49427,Q01105,O43813,P98170,Q99720,Q9UNH7,Q96B36,O95831,P51858 10 +Rna stabilization 0.4687874553166734 2.043275432273603 0.0410251801871051 1.0 0.3380087290015286 29 Q16539,P16989,Q96HR8,P67809,Q9H814 5 +Negative regulation of potassium ion transport 0.8618058886386192 2.041500714392801 0.041201082938139 1.0 0.3380087290015286 4 Q12955,Q96PU5 2 +Negative regulation of potassium ion transmembrane transport 0.8618058886386192 2.041500714392801 0.041201082938139 1.0 0.3380087290015286 4 Q12955,Q96PU5 2 +Negative regulation of sodium ion transport 0.8232030986731829 2.041367501402528 0.0412143122017916 1.0 0.3380087290015286 5 O95747,P46934,Q96PU5 3 +Positive regulation of endothelial cell proliferation 0.5753266693802964 2.0413162510316343 0.0412194027889278 1.0 0.3380087290015286 15 Q9H2J4 1 +Dendritic spine development 0.5024789232230931 2.037871082525488 0.0415628272379406 1.0 0.3395070101022367 25 P61160,Q9NUL3,Q13177,Q00535,P23528,Q96HC4,P43034,P62330,Q12756,Q14012,P78344,Q9UQB8,O60678,Q15334,Q06787 15 +Meiotic cell cycle checkpoint signaling 0.8604608556932678 2.0360307140510128 0.0417472712019382 1.0 0.3397157178945753 4 O60921,P33981 2 +Positive regulation of cytoskeleton organization 0.3983800547757561 2.032518771943532 0.0421011653549205 1.0 0.3408869079119549 50 Q15691,P42345,O75351,P35080,Q14203,Q16512,O95429,Q9UHV9,Q96AC1,Q9H6U6,P07737,Q9UQB8,P23396,O60504,P48681,P36405,Q00535,P46821,P60981,P62330,Q6UVJ0,Q7Z460 22 +Translational initiation 0.3672233027436591 2.026866276039942 0.0426760902465102 1.0 0.3426562568879358 70 Q9Y6E2,Q14232,P42345,P20042,P60228,Q9UBQ5,O75822,P78344,P61221,O75794,P61247,P23588,Q6PKG0,Q9NR50,Q14240,Q9BPZ3,Q15056,Q9ULC4,P23396,P19525,P46199,O75821,Q14152,P04792,Q04637,P60842,O15371,P49770,Q9Y5A9,O60841,Q9Y262,Q7Z739,P55010,Q13144,Q7L1Q6,P55884,P08708,Q92905 38 +Inflammatory response to antigenic stimulus 0.6289719211298918 2.0180140239810833 0.0435898007931103 1.0 0.3481736874841394 11 P09429,Q16539,P28070 3 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.9734151329243363 2.0177458384481173 0.0436177382401399 1.0 0.3481736874841394 2 Q9BQG2 1 +Negative regulation of jnk cascade 0.7619842902111601 2.013692244248635 0.0440418548076846 1.0 0.3500342256900168 6 Q53EL6,P31689,P51452,Q96J02 4 +Phospholipid dephosphorylation 0.7170231146348607 2.011317338013922 0.0442919483038413 1.0 0.3500342256900168 7 Q13614,P34913 2 +Regulation of axonogenesis 0.473570808251978 2.0109862558172695 0.044326908478927 1.0 0.3500342256900168 28 P46821,Q02750,P53990,P49841,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q16512,Q8N0X7,Q00535 12 +Trna modification 0.4300746637199255 2.0079405320151036 0.0446496113866381 1.0 0.3500342256900168 35 Q9UI30,Q96SZ6,Q7Z4G4,Q9NXH9,Q8WWH5,Q9NX74,Q9UBP6,Q9UJA5,Q9NXG2,Q9H9T3,Q969Y2,P05455 12 +Cellular aldehyde metabolic process 0.5202979679476096 2.007908475460007 0.0446530183791158 1.0 0.3500342256900168 22 Q04760,P48735,O75874 3 +Nucleoside monophosphate biosynthetic process 0.4901047618802636 2.0073719281806417 0.0447100755508182 1.0 0.3500342256900168 26 P11172,Q9BZX2,P22102,P04818,P55263,P04183,Q06203,P00492,P33316,P30520,P22234,P07741,P31939,Q01433,P34896,P11908,P49915,P60891 18 +Glyoxylate metabolic process 0.991234735487615 1.99583935313476 0.0459514117522266 1.0 0.3552514540279883 3 P48735 1 +Cytoplasmic sequestering of protein 0.636719405297697 1.9943150946274917 0.0461176306726605 1.0 0.3559805871126206 10 Q9HD26,O75832,Q9UN86,O00221,P31946,Q9UNN5 6 +Regulation of syncytium formation by plasma membrane fusion 0.7570089846627799 1.9916031692377305 0.046414615379339 1.0 0.3561875955536701 6 Q16539 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.7570089846627799 1.9916031692377305 0.046414615379339 1.0 0.3561875955536701 6 Q16539 1 +Regulation of inflammatory response 0.4205668000478237 1.9842117888065929 0.0472322348942633 1.0 0.3589139538404794 38 Q16539,P98170,P04083,P60900,P28070,Q53EL6,Q9UNH7,Q96KB5,P25786 9 +Regulation of response to oxidative stress 0.5166205036503434 1.982963668472835 0.0473714879279949 1.0 0.3589139538404794 22 P00374,O43813 2 +Protein export from nucleus 0.4695907554653202 1.9803408503675632 0.0476652415157672 1.0 0.3598832463750303 28 Q99497,P49841,Q9UIA9,P55060,Q9H6Z4,O95817,Q06124,O43865,Q9HAV4,Q14012,Q9C0E2,P62826,Q9UHD1,Q92688,Q00535 15 +Pyridine containing compound catabolic process 0.8467898481724226 1.9802767012626767 0.0476724453063808 1.0 0.3598832463750303 4 Q13126,Q9BQG2 2 +Cellular response to vascular endothelial growth factor stimulus 0.6668496158936928 1.9789080728708373 0.0478263571830437 1.0 0.3602724344106421 8 Q16539,P04083 2 +Positive regulation of alpha beta t cell differentiation 0.8077389529265614 1.9763464618369544 0.0481155507623924 1.0 0.36140954795623 5 O00203,P04083,O14617 3 +Vesicle transport along microtubule 0.5919581121417834 1.9628334740468911 0.0496655268667358 1.0 0.367859722590475 13 Q9Y496,P27695,P43034,O00203,Q12756,O14617,Q92572,P42858 8 +N terminal protein amino acid modification 0.6422741702606168 1.960914852835347 0.0498889563952786 1.0 0.3688055010658212 9 P41227,Q86UY6,Q9BV86,Q5VZE5 4 +Positive regulation of cation channel activity 0.6632136544155428 1.9607763906378992 0.0499051133116978 1.0 0.3688055010658212 8 P28161,Q00535,Q12955,P0DP25,P42858 5 +Cytoplasmic sequestering of transcription factor 0.7496863863915436 1.959005769679144 0.0501121110948197 1.0 0.3699205334121518 6 O00221,O75832,Q9UN86,Q9UNN5 4 +Positive regulation of peptidyl serine phosphorylation 0.5247496550645051 1.9565994576526784 0.0503945788402928 1.0 0.3715895567284233 20 P08238,Q99497,Q9NYB0,P10398,Q13043,P35080,Q14012,P14174,Q16512,O95429 10 +Regulation of antigen receptor mediated signaling pathway 0.7485007923359378 1.9537183030171552 0.0507345405211387 1.0 0.3728922596357975 6 P15311,P51452,P23396,O95999 4 +Dendrite development 0.3798479674538664 1.9532369012433803 0.0507915303900419 1.0 0.3728922596357975 57 Q6SZW1,O43815,Q9UQB8,P46821,P46109,P78559,P49841,Q9Y296,Q86X55,Q9Y4F1,Q14012,O43251,P46108,O60678,P46934,Q96PU5 16 +Tetrahydrobiopterin metabolic process 0.8378244539114339 1.9435612013918149 0.0519483883741087 1.0 0.3783626774483339 4 P00374 1 +Pyridine nucleotide biosynthetic process 0.9730569240934024 1.9266499767820575 0.054023265864924 1.0 0.3875096502519903 3 Q9BQG2 1 +Protein localization to presynapse 0.8325941607152301 1.9220873546271833 0.0545947669503688 1.0 0.3884283284326834 4 P04792 1 +Axo dendritic protein transport 0.8325941607152301 1.9220873546271833 0.0545947669503688 1.0 0.3884283284326834 4 P04792 1 +Modification of postsynaptic structure 0.6973331455306908 1.918600759784832 0.0550348793767296 1.0 0.3884283284326834 7 Q9UQB8,P07737 2 +Trna transport 0.793182343994246 1.914779848076644 0.0555205854985461 1.0 0.3884283284326834 5 P67809,P05455 2 +Alcohol biosynthetic process 0.4103985212790587 1.9135423740087192 0.0556786542346143 1.0 0.3884283284326834 39 P00374,Q16850,Q15392,Q15125,Q9UBM7 5 +Multivesicular body organization 0.5386397699023175 1.9115756586457988 0.0559306439266293 1.0 0.3884283284326834 16 Q9UN37,P53990,Q9NZZ3,Q92783,Q9HD42 5 +Negative regulation of lymphocyte differentiation 0.791693127581388 1.908461958068124 0.0563315354947884 1.0 0.3884283284326834 5 P04083,O15347 2 +Synaptic vesicle endosomal processing 0.8289505902472947 1.907104694644822 0.0565070314512636 1.0 0.3888036084973319 4 O00203,O14617 2 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.384529012388893 1.9056445797045636 0.0566963341265307 1.0 0.388866588899542 51 Q16539,P62942,P98170,P33981,Q96AC1,Q53EL6,Q13526,Q93062,Q8N0X7,Q8WUH2 10 +Skeletal muscle tissue regeneration 0.8284489306056977 1.9050403392016255 0.0567748276443498 1.0 0.388866588899542 4 P52294,P04083 2 +Negative regulation of ryanodine sensitive calcium release channel activity 0.7907199786075482 1.9043315373849008 0.0568670193718383 1.0 0.388866588899542 5 P0DP25,P28161 2 +Positive regulation of sequestering of calcium ion 0.7907199786075482 1.9043315373849008 0.0568670193718383 1.0 0.388866588899542 5 P0DP25,P28161 2 +Negative regulation of sodium ion transmembrane transport 0.8277065530507441 1.9019847584806095 0.057173147204615 1.0 0.3896971976745607 4 P46934,Q96PU5 2 +Positive regulation of calcium ion transmembrane transport 0.607356619493521 1.901953311985399 0.0571772585613459 1.0 0.3896971976745607 11 P42858,P27695,P28161,P0DP25,Q00535 5 +Vascular endothelial growth factor receptor signaling pathway 0.6072890851660373 1.9015886526529575 0.057224952571143 1.0 0.3896971976745607 11 P04792,Q16539 2 +Regulation of response to extracellular stimulus 0.7887767045753631 1.8960790349975096 0.0579495943745018 1.0 0.3935147872217329 5 Q9UMX5 1 +Proteasome assembly 0.6925528169986819 1.8959653035816737 0.0579646326444633 1.0 0.3935147872217329 7 Q9BT73,Q969U7,O00231,O95456,O75832 5 +Regulation of alpha beta t cell activation 0.6176876538917295 1.8940655933920825 0.0582163039476584 1.0 0.3944109718632726 10 P09429,O00203,P04083,Q96J02 4 +Synaptic vesicle cytoskeletal transport 0.7879653558709168 1.892631713452673 0.0584068632797207 1.0 0.3948903002460711 5 O00203,O14617 2 +Regulation of collateral sprouting 0.94274028629857 1.89153428643843 0.0585530585766993 1.0 0.3949365937101385 2 Q8N0X7 1 +Phosphatidylethanolamine biosynthetic process 0.962987451555906 1.8881754225728495 0.0590024041448149 1.0 0.3956702422407122 3 P35790 1 +Cellular response to hydrogen peroxide 0.5141985143146958 1.886948087506624 0.0591673083290644 1.0 0.3957723882832712 20 Q99497,Q99720,P04083,P12004,P27695,Q13131,Q9P289,P23396,Q13546,O95831,P06493 11 +Cellular oxidant detoxification 0.5134170653630084 1.881772513515852 0.0598669093142336 1.0 0.3990320184018486 20 P28161,P00374,Q6DKJ4,P00390 4 +Regulation of striated muscle cell differentiation 0.6034998906298658 1.8811085496536797 0.0599571542227796 1.0 0.3992298592288523 11 Q16539,P67809 2 +Positive regulation of alpha beta t cell activation 0.6887959013451534 1.878142118743515 0.0603617257999338 1.0 0.400306334480044 7 O00203,P04083,O14617 3 +Vesicle mediated transport between endosomal compartments 0.5009684695383951 1.8761710490101369 0.0606317961070748 1.0 0.401693266269183 22 Q15075,Q13614,P26038,Q02750,Q99570,O75165,Q9UMY4,Q8NEB9,P36507,Q86VS8,O60493,P15311,P35241 13 +Response to toxic substance 0.3812010282861782 1.8714674141320633 0.0612803224168163 1.0 0.4046563398093867 51 P46821,P00374,P00390,P34913,Q6DKJ4,P28161,P21266,P07196,O95831 9 +Detoxification 0.454987563585624 1.867220546472495 0.0618707954887647 1.0 0.40645231443558 28 P00374,P00390,P28161,Q6DKJ4,P21266 5 +Regulation of potassium ion transmembrane transporter activity 0.6002211171136895 1.8633558635085776 0.0624122153582238 1.0 0.4077515596049668 11 Q12955,P46934,Q96PU5 3 +Retina homeostasis 0.8178706018341673 1.861427223680948 0.062683869081765 1.0 0.4084651857817194 4 P04792,Q15051 2 +Actomyosin structure organization 0.379904908037151 1.858135373421785 0.0631497926447701 1.0 0.4105359300930226 51 Q9UN37,Q16527,Q96AC1,P07737,Q15417,P35080,Q99439,O75122,P16949,Q16512,O60504 11 +Negative regulation of transmembrane transport 0.4773336957094503 1.856156736762736 0.0634312206448113 1.0 0.4115079124660944 25 Q9P2B4,P62942,P0DP25,P28161,Q12955,P46934,Q96PU5 7 +Pyrimidine containing compound biosynthetic process 0.5248697716140395 1.855014237815092 0.0635941934311001 1.0 0.4115079124660944 17 P15531,P11172,P33316,P23919,P22392,Q9NRF8,P17812,P60891 8 +Positive regulation of actin filament polymerization 0.5721607181757857 1.8505459283905128 0.0642349047944474 1.0 0.4141513569171388 13 P42345,P62330,P07737,P35080,Q9UQB8,O95429 6 +Nucleotide excision repair 0.4971419470586078 1.8499145031839912 0.0643258732003975 1.0 0.4141513569171388 22 Q07864,Q96T76,P41208,P35244,P54727,O95251,P54725,O60921 8 +Regulation of transposition 0.9319310546304456 1.8468316269905984 0.0647715465927751 1.0 0.4149017475934372 2 Q5TAX3 1 +Transposition rna mediated 0.9319310546304456 1.8468316269905984 0.0647715465927751 1.0 0.4149017475934372 2 Q5TAX3 1 +Transposition 0.9319310546304456 1.8468316269905984 0.0647715465927751 1.0 0.4149017475934372 2 Q5TAX3 1 +Regulation of gastrulation 0.8141693306504503 1.8461306284336312 0.0648732405870218 1.0 0.4149017475934372 4 O75122,O95747 2 +Regulation of proteasomal protein catabolic process 0.3527312787773177 1.8460059723696527 0.0648913382537672 1.0 0.4149017475934372 74 P62191,Q99497,O14980,Q92995,P43686,P24941,P60520,Q15370,P54578,Q9GZU8,P48729,P62333,P17612,Q96KB5,P78559,P17980,Q9NZL4,P08238,P62195,P49841,O75150,O75832,P61289,Q9GZP4,Q9UL46,P54727,P10398,Q9UL15,P54725,O94966,O14965,Q9Y5A7,Q04323 33 +Peripheral nervous system axon regeneration 0.8133669339827687 1.842812019907364 0.0653564612324824 1.0 0.4162606690285256 4 P46821,Q96G23 2 +Regulation of t cell receptor signaling pathway 0.7757309941520543 1.84052508594302 0.0656911847795147 1.0 0.4179886969754451 5 P15311,P51452,P23396,O95999 4 +Immune response regulating cell surface receptor signaling pathway 0.4595798826224261 1.8397524193484136 0.0658045938113784 1.0 0.418306540409457 27 P49770,P46109,Q14232,O95999,Q9H4A3,Q9NR50,Q13177,P15311,Q13144,P51452,P23396,Q16512 12 +Regulation of protein export from nucleus 0.5217411278563411 1.8351695025173285 0.0664805783963555 1.0 0.4207699416128518 17 Q99497,O14980,P49841,O95817,Q06124,Q14012,Q9C0E2,P17612,Q92688,Q00535 10 +Non lytic viral release 0.6381597201190489 1.8349623508382775 0.066511268076546 1.0 0.4207699416128518 8 Q9NZZ3,Q9UN37,Q9HD42 3 +Positive regulation of epithelial cell proliferation 0.4586343506194049 1.8325460351127325 0.0668701097368771 1.0 0.4222296584152241 27 Q9H2J4,P15531,P09429,P22392 4 +Interleukin 8 production 0.6058273947763901 1.8311041315207903 0.067085001987349 1.0 0.4224431134692552 10 P09429,P04083,Q13546,O95999 4 +Viral budding 0.5687134475031258 1.8308757840436904 0.0671190855430645 1.0 0.4224431134692552 13 P46934,Q9NZZ3,Q9UN37,Q9HD42 4 +Positive regulation of protein containing complex assembly 0.3658876678272938 1.820725116914469 0.0686486521830498 1.0 0.430355917494502 58 O15144,Q15691,P17931,Q99497,P42345,P35080,Q14203,Q16512,O95429,P62333,Q96AC1,Q13535,P07737,Q9UQB8,P23396,P49841,P36405,Q9BPX3,Q04637,P46821,Q86VP6,P62330,Q7Z460,P07900,Q9UNN5 25 +Regulation of protein folding 0.8075569595733585 1.8187568208133953 0.0689485386464698 1.0 0.4312227388591361 4 Q9H2J4 1 +Negative regulation of developmental growth 0.6023477789345049 1.812563589709738 0.0698991578299914 1.0 0.4340421287242155 10 Q8N0X7,O60271,Q13043,Q9P265 4 +Regulation of inclusion body assembly 0.6136625833541678 1.812389181767312 0.0699260832380335 1.0 0.4340421287242155 9 P49427,P62195,P62333,P25685,O75190 5 +Interleukin 2 production 0.6746092751253555 1.8105774743765957 0.0702062816663793 1.0 0.4353714099198236 7 P23396,P04083,P00491 3 +Negative regulation of rna catabolic process 0.4094958611574443 1.809587730939202 0.0703597439736205 1.0 0.4356708053750489 34 Q16539,P16989,Q96HR8,P67809,Q9H814 5 +Cell adhesion mediated by integrin 0.6330132045635981 1.808934131746383 0.0704612370352228 1.0 0.4357227716099336 8 Q9H4A3,P46108,P46109 3 +Negative regulation of cell aging 0.7161399427250086 1.8083899604726803 0.0705458293580296 1.0 0.4358370263618852 6 P67809,Q00534 2 +Regulation of ryanodine sensitive calcium release channel activity 0.6738011052875217 1.806716298228144 0.0708065251604039 1.0 0.4369981899056822 7 P0DP25,P28161 2 +Microtubule anchoring at microtubule organizing center 0.7153197834310943 1.804682298349944 0.0711244113981499 1.0 0.438179551342621 6 P49841,Q8TD16,Q86VS8,Q14203 4 +Tricarboxylic acid cycle 0.4901356336222307 1.8016945448721176 0.0715934768344035 1.0 0.4398361596387587 22 P48735 1 +Schwann cell proliferation 0.9199532573765754 1.7971713964372296 0.0723084139823799 1.0 0.4408487321273428 2 Q96G23 1 +Negative regulation of schwann cell proliferation 0.9199532573765754 1.7971713964372296 0.0723084139823799 1.0 0.4408487321273428 2 Q96G23 1 +Inclusion body assembly 0.5878225101089481 1.7959674829233687 0.0724996886981304 1.0 0.441290810616875 11 P49427,P62195,P62333,O95817,P25685,O75190 6 +Regulation of response to wounding 0.494737585040478 1.7940256208400742 0.0728090795326497 1.0 0.4427651773793605 21 P04083,Q96AC1,Q96G23,O75122,P46108 5 +Positive regulation of calcium ion transmembrane transporter activity 0.6299078315798845 1.7931996329012858 0.0729410087773938 1.0 0.4429328878638246 8 P42858,P0DP25,P28161,Q00535 4 +Adaptive immune response 0.3793210181685389 1.792818991235086 0.0730018718048637 1.0 0.4429328878638246 46 Q6P179,Q96FW1,Q9UQ84,P04083,O96028,P13051,Q16512 7 +Positive regulation of release of sequestered calcium ion into cytosol 0.6700671653843207 1.7888600047022374 0.0736373643630829 1.0 0.4449289696438525 7 P0DP25,P28161 2 +Peptidyl arginine modification 0.6288054664101841 1.7876088676985311 0.0738391337933439 1.0 0.4454581681079884 8 Q86X55,Q6P2P2,Q99497,O60678 4 +Regulation of response to food 0.9173239848086532 1.7862538701430952 0.0740581622993419 1.0 0.4454581681079884 2 Q9UMX5 1 +Regulation of appetite 0.9173239848086532 1.7862538701430952 0.0740581622993419 1.0 0.4454581681079884 2 Q9UMX5 1 +Negative regulation of response to food 0.9173239848086532 1.7862538701430952 0.0740581622993419 1.0 0.4454581681079884 2 Q9UMX5 1 +Cell surface receptor signaling pathway involved in cell cell signaling 0.3478612238044639 1.7858076845593005 0.0741304020653008 1.0 0.4454581681079884 81 P30153,P98170,Q92541,O60493,Q9GZS3,Q13043,Q13526,Q16539,P48729,Q96K76,Q9H4A3,Q99471,Q96AC1,Q9UQB8,Q96AQ6,O43815,P49841,Q6DKJ4,P40818,Q9HCK8,Q15042,Q00535,Q13614,P52294,Q13283 25 +5 phosphoribose 1 diphosphate metabolic process 0.7619883040935733 1.7817244901784308 0.0747941711555606 1.0 0.4461053098530795 5 P11908,P06737,Q14558,P60891 4 +Neutrophil clearance 0.9161554192229092 1.7813998110625728 0.0748471590863897 1.0 0.4461053098530795 2 P04083 1 +Negative regulation of alpha beta t cell differentiation 0.9161554192229092 1.7813998110625728 0.0748471590863897 1.0 0.4461053098530795 2 P04083 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.9161554192229092 1.7813998110625728 0.0748471590863897 1.0 0.4461053098530795 2 P04083 1 +Neutrophil homeostasis 0.9161554192229092 1.7813998110625728 0.0748471590863897 1.0 0.4461053098530795 2 P04083 1 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.9161554192229092 1.7813998110625728 0.0748471590863897 1.0 0.4461053098530795 2 P04083 1 +Regulation of tolerance induction 0.9161554192229038 1.7813998110625495 0.0748471590863935 1.0 0.4461053098530795 2 Q96J02 1 +Regulation of glial cell proliferation 0.7599431524076241 1.772950364429156 0.0762369320157154 1.0 0.4493118707695996 5 Q96G23 1 +Positive regulation of monooxygenase activity 0.6666544129555156 1.7725158740835734 0.0763089626160238 1.0 0.4493118707695996 7 P00374 1 +Negative regulation of meiotic cell cycle 0.9135261466549812 1.7704741494561842 0.0766481870263215 1.0 0.449523886901701 2 P33981 1 +Regulation of dna directed dna polymerase activity 0.5941790499260016 1.7689191110480864 0.0769073744139974 1.0 0.4506430330107298 10 Q9Y248,Q9BRT9,P12004,P40938,P40937 5 +Oligodendrocyte development 0.6051372268820145 1.7677370086623834 0.0771048799318618 1.0 0.450998552360988 9 P18074,P49770,Q14232,Q9NR50,Q13144,Q96P11 6 +Negative regulation of actin filament bundle assembly 0.6645959367242967 1.76264669878698 0.0779600956837311 1.0 0.4543881085297577 7 O75122,P16949,P07737,Q7Z460 4 +Nucleotide sugar metabolic process 0.5146542072678871 1.7615376745340037 0.0781474422457377 1.0 0.4545621133993307 16 Q13630,Q9NR45,P34949,Q9Y5P6,Q16222,Q06210,Q86W56,Q9Y223,Q8NBZ7,O60701,Q16851 11 +Oocyte differentiation 0.5689829773473074 1.7552866266503304 0.0792102928191735 1.0 0.4568278654978059 12 Q9Y5A9,P30153,Q15645,Q5TAX3,Q8N2A8,Q9BQA1 6 +Abscission 0.791104875575688 1.7504005934660605 0.080049213692825 1.0 0.4591153618813757 4 P53990,Q8N0X7 2 +Regulation of dephosphorylation 0.3921909670122144 1.7455997238798076 0.0808805302755502 1.0 0.4615966732754551 39 Q13614,Q8IV63,P17931,P62942,P08238,Q15257,P49841,O43768,P0DP25,Q5H9R7,Q14738,Q13526,Q9UHD1,Q15435,O95429,P78318,P31946,P42858 18 +Positive regulation of fat cell differentiation 0.7019500709085638 1.7440809782665765 0.0811449704222324 1.0 0.4615966732754551 6 Q16539,Q86X55,Q13043 3 +Long chain fatty acid transport 0.5531772534188741 1.7418147093198375 0.0815408719894765 1.0 0.4615966732754551 13 O43772 1 +Midbody abscission 0.6001135092881669 1.741344006983006 0.0816232966976744 1.0 0.4615966732754551 9 Q9NZZ3,Q9UN37,Q9HD42 3 +Regulation of membrane depolarization 0.6195045089283531 1.7403309027148537 0.0818009307664944 1.0 0.4615966732754551 8 Q96PU5 1 +Purine nucleoside monophosphate biosynthetic process 0.5250868612042533 1.7383579443044803 0.0821477622037973 1.0 0.4615966732754551 15 P22102,P55263,Q06203,P00492,P30520,P22234,P07741,P31939,Q01433,P11908,P49915 11 +Cellular protein catabolic process 0.341819552625721 1.737452690804823 0.0823072976745304 1.0 0.4615966732754551 264 Q9H2J4,O75351,P49721,P28070,Q13200,Q96E52,Q15370,Q96K76,P20618,Q96PU5,Q4G0X4,Q96RU2,O75832,P46934,Q13546,Q9HD42,P54727,P28072,P10398,Q13309,P49720,Q04323,Q8IYU2,Q9UBU6,Q93034,Q99497,O95155,Q92995,Q8WW12,P15311,Q9H1I8,P28074,P24941,P48729,Q9NZZ3,Q8N511,Q8N3C0,P60900,Q96KB5,P25788,P08238,Q99436,Q13107,P68036,P61289,Q9GZP4,Q7Z6Z7,Q8NBM8,P28066,Q8TDB6,P49427,P62081,Q9UNS2,Q96RL7,O95260,O14965,Q9UN37,P51665,Q6NTF9,Q15008,Q96J02,Q99460,P48556,Q9GZU8,Q9H9H4,P62333,Q16763,P63208,O14773,Q9NXV2,P17612,P17980,P78559,P62195,P25789,Q93008,Q92783,Q15386,Q9UBV2,P54725,P19784,O94966,P25786,P07900,O43242,P62191,P26038,Q9UNM6,Q5T4S7,Q9UHG3,Q86Y37,P25787,P49841,P40818,Q9NZJ0,Q9UL46,Q9Y5X3,O94888,Q9UNN5 99 +Regulation of glial cell migration 0.905054046158347 1.735232745730535 0.0826995886217176 1.0 0.4615966732754551 2 Q96G23 1 +Diapedesis 0.9050540461583448 1.735232745730525 0.0826995886217194 1.0 0.4615966732754551 2 P46108 1 +T cell extravasation 0.9050540461583448 1.735232745730525 0.0826995886217194 1.0 0.4615966732754551 2 P46108 1 +Cellular response to toxic substance 0.438016943725188 1.7345105882002425 0.0828275287160964 1.0 0.4615966732754551 28 P00374,P28161 2 +Organic hydroxy compound metabolic process 0.317175376448702 1.734319679987621 0.0828613775135189 1.0 0.4615966732754551 117 P48735,P00374,P34913,O75874,Q16850,Q15392,P35270,Q15125,Q9UBM7 9 +Energy reserve metabolic process 0.501181414019137 1.7337049144366754 0.0829704541075151 1.0 0.4615966732754551 18 P13807,P06737,P31751,P42345,P49841,P08237,Q06210,P35573,P46976,Q16851 10 +Positive regulation of nitric oxide synthase activity 0.7503658555318768 1.7317834514420365 0.0833121256607243 1.0 0.4615966732754551 5 P00374 1 +Deoxyribonucleotide biosynthetic process 0.6579871269748301 1.7309071258933872 0.0834683304830594 1.0 0.4615966732754551 7 P31350,P33316,P04818,P55263,P23919,P23921 6 +Deoxyribonucleoside monophosphate metabolic process 0.6579871269748271 1.7309071258933748 0.0834683304830616 1.0 0.4615966732754551 7 O43598,P00491,P33316,P55263,P04818,P04183 6 +Rna phosphodiester bond hydrolysis endonucleolytic 0.4037667178780038 1.7290193788252797 0.0838056268211788 1.0 0.4620884551146442 32 Q96F86,Q9UQ84,Q8N2A8,Q2NL82,Q9BQG2,Q9UPY3,Q99598 7 +Negative regulation of ubiquitin dependent protein catabolic process 0.4599560490827445 1.7290094138296737 0.0838074102570505 1.0 0.4620884551146442 25 P08238,P62081,Q99497,Q9H2J4,Q9UL15,O15372,O00560,P19784,P78559,Q96KB5,P54578,Q04323 12 +Negative regulation of neuron projection development 0.4795994085031081 1.7288440728087953 0.0838370058345676 1.0 0.4620884551146442 22 Q9UL15,P43034,P62330,Q96G23,Q14195,Q86X55,Q9P265,Q02790,Q8N0X7,Q00535 10 +Organic cyclic compound catabolic process 0.3088802352273565 1.728057883664538 0.0839778472735655 1.0 0.4620884551146442 182 Q9H773,P34913,Q96C86,P51114,Q9BQ61,P16930,Q969T7,Q96HR8,P67809,Q9H814,Q16539,Q6SZW1,Q5TAX3,Q13126,Q9BQG2,Q14011,P16989,P05455,Q96Q15,Q9HCE1,Q9UKK9,P13051 22 +Regulation of anatomical structure morphogenesis 0.2960613647445148 1.7268272359246823 0.0841986955207612 1.0 0.4625315007273815 159 Q9H2J4,O75400,Q8N2A8,P15311,Q9UEE9,Q96E52,P46108,Q16512,Q6SZW1,Q02750,P04083,Q96AC1,O60271,Q9P258,O95487,Q9Y2J2,Q9UQB8,Q96PU5,P53990,P46109,P49841,Q13177,P04792,Q9NUQ9,Q27J81,Q7Z6Z7,P46934,Q00535,P46821,P49591,Q9HCE1,Q9Y3D6,Q04917,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,O75122,O95747,Q7Z460,Q8N0X7 43 +Cytoplasmic sequestering of nf kappab 0.7850530471518457 1.7251709234436812 0.0844966740622372 1.0 0.4629956751201045 4 O75832,Q9UNN5 2 +Regulation of cell projection organization 0.2939749156360754 1.7247965858269068 0.0845641372640482 1.0 0.4629956751201045 131 Q16658,Q32P28,O15144,Q9UL25,P42345,P51114,Q9NVG8,O60493,P15311,Q4KMP7,Q12756,Q9H4M9,P78344,P27816,P46108,P35080,Q16512,Q12792,Q06787,Q6SZW1,Q02750,P50570,P50395,P27695,Q9H6U6,Q9UHD8,P07737,Q96G23,Q9P258,Q14012,Q9UQB8,Q96PU5,P42858,P53990,P46109,P49841,P08670,Q13177,P23528,P35241,Q14195,Q02790,Q9NT62,P46934,P11233,Q00535,P46821,Q15555,Q9HCE1,Q8TC07,Q9NUL3,Q9NQT8,Q04917,Q96HC4,P43034,P62330,Q9UIW2,Q86X55,P07196,Q9P265,Q9UL15,Q9NZQ3,Q66K14,Q6IBS0,Q8N0X7 65 +Protein localization to synapse 0.5747181755959677 1.7243187026491344 0.0846503247882748 1.0 0.4630829385927865 11 P04792,P78559,Q9UQB8 3 +Regulation of release of sequestered calcium ion into cytosol 0.5497486332820879 1.722072834602372 0.0850563253795693 1.0 0.4644649530665177 13 P0DP25,P62942,P28161 3 +Pigment granule organization 0.7478829037778018 1.721090177181561 0.0852344614753717 1.0 0.4644649530665177 5 O00203,O14617 2 +Negative regulation of calcium ion transport into cytosol 0.6968165913086788 1.720733699512931 0.0852991582471658 1.0 0.4644649530665177 6 P0DP25,P28161 2 +Regulation of chemotaxis 0.4358567720825834 1.7175297302437305 0.0858824271232145 1.0 0.4659684881657138 28 P09429,Q9BVA1,Q9H4A3,P04792,P51452,Q9NUQ9,O95747,P30046 8 +Amp biosynthetic process 0.5733553773454755 1.716843537219295 0.086007763693725 1.0 0.4662404127313715 11 P22102,P55263,Q06203,P00492,P30520,P07741,P31939,P11908 8 +Regulation of dendritic spine development 0.5213426562115782 1.715458081803899 0.0862612744331645 1.0 0.4668590484921353 15 Q9NUL3,P43034,P62330,Q12756,Q14012,P78344,Q9UQB8,Q06787 8 +Positive regulation of dendritic spine development 0.5727535710323663 1.7135411359613906 0.0866130322721308 1.0 0.4669358835432007 11 Q14012 1 +Barbed end actin filament capping 0.5610812396096134 1.7110684854296248 0.0870684710044504 1.0 0.4669358835432007 12 P58546,P47755,Q9BPX3,Q9UEY8,P35241,Q6IBS0,Q13045,Q12792 8 +Regulation of nitric oxide synthase activity 0.6136872620961642 1.7106660554429205 0.0871427773525987 1.0 0.4669358835432007 8 P00374 1 +Positive regulation of vasculature development 0.482199171716033 1.7087005432951692 0.0875064334341724 1.0 0.4669358835432007 21 Q9H2J4 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.8986269354367546 1.7084629351565328 0.0875504781643501 1.0 0.4669358835432007 2 O00203 1 +Regulation of nk t cell differentiation 0.8986269354367546 1.7084629351565328 0.0875504781643501 1.0 0.4669358835432007 2 O00203 1 +Nk t cell differentiation 0.8986269354367546 1.7084629351565328 0.0875504781643501 1.0 0.4669358835432007 2 O00203 1 +Meiotic cell cycle phase transition 0.780849189285243 1.707619620783716 0.0877069453028855 1.0 0.4672910820473075 4 O95067 1 +Negative regulation of reproductive process 0.744692987546244 1.7073401203244702 0.087758853090802 1.0 0.4672910820473075 5 P33981 1 +Nucleotide sugar biosynthetic process 0.5811493476613429 1.6989707850132514 0.0893246883834131 1.0 0.4737734824493754 10 Q13630,Q9NR45,P34949,Q9Y5P6,Q16222,Q06210,Q8NBZ7,O60701 8 +Water soluble vitamin metabolic process 0.4806708977215847 1.6982645259281912 0.0894578468454603 1.0 0.4737734824493754 21 P00374 1 +Peptidyl arginine n methylation 0.6917357604707157 1.697584522806881 0.0895862059996335 1.0 0.4737734824493754 6 Q6P2P2,Q86X55 2 +Peptidyl arginine methylation 0.6917357604707157 1.697584522806881 0.0895862059996335 1.0 0.4737734824493754 6 Q6P2P2,Q86X55 2 +Actin filament severing 0.6109763898392635 1.6968178052627023 0.0897311114221115 1.0 0.4739643321270507 8 P60981,Q9Y281,Q9BPX3,P60983,Q13045 5 +Positive regulation of cytoplasmic transport 0.6911521522484674 1.6949229154861276 0.0900900447800769 1.0 0.4747975806495776 6 Q13614,P15311,P35241,P26038 4 +Positive regulation of early endosome to late endosome transport 0.6911521522484674 1.6949229154861276 0.0900900447800769 1.0 0.4747975806495776 6 Q13614,P15311,P35241,P26038 4 +S adenosylmethionine metabolic process 0.6906865479195878 1.69279910003542 0.0904937140616766 1.0 0.4760850463643832 6 O43865,Q9NZL9,Q9BV20 3 +Alpha beta t cell activation 0.531023984143662 1.691271754349534 0.0907849120904482 1.0 0.4772361566987518 14 P09429,O00203,P04083,Q96J02 4 +Regulation of neuron projection development 0.3400398068896854 1.6877196909958796 0.0914650500530545 1.0 0.4800458677943752 80 P46108,Q16512,Q6SZW1,Q02750,Q96G23,Q14012,Q9UQB8,Q96PU5,P53990,P46109,P49841,P46934,P46821,Q96HC4,Q9UIW2,Q86X55,P07196,Q9P265,Q8N0X7 19 +Viral transcription 0.5162276034704657 1.6841091466602516 0.0921605770030327 1.0 0.4829272842639042 15 P19474,Q9H1E3 2 +Positive regulation by host of viral transcription 0.6480670519995022 1.683114168044738 0.0923529922654586 1.0 0.4831674008046854 7 Q9H1E3 1 +Negative regulation of cellular senescence 0.7387829062267763 1.6818296439226694 0.0926018786515858 1.0 0.4834586871399371 5 P67809 1 +Regulation of synapse structure or activity 0.3893562082447057 1.6808341067323582 0.0927951418083128 1.0 0.4834586871399371 37 Q16539,Q9NUL3,Q96HC4,Q04637,P43034,Q14203,Q14012,P07437,Q9Y4F1,Q9UQB8,P46934,P63104,Q00535 13 +Negative regulation of immune response 0.4310559115512831 1.679724943825211 0.0930108442711863 1.0 0.4834586871399371 28 Q16539,P28070,P04083,P19474 4 +Microtubule organizing center organization 0.3649108193518031 1.6792020490935469 0.0931126727702089 1.0 0.4834586871399371 49 Q9H6D7,O75351,P24941,Q14203,Q96CS2,Q9Y496,Q9NZZ3,Q15004,Q9H6U6,P41208,Q12873,Q8IWJ2,O43379,Q9UHD1,Q9HD42,P43034,O75122,O14965,Q6UVJ0,Q7Z460,O94927,P06493 22 +Regulation of wound healing spreading of epidermal cells 0.7740426775796667 1.6791589652710577 0.0931210669000912 1.0 0.4834586871399371 4 O75122,Q96AC1,Q7Z460 3 +Peptidyl lysine hydroxylation 0.6075058358638883 1.6790667768019991 0.0931390302522174 1.0 0.4834586871399371 8 Q92791,Q96AY3 2 +Regulation of wnt signaling pathway 0.3624733453290867 1.6777667882626155 0.0933926352817517 1.0 0.4840695152242167 51 Q16539,Q96AQ6,Q96K76,P52294,P30153,P98170,P49841,Q9H4A3,Q99471,Q6DKJ4,P40818,O60493,Q9HCK8,Q13283,Q13043,Q13526 16 +Response to oxidative stress 0.3288310982190741 1.6770390576994365 0.0935348444910872 1.0 0.4840695152242167 103 P00374,O43813,O75874,Q99720,P04083,Q15392,P04792,P28074,O75306 9 +Negative regulation of muscle tissue development 0.8904469763365537 1.6743524943080812 0.0940613433321506 1.0 0.4840695152242167 2 P16989 1 +Negative regulation of muscle organ development 0.8904469763365537 1.6743524943080812 0.0940613433321506 1.0 0.4840695152242167 2 P16989 1 +Regulation of actomyosin structure organization 0.4658262268579683 1.6723573613483145 0.0944538747432408 1.0 0.4849220734481649 23 Q7Z460,Q13177,Q96AC1,P07737,P35080,O75122,P16949,Q16512,O95429,O60504 10 +Negative regulation of ion transmembrane transport 0.4819107024458974 1.6712911908742438 0.0946641755751676 1.0 0.4853479785710328 20 P62942,P0DP25,P28161,Q12955,P46934,Q96PU5 6 +Late endosome to lysosome transport 0.6052285009153064 1.6674055620667367 0.095433788639943 1.0 0.487527294415399 8 Q9HD42 1 +Regulation of steroid metabolic process 0.4941513855900001 1.658767962462226 0.0971625584585369 1.0 0.4901127154643884 17 P34913 1 +Trna processing 0.3649780096670139 1.6587064582182829 0.0971749573895564 1.0 0.4901127154643884 47 Q9UI30,P49591,Q96SZ6,Q7Z4G4,Q9NXH9,Q8WWH5,Q9NX74,Q9UBP6,Q9UJA5,Q9NXG2,Q9H9T3,Q969Y2,P05455 13 +Axon development 0.3368628436058467 1.6558784825852642 0.0977464299528225 1.0 0.4914150635938324 85 P00374,Q12955,Q06124,P16949,Q16512,Q02750,Q9BVA1,Q96G23,Q9UQB8,P78559,Q16555,Q13740,P08238,P53990,P49841,P83731,Q13177,Q00535,P46821,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q8N0X7 25 +Interstrand cross link repair 0.6419787723854474 1.6536961293801549 0.0981892694979296 1.0 0.4925903078617595 7 Q9H1E3 1 +Regulation of macrophage chemotaxis 0.7661799097030108 1.6462180484540467 0.0997188746955095 1.0 0.4972366278311641 4 P30046 1 +Regulation of macrophage migration 0.7661799097030108 1.6462180484540467 0.0997188746955095 1.0 0.4972366278311641 4 P30046 1 +N terminal protein amino acid acetylation 0.6800885031306618 1.6443685067515748 0.1001001062957089 1.0 0.4983836108015964 6 P41227,Q86UY6,Q9BXJ9,Q5VZE5 4 +Female meiosis i 0.765460936725571 1.6432026472897725 0.1003410123548964 1.0 0.4988712262102136 4 O95067,Q15645 2 +Regulation of rna binding 0.5812740003588779 1.6418603555455102 0.1006189474449135 1.0 0.4988712262102136 9 Q9H1E3 1 +Microtubule polymerization 0.3901275899045063 1.638129094938287 0.1013947667959356 1.0 0.5002951367655746 34 O75122,P46821,Q15691,O43670,P36405,Q8IWC1,P23396,P23258,Q14203,Q13526,Q02790,P16949,Q16512,Q7Z460,P04350 15 +Ribonucleoside monophosphate biosynthetic process 0.4658677133704222 1.6333415722307347 0.1023971780026542 1.0 0.5042036163408321 22 P11172,Q9BZX2,P22102,P55263,Q06203,P00492,P30520,P22234,P07741,P31939,Q01433,P11908,P49915,P60891 14 +Regulation of ubiquitin protein transferase activity 0.4536683605519153 1.632598313209901 0.1025535062377032 1.0 0.5042036163408321 24 P62081,Q99497,P62841,O60566,Q16763,Q8TDB6,P63208,Q9UL15,P15880,P68036,Q13526,P46777,Q96GG9 13 +Regulation of potassium ion transport 0.5073205315890139 1.6293490028559496 0.1032391580215119 1.0 0.5063634893436063 15 Q12955,P46934,O95747,Q96PU5 4 +Negative regulation of immune system process 0.355023113252267 1.6254952829973652 0.1040570681062063 1.0 0.5090430711220965 53 P09429,Q16539,P19474,Q00534,O15347,P04083,Q9Y3Z3,Q7Z739,P28070,P51452,P25786,Q96J02,P46108,Q16512,P30046 15 +Neuron projection organization 0.4526636489100918 1.6253201229595209 0.1040943658787296 1.0 0.5090430711220965 24 Q13614,P49841,Q96HC4,Q14203,Q9UQB8,P78559,O60678,Q00535 8 +Positive regulation of interleukin 8 production 0.596554480695052 1.6228968707535785 0.1046114526243731 1.0 0.5095348633530613 8 P09429,Q13546,O95999 3 +Inflammatory cell apoptotic process 0.724971749277989 1.6220448717585547 0.1047937406838017 1.0 0.5095348633530613 5 P04083 1 +Positive regulation of protein export from nucleus 0.5451688157588367 1.6215764162137951 0.1048940757240635 1.0 0.5095348633530613 12 Q92688,Q14012,O95817,Q9C0E2 4 +Energy homeostasis 0.5667501464676087 1.6212255912544595 0.1049692662663801 1.0 0.5095348633530613 10 Q96E52 1 +Positive regulation of ubiquitin protein transferase activity 0.577084621582709 1.619635082005313 0.1053106889008728 1.0 0.5100720508703552 9 Q16763,P15880,P68036,Q13526,Q96GG9 5 +Myelin assembly 0.6346858807977543 1.6183756336396204 0.1055816698931573 1.0 0.5110090807163679 7 Q13614,Q9UPY3,Q9Y2J2 3 +Nucleobase containing small molecule biosynthetic process 0.6740433572440285 1.616670459166945 0.1059494337926687 1.0 0.511287457951151 6 P00491,P07741,Q13126,P23919 4 +Glycosyl compound biosynthetic process 0.6740433572440285 1.616670459166945 0.1059494337926687 1.0 0.511287457951151 6 P00491,P07741,Q13126,P23919 4 +Fatty acid transport 0.4825933248023826 1.6124084538460794 0.1068730864566829 1.0 0.5132874606196267 18 O43772 1 +Synapse organization 0.3326737813083529 1.6118857770034851 0.1069867977687146 1.0 0.5132874606196267 71 Q12955,Q14203,P35080,Q13526,O60678,Q16539,P07737,Q9Y4F1,Q14012,Q9UQB8,P07437,P20810,P46109,P46934,Q00535,P46821,Q13614,Q96HC4,P43034,P07196 20 +Cellular response to heat 0.3898803602270868 1.607848611990941 0.1078683387854593 1.0 0.5157925267373643 32 P08238,Q9UER7,Q99543,P42345,P49841,P25685,Q99615,O95817,Q13535,Q9UHD1,P17612,P51617,O75190,P07900 14 +Regulation of calcium ion transmembrane transporter activity 0.4862010711020741 1.6075080006907774 0.1079429757458103 1.0 0.5157925267373643 17 P42858,P62942,P27695,P28161,P78417,P17612,P62258,P0DP25,P30626,Q00535 10 +Response to growth factor 0.3061197578794184 1.6070630751831814 0.1080405322879871 1.0 0.5157925267373643 119 P62942,P98170,Q13526,Q96B36,P46108,Q8WUH2,Q16539,P04083,Q96AC1,Q53EL6,Q9UNH7,Q9UQB8,P46109,P04792,O14737,P04150,P46934,O43237,P49427,P51452,Q8N0X7 21 +Positive regulation of oxidoreductase activity 0.5639605159262324 1.606113213004097 0.1082490372571449 1.0 0.5158729747310256 10 P00374 1 +Early endosome to golgi transport 0.6712905641115421 1.6040407334714109 0.1087050742339634 1.0 0.5162286695497341 6 Q13596,O15260 2 +Regulation of monooxygenase activity 0.5527931194018634 1.6035465643408495 0.1088140373518946 1.0 0.5162286695497341 11 P00374 1 +Positive regulation of organ growth 0.6710404542426829 1.602892729029603 0.1089583392413522 1.0 0.5162286695497341 6 Q16539 1 +Negative regulation of leukocyte cell cell adhesion 0.5161884574985154 1.6027461237975045 0.1089907158779606 1.0 0.5162286695497341 14 P09429,P04083,Q96J02,P51452 4 +Positive regulation of interleukin 2 production 0.6696269047702115 1.596402963636432 0.11039885490311 1.0 0.5188597796415683 6 P23396,P04083 2 +Negative regulation of transport 0.3323161850555349 1.5959073281057483 0.1105094851882868 1.0 0.5188597796415683 84 Q99497,P62942,O75351,Q12955,Q06124,O95429,Q9P2B4,P09429,Q9H4A3,P04083,Q9UNF0,Q96PU5,Q16850,O95817,Q99439,Q9UHD1,Q9UKS6,O60343,Q9NT62,P46934,Q00535,Q13614,P46821,P28161,O95747,P0DP25 26 +Positive regulation of developmental growth 0.4046478700555967 1.593363156795174 0.1110787459139368 1.0 0.5204201087879685 30 Q16539,P46821,P53990,P16989,P43034,Q6IBS0,Q96PU5 7 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.7527896175827447 1.5899737035027768 0.111840732614568 1.0 0.5217651163448214 4 Q9UN37 1 +Endosomal vesicle fusion 0.8850887244208172 1.587538526194792 0.1123907285439105 1.0 0.522482145670986 3 Q8WUH2 1 +Regulation of cellular response to stress 0.296682702877024 1.5857373743828227 0.1127988972134044 1.0 0.5240100989645962 174 P00374,Q99497,Q99504,P98170,P51114,Q99543,Q92995,P36507,P25685,O95251,P15311,P15927,Q96J02,P67809,P55145,P09429,Q96K76,Q00534,Q96T76,O43813,Q02750,Q9NYB0,Q9NY27,Q13535,P31689,Q53EL6,Q96G23,Q9UNS1,O96028,O95881,P14174,Q96KB5,P23396,P78318,P16989,Q96FW1,P49841,Q99615,P04792,O75832,Q9UHD1,Q13546,Q96Q15,Q9UNS2,Q7Z4V5,P43034,P51452,O94966,Q92905,Q9NQ88,Q04323 51 +Protein modification by small protein removal 0.3467536411419032 1.579528464824721 0.1142148927898139 1.0 0.5275850708564794 56 Q15018,P19474,Q96K76,Q99497,Q01804,Q96FW1,Q9UNS2,Q92995,Q96RU2,Q7L5N1,P40818,P61201,Q9NWV8,Q96J02,O94966,Q9UBW8,Q92905,Q04323 18 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3850513555333066 1.5787430013067 0.1143950172155854 1.0 0.5275850708564794 33 P09429,Q9UQ84,P04083,O96028,Q9NUQ9,P13051,Q16512 7 +Cellular component maintenance 0.5374554262144995 1.5779987385405174 0.114565899604047 1.0 0.5275850708564794 12 Q96AC1,Q13614,Q9C0E8 3 +Positive regulation of protein localization to early endosome 0.7146198830409372 1.5770897555422507 0.114774874089041 1.0 0.5275850708564794 5 O75116,P26038,Q8TDB6,P15311 4 +Regulation of protein localization to endosome 0.7146198830409372 1.5770897555422507 0.114774874089041 1.0 0.5275850708564794 5 O75116,P26038,Q8TDB6,P15311 4 +Cell death in response to oxidative stress 0.439354943213251 1.576869466773876 0.1148255634260233 1.0 0.5275850708564794 25 O43813,Q99720 2 +Positive regulation of erythrocyte differentiation 0.5246195042262336 1.5765055829029904 0.1149093331506385 1.0 0.5275850708564794 13 Q16539,Q15648,O95251,P42224,Q96KR6,P78527,Q99873 7 +N acetylglucosamine metabolic process 0.7495122451824954 1.576181483126357 0.1149839846499083 1.0 0.5275850708564794 4 O60502,Q9UJ70 2 +Negative regulation of dephosphorylation 0.4852875841603741 1.575370848770304 0.1151708691019135 1.0 0.5275850708564794 16 Q15257,P17931,P62942,P49841,O43768,O75116,Q9UHD1,P62258,O95429,P31946 10 +Synaptic vesicle recycling via endosome 0.8817867994417776 1.57470262573801 0.1153251014642431 1.0 0.5275850708564794 3 O00203 1 +Dna geometric change 0.3446269631771118 1.5717001532262855 0.1160201066410824 1.0 0.528798314012547 57 Q9Y248,P49736,P40938,P09429,Q9H4L7,P04083,Q8N3C0,P13010,O14646,P33991,P46063,Q12873,Q86WJ1,Q04837,Q9HCK8,O15347,Q9BRT9,P25205,P38935,Q13283,P13984,Q9Y620 22 +Negative regulation of toll like receptor signaling pathway 0.7132123303103568 1.570968285320691 0.1161900156592694 1.0 0.528798314012547 5 Q01804 1 +Pyrimidine nucleoside triphosphate biosynthetic process 0.557464927314744 1.5708650626271292 0.1162139953625871 1.0 0.528798314012547 10 P15531,P22392,Q9NRF8,P17812 4 +Antigen processing and presentation via mhc class ib 0.8805810153524865 1.570013929737181 0.1164118706280588 1.0 0.528798314012547 3 O00203 1 +Pyrimidine nucleotide catabolic process 0.8797425197241054 1.5667530295656529 0.1171724302348153 1.0 0.5296687288617519 3 Q9H773 1 +Cellular modified amino acid metabolic process 0.3440400071177157 1.5652813178697502 0.1175169616598617 1.0 0.529872959320998 57 P00374,O75874,P28161,P21266,Q04760 5 +Negative regulation of inflammatory response 0.4968555984309205 1.5647538848473828 0.1176406284167317 1.0 0.529872959320998 15 Q96KB5,Q16539,P28070 3 +Protein kinase a signaling 0.5666545356780869 1.5641520923194856 0.1177818548963687 1.0 0.5299781484483703 9 Q02952,O00170,P15311,P17612,P14174 5 +Snrna transcription by rna polymerase ii 0.7109255723540777 1.561018812890254 0.1185193121053016 1.0 0.5305267010587205 5 P55199,Q4G0J3 2 +Snrna transcription 0.7109255723540777 1.561018812890254 0.1185193121053016 1.0 0.5305267010587205 5 P55199,Q4G0J3 2 +Protein hydroxylation 0.4829887015467283 1.5606981044966255 0.118594998723347 1.0 0.5305267010587205 16 Q92791,Q96AY3 2 +Negative regulation of b cell activation 0.7103855925426587 1.558668641234806 0.1190748275434181 1.0 0.5305267010587205 5 O15347 1 +Pyrimidine ribonucleoside triphosphate metabolic process 0.5840215049341483 1.558341628655445 0.1191522857224294 1.0 0.5305267010587205 8 P15531,P22392,P17812 3 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.5840215049341483 1.558341628655445 0.1191522857224294 1.0 0.5305267010587205 8 P15531,P22392,P17812 3 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2748471922097234 1.55649271401479 0.1195909738709466 1.0 0.5308711782877308 140 Q93034,P62191,Q99497,O95155,P51665,O14980,Q9UNN5,Q8WW12,Q6NTF9,Q8IYU2,Q9H1I8,Q13200,P43686,P24941,Q15008,Q96J02,Q99460,Q86UK7,Q15370,P54578,Q9Y5K6,P48556,Q5VYK3,P48729,Q8IUR7,P62333,Q16763,Q8N3C0,P63208,Q9NXV2,P78559,Q96KB5,P17980,Q96PU5,P08238,P62195,P25787,P49841,O75832,Q9NZJ0,Q7Z6Z7,P46934,P49427,O94888,Q9UBV2,P54727,P10398,Q9UL15,Q13309,P54725,O94966,O14965,Q9Y5A7,Q04323,Q9UBU6 55 +Cellular component assembly involved in morphogenesis 0.4598081042360157 1.555104009598446 0.1199213001885493 1.0 0.5317181273070984 21 P18074,Q13614,Q16527,P43034,Q9UPY3,Q9Y2J2,O75122,Q13045,Q7Z460 9 +Cellular response to chemical stress 0.3290054022359266 1.5539690367975716 0.1201918025391408 1.0 0.5321050116440675 84 P00374,P16989,O43813,Q99720,P04083 5 +Regulation of ubiquitin dependent protein catabolic process 0.3334859951002955 1.5526880671023806 0.120497674502277 1.0 0.5327608232017659 63 P48729,P08238,Q99497,P62081,Q9H2J4,P49841,P54727,P10398,O75832,P24941,P54725,P78559,Q96KB5,Q15370,Q04323 15 +Developmental cell growth 0.3515654648307945 1.5526717453753494 0.1205015757575596 1.0 0.5327608232017659 50 P78344,P50570,O60271,Q16555,Q13740,Q96PU5,P08238,P53990,P49841,P18206,Q93008,P46940,Q00535,P46821,Q96HC4,P43034,Q9UIW2,Q14247,Q9P265,Q6IBS0,O14965,Q9UL25,Q8N0X7,P07900 24 +Oocyte construction 0.7434712080969417 1.5507341699392163 0.120965402242962 1.0 0.5340730080957715 4 Q8N2A8 1 +Spindle organization 0.3253386207968426 1.547514012256049 0.121739348266868 1.0 0.5357181467124127 94 Q15018,Q15691,P30153,O75351,Q9H6D7,P33981,P15311,Q9Y266,Q14203,P62826,P16949,Q96CS2,Q9NZZ3,Q15813,Q9HBM1,Q14674,P07437,P23396,O43670,Q12873,O43379,Q9BV86,Q9HD42,Q15257,Q15555,Q9P287,O95067,O75122,O14965,Q7Z460 30 +Phosphatidylethanolamine metabolic process 0.7069312641152596 1.543627462551836 0.1226786080936843 1.0 0.5379865470629724 5 P35790 1 +Negative regulation of response to wounding 0.5626917921280877 1.5430192082042142 0.1228261154929875 1.0 0.5379865470629724 9 P46108,Q96G23 2 +Dendritic spine morphogenesis 0.4798268332247231 1.5404967053745142 0.1234393252679577 1.0 0.5397556211497446 16 P61160,Q9NUL3,Q96HC4,P43034,P23528,Q12756,Q9UQB8,O60678,Q00535 9 +Positive regulation of t cell receptor signaling pathway 0.8583114227286042 1.5400115865273296 0.1235575291739934 1.0 0.5397556211497446 2 P23396 1 +Positive regulation of antigen receptor mediated signaling pathway 0.8583114227286042 1.5400115865273296 0.1235575291739934 1.0 0.5397556211497446 2 P23396 1 +Regulation of actin filament bundle assembly 0.4471265829381485 1.5394306820744643 0.1236991884020937 1.0 0.5400165893686104 23 Q7Z460,P42345,O75116,Q13177,Q96AC1,P07737,P35080,O75122,P16949,Q16512,O95429,O60504 12 +Cd4 positive alpha beta t cell differentiation 0.7405472041385017 1.5384061193753031 0.123949346960571 1.0 0.540323928026712 4 P04083 1 +T cell differentiation involved in immune response 0.7405472041385017 1.5384061193753031 0.123949346960571 1.0 0.540323928026712 4 P04083 1 +Protein k63 linked ubiquitination 0.5049776984701098 1.535511076644433 0.1246583383680222 1.0 0.5416891476863939 14 P19474,P46934,Q96FW1 3 +Positive regulation of pathway restricted smad protein phosphorylation 0.7398361337971792 1.5354071022901763 0.1246838602350526 1.0 0.5416891476863939 4 P33981 1 +Glucosamine containing compound metabolic process 0.7049045200181385 1.5347970716843078 0.1248336823348841 1.0 0.5416891476863939 5 O60502,Q9UJ70 2 +Columnar cuboidal epithelial cell differentiation 0.5296819916411868 1.5339646481436635 0.1250383500473817 1.0 0.5419150581935177 12 P46821,Q00534,P49841,Q9P287,Q9NQ88 5 +Sterol biosynthetic process 0.4334765277024016 1.5332250048419631 0.1252204253182007 1.0 0.5423475976988039 25 Q15125,Q9UBM7,Q16850 3 +Muscle cell migration 0.4916996792978638 1.532835534779838 0.1253163827574341 1.0 0.5424068254346724 15 Q9UIW2,P04083 2 +Imp biosynthetic process 0.5603033264942188 1.5302684627633312 0.1259502911733323 1.0 0.543880151382938 9 P22102,Q06203,P00492,P07741,P31939,Q01433 6 +Response to x ray 0.5166618064535367 1.530120920241805 0.1259868008437115 1.0 0.543880151382938 13 Q9H1E3 1 +Production of sirna involved in rna interference 0.7382705091841469 1.5288025156824965 0.1263134085541166 1.0 0.544894183460979 4 Q9UPY3,Q15631 2 +Regulation of protein dephosphorylation 0.3791518301482312 1.52651538574617 0.1268815617030589 1.0 0.5463516022373701 33 Q8IV63,P17931,P62942,P08238,Q15257,P49841,O43768,P0DP25,Q5H9R7,Q14738,Q13526,Q15435,P31946,P42858 14 +Negative regulation of protein modification by small protein conjugation or removal 0.360086219637071 1.5262185561004995 0.126955443684738 1.0 0.5463516022373701 43 P19474,P62081,Q99497,P62841,Q96FW1,P23396,Q6DKJ4,Q13107,P31689,Q9UHD1,O60678,Q04323,Q00535 13 +Cellular glucan metabolic process 0.4775827597522418 1.526145215138081 0.1269737036753111 1.0 0.5463516022373701 16 P13807,P06737,P31751,P49841,P08237,P11216,P35573,P46976,Q16851 9 +Dendrite extension 0.6155590499276229 1.5253521763901323 0.1271712802489375 1.0 0.5468448006529656 7 Q96PU5 1 +Regulation of cation channel activity 0.4553693781007626 1.5244968153386202 0.127384651794397 1.0 0.5472565707452015 21 P62942,P27695,Q00535,P28161,Q12955,P17612,P0DP25,P42858 8 +Stress granule assembly 0.4647404958265983 1.5239704456243328 0.1275160941542217 1.0 0.5472565707452015 19 Q8WWM7,Q9Y5A9,Q14157,Q7Z739,Q14011,P62266,Q13131,Q13283,Q9UN86,Q14204 10 +Positive regulation of myeloid cell apoptotic process 0.8685980017858606 1.5233830826267842 0.1276628919716986 1.0 0.5475301131278059 3 P04083 1 +Positive regulation of actin filament bundle assembly 0.5028640702325142 1.522805617174813 0.1278073442333138 1.0 0.5477932465448667 14 Q96AC1,P07737,P35080,Q16512,O60504 5 +Positive regulation of cell population proliferation 0.2715440988972197 1.5202759007552056 0.1284416482402677 1.0 0.5490838814525583 138 Q9H2J4,P33981,O00716,O95251,P24941,Q9UBL3,Q16512,O75794,P09429,Q16539,Q00534,P55209,P04083,Q96AC1,P14174,P23396,Q86Y37,P15531,Q96AQ6,P46109,O43379,Q9NQG5,P22392,P43490,P00491,P49006,O60884,Q86X55,O95747 29 +Cellular amino acid biosynthetic process 0.3954886285536601 1.517071707372169 0.1292485805676628 1.0 0.5499065117947336 30 P00374 1 +Positive regulation of phosphoprotein phosphatase activity 0.6522145794175955 1.5162544046503934 0.1294550360537725 1.0 0.5499065117947336 6 P0DP25,P08238,Q15257,Q8IV63 4 +Cell junction disassembly 0.7005313122650648 1.5157303785125955 0.1295875428267476 1.0 0.5499065117947336 5 P51452,Q15555,Q00535 3 +Negative regulation of ion transport 0.4437104444665272 1.51504895153767 0.1297600079179159 1.0 0.5499065117947336 23 P62942,P0DP25,P28161,Q12955,O95747,P46934,Q96PU5 7 +Regulation of t cell differentiation 0.5367923045324714 1.5147873592165002 0.1298262626843285 1.0 0.5499065117947336 11 P09429,P00491,P04083,O00203,O14617 5 +Positive regulation of epithelial cell migration 0.3761660362488075 1.513557455747048 0.1301381184072143 1.0 0.5502697091342892 34 P09429,Q16539,Q15555,P04083,P04792,P07737,O75122 7 +T cell activation involved in immune response 0.6129062541609684 1.512409689092561 0.1304296715702044 1.0 0.5507811847100866 7 P09429,P42345,P17931,P04083 4 +Retrograde axonal transport 0.536138398653784 1.5111503331193854 0.1307501532355086 1.0 0.5507813370391067 11 P27695,P43034,P07196,Q12756,Q9NZ32,P78559 6 +Regulation of proteolysis 0.2913263058517417 1.5093344373296709 0.1312133384314138 1.0 0.5519836164262155 172 P62191,Q99497,O14980,P98170,Q9H2J4,O43847,Q92995,P30086,P61201,P24941,Q96J02,Q15370,Q9GZU8,P09429,P19474,Q96K76,P48729,P62333,P17612,Q96KB5,P30740,Q92688,P78318,P17980,P23396,P25788,P78559,P08238,P04080,P20810,P53990,P06744,P62195,P49841,Q13177,Q9C0C9,O14737,O75832,P61289,Q9GZP4,Q9UKS6,Q9UL46,O95831,Q00535,Q01804,P62081,Q9UMY4,O95999,Q15392,P54727,Q9Y3D6,P10398,P54725,P19784,O94966,O14965,O75190,Q04323 58 +Zymogen activation 0.5743929038096329 1.5085668688353806 0.1314095062207072 1.0 0.5524562914584835 8 Q96E52 1 +Inositol phosphate metabolic process 0.6502853465132643 1.507352327385705 0.1317203714673527 1.0 0.5533880969107564 6 Q01968,Q13614 2 +Protein localization to microtubule end 0.8498393222319669 1.5045352885462846 0.1324435942025292 1.0 0.5538679460881094 2 Q15555 1 +Peptidyl serine modification 0.3248254968933494 1.5045099907170345 0.1324501028589795 1.0 0.5538679460881094 75 Q8IV63,Q99497,P42345,P36507,P33981,Q13043,P24941,P35080,Q16512,O95429,Q16539,P48729,Q9H4A3,Q9NYB0,Q13535,Q14012,P17612,P14174,P08238,P31751,P49841,Q13177,Q04637,Q9BV86,Q13546,Q99986,Q00535,Q96Q15,P41227,P10398,P19784,O14965,Q7Z460,P07900 34 +Formation of translation preinitiation complex 0.5554311956217016 1.5042290187266505 0.1325224083326577 1.0 0.5538679460881094 9 P23588,Q15056 2 +Protein k48 linked deubiquitination 0.5122128294429289 1.5041363611312506 0.132546259586652 1.0 0.5538679460881094 13 Q01804,Q96FW1,Q92995,P40818,O94966,Q04323 6 +Tolerance induction 0.8633170309900334 1.5028151635697242 0.1328867145678045 1.0 0.5544235585006123 3 Q96J02 1 +Microtubule anchoring at centrosome 0.6970085720893157 1.5003593563041957 0.1335213416944596 1.0 0.5550976270434447 5 P49841,Q86VS8,Q14203 3 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.4990417421776915 1.4998071399560962 0.1336643673025859 1.0 0.5550976270434447 14 P09429,O95999,P04792,Q06124,P14174,P30046 6 +Protein localization to endosome 0.534072954941323 1.4996577395635395 0.1337030827954888 1.0 0.5550976270434447 11 P26038,O75116,P62330,P15311,Q9UNF0,Q8TDB6 6 +Nucleobase biosynthetic process 0.4695465253643571 1.499605848428485 0.1337165318506601 1.0 0.5550976270434447 17 P49915,P11172,P42345,Q06203,Q9NRF8,P17812,P60891 7 +Glucan biosynthetic process 0.5235728545950833 1.4992830281011953 0.133800223378117 1.0 0.5550976270434447 12 P13807,P31751,P49841,P35573,P46976 5 +Purine containing compound salvage 0.6100621380489722 1.4985237970450829 0.133997214588424 1.0 0.555224022510075 7 P00491,P55263,Q13126,P07741,Q01433 5 +Regulation of extent of cell growth 0.4348680724873486 1.4959524847434615 0.1346660377113471 1.0 0.5572620970453234 24 P46821,P53990,P49841,P43034,Q9P265,Q6IBS0,Q8N0X7,Q00535 8 +Leukocyte homeostasis 0.4982367006412501 1.4949598778508668 0.1349249136149302 1.0 0.5573177955524917 14 P09429,O95999,P04083,O95067,Q16512 5 +Regulation of developmental growth 0.3401701809829003 1.493930544066559 0.1351937740773965 1.0 0.5573177955524917 55 Q16539,P46821,P53990,P16989,P49841,Q00535,P43034,P15311,O60271,Q13043,Q9P265,Q6IBS0,Q8N0X7,Q96PU5 14 +Developmental growth involved in morphogenesis 0.3467763096817612 1.4925603718944795 0.1355523030341092 1.0 0.5573177955524917 49 Q15648,O60271,Q16555,Q13740,Q96PU5,P08238,P53990,P49841,Q93008,Q13263,P46940,Q00535,P46821,P43034,Q9UIW2,Q9P265,Q6IBS0,O14965,Q9UL25,Q8N0X7,P07900 21 +Negative regulation of cell activation 0.4456841007719818 1.4920020641962886 0.1356986042014778 1.0 0.5573365725209607 22 O15347,P04083,P51452,Q96J02,Q16512 5 +Organophosphate catabolic process 0.3668345368267107 1.4910649743062134 0.1359444370393696 1.0 0.5574749285528359 38 Q9H773,Q6SZW1,Q13614,O75874,Q9BQG2,Q9UKK9 6 +Ribonucleoside monophosphate metabolic process 0.3765563775232566 1.4909066853837711 0.1359859959212621 1.0 0.5574749285528359 32 P11172,P00491,Q9BZX2,P22102,Q9UDY2,P55263,Q06203,P00492,P30520,P22234,P07741,P31939,Q01433,Q9P2T1,P11908,P49915,P60891 17 +Regulation of neuron projection regeneration 0.729154358216115 1.4903100980271131 0.1361427185671346 1.0 0.557534737618303 4 Q96G23 1 +Negative regulation of cell adhesion mediated by integrin 0.8454572012854236 1.4861808696595395 0.1372312862219544 1.0 0.557534737618303 2 Q9H4A3 1 +Regulation of t cell migration 0.6069911319713903 1.4835189867528755 0.1379365757237798 1.0 0.557534737618303 7 O95747,P46108,P46109 3 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.8445807770961137 1.482509748293062 0.1382047116974711 1.0 0.557534737618303 2 Q9UNN5 1 +Blastocyst growth 0.540985780726543 1.4811009955318113 0.13857966263777 1.0 0.557534737618303 10 Q92541,Q9BRT9 2 +Positive regulation of blood vessel endothelial cell migration 0.4832056577967608 1.4801324029887066 0.1388379156624641 1.0 0.557534737618303 15 P04792,Q16539,P04083 3 +Positive regulation of sodium ion transport 0.5686747020636556 1.4789403181959024 0.139156266416998 1.0 0.557534737618303 8 Q9H4A3,O43865,Q12955 3 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.843704352906814 1.4788385691669057 0.1391834648928207 1.0 0.557534737618303 2 P62081 1 +Protein heterooligomerization 0.5499634716313684 1.474961396348556 0.1402229222870266 1.0 0.5590985152294174 9 P31153,P31350,Q9Y285,Q8N684,Q9NSD9,O43809,P23921 7 +Amyloid fibril formation 0.539578065699772 1.4734125711907269 0.1406398225821923 1.0 0.5590985152294174 10 Q9NQP4,O15212,P62942,Q9UHV9,Q99471,Q13546 6 +Positive regulation of phosphatase activity 0.6048572646501904 1.4730864298457274 0.1407277320463218 1.0 0.5590985152294174 7 P08238,Q15257,P0DP25,Q8IV63 4 +Axo dendritic transport 0.3745088221629631 1.472890452525034 0.1407805768886654 1.0 0.5590985152294174 32 Q9Y496,Q9NUL3,P27695,P04792,O00203,P43034,Q12756,Q14203,Q9NZ32,P07196,P78559,Q9UL25,O14617,Q92572 14 +Negative regulation of ubiquitin protein ligase activity 0.5495219006527068 1.4725957830407852 0.1408600625656688 1.0 0.5590985152294174 9 P62081 1 +Regulation of protein kinase a signaling 0.7249485256528351 1.4725321939869616 0.1408772199326551 1.0 0.5590985152294174 4 P14174,O00170 2 +Detoxification of nitrogen compound 0.7246731135591371 1.4713676525825483 0.1411917164709819 1.0 0.5593364152504284 4 P28161 1 +Intra golgi vesicle mediated transport 0.4566879193387715 1.4700679293105112 0.1415433571908093 1.0 0.5593847286720509 19 P35606,P83436,P53618,P53621,Q9UBF2,P61923,O43617,Q9Y678,Q9UP83,Q9H9E3,P60520 11 +Transcription initiation from rna polymerase ii promoter 0.4182816741774305 1.4689627019331375 0.1418429060197443 1.0 0.5593847286720509 26 P09429,O60244,P62333,Q14241,Q15648,O00716,Q86VP6,P29083,P13984,Q15370,O75448 11 +Response to muramyl dipeptide 0.689814954975358 1.4689394062702992 0.1418492250594207 1.0 0.5593847286720509 5 Q16539 1 +Negative regulation of cellular protein catabolic process 0.3820053748480581 1.4689222596126943 0.1418538762955297 1.0 0.5593847286720509 31 P08238,P62081,Q99497,Q9H2J4,Q9UL15,O15372,O00560,P19784,O94966,P78559,Q96KB5,P60520,P54578,Q04323,Q9GZU8 15 +Positive regulation of sodium ion transmembrane transporter activity 0.6416663893990033 1.4675344611528196 0.1422307218409622 1.0 0.5594182090546674 6 Q9UHD1,Q9H4A3,P35754,Q12955 4 +Positive regulation of actin cytoskeleton reorganization 0.6886738786179304 1.4639518265221634 0.1432071112765993 1.0 0.5625871737397753 5 Q9UQB8,Q00535 2 +Negative regulation of nf kappab transcription factor activity 0.459620124118765 1.461245895315245 0.1439479720125236 1.0 0.5644884185047923 18 P19474,P42771,O75832,Q96J02,Q9UHD1,P51617,Q9UNN5 7 +Rna guanine n7 methylation 0.8524431585598988 1.4604389430901092 0.144169476501867 1.0 0.5645828447744422 3 Q9UBP6 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.5167166685890036 1.4602896522506796 0.1442104847431462 1.0 0.5645828447744422 12 P30154,O95999,P30153,Q13043,Q13546,Q9UNN5 6 +Polysaccharide biosynthetic process 0.4633453385612647 1.4592746883502306 0.1444895191310382 1.0 0.5652670089684297 17 P13807,O43505,P31751,P49841,P35573,Q93063,P46976 7 +Positive regulation of ryanodine sensitive calcium release channel activity 0.8518467500364754 1.4581139070813296 0.1448091487065141 1.0 0.5658458258881692 3 P28161 1 +Stress fiber assembly 0.4167435155568527 1.4572528058594916 0.1450466089844928 1.0 0.5664379421953654 26 Q7Z460,Q13177,Q96AC1,P07737,P35080,O75122,P16949,Q16512,O95429,O60504 10 +Response to hydrogen peroxide 0.3879187778204598 1.4538505248079132 0.1459877521264172 1.0 0.5681887402675178 30 P46108,P23396,P04083,Q99720 4 +Regulation of canonical wnt signaling pathway 0.3609231483384721 1.4534646825088076 0.1460947787020869 1.0 0.5681887402675178 39 Q16539,Q96K76,P52294,P98170,P49841,Q9H4A3,Q99471,P40818,Q9HCK8,Q13283,Q13043,Q13526 12 +Negative regulation of supramolecular fiber organization 0.3409647504937588 1.4530855782514216 0.1461999947257011 1.0 0.5682490361036685 51 Q9NQP4,Q15691,P47755,P35080,P16949,Q9UHV9,Q99471,P07737,O15212,Q13177,Q9BPX3,P60983,P35241,Q9NUQ9,Q02790,Q13045,P46821,P61758,Q6IBS0,O75122,Q7Z460,P04350 22 +Peptidyl serine dephosphorylation 0.6859316782077096 1.451962022974572 0.1465121651595662 1.0 0.5688228296063884 5 P53041,P63151,P30153 3 +Regulation of dendritic spine morphogenesis 0.502515291156872 1.4473828073474837 0.1477897382781705 1.0 0.5711270596642908 13 Q9NUL3,Q96HC4,P43034,P23528,Q12756,Q9UQB8,Q00535 7 +Negative regulation of jun kinase activity 0.8361086765994857 1.447020672590804 0.1478911337682695 1.0 0.5711270596642908 2 Q53EL6 1 +Modification of synaptic structure 0.562459415550248 1.4466874884314558 0.1479844702134773 1.0 0.5711270596642908 8 Q9UQB8,P07737 2 +Canonical wnt signaling pathway 0.3582225677920852 1.4463207921110874 0.1480872465955391 1.0 0.5711270596642908 40 Q16539,Q96K76,P52294,P98170,P49841,Q9H4A3,Q99471,P40818,Q9HCK8,Q13283,Q13043,Q13526 12 +Negative regulation of alpha beta t cell activation 0.7184736038897003 1.445142324993604 0.1484179125486617 1.0 0.5711510840710621 4 P04083,Q96J02 2 +Cell cell signaling by wnt 0.3190608134826068 1.443318340575562 0.1489308155769686 1.0 0.5721769029320897 72 Q92541,P30153,P98170,O60493,Q9GZS3,Q13043,Q13526,Q16539,Q96K76,Q9H4A3,Q99471,Q96AC1,Q96AQ6,O43815,P49841,Q6DKJ4,P40818,Q9HCK8,P52294,Q13283 20 +Chaperone mediated protein folding 0.357871015676629 1.4429841905618097 0.1490249247854107 1.0 0.5721769029320897 40 Q9H2J4,P04792,P62942 3 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3787711801115653 1.4411872795258494 0.1495317810885077 1.0 0.5721769029320897 31 Q969T7,Q5TAX3,P67809 3 +Odontoblast differentiation 0.834355828220863 1.4396782253071805 0.1499584566351814 1.0 0.5721769029320897 2 P46821 1 +Regulation of dna primase activity 0.6830955335800313 1.439556070654874 0.1499930356768168 1.0 0.5721769029320897 5 Q9Y248,Q9BRT9 2 +Positive regulation of chemokine c x c motif ligand 2 production 0.8340636868244292 1.4384545034654708 0.1503051375826927 1.0 0.5721769029320897 2 P09429 1 +Chemokine c x c motif ligand 2 production 0.8340636868244292 1.4384545034654708 0.1503051375826927 1.0 0.5721769029320897 2 P09429 1 +Negative regulation of macrophage migration 0.8340636868244257 1.4384545034654566 0.1503051375826967 1.0 0.5721769029320897 2 P30046 1 +Negative regulation of macrophage chemotaxis 0.8340636868244257 1.4384545034654566 0.1503051375826967 1.0 0.5721769029320897 2 P30046 1 +Response to interleukin 4 0.5977179637214662 1.438145458593736 0.1503927867153871 1.0 0.5721769029320897 7 P08238,P49327,P12268,P39023,P11802,P49736 6 +Pyrimidine ribonucleotide biosynthetic process 0.5229587354904444 1.4377048136112365 0.1505178267334246 1.0 0.5721769029320897 11 P15531,P22392,Q9NRF8,P17812 4 +Pyrimidine ribonucleotide metabolic process 0.5229587354904444 1.4377048136112365 0.1505178267334246 1.0 0.5721769029320897 11 P15531,P22392,Q9NRF8,P17812 4 +Regulation of actin filament length 0.3431358231655148 1.4366716984111485 0.1508113003186437 1.0 0.5721769029320897 47 O15144,P47755,P42345,P35080,O95429,Q12792,Q9Y281,P07737,Q9UQB8,O15145,Q9BPX3,P35241,Q14019,Q9NUQ9,Q13045,P58546,P60981,Q9UEY8,P62330,Q14247,Q6IBS0,Q9UHB6 22 +Late endosome to vacuole transport 0.5226294368998216 1.4358666154187183 0.1510402997450552 1.0 0.5721769029320897 11 Q92783,Q9NZZ3,Q9HD42 3 +Neuron projection extension 0.3550998245964546 1.4357501338706973 0.151073453920937 1.0 0.5721769029320897 41 P78344,P50570,O60271,Q16555,Q13740,Q96PU5,P08238,P49841,P18206,Q93008,P46940,Q00535,P46821,P43034,Q9UIW2,Q14247,Q9P265,Q6IBS0,O14965,Q9UL25,P07900 21 +Caveolin mediated endocytosis 0.8460792629458802 1.435626883843838 0.151108540648668 1.0 0.5721769029320897 3 Q96PU5 1 +Cellular response to molecule of bacterial origin 0.3781197984202059 1.435598917206926 0.1511165030347039 1.0 0.5721769029320897 31 P09429,Q16539,O95999,Q9NZZ3,P14174,Q53EL6,Q9NUQ9,O43823 8 +Negative regulation of mrna catabolic process 0.4138030958042731 1.4348560063189788 0.1513281343835137 1.0 0.5725703950887857 26 Q16539,P67809,P16989 3 +Negative regulation of protein localization to membrane 0.5424187468414182 1.434504497766064 0.1514283464878962 1.0 0.5725703950887857 9 P41240,Q9ULT8,Q9HD26,Q9NQ48,Q13492,Q96CW1,O75608 7 +Regulation of meiotic cell cycle 0.5599055635618189 1.4334206732635095 0.1517376538932189 1.0 0.5728835134387739 8 P30307,Q15645,Q86U44,P33981 4 +Cellular nitrogen compound catabolic process 0.2881585606305827 1.4330988703568983 0.1518295842346617 1.0 0.5729024723954724 174 Q9H773,Q96C86,P51114,Q9BQ61,Q969T7,Q96HR8,P67809,Q9H814,Q16539,Q6SZW1,Q5TAX3,Q13126,Q9BQG2,Q14011,P16989,P05455,Q96Q15,Q9HCE1,Q9UKK9,P13051 20 +Developmental pigmentation 0.5593721295997905 1.430648592719495 0.1525309533732894 1.0 0.5742341774053251 8 Q9BXS5,Q92995,O14617 3 +Regulation of cyclase activity 0.6332110993083644 1.4284046347217347 0.1531754259330888 1.0 0.5760025144044049 6 Q16539 1 +Modification dependent macromolecule catabolic process 0.3063333826534232 1.4274302446480758 0.1534559182379538 1.0 0.5760714197178766 212 Q93034,Q9UN37,Q99497,O95155,P51665,O43242,Q9H2J4,O75351,Q92995,Q8WW12,Q6NTF9,Q9UNN5,Q9UNM6,Q9H1I8,Q13200,Q5T4S7,P24941,Q15008,Q96J02,Q99460,Q15370,P48556,Q9H9H4,P48729,Q96K76,P62333,Q5TAX3,Q9NZZ3,Q8N3C0,Q16763,P63208,Q9UHG3,Q9NXV2,P78559,Q96KB5,P17980,Q96PU5,Q86Y37,P08238,Q4G0X4,P62195,P25787,P49841,Q96RU2,P40818,Q13107,Q92783,P68036,O75832,Q15386,Q9NZJ0,Q7Z6Z7,P46934,Q8NBM8,Q8TDB6,Q9HD42,P49427,P62081,O94888,Q9UNS2,P54727,P10398,Q13309,P54725,O95260,O94966,O14965,Q9UBU6,Q04323,Q8IYU2 70 +Protein localization to cytoplasmic stress granule 0.5939191591256282 1.419532179425866 0.1557439220857028 1.0 0.5793814528154364 7 P67809,P05455 2 +Post chaperonin tubulin folding pathway 0.6782877589679281 1.4185141659798317 0.1560407058223414 1.0 0.5801098339592026 5 Q15813 1 +Amp metabolic process 0.4852383763546913 1.4165479988064338 0.1566151212950326 1.0 0.5806562877260153 14 P22102,P55263,Q06203,P00492,P30520,P07741,P31939,Q01433,P11908 9 +Regulation of protein modification by small protein conjugation or removal 0.3143956198459912 1.414845661727602 0.1571137527966275 1.0 0.581275569917313 96 Q9NVI1,Q99497,P62942,P98170,Q9UBE0,P15880,Q96J02,Q13526,O60678,P19474,P62841,P31689,P23396,P08238,Q96FW1,Q6DKJ4,Q13107,P68036,O75832,Q9UHD1,Q7Z6Z7,Q96GG9,Q00535,Q01804,P62081,O95999,Q96DY7,Q13309,Q9UBT2,Q04323 30 +Keratinocyte migration 0.6773393970345526 1.4143619240488925 0.1572556637093238 1.0 0.581275569917313 5 P42345,Q15555 2 +Regulation of keratinocyte migration 0.6773393970345526 1.4143619240488925 0.1572556637093238 1.0 0.581275569917313 5 P42345,Q15555 2 +Positive regulation of axonogenesis 0.4483800429441079 1.4143317136628224 0.1572645295517225 1.0 0.581275569917313 19 P46821,Q02750,P53990,Q9UIW2,P07196,Q6IBS0 6 +Imp metabolic process 0.5086226805700322 1.414172608945966 0.1573112282664572 1.0 0.581275569917313 12 P00491,P22102,Q06203,P00492,P30520,P07741,P31939,Q01433 8 +Phospholipid biosynthetic process 0.3227213679339946 1.4103192824686377 0.1584454273542648 1.0 0.5841736925830623 62 Q13614,P42356,O75874,Q96Q15,Q8NEB9,Q9NPH0,Q9HBU6,Q13907,Q8NCE2,P35790 10 +Dephosphorylation of rna polymerase ii c terminal domain 0.8261758691206605 1.4054177349843004 0.1598970960653105 1.0 0.5870149903265881 2 Q96P16 1 +Rna methylation 0.3625705648640109 1.40516072405795 0.1599734903846879 1.0 0.5870149903265881 35 Q9HCE5,Q9UI30,Q7Z4G4,Q9NXH9,Q9UBP6,Q9UJA5,Q8IZ69,Q96P11,Q969Y2,Q4G0J3 10 +Positive regulation of nucleocytoplasmic transport 0.3668014806700959 1.4049971068261338 0.1600221385947935 1.0 0.5870149903265881 32 Q16539,Q14012,Q9C0E2,P46934,Q92688 5 +Regulation of sodium ion transmembrane transport 0.457682912459305 1.398443824035642 0.161979830844025 1.0 0.5899287541015541 16 Q9H4A3,Q12955,Q9UHD1,O95747,P46934,Q96PU5 6 +Regulation of immune response 0.2796346507589815 1.3965808479482038 0.1625396528885296 1.0 0.5915216377038589 128 Q96FZ2,Q99497,P62942,Q14232,P98170,Q06124,P28070,P15311,Q96J02,P46108,P51617,Q16512,P09429,Q16539,P19474,Q6SZW1,Q9H4A3,Q9NR50,P04083,Q9Y3Z3,Q16543,Q9NUD5,O96028,P23396,P08238,P46109,P39019,Q13177,O00203,Q9NUQ9,Q01804,P49770,O95999,Q7Z739,Q13144,P51452,P25786 37 +Microtubule polymerization or depolymerization 0.3383542092800467 1.3963913989005166 0.1625966637620437 1.0 0.5915216377038589 48 P46821,Q15691,Q15555,O43670,Q8IWC1,P23396,Q13526,O75122,P78559,P16949,Q16512 11 +Snrna transcription by rna polymerase iii 0.8238387379491725 1.3956310964621716 0.1628256132191103 1.0 0.5920278225815641 2 P55199 1 +Pyrimidine nucleobase biosynthetic process 0.5524456681025043 1.3946252419407317 0.1631288791597094 1.0 0.5921506450555091 8 P11172,Q9NRF8,P17812 3 +Protein localization to golgi apparatus 0.525096279020079 1.3941625856079083 0.1632685133364111 1.0 0.5923313373217514 10 P83436,Q8TD16,Q96RL7 3 +Negative regulation of proteolysis 0.3146026207253701 1.393290392783436 0.163531994648165 1.0 0.5925845828197929 71 Q99497,P98170,Q9H2J4,P30086,P61201,P19474,Q96K76,P78559,Q96KB5,P30740,P78318,P04080,P06744,P08238,P20810,Q9C0C9,Q00535,P62081,Q15392,O94966,Q04323 21 +Positive regulation of neurotransmitter secretion 0.8229623137598581 1.391961430172023 0.163934077906424 1.0 0.592788503323723 2 Q15042 1 +Regulation of myeloid cell apoptotic process 0.6250012636626239 1.3903558813211312 0.1644208365906641 1.0 0.5942226725908211 6 P42771,P04083 2 +Tubulin complex assembly 0.6247229011290776 1.3890649736010732 0.164812993518105 1.0 0.5949292891469151 6 P17987,Q15813,Q15814,P61758 4 +Regulation of small molecule metabolic process 0.3303978146182341 1.3883915423862392 0.1650178503670436 1.0 0.5949292891469151 55 Q9UNI6,P04083,Q9UBM7,P34913 4 +Cellular pigmentation 0.5240326774073546 1.3883322467762975 0.165035897187987 1.0 0.5949292891469151 10 Q9BXS5,O00203,O14617 3 +Negative regulation of t cell differentiation 0.8337430516702315 1.387518306510627 0.1652837728768144 1.0 0.5949292891469151 3 P04083 1 +Positive regulation of cellular component biogenesis 0.2821203986039816 1.3865932597679624 0.1655658247711213 1.0 0.5949292891469151 126 Q16658,Q15691,Q99497,O14964,P17931,Q9UN37,P42345,O15144,O75351,P26038,Q15047,Q14203,P24941,P35080,Q16512,O95429,P62333,P27695,Q9H6U6,Q13535,Q96AC1,P07737,Q9UHD8,Q9UN86,Q9UQB8,P23396,O60504,P42858,P62195,A5YKK6,P78356,P49841,P36405,O75116,Q9BPX3,Q04637,Q92783,Q14195,Q13263,Q15042,P46821,P49427,Q15555,Q9NUL3,Q86VP6,P62330,Q13283,Q6IBS0,O75122,P11233,Q6UVJ0,Q7Z460,P07900,Q9UNN5 54 +Deoxyribonucleoside monophosphate catabolic process 0.8215016067776831 1.3858457551124286 0.1657940075434394 1.0 0.5949292891469151 2 O43598 1 +Purine deoxyribonucleotide catabolic process 0.8215016067776801 1.385845755112416 0.1657940075434432 1.0 0.5949292891469151 2 Q9Y3Z3 1 +Cellular carbohydrate biosynthetic process 0.4439358192717942 1.3844740904002677 0.1662133362492475 1.0 0.5954773437799128 19 P13807,O43505,Q9NPH2,P31751,P49841,A6NDG6,P35573,Q93063,P46976,P17174 10 +Regulation of focal adhesion disassembly 0.7040771428965542 1.3841708365373544 0.1663061509087 1.0 0.5954862285660787 4 Q15555 1 +Polysaccharide metabolic process 0.4349376925448802 1.383114718936158 0.1666296932027997 1.0 0.5955903851661221 21 P13807,O43505,P06737,P31751,P49841,P08237,P35573,Q93063,P46976,Q16851 10 +Regulation of actin cytoskeleton reorganization 0.5327246749167979 1.3824161638939374 0.1668439558335588 1.0 0.5955903851661221 9 P52565,O14786,Q9H6U6,Q9UQB8,Q9Y5K6,Q00535 6 +Hippocampus development 0.4435916759092739 1.382161008578357 0.1669222693508292 1.0 0.5955903851661221 19 Q00534,P46109,P49841,P43034,Q13144,P07196,P46108,Q00535 8 +Lactation 0.5130011580530137 1.38206330999371 0.1669522627913819 1.0 0.5955903851661221 11 P15531,P11172,Q99808,Q9UNS2,P61201,P07741 6 +Regulation of translational initiation 0.3430825604143445 1.3811579780294625 0.1672303921656035 1.0 0.5955925646679374 44 Q9Y6E2,P42345,P60228,Q9UBQ5,O15372,P78344,O75794,P23588,Q6PKG0,Q14240,Q9BPZ3,Q15056,P19525,P46199,O43432,P04792,Q04637,P49770,Q9Y5A9,O60841,Q86U44,Q7Z739,P55010,Q13144,Q7L1Q6,P55884 26 +Body fluid secretion 0.4793081699276766 1.3806957309426129 0.1673725344750345 1.0 0.5955925646679374 14 P15531,P11172,Q99808,P53621,Q9UNS2,Q9H4A3,P61201,P07741 8 +Positive regulation of cytoplasmic translation 0.5027539026707994 1.380686455457592 0.1673753876420203 1.0 0.5955925646679374 12 P67809 1 +Gmp biosynthetic process 0.5026138767978503 1.379887072649528 0.1676214174836325 1.0 0.5956659752302458 12 P22102,P55263,Q06203,P00492,P22234,P07741,P31939,P49915 8 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.6691195023985115 1.3783531862504546 0.1680942695076299 1.0 0.5958925485680064 5 P28161 1 +Establishment of epithelial cell polarity 0.5316218418671329 1.3764838250574154 0.1686718916671319 1.0 0.5961428248839861 9 Q9H4A6,P26038,P15311,P62330,P60953,O14745,Q7Z460 7 +Nucleobase metabolic process 0.4123210044962576 1.375558378730985 0.1689584000453319 1.0 0.5961428248839861 25 P49915,P11172,P22102,P42345,P04818,Q06203,P00492,P22234,P07741,Q14195,P34896,Q9P2T1,Q16555,Q9NRF8,P17812,P60891 16 +Regulation of wound healing 0.4504737363257398 1.3753541255731885 0.1690216838149529 1.0 0.5961428248839861 17 O75122,P46108,P04083 3 +Lymphocyte activation involved in immune response 0.4057180177561296 1.373209317518132 0.1696872839118837 1.0 0.5976759824245697 26 Q9UQ84,P04083,O96028,P13051 4 +Negative regulation of mapk cascade 0.3618777330795322 1.373089681255542 0.169724468518259 1.0 0.5976759824245697 33 Q8IV63,Q14152,P30153,P30086,P43034,P31689,Q53EL6,P51452,O75832,Q96J02,Q13526,Q96KB5,P78318 13 +Ncrna export from nucleus 0.620542538425675 1.3696727416973622 0.1707890812987005 1.0 0.5984943905061492 6 Q9H814,P05455 2 +Response to dietary excess 0.8291235433014502 1.3695031658335652 0.1708420458829014 1.0 0.5984943905061492 3 Q96E52 1 +Protein neddylation 0.6204253149917431 1.3691288067964271 0.1709590151056239 1.0 0.5984943905061492 6 P61081,Q8TBC4,Q96GG9 3 +Regulation of sodium ion transport 0.4456421137545544 1.3687786761896392 0.1710684683784253 1.0 0.5984943905061492 18 Q12955,O43865,O95747,P46934,Q96PU5 5 +Peptidyl tyrosine dephosphorylation 0.4453681381755548 1.366963712166657 0.171636679981197 1.0 0.598639679595794 18 Q9UNI6,O60942,Q13614,Q99504,Q06124,P51452,Q8NCE2 7 +Apoptotic dna fragmentation 0.6996008266632836 1.365197771737596 0.1721908985356675 1.0 0.5989699391219745 4 Q9UPY3 1 +Organelle inheritance 0.5293003172025297 1.3639920286712306 0.1725700745015288 1.0 0.5990426177535956 9 P36507,P63104,Q02750,Q99986 4 +Rescue of stalled ribosome 0.6190830729044486 1.3629000545736982 0.1729140115258016 1.0 0.5990871312509353 6 Q9H1I8,Q8N3C0 2 +Cell aging 0.369492862437647 1.3615292108235195 0.173346508818577 1.0 0.5994061738258424 31 Q16539,Q00534,P42771,Q13535,Q53EL6,P67809 6 +Protein heterotetramerization 0.5460687080635145 1.361417392784216 0.1733818227227774 1.0 0.5994061738258424 8 P31350,Q9Y285,Q9NSD9,P23921,O43809,Q8N684 6 +Negative regulation of fibroblast apoptotic process 0.8267095265926324 1.3600896929742343 0.1738015423211782 1.0 0.600274079147665 3 Q9UEE9,Q9BZZ5 2 +Response to inorganic substance 0.2971183415567151 1.3599299411395387 0.1738520950473896 1.0 0.600274079147665 113 P06744,P46821,P00374,Q86YQ8,Q99720,P04083,P0DP25,O60888,Q12955,O43865,P46108,P23396,P46934,O95831,Q96PU5 15 +Nucleoside salvage 0.6644148607949765 1.3577304060562263 0.1745492449032493 1.0 0.6014786316791529 5 P00491,P07741,Q13126 3 +Purine nucleoside biosynthetic process 0.6644148607949765 1.3577304060562263 0.1745492449032493 1.0 0.6014786316791529 5 P00491,P07741,Q13126 3 +Purine ribonucleoside salvage 0.6644148607949765 1.3577304060562263 0.1745492449032493 1.0 0.6014786316791529 5 P00491,P07741,Q13126 3 +Positive regulation of extracellular matrix assembly 0.8144902132632283 1.3564996497583215 0.1749402467318686 1.0 0.6018821014908547 2 O75122 1 +Regulation of extracellular matrix assembly 0.8144902132632283 1.3564996497583215 0.1749402467318686 1.0 0.6018821014908547 2 O75122 1 +Positive regulation of basement membrane assembly involved in embryonic body morphogenesis 0.8144902132632283 1.3564996497583215 0.1749402467318686 1.0 0.6018821014908547 2 O75122 1 +Regulation of phosphoprotein phosphatase activity 0.4353992813161446 1.3555002690022562 0.1752582229456574 1.0 0.6022438900434458 20 Q8IV63,P17931,P62942,P08238,Q15257,P49841,Q5H9R7,P0DP25,P42858 9 +Mapk cascade 0.297710611872078 1.3532716958262478 0.1759688480089887 1.0 0.6030543948648429 112 Q8IV63,P30153,P98170,P36507,P30086,Q06124,Q9UMX5,P15311,Q13043,Q96J02,Q13526,P51617,Q16512,P30046,P09429,Q16539,Q02750,Q96AC1,P31689,Q53EL6,O60271,P14174,Q96KB5,P23396,P78318,O60504,Q14152,P46109,O75832,Q13546,P10398,P43034,P51452,Q92905 34 +Telomerase holoenzyme complex assembly 0.6631879045821555 1.352350759813001 0.1762631334329452 1.0 0.6030543948648429 5 Q13535,P08238,Q96HR8 3 +Positive regulation of neurogenesis 0.3355555401627526 1.3516324998101377 0.1764929082116362 1.0 0.6030543948648429 46 P46821,Q02750,P55209,P53990,P42345,P27695,O43379,P43034,Q9UPY3,Q9UIW2,P07196,P13010,Q16706,Q9UQB8,Q6IBS0 15 +Positive regulation of nervous system development 0.3346198790214101 1.3497814433026958 0.1770860989183136 1.0 0.6039066549764736 47 P46821,Q02750,P55209,P53990,P42345,P27695,O43379,P43034,Q9UPY3,Q9UIW2,P07196,P13010,Q16706,Q9UQB8,Q6IBS0 15 +Regulation of short term neuronal synaptic plasticity 0.8127373648846032 1.3491659369210187 0.1772836731467699 1.0 0.6040962674400427 2 Q15042 1 +Collagen fibril organization 0.5068547529113516 1.347668015191985 0.1777651838527312 1.0 0.6046051486260173 11 Q96AY3 1 +Inflammatory response 0.3107950450377268 1.3471564144640151 0.177929862059976 1.0 0.6046051486260173 71 P09429,Q16539,Q96AQ6,P98170,Q8IV08,P04083,P42785,O00203,P28070,P60900,Q53EL6,P25786,Q96J02,Q9UNH7,Q96KB5,O60684 16 +Phosphatidylinositol phosphate biosynthetic process 0.5164633268037953 1.346807849014559 0.1780421261717126 1.0 0.6046051486260173 10 P42356,P78356,Q96Q15,Q8NEB9,Q01968 5 +Negative regulation of glial cell proliferation 0.823172788029926 1.3462995304522696 0.1782059372133815 1.0 0.6046051486260173 3 Q96G23 1 +Negative regulation of protein localization to cell periphery 0.543166520339479 1.3462928174439284 0.178208101301631 1.0 0.6046051486260173 8 P41240,Q9ULT8,Q9HD26,Q9NQ48,Q13492,Q96CW1,O75608 7 +Hippo signaling 0.5784258292017666 1.343492876834652 0.17911243100621 1.0 0.6058688495623064 7 Q16539 1 +Regulation of dendrite extension 0.6611540670657345 1.343432290358281 0.1791320369837583 1.0 0.6058688495623064 5 Q96PU5 1 +Regulation of organ growth 0.4959140641606855 1.3416196802021112 0.1797193417672153 1.0 0.6068610284813686 12 Q16539 1 +Negative regulation of gluconeogenesis 0.8095238095238109 1.3357242837758374 0.1816394090648607 1.0 0.6093470659315837 2 Q13043 1 +Meiotic cell cycle 0.3143779956164821 1.3322769842438529 0.182769187307235 1.0 0.6109606910391954 63 Q9UQ84,Q8N2A8,Q92791,P33981,O95067,Q14674,O60921,Q9Y620 8 +Pigment cell differentiation 0.5759875532397315 1.3315113699507903 0.1830208063291662 1.0 0.6114917158245637 7 Q9BXS5,Q92995,O14617 3 +Enzyme linked receptor protein signaling pathway 0.2690540474907346 1.328076063848122 0.1841529800084935 1.0 0.612385156516058 132 P62942,P98170,P33981,Q9H1E3,Q13526,Q96B36,Q93062,P46108,Q16512,P16949,Q8WUH2,Q16539,Q96AC1,Q53EL6,Q9UNH7,Q9UQB8,P04792,P46934,P43490,P51452,Q8N0X7 21 +Deoxyribonucleoside monophosphate biosynthetic process 0.6576023391812764 1.3278551853544611 0.1842259519530933 1.0 0.612385156516058 5 P04183,P33316,P04818,P55263 4 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4466015848193083 1.3270760588519088 0.1844835240325979 1.0 0.612385156516058 16 Q9UQ84,O96028 2 +Somatic diversification of immunoglobulins involved in immune response 0.4466015848193083 1.3270760588519088 0.1844835240325979 1.0 0.612385156516058 16 Q9UQ84,O96028 2 +B cell activation involved in immune response 0.4466015848193083 1.3270760588519088 0.1844835240325979 1.0 0.612385156516058 16 Q9UQ84,O96028 2 +Pyrimidine deoxyribonucleoside metabolic process 0.8071866783523243 1.3259516582690096 0.1848557103329602 1.0 0.612385156516058 2 P04183 1 +Reelin mediated signaling pathway 0.8179427235534825 1.3259110735646058 0.1848691546018535 1.0 0.612385156516058 3 P46108,P46109 2 +Corpus callosum development 0.8179427235534782 1.3259110735645885 0.1848691546018592 1.0 0.612385156516058 3 Q96P11,Q00535 2 +Organic hydroxy compound biosynthetic process 0.3257231017735026 1.3256646046977854 0.184950816508699 1.0 0.612385156516058 54 P00374,Q16850,Q15392,Q15125,Q9UBM7 5 +Synaptic vesicle budding 0.8176073782822346 1.324604001790231 0.1853025279351303 1.0 0.6132099719620379 3 O00203 1 +Positive regulation of filopodium assembly 0.57401989467524 1.3218402161191865 0.1862213634746026 1.0 0.6146062036241884 7 Q16658,O14786,Q9H6U6,Q14195,P11233,Q06787 6 +Cytokinesis 0.3074044442802264 1.3216526025905928 0.1862838584407051 1.0 0.6146062036241884 68 Q9UN37,Q6DKK2,P53990,P41208,O75351,Q9NZZ3,Q8NEB9,P40818,Q12955,Q14674,Q13526,P16949,P0DP25,Q15019,Q9HD42 15 +Negative regulation of developmental process 0.2923576503326193 1.3213510725513742 0.186384332013997 1.0 0.6146300733548118 115 Q06124,Q9UPY3,Q9GZS3,Q13043,Q96E52,P67809,P09429,Q00534,P04083,Q86VS8,Q96AC1,Q53EL6,O60271,Q96G23,Q92688,P16989,P49841,Q8WX92,O15347,O95747,P49591,Q86X55,Q9P265,O94966,Q15051,Q8N0X7 26 +Negative regulation of hemopoiesis 0.5116243471371076 1.320237354876025 0.1867557837590188 1.0 0.6151429978130117 10 P09429,P04083,O15347 3 +Regulation of glycogen metabolic process 0.6558218939688343 1.3200455086780627 0.1868198242751289 1.0 0.6151429978130117 5 P49841 1 +Regulation of glucan biosynthetic process 0.6558218939688343 1.3200455086780627 0.1868198242751289 1.0 0.6151429978130117 5 P49841 1 +Cellular response to biotic stimulus 0.3464366110401986 1.3172380551243286 0.1877588416271915 1.0 0.6157742706499736 39 P09429,Q16539,O95999,P49841,Q9NZZ3,Q53EL6,Q9NUQ9,O43823,Q9NQ88 9 +Thymus development 0.5727075038609358 1.3153887414422667 0.1883792873559431 1.0 0.6171949613570462 7 O95067,P46109 2 +Urate metabolic process 0.8042652643879633 1.3137399774310952 0.1889337227036454 1.0 0.6187039741989222 2 P00491 1 +Arf protein signal transduction 0.6871931467322057 1.3125874030028457 0.1893220166324956 1.0 0.6190529432745094 4 Q15555 1 +Protein polyubiquitination 0.3232235872385616 1.3108541175627744 0.1899070547749441 1.0 0.6194406218859098 55 P19474,P49427,O95155,P98170,Q96FW1,Q16763,P52888,Q8IYU2,Q9C0C9,P68036,Q13309,Q96J02,Q15386,Q9NZJ0,Q7Z6Z7,P46934,Q8TDB6,Q96PU5 18 +Glycerophospholipid biosynthetic process 0.3359890219834328 1.3108441551617196 0.189910421242631 1.0 0.6194406218859098 44 Q13614,P42356,Q96Q15,Q8NEB9,Q9NPH0,Q9HBU6,Q8NCE2,P35790 8 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.6074842454849001 1.3090404334624 0.1905206547953786 1.0 0.6202715036190167 6 P17612,P0DP25,P28161 3 +Regulation of myotube differentiation 0.6058585032353624 1.3014874192322916 0.193091668042344 1.0 0.6251769527186305 6 Q9BYT8,Q16539,Q96TA1,P42345 4 +Axoneme assembly 0.6839916661860836 1.2990108373650964 0.1939402100021003 1.0 0.62664521021078 4 A0AVF1,Q15555 2 +Negative regulation of protein localization to cell surface 0.6834011789684693 1.29650677849062 0.1948009462355679 1.0 0.6285500918183378 4 Q9HD26,Q96PU5 2 +Regulation of erythrocyte differentiation 0.4381167434484792 1.2946091881270607 0.1954550811593507 1.0 0.6289389545072299 17 Q16539,Q00534,Q15648,P42224,O95251,Q96KR6,O43251,P78527,Q99873 9 +Response to mechanical stimulus 0.4264406668063233 1.2942907000820494 0.1955650275907983 1.0 0.6289389545072299 20 P06744,Q16539,P46821,O95817,Q99439,P42858 6 +Histone dephosphorylation 0.7995910020449888 1.2942118891918788 0.1955922411848059 1.0 0.6289389545072299 2 Q99504 1 +Regulation of cellular protein catabolic process 0.3053868235505422 1.2941089518686677 0.1956277898760521 1.0 0.6289389545072299 96 P62191,Q99497,P26038,O14980,Q9H2J4,Q92995,P15311,P07900,P43686,P24941,Q15370,P60520,P54578,Q9GZU8,P48729,P62333,Q9NZL4,Q96KB5,P17612,P17980,P78559,P08238,P62195,P49841,O75150,P35241,O75832,P61289,Q9GZP4,Q9UL46,P62081,P54727,P10398,Q9UL15,P54725,P19784,O94966,O14965,Q9Y5A7,Q04323,Q9UNN5 41 +Peptidyl threonine modification 0.3515360338718372 1.2926944414858943 0.1961167610114547 1.0 0.6296938664135373 34 P42345,Q9H4A3,P49841,O75116,O95747,P0DP25,Q9Y4B6,P33981,Q04637,P06493,P19784,P17612,Q16512,Q99986,Q00535 15 +Gmp metabolic process 0.4338089038606351 1.290333194420506 0.1969349963601421 1.0 0.6296938664135373 18 P22102,Q9UDY2,P55263,Q06203,P00492,P22234,P07741,P31939,Q9P2T1,P49915 10 +Oocyte maturation 0.6029275830536877 1.287869149216139 0.1977915162755661 1.0 0.6296938664135373 6 Q15645,Q5TAX3,Q9Y5A9,P30153 4 +Positive regulation of myeloid cell differentiation 0.4254132871942526 1.2872690169891612 0.1980005387113765 1.0 0.6296938664135373 20 Q16539,Q15648,P42224,O95251,Q96KR6,Q9GZP4,P78527,Q99873,Q13546 9 +Regulation of mitotic spindle assembly 0.475191783354597 1.286873455429436 0.1981383987411702 1.0 0.6296938664135373 13 Q9NZZ3,Q9HD42 2 +Microtubule cytoskeleton organization 0.2876700744097845 1.2852381514220488 0.1987090755034257 1.0 0.6296938664135373 189 Q15018,Q15691,P30153,O75351,Q9H6D7,P33981,P15311,Q9Y266,Q14203,P24941,Q13526,P16949,Q16512,Q96CS2,Q9BVA1,Q9HC35,Q9NZZ3,Q15813,Q9HBM1,Q15004,Q86VS8,Q14674,Q9Y6G9,P07437,P78559,P23396,Q8TD16,A0AVF1,P42858,O43670,P41208,P49841,Q8IWJ2,Q12873,O43379,Q9BUF5,Q9UHD1,Q9BV86,O43237,Q00535,Q9HD42,P46821,Q15555,Q8IWC1,Q9P287,Q86Y56,O95067,P43034,P07196,O75122,Q6UVJ0,Q7Z460 52 +Deoxyribonucleoside metabolic process 0.8074225599064897 1.2849230369635585 0.1988191798494503 1.0 0.6296938664135373 3 P00491,P04183 2 +Positive regulation of nitric oxide synthase biosynthetic process 0.6804508253520357 1.2839956747100707 0.1991434688262336 1.0 0.6296938664135373 4 P43490,Q02952 2 +Nitric oxide synthase biosynthetic process 0.6804508253520357 1.2839956747100707 0.1991434688262336 1.0 0.6296938664135373 4 P43490,Q02952 2 +Protein catabolic process 0.3262770257304511 1.28316610033858 0.1994338897936942 1.0 0.6296938664135373 305 Q9H2J4,O75351,P49721,P28070,Q13200,Q96E52,Q15370,Q96K76,P20618,Q05639,Q96PU5,Q4G0X4,Q16850,Q96RU2,O75832,Q9UKS6,P46934,Q13546,Q9HD42,P54727,P28072,P10398,Q13309,P49720,Q04323,Q8IYU2,Q9UBU6,Q93034,Q9UJY5,Q99497,O95155,Q92995,Q8WW12,O60493,P15311,Q9H1I8,P28074,P24941,Q13526,P48729,Q9NZZ3,Q8N511,Q8N3C0,P60900,Q96KB5,P25788,P08238,Q99436,O95817,Q13107,P68036,P61289,Q9GZP4,Q7Z6Z7,Q8NBM8,P28066,Q8TDB6,P49427,P62081,Q9UNS2,Q96RL7,O60502,O95260,O14965,Q9UN37,P51665,P42345,O43847,Q6NTF9,Q15008,Q96J02,Q99460,P48556,Q9GZU8,Q9H9H4,P62333,Q16763,P63208,O14773,Q9NXV2,Q13596,P17612,P17980,P78559,P62195,P25789,Q93008,Q92783,Q15386,Q9UMY4,Q9UBV2,P54725,P19784,O94966,P25786,P07900,O43242,P62191,P26038,Q9UNM6,Q5T4S7,Q9UHG3,Q86Y37,P25787,P49841,P40818,Q9NZJ0,Q9UL46,Q9Y5X3,O94888,Q5VWZ2,Q9UNN5 112 +Regulation of synaptic vesicle exocytosis 0.4854609475643449 1.2818594345044785 0.1998919603388049 1.0 0.6296938664135373 12 P49841,Q4J6C6,P35080,Q15042,P0DP25 5 +Monocyte chemotaxis 0.5307950634542284 1.2817588022374582 0.1999272702710692 1.0 0.6296938664135373 8 P09429,P39019,P04083 3 +Positive regulation of cell development 0.3099984678940343 1.2817265369484772 0.199938592506389 1.0 0.6296938664135373 63 P42345,Q9UPY3,P46108,Q02750,P55209,P27695,Q96AC1,P13010,Q9UQB8,P53990,P46109,O43379,Q16706,P46821,Q9NUL3,P43034,Q9UIW2,P07196,Q6IBS0,O14965 20 +Positive regulation of inclusion body assembly 0.6796267659739518 1.2805013658742224 0.2003688646819597 1.0 0.6296938664135373 4 P49427,P62333 2 +Negative regulation of ubiquitin protein transferase activity 0.4510645449170946 1.2797404596294883 0.2006364300859413 1.0 0.6296938664135373 15 P62081,Q99497,P62841,O60566,Q9UL15,Q8TDB6 6 +Purine nucleoside monophosphate metabolic process 0.3994219011910046 1.2791801830420382 0.2008336126196344 1.0 0.6296938664135373 25 P00491,P22102,Q9UDY2,P55263,Q06203,P30520,P07741,P31939,Q01433,Q9P2T1,P11908,P49915 12 +Negative regulation of cell size 0.6791453320773626 1.278459951891645 0.2010872968944523 1.0 0.6296938664135373 4 P42345,Q96B36 2 +Regulation of oxidoreductase activity 0.4356024053866287 1.2781680356495324 0.201190183990827 1.0 0.6296938664135373 17 P00374 1 +Response to isoquinoline alkaloid 0.8056691992986648 1.2780956305103963 0.2012157094265805 1.0 0.6296938664135373 3 P06744,P63151 2 +Response to interleukin 7 0.5133435368711458 1.2780176391216913 0.2012432068604366 1.0 0.6296938664135373 9 P67809,P31948,P51858 3 +Somatic diversification of immune receptors via somatic mutation 0.6003462580859455 1.275874002021385 0.2020000626242444 1.0 0.6296938664135373 6 Q9UQ84 1 +Spinal cord development 0.4619365800304569 1.275492245519813 0.2021350670970725 1.0 0.6296938664135373 14 P18074,P21359,O75312,O95817,P07196,Q9UKA9,Q14203,P25325 8 +Golgi localization 0.5997257604583713 1.2729904908996243 0.2030214161965999 1.0 0.6296938664135373 6 Q9Y678,P48444,Q86VS8 3 +Regulation of guanyl nucleotide exchange factor activity 0.6445134406267535 1.2704346070727746 0.2039298624942214 1.0 0.6305373609577427 5 Q96AQ6,P16949 2 +Regulation of phosphatase activity 0.4094568546520008 1.2695872105676576 0.2042317074594453 1.0 0.631031261791195 23 Q8IV63,P17931,P62942,P08238,Q15257,P49841,Q5H9R7,Q9UHD1,P0DP25,O95429,P42858 11 +Regulation of protein polymerization 0.3023581080871241 1.2671973315485503 0.205084739696745 1.0 0.6323286267918349 67 O15144,Q15691,P47755,P42345,P07900,P35080,Q14203,P16949,Q16512,O95429,P07737,Q9UQB8,P23396,P36405,Q9BPX3,P35241,Q14019,Q9NUQ9,Q02790,P46821,P62330,Q6IBS0,Q7Z460,P04350 24 +Extracellular vesicle biogenesis 0.5013605140620978 1.2638369081299567 0.2062885708796944 1.0 0.6336606044594384 10 Q92783,Q9UN37,Q92905 3 +Negative regulation of calcium ion transmembrane transport 0.5013218681005288 1.2636244753741777 0.2063648444520023 1.0 0.6336606044594384 10 P0DP25,P28161 2 +Negative regulation of phosphatase activity 0.491337404808748 1.260726781019742 0.2074073015983479 1.0 0.6353838290721506 11 Q15257,P17931,P62942,P49841,Q9UHD1,O95429 6 +Actin filament depolymerization 0.4127578956437892 1.2599436846113818 0.2076896783076742 1.0 0.6358989128677142 22 P58546,P47755,P60981,Q9Y281,Q9BPX3,P23528,Q9UEY8,P35241,Q6IBS0,Q9UHB6,Q13045,Q12792 12 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.7905346187554865 1.2564201987967902 0.2089636621030264 1.0 0.6368416368854138 2 P23396 1 +Regulation of reproductive process 0.4207917567188764 1.2556822780631878 0.2092311870215804 1.0 0.6373587430414981 20 Q9Y5A9,P30153,Q15645,Q86U44,P33981,Q7Z739,Q13043,P30307,O14965 9 +Regulation of dendrite development 0.3962418316036625 1.2554189575514314 0.2093267109655405 1.0 0.6373587430414981 25 Q86X55,Q9UQB8,P46108,P46934,Q96PU5 5 +Negative regulation of peptidyl threonine phosphorylation 0.7896581945661835 1.2527664530345584 0.2102907137006786 1.0 0.6394079265290588 2 P0DP25 1 +Cap dependent translational initiation 0.7896581945661707 1.252766453034506 0.2102907137006977 1.0 0.6394079265290588 2 O15371 1 +Establishment of protein localization to vacuole 0.4160819212832513 1.2522363174794058 0.2104837660770524 1.0 0.6396937293516192 21 Q9UN37,Q96RL7,Q92783,O00203,P46934,P20645 6 +Negative regulation of amyloid fibril formation 0.594988394581974 1.2509747732596963 0.2109436813508245 1.0 0.6402121305085798 6 Q9UHV9,Q9NQP4,O15212,Q99471 4 +3 utr mediated mrna stabilization 0.5076256174232385 1.2471785667853217 0.2123320299626683 1.0 0.642053312667396 9 Q16539 1 +Trna threonylcarbamoyladenosine metabolic process 0.5941227651046893 1.246951968045883 0.2124151099248321 1.0 0.642053312667396 6 Q9NPF4,Q96SZ6,Q9Y606 3 +Diol biosynthetic process 0.524006200216556 1.2463188781006684 0.212647349902411 1.0 0.6421307057062271 8 P00374 1 +Diol metabolic process 0.524006200216556 1.2463188781006684 0.212647349902411 1.0 0.6421307057062271 8 P00374 1 +Positive regulation of dendritic spine morphogenesis 0.5237497623800684 1.244980021930855 0.2131390939419088 1.0 0.643026502180807 8 Q9UQB8,P43034 2 +Regulation of dna demethylation 0.6705307529927835 1.241939258384298 0.2142589739791254 1.0 0.6449292951919611 4 Q01804,Q93008 2 +Response to testosterone 0.4878788943284093 1.2413396883770351 0.2144802889973225 1.0 0.6453008056003423 11 P49321,Q13126 2 +Regulation of jun kinase activity 0.592463551006939 1.2392412940574813 0.2152561521975924 1.0 0.6455070282239691 6 Q16512,P23396,Q53EL6 3 +Myeloid cell apoptotic process 0.5568997443709965 1.237641538425143 0.2158490050933219 1.0 0.6460363378784715 7 P42771,P04083 2 +Cytokine production 0.3001492125699089 1.236774090119416 0.2161709637031097 1.0 0.6465512671192828 98 Q99497,Q06124,P15311,Q9UPY3,Q96J02,O43823,P30046,P09429,Q16539,P19474,P04083,Q9NUD5,Q53EL6,P14174,P23396,P30740,Q8NCF5,P04792,Q9Y6M1,Q9NUQ9,Q13546,O60684,P00491,O95999,Q8IV08,P49591,Q13283 27 +Rna catabolic process 0.2550652976621481 1.235046787422925 0.2168130917555282 1.0 0.6481777328128989 137 Q16539,P16989,Q96Q15,Q96C86,P51114,Q5TAX3,Q9BQ61,Q96HR8,Q9HCE1,Q9BQG2,Q969T7,Q14011,P67809,Q9H814,P05455 15 +Positive regulation of calcium ion transport into cytosol 0.5215410014151856 1.2334479135786398 0.2174086982799288 1.0 0.6491691876580826 8 P0DP25,P28161 2 +Limbic system development 0.3932483057750566 1.233057345681009 0.2175543698334641 1.0 0.6491691876580826 25 Q00534,P46109,P49841,P43034,Q13144,P07196,P46108,Q15042,Q00535 9 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.555643245078516 1.231460518806534 0.2181506743080477 1.0 0.6498189087386581 7 Q93034,Q13620,Q13616,P63208,Q13309 5 +Cell cycle g1 s phase transition 0.299736380067074 1.229641019575009 0.2188315622308423 1.0 0.6509793152898734 68 Q93034,Q13620,O00716,P42771,P15927,P24941,P49321,Q00534,P04083,P27695,Q13642,Q06323,Q86Y37,Q07864,P06730,P31350,O75312,P11802,P15170,Q04637,P35241,P61289,P78527,Q9UL46,P23921,Q00535,P49427,O95905,Q9UPP1,Q7Z7L1,Q96DY7,P62753,Q13309,Q6UVJ0 34 +Positive regulation of muscle cell differentiation 0.5043301153273938 1.229401698985774 0.2189212335783943 1.0 0.6509793152898734 9 Q16539 1 +Regulation of cell cell adhesion 0.3187084824883312 1.2292827427478086 0.2189658152657339 1.0 0.6509793152898734 52 P09429,Q16539,Q9Y5A9,P00491,O95999,Q9H4A3,P04083,P23396,Q12955,Q06124,O00203,P51452,Q96J02,Q9NUQ9,P51617,O14617 16 +Aggrephagy 0.6349938541777853 1.2286767649187122 0.2191930211163004 1.0 0.6509793152898734 5 P42858 1 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.7929512593155068 1.2286193149287548 0.2192145702469341 1.0 0.6509793152898734 3 Q9NPI6 1 +Protein depolymerization 0.3227160738266672 1.228349986165673 0.2193156140565666 1.0 0.6509793152898734 47 Q99961,Q9UN37,P47755,O75351,P16949,Q12792,Q9Y281,P78559,P48681,Q9BPX3,P23528,P35241,Q13045,P58546,P46821,P60981,Q9UEY8,Q6IBS0,O75122,Q9UHB6,Q7Z460 21 +Positive regulation of protein depolymerization 0.6671725771471287 1.2277081933605418 0.2195565296052268 1.0 0.6512935508082831 4 P60981,P48681 2 +Positive regulation of wound healing 0.5191822390546186 1.2211325316131754 0.222035844211865 1.0 0.6572340750088076 8 P04083 1 +Maintenance of protein location 0.3530560017023086 1.220342378455166 0.2223351110140798 1.0 0.6577329114907147 31 P24390,Q9HD26,Q99497,Q9UNN5,Q96RL7,P63208,Q12955,O75832,Q9UN86,Q6IBS0,O00221,P31946,Q00535 13 +Positive regulation of viral life cycle 0.5189961221216316 1.2201608023791624 0.2224039228933256 1.0 0.6577329114907147 8 P19474,Q9UN37 2 +Negative regulation of fatty acid transport 0.7814782354659641 1.2186995432114076 0.2229582514115615 1.0 0.6590748383220058 2 P31751 1 +Negative regulation of protein catabolic process 0.3286502613339609 1.218259295293751 0.2231254530702777 1.0 0.6590748383220058 43 P62081,Q16850,Q9H2J4,Q13526,P78559,Q96KB5 6 +Membrane depolarization during action potential 0.7808939526731045 1.2162687758255404 0.2238825518881406 1.0 0.6603283141148203 2 Q12955 1 +Rna modification 0.2989621406407083 1.2145160285631695 0.2245507328667879 1.0 0.6620028761439474 69 Q9UI30,Q6NYC1,Q7Z4G4,Q9NXH9,Q96SZ6,Q8WWH5,Q9NX74,Q9UBP6,Q9UJA5,Q9NPF4,Q9NXG2,Q9H9T3,Q8IZ69,Q96P11,Q96HR8,Q969Y2,P05455 17 +Leukocyte cell cell adhesion 0.3280828183331341 1.2127055166708154 0.2252424299065647 1.0 0.6630850194139603 43 P09429,Q13630,P00491,O95999,Q9H4A3,P04083,O00203,P15311,Q06124,P51452,Q96J02,Q9NUQ9,P23396,O14617 14 +Positive regulation of supramolecular fiber organization 0.3239544597434858 1.212236575423471 0.2254218344224243 1.0 0.6630850194139603 45 P46821,Q15691,P60981,Q96AC1,P07737,P35080,Q9UQB8,P23396,Q16512,O95429,O60504 11 +Regulation of microtubule polymerization 0.4059648405276018 1.21202032123216 0.2255046019237316 1.0 0.6630850194139603 22 P46821,Q15691,P36405,P23396,Q14203,P16949,Q16512,Q7Z460,P04350 9 +Inner cell mass cell proliferation 0.5515529849637468 1.211340734226249 0.2257648431710581 1.0 0.6630850194139603 7 Q9BRX2,P61201,Q9BRT9 3 +Regulation of epithelial cell migration 0.3201921855249536 1.2098771256809355 0.2263260457647771 1.0 0.6630850194139603 48 P09429,Q16539,P06744,Q15555,P04083,P42785,P04792,P07737,O75122 9 +Virion assembly 0.4250525374584387 1.209178909212274 0.2265941186292637 1.0 0.6632808303748252 17 Q9NZZ3,P46934,Q9HD42 3 +Positive regulation of cell cell adhesion 0.3515506407507656 1.2074255812801196 0.2272682887507848 1.0 0.6646639571628988 31 P09429,P00491,O95999,P04083,Q12955,Q06124,O00203,Q9NUQ9,P23396,O14617 10 +Protein polymerization 0.3009461916927747 1.2030935426075302 0.2289401239617348 1.0 0.6676870187131414 88 O15144,Q15691,P47755,P42345,P07900,Q14203,Q13526,P35080,P16949,Q16512,O95429,P57737,Q16763,P07737,Q9UQB8,P23396,O43670,P36405,Q9BPX3,P23258,P35241,Q14019,Q9NUQ9,Q02790,Q13045,P46821,Q8IWC1,P62330,P07196,Q6IBS0,O75122,Q7Z460,P04350 33 +Postsynapse organization 0.3388535816889294 1.2028731874698462 0.2290253975409548 1.0 0.6676870187131414 36 Q12756,O60678,Q16352,P61160,Q9Y4F1,Q9UQB8,P46109,P23528,P12814,Q00535,Q13614,Q9NUL3,Q96HC4,P43034,Q9NQX3,P62330,Q14247,P07196,Q15334 19 +T cell migration 0.4902297674675784 1.20264877933374 0.2291122627926465 1.0 0.6676870187131414 10 O95747,P46108,P46109 3 +Receptor catabolic process 0.4900966443530941 1.2019170537304762 0.2293956664227685 1.0 0.6679223644253048 10 Q13614,Q99570,Q96J02,P46934,Q00535 5 +Wound healing spreading of epidermal cells 0.6279824840209105 1.1979365226317291 0.2309417299513025 1.0 0.6712125055395323 5 Q96AC1,O75122,Q7Z460 3 +Actin filament bundle organization 0.3264420657516809 1.1966524322211434 0.2314420547772082 1.0 0.6712125055395323 43 Q16658,P42345,P15311,P35080,P16949,Q16512,O95429,Q15942,Q96AC1,P07737,Q9UQB8,O60504,O75116,Q13177,P35241,Q14195,O75122,Q9UHB6,Q7Z460 19 +Ribonucleoside metabolic process 0.5483653590397292 1.1956633076361878 0.2318279755645798 1.0 0.671670692412686 7 P00491,P07741,Q13126 3 +Purine ribonucleoside metabolic process 0.5483653590397292 1.1956633076361878 0.2318279755645798 1.0 0.671670692412686 7 P00491,P07741,Q13126 3 +Cellular response to insulin like growth factor stimulus 0.7843366452366948 1.1951642550665635 0.2320228612265329 1.0 0.6717148446224441 3 P46108,Q96A49 2 +De novo amp biosynthetic process 0.5476187689253991 1.1919918481717766 0.2332644416651665 1.0 0.6723577327735034 7 P31939,P30520,Q06203,P22102 4 +Regulation of dendritic cell differentiation 0.775051124744387 1.1919821476058792 0.2332682453731251 1.0 0.6723577327735034 2 P09429 1 +Positive regulation of dendritic cell differentiation 0.775051124744387 1.1919821476058792 0.2332682453731251 1.0 0.6723577327735034 2 P09429 1 +Retina morphogenesis in camera type eye 0.6585548577975746 1.1912107128514209 0.2335708750077856 1.0 0.6723577327735034 4 Q15555,Q16706 2 +P38mapk cascade 0.547296004210382 1.1904046674449813 0.2338873794439067 1.0 0.6726813286624054 7 Q16539,P15311 2 +Copii coated vesicle cargo loading 0.4879115041845735 1.18990699411736 0.2340829491940521 1.0 0.6728518300572254 10 Q15436,Q15437,O95486,Q9NR31 4 +Negative regulation of intracellular protein transport 0.4786432339632885 1.1895758011776874 0.2342131616583969 1.0 0.6728518300572254 11 Q9UHD1,O95429,O95817,Q00535 4 +Regulation of rac protein signal transduction 0.5815749811043769 1.1886526255005152 0.2345763900829367 1.0 0.6729480053391802 6 P46108,P62330,Q68EM7,P50570 4 +Response to mineralocorticoid 0.5467955916587506 1.1879439859421403 0.2348554786681806 1.0 0.6729480053391802 7 P0DP25,P07196,O95831 3 +Negative regulation of microtubule polymerization 0.5813974757507107 1.1878282288137236 0.2349010904575177 1.0 0.6729480053391802 6 P16949,Q15691,P04350 3 +Synapse maturation 0.6256565647469876 1.1877434250163528 0.234934509684225 1.0 0.6729480053391802 5 P07737,P07196 2 +Response to muscle stretch 0.6256484151625791 1.1877077150378317 0.2349485831729134 1.0 0.6729480053391802 5 Q16539 1 +Pyrimidine deoxyribonucleotide biosynthetic process 0.6574101140017637 1.1863654918543851 0.2354779932578696 1.0 0.6729480053391802 4 P33316,P04818,P23919 3 +Positive regulation of wound healing spreading of epidermal cells 0.7735904177622074 1.1859168019286264 0.2356551571593665 1.0 0.6729480053391802 2 Q96AC1 1 +Negative regulation of lipid transport 0.7817066043249568 1.1849619330803305 0.2360324982073831 1.0 0.6729480053391802 3 Q06124,P31751 2 +Protein localization to early endosome 0.5461511266393484 1.1847750939614972 0.2361063824714837 1.0 0.6729480053391802 7 O75116,P26038,Q8TDB6,P15311 4 +Regulation of cell adhesion 0.2920645008422459 1.184773138699477 0.2361071557530882 1.0 0.6729480053391802 105 P30153,P42771,Q12955,Q06124,Q13043,Q96J02,P46108,P51617,O95429,P09429,Q16539,Q00534,Q9H4A3,P04083,Q9H6U6,Q96AC1,P23396,Q13630,P46109,P49841,O00203,Q9NUQ9,O14617,P00491,O95999,Q9UIW2,P51452,O75122,Q7Z460,Q9UNN5 30 +Regulation of postsynaptic membrane potential 0.4577001813263435 1.1839568232322135 0.2364301547884619 1.0 0.6729480053391802 13 Q13614,P49841,Q9UQB8,Q15042,Q00535 5 +Chemical synaptic transmission postsynaptic 0.4577001813263435 1.1839568232322135 0.2364301547884619 1.0 0.6729480053391802 13 Q13614,P49841,Q9UQB8,Q15042,Q00535 5 +S adenosylmethionine cycle 0.7808682297181142 1.1817109950998137 0.2373203940979282 1.0 0.6743172577127341 3 O43865 1 +Purine nucleobase metabolic process 0.4770768973205137 1.1807999247027854 0.2376822140068912 1.0 0.6746090105394895 11 P22102,Q06203,P00492,P07741,P34896,Q9P2T1,P49915,P60891 8 +Regulation of podosome assembly 0.6560534931744866 1.1806245323558622 0.2377519135255199 1.0 0.6746090105394895 4 P26038,Q9BPX3 2 +Positive regulation of podosome assembly 0.6560534931744866 1.1806245323558622 0.2377519135255199 1.0 0.6746090105394895 4 P26038,Q9BPX3 2 +Regulation of calcium ion transport into cytosol 0.4351689853285492 1.1804219798736626 0.2378324242253904 1.0 0.6746090105394895 15 P0DP25,P62942,P28161 3 +Purine nucleobase biosynthetic process 0.4950426899122848 1.1793060900787622 0.2382763140927422 1.0 0.6749967608506044 9 P22102,Q06203,P00492,P07741,P34896,P49915,P60891 7 +Neuroepithelial cell differentiation 0.6550809621813987 1.1765096991805652 0.2393912588853253 1.0 0.6767011914974548 4 P46821,Q9P287 2 +Rrna base methylation 0.6229950216820446 1.1760829404266788 0.2395617342859841 1.0 0.6768928214372943 5 Q9UI30,Q96P11 2 +Vesicle cytoskeletal trafficking 0.4128393326766645 1.1752433157117554 0.2398973852381924 1.0 0.6771658882698853 19 Q9Y496,P27695,O00203,P43034,Q12756,O14617,Q92572,P42858 8 +Regulation of dna damage response signal transduction by p53 class mediator 0.4851349708445601 1.1746492386882323 0.2401350754645541 1.0 0.6771658882698853 10 Q13535,O75832 2 +Utp biosynthetic process 0.6226466482649415 1.1745569789911512 0.2401720034549441 1.0 0.6771658882698853 5 P15531 1 +Utp metabolic process 0.6226466482649415 1.1745569789911512 0.2401720034549441 1.0 0.6771658882698853 5 P15531 1 +Inositol phosphate catabolic process 0.65442764390249 1.173745829020424 0.2404968477111313 1.0 0.6775022308169991 4 Q13614 1 +Protein k63 linked deubiquitination 0.4664500368465473 1.173154775725762 0.2407337439032413 1.0 0.6775817051887418 12 Q15018,Q01804,Q92995,P40818 4 +Glial cell proliferation 0.5775509424944334 1.1699670950936143 0.2420142109225085 1.0 0.6791646140490321 6 Q96G23 1 +Regulation of body fluid levels 0.3168938396931788 1.16907912103028 0.242371755141475 1.0 0.6798785574011078 47 O00299,Q9C0E8,P61201,P16949,Q93063,Q16539,Q99808,Q9UNN8,Q13572,Q9H4A3,P07741,P17612,P15531,P06744,P11172,P53621,Q86YV9,P04792,O00203,Q9UNS2 20 +Lipid localization 0.2984637196206277 1.1668523806145887 0.2432699893298808 1.0 0.6809493714066135 83 O15260,O43772,P35790,Q99720 4 +Peptidyl proline modification 0.3347680746978216 1.165624405981162 0.2437663357579702 1.0 0.6814706044599406 36 Q96AY3,P62942,Q5T1M5,Q13526 4 +Positive regulation of cell adhesion 0.3012494735346464 1.1648386206376795 0.2440843226214104 1.0 0.6816020985422938 62 P09429,Q13630,Q00534,P00491,P46109,O95999,P49841,P04083,Q96AC1,Q12955,Q06124,O00203,O14617,Q13043,Q9NUQ9,P46108,P23396,O95429 18 +Amino sugar metabolic process 0.5083303088990266 1.164486365738525 0.244226965527442 1.0 0.6816020985422938 8 P46926,Q06210,Q9UJ70,Q9Y223,O60502 5 +Negative regulation of axonogenesis 0.575819433125531 1.1619294172883736 0.2452641366991086 1.0 0.6826124492626792 6 Q8N0X7,Q9P265 2 +Tumor necrosis factor superfamily cytokine production 0.4030341351970781 1.161716262314061 0.2453507377519104 1.0 0.6826124492626792 21 P09429,Q13546,O95999,P14174,P04792,Q06124,Q9UPY3,O43823,P30046 9 +Ribosome associated ubiquitin dependent protein catabolic process 0.6196037521091573 1.161231548502552 0.2455477481425498 1.0 0.6826124492626792 5 Q9H1I8,Q8N3C0 2 +Negative regulation of t cell receptor signaling pathway 0.7752776154295666 1.1600488753944995 0.2460289074029598 1.0 0.6826124492626792 3 P15311,P51452 2 +Negative regulation of antigen receptor mediated signaling pathway 0.7752776154295666 1.1600488753944995 0.2460289074029598 1.0 0.6826124492626792 3 P15311,P51452 2 +Innate immune response activating signal transduction 0.6510428900257849 1.1594314579280511 0.2462803602355925 1.0 0.6826124492626792 4 Q16512 1 +Response to lectin 0.6510428900257849 1.1594314579280511 0.2462803602355925 1.0 0.6826124492626792 4 Q16512 1 +Purine nucleoside triphosphate catabolic process 0.7671633070406118 1.1592620998376657 0.2463493654120014 1.0 0.6826124492626792 2 Q9Y3Z3 1 +Regulation of lymphocyte differentiation 0.4204491138426927 1.1584275078311357 0.2466896189392535 1.0 0.6827185955876387 16 P09429,O00203,P04083,O15347 4 +Exonucleolytic catabolism of deadenylated mrna 0.4821329593059336 1.158157027608888 0.2467999612158009 1.0 0.6827185955876387 10 Q96C86,Q969T7 2 +Carbohydrate derivative catabolic process 0.3376216195422694 1.1574515718473135 0.2470879142296418 1.0 0.6827185955876387 33 Q9H773,Q13126,P15586,O60502 4 +Non motile cilium assembly 0.4728521927218186 1.1571374339653413 0.2472162147554146 1.0 0.6827185955876387 11 Q15691,Q15555,P27695,Q9UHD8,P27816,Q14203 6 +Carbohydrate metabolic process 0.261239531328261 1.1565635615188583 0.2474507167908841 1.0 0.6828720674484149 154 Q9BYT8,P48735,O75874,Q96E52,Q16539,P85037,O43813,Q13572,P46976,Q9UNI6,P06744,O43505,P06737,P34949,P37837,Q01968,P17174,O14874,P13807,Q13614,Q9UJ70,Q9Y223,Q9UKK9,Q04760 24 +Protein targeting to vacuole 0.4168797606401443 1.1557705392693398 0.2477750264542919 1.0 0.6834029181534278 17 Q9UN37,Q8IWJ2,Q96RL7,O00203,P46934,O14617,P20645 7 +T helper 1 cell differentiation 0.7738164815897366 1.154392356260907 0.2483393475162687 1.0 0.6843207290779308 3 P09429,P04083 2 +T helper 1 type immune response 0.7738164815897366 1.154392356260907 0.2483393475162687 1.0 0.6843207290779308 3 P09429,P04083 2 +Xmp metabolic process 0.539560864993807 1.152381433530419 0.2491643670010375 1.0 0.6856590159588491 7 P12268,P22102,Q06203,P22234,P31939 5 +Immunoglobulin production 0.3767509569137803 1.152253103888122 0.2492170816500913 1.0 0.6856590159588491 26 Q9UQ84,Q16512,O96028,P13051 4 +Negative regulation of establishment of protein localization to mitochondrion 0.6489878282153176 1.1507447206225652 0.2498372726388251 1.0 0.6868305502781291 4 O95429,O95817 2 +Extracellular matrix assembly 0.6172002760504708 1.1507106751315983 0.2498512833080937 1.0 0.6868305502781291 5 O75122,Q96AY3 2 +Peptidyl tyrosine modification 0.3216388326419249 1.149715123656012 0.2502612232370276 1.0 0.6870649136942492 43 Q02750,P30153,Q9H2J4,P42345,P36507,Q13177,P33981,Q06124,Q9UNH7,P14174,Q96KB5 11 +Positive regulation of protein kinase a signaling 0.7645340344726888 1.1483743677945373 0.2508140504878067 1.0 0.6870649136942492 2 P14174 1 +Positive regulation of cytokine production 0.3023525696962198 1.1475128673039652 0.2511697182376293 1.0 0.6871261474166516 60 P09429,Q16539,Q99497,Q13546,P00491,O95999,P04083,Q9NUD5,P04792,Q06124,Q13283,Q9NUQ9,P14174,P23396,O60684,P30046 16 +Lysosomal transport 0.3137133184620091 1.143536722658379 0.2528158168205499 1.0 0.6907511828709381 48 Q9UN37,Q9NZZ3,Q86VS8,Q9UID3,O00203,P46934,P20645,Q8WUH2,Q9HD42 9 +Regulation of polysaccharide metabolic process 0.5376927497548187 1.1432035489905632 0.2529540891156621 1.0 0.6907511828709381 7 P49841 1 +Regulation of cell shape 0.3440024061770413 1.1427427270283148 0.2531454242694804 1.0 0.6909874272399232 31 P04083,Q9UEE9,Q9UIW2,Q9UQB8,P46108 5 +Antigen processing and presentation of exogenous antigen 0.5040037163760507 1.1419158850808016 0.253488985068844 1.0 0.6914061087581244 8 P04439,O00203,Q06323,O14617 4 +Regulation of actin filament organization 0.2923510941271807 1.141261448226894 0.2537611399748734 1.0 0.6914061087581244 68 O15144,P47755,P42345,P35080,P16949,Q16512,O95429,Q9Y281,Q96AC1,P07737,Q9UQB8,O60504,O15145,O75116,Q13177,Q9BPX3,P60983,P35241,Q14019,Q9NUQ9,Q13045,P60981,Q9UEY8,P62330,Q6IBS0,O75122,Q9UHB6,Q7Z460 28 +Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity 0.7627811860940839 1.141121546888937 0.2538193458953428 1.0 0.6914061087581244 2 P42858 1 +Synaptic vesicle exocytosis 0.4112105513262227 1.1405124350423117 0.2540728750577825 1.0 0.6915040825209824 18 P49841,Q4J6C6,P35080,Q15042,P0DP25,O95721 6 +Sterol metabolic process 0.3242090340042669 1.139537965745607 0.2544788424908153 1.0 0.6915040825209824 41 Q15125,Q9UBM7,P34913,Q16850 4 +Negative regulation of cell adhesion 0.3289169225068851 1.1382572564481948 0.2550130765870799 1.0 0.6919265070973553 38 P09429,Q9Y5A9,Q9H4A3,P04083,P42771,Q9H6U6,Q06124,Q9UIW2,Q9P258,P51452,Q96J02,O75122 12 +Dendrite morphogenesis 0.3342595862751877 1.1378840736239486 0.2551688924080204 1.0 0.6919265070973553 34 Q6SZW1,Q9UQB8,P49841,Q00535,Q96HC4,Q9Y4F1,O43251,O60678,P46934,Q96PU5 10 +Regulation of microtubule polymerization or depolymerization 0.3341944833021115 1.1373023184270448 0.255411925896629 1.0 0.6920162003742615 34 P46821,Q15691,Q15555,P36405,P23396,Q14203,O75122,P78559,P16949,Q16512,Q7Z460,P04350 12 +Regulation of microtubule cytoskeleton organization 0.303598688088036 1.134437511790396 0.2566110715777929 1.0 0.6944089424633872 58 P46821,Q15691,Q15555,P49841,O75351,Q9NZZ3,P23396,Q8TD16,P43034,Q14203,O75122,P78559,P16949,Q16512,Q9HD42 15 +Negative regulation of cellular amide metabolic process 0.2940763835164922 1.133348898339413 0.2570677647927297 1.0 0.6950741203911708 94 P00374,Q96C86,P51114,Q5TAX3,Q9HCE1,Q969T7,Q14011,Q9Y6M1,Q13526,P67809 10 +Positive regulation of glucose import 0.6131602019676365 1.1330357614430653 0.2571992358438355 1.0 0.6951444701445526 5 Q16539,Q06124 2 +Axon extension 0.3489407960984792 1.1277267817213965 0.2594353234579998 1.0 0.698351647934677 30 P46821,P08238,Q9UL25,P49841,P18206,Q93008,P43034,Q14247,Q9P265,P78344,Q6IBS0,Q16555,Q13740,P07900,Q00535 15 +Regulation of defense response 0.2928955991192682 1.1274974898697665 0.2595322011946859 1.0 0.698351647934677 96 Q99497,P98170,Q06124,P28070,Q96J02,P46108,Q16512,P30046,P09429,Q16539,P19474,P04083,Q9Y3Z3,Q16543,Q9NUD5,P60900,Q53EL6,Q9UNH7,Q96KB5,P08238,P39019,Q13177,Q13546,Q8TDB6,Q92879,Q9Y5A9,Q9BXW9,Q7Z739,P25786 29 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.6434732439520415 1.1274525204239711 0.2595512041019354 1.0 0.698351647934677 4 O75832 1 +Lymphocyte mediated immunity 0.3305330830566155 1.1270762626988338 0.2597102384958076 1.0 0.6984944480474762 36 P09429,Q96FZ2,O95999,Q9UQ84,O96028,Q9NUQ9,P07437,P46108,P13051 9 +Positive regulation of lipid kinase activity 0.6112930449222556 1.1248717891873616 0.2606433679457101 1.0 0.7003127010953545 5 Q05639 1 +Regulation of hematopoietic stem cell proliferation 0.758691206543969 1.12421682205566 0.2609210547174765 1.0 0.7003223097302953 2 O95251 1 +Protein localization to ciliary membrane 0.611058384661341 1.1238459816112407 0.2610783708327113 1.0 0.7004593490147469 5 Q9UJY5,Q9UPT5 2 +Regulation of cell communication by electrical coupling involved in cardiac conduction 0.7581069237511115 1.1218040571224448 0.2619457608300783 1.0 0.7006384265563932 2 P0DP25 1 +Sequestering of metal ion 0.758106923751106 1.121804057122422 0.2619457608300881 1.0 0.7006384265563932 2 O14617 1 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.6105645399091806 1.121687326983338 0.2619954067751076 1.0 0.7006384265563932 5 P98170 1 +Immune response regulating signaling pathway 0.298697497124144 1.120811749528953 0.2623680017638354 1.0 0.7010660184950156 61 P98170,Q14232,P15311,Q96J02,P51617,Q16512,P09429,Q6SZW1,Q9H4A3,Q9NR50,Q9NUD5,P23396,P46109,O00203,Q01804,P49770,O95999,Q13144,P51452 19 +Vacuolar transport 0.3008738675040497 1.1173467666472572 0.2638460866779701 1.0 0.7033050559568053 59 Q9UN37,Q9NZZ3,Q96RL7,Q86VS8,Q9UID3,O00203,Q92783,P46934,P20645,Q8WUH2,Q9HD42 11 +Replicative senescence 0.6406919593241438 1.1157160560409984 0.2645436955789773 1.0 0.7045947641440882 4 Q13535 1 +Positive regulation of stress fiber assembly 0.4460393357096003 1.1154457205053836 0.2646594663588872 1.0 0.7046184177050827 13 Q96AC1,O60504,Q16512,P35080 4 +Protein k29 linked ubiquitination 0.7635885447107085 1.1148616382245864 0.2649097179187007 1.0 0.704999943689978 3 Q96J02,Q15386 2 +Phosphatidylinositol 3 phosphate biosynthetic process 0.6400421494975209 1.1129751403052657 0.2657191064237842 1.0 0.7051171403103338 4 Q01968,Q8NEB9 2 +Transforming growth factor beta receptor signaling pathway 0.3598086582757311 1.112925778453114 0.2657403076111322 1.0 0.7051171403103338 28 Q96AC1,P62942,Q8WUH2,Q13526 4 +Middle ear morphogenesis 0.6400150883742511 1.1128610054992474 0.2657681297185097 1.0 0.7051171403103338 4 O95747,P54802 2 +Pancreatic juice secretion 0.755769792579617 1.112158705042907 0.2660699195570184 1.0 0.7051171403103338 2 Q9H4A3 1 +Oogenesis 0.4031622730031187 1.1102468927943367 0.2668926509281608 1.0 0.7061310687118543 19 Q9Y5A9,P30153,Q15645,Q5TAX3,Q8N2A8,Q9BQA1,O14965 7 +Cytoplasmic translational initiation 0.3914839440982994 1.1100579923167384 0.2669740374538849 1.0 0.7061310687118543 22 O15371,P23588,Q14152,Q9Y5A9,P42345,P20042,Q9NR50,Q14240,Q15056,Q9ULC4,Q04637,P55010,P60842 13 +Modulation of excitatory postsynaptic potential 0.6075801672672279 1.108647294361823 0.267582367082404 1.0 0.7068590985645357 5 Q9UQB8 1 +Protein localization to cell surface 0.4028870657823734 1.1084009402582642 0.2676886990249887 1.0 0.7068590985645357 19 Q9UJY5,Q9HD26,P08238,Q13107,O00203,Q9H490,P78559,Q96PU5 8 +Somatic diversification of immunoglobulins 0.3989419799146029 1.1065611770739658 0.2684837002613167 1.0 0.7081850940328936 20 Q9UQ84,O96028 2 +Cellular senescence 0.3909553628471127 1.1063444068504231 0.2685774780161156 1.0 0.7081850940328936 22 P42771,Q16539,P67809,Q00534 4 +Negative regulation of intracellular transport 0.4024244827841888 1.105298536547284 0.2690302518498992 1.0 0.7082457748380735 19 P46821,Q99497,O95817,Q9UHD1,O95429,Q00535 6 +Mitotic cell cycle phase transition 0.250108629836184 1.1009811365279747 0.2709048671030369 1.0 0.7109095875570142 141 Q93034,Q9UN37,O43768,O75351,P33981,O00716,P42771,P15927,P24941,P49321,Q99640,Q96K76,Q00534,Q15645,P04083,Q16763,Q9NWV8,Q14674,Q9P258,Q9Y6G9,O60921,Q86Y37,Q07864,P31350,O43670,Q969U7,P83731,Q04637,P61289,Q9NZJ0,Q9UL46,Q00535,P49427,O95905,Q9UPP1,Q96DY7,O95067,Q13309,O75122,O14965,Q6UVJ0,P0DP25,Q7Z460 43 +Amino sugar biosynthetic process 0.6368274376835931 1.0994222022529567 0.2715839508928597 1.0 0.711993839353957 4 Q06210,Q9Y223 2 +Udp n acetylglucosamine metabolic process 0.6368274376835931 1.0994222022529567 0.2715839508928597 1.0 0.711993839353957 4 Q06210,Q9Y223 2 +Dna dealkylation 0.4957650676739199 1.098977558057881 0.2717778548289287 1.0 0.711993839353957 8 Q01804,Q8N3C0,P27695,Q93008 4 +Nucleotide salvage 0.5621526762211201 1.0985642676825944 0.2719581707308114 1.0 0.711993839353957 6 P55263,P00492,P07741,Q01433,Q9BZX2 5 +Spindle assembly involved in female meiosis 0.7592560311307035 1.098154468094799 0.2721370444769637 1.0 0.7121585538674653 3 O95067 1 +Peripheral nervous system development 0.4532232411023676 1.0976693727605946 0.2723488881886666 1.0 0.7121800113044078 12 Q9UPY3,P21266,Q00535,P31751 4 +Skeletal muscle organ development 0.3578830689665301 1.097640918000889 0.2723613180367736 1.0 0.7121800113044078 28 Q9BYT8,Q16539,P16989,P51114,P61201,O94966 6 +Positive regulation of muscle cell apoptotic process 0.4796266235545463 1.096245464328204 0.2729713682901189 1.0 0.7132093776331605 9 P42771,Q53EL6,Q9NQ88 3 +Pigmentation 0.4043988368973534 1.0954611584485583 0.2733146531196393 1.0 0.7133298049023371 18 Q9H267,Q86YV9,Q92995,O00203,Q9BXS5,O14617 6 +Negative regulation of defense response 0.3242715317577774 1.0952394465460604 0.2734117482582032 1.0 0.7133298049023371 38 Q16539,P19474,P28070,P46108,Q96KB5 5 +Regulation of cell communication by electrical coupling 0.7583284628872144 1.0945807616617864 0.2737003477341475 1.0 0.7133298049023371 3 Q12955,P0DP25 2 +Positive regulation of protein dephosphorylation 0.4212164555894718 1.093396850531829 0.2742195957587321 1.0 0.7138945483249005 15 P08238,Q15257,Q8IV63,P0DP25,Q14738,Q13526,Q15435 7 +Response to l glutamate 0.6038750433512431 1.0924708790441438 0.2746261835528016 1.0 0.7138945483249005 5 Q9UQB8 1 +Positive regulation of intracellular protein transport 0.2973646642724756 1.0917651922745393 0.2749363221295537 1.0 0.7139922882407347 60 O94766,Q9UBE0,Q12955,P62826,Q16539,Q9Y282,Q9H6U6,Q14012,P17612,Q92688,P08238,P31751,P49841,O95817,O14737,P68036,Q13263,Q9UHD1,Q7Z6Z7,P62258,Q00535,Q9NR31,Q9Y3D6,P19784,Q9C0E2,Q9Y4C2,P06493 27 +Translational elongation 0.3570335678044336 1.0909023859161486 0.2753158371659472 1.0 0.7139922882407347 28 P24534,P26641,P05387,P05386,P29692,P13639,Q8N3C0,Q9Y450,Q9BQC3,Q9H1I8,Q9BTV6,Q86UK7,P63241,Q05639 14 +Cell cycle dna replication initiation 0.5603977771278201 1.0904402191453963 0.2755192733788343 1.0 0.7139922882407347 6 P33993,P49736,Q9BRX5,P25205,P33991 5 +Negative regulation of chemotaxis 0.5600978667748409 1.0890521694458657 0.2761308805660141 1.0 0.7141738736835807 6 P51452,P30046 2 +Polyol metabolic process 0.3841682780452887 1.0884757703368453 0.2763851273732349 1.0 0.7142025714011622 23 Q13614,P00374,P35270,Q01968,P17174 5 +Synaptic vesicle recycling 0.4058212668315536 1.083643332467933 0.2785229700434546 1.0 0.7166252780740606 17 Q99961,Q9Y263,P50570,O00203,P62330,P0DP25,O14617,Q00535 8 +Positive regulation of apoptotic signaling pathway 0.3292128989859338 1.083040163333388 0.2787905963488173 1.0 0.7166252780740606 33 P62081,Q99497,P30154,P30153,O95999,Q13177,Q13043,P63241,P23396,Q13546,Q9UNN5 11 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3301647417841526 1.0824036901105016 0.2790731893241798 1.0 0.7166252780740606 32 P62942,P98170,P33981,Q13526,Q93062,Q8N0X7 6 +Negative regulation of neuron death 0.3145771967496779 1.080918443565338 0.279733393663649 1.0 0.7174038266269575 43 P06744,P08238,Q01105,Q99497,P51858,P49841,Q9UMX5,P07196,Q9UNH7,Q9NQ88,Q00535 11 +Positive regulation of cellular response to insulin stimulus 0.5242621566525327 1.0773098846130678 0.2813418478056282 1.0 0.7194044499951457 7 Q9Y5X3,Q9H1E3 2 +Positive regulation of dephosphorylation 0.4078413262489722 1.0773033590272223 0.2813447621491938 1.0 0.7194044499951457 16 P08238,Q15257,Q8IV63,P0DP25,Q14738,Q13526,Q15435 7 +Protein localization to axon 0.7537102056722627 1.076805506847546 0.2815671646324995 1.0 0.7194925693424734 3 Q12955 1 +Positive regulation of cell substrate junction organization 0.4665581270023071 1.0727252413798114 0.2833944117048927 1.0 0.7207631333467218 10 P51452,Q15555 2 +Regulation of calcium mediated signaling 0.4907209999060752 1.07272432541961 0.2833948227949601 1.0 0.7207631333467218 8 P49841,P0DP25,Q9UHD1,P42858 4 +Photoreceptor cell maintenance 0.7522692330159065 1.0712656490432944 0.2840500006585187 1.0 0.7212856719341122 3 Q15051 1 +Photoreceptor cell development 0.5989512443356109 1.0709984881874148 0.2841701094138844 1.0 0.7213128075688587 5 P36405,Q15555 2 +Spindle assembly 0.2951527108056692 1.067109272110166 0.2859224953524699 1.0 0.7243662910697471 60 Q15018,Q15691,Q15555,O43670,O75351,Q9H6D7,Q9NZZ3,Q9P287,O95067,O75122,P23396,Q9HD42,Q96CS2 13 +Cellular response to aldehyde 0.5548710342334491 1.0648785920954384 0.2869308738798077 1.0 0.7257468797878891 6 Q8TC12,P10768,Q99497,O95831 4 +Regulation of nervous system development 0.2872929354230741 1.0635120693743036 0.2875497947559164 1.0 0.7257468797878891 71 P42345,Q9UPY3,Q96P11,Q02750,P55209,P27695,Q86VS8,Q96G23,P13010,Q9UQB8,P53990,O43379,Q16706,Q00535,P46821,Q13614,Q9Y5A9,Q04917,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q8N0X7 24 +Morphogenesis of an epithelial sheet 0.4887956263001332 1.062712051294268 0.2879125539916876 1.0 0.7257468797878891 8 Q96AC1,O75122,Q7Z460 3 +In utero embryonic development 0.2871547313284914 1.0623069077630758 0.2880963794761477 1.0 0.7257468797878891 98 P06744,O43772,Q96AY3,P55199,P16989,Q9BRT9,Q9UNS2,Q92541,Q6DKJ4,P20290,O95067,Q96EK5,P49321,Q01968,P67809 15 +Extracellular exosome assembly 0.6278774717022594 1.061756354705618 0.2883463083538269 1.0 0.725765125875688 4 Q92783,O00560 2 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.7495616598480492 1.0608648299552297 0.2887513345570769 1.0 0.7265071745802485 3 O60678,Q86X55 2 +Trna 5 leader removal 0.6273605131050555 1.059584034576007 0.2893338800526617 1.0 0.7270018367824604 4 Q99575,P05455 2 +Positive regulation of exosomal secretion 0.4880172834856547 1.0586660699833264 0.2897518855288044 1.0 0.7270018367824604 8 Q9UN37,O14964,O75351,Q92783,O00560 5 +Negative regulation of dendrite development 0.7426234297400114 1.058089238187774 0.2900147602906835 1.0 0.7270018367824604 2 Q86X55 1 +Response to epidermal growth factor 0.4045555048432193 1.056211337142627 0.2908716723219566 1.0 0.7271240288002799 16 Q9UQB8,Q06124,P51452,O95429 4 +Mirna metabolic process 0.4717364593634005 1.0538293499174312 0.2919610535118282 1.0 0.7284660351059696 9 Q5TAX3,Q9UPY3 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.4040972845187235 1.053272091096657 0.2922163061747755 1.0 0.7285941802511717 16 P31350,P04083,P27695,Q96DY7,Q04637,P35241,Q6UVJ0,P23921 8 +Regulation of fat cell differentiation 0.4453353356941287 1.052778921562963 0.2924423277107442 1.0 0.7285941802511717 12 Q16539,Q96A49,Q96AC1,Q86X55,Q13043 5 +Cilium organization 0.2938514216310912 1.0526262600065937 0.2925123168933889 1.0 0.7285941802511717 60 Q15691,Q9NVG8,Q4KMP7,Q14203,Q9Y496,P27695,A0AVF1,Q15019,P42858,O95721,P49841,Q01968,Q8IVD9,Q9NT62,A6NIH7,Q15555,Q8TC07,Q86Y56,Q66K14,Q15051 20 +Epiboly 0.5191472978488656 1.0522702544189608 0.2926755748339051 1.0 0.7285941802511717 7 Q96AC1,O75122,Q7Z460 3 +Late endosome to golgi transport 0.7466393921683262 1.049652237875129 0.2938780305472304 1.0 0.7302088116725755 3 Q8IWJ2,O60493 2 +Water homeostasis 0.4708762998594006 1.0492108972434424 0.2940810643183558 1.0 0.7303652756583486 9 Q96PU5 1 +B cell mediated immunity 0.3937446709389873 1.0471860163941584 0.2950137934134522 1.0 0.7312011049093751 19 Q9UQ84,O96028 2 +Positive regulation of transporter activity 0.3900340807724633 1.046028240601549 0.2955479940195711 1.0 0.7321504609458898 20 P42858,Q9H4A3,P28161,Q12955,Q9UHD1,P0DP25,Q00535 7 +Positive regulation of tau protein kinase activity 0.7391177329827655 1.0437293912102186 0.2966106076163539 1.0 0.7334047732209322 2 P08238 1 +Positive regulation of response to wounding 0.4692740661743717 1.040611379764259 0.2980559475868709 1.0 0.735859021723049 9 P04083 1 +Response to interleukin 1 0.39605387186948 1.040414291184646 0.298147464924579 1.0 0.735859021723049 18 Q01804,P04083 2 +Cellular metabolic compound salvage 0.4516066402870535 1.038454765137985 0.2990583843992458 1.0 0.735859021723049 11 O00764,P00491,P55263,Q13126,Q9BV20,P00492,P07741,Q01433 8 +Regulation of synaptic vesicle recycling 0.5481134834747092 1.0336806694405916 0.3012854729123795 1.0 0.735859021723049 6 Q7L576,Q9Y263,Q13464,P0DP25,Q00535 5 +N acetylneuraminate catabolic process 0.7364884604148525 1.032977305738746 0.3016145191778157 1.0 0.735859021723049 2 Q9UJ70 1 +Amino sugar catabolic process 0.7364884604148525 1.032977305738746 0.3016145191778157 1.0 0.735859021723049 2 Q9UJ70 1 +Filopodium assembly 0.4113713196464902 1.0322000037627763 0.3019784332965987 1.0 0.735859021723049 15 Q16658,O14786,P51114,Q9NUL3,Q9H6U6,P15311,P62330,Q14195,P47756,P11233,Q06787 11 +Regulation of glucose metabolic process 0.3604615839280082 1.0287235260031815 0.3036096115315811 1.0 0.735859021723049 26 Q9BYT8,Q9UNI6,P85037,O14874,P49841,A6NDG6,Q13043,Q9NQ88 8 +Purine deoxyribonucleoside triphosphate metabolic process 0.7353198948291038 1.0282036697867671 0.3038540325511429 1.0 0.735859021723049 2 Q9Y3Z3 1 +Purine deoxyribonucleoside monophosphate metabolic process 0.7353198948291022 1.0282036697867596 0.3038540325511465 1.0 0.735859021723049 2 P00491 1 +Damp metabolic process 0.7353198948291022 1.0282036697867596 0.3038540325511465 1.0 0.735859021723049 2 P00491 1 +Negative regulation of protein dephosphorylation 0.4308550350222028 1.0265524284524905 0.3046312641963373 1.0 0.7363255933338739 13 Q15257,P17931,P62942,P49841,O43768,O75116,P31946 7 +Cartilage development 0.4103356422044755 1.025776609278122 0.3049968939828087 1.0 0.7363255933338739 15 Q16539,Q96AQ6,Q9C0E8,O95747 4 +Regulation of gtpase activity 0.2831600461090588 1.025604567114792 0.3050780138285698 1.0 0.7363255933338739 69 P42345,Q9NVG8,Q13526,P46108,P16949,Q86YR5,Q8WU90,Q9H4A3,Q96HP0,Q96AC1,Q9H6U6,Q9P258,Q96AQ6,P46109,P31751,P49841,O60343,Q01968,Q15042,Q15555,Q8TC07,P43034,Q9UIW2,Q66K14 24 +Mitotic cytokinesis 0.3180627715344177 1.025575508622063 0.3050917166529909 1.0 0.7363255933338739 37 Q9UN37,Q6DKK2,Q9NZZ3,Q14674,P16949,Q9HD42 6 +Negative regulation of protein polymerization 0.3427124091636712 1.0247118599262477 0.3054991653167695 1.0 0.7363255933338739 29 P58546,Q15691,Q13045,P47755,Q9BPX3,Q9UEY8,P07737,P35241,P35080,Q9NUQ9,Q02790,Q6IBS0,P16949,Q9BTW9,Q12792,P04350 16 +Defense response to fungus 0.5460569852501733 1.0242003764909984 0.3057406409762326 1.0 0.7365311881771337 6 P81605 1 +Carbohydrate phosphorylation 0.513326078165137 1.02382136068563 0.3059196591670194 1.0 0.7365311881771337 7 P51570,Q9Y223,Q9UJ70,Q13572 4 +Biological process involved in interaction with symbiont 0.3483991113258681 1.0226003412176097 0.3064968482112489 1.0 0.7369969254200929 28 P81605,Q9H1E3 2 +Photoreceptor cell differentiation 0.5456756238240347 1.0224431108466625 0.3065712251081463 1.0 0.7369969254200929 6 P36405,Q15555 2 +Activated t cell proliferation 0.5129303716088157 1.0218896092170882 0.3068331509219928 1.0 0.7369969254200929 7 P09429 1 +Cell proliferation involved in kidney development 0.7335670464504936 1.021049217093975 0.307231121215779 1.0 0.7369969254200929 2 O95747 1 +Cell proliferation involved in metanephros development 0.7335670464504936 1.021049217093975 0.307231121215779 1.0 0.7369969254200929 2 O95747 1 +Mesenchymal cell differentiation involved in kidney development 0.7335670464504936 1.021049217093975 0.307231121215779 1.0 0.7369969254200929 2 O95747 1 +Negative regulation of kidney development 0.7335670464504936 1.021049217093975 0.307231121215779 1.0 0.7369969254200929 2 O95747 1 +Metanephric mesenchymal cell differentiation 0.7335670464504936 1.021049217093975 0.307231121215779 1.0 0.7369969254200929 2 O95747 1 +Schwann cell differentiation 0.465567425122436 1.0207350690649133 0.3073799747109844 1.0 0.7370008200530794 9 Q9UPY3,Q00535,P31751 3 +Negative regulation of necrotic cell death 0.5873036584810186 1.0203380748462318 0.3075681516938746 1.0 0.7370008200530794 5 P16989 1 +Negative regulation of programmed necrotic cell death 0.5873036584810186 1.0203380748462318 0.3075681516938746 1.0 0.7370008200530794 5 P16989 1 +Regulation of endothelial cell migration 0.3218387295440116 1.0181029308004224 0.3086290426871674 1.0 0.7384497714687002 33 P09429,Q16539,P04083,P42785,P04792 5 +Response to food 0.5120683764866012 1.0176825328373964 0.3088288508328456 1.0 0.7384497714687002 7 Q9UMX5,P80303 2 +Negative regulation of response to cytokine stimulus 0.4478671841216795 1.0176486329346557 0.3088449666169912 1.0 0.7384497714687002 11 Q01804,Q7Z739,Q9Y3Z3,P98170 4 +Negative regulation of dna binding transcription factor activity 0.3417672188905071 1.0170809319463194 0.3091149304366278 1.0 0.7388244159147173 29 P19474,P42771,O75832,Q96J02,Q9UHD1,P51617,O00221,Q9UNN5 8 +Regulation of biological process involved in symbiotic interaction 0.47991572893402 1.0166123167743366 0.3093378925856522 1.0 0.7388244159147173 8 P19474,Q9UPT5,Q14258,O60493,Q12899 5 +Actin polymerization or depolymerization 0.296598630735323 1.0148419816353975 0.3101811581930178 1.0 0.7403020256366305 54 O15144,P47755,P42345,O60610,P35080,O95429,Q12792,P57737,Q9Y281,P07737,Q9UQB8,O15145,Q9BPX3,P23528,P35241,Q14019,Q9NUQ9,Q8N8S7,Q13045,P58546,P60981,Q9UEY8,P62330,Q14247,Q6IBS0,Q9UHB6 26 +Hepatocyte apoptotic process 0.6164864074831992 1.013986408425706 0.3105892377849721 1.0 0.7403870190051017 4 P62330,Q13131,Q13043 3 +Schwann cell development 0.4793373033545899 1.0136144377709135 0.3107667657178345 1.0 0.7403870190051017 8 Q9UPY3,Q00535 2 +Regulation of non motile cilium assembly 0.543602482690743 1.0128947710571787 0.3111104262718076 1.0 0.7409103793293916 6 Q9UHD8,P27695,Q15555,P27816 4 +Positive regulation of gtpase activity 0.3037456419791726 1.0111360029671903 0.3119513407572261 1.0 0.7414331846626065 45 Q8WU90,Q15555,P46109,P49841,Q8TC07,Q9NVG8,Q96HP0,Q96AC1,Q9H6U6,Q66K14,Q9P258,Q13526,O60343,P46108,Q15042 15 +Pigment granule maturation 0.736354289647023 1.0103048358246338 0.3123492650124873 1.0 0.7414889003748291 3 O14617 1 +Pigment accumulation 0.736354289647023 1.0103048358246338 0.3123492650124873 1.0 0.7414889003748291 3 O14617 1 +Membrane depolarization 0.4462713968379839 1.0087800096001394 0.3130801502320086 1.0 0.7414889003748291 11 Q12955,Q99497,Q96PU5 3 +Female gamete generation 0.3466221854657254 1.008593863334926 0.3131694515919148 1.0 0.7414889003748291 28 Q9Y5A9,P30153,Q15645,Q5TAX3,Q8N2A8,Q93008,P33981,O95067,Q9BQA1,O14965,O60879 11 +Exit from mitosis 0.4547076738517651 1.0079684240537596 0.3134696211378038 1.0 0.7414889003748291 10 O75122,Q7Z460,P83731 3 +Purine deoxyribonucleotide metabolic process 0.7355347749853942 1.0071779680269095 0.3138492586199992 1.0 0.7414889003748291 3 P00491,Q9Y3Z3 2 +Viral gene expression 0.3133128734222924 1.007150664529212 0.3138623772516367 1.0 0.7414889003748291 39 O75821,O15371,P48729,P19474,O14646,Q14152,P49841,Q9Y262,Q9ULC4,P55884,Q9H1E3,Q16706,P17980,Q99873,Q4G0J3,P05455 16 +Positive regulation of nik nf kappab signaling 0.4372204975364629 1.0067404330005278 0.3140595264280366 1.0 0.7414889003748291 12 Q53EL6,Q9NYB0 2 +Pre mirna processing 0.5841655479535066 1.0067266361741103 0.3140661583260415 1.0 0.7414889003748291 5 Q5TAX3 1 +Positive regulation of wnt signaling pathway 0.3805141777984613 1.0062862126967935 0.3142779107474625 1.0 0.7414889003748291 21 Q96AQ6,P98170,Q9H4A3,P40818,Q13526 5 +Regulation of amyloid fibril formation 0.5094667356916086 1.0049934389897153 0.3149000091403038 1.0 0.7424252003765675 7 Q9UHV9,Q9NQP4,O15212,Q99471 4 +Establishment or maintenance of monopolar cell polarity 0.4539346338763931 1.0037545001912285 0.3154969604770219 1.0 0.7428625119854925 10 P46821,Q16658,P26038,P15311,Q92538,P60953,O14745 7 +Fructose 1 6 bisphosphate metabolic process 0.5413327012230433 1.0024496882901195 0.3161264542203665 1.0 0.7437207659602628 6 Q01813,P08237,Q9NQ88 3 +Tyrosine metabolic process 0.7333287459109468 0.9987673388072792 0.3179074113698918 1.0 0.7471107507131292 3 P16930 1 +Response to temperature stimulus 0.2945823714967813 0.993557419822446 0.3204383828200057 1.0 0.751451376573987 54 Q14232,Q99543,P42345,P25685,P51617,Q9NR50,Q14011,Q13535,P31689,P17612,P08238,P49841,Q99615,O95817,Q9UHD1,P49770,Q9UER7,O60884,Q13144,O75190 20 +Voluntary musculoskeletal movement 0.6109049130952084 0.990662204283406 0.3218505524447659 1.0 0.7524869712253621 4 P78559 1 +Platelet activation 0.4147835292173233 0.9906091819451496 0.3218764524303059 1.0 0.7524869712253621 14 Q16539 1 +Protein peptidyl prolyl isomerization 0.3442855076263594 0.9902053177613134 0.3220737738615513 1.0 0.7524869712253621 28 Q96AY3,P62942,Q5T1M5 3 +Regulation of protein localization to cell surface 0.4511649042370391 0.9886685991213136 0.3228253109547077 1.0 0.7524869712253621 10 P08238,Q9HD26,Q96PU5,P78559 4 +Thyroid hormone mediated signaling pathway 0.7253870873502944 0.9877619554829686 0.3232692438440248 1.0 0.7524869712253621 2 P42785 1 +Trna pseudouridine synthesis 0.7250949459538433 0.9865763186170828 0.3238503843382125 1.0 0.7524869712253621 2 Q96PZ0 1 +Regulation of protein serine threonine kinase activity 0.2807707846212766 0.98565928881987 0.3243003334317742 1.0 0.7524869712253621 71 Q96A49,P36507,P42771,Q13043,P51617,Q16512,Q02750,Q16543,Q96AC1,P31689,Q53EL6,Q14012,Q9Y4R8,P23396,P14174,P42858,O95373,O75832,Q9UHD1,Q96SZ6,Q9P287,O95067,P0DP25 23 +Regulation of cytoplasmic translation 0.3907091219561617 0.9855582948358192 0.3243499119308459 1.0 0.7524869712253621 17 P67809 1 +Positive regulation of leukocyte proliferation 0.4037683484689237 0.9851235412440454 0.3245633911939523 1.0 0.7524869712253621 15 P09429,P14174,P23396,P04083 4 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3904747888539192 0.9840434888053404 0.3250941306159722 1.0 0.7524869712253621 17 P62942,Q8N0X7,Q13526 3 +Ribosome disassembly 0.578362573099406 0.9816050681107324 0.3262944497076656 1.0 0.7524869712253621 5 Q9BRX2,Q9ULC4,O43583,P46199 4 +Columnar cuboidal epithelial cell development 0.4729267535337371 0.9804377654983332 0.326870075648662 1.0 0.7524869712253621 8 P49841,Q00534 2 +Histone threonine phosphorylation 0.6084244234534554 0.9803162840279572 0.3269300190517956 1.0 0.7524869712253621 4 Q16512,Q9Y4B6 2 +Autophagosome maturation 0.3728746396240505 0.9799024773059948 0.3271342600086124 1.0 0.7525434433501369 22 Q9NZZ3,Q9HD42,Q13137,O95721 4 +Regulation of lymphocyte migration 0.4578510047614836 0.9794500249629328 0.3273576699323173 1.0 0.7525434433501369 9 O95747,P46108,P46109 3 +Negative regulation of guanyl nucleotide exchange factor activity 0.7282236715241188 0.9793416557387116 0.3274111947099807 1.0 0.7525434433501369 3 P16949 1 +Response to amino acid starvation 0.4493604541798386 0.978851093196821 0.3276535601255501 1.0 0.7528378113817852 10 P49327,Q9P2J5,Q6PKG0,Q9BY44,P42345,Q92616,P19525 7 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.440835317916035 0.9786201976499264 0.3277676757684653 1.0 0.7528378113817852 11 Q13546,P30154,P30153 3 +Positive regulation of jnk cascade 0.5038361009362818 0.9775785287171378 0.32828282102491 1.0 0.7532336777571204 7 P09429,P98170 2 +Regulation of pattern recognition receptor signaling pathway 0.3636542336327536 0.9764714531800616 0.3288308876700587 1.0 0.7533333895618407 24 P09429,Q6SZW1,Q01804,P98170 4 +Regulation of establishment of protein localization to mitochondrion 0.3892629447526524 0.9762133026276404 0.3289587724087188 1.0 0.7533333895618407 17 Q9UBE0,O95817,O14737,P31689,P68036,Q7Z6Z7,O95429 7 +Regulation of peptidyl serine phosphorylation 0.3586202281728393 0.9759214633014556 0.3291033849847591 1.0 0.7533333895618407 25 P08238,Q99497,Q9NYB0,P10398,Q13043,P35080,Q14012,P14174,Q16512,O95429 10 +Cell activation involved in immune response 0.3098431474625721 0.9750484313852732 0.3295362367470167 1.0 0.75378509563901 39 P09429,Q9UQ84,P04083,O96028,P13051 5 +Positive regulation of cellular amine metabolic process 0.6067706711943411 0.9734257398905364 0.3303417512105007 1.0 0.7548051382944959 4 Q6QHF9 1 +Regulation of mrna binding 0.5026566060341497 0.9718446338534218 0.3311278472266905 1.0 0.7560143211834424 7 Q86X55,O15371,Q04637 3 +Coronary vasculature development 0.5024939363008337 0.9710541018937132 0.3315213380686481 1.0 0.7562176015186733 7 Q15750,O95487,O14786,Q15036 4 +Negative regulation of dna templated transcription elongation 0.5023989861432752 0.9705926982779568 0.3317511434521329 1.0 0.7562176015186733 7 P18615,Q8IXH7,O00267,Q4G0J3,Q8WX92 5 +Polyol biosynthetic process 0.430821908681875 0.9705690177783746 0.3317629404720879 1.0 0.7562176015186733 12 P00374 1 +Regulation of response to interferon gamma 0.72559906487434 0.9693760363480116 0.3323576042393021 1.0 0.7570495256204146 3 P08238,Q16543 2 +Transport along microtubule 0.2904175215515822 0.9686225563045828 0.332733544917549 1.0 0.7571909364784671 56 Q14203,Q9Y496,Q9Y678,P27695,P78559,Q8TD16,A0AVF1,Q92572,P42858,P36405,O95817,P04792,O00203,Q9NZ32,O14617,P46821,Q9UBF2,Q13409,P43034,P07196 20 +Microtubule depolymerization 0.3850040163041409 0.9678768477074728 0.3331058783611618 1.0 0.757453255752806 18 O75122,P78559,P16949 3 +Signal transduction in absence of ligand 0.3905001808052514 0.9663496197131076 0.3338692646965069 1.0 0.7589193768549564 16 P30154,P30153,P49841,O95817,Q13546 5 +Axonal transport of mitochondrion 0.5747190759445013 0.9658671383036124 0.3341106678416179 1.0 0.7590775934360365 5 P07196,Q9NZ32 2 +Positive regulation of transmembrane transport 0.3155656398187878 0.9631823903497772 0.3354560007090814 1.0 0.7612137544489723 33 Q16539,P31751,Q9H4A3,P27695,Q00535,P28161,Q12955,Q06124,Q9UHD1,P0DP25,P42858 11 +Tissue migration 0.2855357331377233 0.9605410392229145 0.3367829867329059 1.0 0.763206976566733 60 P09429,Q16539,Q15555,P04083,P42785,P04792,P07737,O75122,Q16512 9 +Negative regulation of viral transcription 0.7232612507305954 0.960512195362723 0.3367974961821338 1.0 0.763206976566733 3 P19474,Q4G0J3 2 +Negative regulation of canonical wnt signaling pathway 0.3771048884653744 0.958680627760132 0.3377196605606007 1.0 0.763910592965353 20 Q16539,P49841,Q99471,Q9HCK8,Q13283,Q13043 6 +Regulation of neurotransmitter transport 0.3863104418470476 0.9571622754078544 0.3384853548062074 1.0 0.7644030786829497 17 P49841,Q4J6C6,P35080,Q15042,P0DP25 5 +Negative regulation of proteasomal protein catabolic process 0.365323049274243 0.954759209279299 0.3396994797806854 1.0 0.7655631127895586 23 P08238,Q99497,Q9UL15,O15372,O94966,P78559,Q96KB5,P60520,P54578,Q04323,Q9GZU8 11 +Positive regulation of hemopoiesis 0.3884386067051229 0.953230591718906 0.3404732496896456 1.0 0.7655631127895586 16 P09429,P00491,P04083,O00203,O14617,Q13546 6 +Regulation of cell projection size 0.6017869421058938 0.9526967977927884 0.3407437162861888 1.0 0.7655631127895586 4 P07196,Q6IBS0 2 +Establishment of planar polarity of embryonic epithelium 0.7211051857315418 0.9523485078589108 0.3409202645381175 1.0 0.7655631127895586 3 O95487 1 +Regulation of peptidyl tyrosine phosphorylation 0.3151561874090636 0.9517882701697948 0.341204372034797 1.0 0.7655631127895586 32 P30153,Q9H2J4,Q13177,Q06124,Q9UNH7,P14174 6 +Positive regulation of smooth muscle cell apoptotic process 0.5301120368983196 0.9509693923493568 0.3416199136207223 1.0 0.7662328923401842 6 P42771,Q53EL6 2 +Gdp mannose metabolic process 0.571064408244987 0.9501104985832236 0.3420561092323275 1.0 0.7666895178713033 5 Q13630,P34949,Q9Y5P6 3 +Positive regulation of neuron death 0.3791031315118131 0.9497545160206508 0.3422370020178791 1.0 0.7668342342970289 19 Q6SZW1,O95831,P49427,Q9UER7,P49841,P61081,P21359,Q13155,P17655,Q07820,Q00535 11 +Cellular response to mechanical stimulus 0.4666169764342848 0.947880144856773 0.3431904739351719 1.0 0.7687093456271332 8 O95817,Q99439 2 +Regulation of postsynapse organization 0.3846764307868586 0.9466357502705453 0.3438244202320586 1.0 0.7691279408345496 17 Q9NUL3,Q96HC4,P43034,P23528,Q12756,Q9UQB8,Q00535 7 +Chaperone mediated protein complex assembly 0.4263375395349801 0.9453004206062582 0.3445055237546166 1.0 0.7691279408345496 12 P08238,O15212,P78371,Q969U7,O95456,P07900 6 +Substrate dependent cell migration cell extension 0.5699297292890875 0.9452248104888556 0.3445441154861082 1.0 0.7691279408345496 5 Q14247,O00560,Q9Y5K6 3 +Response to ionizing radiation 0.2940029332776645 0.9435647570141308 0.3453921089903526 1.0 0.7702384243790273 48 Q16539,P04083,Q9H1E3,O60921,Q9Y620 5 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.4508869269334482 0.9423198839181396 0.3460288910128359 1.0 0.770876123540593 9 Q9NZZ3 1 +Connective tissue development 0.3381065737320065 0.9417653868105704 0.3463127700077109 1.0 0.7709010196577013 28 Q16539,Q96AQ6,P43490,Q8N0X7 4 +Intermediate filament bundle assembly 0.7181873617875718 0.9413179371992664 0.3465419533321516 1.0 0.7709010196577013 3 P07196 1 +Protein localization to vacuole 0.3538720575759912 0.9410838584355168 0.3466618867500575 1.0 0.7709010196577013 25 Q9UN37,Q96RL7,Q92783,O00203,P46934,P20645 6 +Developmental maturation 0.2918701927193881 0.9409792215711804 0.3467155074072234 1.0 0.7709010196577013 51 P46821,Q15645,Q5TAX3,Q8N2A8,Q9BQA1,Q15125,P07737,P07196,Q9BXS5,O14617 10 +Extracellular matrix disassembly 0.4339974840617753 0.940811735447466 0.3468013458537478 1.0 0.7709010196577013 11 O75122,Q96AQ6,A1X283,Q9BPX3 4 +Dna dependent dna replication maintenance of fidelity 0.3864051994092816 0.940309309904136 0.3470589255196015 1.0 0.7709010196577013 16 Q13535,Q9H1E3,Q9Y3Z3,Q9UNS1 4 +Regulation of neurogenesis 0.2800528462421818 0.939037811330367 0.3477113314118663 1.0 0.7709010196577013 63 P42345,Q9UPY3,Q02750,P55209,P27695,Q86VS8,Q96G23,P13010,Q9UQB8,P53990,O43379,Q16706,Q00535,P46821,Q9Y5A9,Q04917,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q8N0X7 22 +Activation of gtpase activity 0.3629893943497395 0.9383307301463664 0.3480744719994746 1.0 0.7711026928605322 23 P46109,P31751,Q8TC07,Q9NVG8,Q9H6U6,Q66K14,Q9P258,O60343,P46108 9 +Xenobiotic catabolic process 0.52727047480036 0.9379783968703356 0.3482555122144521 1.0 0.7711026928605322 6 P28161 1 +Taxis 0.2786950370720243 0.9379569105320668 0.3482665545248207 1.0 0.7711026928605322 76 P46108,P30046,P09429,Q16539,Q02750,Q96JJ3,Q9BVA1,Q9H4A3,P04083,P14174,Q16555,Q13740,P46109,P39019,P83731,P04792,Q9NUQ9,Q8N8S7,Q00535,Q9UIW2,P51452,O95747 22 +Mitochondrial fusion 0.3803373232622937 0.937399554640288 0.3485530699548489 1.0 0.7712862830286553 18 Q8N2A8 1 +Positive regulation of protein polyubiquitination 0.597962872412944 0.9368304762982096 0.3488457659403048 1.0 0.7716749292209696 4 Q13309,P98170 2 +Positive regulation of endothelial cell migration 0.3580151298706068 0.9359397627342592 0.349304202994547 1.0 0.7718677525926778 24 P09429,Q16539,P04083,P04792 4 +Regulation of toll like receptor signaling pathway 0.4246030526057788 0.9355470236223936 0.3495064614478875 1.0 0.7718677525926778 12 Q6SZW1,Q01804 2 +Positive regulation of leukocyte cell cell adhesion 0.3530346331239122 0.9349557084614668 0.349811125660898 1.0 0.7720046738614132 25 P09429,P00491,O95999,P04083,O00203,Q06124,Q9NUQ9,P23396,O14617 9 +Interleukin 1 production 0.4244843247095015 0.9348798231786936 0.349850236349509 1.0 0.7720046738614132 12 P04792,P04083 2 +Protein destabilization 0.4147424457643597 0.9329100538910772 0.3508664109360939 1.0 0.7724329710912261 13 P19474,P42858 2 +Negative regulation of calcium ion transport 0.4241133391889562 0.9327954052702444 0.3509256140132546 1.0 0.7724329710912261 12 P0DP25,P28161 2 +Proteolysis 0.3101812480976703 0.9314550543261184 0.3516182237379905 1.0 0.7724329710912261 423 Q15018,Q9H2J4,O75351,P49721,P30086,P28070,P61201,Q13200,Q13043,Q96E52,P81605,Q15370,P19474,Q96K76,P20618,Q9H3G5,Q0VDG4,P30740,Q96PU5,Q4G0X4,Q96RU2,Q9C0C9,Q4J6C6,O75832,Q9UKS6,Q9UBW8,P46934,Q9HD42,Q00535,Q01804,Q6P179,Q15392,P54727,P28072,P52888,P48147,P10398,Q13309,P49720,Q04323,Q9UBU6,Q8IYU2,Q93034,Q96FZ2,Q99497,O95155,P98170,Q92995,Q8WW12,Q9H1I8,P28074,P24941,P48729,Q9NZZ3,Q8N3C0,P60900,Q9NWV8,Q14674,Q96KB5,Q92688,P78318,P25788,P08238,P20810,P53990,Q99436,Q96FW1,Q86TI2,P42785,Q13177,Q13107,O14737,P68036,Q9GZP4,P61289,Q7Z6Z7,Q8NBM8,P28066,P49427,P62081,Q9UNS2,O95260,Q92905,Q9UN37,P51665,O43847,Q96J02,P48556,P09429,P62333,Q9NXV2,Q12765,P78559,P23396,P04080,P06744,P25789,Q8NEB9,Q7L5N1,Q92783,Q96KP4,Q15386,O95831,P54725,O94966,P25786,O43242,Q9BYT8,Q9UNM6,Q5T4S7,Q9UHG3,Q86Y37,P25787,P49841,P40818,Q9NZJ0,Q9UL46,O94888,O95999,Q9UNN5 120 +Camera type eye photoreceptor cell differentiation 0.711364300321373 0.9311248547453284 0.3517889831159257 1.0 0.7724329710912261 2 Q15555 1 +Retinal rod cell differentiation 0.711364300321373 0.9311248547453284 0.3517889831159257 1.0 0.7724329710912261 2 Q15555 1 +Retinal rod cell development 0.711364300321373 0.9311248547453284 0.3517889831159257 1.0 0.7724329710912261 2 Q15555 1 +Negative regulation of cell differentiation 0.2795428553094882 0.9305177022430522 0.352103102939826 1.0 0.7724329710912261 84 Q06124,Q9UPY3,Q9GZS3,P67809,P09429,Q00534,P04083,Q86VS8,Q96AC1,Q53EL6,Q96G23,Q92688,P49841,Q8WX92,Q15051,O15347,Q9P265,O95747,Q8N0X7 19 +Positive regulation of t cell proliferation 0.440445859810347 0.9304909340037784 0.3521169559920749 1.0 0.7724329710912261 10 P09429,P04083 2 +Negative regulation of cell cell adhesion 0.3693992184972479 0.9303104838729834 0.3522103512305015 1.0 0.7724329710912261 21 P09429,P04083,Q96J02,P51452 4 +Regulation of cell projection assembly 0.2885492615848603 0.9301814115515342 0.3522771645707083 1.0 0.7724329710912261 54 Q16658,O15144,P51114,P42345,Q9NVG8,Q4KMP7,P27816,P35080,Q12792,Q06787,P50570,P50395,P27695,Q9H6U6,Q9UHD8,P07737,Q9P258,P42858,P49841,P35241,Q14195,Q9NT62,P11233,Q15555,Q9NUL3,Q8TC07,P62330,Q6IBS0,Q66K14 29 +Bone development 0.3308714522275146 0.9295736227670076 0.3525918898013707 1.0 0.7724329710912261 29 Q16539,Q15125 2 +Regulation of dendrite morphogenesis 0.3820075419414481 0.9294702196575928 0.35264545171129 1.0 0.7724329710912261 17 Q9UQB8,P46934,Q96PU5 3 +Regulation of exosomal secretion 0.4484081984459003 0.9291387137034676 0.3528172036160697 1.0 0.7724329710912261 9 Q9UN37,O14964,O75351,Q92783,O00560 5 +Double strand break repair via break induced replication 0.4482448303887006 0.9282706597825436 0.3532671895296231 1.0 0.7731187652348723 9 Q9Y248,P25205,P33991,Q9BRT9 4 +Positive regulation of sodium ion transmembrane transport 0.4933617116836319 0.9267821625449852 0.3540396480695653 1.0 0.7731187652348723 7 Q9UHD1,Q9H4A3,P35754,Q12955 4 +Response to mercury ion 0.710195734735618 0.9264319186179852 0.3542215628228546 1.0 0.7731187652348723 2 Q99497 1 +Negative regulation of catabolic process 0.2706802025752267 0.9262674506496608 0.3543070069439546 1.0 0.7731187652348723 109 Q16539,Q13614,P16989,Q16850,Q9H2J4,Q96Q15,Q96HR8,Q14011,Q13526,Q96KB5,P67809,Q9H814 12 +Microtubule based transport 0.2854706405520706 0.9259173552770498 0.3544889312478236 1.0 0.7732597732579926 57 Q14203,Q9Y496,Q9Y678,P27695,P78559,Q8TD16,A0AVF1,Q92572,P42858,P36405,O95817,P04792,O00203,Q9NZ32,O14617,P46821,Q9UBF2,Q13409,P43034,P07196 20 +Corticosteroid receptor signaling pathway 0.4928094176855098 0.9241120444085898 0.3554279830194322 1.0 0.7747628282469317 7 P04150 1 +Positive regulation of phosphorus metabolic process 0.245543885587293 0.9236892963485388 0.3556481065344683 1.0 0.7747628282469317 150 Q96A49,Q8IV63,Q99497,Q99570,P51114,P36507,P33981,Q06124,Q13043,P35080,Q13526,Q93062,P51617,Q16512,O95429,Q02750,Q9H4A3,Q9NYB0,Q96AC1,Q14738,Q14012,P14174,Q9Y4R8,Q15435,P23396,Q05639,Q86Y37,Q9UNI6,P08238,P46109,P31751,Q96M27,Q13177,Q04637,O75832,Q9UHD1,Q13546,Q00535,O95999,P10398,P0DP25,Q9NQ88 42 +Regulation of gtp binding 0.4611977106758409 0.9200075787850888 0.357568798777103 1.0 0.7762530769803212 8 Q96AQ6,Q86YR5,P16949 3 +Positive regulation of chromosome condensation 0.5640350877192927 0.9198952192570872 0.357627517413414 1.0 0.7762530769803212 5 Q15021,O95347,Q9BPX3,Q15003 4 +Meiotic chromosome condensation 0.564035087719292 0.9198952192570844 0.3576275174134156 1.0 0.7762530769803212 5 Q15021,O95347,P42695,Q15003 4 +N terminal peptidyl methionine acetylation 0.7124090118075622 0.9195353181976562 0.357815641111973 1.0 0.7764057624128132 3 Q5VZE5 1 +Regulation of nervous system process 0.4216321719854267 0.9188692262384844 0.3581639779627856 1.0 0.776431796139478 12 Q9UQB8,Q13614 2 +Regulation of stress granule assembly 0.5933890620157023 0.9179015193748672 0.3586704261432125 1.0 0.7769947894194853 4 Q13283,Q9UN86 2 +Positive regulation of protein containing complex disassembly 0.4912699599149818 0.9166741698341866 0.359313405372466 1.0 0.7776080000706816 7 P63241,Q13137,P60981,P48681 4 +Cell chemotaxis 0.2990216535196362 0.915519384916912 0.3599190306085531 1.0 0.7778971310726499 42 P09429,Q96JJ3,P46109,Q9H4A3,P39019,P04083,O95747,P14174,P04792,P46108,P30046 11 +Endosome organization 0.3088886356105036 0.9132192893025408 0.3611272209595568 1.0 0.7794861298511456 34 Q15075,Q9UN37,P53990,Q9H267,Q9NZZ3,O75351,Q8NEB9,Q86VS8,O60493,P40818,Q92783,Q9HD42 12 +Purine nucleotide salvage 0.5619883040935713 0.9111213639658944 0.3622314310020389 1.0 0.77984032457131 5 Q01433,P55263,P07741,P00492 4 +Purine ribonucleotide salvage 0.5619883040935713 0.9111213639658944 0.3622314310020389 1.0 0.77984032457131 5 Q01433,P55263,P07741,P00492 4 +Regulation of cilium assembly 0.3732033443129021 0.9107849722587904 0.3624086820513261 1.0 0.77984032457131 19 Q15555,P50570,P49841,Q8TC07,Q9NVG8,P27695,Q9UHD8,Q4KMP7,P27816,Q66K14,Q9NT62,P42858 12 +Regulation of cardiac muscle contraction by calcium ion signaling 0.5212227102594262 0.9104003097174396 0.3626114344657578 1.0 0.77984032457131 6 P28161 1 +Establishment of epithelial cell apical basal polarity 0.5212050307107274 0.9103198399968222 0.3626538583659255 1.0 0.77984032457131 6 P26038,P15311,O14745,P60953,Q13308 5 +Nuclear transcribed mrna catabolic process exonucleolytic 0.4013138363270236 0.9102116001670962 0.362710927660139 1.0 0.77984032457131 14 Q96C86,Q969T7,Q9Y2L1 3 +Regulation of phospholipid metabolic process 0.4283071230884765 0.909475346240665 0.3630992656772798 1.0 0.7801663491996833 11 O75874 1 +Dna catabolic process 0.489691737652076 0.9090564979558514 0.363320303792376 1.0 0.780386915151301 7 Q9UPY3,O95831 2 +Cellular response to abiotic stimulus 0.2755382048650469 0.908521204912438 0.3636029156415952 1.0 0.7804270423945158 74 Q16539,P16989,O95817,Q13535,Q9H1E3,Q99439,Q96KB5,P46934,O60921 9 +Regulation of cell matrix adhesion 0.3384144803913312 0.902215781574988 0.3669422530435922 1.0 0.7833171412122278 27 Q13630,Q00534,P49841,P42771,Q96AC1,Q9H6U6,P51452,O75122,Q7Z460 9 +Protein deglycosylation 0.559811677932641 0.9018036554808568 0.3671611776124657 1.0 0.7835025084205346 5 O60502,Q99497 2 +Regulation of cell division 0.3054382126169168 0.9010887709314584 0.3675411228254606 1.0 0.7835805568128836 36 Q9UN37,P41208,P0DP25,Q13526,P67809 5 +Positive regulation of chemotaxis 0.3746407790870925 0.9003524706287042 0.367932705975136 1.0 0.7838394441002444 18 P09429,O95747,P04792 3 +Mitotic cytokinetic process 0.4182966961147066 0.9001897540001123 0.3680192778352937 1.0 0.7838394441002444 12 Q9NZZ3,Q9UN37,Q9HD42 3 +Dna replication synthesis of rna primer 0.7069823873020897 0.8991579777932427 0.3685685198513795 1.0 0.7847361419556902 3 P49642 1 +Sodium ion transport 0.3325013139447274 0.8980927262855374 0.3691361165247069 1.0 0.784768584338207 28 Q9H4A3,Q9UHD1,Q12955,O43865,Q9Y6M7,O95747,P46934,Q96PU5 8 +Regulation of translational termination 0.5878398129202098 0.8950113020573162 0.3707810463345904 1.0 0.7860105869623165 4 P63241,P62495,P15170 3 +Positive chemotaxis 0.4867301606148326 0.8947830649730188 0.3709030648860714 1.0 0.7860105869623165 7 P09429,P17931,O14786,P26583,P14174 5 +Cellular response to ionizing radiation 0.3475207499057707 0.8947397529118075 0.3709262228979009 1.0 0.7860105869623165 25 Q16539,O60921,Q9H1E3 3 +Regulation of reactive oxygen species metabolic process 0.3065709626599819 0.8929889384543523 0.3718630963815645 1.0 0.7866880752578669 34 P00374 1 +Mrna pseudouridine synthesis 0.5872430224408667 0.8925548014140344 0.3720956330869629 1.0 0.7866880752578669 4 Q96PZ0,Q8WWH5 2 +Transforming growth factor beta production 0.7017236342389765 0.8925437566624002 0.3721015501598952 1.0 0.7866880752578669 2 P08238 1 +Negative regulation of transforming growth factor beta production 0.7017236342389765 0.8925437566624002 0.3721015501598952 1.0 0.7866880752578669 2 P08238 1 +Regulation of extrinsic apoptotic signaling pathway 0.3043011551914915 0.8909952772452068 0.3729317038881845 1.0 0.7875468335825664 36 Q99497,Q99504,P30153,P30154,P49841,O95999,Q9UNN5,Q13177,Q13043,P61289,Q13546,P42858 12 +Protein targeting to lysosome 0.4165361234408675 0.8903505661780271 0.373277677247402 1.0 0.7875468335825664 12 O00203,P46934,P20645 3 +Peptidyl methionine modification 0.5864565527389044 0.8893191457952094 0.3738315847701501 1.0 0.7880709327805658 4 Q5VZE5 1 +Immunological synapse formation 0.7040441525954924 0.888158651087717 0.3744554172595926 1.0 0.788629428298797 3 P17931 1 +Gtp biosynthetic process 0.5564816722093686 0.8875750333851841 0.3747693883864826 1.0 0.7887307636554391 5 P15531 1 +Cytoskeleton dependent intracellular transport 0.2729325424747066 0.8871321799472277 0.3750077405621068 1.0 0.7887307636554391 65 Q14203,Q9Y496,Q9Y678,Q86VS8,P27695,P07437,P78559,Q8TD16,A0AVF1,Q92572,P42858,P36405,O95817,P04792,O00203,Q9NZ32,O14617,P46821,Q9UBF2,Q13409,P43034,P07196 22 +Negative regulation of receptor signaling pathway via jak stat 0.6996786444639308 0.8844012240235047 0.376479662456989 1.0 0.7898643968543831 2 P30153 1 +Negative regulation of receptor signaling pathway via stat 0.6996786444639308 0.8844012240235047 0.376479662456989 1.0 0.7898643968543831 2 P30153 1 +Negative regulation of leukocyte proliferation 0.439909667280385 0.8841056709883988 0.3766391721774049 1.0 0.7898738320576189 9 Q96J02 1 +Cell junction maintenance 0.454158815903607 0.8839488860003096 0.3767238058235973 1.0 0.7898738320576189 8 Q96AC1,Q14203 2 +Myelin maintenance 0.5554175858314256 0.8830353425924924 0.3772171763045766 1.0 0.7906394327352121 5 Q9Y2J2 1 +Cd4 positive alpha beta t cell activation 0.5151529511057548 0.8828287003895563 0.3773288312173812 1.0 0.7906394327352121 6 P04083 1 +Protein modification by small protein conjugation 0.268876226222535 0.8809601034662766 0.3783394144151897 1.0 0.7911483786584577 198 Q9GZZ9,Q93034,Q9NVI1,O75155,Q99497,P62942,O95155,P98170,Q9UBE0,P61081,Q8WW12,P07900,P15880,Q5W0B1,Q5T4S7,Q96J02,Q13526,Q86UK7,O60678,Q15370,Q9BSL1,Q8TBC4,Q8N806,P19474,Q9HC52,P62841,Q14527,Q16763,P63208,P31689,Q9H1B7,P23396,Q96PU5,O75448,P08238,Q4G0X4,Q96FW1,Q6DKJ4,Q93008,Q13107,Q9C0C9,P68036,O75832,Q15386,Q9UHD1,Q7Z6Z7,Q9NZJ0,P46934,Q9NT62,Q8TDB6,Q00535,Q96GG9,P49427,P62081,O95999,Q9UER7,Q9NXF7,Q9UBV2,Q9UII4,P52888,Q9Y4B6,Q96DY7,Q86VP6,Q13309,Q9Y314,Q9UBT2,Q04323,Q8IYU2 68 +Cytoplasmic microtubule organization 0.3716221118250495 0.8807990675774309 0.3784265845234744 1.0 0.7911483786584577 18 Q9BSJ2,Q86VS8,P23258,P43034,P15311,Q9H2G2,Q14203,Q9UHD1,Q7Z460 9 +Positive regulation of non motile cilium assembly 0.5839072263623535 0.8788435801886316 0.3794860932090307 1.0 0.7911483786584577 4 P27695,Q15555 2 +Cochlea development 0.5543859649122738 0.8786374856528686 0.379597864100003 1.0 0.7911483786584577 5 P43034,Q9BW83,P33993,P49736 4 +Dna catabolic process endonucleolytic 0.5141782999016324 0.8784121783642806 0.3797200777697433 1.0 0.7911483786584577 6 Q9UPY3,O95831 2 +Positive regulation of dna demethylation 0.7014301699138075 0.8783940835709246 0.379729893996954 1.0 0.7911483786584577 3 Q01804 1 +Cell morphogenesis involved in differentiation 0.2379082715602966 0.8772248074082772 0.3803645442692764 1.0 0.7914060260360595 135 Q12955,Q06124,O43251,P46108,P16949,Q16512,O60678,Q6SZW1,Q02750,Q9BVA1,Q96AC1,Q9P258,O95487,Q9Y4F1,Q9UQB8,P78559,Q16555,Q13740,Q96PU5,P08238,P53990,P46109,P49841,P83731,Q13177,Q8N8S7,P46934,Q00535,P46821,Q9Y5A9,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q8N0X7 37 +Actin cytoskeleton reorganization 0.3450458733887709 0.8767709121139622 0.3806110813878367 1.0 0.7914060260360595 25 P04083,P15311,Q9UQB8,Q16512,Q00535 5 +Type b pancreatic cell development 0.5832564556569402 0.8761726484326557 0.3809361833453302 1.0 0.7914060260360595 4 Q00534 1 +Positive regulation of extracellular matrix disassembly 0.7007597895967297 0.8758931185486729 0.3810881408711555 1.0 0.79147228248981 3 O75122,Q7Z460 2 +Pseudouridine synthesis 0.4521218448641372 0.8735476711465582 0.3823646343926219 1.0 0.7927022008876412 8 Q96PZ0,Q96HR8,Q8WWH5 3 +Intermediate filament organization 0.482131900001932 0.8726801688019945 0.382837429867791 1.0 0.7931063286261717 7 P07197,O75190,P07196 3 +Regulation of cyclin dependent protein kinase activity 0.3535298498632807 0.8721311639586458 0.3831368267578203 1.0 0.7934772108035035 23 P08238,O95373,Q16543,Q9UII4,Q96SZ6,Q9P287,P42771,O95067,O75832 9 +Sequestering of calcium ion 0.3671420040427954 0.8709702293714506 0.383770408461781 1.0 0.7941189012895894 19 P0DP25,P62942,P28161 3 +Negative regulation of actin filament polymerization 0.3570474538876959 0.8706191885174066 0.3839621157260988 1.0 0.7941883485617959 22 P58546,P47755,Q9BPX3,Q9UEY8,P07737,P35241,P35080,Q9NUQ9,Q6IBS0,Q13045,Q12792 11 +Negative regulation of viral process 0.3695720171155244 0.8675534406336343 0.3856388442501224 1.0 0.7966566158874355 18 P19474,Q13325,Q96SB4,O60493,P42224,Q9NZI7,Q15047,Q13263,P19525,Q4G0J3 10 +Regulation of filopodium assembly 0.3938295209905773 0.8659024372873049 0.3865436664224986 1.0 0.7969810253616595 14 Q16658,O14786,P51114,Q9NUL3,Q9H6U6,P62330,Q14195,P47756,P11233,Q06787 10 +Microtubule bundle formation 0.3746013024994475 0.8657228058771524 0.3866421903984507 1.0 0.7969810253616595 16 P46821,Q15691,Q15555,O43670,Q86Y56,Q9UHD1,A0AVF1 7 +Germ cell development 0.2961053230134164 0.861255333454252 0.3890974304675807 1.0 0.7993046131472163 40 Q9Y5A9,P30153,P42345,Q15645,Q5TAX3,Q8N2A8,Q96SB4,Q9BQA1,P43034,Q9GZP4,P62826,O14965,A0AVF1,O60879,Q92879 15 +Multicellular organismal movement 0.435138212124215 0.8589443492668978 0.3903712198325004 1.0 0.8000929225940376 9 P28161 1 +Positive regulation of signal transduction by p53 class mediator 0.4270348359473472 0.8582823726572162 0.3907365605582136 1.0 0.8000929225940376 10 Q13535,P62081,P62841 3 +Regulation of leukocyte differentiation 0.3270938670366218 0.8562485492329472 0.3918603136388601 1.0 0.8009746317852297 28 P09429,P17931,Q00534,O15347,P00491,Q9BXW9,P04083,O00203,O14617,Q13546 10 +Pentose phosphate shunt 0.4485208931002579 0.8552008692537845 0.3924399550762425 1.0 0.8016622819530805 8 Q9NQ88,P37837,P18669 3 +Neuron projection arborization 0.4784370372214769 0.8549752097658985 0.3925648718919494 1.0 0.8016690320668312 7 Q13464,Q9HCE1,Q15334,O14786 4 +Negative regulation of wnt signaling pathway 0.3419499775187281 0.8543717730671607 0.3928990307155091 1.0 0.8018479715881766 25 Q16539,P49841,Q99471,Q6DKJ4,Q9HCK8,Q13283,Q13043 7 +Positive regulation of establishment of protein localization to mitochondrion 0.4100361806489427 0.8541580658031839 0.3930174144722995 1.0 0.8018479715881766 12 Q9UBE0,O14737,P68036,P19784,Q7Z6Z7 5 +Positive regulation of lymphocyte differentiation 0.4340695058470416 0.853322085702397 0.3934807156761766 1.0 0.8022965907013164 9 O00203,P04083,O14617 3 +Body morphogenesis 0.4480265129123005 0.8526862103184142 0.3938333399858047 1.0 0.8025191274146599 8 O75122,Q06124,Q15042 3 +Homologous recombination 0.4096766799097894 0.8521628257287264 0.3941237260843344 1.0 0.8028626706884835 12 Q9H1E3,Q9Y620 2 +Positive regulation of protein serine threonine kinase activity 0.3007637324797695 0.8507539068200207 0.3949060711531822 1.0 0.803402535762251 35 Q96A49,Q02750,P0DP25,P36507,P23396,Q96AC1,Q9Y4R8,Q13043,O75832,Q14012,P14174,P51617,Q16512 13 +Regulation of cellular carbohydrate metabolic process 0.3209264031756174 0.8506337310986983 0.3949728458137933 1.0 0.803402535762251 29 Q9BYT8,Q9UNI6,P85037,O14874,P18669,P49841,A6NDG6,Q13043,Q9NQ88 9 +Glutamine metabolic process 0.3912172089585829 0.8505103356042046 0.3950414166183527 1.0 0.803402535762251 14 P17812,Q06210,Q06203,Q9NRF8,P49915 5 +Protein stabilization 0.2721906764237486 0.8502289343906325 0.3951978180287057 1.0 0.803402535762251 79 Q99497,Q9H2J4,Q92995,Q13043,P35080,Q13526,O95429,P83436,Q16543,Q9BXJ9,P07737,Q9Y4R8,Q5HYI8,O43670,O95817,Q9UHD1,P62081,Q9UNS2,O94966 19 +Regulation of myelination 0.4169575004370161 0.8473907159001121 0.3967773776021188 1.0 0.8048105496542106 11 Q13614,Q96P11,Q9UPY3 3 +Collateral sprouting 0.6929988555832564 0.8470403662183573 0.3969726222361638 1.0 0.8048105496542106 3 Q8N0X7 1 +Positive regulation of autophagy 0.3028531465880297 0.8463228730026126 0.3973726513187658 1.0 0.8048105496542106 32 P09429,P19474,P78356,Q86YR5,P49841,O95817,Q15042,Q13137,P42858 9 +Positive regulation of microtubule polymerization or depolymerization 0.3686351747527608 0.8440736381527045 0.39862825770629 1.0 0.8052413134916654 17 P46821,Q15691,Q14203,P23396,Q16512 5 +Neurofilament cytoskeleton organization 0.6894536955886801 0.8439242820458448 0.3987117183308246 1.0 0.8052413134916654 2 P07196 1 +Sarcoplasmic reticulum calcium ion transport 0.4461946927630886 0.8433778723335018 0.3990171433026364 1.0 0.805611334962015 8 P28161 1 +Regulation of leukocyte proliferation 0.3403261836682258 0.8426605459489526 0.399418318764861 1.0 0.8057092077009331 25 P09429,P04083,Q96J02,P14174,P23396,Q16512 6 +Response to calcium ion 0.3448752088774052 0.8424186239234029 0.3995536719619008 1.0 0.8057092077009331 24 O43865,P46934,Q86YQ8 3 +Positive regulation of protein sumoylation 0.5456108103790721 0.8413686313789275 0.4001414530247476 1.0 0.8057484264674388 5 Q9UBE0 1 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.5745822289334941 0.8407021946316764 0.4005147908066055 1.0 0.8057484264674388 4 Q16512,Q13309 2 +Dendrite self avoidance 0.6885772713993576 0.8404740113883838 0.4006426671170495 1.0 0.8057484264674388 2 P35613 1 +Protein localization to nuclear body 0.4156359743878423 0.8402028927590774 0.4007946367565935 1.0 0.8057484264674388 11 P17987,P50991,P78371,P40227,Q99832,P48643,Q4G0J3,P49368 8 +Establishment of golgi localization 0.5735165156387141 0.8363619186930473 0.4029513291877169 1.0 0.8072321616615296 4 P63104,Q9Y678,O14745 3 +Pathway restricted smad protein phosphorylation 0.4745384786947414 0.8363519532117355 0.4029569337975183 1.0 0.8072321616615296 7 Q13526,P33981 2 +Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.5734795711622875 0.8362115290599815 0.403035913632751 1.0 0.8072321616615296 4 P49327,Q99497 2 +Cytoskeleton dependent cytokinesis 0.2831772403550458 0.8357717008440818 0.4032833496140329 1.0 0.8072321616615296 48 Q9UN37,Q6DKK2,P53990,Q9NZZ3,P40818,Q12955,Q14674,P16949,Q15019,Q9HD42 10 +T cell differentiation 0.3293810370202082 0.8339848838121641 0.4042895020309573 1.0 0.8073542554947201 27 P09429,P24390,Q00534,P00491,Q9BXW9,P04083,O00203,O14617,Q6NYC1,Q5HYI8 10 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.5437077148459126 0.8333211072266232 0.4046636553317455 1.0 0.8075042509141154 5 P09429,P62333 2 +Response to uv 0.2886484315403316 0.8323310717257602 0.4052220967876052 1.0 0.8075042509141154 43 Q96K76,O95155,Q15004,Q14011,Q13535,Q9NZJ0,Q96KB5,P46934,O60921,P39748 10 +Response to fungus 0.4297465607470611 0.830633323219055 0.4061808038170778 1.0 0.8083329506083796 9 P81605 1 +Regulation of vasculature development 0.2940264582855508 0.8305089817004545 0.4062510718090961 1.0 0.8083329506083796 39 Q9H2J4 1 +Negative regulation of phagocytosis 0.4433360578179154 0.8288817197046754 0.407171340377594 1.0 0.8087251310754202 8 P09429,Q9NT62,Q99439 3 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.405233046296611 0.827561344598101 0.4079189674730976 1.0 0.8087251310754202 12 P62942,Q13526 2 +Regulation of protein targeting 0.3334606410055764 0.8274233105615486 0.4079971727533307 1.0 0.8087251310754202 26 P31751,Q9UBE0,O95817,O14737,Q12955,P68036,Q9UHD1,Q7Z6Z7,O95429,Q00535 10 +Interleukin 1 mediated signaling pathway 0.542291809177262 0.8273423434547896 0.4080430500541334 1.0 0.8087251310754202 5 Q01804 1 +Melanocyte differentiation 0.6873479143663941 0.8261547923936465 0.4087162891702098 1.0 0.8093382379602262 3 Q92995 1 +Positive regulation of glucose transmembrane transport 0.5021695543916084 0.8242694886847155 0.4097864511161631 1.0 0.8102316393994443 6 Q16539,Q06124 2 +Somatic diversification of immune receptors 0.3328790062641487 0.8231595176650747 0.4104172865491475 1.0 0.8107494015379025 26 Q9UQ84,O96028,P13051 3 +Replication fork processing 0.4043874964267534 0.8228933225577051 0.4105686602967808 1.0 0.8107953889511322 12 Q9H1E3 1 +Dna recombination 0.2650914810697684 0.8222706246055221 0.4109228914459371 1.0 0.8107953889511322 106 P09429,P52294,Q9H4L7,O15347,Q9BRT9,Q15645,Q9UQ84,P35244,Q9NYB0,P38935,Q9H1E3,O96028,P13051,Q15631,O60921,Q9Y620 16 +Methylglyoxal metabolic process 0.6862480742592882 0.8221025250569084 0.4110185485170632 1.0 0.8107953889511322 3 Q04760 1 +Demethylation 0.3531924455682869 0.8209735443281476 0.4116613376665037 1.0 0.8113340564304625 21 Q9UPP1,Q01804,Q16850 3 +Spermatid differentiation 0.3563416873236785 0.8204022378365722 0.4119868401736646 1.0 0.8113340564304625 20 Q15645,Q8N2A8,Q9GZP4,A0AVF1 4 +Negative regulation of actin filament depolymerization 0.3622085105770619 0.820227590437627 0.4120863761794551 1.0 0.8113340564304625 18 P58546,P47755,Q9BPX3,Q9UEY8,P35241,Q6IBS0,Q9UHB6,Q13045,Q12792 9 +Nik nf kappab signaling 0.3592332783986156 0.8194199453937091 0.4125468591124654 1.0 0.8113340564304625 19 Q9NYB0,P15311,Q53EL6,Q9UPY3,P23396 5 +Regulation of mrna catabolic process 0.2703086322580823 0.8190156624362288 0.412777477596894 1.0 0.8113340564304625 83 Q16539,P16989,Q96C86,Q5TAX3,Q9HCE1,Q969T7,Q14011,P67809 8 +Oligodendrocyte differentiation 0.3528673022485237 0.8188020252058265 0.412899375299653 1.0 0.8113340564304625 21 P18074,P41240,P49770,Q14232,P42345,Q9NR50,P21359,Q9UI10,Q00535,Q13144,Q96P11,Q92542 12 +Multivesicular body sorting pathway 0.394835646882177 0.8187852369143037 0.4129089553117286 1.0 0.8113340564304625 13 Q92783,Q9NZZ3,Q9HD42 3 +Endosome transport via multivesicular body sorting pathway 0.394835646882177 0.8187852369143037 0.4129089553117286 1.0 0.8113340564304625 13 Q92783,Q9NZZ3,Q9HD42 3 +Positive regulation of interleukin 1 production 0.4413337575527803 0.8187506979042412 0.4129286649460257 1.0 0.8113340564304625 8 P04792 1 +Retrograde transport vesicle recycling within golgi 0.5006999291543357 0.8176811669224149 0.4135392670171178 1.0 0.8122916710896426 6 Q9UP83 1 +Trna 5 end processing 0.5002506354887178 0.8156687487116254 0.4146896175264705 1.0 0.8138237447854998 6 Q99575,P05455 2 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2773677178780525 0.8142988016744908 0.4154737960501717 1.0 0.8147360781660209 54 P48729,P08238,Q99497,P49841,P54727,P10398,O75832,P24941,P54725,P78559,Q96KB5,Q15370,Q04323 13 +Cellular detoxification of aldehyde 0.5388888888888882 0.8130042736816466 0.4162156078966053 1.0 0.8147360781660209 5 Q8TC12,P11766,P10768,Q99497 4 +Platelet morphogenesis 0.4695989732980766 0.8128478763824917 0.4163052821595685 1.0 0.8147360781660209 7 P78527,Q06124,P12814 3 +Protein maturation by protein folding 0.4695676888609514 0.8126993567123476 0.4163904501427979 1.0 0.8147360781660209 7 P62942 1 +Regulation of supramolecular fiber organization 0.263707373743434 0.8118626871079802 0.4168704268916334 1.0 0.8154331911185898 107 Q9NQP4,O15144,Q15691,Q99497,P47755,P42345,Q14203,P35080,P16949,Q16512,O95429,Q9UHV9,Q99471,Q96AC1,P07737,Q9UQB8,P78559,P23396,O60504,O15212,P36405,O75116,Q13177,Q9BPX3,P60983,P35241,Q14019,Q9NUQ9,Q02790,P46821,P60981,P61758,P62330,Q6IBS0,O75122,Q7Z460,P04350 37 +Negative regulation of phosphoprotein phosphatase activity 0.4258790686523616 0.8104122297147425 0.4177032913038223 1.0 0.816819963297181 9 P49841,Q15257,P17931,P62942 4 +Cellular response to external stimulus 0.2769560279257346 0.8100796330553871 0.4178944090927237 1.0 0.816951347787436 54 Q9H773,Q96C86,Q99439 3 +Blood vessel endothelial cell migration 0.3210109091681627 0.8095698169864243 0.4181874612524088 1.0 0.8170377848611237 28 P04792,Q16539,P04083,P42785 4 +Embryonic body morphogenesis 0.6827565946045715 0.8092668553680985 0.4183616667721002 1.0 0.8170377848611237 3 O75122 1 +Protein localization to lysosome 0.3655127782553302 0.808889674194712 0.4185786088648111 1.0 0.8170773436887281 16 O00203,P46934,Q9UN37,P20645 4 +Endocrine pancreas development 0.4392662696444322 0.8083102886952487 0.4189119811155528 1.0 0.8171152539365173 8 P04083,Q00534 2 +Regulation of calcium ion transmembrane transport 0.3442331699347577 0.8078098771721024 0.4192000382664651 1.0 0.8171152539365173 23 P0DP25,P62942,P28161 3 +Meiosis ii cell cycle process 0.6801051709027287 0.8072888169998588 0.4195001053910561 1.0 0.8171152539365173 2 P30153 1 +Meiotic sister chromatid cohesion centromeric 0.6801051709027287 0.8072888169998588 0.4195001053910561 1.0 0.8171152539365173 2 P30153 1 +Protein localization to cell junction 0.3475810078427524 0.8061828294883382 0.4201374376860523 1.0 0.8171152539365173 22 Q96AC1,Q9UQB8,P04792 3 +Methylguanosine cap decapping 0.4388250489759634 0.806084974624201 0.4201938545497723 1.0 0.8171152539365173 8 Q96C86,Q9NPI6,Q9BQG2 3 +Rna decapping 0.4388250489759634 0.806084974624201 0.4201938545497723 1.0 0.8171152539365173 8 Q96C86,Q9NPI6,Q9BQG2 3 +Eye photoreceptor cell development 0.5660441121774563 0.806046408929374 0.4202160902884291 1.0 0.8171152539365173 4 Q15555 1 +Positive regulation of transferase activity 0.2588969374896693 0.8048313473620694 0.4209170095888144 1.0 0.8171702451497173 113 Q9Y248,Q96A49,Q99497,Q99570,P42345,P36507,P40938,P15880,Q13043,Q13526,P49643,P51617,Q96HR8,Q16512,Q02750,Q9H4A3,Q16763,P78371,P63208,Q96AC1,P13010,Q14012,P14174,Q9Y4R8,P23396,Q05639,Q86Y37,Q9UNI6,P08238,Q96M27,Q13177,Q92616,P68036,O75832,Q8TDB6,Q00535,Q96GG9,O95999,Q9BRT9,Q9UER7,P0DP25,Q9NQ88,P07900 43 +Negative regulation of respiratory burst 0.67893660531698 0.8027362512669953 0.422127195272826 1.0 0.8171702451497173 2 P39019 1 +Negative regulation of tissue remodeling 0.6789366053169736 0.8027362512669707 0.4221271952728402 1.0 0.8171702451497173 2 P41240 1 +Regulation of adaptive immune response 0.3566357333334837 0.8026008366302924 0.4222054846327925 1.0 0.8171702451497173 19 P09429,P04083,Q16512,O96028 4 +Hemostasis 0.3346493836528705 0.8019361911852035 0.4225898697616776 1.0 0.8171702451497173 25 P06744,Q16539,Q9C0E8,P04792,O00203 5 +Regulation of hemopoiesis 0.2780456439709854 0.8008946211379347 0.4231926543014992 1.0 0.8173706349708417 51 P09429,Q16539,P17931,Q00534,O15347,P00491,Q9BXW9,P04083,O95251,O00203,Q9GZS3,Q9GZP4,O43251,O14617,Q13546 15 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.4239292097226007 0.8002469593347973 0.4235677272353624 1.0 0.8177341747413911 9 P42771,Q96SZ6 2 +Lysosomal microautophagy 0.6780601811276679 0.7993259004852739 0.4241014643374359 1.0 0.818406572866621 2 Q9Y4P1 1 +Glucose 6 phosphate metabolic process 0.4078271668075164 0.7979317002536048 0.4249101261974133 1.0 0.8197271149819575 11 P06744,Q9NQ88,P37837,P18669 4 +Regulation of glucose import 0.4370514553934104 0.7971498489273169 0.4253640083539065 1.0 0.8203626515707875 8 Q16539,Q06124 2 +Mononuclear cell migration 0.3291347873604482 0.7958060357476024 0.4261447830069447 1.0 0.8209082589090114 26 P09429,P46109,O95747,P04083,P46108 5 +Peptidyl histidine modification 0.5347278508280796 0.7955339808143631 0.4263029525114863 1.0 0.8209725571007063 5 Q9BTV6,P22392 2 +Positive regulation of activated t cell proliferation 0.6784739461203422 0.7935834406908173 0.4274379757635804 1.0 0.8217776694723936 3 P09429 1 +Interferon gamma mediated signaling pathway 0.5340604300198057 0.792738387407799 0.4279302599678778 1.0 0.8221314759571354 5 P42224,P08238,Q16543 3 +Plasma membrane repair 0.4360138727267806 0.7919302663267154 0.4284013379722027 1.0 0.8221314759571354 8 Q9HD42 1 +Glycerolipid biosynthetic process 0.2775629563860206 0.7904317354325776 0.4292756745723451 1.0 0.8233300107014546 50 Q13614,P42356,Q96Q15,Q8NEB9,Q9NPH0,Q9HBU6,Q8NCE2,P35790 8 +Regulation of meiotic cell cycle phase transition 0.6754309085597621 0.7891161318721225 0.4300441341846972 1.0 0.8237206554691743 2 P33981 1 +Amp salvage 0.5618240280619808 0.7890211817861195 0.430099626542701 1.0 0.8237206554691743 4 P55263,P07741,P00492 3 +Nucleotide excision repair dna gap filling 0.6751387671633176 0.7879837091672139 0.430706234939447 1.0 0.8237206554691743 2 Q07864 1 +Calcium ion transport into cytosol 0.3543637839182252 0.7879398484814811 0.4307318911364843 1.0 0.8237206554691743 19 P0DP25,P62942,P28161 3 +Podosome assembly 0.4643080102312751 0.7877947058040554 0.4308167982999169 1.0 0.8237206554691743 7 A1X283,P26038,Q9BPX3 3 +Changes to dna methylation involved in embryo development 0.6745544843704354 0.7857200754788006 0.432031499310237 1.0 0.8245372447750672 2 Q13263 1 +Dsrna processing 0.344495279249901 0.7853659754422186 0.4322390237646578 1.0 0.8246945425923659 22 Q02750,Q13546,Q5TAX3,Q9UPY3,Q15631,Q99598 6 +Regulation of g0 to g1 transition 0.6736780601811277 0.7823276719829958 0.4340220282679077 1.0 0.825960681185302 2 Q15648 1 +G0 to g1 transition 0.6736780601811277 0.7823276719829958 0.4340220282679077 1.0 0.825960681185302 2 Q15648 1 +Positive regulation of g0 to g1 transition 0.6736780601811277 0.7823276719829958 0.4340220282679077 1.0 0.825960681185302 2 Q15648 1 +Uv damage excision repair 0.5600701549254643 0.7819669674697979 0.434233986774212 1.0 0.825960681185302 4 Q16531,Q13620,Q96EB6 3 +Centromere complex assembly 0.4926314603552444 0.7816739722487698 0.4344062017095633 1.0 0.825960681185302 6 P49321 1 +Axon ensheathment in central nervous system 0.6733859187846942 0.7811976881026805 0.4346862332628221 1.0 0.8260166185265273 2 P18074 1 +Base excision repair 0.3468355343480981 0.7787040023795833 0.4361540978920226 1.0 0.8278513715243919 21 Q07864,Q96K76,P12004,P35244,P27695,Q86W56,P15927,Q7Z6Z7,P13051,P28340,P23396,P18858,P39748 13 +Regulation of response to cytokine stimulus 0.3005251317264919 0.7774962254578308 0.4368660605217893 1.0 0.8285165590451322 31 P08238,Q01804,P98170,Q16543,Q9Y3Z3,Q7Z739,P43034,Q06124,P51617,Q13546 10 +Regulation of cd4 positive alpha beta t cell activation 0.672590301991145 0.7721515362788914 0.4400246815205082 1.0 0.8312558227696906 3 P04083 1 +Negative regulation of cd4 positive alpha beta t cell activation 0.672590301991145 0.7721515362788914 0.4400246815205082 1.0 0.8312558227696906 3 P04083 1 +Negative regulation of microtubule polymerization or depolymerization 0.359433689653193 0.771230331387631 0.4405704187864192 1.0 0.8315190119258951 16 P46821,Q15691,O75122,P16949,Q7Z460,P04350 6 +Mrna catabolic process 0.2564016427548358 0.7700852795004525 0.4412493074411387 1.0 0.8319541239751788 113 Q16539,P16989,Q96Q15,Q96C86,Q5TAX3,Q9HCE1,Q9BQG2,Q969T7,Q14011,P67809,P05455 11 +Positive regulation of cell cycle g1 s phase transition 0.3486247924905494 0.7698967296618571 0.4413611540021309 1.0 0.8319541239751788 20 P31350,P04083,P27695,Q96DY7,Q04637,P35241,Q6UVJ0,P23921 8 +Regulation of actin filament based process 0.2659472864312324 0.7688491390963137 0.4419828737216202 1.0 0.8319541239751788 93 Q16658,O15144,P47755,P42345,P15311,P35080,P46108,P16949,Q16512,O95429,Q9Y281,Q9H6U6,Q96AC1,P07737,Q9H8V3,Q9UQB8,P30626,O60504,O75116,Q13177,Q9BPX3,P60983,P35241,Q14019,Q99439,Q9NUQ9,Q9P1F3,Q13045,Q00535,P46940,P60981,Q9NUL3,P62330,Q6IBS0,O75122,Q9UHB6,Q7Z460,Q9Y5K6 38 +Delamination 0.6701723634239036 0.7687952296065795 0.4420148812582902 1.0 0.8319541239751788 2 Q9Y5A9 1 +Snrna transport 0.6716177668355365 0.7686222039596496 0.4421176202727961 1.0 0.8319541239751788 3 Q9H814 1 +Lung morphogenesis 0.4313532234782581 0.7685572483578532 0.4421561930799731 1.0 0.8319541239751788 8 O00203,Q02750 2 +Histone mrna catabolic process 0.4601513244695933 0.7682091982623392 0.4423629096603982 1.0 0.8319541239751788 7 Q5TAX3 1 +Regulation of t cell activation 0.2878650027047408 0.7650943734989349 0.444215350042435 1.0 0.8332920088798482 38 P09429,O95999,P04083,O00203,Q06124,P51452,Q96J02,Q9NUQ9,P23396,O14617 10 +Methionine metabolic process 0.4888658228257329 0.7649704129519924 0.4442891630308503 1.0 0.8332920088798482 6 Q13126,Q9BV20 2 +Regulation of 3 utr mediated mrna stabilization 0.6690037978381627 0.7642978752889631 0.4446897512708214 1.0 0.8332920088798482 2 Q86W50 1 +Exocytic process 0.3442390707744432 0.7615591534308984 0.4463231613361778 1.0 0.8343187497464662 21 Q7Z6M1,Q9UNH7 2 +Cellular component morphogenesis 0.2359861175089133 0.7613500839549027 0.4464479933190581 1.0 0.8343187497464662 150 Q12955,Q06124,Q9UPY3,O43251,P16949,Q16512,O60678,Q6SZW1,Q02750,Q9BVA1,Q16527,O60271,Q9UNF0,Q9Y4F1,Q9Y2J2,Q9UQB8,Q13596,Q16555,P78559,Q13740,Q96PU5,P08238,P53990,P49841,P83731,Q13177,Q04837,Q8N8S7,P46934,Q00535,Q13614,P46821,Q9HCE1,Q9Y3D6,Q04917,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,O60749,O75122,Q6IBS0,Q7Z460,Q8N0X7 45 +Meiotic spindle organization 0.4080123608695357 0.7573778590051943 0.4488235170390777 1.0 0.8376749333044067 10 O95067,O14965,Q14674,P30153 4 +Positive regulation of plasma membrane bounded cell projection assembly 0.3087683884432696 0.7557691523175512 0.4497876148008282 1.0 0.8376749333044067 29 P42858,Q16658,O15144,Q15555,P50570,P42345,P49841,P27695,Q9H6U6,Q9UHD8,P07737,Q14195,Q6IBS0,P11233,Q06787 15 +Cellular response to corticosteroid stimulus 0.3832761811067922 0.7536448361705604 0.451062514081892 1.0 0.8377144031232928 13 P04083,P40818,P04150,P62826,O95831 5 +Nuclear transcribed mrna catabolic process 0.2663906160100963 0.7531092430034811 0.4513842705716713 1.0 0.8377144031232928 60 Q96Q15,Q96C86,Q5TAX3,Q969T7,P67809 5 +Negative regulation of protein containing complex assembly 0.282856510168947 0.7526639498279708 0.4516518783558942 1.0 0.8377144031232928 41 Q15691,Q99497,P47755,P35080,P16949,Q12792,P09429,P07737,Q9BTW9,P49841,Q9BPX3,P35241,Q9NUQ9,Q02790,Q13045,P58546,Q9UEY8,Q6IBS0,P04350 19 +Negative regulation of cellular catabolic process 0.2634211013459126 0.7526320309186663 0.4516710641046471 1.0 0.8377144031232928 98 Q16539,Q13614,Q96Q15,P16989,Q9H2J4,Q96HR8,Q14011,Q96KB5,P67809,Q9H814 10 +Positive regulation of interleukin 12 production 0.6670472012309034 0.7520878775917367 0.4519982135054459 1.0 0.8377144031232928 3 Q16539 1 +Positive regulation of intracellular transport 0.263460692754336 0.7503534718853686 0.4530418457424967 1.0 0.8377144031232928 78 P26038,O94766,Q9UBE0,Q12955,P15311,Q13131,P62826,Q16539,Q9Y282,Q9H6U6,Q14012,Q9H8V3,P17612,Q92688,P08238,P31751,P49841,O95817,O14737,P68036,P35241,Q13263,Q9UHD1,Q7Z6Z7,P62258,P46934,Q00535,Q13614,Q9NR31,Q9Y3D6,P19784,Q9C0E2,Q9UL25,Q9Y4C2,P06493 35 +Negative regulation of protein export from nucleus 0.6657158360554787 0.7472881519147154 0.4548896427636406 1.0 0.839172296471774 3 Q00535 1 +Negative regulation of inclusion body assembly 0.5226556802692679 0.7452712494965584 0.456107757973905 1.0 0.8398141867670244 5 P25685 1 +External encapsulating structure organization 0.2965471130332078 0.7452114317014028 0.45614391312801 1.0 0.8398141867670244 31 Q96AQ6,Q96AY3,Q92791 3 +Anatomical structure maturation 0.2855296261345533 0.7445930805520139 0.456517752214072 1.0 0.8398141867670244 38 Q5TAX3,Q8N2A8 2 +Response to steroid hormone 0.2618919645763409 0.7441678027593854 0.456774964075326 1.0 0.8398141867670244 75 Q9GZZ9,P06744,O75874,P46934,P04083,P0DP25,Q86X55,P07196,P04150,Q16512,O95831,P17174 12 +Immune response 0.2721109849450677 0.7440729472178436 0.4568323446714695 1.0 0.8398141867670244 224 Q9NVU0,Q13325,Q96FZ2,Q99497,P62942,Q14232,P98170,Q9UQ84,P28070,Q06124,P15311,Q96J02,P36915,P46108,P51617,Q16512,O43823,P09429,Q16539,P19474,Q6SZW1,Q9H4A3,Q9NR50,P04083,Q9Y3Z3,Q16543,Q9NUD5,O96028,Q9UN86,P07437,P14174,Q9UNH7,P23396,Q13740,Q13137,Q96C90,P08238,P06744,O95373,P46109,Q96FW1,P39019,Q13177,O00203,Q9NUQ9,Q8TDB6,Q01804,Q9Y5A9,P00491,Q6P179,O15347,P49770,O95999,Q96SB4,Q7Z739,Q13144,Q13283,Q13309,P51452,P13051,P25786 61 +Activation of nf kappab inducing kinase activity 0.663453111305881 0.7430304513067647 0.4574632444963518 1.0 0.8401471603714318 2 P51617 1 +Outer mitochondrial membrane organization 0.5214761753827787 0.7403967395690227 0.4590592966031532 1.0 0.8421975938954255 5 O14737,P07900 2 +Lipopolysaccharide mediated signaling pathway 0.4047406205090222 0.7402476809913932 0.4591497205857622 1.0 0.8421975938954255 10 Q16539,O95999,P14174 3 +Regulation of cell substrate adhesion 0.2771959550541699 0.7393993520329859 0.4596645356302331 1.0 0.8421983502995175 44 Q13630,Q00534,P46109,P49841,P42771,Q96AC1,Q9H6U6,P51452,Q13043,O75122,P46108,Q7Z460 12 +Production of molecular mediator of immune response 0.2849294039662186 0.7393424538774298 0.4596990762807511 1.0 0.8421983502995175 38 P06744,O95999,Q9UQ84,Q9Y3Z3,O96028,P13051,P14174,Q16512 8 +Regulation of protein stability 0.2459301390998561 0.7393045657376677 0.4597220774982515 1.0 0.8421983502995175 122 Q99497,Q9H2J4,Q92995,Q13043,P35080,Q13526,O95429,P83436,P19474,Q96K76,Q16543,Q9BXJ9,P07737,Q9Y4R8,Q5HYI8,P42858,Q96PU5,P08238,O43670,Q96RU2,O95817,P40818,Q9UHD1,P62081,Q9UNS2,P54725,O94966 27 +Exocytosis 0.26287756093487 0.7372787952739919 0.4609528245829095 1.0 0.8433530445879932 80 Q9UN37,Q7Z6M1,P04083,Q92905,Q16512,Q92783,Q4J6C6,Q9UNH7,Q12765,O75122,P35080,P0DP25,Q15019,O95721 14 +Brainstem development 0.6617002629272608 0.736347930712981 0.4615189838644193 1.0 0.8436863953505969 2 P31939 1 +Positive regulation of kinase activity 0.2611100588328064 0.73517061375127 0.4622355934167146 1.0 0.8437222337120751 75 Q96A49,Q99497,Q99570,P36507,Q13043,P51617,Q16512,Q02750,Q9H4A3,Q96AC1,Q14012,Q9Y4R8,P23396,P14174,Q05639,Q86Y37,Q9UNI6,P08238,Q96M27,O75832,Q00535,O95999,P0DP25,Q9NQ88 24 +Positive regulation of amyloid precursor protein catabolic process 0.4529695841314057 0.7345892181119361 0.4625897063501525 1.0 0.8437718163420601 7 O75116,Q13492,Q96P70,Q96S59,P49840 5 +Negative regulation of sister chromatid cohesion 0.5477609398349752 0.7328413313404694 0.4636552094006132 1.0 0.8447941625800599 4 Q14674 1 +Negative regulation of blood pressure 0.5477430790922732 0.732770564980043 0.4636983769966045 1.0 0.8447941625800599 4 P42785 1 +Ventral spinal cord development 0.5195906432748351 0.7326187859211999 0.4637909700208187 1.0 0.8447941625800599 5 P26367,Q6Y7W6,Q9ULW3,Q14203 4 +Intestinal epithelial cell differentiation 0.660531697341527 0.7319020943299991 0.4642283277977341 1.0 0.8448904298295592 2 Q9NQ88 1 +Intestinal epithelial cell development 0.660531697341527 0.7319020943299991 0.4642283277977341 1.0 0.8448904298295592 2 Q9NQ88 1 +Negative regulation of intracellular signal transduction 0.2570977422644607 0.7316320012333064 0.4643932104202348 1.0 0.8449572296688347 108 Q8IV63,Q99497,P30153,P30086,Q96J02,Q13526,Q96B36,P16949,Q16539,Q96K76,P31689,Q53EL6,O95881,P14174,Q96KB5,P78318,Q14152,P16989,P49841,P04792,O75832,Q9NUQ9,Q9UHD1,Q13546,P49427,P43034,P51452 27 +Regulation of nik nf kappab signaling 0.3528788945556893 0.730995111038685 0.4647821391615592 1.0 0.8454315290709156 16 Q9NYB0,P15311,Q53EL6,P51617,P23396 5 +Innate immune response 0.2346023459196379 0.7300060315460107 0.4653864977983399 1.0 0.8458306571509946 131 Q9NVU0,Q13325,P98170,Q06124,Q96J02,P46108,P51617,Q16512,O43823,P09429,Q6SZW1,P19474,P04083,Q9Y3Z3,Q16543,Q9NUD5,Q9UN86,P07437,P14174,Q13137,Q96C90,P08238,O95373,P39019,Q13177,Q8TDB6,Q01804,Q9Y5A9,O15347,O95999,Q9UII4,Q96SB4,Q7Z739,Q13283,Q13309 35 +Deoxyribonucleoside triphosphate biosynthetic process 0.6607247223845674 0.7293635485724677 0.4657793089667876 1.0 0.8459344914966108 3 P55263,P23919 2 +Viral translational termination reinitiation 0.4807660797907791 0.729282463687181 0.4658288969830058 1.0 0.8459344914966108 6 O75821,O15371,Q14152,Q9Y262 4 +Ephrin receptor signaling pathway 0.4100503906557883 0.728537964695369 0.4662843374838323 1.0 0.8461669798879282 9 P46108,Q16512 2 +Regulation of t cell proliferation 0.3450608296209371 0.7284441864694033 0.4663417229873852 1.0 0.8461669798879282 19 P09429,P04083,Q96J02 3 +Cellular response to radiation 0.2700227527860144 0.7269734787041091 0.4672422026405654 1.0 0.8463982189412032 52 Q16539,Q13535,Q9H1E3,Q96KB5,P46934,O60921 6 +Muscle cell apoptotic process 0.3498752308108487 0.7265506465312048 0.4675012711241066 1.0 0.8463982189412032 17 P42771,Q53EL6,Q9NQ88,O95817 4 +Regulation of cytoskeleton organization 0.2326554948396911 0.7260479137548157 0.4678093981406934 1.0 0.8463982189412032 148 Q16658,Q15691,O15144,P47755,P42345,O75351,P15311,Q13131,Q14203,P35080,Q9Y5K6,P46108,P16949,Q16512,O95429,Q8IX90,Q9UHV9,Q9NZZ3,Q9Y281,Q9H6U6,Q96AC1,P07737,Q9H8V3,Q9UQB8,P78559,Q8TD16,P23396,Q14204,O60504,P48681,P49841,P36405,O75116,Q13177,Q9BPX3,P60983,P35241,Q14019,Q9NUQ9,Q02790,Q13045,Q9HD42,Q00535,P46821,P46940,Q15555,P60981,Q9NUL3,P43034,P62330,Q6IBS0,O75122,Q9UHB6,Q6UVJ0,Q7Z460,P04350 56 +Regulation of leukocyte chemotaxis 0.3469483027628124 0.7236479612729427 0.4692818886704764 1.0 0.8463982189412032 18 P09429,Q9H4A3,P30046,O95747 4 +Response to ketone 0.2782324350515729 0.7227957728380109 0.4698053647670983 1.0 0.8463982189412032 42 P06744,Q96C86,Q13126,P07196,P04150,P49321,O43823,P0DP25,O95831 9 +Regulation of protein kinase activity 0.2486685767048859 0.7218031325069114 0.4704155232748319 1.0 0.8463982189412032 118 Q96A49,Q99497,P36507,P42771,Q13043,Q96B36,P51617,Q16512,Q02750,Q9H4A3,Q16543,Q96AC1,P31689,Q53EL6,Q9UNH7,Q14012,Q9Y4R8,P14174,P23396,P42858,Q86Y37,P08238,O95373,Q96M27,P04792,O75832,Q9UHD1,Q00535,Q96SZ6,Q9P287,O95067,P51452,P0DP25 33 +Hepatocyte growth factor receptor signaling pathway 0.5169447521663741 0.7217347548656979 0.4704575699086604 1.0 0.8463982189412032 5 P16949 1 +Organelle fusion 0.2700312498137923 0.7215342485639497 0.4705808767810722 1.0 0.8463982189412032 51 Q8N2A8,Q96E52,Q8WUH2 3 +Nuclear membrane reassembly 0.393314233136667 0.7204311553566621 0.4712595733266025 1.0 0.8463982189412032 11 Q9NZZ3,Q9HD42 2 +Negative regulation of leukocyte chemotaxis 0.6581441236914256 0.7201397416192233 0.4714389606197771 1.0 0.8463982189412032 3 P30046 1 +Telomere maintenance 0.2568540434849984 0.7201037569018333 0.471461114558737 1.0 0.8463982189412032 69 Q96Q15,Q9UQ84,P35244,Q9NYB0,Q96HR8,O60921 6 +Negative regulation of wound healing 0.4214450156229313 0.7192985606696388 0.4719569825624532 1.0 0.8463982189412032 8 O75122,P46108 2 +Positive regulation of actin filament depolymerization 0.6578153903655317 0.7189669561005596 0.4721612797805767 1.0 0.8463982189412032 3 P60981 1 +Regulation of cell morphogenesis 0.2572742545258022 0.718446007616717 0.4724823276685881 1.0 0.8463982189412032 70 Q9HCE1,P04083,Q96AC1,Q9UEE9,Q9UIW2,Q9UQB8,P46108,Q96PU5 8 +Cell cycle phase transition 0.2459280882174912 0.71829563963815 0.4725750181519932 1.0 0.8463982189412032 172 Q93034,Q9UN37,O43768,O75351,P33981,O00716,P42771,Q06124,P15927,P24941,P49321,O43823,Q99640,Q16539,Q96K76,Q00534,Q15645,Q9NVH2,P04083,Q16763,Q13535,Q9NWV8,Q14674,Q9P258,Q9UNS1,Q9Y6G9,O60921,Q86Y37,Q07864,P31350,O43670,Q969U7,Q96RU2,P83731,Q04637,P68036,P61289,Q9NZJ0,Q9UL46,Q00535,P49427,Q9BXW9,O95905,Q9UPP1,Q96DY7,O95067,Q13309,O75122,O14965,Q6UVJ0,P0DP25,Q7Z460 52 +Viral release from host cell 0.3484576614003439 0.7178068913780432 0.4728763636330022 1.0 0.8463982189412032 17 Q9NZZ3,P53990,Q9HD42 3 +Lymphocyte homeostasis 0.3926915588917927 0.7171413277313228 0.4732868974724351 1.0 0.8463982189412032 11 O95067,Q16512,O95999 3 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.6572180011689033 0.71683700478835 0.4734746756506671 1.0 0.8463982189412032 3 P33316,P04818 2 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.6572180011689033 0.71683700478835 0.4734746756506671 1.0 0.8463982189412032 3 P33316,P04818 2 +Dtmp metabolic process 0.6572180011689033 0.71683700478835 0.4734746756506671 1.0 0.8463982189412032 3 P33316,P04818 2 +Regulation of intracellular protein transport 0.2598461559395587 0.7162800304092549 0.4738184549319717 1.0 0.8466823678263914 76 Q99497,O14980,O94766,Q9UBE0,Q12955,Q06124,P62826,O95429,Q16539,Q9Y282,Q9H6U6,Q14012,P17612,Q92688,P08238,P31751,P49841,Q8IWJ2,O95817,O14737,P68036,Q13263,Q9UHD1,Q7Z6Z7,P62258,Q00535,Q9NR31,Q9Y3D6,P19784,Q9C0E2,Q9Y4C2,P06493 32 +Positive regulation of organelle organization 0.2419213938410007 0.715773740645581 0.4741310693539895 1.0 0.846778539551186 165 O15144,Q15691,Q99497,P42345,Q9C0E8,O75351,Q8N2A8,O15260,Q15047,Q14203,P24941,P35080,Q96HR8,Q16512,O95429,Q9UHV9,P04083,P78371,P27695,Q9H6U6,Q13535,Q96AC1,P07737,Q14674,Q9UN86,P13010,Q9UQB8,P23396,Q13137,P39748,P42858,O60504,P78356,P31751,P48681,P49841,P36405,Q9BPX3,O14737,Q04837,Q15042,P11233,Q00535,P46821,Q15555,P60981,Q9Y3D6,Q9BXS6,P62330,Q13283,O14965,Q6UVJ0,Q7Z460 53 +Phosphatidylinositol biosynthetic process 0.3223935743480146 0.7153608516846748 0.4743860962625197 1.0 0.846778539551186 25 Q13614,P42356,P78356,Q96Q15,Q8NEB9,Q9H490,Q01968,Q8NCE2 8 +Endosome to lysosome transport 0.3337869736295406 0.7139698101846226 0.4752458477388357 1.0 0.8472185476267472 22 Q96L92,O75351,Q8TDB6,Q86VS8,O14617,P20645,Q8WUH2 7 +Regulation of protein polyubiquitination 0.420259748537474 0.7134487343662285 0.4755681254835746 1.0 0.8472185476267472 8 P98170 1 +Myeloid cell homeostasis 0.270959108265665 0.7132951244414044 0.4756631538390172 1.0 0.8472185476267472 47 Q9GZZ9,Q16539,P09429,Q00534,P06744,P04083,O43251,Q6NYC1,P08708 9 +Sequestering of actin monomers 0.6555652936021175 0.7130912402578841 0.4757892996532438 1.0 0.8472185476267472 2 Q6IBS0 1 +Actin modification 0.6555652936021152 0.7130912402578755 0.4757892996532491 1.0 0.8472185476267472 2 Q86TU7 1 +Negative regulation of viral life cycle 0.6560490940970161 0.7126741824527502 0.4760473959083968 1.0 0.847220419500041 3 Q14258,O60493 2 +Negative regulation of viral entry into host cell 0.6560490940970161 0.7126741824527502 0.4760473959083968 1.0 0.847220419500041 3 Q14258,O60493 2 +Regulation of leukocyte migration 0.2975875103032952 0.7100359577227874 0.4776818383410723 1.0 0.8488008996379927 30 P09429,P46109,O95747,P04083,P46108,P30046 6 +Regulation of long term synaptic depression 0.6546888694127999 0.7097860954499676 0.4778367928635605 1.0 0.8488008996379927 2 Q9NUL3 1 +Nucleoside diphosphate metabolic process 0.270150542176207 0.7091598708034238 0.4782252729260803 1.0 0.8492621226101081 48 P08237,P00558,Q13131,P23919,P85037,Q9BRR6,P14618,P51570,P15531,P06744,P11172,P00338,P31350,P36871,Q9UDY2,Q01813,P22392,P23921,P60174,P18669,Q9UKK9,Q9NQ88 22 +Negative regulation of cell matrix adhesion 0.4191376403071945 0.7079195944466025 0.4789951907917951 1.0 0.8493852671936979 8 P42771,O75122,Q9H6U6 3 +Activation of immune response 0.2722557388522765 0.7075634232518289 0.4792164137652395 1.0 0.8493852671936979 45 P09429,P49770,P17931,P46109,Q14232,O95999,Q9H4A3,Q9NR50,Q13177,Q9NUD5,P15311,Q13144,P51452,P13010,P78527,P23396,Q16512,P07900 18 +Necroptotic signaling pathway 0.6538124452234996 0.706485365403536 0.4798863505043493 1.0 0.8493852671936979 2 Q13546 1 +Cellular response to hyperoxia 0.6538124452234904 0.7064853654034999 0.4798863505043718 1.0 0.8493852671936979 2 O95352 1 +Dna unwinding involved in dna replication 0.3466135812084007 0.7064654477882074 0.4798987326978166 1.0 0.8493852671936979 17 Q9Y248,Q9BRT9,P46063,P49736,Q04837,Q9BRX5,P25205,P33991 8 +Synaptic vesicle transport 0.390564203781189 0.7059258024514711 0.4802342805751873 1.0 0.8493852671936979 11 O00203,O14617,Q92572 3 +Organelle transport along microtubule 0.2914024612167058 0.7038916058356752 0.4815002793773701 1.0 0.8509095284237336 31 P46821,Q9Y496,Q9Y678,P27695,O00203,P43034,P07196,Q9NZ32,Q8TD16,O14617,Q92572,P42858 12 +Regulation of exocytosis 0.271695975732216 0.7023522342330573 0.4824595257446717 1.0 0.8515055404843043 45 Q9UN37,P49841,O75351,P04083,Q92783,Q4J6C6,P35080,O75122,Q15042,P0DP25,Q15019,Q00535 12 +Gtp metabolic process 0.3820701213660383 0.7015111270427787 0.4829840930266103 1.0 0.8519751515203144 12 P15531,P22392 2 +Positive regulation of substrate adhesion dependent cell spreading 0.3653259941563012 0.7006215232860904 0.483539242712024 1.0 0.8522702374218347 14 Q96AC1,P46108 2 +Negative regulation of cilium assembly 0.6525423728813504 0.7002247610791728 0.4837869504266807 1.0 0.8524789032912802 3 P27816,P50570 2 +Rna phosphodiester bond hydrolysis 0.253802544232907 0.6997129057685515 0.4841066150667785 1.0 0.852586376307829 67 Q96C86,Q9UQ84,Q8N2A8,Q9BQG2 4 +Cell morphogenesis involved in neuron differentiation 0.2566484133817542 0.6969496005285186 0.4858343352543177 1.0 0.8543516587319857 104 Q12955,Q06124,O43251,P16949,Q16512,O60678,Q6SZW1,Q02750,Q9BVA1,O95487,Q9Y4F1,Q9UQB8,P78559,Q16555,Q13740,Q96PU5,P08238,P53990,P49841,P83731,Q13177,Q8N8S7,P46934,Q00535,P46821,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,Q8N0X7 32 +Rna destabilization 0.2679188106949786 0.6960734194944513 0.4863828516760287 1.0 0.8543516587319857 50 Q96C86,Q969T7,Q5TAX3,P67809 4 +Negative regulation of cytokine production 0.3059248663078711 0.696038048071988 0.4864050023090325 1.0 0.8543516587319857 28 P09429,P49591,P04083,P15311,Q9UPY3,Q53EL6,Q96J02,O43823,P30740 9 +Mammalian oogenesis stage 0.6508910312591343 0.6955152706814948 0.4867324445891008 1.0 0.8546010004958414 2 P62753 1 +Central nervous system neuron axonogenesis 0.5104186864269509 0.6950484855764053 0.4870249166632128 1.0 0.8546010004958414 5 P43034,P08238 2 +Ubiquitin recycling 0.5381467407190919 0.6949836823176939 0.4870655277401208 1.0 0.8546010004958414 4 Q16763,Q9Y263,P61086 3 +Regulation of cell development 0.2599052895913953 0.6930426638651528 0.4882827777627034 1.0 0.8560532103754631 92 P42345,Q9UPY3,P46108,P55209,Q02750,P27695,Q86VS8,Q96AC1,Q96G23,Q9P258,P13010,Q9UQB8,P53990,P46109,P49841,P39019,O43379,Q16706,Q00535,P46821,Q9Y5A9,Q9NUL3,Q04917,P43034,Q9UIW2,P07196,Q9P265,Q6IBS0,O14965,Q8N0X7 30 +Positive regulation of mrna metabolic process 0.2554471092877486 0.6918088457276088 0.4890573808235614 1.0 0.8567521236846174 71 Q96C86,Q5TAX3,Q969T7,Q14011,P67809,P98179 6 +Dna replication initiation 0.3231510094607582 0.6917866283607972 0.4890713351676601 1.0 0.8567521236846174 24 P49427,P49642,Q7L590,O43913,P49736,O95251,Q9UBD5,P25205,P24941,P49643,P33991,Q9UFC0 12 +Positive regulation of amyloid beta formation 0.5372698041508339 0.6915549519604675 0.4892168598888164 1.0 0.8567541741626328 4 O75116,P49840,Q13492 3 +Positive regulation of cell morphogenesis involved in differentiation 0.3145946149347255 0.6913709689094686 0.4893324432224382 1.0 0.8567541741626328 26 Q96AC1,P46108,Q9UQB8 3 +Positive regulation of cyclin dependent protein kinase activity 0.536735468240154 0.6894678338937645 0.490528908524162 1.0 0.8583930355697573 4 O75832 1 +Regulation of skeletal muscle tissue development 0.4428370716481565 0.6876815471886467 0.4916533427783109 1.0 0.8589925352755435 7 P16989 1 +Fibroblast growth factor receptor signaling pathway 0.4427184082946627 0.6871361672188302 0.4919969248175331 1.0 0.8591374114959413 7 Q06124,Q8NEM2,P46109 3 +Positive regulation of translational initiation 0.3708679375655158 0.6849391362046243 0.4933823285780958 1.0 0.8593541580216452 13 Q9Y5A9,P42345,Q7Z739,Q13144,O75794 5 +Cellular response to peptide hormone stimulus 0.2542507567330663 0.684503168614995 0.4936574892035588 1.0 0.8593541580216452 70 Q96A49,Q5VZ89,P61981,P42224,Q06124,Q9H1E3,P46108,Q13243,P27695,P07741,P14618,Q9UQB8,Q92572,P78356,P31751,P49841,O75116,O43865,O60343,P78527,Q9Y5X3,P43490,P17174,P46821,O60763,Q9BSK2 26 +Regulation of synapse assembly 0.401391169148224 0.6844589441804342 0.4936854060115245 1.0 0.8593541580216452 9 Q96HC4,Q04637,Q9NUL3,Q9Y4F1 4 +Peptidyl cysteine modification 0.4138644074648148 0.6820574386311377 0.4952026317483482 1.0 0.8595224621520271 8 Q96JJ7,P08397 2 +Regulation of cation transmembrane transport 0.2654370664313434 0.6819442394964831 0.4952742102373701 1.0 0.8595224621520271 52 P42858,Q99497,P62942,Q9H4A3,O95747,P0DP25,P27695,Q00535,P28161,Q04917,Q12955,Q9UHD1,P17612,P46934,Q96PU5 15 +Cellular process involved in reproduction in multicellular organism 0.264852023283755 0.6818295152075975 0.495346758755393 1.0 0.8595224621520271 53 Q9Y5A9,P30153,P42345,Q15645,Q5TAX3,Q8N2A8,Q96SB4,P33981,O95067,Q9BQA1,P43034,Q9GZP4,P62826,O14965,A0AVF1,O60879,Q92879 17 +Positive regulation of dendrite morphogenesis 0.385913475980037 0.6815421424847413 0.495528510355451 1.0 0.8596115632271402 11 Q9UQB8,P43034,Q9UL25,Q9NUL3 4 +Cellular response to peptide 0.2578166025563916 0.675841278111512 0.4991414238386569 1.0 0.8647411999853944 81 Q5VZ89,Q06124,Q9H1E3,P46108,Q13243,Q9NZZ3,Q9UNS1,Q9UNH7,Q9UQB8,Q92572,P78356,P49841,O43865,O60343,Q9Y5X3,P43490,P17174,Q00535,P46821,O60763 20 +Sex differentiation 0.2741302020690263 0.6746765231343885 0.4998813033489269 1.0 0.8653407436124281 41 P49770,P46109,P16989,O75874,Q92674,Q15392,P49321 7 +Histone arginine methylation 0.6451610880042242 0.6742185311170391 0.5001723899042048 1.0 0.8653901297240205 3 Q86X55 1 +Embryo development ending in birth or egg hatching 0.2251297592472342 0.6728935515898034 0.5010150149083801 1.0 0.8661660053176086 141 O43772,Q92541,P20290,P49321,P67809,Q96AY3,Q02750,Q96EK5,P07737,O60921,P06744,P16989,Q6DKJ4,Q01968,P62081,P55199,Q9BRT9,Q9UNS2,O95067,O95747 20 +Regulation of fatty acid transport 0.4676230810578497 0.6721590030066651 0.5014824773357067 1.0 0.8666862215083686 6 P14174,P31751 2 +Response to peptide 0.2525634770737139 0.6718640666285808 0.5016702380882372 1.0 0.8666862215083686 108 Q96A49,Q5VZ89,Q14232,Q06124,Q9Y266,Q9H1E3,P46108,Q16539,Q13243,Q9NR50,P04083,Q9NZZ3,Q9UNS1,Q9UNH7,Q9UQB8,Q92572,P78356,P49841,O43865,O60343,Q9Y5X3,P43490,Q00535,P17174,P46821,O60763,P49770,Q13144,P07196 29 +Auditory receptor cell development 0.4675399459316247 0.6718010674436311 0.5017103491013251 1.0 0.8666862215083686 6 Q9Y6M7,O95487 2 +Regulation of muscle organ development 0.4116470754416291 0.6712451852446458 0.5020643478524218 1.0 0.8669798273774044 8 P16989 1 +Negative regulation of tor signaling 0.4392243396061631 0.6711211527169589 0.5021433526891581 1.0 0.8669798273774044 7 Q96EB6,P49815,Q13131,Q96B36,P49840 5 +Aspartate family amino acid biosynthetic process 0.3762901031554123 0.6707530178627077 0.5023778817907645 1.0 0.8671576320410367 12 P11586,Q9NRN7,Q13126,Q9BV20,P17174 5 +Regulation of protein depolymerization 0.279617131560996 0.6702042315670057 0.5027276067280577 1.0 0.8675341318197268 35 Q7Z460,P58546,P46821,P48681,P47755,P60981,Q9Y281,Q9BPX3,Q9UEY8,P35241,Q6IBS0,O75122,P78559,Q13045,Q12792,Q9UHB6 16 +Torc2 signaling 0.6436869384252857 0.6690581597620097 0.5034583785021371 1.0 0.8681134269123955 3 Q96A49 1 +Positive regulation of canonical wnt signaling pathway 0.3403196991037059 0.6680558557270696 0.50409793889335 1.0 0.8687353047330075 17 Q13526,Q9H4A3,P40818,P98170 4 +Endothelial cell migration 0.2745065851110147 0.6676670006241046 0.5043461788855006 1.0 0.8687353047330075 40 P09429,Q16539,P04083,P42785,P04792 5 +Negative regulation of mrna metabolic process 0.2656932453393111 0.666847723428218 0.5048694056328031 1.0 0.86915518053824 48 Q16539,P67809,P16989 3 +Vesicle mediated transport in synapse 0.277498364738875 0.6668070078100954 0.5048954158917751 1.0 0.86915518053824 37 P49841,O00203,Q4J6C6,P35080,Q15042,P0DP25,O14617,O95721 8 +Regulation of dna templated transcription initiation 0.3421400844510522 0.6660470324385643 0.5053810386837188 1.0 0.86915518053824 16 P09429,O60244,P62333,Q86VP6 4 +Osteoclast differentiation 0.3752990033964524 0.6655116626774065 0.5057232865471404 1.0 0.8693067827443609 12 Q16539 1 +Lung alveolus development 0.6427110721589304 0.6650733500701427 0.5060035791182296 1.0 0.8693067827443609 2 Q16706 1 +Negative regulation of protein targeting to mitochondrion 0.6424740863133482 0.6648210790792555 0.5061649386702196 1.0 0.8693067827443609 3 O95817 1 +Myotube differentiation 0.3396815233806212 0.6641884930663363 0.5065696773132116 1.0 0.8693067827443609 17 Q16539,Q8IV08 2 +Positive regulation of organelle assembly 0.3015051965871609 0.6635061158960548 0.5070064638297613 1.0 0.8693067827443609 28 Q16658,P26038,A5YKK6,P78356,Q15555,P49841,O75351,P27695,Q9BPX3,Q9UHD8,Q13283,Q9UN86,Q6UVJ0,Q15042,P42858 15 +Nuclear body organization 0.6417299824663919 0.6622254441165755 0.5078267498912123 1.0 0.8696105453799107 3 Q15637,Q8NC51 2 +Centrosome duplication 0.3225787401958334 0.6618616755760333 0.5080598750786549 1.0 0.8696105453799107 23 P41208,Q9NZZ3,O75351,O43379,Q9UHD1,Q6UVJ0,Q9HD42 7 +Cell part morphogenesis 0.2261677353640729 0.6609660345257348 0.5086340960007258 1.0 0.8696221750696138 134 Q12955,Q06124,Q9UPY3,O43251,P16949,Q16512,O60678,Q6SZW1,Q02750,Q9BVA1,O60271,Q9UNF0,Q9Y4F1,Q9Y2J2,Q9UQB8,Q13596,Q16555,P78559,Q13740,Q96PU5,P08238,P53990,P49841,P83731,Q13177,Q04837,Q8N8S7,P46934,Q00535,P46821,Q9HCE1,Q9Y3D6,Q04917,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,O60749,Q6IBS0,Q8N0X7 41 +Motor neuron apoptotic process 0.6415425065731859 0.660758715709885 0.508767062457077 1.0 0.8696221750696138 2 P49327 1 +Cerebral cortex development 0.2911939194657366 0.6605913015565898 0.5088744488646788 1.0 0.8696221750696138 30 P46109,P49841,O43379,P19784,P43034,O43776,P07196,P31939,P46108,Q96P11,Q00535 11 +Pattern recognition receptor signaling pathway 0.2776399919799523 0.6605430043904262 0.508905430885195 1.0 0.8696221750696138 36 P09429,Q6SZW1,Q01804,P98170,O00203,Q96J02 6 +B cell activation 0.2736709494857192 0.6603942286403266 0.5090008748566985 1.0 0.8696221750696138 40 O15347,Q9UQ84,O96028,P13051,P78318 5 +Regulation of cellular amine metabolic process 0.4368453596222797 0.6602669733538779 0.5090825202660254 1.0 0.8696221750696138 7 O14874,Q6QHF9 2 +Imp salvage 0.6408533021624764 0.6591711643997301 0.5097858614744721 1.0 0.8700597631680005 3 Q01433,P07741 2 +Gmp salvage 0.6408533021624739 0.6591711643997211 0.5097858614744779 1.0 0.8700597631680005 3 P55263,P07741 2 +Roof of mouth development 0.4361766706408267 0.6572235424737044 0.5110371899695076 1.0 0.870888424942561 7 Q92688 1 +Negative regulation of protein localization 0.270873989234542 0.6568394634288349 0.5112841463745745 1.0 0.870888424942561 42 Q99497,Q16850,P49841,P20290,O95817,Q00535,Q06124,P31689,Q9UHD1,P78559,O95429,Q96PU5 12 +Eye photoreceptor cell differentiation 0.5009635605657298 0.656817294681918 0.5112984024104614 1.0 0.870888424942561 5 Q15555 1 +Amyloid precursor protein catabolic process 0.3360659443302876 0.6563261569052599 0.5116142911680641 1.0 0.870888424942561 18 Q15392,P62942 2 +Response to estradiol 0.3383451841957992 0.6561072844050123 0.5117550978393104 1.0 0.870888424942561 17 P06744,P04083,O95831 3 +Sodium ion transmembrane transport 0.3212669479596132 0.6532362428187782 0.5136039884291339 1.0 0.8720569468926728 23 Q9H4A3,Q12955,O95747,P46934,Q96PU5 5 +Regulation of vesicle fusion 0.4999429384660802 0.6527231387515803 0.5139347825158909 1.0 0.8720569468926728 5 O60343,P04083 2 +Telomere organization 0.2512432081175079 0.651091410241027 0.514987481076739 1.0 0.8720569468926728 70 Q96Q15,Q9UQ84,P35244,Q9NYB0,Q96HR8,O60921 6 +Renal sodium ion transport 0.6386210926088343 0.6500108897886615 0.5156851874351442 1.0 0.8720569468926728 2 Q9UNF1 1 +Renal absorption 0.6386210926088343 0.6500108897886615 0.5156851874351442 1.0 0.8720569468926728 2 Q9UNF1 1 +Extracellular transport 0.6386210926088272 0.6500108897886344 0.5156851874351618 1.0 0.8720569468926728 2 Q99816 1 +Bile acid secretion 0.6386210926088253 0.6500108897886285 0.5156851874351656 1.0 0.8720569468926728 2 Q13131 1 +Regulation of lymphocyte activation 0.2588992376633294 0.6493743577370725 0.516096434085755 1.0 0.8720569468926728 57 P09429,Q9NUQ9,O15347,P00491,O95999,P04083,O00203,Q06124,P51452,Q96J02,O96028,P14174,P23396,Q16512,O14617 15 +T cell activation 0.2554991946394824 0.6486761398244631 0.5165477298849583 1.0 0.8720569468926728 61 P17931,P62942,P42345,Q06124,Q96J02,Q6NYC1,P09429,P24390,Q00534,P04083,P23396,Q5HYI8,P17812,O00203,Q9NUQ9,O14617,P00491,O95999,Q9BXW9,Q9NQT8,P62753,P51452 22 +Positive regulation of protein phosphorylation 0.2434373860417363 0.6485837090708665 0.5166074881801066 1.0 0.8720569468926728 118 Q96A49,Q99497,P51114,P36507,P33981,Q06124,Q13043,P35080,Q13526,Q93062,P51617,Q16512,O95429,Q02750,Q9H4A3,Q9NYB0,Q96AC1,Q14012,Q9Y4R8,P14174,P23396,Q86Y37,P08238,P46109,P31751,Q96M27,Q13177,O75832,Q13546,Q00535,P10398,P0DP25 32 +Intracellular distribution of mitochondria 0.638036809815968 0.6478680578572453 0.5170702919557026 1.0 0.8720569468926728 2 O75153 1 +Integrated stress response signaling 0.461785901723775 0.6471395172136545 0.5175416516439786 1.0 0.8720569468926728 6 Q96E52 1 +Positive regulation of nf kappab transcription factor activity 0.308267021799961 0.6469791966525743 0.5176454075474766 1.0 0.8720569468926728 26 P19474,O95999,Q9NYB0,P60900,P23396,Q13546 6 +Response to extracellular stimulus 0.2558038795539285 0.6468450843344706 0.5177322103260029 1.0 0.8720569468926728 94 Q9H773,Q9UMX5,Q96E52 3 +Negative regulation of golgi to plasma membrane protein transport 0.6370543541788394 0.6459844228062128 0.5182894435824299 1.0 0.8720569468926728 3 P41240,Q9HD26 2 +Positive regulation of establishment of protein localization to telomere 0.3936870172447573 0.6457438409248135 0.5184452631784564 1.0 0.8720569468926728 9 P17987,P50991,P78371,P40227,P48643,P49368 6 +Establishment of protein localization to telomere 0.3936870172447573 0.6457438409248135 0.5184452631784564 1.0 0.8720569468926728 9 P17987,P50991,P78371,P40227,P48643,P49368 6 +Regulation of establishment of protein localization to chromosome 0.3936870172447573 0.6457438409248135 0.5184452631784564 1.0 0.8720569468926728 9 P17987,P50991,P78371,P40227,P48643,P49368 6 +Glandular epithelial cell development 0.461251037439953 0.6448586601155469 0.5190187836918678 1.0 0.8723011402478829 6 Q00534 1 +Immune system development 0.2434779580583297 0.6440802723801918 0.5195233821399472 1.0 0.8723011402478829 176 Q9GZZ9,Q96FZ2,P17931,Q9HCE5,Q9UQ84,Q9NPH0,O95251,Q06124,Q9Y4E6,Q9GZS3,Q13043,Q96J02,Q9UBL3,O43251,Q6NYC1,Q16512,P55327,P09429,Q16539,P24390,Q00534,Q02750,P04083,Q9Y3Z3,O96028,Q5HYI8,Q96AQ6,P46109,P39019,O00203,Q9GZP4,Q99439,O14617,Q13546,P18858,O00625,Q9Y5A9,P00491,O15347,Q9BXW9,Q9Y4B6,O95067,P43034,Q96PZ0,Q6NXE6,P13051,Q04760 47 +Fructose metabolic process 0.5247003800058603 0.6428967026478815 0.5202911291339709 1.0 0.8725311141725391 4 P04075,P15121,Q00796 3 +Aromatic amino acid family metabolic process 0.4606345293942371 0.6422321494027232 0.520722461575506 1.0 0.8725311141725391 6 P61457,P16930 2 +Aldehyde biosynthetic process 0.6358854471069477 0.6419430748632495 0.5209101446884836 1.0 0.8725311141725391 3 P29401,O00764 2 +Lipid export from cell 0.4968729274605181 0.640448348908978 0.521881158588076 1.0 0.872782167784953 5 Q06124 1 +Dopamine transport 0.6359918200409117 0.6403860990617395 0.521921617932082 1.0 0.872782167784953 2 Q99497 1 +Monoamine transport 0.6359918200409117 0.6403860990617395 0.521921617932082 1.0 0.872782167784953 2 Q99497 1 +Catecholamine uptake involved in synaptic transmission 0.6359918200409117 0.6403860990617395 0.521921617932082 1.0 0.872782167784953 2 Q99497 1 +Catecholamine uptake 0.6359918200409117 0.6403860990617395 0.521921617932082 1.0 0.872782167784953 2 Q99497 1 +Rna interference 0.4050878841888561 0.6394929629370041 0.5225022900929792 1.0 0.8733257976127972 8 Q15631,Q9UPY3,Q9HAV4,Q99598 4 +Positive regulation of cell differentiation 0.2296297190202196 0.6334921438648845 0.5264123095158049 1.0 0.8760349886928371 130 Q96A49,P17931,O15144,O00299,P42345,O95251,Q9UPY3,Q13043,P46108,P09429,Q16539,P55209,Q02750,P04083,P27695,Q96AC1,O60271,P13010,Q14012,Q9UQB8,P08238,P53990,P46109,Q86TU7,P49841,O43379,O00203,Q04637,Q9GZP4,Q16706,P22392,Q99873,O14617,Q13546,P46821,P00491,Q9UQ80,Q9NUL3,P43034,Q9UIW2,Q86X55,P07196,Q6IBS0,O14965 44 +Polyol catabolic process 0.4304966225302865 0.6315093858462356 0.5277075142188239 1.0 0.8769195479890357 7 Q13614 1 +Acid secretion 0.6326709526592609 0.6308693687419263 0.5281259416712882 1.0 0.8769195479890357 3 Q13131,O14745 2 +Methionine biosynthetic process 0.4944476556141886 0.6307952697978951 0.5281743966562247 1.0 0.8769195479890357 5 Q13126,Q9BV20 2 +Sulfur amino acid biosynthetic process 0.4944476556141886 0.6307952697978951 0.5281743966562247 1.0 0.8769195479890357 5 Q13126,Q9BV20 2 +Positive regulation of lymphocyte chemotaxis 0.6317725776780573 0.6277851747483545 0.5301446792549456 1.0 0.8769195479890357 3 O95747 1 +Regulation of lymphocyte chemotaxis 0.6317725776780573 0.6277851747483545 0.5301446792549456 1.0 0.8769195479890357 3 O95747 1 +Regulation of t cell chemotaxis 0.6317725776780573 0.6277851747483545 0.5301446792549456 1.0 0.8769195479890357 3 O95747 1 +Negative regulation of protein import into nucleus 0.6324861232836827 0.6276259784105845 0.5302489863901922 1.0 0.8769195479890357 2 Q9UHD1 1 +Glutamate secretion neurotransmission 0.6324861232836825 0.6276259784105828 0.5302489863901934 1.0 0.8769195479890357 2 Q15042 1 +Glutamate secretion 0.6324861232836825 0.6276259784105828 0.5302489863901934 1.0 0.8769195479890357 2 Q15042 1 +Gamma aminobutyric acid transport 0.6324861232836749 0.6276259784105553 0.5302489863902113 1.0 0.8769195479890357 2 O14745 1 +Negative regulation of neurotransmitter secretion 0.6324861232836735 0.6276259784105499 0.5302489863902149 1.0 0.8769195479890357 2 Q06787 1 +Negative regulation of neurotransmitter transport 0.6324861232836735 0.6276259784105499 0.5302489863902149 1.0 0.8769195479890357 2 Q06787 1 +Negative regulation of cell substrate adhesion 0.3750199693782039 0.6252247412781105 0.5318235658265147 1.0 0.877996286891371 11 P42771,O75122,Q9H6U6 3 +Folic acid containing compound catabolic process 0.6313175576979352 0.6233915047543082 0.5330272791831381 1.0 0.8794916377161608 2 Q9NRN7 1 +Secretory granule organization 0.6302491998822484 0.6225660897446933 0.5335697008276385 1.0 0.8797627483381174 3 P43034 1 +Insulin receptor signaling pathway 0.2810044711401637 0.6221070034544276 0.5338715101520859 1.0 0.8798293636061048 31 P49841,Q06124,Q9H1E3,Q9UQB8,Q9Y5X3,P43490,Q92572 7 +Macrophage chemotaxis 0.4553883194806443 0.6199930850751406 0.5352623395124323 1.0 0.8805713356790501 6 P14174,P30046 2 +Macrophage migration 0.4553883194806443 0.6199930850751406 0.5352623395124323 1.0 0.8805713356790501 6 P14174,P30046 2 +Glial cell development 0.3160590050941314 0.619281049987039 0.5357312260325744 1.0 0.8811228148719387 23 P49770,Q00534,Q14232,Q9NR50,Q9UPY3,Q13144,Q96P11,Q00535 8 +Cardiac muscle contraction 0.3297289671005123 0.6178485957856761 0.5366751464428738 1.0 0.8822350537035971 18 P28161,Q96PU5 2 +Positive regulation of rna binding 0.4547996153320863 0.61751028559788 0.5368981991032333 1.0 0.8823816824952665 6 O15371,P60228,Q04637 3 +Positive regulation of cilium assembly 0.4265677085388108 0.6138734852435469 0.5392989326324407 1.0 0.8842051118876031 7 P49841,P27695,Q15555,P42858 4 +Development of primary sexual characteristics 0.2734508436474424 0.6138015709943192 0.5393464590073429 1.0 0.8842051118876031 34 P49770,P46109,O75874,P16989,P49321 5 +Polysaccharide catabolic process 0.4263096812331722 0.6127197616741245 0.5400616534899445 1.0 0.8842051118876031 7 P08237,P06737,P35573 3 +Cellular polysaccharide catabolic process 0.4263096812331722 0.6127197616741245 0.5400616534899445 1.0 0.8842051118876031 7 P08237,P06737,P35573 3 +Focal adhesion assembly 0.315022461382082 0.6125804010422473 0.540153820626726 1.0 0.8842051118876031 23 O75116,P11274,P18206,Q96AC1,Q9H6U6,P51452,Q9P258,Q9H2G2,P12814,Q14247,O75122,Q7Z460 12 +Macromolecule catabolic process 0.2881065981134396 0.611416724650534 0.5409237332770296 1.0 0.8843673734529215 460 Q9H2J4,O75351,P49721,Q969T7,P28070,Q13200,Q96E52,P67809,Q15370,Q15477,Q16539,Q96F86,Q96K76,P20618,Q5TAX3,Q9BQG2,Q05639,Q96PU5,P39748,Q4G0X4,P16989,Q16850,Q96RU2,O75832,Q9UKS6,P46934,Q13546,Q9HD42,Q00535,Q96Q15,P54727,P28072,P10398,Q13309,P49720,Q04323,Q9UBU6,Q8IYU2,Q93034,Q9UJY5,Q99497,O95155,P15586,Q99570,Q96C86,Q9HCE5,Q9BQ61,Q92995,Q8WW12,Q86W50,O60493,P15311,Q9H1I8,P28074,P24941,Q13526,Q96HR8,Q9H814,P48729,Q9NZZ3,Q8N511,Q8N3C0,Q14011,P60900,Q96KB5,P25788,P08238,Q99436,O95817,Q13107,P68036,Q9GZP4,P61289,Q7Z6Z7,Q8NBM8,P28066,Q8TDB6,P05455,Q92879,Q13614,P49427,P62081,Q9Y5A9,Q9UNS2,Q9HCE1,Q96RL7,O60502,A2RRP1,O95260,O14965,Q9UN37,P51665,P51114,O43847,P42345,Q6NTF9,Q9UPY3,Q96J02,Q15008,Q99575,Q99460,P48556,Q9GZU8,Q9H9H4,P62333,Q16763,P27695,P63208,O14773,Q9NXV2,Q13596,P78559,P17612,P25789,Q92783,Q15386,O95831,Q9Y2L1,P54725,O94966,P25786,O43242,Q9UNM6,Q5T4S7,Q9UHG3,Q86Y37,P06737,P25787,P49841,P40818,Q9NZJ0,Q9UL46,Q9Y5X3,O94888,Q7Z739,Q5VWZ2,Q9NPI6,Q9UNN5 138 +Neurotransmitter gated ion channel clustering 0.6278118609407008 0.6107460619096405 0.5413677067388636 1.0 0.8846544181513606 2 Q9NQX3 1 +Receptor diffusion trapping 0.6278118609407008 0.6107460619096405 0.5413677067388636 1.0 0.8846544181513606 2 Q9NQX3 1 +Chondrocyte differentiation 0.3721363075367592 0.6105217577962292 0.5415162348944753 1.0 0.8846778241448281 11 Q16539,Q9C0E8,O95747 3 +Negative regulation of cellular macromolecule biosynthetic process 0.2422746848681393 0.6097035655189174 0.5420581922219301 1.0 0.8849339785426559 116 P00374,Q96C86,P51114,Q5TAX3,Q9HCE1,Q99543,P49841,Q7Z739,Q969T7,Q14011,Q13535,Q9Y6M1,Q9Y2L1,Q9UNS1,P23396,P67809 16 +Smooth muscle cell migration 0.3569059958542421 0.6094993596493898 0.5421934970642448 1.0 0.8849339785426559 13 Q9UIW2 1 +Reactive oxygen species metabolic process 0.2615474509782451 0.6094744502681018 0.5422100029329167 1.0 0.8849339785426559 45 P00374 1 +Cell projection organization 0.2816725348390189 0.6086798222330495 0.5427366840511083 1.0 0.8853551648762449 277 Q15691,P00374,Q06124,Q14203,Q9BVA1,O60271,Q96G23,O95487,Q14012,Q9UQB8,Q96PU5,Q9BPX3,Q9UBB6,Q9NT62,P46934,Q00535,A6NIH7,Q8TC07,P43034,Q9UIW2,Q86X55,Q9P265,Q15051,Q66K14,Q8N0X7,O60493,P15311,P46108,P16949,P55145,Q6SZW1,Q9H6U6,P07737,Q9P258,Q9Y2J2,Q16555,Q13740,P42858,P08238,P53990,P83731,Q13177,Q8N8S7,Q8IVD9,Q13614,Q15555,Q9HCE1,Q04917,O14965,P42345,P51114,Q12955,Q9UPY3,Q4KMP7,Q16512,P09429,Q9Y496,P27695,Q13596,P78559,A0AVF1,O95721,O43815,P48681,P46109,P36405,Q93008,Q02790,Q01968,Q99873,P46821,Q9NUL3,Q9NQT8,P62330,P07196,O60749,P11233,P07900,Q9NVG8,P35080,O43251,O60678,O95429,Q02750,Q9Y296,Q9UNF0,Q9Y4F1,Q15019,P49841,Q86Y56,Q96HC4,Q6IBS0 92 +Regulation of microtubule based process 0.2502628135021442 0.6082619461107537 0.5430137554594436 1.0 0.8853775341564313 76 Q15691,O75351,Q14203,P16949,Q16512,Q9NZZ3,P78559,P23396,Q8TD16,P78318,P49841,O43379,Q9UHD1,Q9HD42,P46821,Q15555,P43034,O75122,Q6UVJ0 19 +Natural killer cell differentiation 0.6259497369959194 0.6079107568067903 0.5432466648612062 1.0 0.8853775341564313 3 O95251,Q5HYI8 2 +Cell differentiation involved in embryonic placenta development 0.6259497369959127 0.6079107568067685 0.5432466648612206 1.0 0.8853775341564313 3 O75190,Q13043 2 +Regulation of carbohydrate biosynthetic process 0.3302791709285092 0.607848980115221 0.5432876404221427 1.0 0.8853775341564313 17 Q9BYT8,Q13043,A6NDG6,P49841 4 +Cellular response to leucine starvation 0.6256575102279385 0.6069187254349175 0.543904850501256 1.0 0.8854786841318009 3 P42345,Q92616 2 +Establishment of mitotic spindle localization 0.3299839725474803 0.6061006646813599 0.5444479096422765 1.0 0.8854786841318009 17 P43034,Q14674,Q14203,O75122,P42858 5 +Leukocyte chemotaxis 0.2888362259842699 0.6057181460166168 0.5447019321785431 1.0 0.8854786841318009 29 P09429,Q9H4A3,P39019,P04083,O95747,P14174,P30046 7 +Regulation of cellular response to growth factor stimulus 0.2689106017732504 0.6024700779779351 0.5468612749222381 1.0 0.8869033109171083 38 P46934,P62942,Q8N0X7,P98170 4 +Regulation of endodeoxyribonuclease activity 0.4872510209681187 0.6023897385503506 0.5469147389074704 1.0 0.8869033109171083 5 P09429 1 +Mitochondrial rna modification 0.5135989012518667 0.6007461879540439 0.5480090504832991 1.0 0.8874392965226693 4 Q96SZ6 1 +Supramolecular fiber organization 0.2508120239920316 0.6006454951283293 0.5480761291092564 1.0 0.8874392965226693 196 Q9NQP4,Q16658,Q15691,Q99497,P62942,O75190,P47755,P42345,O15144,P15311,Q14203,Q13526,P35080,Q9Y5K6,P16949,Q16512,O95429,P57737,Q96AY3,Q96JJ3,Q15942,Q9UHV9,Q99471,Q9Y281,Q16527,Q86VS8,Q96AC1,P07737,Q9H2G2,P06753,Q9UQB8,P78559,P23396,Q14204,O60504,P08238,O15212,O15145,P07197,O43670,P67936,P08670,P36405,O75116,Q13177,Q9BPX3,P23528,Q93008,P23258,P60983,P35241,Q14195,Q14019,Q9NUQ9,Q9UHD1,Q02790,Q8N8S7,Q13045,Q13546,P46821,P49006,Q9BSJ2,Q92791,Q8IWC1,P60981,P61758,P43034,P62330,P07196,Q6IBS0,O75122,Q9UHB6,O60879,Q7Z460,P04350 75 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4866335342244275 0.5999697163566609 0.5485264181935567 1.0 0.8874392965226693 5 P30154 1 +Regulation of protein neddylation 0.6230869496790181 0.5982150891509441 0.5496964244867077 1.0 0.8883547021859224 3 Q96GG9 1 +Positive regulation of i kappab kinase nf kappab signaling 0.2683211214918125 0.5975695648583959 0.5501271770654936 1.0 0.8886151313932208 38 P19474,Q13325,P62942,O95999,P29692,Q9NYB0,P51617,Q13546 8 +Nucleoside monophosphate catabolic process 0.5122009364200365 0.595497983126842 0.5515106468739541 1.0 0.8901954417710836 4 O43598 1 +Regulation of ubiquitin specific protease activity 0.6218712141889167 0.5941131121009796 0.552436461538323 1.0 0.8906454247689413 3 Q04323 1 +Membrane to membrane docking 0.6218585622443019 0.5940704725549856 0.5524649790473606 1.0 0.8906454247689413 3 P15311,P26038 2 +Golgi to plasma membrane protein transport 0.3257193398891869 0.5938133665758886 0.5526369479245015 1.0 0.8906784525399979 18 Q9UJY5,Q4J6C6 2 +Actin filament polymerization 0.2578169547078563 0.5936358521784002 0.552755696198594 1.0 0.8906784525399979 48 O15144,P47755,P42345,O60610,P35080,O95429,Q12792,P57737,P07737,Q9UQB8,O15145,Q9BPX3,P35241,Q14019,Q9NUQ9,Q13045,P58546,Q9UEY8,P62330,Q14247,Q6IBS0 21 +Striated muscle cell proliferation 0.4217499431630154 0.5924264958505551 0.5535650281514088 1.0 0.8912947082521707 7 Q16539 1 +Postsynaptic cytoskeleton organization 0.4486779057219964 0.5918524516046069 0.5539493961937414 1.0 0.8912947082521707 6 P07196 1 +Smooth muscle cell apoptotic process 0.3754329986133689 0.5907389707688023 0.5546953320258021 1.0 0.8917724990049116 10 P42771,Q53EL6 2 +Response to bmp 0.3293539324121958 0.5906014808190622 0.5547874724543602 1.0 0.8917724990049116 16 Q53EL6,Q8N0X7 2 +Regulation of cell substrate junction organization 0.3145864508784852 0.5900405256969244 0.5551634803346932 1.0 0.8918758456385631 22 Q15555,O75116,Q96AC1,Q9H6U6,P62330,P51452,Q9P258,Q9H2G2,O75122,Q7Z460 10 +Regulation of response to stress 0.2778949656582087 0.5889617346431545 0.5558869431310214 1.0 0.8919138946927605 268 P00374,P25685,P28070,Q06124,P67809,Q16539,P19474,Q96K76,Q96T76,O43813,P04083,Q9Y3Z3,P31689,Q53EL6,Q96G23,O96028,O95881,P14174,P16989,Q99615,P04792,O75832,Q9UHD1,Q13546,Q96Q15,P43034,Q7Z460,Q04323,Q99497,Q99504,P98170,Q92995,P36507,O95251,P15311,P15927,P46108,P55145,Q9NYB0,Q9NY27,Q13535,P60900,Q9NWV8,Q96KB5,P78318,P08238,Q96FW1,P39019,Q13177,Q04637,Q8TDB6,Q92879,Q9Y5A9,Q9BXW9,Q9UNS2,P51452,O75122,Q92905,P51114,Q96J02,Q16512,P09429,Q16543,Q9NUD5,Q96AC1,Q9UNH7,P23396,Q7Z4V5,O94966,P25786,Q99543,P30046,Q00534,Q02750,Q9UNS1,P49841,Q7Z739,Q9NQ88 78 +Regulation of connective tissue replacement 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.8919138946927605 2 O75116 1 +Positive regulation of connective tissue replacement 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.8919138946927605 2 O75116 1 +Connective tissue replacement 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.8919138946927605 2 O75116 1 +Positive regulation of tissue remodeling 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.8919138946927605 2 O75116 1 +Negative regulation of cell substrate junction organization 0.5102126141836687 0.5880575523730236 0.5564936633685709 1.0 0.8921681479169733 4 Q9H6U6,O75122 2 +Phosphatidylinositol metabolic process 0.2909032078841463 0.5871171677801081 0.5571250182422787 1.0 0.8921681479169733 28 Q13614,P42356,P78356,Q96Q15,Q8NEB9,Q9H490,Q01968,Q8NCE2 8 +Developmental process involved in reproduction 0.2293465190050725 0.5870605362244132 0.557163050638861 1.0 0.8921681479169733 157 O75874,P30153,Q9HCE5,P42345,Q8N2A8,Q06124,Q13043,Q14320,P62826,P49321,Q4G0J3,Q16539,Q02750,Q92674,Q15645,Q5TAX3,P04083,Q9BPZ3,Q9H1B7,A0AVF1,Q15019,P08238,P16989,P46109,P41208,O00203,Q9BQA1,Q9GZP4,Q99598,Q92879,P49770,Q9Y5A9,O95747,Q96SB4,Q15392,P54727,P43034,Q13144,Q15102,O14965,O60879,O75190 42 +Aorta development 0.3939934091728174 0.5866532876685491 0.5574365862521982 1.0 0.8921681479169733 8 Q96AY3,Q15036 2 +Regulation of cell morphogenesis involved in differentiation 0.2812799774785917 0.585745712904541 0.5580464097973561 1.0 0.8921681479169733 30 O15144,P46109,Q9NUL3,Q96AC1,P43034,Q9P258,Q9UQB8,P46108,P78527 9 +T cell chemotaxis 0.4827940529086332 0.584985848891825 0.5585572319896936 1.0 0.8921681479169733 5 O95747 1 +Lymphocyte chemotaxis 0.4827940529086332 0.584985848891825 0.5585572319896936 1.0 0.8921681479169733 5 O95747 1 +Interleukin 12 production 0.447002658249331 0.5848834866725721 0.5586260628404232 1.0 0.8921681479169733 6 Q16539 1 +Regulation of spindle assembly 0.3363829746640331 0.5839757763894834 0.5592366096005876 1.0 0.8921681479169733 15 Q9HD42 1 +Response to fibroblast growth factor 0.3666994193524864 0.5830564023849437 0.5598553316371573 1.0 0.8921681479169733 11 Q06124,Q93063,Q8NEM2,P46109 4 +Negative regulation of cell projection organization 0.2759089857144159 0.5830039199563302 0.5598906613729602 1.0 0.8921681479169733 31 Q86X55,Q96G23,Q9P265 3 +Leukotriene metabolic process 0.5088484704079737 0.5829694419569514 0.5599138716076935 1.0 0.8921681479169733 4 Q14914 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.3258658251748622 0.5818513611954763 0.5606668048464845 1.0 0.892443208343445 17 P62942,Q13526 2 +Potassium ion transport 0.3065693127135473 0.5816087562405634 0.5608302435692263 1.0 0.892443208343445 24 Q9H4A3,O75351,Q12955,Q9UHD1,O95747,P46934,Q96PU5 7 +Histone h2b ubiquitination 0.3927421714954568 0.5807684926216719 0.5613964927295396 1.0 0.892443208343445 8 Q6PD62,Q6P1J9,Q5VTR2,O75150,Q9NW82,Q8TDB6,Q8N7H5 7 +Response to bacterium 0.2496688548585422 0.5804167742627385 0.5616335959272176 1.0 0.892443208343445 60 P09429,Q16539,Q9UQB8,P06737,O95999,Q9NZZ3,O60493,P14174,Q53EL6,Q9NUQ9,P81605,O43823,P51617 13 +Erythrocyte development 0.372937590322826 0.5783996662323738 0.5629943192445626 1.0 0.8936331693860237 10 P18074,Q6NYC1,P62753,Q15648 4 +Pro b cell differentiation 0.6184633362547547 0.5774663453585388 0.5636244670486505 1.0 0.893819326322148 2 P78527 1 +Lymphoid progenitor cell differentiation 0.6184633362547547 0.5774663453585388 0.5636244670486505 1.0 0.893819326322148 2 P78527 1 +Cardiac chamber morphogenesis 0.3653248591174985 0.5761679475615912 0.5645016678321391 1.0 0.8946705228506115 11 O96028 1 +Apical protein localization 0.5068304775857837 0.5754677473380365 0.5649749973801677 1.0 0.8946705228506115 4 Q9HD26,P35241 2 +Regulation of tau protein kinase activity 0.6163062536528352 0.5754572691310532 0.5649820820103395 1.0 0.8946705228506115 3 P08238,P07900 2 +Positive regulation of intrinsic apoptotic signaling pathway 0.3267320094991798 0.5754232780136012 0.5650050647189162 1.0 0.8946705228506115 16 P62081,Q99497,O75569,Q9Y3D6,O14745,P63241,P23396,Q07820,O00429 9 +B cell apoptotic process 0.3914653314777639 0.5747797940959775 0.5654402338584843 1.0 0.8947221076489277 8 P46109,Q16512,O95999 3 +Cell maturation 0.2845751923910953 0.5747730032967998 0.5654448271337125 1.0 0.8947221076489277 29 Q8N2A8 1 +Response to peptide hormone 0.2494815560902987 0.5736283032056178 0.5662193547903507 1.0 0.8953029471762992 95 Q96A49,Q5VZ89,Q14232,P42345,P61981,P42224,Q06124,Q9Y266,Q9H1E3,P46108,Q16539,Q13243,Q9NR50,P04083,P27695,P07741,Q9UQB8,P14618,Q92572,P78356,P31751,P49841,O75150,O75116,O43865,O60343,P78527,Q9Y5X3,P43490,P17174,P41240,P46821,O60763,P49770,Q9BSK2,Q13144,P07196,P09960 38 +Recombinational repair 0.2487476208289468 0.5712209297356184 0.5678498924629989 1.0 0.8965907763152308 60 Q9Y248,Q96T76,Q9BRT9,Q7Z4V5,Q9NYB0,Q9Y3Z3,P35244,O60921,Q9H1E3,Q9UNS1,P33991,Q9Y620 12 +Negative regulation of execution phase of apoptosis 0.6164183464797074 0.5702753984377907 0.5684909241428637 1.0 0.8969815334402612 2 Q13177 1 +Histone serine phosphorylation 0.4432765421347572 0.5694673929696286 0.5690389929015824 1.0 0.8969815334402612 6 O14965,Q13043,Q99986 3 +Enucleate erythrocyte differentiation 0.6161262050832677 0.5692508068999245 0.5691859457494814 1.0 0.8969815334402612 2 Q15648 1 +Negative regulation of hepatocyte apoptotic process 0.6161262050832657 0.5692508068999176 0.5691859457494861 1.0 0.8969815334402612 2 Q13131 1 +Regulation of hepatocyte apoptotic process 0.6161262050832657 0.5692508068999176 0.5691859457494861 1.0 0.8969815334402612 2 Q13131 1 +Cell communication by electrical coupling 0.4163778159626326 0.5687576899619752 0.5695205913509238 1.0 0.8972770686700281 7 Q12955,P0DP25,P17612 3 +Dna damage response signal transduction by p53 class mediator 0.3214050089123051 0.5682429517232366 0.569870010020542 1.0 0.8972770686700281 18 Q13535,O75832 2 +V d j recombination 0.442609498175883 0.5667201922848144 0.5709042998370384 1.0 0.8977579066139687 6 P09429,P78527,Q9Y4B6,P18858 4 +Protein localization to nucleoplasm 0.3556987987108012 0.5641086214431593 0.572680211002043 1.0 0.8998104911258228 12 Q9NZM5,P17987,P50991,P78371,P40227,Q99832,Q7L2J0,P50990,P48643,Q4G0J3,P49368 11 +Regulation of epithelial to mesenchymal transition 0.3891573247110862 0.5639978642132482 0.5727555856741433 1.0 0.8998104911258228 8 Q96AC1,O75122,Q7Z460 3 +Endocrine system development 0.332621165280218 0.5630068298752725 0.5734302331897774 1.0 0.9006557296132982 15 P04083,Q00534,Q02750,P46109 4 +Developmental growth 0.2379260093567491 0.5624549828922839 0.5738060667571023 1.0 0.9010313463703712 117 Q92541,Q06124,P61201,P15311,Q13043,Q16539,P04083,Q15056,O60271,Q16555,Q13740,Q96PU5,P53990,P16989,P49841,Q00535,P46821,P52294,Q9BRT9,Q7Z4V5,Q96HC4,P43034,Q9UIW2,Q9P265,Q6IBS0,Q8N0X7 26 +Regulation of membrane protein ectodomain proteolysis 0.5030126250462017 0.5613593886682103 0.5745525632626567 1.0 0.9015674632273732 4 O43847 1 +Positive regulation of neurotransmitter transport 0.5030105438995045 0.5613517286382442 0.5745577841350418 1.0 0.9015674632273732 4 Q15042 1 +Regulation of high voltage gated calcium channel activity 0.6114311003723284 0.5592817293420458 0.5759694625670364 1.0 0.9027082019120076 3 P0DP25 1 +Regulation of protein containing complex assembly 0.2391746294153844 0.5583739763079872 0.576589039384106 1.0 0.903249749909702 115 O15144,Q15691,Q99497,P17931,P47755,P42345,Q06124,P07900,Q14203,P35080,P16949,Q16512,O95429,P09429,P62333,Q96AC1,Q13535,P07737,Q9UQB8,P23396,P19525,P49841,P36405,Q9BPX3,Q04637,Q9NUQ9,Q02790,P46821,Q9NR31,Q86VP6,P62330,Q6IBS0,Q7Z460,P04350,Q9UNN5 35 +Mitochondrial trna processing 0.440451340347299 0.5578586572385614 0.576940904528374 1.0 0.9033443780089864 6 Q96SZ6,Q9Y606 2 +Inner ear receptor cell development 0.3878327065113068 0.5578355153877029 0.5769567083955063 1.0 0.9033443780089864 8 P43034,O95487,O14745,Q9Y6M7,P54802 5 +Pyrimidine nucleobase metabolic process 0.3393689713686644 0.5571837495921442 0.5774018913930756 1.0 0.903664118723446 14 P11172,P42345,Q14195,Q16555,Q9NRF8,P17812 6 +Lymphocyte activation 0.2449842205568967 0.5561385428857831 0.5781161483277144 1.0 0.9037091889438684 105 Q96FZ2,P62942,P17931,Q9UQ84,O95251,Q06124,Q96J02,Q6NYC1,Q16512,P55327,P09429,P24390,Q00534,P04083,O96028,P14174,P23396,Q5HYI8,P78318,P17812,O00203,Q9NUQ9,O14617,Q96L92,P00491,O15347,Q9BXW9,O95999,Q9Y4B6,P51452,P13051 31 +Neuromuscular junction development 0.361065292005984 0.5549707783447235 0.5789146480893295 1.0 0.9047428544819488 11 Q12955,P46934,P46109 3 +Positive regulation of exocytosis 0.3211146237383345 0.5542161899067539 0.5794308996410154 1.0 0.904799838762488 17 Q9UN37,O75351,Q92783,O75122,Q00535 5 +Regulation of ubiquitin protein ligase activity 0.3386742417887249 0.5534682962016159 0.5799427840718572 1.0 0.904799838762488 14 Q16763,P62081,P62841 3 +Maintenance of location in cell 0.2551446770439284 0.5526610991953043 0.5804954955405299 1.0 0.9050677167935604 45 P24390,Q99497,P62942,Q96RL7,P27695,P63208,Q00535,P28161,Q12955,P43034,Q6IBS0,P17612,P0DP25,O14617,P42858 15 +Regulation of oxidative stress induced cell death 0.3162217123400938 0.5511598937878737 0.5815240705663984 1.0 0.9060577734754652 19 O43813 1 +Pyrimidine nucleoside monophosphate metabolic process 0.3741151194752181 0.5499349903820098 0.5823639636718363 1.0 0.906694201352089 9 P33316,P11172,P04818,P34896 4 +Pyrimidine nucleoside monophosphate biosynthetic process 0.3741151194752181 0.5499349903820098 0.5823639636718363 1.0 0.906694201352089 9 P33316,P11172,P04818,P34896 4 +Negative regulation of immune effector process 0.359695301574358 0.5482026465858862 0.5835527650607868 1.0 0.907687547730228 11 P04083 1 +Regulation of transmembrane transport 0.2454113938062495 0.5469051644018251 0.5844438875059925 1.0 0.908644836424411 78 Q9P2B4,Q16539,P62942,P0DP25,P28161,O43865,P46934,Q96PU5 8 +Male gamete generation 0.2463193816474342 0.5466099262426851 0.5846467481149649 1.0 0.9086639726611068 81 Q99598,P16989,Q9HCE5,P41208,P62826,Q15645,Q8N2A8,P54727,P46109,Q96SB4,P43034,O00203,Q14320,Q15102,Q9GZP4,A0AVF1,Q15019,Q4G0J3 18 +Cellular response to ether 0.6075394506136746 0.5464860374509957 0.58473188289266 1.0 0.9086639726611068 3 Q6PKG0,P11802 2 +Negative regulation of response to stimulus 0.2730213790957324 0.5458890053923302 0.5851422364176382 1.0 0.9087321518322296 261 Q8IV63,Q99497,P62942,P30153,P98170,P30086,P28070,Q9UMX5,Q13043,Q96J02,Q13526,Q96B36,P46108,P16949,P67809,P80303,P30046,P31946,Q16539,P19474,Q96K76,Q6SZW1,Q00534,P04083,Q9Y3Z3,Q99471,P31689,Q53EL6,Q96G23,O95881,Q9UNH7,P14174,Q96KB5,P23396,P78318,P42858,Q14152,Q4G0X4,P16989,P78356,Q96FW1,P49841,Q6DKJ4,P04792,Q9HCK8,O75832,Q9NUQ9,Q9UHD1,P46934,Q9Y5X3,Q13546,Q13614,Q01804,P49427,Q7Z739,P43034,P25786,P51452,Q13283,O75122,Q7Z460,Q8N0X7,Q04323 63 +Negative regulation of cellular response to growth factor stimulus 0.3447386882284513 0.5457225385504818 0.5852566766636311 1.0 0.9087321518322296 13 P46934 1 +Regulation of mononuclear cell migration 0.3126256474387105 0.544290251307457 0.5862417543604899 1.0 0.9095094480452692 20 P09429,P46108,P46109,O95747 4 +Excretion 0.4370458235558365 0.5439604625308267 0.5864686805528572 1.0 0.9096474216951612 6 Q96PU5 1 +2fe 2s cluster assembly 0.6082383873794988 0.5418473067932356 0.5879236990924857 1.0 0.9112609979820516 2 O76003 1 +Positive regulation of axon extension 0.3436967136303317 0.5403575565440624 0.5889504723745393 1.0 0.9119277529721256 13 P46821,Q6IBS0 2 +Circadian regulation of gene expression 0.3141841267539543 0.5391481052182111 0.5897846648244125 1.0 0.9124291270881312 19 Q9BQG2 1 +Positive regulation of torc1 signaling 0.6049094097019212 0.5378988055631898 0.5906469130918641 1.0 0.9131480067463552 3 Q9Y4R8,Q9P2J5 2 +Intracellular receptor signaling pathway 0.2387992805142038 0.5373359432861533 0.5910355818238797 1.0 0.9135068125165334 67 Q9GZZ9,P98170,P46934,P42785,Q9NUD5,Q86X55,Q96J02,P04150,Q16512,Q96EK7 10 +Muscle organ development 0.2579398398180602 0.5358002157559476 0.5920966330667139 1.0 0.9142892961292522 41 Q9BYT8,Q16539,P85037,P62942,P16989,P51114,P61201,O94966 8 +Negative regulation of gliogenesis 0.4346486937412717 0.5342418137364768 0.5931742432346419 1.0 0.9155243763527884 6 Q96G23 1 +Transcription elongation from rna polymerase ii promoter 0.2740968972047022 0.5331300705653715 0.5939435445767125 1.0 0.9160682840078822 30 P18615,P55199,Q92541,P35269,Q9Y5B9,Q14241,Q8IXH7,Q9GZS3,Q6IA86,Q9NYV4,P13984,O00267,Q15370,Q4G0J3,Q8WX92 15 +Positive regulation of protein localization to cell surface 0.4948475681172543 0.5315722035936805 0.5950223207957039 1.0 0.9164207744073358 4 P78559 1 +Gliogenesis 0.2461833691574893 0.5314781649843225 0.595087468337546 1.0 0.9164207744073358 58 P49770,Q00534,Q02750,P46109,Q14232,Q9NR50,P04083,P43034,Q06124,Q9UPY3,Q96G23,Q13144,Q96P11,O75306,Q00535 15 +Regulation of dna dependent dna replication 0.3020374562417033 0.5304424788325104 0.5958051805125413 1.0 0.9165054995942782 23 Q9Y248,Q9BRT9,P12004,Q04837,O95251,P40938,P40937,Q9BRX5,Q9UNS1,P24941 10 +Positive regulation of dna binding 0.3148835510369403 0.5302105551453047 0.5959659535912127 1.0 0.9165054995942782 18 P15531,O60869,P0DP25 3 +Regulation of torc2 signaling 0.6047326906222741 0.5298339095285681 0.5962270922683972 1.0 0.9165054995942782 2 Q9Y4R8 1 +Positive regulation of protein kinase activity 0.2428765915002764 0.5294171253625933 0.596516120840316 1.0 0.9165054995942782 62 Q96A49,Q99497,P36507,Q13043,P51617,Q16512,Q02750,Q9H4A3,Q96AC1,Q14012,Q9Y4R8,P23396,P14174,Q86Y37,P08238,Q96M27,O75832,Q00535,P0DP25 19 +Lymphocyte migration 0.3487356522516917 0.5292595381585486 0.5966254199329342 1.0 0.9165054995942782 12 O95747,P46108,P46109 3 +Positive regulation of membrane potential 0.4333736501422527 0.5290945830674884 0.5967398389990901 1.0 0.9165054995942782 6 Q12955,P31751 2 +Regulation of cardiac muscle contraction 0.3557615134305369 0.5289080445017884 0.5968692412084267 1.0 0.9165054995942782 11 P28161 1 +Glycolytic process through fructose 6 phosphate 0.3696900477160764 0.5288582408375925 0.5969037922783642 1.0 0.9165054995942782 9 P85037,P08237,Q9BRR6,P51570 4 +Cardiac muscle cell action potential 0.3483593049995568 0.527395742908782 0.5979187991750594 1.0 0.917140008964708 12 P0DP25,Q96PU5 2 +Gamete generation 0.239947375381118 0.5258400157409329 0.5989993689241071 1.0 0.9174399854009236 110 P30153,Q9HCE5,P42345,P20042,Q8N2A8,P33981,Q14320,P62826,Q4G0J3,Q15645,Q5TAX3,Q9BPZ3,P17612,A0AVF1,Q15019,P52701,P16989,P46109,P41208,Q93008,O00203,Q9BQA1,Q9GZP4,Q99598,Q92879,Q9Y5A9,Q9BXW9,Q96SB4,P54727,O95067,P43034,P62753,Q15102,O14965,O60879 35 +Protein folding 0.2399161660063159 0.5254522006722095 0.5992688734883798 1.0 0.9174399854009236 110 Q9NQP4,P62942,O95433,Q9H2J4,Q99543,P25685,Q9Y266,O95429,Q9UHV9,Q15813,Q16543,Q99471,P31689,O15212,Q15814,Q99615,O95817,P04792,O14737,Q99614,Q9UHD1,Q8IVD9,O60884 23 +Xenobiotic metabolic process 0.3333850073478689 0.5254268457431135 0.5992864953180184 1.0 0.9174399854009236 14 Q9HBK9,P28161 2 +Histone h3 acetylation 0.3157751287723986 0.5236290667995771 0.6005365605606059 1.0 0.917935398826896 17 Q14012 1 +Sprouting angiogenesis 0.3329479054428079 0.5231295071838952 0.6008841328402879 1.0 0.917935398826896 14 P04083 1 +Regulation of sodium proton antiporter activity 0.600299011253792 0.5229661717521942 0.6009977943791405 1.0 0.917935398826896 3 Q9UHD1 1 +Neural precursor cell proliferation 0.2726840374952249 0.5229592570365043 0.6010026063921243 1.0 0.917935398826896 30 O75306,O95456,P55209,O43379 4 +Forebrain radial glial cell differentiation 0.5999047286552176 0.5216963871075794 0.6018817405867556 1.0 0.9181017130155812 3 Q9HCE5 1 +Amino acid salvage 0.5997534971658673 0.5212096542148275 0.6022207295369535 1.0 0.9181017130155812 3 Q13126 1 +L methionine salvage from methylthioadenosine 0.5997534971658673 0.5212096542148275 0.6022207295369535 1.0 0.9181017130155812 3 Q13126 1 +Positive regulation of stem cell proliferation 0.4919260263279509 0.5210475079248252 0.6023336766970981 1.0 0.9181017130155812 4 Q96AC1 1 +B cell homeostasis 0.431343428575704 0.5209311566932482 0.6024147300146536 1.0 0.9181017130155812 6 Q16512,O95999 2 +Negative regulation of lipid localization 0.4918503870056155 0.5207759862554999 0.6025228334535531 1.0 0.9181017130155812 4 Q06124,P31751 2 +Cell killing 0.3032961788744868 0.520289839020032 0.602861576862582 1.0 0.9181017130155812 22 P08238,P07437,Q9NUQ9,P81605,P46108 5 +Golgi to plasma membrane transport 0.2812644092904994 0.5200236215181454 0.6030471113506204 1.0 0.9181017130155812 28 P41240,Q9H4A6,Q9UJY5,Q9HD26,P50570,Q8IYI6,P36405,Q8IWJ2,Q96KP1,Q12955,Q4J6C6,O15027,Q8TAG9,Q15334,O75608 15 +Negative regulation of erad pathway 0.5993571011104538 0.5199346783796215 0.6031091040583887 1.0 0.9181017130155812 3 P54578,Q04323 2 +Response to corticosterone 0.599316258374694 0.5198033777558811 0.603200624858993 1.0 0.9181017130155812 3 P0DP25 1 +Regulation of stem cell proliferation 0.4303930821114594 0.5171237274676703 0.6050697911493723 1.0 0.9182060483757452 6 Q96AC1,O95251 2 +Positive regulation of microtubule nucleation 0.4650088759338449 0.5171193041387505 0.6050728787487181 1.0 0.9182060483757452 5 Q16512 1 +Regulation of cell cycle g1 s phase transition 0.2546063000024795 0.5169964439340656 0.605158641209101 1.0 0.9182060483757452 42 P31350,O95905,P04083,Q7Z7L1,P27695,Q96DY7,P42771,Q04637,P15927,P35241,P24941,P61289,Q6UVJ0,P78527,Q9UL46,Q13642,P23921,Q06323 18 +Cellular extravasation 0.4042859050310898 0.5165188105615991 0.6054921045219033 1.0 0.9182060483757452 7 P46108 1 +Cell junction organization 0.2192759887776783 0.5163844827697611 0.6055859013008404 1.0 0.9182060483757452 132 Q12955,Q14203,Q13526,P35080,O60678,Q16539,Q9H6U6,Q96AC1,P07737,Q9P258,Q9Y4F1,Q9Y2J2,Q14012,P07437,Q9UQB8,O43815,P20810,P46109,Q13177,P46934,Q00535,Q13614,P46821,Q15555,Q96HC4,P43034,P51452,P07196,O75122,Q7Z460 30 +Histone h4 r3 methylation 0.6006427110721676 0.5159522071809535 0.605887789601433 1.0 0.9182060483757452 2 Q99873 1 +Fat cell differentiation 0.2888484749178464 0.5159138862582032 0.6059145550340137 1.0 0.9182060483757452 26 Q16539,Q96A49,P31751,Q96AC1,Q86X55,Q13043,Q96EK7 7 +Intermediate filament based process 0.3388619429618342 0.515680288188621 0.6060777241713582 1.0 0.9182060483757452 13 P48729,P07197,P48681,Q16352,P07196,O75190 6 +Neuron development 0.2485074151398117 0.5148032869412886 0.6066904882440736 1.0 0.9182060483757452 203 P00374,O60493,Q12955,Q06124,Q9UPY3,O43251,P46108,P16949,Q16512,P55145,O60678,P09429,Q6SZW1,Q02750,Q9BVA1,Q9H4A3,Q9Y296,O60271,Q96G23,O95487,Q9Y4F1,Q14012,Q9UQB8,Q9Y2J2,Q16555,P78559,Q9Y6M7,Q13740,Q96PU5,P08238,O43815,P53990,P46109,P49841,P83731,Q13177,Q9UBB6,Q8N8S7,P46934,Q00535,Q13614,P46821,Q15555,Q9HCE1,Q04917,Q96HC4,P43034,Q9UIW2,Q86X55,P07196,Q9P265,Q6IBS0,O14965,Q8N0X7 54 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.2804781884886425 0.5146625220738034 0.6067888669676778 1.0 0.9182060483757452 28 P35606,P83436,P24390,P48444,Q9Y282,P53621,Q9UBF2,P61923,Q9H9E3,A2RRP1,P84085,Q8TD16,P42858 13 +Negative regulation of calcineurin mediated signaling 0.4901028926523763 0.5145167692849916 0.6068907391949516 1.0 0.9182060483757452 4 P49841,Q9UHD1 2 +Negative regulation of calcium mediated signaling 0.4901028926523763 0.5145167692849916 0.6068907391949516 1.0 0.9182060483757452 4 P49841,Q9UHD1 2 +Positive regulation of ion transmembrane transport 0.2884964398656336 0.513621283956502 0.6075167959177397 1.0 0.918731525278674 26 Q9H4A3,P27695,Q00535,P28161,Q12955,Q9UHD1,P0DP25,P30626,P42858 9 +Female meiotic nuclear division 0.3593833953834693 0.5126926677276116 0.608166319492426 1.0 0.9192580146502526 10 O95067,Q15645,P33981 3 +Regulation of dna helicase activity 0.5970192869666893 0.512439302344711 0.6083435904416934 1.0 0.9192580146502526 3 Q04837,P49736 2 +Regulation of nadp metabolic process 0.4637309537576962 0.5123479584000069 0.6084075062693417 1.0 0.9192580146502526 5 Q9NQ88,P18669 2 +Positive regulation of translation 0.2410322767367782 0.5111803683328512 0.6092247639615431 1.0 0.920258855186639 62 Q9HCE5,P51114,P42345,P60228,P13639,P46781,P62701,P78344,P63241,P46777,Q96P11,P67809,O75794,Q06787,Q6PKG0,Q14011,Q71RC2,P14618,P16989,P08670,Q04637,P78527,P98179,O15371,Q9Y5A9,Q86U44,Q96SZ6,Q92615,Q7Z739,Q13144 30 +Regulation of protein phosphorylation 0.2463625414173243 0.5105807768265721 0.6096446392592834 1.0 0.9202604675972512 199 Q96A49,Q99497,P30153,Q9H2J4,P51114,P36507,P33981,P42771,Q06124,Q13043,P35080,Q13526,Q96B36,Q93062,P51617,Q16512,O43823,O95429,Q02750,Q9H4A3,Q9NYB0,Q16543,Q9NY27,Q96AC1,P31689,Q53EL6,O60271,Q9UNH7,Q14012,P14174,Q9Y4R8,Q96KB5,P23396,O60921,P42858,Q86Y37,P08238,O95373,P46109,P31751,Q96M27,Q13177,P04792,O75832,Q9UHD1,Q13546,Q00535,Q96SZ6,Q9P287,O95067,P10398,P51452,P0DP25 53 +Response to ischemia 0.3517482044672061 0.5094450647495327 0.61044029541851 1.0 0.920999893576012 11 Q9NQ88,O95831 2 +Synaptic vesicle localization 0.3446793405577553 0.5092831078708111 0.6105537965583374 1.0 0.920999893576012 12 O00203,O14617,Q92572 3 +Cell projection assembly 0.2373434909981749 0.5085735000535035 0.6110512077691563 1.0 0.9211605657359004 112 Q16658,Q15691,O15144,P42345,P51114,Q9NVG8,P10155,P15311,O15357,Q4KMP7,P27816,Q14203,O00560,P35080,Q12792,O95429,Q06787,P50570,P50395,Q9Y496,P27695,Q9H6U6,Q9UHD8,P07737,Q9P258,Q9P289,Q9H223,Q9Y5K8,A0AVF1,Q15019,P42858,O95721,P49841,P36405,P18206,Q9BPX3,P35241,Q14195,Q01968,Q8IVD9,Q9NT62,P11233,A6NIH7,Q15051,Q15555,Q8TC07,Q9NUL3,Q86Y56,P62330,Q14247,Q6IBS0,Q66K14,Q9H4M9,Q9Y5K6 54 +Positive regulation of hexokinase activity 0.5950961779535288 0.5063046507480088 0.6126427986493073 1.0 0.9222533711815172 3 Q9UNI6 1 +Regulation of receptor signaling pathway via stat 0.3765391419833758 0.5061040014529999 0.6127836416527677 1.0 0.9222533711815172 8 Q9H490,Q13043,P30153 3 +Maintenance of synapse structure 0.4617093175592339 0.5048305210767405 0.6136778769226292 1.0 0.9233883964104022 5 P62330,Q14203 2 +Response to radiation 0.2428544555672119 0.5032491210179103 0.6147891331001256 1.0 0.9236208006051824 98 Q16539,O95155,Q15555,P04083,Q14011,Q13535,Q9H1E3,Q96KB5,P46934,O60921,Q9Y620 11 +Kidney mesenchyme development 0.5940224374866859 0.5028918265624475 0.6150403279518397 1.0 0.9236208006051824 3 O95747 1 +Regulation of kidney development 0.5940224374866859 0.5028918265624475 0.6150403279518397 1.0 0.9236208006051824 3 O95747 1 +Metanephric mesenchyme development 0.5940224374866859 0.5028918265624475 0.6150403279518397 1.0 0.9236208006051824 3 O95747 1 +Coronary vasculature morphogenesis 0.5965527315220738 0.5022187149324456 0.615513679772218 1.0 0.9236208006051824 2 O95487 1 +Coronary artery morphogenesis 0.5965527315220738 0.5022187149324456 0.615513679772218 1.0 0.9236208006051824 2 O95487 1 +Hypothalamus cell differentiation 0.5965527315220669 0.5022187149324229 0.615513679772234 1.0 0.9236208006051824 2 P27695 1 +Synaptic vesicle membrane organization 0.4265123809921177 0.5016701821205745 0.6158995424782332 1.0 0.923922157770502 6 O95721 1 +Positive regulation of posttranscriptional gene silencing 0.3211432254828039 0.500443367139385 0.6167629236695538 1.0 0.9240343626075244 15 Q02750,P51114,P36507,Q9HAV4,Q13546 5 +Negative regulation of protein modification process 0.2176404074948034 0.4976947422295937 0.618699214508144 1.0 0.924349534124512 147 Q99497,P62942,P30153,O43768,P42771,Q96B36,O60678,Q16512,P31946,P19474,Q01105,P62841,Q9NYB0,Q9NY27,P31689,Q53EL6,O60271,Q9UNH7,Q96KB5,P23396,O95373,P46109,Q96FW1,P49841,Q6DKJ4,Q13177,Q13107,P04792,Q04637,Q9UHD1,Q8TDB6,Q00535,P62081,Q96SZ6,P51452,P0DP25,Q04323 37 +Regulation of dna catabolic process 0.5923436586791209 0.4975738768250427 0.6187844200316206 1.0 0.924349534124512 3 O00273,O95831 2 +Regulation of apoptotic dna fragmentation 0.5923436586791209 0.4975738768250427 0.6187844200316206 1.0 0.924349534124512 3 O00273,O95831 2 +Regulation of clathrin dependent endocytosis 0.5917592051431831 0.4957276534343047 0.6200865738687349 1.0 0.92531930994516 3 Q9H3U1,P50570 2 +Positive regulation of dna templated transcription initiation 0.3342669112467781 0.4925717708165529 0.6223151983567428 1.0 0.926734553169936 13 O60244,P62333,Q86VP6,O75448 4 +Response to corticosteroid 0.2682418634503945 0.4913925670214339 0.6231488204015769 1.0 0.9272906653175896 30 P04083,P07196,P04150,P0DP25,O95831,P17174 6 +Presynaptic endocytosis 0.3408498268441063 0.4906568091312174 0.6236691992594818 1.0 0.9272906653175896 12 Q99961,P50570,P62330,P0DP25,Q00535 5 +Neurotransmitter secretion 0.2983480901715525 0.4905975977223351 0.6237110858341444 1.0 0.9272906653175896 22 P49841,Q4J6C6,P35080,Q15042,P0DP25,O95721 6 +Microtubule based movement 0.2415166236041574 0.4893321309708858 0.6246065767874782 1.0 0.9277617291985256 83 Q14203,Q9Y496,Q9Y678,P27695,Q9Y6G9,P78559,A0AVF1,Q8TD16,P78318,Q92572,P42858,P36405,O95817,P04792,O00203,Q9NZ32,O14617,O43237,P46821,Q9UBF2,Q9NUL3,Q96RL7,Q86Y56,Q13409,P43034,P07196 26 +Negative regulation of erbb signaling pathway 0.3611442324940908 0.4888550074199728 0.6249443510649841 1.0 0.9279399637223512 9 P51452,Q9UNH7 2 +Regulation of b cell activation 0.3090914729894449 0.4861024592492873 0.6268945233873664 1.0 0.9292756236045692 17 P14174,Q16512,O15347,O96028 4 +Positive regulation of clathrin dependent endocytosis 0.5915863277826547 0.4857476241027224 0.627146113286132 1.0 0.9294395635751308 2 P50570 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3022713772558613 0.4835709782683832 0.6286903754941522 1.0 0.9305337288629582 20 P08238,Q99497,Q9UL15,O15372,P78559,Q96KB5,P54578,Q04323 8 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.587870661382115 0.483513219569773 0.6287313756607427 1.0 0.9305337288629582 3 O95817 1 +Cellular response to testosterone stimulus 0.5873758036236122 0.4819675109602355 0.6298290260582469 1.0 0.9319490324974103 3 O75116,P26038 2 +Regulation of type i interferon mediated signaling pathway 0.3098902005211824 0.4807315293945834 0.630707319401308 1.0 0.9326206032959672 16 P08238,Q16543,Q9Y3Z3,Q7Z739,Q06124 5 +Leukocyte mediated immunity 0.2437523917634364 0.4793036432594375 0.6317226307001431 1.0 0.9331124037988608 52 P09429,Q9NUQ9,Q96FZ2,O95999,Q9UQ84,O96028,Q9UNH7,P07437,P46108,P13051 10 +Zinc ion homeostasis 0.5848555872528673 0.4741264714654202 0.6354097227421047 1.0 0.9359407805312212 3 O00203 1 +Reproductive system development 0.233881496251219 0.4730380486908205 0.6361860339353886 1.0 0.9359407805312212 69 Q16539,O75874,P16989,P04083,Q15392 5 +Nucleoside monophosphate phosphorylation 0.453028184957463 0.4729929065813021 0.6362182399211775 1.0 0.9359407805312212 5 Q9Y3D8 1 +Cellular response to hormone stimulus 0.2109279798005578 0.4702566608751029 0.638171657097627 1.0 0.9379771602201912 139 Q9GZZ9,Q96A49,Q99497,Q5VZ89,P61981,P42224,Q06124,Q9H1E3,P62826,O43251,P46108,O43823,Q16512,Q13243,P04083,P27695,Q15648,Q9H6U6,P07741,Q9UQB8,P14618,P17612,Q92572,P06730,A5YKK6,P78356,P31751,P49841,O75116,P42785,P40818,O43865,P68036,P35241,P04150,Q02790,O60343,P78527,P46934,P43490,Q9Y5X3,O95831,P17174,P46821,O60763,Q9BSK2,Q9UER7,Q04917,Q86X55,Q13309 50 +Negative regulation of molecular function 0.2622954292192461 0.4699708289640711 0.638375858973574 1.0 0.9380681369491304 244 P17931,Q99497,Q14558,P62942,P98170,O43768,P30086,P42771,Q12955,P61201,Q9H1E3,Q96J02,Q13526,Q96B36,P16949,P51617,Q16512,O95429,Q86YR5,Q9GZU8,Q9P2B4,P31946,P19474,Q96K76,Q01105,Q9HD26,P62841,Q9H4A3,P04083,Q9H6U6,Q9NX74,P31689,Q53EL6,Q9P258,O60256,Q9UN86,Q14012,Q9UNH7,P30740,O00221,P78318,O43924,Q96PU5,P30626,Q96C90,P04080,P06744,P20810,O95373,P78356,P48681,P49841,Q13177,Q9C0C9,P04792,O00170,O75832,Q9UHD1,P46934,Q8TDB6,O14981,Q15257,P62081,Q9BTT0,O95747,Q96SZ6,Q15392,P28161,Q9Y314,Q86VP6,P51452,O14965,P0DP25,O75190,Q04323,Q9UNN5 76 +I kappab kinase nf kappab signaling 0.2429433712599695 0.4690048167095332 0.6390661931052153 1.0 0.9380719947161898 51 P04792,P19474,Q13325,P62942 4 +Regulation of deoxyribonuclease activity 0.392742795365278 0.4681428706667431 0.6396824232916654 1.0 0.9380719947161898 7 P09429 1 +Response to light stimulus 0.236555139925513 0.4676815782334943 0.6400123168008238 1.0 0.9380719947161898 62 Q96K76,O95155,Q15555,Q9UNS2,Q96RU2,Q15004,Q14011,Q13535,Q9NZJ0,Q96KB5,P46934,O60921,P39748 13 +Pyrimidine nucleoside diphosphate biosynthetic process 0.4172299725886202 0.4653475052439971 0.6416826203344723 1.0 0.9380719947161898 6 P23919 1 +Pyrimidine nucleoside diphosphate metabolic process 0.4172299725886202 0.4653475052439971 0.6416826203344723 1.0 0.9380719947161898 6 P23919 1 +Maintenance of postsynaptic specialization structure 0.5816837457074384 0.4643326106170951 0.6424094633678936 1.0 0.9380719947161898 3 P62330 1 +Cell activation 0.2098906743280258 0.4640668991602699 0.6425998161141382 1.0 0.9380719947161898 138 P62942,Q9UQ84,Q96J02,Q6NYC1,Q16512,P09429,Q16539,P24390,P04083,O96028,Q9UNH7,P23396,P78318,P04792,O00203,O14617,O15347,P51452,P13051 19 +Toll like receptor signaling pathway 0.3050620743419839 0.4639188221158774 0.6427059070559393 1.0 0.9380719947161898 17 P09429,Q6SZW1,Q01804,O00203 4 +Negative regulation of vascular permeability 0.5814226976567056 0.463530306711633 0.6429842965598236 1.0 0.9380719947161898 3 Q96AC1 1 +Protein localization to cytoskeleton 0.2985249531183566 0.4621883279187108 0.6439462727782561 1.0 0.9389280756811024 20 Q15555,P49841,Q86VS8,P33981,P78559,Q8IVD9 6 +Positive regulation of growth 0.2387438735704535 0.4614601222769685 0.6444685253400664 1.0 0.9391186773979892 58 O43598,Q16539,P46821,Q96K76,P53990,P16989,Q7Z4V5,Q04637,P15311,P43034,O75832,Q6IBS0,Q96PU5 13 +Cellular response to leucine 0.5804577743625525 0.4605697092762545 0.645107347845101 1.0 0.9397798129723348 3 P42345 1 +Positive regulation of membrane protein ectodomain proteolysis 0.5803959692503023 0.4603803461502383 0.6452432393071583 1.0 0.9397798129723348 3 O43847 1 +Cell substrate adhesion 0.2396827003222945 0.4594192633497376 0.6459331176503518 1.0 0.9401662195598984 56 Q13630,Q00534,P46109,P49841,P42771,Q96AC1,Q9H6U6,P51452,Q13043,O75122,P46108,Q7Z460,O60504,Q00535 14 +Amyloid precursor protein metabolic process 0.2902693519868289 0.4593059214798477 0.6460144960844014 1.0 0.9401662195598984 23 Q15392,P62942 2 +Dna replication checkpoint signaling 0.3905701827083489 0.4592160425643338 0.6460790313419811 1.0 0.9401662195598984 7 O60921 1 +Dna methylation or demethylation 0.283558292691598 0.4589864065842537 0.6462439276826741 1.0 0.9401986253110104 25 Q8N2A8 1 +Modulation by host of symbiont process 0.290114318793498 0.4583924032192809 0.6466705485135953 1.0 0.9403095593013024 23 Q9H1E3 1 +Vitamin b6 metabolic process 0.5831142272860166 0.4581899659675634 0.646815968092505 1.0 0.9403095593013024 2 O00764 1 +Negative regulation of protein maturation 0.4153446068343973 0.4580858642838535 0.6468907541613178 1.0 0.9403095593013024 6 P20810,P98170 2 +Mitotic chromosome condensation 0.3267319128646067 0.4554592005489353 0.6487789132848973 1.0 0.9424307175791192 13 P42695,Q9BXS6,Q9BPX3,O43823,Q9HD42 5 +Regulation of voltage gated calcium channel activity 0.4145001731534806 0.4548466275386689 0.6492195825741485 1.0 0.9428630729959874 6 P0DP25,Q00535 2 +Regulation of microtubule depolymerization 0.3332161666729731 0.4542465547718238 0.6496513785763653 1.0 0.943282354091498 12 O75122,P46821,P78559 3 +Negative regulation of cell junction assembly 0.389256892841365 0.4538488107951432 0.6499376491761593 1.0 0.9434110804074892 7 Q9H6U6,O75122,Q9P258 3 +Retinal ganglion cell axon guidance 0.4727075071177251 0.4537257051051261 0.6500262632297962 1.0 0.9434110804074892 4 Q13740 1 +Rna polymerase ii preinitiation complex assembly 0.3532659002377629 0.4528653874794864 0.6506456759786472 1.0 0.9436479539405704 9 P09429,P62333 2 +Meiotic cell cycle process 0.2420688794715173 0.4520695374964616 0.6512188881493339 1.0 0.9437459836169688 46 Q15645,Q92791,P42695,P33981,Q9UNM6,O95067,Q14674,O60921,Q9Y620 9 +Udp n acetylglucosamine biosynthetic process 0.5774400935125683 0.4513619822887675 0.6517286790920485 1.0 0.9437459836169688 3 Q16222,Q06210 2 +Regulation of vascular permeability 0.3527517564402929 0.4505483079113697 0.6523151297953014 1.0 0.9437459836169688 9 Q07157,Q16625,Q02952,Q9UDY2,P11274,Q96AC1,P07947,Q15149 8 +Synaptonemal complex organization 0.3884359096096775 0.4505047514133198 0.6523465289342791 1.0 0.9437459836169688 7 Q92791 1 +Cell matrix adhesion 0.2510987719847025 0.4496408920676013 0.6529693976773867 1.0 0.9439106078203944 36 Q13630,Q00534,P49841,P42771,Q96AC1,Q9H6U6,P51452,O75122,Q7Z460,Q00535 10 +Negative regulation of establishment of protein localization 0.285365554033241 0.4493101044910541 0.6532079696265805 1.0 0.9439106078203944 24 Q99497,Q16850,O95817,Q06124,P31689,Q9UHD1,O95429,Q00535 8 +T cell proliferation 0.2783882534390364 0.4492736653767239 0.6532342525601698 1.0 0.9439106078203944 26 P09429,P17931,P00491,P04083,P62753,Q96J02,P23396,P17812 8 +Establishment of centrosome localization 0.4463280790973206 0.4489374582228113 0.6534767735445752 1.0 0.9440541072114488 5 P43034 1 +Positive regulation of telomerase rna localization to cajal body 0.3253223915591959 0.4486305067744903 0.6536982230725918 1.0 0.944078565976166 13 O60832,P17987,P50991,P78371,P40227,Q99832,Q9Y230,Q9Y265,P50990,P48643,Q96HR8,P49368 12 +Branchiomotor neuron axon guidance 0.5799006719252205 0.4479215945122231 0.6542097829762024 1.0 0.944078565976166 2 O14786 1 +Striated muscle contraction 0.2932118973055865 0.445671170599572 0.655834792341172 1.0 0.9455955711095811 21 P28161,Q96PU5 2 +Protein modification by small protein conjugation or removal 0.2602232194852148 0.4448484313196192 0.6564292918189893 1.0 0.9456739575646704 243 Q15018,P61201,Q15370,P19474,Q96K76,Q9HC52,P31689,Q96PU5,Q4G0X4,Q96RU2,Q9C0C9,O75832,Q9UHD1,Q9UBW8,Q9NT62,P46934,Q00535,Q01804,P52888,Q86VP6,Q13309,Q04323,Q8IYU2,Q93034,Q99497,P62942,O95155,P98170,Q92995,Q8WW12,P15880,Q13526,Q9NWV8,O75448,P08238,Q96FW1,Q13107,P68036,Q7Z6Z7,Q8TDB6,P49427,P62081,Q9UNS2,Q9NXF7,Q9UII4,Q96DY7,Q9Y4B6,Q92905,Q9GZZ9,Q9NVI1,Q5W0B1,Q96J02,Q9BSL1,P62841,Q14527,Q16763,P63208,Q9H1B7,P23396,Q6DKJ4,Q93008,Q7L5N1,Q15386,Q9UER7,Q9UBV2,O94966,P07900,P06493,O75155,Q9UBE0,P61081,Q5T4S7,Q86UK7,O60678,Q8TBC4,Q8N806,P40818,Q9NZJ0,Q96GG9,O95999,Q9Y314,Q9UBT2 82 +Muscle cell proliferation 0.2699475562980547 0.44467196395173 0.6565568329366944 1.0 0.9456739575646704 28 Q16539,Q53EL6 2 +Negative regulation of axon extension 0.4700226650700939 0.4446033200194539 0.6566064477811735 1.0 0.9456739575646704 4 Q9P265 1 +Mammary gland development 0.2953193475533254 0.4441601786488928 0.6569267804068779 1.0 0.9458201205899148 20 P15531,P11172,Q99808,P31751,Q9UNS2,P61201,P07741 7 +Secretory granule localization 0.5747723725656034 0.4432875621038099 0.657557751093788 1.0 0.946010627501146 3 O60763 1 +Positive regulation of jun kinase activity 0.4695542945551028 0.4430194339845628 0.6577516779497226 1.0 0.946083146638571 4 Q16512 1 +Negative regulation of kinase activity 0.2385101649837099 0.4403067633457619 0.659714942902135 1.0 0.9476663551124151 54 O95373,P78356,Q9UHD1,Q96SZ6,P42771,P04792,P31689,Q53EL6,P51452,Q9UNH7,Q96B36,Q16512 12 +Negative regulation of hydrolase activity 0.2317781864743922 0.4395316863606364 0.6602763276665682 1.0 0.9481578731295496 71 Q99497,P62942,P98170,P30086,P61201,O95429,Q86YR5,Q96K76,Q9H4A3,P04083,Q9H6U6,Q9P258,P30740,P78318,P04080,P06744,P20810,P49841,Q13177,Q9C0C9,O00170,Q9UHD1,Q15257,Q15392,O75190,Q04323 26 +Positive regulation of cellular amide metabolic process 0.2291403131701936 0.4390087140713298 0.6606552222272244 1.0 0.9481905562642856 67 Q9HCE5,P51114,P42345,P60228,P13639,P46781,P62701,P78344,P63241,P46777,Q96P11,P67809,O75794,Q06787,Q6PKG0,Q14011,Q71RC2,P14618,P16989,O75116,P08670,Q04637,P78527,P98179,O15371,Q9Y5A9,Q86U44,Q96SZ6,Q92615,Q7Z739,Q13144 31 +Histone mrna metabolic process 0.3434706661686129 0.4387966598929698 0.660808880735563 1.0 0.9482046455831152 10 Q5TAX3 1 +Muscle cell differentiation 0.2290590109022905 0.4382059419461009 0.6612370016201745 1.0 0.948412893588466 67 Q16539,Q7Z4V5,Q8IV08,Q16527,Q53EL6,Q14012,P67809 7 +Regulation of cyclic nucleotide phosphodiesterase activity 0.467497805943932 0.436091777671142 0.6627701425500501 1.0 0.9494440958856218 4 P0DP25 1 +Regulation of insulin receptor signaling pathway 0.301328742124215 0.4347211607657237 0.6637648367971576 1.0 0.9494440958856218 16 Q06124,Q9Y5X3,Q9H1E3 3 +Regulation of entry of bacterium into host cell 0.5718877849210905 0.4346271200354858 0.6638331064831358 1.0 0.9494440958856218 3 Q9UPT5,Q96KP1 2 +Zymogen inhibition 0.4667897510974868 0.4337167348917941 0.6644941526840098 1.0 0.9499773269340692 4 P98170 1 +Establishment of cell polarity 0.2395499772313018 0.4334943552231518 0.6646556660501235 1.0 0.9500022009111913 48 Q96L92,P08238,P46821,P46109,P49841,Q9H6U6,P43034,P15311,P62330,Q14203,Q9NUQ9,P46108,Q7Z460,P07900,P42858 15 +Positive regulation of catecholamine metabolic process 0.571303331385139 0.4328814245817192 0.6651009154365302 1.0 0.9504325242916988 3 Q99497,P00492 2 +Axis elongation 0.5712169951374443 0.4326238075684712 0.6652880906725389 1.0 0.9504616567784552 3 Q15648 1 +Positive regulation of protein modification by small protein conjugation or removal 0.2395178408155096 0.4319361999646399 0.665787783698832 1.0 0.9504616567784552 47 Q9NVI1,P62942,O95999,P98170,Q9UBE0,Q16763,P15880,P68036,O75832,Q13309,Q13526,Q7Z6Z7,Q9UBT2,Q96GG9 14 +Negative regulation of nucleocytoplasmic transport 0.3838193704666468 0.4318642525267269 0.6658400773812074 1.0 0.9504616567784552 7 Q9UHD1,Q00535 2 +Skeletal system development 0.2369413467060022 0.4305019438785864 0.6668305529766974 1.0 0.9512544915001924 55 Q16539,Q15125,Q96AQ6,O96028 4 +Regulation of erad pathway 0.3592742280745873 0.430165297477103 0.6670754035835731 1.0 0.9513978927786484 8 O94966,Q92995 2 +Positive regulation of locomotion 0.2368212767884025 0.4292037141147919 0.6677749803202162 1.0 0.9514415635482798 93 P09429,Q16539,P06744,Q15555,P46109,O95747,P04083,O43379,P04792,Q96AC1,P07737,Q9H9T3,O75122,P46108,Q16512,O95429 16 +Development of secondary sexual characteristics 0.5700443066124826 0.4291312833454021 0.6678276872781994 1.0 0.9514415635482798 3 Q9H1B7 1 +Development of secondary female sexual characteristics 0.5700443066124826 0.4291312833454021 0.6678276872781994 1.0 0.9514415635482798 3 Q9H1B7 1 +Membrane biogenesis 0.2875252269271306 0.427772669931493 0.6688166364595811 1.0 0.9514856384958246 22 Q12955,Q9NZZ3,Q9UN37,Q9HD42 4 +Free ubiquitin chain polymerization 0.5734735612036346 0.4277007550265914 0.6688690001197892 1.0 0.9514856384958246 2 Q16763 1 +Calcium mediated signaling 0.2943580726067359 0.4268363809768943 0.6694985058840401 1.0 0.9521756528128572 19 P42345,P49841,Q9Y3D6,P28161,Q9UHD1,P0DP25,P42858 7 +Positive regulation of calcium ion transport 0.2961467887296021 0.425736401996787 0.6702999337041038 1.0 0.9526988277226072 18 P42858,P17931,P27695,P28161,P0DP25,Q00535 6 +Phosphatidylinositol dephosphorylation 0.406259888704018 0.4236790062507852 0.6717999277937772 1.0 0.9545884891688692 6 Q13614 1 +Negative regulation of cell killing 0.4636894839575123 0.4233796648703173 0.6720182789899269 1.0 0.9545884891688692 4 P46108,P08238 2 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.4636706371577523 0.4233171375563779 0.672063892328993 1.0 0.9545884891688692 4 Q53EL6 1 +Neurotransmitter reuptake 0.4634802665632919 0.4226857657574354 0.6725245422805823 1.0 0.9548313122363984 4 Q99497 1 +Regulation of hydrolase activity 0.2364068468844713 0.4213527606679206 0.6734975087256199 1.0 0.9558009854723974 191 Q8IV63,P17931,Q99497,P62942,P98170,P42345,O43847,Q9NVG8,P30086,Q5H9R7,P61201,Q13526,P46108,P16949,O95429,Q86YR5,P09429,Q96K76,Q8WU90,Q9H4A3,P04083,Q96HP0,Q9H6U6,Q96AC1,Q9P258,P23396,P30740,Q92688,P78318,P42858,P25788,P04080,Q96AQ6,P08238,P20810,P06744,P46109,P31751,P49841,Q13177,Q9C0C9,O14737,O00170,P61289,Q9UHD1,O60343,Q15042,Q01968,Q9UL46,O95831,Q15257,Q15555,O95999,Q8TC07,Q15392,Q9Y3D6,P43034,Q9UIW2,Q66K14,P0DP25,O75190,Q04323 62 +Regulation of dopamine receptor signaling pathway 0.5711364300321439 0.4204546324829003 0.6741533648628764 1.0 0.95599708169889 2 O14744 1 +Positive regulation of dopamine receptor signaling pathway 0.5711364300321439 0.4204546324829003 0.6741533648628764 1.0 0.95599708169889 2 O14744 1 +Organelle membrane fusion 0.2530174242947891 0.4174331336875387 0.6763616236884433 1.0 0.9576837312894968 31 Q15075,Q9UN37,P78356,P04083,O60343,Q8WUH2,O95721 7 +Vocalization behavior 0.5696757230499632 0.4159553300024062 0.6774426906920956 1.0 0.9587166631692344 2 Q15334 1 +Trna metabolic process 0.2355508694965586 0.4154653199851229 0.6778012976400689 1.0 0.9589300701523196 92 P54577,P49589,Q9NXH9,Q13395,Q9UPY3,Q99575,Q9HA77,Q9UI30,Q9Y606,Q9Y3C4,Q9UBP6,Q9NX74,Q9UJA5,Q9H9T3,O95163,P26639,P26640,Q9NXG2,P78346,P05455,Q9Y285,Q9BTE6,P49591,Q9BQ52,Q96SZ6,Q7Z4G4,Q8WWH5,Q96PZ0,Q9NSD9,A2RTX5,Q9NPF4,Q969Y2,O43776 33 +Nucleic acid phosphodiester bond hydrolysis 0.2352875115088301 0.4153517473649767 0.6778844245919007 1.0 0.9589300701523196 96 Q96F86,Q96C86,Q8IV08,Q9UQ84,Q8N2A8,Q9Y3Z3,Q9BQ61,Q2NL82,Q9BQG2,Q9Y2L1,Q9UPY3,Q9HB07,P23396,Q9NPI6,Q15631,Q99598,O95831,P39748 18 +Response to interferon gamma 0.2762456785072444 0.4149372468411502 0.6781878422915921 1.0 0.95898494026996 25 P19474 1 +Regulation of nucleocytoplasmic transport 0.2366182879085462 0.4147890628476442 0.6782963268266693 1.0 0.95898494026996 51 Q16539,Q14012,Q9C0E2,P46934,Q92688 5 +Heart valve morphogenesis 0.4362738305492073 0.4137458269469221 0.6790602616352595 1.0 0.9594088372764462 5 P42345,Q13464,O75116 3 +Meiosis i cell cycle process 0.2760356869071597 0.4136968671075908 0.6790961217736495 1.0 0.9594088372764462 25 Q15645,Q92791,O95067,Q14674,Q9Y620 5 +Vesicle mediated transport to the plasma membrane 0.2361811205906654 0.4111241006503487 0.6809815386996116 1.0 0.9604143197928776 51 Q9UJY5,O75436,O60493,Q9UID3,Q12955,O15027,Q9HD26,P50570,Q96KP1,Q15036,Q9H223,P36405,Q8IWJ2,Q4J6C6,O75608,P41240,Q96L92,Q9UMY4,Q8IYI6,P62330,Q9H4M9 21 +Striated muscle cell apoptotic process 0.4024385870692347 0.4095080975573651 0.6821668255111368 1.0 0.9610487019717556 6 O95817 1 +Asparagine metabolic process 0.5631209818819327 0.4087681325518272 0.6827098283375119 1.0 0.961423454048468 3 P08243,Q7L266 2 +Biological process involved in intraspecies interaction between organisms 0.4018544759077052 0.4073583309182546 0.6837448266402686 1.0 0.9620588894797548 6 Q96RL7 1 +Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.561605328810024 0.4043697385659451 0.6859408496915311 1.0 0.9641657102814472 3 Q99497 1 +Mononuclear cell differentiation 0.235781434491125 0.4038920375090099 0.6862921118675995 1.0 0.9641657102814472 49 P09429,P24390,O00625,P17931,Q00534,O15347,Q9BXW9,P00491,P04083,Q9Y4B6,O95251,O00203,O14617,Q6NYC1,Q5HYI8,P55327 16 +Toxin transport 0.315733665401669 0.4031966155466342 0.686803589277597 1.0 0.9641657102814472 13 Q9UJY5 1 +Microtubule cytoskeleton organization involved in mitosis 0.2326469141105099 0.4031331723362362 0.6868502584050027 1.0 0.9641657102814472 81 Q15018,P42858,O43670,O75351,Q9NZZ3,Q15813,Q9P287,Q9HBM1,O43379,P33981,P43034,Q9Y266,Q14674,Q14203,O75122,P16949,Q7Z460,Q9HD42 18 +Regulation of cytokinesis 0.2594282415490214 0.4030845195632096 0.6868860484249799 1.0 0.9641657102814472 29 P41208,P0DP25,Q9UN37,Q13526 4 +Cytokine mediated signaling pathway 0.235138378777769 0.4024272636268115 0.6873696087013734 1.0 0.9641657102814472 51 P08238,Q8WU90,Q01804,P98170,Q9H4A3,Q16543,Q9Y3Z3,Q7Z739,P43034,Q06124,P63241,O95747,P51617,Q13546 14 +Positive regulation of protein catabolic process 0.2314969311780274 0.4023546098412736 0.6874230698346651 1.0 0.9641657102814472 78 Q9UJY5,P62191,O43847,Q92995,Q9UNN5,P15311,Q96J02,Q15370,P48729,P62333,Q13596,P17980,Q96PU5,P62195,P49841,O75832,Q9NZJ0,Q7Z6Z7,Q9UKS6,P46934,P54725,O14965,P07900,Q8IYU2 24 +Mrna transcription 0.3153181122816678 0.4012695464309088 0.6882216823292759 1.0 0.9641657102814472 13 Q12800 1 +Regulation of cellular component size 0.2340580086078941 0.4011473154084823 0.688311666828517 1.0 0.9641657102814472 95 O15144,P26038,P47755,P42345,P15311,P35080,P78344,Q96B36,Q12792,O95429,P50570,Q9Y281,P07737,Q9UQB8,Q16555,P08238,Q9Y243,O15145,P53990,P49841,Q9BPX3,P35241,O14745,Q14019,Q9NUQ9,Q13045,Q00535,P20337,P58546,P46821,P60981,Q9UEY8,P43034,P62330,Q14247,P07196,Q9P265,Q6IBS0,Q9UHB6,Q9UL25,Q8N0X7 41 +Regulation of myeloid cell differentiation 0.2444595530559316 0.4011192824745336 0.6883323048425571 1.0 0.9641657102814472 36 Q16539,Q00534,O15347,P42345,Q15648,P42224,O95251,Q96KR6,Q9GZS3,Q9GZP4,O43251,P78527,Q99873,Q13546 14 +Keratan sulfate metabolic process 0.5602109445111735 0.4003424894734355 0.6889042767697182 1.0 0.9641657102814472 3 P15586 1 +Snrna modification 0.4321568459556678 0.3996671228462628 0.6894017105305621 1.0 0.9641657102814472 5 Q4G0J3 1 +Centromeric sister chromatid cohesion 0.4320739843137506 0.3993858128353851 0.6896089459104366 1.0 0.9641657102814472 5 P41227,Q9GZZ1,P30153 3 +I kappab phosphorylation 0.4562993276819748 0.3991586377044814 0.6897763182171277 1.0 0.9641657102814472 4 O14920,Q13162,O15111 3 +Regulation of microtubule nucleation 0.3992975701304345 0.397999896327102 0.6906302621675329 1.0 0.9651546932814028 6 Q16512 1 +Peptide catabolic process 0.3272380385339348 0.3961178169170933 0.6920181150860341 1.0 0.966479537001512 11 Q9NQW7,O14773,Q8WUX2,Q6P179 4 +Regulation of protein acetylation 0.2729009415911258 0.3953510745344735 0.6925838109659945 1.0 0.966655194132508 25 Q01105,Q9P265,Q14012 3 +Negative regulation of myosin light chain phosphatase activity 0.5578609000584407 0.3935972045750432 0.6938784454033027 1.0 0.9667021411871152 3 Q13464,O75116 2 +Negative regulation of bicellular tight junction assembly 0.5578609000584407 0.3935972045750432 0.6938784454033027 1.0 0.9667021411871152 3 Q13464,O75116 2 +Negative regulation of nuclear division 0.2813781555953881 0.3935175324661873 0.6939372773206052 1.0 0.9667021411871152 22 O43670,Q15645,Q96DY7,P33981,Q9Y6G9 5 +Positive regulation of neural precursor cell proliferation 0.3504266694208598 0.3929364529030995 0.6943664170565402 1.0 0.9668163752247252 8 O43379 1 +Regulation of synaptic transmission gabaergic 0.557276446522494 0.391927927919981 0.6951114669812037 1.0 0.9670080426949916 3 P21359,P27695 2 +Positive regulation of catalytic activity 0.248328397208735 0.391605890554291 0.6953494348285683 1.0 0.9670080426949916 222 Q9Y248,Q96A49,P00374,Q99497,Q8IV63,Q99570,P42345,P36507,Q9NVG8,P15880,Q4KMP7,Q13043,Q13526,P49643,P51617,Q96HR8,P46108,Q16512,P31946,P09429,Q16539,Q8WU90,Q02750,Q9H4A3,Q16763,Q96HP0,P78371,P63208,Q9H6U6,Q96AC1,Q9P258,Q14012,P14174,Q9Y4R8,P23396,Q92688,Q05639,Q86Y37,Q9UNI6,P08238,P46109,P31751,P49841,Q96M27,Q13177,Q04837,O14737,P68036,O75832,P61289,O60343,Q15042,Q9UL46,Q8TDB6,Q00535,O95831,Q96GG9,Q15257,Q15555,O95999,Q9BRT9,Q8TC07,Q9Y3D6,Q9NPI6,Q66K14,P0DP25,Q9NQ88 67 +Negative regulation of erk1 and erk2 cascade 0.2997559941414177 0.3905928772319324 0.6960981913825701 1.0 0.9670529191942744 15 Q8IV63,P51452,Q14152,Q13526 4 +Regulation of ossification 0.325957423348409 0.3904885304888158 0.6961753348613071 1.0 0.9670529191942744 11 Q16539,Q06124,O95747 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.3319531288078002 0.3878668858279993 0.6981145447457531 1.0 0.9675698491908216 10 Q96K76,P13693,P14174,P23396,Q9HBM6 5 +Epithelial cell maturation 0.5603271983640199 0.3877107479304335 0.6982301010783054 1.0 0.9675698491908216 2 P04818 1 +Negative regulation of signal transduction by p53 class mediator 0.348939896164246 0.3868032904724505 0.6989018410411039 1.0 0.9675978374740072 8 O75832 1 +Peptidyl serine autophosphorylation 0.5553353379382592 0.3864077052844318 0.6991947444503963 1.0 0.9675978374740072 3 Q13546 1 +Cell division 0.2445475943564209 0.3862891794685467 0.6992825133202076 1.0 0.9675978374740072 214 Q15018,Q15691,Q9UN37,Q99570,O43768,O75351,O75400,Q9H6D7,Q12955,Q9Y266,Q14203,P24941,P62826,Q13526,P16949,P67809,O75794,Q96CS2,P48729,Q00534,Q9HC35,Q9NZZ3,Q9HBM1,Q9NWV8,Q14674,Q9UNS1,Q9Y6G9,P07437,P23396,Q96CT7,Q15019,P53990,O43670,P41208,Q8NEB9,P40818,Q9BPX3,P04150,P18858,Q00535,Q9HD42,Q6DKK2,Q15555,P42695,O95067,P43034,Q6P1K2,O75122,P0DP25,Q7Z460,Q8N0X7 51 +Striated muscle cell differentiation 0.2350700480994234 0.3860979820323758 0.6994241043027374 1.0 0.9675978374740072 45 Q9BYT8,Q16539,Q8IV08,Q16527,Q96HC4,P67809 6 +Plasma membrane organization 0.2483108055594197 0.3858445064220064 0.6996118314100088 1.0 0.967654467615354 31 Q9NZZ3,Q12955,Q9UNF0,Q9Y2J2,Q9UQB8,Q9UKS6,Q9HD42 7 +Regulation of microvillus organization 0.4518850409852999 0.3849828565023955 0.7002501170090096 1.0 0.9683102360434632 4 P15311,Q6IBS0 2 +Post translational protein modification 0.2984943816667967 0.3844270168672955 0.7006619794937783 1.0 0.9683102360434632 15 Q9HA64 1 +Regulation of translational fidelity 0.2910124692906005 0.3814995053047242 0.7028326382137566 1.0 0.97048025787706 16 Q99543,P26640,Q96SZ6,Q9BTE6 4 +Positive regulation of rna polymerase ii transcription preinitiation complex assembly 0.5524443839944655 0.378254844875552 0.7052412863198407 1.0 0.971824085573795 3 P62333 1 +Plus end directed organelle transport along microtubule 0.5571136430032269 0.3782273065453618 0.7052617418721243 1.0 0.971824085573795 2 Q9Y496 1 +Positive regulation of synaptic transmission gabaergic 0.5571136430032266 0.3782273065453612 0.7052617418721248 1.0 0.971824085573795 2 P27695 1 +Dense core granule transport 0.5571136430032255 0.3782273065453582 0.705261741872127 1.0 0.971824085573795 2 Q12756 1 +Anterograde neuronal dense core vesicle transport 0.5571136430032255 0.3782273065453582 0.705261741872127 1.0 0.971824085573795 2 Q12756 1 +Cardiac cell development 0.3101494041090569 0.3776072537982013 0.7057223752490529 1.0 0.971824085573795 13 P42345,Q96HC4,Q53EL6 3 +Positive regulation of fibroblast migration 0.4254014251027742 0.3770053766624877 0.7061696092446075 1.0 0.9720338409146904 5 O95429 1 +Positive regulation of leukocyte chemotaxis 0.3099550268093903 0.3767286962479432 0.7063752349115591 1.0 0.9721138932227552 13 P09429,O95747 2 +Enteroendocrine cell differentiation 0.3927446997746019 0.3744128587364393 0.7080971776441207 1.0 0.9736705454797756 6 Q00534 1 +Positive regulation of tyrosine phosphorylation of stat protein 0.44840689856769 0.3739724489058349 0.708424813991368 1.0 0.9738280702202948 4 P22059,Q92769,Q00613 3 +Regulation of transferase activity 0.2334479446995717 0.3732647115198576 0.7089514377214041 1.0 0.9742355383488632 192 Q9Y248,Q96A49,Q99497,Q99570,P42345,P36507,P49736,P61981,P42771,P40938,P15880,Q13043,Q13526,Q96B36,P49643,P51617,Q96HR8,Q99640,Q16512,Q02750,P62841,Q9H4A3,Q16543,Q16763,P78371,P63208,Q96AC1,P31689,Q53EL6,P13010,Q14012,Q9UNH7,P14174,Q9Y4R8,P23396,Q05639,P42858,Q9UNI6,Q86Y37,P08238,O95373,P78356,P49841,Q96M27,Q13177,P04792,Q92616,P68036,O75832,Q9UHD1,Q8TDB6,Q00535,Q96GG9,P62081,O95999,Q9BRT9,Q9UER7,Q96SZ6,Q9UII4,Q9P287,O95067,P51452,P0DP25,Q9NQ88,P07900 65 +Peptidyl threonine dephosphorylation 0.4479648426691803 0.37258330184154 0.7094586026136773 1.0 0.9745154274564396 4 O15355 1 +Regulation of centrosome cycle 0.2859533947117617 0.3723952201204058 0.7095986122255629 1.0 0.9745154274564396 18 O14980,Q9NZZ3,O75351,O43379,Q9UHD1,O14965,Q6UVJ0,Q9HD42 8 +Leukocyte differentiation 0.2242280372629191 0.3721382913339368 0.7097898880182472 1.0 0.974575076404142 70 P17931,O95251,Q6NYC1,P55327,P09429,Q16539,P24390,Q00534,P04083,Q5HYI8,O00203,O14617,Q13546,O00625,O15347,P00491,Q9BXW9,Q9Y4B6,P43034,Q04760 20 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.5547765118317372 0.3714046242866965 0.7103361818209408 1.0 0.9747604416762032 2 P60953 1 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.5547765118317372 0.3714046242866965 0.7103361818209408 1.0 0.9747604416762032 2 P60953 1 +Positive regulation of neuron apoptotic process 0.3215503498267545 0.3713612255670165 0.7103685014885437 1.0 0.9747604416762032 11 O95831,P49427,P61081,Q07820,Q00535 5 +Ribonucleoside diphosphate metabolic process 0.2341426429502731 0.3708196137375349 0.7107718916152912 1.0 0.9749080960316272 44 P08237,P00558,Q13131,P85037,Q9BRR6,P14618,P51570,P06744,P11172,P00338,P31350,P36871,Q9UDY2,Q01813,P23921,P60174,P54619,P18669,Q9UKK9,Q9NQ88 20 +Dna damage induced protein phosphorylation 0.5541922290388646 0.3697088376005995 0.7115994462070734 1.0 0.97539060649253 2 O96017 1 +Response to metal ion 0.2227905305542117 0.3693545070888494 0.7118635024022393 1.0 0.97539060649253 66 Q86YQ8,O60888,O43865,P46934,Q96PU5 5 +Convergent extension 0.5539000876424311 0.3688624345432598 0.7122302648154741 1.0 0.9756903378353294 2 Q13263 1 +Neural nucleus development 0.2862536357309037 0.3653494258549998 0.7148505880101135 1.0 0.97614562123149 17 P12277,Q16352,Q04917,P27348,O95487,P62258,P0DP25 7 +Cell substrate junction organization 0.2493629053172426 0.3651862521828775 0.7149723798620566 1.0 0.97614562123149 30 Q15555,O75116,P11274,P18206,Q96AC1,Q9H6U6,P62330,P51452,Q9P258,Q9H2G2,O75122,Q7Z460 12 +Regulation of metalloendopeptidase activity 0.5524393806602499 0.3646453777808507 0.715376137161607 1.0 0.97614562123149 2 Q13492 1 +Leptin mediated signaling pathway 0.5524393806602488 0.3646453777808477 0.7153761371616092 1.0 0.97614562123149 2 Q96EB6 1 +Response to leptin 0.5524393806602488 0.3646453777808477 0.7153761371616092 1.0 0.97614562123149 2 Q96EB6 1 +Cellular response to leptin stimulus 0.5524393806602488 0.3646453777808477 0.7153761371616092 1.0 0.97614562123149 2 Q96EB6 1 +Positive regulation of immune response 0.2251498116771365 0.3640200008079193 0.7158430740489121 1.0 0.9765806175766616 73 Q96FZ2,Q99497,Q14232,P15311,Q16512,P09429,Q9H4A3,Q9NR50,P04083,Q9NUD5,O96028,P23396,P46109,P39019,Q9NUQ9,P49770,O95999,Q13144,P51452 19 +Positive regulation of protein import 0.2780405126610709 0.3628758784627142 0.7166976065259814 1.0 0.9766881700445008 21 Q16539,O95817 2 +Neurotransmitter transport 0.2489480956703329 0.3625752372633075 0.7169222110655942 1.0 0.9766881700445008 30 Q99497,P49841,Q00535,Q4J6C6,P35080,Q15042,P0DP25,O95721 8 +Regulation of synaptic transmission glutamatergic 0.4446815690584503 0.3623389856325908 0.7170987283032488 1.0 0.9766881700445008 4 Q15042 1 +Fructose 6 phosphate metabolic process 0.3658380413163898 0.3621110143374817 0.7172690731499742 1.0 0.9766881700445008 7 P08237,Q06210,P37837 3 +Centriole assembly 0.3193435640748271 0.3619298375896105 0.717404462176743 1.0 0.9766881700445008 11 P41208,O75351,Q6UVJ0,O43379 4 +Neuronal stem cell population maintenance 0.3886128578638222 0.3598441322083852 0.7189636980745142 1.0 0.9780961620175757 6 Q86VS8 1 +Negative regulation of carbohydrate metabolic process 0.3187117043230203 0.3592477808789965 0.7194097350972755 1.0 0.9780961620175757 11 P49841,Q9NQ88,Q13043 3 +Cellular response to insulin stimulus 0.2276961693224185 0.3591452314128002 0.7194864459244585 1.0 0.9780961620175757 57 Q96A49,O60343,O60763,Q5VZ89,Q13243,P31751,P49841,P78356,Q9BSK2,Q06124,Q9H1E3,P07741,Q9UQB8,Q9Y5X3,P43490,Q92572,P17174 17 +Cardiac ventricle development 0.2932154907082789 0.3590482093932794 0.7195590246162911 1.0 0.9780961620175757 15 O96028 1 +Actin filament based process 0.2314118391177398 0.3589171717861031 0.7196570531621318 1.0 0.9780961620175757 190 Q16658,Q9UN37,O75190,O15144,P47755,Q9H2J4,P42345,O60610,P15311,O15357,Q15417,O00560,P35080,P46108,P60660,P16949,Q16512,O95429,P57737,Q96JJ3,Q16352,Q15942,Q8WX93,P04083,Q9Y281,Q16527,Q9H6U6,Q96AC1,P07737,Q9UNF0,Q9Y4F1,P06753,Q9UQB8,Q9H8V3,Q9Y2J2,P30626,O60504,Q96PU5,O15145,Q86TU7,P67936,O75116,P11274,Q13177,Q9BPX3,P23528,Q01518,P60983,P35241,Q14195,P29966,Q99439,Q27J81,Q8N8S7,Q14019,Q9NUQ9,Q9P1F3,Q13045,Q00535,P46940,P49006,P60981,Q9NUL3,Q9UEY8,P43034,P62330,Q96HC4,Q14247,Q6IBS0,O75122,P11233,O60879,Q7Z460,Q9UHB6,Q9Y5K6 75 +Regulation of cellular response to insulin stimulus 0.2849451874826536 0.3588279620831309 0.7197237931104403 1.0 0.9780961620175757 17 Q06124,Q9Y5X3,Q9H1E3,P78356 4 +Regulation of multicellular organismal development 0.2323656076831099 0.3585423084753042 0.7199375118921316 1.0 0.9780961620175757 192 Q9H2J4,Q9C0E8,Q9UPY3,Q9GZS3,O43251,P09429,Q16539,Q00534,P55209,P04083,Q86VS8,Q96G23,Q9UQB8,P53990,O43379,P04792,O00203,Q9GZP4,P22392,O14617,Q13614,P46821,O15347,Q9UIW2,P07196,Q9P265,O75122,O95747,Q8N0X7 29 +Fibroblast apoptotic process 0.3870630653558742 0.3544421119836238 0.7230075795055724 1.0 0.979865535382552 6 Q9UEE9,Q9BZZ5 2 +Regulation of organelle assembly 0.2211379334135668 0.3541615767142317 0.7232177971089266 1.0 0.9799489657845928 66 Q16658,P26038,O75351,Q9NVG8,P15311,Q13131,Q4KMP7,P27816,O00560,P50570,P50395,Q9NZZ3,P27695,Q9UHD8,Q9UN86,Q14204,P42858,A5YKK6,P78356,P49841,Q9BPX3,Q92783,P35241,Q15042,Q9NT62,Q9HD42,Q15555,Q8TC07,Q13283,Q66K14,Q6UVJ0 31 +Vascular associated smooth muscle cell apoptotic process 0.4177579188053923 0.3520523903539434 0.7247989724797752 1.0 0.9802779701655064 5 Q53EL6 1 +Regulation of protein sumoylation 0.3400820279388856 0.3510411577260673 0.7255574713673743 1.0 0.9805127082900348 8 Q9UBE0,Q9UBT2 2 +Positive regulation of synaptic vesicle recycling 0.5474729769208426 0.3504958414689022 0.7259666105021714 1.0 0.9805127082900348 2 Q9Y263 1 +Response to type i interferon 0.2797852422508251 0.3504867594195016 0.7259734252321557 1.0 0.9805127082900348 19 P08238,Q16543,Q9Y3Z3,Q7Z739,Q06124,P51617 6 +Uv protection 0.440823863096906 0.3504699641108223 0.725986027675463 1.0 0.9805127082900348 4 P39748 1 +Cell morphogenesis 0.2307820931475892 0.3504330412527654 0.7260137331862349 1.0 0.9805127082900348 190 O75400,Q12955,Q06124,P15311,Q9UEE9,Q13043,Q9UPY3,O43251,P46108,P16949,Q16512,O60678,Q16539,Q6SZW1,Q02750,Q9BVA1,P04083,Q96AC1,O60271,Q9P258,O95487,Q9UNF0,Q9Y2J2,Q9UQB8,Q13596,Q16555,P78559,Q9Y4F1,Q13740,Q96PU5,P08238,P53990,P46109,P49841,Q15814,P83731,Q13177,O00203,Q8N8S7,P46934,Q00535,P46821,Q9Y5A9,Q9HCE1,Q04917,Q96HC4,P43034,Q9UIW2,P07196,Q9P265,O60749,Q6IBS0,Q8N0X7 53 +Cytokinetic process 0.2776498407295399 0.3497060523893894 0.7265593110006865 1.0 0.9810485411955192 20 Q9NZZ3,Q9HD42 2 +Positive regulation of hydrolase activity 0.2278691650341406 0.3488017368019662 0.7272381594302015 1.0 0.9817640685979702 102 Q8IV63,P42345,Q9NVG8,Q13526,P46108,P09429,Q8WU90,Q96HP0,Q9H6U6,Q96AC1,Q9P258,P23396,Q92688,P08238,P46109,P31751,P49841,O14737,P61289,O60343,Q15042,Q9UL46,O95831,Q15257,Q15555,O95999,Q8TC07,Q9Y3D6,Q66K14,P0DP25 30 +Bile acid and bile salt transport 0.5414962010520084 0.3481435802596874 0.7277323567369676 1.0 0.9820290062661392 3 Q13131,P28288 2 +Regulation of long term synaptic potentiation 0.3846146737444428 0.3459787625729233 0.729358675276673 1.0 0.9830714939972084 6 P49841,O95793,Q9BPZ3,Q92542 4 +Regulation of substrate adhesion dependent cell spreading 0.280561575826671 0.3453200472424269 0.7298537770504983 1.0 0.9830714939972084 18 Q96AC1,P46108 2 +Regulation of cytosolic calcium ion concentration 0.2573704915852557 0.3448585318824151 0.7302007270468533 1.0 0.9830714939972084 27 P0DP25,P62942,P28161,P42858 4 +Regulation of cellular amino acid metabolic process 0.5401380307531181 0.3444945338501597 0.7304744061183674 1.0 0.9830714939972084 3 O14874 1 +Basement membrane assembly 0.4380853090539862 0.342156345571366 0.7322332358405235 1.0 0.9831671970803548 4 O75122 1 +Neuromuscular process 0.2456455935902506 0.3420617122859418 0.7323044504952279 1.0 0.9831671970803548 30 Q9GZZ9,P28161,Q9HCK8,P07196,Q14203,O43251,P78559,Q8N0X7 8 +Vitamin biosynthetic process 0.5385739333722908 0.3403163552818099 0.7336183017041611 1.0 0.983988669914659 3 O00764,Q9Y617 2 +Water soluble vitamin biosynthetic process 0.5385739333722908 0.3403163552818099 0.7336183017041611 1.0 0.983988669914659 3 O00764,Q9Y617 2 +Regulation of metal ion transport 0.2226146323265873 0.340288739313288 0.7336390964408426 1.0 0.983988669914659 62 P42858,P17931,P62942,Q9H4A3,O95747,P0DP25,P27695,Q00535,P28161,Q9UKS6,Q12955,O43865,Q04917,Q9UHD1,P17612,P46934,Q96PU5 17 +Pallium development 0.231816001922033 0.3400239891157218 0.733838462414522 1.0 0.983988669914659 42 Q00534,P46109,P49841,O43379,P43034,Q13144,P07196,P46108,Q96P11,Q00535 10 +Positive regulation of lymphocyte migration 0.4137434794232734 0.3392516557897141 0.7344201583865604 1.0 0.9840732766945046 5 O95747 1 +Positive regulation of t cell migration 0.4137434794232734 0.3392516557897141 0.7344201583865604 1.0 0.9840732766945046 5 O95747 1 +Regulation of peptidase activity 0.2266975958338123 0.3391826131317335 0.7344721664649518 1.0 0.9840732766945046 83 Q99497,P98170,O43847,P30086,P61201,P09429,Q96K76,P23396,P30740,Q92688,P78318,P25788,P04080,P06744,P20810,Q13177,Q9C0C9,O14737,P61289,Q9UL46,O95831,O95999,Q15392,Q9Y3D6,Q04323 25 +Transcription coupled nucleotide excision repair 0.4370067231803696 0.338907942025386 0.7346790812825628 1.0 0.9841504783203928 4 P18074,Q93009,P19447 3 +De novo pyrimidine nucleobase biosynthetic process 0.382159304334026 0.3375798046614836 0.7356798631938137 1.0 0.9845959425532984 6 P11172 1 +Negative regulation of mitochondrion organization 0.2770707858315018 0.3369357597065894 0.7361653274952864 1.0 0.9847406328833052 19 Q96E52 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.3197215724599784 0.3364698160364981 0.7365166093839792 1.0 0.984752267988322 10 Q9UNH7 1 +Negative regulation of peptidase activity 0.2320283577970742 0.335852082637292 0.7369824127169686 1.0 0.984752267988322 41 P04080,P06744,Q96K76,Q99497,P20810,P98170,Q15392,Q13177,P30086,Q9C0C9,P61201,P30740,P78318,Q04323 14 +Mitotic spindle organization 0.2207399735087719 0.333923741052017 0.7384371042950482 1.0 0.984752267988322 71 Q15018,O43670,O75351,Q9NZZ3,Q9HBM1,Q15813,Q9P287,P33981,O43379,Q9Y266,O75122,P16949,Q9HD42 13 +Mitotic spindle assembly 0.232434900269311 0.333596152766186 0.7386843217629462 1.0 0.984752267988322 40 Q15018,O43670,Q9NZZ3,O75351,Q9P287,O75122,Q9HD42 7 +N acetylneuraminate metabolic process 0.4352114356804786 0.3335338794960797 0.7387313199073273 1.0 0.984752267988322 4 Q9UJ70 1 +Negative regulation of innate immune response 0.2811516193816212 0.333161525480566 0.7390123588801925 1.0 0.984752267988322 16 P19474,P39019,Q9Y3Z3,Q7Z739,P46108 5 +Protein maturation 0.2221199834500487 0.3307372870540913 0.7408429348399288 1.0 0.986194795328112 74 P62942,Q86UY6,Q15392,Q5VZE5,Q96E52 5 +Dna templated transcription elongation 0.2294994439090384 0.3295950089183618 0.7417059943692905 1.0 0.986945077691232 43 P18074,P55199,Q92541,Q9Y5B9,Q8WX92,Q14241,Q8IXH7,O95251,Q9GZS3,Q96QE5,P13984,Q15370,Q4G0J3,O43719 14 +Peptidyl lysine modification 0.2243258310585904 0.3287190081683457 0.7423680856269115 1.0 0.9873956281778132 107 Q96AQ6,Q96AY3,Q01105,Q86UY6,Q9UI30,Q92791,Q9UBL3,Q9GZS3,O96028,Q14012,Q9P265 11 +Positive regulation of mapk cascade 0.2239791370567415 0.3283850890571403 0.7426205156819299 1.0 0.9873956281778132 57 P09429,Q02750,Q13546,P46109,P98170,P36507,Q96AC1,Q06124,Q9UMX5,O60271,P14174,P23396,Q16512,P30046,O60504 15 +Positive regulation of production of mirnas involved in gene silencing by mirna 0.4101946006922202 0.3281159791547252 0.7428239726032078 1.0 0.9873956281778132 5 Q02750,Q13546 2 +Regulation of intracellular estrogen receptor signaling pathway 0.2927924121458172 0.3279224222538283 0.7429703198029054 1.0 0.9873956281778132 14 Q9GZZ9,Q86X55 2 +Hyperosmotic response 0.334040087767428 0.3274497283251103 0.7433277598511863 1.0 0.9873956281778132 8 P16989 1 +Membrane fusion 0.2300352556438546 0.3273638918203501 0.7433926733383627 1.0 0.9873956281778132 42 Q15075,O60763,Q9UN37,O60343,O95721,P78356,P31751,P04083,Q9UHD1,Q7Z6Z7,Q8WUH2,Q8IYU2 12 +Activation of protein kinase activity 0.2731272687154502 0.3270053139885298 0.743663866001117 1.0 0.98742682344562 20 Q02750,Q99497,Q9UER7,P42345,P05386,Q9H4A3,Q96M27,Q9H8V3,P51617 9 +Granulocyte differentiation 0.4096813464563365 0.3265197453199646 0.7440311526048096 1.0 0.98742682344562 5 O00203,P49327,Q14739 3 +Muscle cell cellular homeostasis 0.4092593325356704 0.3252099942638884 0.7450221451297871 1.0 0.987590254378689 5 P08237,Q9Y281,O95817 3 +Organ growth 0.2632460180162621 0.3250752940377228 0.7451240868765125 1.0 0.987590254378689 24 Q96HC4,Q16539,Q06124,P16989 4 +Regulation of carbohydrate metabolic process 0.2328648074596725 0.3244992090983363 0.7455601209409026 1.0 0.987590254378689 37 Q9BYT8,Q9UNI6,P85037,O14874,P18669,P49841,A6NDG6,Q13043,Q9NQ88 9 +Regulation of protein targeting to membrane 0.3097887012288177 0.3222776755327463 0.7472423440091949 1.0 0.9893194480234208 11 Q9UHD1,Q12955,Q00535,P31751 4 +Histone phosphorylation 0.2596105649909248 0.3213664492949043 0.7479327053224614 1.0 0.9897120424889606 25 Q8IV63,Q9Y4B6,Q9NY27,Q13043,P24941,O14965,O43823,Q16512,Q99986,Q00535 10 +Positive regulation of catabolic process 0.2177052815539486 0.3213656333607305 0.747933323579483 1.0 0.9897120424889606 169 Q9UJY5,Q99497,Q9HCE5,Q96C86,O43847,Q86W50,Q92995,Q9UNN5,Q969T7,P15311,Q96J02,P67809,Q15370,Q86YR5,P09429,P19474,P48729,P62333,Q5TAX3,Q13596,Q13137,Q96PU5,P42858,P78356,P31751,P49841,O95817,O75832,Q9NZJ0,Q9UKS6,Q15042,P46934,Q7Z6Z7,Q8TDB6,Q92879,Q9HCE1,Q7Z739,Q9Y2L1,P54725,Q9NPI6,Q8IYU2 41 +Regulation of b cell proliferation 0.377320033495799 0.3212917743174744 0.7479892893932041 1.0 0.9897120424889606 6 Q16512 1 +Synapse assembly 0.2736288025193097 0.3200781280085262 0.7489091054934072 1.0 0.9907181710612244 19 P46821,P46109,Q9NUL3,Q96HC4,Q04637,Q9Y4F1,Q00535 7 +Homologous chromosome segregation 0.3091330533461708 0.3196298325563562 0.7492489566890665 1.0 0.9907181710612244 11 Q92791,Q14674 2 +Positive regulation of cell substrate adhesion 0.2528896355397114 0.3195877249654656 0.7492808808076379 1.0 0.9907181710612244 27 Q00534,P46109,P49841,Q96AC1,Q13043,P46108 6 +Mrna modification 0.2782598652798594 0.3194954387451405 0.7493508496528012 1.0 0.9907181710612244 16 Q9HCE5,Q86W50,Q8WWH5,Q96PZ0,Q9UJA5 5 +Inositol lipid mediated signaling 0.2714136723433843 0.318574660205853 0.7500490712206007 1.0 0.9910406129160716 20 P46934,P42356 2 +Nucleotide phosphorylation 0.2322605320407479 0.3175755178091674 0.7508069474121088 1.0 0.991251631752578 36 P60174,P15531,P85037,P06744,P54619,P00338,P18669,P36871,Q01813,P08237,Q9BRR6,P00558,Q13131,P23919,P14618,P22392,Q9NQ88,P51570 18 +Establishment of protein localization to mitochondrial membrane 0.274699169754353 0.3168469728736066 0.7513597198689634 1.0 0.9915842389141556 18 O14737,P0DP25 2 +Erythrocyte homeostasis 0.2284438525458857 0.316211951366674 0.7518416369410068 1.0 0.9919417781036052 42 Q9GZZ9,Q16539,P06744,Q00534,O43251,Q6NYC1,P08708 7 +Regulation of cell size 0.2246020604817195 0.3155464251133086 0.7523468078906317 1.0 0.9920924500130114 48 P46821,P08238,P53990,P49841,P43034,P15311,Q9P265,Q6IBS0,Q96B36,Q16555,Q8N0X7,Q00535 12 +Negative regulation of phosphorus metabolic process 0.2252507354873703 0.3141715341293238 0.753390761373133 1.0 0.9926520828334834 98 Q99497,P62942,P30153,O43768,P42771,Q96B36,Q16512,O95429,P31946,Q9NYB0,Q9NY27,P31689,Q53EL6,O60271,Q9UNH7,Q96KB5,O95373,P78356,P46109,P49841,Q13177,P04792,Q04637,Q9UHD1,Q96SZ6,P51452,P0DP25,Q9NQ88 28 +Double strand break repair 0.2253610461389366 0.3141185265528955 0.7534310190192723 1.0 0.9926520828334834 97 Q9Y248,Q96FZ2,Q99504,P15927,Q9H1E3,P53041,P09429,Q9H4L7,Q96T76,Q15645,Q9NYB0,Q9Y3Z3,Q9NY27,Q9NWV8,Q9UNS1,O96028,O60921,P33991,P39748,Q96FW1,P35244,Q8TDB6,Q9BRT9,Q7Z4V5,Q9Y620 25 +Membrane docking 0.2409557616741675 0.3137958727922817 0.7536760792160608 1.0 0.9926520828334834 30 Q7Z6M1 1 +Mhc class ii biosynthetic process 0.5340344726847934 0.3137128349031186 0.7537391517091863 1.0 0.9926520828334834 2 Q96EB6 1 +Positive regulation of behavior 0.5283459964932652 0.3136438769699077 0.7537915308400873 1.0 0.9926520828334834 3 Q92769,Q96QK1 2 +Regulation of striated muscle contraction 0.3011561992527168 0.3135994303133954 0.7538252922731217 1.0 0.9926520828334834 12 P28161 1 +Ensheathment of neurons 0.2516771673653124 0.3128931603235574 0.7543618341389391 1.0 0.9927969473325584 27 Q13614,P49770,P31751,Q9UPY3,Q13144,Q9Y2J2,Q96P11 7 +Negative regulation of phosphorylation 0.2228457852427031 0.312374627730707 0.7547558304502027 1.0 0.9927969473325584 80 Q99497,P30153,P42771,Q96B36,Q16512,Q9NYB0,Q9NY27,P31689,O60271,Q53EL6,Q9UNH7,Q96KB5,O95373,P78356,P46109,Q13177,P04792,Q9UHD1,Q96SZ6,P51452,P0DP25,Q9NQ88 22 +Regulation of lipid transport 0.2657794986502715 0.3118771724760175 0.7551338715659499 1.0 0.9927969473325584 22 P31751,O15260,Q06124,O95486,P14174 5 +Microtubule nucleation 0.2765938224065279 0.3117318147039726 0.7552443472808634 1.0 0.9927969473325584 16 P23258,Q14203,O75122,Q16512,Q7Z460 5 +Positive regulation of oxidative stress induced cell death 0.4277667221983999 0.311695046351053 0.7552722929857394 1.0 0.9927969473325584 4 Q99497,Q13546 2 +Regulation of gliogenesis 0.2947952629262899 0.3109021271420392 0.7558750273372512 1.0 0.9929709406550736 13 Q96G23 1 +Tyrosine phosphorylation of stat protein 0.3740859900555591 0.3106076071707966 0.7560989433783831 1.0 0.9930600107816726 6 P07948,P22059,P30153,Q00613,Q92769 5 +Microtubule based process 0.2512135165434904 0.3100736306897091 0.7565049643375459 1.0 0.9932046853043424 245 Q15018,Q15691,P30153,O75351,Q9H6D7,P33981,P15311,Q9Y266,Q14203,P24941,Q13526,P16949,Q16512,Q96CS2,Q9BVA1,Q9HC35,Q9NZZ3,Q15813,Q9HBM1,Q9Y678,Q15004,Q86VS8,Q14674,Q9Y6G9,P07437,P78559,P23396,Q8TD16,A0AVF1,P78318,Q92572,P42858,O43670,P41208,P49841,Q8IWJ2,Q12873,O95817,O43379,P04792,O00203,Q9BUF5,Q9NZ32,Q9UHD1,Q9BV86,O14617,O43237,Q00535,Q9HD42,P46821,Q15555,Q8IWC1,Q96RL7,Q9P287,P61758,Q86Y56,O95067,P43034,P07196,O75122,Q6UVJ0,Q7Z460 62 +Regulation of phosphorus metabolic process 0.2578975849435356 0.3094807457436425 0.7569558564268306 1.0 0.9934957109289938 265 Q96A49,Q8IV63,Q99497,P62942,O75874,P30153,Q9H2J4,O43768,Q99570,P51114,P36507,P33981,Q5H9R7,P42771,Q06124,Q13043,P35080,Q13526,Q96B36,Q93062,P51617,Q16512,O43823,O95429,P31946,Q02750,Q9H4A3,Q9NYB0,Q16543,P23396,Q9NY27,Q96AC1,Q14738,P31689,Q53EL6,O60271,Q9UNH7,Q14012,P14174,Q9Y4R8,Q15435,Q96KB5,O60921,Q05639,P78318,Q9UNI6,Q96C90,P42858,P08238,Q86Y37,O95373,P78356,P31751,P46109,P49841,Q96M27,Q13177,P04792,O75832,Q9UHD1,Q13546,Q00535,Q13614,O95999,P18669,Q96SZ6,Q9P287,O95067,P10398,P51452,P0DP25,Q9NQ88 72 +Epithelial cell proliferation 0.2233958997961359 0.3091885711144655 0.7571780871970211 1.0 0.9934957109289938 51 P09429,P15531,Q00534,Q9H2J4,O95747,P22392 6 +Ruffle organization 0.2745034337679488 0.3085302418607996 0.7576788921732103 1.0 0.9936998100060608 17 P42345,P62330,P07737,Q9P258,P35241,P35080,O95429 7 +Mitochondrial transcription 0.3504210340497891 0.3063310759671164 0.7593525805654173 1.0 0.9949616798026696 7 Q00059,Q9BSK2,Q96QE5 3 +Protein localization to phagophore assembly site 0.3722781187447366 0.3047066987762005 0.7605895472091506 1.0 0.9959885369890188 6 P50851,Q8NEB9 2 +Peripheral nervous system myelin maintenance 0.4250219234142291 0.3038286499217247 0.7612584384280578 1.0 0.9965204207505812 4 Q8N3R9,Q92597,P31751 3 +Hematopoietic stem cell differentiation 0.2871942020520382 0.3036549378839746 0.7613907921539829 1.0 0.9965204207505812 14 P18074,Q9Y5A9,Q00534,Q96PZ0,P13010,Q96J02,P19525 7 +Positive regulation of cell matrix adhesion 0.2986546064268393 0.3035782351106024 0.7614492353338407 1.0 0.9965204207505812 12 P49841,Q96AC1,Q00534 3 +Regulation of receptor catabolic process 0.401044170369464 0.3002119167504084 0.7640155158284905 1.0 0.9986893278487824 5 Q13614 1 +Regulation of cell differentiation 0.2455244477956369 0.2997902791683804 0.7643371305930378 1.0 0.9987938636376124 232 P30153,Q06124,Q13043,P67809,Q16539,P04083,Q53EL6,O60271,Q96G23,Q14012,Q9UQB8,Q86TU7,Q13546,Q00535,P00491,P43034,Q9UIW2,Q86X55,Q9P265,Q15051,Q7Z460,Q8N0X7,Q96A49,Q9HCE5,Q9C0E8,O95251,Q9GZS3,P46108,Q9P258,Q16555,Q92688,P08238,P53990,P39019,O43379,O00203,Q04637,Q9GZP4,Q9Y5A9,O15347,Q9BXW9,Q96SZ6,Q04917,Q96PZ0,O75122,O14965,P17931,P42345,Q8N4Q0,Q9UPY3,Q96J02,P09429,P55209,P27695,Q86VS8,Q96AC1,P13010,P17612,P19525,P46109,Q16706,P22392,Q99873,O14617,P46821,Q9UQ80,Q9NUL3,P07196,O95747,P06493,Q9BYT8,O15144,O00299,P61981,O43251,Q00534,Q02750,P49841,Q8WX92,Q6IBS0 80 +Negative regulation of cell cycle 0.2221981619584088 0.2993510545847627 0.764672203523187 1.0 0.998800746589364 105 Q9UN37,P33981,P42771,Q06124,P15927,P24941,Q16539,Q96K76,Q00534,Q15645,Q9NVH2,Q13535,Q53EL6,Q14674,Q9UNS1,Q9Y6G9,O60921,O95373,O43670,Q969U7,Q96RU2,Q9NZJ0,Q00535,P41227,Q96SZ6,Q96DY7 26 +Basement membrane organization 0.3702249686102604 0.2980684624485038 0.7656509114312926 1.0 0.998995633817167 6 O75122 1 +Positive regulation of protein targeting to membrane 0.3099576494180409 0.2976431249363266 0.7659755565371236 1.0 0.998995633817167 10 Q9UHD1,Q12955,Q00535,P31751 4 +Transmission of nerve impulse 0.3475706434458271 0.2964644866463507 0.7668753841217777 1.0 0.998995633817167 7 P43034,Q12955 2 +Negative regulation of cysteine type endopeptidase activity 0.2602827724143889 0.2963059431399248 0.7669964476691633 1.0 0.998995633817167 23 P06744,Q96K76,Q99497,P20810,P98170,Q15392,Q13177,P61201,P78318 9 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5206628267442097 0.2943689809624377 0.7684759669937187 1.0 0.9998960712392542 3 A2RRP1 1 +Regulation of presynapse organization 0.3988636657314024 0.293739246802046 0.768957161941104 1.0 0.9999932159234084 5 Q04637,Q9Y4F1 2 +Vesicle localization 0.2176365134609584 0.2933371533630367 0.7692644577408227 1.0 1.0 61 Q658Y4,P42858,Q9UN37,O60763,Q9NR31,O75351,Q00535,O00203,Q92783,P43034,O75122,Q92905,O14617,Q92572,O95721 15 +L ascorbic acid metabolic process 0.5201636469900515 0.2931398241225866 0.7694152778573307 1.0 1.0 3 P78417,P14550 2 +Hindbrain development 0.2290357094749504 0.2929808227955557 0.7695368100293596 1.0 1.0 34 Q02750,P46109,O95456,Q06124,O95487,Q9UKA9,O43251,P46108,Q00535 9 +Dna replication 0.208680635956736 0.2927964967168845 0.7696777061827738 1.0 1.0 126 Q9Y248,P30153,Q99543,Q9UNN5,P49736,O95251,P40938,Q5W0B1,P15927,Q9H1E3,P24941,P40937,P49321,P49643,Q01105,P55209,Q08945,Q7L590,Q9Y5B9,Q9Y3Z3,Q15004,Q13535,Q9UBD5,Q9UNS1,P33991,P39748,Q07864,P49642,P31350,P46063,P35244,O43913,Q04837,Q96QE5,Q9NZJ0,P18858,Q9UFC0,P49427,P56282,Q9BRT9,P33316,P38935,P25205,P06493 44 +Ribosomal small subunit export from nucleus 0.3460755254961496 0.29134743612246 0.7707856113894307 1.0 1.0 7 P62826,P62841,Q96GA3 3 +Response to hormone 0.228689184901019 0.2913309546993507 0.7707982152512227 1.0 1.0 195 Q9GZZ9,Q96A49,Q5VZ89,O75874,Q14232,Q06124,Q9Y266,Q9H1E3,Q9UBL3,O43251,P46108,O43823,Q16512,Q16539,Q96T76,Q13243,Q9NR50,P04083,Q9UQB8,Q92572,P06744,P78356,P49841,P42785,P40818,O43865,P04150,O60343,P46934,P43490,Q9Y5X3,O95831,P17174,P46821,O60763,P49770,Q15392,P21266,P48163,Q13144,Q86X55,Q13309,P07196,P0DP25 44 +Positive regulation of intracellular signal transduction 0.2092617525300031 0.2913240335777042 0.770803508068322 1.0 1.0 158 Q13325,Q99497,P62942,P98170,P36507,Q06124,Q9UMX5,P63241,P51617,P53041,Q16512,O95429,P30046,P09429,P19474,Q02750,P62841,Q9NYB0,Q9NUD5,Q96AC1,Q13535,Q53EL6,O60271,Q9Y6G9,Q9Y4R8,P14174,P23396,O60504,P46109,P29692,P46934,Q13546,P62081,Q15555,O95999 35 +Positive regulation of mitochondrion organization 0.2538078167779483 0.2911535861665572 0.77093385836732 1.0 1.0 25 Q8N2A8,P42858 2 +Spinal cord motor neuron differentiation 0.5192869666861332 0.2909880382845962 0.7710604679256887 1.0 1.0 3 Q6Y7W6,Q9ULW3 2 +Cell differentiation in spinal cord 0.5192869666861332 0.2909880382845962 0.7710604679256887 1.0 1.0 3 Q6Y7W6,Q9ULW3 2 +Cellular response to reactive nitrogen species 0.3459068262616808 0.29077260461255 0.7712252388284087 1.0 1.0 7 P46108,O95831 2 +Response to nitric oxide 0.3459068262616808 0.29077260461255 0.7712252388284087 1.0 1.0 7 P46108,O95831 2 +Protein acetylation 0.2173173006030541 0.290748197521438 0.7712439068419104 1.0 1.0 61 Q96AQ6,Q01105,Q86UY6,Q5VZE5,Q9P265,Q14012 6 +Negative regulation of camp dependent protein kinase activity 0.5188625546895278 0.2899495020988382 0.7718548702510686 1.0 1.0 3 Q96EB6 1 +Erk1 and erk2 cascade 0.2252131060156704 0.2892262282247168 0.7724082619208128 1.0 1.0 41 P09429,Q8IV63,Q14152,Q02750,P46109,P36507,Q96AC1,Q06124,P51452,Q13526,P14174,P30046 12 +Gene silencing by rna 0.2218001137112424 0.2881604848426491 0.7732238949403936 1.0 1.0 45 Q02750,Q13546,P51114,Q5TAX3,Q9HCE1,P36507,Q04637,Q9UPY3,Q9HAV4,P62826,Q15631,Q99598 12 +Embryonic digit morphogenesis 0.3668118168537189 0.2871841768806862 0.7739713012786293 1.0 1.0 6 Q9C0E8 1 +Telencephalon development 0.2225646657546262 0.2871577198685748 0.773991558195354 1.0 1.0 44 Q00534,P46109,P49841,O43379,P43034,Q13144,P07196,P46108,Q96P11,Q00535 10 +Negative regulation of neuron differentiation 0.307164222369668 0.2869195815959416 0.774173896637802 1.0 1.0 10 P49841,O60271,P06730,Q15648 4 +Positive regulation of binding 0.216773519958101 0.2863571594808551 0.7746045831691144 1.0 1.0 61 Q15691,Q99497,P62942,O60869,Q13043,P62826,Q13526,P16949,Q86YR5,P09429,P19474,Q96D46,P15531,P08238,P49841,Q04637,Q00535,O15371,P0DP25 19 +Nadph regeneration 0.3132090107919771 0.2860682626042647 0.7748258389876943 1.0 1.0 9 Q9NQ88,P37837,P18669 3 +Ires dependent viral translational initiation 0.2941403400182834 0.2858830631897375 0.7749676862366552 1.0 1.0 12 O15371,Q14152,P41214,Q9ULC4,P55884,Q15366,O43583,O00303,P05455 9 +Ncrna catabolic process 0.2554851405151259 0.2855706385456981 0.775206994380909 1.0 1.0 24 Q9BQ61,Q9UPY3,Q5TAX3 3 +Protein autoubiquitination 0.2883521340948319 0.2846411638467789 0.7759190709977386 1.0 1.0 13 P19474 1 +Blood vessel morphogenesis 0.2215269319042 0.2840989279971105 0.7763345684690428 1.0 1.0 86 Q9H2J4,Q16539,Q96AY3,P04083 4 +Regulation of anion transport 0.2876071906690653 0.2816749867740445 0.7781927358571437 1.0 1.0 13 Q9HD26,O43865,P14174,Q15042,Q9Y4C2,Q13546 6 +Positive regulation of cell growth 0.2217544804424709 0.2816262378186 0.7782301193367096 1.0 1.0 44 O43598,P46821,Q96K76,P53990,Q7Z4V5,Q04637,P43034,O75832,Q6IBS0,Q96PU5 10 +Lymphocyte apoptotic process 0.2670640388973549 0.2813657399958453 0.7784298926224111 1.0 1.0 18 P24390,P17931,P46109,O95999,P14174,Q16512,Q13546 7 +Glandular epithelial cell differentiation 0.3429657460717685 0.280834736537302 0.7788371594224559 1.0 1.0 7 Q00534 1 +Regulation of response to dna damage stimulus 0.2196787705595546 0.2805066056237982 0.7790888582605029 1.0 1.0 81 Q99504,P51114,O95251,P15927,P09429,Q96K76,Q96T76,Q9NYB0,Q9NY27,Q13535,Q9UNS1,O96028,P14174,P23396,Q96FW1,O75832,Q96Q15,Q9UNS2,Q7Z4V5,Q9NQ88 20 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2216623564126783 0.2804432809243737 0.7791374353009075 1.0 1.0 89 Q16539,Q96B36,P04792,Q16512,P51452,Q9H1E3,Q9UNH7,Q9UQB8,P46108,P16949,P46934,P43490 12 +Extrinsic apoptotic signaling pathway 0.2205700938207074 0.2796622239660146 0.7797366631624789 1.0 1.0 45 Q99497,Q99504,P30153,P30154,P49841,O95999,Q9UNN5,Q13177,O95817,Q13043,P61289,Q13546,P42858 13 +Regulation of production of small rna involved in gene silencing by rna 0.3643557705572928 0.2794705988428649 0.7798836982040791 1.0 1.0 6 Q02750,Q13546 2 +Positive regulation of smooth muscle contraction 0.5205959684487441 0.2792213446143236 0.7800749641664817 1.0 1.0 2 Q14247 1 +Regulation of hexokinase activity 0.4159201016030783 0.2784815326291051 0.7806427394108055 1.0 1.0 4 Q9UNI6 1 +Response to human chorionic gonadotropin 0.5200116856558707 0.2777754036751717 0.7811847734383406 1.0 1.0 2 P48507 1 +Substantia nigra development 0.2751455910993683 0.27775294773345 0.7812020126652695 1.0 1.0 15 P12277,Q16352,Q04917,P27348,P62258,P0DP25 6 +Neuron projection maintenance 0.5136554119461878 0.2773772618414741 0.781490439327176 1.0 1.0 3 P78559 1 +Regulation of signal transduction by p53 class mediator 0.2250839436139253 0.2772085727602397 0.7816199573740787 1.0 1.0 38 Q13535,P62081,O75832,Q9UNS2 4 +Multicellular organism reproduction 0.2044372986739933 0.2764915599042116 0.7821705413111066 1.0 1.0 129 P30153,Q9HCE5,P42345,Q8N2A8,P33981,Q06124,Q14320,P62826,Q4G0J3,Q15645,Q5TAX3,P04083,Q9BPZ3,A0AVF1,Q15019,P16989,P46109,P41208,O00203,Q9BQA1,Q9GZP4,O60684,Q99598,Q92879,Q9Y5A9,Q9BXW9,Q96SB4,P54727,O95067,P43034,Q15102,O14965,O60879 33 +Regulation of histone h2b ubiquitination 0.3923976608187195 0.2749581234958402 0.7833484112822227 1.0 1.0 5 Q5VTR2,O75150,Q6PD62,Q9NW82 4 +Dendrite arborization 0.512565751022779 0.2747863532240477 0.7834803832094517 1.0 1.0 3 Q9NZI8,O14786 2 +Protein localization to microtubule 0.3100123203816278 0.2741204434939742 0.7839920637147939 1.0 1.0 9 P78559,Q15555 2 +Postsynaptic modulation of chemical synaptic transmission 0.4139870131602449 0.2732473591453949 0.7846630772775003 1.0 1.0 4 P40818 1 +Rna splicing via endonucleolytic cleavage and ligation 0.5112665590915083 0.2717154779841507 0.7858407991930061 1.0 1.0 3 Q9Y224 1 +Cdc42 protein signal transduction 0.5108123904149465 0.2706466620387586 0.7866628035853525 1.0 1.0 3 P60953,O14786 2 +Regulation of bmp signaling pathway 0.2962602548828429 0.2696635476691686 0.787419106654196 1.0 1.0 11 Q8N0X7 1 +Positive regulation of ion transport 0.2207180247016948 0.269183372240118 0.787788575215514 1.0 1.0 43 Q9H4A3,P28161,Q12955,O43865,Q9UHD1,P14174,Q15042,P0DP25,P42858 9 +Response to platelet derived growth factor 0.3085480093676807 0.2687230733853849 0.7881427946823563 1.0 1.0 9 P56192,Q765P7,Q96A49,P22681,Q13547,P07947,P35241,P46940 8 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3023127993267313 0.2687203251465211 0.7881449097002331 1.0 1.0 10 P63241,P62081 2 +Mitotic metaphase plate congression 0.2328607544760543 0.2675408275426548 0.7890527835690277 1.0 1.0 30 Q9UN37,Q9NZZ3,O75351,Q9Y266,Q9HD42 5 +Immune effector process 0.2167354251203104 0.2653625532707408 0.790730180518473 1.0 1.0 78 P09429,Q9UQ84,P04083,O96028,P13051,Q9UNH7,P46108,Q16512 8 +Cytoplasmic translational elongation 0.359624451098289 0.2648965208504143 0.7910891785863274 1.0 1.0 6 Q9BTV6,P05387 2 +Regulation of microvillus length 0.5076608522585331 0.2632973226749271 0.792321423106394 1.0 1.0 3 Q6IBS0 1 +Negative regulation of transferase activity 0.2146520031300847 0.2600977507047555 0.7947883729124623 1.0 1.0 75 O95373,P62081,Q99497,P62841,P78356,P49841,Q9UHD1,Q96SZ6,Q13177,P42771,P04792,P31689,Q53EL6,P51452,Q9UNH7,Q96B36,Q16512 17 +Endocytic recycling 0.2501101795242982 0.2596051931463355 0.7951683300946315 1.0 1.0 24 Q96L92,Q9UMY4,O75436,Q15036,O60493,Q9UID3,P62330 7 +Neurotransmitter receptor localization to postsynaptic specialization membrane 0.5118317265556687 0.2580126779755951 0.7963971228048885 1.0 1.0 2 Q15334 1 +Ribonucleoprotein complex localization 0.3571219654869726 0.257342561995499 0.7969143387902844 1.0 1.0 6 P12270,Q7KZ85,Q8WWY3,Q96ST2,Q08J23 5 +Positive regulation of muscle hypertrophy 0.3352837916910473 0.2556406984498106 0.7982282895035686 1.0 1.0 7 P58546,P50750,O75116,P17252,Q13464,Q12792 6 +Protein monoubiquitination 0.2465816514640644 0.2554615377639337 0.7983666466761663 1.0 1.0 25 P19474,Q13620,Q14258,Q9NZJ0,O75150,P63208,Q9C0C9,Q5W0B1,Q86UK7,Q7Z6Z7,Q8TDB6 11 +Postsynaptic signal transduction 0.3851470257845299 0.2546515167274124 0.7989922659041913 1.0 1.0 5 P46109 1 +Regulation of cytoplasmic translational initiation 0.4068827602400965 0.2544722034668902 0.7991307758468014 1.0 1.0 4 P42345,Q9Y5A9 2 +Negative regulation of cytoskeleton organization 0.2158994844984405 0.2536409849256508 0.7997729303860261 1.0 1.0 48 O75122,P46821,Q15691,P47755,Q13177,Q9BPX3,P07737,P60983,P35241,P35080,Q9NUQ9,Q02790,Q6IBS0,P16949,Q13045,Q7Z460,P04350 17 +Regulation of translational elongation 0.3337441973124571 0.2507273346856894 0.802024925552618 1.0 1.0 7 P63241,Q9BTV6,Q9BQC3 3 +Regulation of membrane potential 0.2121071351180548 0.2496990645883624 0.8028200816430249 1.0 1.0 61 Q13614,Q99808,Q99497,Q9BSK2,P31751,Q9H2U2,P49841,P0DP25,Q00535,Q04917,Q12955,Q9UQB8,Q15042,P46934,Q8N0X7,Q96PU5 16 +Substrate adhesion dependent cell spreading 0.252146688417494 0.2475271204553842 0.8045003052909796 1.0 1.0 22 Q96AC1,P46108 2 +Regulation of neuron differentiation 0.2449093364516976 0.2475196470175001 0.8045060883330462 1.0 1.0 25 P46821,P49841,Q96SZ6,Q15648,P61981,O43379,Q04637,Q04917,O60271,Q16555 10 +Dna modification 0.2252454604599241 0.2463126116111212 0.8054402479855316 1.0 1.0 31 Q01804,Q8N2A8 2 +Meiotic chromosome separation 0.3531512473587946 0.2455802784884615 0.8060071572681167 1.0 1.0 6 Q14674 1 +Regulation of amyloid precursor protein catabolic process 0.2673446325951565 0.2455796778821651 0.8060076222477119 1.0 1.0 15 P62942 1 +Positive regulation of embryonic development 0.3111680125040802 0.2446535784852957 0.8067246747780443 1.0 1.0 8 P23528,P43034,O95747 3 +Cell cycle checkpoint signaling 0.2095990293961892 0.2435528889344975 0.8075771187903451 1.0 1.0 64 Q16539,Q9UN37,O43670,Q15645,Q9NVH2,Q969U7,Q96RU2,P33981,Q13535,Q06124,P15927,Q9UNS1,P24941,Q9Y6G9,Q9NZJ0,O60921 16 +Regulation of hematopoietic stem cell differentiation 0.2952262039274735 0.2431377375227919 0.8078986978657143 1.0 1.0 10 Q9Y5A9,Q00534,Q96PZ0,Q96J02,P78527,P19525 6 +Positive regulation of mitotic cell cycle 0.2143466339434195 0.243135765308833 0.8079002256334231 1.0 1.0 49 P06730,P31350,O75351,P04083,P27695,Q96DY7,Q04637,Q06124,P43034,Q14674,Q9P258,P51452,Q9NZJ0,Q6UVJ0,P08243,P06493 16 +T cell mediated immunity 0.3013398849516094 0.2428652401339899 0.8081097938251898 1.0 1.0 9 P09429,Q9NUQ9 2 +Response to nitrosative stress 0.3517523003921534 0.2415024382470272 0.8091657269557571 1.0 1.0 6 P31689 1 +Cell cell adhesion 0.2168716672390237 0.240265091369295 0.8101247555055426 1.0 1.0 102 Q12955,Q06124,P15311,Q15417,Q96J02,P51617,P09429,Q16539,Q96JJ3,Q9H4A3,P04083,Q9UQB8,P23396,Q13740,Q13630,P04792,O00203,Q9NUQ9,O14617,Q9Y5A9,P00491,O95999,Q96HC4,P51452,O75190 25 +Ump biosynthetic process 0.3506873354781981 0.2384214896522821 0.81155420159856 1.0 1.0 6 P11172,Q05682,P27708,Q02127,Q9BZX2 5 +Pyrimidine ribonucleoside monophosphate metabolic process 0.3506873354781981 0.2384214896522821 0.81155420159856 1.0 1.0 6 P11172,Q05682,P27708,Q02127,Q9BZX2 5 +Maintenance of cell polarity 0.3296992799056872 0.2380402309918821 0.8118498910383689 1.0 1.0 7 P49841,O14745 2 +Bergmann glial cell differentiation 0.3786099539740271 0.2370473070345763 0.8126200902284904 1.0 1.0 5 Q02750 1 +Regulation of adherens junction organization 0.4955609855530306 0.2361902957231925 0.8132850094136583 1.0 1.0 3 P35241 1 +Regulation of chondrocyte differentiation 0.3770042367006595 0.2328274241434975 0.815895416667628 1.0 1.0 5 Q9C0E8 1 +Regulation of cartilage development 0.3770042367006595 0.2328274241434975 0.815895416667628 1.0 1.0 5 Q9C0E8 1 +Positive regulation of meiotic cell cycle 0.4929413991061664 0.2305571666436507 0.8176588471424469 1.0 1.0 3 P30307 1 +Regulation of osteoblast differentiation 0.2976318371170756 0.2300357572800766 0.8180639843793642 1.0 1.0 9 Q96AC1,P17612,Q00534 3 +Pigment granule localization 0.3757309941520488 0.2295108815318046 0.8184718640932176 1.0 1.0 5 Q96AX1,Q13561,P62820,Q9H267 4 +Regulation of immunoglobulin production 0.2559479167067741 0.2275493353648661 0.8199966111213592 1.0 1.0 17 Q16512,O96028 2 +Presynapse organization 0.3258097883063012 0.2261482538654202 0.8210861154189668 1.0 1.0 7 Q04637,P62330,Q9Y4F1 3 +Methylation 0.2086939903938446 0.2261185924761582 0.8211091843482621 1.0 1.0 118 Q92541,Q9UI30,Q8N2A8,Q9NXH9,O60678,Q9UBP6,Q6P2P2,Q9HBK9,Q86X55,O96028,Q9UBL3,Q9GZS3,Q8IZ69,Q9C005,Q969Y2,Q9BV86 16 +Histone exchange 0.4907265658125647 0.2258606551394309 0.821309799752663 1.0 1.0 3 P49321 1 +Organic acid biosynthetic process 0.2118486623716277 0.2245018720199071 0.822366810429322 1.0 1.0 78 P04083,P00374,Q13126 3 +Negative regulation of endocytosis 0.2718673652262893 0.2225827290343929 0.8238602794955294 1.0 1.0 13 Q9UKS6,Q13614,P17931,Q9UNF0 4 +Acute inflammatory response 0.3729987941355621 0.222482959812759 0.8239379369812907 1.0 1.0 5 P42785 1 +Cell communication by electrical coupling involved in cardiac conduction 0.3729367905758421 0.2223248848817495 0.8240609814791953 1.0 1.0 5 P17612,P0DP25 2 +Negative regulation of catalytic activity 0.2133896787419738 0.2217820444559201 0.824483557840278 1.0 1.0 176 Q99497,Q14558,P62942,P98170,O43768,P30086,P42771,P61201,Q96B36,Q16512,O95429,Q86YR5,P31946,Q96K76,Q01105,P62841,Q9H4A3,P04083,Q9H6U6,Q9NX74,P31689,Q53EL6,Q9P258,Q9UNH7,P30740,P78318,O43924,P04080,Q96C90,P06744,O95373,P20810,P78356,P49841,Q13177,Q9C0C9,P04792,O00170,Q9UHD1,Q8TDB6,Q15257,P62081,Q9BTT0,Q96SZ6,Q15392,Q86VP6,P51452,Q9Y314,O75190,Q04323 50 +Monocyte differentiation 0.3242299825325369 0.2214055070085275 0.824776704856544 1.0 1.0 7 O00625 1 +Negative regulation of neuron apoptotic process 0.2305483256727393 0.2207341141024257 0.825299467339583 1.0 1.0 28 P06744,Q01105,Q9UNH7,P51858 4 +Response to leucine 0.37225804041268 0.2205985657650147 0.8254050179059562 1.0 1.0 5 Q8NEB9 1 +Maintenance of apical basal cell polarity 0.4880187025131306 0.2202015687206912 0.8257141749503014 1.0 1.0 3 O75083,O14745 2 +Type i interferon production 0.2357806332208801 0.2179067840837147 0.8275017412245083 1.0 1.0 26 P19474,Q9NUD5,Q06124,Q13283,Q96J02 5 +Ruffle assembly 0.2652357662015156 0.2169596658550969 0.8282397782097914 1.0 1.0 14 P62330,P07737,Q9P258,P35080,O95429 5 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.2812215127729913 0.2164930845718558 0.8286034150666144 1.0 1.0 11 P49841,Q99497,Q13043,Q9UNN5 4 +Defense response to other organism 0.2042106472590618 0.2163337286244174 0.8287276198432956 1.0 1.0 160 Q9NVU0,Q13325,P98170,Q06124,Q96J02,P81605,P46108,P51617,Q16512,O43823,P09429,Q6SZW1,P19474,P04083,Q9Y3Z3,Q16543,Q9NUD5,Q9UN86,P07437,P14174,Q13137,Q96C90,P08238,O95373,P39019,Q13177,Q8TDB6,Q01804,Q9Y5A9,O15347,O95999,Q9HCE1,Q96SB4,Q7Z739,Q13283,Q13309 36 +Negative regulation of b cell apoptotic process 0.3914780506926814 0.216327098837241 0.828732787306681 1.0 1.0 4 O95999 1 +Cortical actin cytoskeleton organization 0.2405174948544546 0.2162755450833434 0.8287729701670061 1.0 1.0 24 Q9UN37,Q9Y490,Q5VSL9,Q9Y2A7,Q12959,Q13464,P15311,Q9NQW6,P27797,Q14651,Q15149,P51153,Q9Y2J2,Q9H8V3,O75116,Q8WUM4,Q00535,P11171,Q9Y613,O14920,P62330,Q9H0H5,Q15334 23 +Cytoplasmic pattern recognition receptor signaling pathway 0.2502063549750953 0.2159167263349705 0.8290526588824321 1.0 1.0 19 Q96J02,P98170 2 +Negative regulation of metaphase anaphase transition of cell cycle 0.2480196747179945 0.2137162279793964 0.8307683556137582 1.0 1.0 20 Q15645,O43670,Q9Y6G9,P33981 4 +Brain morphogenesis 0.3013515238408424 0.2125648504714745 0.8316663901147716 1.0 1.0 8 Q9UID3,P43034 2 +Regulation of b cell apoptotic process 0.368920289417179 0.2122197341881338 0.8319356117096042 1.0 1.0 5 O95999 1 +Heart process 0.2184616083717823 0.2107366601089151 0.8330927663088326 1.0 1.0 31 P28161,Q96PU5 2 +Regulation of innate immune response 0.2092116751143923 0.2094758417740286 0.8340767925130135 1.0 1.0 50 P09429,P19474,P08238,P98170,P39019,Q16543,Q9Y3Z3,Q13177,Q9NUD5,Q7Z739,Q06124,P46108,Q16512 13 +Respiratory burst 0.3669892954342005 0.2074565653647153 0.8356533105480459 1.0 1.0 5 P39019,P18669 2 +Muscle structure development 0.2131297375907479 0.2066044280545483 0.8363188017923124 1.0 1.0 102 Q9BYT8,Q16539,P85037,P62942,P16989,Q86TU7,P51114,Q7Z4V5,Q8IV08,Q16527,Q96HC4,P61201,Q53EL6,O60271,Q14012,O94966,P67809 17 +Histone h3 k4 methylation 0.2355741586897467 0.2054816700485748 0.8371958177348107 1.0 1.0 25 Q9GZS3,Q9UBL3 2 +Leukocyte proliferation 0.2125520392435648 0.2053826354025369 0.837273186040628 1.0 1.0 39 P09429,P04083,Q96J02,P14174,P23396,Q16512,P17812 7 +Cellular response to amyloid beta 0.3187321010428772 0.2053005658347544 0.8373373020017114 1.0 1.0 7 P49841,Q9UNH7 2 +Response to amyloid beta 0.3187321010428772 0.2053005658347544 0.8373373020017114 1.0 1.0 7 P49841,Q9UNH7 2 +Cellular response to estradiol stimulus 0.3660818713450138 0.2052396876495516 0.8373848631225527 1.0 1.0 5 Q96KR6,Q9Y230,Q00613,O95831 4 +Microtubule organizing center localization 0.2514644160207173 0.2052333107092156 0.8373898451456263 1.0 1.0 16 P43034,P15311,Q8TD16,O43237 4 +Hematopoietic progenitor cell differentiation 0.2137282492218216 0.2052205669680342 0.8373998012897701 1.0 1.0 33 Q00534,Q9Y5A9,Q9HCE5,Q9NPH0,Q9Y4E6,O00203,Q96PZ0,Q6NXE6,Q96J02,P13010 10 +Establishment of protein localization to plasma membrane 0.2354883245096903 0.2051136273129887 0.8374833497296401 1.0 1.0 25 Q9UJY5,Q4J6C6 2 +Tripeptide transport 0.4801285797778915 0.2042361746942859 0.8381689437648685 1.0 1.0 3 O15439,O14745 2 +Oligopeptide transport 0.4801285797778915 0.2042361746942859 0.8381689437648685 1.0 1.0 3 O15439,O14745 2 +T cell mediated cytotoxicity 0.3375649511999752 0.2021524226737742 0.8397975663815269 1.0 1.0 6 P04439,Q9NUQ9 2 +Polyketide metabolic process 0.478959672706001 0.2019376951712583 0.8399654325988475 1.0 1.0 3 P15121,P14550 2 +Aminoglycoside antibiotic metabolic process 0.478959672706001 0.2019376951712583 0.8399654325988475 1.0 1.0 3 P15121,P14550 2 +Tertiary alcohol metabolic process 0.478959672706001 0.2019376951712583 0.8399654325988475 1.0 1.0 3 P15121,P14550 2 +Response to molecule of bacterial origin 0.2098338923268251 0.2016296502930449 0.8402062636846859 1.0 1.0 43 P09429,Q16539,O95999,Q9NZZ3,Q53EL6,Q9NUQ9,O43823 7 +Positive regulation of mrna splicing via spliceosome 0.2492936400942441 0.2013784058691244 0.8404026989569762 1.0 1.0 17 P98179 1 +Regulation of retinoic acid receptor signaling pathway 0.384975153463897 0.2013123589545129 0.8404543393399733 1.0 1.0 4 P27797,A5YKK6,Q13573 3 +Mitochondrion distribution 0.384972492724144 0.2013063502566494 0.8404590374202929 1.0 1.0 4 O75153,P27695 2 +Positive regulation of neurotrophin trk receptor signaling pathway 0.485539000876442 0.2007302114019173 0.8409095352044278 1.0 1.0 2 Q7L576 1 +Regulation of neurotrophin trk receptor signaling pathway 0.485539000876442 0.2007302114019173 0.8409095352044278 1.0 1.0 2 Q7L576 1 +Regulation of mrna 3 end processing 0.2446767797215818 0.2004033373757489 0.8411651495850627 1.0 1.0 20 O43865 1 +Mitotic dna replication 0.269865157828329 0.199919848597753 0.8415432668646816 1.0 1.0 12 Q9BY42,P49736,Q9BRX5,P25205,P33991,P18858 6 +Wnt protein secretion 0.4837861524978268 0.1972569253054108 0.8436264856515492 1.0 1.0 2 Q96QK1 1 +Lamellipodium morphogenesis 0.3356829122828404 0.1972129465935735 0.8436608996540933 1.0 1.0 6 Q13596 1 +Amine biosynthetic process 0.315373939073611 0.1957738225555555 0.8447872001460524 1.0 1.0 7 Q99497,Q6QHF9 2 +Positive regulation of map kinase activity 0.2746743906397203 0.1952181102723089 0.8452222018649962 1.0 1.0 11 P14174,P23396,Q16512 3 +Histone h2a ubiquitination 0.2956323529874008 0.1948945295463465 0.8454755168669532 1.0 1.0 8 Q8TDB6,Q96FW1 2 +Cellular response to light stimulus 0.2152467764969824 0.1948278535680045 0.8455277161076344 1.0 1.0 31 Q13535,Q96KB5,P46934 3 +Golgi organization 0.2049622524945025 0.1944365965797214 0.845834036746512 1.0 1.0 60 P83436,P48729,P42858,Q02750,O60763,Q8IWJ2,P36507,Q9UP83,Q9UID3,O15260,Q9H6U6,O75122,Q9Y6Y8,Q7Z460,Q8IYU2 15 +Negative regulation of i kappab kinase nf kappab signaling 0.2952882645595412 0.1938560644412217 0.8462885865099341 1.0 1.0 8 Q96EB6,P61586,Q13547,P42224,Q14694,O60826,Q13546 7 +Cardiac chamber development 0.2443682475312683 0.1930611779708981 0.8469110561167699 1.0 1.0 19 O96028 1 +Regulation of dna binding transcription factor activity 0.2015393990516107 0.1919483233447205 0.8477826846041141 1.0 1.0 66 P19474,Q99497,O95999,Q9BXW9,Q9NYB0,P23396,Q92905,P42771,P60900,O75832,Q96J02,Q9UN86,Q9UHD1,P51617,P19525,O00221,Q13546,Q9UNN5 18 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.3599688818636654 0.1906658258098108 0.8487874145138912 1.0 1.0 5 Q9UPY3 1 +Golgi ribbon formation 0.3599415204678415 0.1906020134845033 0.8488374125816502 1.0 1.0 5 O14744,Q9H4A6,Q8IWJ2,Q08379 4 +Positive regulation of oligodendrocyte differentiation 0.3800058462437915 0.1902840280549172 0.8490865687629656 1.0 1.0 4 O14744,P42345,Q92769 3 +Regulation of protein import 0.2267538714196682 0.1901502301010537 0.8491914101096609 1.0 1.0 27 Q16539,O95817 2 +Regulation of protein containing complex disassembly 0.2064600895787084 0.1900256819761019 0.8492890058763343 1.0 1.0 45 P47755,P63241,Q12792,Q9Y281,P78559,Q13137,P48681,P15170,Q9BPX3,P35241,Q13045,P62495,P58546,P46821,P60981,Q9UEY8,Q6IBS0,O75122,Q9UHB6,Q7Z460 20 +Leukotriene transport 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 1.0 2 O15439 1 +Tripeptide transmembrane transport 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 1.0 2 O15439 1 +Dna synthesis involved in dna repair 0.2572730520232966 0.1891353716767935 0.8499867191811563 1.0 1.0 14 Q07864,P56282,P12004,Q15004,P40938,Q9NZJ0 6 +Secretion 0.2005515026910392 0.1877981404853315 0.8510348935113432 1.0 1.0 158 Q9UN37,Q99497,Q7Z6M1,O75351,O43768,Q06124,P61201,P15311,P35080,Q16512,P55327,Q9H4A3,P04083,Q9Y678,O95486,Q9UNH7,Q12765,P14174,Q15019,O95721,P15531,Q16850,P49841,Q86YV9,Q8NEB9,Q92783,Q4J6C6,Q15042,Q9Y5X3,P20645,Q00535,Q9UNS2,Q92905,P43034,O75122,P0DP25,Q7Z460 37 +Dna repair 0.2179889615564953 0.1874950134558505 0.8512725330498738 1.0 1.0 191 Q9Y248,Q96FZ2,Q99497,Q99504,Q9UQ84,O95251,Q9H1I8,P15927,Q9H1E3,P24941,P53041,P09429,Q96K76,Q9H4L7,Q96T76,Q08945,Q15645,Q9NYB0,Q9Y3Z3,Q8N3C0,Q15004,Q9NY27,Q13535,Q9UNS1,O96028,P23396,O60921,P33991,P39748,Q07864,Q96FW1,P41208,P54277,P35244,Q96RU2,Q9NZJ0,P18858,Q96Q15,Q9BRT9,Q7Z4V5,P54727,Q9P287,P38935,P13051,P54725,Q9NQ88,Q9Y620 47 +Polyamine biosynthetic process 0.3784739045521951 0.1869627215329572 0.8516898614230834 1.0 1.0 4 Q6QHF9 1 +Polyamine metabolic process 0.3784739045521951 0.1869627215329572 0.8516898614230834 1.0 1.0 4 Q6QHF9 1 +Ameboidal type cell migration 0.2091167163845545 0.1868353530907475 0.8517897271974202 1.0 1.0 83 Q13630,Q16539,P09429,P06744,Q15555,P04083,P42785,Q7Z739,P04792,P43034,Q06124,Q9H6U6,P07737,P35080,O75122,O95429,Q16512,Q7Z460 18 +Positive regulation of extracellular matrix organization 0.3581745359664615 0.1865079995873726 0.8520464061578297 1.0 1.0 5 O75122,Q7Z460 2 +Regulation of ion transmembrane transport 0.2013613057768957 0.1862348901077687 0.852260564193221 1.0 1.0 65 P42858,Q9HD26,Q99497,P62942,Q9H4A3,O95747,P0DP25,P27695,Q00535,P28161,Q04917,Q12955,O43865,Q9UHD1,P17612,P46934,Q13546,Q96PU5 18 +Antigen processing and presentation of exogenous peptide antigen 0.3578947368421092 0.185864594704048 0.8525509476934796 1.0 1.0 5 P04439,Q03518,P50570,O14920 4 +Fucose metabolic process 0.4687317358269851 0.182566859338351 0.8551378896662567 1.0 1.0 3 P04066,Q9BTY2 2 +Glucose metabolic process 0.2023299302272149 0.1821281453730994 0.8554821612986123 1.0 1.0 62 Q9BYT8,Q16539,P85037,Q9UNI6,P06744,O14874,Q96G03,P31751,P49841,A6NDG6,Q13043,Q96E52,Q9NQ88 13 +Positive regulation of dna binding transcription factor activity 0.2081649610996627 0.1816509764937539 0.8558566408522252 1.0 1.0 39 P19474,Q99497,O95999,Q9NYB0,P60900,P23396,Q92905,Q13546 8 +Protein localization to chromosome telomeric region 0.2412721104836214 0.1814760417384902 0.8559939368371883 1.0 1.0 19 Q9NYB0 1 +Adp metabolic process 0.2122922022693436 0.1807603272531697 0.8565557043310204 1.0 1.0 31 P60174,P06744,P85037,P54619,P00338,P18669,P36871,P08237,Q9BRR6,P00558,Q13131,P14618,Q01813,Q9NQ88,P51570 15 +Positive regulation of vascular permeability 0.4672706019871268 0.1799085776600245 0.8572243410820468 1.0 1.0 3 Q9UDY2,Q16625 2 +Positive regulation of blood brain barrier permeability 0.4672706019871268 0.1799085776600245 0.8572243410820468 1.0 1.0 3 Q9UDY2,Q16625 2 +Regulation of blood brain barrier permeability 0.4672706019871268 0.1799085776600245 0.8572243410820468 1.0 1.0 3 Q9UDY2,Q16625 2 +Dna dependent dna replication 0.2075843473321307 0.1778741273279638 0.8588218302038468 1.0 1.0 82 Q9Y248,P12004,P49736,O95251,P40938,P40937,Q9H1E3,P24941,P49643,Q7L590,Q9Y3Z3,Q13535,Q9BRX5,Q9UBD5,Q9UNS1,P33991,P39748,Q07864,P49642,P46063,O43913,Q04837,Q96QE5,P28340,P27694,P18858,P23921,Q9UFC0,P49427,P56282,P35251,Q9BRT9,P25205 33 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3738672902660021 0.1771997471708611 0.8593514942498917 1.0 1.0 4 P11940,A5YKK6,Q9H2U1 3 +Regulation of nuclear transcribed mrna poly a tail shortening 0.3738672902660018 0.1771997471708602 0.8593514942498923 1.0 1.0 4 P11940,A5YKK6,P62487 3 +Endocytosis 0.1934289288244343 0.1768060546950395 0.8596607330251471 1.0 1.0 131 Q9UBC2,Q7Z6M1,O15260,Q14677,Q6NYC1,Q15075,Q15036,Q9UNF0,Q13596,Q5T1M5,Q96PU5,P15531,Q8NEB9,Q9UKS6,P46934,Q9Y5X3,P20645,Q13614,Q8N6T3,O60749,P0DP25 21 +Regulation of mitotic centrosome separation 0.4729769208297002 0.1768043531676842 0.8596620695928328 1.0 1.0 2 P52732 1 +Negative regulation of cell growth involved in cardiac muscle cell development 0.4652250146113237 0.1762328984330911 0.8601109760351748 1.0 1.0 3 P49840,P11413 2 +Negative regulation of cardiac muscle tissue growth 0.4652250146113237 0.1762328984330911 0.8601109760351748 1.0 1.0 3 P49840,P11413 2 +Regulation of cell growth involved in cardiac muscle cell development 0.4652250146113237 0.1762328984330911 0.8601109760351748 1.0 1.0 3 P49840,P11413 2 +Response to l phenylalanine derivative 0.4652250146113231 0.1762328984330905 0.8601109760351753 1.0 1.0 3 P48507,P48506 2 +Response to thyroxine 0.4652250146113231 0.1762328984330905 0.8601109760351753 1.0 1.0 3 P48507,P48506 2 +Regulation of tumor necrosis factor mediated signaling pathway 0.2886913434802234 0.1744965762906362 0.8614752212165364 1.0 1.0 8 P98170 1 +Action potential 0.2391787999143124 0.1738571482917752 0.8619777303752671 1.0 1.0 19 P0DP25,Q96PU5 2 +Regulation of cell aging 0.2571333883860489 0.1738372035315115 0.8619934053220655 1.0 1.0 13 P67809,Q00534 2 +Regulation of endoplasmic reticulum tubular network organization 0.3521949150613158 0.1730493751699701 0.8626126172501494 1.0 1.0 5 Q9C0E8 1 +Mannose metabolic process 0.3717492677870618 0.1728243809342985 0.8627894721897098 1.0 1.0 4 P34949 1 +Leukocyte adhesion to vascular endothelial cell 0.3520467836257282 0.1727237637547339 0.8628685637538474 1.0 1.0 5 Q13464,Q9H4A6,P61586,P51617 4 +Rrna modification 0.2414758016824424 0.1726981405378991 0.8628887054672632 1.0 1.0 17 Q9UI30,Q96P11,Q96HR8 3 +Response to ether 0.3716286446512959 0.172577357120645 0.8629836512245208 1.0 1.0 4 Q6PKG0,P11802 2 +Spindle localization 0.2294145520672194 0.1712124245139879 0.8640567383949707 1.0 1.0 24 P43034,Q14674,Q14203,O75122,P42858 5 +Adherens junction organization 0.2516779491979047 0.1708057035579124 0.8643765441926674 1.0 1.0 14 P41240,Q13177,P18206,Q96AC1,P35241 5 +Regulation of nuclease activity 0.2663289919270751 0.1698218324929271 0.8651502564743199 1.0 1.0 11 P09429 1 +Pyrimidine ribonucleoside diphosphate metabolic process 0.3505847953216404 0.1695304310202751 0.8653794382792428 1.0 1.0 5 Q05682,P11172,P27708,Q02127 4 +Rrna methylation 0.266089569998914 0.1691222215319323 0.8657005064378434 1.0 1.0 11 Q9UI30,Q96P11 2 +Vesicle organization 0.2087140753609469 0.1680511853336525 0.8665430115508739 1.0 1.0 101 Q9UN37,O75351,Q8WUH2,Q15075,Q9NZZ3,P04083,Q86VS8,O95486,O95487,O95721,P53990,P78356,Q15437,Q8NEB9,P40818,O00203,Q92783,O60343,O14617,Q9HD42,O60763,Q9NR31,P43034,Q15436,Q9BXS5 25 +Regulation of growth 0.1915877677036805 0.1679074427840026 0.8666560947667485 1.0 1.0 132 P30153,P42771,O95251,P15311,Q13043,Q96J02,Q16539,Q96K76,O60271,Q9Y2J2,Q16555,Q96PU5,O43598,Q4G0X4,P53990,P16989,P46109,P49841,Q13177,Q04637,O75832,Q00535,P46821,Q9BSK2,Q7Z4V5,O95067,P43034,Q9P265,Q6IBS0,Q8N0X7 30 +Retina vasculature morphogenesis in camera type eye 0.4674262342974156 0.166948332779815 0.8674107027121656 1.0 1.0 2 O14786 1 +Retina vasculature development in camera type eye 0.4674262342974156 0.166948332779815 0.8674107027121656 1.0 1.0 2 O14786 1 +Regulation of neurotransmitter levels 0.2058148050448867 0.166267208872734 0.8679466703554459 1.0 1.0 33 Q99497,P49841,Q00535,Q4J6C6,P35080,Q15042,P0DP25,O95721 8 +Membrane disassembly 0.3229198208672261 0.1655039836847713 0.8685473145464337 1.0 1.0 6 P43034,Q14203 2 +Actin filament organization 0.2049145370088923 0.1653348005254036 0.8686804688682317 1.0 1.0 113 Q16658,O15144,P47755,P42345,O60610,P15311,O15357,P35080,P16949,Q16512,Q12792,O95429,P57737,Q96JJ3,P61160,Q15942,Q9Y281,Q96AC1,P07737,Q68EM7,P06753,Q9UQB8,O60504,O15145,P67936,O75116,Q13177,Q9BPX3,P23528,P60983,P12814,P35241,Q14195,P29966,Q14019,Q9NUQ9,Q8N8S7,Q13045,P58546,P49006,P60981,Q9UEY8,P62330,Q14247,Q6IBS0,O75122,Q9UHB6,O60879,Q7Z460,Q9Y5K6 50 +Golgi disassembly 0.348538011695907 0.1651218081986984 0.8688481081585093 1.0 1.0 5 Q08379,Q92538,Q99986,P06493 4 +Positive regulation of stress activated protein kinase signaling cascade 0.2498535293779178 0.1650509462202789 0.8689038826102453 1.0 1.0 14 P09429,P19525,Q13546,P98170 4 +Receptor signaling pathway via stat 0.239268898247383 0.1650163180519926 0.8689311381845168 1.0 1.0 17 P22059,O14964,P30153,P42224,Q9H490,Q6IA86,Q13043,Q00535 8 +Maintenance of dna repeat elements 0.3677287342882127 0.1647162513069159 0.8691673250114267 1.0 1.0 4 P20585,P43246,P52701 3 +Regulation of cell killing 0.2766802928567164 0.1639298887956238 0.8697863375217445 1.0 1.0 9 P46108,Q9NUQ9 2 +Positive regulation of macrophage differentiation 0.3672075793101583 0.163684220020967 0.8699797405911291 1.0 1.0 4 P06400,Q13546 2 +Regulation of macrophage differentiation 0.3672075793101583 0.163684220020967 0.8699797405911291 1.0 1.0 4 P06400,Q13546 2 +Signal transduction in response to dna damage 0.2016288763067615 0.1632083944391952 0.8703543570224652 1.0 1.0 53 Q16539,Q9UNS2,Q9NVH2,Q96RU2,Q13535,Q06124,Q9NWV8,P15927,O75832,P24941,Q9NZJ0,P14174,O60921 13 +Ribonucleoprotein complex disassembly 0.3668517977199568 0.1629821778864442 0.8705324670243624 1.0 1.0 4 Q14562,P33176,Q07866 3 +Dopaminergic neuron differentiation 0.4573871242865027 0.1626455981882159 0.870797482819206 1.0 1.0 3 P49841 1 +Receptor mediated endocytosis 0.1993981826609897 0.1624074941244441 0.8709849697286736 1.0 1.0 62 Q7Z6M1,P46934 2 +Cellular response to nitrosative stress 0.4570176952615752 0.1620246186908816 0.8712864671051228 1.0 1.0 3 P31689 1 +Cell cell recognition 0.2486947334214892 0.1614529629162123 0.8717366554023669 1.0 1.0 14 P17931,P26038,P17987,Q14157,P78371,P50991,P04075,P48643,P49368 9 +Regulation of dna dependent dna replication initiation 0.3659618802797329 0.1612350586501543 0.8719082695313394 1.0 1.0 4 O95251 1 +Lymphocyte costimulation 0.346198830409356 0.16017224137438 0.8727453952315338 1.0 1.0 5 P41240,P07947,P07948,Q06124 4 +Regulation of leukocyte mediated cytotoxicity 0.2833371360022069 0.1595635864576326 0.8732248651826817 1.0 1.0 8 P46108 1 +Response to acid chemical 0.2107941157345811 0.1595087563560784 0.8732680600680427 1.0 1.0 30 Q9UQB8,Q8NEB9 2 +Regulation of t cell mediated immunity 0.3457261990231191 0.1591837137302727 0.8735241348097875 1.0 1.0 5 P09429 1 +Metencephalon development 0.2136969015757378 0.1590194650609996 0.8736535380657671 1.0 1.0 29 Q02750,P48444,P46109,P12277,P27695,Q06124,O95487,Q9UKA9,P31939,P46108,Q00535 11 +Positive regulation of defense response to virus by host 0.3199936628736156 0.1586797407838208 0.8739212004386541 1.0 1.0 6 P07900,Q8TDB6 2 +Viral translation 0.2381388605415806 0.157592847016273 0.8747776403917786 1.0 1.0 16 O75821,O15371,Q14152,Q9Y262,P05455 5 +Cardiac neural crest cell differentiation involved in heart development 0.4612912649722587 0.1565642505697408 0.8755882789234224 1.0 1.0 2 P60953 1 +Cellular response to interferon alpha 0.4520748100525824 0.1538843106428659 0.8777009550400541 1.0 1.0 3 P10155,P12270 2 +Positive regulation of pattern recognition receptor signaling pathway 0.2605607547107104 0.1534221379029805 0.8780653880320171 1.0 1.0 11 P09429 1 +Dna strand elongation involved in dna replication 0.2502068654430465 0.1532365397345892 0.878211743394594 1.0 1.0 13 Q07864,P40938,P25205,P33991,P18858 5 +Renal system process 0.2499873142962795 0.1526082705894855 0.8787072024165481 1.0 1.0 13 Q9UNF1,P11274,Q9Y5X3,P17612,Q16512,Q0IIM8 6 +Regulation of gluconeogenesis 0.2664721427945125 0.1524934492641202 0.87879775674564 1.0 1.0 10 Q9BYT8,Q13043 2 +Positive regulation of mononuclear cell migration 0.2529059712456298 0.149793360398101 0.8809276478888088 1.0 1.0 12 P09429,O95747 2 +Response to lipid 0.1946782832469404 0.1495661160333239 0.8811069429021712 1.0 1.0 154 Q9GZZ9,O75874,P49321,O43251,O43823,Q16512,P09429,Q16539,Q9NZZ3,P04083,Q13126,Q53EL6,P06744,P49841,P40818,P04150,P46934,O95831,P17174,P46821,O95999,Q86X55,P07196,Q6IBS0,O95747,P0DP25 26 +Chromosome separation 0.2015547221097588 0.1485068499076815 0.8819427804538642 1.0 1.0 39 Q9H4L7,P30153,O43670,Q15645,P33981,Q14674,Q9Y6G9 7 +Positive regulation of metallopeptidase activity 0.4560327198364126 0.1480873899510484 0.8822738010802036 1.0 1.0 2 P40763 1 +Negative regulation of ire1 mediated unfolded protein response 0.4560327198364119 0.1480873899510475 0.8822738010802043 1.0 1.0 2 O94874 1 +Fatty acid homeostasis 0.3152218470574278 0.1479123250016164 0.8824119612567778 1.0 1.0 6 Q13131,P17174 2 +Positive regulation of aspartic type peptidase activity 0.4482758620689497 0.1478404747837465 0.8824686660405543 1.0 1.0 3 O75116,Q13492 2 +Aortic valve morphogenesis 0.3586740303694481 0.1474064435851662 0.8828112198367226 1.0 1.0 4 Q13464,O75116 2 +Regulation of cellular response to hypoxia 0.3392344771815954 0.1459994294895108 0.8839218388029784 1.0 1.0 5 O94966 1 +Hormone mediated signaling pathway 0.1984266936698379 0.1458888824208665 0.884009108229459 1.0 1.0 45 Q9GZZ9,P42785,Q86X55,P04150,P46934 5 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.3577901198479984 0.1457873542248297 0.884089259106535 1.0 1.0 4 P04439,O14920,Q03518 3 +Regulation of hematopoietic progenitor cell differentiation 0.2434043408374529 0.1455949420723858 0.8842411610781409 1.0 1.0 14 Q00534,Q9Y5A9,Q9HCE5,Q96PZ0,Q96J02,P19525 6 +B cell proliferation 0.2700287505548818 0.1453129510792917 0.8844637897755856 1.0 1.0 9 Q16512,P17812 2 +Regulation of p38mapk cascade 0.3388697718663098 0.1452805311710127 0.884489385511275 1.0 1.0 5 P15311 1 +Regulation of dna repair 0.1984777213025891 0.1449213138761975 0.8847729980444012 1.0 1.0 53 P09429,Q96T76,Q99504,Q96FW1,Q7Z4V5,Q9NYB0,Q9NY27,O95251,Q9NWV8,P15927,Q9UNS1,O96028,P23396,Q9NQ88 14 +Toll like receptor 9 signaling pathway 0.4463718407487964 0.1448806707335364 0.8848050879215905 1.0 1.0 3 P09429 1 +Nucleotide excision repair dna incision 0.3572563648461269 0.1448157466112513 0.8848563492883552 1.0 1.0 4 P18074 1 +Myeloid leukocyte differentiation 0.2010678030438196 0.1443996855636762 0.8851848650912495 1.0 1.0 34 O00625,Q16539,Q00534,O00203,Q04760,Q13546 6 +Aminoacyl trna metabolism involved in translational fidelity 0.2629575402635405 0.1429424753524738 0.8863356125145501 1.0 1.0 10 Q9P2J5,Q5ST30,Q9BTE6,P26640,P41252,P49588,Q5JTZ9,Q15031,Q9NSE4 9 +Negative regulation of notch signaling pathway 0.3561540717267153 0.1428237267070912 0.8864293979800562 1.0 1.0 4 Q86U44,Q9Y5A9 2 +Sodium ion homeostasis 0.2942361387506894 0.1413907115945488 0.8875612916311031 1.0 1.0 7 Q96PU5 1 +Scarna localization to cajal body 0.3548669979538169 0.1405225194634601 0.8882471610596325 1.0 1.0 4 P17987,P50991,P78371 3 +Diadenosine polyphosphate metabolic process 0.4507741747005684 0.1399990284384317 0.8886607580224171 1.0 1.0 2 P41250 1 +Sensory perception of light stimulus 0.2291959124733721 0.1399370279322286 0.8887097450574688 1.0 1.0 19 Q9H6K4,O43924,Q00169,Q15555 4 +Positive regulation of histone ubiquitination 0.3359649122807007 0.1396374424258989 0.8889464556536633 1.0 1.0 5 Q5VTR2,O75150,P50750,Q6PD62 4 +Histone ubiquitination 0.2260623245695942 0.1395936408330552 0.8889810653048971 1.0 1.0 21 Q99497,Q9HC52,Q96FW1,O75150,P63208,Q9NW82,Q7Z6Z7,Q8TDB6 8 +L serine biosynthetic process 0.4504820333041269 0.1395610016957898 0.8890068551246524 1.0 1.0 2 Q9Y617 1 +Regulation of protein maturation 0.2486919796905246 0.1386686715212298 0.8897119753783456 1.0 1.0 12 P17612,P20810,P98170 3 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.275139212023335 0.1380783444931209 0.8901785004147837 1.0 1.0 8 O95999 1 +Regulation of binding 0.2015512754946893 0.1369581386019624 0.8910638837881608 1.0 1.0 113 Q15691,Q99497,P62942,O60869,Q13043,Q9H1E3,P62826,Q13526,P46108,P16949,Q86YR5,Q9GZU8,P09429,P19474,P48729,Q96D46,Q14012,P17612,P30626,P15531,Q96AQ6,P08238,P48681,P49841,Q04637,Q8TDB6,Q00535,O15371,O14981,Q86X55,O14965,P0DP25 32 +Terminal button organization 0.448437043529078 0.1365280437044374 0.8914038564403237 1.0 1.0 2 Q96QK1 1 +Regulation of axon guidance 0.3522361882490578 0.1359016672079863 0.891899017464101 1.0 1.0 4 O14786,Q9BVA1,O75592 3 +Positive regulation of establishment of protein localization 0.2046533840555087 0.1350591658571258 0.892565095218659 1.0 1.0 99 O94766,Q9UBE0,P08237,Q12955,P15311,P62826,Q16539,Q9Y282,P78371,Q9H6U6,O95486,Q14012,P17612,Q92688,P30626,P08238,P31751,P49841,O95817,O14737,P68036,Q13263,Q9UHD1,Q7Z6Z7,P62258,Q00535,Q9NR31,Q9Y3D6,P19784,P62330,Q9C0E2,Q9Y4C2,Q9Y5K6,P06493 34 +Hematopoietic stem cell proliferation 0.3089176486682397 0.1343776209927429 0.8931039769833651 1.0 1.0 6 O95251,Q9Y5A9 2 +Purine nucleotide catabolic process 0.2593915353693166 0.1336031902016936 0.8937163613924572 1.0 1.0 10 O43598,P00491,Q9Y3Z3,Q9BY32 4 +Plasma membrane tubulation 0.3326471205916228 0.1333724282304365 0.8938988496628943 1.0 1.0 5 Q9UNF0 1 +Biological adhesion 0.2102631999567657 0.1326295538856955 0.8944863582748652 1.0 1.0 186 P30153,P42771,Q12955,Q06124,P15311,Q9UEE9,Q13043,Q96J02,Q15417,P46108,P51617,O95429,P09429,Q16539,Q00534,Q96JJ3,Q9H4A3,P04083,Q9H6U6,Q96AC1,Q9P258,Q9UQB8,P23396,Q13740,O60504,Q13630,Q96AQ6,P46109,P49841,P04792,O00203,Q9NUQ9,P22392,O14617,Q00535,P00491,O95999,Q9Y223,Q96HC4,Q9UIW2,P51452,O75122,Q7Z460,Q9UNN5 44 +Golgi vesicle transport 0.1858969156091559 0.1321397397521559 0.8948737637136284 1.0 1.0 142 Q9UJY5,O43617,Q9UP83,Q9UID3,O15260,Q12955,P24390,P83436,Q9Y296,Q13596,Q9Y6Y8,Q8TD16,P42858,Q15437,P61923,Q8IUR0,Q4J6C6,O14617,Q9NR31,Q96RL7,Q15436,O60749 22 +Actin polymerization dependent cell motility 0.3494077166911951 0.1310576309347221 0.8957297176117947 1.0 1.0 4 Q8N8S7,O15144 2 +Regulation of bicellular tight junction assembly 0.2896430661205377 0.1308767980831712 0.8958727692359063 1.0 1.0 7 Q07157,O75116,O14920,P17252,Q13464,P17612 6 +Membrane protein ectodomain proteolysis 0.25190392501465 0.1306098670027131 0.8960839368577447 1.0 1.0 11 Q8TCT8,Q9Y5X1,O43847,Q8TCT9,Q13464,Q9NZ08,P35579,Q9UKS6,P38159,Q92542 10 +Neuron cellular homeostasis 0.2893371209558197 0.1301932030326582 0.8964135720054536 1.0 1.0 7 P78559,Q14203 2 +Regulation of t cell mediated cytotoxicity 0.4363916285936319 0.1301200515290807 0.8964714461629668 1.0 1.0 3 Q9NUQ9 1 +Positive regulation of t cell mediated cytotoxicity 0.4363916285936319 0.1301200515290807 0.8964714461629668 1.0 1.0 3 Q9NUQ9 1 +Positive regulation of nuclease activity 0.348763791478289 0.1299727743020112 0.8965879669073871 1.0 1.0 4 P23396,P12004 2 +Response to virus 0.202774630885571 0.1293442170394602 0.8970852851270255 1.0 1.0 88 Q9NVU0,Q16539,P19474,Q13325,Q00534,P26641,Q9UHR5,P25787,Q9HCE1,Q9Y3Z3,Q9NUD5,P04792,Q13283,Q13309,Q96J02,P63241,P16949,Q8TDB6 18 +Positive regulation of mrna processing 0.2210724772532525 0.1291289261379252 0.8972556338663777 1.0 1.0 22 P98179 1 +Tor signaling 0.2086615050248562 0.1290106585095178 0.897349215040758 1.0 1.0 28 Q9H4A6,Q96A49,Q9P2J5,Q6PKG0,Q9Y243,Q96Q15,P42345,Q9NWS0,P62753,O15379,P10398,Q13131,Q9Y4R8,Q96B36,O75663 15 +Stem cell proliferation 0.2438213538139022 0.1264782734993767 0.8993533461616141 1.0 1.0 12 Q96AC1,O95251,Q9Y5A9,P19525 4 +Positive regulation of developmental process 0.2205464996946234 0.1255803792063174 0.9000640951067524 1.0 1.0 209 Q9H2J4,Q8N2A8,Q9UPY3,P46108,P09429,Q16539,P55209,P04083,Q96AC1,O96028,Q14012,Q9UQB8,Q96PU5,P53990,P16989,P46109,O43379,P04792,O00203,Q9GZP4,P22392,O14617,P46821,Q9UIW2,Q86X55,P07196,O75122 27 +Attachment of spindle microtubules to kinetochore 0.2244951554686128 0.125364934791867 0.9002346470478693 1.0 1.0 19 Q9HC35,Q15018,Q9HBM1,O43670 4 +Regulation of ras protein signal transduction 0.1961399719426928 0.1252565807081961 0.9003204249713046 1.0 1.0 32 P46108,P16949,Q5VZ89,Q15555 4 +Regulation of ligase activity 0.4301578024546987 0.1215372249016642 0.9032655320175786 1.0 1.0 3 Q13155,P48507 2 +Positive regulation of ligase activity 0.4301578024546987 0.1215372249016642 0.9032655320175786 1.0 1.0 3 Q13155,P48507 2 +Receptor internalization 0.2088846497837512 0.1213370649530882 0.9034240633009754 1.0 1.0 27 Q13614,P46934 2 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.2008225519557466 0.120065017473324 0.9044316438905796 1.0 1.0 30 P48729,P49841,O75832,P54725,Q15370 5 +Regulation of rho protein signal transduction 0.2408438324055047 0.1193789191848582 0.9049751619034034 1.0 1.0 12 P52565,O14786,P49407,P05556,P11274,P41440,Q13618,Q12802,Q92974,P16949,P63000 11 +Centriole centriole cohesion 0.3420947212464355 0.1191267347230727 0.9051749503095674 1.0 1.0 4 Q14203 1 +Protein localization to condensed chromosome 0.2471573482858757 0.1190256948830238 0.9052549989111078 1.0 1.0 11 Q96DY7 1 +Inner ear auditory receptor cell differentiation 0.2671720366365357 0.1188177844447738 0.905419718547804 1.0 1.0 8 Q9Y6M7,O95487 2 +Regulation of notch signaling pathway 0.2839927200201655 0.1185896734779043 0.9056004469863196 1.0 1.0 7 Q86U44,Q9Y5A9,Q96TA1 3 +Regulation of lymphocyte mediated immunity 0.2190114668766247 0.1177624700443174 0.9062558671373016 1.0 1.0 21 P09429,P46108,O96028 3 +Cellular response to mineralocorticoid stimulus 0.4272698795150715 0.117725230648173 0.9062853746257602 1.0 1.0 3 O95831 1 +Trophectodermal cell differentiation 0.3236842105263179 0.1174074114429974 0.9065372112113296 1.0 1.0 5 Q13895,Q6PD62,A5YKK6,Q13618 4 +Nucleoside diphosphate biosynthetic process 0.26638834983192 0.1170100304407193 0.90685210494317 1.0 1.0 8 P23919 1 +Protein processing 0.1927133141094 0.1164947760094824 0.9072604260512708 1.0 1.0 49 Q15392,Q96E52 2 +Bone remodeling 0.2584275944350216 0.1156765938420161 0.9079088571086094 1.0 1.0 9 O14773,Q92791,Q9UBB6 3 +Inositol phosphate mediated signaling 0.2995146095385621 0.1156562829373486 0.9079249548214516 1.0 1.0 6 P49841,Q9UHD1 2 +Calcineurin mediated signaling 0.2995146095385621 0.1156562829373486 0.9079249548214516 1.0 1.0 6 P49841,Q9UHD1 2 +Regulation of calcineurin mediated signaling 0.2995146095385621 0.1156562829373486 0.9079249548214516 1.0 1.0 6 P49841,Q9UHD1 2 +Positive regulation of receptor catabolic process 0.4250388555651955 0.1148509060578834 0.9085632987852474 1.0 1.0 3 Q96J02 1 +Myotube cell development 0.4248977206311981 0.1146711361407324 0.9087057929992284 1.0 1.0 3 Q9H7B4,Q96TA1 2 +Nuclear migration 0.2319706257838653 0.1145362876266382 0.9088126822941314 1.0 1.0 14 Q9Y266,Q86VS8,Q14203 3 +Response to chemokine 0.2820205571048019 0.1144692950397905 0.9088657853869522 1.0 1.0 7 O95747 1 +Negative regulation of response to biotic stimulus 0.2109280990925672 0.1143254166806781 0.9089798349917086 1.0 1.0 25 P19474,P39019,Q9Y3Z3,Q7Z739,Q96J02,P46108 6 +Regulation of immune effector process 0.1918622390439804 0.1135008868382823 0.9096334600307284 1.0 1.0 48 P09429,P06744,P04083,O96028,Q9NUQ9,P46108,Q16512 7 +Negative regulation of cell growth 0.1959083857311541 0.112663552602734 0.9102972980286744 1.0 1.0 31 P30153,P42771,O60271,Q9P265,Q8N0X7 5 +Positive regulation of vacuole organization 0.3196296136648842 0.1106435618681951 0.9118990021616852 1.0 1.0 5 P78356 1 +Dna conformation change 0.1824124773608726 0.1101260408725116 0.9123094161302864 1.0 1.0 140 Q9Y248,P49736,P40938,Q15047,P24941,Q99733,P49321,O43823,P09429,Q01105,Q9H4L7,P55209,P04083,Q8N3C0,O14929,P13010,O14646,Q92688,P33991,P46063,Q12873,Q86WJ1,Q9BPX3,Q04837,Q9HCK8,Q8WXX5,O95831,Q9HD42,O15347,Q9BRT9,Q9UER7,Q9UPP1,P41227,Q96SB4,P42695,Q9BXS6,Q13283,P38935,P25205,P13984,Q9Y620,P06493 42 +Muscle tissue development 0.1919144307138542 0.1101025389759671 0.9123280545903424 1.0 1.0 57 Q9BYT8,Q16539,P62942,P16989,Q16527,Q96HC4,O94966,O95747 8 +Regulation of peroxisome proliferator activated receptor signaling pathway 0.4274028629856936 0.1086442095979935 0.913484694082487 1.0 1.0 2 Q96EB6 1 +Gastrulation 0.1973421556691906 0.1077179126183337 0.9142194599762836 1.0 1.0 30 P06744,Q92541,Q9H4A3,O95747,P62753,O75122,P17612,O60701,Q7Z460 9 +Nucleus localization 0.2252529421077393 0.1069446640039537 0.9148328795980024 1.0 1.0 15 P43034,Q9Y266,Q86VS8,Q14203 4 +Synaptic vesicle uncoating 0.4259421560035153 0.1069266895599915 0.9148471393638844 1.0 1.0 2 Q99961 1 +Positive regulation of glial cell differentiation 0.2945318193520842 0.1064466924860399 0.9152279482434352 1.0 1.0 6 Q9UPY3 1 +Entry of bacterium into host cell 0.3335282081262755 0.106229675615024 0.915400126417756 1.0 1.0 4 Q9BTY2,Q9UPT5,Q96KP1 3 +Nuclear transcribed mrna catabolic process nonsense mediated decay 0.218990442395332 0.1060976664896682 0.9155048625683112 1.0 1.0 18 P62495,Q96Q15,P60228,P15170,Q9HAU5,A2RRP1,Q9BZI7,Q9NPI6,Q15477 9 +Leukocyte migration 0.1902841692536384 0.1060124348776392 0.9155724861800671 1.0 1.0 48 P09429,P46109,O95747,P04083,P46108,P30046 6 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.316666666666667 0.1058801496915092 0.9156774437771468 1.0 1.0 5 Q99729,Q9Y5S9,P11940,A2RRP1 4 +Response to fluid shear stress 0.4247735904177718 0.1055725769687696 0.9159214835382858 1.0 1.0 2 O15379 1 +Cellular response to fluid shear stress 0.4247735904177718 0.1055725769687696 0.9159214835382858 1.0 1.0 2 O15379 1 +Cellular response to water stimulus 0.4247735904177664 0.1055725769687635 0.9159214835382908 1.0 1.0 2 Q96FS4 1 +Regulation of sister chromatid cohesion 0.241206812497379 0.1054285197957995 0.9160357866413602 1.0 1.0 11 P41227,Q14674 2 +Monosaccharide catabolic process 0.2282434438239462 0.1053649557787515 0.9160862224772296 1.0 1.0 14 P85037,Q9UKK9 2 +Negative regulation of epithelial cell differentiation 0.3326931941122104 0.1050341639583071 0.9163486997256008 1.0 1.0 4 O95747 1 +Regulation of calcium ion transport 0.1913808396835788 0.1035804801846594 0.9175022788828656 1.0 1.0 37 P0DP25,P62942,P28161 3 +Maintenance of protein location in cell 0.2123681092947703 0.1035217324687618 0.9175489021403992 1.0 1.0 22 P24390,Q96RL7,Q12955,Q6IBS0,Q00535 5 +10 formyltetrahydrofolate metabolic process 0.4156012962638131 0.1033641889463305 0.9176739329490652 1.0 1.0 3 Q9NRN7 1 +Regulation of neural precursor cell proliferation 0.2234764708343921 0.102465875607742 0.9183868975698604 1.0 1.0 15 P55209,Q8NEM2,Q9UKA9,O43379 4 +Regulation of extracellular matrix disassembly 0.3308616879328167 0.1024499475568961 0.9183995397846556 1.0 1.0 4 O75122,Q7Z460 2 +Regulation of dna methylation dependent heterochromatin assembly 0.2758923346986555 0.1022206512971594 0.918581536250146 1.0 1.0 7 Q6VMQ6,O60341,Q9UK61,Q15047,Q13263,P26358 6 +Ribosomal large subunit assembly 0.2115780193946528 0.1013633161741377 0.919262055899984 1.0 1.0 22 Q9NZM5,P62913,Q9NU22,P27635,Q9NYY8,P46777,Q9UKD2,Q02878,Q8TDN6,P63173,Q7L2E3,Q14137,Q9H7B2,P39023,Q9NQ55,P83731,Q9NUL7,P62750,P46087,Q9NVX2,P05388 21 +Positive regulation of immunoglobulin production 0.2297394487130228 0.1012607739474007 0.9193434539456412 1.0 1.0 13 O96028 1 +Positive regulation of osteoblast differentiation 0.3296001843719748 0.1007002469709376 0.919788415317367 1.0 1.0 4 Q96AC1 1 +Glial cell differentiation 0.1888129547665853 0.1000453903828094 0.9203082898715635 1.0 1.0 45 P18074,P41240,P49770,Q00534,Q02750,Q14232,P42345,Q9HCE5,Q9NR50,P31751,P08670,Q00535,Q06124,Q9UPY3,Q13144,P06493,Q96P11,Q92542 18 +Regulation of genetic imprinting 0.4198071866783632 0.1000129169920854 0.9203340705867372 1.0 1.0 2 Q13263 1 +Genomic imprinting 0.4198071866783632 0.1000129169920854 0.9203340705867372 1.0 1.0 2 Q13263 1 +Positive regulation of gene expression 0.2276902045926573 0.0998897060897271 0.9204318888259572 1.0 1.0 232 Q96FZ2,Q99497,P34913,Q9HCE5,Q9H2J4,P51114,Q86W50,P36507,Q12955,Q06124,P15311,P63241,Q96P11,P67809,O75794,P30046,P09429,Q16539,Q00534,Q02750,Q13243,P04083,Q9NUD5,Q14011,O96028,P14174,P23396,P06744,P16989,P49841,P04792,O14737,Q99439,Q9NUQ9,Q13546,P98179,O60684,P30041,O15371,P62081,P00491,O95999,Q9UPP1,Q96SZ6,Q7Z739,Q13144,Q13283,O95747,Q96AE4 49 +Histone h2a monoubiquitination 0.3288512130955819 0.099673060892635 0.920603888307434 1.0 1.0 4 Q16531,Q13620,P63208 3 +Homotypic cell cell adhesion 0.2174615019302909 0.0991974952643559 0.9209814635408832 1.0 1.0 17 P04792 1 +Regulation of histone ubiquitination 0.2443825132111718 0.0981990745193504 0.9217742173403338 1.0 1.0 10 O75150,Q99497,Q9NW82,Q96FW1 4 +Regulation of response to biotic stimulus 0.1896781321493117 0.0972017405536084 0.9225661858306078 1.0 1.0 71 P09429,P19474,P08238,Q9Y5A9,P98170,P39019,Q16543,Q9Y3Z3,Q13177,Q9NUD5,P14174,Q7Z739,Q06124,Q96J02,P46108,Q16512,Q9NQ88,Q8TDB6 18 +Positive regulation of cell death 0.1902457460453763 0.0953181614204931 0.9240621176046832 1.0 1.0 124 Q99497,P30153,O00716,P42771,Q13043,Q96E52,P63241,P09429,Q6SZW1,P30154,P04083,P31689,Q53EL6,P23396,Q05639,P42858,P49841,Q13177,O14737,Q04637,Q13546,O95831,Q00535,Q92879,Q15257,Q2TAL8,P49427,P62081,O95999,Q13144,Q9NQ88,Q9UNN5 32 +Forebrain morphogenesis 0.4148407829389457 0.0947643533429472 0.9245020013209152 1.0 1.0 2 P21359 1 +Mrna methylation 0.2425973991637214 0.0944078210231934 0.9247852032779992 1.0 1.0 10 Q9UJA5,Q9HCE5 2 +Positive regulation of ubiquitin protein ligase activity 0.324386085984525 0.0937280304995045 0.9253252031692958 1.0 1.0 4 Q16763 1 +Inositol metabolic process 0.4058627144809014 0.0926262410253951 0.9262004960398268 1.0 1.0 3 Q13572 1 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.3229286060562405 0.0918532847295916 0.9268146078693378 1.0 1.0 4 Q16543 1 +Aspartate family amino acid metabolic process 0.2060141551195776 0.0912608067504209 0.9272853596701314 1.0 1.0 23 P17174,Q13126,Q9BV20 3 +Cell growth 0.1965468985744693 0.0904328960681793 0.9279432164979208 1.0 1.0 110 P30153,P42771,O95251,Q96J02,Q96K76,O60271,Q9Y2J2,Q16555,Q13740,Q96PU5,O43598,P08238,P53990,P46109,P49841,Q04637,O75832,Q00535,P46821,Q9BSK2,Q7Z4V5,Q96HC4,P43034,Q9UIW2,Q9P265,Q6IBS0,O14965,Q8N0X7 28 +Positive regulation of synaptic transmission 0.2116803009901466 0.0902235583150685 0.9281095638429842 1.0 1.0 19 P49841,P21359,P27695,Q9BPZ3,Q00535,Q15042,O95793,Q92542,Q06787 9 +Negative regulation of protein metabolic process 0.2500130558951092 0.0897874413364267 0.9284561282400554 1.0 1.0 306 P00374,P30153,Q9H2J4,O43768,P30086,Q969T7,P61201,P67809,P19474,Q96K76,Q5TAX3,P31689,Q53EL6,O60271,P14174,P30740,Q16850,Q9C0C9,P04792,Q9UHD1,Q00535,Q15392,P61758,P0DP25,Q04323,Q9NQP4,Q99497,P62942,P98170,Q9HCE5,Q96C86,Q86W50,O60493,Q13526,Q01105,Q9UHV9,Q9NYB0,Q9BPZ3,Q9NY27,Q14011,Q96KB5,P78318,P08238,O15212,P20810,Q96FW1,Q13177,Q13107,Q04637,Q9Y6M1,Q8TDB6,Q92879,Q15257,P62081,Q9HCE1,Q96SZ6,P51452,P51114,P42771,Q96B36,Q16512,P62841,Q9UNH7,P78559,P23396,P04080,P06744,P46109,Q6DKJ4,Q9Y2L1,O94966,O60678,P31946,Q99471,O95373,P49841,Q7Z739,Q9NPI6 78 +Antigen processing and presentation 0.2022907261262159 0.0894042213439804 0.9287606687609612 1.0 1.0 25 O00203,Q6P179 2 +Positive regulation of nitric oxide metabolic process 0.3207826001639304 0.0891512933648568 0.9289616734359498 1.0 1.0 4 P08238,P07900 2 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.3206664717918707 0.0890070534572407 0.9290763045232444 1.0 1.0 4 Q04637,P40763,P26196 3 +Srp dependent cotranslational protein targeting to membrane 0.2462412544704986 0.0884635513316632 0.9295082525513338 1.0 1.0 9 Q9UHB9,O76094,P49458,Q9UGP8 4 +Renal water homeostasis 0.3197895352236141 0.0879243553065616 0.9299367988311144 1.0 1.0 4 P17612,P15121,P17252 3 +Positive regulation of immune system process 0.1951307796419776 0.0877144323807738 0.930103648457481 1.0 1.0 113 Q96FZ2,Q99497,Q14232,Q06124,P15311,Q96J02,Q16512,P09429,Q9H4A3,Q9NR50,P04083,Q9NUD5,O96028,P14174,P23396,P06744,P46109,P39019,O00203,Q9NUQ9,O14617,Q13546,P49770,P00491,O95999,Q13144,P51452,O95747 28 +Translational termination 0.2680123364217054 0.0876979839904145 0.930116721994076 1.0 1.0 7 P62495,P63241,P61221 3 +Secretion by tissue 0.4006744226229243 0.0873546088099448 0.9303896483188638 1.0 1.0 3 Q9H4A3 1 +Regulation of neuronal synaptic plasticity 0.2455993135145245 0.0871411709553911 0.9305593001456682 1.0 1.0 9 Q15042,Q9UBB6 2 +Lactate metabolic process 0.2829185440594506 0.0868765252409363 0.9307696591003564 1.0 1.0 6 Q9NQ88,Q99497,P00338 3 +Epithelial cell differentiation involved in kidney development 0.2820029746378051 0.0854451673607371 0.9319074860709308 1.0 1.0 6 P42224,O95747 2 +Cell differentiation involved in kidney development 0.2820029746378051 0.0854451673607371 0.9319074860709308 1.0 1.0 6 P42224,O95747 2 +Negative regulation of tubulin deacetylation 0.4052001168565673 0.0854361025817486 0.9319146923667224 1.0 1.0 2 Q13131 1 +Dna templated transcription initiation 0.1860651273619976 0.0846555548752987 0.9325352311380384 1.0 1.0 42 P09429,O60244,P62333,Q14241,O00716,Q00059,Q86VP6,P29083,Q15370 9 +Regulation of translation at synapse modulating synaptic transmission 0.3165741011400147 0.0840524505394168 0.9330147297709156 1.0 1.0 4 P06730,Q7L576,P35268 3 +Defense response 0.2200818778196684 0.0837409103472569 0.9332624296069518 1.0 1.0 218 Q9NVU0,Q13325,Q99497,P17931,P98170,P42345,Q06124,P28070,Q96J02,P81605,P46108,P51617,Q16512,O43823,P30046,P09429,Q16539,P19474,Q6SZW1,P04083,Q9Y3Z3,Q16543,Q9NUD5,P60900,Q53EL6,Q9UN86,Q9UNH7,P07437,P14174,Q96KB5,Q13137,Q96C90,Q96AQ6,P08238,O95373,P39019,P42785,Q13177,O00203,Q04637,Q13546,Q8TDB6,Q92879,O60684,Q01804,Q9Y5A9,O15347,Q9BXW9,O95999,Q8IV08,Q9HCE1,Q9UII4,Q96SB4,Q7Z739,Q13283,Q13309,P25786 57 +Head morphogenesis 0.3010187600755017 0.0831961903024656 0.9336955419378368 1.0 1.0 5 Q06124 1 +Response to dopamine 0.2152492668621713 0.08318596838146 0.9337036696770225 1.0 1.0 15 P32121,P50570,P49841,P09471,P21333,P29992,P28482,O14745,O14744,Q92542,Q92769,P49840,P08754,Q96QK1 14 +Nadh regeneration 0.2652991141664402 0.0830142382664667 0.933840218192765 1.0 1.0 7 P85037,P08237 2 +Negative regulation of growth 0.1849688209506634 0.0825576050290009 0.9342033124306824 1.0 1.0 34 P30153,P42771,O60271,Q13043,Q9P265,Q8N0X7 6 +Nuclear membrane organization 0.2050838719610765 0.0809147231490409 0.9355097709799812 1.0 1.0 21 Q9NZZ3,Q9HD42 2 +Regulation of vitamin d receptor signaling pathway 0.3930450029222586 0.0801517009001908 0.9361166036068064 1.0 1.0 3 O15164,Q15648 2 +Vitamin d receptor signaling pathway 0.3930450029222586 0.0801517009001908 0.9361166036068064 1.0 1.0 3 O15164,Q15648 2 +Negative regulation of plasma membrane bounded cell projection assembly 0.263395621792536 0.0798242047737816 0.9363770731229706 1.0 1.0 7 P35080,P27816,P50570 3 +Genitalia development 0.2976538345515368 0.0788502727925486 0.9371517165862312 1.0 1.0 5 Q15392 1 +Positive regulation of immune effector process 0.1842940069791603 0.0785083142140534 0.9374237168513826 1.0 1.0 36 P06744,Q96FZ2,O95999,P04083,O96028,Q9NUQ9,P14174 7 +Negative regulation of signal transduction in absence of ligand 0.2622284084595588 0.0779069950252133 0.9379020351002474 1.0 1.0 7 Q13546 1 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.2472660243646083 0.0777098795953519 0.9380588350934888 1.0 1.0 8 P14174,Q96K76 2 +Positive regulation of mitotic cell cycle phase transition 0.1840323208505113 0.0763098329013008 0.9391726031323128 1.0 1.0 39 P31350,O75351,P04083,Q96DY7,Q9P258,Q14674,Q9NZJ0,Q6UVJ0 8 +Positive regulation of dna methylation dependent heterochromatin assembly 0.2758116408306417 0.0761867233339114 0.939270545233259 1.0 1.0 6 Q6VMQ6,Q9UK61,Q15047,Q13263,P26358 5 +Steroid hormone mediated signaling pathway 0.1838409996988075 0.0756235892041422 0.9397185687298386 1.0 1.0 40 Q9GZZ9,P46934,Q86X55,P04150 4 +Spermidine metabolic process 0.3872494329620349 0.0751038802001715 0.9401320605933284 1.0 1.0 3 Q6QHF9 1 +Embryonic hemopoiesis 0.308259402212816 0.0747415361088741 0.9404203590422722 1.0 1.0 4 Q13043 1 +Regulation of glial cell apoptotic process 0.3081426186274882 0.0746178341370873 0.9405187840916372 1.0 1.0 4 Q00535 1 +Positive regulation of histone phosphorylation 0.3920537540169457 0.074452114592991 0.9406506423810927 1.0 1.0 2 Q06787 1 +Stem cell division 0.3078047354574678 0.0742610219637342 0.9408026913262516 1.0 1.0 4 P43034,Q01085,Q13618 3 +Late nucleophagy 0.3911773298276373 0.0737875674762694 0.9411794197734012 1.0 1.0 2 O95352 1 +Cellular response to uv 0.1907313755522468 0.0734897472314495 0.9414164025383966 1.0 1.0 28 Q13535,P46934 2 +Positive regulation of lamellipodium assembly 0.2157920802635228 0.073413053032538 0.9414774308062976 1.0 1.0 13 O15144,Q16658,P50570,P42345,Q6IBS0 5 +Regulation of cell population proliferation 0.2298225395274813 0.0733600204657335 0.941519630883404 1.0 1.0 245 P98170,Q9H2J4,P33981,P42771,Q9UEE9,Q9UPY3,Q96J02,Q9UBL3,O43251,Q16512,O75794,P09429,Q16539,Q00534,P55209,Q02750,P04083,Q96AC1,Q53EL6,Q96G23,Q9UNS1,P23396,P15531,Q96AQ6,O43815,P46109,P35244,O43379,O14737,Q99439,P22392,P43490,P49006,Q15392,Q96DY7,Q86X55,O95747 37 +White fat cell differentiation 0.3848626534190513 0.0731284306217384 0.9417039178566956 1.0 1.0 3 Q13363,Q96EB6 2 +Positive regulation of mitochondrial membrane potential 0.3066354866997891 0.0730387088018938 0.9417753145842688 1.0 1.0 4 P55072,Q8IWA4,P31751 3 +Dopamine receptor signaling pathway 0.2240773286467518 0.0719596358101438 0.9426340304935368 1.0 1.0 11 P49841,P09471,P21333,P29992,O14745,O14744,P49840,Q96QK1,P08754,Q92542 10 +Metaphase anaphase transition of cell cycle 0.1830822501823803 0.0712166069718251 0.9432253645234728 1.0 1.0 31 O43670,Q15645,P33981,Q14674,Q9Y6G9 5 +Mammary gland morphogenesis 0.2912280701754418 0.0710583556025361 0.9433513117635076 1.0 1.0 5 Q14160,P07384,Q15648,Q99623 4 +Protein localization to chromosome centromeric region 0.213893372929642 0.0700823051231808 0.9441281505352188 1.0 1.0 13 Q96DY7 1 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.181053275665786 0.0700160323243504 0.9441808990039482 1.0 1.0 46 P48729,P62191,P62195,P62333,P49841,O75150,Q92995,P43686,O75832,P54725,O14965,P17980,Q15370,Q9Y5A7 14 +Positive regulation of cell projection organization 0.1847570157620419 0.06935485288153 0.9447071645225144 1.0 1.0 71 Q16658,O15144,Q32P28,P42345,O60493,P78344,Q12792,Q06787,Q02750,P50570,P27695,Q9H6U6,Q9UHD8,P07737,Q14012,Q9UQB8,P42858,P53990,P49841,Q14195,P46821,Q15555,Q9NUL3,P43034,Q9UIW2,P07196,Q9NZQ3,Q6IBS0,P11233,Q9UL25,Q9H4M9 31 +Megakaryocyte development 0.3799538606122034 0.0692504066571759 0.9447903006670116 1.0 1.0 3 Q06124 1 +Activation of protein kinase b activity 0.3793502619819264 0.068790446914044 0.9451564223332756 1.0 1.0 3 Q99497 1 +Positive regulation of protein modification process 0.2120409838367829 0.0686089876050282 0.9453008646529752 1.0 1.0 204 Q9NVI1,Q96A49,Q8IV63,Q99497,P62942,Q92541,P98170,P51114,Q9UBE0,P36507,P33981,O95251,Q06124,P15880,Q9GZS3,Q13043,P35080,Q13526,Q93062,P51617,Q16512,O43823,O95429,Q02750,Q9H4A3,Q9NYB0,Q96AC1,Q14738,Q14012,P14174,Q9Y4R8,Q15435,P23396,Q86Y37,P08238,P46109,P31751,Q96M27,Q13177,Q04637,P68036,O75832,Q9UHD1,Q7Z6Z7,Q15042,Q13546,Q96GG9,Q00535,O95999,P10398,Q13309,Q9P265,P0DP25,Q9UBT2,Q9UHR5 55 +Positive regulation of centriole replication 0.3788669996729668 0.068424819805632 0.94544746478033 1.0 1.0 3 O75351 1 +Regulation of intracellular transport 0.1866970126570235 0.0681343211411237 0.9456787095071164 1.0 1.0 124 Q99497,P26038,O14980,O94766,Q9UBE0,P36507,O60493,Q12955,Q06124,P15311,P62826,O95429,Q16539,Q02750,Q9Y282,P27695,Q9H6U6,O95487,Q14012,P17612,Q92688,P08238,P31751,O75165,P49841,Q8IWJ2,O95817,O14737,P68036,P35241,Q13263,Q9UHD1,Q7Z6Z7,P62258,P46934,Q00535,Q13614,P46821,Q9UMY4,Q9NR31,Q9Y3D6,P19784,Q9C0E2,Q9UL25,Q9Y4C2,P06493 46 +Regulation of golgi organization 0.2555762918091952 0.0675392632398196 0.9461524058224456 1.0 1.0 7 Q02750 1 +Cytoskeleton organization 0.2577854838058315 0.0675288224409528 0.9461607173991212 1.0 1.0 371 Q15018,Q15691,P30153,Q9H2J4,O75351,O75400,Q14203,Q96CS2,Q9BVA1,Q9HC35,P04083,Q15004,P06753,Q9UQB8,P07437,P41208,Q86TU7,Q8IWJ2,Q9BPX3,Q99439,Q9UHD1,Q9UKS6,Q9HD42,Q00535,O95067,P43034,Q6UVJ0,Q7Z460,P15311,P24941,Q13526,P62826,P46108,P16949,P57737,P48729,Q96JJ3,Q9UHV9,Q9NZZ3,Q16527,Q9H6U6,P07737,Q14674,Q9Y2J2,Q16555,Q8TD16,P42858,Q12873,Q13177,O43379,Q9BV86,Q27J81,Q8N8S7,O43237,Q15257,Q15555,O75122,O14965,O60879,O75190,O94927,P04350,Q9UN37,P47755,P33981,Q12955,Q9Y266,Q16512,Q15813,Q86VS8,Q96AC1,P78559,P23396,A0AVF1,O60504,P67936,P46821,P49006,Q8IWC1,Q9P287,Q16204,P07196,Q9H6D7,Q15417,P35080,O95429,Q9HBM1,Q9UNF0,Q9Y4F1,Q9Y6G9,O43670,P49841,Q9BUF5,Q9NUQ9,P60981,Q86Y56,Q96HC4,Q6IBS0 98 +Positive regulation of fibroblast proliferation 0.2692986483120478 0.0672262524286184 0.946401585979159 1.0 1.0 6 Q00534 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.1943092937339537 0.0666064776599485 0.946894988773326 1.0 1.0 24 Q99497,Q99504,P49841,P61289,Q13546,P42858 6 +Negative regulation of myotube differentiation 0.3797838153666393 0.0658726505466873 0.9474792149784914 1.0 1.0 2 O15379 1 +Multicellular organismal response to stress 0.2675893253967951 0.06500439840878 0.9481704982401252 1.0 1.0 6 P42345,Q04637,P06730 3 +Monosaccharide metabolic process 0.1888653162102031 0.0647408032079531 0.9483803746878684 1.0 1.0 79 Q9UNI6,Q16539,O14874,P06744,Q9BYT8,P34949,P85037,P49841,Q9UKK9,Q96E52,Q9NQ88 11 +Nephron tubule epithelial cell differentiation 0.3737545113754595 0.0646982636801788 0.9484142453104188 1.0 1.0 3 O95747 1 +Renal vesicle development 0.3737545113754595 0.0646982636801788 0.9484142453104188 1.0 1.0 3 O95747 1 +Regulation of epithelial cell differentiation involved in kidney development 0.3737545113754595 0.0646982636801788 0.9484142453104188 1.0 1.0 3 O95747 1 +Regulation of cellular amide metabolic process 0.2091987158247583 0.0645517969600954 0.9485308650654452 1.0 1.0 199 Q9Y6E2,P00374,P05386,P13639,Q969T7,P62701,Q13131,P78344,P63241,P61221,Q96P11,P67809,Q14240,Q5TAX3,Q9BQC3,P16989,O43432,P08670,P15170,P04792,P49458,P98179,O15371,P18669,Q86U44,Q92615,Q13144,P26196,Q9HCE5,Q96C86,Q86W50,P04818,O15372,P34896,Q13526,P46777,P23588,Q9BPZ3,Q15056,Q14011,Q9Y450,P46199,P31751,Q04637,Q9Y6M1,Q92879,Q9Y5A9,Q9HCE1,Q96SZ6,Q96PZ0,P55010,P55884,P42345,P27635,P51114,P27695,P14618,P23396,P19525,Q92616,P62495,P49770,Q9UQ80,Q9Y2L1,P21399,P60228,Q9UBQ5,P46781,Q86UK7,O75794,Q6PKG0,P06730,A5YKK6,O75116,Q9BTV6,P78527,O60841,Q9BRX2,Q7Z739,Q7L1Q6,Q9NPI6,Q9NQ88 82 +Regulation of synapse maturation 0.3734658094681469 0.0644954334975316 0.9485757430844516 1.0 1.0 3 P63104,Q12834 2 +Myeloid cell development 0.2014769887043242 0.062615169131296 0.9500729499008074 1.0 1.0 17 P18074,Q15648,P62753,P43034,Q06124,Q96KR6,Q6NYC1 7 +Regulation of histone phosphorylation 0.2653111573617869 0.0621257024714778 0.9504627289159708 1.0 1.0 6 O43823 1 +Retina development in camera type eye 0.1989735088759306 0.0618951619397665 0.9506463203254644 1.0 1.0 19 Q15555,P83731,Q99471,Q15648,Q16706,Q6NYC1 6 +Magnesium ion homeostasis 0.3695985484109831 0.0618551866031598 0.950678155030812 1.0 1.0 3 Q12955 1 +Establishment or maintenance of bipolar cell polarity 0.201063472817937 0.0617961863833891 0.9507251405103644 1.0 1.0 17 Q9Y696,Q16658,P26038,P18085,Q12959,P61586,Q92796,Q8N3R9,O75083,P15311,P60953,O14745,Q13308,Q8WUM4 14 +Negative regulation of stem cell differentiation 0.237909185097115 0.0617951729699976 0.9507259475548582 1.0 1.0 8 P49841,Q9Y5A9,Q8WX92 3 +Rab protein signal transduction 0.2515535003576659 0.0617239873005786 0.950782637283988 1.0 1.0 7 Q9UL25,Q5VZ89 2 +Neuronal action potential 0.2825113716733761 0.0615222121058059 0.950943325207872 1.0 1.0 5 Q12955 1 +Synaptic transmission glutamatergic 0.2510239906378004 0.0609836481959644 0.9513722316645166 1.0 1.0 7 P54920,Q8NBU5,P21359,P19022,Q15042,Q00535 6 +Leukotriene biosynthetic process 0.369851007887821 0.0600055443957502 0.9521512188604084 1.0 1.0 2 P09960 1 +Stress granule disassembly 0.3667445938047938 0.0599967699498536 0.9521582072643776 1.0 1.0 3 P33176,Q07866 2 +Intraciliary transport 0.2634689990992552 0.0598662718483862 0.9522621428597 1.0 1.0 6 A0AVF1 1 +Regulation of organic acid transport 0.2164150691978797 0.059630892776485 0.952449613263204 1.0 1.0 11 P14174,Q15042,P31751 3 +Export from cell 0.179617700070159 0.0595284105049563 0.952531237284918 1.0 1.0 145 Q9UN37,Q99497,Q7Z6M1,O75351,O43768,Q06124,P35080,Q16512,P04083,Q9Y678,O95486,Q9UNH7,Q12765,P14174,Q15019,O95721,Q16850,P49841,Q86YV9,Q8NEB9,Q92783,Q4J6C6,Q15042,P20645,Q00535,Q92905,P43034,O75122,P0DP25,Q7Z460 30 +Receptor metabolic process 0.1785502599938336 0.0583879264605476 0.9534396316546092 1.0 1.0 39 Q13614,Q9NZZ3,P46934,Q96J02 4 +Protein localization to cilium 0.2001668646182855 0.0583583520725569 0.953463188434013 1.0 1.0 16 Q9UJY5,P18085,Q9UPT5,P50395,P49841,Q9NQ48,P36405,A0AVF1,Q9Y5K8,Q9H4M9 10 +Flavin containing compound metabolic process 0.3666374525270236 0.0582988528012391 0.95351058129475 1.0 1.0 2 Q8NFF5 1 +Establishment of sister chromatid cohesion 0.2905583162817858 0.0581240117268872 0.9536498481306196 1.0 1.0 4 Q9GZZ1,P06400,Q7Z5K2 3 +Regulation of respiratory burst 0.3636611241785682 0.0580727218871996 0.95369070249329 1.0 1.0 3 P39019 1 +Purine nucleoside monophosphate catabolic process 0.3631639212386493 0.057770488316127 0.9539314458172184 1.0 1.0 3 P00491 1 +Ribonucleoside monophosphate catabolic process 0.3631639212386493 0.057770488316127 0.9539314458172184 1.0 1.0 3 P00491 1 +Embryonic hindlimb morphogenesis 0.3592150032372248 0.0554475228759814 0.9557819362632236 1.0 1.0 3 O95747 1 +Hindlimb morphogenesis 0.3592150032372248 0.0554475228759814 0.9557819362632236 1.0 1.0 3 O95747 1 +Bone cell development 0.2595117127544706 0.055216235447113 0.9559661946511192 1.0 1.0 6 P43034,Q06124 2 +Udp glucose metabolic process 0.357977790765634 0.0547475908570432 0.9563395541689932 1.0 1.0 3 P49840,Q16851 2 +Positive regulation of cellular protein catabolic process 0.1798953263141696 0.0547284557077085 0.9563547989534976 1.0 1.0 54 P62191,P26038,Q92995,P15311,P43686,Q15370,P48729,P62333,P17980,P62195,P49841,O75150,P35241,O75832,P54725,O14965,Q9Y5A7,P07900,Q9UNN5 19 +Mitochondrial fission 0.1999821417031535 0.0536235642836625 0.957235081936129 1.0 1.0 15 Q9Y3D6,O00203,Q9NUQ9,Q27J81,O14965 5 +Tight junction organization 0.1904202174551877 0.0535396122381221 0.957301969890934 1.0 1.0 22 O00159,Q12959,Q13464,O75970,Q5T2T1,Q07157,P17252,P55196,Q15149,P51153,Q9H8V3,P17612,Q9BTW9,Q13112,O43815,O75116,Q13177,Q8WUM4,Q16625,P36404,O14920 21 +Regulation of cytoplasmic translational elongation 0.2843773329781335 0.0532820916942879 0.9575071486888264 1.0 1.0 4 Q9BTV6 1 +Response to pain 0.3552336148502666 0.0532415030911424 0.95753948780596 1.0 1.0 3 P42345 1 +Behavioral response to pain 0.3552336148502666 0.0532415030911424 0.95753948780596 1.0 1.0 3 P42345 1 +Mrna splice site selection 0.1914651318466241 0.0526957219126853 0.9579743477108014 1.0 1.0 21 Q9Y383,Q9ULR0,Q13243 3 +Inflammasome complex assembly 0.3535943892460598 0.0523718518938147 0.9582324022623256 1.0 1.0 3 P19525,Q9H6R0 2 +Synaptic transmission dopaminergic 0.2567766323315517 0.0521621294960367 0.9583995081162155 1.0 1.0 6 Q00535 1 +Keratinocyte development 0.3524254821741651 0.0517651979845866 0.9587157863396748 1.0 1.0 3 Q15149,Q8WX93 2 +Neuron projection extension involved in neuron projection guidance 0.352133255406191 0.0516152716610607 0.9588352505346897 1.0 1.0 3 Q13740,O14786 2 +Regulation of stem cell differentiation 0.1891175911718295 0.0511994866916416 0.9591665608706604 1.0 1.0 22 Q00534,Q9Y5A9,P49841,Q96PZ0,Q96J02,P78527,P19525,Q8WX92 8 +Positive regulation of cell size 0.3501946483499834 0.0506380844829326 0.9596139147112251 1.0 1.0 3 P08238 1 +Regulation of lamellipodium assembly 0.1956568898262068 0.0501150562625737 0.9600307016519838 1.0 1.0 16 O15144,Q16658,P50570,P61160,P42345,P60953,Q6IBS0,P47756,Q12792 9 +Positive regulation of histone deacetylation 0.2300304508856482 0.0500217969179322 0.9601050186341292 1.0 1.0 8 O43823 1 +Positive regulation of protein deacetylation 0.2300304508856482 0.0500217969179322 0.9601050186341292 1.0 1.0 8 O43823 1 +Metanephric nephron development 0.2795727504921171 0.0498382683897311 0.9602512707954584 1.0 1.0 4 O95747 1 +Cell differentiation involved in metanephros development 0.2795727504921171 0.0498382683897311 0.9602512707954584 1.0 1.0 4 O95747 1 +Activation of innate immune response 0.1924289984998498 0.0497325823364301 0.9603354916265434 1.0 1.0 19 P09429,Q16512 2 +Positive regulation of dna biosynthetic process 0.1733707672000226 0.0488736210543228 0.9610200110815372 1.0 1.0 34 Q96HR8,Q9BRT9 2 +Regulation of tor signaling 0.1889730323934584 0.048325224668083 0.9614570516570488 1.0 1.0 21 P10398 1 +Positive regulation of production of molecular mediator of immune response 0.1854679957251333 0.0477091556763984 0.9619480372391718 1.0 1.0 23 P06744,P14174,O96028,O95999 4 +Negative regulation of single stranded viral rna replication via double stranded dna intermediate 0.2756503946214486 0.0472256908921389 0.9623333519906928 1.0 1.0 4 Q9UK61,Q15047,Q13263 3 +Cellular anion homeostasis 0.3417548833217448 0.0467247659426226 0.9627325915313918 1.0 1.0 3 P12277 1 +Glomerular epithelial cell development 0.3377154542798682 0.0465888124339472 0.9628409487336484 1.0 1.0 2 P46940 1 +Protein containing complex disassembly 0.1908950348348598 0.0464339979349634 0.9629643392937784 1.0 1.0 104 Q9UN37,O75351,P63241,P16949,Q01105,Q08945,Q9NZZ3,P78559,Q13137,O95721,P53990,P49841,Q8NEB9,Q9BPX3,Q9HD42,P46821,P60981,Q6IBS0,O75122,Q7Z460 20 +Glucose catabolic process 0.2146134856832009 0.0462689490030786 0.96309588789883 1.0 1.0 10 P85037 1 +T cell lineage commitment 0.2650618789715213 0.0457896664892521 0.9634778951199894 1.0 1.0 5 P42345 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 1.0 2 P04439 1 +Regulation of immune system process 0.2091850232648919 0.0452346625015891 0.9639202658360604 1.0 1.0 204 Q96FZ2,Q99497,P62942,Q14232,P98170,O95251,Q06124,P28070,P15311,Q9GZS3,Q96J02,O43251,P46108,P51617,Q16512,P30046,P09429,Q16539,P19474,Q6SZW1,Q00534,Q9H4A3,Q9NR50,P04083,Q9Y3Z3,Q16543,Q9NUD5,O96028,P14174,P23396,P06744,P08238,P46109,P39019,Q13177,O00203,Q9GZP4,Q9NUQ9,O14617,Q13546,Q01804,Q9Y5A9,P00491,O15347,P49770,O95999,Q7Z739,Q13144,P51452,O95747,P25786 51 +Regulation of cell cycle phase transition 0.1814135077632437 0.0451212956264446 0.9640106272522512 1.0 1.0 127 Q9UN37,O75351,P33981,P42771,Q06124,P15927,P24941,Q16539,Q96K76,Q15645,Q9NVH2,P04083,Q13535,Q9NWV8,Q14674,Q9P258,Q9UNS1,Q9Y6G9,O60921,P31350,O43670,Q969U7,Q96RU2,Q04637,P61289,Q9NZJ0,Q9UL46,Q9BXW9,O95905,Q96DY7,Q6UVJ0 31 +Glomerular epithelial cell differentiation 0.3378141437755703 0.0450785839174583 0.9640446716245978 1.0 1.0 3 P80723,P46940 2 +Negative regulation of organic acid transport 0.3374836283549768 0.0449455274507874 0.9641507278310996 1.0 1.0 3 P31751 1 +Mechanoreceptor differentiation 0.205205242313787 0.044362148605446 0.9646157329650916 1.0 1.0 11 Q9Y6M7,O95487 2 +Positive regulation of cell junction assembly 0.1966012305889177 0.0441696374879347 0.9647691841981394 1.0 1.0 12 O95819,Q13641,O14786,O75955,Q9NUL3,P41440,Q13464,Q96AC1,Q9HCM4,P63000,Q9H2P0 11 +Alditol metabolic process 0.2373009641545543 0.0437706381438104 0.9650872320112956 1.0 1.0 7 P60174,A6NDG6,P51570,P17174 4 +Peptidyl diphthamide biosynthetic process from peptidyl histidine 0.3338888331421556 0.0435470416030561 0.9652654662919976 1.0 1.0 3 Q9BTV6 1 +Positive regulation of attachment of spindle microtubules to kinetochore 0.2668810289389013 0.0419973081054707 0.9665008440461332 1.0 1.0 4 P14635,Q9P258,Q00839 3 +Negative regulation of biomineralization 0.3287551139684406 0.0416993148898218 0.9667384001264006 1.0 1.0 3 Q13464,O75116 2 +Adherens junction assembly 0.266311061030561 0.041685527179377 0.9667493915705578 1.0 1.0 4 P18206,Q13177 2 +Tumor necrosis factor mediated signaling pathway 0.1914701757155257 0.040467401168662 0.9677204958415332 1.0 1.0 15 P63241,P98170 2 +Transcription elongation from rna polymerase i promoter 0.3249561659848063 0.040439812337712 0.967742490539334 1.0 1.0 3 P18074,P19447 2 +Regulation of cytoplasmic mrna processing body assembly 0.3234950321449459 0.0399788041329846 0.9681100246324714 1.0 1.0 3 A5YKK6,Q9HBH5 2 +Negative regulation of arp2 3 complex mediated actin nucleation 0.3079170318434076 0.0398704585728419 0.9681964030121176 1.0 1.0 2 P60983 1 +Negative regulation of actin nucleation 0.3079170318434076 0.0398704585728419 0.9681964030121176 1.0 1.0 2 P60983 1 +Regulation of vesicle mediated transport 0.1750622298864877 0.0398130817440379 0.9682421467774868 1.0 1.0 134 P17931,Q9UN37,O14964,P26038,O75351,P36507,Q96T51,O60493,P15311,Q13131,O00560,P35080,Q06787,P09429,P61978,Q9HD26,P61020,Q02750,P50570,P04083,P27695,Q15036,Q9UNF0,Q9H3U1,Q9H223,Q15019,Q96PU5,P31751,O75165,P49841,P11274,Q92783,Q4J6C6,P35241,Q99439,O60343,Q9UKS6,Q15042,Q9NT62,Q00535,P41240,Q13614,Q9UMY4,Q9NR31,Q7Z3T8,Q6IQ22,Q8N6T3,P62330,O75122,P11233,Q9UL25,P0DP25,Q7Z460,Q9H4M9,Q9Y5K6 55 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3223375215741787 0.0396225856119712 0.9683940208615076 1.0 1.0 3 Q99497 1 +Posttranscriptional regulation of gene expression 0.2217825517706529 0.0384016873510217 0.969367415664363 1.0 1.0 235 Q9Y6E2,P00374,Q9HCE5,Q96C86,P42345,Q86W50,P51114,P36507,Q9UBQ5,Q969T7,Q9UPY3,Q9HAV4,P62826,P63241,Q96P11,P67809,Q96HR8,Q9H814,O75794,Q16539,P23588,Q02750,Q5TAX3,Q16543,Q9BPZ3,Q15056,Q14011,Q9Y450,P23396,P46199,P16989,P31751,P04792,Q04637,Q9BTV6,Q9Y6M1,Q15631,Q13546,P98179,Q92879,Q99598,O15371,P49770,Q9Y5A9,O60841,Q9HCE1,Q96SZ6,Q7Z739,Q9Y2L1,Q96PZ0,P55010,Q13144,P55884,Q7L1Q6,Q9NPI6 55 +Radial glial cell differentiation 0.2546783625731055 0.0383725141769093 0.9693906753458824 1.0 1.0 5 Q86U44,P40763,P61586,Q9HCE5 4 +Membrane raft localization 0.2953549517966621 0.0381704461953527 0.9695517842365148 1.0 1.0 2 P11233 1 +Ribonucleoside diphosphate biosynthetic process 0.2317144528964271 0.0378084216170909 0.9698404296952556 1.0 1.0 7 P11172,Q05682,P30085,P00568,P27708,Q02127 6 +Positive regulation of protein localization to nucleus 0.1715968769325308 0.0374582127532257 0.970119658138384 1.0 1.0 41 Q16539,P08238,Q99497,Q96D46,P17987,P78371,O75312,O95817,Q96AC1,O95251,O15379,Q13263,Q9Y5K6,P62826,Q9H8V3,Q4G0J3,Q8TDB6,P06493 18 +Cellular response to cold 0.3135593220339029 0.0371676200863552 0.970351356192555 1.0 1.0 3 P17612,P17252 2 +Positive regulation of translation in response to endoplasmic reticulum stress 0.3135593220339028 0.0371676200863552 0.970351356192555 1.0 1.0 3 Q04637,O00571 2 +Positive regulation of translation in response to stress 0.3135593220339028 0.0371676200863552 0.970351356192555 1.0 1.0 3 Q04637,O00571 2 +Positive regulation of chromatin organization 0.2148711943793904 0.036390852908489 0.9709707076716948 1.0 1.0 9 Q6VMQ6,P12270,Q9UK61,Q9Y6X9,Q15047,P24941,Q13263,P26358 8 +Synaptic transmission gabaergic 0.2508771929824586 0.0359878021420817 0.9712920851355392 1.0 1.0 5 P33176,P21359,P27695,Q13641 4 +Neural tube patterning 0.2522654194679856 0.0349957361836206 0.9720831408248888 1.0 1.0 4 P26367,P17612,P17252 3 +Dicarboxylic acid catabolic process 0.2288716815372782 0.0349945380349327 0.97208409622403 1.0 1.0 7 P17174 1 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.251388482899732 0.0346376218561923 0.9723687015852198 1.0 1.0 4 P08238,O00560,Q13573 3 +Leukocyte mediated cytotoxicity 0.1853664058075701 0.0339015519110778 0.9729556556548672 1.0 1.0 16 P46108,Q9NUQ9 2 +Smoothened signaling pathway 0.1762626836709043 0.0337304269246198 0.9730921155946408 1.0 1.0 23 Q4G0X4,A0AVF1 2 +Negative regulation of response to dna damage stimulus 0.1719574698722557 0.0335179098092771 0.9732615838933454 1.0 1.0 28 P23396,Q96K76,O75832,Q96FW1 4 +Negative regulation of leukocyte migration 0.2361078920842393 0.0330510808134205 0.9736338532704378 1.0 1.0 6 P30046 1 +Fear response 0.2921949304998918 0.0327721242754462 0.9738563078733964 1.0 1.0 3 Q04637 1 +Branching involved in mammary gland duct morphogenesis 0.2910578609000606 0.0325917785995265 0.9740001260762856 1.0 1.0 3 Q15648,Q99623 2 +Mesoderm development 0.1854832884233074 0.0325392080542397 0.9740420490669196 1.0 1.0 15 P06744,Q96PZ0,O95747,P17612 4 +Peptidyl lysine monomethylation 0.2897295727871475 0.032387116579361 0.9741633365797556 1.0 1.0 3 Q86TU7 1 +Locomotor rhythm 0.2874524306470414 0.0320509260191699 0.9744314386461084 1.0 1.0 3 P42345 1 +Positive regulation of myeloid leukocyte differentiation 0.2412280701754383 0.0306671357091305 0.9755350007331416 1.0 1.0 5 Q00613,P06400,Q13546,P17252 4 +Response to copper ion 0.2142117184459203 0.030618681149151 0.9755736437315335 1.0 1.0 8 Q99497,Q00796,Q9UER7,Q00613,P06493 5 +Auditory receptor cell morphogenesis 0.2394036831335813 0.0303678033913657 0.9757737221787142 1.0 1.0 4 Q14160,O95487,O14745 3 +Inner ear receptor cell stereocilium organization 0.2394736842105269 0.0298063634072138 0.97622148375795 1.0 1.0 5 Q9BW83,Q14160,O95487,O14745 4 +Positive regulation of lyase activity 0.2621274108708407 0.0293660290940895 0.9765726659690608 1.0 1.0 3 P21359,Q99497 2 +Positive regulation of cellular respiration 0.2621274108708407 0.0293660290940895 0.9765726659690608 1.0 1.0 3 P55072,Q99497 2 +Negative regulation of cell cycle phase transition 0.1800264953372481 0.02931947410793 0.9766097954860986 1.0 1.0 76 Q16539,Q9UN37,Q96K76,O43670,Q15645,Q9NVH2,Q969U7,Q96RU2,P33981,Q13535,Q06124,P15927,Q9UNS1,P24941,Q9Y6G9,Q9NZJ0,O60921 17 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.2545295149035701 0.0288605418409452 0.9769758155520838 1.0 1.0 3 Q9BY67,Q13740 2 +Substrate dependent cell migration 0.2085232920045328 0.0287938292423673 0.9770290223922784 1.0 1.0 9 Q14247,Q13043,O00560,Q9Y5K6 4 +Protein import into peroxisome membrane 0.253068381063711 0.0287756385855558 0.9770435304248596 1.0 1.0 3 P40855,P50542 2 +Carbohydrate biosynthetic process 0.1692977705652265 0.0287459909414038 0.977067176040726 1.0 1.0 47 Q9BYT8,P06744,O43505,P13807,P31751,P49841,A6NDG6,Q13043,P46976,P17174 10 +Positive regulation of gliogenesis 0.2083357997735277 0.0285832725354624 0.9771969532170588 1.0 1.0 9 Q9UPY3 1 +Positive regulation of secretion 0.1709859599429724 0.0284060718482523 0.9773382815222142 1.0 1.0 50 Q9UN37,O75351,Q92783,Q06124,O95486,O75122,P14174,Q15042,Q9Y5X3,Q7Z460,Q00535 11 +Regulation of execution phase of apoptosis 0.2369959088252538 0.0280572412658704 0.9776164971621182 1.0 1.0 3 O00273,Q13177 2 +Regulation of transcription elongation from rna polymerase ii promoter 0.1797679984038295 0.0276912628336705 0.9779083922816508 1.0 1.0 17 P18615,P55199,P35269,Q9Y5B9,Q8IXH7,Q9NYV4,Q4G0J3,Q8WX92 8 +Translesion synthesis 0.1983225167066938 0.0273088290194822 0.9782134149567694 1.0 1.0 10 Q9NZJ0,P56282,P12004,Q15004 4 +Integrin mediated signaling pathway 0.1783780001247428 0.0272942652613718 0.9782250308246204 1.0 1.0 18 Q96AC1,Q06124,P22392 3 +Regulation of protein exit from endoplasmic reticulum 0.2200627638525447 0.0271725124103105 0.978322139527281 1.0 1.0 7 Q9NR31 1 +Phosphorylation 0.2525017288442302 0.0257219605997904 0.9794791076250569 1.0 1.0 361 P30153,Q9H2J4,P04183,Q06124,P61201,Q13043,Q9HA64,P35790,Q16539,Q9HBU6,P31689,Q53EL6,O60271,Q14012,P14174,O60921,Q05639,Q9UNI6,Q96C90,P78356,Q96M27,P04792,O75832,Q9UHD1,Q13546,Q00535,O14874,Q96Q15,P12277,P18669,O95067,P10398,P0DP25,Q7Z460,Q96A49,Q99497,Q99570,P36507,P23919,P24941,Q13526,P51617,P60891,P48729,P42356,Q8TF05,Q9NYB0,Q9NY27,Q13535,Q9Y4R8,Q96KB5,P42858,P15531,P08238,P31751,P36871,Q13177,Q9Y3D8,Q96SZ6,P51452,P51114,P33981,P42771,Q96B36,Q93062,Q16512,Q16543,Q96AC1,Q9UNH7,P23396,P06744,P46109,Q8NEB9,P22392,Q96SB4,Q9P287,Q9UJ70,Q9Y223,O95747,P11908,Q8IV63,P35080,O43823,O95429,P85037,Q00534,Q02750,Q13572,Q9H4A3,Q86Y37,O95373,P49841,O95999,Q9NQ88 94 +Cerebral cortex neuron differentiation 0.2201754809710116 0.0255976546074979 0.9795782568104978 1.0 1.0 4 P43034 1 +Mesoderm morphogenesis 0.1962445628154424 0.0253171637722731 0.979801983608494 1.0 1.0 10 P06744,P17612 2 +Organonitrogen compound catabolic process 0.2548325149001661 0.0244605969968713 0.980485213344723 1.0 1.0 404 Q9H773,Q9H2J4,O75351,P49721,P28070,Q13200,Q96E52,Q15370,Q96K76,P20618,Q9Y3Z3,Q13126,Q9BQG2,Q05639,Q96PU5,Q4G0X4,Q16850,Q96RU2,O75832,Q9UKS6,P46934,Q13546,Q9HD42,O14874,P00491,Q6P179,P33316,P54727,P28072,P10398,Q13309,P49720,Q04323,Q9UBU6,Q8IYU2,Q93034,Q9UJY5,Q99497,O95155,P15586,Q92995,Q8WW12,P16930,O60493,P15311,Q9H1I8,P28074,P24941,Q13526,Q6SZW1,P48729,Q9NZZ3,Q8N511,Q8N3C0,P60900,Q96KB5,Q16555,P25788,P08238,Q99436,O95817,Q13107,P68036,Q9GZP4,P61289,Q7Z6Z7,Q8NBM8,P28066,P49427,P62081,Q9UNS2,Q96RL7,Q6QHF9,O60502,P13051,O95260,Q9UN37,Q8WUX2,P51665,O43847,Q96J02,P48556,P62333,Q9NXV2,Q13596,P78559,P25789,Q92783,Q15386,P17174,Q9UJ70,P54725,O94966,P25786,O43242,Q9UNM6,Q5T4S7,Q9UHG3,Q86Y37,O43598,P25787,P49841,P53004,P40818,Q9NZJ0,Q9UL46,Q9Y5X3,O75600,O94888,Q5VWZ2,Q9UNN5 111 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.2008184741303649 0.0227376029684677 0.9818595807504528 1.0 1.0 4 P09874,Q99497,Q07820 3 +Response to carbohydrate 0.1651789258801923 0.0224962357235655 0.982052114698911 1.0 1.0 40 Q6SZW1,P46821,P49770,Q99808,Q14232,Q9NR50,P48163,O95251,Q13144,P17612 10 +Regulation of small gtpase mediated signal transduction 0.1660295823753966 0.022340672364172 0.9821762051144344 1.0 1.0 43 Q5VZ89,Q15555,Q9NUQ9,P46108,P16949 5 +Histone h2a phosphorylation 0.2202852676431808 0.0222730544905709 0.9822301429505051 1.0 1.0 5 Q13043 1 +Positive regulation of chemokine production 0.2051168631371325 0.0218252005579844 0.9825873918344928 1.0 1.0 8 P09429,P14174 2 +Negative regulation of cell cycle process 0.1836287491812828 0.0208697634897519 0.9833495466086076 1.0 1.0 87 Q9UN37,P33981,Q06124,P15927,P24941,Q16539,Q96K76,Q15645,Q9NVH2,Q13535,Q14674,Q9UNS1,Q9Y6G9,O60921,O43670,Q969U7,Q96RU2,Q9NZJ0,P41227,Q96DY7 20 +Positive regulation of cytokine production involved in immune response 0.1906295754026342 0.0203793779669149 0.9837407344330004 1.0 1.0 10 Q9NR30,Q96EB6,O95999,P04439,Q9H2U1,Q7Z434,Q92499,P14174,Q9NY93 9 +Apical junction assembly 0.1644117647058827 0.0199965192178278 0.9840461492732504 1.0 1.0 25 O00159,Q12959,Q13464,O75083,Q5T2T1,Q07157,P17252,P55196,P51153,Q9H8V3,P17612,Q9BTW9,Q13112,O43815,O75116,Q13177,P18206,P25054,Q8WUM4,Q16625,Q16513,P36404,P61586,O14920 24 +Establishment of tissue polarity 0.1896496504160688 0.0195818110957055 0.984376973695168 1.0 1.0 10 O95487 1 +Glial cell apoptotic process 0.2056758338209459 0.0170728963043196 0.986378461376756 1.0 1.0 7 P06400,Q02952,P17252,P42574,P04637,Q00535 6 +Aldehyde catabolic process 0.1920749031454763 0.0160955551713821 0.9871581595162237 1.0 1.0 5 P10768,Q99497 2 +Autophagy of nucleus 0.1836257309941528 0.0150459066809949 0.9879955562839388 1.0 1.0 5 Q9Y4P8,Q9NT62,Q7Z3C6,O95352 4 +Macroautophagy 0.1826011883510043 0.0139528393970175 0.9888676060792092 1.0 1.0 115 Q9GZZ9,Q9UN37,O75351,O75436,Q86YR5,P50851,Q9NZZ3,Q16543,Q9UNH7,Q13137,P42858,O95721,P78356,Q8NEB9,O95817,Q92783,Q15042,Q9NT62,Q8NCE2,P46934,Q9Y5X3,Q9HD42,Q96Q15,Q9NQ88 24 +Regulation of chromatin binding 0.196266114791469 0.012045329825641 0.9903894497019814 1.0 1.0 7 O14981 1 +Maintenance of cell number 0.1523249882796465 0.0104069571929406 0.991696599414052 1.0 1.0 33 O60244,Q5TAX3,Q86VS8 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.1851418543433671 0.009532714052534 0.9923941098296588 1.0 1.0 6 P61978,O60341,Q96EB6,P14174,Q9HBM6 5 +Regulation of endocytosis 0.1648626976226914 0.0047900796473129 0.996178084019955 1.0 1.0 54 P17931,Q96T51,O00560,Q06787,P61978,P61020,P50570,Q15036,Q9UNF0,Q9H3U1,Q9H223,Q96PU5,Q9UKS6,Q13614,Q9UMY4,Q7Z3T8,Q8N6T3,P62330,Q9UL25,P0DP25,Q9Y5K6 21 +Heart development 0.1807813598932584 0.0040042998065199 0.9968050395457756 1.0 1.0 90 P13807,Q16539,P62942,Q02750,P46109,Q15036,Q9HB71,Q96HC4,Q06124,Q53EL6,Q13043,O95487,O96028,O95747,Q6NYC1 15 +Regulation of embryonic development 0.146549192364168 0.0035550373476299 0.9971634965620088 1.0 1.0 20 Q9H0H5,Q16181,Q4VCS5,P35222,P46379,Q9H9B1,Q9H2U1,P23528,P63244,Q9Y4C8,Q68CQ4,P43034,Q96TA1,P61106,O75122,O95747,Q7Z460,Q6KC79,P06493 19 +Amino acid activation 0.1497878138142718 0.0001886432027599 0.99984948450191 1.0 1.0 37 Q9HA77,P54577,P49589,Q9Y285,P26639,Q9BTE6,P26640,P49591,Q9NSD9,A2RTX5,O43776 11 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4e333bc8a7e532a0d128d4c08fd3145607ab7a97 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp catabolic process", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chorionic trophoblast cell differentiation", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Cornea development in camera type eye", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of temperature stimulus", "Detection of temperature stimulus involved in sensory perception", "Detection of temperature stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic camera type eye morphogenesis", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic eye morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iris morphogenesis", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fat cell proliferation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Negative t cell selection", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic a cell differentiation", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chondrocyte proliferation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of mucus secretion", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked deubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine biosynthetic process", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of artery morphogenesis", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of asymmetric cell division", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to fluoride", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to water deprivation", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of temperature stimulus", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymic t cell selection", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPV", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COASY", "COG3", "COG4", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM192A", "FAM208A", "FAM210B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS27", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC28", "TTC37", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UIMC1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDHD1", "WDR1", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM4", "ZNF207", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "ABCC4", "ABCD3", "ABCE1", "ABRACL", "ABRAXAS2", "ABT1", "ACO1", "ACP6", "ACTN1", "ACTR10", "ACTR2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADSS", "AFDN", "AGL", "AHCYL1", "AHSA1", "AIFM1", "AIMP2", "AIP", "AK1", "AK6", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDOA", "AMOT", "AMPD2", "ANK3", "ANLN", "ANP32B", "ANP32E", "ANXA1", "AP1M1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APC", "APEX1", "API5", "APRT", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARL2", "ARL3", "ARMC6", "ARMC8", "ARPC2", "ARPC3", "ARRB1", "ARRB2", "AS3MT", "ASCC2", "ASCC3", "ASH2L", "ASNS", "ASRGL1", "ATAD1", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATP6V1D", "ATR", "ATXN2L", "AURKA", "B3GAT3", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BCAS3", "BCCIP", "BCKDK", "BCL10", "BCR", "BICD2", "BLVRA", "BOP1", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BYSL", "BZW1", "BZW2", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK1", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CAST", "CBL", "CBX8", "CCDC124", "CCDC22", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CDC123", "CDC20", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKN2A", "CELF1", "CENPI", "CERS2", "CETN2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHMP5", "CHORDC1", "CHUK", "CIRBP", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLIC4", "CLINT1", "CLUH", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "COG4", "COG5", "COG7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS5", "COPS6", "COPS7A", "COPZ1", "CORO7", "COTL1", "CPNE8", "CPPED1", "CPSF7", "CPVL", "CRK", "CRKL", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CTBP1", "CTNNB1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTTNBP2NL", "CUL1", "CUL3", "CUL4B", "CUL5", "CUTA", "CYFIP1", "CYP51A1", "DAXX", "DCAF1", "DCAF16", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTPP1", "DCUN1D1", "DDB1", "DDT", "DDX1", "DDX21", "DDX28", "DDX3X", "DDX56", "DDX6", "DENND4C", "DENR", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX30", "DHX33", "DHX36", "DHX8", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLG1", "DLG3", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK6", "DPH2", "DPH7", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG2", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "E2F3", "EBP", "ECD", "ECT2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3J", "EIF3K", "EIF3L", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", 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"GTF2E1", "GTF2F1", "GTF2F2", "GTPBP3", "GYG1", "GYS1", "HACE1", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HBS1L", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HECTD1", "HERC5", "HGS", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HNRNPAB", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSF1", "HSP90AA1", "HSP90AB1", "HSPB1", "HSPBP1", "HTATSF1", "HTT", "HUS1", "HUWE1", "IARS", "IARS2", "IDH1", "IDH2", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGHMBP2", "IKBKB", "IMPDH2", "INA", "INF2", "INPPL1", "INTS7", "IPO7", "IPO9", "IQCB1", "IQGAP1", "IRAK1", "IRF2BPL", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IWS1", "JMJD6", "KAT7", "KCTD21", "KCTD5", "KDELR1", "KDM1A", "KIAA0368", "KIF11", "KIF13B", "KIF1A", "KIF3A", "KIF5B", "KIFBP", "KLC1", "KPNA1", "KPNA6", "LANCL1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LGALS3", "LIG1", "LIMA1", "LLGL1", "LNPK", "LRBA", "LRWD1", "LTA4H", "LTV1", "LUC7L2", "LYN", 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0.3184279071165019 1.0 1.0 1.0 0.0004628530549595 8.641434277596474e-08 +Site of polarized growth 28 52 2.49514012852479 0.0125907397280924 12.407766990291265 48.44417475728155 0.0465719733262774 0.6407527041886554 6.134712459065642 5.7567427791912475 0.8677611137018515 0.3206519581677468 1.0 0.4606405324486534 0.3561708686960925 0.3896513526450025 0.2985331074252403 +9plus0 non motile cilium 6 12 2.417080746447958 0.0156455459938118 2.9563106796116503 10.565533980582524 0.0567939925419757 0.6387556435852088 1.7551682298653493 2.455047595352738 0.7048407975451683 0.2729556486060043 1.0 1.0 0.4353012614103685 0.1728856135395864 0.0236488585480569 +Retromer complex 7 10 2.3909442248951165 0.0168051056032676 3.8932038834951457 8.861650485436893 -0.0417011237299978 0.5913523591909454 2.2999055335569523 0.9541860732087792 0.848315533513102 0.3034434293986225 1.0 1.0 1.0 1.0 0.0001590313802548 +Magnesium dependent protein serine threonine phosphatase complex 6 9 2.3605346108598524 0.0182486153812928 3.570388349514563 8.978155339805825 -0.0595363192103511 0.4977467020976059 2.2246188382278542 1.688628010662448 1.0072225680138365 0.3114796997303573 1.0 1.0 1.0 0.4732445906533414 0.3630866560691931 +Distal axon 30 59 2.323467106203711 0.0201540727509297 14.37621359223301 56.932038834951456 0.087742779329781 0.64290004839216 6.757715276645177 6.171516368750388 0.8600493637808696 0.3236313299944118 1.0 0.5525292180527084 0.4855210477597627 0.5921832080594684 0.4392601107137406 +Ciliary transition zone 6 8 2.267692858510082 0.0233479334356179 1.9635922330097089 6.907766990291262 0.9295898692526422 0.3532985326295446 1.5457849700174688 1.7711928579014855 0.854807445224746 0.2896111184937897 1.0 1.0 0.3955810682553247 0.1323508586296182 0.1072426750643267 +Dynein complex 5 11 2.256308222129324 0.0240513348255286 3.779126213592233 11.347087378640778 0.0137775724407904 0.5955821430721882 2.3039120831713062 1.5867828667311044 0.8314129562783991 0.2933565758209187 1.0 1.0 1.0 0.1562190614045352 0.0501437556032915 +Cytoplasmic dynein complex 4 9 2.209406459914778 0.027146382115545 3.25 9.347087378640778 -0.1273459533679964 0.5459837817037768 2.0260739690730296 1.5867828667311044 0.902838569499687 0.300732072386452 1.0 1.0 1.0 0.0768284795296569 0.0119688845689888 +Cytosolic region 2 7 2.198416414709754 0.0279194450087203 1.366504854368932 7.070388349514563 0.5536869130722247 0.5032773557513882 1.7568574154244203 0.9123727971774008 0.8120760560829308 0.3021289957314627 1.0 1.0 0.1180585699575878 0.0033939033653995 0.0227185425065092 +Postsynaptic cytosol 2 6 2.1695018106339883 0.0300446070465472 1.0655339805825244 5.839805825242719 0.6842461209696534 0.4705435342470324 1.4888180156744395 0.7231054665083247 0.8090294271856947 0.3031424553191165 1.0 1.0 0.0921025797166938 0.0015031185668187 0.0106255777102749 +Podosome 8 13 2.155062430975926 0.0311569491152932 4.861650485436893 11.259708737864075 -0.3784244638548238 0.5619411282160642 2.547182946947119 0.8232235434831835 0.821211051258118 0.315198304024495 1.0 1.0 1.0 1.0 0.682815470497098 +Postsynaptic density membrane 0 6 2.150657232973509 0.0315032643160204 1.8106796116504855 6.669902912621359 0.9700827983290172 0.2992953748741365 1.3610684424812354 1.822930264123012 0.935271302642404 0.2569047527325972 1.0 0.1524760813950871 0.2872333566147377 0.5782306803788487 0.8259524853648126 +Photoreceptor connecting cilium 4 6 2.147337932366934 0.031766388047187 1.575242718446602 4.742718446601942 0.3441316768755689 0.5081118640708276 1.2154621516355948 1.2778244513604653 0.9033077490026462 0.3044846385557425 1.0 1.0 0.2518545844225215 0.0356014336373073 0.0138780941766985 +Neuron to neuron synapse 19 67 2.117250523017183 0.034238591568841 13.283980582524272 62.51699029126213 0.0452447961299691 0.7244268272439499 6.738487894655527 6.035670880729685 0.6463748499647565 0.2876123842093391 1.0 0.644780089608989 0.3468352540469536 0.6117393556758833 0.3659259780439142 +Cop9 signalosome 4 10 2.0776714402919016 0.0377396312493369 3.941747572815534 9.973300970873789 0.4241777023556705 0.527656079235931 2.265508548830528 0.9226206747176942 0.8805653912147905 0.3225039510318988 1.0 1.0 0.1094892401774078 0.2559514735144251 0.0020033682110678 +Centriole 12 27 2.043757439732754 0.0409775156075373 7.177184466019417 25.56553398058253 -0.0477360182303363 0.6746277013913514 4.101877836004659 4.604564689197087 0.674226498955594 0.2826723776990107 1.0 1.0 0.6821824234140106 0.1600758420276832 0.5155318189430033 +Spindle microtubule 14 37 2.0329158691856173 0.0420610234817486 8.987864077669903 32.45145631067961 -0.0864460535037169 0.6844593359560065 4.354146366794169 4.566134607937 0.7169464458075635 0.296348916206594 1.0 0.2989716991852097 0.162236447621752 0.0096888119633368 0.0716032196730593 +Prefoldin complex 4 5 2.0249870114434585 0.0428686979562704 2.0 4.558252427184466 0.6613596346898009 0.3787606197734878 1.2637592249478444 0.939430138341434 1.0491603610968223 0.3009247811837955 1.0 1.0 1.0 0.0004628530549595 0.0001722011086768 +Vesicle lumen 47 125 1.9718978678270176 0.0486212667628851 28.93446601941747 119.79368932038837 -0.0708316930912348 0.5682496130595786 13.122391611595372 7.240907185867801 1.2978103845669404 0.3622974798457447 1.0 0.0684135745750349 0.128026117966102 0.0036902178216933 0.0001149034626724 +Protein phosphatase type 2a complex 4 6 1.965230012814787 0.0493876217407789 2.516990291262136 5.669902912621359 0.299168775918065 0.508393987248413 1.5223903885177978 0.8717614075761149 0.9411397025089426 0.3137875197040505 1.0 1.0 1.0 0.3258327648280404 0.1812716861639223 +Postsynaptic specialization membrane 0 10 1.9643336359199095 0.0494914134298287 2.4199029126213594 10.24271844660194 0.7861101002372709 0.3813630835285081 1.6578416165380507 2.0900412009571863 0.9115241808638076 0.2917173074219844 1.0 0.1762218760282218 0.327507803675052 0.6363606533565179 0.871107587022149 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a77be1874a98d5834adfd01389585a5ec0e807ec --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 905, + "title": "Average number of proteins per term", + "value": 30.457458563535912 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d90f59a8ffb61e91e0ca8561db66e76296b5ce8e --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b571bb2c40779b3bc1a85bee93be65117db4185a --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,297 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome complex 0.6571539392850979 4.255511612210252 2.0857153863129696e-05 0.0186988865438935 0.0032174834044603 46 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,P04792,O75832,P61289,Q15386,Q9UL46,P28066,P54727,P28072,P54725,P49720,P25786,O43242 30 +Endopeptidase complex 0.6116820348454898 4.065990790316344 4.782882456089155e-05 0.0423626496728814 0.0061835837468011 53 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,P04792,Q9H490,O75832,P61289,Q15386,Q9UL46,P28066,P54727,P28072,P54725,P49720,P25786,O43242 31 +Peptidase complex 0.5611106363089652 3.8645444346331166 0.0001112967286387 0.095822099112664 0.0125904424272579 61 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,P04792,Q9H490,O75832,P61289,Q15386,Q9UL46,P28066,P54727,P28072,P54725,P49720,P25786,O43242 31 +Proteasome core complex 0.8684718995584977 3.5109133503505836 0.0004465699351419 0.3325134627719656 0.0310881377925719 14 P25788,P25789,P20618,Q99436,P49721,P28072,P28070,P60900,P28074,P28066,P49720,P25786 12 +Ficolin 1 rich granule lumen 0.4822477313215241 3.310509349112453 0.000931263412212 0.5696627447542071 0.0495760816501125 72 P15586,O75874,P51665,Q9UNM6,Q13200,P35573,Q15008,P09429,Q16539,P20618,Q96G03,O00232,P14618,P14174,P17980,Q9BU76,P46976,P04080,P06744,P08238,P53396,P06737,Q13442,Q99436,P25787,P36871,O00231,Q9NZ32,Q7Z6Z7,P22392,P28066,P00491,P18669,Q86VP6,P09960,P08236,P07900,O43242 38 +Microtubule 0.3609964450349688 3.040281392784195 0.0023635720608801 0.8825290939764683 0.0737597487964312 142 Q15018,Q15691,P98170,Q9H6D7,P36507,Q6NUK4,Q9Y266,Q14203,Q07866,P16949,Q96CS2,Q6SZW1,Q9BVA1,Q5SW79,Q9HC35,Q9Y496,Q9NZZ3,Q15813,P78371,Q86VS8,Q9H6U6,Q9P258,P13693,P07437,Q9UQB8,Q16555,P78559,Q9Y6G9,O94967,Q96AQ6,Q14152,O43670,Q86TI2,P36405,Q15814,Q9BUF5,Q02790,Q99426,O43237,Q00535,Q9HD42,P46821,Q15555,O95999,Q9NUL3,Q9NQT8,Q9BXS6,Q13409,P43034,O75122,O14965,P0DP25,Q7Z460,O94927,P04350 55 +Proteasome core complex beta subunit complex 0.9438267992978314 3.0153029456467166 0.0025672269554928 0.9023463046650776 0.0774446798240337 7 P20618,P49721,P28072,P28070,P28074,P49720 6 +Early endosome membrane 0.496864584513897 2.911619912919281 0.0035955986602742 0.9616070303305508 0.0804771400470225 46 Q99961,Q9UJY5,O14964,Q96T51,O60493,Q96J02,Q15075,P61020,P04083,Q9P258,Q9UNH7,Q13596,Q9H223,O75165,Q86YV9,P04439,Q92783,Q01968,Q9Y5X3,Q8NB49,Q8TDB6,Q96L92,Q13614,Q9UMY4,Q9H267,Q8IV08,Q7Z3T8,P62330,O60749,Q9UL25,Q9H4M9 31 +Axon 0.3440341286610201 2.7880722676090977 0.005302271429751 0.9918629080309638 0.0974487296602437 139 Q16658,Q96A49,Q99497,Q99720,P51114,P04350,Q12955,P07900,Q13131,P42224,Q12756,Q14203,Q07866,Q16512,Q15075,Q6SZW1,Q9UPT5,Q9Y496,P27695,Q9Y2J2,P78559,Q5T1M5,Q13740,Q92572,P42858,P08238,P07197,P53621,P49841,O75150,Q93008,P04792,O00203,Q14195,Q9NZ32,Q9UBB6,Q02790,Q9UKA9,O14617,Q00535,P46940,Q13614,P46821,P35613,Q9UBF2,Q9NUL3,Q9NQT8,P43034,P38935,P07196,Q9P265,Q6IBS0,O14965,Q9UL25,P0DP25,Q7Z460,Q9Y5K6 57 +Cytosolic ribosome 0.4310379633827251 2.7699349258353454 0.0056067493189604 0.9938320339915228 0.0974487296602437 78 P46778,P46783,P05386,P27635,P62917,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62241,P08865,P84098,P62899,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P26373 34 +Proteasome accessory complex 0.6535942407586873 2.769365253809457 0.0056165631108264 0.993886878524135 0.0974487296602437 20 P62195,P62191,P62333,P51665,O00231,Q9UNM6,O00232,Q9UL46,P43686,Q13200,Q15008,P61289,Q99460,P17980,P48556,O43242 16 +Ficolin 1 rich granule 0.4207439344330424 2.7117025227145968 0.0066938635947595 0.9977079599925084 0.1044473543665066 88 P17931,O75874,P15586,P51665,Q9UNM6,Q5T4S7,Q13200,P35573,Q15008,P09429,Q16539,P20618,Q96G03,O00232,Q9Y6G9,P14618,P14174,P17980,Q9BU76,P46976,P04080,P06744,P08238,P53396,Q13442,P06737,Q99436,P25787,P36871,P42785,O00231,Q9NZ32,Q7Z6Z7,P22392,P28066,P00491,P18669,Q86VP6,P09960,P08236,P07900,O43242 42 +Cytosolic small ribosomal subunit 0.5172533208470604 2.676798970435583 0.0074329217866464 0.9988313647461042 0.105550789344305 32 P61247,P08865,P62241,P62081,P46783,P62841,P62847,P39019,P46781,P62753,P62277,P15880,P62269,P62266,P23396,P08708 16 +Proteasome regulatory particle 0.6599621937565152 2.675779928213091 0.0074555583121251 0.998855237816015 0.105550789344305 17 P62195,P62191,P62333,P51665,O00231,Q9UNM6,O00232,Q13200,Q15008,Q99460,P17980,P48556,O43242 13 +Proteasome core complex alpha subunit complex 0.8626434325729313 2.66950152293713 0.0075963928629572 0.9989932018487128 0.105550789344305 7 P25788,P25789,P60900,P25786,P28066 5 +Site of polarized growth 0.4415597617321728 2.49514012852479 0.0125907397280924 0.9999895296243896 0.1424327431740457 52 Q16658,Q96A49,Q99720,P51114,Q07866,Q06787,Q9UPT5,Q8WX93,P27695,Q5T1M5,P08238,P53621,Q93008,Q14195,Q9UKA9,Q02790,Q00535,P46940,P46821,Q8IYI6,Q9UBF2,P43034,P38935,P07196,Q6IBS0,Q14247,P0DP25,P07900 28 +9plus0 non motile cilium 0.6913054005920227 2.417080746447958 0.0156455459938118 0.9999993659591944 0.160236899448406 12 P46821,Q15051,Q15555,P41208,Q15814,Q01968 6 +Retromer complex 0.7140204356730009 2.3909442248951165 0.0168051056032676 0.9999997818017526 0.1635335545264217 10 Q5VZ89,O75436,O60493,Q9UNH7,O60749,Q13596,Q9Y5X3 7 +Magnesium dependent protein serine threonine phosphatase complex 0.7214851080194419 2.3605346108598524 0.0182486153812928 0.9999999422731554 0.1738420728428424 9 P63151,P30154,P30153,Q8TF05,Q9NY27,Q14738 6 +Distal axon 0.4108131038614013 2.323467106203711 0.0201540727509297 0.9999999900504924 0.182394358395914 59 Q16658,Q96A49,Q99720,P51114,Q07866,Q06787,Q9UPT5,Q8WX93,P27695,Q5T1M5,P08238,P53621,O75150,Q93008,Q14195,Q9UKA9,Q02790,O14617,Q00535,P46940,P46821,Q8IYI6,Q9UBF2,P43034,P38935,P07196,Q6IBS0,Q14247,P0DP25,P07900 30 +Ciliary transition zone 0.725704025221315 2.267692858510082 0.0233479334356179 0.999999999481695 0.2029554261019681 8 A6NIH7,Q15555,P41208,Q15814,Q15051,Q15019 6 +Dynein complex 0.6741700838124225 2.2563082221293236 0.0240513348255286 0.99999999972997 0.2034248412813407 11 Q9UJW0,Q14203,Q9Y6G9,Q8IVD9,O43237 5 +Cytoplasmic dynein complex 0.6911181949532132 2.209406459914778 0.027146382115545 0.99999999998476 0.2193524626300742 9 Q8IVD9,Q9UJW0,O43237,Q9Y6G9 4 +Cytosolic region 0.7573297522413699 2.198416414709754 0.0279194450087203 0.9999999999925776 0.2236026348043532 7 Q9UQB8,Q13526 2 +Postsynaptic cytosol 0.7973973020787772 2.1695018106339883 0.0300446070465472 0.999999999998976 0.2257662851266018 6 Q9UQB8,Q13526 2 +Podosome 0.6263593911840758 2.155062430975926 0.0311569491152932 0.9999999999996376 0.2269682107378697 13 Q99961,P61978,Q16658,P67936,Q8WX93,P18206,Q14247,A1X283 8 +Photoreceptor connecting cilium 0.7923246924315106 2.147337932366934 0.031766388047187 0.9999999999997948 0.2269682107378697 6 P41208,Q15051,Q15814,Q15555 4 +Neuron to neuron synapse 0.3741670592852732 2.117250523017183 0.034238591568841 0.9999999999999796 0.2365337814488634 67 Q99720,P51114,P62917,P25685,P62269,Q14012,Q9UQB8,P23396,O43815,Q14152,P39019,Q13177,P40818,Q00535,P46821,Q13614,P52294,Q96HC4,P62277 19 +Cop9 signalosome 0.6526905900405575 2.0776714402919016 0.0377396312493369 0.9999999999999992 0.2529953057825924 10 Q9UBW8,Q92905,Q7L5N1,Q9UNS2 4 +Centriole 0.4865776442827302 2.043757439732754 0.0409775156075373 1.0 0.2667960548548296 27 Q5SW79,Q9Y496,P41208,Q9P287,O43379,Q9BPX3,O14965,Q14203,P62826,Q15051,Q6UVJ0,P42858 12 +Spindle microtubule 0.4283795624434833 2.0329158691856173 0.0420610234817486 1.0 0.2718944732213039 37 Q15691,P98170,Q9Y496,Q9H6D7,Q9NZZ3,P36405,P43034,O75122,O14965,P0DP25,Q7Z460,O94927,Q9HD42,Q96CS2 14 +Prefoldin complex 0.8192982456140505 2.0249870114434585 0.0428686979562704 1.0 0.2751501535491118 5 Q9UHV9,Q9NQP4,O15212,Q99471 4 +Extrinsic component of endosome membrane 0.8526562435464295 2.004236134158397 0.0450447715577762 1.0 0.2830938768040796 4 P04083,P40818 2 +Vesicle lumen 0.3198284350536968 1.9718978678270176 0.0486212667628851 1.0 0.3013852494548702 125 O75874,P15586,Q9UNF1,P51665,Q9UNM6,Q13200,Q15008,Q99460,P09429,Q16539,P20618,Q96G03,P78371,O00232,P07741,P13010,P07437,Q9BRF8,P14174,P30740,P14618,P17980,P46976,P04080,P06744,P08238,P53396,P06737,P53990,Q99436,P25787,Q9NZ32,Q99439,Q9NUQ9,Q7Z6Z7,P22392,Q8NBM8,P28066,P30041,P00491,Q9UQ80,P18669,Q9NTK5,Q96RL7,Q86VP6,P08236,O43242 47 +Protein phosphatase type 2a complex 0.7510828021371416 1.965230012814787 0.0493876217407789 1.0 0.302633305094561 6 Q14738,P63151,P30153,P30154 4 +Presynaptic cytosol 0.8405166621883828 1.954598938238516 0.0506304267483126 1.0 0.3073024732051029 4 Q9UQB8 1 +Non motile cilium 0.536091792543902 1.9259087302393376 0.0541157711632158 1.0 0.3188962441607325 17 P46821,Q15555,P41208,Q01968,Q15814,Q15051 6 +Kinetochore microtubule 0.6558946840596 1.924179334014562 0.0543321085890196 1.0 0.3188962441607325 8 O75122,Q9NZZ3,Q9HD42 3 +Nuclear outer membrane 0.6276800675555331 1.8854174428083836 0.0593735008875846 1.0 0.3315853214060135 9 Q99720 1 +Polysome 0.3857761147691784 1.8795493298319883 0.0601695244920192 1.0 0.3315853214060135 48 P51114,P62917,P13639,P20290,O15372,P62701,Q6PKG0,P60900,P23396,P84098,P62899,P62906,P08670,P83731,Q04637,Q92616,P83881,P61758,Q9HAU5,P62753,Q92615,P62266,P25786 23 +Cilium 0.3513748457339682 1.8760045917890396 0.0606546493776936 1.0 0.3315853214060135 92 Q15691,Q99570,P28070,P15311,Q14203,P62826,Q13526,Q92973,P48729,Q9UPT5,Q5SW79,Q9Y496,P04083,P14618,P17612,A0AVF1,Q15019,O43924,O95721,P06744,P41208,Q8NEB9,Q15814,Q9NUQ9,Q01968,A6NIH7,Q15051,P46821,Q15555,Q96RL7,Q86Y56,P21266,P43034,O14965,P04350 35 +Proteasome regulatory particle lid subcomplex 0.6874905291286877 1.8719424164445295 0.0612145705082471 1.0 0.3315853214060135 7 Q9UNM6,O43242,P48556,O00232 4 +Proteasome regulatory particle base subcomplex 0.6382337669131996 1.835336392826304 0.0664558619535382 1.0 0.3447318199723532 8 P62195,P62191,P62333,Q13200,Q99460,P17980 6 +Photoreceptor outer segment 0.6789710016819778 1.831393918975326 0.0670417683040156 1.0 0.3447318199723532 7 Q01968,Q15051,Q15555 3 +Amphisome membrane 0.767106740274994 1.803657189655068 0.0712850646686438 1.0 0.3525299646181566 5 Q9HD42 1 +Amphisome 0.767106740274994 1.803657189655068 0.0712850646686438 1.0 0.3525299646181566 5 Q9HD42 1 +Tubular endosome 0.7917709932834897 1.753174871125537 0.0795719949955431 1.0 0.3787708279130494 4 Q9Y5X3,Q9UNH7 2 +Axon initial segment 0.9088518843120076 1.7510373382976403 0.0799394785982237 1.0 0.3787708279130494 2 Q12955 1 +Transcription elongation factor complex 0.4824268655157561 1.7484322004419002 0.0803892161620813 1.0 0.378917919930644 22 P18615,P55199,Q08945,Q92541,Q9Y5B9,Q14241,Q8IXH7,Q9GZS3,Q6IA86,Q9NYV4,Q15370,Q659A1,Q8WX92 13 +Chaperone complex 0.4542187653306718 1.7407811287335813 0.0817219510739462 1.0 0.3812286892882541 26 P08238,P31948,Q16543,Q969U7,O95817,O95456,P53041,Q8WXX5 8 +Cytosolic large ribosomal subunit 0.3699399820755072 1.6989459120661343 0.0893293752284873 1.0 0.4062466561898546 46 P61513,P46778,P84098,P62899,P05387,P62906,P27635,P39023,P62917,P83731,P18621,P32969,P83881,P05388,P62750,P26373 16 +Tertiary granule lumen 0.5024193090626872 1.6842794183717993 0.0921276810736453 1.0 0.4083052034459428 16 O75874 1 +Eukaryotic translation initiation factor 4f complex 0.6025939451739099 1.6539023497654737 0.0981473551535376 1.0 0.4113723925349207 8 P23588,P06730,Q15056,Q04637,P78344,P60842 6 +Multivesicular body membrane 0.6805702318375884 1.6465734906278904 0.0996457430108215 1.0 0.4113723925349207 6 Q9HD42 1 +Eukaryotic translation initiation factor 2b complex 0.6801601190301303 1.644696330476516 0.1000324499429137 1.0 0.4113723925349207 6 P49770,Q9NR50,Q14232 3 +Cyclin dependent protein kinase holoenzyme complex 0.5363056715708079 1.644383821909628 0.1000969447368276 1.0 0.4113723925349207 13 Q00534,Q9P287,P49736,O95067,Q9NYV4,P24941,P06493,Q00535 8 +Phagocytic cup 0.7635374067683905 1.635132661203368 0.1020212406657603 1.0 0.4113723925349207 4 P04083 1 +Ribose phosphate diphosphokinase complex 0.7617655656240923 1.6276957311914342 0.1035894187151611 1.0 0.4113723925349207 4 P11908,Q14558,P60891 3 +Tor complex 0.759684225756811 1.6189557229032938 0.105456790130499 1.0 0.4113723925349207 4 Q9Y4R8,Q96Q15 2 +Torc1 complex 0.759684225756811 1.6189557229032938 0.105456790130499 1.0 0.4113723925349207 4 Q9Y4R8,Q96Q15 2 +Scf ubiquitin ligase complex 0.5927101510933929 1.6031251583071773 0.1089070246157795 1.0 0.4222876034157012 8 Q9HB71,Q93034,Q96K76,Q13309 4 +Axon cytoplasm 0.435543298364355 1.6000070887411784 0.1095970108298574 1.0 0.4222876034157012 26 Q9Y496,P27695,P04792,O00203,P43034,Q12756,Q9NZ32,P07196,P78559,Q9UL25,O14617,Q92572 12 +Extrinsic component of organelle membrane 0.5156565377636875 1.599562238803561 0.1096957310886317 1.0 0.4222876034157012 14 Q6SZW1,P04083,P62942,P40818 4 +P body 0.381566977258974 1.5926404879981455 0.1112408651840386 1.0 0.4233159701817959 36 P19474,P25789,P25787,Q96C86,Q9HCE1,Q5T6F2,Q7Z739,P60900,Q93062,Q9NPI6 10 +Trna methyltransferase complex 0.7518333091956566 1.5859502610485368 0.1127505930246122 1.0 0.4233995298227139 4 Q9UBP6 1 +Post mrna release spliceosomal complex 0.6185885119512167 1.5401209491723398 0.1235308741947451 1.0 0.448977675286122 7 Q9ULR0 1 +Mll3 4 complex 0.7367516020904203 1.522393209002085 0.1279105854066331 1.0 0.4611915529601713 4 Q9UBL3 1 +Multivesicular body 0.5119420942505186 1.5025539872464106 0.1329540962990782 1.0 0.475586787156782 13 Q9HD42,Q96PU5 2 +Microbody 0.3229846892360677 1.4920476900079205 0.1356866436586856 1.0 0.4796734863715254 66 P48735,P34913,O75874 3 +Microtubule associated complex 0.3416443766179676 1.4835947077745244 0.1379164742324703 1.0 0.4841665692755384 53 Q9H6D7,Q14203,Q07866,Q96CS2,Q9Y496,Q9Y6G9,P78559,O95793,P61163,Q9NZ32,Q8IVD9,O43237,P46821,Q15555,Q9UJW0,Q13409,P43034,O14965,O94927 19 +Ciliary basal body 0.4626287824177339 1.4811076103647425 0.1385779002171605 1.0 0.4841665692755384 18 Q15691,P41208,P28070,P15311,Q13526,A0AVF1 6 +Intracellular protein containing complex 0.3244108213840654 1.478638485297605 0.1392369611374997 1.0 0.4841665692755384 253 P30153,P49721,P28070,Q13200,Q15370,Q96K76,Q9HC52,P20618,Q96T76,Q9NR50,Q14738,Q07864,P49642,Q5VZE5,P04792,Q9NQG5,O75832,P46934,Q9NT62,Q96Q15,P54727,P28072,Q86VP6,Q13309,P49720,Q9UBU6,Q9NVU0,Q93034,O95155,O95251,Q9GZS3,P28074,P49643,P30154,Q8TF05,Q9BXJ9,Q9NY27,P60900,Q9NZL9,Q9H9T3,Q9Y4R8,O75448,P25788,P08238,Q99436,O00170,P68036,P61289,P28066,Q15257,Q9NXF7,Q9Y4B6,P29083,P51665,P42345,O43617,Q6NTF9,Q15008,Q99460,P48556,P62333,Q16763,P63208,O00232,Q96P16,Q9NXV2,P13010,P17612,P17980,P62195,P25789,Q8IUR0,Q9HB71,Q15386,P63151,Q9UBV2,P25205,P23193,P54725,P19784,P13984,P25786,O43242,P62191,Q92541,Q9UNM6,Q7Z569,Q7Z392,Q9Y296,Q9GZZ1,P18074,P06730,A5YKK6,O95163,P25787,O75150,Q9NZJ0,Q9UL46,Q96GG9,P41227 100 +Protein kinase complex 0.4054202627471567 1.4765499286072292 0.1397963221425675 1.0 0.4841665692755384 28 P18074,Q00534,Q96T76,P12004,P11802,P49736,Q9P287,O95067,Q13131,P06493,O15111,P24941,P13010,Q9NYV4,P78527,Q00535 16 +Elongin complex 0.8428279287174992 1.475167341605121 0.1401675592819791 1.0 0.4841665692755384 2 Q14241 1 +Trapp complex 0.6812597952037207 1.431523358433716 0.1522802773801275 1.0 0.5049518697291265 5 O43617,Q8IUR0 2 +Cdc73 paf1 complex 0.6812261116677004 1.4313759484831132 0.152322497719394 1.0 0.5049518697291265 5 Q9GZS3 1 +Contractile fiber 0.3342396125635458 1.4170060021209514 0.156481172641669 1.0 0.5071519064997663 54 P62942,P51114,P67936,P0DP25,Q9UJW0,Q16527,O95817,Q96AC1,Q12955,P60900,P04792,Q96HC4,Q6IBS0,Q16512 14 +Eukaryotic translation initiation factor 3 complex 0.4845331719530255 1.412286793872202 0.1578655332831848 1.0 0.5071519064997663 14 O75821,O15371,Q14152,Q9Y262,Q9UBQ5,O75822,P55884,Q92905 8 +Autophagosome 0.3753384796049725 1.4117293944154063 0.1580296548430211 1.0 0.5071519064997663 31 P19474,O95721,Q9NZZ3,Q9HD42,Q13137,P42858 6 +Haus complex 0.6683869370785447 1.375142548305774 0.1690872555619544 1.0 0.5240546790533178 5 Q9H6D7,Q96CS2 2 +Autophagosome membrane 0.4780178130608408 1.3728893445603594 0.1697867496161154 1.0 0.5244266498381721 14 Q9NZZ3,Q13137,Q9HD42 3 +Chaperonin containing t complex 0.546551328193488 1.363931884570491 0.1725890046517295 1.0 0.5294679634231025 8 P17987,P50991,P78371,P40227,P48643,P49368 6 +Basal cortex 0.8144902132632283 1.3564996497583215 0.1749402467318686 1.0 0.5318499043792683 2 O75122 1 +Centriolar subdistal appendage 0.8252235375484944 1.3542954198331538 0.1756421468168088 1.0 0.5318499043792683 3 Q5SW79 1 +N terminal protein acetyltransferase complex 0.6630481979741631 1.3517381794105867 0.176459086806215 1.0 0.5318499043792683 5 P41227,Q9BXJ9,Q5VZE5 3 +Cul5 ring ubiquitin ligase complex 0.8130295062810409 1.350388133648231 0.1768915151581875 1.0 0.5318499043792683 2 Q15370 1 +Phosphatidylinositol 3 kinase complex class iii 0.8115687992988674 1.3442775199031376 0.1788586621394421 1.0 0.535983739192699 2 Q8NEB9 1 +Polymeric cytoskeletal fiber 0.2941434634661902 1.3396367824058153 0.180363459379975 1.0 0.5363531709924958 196 Q15018,Q15691,Q12756,Q14203,Q96CS2,Q8IX90,Q9BVA1,Q9HC35,Q16352,P04083,P06753,P07437,Q9UQB8,Q96AQ6,Q14152,Q00535,Q9HD42,P43034,P0DP25,Q7Z460,P98170,P36507,P15311,P16949,Q6SZW1,P48729,Q5SW79,Q9NZZ3,Q9H6U6,Q9P258,Q16555,O94967,Q86TI2,O43237,Q15555,Q13409,O75122,O14965,O94927,P04350,Q6NUK4,Q9Y266,Q07866,Q16512,Q9Y496,Q15813,P78371,Q86VS8,P13693,P78559,P48681,P67936,P36405,Q15814,Q02790,Q99426,P46821,Q9NUL3,Q9NQT8,Q9BXS6,P07196,P06493,Q9H6D7,Q9UHD8,Q9Y6G9,P07197,O43670,P23258,Q9BUF5,Q14195,Q14019,P46940,O95999,Q9BSJ2,Q96HC4,Q9NZQ3,Q6IBS0,Q9Y5K6 78 +Main axon 0.50538603667555 1.3394445456997308 0.1804259959502574 1.0 0.5363531709924958 11 P46821,P78559,Q12955,Q9Y2J2 4 +Set1c compass complex 0.5734695232208783 1.319134782821542 0.1871240565655003 1.0 0.5497022019069828 7 Q9UBL3 1 +I band 0.3565779947803059 1.314827584943411 0.1885678544249189 1.0 0.5497022019069828 32 P62942,O95817,Q16527,P04792,Q12955,Q16512 6 +Dynactin complex 0.6543817428084853 1.313728082171739 0.1889377271288235 1.0 0.5497022019069828 5 Q9UJW0,P61163,Q9NZ32 3 +Mitotic spindle microtubule 0.5356839341621564 1.3072707826942 0.1911207634276968 1.0 0.5508416907709096 8 Q9H6D7,O94927,Q96CS2 3 +Microtubule organizing center 0.3030574016414624 1.3014019785821245 0.1931208967533617 1.0 0.5542984377325266 221 Q15018,Q15691,O75351,P28070,Q14203,Q96CS2,Q96T76,Q9HC35,Q15004,O60271,P41208,Q9BPX3,P04150,Q9HD42,O60763,Q6DKK2,Q86UY6,O95067,P43034,Q15051,Q6UVJ0,P0DP25,Q7Z460,Q99504,P15311,P28074,P24941,P62826,Q13526,Q9H814,P48729,Q5SW79,Q9NY27,Q14674,Q8TD16,P42858,P53990,Q12873,P61163,O43379,Q9Y3D8,O43237,Q9Y5A9,P62081,Q15555,Q9NTK5,Q13409,O75122,O14965,O94927,Q9UN37,Q16512,Q9UNN8,Q9UPT5,Q9Y496,P27695,P63208,Q86VS8,P17612,A0AVF1,O95721,P36405,Q8WVJ2,Q9UFC0,Q9UJW0,Q9P287,P25205,P54725,P25786,P06493,Q9H6D7,Q3YEC7,Q5T4S7,Q00534,Q02750,Q9Y6G9,Q96CT7,P49841,Q9NZJ0 79 +Actomyosin 0.3755995592708736 1.2924357627444956 0.1962062784355278 1.0 0.5548958812004772 29 Q16658,P67936,Q15942,Q9UJW0,O95817,Q96AC1,Q96HC4,Q9UHD8,Q99439,P06753,Q9UHB6 11 +Ap type membrane coat adaptor complex 0.4913152064792696 1.2606023482501547 0.2074521521838104 1.0 0.5727165091507844 11 O00203,O14617 2 +Aryl hydrocarbon receptor complex 0.7893660531697322 1.2515486879233662 0.2107343619306201 1.0 0.5727165091507844 2 P08238 1 +Centrosome 0.2774894143220976 1.2428687859000445 0.2139161897432622 1.0 0.579623208735486 174 Q15018,Q15691,Q9UN37,Q99504,O75351,Q9H6D7,Q3YEC7,Q5T4S7,P28074,Q14203,P24941,Q9H814,Q96CS2,P48729,Q00534,Q9UNN8,Q9UPT5,Q5SW79,Q9Y496,P27695,Q15004,Q9NY27,P63208,Q86VS8,O60271,Q14674,Q9Y6G9,P17612,Q8TD16,A0AVF1,O95721,P53990,P41208,P49841,Q12873,P61163,O43379,Q9Y3D8,Q9NZJ0,O43237,Q9Y5A9,Q6DKK2,P62081,Q86UY6,Q9NTK5,Q9UJW0,Q9P287,O95067,P43034,Q13409,P25786,O14965,P54725,Q15051,Q6UVJ0,P0DP25,Q7Z460,O94927 58 +Neuron spine 0.3397713563452298 1.2391108958806032 0.2153044324497466 1.0 0.5799122362113711 38 P46821,O43815,Q13614,P51114,P25685,P40818,Q9Y4F1,Q9UQB8,P46934 9 +Alpha dna polymerase primase complex 0.6674576252154787 1.228915993288957 0.2191033044100392 1.0 0.5832014426208397 4 P49643,P49642 2 +Condensin complex 0.5523698069046035 1.2153584299654676 0.2242294155851227 1.0 0.5890589341115167 7 Q15021,P42695,Q15003,Q9BPX3,O95347,Q9NTJ3 6 +Nuclear replication fork 0.4233978630875263 1.198361478665564 0.2307763221660823 1.0 0.5890589341115167 17 P28340,Q9H4L7,P49642,Q7L590,P35244,P12004,P15927,Q9UNS1,P25205,P49643 10 +Trans golgi network membrane 0.3827063499821166 1.1976140169160054 0.2310673166956778 1.0 0.5890589341115167 26 P83436,Q7Z6M1,Q9UP83,Q9UID3,P20645 5 +Microbody lumen 0.397054825788066 1.1806353507103549 0.2377476139801051 1.0 0.6010100297541764 23 P34913,O75874 2 +Vesicle tethering complex 0.3584713257024342 1.1526050537200203 0.2490725279738237 1.0 0.6141979232052056 29 P83436,Q7Z392,Q9UPT5,Q9H267,Q8IYI6,O43617,Q96KP1,Q8IUR0,Q9UP83,Q9UID3,Q9Y296,Q9H9E3,A2RRP1 13 +Cytoplasmic stress granule 0.311006298700097 1.1230394765025016 0.2614207288774004 1.0 0.6258619510983714 49 P26196,Q13464,Q93062,P67809,Q06787,Q13310,P61978,Q6PKG0,Q14258,Q14011,Q71RC2,Q9UN86,O95793,P06730,Q14157,Q04637,P11940,Q92879,Q8WWM7,Q9Y5A9,Q9HCE1,Q9NUL3,Q92615,Q7Z739,Q6Y7W6,Q13283 26 +Nucleolar ribonuclease p complex 0.7499269646508899 1.0880872342010388 0.2765565987774727 1.0 0.636854254182221 2 Q99575 1 +Ribonuclease mrp complex 0.7499269646508899 1.0880872342010388 0.2765565987774727 1.0 0.636854254182221 2 Q99575 1 +Multimeric ribonuclease p complex 0.7499269646508899 1.0880872342010388 0.2765565987774727 1.0 0.636854254182221 2 Q99575 1 +F actin capping protein complex 0.5571804621234218 1.0755552848015644 0.2821261945474183 1.0 0.6431340203159032 6 P58546,P52907,P47755,Q9BPX3,P47756 5 +Translation preinitiation complex 0.416333551169561 1.0630165196035524 0.2877744598815361 1.0 0.6509096157064761 15 O75821,P05198,Q14152,O15371,P60228,Q9Y262,Q9UBQ5,O75822,O15372,P55884,O00303 11 +Actin filament bundle 0.3408467349044833 1.0603823804310573 0.2889706747100624 1.0 0.6509096157064761 30 Q16658,P67936,Q15942,Q8WX93,Q9UJW0,O95817,Q96AC1,Q96HC4,Q9UHD8,Q99439,P06753,Q9UHB6 12 +Costamere 0.5199853574058169 1.056370395456101 0.2907990258855886 1.0 0.6530350333162722 7 P51114 1 +Signal recognition particle 0.5933900912667148 1.0467850811973256 0.2951987126348527 1.0 0.6591505618991365 5 Q9UHB9,O76094,P49458 3 +Origin recognition complex 0.5502875585578114 1.0437104006380802 0.2966193963944343 1.0 0.6595591000908184 6 Q9UBD5,P49736,Q9UFC0 3 +Phosphatase complex 0.4022513793242759 1.0414372277387287 0.2976726722770542 1.0 0.660278844143956 16 P63151,P30153,P30154,Q8TF05,Q9NY27,Q14738 6 +Transcription preinitiation complex 0.739953665191536 1.0240533121127555 0.3058100947349493 1.0 0.6701165514167776 3 P29083 1 +Nucleotide excision repair complex 0.5381838250002997 0.9879755937752304 0.3231646012527334 1.0 0.6914041705288977 6 P41208 1 +Ekc keops complex 0.7248028045574146 0.9853909105720838 0.3244320926488759 1.0 0.6924788769981904 2 Q9NPF4 1 +Dna replication preinitiation complex 0.4325133292444439 0.9801180743363584 0.3270278382938671 1.0 0.6963769262492936 12 Q9Y248,Q9BRT9,P49736,Q9UBD5,P25205,P33991 6 +Intercellular bridge 0.3726603092449064 0.9784122057829736 0.3278704937902161 1.0 0.6965323870425953 22 O75937,P28161,P21266,Q15051,Q15019 5 +Replisome 0.4397318598553791 0.9725085897814492 0.330797593661793 1.0 0.6985886802992941 11 P28340,P49642,P35244,P12004,P25205,P15927,P49643 7 +Rpap3 r2tp prefoldin like complex 0.5025901310743427 0.971521575506403 0.3312886144606362 1.0 0.6985886802992941 7 Q9UHV9 1 +Zona pellucida receptor complex 0.575620530530217 0.9697582724630864 0.3321669966261535 1.0 0.6985886802992941 5 P17987,P78371,P49368 3 +Neuron projection cytoplasm 0.3116179526429897 0.9670512311248368 0.3335184235678898 1.0 0.6985886802992941 37 Q9Y496,P27695,P04792,O00203,P43034,P07196,Q9NZ32,Q9UQB8,P78559,O14617,Q92572 11 +Microtubule end 0.4299419557527166 0.9656049911153944 0.3342418768724799 1.0 0.6985886802992941 12 Q15018,Q15691,Q15555,Q14203 4 +Nata complex 0.7220923436586812 0.9560849297907574 0.3390293279173795 1.0 0.7033374624879108 3 P41227,Q9BXJ9 2 +Membrane coat 0.3014313549227764 0.9538752741913412 0.3401467807044067 1.0 0.7033374624879108 43 P35606,Q9UBC2,P48444,P53621,Q9NR31,Q15437,Q9UBF2,P61923,Q9Y678,O00203,O95486,O95487,Q15436,Q14677,O14617,Q92572 16 +Elongator holoenzyme complex 0.571345029239752 0.9513192659689944 0.3414423297724607 1.0 0.7033374624879108 5 Q6IA86,O95163,Q0PNE2,Q9H9T3 4 +Transcription factor tfiih holo complex 0.7186118468642471 0.9429213942405584 0.3457211109311431 1.0 0.705987528191982 3 Q96T76 1 +Ciliary membrane 0.4945211693575848 0.9323905521790103 0.3511347256126993 1.0 0.7098330176581612 7 P06744,O95721 2 +Death inducing signaling complex 0.5946943258488988 0.9232978791051324 0.355851992848192 1.0 0.7150641130531832 4 Q13546,Q9UNN5 2 +Nucleocytoplasmic transport complex 0.4538005447134648 0.8821183204730759 0.3777128259421665 1.0 0.7365209480125361 8 P52294,Q9HAV4,O60684,P62826 4 +Filopodium 0.306181220489108 0.874669826411744 0.3817535824050115 1.0 0.7365209480125361 32 Q16658,P26038,P51114,Q00535,P15311,O15357,P35241,P62330,Q9Y4F1,Q9H4L5,Q9UQB8,Q6IBS0,Q8N8S7,Q12792,Q14204,Q06787 16 +Cytoplasmic region 0.2705094722790567 0.8744424765212377 0.3818773337926315 1.0 0.7365209480125361 66 Q99570,Q12756,Q14203,Q9Y496,P27695,Q9UHD8,Q9UQB8,P17612,P78559,Q13363,Q15019,Q92572,Q14204,Q8NEB9,P61163,P04792,O00203,Q9NZ32,O14617,Q15555,Q9NUL3,P43034,P09497,P07196,O75122,Q9UL25,Q7Z460,P04350 28 +Chromaffin granule membrane 0.6970493718959996 0.8739546952953304 0.3821429265262814 1.0 0.7365209480125361 2 P30626 1 +Chromaffin granule 0.6970493718959996 0.8739546952953304 0.3821429265262814 1.0 0.7365209480125361 2 P30626 1 +Ruffle 0.2763528537041793 0.8717905814244148 0.38332263371162 1.0 0.7365209480125361 61 Q16658,Q13325,O60610,P15311,Q16512,Q12792,Q00534,P50570,Q8WX93,Q9UNF0,Q9UQB8,P23396,P15531,P31751,Q9BPX3,P23528,P12814,P22392,Q8NCE2,Q9Y5X3,P46940,Q9Y217,P62330,Q14247,O75122,Q9UHB6,Q9Y5K6 27 +Immunological synapse 0.3848787182279406 0.8691838619918046 0.3847465728690638 1.0 0.7365209480125361 15 Q96L92,O95999,P15311,P51452,Q13740 5 +Neuronal dense core vesicle 0.695004382120965 0.8658475150655263 0.3865737884569356 1.0 0.7365209480125361 2 Q96RL7 1 +Cell division site 0.3473552141599392 0.8599557477123493 0.3898134364436951 1.0 0.7386235014960527 24 Q9BSJ2,Q9UHD8,P62330,P35241,P11233,Q9UL25,Q16512,Q15019,Q9UHB6,O75935 10 +Cleavage furrow 0.365236550197601 0.8585062074002269 0.3906130043359606 1.0 0.7386235014960527 19 P62330,P35241,P11233,Q9UL25,Q16512,Q15019,Q9UHB6,O75935 8 +Neurofilament 0.5488304093567237 0.8550124473725308 0.3925442568581543 1.0 0.7401094842846452 5 Q16352,P07197,P07196,O14786 4 +Supramolecular polymer 0.2829837266512677 0.8416855533556841 0.3999639867949742 1.0 0.7516545798708454 237 Q15018,Q15691,P62942,O75190,P98170,P51114,Q9H6D7,P36507,Q12955,P15311,Q6NUK4,Q9Y266,Q14203,Q07866,P16949,Q16512,Q96CS2,Q6SZW1,P48729,Q9BVA1,Q5SW79,Q9HC35,Q9Y496,Q9NZZ3,P04083,Q15813,P78371,Q16527,Q86VS8,Q9H6U6,Q96AC1,P60900,Q9P258,P06753,P07437,Q9UQB8,Q16555,P13693,P78559,P30626,Q9Y6G9,O94967,Q96AQ6,Q14152,P48681,O43670,Q86TI2,P67936,P36405,Q15814,O95817,P04792,Q9BUF5,Q02790,Q99426,O43237,Q00535,Q9HD42,P46821,Q15555,O95999,Q9NUL3,Q9UJW0,Q9NQT8,Q13409,P43034,Q96HC4,P07196,Q6IBS0,O75122,O14965,P0DP25,Q7Z460,O94927,P04350 75 +Dna replication factor c complex 0.501944579704291 0.8232603609325418 0.4103599499671422 1.0 0.7594596211048337 6 P40938,P40937 2 +Female germ cell nucleus 0.6757230499561842 0.7902489569120886 0.4293823899069253 1.0 0.7754436698272834 2 O14965 1 +Schaffer collateral ca1 synapse 0.3785412249019821 0.7764593231625748 0.4374778292915029 1.0 0.7810748486351401 14 Q9UQB8,P35080,P07196,Q9BVA1 4 +Mcm complex 0.4910603353386935 0.7746965794222682 0.4385189727151442 1.0 0.7812198234393809 6 P33992,P25205,P33991,P49736 4 +Dendritic shaft 0.4892463225643197 0.7666551302887743 0.4432865879260061 1.0 0.7850770294971342 6 Q9UQB8 1 +Dynein axonemal particle 0.4585054479050764 0.7604790948740694 0.4469682605411784 1.0 0.7885112588494474 7 P31948,Q86Y56 2 +Escrt complex 0.4058655701641405 0.746129285573652 0.4555893200304592 1.0 0.7887861085859851 10 Q9H9H4,O14964,Q99816,Q92783,Q9HD42 5 +Pronucleus 0.5510035228756052 0.7457144506370865 0.4558399279452709 1.0 0.7887861085859851 4 O43823,P83916 2 +Cornified envelope 0.4835255010355787 0.7414021166409673 0.4584496614960147 1.0 0.7917880604081933 6 P04083 1 +Clathrin coat of coated pit 0.3963093145869985 0.7362985951537673 0.4615490009811551 1.0 0.7941099731709989 11 Q00610,Q9UBC2,Q13492,Q96CW1,P53680,P63010,P09497,O94973,P42566,O95782 10 +Perikaryon 0.3283349501795418 0.727173590925384 0.4671196220127631 1.0 0.7972180880702326 24 P46821,Q13283,Q9P265,Q9UBB6,Q00535 5 +Dendritic tree 0.249845379707856 0.7255967291437636 0.4680860268521143 1.0 0.7972180880702326 117 Q96A49,P30153,P42345,P51114,P25685,Q12955,Q16512,Q6SZW1,Q9HD26,P27695,Q9Y296,Q9Y4F1,Q9UQB8,P17612,P78559,O95793,Q13740,P42858,P08238,O43815,P49841,P40818,Q9UBB6,P46934,P98179,Q00535,Q13614,P46821,P52294,P12277,Q9NUL3,P62753,Q9P265,Q7Z460,P07900 35 +Postsynapse 0.2301979314074264 0.7253771007546888 0.4682207174111448 1.0 0.7972180880702326 134 Q96A49,Q99720,P51114,P62917,P25685,Q12955,P62269,P35080,Q13526,Q99808,Q9Y296,Q9Y4F1,Q14012,Q9UQB8,P23396,P42858,Q14152,O43815,P46109,P49841,P39019,P40818,Q9UBB6,Q15042,P46934,O14617,Q00535,Q13614,P46821,P52294,Q96HC4,P62277,P07196 33 +Centriolar satellite 0.3190324498781245 0.7229130834352399 0.4697332849209039 1.0 0.7972180880702326 26 Q9Y5A9,Q86UY6,Q12873,Q86VS8,O43379,O60271,P54725,Q6UVJ0 8 +Aminoacyl trna synthetase multienzyme complex 0.3936731107205661 0.7223286709717752 0.4700924295525639 1.0 0.7972180880702326 11 Q9P2J5,P07814,P14868,O43324,P41252,Q12904,P54136,Q15046,Q13155,P47897 10 +Ciliary tip 0.45022592875418 0.7218239589098473 0.4704027171596732 1.0 0.7972180880702326 7 Q15555 1 +Apical dendrite 0.543700672318063 0.7167949902493346 0.4735006033478233 1.0 0.8003232329552015 4 O94832,O15498,P46821 3 +Motile cilium 0.3033933052721436 0.7145487389286841 0.4748879293888874 1.0 0.8003232329552015 29 P41208,P04083,Q96RL7,Q86Y56,P21266,P43034,Q15019 7 +Golgi transport complex 0.4770333617058953 0.7129548675705139 0.4758736854578347 1.0 0.8004938389207071 6 Q9UP83 1 +Cd95 death inducing signaling complex 0.6538124452235021 0.7064853654035446 0.479886350504344 1.0 0.8042539763082062 2 Q9UNN5 1 +Ciliary plasm 0.3427067231471172 0.6825667584886957 0.4948806451371041 1.0 0.8200438426419179 17 Q15555,Q99570,Q8NEB9,O95352,Q9UHD8,P17612,Q15019,P04350 8 +Vesicle coat 0.2824621002404759 0.6817253946114484 0.4954126066992996 1.0 0.8200438426419179 33 P35606,P48444,P53621,Q9NR31,Q15437,Q9UBF2,P61923,Q9Y678,O95486,O95487,Q15436,Q14677 12 +Trna splicing ligase complex 0.4697279906405273 0.6812365187871904 0.4957218440211388 1.0 0.8200438426419179 6 Q52LJ0,Q9Y3I0,Q9Y224,Q92499,Q8NCA5 5 +Protein phosphatase 4 complex 0.6425504418578127 0.6650875953165549 0.5059944682692796 1.0 0.8325908977885419 3 Q8TF05 1 +Epsilon dna polymerase complex 0.5259141752695223 0.6475540407774077 0.517273431107711 1.0 0.8389393452481264 4 Q07864 1 +Flemming body 0.3261908397872497 0.6446983454078431 0.5191226887723213 1.0 0.8389393452481264 21 Q9UN37,P53990,Q9UPT5,O75351,Q9BPX3,P62330,P62826 7 +Annulate lamellae 0.4970359693237981 0.6410986923659102 0.5214585637445972 1.0 0.8397153028271538 5 P63241,Q9Y5L0,Q8TD16 3 +Vcp npl4 ufd1 aaa atpase complex 0.4321716147115039 0.6390661095526481 0.5227799258622683 1.0 0.8403478381977847 7 O94888,Q9UNN5 2 +Mismatch repair complex 0.5225448282596905 0.6346488188884926 0.5256574808916468 1.0 0.8434752131328729 4 P54277 1 +Neuron projection terminus 0.353059765356316 0.6317970141029275 0.5275195249963807 1.0 0.8446665873191195 14 Q9UQB8 1 +Sperm head 0.6320917765768459 0.6288804722139728 0.5294273113600791 1.0 0.8450294828586801 3 P25685 1 +Dense core granule 0.6309175920514253 0.6248543180277353 0.5320666767243312 1.0 0.8462571923295601 3 Q96RL7,Q12756 2 +Dense core granule membrane 0.6307332749050596 0.6212778629002336 0.5344168164091962 1.0 0.8470178964103724 2 Q12756 1 +Anchored component of synaptic membrane 0.6278118609407008 0.6107460619096405 0.5413677067388636 1.0 0.8505832501502111 2 Q9NQX3 1 +Microtubule plus end 0.3793936289502313 0.6104649220010425 0.5415538732608485 1.0 0.8505832501502111 10 Q15691,Q15555,Q14203 3 +Stereocilium bundle 0.4252332078253697 0.6079126111864106 0.5432454349025657 1.0 0.8505832501502111 7 Q9Y6M7,Q6IBS0 2 +Polysomal ribosome 0.3016815134997185 0.6015894930605881 0.5474474245303305 1.0 0.8527365218587764 26 P84098,P62899,P62906,P62917,P83731,P20290,P62266,P83881 8 +Prc1 complex 0.6222611744084292 0.5909069262744483 0.5545827849185287 1.0 0.8557733836161048 2 Q9HC52 1 +Spindle 0.2331833943442837 0.5848082898805184 0.5586766296215822 1.0 0.8557733836161048 164 Q15018,Q15691,Q9UN37,P98170,O75351,Q9H6D7,P33981,Q9Y266,Q14203,Q96CS2,Q16539,Q96T76,Q5SW79,Q9NZZ3,Q14674,P83916,Q9Y6G9,P23396,Q15019,O43670,O43379,P04792,P04150,Q9HD42,Q15555,Q8IWC1,Q9UJW0,Q9P287,O75122,Q15051,P0DP25 31 +Dendritic growth cone 0.6188765434865063 0.5840489522920242 0.5591873778086276 1.0 0.8557733836161048 3 P08238 1 +Dendrite terminus 0.6188765434865063 0.5840489522920242 0.5591873778086276 1.0 0.8557733836161048 3 P08238 1 +Ruffle membrane 0.2805003641540053 0.5799651265280044 0.5619381353056196 1.0 0.8557733836161048 30 P15531,Q13325,O75122,P23396,Q16512 5 +Eukaryotic translation initiation factor 2 complex 0.6168907071887775 0.5774071139591276 0.5636644696247937 1.0 0.8558999077356346 3 P20042,Q9BY44 2 +Clathrin coat 0.319830081400149 0.5589878241447339 0.576170029907459 1.0 0.868265604299698 18 O00203,Q9UBC2 2 +Axonal growth cone 0.4405540814697422 0.5582795825014204 0.5766534848717335 1.0 0.868265604299698 6 Q02790,P08238 2 +Tertiary granule 0.2587886829274253 0.5520495306707166 0.5809144186729469 1.0 0.868265604299698 42 P04080,O75874,P42785,Q5T4S7,Q99439 5 +Cis golgi network 0.3182421056696675 0.5497005973642387 0.5825247470709578 1.0 0.8685088897845417 18 P24390,O43617,Q86VS8 3 +Iron sulfur cluster assembly complex 0.6082383873794988 0.5418473067932356 0.5879236990924857 1.0 0.8751166902610189 2 O76003 1 +Transcription factor tfiid complex 0.3639584805402628 0.5346104361531664 0.5929192655931357 1.0 0.8793781113735846 10 P18074,P35269,Q12962,P29083,P23193,Q9HBM6 6 +Female pronucleus 0.6035758134559321 0.5335634816800559 0.5936435795218578 1.0 0.8793781113735846 3 P83916 1 +Transferase complex transferring phosphorus containing groups 0.2451784193798425 0.524824335358365 0.5997053127470746 1.0 0.8868191307779453 85 Q9NVU0,Q14558,Q99570,Q92541,P08237,P12004,P49736,Q9GZS3,P24941,P49643,P60891,Q00534,Q96T76,O60256,Q96P16,P13010,P18074,Q07864,P49642,Q8NEB9,Q9NQG5,P78527,Q00535,P56282,Q9P287,O95067,P25205,P29083,P23193,Q9NYV4,P13984,P11908,P06493 33 +Germ cell nucleus 0.4009489641410375 0.5023759182104678 0.6154031154910546 1.0 0.8993072398702744 7 Q15645,O14965,P62826 3 +Neuron projection 0.262128689113197 0.4890999322719363 0.6247709494116223 1.0 0.8993072398702744 240 Q96A49,Q99497,P30153,Q99720,P42345,P51114,P25685,Q12955,P07900,Q14203,Q07866,P16949,Q16512,Q15075,Q6SZW1,Q9HD26,Q9UPT5,Q9Y496,P27695,Q9Y296,Q9Y4F1,Q9Y2J2,Q9UQB8,P17612,P78559,Q9Y6M7,Q5T1M5,Q13740,O95793,P42858,Q15019,P06744,P08238,O43815,Q92572,P53621,P41208,P49841,P36405,Q15814,O95817,Q93008,P04792,O00203,P40818,Q9NZ32,Q9UBB6,Q02790,Q01968,Q9UKA9,P46934,O14617,P98179,Q00535,Q13614,P46821,P52294,Q15555,P12277,Q9UBF2,Q9NUL3,Q9NQT8,P62753,P43034,P38935,O14965,Q9P265,P07196,Q6IBS0,Q15051,P0DP25,Q7Z460,P04350 73 +Condensed chromosome centromeric region 0.2379316468161083 0.4806821875266547 0.6307423927685378 1.0 0.8993072398702744 75 P33981,Q9UEE9,Q14203,Q92674,Q9NZZ3,Q9HBM1,Q9Y6G9,Q15019,O43670,Q9BPX3,O43237,Q9HD42,Q9UJW0,Q96DY7,P42695,P43034,Q6P1K2,O75122,Q7Z460 19 +Site of double strand break 0.2565857087444943 0.4789212061705443 0.6319946841220714 1.0 0.8993072398702744 33 Q9H4L7,O60921 2 +Ctf18 rfc like complex 0.4545674469302402 0.4785842262633161 0.6322344420709727 1.0 0.8993072398702744 5 P40938 1 +Growth cone membrane 0.5892491966111708 0.4780764229056695 0.6325958122901636 1.0 0.8993072398702744 2 Q9UPT5 1 +Copi vesicle coat 0.351640749927749 0.47626165419736 0.6338879802823987 1.0 0.8993072398702744 10 P35606,P48444,P53621,P61923,Q9Y678 5 +Trans golgi network 0.2316633803099882 0.4641383147062635 0.6425486525004649 1.0 0.9033933056913892 67 Q658Y4,Q7Z6M1,Q9UP83,Q9UID3,Q4J6C6,Q9C005,O75122,Q01968,P20645 9 +Endoribonuclease complex 0.3352556672602808 0.4638771520860127 0.6427357631847248 1.0 0.9033933056913892 12 Q9UPY3,Q99575,P78346,Q15631,Q99598 5 +Neurofibrillary tangle 0.5758106923751201 0.4350043462027607 0.6635592727243687 1.0 0.9139411206425598 2 P07197 1 +Rna polymerase ii holoenzyme 0.2632309266239471 0.4276735238590564 0.6688888284688663 1.0 0.9185802576089894 29 Q96T76,Q92541,Q96P16,Q9GZS3,Q9NQG5,P29083,P23193,P13984 8 +Small ribosomal subunit 0.2376253152740189 0.4164087411412546 0.677110933218068 1.0 0.924701093091612 47 P61247,P62241,P62081,P46783,P62841,P62847,P39019,P46781,P62753,P62277,P15880,P62269,P82675,P62266,P23396,P08708 16 +Exocyst 0.3544044483464977 0.4095219538805477 0.6821566590005255 1.0 0.9248306231075064 8 Q8TAG9,Q9UPT5,Q8IYI6,Q96KP1,O60645,Q9NV70,Q96A65 7 +Cul4b ring e3 ubiquitin ligase complex 0.5628287551139531 0.4079184107162232 0.6833335757833683 1.0 0.9248306231075064 3 Q9NZJ0,Q13620 2 +Male germ cell nucleus 0.4319820533313394 0.3990738085967401 0.6898388203387973 1.0 0.9248306231075064 5 Q15645 1 +Clathrin coat of endocytic vesicle 0.4315789473684163 0.3977068976557591 0.6908462523717775 1.0 0.9248306231075064 5 P53680,P63010,Q96CW1,O94973 4 +Equatorial microtubule organizing center 0.5623721881390709 0.3938065317167654 0.6937238816946745 1.0 0.9248306231075064 2 Q9BSJ2 1 +Cd40 receptor complex 0.5578609000584365 0.3935972045750315 0.6938784454033113 1.0 0.9248306231075064 3 O15111,Q9NR28 2 +Early endosome 0.2284337175294964 0.3886258692439841 0.6975529272927741 1.0 0.9274763176508248 110 Q9UJY5,Q9UN37,O75436,P36507,O60493,Q96J02,Q8WUH2,Q15075,Q02750,P04083,Q15036,Q9P258,Q9UNF0,Q9UNH7,Q13596,P30740,Q5T1M5,P42858,P31751,Q86YV9,P40818,Q92783,Q01968,Q8NB49,Q9Y5X3,Q8TDB6,Q9HD42,Q96L92,Q13614,Q9H267,Q8IV08,O60749,O60879 33 +Myosin ii complex 0.4513300204618654 0.3832163792519895 0.701559334452956 1.0 0.9286024811297876 4 Q7Z406,P60660,P35579 3 +Ap 3 adaptor complex 0.5540189433705216 0.3826850704986315 0.7019532853667103 1.0 0.9286024811297876 3 O14617 1 +Replication fork 0.242564179610657 0.3814560713933499 0.7028648614076292 1.0 0.9286024811297876 34 P28340,Q96FZ2,Q9H4L7,P49642,P35251,Q7L590,P12004,P35244,P40938,P40937,P15927,Q9UNS1,P25205,P49643,P27694 15 +Ikappab kinase complex 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.9287303561103094 2 O15111 1 +Carboxy terminal domain protein kinase complex 0.3928924478987805 0.3749382362013659 0.7077064015527577 1.0 0.929898730573966 6 P18074,Q96T76 2 +Chromatoid body 0.5511396843950841 0.3746025851726314 0.707956050127583 1.0 0.929898730573966 3 Q08J23,P06730 2 +Septin cytoskeleton 0.4473394416324306 0.37062197533553 0.7109191120178107 1.0 0.9310879831781746 4 Q15019 1 +Microtubule cytoskeleton 0.2813977144423678 0.3668766006994161 0.7137110661932136 1.0 0.9328262866116136 386 Q15018,Q15691,P30153,O75351,P28070,Q14203,Q96CS2,Q16539,Q96T76,Q9BVA1,Q9HC35,Q15004,P31689,O60271,Q9UQB8,P07437,Q96AQ6,Q14152,P41208,Q9BPX3,P04792,P04150,Q9NZ32,Q9UHD1,Q9HD42,Q00535,O60763,Q6DKK2,Q86UY6,O95067,P43034,Q15051,Q6UVJ0,P0DP25,Q7Z460,Q99504,Q99570,P98170,P36507,P15311,P28074,P24941,Q13526,P62826,P16949,Q9H814,Q6SZW1,P48729,Q5SW79,Q9NZZ3,Q9NY27,Q9H6U6,Q14674,Q9P258,Q16555,Q8TD16,P42858,O94967,P53990,Q86TI2,Q12873,P61163,O43379,Q9Y3D8,Q8IVD9,Q8NEM2,O43237,P62081,Q9Y5A9,Q15555,Q9NTK5,Q13409,O75122,O14965,O94927,P04350,Q9UN37,P33981,Q6NUK4,Q9Y266,Q07866,Q16512,Q9UNN8,Q9UPT5,Q9Y496,Q15813,P78371,P27695,Q86VS8,P63208,P83916,P13693,P78559,P23396,A0AVF1,P17612,O95793,O95721,P36405,Q15814,Q8WVJ2,Q02790,Q99426,Q99986,Q9UFC0,P46821,Q8IWC1,Q9NUL3,Q9UJW0,Q9P287,Q9NQT8,Q9BXS6,P25205,P54725,P13984,P25786,P06493,Q9H6D7,Q3YEC7,Q5T4S7,Q00534,Q02750,Q9Y6G9,Q96CT7,Q15019,O43670,P49841,Q9BUF5,Q9NZJ0,O95999 130 +Striated muscle thin filament 0.4451661412963815 0.3638427465175044 0.715975440072933 1.0 0.9328262866116136 4 P67936 1 +Myofilament 0.4451661412963815 0.3638427465175044 0.715975440072933 1.0 0.9328262866116136 4 P67936 1 +Juxtaparanode region of axon 0.5465331744347486 0.3618446587584049 0.7174681173373652 1.0 0.9329147215378096 3 Q9Y2J2 1 +Hulc complex 0.5492258252994577 0.3554562979512985 0.7222477791503661 1.0 0.9375185985698676 2 O75150 1 +Beta catenin destruction complex 0.3623104247511527 0.3490009724816777 0.7270885794832078 1.0 0.9400216634747186 7 P49841,Q9HB71 2 +Mll1 2 complex 0.2906486918702957 0.346961223574826 0.7286204503667606 1.0 0.9401312382464384 15 Q9UBL3 1 +Sarcoplasm 0.2812077980124066 0.3404625974679686 0.733508185059996 1.0 0.9402619086109014 17 P28161,P62942,O43852 3 +Proximal dendrite 0.5433829973707399 0.3390654957741917 0.7345603907770748 1.0 0.9402788594812626 2 Q6Y7W6 1 +Sarcoplasmic reticulum lumen 0.432456143243722 0.3253667812458411 0.7449034936493626 1.0 0.9466719182427292 4 O43852 1 +Cytoplasmic side of endosome membrane 0.5354951796669725 0.3176020561344626 0.7507868142712895 1.0 0.9497083310858536 2 Q9UL25 1 +Rna polymerase complex 0.2294021709695348 0.3175504553170131 0.7508259610767847 1.0 0.9497083310858536 41 Q9NVU0,Q96T76,Q92541,P49642,Q96P16,Q9GZS3,Q9NQG5,P29083,P23193,P25205,P49643,P13984 12 +Filopodium tip 0.3758408891488627 0.3163849324449981 0.7517103522067097 1.0 0.9497083310858536 6 Q7L576,P61086,Q9H4L5,O95782,Q06787 5 +Nucleotide activated protein kinase complex 0.4055555555555417 0.3138214381124882 0.7536566610802526 1.0 0.9497083310858536 5 P13861,P54619,Q13131,P10644 4 +Cell leading edge 0.2134743277466918 0.308430469516061 0.7577547999864354 1.0 0.9498173046921384 122 Q16658,Q13325,O15144,O60610,P15311,O15357,Q16512,Q12792,Q9P2B4,Q00534,P50570,P61160,Q8WX93,Q9H6U6,Q96AC1,Q9UNF0,Q9H2G2,Q9Y2J2,Q9UQB8,Q13596,P23396,P15531,O15145,P31751,Q86TI2,P08670,Q9BPX3,P23528,P23258,P12814,P35241,O14745,Q14195,Q8N8S7,Q8NCE2,P22392,Q9Y5X3,Q00535,P46940,Q9Y217,Q8IYI6,Q9UHY1,P43034,P62330,Q14247,Q6IBS0,O60749,O75122,Q9UHB6,Q9Y5K6 50 +Cytoplasmic microtubule 0.2562953121965417 0.3039407227977535 0.7611730521820457 1.0 0.950847748937314 25 Q15691,Q15555,O95999,Q9BSJ2,P36405,Q9H6U6,Q6NUK4,P23258,P43034,P13693,O75122,Q7Z460 12 +Smn complex 0.4020467836257336 0.3032112715674911 0.7617288596459144 1.0 0.950847748937314 5 Q16637,Q9Y3F4,P57678,Q8TEQ6 4 +Extrinsic component of synaptic membrane 0.3694516103945936 0.2955856541145288 0.7675465306963698 1.0 0.952799458506911 6 P46109 1 +Actin filament 0.2282271141633348 0.2942636204268987 0.7685564692928675 1.0 0.952799458506911 37 P67936,Q8WX93,P04083,Q96HC4,P15311,Q14247,Q14195,Q14019,P06753,Q6IBS0,Q16512,Q12792,Q9Y5K6,P46940 14 +Sperm connecting piece 0.5241016652059736 0.2879919477481188 0.7733529024432331 1.0 0.9553011812179087 2 P47756 1 +Spindle pole 0.2157092280140769 0.2875260891877375 0.7737095286103732 1.0 0.9553011812179087 63 Q15018,Q16539,Q9UN37,O75351,Q9UJW0,Q9P287,O43379,Q9Y6G9,P0DP25,Q96CS2 10 +Extrinsic component of postsynaptic membrane 0.3963230775099981 0.2862856526597716 0.7746593459903057 1.0 0.9553011812179087 5 P46109 1 +Trans golgi network transport vesicle membrane 0.3956140350877265 0.2842225141836075 0.7762398628088518 1.0 0.9557783344789264 5 Q00610,O95782,P09497,O43747 4 +Dna repair complex 0.2644950116211336 0.2771944005068508 0.7816308389859636 1.0 0.9573879296586668 19 Q9NVI1,Q9BXW9,P41208,P54277,P54727,P13010 6 +R2tp complex 0.4153756211634107 0.2770018938399932 0.7817786519533201 1.0 0.9573879296586668 4 Q9H6T3,Q9Y230,Q9NWS0 3 +Leading edge membrane 0.2202047755250624 0.2658098231403076 0.7903856775264917 1.0 0.9643351133227284 43 P15531,Q13325,Q96AC1,P15311,Q9UNF0,Q9Y2J2,O75122,P23396,Q16512 9 +Cluster of actin based cell projections 0.2239982771676912 0.2626077904774746 0.7928528948316562 1.0 0.9646054041993096 34 Q14728,P08238,O00299,P47755,P40855,Q9UEY8,P43034,P15311,P12814,O14745,Q9Y5X3,Q9Y6M7,Q6IBS0,P60660,Q13045,Q9UHB6 16 +Pcg protein complex 0.3550719092596531 0.2512352534418461 0.8016322301170702 1.0 0.9655648385985864 6 Q14157 1 +Preribosome small subunit precursor 0.2845004394960363 0.2498374926584366 0.8027130240019362 1.0 0.9655648385985864 12 P56182,Q96GA3,P05386,Q8IY81,Q2NL82,Q86U38,Q9BVI4,Q9ULX3,Q13895,O75691,P78316 11 +Filamentous actin 0.2899824253075609 0.2467584407666143 0.8050951754730882 1.0 0.9663277636646485 11 Q9Y2A7,Q9NR12,Q69YQ0,Q96HC4,Q5M775,Q9UM54,Q14195,Q8NDI1,Q9Y5K6,O00151 10 +Neuromuscular junction 0.2568420590035232 0.2368988678212699 0.8127352483393175 1.0 0.9703501315924568 18 Q12955,P07196,P46109,Q00535 4 +Cell projection membrane 0.2055420628098892 0.2218313165352194 0.8244451996863742 1.0 0.9768650200285648 68 Q14728,Q16658,Q13325,P26038,O15144,Q15691,O60610,P15311,Q16512,Q12792,Q96AC1,Q9UNF0,Q9Y2J2,P23396,Q15019,O95721,P15531,P06744,P08238,P31751,P40855,P23528,Q9Y217,P62330,P09497,O75122,Q9UHB6,Q9H4M9 28 +Site of dna damage 0.2118612111943382 0.2177922007238489 0.8275910216297868 1.0 0.9768650200285648 44 Q93034,Q9H4L7,P35244,Q9Y3Z3,Q14241,O95251,P83916,Q9UNS1,O60921 9 +Inclusion body 0.2264283783358059 0.216234271726734 0.8288051404368075 1.0 0.9768650200285648 29 P13807,P07197,P08238,P62195,P62333,P13639,P27695,O95817,Q9UL15,P35573,P42858 11 +Ribonuclease p complex 0.3698830409356717 0.214617671879279 0.8300654148088025 1.0 0.9768650200285648 5 Q99575,P78346,Q99714,Q7L0Y3 4 +9plus2 motile cilium 0.2433022990374452 0.209659159515722 0.8339337030116716 1.0 0.9774714647691476 22 P41208,P21266 2 +Histone methyltransferase complex 0.2452010746883176 0.2095292896267253 0.8340350729795574 1.0 0.9774714647691476 21 Q9UBL3 1 +Nuclear pore 0.2088949131792524 0.2079170029704692 0.8352937728288705 1.0 0.9774714647691476 48 P41208,Q9NZZ3,Q9H6Z4,Q9C0E2,Q9HD42 5 +Rna polymerase ii transcription regulator complex 0.2102965255060465 0.1898685636057192 0.8494121269443873 1.0 0.9855358652367572 37 P18074,O60244,Q96T76,Q8N3C0,Q15648,O00716,P42224,Q9ULK4,Q9H1I8,P29083,P23193,P13984,O75448 13 +Nls dependent protein nuclear import complex 0.3316142219649727 0.1867643164310328 0.851845425943565 1.0 0.9867330586172598 6 P52294,O60684 2 +Brisc complex 0.4668310096335908 0.1791141617801705 0.8578480623348133 1.0 0.9870014755071372 3 Q15018 1 +Glycogen granule 0.4620105201636282 0.1705651583327231 0.8645656960187604 1.0 0.9870014755071372 3 P49327,P62140 2 +Rna cap binding complex 0.3208540508920606 0.1606688700154696 0.872354208975082 1.0 0.9870014755071372 6 P06730,Q7L576,O43148,Q09161,Q06787 5 +Myosin filament 0.4511981297486678 0.1524731990497646 0.8788137273282681 1.0 0.9870014755071372 3 Q7Z406,P35579 2 +Neuronal ribonucleoprotein granule 0.4557405784399804 0.1476278721487894 0.882636457318247 1.0 0.9870014755071372 2 Q06787 1 +Polar microtubule 0.4450613676212565 0.142870389985076 0.8863925440035687 1.0 0.9870014755071372 3 P23258,Q96CW5 2 +M band 0.4444769140853233 0.1419808825492887 0.8870951062123467 1.0 0.9870014755071372 3 P06733,P04075 2 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.3532910697547357 0.1377411403397951 0.8904450039842355 1.0 0.9870014755071372 4 Q9P287 1 +Camp dependent protein kinase complex 0.3516515638702121 0.1348899137439551 0.8926989143310131 1.0 0.9870014755071372 4 P13861,P17612,P10644 3 +Ciliary base 0.2876026683438508 0.1263573698661493 0.8994490455323079 1.0 0.9870014755071372 7 A0AVF1 1 +Ubiquitin ligase complex 0.1898676585563562 0.1165587965992809 0.90720969063825 1.0 0.9870014755071372 67 Q93034,O95155,Q6NTF9,Q15370,Q96K76,Q9HC52,Q16763,Q9NXV2,O75448,Q9HB71,P68036,Q9NZJ0,P46934,Q9NT62,Q96GG9,Q9NXF7,Q9Y4B6,Q86VP6,Q13309,Q9UBU6 20 +Ribonucleoprotein granule 0.1955701384932064 0.108349766215531 0.9137182472105718 1.0 0.9870014755071372 118 Q96C86,P51114,Q5T6F2,P62701,Q93062,P67809,P19474,Q96F86,Q6PKG0,Q14258,Q5TAX3,Q14011,P60900,Q9UN86,P07437,P17980,P30740,O95793,P25789,P06730,A5YKK6,P25787,O75116,Q14157,Q04637,Q92879,P46940,Q9Y5A9,Q9HCE1,Q9NUL3,Q9HAU5,Q7Z739,P62753,P05388,Q13283,Q15365,Q9NPI6 37 +Golgi cis cisterna 0.4268185801928175 0.1079538753243932 0.9140322804626356 1.0 0.9870014755071372 2 Q15334 1 +Endoplasmic reticulum exit site 0.2149623262266226 0.1061944216564736 0.9154280967943104 1.0 0.9870014755071372 21 Q15436,Q15437,O95486,Q9NR31 4 +Somatodendritic compartment 0.1902204158862935 0.1059568127888737 0.9156166176300272 1.0 0.9870014755071372 154 Q96A49,P30153,P42345,P51114,P25685,Q12955,P07900,Q14203,Q16512,Q9H814,Q6SZW1,Q9HD26,Q02952,P27695,Q9Y296,Q9Y4F1,Q9UQB8,P17612,P78559,O95793,Q13740,P42858,P08238,O43815,P49841,P40818,Q9UKA9,Q9UBB6,Q02790,P46934,P98179,Q00535,Q13614,P46821,P52294,P12277,Q9NUL3,P62753,P43034,Q13283,Q9P265,O14965,Q7Z460,P04350 44 +Exon exon junction complex 0.3166666666666646 0.1058801496915056 0.9156774437771495 1.0 0.9870014755071372 5 Q9BZI7,Q9Y5S9,Q92900,Q9HAU5 4 +Ubiquitin conjugating enzyme complex 0.4161309175920437 0.103980316236248 0.917184969253074 1.0 0.9870014755071372 3 Q5VTR2,O75150 2 +Clathrin vesicle coat 0.2302959273366407 0.0963731681428678 0.9232242016325938 1.0 0.989427052376992 12 Q00610,Q14677,Q96CW1,P53680,P63010,P09497,P09496,O94973,O43747,O95782,Q9NVZ3 11 +Endoplasmic reticulum golgi intermediate compartment 0.1866994153155378 0.0884505237938533 0.9295186064355274 1.0 0.989427052376992 49 P09429,P24390,P53990,O15260,P80303 5 +Presynaptic endocytic zone 0.3953828170660386 0.082290506254799 0.9344157037274268 1.0 0.9909871363343224 3 P09497,Q13492 2 +Cell substrate junction 0.2079561694094115 0.070334095801829 0.9439277451680614 1.0 0.9921656322614352 195 Q15691,P05386,P62701,Q15942,P04083,Q8WX93,Q13642,P84098,O15145,P08670,P18206,P04792,P23528,Q01518,Q99439,P29966,Q9UHD1,Q92542,P05387,P32969,Q14247,Q13283,Q7Z460,Q9UGI8,P62917,P36507,P15311,P15880,O00560,P62280,P46777,Q12792,P61247,P61513,P61978,P42356,P50570,P50395,Q16527,P07737,Q13740,P62899,P39019,Q8N8S7,P62081,Q15555,P62277,P05388,O75122,P46783,Q16512,Q9UNN8,P62841,Q02952,Q96AC1,P23396,O60504,P62241,P62906,P67936,P39023,P63104,P22392,Q9UJW0,P27348,P62330,P11233,P08708,O15144,P26038,P61981,P46781,P62269,Q15417,P31946,Q02750,Q9UNF0,P35241,P62258,Q13045,P46940,P35613,Q9UHB6,Q9UL25 84 +Transport vesicle 0.1946755012868648 0.067588412141098 0.946113280076943 1.0 0.9933091861596676 98 Q7Z6M1,O15260,O00461,P24390,Q9Y678,Q9Y296,O95486,O95487,Q9Y6Y8,Q15019,Q92572,Q15437,P61923,Q9UHD1,P20645,Q13614,Q9NR31,P0DP25,Q15436,Q92905 20 +Mitotic spindle 0.1840238680528517 0.0581497248616885 0.9536293666592316 1.0 0.9966680825126564 73 Q15691,Q5SW79,Q9HC35,Q9H6D7,Q9P287,Q9BPX3,Q9Y266,Q14674,Q9P258,Q14203,O14965,O75122,Q15051,P23396,Q7Z460,Q96CS2 16 +Microvillus membrane 0.2844352427889637 0.0533252783227277 0.957472739662391 1.0 0.9966680825126564 4 P15311,P26038 2 +Pml body 0.1752356267543074 0.0508501203282658 0.9594449522604184 1.0 0.9966680825126564 31 Q13535,Q13137 2 +Perinuclear region of cytoplasm 0.213673222376196 0.0481198258521458 0.961620745762001 1.0 0.9966680825126564 213 Q96A49,Q9UN37,Q99497,P26038,O00299,Q9H2J4,P51114,P30044,P36507,Q6NTF9,P42224,P15311,Q9UPY3,Q14677,P55145,P55327,P31946,Q01105,Q9UNN8,P39687,Q9UI30,Q96HP0,P27695,Q15004,Q15056,P31689,O60271,Q9UHD8,Q9P289,Q9H4L5,Q9H223,P17612,P19525,Q13137,P42858,O75821,O75935,P08238,P16989,Q15437,Q13177,Q7L5N1,Q27J81,Q02790,P46934,Q8NCE2,P20645,O95831,Q9Y5X3,Q99598,Q13614,O60763,Q9Y217,P46821,P30041,O95999,Q9H267,Q9UNS2,Q9UII4,P62753,P43034,P25205,Q15436,Q6IBS0,O14965,Q92905,O75190,P07900,Q9UNN5 69 +Mhc class i protein complex 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 0.9966680825126564 2 P04439 1 +Mhc protein complex 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 0.9966680825126564 2 P04439 1 +Ccr4 not core complex 0.323495032144946 0.0399788041329846 0.9681100246324714 1.0 0.9977517402375028 3 Q9UIV1,A5YKK6 2 +Escrt i complex 0.2413793103448329 0.0282180465246002 0.977488243909852 1.0 1.0 3 Q9H9H4,Q99816 2 +Actin based cell projection 0.1685089471072609 0.0264983684544233 0.978859834928188 1.0 1.0 47 Q16658,P26038,Q9Y6M7,P51114,P43034,P15311,O15357,P35241,P62330,Q9Y4F1,Q9H4L5,Q9UQB8,Q6IBS0,Q8N8S7,Q12792,Q14204,Q00535 17 +Chromosome centromeric region 0.1870046147955681 0.0252183017533101 0.979880838910112 1.0 1.0 98 P30153,P33981,O95251,Q9UEE9,Q14203,P48729,Q92674,Q9NZZ3,Q9HBM1,P83916,Q9Y6G9,Q15019,O43670,Q9BPX3,O43237,Q9HD42,Q9UJW0,Q96DY7,P42695,P43034,Q6P1K2,O75122,Q7Z460 23 +Lamellipodium 0.1709775555248518 0.0182838274821326 0.985412429110958 1.0 1.0 66 Q9P2B4,P22392,Q96AC1,Q13596,Q9UQB8,Q16512 6 +Brush border 0.1531755794314002 0.0104877554818808 0.9916321352249255 1.0 1.0 30 Q14728,P08238,O00299,P47755,P40855,Q9UEY8,P15311,P12814,O14745,Q9Y5X3,Q9UHB6,P60660,Q13045 13 +Adherens junction 0.1606118190646387 0.0026968365284475 0.9978482383792104 1.0 1.0 49 P04083 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3589975b96b51d16c715fe5379283046d0ff4044 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of the cytoplasmic side of the plasma membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG3", "ATG5", "ATG7", "ATG9A", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPI", "CENPV", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COASY", "COG3", "COG4", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM210B", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK3", "HOXD11", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITM2C", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K4", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METTL1", "METTL13", "METTL14", "METTL3", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGA", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NFKBIE", "NFRKB", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PAOX", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBRM1", "PBXIP1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLK2", "TLN1", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC28", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UIMC1", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP30", "USP32", "USP33", "USP36", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", 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"ANP32A", "ANXA1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3S1", "APEX1", "APRT", "ARCN1", "ARF6", "ARL3", "ARPC2", "ARPC3", "ASCC2", "ASCC3", "ASH2L", "ATG3", "ATG7", "ATP11C", "ATR", "ATXN2L", "AURKA", "BAG3", "BAG5", "BAIAP2", "BCAS3", "BCCIP", "BCL10", "BICD2", "BRAP", "BSG", "BTF3", "BYSL", "C1orf35", "CACYBP", "CALCOCO2", "CALM3", "CALU", "CAMK1", "CAND1", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBX1", "CBX8", "CCDC124", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CD2AP", "CDC37", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CELF1", "CENPI", "CEP170", "CETN2", "CFDP1", "CFL1", "CHD3", "CHMP1A", "CHMP5", "CHORDC1", "CHUK", "CIRBP", "CKB", "CLASP1", "CLASP2", "CLIC1", "CLINT1", "CLTA", "CLTB", "CLTC", "CNN2", "CNN3", "CNOT1", "CNOT7", "COG4", "COG5", "COG7", "COPA", "COPB2", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS7A", "COPZ1", "COTL1", "CPPED1", "CRKL", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CTBP1", "CTTN", "CTTNBP2NL", "CUL4B", "CUL5", "CYFIP1", "DARS", "DCAF1", "DCAF16", "DCP1A", "DCPS", "DCTN1", "DCTN3", "DCTN4", "DCUN1D1", "DDX1", "DDX6", "DENND4C", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIP2B", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB6", "DNAJC13", "DNAJC8", "DNAJC9", "DNM2", "DOCK6", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DTL", "DTX3L", "DUSP3", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "E2F3", "EDC3", "EEA1", "EEF1E1", "EEF2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3J", "EIF3K", "EIF3L", "EIF4A1", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4H", "EIF5A", "ELL", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP6", "EML4", "ENAH", "ENO1", "EPB41L3", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERCC2", "ESPL1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EYA3", "EZR", "FAF1", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FARP1", "FASN", "FERMT2", "FHL1", "FKBP15", "FKBP1A", "FKBP4", "FLII", "FMR1", "FSCN1", "FTSJ3", "FXR1", "G3BP1", "G3BP2", "GCN1", "GDI2", "GEMIN4", "GEMIN5", "GGA1", "GIGYF2", "GINS2", "GINS4", "GLRX3", "GNS", "GOLIM4", "GOPC", "GPHN", "GPI", "GSK3B", "GSTM2", "GSTM3", "GTF2E1", "GTF2F1", "GTF2F2", "GUSB", "GYG1", "GYS1", "HAUS1", "HAUS4", "HAUS5", "HERC5", "HGS", "HLA-A", "HMCES", "HMGB1", "HNRNPK", "HOOK3", "HPS6", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSPB1", "HTT", "HUS1", "HUWE1", "IARS", "ICE2", "IDH1", "IDH2", "IFIT5", "IGHMBP2", "INA", "INF2", "INPPL1", "IQCB1", "IQGAP1", "IST1", "ISY1", "ITCH", "KARS", "KAT7", "KCTD5", "KDELR1", "KIF13B", "KIF1A", "KIF3A", "KLC1", "KPNA1", "KPNA6", "LARP1", "LARP4", "LARP4B", "LARS", "LGALS3", "LIMA1", "LLGL1", "LRWD1", "LTA4H", "LTV1", "M6PR", "MAGED2", "MANF", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP7D3", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MAT2B", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MED1", "MED14", "MED23", "MED24", "METTL1", "MFSD10", "MIF", "MMS19", "MOV10", "MRPS5", "MSN", "MTBP", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPN", "MYH14", "MYH9", "MYL6", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCKAP1", "NCKIPSD", "NCSTN", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NME1", "NME2", "NOB1", "NOC4L", "NOP14", "NOP9", "NR3C1", "NRBP1", "NRP1", "NSUN2", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUSAP1", "OCRL", "OLA1", "ORC3", "OSBPL3", "OSGEP", "PA2G4", "PABPC1", "PABPC4", "PACSIN2", "PAFAH1B1", "PAK2", "PALLD", "PARK7", "PBXIP1", "PCBP1", "PCLAF", "PCNA", "PCYOX1L", "PDAP1", "PDCL3", "PDE6D", "PDLIM1", "PDLIM5", "PDLIM7", "PEX19", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKM", "PFN1", "PFN2", "PGAM1", "PGM1", "PGM2", "PHAX", "PI4KA", "PICALM", "PIGU", "PIH1D1", "PIK3C3", "PIK3R4", "PIN1", "PKM", "PKN1", "PLD3", "PMF1", "PMS1", "PNP", "POLD1", "POLE", "POLE2", "POLR3E", "POP1", "PPP1CB", "PPP2R1A", "PPP2R1B", 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sha256:b9c6658907bfbf866edb2d28df04f5110f964c37fa3c76d3d956635e8305f64d +size 145637 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..ccd968f5e2ab65aae5da9dcd10737efc3be22883 --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:07f4ba54f91111b1979e8442845f1547e51c2081bf4885f061b0418860142547 +size 147545 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..74cc2efd2e958b5e53877d2b98c16c9342c5ecf3 --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:403304f6e5a8f916746f2e5bf468ca35381f28324289cdfa5cff0b7a840aa539 +size 147945 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..90993b0b582841ea7bca93003655eb9b3a62bad3 --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:30f7d3749976026eb222b4d56a7b3c191981d5159e437819a6a0aa6774aab88e +size 153573 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..87f824f6b4efbbde0b061ec183e23690e6eca407 --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ef494018b2bb71ff947836f5f4e4894dad001e11066146fd70dfd89e07b92d4 +size 147472 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..6f458c50f4cb3c59b1f111ac4310c3a7dc031b4c --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0edd1b55a1cc42c240846d25923de68d90dbe3dd15c8695cf2fc2ff6235c3ea7 +size 145073 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..918ea81ff678603179d6c88129f2705e1433f641 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cba88c461fbe05c4ab903a5edf1ab1e7ce2a814db4fb7cf8b9f3f3e9d476bafe +size 146164 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7d98fe116a32f99503ac2df2cadb3ff6c86d1fe0 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd2631bf5d186ad71422c891f8e2a4e5a56516dab9015e4d3bb4f637f6014d7d +size 185409 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8170c2b4b0e9291d5088ba347d34e22e00e90b50 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,44 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Magnesium ion binding 33 75 3.5205290958192506 0.0004306867384091 21.71359223300971 72.79368932038835 -0.6147406093040623 0.4604947617504717 10.953144235755325 6.885940296543083 1.1504366681720746 0.3542485598642225 0.0176539819531368 0.0001846725890871 0.007676739672567 0.0726335319959773 0.0998823252317074 +Peptidase activity 29 123 3.263090101470058 0.0011020447659135 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 1.0 0.0023383040522242 0.0019373937268069 8.60722361682405e-06 3.4351155162785666e-05 +Threonine type peptidase activity 7 9 3.190857667153856 0.0014185114307583 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 1.0 3.4371927832486704e-05 0.0002902447274798 1.3739294521393221e-08 6.875137584646856e-08 +Threonine type endopeptidase activity 7 8 3.102730848402799 0.0019174393840755 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.148254609278584e-05 9.839858993160587e-05 5.22260781759681e-10 1.22573214543153e-09 +Phosphoric ester hydrolase activity 24 68 3.0154146816343066 0.0025662812715847 13.983009708737864 63.310679611650485 0.0419549724534753 0.6140737111070494 7.163296596269021 9.21904858538458 0.8993707212934827 0.3266109107762958 1.0 0.0295630651540025 0.0331776056462107 0.0419027565404997 0.4431164022439814 +Translation regulator activity 50 82 2.9509223445191424 0.0031682656171221 25.199029126213592 78.43203883495146 -0.1449572932869035 0.5916688790638589 11.530424045500434 2.964636672584618 1.1118561159381193 0.3577333285619786 1.0 0.4315404604316775 0.68527292971009 0.0700698804459473 0.0128915807124532 +Translation regulator activity nucleic acid binding 43 66 2.9085307009608456 0.0036313151964164 20.885922330097088 62.970873786407765 -0.2153316283409681 0.5810585562874645 10.014266322329854 2.613283136412972 1.123797243693277 0.357239690044585 1.0 0.356510309215238 0.5943645192903619 0.190428756515485 0.0366398150951155 +Phosphatase activity 22 56 2.9047512744918427 0.0036754504875138 13.145631067961164 51.94174757281554 -0.2136566108287436 0.5782522454352085 6.712772591402836 8.480503331277838 1.0011340610450716 0.3419346460390784 1.0 0.0668087997235459 0.0426118271714143 0.0235527071590617 0.3755778881442584 +Translation initiation factor activity 32 38 2.756028938787694 0.0058507820279056 12.41504854368932 36.407766990291265 -0.0620726684038362 0.6020098880208691 6.262080887091644 1.941808251479095 1.008453552811725 0.334422762452143 1.0 1.0 1.0 0.1057864538742936 0.0071658996193174 +Endopeptidase activity 22 71 2.7275936391801707 0.0063798147198552 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 1.0 0.0075552513162859 0.0217463504945621 0.0002020221247156 0.0011723818152273 +Nadp binding 3 19 2.706923978895185 0.006790980617668 3.966019417475728 17.985436893203882 0.66085030998649 0.497161667914878 2.1141710210905544 1.9470619024167608 0.8006079385844883 0.3067322240884021 1.0 0.0005765764868268 0.0045096021611559 0.0098961463934591 0.0062617463102783 +Kinase activity 64 154 2.629172949129892 0.0085592818168036 35.16019417475728 132.373786407767 -0.2468132143986984 0.650700950478703 14.107719017779814 21.937269175241475 0.8173764292711447 0.324368436915093 1.0 0.4685304233770016 0.4149063133870655 0.5509666777509539 0.3083234746658899 +Translation factor activity rna binding 36 56 2.571058815751688 0.0101388106337303 20.436893203883496 53.987864077669904 -0.3875060502954274 0.548917367166947 8.785104232007459 2.1344034206559086 1.1881193244272017 0.366265044062608 1.0 1.0 1.0 0.2950347285537182 0.0352514528543702 +Hydrolase activity acting on ether bonds 1 7 2.5625488222403554 0.0103906977528005 1.733009708737864 6.473300970873787 0.442831885081079 0.3761322348666416 1.4402594392445152 0.6511869496520301 1.1243392396889562 0.2763300958015678 1.0 0.0370595951599339 0.002465796513642 0.014977467250991 0.0544194668097373 +Phosphatase regulator activity 16 31 2.5447992181173715 0.0109340588558211 5.890776699029126 21.42718446601942 0.2207502835350587 0.5696921397829399 3.3115291951500065 3.3518635354302604 0.8778999195679603 0.2968997706719961 1.0 1.0 0.175896893635733 0.003025768786718 0.0376283333624949 +Channel inhibitor activity 5 7 2.50605638317177 0.0122086149803721 1.7087378640776698 5.25 0.2401531921347128 0.4896377856970755 1.2647657441579596 1.4032296312643389 1.0246578428578517 0.3110954032816434 1.0 1.0 0.0155240337321844 0.0119341177484456 0.01439805670462 +Protein phosphatase regulator activity 15 26 2.488515186808027 0.0128277758373358 5.211165048543689 18.79368932038835 0.2673383696568306 0.5750752516699464 3.016390758136069 2.679236773763369 0.8397594774518536 0.2970107094313646 1.0 1.0 0.1226746045160812 0.0008019259714474 0.0109011131386191 +Dynactin binding 6 7 2.4769675603039167 0.0132503944605322 2.150485436893204 5.584951456310679 0.2775355704886244 0.5227141328346228 1.318897287741983 1.161713977954793 0.9194793023459098 0.3062784805257165 1.0 1.0 1.0 0.0233125205204954 2.285385949037992e-06 +Dynein intermediate chain binding 5 9 2.438250912850222 0.014758525967224 4.024271844660194 8.356796116504855 -0.3936325078469428 0.4786176428399276 2.2108279879085795 1.390458968433639 0.9585299422118524 0.3097940715454363 1.0 1.0 1.0 0.0840389641709933 0.01439805670462 +Glutathione transferase activity 2 7 2.403036680573687 0.0162595564079981 2.388349514563106 7.058252427184466 -0.0343576890242698 0.5012486650417416 1.627929829054375 0.961140531216188 0.972915170615138 0.2930270921886944 1.0 0.0550816697898294 0.1094892401774078 0.0026581093268102 0.0181181417645757 +Nad binding 2 32 2.376065138600878 0.0174983734617197 8.563106796116505 29.28640776699029 -0.1611005483208177 0.4805202036040635 4.8695006879309135 2.252401029309141 1.131878946797942 0.3253122423834694 1.0 0.0173338143393145 0.0640285846884502 0.0862589503665335 0.3487517012854798 +Isocitrate dehydrogenase activity 1 5 2.343781263498936 0.0190893630126129 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002150789234385 0.0008973897437505 0.0056136137273067 0.0214122317398669 +Signaling receptor regulator activity 9 16 2.339474283346745 0.0193109009998369 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 1.0 0.2922756805728106 0.1554832015057707 0.5335587935482642 0.2817090990841858 +Endoribonuclease activity producing 5 phosphomonoesters 2 14 2.320474080914644 0.0203152454612751 4.014563106796117 13.847087378640778 0.0590502559174568 0.5141921644734302 2.967425341712726 1.9404774365308557 0.986622122238027 0.2967225187013733 1.0 0.0003283386212269 0.0026246094830452 0.0326106125072858 0.0501437556032915 +Pyrimidine nucleotide binding 0 5 2.3176227243710983 0.0204698340812166 1.172330097087379 5.012135922330097 0.2915756451416036 0.3812019786090051 1.420006634664861 0.3375357600197503 1.227384965028187 0.3091745000997537 0.0005884660651103 0.0279227766388577 0.0563150378970086 0.1373795195898598 0.2586577321272367 +Translation repressor activity 1 10 2.2680128428758235 0.0233284239161093 2.621359223300971 8.691747572815533 0.8178109552751379 0.3869214297451314 1.7535899646617803 1.1146116282865457 0.9030508481280868 0.2968248594231644 1.0 0.0944323477659319 0.1837383274168749 0.0914454637274335 0.2722934148112151 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 2 16 2.2676066689364216 0.0233531908541784 4.584951456310679 15.434466019417476 -0.0004665177245218 0.5167656770846271 3.3144383682115186 2.0745982079847356 0.9993199709785272 0.3071343698196139 1.0 0.0006269196579584 0.004885623522166 0.0563589352178582 0.0957448321565225 +Protein tyrosine serine threonine phosphatase activity 3 6 2.264382811875513 0.0235505801940436 1.8810679611650485 4.468446601941747 -0.3523034759706301 0.5163059400013565 1.2079553555543134 1.4931801322488931 0.9919404315866904 0.3223205189153811 1.0 1.0 0.0274603336438859 0.0038594647505617 0.0399552443236748 +Protein serine kinase activity 41 73 2.2050771340191964 0.0274486823334443 18.606796116504853 58.79368932038835 -0.2547746046050501 0.5863977102077378 8.497901078786414 12.25769657088421 0.9472615480729644 0.3269248883217332 1.0 0.7290395724580129 0.7428710491917419 0.6569751676940332 0.4588669782443905 +Epoxide hydrolase activity 0 5 2.1910173066928365 0.0284505400752275 1.1019417475728157 4.521844660194175 0.5286018285197666 0.3719344719688537 1.0354381449156973 0.6208422834489354 1.1335270265758153 0.2772966130846634 1.0 0.0233225886554715 0.0471521402185075 0.1158638926054548 0.2207303711304172 +Ether hydrolase activity 0 5 2.1910173066928365 0.0284505400752275 1.1019417475728157 4.521844660194175 0.5286018285197666 0.3719344719688537 1.0354381449156973 0.6208422834489354 1.1335270265758153 0.2772966130846634 1.0 0.0233225886554715 0.0471521402185075 0.1158638926054548 0.2207303711304172 +Translation repressor activity mrna regulatory element binding 0 7 2.169772215013298 0.0300241062279964 1.5995145631067962 6.174757281553398 0.6534600204791633 0.3949783065671634 1.3392142882982137 0.7026604707853292 0.9849198932748844 0.2965869521608698 1.0 0.0550816697898294 0.1094892401774078 0.2559514735144251 0.4505109675601652 +Ubiquitin binding 12 33 2.1528115737953946 0.0313334901785427 8.74757281553398 29.194174757281555 -0.2394500404433165 0.5969657249917615 4.006592738339085 4.26331894146384 0.8579159018639084 0.311349671576461 1.0 0.356510309215238 0.0601458293215769 0.0074315744767491 0.0146697722759854 +Phosphoprotein phosphatase activity 17 37 2.144335442859117 0.0320060188736142 10.91747572815534 31.54854368932039 -0.7567339126100434 0.4537279867564764 4.673617903472994 5.5332246971419945 1.126677076303839 0.3483654379821215 1.0 1.0 0.3491903780040699 0.0919536121874529 0.5959270700670929 +Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor 0 8 2.1029696859653426 0.0354684194567593 3.3155339805825244 9.1747572815534 -0.0822659283487201 0.520789618970474 2.835703617469018 1.0397645781526508 0.9371302185048814 0.2942319480110578 1.0 0.0727733471903131 0.1432798584585485 0.3258327648280404 0.5500037614421638 +Organic cation transmembrane transporter activity 0 6 2.091472770253281 0.0364857048740359 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 1.0 0.0639684350193291 0.1265462710440741 0.2917500038862815 0.5027345059494577 +Cytokine receptor binding 12 23 2.09102206588676 0.0365260859965828 5.922330097087379 21.781553398058257 0.3813901154695622 0.6128380053861922 3.0930216488350233 2.799245653337908 0.7910605683641851 0.3254820565664404 1.0 0.058039929090825 0.1897338295109766 0.3284623958158804 0.108533579096118 +Nadph binding 0 6 2.083835390682648 0.037175142937261 1.3786407766990292 5.429611650485437 0.8367704566864596 0.3914568233833007 1.0938176207501296 1.2950229014206938 0.8806674554162238 0.2962147259816868 1.0 0.0639684350193291 0.1265462710440741 0.2917500038862815 0.1462762019757018 +Oligopeptide binding 2 5 2.0801188662750865 0.0375146315469727 1.7160194174757282 5.063106796116505 0.0293647829039082 0.5634093508387062 1.1842148189779755 0.7979938792453463 0.8584653877950488 0.2945637220042438 1.0 0.0370595951599339 0.0743799864466655 0.0007272762906085 0.0053334351931861 +Protein serine threonine tyrosine kinase activity 42 78 2.0622122640062157 0.0391875316105354 19.475728155339805 63.939320388349515 -0.3064367199223224 0.6001763214586637 8.904122161116224 13.055843743274796 0.8725878237254184 0.322654526690802 1.0 0.7854233053739825 0.8193176338545933 0.7982908714219653 0.7024393021907948 +Sequence specific mrna binding 1 7 2.052655740539788 0.0401059774152861 1.9781553398058251 7.055825242718447 0.3565707953589194 0.5160285018516239 1.90604773194484 0.8472056000069838 0.905099421878169 0.3060605024329414 1.0 0.0506073598520519 0.1008375048293403 0.0280420066437826 0.0971506673250001 +Map kinase kinase activity 3 6 2.045935711184389 0.040762696256563 2.7985436893203883 5.410194174757281 -0.1467331462793099 0.5414907676553348 1.7778840416537216 1.4087772571824178 0.9108945712596545 0.3122036123079633 1.0 0.0683810764565047 0.1349531130589082 0.050241067872642 0.0336357980244025 +Dipeptidase activity 2 5 1.97855648334778 0.0478659632501239 2.0485436893203883 4.050970873786408 -0.5893623598810716 0.427687858734097 1.1438195320406324 0.7631208464824752 1.0101774335827358 0.3085940867530516 1.0 1.0 0.0832836732680532 0.1988473022417859 0.00771353919978 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ac9934304ef98fb4969e4f7c0d3af9c1d73b8d4d --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 1414, + "title": "Average number of proteins per term", + "value": 17.53041018387553 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..859073a0f5d9c19bee1c0b2481ace6bd795e1443 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b8d019a0a82544715dc88be8c5c1e14997da9e1d --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,449 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Magnesium ion binding 0.5010658982557838 3.5205290958192506 0.0004306867384091 0.4561719833424921 0.0917070747987643 75 Q9H773,P48735,Q14558,P34913,O75874,A6NDG6,Q969T7,Q13043,P24941,P62826,P60891,P51003,Q96G03,Q13572,Q9BQG2,O60256,P14618,P17612,P39748,P15531,P52701,P49642,Q9H2U2,P36871,Q8NB49,Q9NRN7,P33316,Q96SB4,Q9UKK9,P11908,O95747,Q7Z460,Q9UBT2 33 +Peptidase activity 0.4087530430740453 3.263090101470058 0.0011020447659135 0.7896853599784867 0.0917070747987643 123 P51665,O43847,Q92995,P49721,P28070,P28074,Q96E52,P81605,P20618,Q9H3G5,P60900,Q14674,Q0VDG4,Q12765,P25789,Q99436,Q96FW1,Q86TI2,P42785,Q7L5N1,Q96KP4,Q4J6C6,Q9HD42,Q01804,Q6P179,P28072,O94966,P49720,Q92905 29 +Threonine type peptidase activity 0.8985562412179744 3.190857667153856 0.0014185114307583 0.8656355127187477 0.0917070747987643 9 P20618,Q99436,P49721,P28072,P28070,P28074,P49720 7 +Threonine type endopeptidase activity 0.9075212174422068 3.102730848402799 0.0019174393840755 0.9337196598389184 0.0917070747987643 8 P20618,Q99436,P49721,P28072,P28070,P28074,P49720 7 +Phosphoric ester hydrolase activity 0.4550226267131928 3.0154146816343066 0.0025662812715847 0.9735734438510032 0.0917070747987643 68 P34913,P30153,Q99504,Q8N2A8,A6NDG6,O15355,Q9NPH0,Q969T7,Q06124,P53041,Q9H0R4,Q8TF05,Q9Y3Z3,Q14738,Q9BRF8,Q9UNI6,Q9H2U2,Q01968,Q8NCE2,O60942,Q13614,Q8IV08,P51452,Q9NQ88 24 +Translation regulator activity 0.4451070086910901 2.9509223445191424 0.0031682656171221 0.9887460872216632 0.0917070747987643 82 P24534,P00374,Q14232,P51114,P27635,P20042,P04818,P13639,P60228,Q8NE71,Q9UBQ5,O75822,P46781,O15372,P78344,P63241,P34896,P23588,Q6PKG0,Q9NR50,Q14240,Q9BPZ3,Q15056,Q14011,Q9ULC4,Q9Y450,P19525,Q05639,P46199,O75821,Q14152,P06730,P26641,O43432,P29692,P15170,Q04637,Q92616,Q9Y6M1,P60842,Q92879,P62495,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884,Q92905 50 +Translation regulator activity nucleic acid binding 0.4480632010164392 2.9085307009608456 0.0036313151964164 0.9941658409130012 0.0917070747987643 66 P24534,P00374,Q14232,P20042,P04818,P13639,P60228,Q9UBQ5,Q8NE71,O75822,O15372,P78344,P63241,P23588,Q6PKG0,Q9NR50,Q14240,Q9BPZ3,Q15056,Q9ULC4,Q9Y450,Q05639,P46199,O75821,Q14152,P06730,P26641,O43432,P29692,P15170,Q04637,Q92616,P60842,Q92879,P62495,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884,Q92905 43 +Phosphatase activity 0.4748654061335662 2.9047512744918427 0.0036754504875138 0.9945200608076604 0.0917070747987643 56 P34913,P30153,Q99504,A6NDG6,O15355,Q9NPH0,Q969T7,Q06124,P53041,Q9H0R4,Q8TF05,Q14738,Q9BRF8,Q5TFE4,Q9UNI6,Q9H2U2,Q01968,Q8NCE2,O60942,Q13614,P51452,Q9NQ88 22 +Translation initiation factor activity 0.5091731107648023 2.756028938787694 0.0058507820279056 0.9997508118638618 0.1134719883067467 38 Q9BY44,Q14232,P20042,P60228,Q9UBQ5,O75822,O15372,P78344,O00303,P05198,P23588,Q9NR50,Q14240,Q15056,Q9ULC4,P46199,Q7Z478,O75821,Q14152,P06730,O43432,Q9UI10,Q04637,P60842,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884,Q92905 32 +Endopeptidase activity 0.4285670556155108 2.7275936391801707 0.0063798147198552 0.9998826039543292 0.114190607770574 71 Q9BYT8,O43847,Q92995,P49721,P28070,P28074,Q96E52,Q13043,Q96K76,P20618,P60900,Q14674,P25789,Q99436,Q96RU2,P40818,Q4J6C6,Q6P179,P52888,P28072,P49720,Q92905 22 +Nadp binding 0.6508959440034167 2.7069239788951855 0.006790980617668 0.9999346138422444 0.1173818269306809 19 P00374,Q9UBM7,O75874 3 +Kinase activity 0.344314312624158 2.6291729491298916 0.0085592818168036 0.9999947375701984 0.1263451974532441 154 Q8IV63,Q99570,P42345,P55263,P36507,P04183,P49903,P33981,Q13043,P24941,P23919,Q9HA64,P51617,Q99640,P35790,Q16512,P60891,Q16539,P48729,Q00534,P42356,Q02750,Q13572,Q9H4A3,Q9BRR6,Q9HBU6,Q13535,Q9P289,Q14012,P14618,P17612,Q96KB5,P19525,P51570,P15531,P78356,P31751,P49841,Q8NEB9,O75116,Q13177,Q9Y3D8,Q9NVE7,Q13263,P78527,P22392,Q13546,Q99986,Q00535,O14874,Q96Q15,P12277,Q9UHY1,O95747,Q96SB4,Q9Y4B6,Q9UJ70,Q9Y223,P10398,P19784,P11908,O14965,Q7Z460,P06493 64 +Translation factor activity rna binding 0.4411932713464102 2.571058815751688 0.0101388106337303 0.9999994478519622 0.1419433488722248 56 P24534,Q14232,P20042,P60228,P13639,Q9UBQ5,Q8NE71,O75822,P78344,P63241,P23588,Q9NR50,Q14240,Q15056,Q9ULC4,Q9Y450,P46199,Q05639,O75821,Q14152,P06730,P26641,O43432,P29692,Q04637,Q92616,P60842,P62495,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884,Q92905 36 +Hydrolase activity acting on ether bonds 0.8382197129726663 2.5625488222403554 0.0103906977528005 0.9999996147263316 0.1440435943378429 7 P34913 1 +Phosphatase regulator activity 0.5122086435468277 2.5447992181173715 0.0109340588558211 0.9999998227854824 0.1501044584672917 31 Q96C90,Q15257,P17931,Q01105,P30154,P30153,Q9BTT0,P63151,O43768,Q8TF05,P0DP25,Q9NY27,Q5H9R7,Q14738,Q15435,P78318 16 +Channel inhibitor activity 0.825444710299418 2.50605638317177 0.0122086149803721 0.9999999713818798 0.1569361962022387 7 P62942,Q9H4A3,O43768,P46934,Q96PU5 5 +Protein phosphatase regulator activity 0.5571344680351976 2.488515186808027 0.0128277758373358 0.9999999882076848 0.1573320859192255 26 Q96C90,Q15257,P17931,Q01105,P30154,P30153,P63151,O43768,Q8TF05,P0DP25,Q9NY27,Q5H9R7,Q14738,Q15435,P78318 15 +Dynactin binding 0.8188999414862408 2.4769675603039167 0.0132503944605322 0.999999993563593 0.1573320859192255 7 P49841,Q86VS8,Q9UNH7,Q9Y5X3,Q8TD16,P42858 6 +Dynein intermediate chain binding 0.7373090421149681 2.438250912850222 0.014758525967224 0.9999999992597864 0.1656234580766254 9 Q86Y56,O95817,Q86VS8,P43034,P42858 5 +Glutathione transferase activity 0.8023662438632496 2.403036680573687 0.0162595564079981 0.9999999999142836 0.1741743390977982 7 P28161,O43813 2 +Nad binding 0.4801245816278867 2.376065138600878 0.0174983734617197 0.9999999999855704 0.1806036501815458 32 P48735,O75874 2 +Isocitrate dehydrogenase activity 0.8964725207226569 2.343781263498936 0.0190893630126129 0.9999999999985412 0.1886778928620558 5 P48735 1 +Signaling receptor regulator activity 0.6090071664806536 2.3394742833467452 0.0193109009998369 0.99999999999894 0.1886778928620558 16 P09429,P06744,P17931,P51858,P43490,Q9UMX5,P14174,P55145,Q00535 9 +Endoribonuclease activity producing 5 phosphomonoesters 0.6398842822357725 2.320474080914644 0.0203152454612751 0.9999999999997512 0.1940929532583992 14 Q9UQ84,Q8N2A8 2 +Translation repressor activity 0.6896972282689121 2.2680128428758235 0.0233284239161093 0.9999999999999968 0.2066179128496319 10 P00374 1 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.596964062075391 2.2676066689364216 0.0233531908541784 0.9999999999999968 0.2066179128496319 16 Q9UQ84,Q8N2A8 2 +Protein tyrosine serine threonine phosphatase activity 0.8192500431952414 2.264382811875513 0.0235505801940436 0.9999999999999976 0.2066179128496319 6 Q9UNI6,Q13614,O60942 3 +Protein serine kinase activity 0.382834621083889 2.2050771340191964 0.0274486823334443 1.0 0.2276099403665248 73 Q99570,P42345,P36507,P33981,Q13131,Q13043,P24941,P51617,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q9H2G2,Q14012,P17612,Q96KB5,P19525,P31751,P49841,O60566,O75116,Q13177,P78527,Q13546,Q99986,Q00535,Q96Q15,Q96SB4,Q9Y4B6,P10398,Q9NYV4,O14965,P19784,O95747,Q7Z460,P06493 41 +Ubiquitin binding 0.451189267299202 2.1528115737953946 0.0313334901785427 1.0 0.2346981607071489 33 Q9UJY5,Q9H4L7,O94888,Q96FW1,Q92995,P54727,P04792,Q92783,Q9H1I8,P54725,P46934,Q9UNN5 12 +Phosphoprotein phosphatase activity 0.440953945495651 2.144335442859117 0.0320060188736142 1.0 0.2369450821324109 37 Q9UNI6,O60942,Q15257,Q9Y217,Q13614,Q99504,P30153,Q9H2U2,Q8TF05,A6NDG6,O15355,Q8NCE2,Q14738,Q06124,P51452,Q9BRF8,P53041 17 +Lysophosphatidic acid phosphatase activity 0.9962021618463336 2.110820870100912 0.0347877115688124 1.0 0.2535557946304164 2 P34913 1 +Cytokine receptor binding 0.5259036426235647 2.09102206588676 0.0365260859965828 1.0 0.2547271361162596 23 P54577,P62942,Q13546,P48681,Q9H2J4,Q96AC1,Q96J02,Q9UNH7,P14174,P30046,Q8WUH2,O43776 12 +G protein coupled receptor activity 0.9891907683318732 2.0822478645716465 0.0373198353163508 1.0 0.2547271361162596 2 Q99720 1 +Oligopeptide binding 0.8324656233051468 2.0801188662750865 0.0375146315469727 1.0 0.2547271361162596 5 P28161,O43813 2 +Protein serine threonine tyrosine kinase activity 0.3707346485943442 2.0622122640062153 0.0391875316105354 1.0 0.2547271361162596 78 Q99570,P42345,P36507,P33981,Q13131,Q13043,P24941,P51617,Q99640,Q16512,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q9H2G2,Q14012,P17612,Q96KB5,P19525,P31751,O60566,P49841,O75116,Q13177,P78527,Q13546,Q99986,Q00535,P41240,Q96Q15,O95747,Q96SB4,Q9Y4B6,P10398,Q9NYV4,P19784,O14965,Q7Z460,P06493 42 +Dipeptidyl peptidase activity 0.8666865867821358 2.0613261536922245 0.0392719347053356 1.0 0.2547271361162596 4 Q86TI2 1 +Sequence specific mrna binding 0.7258608695079763 2.052655740539788 0.0401059774152861 1.0 0.2575786497500227 7 P00374 1 +Map kinase kinase activity 0.7692663864301753 2.045935711184389 0.040762696256563 1.0 0.25963266894946 6 Q16539,Q96KB5,Q02750 3 +Sodium channel inhibitor activity 0.973707274320772 2.018942933284458 0.0434931511822518 1.0 0.2695002581423725 2 Q96PU5 1 +Dipeptidase activity 0.8082630127087241 1.9785564833477796 0.0478659632501239 1.0 0.2855800507834398 5 Q0VDG4,Q12765 2 +Ubiquitin like protein binding 0.4174375872476478 1.9559302447039613 0.0504733719012922 1.0 0.2913034606874578 38 Q9UJY5,Q9H4L7,O94888,Q96FW1,Q92995,P54727,P04792,Q92783,Q9H1I8,P54725,P46934,Q9UBT2,Q96GG9,Q9UNN5 14 +Cytokine activity 0.8009204156444855 1.9475506710601764 0.051468751104581 1.0 0.2934548954107968 5 P09429,P06744,P43490 3 +Toxic substance binding 0.9544259421560072 1.9397321589980456 0.0524122491463421 1.0 0.295154866817683 2 P34913 1 +Oxidoreductase activity acting on the ch nh group of donors 0.624941386524657 1.9323902039035776 0.0533113622335141 1.0 0.295154866817683 10 P00374 1 +Endoribonuclease activity 0.5088848636465877 1.9303081372636504 0.0535686694040888 1.0 0.295154866817683 22 Q9UQ84,Q8N2A8 2 +Protein serine threonine phosphatase activity 0.5237849913791476 1.913704528491979 0.0556579201120761 1.0 0.3003828207575408 19 Q9UNI6,Q9Y217,P30153,Q9H2U2,O15355,Q8NCE2,Q9H0C8,P51452,Q9BRF8,P53041 10 +Heat shock protein binding 0.3693710343603713 1.8586160567924557 0.0630815794988268 1.0 0.3208537892494287 58 O95433,Q99543,O75937,P25685,P51617,P53041,Q16543,P31689,Q9Y4R8,P23396,P42858,P08238,P31948,Q15785,Q99615,P04150,Q02790,Q9UHD1,Q00059,Q8WXX5,Q00535,Q9UER7,O60884,Q9NUL3,O94966,O75190,Q9UNN5 27 +Mhc protein complex binding 0.679278058107464 1.832857914366783 0.066823703841836 1.0 0.3327067508181553 7 P08238,Q9NUQ9,P14618,P62258,P07900 5 +Cullin family protein binding 0.720030414799533 1.82596150728748 0.0678560601998858 1.0 0.3354822174062431 6 Q4G0X4,Q9NXV2,Q96GG9 3 +Trna binding 0.3876525900784427 1.8198837166651889 0.0687767151533131 1.0 0.3376745667596695 44 Q13325,Q9Y285,P49591,Q7Z4G4,Q9NXH9,Q9NX74,Q9UBP6,Q9HAV4,P38935,Q9H9T3,P05455 11 +Kinase regulator activity 0.3732842812744646 1.817754866266724 0.0691016077544481 1.0 0.3380957555875077 53 P05386,P36507,P49736,P61981,P42771,Q13043,P31946,Q02750,Q9H4A3,Q16543,Q9NX74,Q9H9T3,P08238,Q13177,P04792,Q92616,P60983,Q9UHD1,P46940,O95999,Q9UER7,Q9P287,O95067,P0DP25,Q9UNN5 25 +Hsp90 protein binding 0.5024035443012271 1.8085885257159893 0.0705149524155381 1.0 0.341466242176613 20 P31948,O94966,O95433,Q16543,P04150,Q9UHD1,P23396,P53041,Q00535 9 +Modified amino acid binding 0.4950841804972721 1.796376476937581 0.0724346623663039 1.0 0.3427401470950792 21 P00374,P28161,O43813 3 +Transforming growth factor beta receptor binding 0.7653313812408092 1.7960540217011218 0.0724859258341625 1.0 0.3427401470950792 5 Q96AC1,P62942,Q8WUH2 3 +Rna strand annealing activity 0.765277473054434 1.79582308201549 0.0725226585422444 1.0 0.3427401470950792 5 P23588,Q15056 2 +Trna methyltransferase activity 0.6302136122280384 1.7947499488880077 0.072693548482154 1.0 0.3427401470950792 8 Q9UBP6,Q7Z4G4,Q9NXH9 3 +Trna guanine methyltransferase activity 0.670020589145661 1.7886370970915575 0.0736732793742505 1.0 0.3460930798511302 7 Q9UBP6,Q7Z4G4,Q9NXH9 3 +Protein folding chaperone 0.4562487960928477 1.756007507290096 0.0790871267062325 1.0 0.3584269139827333 26 Q9H2J4,P04792 2 +Cysteine type exopeptidase activity 0.9094361671048844 1.7534678582035377 0.079521731993704 1.0 0.3589168084713347 2 Q0VDG4 1 +Dynein light intermediate chain binding 0.7536575564366867 1.7459468162763112 0.0808201937579431 1.0 0.3616447910561126 5 Q8TD16 1 +Protein serine threonine kinase activity 0.343764136751128 1.7433265959907942 0.0812765821963283 1.0 0.3625397073363039 85 Q8IV63,Q99570,P42345,P36507,P33981,Q13131,Q13043,P24941,P51617,Q99640,Q16512,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q9H2G2,Q14012,P17612,Q96KB5,P19525,P31751,O60566,P49841,O75116,P11274,Q13177,P78527,Q13546,Q99986,Q00535,O14874,Q96Q15,Q9UHY1,O95747,Q96SB4,Q9Y4B6,P10398,Q9NYV4,P19784,O14965,Q7Z460,P06493 45 +Cytoskeletal anchor activity 0.6536951095466402 1.7102508122627915 0.0872195032240878 1.0 0.3732372115109529 7 Q9UQB8,Q12955,Q8TD16 3 +Growth factor activity 0.7441905784289395 1.7051732704157576 0.0881621136100836 1.0 0.3732372115109529 5 Q9UMX5,P51858 2 +Molecular function inhibitor activity 0.5595493967051479 1.7024787045792602 0.0886656671771835 1.0 0.3742485175777237 12 P62942,O43768,Q9H4A3,P46934,Q96PU5 5 +Protein arginine n methyltransferase activity 0.6917357604707157 1.697584522806881 0.0895862059996335 1.0 0.3748986842922122 6 Q6P2P2,Q86X55 2 +Ubiquitin protein transferase inhibitor activity 0.6108222231976113 1.696029802575018 0.0898802361916972 1.0 0.3748986842922122 8 P62081 1 +5 3 exodeoxyribonuclease activity 0.894829097283093 1.6926312374205608 0.0905256813200918 1.0 0.3764803334900291 2 Q9UQ84 1 +Calmodulin binding 0.3837730324984553 1.6878268528385283 0.0914444712909254 1.0 0.3791861654116382 40 O43815,Q01844,P49006,O60869,Q5T4S7,Q14012,Q99439,Q15051 8 +Type i transforming growth factor beta receptor binding 0.9099941554646368 1.6841556000071205 0.0921516014348657 1.0 0.3798902753029161 3 Q96AC1,P62942 2 +Signaling adaptor activity 0.4859004453176019 1.6648774738403378 0.0959372031949721 1.0 0.3886968633744715 19 Q6SZW1,Q02750,Q96T76,P46109,P36507,Q06124,O60271,P46108 8 +Chemokine receptor binding 0.7342105263157935 1.6620627556525136 0.0965001922818302 1.0 0.3893763169503652 5 P54577,O43776,P48681,Q96J02 4 +Channel regulator activity 0.4937196594137092 1.6559889270396797 0.0977240612418572 1.0 0.3925619960113244 17 P62942,O43768,Q9H4A3,Q04917,Q9UHD1,Q9UKS6,P46934,Q96PU5 8 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.767793986808657 1.6529855840743628 0.0983337975182685 1.0 0.393239465840188 4 Q13614,Q8NCE2 2 +Metal dependent deubiquitinase activity 0.6410177932932837 1.6490469955830227 0.0991380072177339 1.0 0.393239465840188 7 Q92905,P51665 2 +Potassium channel regulator activity 0.637236765690925 1.6307398199241243 0.1029452305440479 1.0 0.4020233610256409 7 O43768,Q9H4A3,Q96PU5 3 +Ribose phosphate diphosphokinase activity 0.7617655656240923 1.6276957311914342 0.1035894187151611 1.0 0.4020233610256409 4 P11908,Q14558,P60891 3 +Diphosphotransferase activity 0.7617655656240923 1.6276957311914342 0.1035894187151611 1.0 0.4020233610256409 4 P11908,Q14558,P60891 3 +Amide transmembrane transporter activity 0.5967980281892628 1.62414853598361 0.1043441113835998 1.0 0.4020233610256409 8 Q9H2D1 1 +Ubiquitin like protein ligase activity 0.3555581508561426 1.6180867609154046 0.1056439012336651 1.0 0.4059252074576157 52 P19474,O95155,P98170,Q14527,Q9Y314,Q8IYU2,Q9C0C9,O75448,Q5T4S7,Q9H1B7,Q96J02,Q15386,Q7Z6Z7,P46934,Q8TDB6,Q96PU5 16 +Growth factor receptor binding 0.4845460367849125 1.5968155960680224 0.110306818400798 1.0 0.4170423561998087 17 Q9H2J4,Q13596 2 +Mhc class ii protein complex binding 0.6692702958905277 1.5947653122989247 0.1107647266422686 1.0 0.4172541422605041 6 P14618,P62258,P08238,P07900 4 +Cadherin binding involved in cell cell adhesion 0.550946800399637 1.593329430400395 0.1110863077437556 1.0 0.4172541422605041 11 Q9UQB8,P04083,Q15417 3 +Ubiquitin like protein transferase activity 0.3315361540291668 1.591599969488381 0.1114746169540032 1.0 0.4172541422605041 73 Q93034,O95155,P98170,P61081,Q5T4S7,Q5W0B1,Q96J02,Q86UK7,Q8TBC4,Q8N806,Q7Z569,P19474,Q14527,Q16763,Q9H1B7,O75448,Q96PU5,O75150,Q9C0C9,P68036,Q15386,Q9NZJ0,Q7Z6Z7,Q9NT62,P46934,Q8TDB6,P49427,Q9UII4,Q9Y314,Q8IYU2 30 +Protein methyltransferase activity 0.412251005444566 1.5912950666683503 0.1115431865448872 1.0 0.4172541422605041 29 Q9UI30,Q6P2P2,Q86X55,O96028,Q9UBL3,Q9BV86 6 +Tau protein binding 0.4725523417285446 1.576125149956803 0.1149969640374819 1.0 0.4234052403526466 19 P08238,P49841,O75116,Q14203,Q13526,Q02790,P78559,P53041,P07900,Q00535 10 +Exopeptidase activity 0.3861657701546975 1.5753044322258252 0.1151861914204923 1.0 0.4234052403526466 32 Q6P179,Q86TI2,P42785,Q9H3G5,Q0VDG4,Q12765 6 +Proline rich region binding 0.6649435353298627 1.5748823428723122 0.1152836050465127 1.0 0.4234052403526466 6 Q9UQB8,P46934 2 +Tbp class protein binding 0.6242621643251516 1.56774612387689 0.1169403927978365 1.0 0.4254663852687305 7 O14981,O75155,P62195,Q86VP6 4 +Endonuclease activity 0.3719717688998827 1.557104832133312 0.1194455979817097 1.0 0.4312823465221445 39 Q96F86,Q9UQ84,Q8N2A8,Q9BQG2,Q9Y2L1,Q9UPY3,P23396,Q15631,Q99598,P39748 10 +Rna cap binding 0.5271584797382176 1.5196462844312306 0.1285998986154433 1.0 0.4523389468712359 12 O15371,Q13325,Q6PKG0,P06730,Q96C86,P60842 6 +Ubiquitin like protein conjugating enzyme activity 0.6505380547852707 1.5085186313291812 0.1314218418885233 1.0 0.4581159652510254 6 Q9C0C9,P49427,P68036 3 +Smad binding 0.4876319033306533 1.5076137595717585 0.1316534090845569 1.0 0.4581159652510254 15 Q96AC1,Q9H6Z4,P62942,Q8WUH2 4 +Pentosyltransferase activity 0.4992152812814151 1.5008518890786218 0.1333938742431657 1.0 0.4581159652510254 14 Q06203,Q13126 2 +Protein serine threonine kinase inhibitor activity 0.5728499165868737 1.5005771520549789 0.1334649645486907 1.0 0.4581159652510254 8 P04792 1 +Kinase inhibitor activity 0.4547203214270185 1.4872203735432723 0.1369566168264839 1.0 0.4632934358675797 20 Q9H4A3,P61981,P42771,Q9NX74,P04792,P60983,Q9UHD1,P31946 8 +Protein kinase a binding 0.4521885252772263 1.4699935044965955 0.1415635132087298 1.0 0.4695814600945143 20 Q02952,P49841,Q96M27,Q9H3P7,P15311,P35241,P17612,O43823,P23396 9 +Hydrolase activity hydrolyzing n glycosyl compounds 0.5468203284257296 1.4581166019394296 0.1448084060308492 1.0 0.4750790861429717 9 O43598,Q6SZW1,P27695,P13051,Q16706,P23396 6 +Intramolecular transferase activity phosphotransferases 0.6865592788282375 1.4547065631847975 0.1457505148402829 1.0 0.4755848321550706 5 Q96G03,P18669 2 +Potassium channel inhibitor activity 0.8483343074225602 1.444419745280206 0.1486209398166587 1.0 0.4793501004431332 3 Q9H4A3,Q96PU5 2 +Phosphatase inhibitor activity 0.5613349204638177 1.4408469056659257 0.1496279386511427 1.0 0.4793501004431332 8 Q96C90,Q01105,Q9BTT0,O43768 4 +Protein kinase activity 0.3118089840838333 1.4400993897101215 0.1498392817509652 1.0 0.4793501004431332 103 Q8IV63,Q99570,P42345,P36507,P33981,Q13131,Q13043,P24941,P51617,Q99640,Q16512,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q9H2G2,Q14012,P17612,Q96KB5,P19525,P31751,O60566,P49841,Q8NEB9,O75116,P11274,Q13177,Q13263,P78527,P22392,Q13546,Q99986,Q00535,O14874,P41240,Q96Q15,Q9UHY1,O95747,Q96SB4,Q9Y4B6,P10398,Q9NYV4,P19784,O14965,Q7Z460,P06493 49 +Sh3 domain binding 0.4132034337187405 1.430286726903554 0.1526347427123688 1.0 0.4860935274668684 26 Q96JJ3,O43813,P50570,Q9UJC5,Q96T51,P40818,Q16204,O15357,Q14195,Q9NZQ3,P46108,Q8N8S7,Q9Y5K6 13 +Phosphatidylinositol 5 phosphate binding 0.714585865534485 1.4286859214051806 0.1530945260628502 1.0 0.4864130354463265 4 A1X283,Q9Y5X3 2 +Calcium channel regulator activity 0.7126571178018319 1.4205190664766882 0.1554566218174424 1.0 0.4906599626113028 4 Q9UKS6,P62942,P30626 3 +Protein phosphorylated amino acid binding 0.4562057353393912 1.4127558746270332 0.1577275164944316 1.0 0.4923326894550249 17 Q92541,P46109,P07737,Q13526,P46108,P46934,P31946 7 +Metallopeptidase activity 0.3523559097240241 1.4094278428498102 0.1587086959147945 1.0 0.4932177934582845 41 Q6P179,P51665,O43847,Q7L5N1,Q96KP4,Q96E52,Q92905,Q9HD42 8 +Protein kinase a catalytic subunit binding 0.5900088507932522 1.4003586293911223 0.1614059520857469 1.0 0.4960433350917247 7 P49841,P15311 2 +Calcium channel inhibitor activity 0.8247151621384857 1.3993009451265426 0.1617227563488579 1.0 0.4960433350917247 2 P62942 1 +N methyltransferase activity 0.38724603418985 1.3876166504751055 0.1652538085349792 1.0 0.5035967354923722 29 Q86TU7,Q7Z4G4,Q9NXH9,Q6P2P2,Q86X55,O96028,Q9UBL3,O60678 8 +Proteasome binding 0.5103031247024845 1.3669691524803156 0.1716349746714724 1.0 0.5171939640522499 11 O95456,Q92995,P54725 3 +Protein tyrosine phosphatase activity 0.4453681381755548 1.366963712166657 0.171636679981197 1.0 0.5171939640522499 18 Q9UNI6,O60942,Q13614,Q99504,Q06124,P51452,Q8NCE2 7 +Fk506 binding 0.5824994974139015 1.3635028258599524 0.1727240944737456 1.0 0.5171939640522499 7 Q02790,Q96AY3,P62942,Q00688 4 +Macrolide binding 0.5824994974139015 1.3635028258599524 0.1727240944737456 1.0 0.5171939640522499 7 Q02790,Q96AY3,P62942,Q00688 4 +Transferrin receptor binding 0.6987153816189919 1.3614441698846131 0.1733733656016736 1.0 0.5171939640522499 4 Q13596 1 +Endodeoxyribonuclease activity producing 5 phosphomonoesters 0.617767622538835 1.3567946985405082 0.1748464524794899 1.0 0.5193916226304099 6 Q9UQ84,Q9UPY3 2 +Pre mirna binding 0.6639386215480326 1.355642370798951 0.1752129836751899 1.0 0.5193916226304099 5 Q9UPY3,Q9HAV4,P62826 3 +5 3 exonuclease activity 0.5275354847712055 1.3544923691927324 0.1755793462640282 1.0 0.5193916226304099 9 Q8IV08,Q9UQ84,Q9BQ61 3 +Oxygen sensor activity 0.8121530820917442 1.3467216535351898 0.1780698956838378 1.0 0.5211905098052451 2 O75306 1 +Sodium channel regulator activity 0.6944980370642622 1.3435637239929314 0.17908950666326 1.0 0.5211905098052451 4 Q96PU5 1 +Proteasome activating activity 0.6148864520000414 1.3434194243126514 0.1791362006827079 1.0 0.5211905098052451 6 P62195,P62191,P17980,P62333 4 +Cyclin dependent protein serine threonine kinase regulator activity 0.6135257099937428 1.3371011279795677 0.1811896290534305 1.0 0.5217519403545465 6 O95067 1 +Peptide alpha n acetyltransferase activity 0.6592424781007536 1.3350488524066286 0.1818603579910021 1.0 0.5217519403545465 5 P41227,Q86UY6,Q9BXJ9 3 +Udp glucosyltransferase activity 0.6924526477583287 1.3348907733581603 0.1819120980161184 1.0 0.5217519403545465 4 P46976 1 +Map kinase scaffold activity 0.657596388979848 1.3278290866459703 0.1842345756348229 1.0 0.5252171168299186 5 P36507,O60271,Q02750 3 +Signaling receptor complex adaptor activity 0.5738297121445486 1.3209053608947012 0.1865329220391067 1.0 0.5290386791222456 7 P46108,Q06124,O60271,Q96T76 4 +Isopeptidase activity 0.537988244018999 1.3192915289932794 0.1870716687136653 1.0 0.5290386791222456 8 Q92905,P51665 2 +Intramolecular oxidoreductase activity interconverting aldoses and ketoses 0.6545671289735858 1.3145413226491751 0.1886641015926493 1.0 0.5314164136494147 5 P06744,P34949 2 +Small protein activating enzyme binding 0.8123904149620138 1.304273938774342 0.1921401977529229 1.0 0.5346987770608242 3 Q9UBE0,Q9UBT2 2 +Small molecule sensor activity 0.8123904149619994 1.3042739387742854 0.1921401977529422 1.0 0.5346987770608242 3 P54727,O75306 2 +Nedd8 specific protease activity 0.8085714567329825 1.289397414523461 0.1972599598105844 1.0 0.5416030741207114 3 Q96FW1 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.6469897244633124 1.2812985986448011 0.2000888049310138 1.0 0.5443625726136263 5 Q13614,Q8NCE2 2 +Fibroblast growth factor binding 0.6780853860450995 1.2739656000929829 0.2026756077622715 1.0 0.5443625726136263 4 P15880,Q9BZZ5 2 +Gdp dissociation inhibitor activity 0.5995838260470279 1.2723309030501089 0.2032555730497258 1.0 0.5443625726136263 6 P55010,Q86YR5,P50395 3 +Dna helicase activity 0.3396235449592995 1.2696431217955575 0.2042117817161384 1.0 0.5443625726136263 40 Q9H4L7,P46063,Q12873,Q8N3C0,Q86WJ1,P49736,P40938,P40937,Q9HCK8,P25205,P13010,P38935,Q13283,P13984,O14646,P33991,Q9Y620 17 +Phosphatase activator activity 0.5267401023346943 1.2605919339752654 0.2074559062272956 1.0 0.5443625726136263 8 Q15257,P35269,O94766,Q14738,P0DP25 5 +Deoxyribonuclease activity 0.4249727199062125 1.256884553180645 0.2087954427039065 1.0 0.5443625726136263 19 P15531,Q8IV08,Q9UQ84,Q9UPY3,P23396,P39748 6 +Glutathione peroxidase activity 0.5961121611571839 1.2561972393517122 0.209044467418104 1.0 0.5443625726136263 6 P28161 1 +Kinesin binding 0.4889659842686444 1.2474335426088157 0.212238573921047 1.0 0.5503724590816651 11 Q96EK5,O60271,Q9NPI6 3 +Phosphatidylinositol kinase activity 0.6715398107890211 1.2462161126817488 0.2126850652163465 1.0 0.5503724590816651 4 P42356 1 +Histone methyltransferase activity 0.4148306020201801 1.2435493176346812 0.2136654792801249 1.0 0.5506384624612022 21 Q86X55,O96028,Q9UBL3 3 +Exodeoxyribonuclease activity 0.5068896124058873 1.243208450176802 0.2137910296260254 1.0 0.5506384624612022 9 Q8IV08,Q9UQ84,P39748 3 +Protein phosphatase activator activity 0.592054656145997 1.2373411206111593 0.2159604678454041 1.0 0.5542070808228701 6 Q14738,Q15257,P0DP25 3 +Cytokine binding 0.5878603495163377 1.2178511603501028 0.2232805386738618 1.0 0.5624368205125215 6 P09429,Q92905 2 +Dynein light chain binding 0.7806018112766678 1.2150535300855194 0.2243456756153778 1.0 0.5624552931208233 2 Q86VS8 1 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.7884717383316628 1.2112161733697928 0.2258125657817697 1.0 0.5651309168414558 3 Q9Y223 1 +Chemoattractant activity 0.6599758014462069 1.1972260407732844 0.2312184625264155 1.0 0.5695072245317108 4 P09429,P14174 2 +Amidine lyase activity 0.6597514045746002 1.1962760178511125 0.2315888642897692 1.0 0.5695072245317108 4 Q8WUX2 1 +Cxcr chemokine receptor binding 0.775343266140823 1.1931955310517013 0.2327928044769356 1.0 0.5714740026569218 2 Q96J02 1 +Single stranded dna exodeoxyribonuclease activity 0.6260575953577722 1.189500709426398 0.2342426920138711 1.0 0.5740366837220343 5 Q8IV08,Q9UQ84 2 +Serine hydrolase activity 0.4138166365383979 1.181814989430391 0.237279118843807 1.0 0.5763263553090326 19 Q86TI2,Q4J6C6,Q9H3G5 3 +Dynein heavy chain binding 0.7808299240210443 1.1815624730733052 0.2373793511492983 1.0 0.5763263553090326 3 O43237,Q9Y6G9 2 +Ribosomal small subunit binding 0.4672337232012936 1.1776329561905212 0.2389429654528987 1.0 0.5763263553090326 12 P15531,P23588,Q15056 3 +Actin monomer binding 0.5789281758971938 1.1763613744995016 0.2394504997759476 1.0 0.5763263553090326 6 P07737,P35080 2 +Molecular function regulator 0.3237808528452308 1.1759995721990777 0.2395950470091796 1.0 0.5763263553090326 328 Q14558,P30153,Q14232,O43768,P25685,P30086,Q9UMX5,P61201,Q13200,Q13043,Q86YR5,Q9HC52,Q9NR50,P04083,Q96HP0,Q14738,P31689,P14174,A1X283,Q15435,P30740,Q96PU5,Q96C90,Q99615,P04792,Q9C0C9,Q9UHD1,Q9UKS6,Q15042,P46934,P43490,Q00535,Q8TC07,O95067,Q13144,Q66K14,P0DP25,P62942,Q99497,P98170,P36507,Q5H9R7,P51617,P55145,Q01105,P30154,Q8TF05,Q9H6Z4,Q9NY27,Q9H6U6,P07737,Q9P258,Q9NZL9,Q9H9T3,P78318,P08238,P20810,Q15437,O95817,Q13177,O14737,P68036,P61289,Q96QE5,Q8TDB6,Q15257,P62081,Q9BTT0,Q04917,P55010,O75190,P51858,P17931,O95433,P42771,Q4KMP7,Q15008,Q99460,Q6NYC1,P80303,P09429,P62841,Q16543,O60256,P13010,P19525,O43924,P30626,P04080,P06744,P29692,O60343,Q01968,P49770,P63151,Q9P287,Q9Y2L1,Q15436,O43242,Q5VZ89,Q99543,Q9UBE0,Q9NVG8,O95429,P31946,Q02750,Q9H4A3,Q9NX74,Q9Y4F1,O95373,Q9UL46,O95999,O60884,Q8N6T3,Q9NPI6,Q9UNN5 116 +Endopeptidase activator activity 0.6228703134904845 1.1755366795589013 0.2397800715475981 1.0 0.5763263553090326 5 Q9UL46,P61289 2 +Protein kinase c activity 0.6213742895828986 1.168984358185197 0.2424099334855687 1.0 0.5775356796611827 5 Q96Q15 1 +Tpr domain binding 0.6529387006444718 1.1674479487761036 0.2430295170692546 1.0 0.5775356796611827 4 P08238,O76094 2 +Transferase activity transferring one carbon groups 0.2944196785987176 1.1659820025547896 0.243621722129403 1.0 0.5775356796611827 68 Q9HCE5,Q9UI30,Q86TU7,Q7Z4G4,Q9NXH9,O60678,Q9UBP6,Q6P2P2,Q9HBK9,Q86X55,O96028,Q9UBL3,Q9BV86,Q8IZ69,Q96P11 15 +Protein kinase a regulatory subunit binding 0.4822079013360796 1.1585686692687427 0.2466320459270341 1.0 0.5805332709196711 10 O43823,Q96M27,Q9H3P7,P15311 4 +Endodeoxyribonuclease activity 0.4634954345601595 1.15627597960938 0.2475682902153901 1.0 0.5805332709196711 12 Q9UQ84,Q9UPY3,Q96QE5,P23396,P39748 5 +Amp binding 0.5057432928152896 1.1509893154514268 0.2497366311804971 1.0 0.5813374620677401 8 P06737,P08237,P07741,Q01813,P11908 5 +Structural constituent of muscle 0.6165338018647449 1.1477940274581993 0.2510536034928146 1.0 0.5813374620677401 5 Q16527 1 +Metalloendopeptidase activity 0.4187219065909447 1.147299895654187 0.251257697136753 1.0 0.5813374620677401 16 O43847,Q92905,Q96E52 3 +Alpha tubulin binding 0.5690281847908163 1.1304230718239874 0.2582979968501711 1.0 0.5903985531815862 6 Q15813,Q9P265 2 +Small ribosomal subunit rrna binding 0.5689473214504033 1.1300481317107045 0.2584559437195204 1.0 0.5903985531815862 6 Q14011,P62277 2 +Single stranded dna binding 0.2960305615540753 1.1209414308819006 0.2623127938233316 1.0 0.5934564647459054 63 P09429,Q96FZ2,Q99497,Q92541,Q7L590,Q9NYB0,Q9Y3Z3,P35244,P54727,P15927,Q9H1E3,P38935,P54725,Q15365,Q96AE4,P67809,Q15631,P33991 18 +Structural constituent of postsynapse 0.6088034433587465 1.113991257879115 0.2652829370743457 1.0 0.5944692123979791 5 Q16352,P12814,P07196 3 +Dna apurinic or apyrimidinic site endonuclease activity 0.7630040911747491 1.112606448162488 0.2658774898699265 1.0 0.59485881436088 3 P23396,Q96FZ2 2 +Lysine n methyltransferase activity 0.4224866973526591 1.101307841915865 0.2707626993292722 1.0 0.600725849931713 15 Q9UBL3 1 +Histone lysine n methyltransferase activity 0.4224866973526591 1.101307841915865 0.2707626993292722 1.0 0.600725849931713 15 Q9UBL3 1 +Gtpase activating protein binding 0.6056596362778249 1.1002604661898905 0.2712186518971062 1.0 0.600725849931713 5 P07437,Q13526 2 +Cadherin binding 0.2851621473395404 1.0985020247838049 0.2719853339973015 1.0 0.600725849931713 206 Q16658,Q9Y6E2,Q15691,O75874,P13639,P25685,Q06124,P78344,Q14258,P04083,Q9H2G2,Q9H3U1,Q9UQB8,P18206,Q9BPX3,P47914,Q99439,O60763,Q8WWM7,Q8NC51,P28072,O95067,Q96TA1,Q14247,Q15365,Q9NUQ8,Q9H4M9,Q99961,Q8TCG1,Q9UGI8,Q99497,P26196,Q5T6F2,P15311,P15880,P62826,Q12792,P61978,Q8WU90,P42356,Q9NZZ3,Q15056,P07737,P08238,P20810,P26641,P53990,P83731,Q13177,O95817,P62750,Q9NTK5,P55010,Q9UBC2,O95433,Q12955,Q9Y266,O60664,Q13596,P14618,P46109,P29692,Q92616,P63104,O60749,O00299,P60228,P42224,Q15417,P31939,Q14677,P31946,Q6PKG0,Q9UHD8,Q9UNF0,Q9H223,Q15019,P00338,P40818,P35241,P62258,Q9Y5X3,P46940,P30041,P35613,Q96HC4,Q7L1Q6,Q6IBS0,Q9HC38,Q9UHB6,Q9Y5K6 91 +1 4 alpha oligoglucan phosphorylase activity 0.7584427710600784 1.0950211016883078 0.2735073918998316 1.0 0.600725849931713 3 Q13126 1 +Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 0.7574359205481516 1.0911431090223098 0.275209916469654 1.0 0.6013283822928257 3 Q8NCE2 1 +Glucocorticoid receptor binding 0.7502191060473267 1.0892893251593805 0.2760263186771698 1.0 0.6013283822928257 2 Q04917 1 +Ribonuclease p rna binding 0.7499269646508899 1.0880872342010388 0.2765565987774727 1.0 0.6013283822928257 2 Q99575 1 +S adenosylmethionine dependent methyltransferase activity 0.3055663967587146 1.082474490065484 0.2790417446438991 1.0 0.6042343444509545 51 Q9HCE5,Q86TU7,Q7Z4G4,Q9NXH9,O60678,Q9UBP6,Q6P2P2,Q9HBK9,Q86X55,O96028,Q9UBL3,Q96P11 12 +Nucleoside diphosphate kinase activity 0.5565217433015981 1.072509268810253 0.2834913530558678 1.0 0.6118984802465846 6 P15531,P22392 2 +Rna methyltransferase activity 0.3768956860349468 1.072329704923975 0.2835719691192071 1.0 0.6118984802465846 24 Q9HCE5,Q86W50,Q7Z4G4,Q9NXH9,Q9UBP6,Q8IZ69,Q96P11 7 +Microtubule plus end binding 0.4572413965401426 1.069862736166606 0.2846810984280936 1.0 0.6126926532379366 11 Q15691,Q15555,P43034,Q14203,O75122 5 +Protein arginine omega n monomethyltransferase activity 0.7495616598480555 1.0608648299552537 0.288751334557066 1.0 0.6175705479252409 3 Q6P2P2,O60678 2 +Protein arginine omega n asymmetric methyltransferase activity 0.7495616598480492 1.0608648299552297 0.2887513345570769 1.0 0.6175705479252409 3 O60678,Q86X55 2 +Protein phosphatase 2a binding 0.4642183758274354 1.0599186568586318 0.28918160711217 1.0 0.6175705479252409 10 Q9P2B4,O43815,Q15257,O43768,P78318 5 +Intramolecular transferase activity 0.4428704878288059 1.0387776973979832 0.2989081360796 1.0 0.6226813519202057 12 Q96G03,P18669,P36871,Q8WWH5,Q96PZ0 5 +Nuclease activity 0.2856468039524489 1.0339031606292657 0.3011814372981476 1.0 0.6226813519202057 73 P15531,Q96F86,Q96C86,Q8IV08,Q9UQ84,Q9BQ61,Q8N2A8,Q9Y3Z3,Q9BQG2,Q9Y2L1,Q9UPY3,Q9HB07,P23396,Q15631,Q99598,P39748 16 +Transferase activity transferring alkyl or aryl other than methyl groups 0.380498823976264 1.0330608299652493 0.3015754325199524 1.0 0.6226813519202057 22 P28161,O43813 2 +Deoxynucleoside kinase activity 0.7353198948291045 1.0282036697867691 0.3038540325511421 1.0 0.6226813519202057 2 P04183 1 +Kinase activator activity 0.3906298145904699 1.0263868107634746 0.3047092924323544 1.0 0.6233760568588376 19 Q02750,O95999,Q9UER7,Q9H4A3,P36507,Q13177,Q13043,P0DP25,P46940 9 +Ribonuclease activity 0.3021338059557044 1.0256106864415204 0.3050751282505768 1.0 0.6233760568588376 48 Q96F86,Q96C86,Q9UQ84,Q8N2A8,Q9Y3Z3,Q9BQG2,Q9Y2L1,Q9UPY3,Q99598 9 +Phosphatidylinositol phosphate phosphatase activity 0.5133959851159531 1.024162660310088 0.3057584521136687 1.0 0.6233998846628226 7 Q13614,Q8NCE2 2 +Beta catenin binding 0.3964834740821795 1.0229511029076614 0.306330965562033 1.0 0.6233998846628226 17 Q86X55,Q9UBL3 2 +Ccr5 chemokine receptor binding 0.7335670464504809 1.0210492170939216 0.3072311212158041 1.0 0.6241735709757859 2 P48681 1 +Mrna methyltransferase activity 0.510643670355833 1.010732130064483 0.3121446546074886 1.0 0.6271398037785482 7 O43148,Q9HCE5,Q86U44,Q86W50,Q8N1G2 5 +Nedd8 transferase activity 0.7303534910896861 1.0079519586048298 0.3134775260230573 1.0 0.6287336479384441 2 P61081 1 +Nucleocytoplasmic carrier activity 0.3796900614108044 1.000631597827555 0.3170049480209802 1.0 0.6305769419579221 21 Q92973,Q9Y5L0,P52294,Q9UIA9,P55060,Q9HAV4,Q9C0E2,P62826,O00505,O60684 10 +Ccr chemokine receptor binding 0.733781414377557 1.0004923844523566 0.3170722812815294 1.0 0.6305769419579221 3 P48681,O43776 2 +Structural constituent of cytoskeleton 0.3159584556053585 0.9951768824816992 0.3196502431566863 1.0 0.6339206785744101 36 O60504,O15144,P07197,P26038,O15145,Q9BVA1,Q16352,P08670,P04350,P23258,Q12955,Q16204,Q9BUF5,Q9UEY8,P07196,Q9Y2J2,P07437,Q9Y5K6 18 +Cis trans isomerase activity 0.3389001420728432 0.9939691311008276 0.3202378960526184 1.0 0.6341966176728325 29 Q96AY3,P62942,Q5T1M5 3 +Phosphatidylinositol monophosphate phosphatase activity 0.6107225307742954 0.9899010759507378 0.322222473555565 1.0 0.6354568725349635 4 Q8NCE2 1 +Serine type carboxypeptidase activity 0.5791062558987349 0.9848208087056212 0.3247120974997477 1.0 0.6393469167442256 5 Q9H3G5 1 +Nuclear export signal receptor activity 0.4730108486705797 0.9808723755559292 0.3266556815994814 1.0 0.6400905989940556 8 P62826,Q9UIA9,P55060,Q9HAV4,Q9C0E2 5 +Histone threonine kinase activity 0.6084244234534554 0.9803162840279572 0.3269300190517956 1.0 0.6400905989940556 4 Q16512,Q9Y4B6 2 +Phosphoserine residue binding 0.5032798176738398 0.9748738561922148 0.3296228358611364 1.0 0.6419661964319741 7 P46934,Q92541,Q13526 3 +Nucleoside triphosphatase regulator activity 0.2825657065559526 0.973986499729007 0.3300632424370899 1.0 0.6419661964319741 91 Q5VZ89,Q14232,Q9NVG8,P80303,Q86YR5,Q9NR50,Q96HP0,Q9H6Z4,Q9Y4F1,O43924,O95373,Q15437,P29692,O60343,Q01968,Q15042,P49770,Q8TC07,Q9Y2L1,Q8N6T3,P55010,Q13144,Q15436 23 +Gtp dependent protein binding 0.4714617843196858 0.9728694845347968 0.3306181730134971 1.0 0.6421622206608311 8 Q15075,P61020,Q86YV9,O00203,O00429,O43747 6 +Adenyl nucleotide exchange factor activity 0.4703608154883351 0.9671852484916472 0.3334514351861801 1.0 0.6423074377213153 8 P07737,O95817 2 +Atpase regulator activity 0.4703608154883351 0.9671852484916472 0.3334514351861801 1.0 0.6423074377213153 8 P07737,O95817 2 +Mutlalpha complex binding 0.605113328186083 0.9665261460710648 0.3337809702017513 1.0 0.6423074377213153 4 Q13535,P52701 2 +Mismatch repair complex binding 0.605113328186083 0.9665261460710648 0.3337809702017513 1.0 0.6423074377213153 4 Q13535,P52701 2 +Enzyme regulator activity 0.2997612929338825 0.9663427960850072 0.333872678023456 1.0 0.6423074377213153 266 Q14558,P30153,Q14232,O43768,P30086,P61201,Q13200,Q13043,Q86YR5,Q9HC52,Q9NR50,P04083,Q96HP0,Q14738,A1X283,Q15435,P30740,Q96C90,Q9C0C9,P04792,Q9UHD1,Q15042,Q8TC07,O95067,Q13144,Q66K14,P0DP25,Q99497,P98170,P36507,Q5H9R7,P51617,Q01105,P30154,Q8TF05,Q9H6Z4,Q9NY27,Q9H6U6,Q9P258,Q9NZL9,Q9H9T3,P78318,P08238,P20810,Q15437,Q13177,O14737,P68036,P61289,Q96QE5,Q8TDB6,Q15257,P62081,P55010,P42771,P80303,P62841,Q16543,O43924,P04080,P29692,O60343,Q01968,P49770,P63151,Q9P287,Q9Y2L1,Q15436,O43242,Q5VZ89,Q9UBE0,Q9NVG8,P31946,Q02750,Q9H4A3,Q9NX74,Q9Y4F1,O95373,Q9UL46,O95999,Q8N6T3,Q9NPI6,Q9UNN5 83 +Phosphatidylinositol 3 5 bisphosphate binding 0.5316532776673537 0.9580239229347698 0.3380506954398239 1.0 0.6450791948068973 6 A1X283,Q9Y5X3 2 +H4 histone acetyltransferase activity 0.7220923436586808 0.9560849297907557 0.3390293279173804 1.0 0.6460747569746306 3 Q86UY6,O14929 2 +Cyclin dependent protein kinase activity 0.4678939570185724 0.9544605796561452 0.3398505542226857 1.0 0.6467680803107371 8 Q00534,Q00535,Q9NYV4,P24941,P06493 5 +Phosphotyrosine residue binding 0.4409431605464202 0.93318193028505 0.3507260427649878 1.0 0.6594768942416128 10 P46108,P07737,P46109 3 +Serine type exopeptidase activity 0.4938668110659738 0.9292248925533872 0.3527725496100991 1.0 0.6615654975446685 7 Q9H3G5 1 +Phosphatidylinositol bisphosphate binding 0.3607403214039702 0.9225317191283288 0.3562512931522126 1.0 0.6654416492962069 23 Q9BPX3,O60493,P07737,P35080,Q6IBS0,A1X283,Q9Y5X3 7 +Phosphatidylinositol 3 phosphate binding 0.491656211735901 0.9185396723813956 0.3583363990222779 1.0 0.6682857400542217 7 Q96L92,A1X283,O60493 3 +Protein serine threonine kinase activator activity 0.4363598011617218 0.9084141281938511 0.3636594640733612 1.0 0.6714060027007273 10 P0DP25,Q02750,Q13043 3 +Cysteine type peptidase activity 0.2885864949717674 0.907405034937098 0.3641926478581738 1.0 0.6714060027007273 51 Q01804,Q96K76,P51665,Q96FW1,Q92995,Q7L5N1,P40818,Q14674,Q0VDG4,Q12765,O94966,Q92905 12 +Low density lipoprotein particle receptor binding 0.4270631694109251 0.9026421828428824 0.3667158310563705 1.0 0.6736746600194592 11 O43813,Q15036 2 +Gtpase binding 0.2723640218601573 0.8970853834509879 0.3696733575710129 1.0 0.6764917027387607 103 Q9UJY5,O43592,Q9NVG8,Q9HAV4,Q16512,P67809,Q92973,Q9Y496,P07737,Q9P258,Q9Y4F1,Q8TD16,O43924,O95373,P16989,Q86YV9,Q8IWJ2,P55060,Q13177,Q9NUQ9,Q27J81,Q01968,Q15042,Q9Y5L0,O15397,Q9UIA9,O60879,P07900,Q8IYU2 29 +Ubiquitin protein transferase regulator activity 0.4171251517368531 0.8936408008749023 0.3715141087632965 1.0 0.6771939761180858 12 P62081,Q9HC52,P62841 3 +Molecular function activator activity 0.3981983378872514 0.8917310769543608 0.372537092113232 1.0 0.6771939761180858 14 O95433,Q99543,O60884,P25685,Q99615,P31689,Q6NYC1 7 +Phosphodiesterase i activity 0.7005550686532303 0.8878890352677149 0.3746004433312133 1.0 0.6771939761180858 2 P27695 1 +Intermediate filament binding 0.5860301088754978 0.8875654585542968 0.3747745407526008 1.0 0.6771939761180858 4 P08670,P48681 2 +Actinin binding 0.5541868853644911 0.8777891801336885 0.380058137271553 1.0 0.6819824950532689 5 Q16527 1 +Rna polymerase iii transcription regulatory region sequence specific dna binding 0.7005333853885288 0.8750487837654937 0.3815473625370593 1.0 0.682979618107937 3 P42345 1 +Enzyme inhibitor activity 0.2746577556461561 0.8749890877191291 0.3815798432144768 1.0 0.682979618107937 81 Q14558,P98170,O43768,P30086,P42771,P61201,P31946,Q01105,P62841,Q9H4A3,P04083,Q9NX74,P30740,O43924,P04080,Q96C90,Q9C0C9,P04792,P62081 19 +Glucuronosyltransferase activity 0.6990064289888862 0.8693583091013127 0.3846511790167439 1.0 0.6858723419037528 3 O43505,Q93063 2 +Transferase activity transferring phosphorus containing groups 0.2727355508593728 0.8608850443196424 0.3893013594598506 1.0 0.6924177638694702 209 Q14558,P08237,P04183,Q13043,Q9HA64,P35790,Q16539,Q5TAX3,Q9HBU6,Q14012,Q07864,P49642,P78356,Q13546,Q00535,O14874,O60942,Q96Q15,P12277,P10398,Q9UKK9,Q7Z460,Q9NVU0,Q99570,P36507,P23919,P24941,P51617,P60891,P48729,P42356,Q13535,Q96KB5,P15531,P31751,Q13177,Q9Y3D8,P13807,Q9NRN7,Q9UHY1,Q9Y4B6,O14965,P42345,P33981,Q96IJ6,Q99640,Q16512,P51003,O60256,P14618,P17612,P19525,P51570,Q8NEB9,Q9NVE7,P22392,Q99986,Q96SB4,Q9UJ70,Q9Y223,P19784,O95747,P11908,P06493,Q8IV63,P55263,P49903,Q00534,Q02750,Q13572,Q16222,Q9H4A3,Q9BRR6,Q9P289,P49841,O75116,Q13263,P78527,P41240,P56282,Q9NQX3,Q9NYV4,Q16851 83 +Phosphatidylinositol transfer activity 0.6926672509494768 0.8566018443905928 0.3916649660584888 1.0 0.6931342453150227 2 Q00169 1 +Phospholipid transfer activity 0.6926672509494768 0.8566018443905928 0.3916649660584888 1.0 0.6931342453150227 2 Q00169 1 +Phosphatidylcholine transfer activity 0.6926672509494768 0.8566018443905928 0.3916649660584888 1.0 0.6931342453150227 2 Q00169 1 +Phosphotransferase activity phosphate group as acceptor 0.4003943790616161 0.8504340634719276 0.3950838045969731 1.0 0.6974388260925344 13 P15531,P22392,Q9Y3D8 3 +Phosphotransferase activity nitrogenous group as acceptor 0.5765641051687338 0.8487842444056064 0.3960013588070048 1.0 0.6981869343554923 4 P22392 1 +Racemase and epimerase activity 0.575026552224525 0.8425129489631246 0.3995008946693148 1.0 0.7008595115988634 4 Q9Y223 1 +Amide binding 0.2647544979050465 0.83481728370887 0.4038205928879621 1.0 0.7042271755604502 108 Q9BYT8,Q9NQP4,P24390,Q96AY3,P00374,Q6P179,O43813,P62942,O15212,Q9UHV9,P52294,Q15392,P28161,Q99471,P21266,O60684,Q00169 17 +Histone kinase activity 0.4132726684888382 0.8273724947945084 0.4080259654476035 1.0 0.7079125339176827 11 Q9Y4B6,P24941,O14965,Q16512,Q99986,P06493 6 +Pseudouridine synthase activity 0.5370414824711633 0.80523922424008 0.42068164562493 1.0 0.7211524929256579 5 Q96PZ0,Q8WWH5 2 +Adenylate cyclase binding 0.6770894213910075 0.7885279856350029 0.4303879355765176 1.0 0.7276451150062346 3 P0DP25,Q02952 2 +Glutathione disulfide oxidoreductase activity 0.6767971946230169 0.7874618909101178 0.4310115286806275 1.0 0.7276451150062346 3 P00390,P35754 2 +Peptide hormone receptor binding 0.6765630851074269 0.7866080566799573 0.4315113415043956 1.0 0.7276451150062346 3 Q06124 1 +Hormone receptor binding 0.6765630851074269 0.7866080566799573 0.4315113415043956 1.0 0.7276451150062346 3 Q06124 1 +Oxidoreductase activity acting on ch or ch2 groups 0.6736780601811347 0.7823276719830238 0.4340220282678912 1.0 0.7287910334994855 2 P31350 1 +Catalytic activity acting on dna 0.2671399778119389 0.7788492413428423 0.4360685272256352 1.0 0.7297052041385186 90 Q16658,Q96FZ2,Q9UQ84,P49736,P40938,Q9UPY3,P40937,Q9H4L7,Q14527,Q8N3C0,P27695,P13010,O14646,P23396,P33991,P39748,P18074,Q07864,P15531,P52701,P46063,Q12873,Q86WJ1,Q9HCK8,Q96QE5,P18858,O14981,P56282,P35251,Q8IV08,Q13283,P38935,P13051,P25205,P13984,Q9Y620 36 +Demethylase activity 0.3787425807665224 0.7776264553227407 0.4367892601939642 1.0 0.7298285183174367 14 Q9UPP1,Q16850 2 +Lipopolysaccharide binding 0.460400444140935 0.7693804843534069 0.4416674705099335 1.0 0.7319311905817146 7 P09429,P28070 2 +Profilin binding 0.5565161040171172 0.767712558387267 0.4426579735340716 1.0 0.7319311905817146 4 Q8N8S7,P42858 2 +Tubulin binding 0.256807470568842 0.7649843293148484 0.4442808761073555 1.0 0.7330375248725797 112 Q15018,Q15691,Q9H6D7,P15311,Q14203,P16949,Q16512,Q9HC35,Q15813,Q86VS8,Q9H6U6,Q9P258,P78559,P23396,P42858,O43670,P41208,Q15814,O14737,Q9HB71,Q9UHD1,Q00535,P46821,Q15555,Q8IWC1,P61758,P43034,Q9P265,O75122,Q7Z460 30 +S adenosyl l methionine binding 0.6703682057276437 0.7640932099218922 0.4448116983925843 1.0 0.7330579738078254 3 Q99873,Q9HCE5 2 +Nf kappab binding 0.3651716970098402 0.7505398352301712 0.4529296413892121 1.0 0.7397060678863083 15 O95999,P49841,P42771,P60900,O43823 5 +Phosphatase binding 0.2709211869002649 0.7486948219578318 0.4540411653225997 1.0 0.740242511624373 54 Q8IV63,P17931,O43768,O60493,Q5H9R7,P42224,P15927,Q9P2B4,Q16539,Q9Y496,Q9H4A3,Q9NYB0,O95793,P78318,O43815,O00203,P62258,P46940,Q15257,P55199 20 +Insulin receptor binding 0.4846504097264362 0.7463544731306464 0.4554533133756751 1.0 0.740242511624373 6 Q13596,O60749 2 +Dna clamp loader activity 0.454790678148417 0.7430867758704949 0.4574291453845736 1.0 0.7404428557033019 7 P40938,P40937 2 +Rna 7 methylguanosine cap binding 0.4255736288908771 0.7397486180656345 0.4594525416861978 1.0 0.7408003425982237 8 Q96C86,Q6PKG0 2 +Epidermal growth factor receptor binding 0.4808069732187758 0.7294617701509457 0.4657192448163711 1.0 0.7445385090321678 6 Q13596 1 +Peptide n acetyltransferase activity 0.3783556772177734 0.7262336921283967 0.4676955206944471 1.0 0.7445385090321678 13 P41227,Q86UY6,Q9BXJ9,O14929,O95251,O75448 6 +Chaperone binding 0.2752964539588289 0.7217775940674039 0.4704312270749982 1.0 0.7465653816880442 44 Q9NQP4,O15212,O95433,O60884,Q15813,Q92995,Q16543,Q15814,P25685,O95817,Q8WXX5,O95429 12 +Insulin like growth factor receptor binding 0.5433924096297318 0.715580136755317 0.4742506422477797 1.0 0.7509411065379177 4 P46108,Q04917 2 +Mirna binding 0.3578633945119969 0.7073692562436992 0.4793370371285324 1.0 0.7571033364285619 15 P67809 1 +Phosphatidylinositol phosphate binding 0.2811780174671555 0.7067068869788916 0.4797486488260194 1.0 0.7571033364285619 38 Q96L92,Q9UMY4,Q7Z3T8,O60493,Q96AC1,Q9BPX3,P07737,P35080,O00560,Q9Y5X3,Q6IBS0,A1X283,Q13045,Q9BTX7,P46940 15 +Translation initiation factor binding 0.3438186959096878 0.7041390997034663 0.4813461525769922 1.0 0.7573649586640865 18 Q6PKG0,P06730,P62847,P20042,O75312,Q04637,P55010,Q13144,P55884,O00303,Q06787 11 +Tau protein kinase activity 0.4463539054082813 0.7038879579190039 0.4815025513182163 1.0 0.7573649586640865 7 P49841,O75116,Q13131,Q00535 4 +Death domain binding 0.6535674653751378 0.7038578777831934 0.481521285600434 1.0 0.7573649586640865 3 Q13546 1 +Cell cell adhesion mediator activity 0.344321647777061 0.6924236018356343 0.4886713482233613 1.0 0.7596303653274816 17 Q9UQB8,P04083,Q15417 3 +Mismatched dna binding 0.5087379776506487 0.6882140469419307 0.4913179994090841 1.0 0.7617583894346985 5 P54277,P52701 2 +Trna specific ribonuclease activity 0.5340082807914845 0.6788403298251692 0.497239037044183 1.0 0.7692516393659462 4 Q99575,P78346 2 +Dna binding bending 0.4683457725864148 0.6752724222526035 0.4995027016379805 1.0 0.7713932590417636 6 P09429,O15347 2 +Histone arginine n methyltransferase activity 0.6451610880042242 0.6742185311170391 0.5001723899042048 1.0 0.7713932590417636 3 Q86X55 1 +Glucose binding 0.4680692500214679 0.6740807380256411 0.500259984824114 1.0 0.7713932590417636 6 P13807 1 +Scaffold protein binding 0.3233010350232808 0.6666229425082575 0.5050130106913824 1.0 0.7761830403452333 23 Q9Y4P1,Q99497,Q02750,Q16543,P36507,P17480,Q9UQB8,P46108,P62258,P07900,Q8IWS0 11 +Dna binding transcription repressor activity 0.3825666358654379 0.6641158506200283 0.506616166000758 1.0 0.7763063842093934 11 P04150,P51858 2 +Carbohydrate kinase activity 0.4099640931006609 0.663064383226869 0.5072893203744551 1.0 0.7763063842093934 8 P51570,P08237,Q9UJ70,Q9Y223 4 +Collagen binding 0.4096503656651004 0.6615419028290521 0.5082648514260386 1.0 0.7769583782880201 8 Q92791 1 +Lactate dehydrogenase activity 0.6409582237803145 0.6586046987034349 0.5101496448293326 1.0 0.7770922731883024 2 P00338 1 +L lactate dehydrogenase activity 0.6409582237803145 0.6586046987034349 0.5101496448293326 1.0 0.7770922731883024 2 P00338 1 +Heparin binding 0.3645777014068588 0.6506815678325392 0.5152520640098228 1.0 0.7801850146579119 13 O14737,O43670,P51858 3 +Vitamin d receptor binding 0.4590916785535645 0.6356710247043985 0.5249908658741163 1.0 0.7902528303554363 6 O60244,O75448 2 +Structural constituent of synapse 0.4312993463286946 0.6351280868301111 0.5253448801514216 1.0 0.7902528303554363 7 Q16352,P12814,P07196 3 +Ribosome binding 0.2699283821775579 0.6280640614948861 0.5299619748167455 1.0 0.7955055545550722 40 P62495,Q99543,P42345,P63241,P41227,Q9NTK5,Q9BXJ9,Q9UBQ5,Q9NUL3,Q7Z739,Q92616,O76094,P38935,Q86UK7,O60678 15 +Four way junction dna binding 0.4563561543260246 0.6240805196520924 0.5325747065697151 1.0 0.7985796766591485 6 O15347 1 +Dna n glycosylase activity 0.4921461021300696 0.6216714394315744 0.5341579353280477 1.0 0.8001052124511223 5 P23396,P27695,P13051 3 +Atpase activator activity 0.3660587125673475 0.6171456480252319 0.5371386619617682 1.0 0.8016057072243431 12 O95433,Q99543,O60884,Q99615,P25685,P31689 6 +Phosphatidylinositol binding 0.2492504448329349 0.6138606042488929 0.5393074452136839 1.0 0.8016057072243431 64 Q15075,Q9UJY5,O60493,Q15036,Q96AC1,Q9H6U6,P07737,Q92783,Q9H490,P35080,Q9UNH7,Q13596,Q6IBS0,A1X283,Q9Y5X3,Q00169,Q9BPX3,O60749 18 +Immunoglobulin binding 0.6278118609407042 0.6107460619096509 0.5413677067388567 1.0 0.8016057072243431 2 P17931 1 +Myosin ii binding 0.6278118609407006 0.6107460619096385 0.5413677067388649 1.0 0.8016057072243431 2 O14745 1 +Frizzled binding 0.6278118609406991 0.6107460619096338 0.541367706738868 1.0 0.8016057072243431 2 O00560 1 +Sh2 domain binding 0.371493196584376 0.6072552539589382 0.5436815285964012 1.0 0.8024693960702624 11 P46108,A1X283,Q8NEM2 3 +Carboxypeptidase activity 0.3607111732208113 0.5896012176096426 0.5554580351960192 1.0 0.8135515919679598 12 P42785,Q9H3G5 2 +Atp dependent chromatin remodeler activity 0.4831823197321447 0.586496037562547 0.5575422235279381 1.0 0.8135515919679598 5 Q9H4L7 1 +Histone methyltransferase activity h3 k36 specific 0.507348159334136 0.5773892857305104 0.5636765103826797 1.0 0.8153603339698299 4 O96028 1 +Ribosomal large subunit binding 0.3796437444025301 0.5765899249013321 0.5642165068362492 1.0 0.8153603339698299 9 P98179 1 +Histone acetyltransferase binding 0.442990087342344 0.5682871630777685 0.5698399941066068 1.0 0.8164921669378803 6 O95905,P42224,Q9H6U6 3 +Ubiquitin like protein specific protease activity 0.2643612338200951 0.5649392182767898 0.5721151071524953 1.0 0.8164921669378803 38 Q01804,Q96K76,P51665,Q96FW1,Q92995,Q7L5N1,P40818,O94966,Q92905 9 +Ubiquitin like modifier activating enzyme activity 0.377027978159468 0.5639354581547046 0.5727980575372651 1.0 0.8164921669378803 9 Q9GZZ9,Q9UBE0 2 +Cell adhesion mediator activity 0.3183703810165344 0.5639107518026426 0.5728148724203517 1.0 0.8164921669378803 19 P04083 1 +Ligase activity forming phosphoric ester bonds 0.5027536383575641 0.560406401195738 0.5752022664142464 1.0 0.8177508710105873 4 O00442 1 +Dihydropyrimidinase activity 0.6104617182933951 0.5560845892079326 0.5781530296212103 1.0 0.8199682887506433 3 Q16555,Q14195 2 +Dna polymerase binding 0.3667801406430481 0.5482641510742947 0.5835105389456454 1.0 0.8249071392571655 10 P09429,Q9NVI1,P08238,Q9BXW9,P07900 5 +Wd40 repeat domain binding 0.4992583707152749 0.5475966132536252 0.5839689154147261 1.0 0.8249071392571655 4 Q96K76,P40227 2 +Cell adhesion molecule binding 0.2625657031178857 0.5414257986174456 0.5882141291375769 1.0 0.8288127633883303 232 Q16658,Q9Y6E2,Q15691,O75874,P13639,P20073,P25685,Q06124,P78344,Q14258,Q8WX93,P04083,Q9H2G2,Q9H3U1,Q9UQB8,P18206,Q9BPX3,P47914,Q99439,O60763,Q8WWM7,Q8NC51,P28072,O95067,Q96TA1,Q14247,Q15365,Q9NUQ8,Q9H4M9,Q99961,Q8TCG1,Q9UGI8,Q99497,P26196,Q5T6F2,P15311,P15880,O00560,P62826,Q12792,P61978,Q8WU90,P42356,Q9NZZ3,Q15056,P07737,P08238,P20810,P26641,P53990,P83731,Q13177,O95817,P62750,Q9NTK5,P55010,Q9UBC2,O95433,Q12955,Q9Y266,P09429,Q96AC1,O60664,Q13596,P14618,P46109,P29692,Q92616,P63104,O60749,P26038,O00299,P60228,P42224,Q15417,P31939,Q14677,P31946,Q6PKG0,Q9UHD8,Q9UNF0,Q9H223,Q15019,P08865,P00338,P40818,P35241,P62258,Q9Y5X3,P46940,P30041,P35613,Q96HC4,Q7L1Q6,Q6IBS0,Q9HC38,Q9UHB6,Q9Y5K6 98 +Peptide binding 0.2432008074964317 0.5410222729670182 0.5884922308641327 1.0 0.8288127633883303 74 Q9BYT8,Q9NQP4,P24390,O15212,P52294,Q6P179,O43813,Q9UHV9,Q15392,P28161,P21266,O60684 12 +Lys48 specific deubiquitinase activity 0.4341901443775275 0.5323889037666416 0.5944566688145374 1.0 0.8357966494093233 6 Q92995 1 +Nitric oxide synthase regulator activity 0.4945072454919419 0.5303424995502848 0.5958744852688567 1.0 0.8357966494093233 4 P08238,P0DP25 2 +Phosphoprotein binding 0.2684378063162332 0.5270151462070087 0.5981830704524869 1.0 0.8357966494093233 31 Q92541,P46109,Q06124,P07737,Q13526,P46108,P46934,P31946 8 +Protein phosphatase binding 0.2534368392290928 0.5267496452525834 0.5983674551922009 1.0 0.8357966494093233 44 Q9P2B4,Q16539,Q8IV63,P17931,O43815,Q15257,Q9Y496,O43768,O60493,Q5H9R7,P42224,O00203,P15927,P62258,O95793,P78318,P46940 17 +Hsp70 protein binding 0.3162219870634976 0.5261688903650384 0.5987708669389282 1.0 0.8357966494093233 17 O60884,Q99543,O75937,P25685,P23396 5 +Annealing activity 0.3589051643559873 0.5104178892059973 0.6097587266090181 1.0 0.8473135417192891 10 P23588,Q15056 2 +Protein carboxyl o methyltransferase activity 0.5988898626935479 0.5100480323734798 0.610017811506532 1.0 0.8473135417192891 2 Q9H993 1 +Armadillo repeat domain binding 0.4874096487619208 0.5049223079508814 0.6136134051267927 1.0 0.8514713982819283 4 O43815,Q9HCK8 2 +General transcription initiation factor activity 0.3621742731781976 0.4936253093005144 0.6215708230967008 1.0 0.8591409030877174 9 P35269,P17480,Q12962,P29083,P13984,Q9HBM6 6 +Supercoiled dna binding 0.4575640563895412 0.4895366861939558 0.6244617883530008 1.0 0.8607024197960776 5 P09429 1 +Stat family protein binding 0.5921706105755313 0.4876734910302517 0.6257811313917971 1.0 0.8609248660119785 2 Q8TDB6 1 +Molecular carrier activity 0.2562775436707367 0.4801098295616387 0.6311492991275967 1.0 0.8635902920364148 34 Q92973,Q9Y5L0,P52294,Q99497,P40855,Q9UIA9,P55060,O95817,Q9HAV4,Q9C0E2,P62826,O00505,O60684 13 +Map kinase kinase kinase activity 0.5858583120981273 0.4772399787084388 0.6331912458158486 1.0 0.8650554797909275 3 P10398 1 +D threo aldose 1 dehydrogenase activity 0.4790996784566081 0.4757327578998198 0.6342647802082824 1.0 0.8653200267071969 4 P15121,P48507,P14550 3 +Keratin filament binding 0.5847132257790255 0.4736851034294816 0.6357244776826065 1.0 0.8660061767275584 3 P08670 1 +Muscle alpha actinin binding 0.4775850753600719 0.4704822835313079 0.6380104888450226 1.0 0.8661877398704616 4 Q96HC4,Q8WX93 2 +Alpha actinin binding 0.4775850753600719 0.4704822835313079 0.6380104888450226 1.0 0.8661877398704616 4 Q96HC4,Q8WX93 2 +7s rna binding 0.4171643526438932 0.4650940879835356 0.6418640795338288 1.0 0.8676824172665717 6 Q9UHB9,O76094,P49458 3 +Protein kinase b binding 0.5814187874417714 0.4635182934390877 0.6429929054321988 1.0 0.867858685936418 3 Q13243 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.4153316506085692 0.4580361024692242 0.646926504031234 1.0 0.867858685936418 6 Q16555,Q14195,Q02127,Q9BPU6 4 +Peptide transmembrane transporter activity 0.473838059047076 0.4575887316981763 0.6472479406083367 1.0 0.867858685936418 4 Q03518,O15439,P33527 3 +Protein kinase c binding 0.3199556208839404 0.456358660173525 0.6481320879412005 1.0 0.867858685936418 14 Q96HC4,Q16512,P04792 3 +Mannosidase activity 0.5807770961145297 0.4507117681528188 0.6521972995817513 1.0 0.8724758577186342 2 Q16706 1 +Lipoprotein particle receptor binding 0.3316733135820986 0.4470098855490717 0.6548679222986789 1.0 0.874205196488726 12 O43813,Q15036 2 +Polyubiquitin modification dependent protein binding 0.3108442554129391 0.4463495453900504 0.6553447724738681 1.0 0.874205196488726 15 Q15018,P54727,P35573,P54725,Q04323 5 +Guanyl nucleotide exchange factor activity 0.2456611545573195 0.4444906988080542 0.6566878520489592 1.0 0.8751711807702435 42 P49770,Q5VZ89,Q14232,P29692,Q9NR50,Q96HP0,Q9Y2L1,Q13144,Q9Y4F1,Q15042,P80303 11 +Atp dependent protein binding 0.5748520005766707 0.4435276730006033 0.6573841075890141 1.0 0.875274131949968 3 Q9UBE0 1 +Gamma tubulin binding 0.3492388758782208 0.4348251886036194 0.663689320134778 1.0 0.8811799987517147 9 P07948,O00571,Q9BSJ2,Q92597,Q96SN8,Q96CW5,Q9H0H5,Q16512 8 +Aminopeptidase activity 0.3081771042853684 0.4326904952590986 0.6652396357986545 1.0 0.8824097983295474 15 Q6P179 1 +Protein homodimerization activity 0.2298866366779453 0.429778687903082 0.6673566372891648 1.0 0.8843882709717704 177 Q8TCG1,Q9GZZ9,Q99497,P34913,O75874,P51665,P51114,O75351,Q8N2A8,Q13043,Q93062,P51617,P55327,P60891,Q15075,P19474,Q9UNH7,Q13596,Q5HYI8,Q13137,P46976,O43598,P08238,P78356,P31350,P67936,P04792,Q04837,Q9HB71,Q9C005,Q13546,Q9HD42,O60749,Q15257,O75223,P49591,P28161,P21266,Q9UKK9,Q15102,P11908 41 +Transmembrane transporter binding 0.2491558051639197 0.4278537093193166 0.6687576308869729 1.0 0.8854150656125278 34 P42858,P0DP25,P62942,Q96PU5 4 +Phosphatidylinositol 4 5 bisphosphate binding 0.297050797845223 0.4208814668279608 0.6738416391036683 1.0 0.8904785772827916 17 P07737,P35080,Q6IBS0 3 +Protein disulfide reductase nad p activity 0.4036631897390203 0.4140293087237355 0.6788526425609944 1.0 0.8934380458449593 6 P00390,P35754,Q6DKJ4 3 +Atp dependent activity acting on dna 0.2327744200333844 0.3983353924509312 0.6903829749933426 1.0 0.9000623731294829 56 P49736,P40938,P40937,Q9H4L7,Q14527,Q8N3C0,P13010,O14646,P33991,P18074,P52701,P46063,Q12873,Q86WJ1,Q9HCK8,O14981,P25205,P38935,Q13283,P13984,Q9Y620 21 +Gtpase inhibitor activity 0.3992932292896965 0.3979840812087618 0.6906419199755933 1.0 0.9000623731294829 6 Q13098,O00410,O43924,P46940 4 +Translation elongation factor activity 0.3141524746109647 0.3958833952712641 0.692191051124198 1.0 0.900241890431887 13 P24534,P26641,P29692,P63241,Q9Y450,Q05639 6 +Oxygen binding 0.5578476883418589 0.3935594336251861 0.6939063362060971 1.0 0.900241890431887 3 O75306 1 +Mrna 5 utr binding 0.2836104089744086 0.3925061869095444 0.6946842408848943 1.0 0.9003515275996705 21 Q9Y6M1,P62081 2 +Damaged dna binding 0.2490317360100376 0.3906211736301542 0.6960772724158 1.0 0.9013308271025102 31 P09429,P18074,P52701,P27694,P12004,P35244,P27695,P54727,P15927,P13010,P54725,P13051,P28340,P23396,P39748 15 +Dna insertion or deletion binding 0.4524236322660798 0.386700464789255 0.6989779720226228 1.0 0.9026071711780718 4 P12004,P52701 2 +Nuclear import signal receptor activity 0.3118657296547972 0.385400753167006 0.6999405246485124 1.0 0.9030254578950698 13 Q9Y5L0,Q92973,P52294,O00505,O60684 5 +Single stranded rna binding 0.2344147558721089 0.3728839934990874 0.7092347856023622 1.0 0.9113174647672972 44 P23588,Q13325,P51114,Q15056,P38935,Q93062,P05455 7 +Peroxiredoxin activity 0.3910583031764105 0.3684377050491756 0.7125468871486582 1.0 0.912647026462572 6 P30041,Q99497 2 +Glutathione oxidoreductase activity 0.446150612163625 0.3669065846472381 0.7136886996531981 1.0 0.912647026462572 4 O76003,P35754 2 +Nucleobase containing compound kinase activity 0.2848301039000718 0.366686839092224 0.7138526246588435 1.0 0.912647026462572 18 P15531,P22392,Q9Y3D8,P04183 4 +Kinase binding 0.2372447250383687 0.3601222171815891 0.7187557389741479 1.0 0.9146813264189432 202 Q15691,Q99497,P26038,P98170,P30086,P42771,Q06124,P15311,Q13043,Q14203,Q13526,P46108,P51617,Q16512,P50851,Q16539,P19474,Q96JJ3,Q13243,Q9H4A3,Q16543,Q96AC1,O60271,Q9P258,Q9Y4R8,P17612,P23396,Q05639,P42858,Q9UNI6,Q86Y37,Q14152,P08238,P46109,P49841,P39019,Q13177,P04792,Q92616,P04150,Q9UHD1,P63104,Q99873,Q99986,Q00535,P13807,P62081,Q15555,O95999,P18669,Q9UER7,O95747,Q96SZ6,Q9NUL3,Q9NQT8,P62753,Q96HC4,P51452,P54725,Q6IBS0,O14965,P0DP25,P07900,Q9UNN5 64 +Nucleoside kinase activity 0.4432516119574016 0.3579181056614015 0.7204046007579592 1.0 0.9146813264189432 4 P55263,P04183 2 +Peptide lysine n acetyltransferase activity 0.3245834653431864 0.3565476077761823 0.7214305056204262 1.0 0.9148903452441998 10 Q86UY6,O95251,O75448,O14929 4 +Glucosyltransferase activity 0.3406542968717894 0.3533101582595193 0.7238559308059418 1.0 0.9164644538778912 8 P46976 1 +Oxidoreductase activity acting on peroxide as acceptor 0.3102567851710957 0.3512985237070091 0.7253644023672372 1.0 0.9164644538778912 12 P30041,Q99497,P28161 3 +Fructose 6 phosphate binding 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.9164644538778912 3 P08237 1 +Phosphofructokinase activity 0.5405857310569657 0.3456952406007333 0.729571761449691 1.0 0.9164644538778912 3 P08237 1 +Hydrolase activity acting on ester bonds 0.2269543089784834 0.3394060678224704 0.7343038481382602 1.0 0.9190224070445788 184 P34913,P30153,Q99504,P15586,Q96C86,Q9UQ84,Q8N2A8,Q9BQ61,A6NDG6,Q9NPH0,O15355,Q969T7,Q06124,Q9UPY3,P35790,Q9H0R4,Q96F86,Q9Y3Z3,Q9BQG2,Q14738,Q9BRF8,P23396,Q9Y6Y8,P39748,Q9UNI6,Q07864,P15531,Q9H2U2,Q9BTV6,Q9HB07,Q01968,Q8NCE2,Q15631,Q99598,P30041,O60942,Q13614,Q8IV08,Q9Y2L1,P51452,Q13283,Q5VWZ2,Q15102,Q9NQ88 44 +Rna polymerase ii general transcription initiation factor activity 0.3353538951829698 0.3325221647324282 0.7394950059254872 1.0 0.9229002103959744 8 P35269,Q12962,P29083,P13984,Q9HBM6 5 +Nad retinol dehydrogenase activity 0.5384165936313312 0.3254611692868451 0.7448320666528556 1.0 0.924791963670794 2 Q8TC12 1 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.5323298915011695 0.3238976511048243 0.7460155223593736 1.0 0.9253210075580302 3 Q96SZ5 1 +Signaling receptor inhibitor activity 0.5357873210634073 0.3183831380980842 0.7501943271894631 1.0 0.9296886754127088 2 Q86XI2 1 +Co smad binding 0.5292226767971784 0.3158852559505126 0.7520896034198803 1.0 0.9304065610111204 3 P26367,Q93008 2 +Signaling receptor binding 0.2279310081157414 0.3128277881282205 0.7544115023359617 1.0 0.9324631680970716 190 P54577,P51858,Q99497,P62942,P17931,Q9H2J4,O43768,Q06124,Q9UMX5,O43776,Q13043,Q96J02,P46108,Q9Y3F4,P55145,P30046,Q8WUH2,P09429,Q96JJ3,O43813,P04083,P27695,Q9BY49,Q15036,Q96AC1,P31689,Q9UNH7,P07437,P14174,Q13596,Q13740,P30626,P06744,Q14152,P08238,P62195,P53621,P46109,Q13107,O00170,Q9NUQ9,P46934,P43490,Q13546,Q9Y5X3,Q00535,Q15257,P28161,Q04917,P51452,O60749,P0DP25,O60879 53 +Antioxidant activity 0.270561282883808 0.305370246464217 0.7600841800967397 1.0 0.9364471087874516 19 P30041,P00390,Q99497,P30044,Q6DKJ4,P28161 6 +Ribonuclease p activity 0.5212813093053452 0.2958958544539922 0.7673096170551001 1.0 0.9438583266958914 3 Q99575 1 +Receptor tyrosine kinase binding 0.2716251247633904 0.2952372325449012 0.7678126614747218 1.0 0.9438583266958914 17 Q14152,P46109,Q06124,P51452,Q13043,P46108 6 +Camp dependent protein kinase regulator activity 0.5204010900167364 0.2937241371148715 0.7689687087090555 1.0 0.9438583266958914 3 P54619 1 +Fructose binding 0.5193639183048562 0.291176560623775 0.7709162881874336 1.0 0.944806639391188 3 P08237 1 +Monooxygenase activity 0.3196705320641889 0.2741698116530109 0.7839541263488867 1.0 0.9543402178073982 8 Q16850 1 +Dystroglycan binding 0.3913856690674813 0.2720754728020555 0.7855639882645937 1.0 0.9543402178073982 5 O75122 1 +Omega peptidase activity 0.2228363783789129 0.2545346698283057 0.7990825231922891 1.0 0.9599852912437524 32 Q01804,Q96K76,Q96FW1,Q92995,P40818,O94966 6 +Glycosaminoglycan binding 0.2583805307561865 0.2500712457991719 0.8025322521668827 1.0 0.9622636367096238 19 O14737,O43670,P15586,P51858 4 +Antigen binding 0.3296595288374109 0.2379171578711922 0.811945347512292 1.0 0.9649031747623578 7 Q15392 1 +Peptidase activator activity involved in apoptotic process 0.4962958863277551 0.2377858083826295 0.8120472262851526 1.0 0.9649031747623578 3 Q9BXK5 1 +Ubiquitin like protein ligase binding 0.2052524804119532 0.2354761670661472 0.8138391747641576 1.0 0.965549377555886 124 Q93034,Q92995,P07900,P15927,Q96J02,P46108,Q99460,Q15370,O95429,Q14527,P78371,P31689,P13010,P07437,P17612,Q86Y37,P25788,P06744,P08238,Q96FW1,P49841,Q9HB71,Q92783,P68036,P63104,Q13546,Q8TDB6,P11233,P30041,Q9UQ80,O94888,P12277,Q9UER7,O95999,O94966,O14965,O75306,Q8N0X7,Q04323,Q9UNN5 40 +Ubiquitin like protein conjugating enzyme binding 0.2867406925545246 0.2353246561094811 0.813956759580351 1.0 0.965549377555886 11 P23396,Q9UBT2,Q96GG9 3 +General transcription initiation factor binding 0.2506494134718778 0.2244958069201093 0.8223715292540952 1.0 0.970782167645291 20 O75155,O14981,P62195,O95999,P42345,O60869,Q86VP6 7 +Spectrin binding 0.3434203376514442 0.2179446486652923 0.8274722386069411 1.0 0.9717854132688654 6 Q12955 1 +Enzyme activator activity 0.2057895349966179 0.2173036487168095 0.8279717137696521 1.0 0.9717854132688654 121 Q9P2J5,Q99497,Q15750,O75569,O94766,P05386,Q9UBE0,P12004,P36507,Q96FS4,Q9NVG8,Q15334,Q4KMP7,Q13043,Q0IIM8,Q9HC52,P52565,Q02750,P50395,Q9H4A3,P61803,Q9H6Z4,Q9H6U6,Q14738,Q68EM7,Q9H3U1,Q5JRX3,Q9H8V3,P13010,A1X283,Q9BTW9,Q06323,Q9Y263,Q15437,P11274,Q13177,O14737,P60983,P68036,P61289,Q96QE5,O00429,O60343,Q15042,Q01968,Q9UL46,Q8TDB6,P46940,Q15257,P35251,O95999,Q69YN2,P35269,Q9UER7,Q8TC07,P21359,Q8N6T3,Q15436,Q9NPI6,Q66K14,P0DP25 61 +4 iron 4 sulfur cluster binding 0.2399650823869607 0.2044847649397829 0.8379746962909973 1.0 0.9717854132688654 23 O75306,Q06203,Q9H9T3 3 +Microtubule binding 0.2115471450390742 0.2033726142778884 0.8388438031588645 1.0 0.9717854132688654 84 Q15018,Q15691,Q9H6D7,Q6NUK4,P15311,Q14203,Q9HC35,Q9Y496,Q86VS8,Q9P258,P78559,P23396,Q16555,O43670,P41208,P36405,Q9UHD1,Q00535,P46821,Q15555,Q8IWC1,Q9NQT8,P43034,O75122,Q7Z460 25 +Alditol nadpplus 1 oxidoreductase activity 0.478959672706001 0.2019376951712583 0.8399654325988475 1.0 0.9717854132688654 3 P15121,P14550 2 +Transcription coactivator binding 0.3365292704770699 0.1994259654241361 0.8419295509230251 1.0 0.9717854132688654 6 P42224,Q00059 2 +N acyltransferase activity 0.2402240732978202 0.1972363607919025 0.8436425776550776 1.0 0.9717854132688654 22 P41227,Q86UY6,Q9BXJ9,O95251,Q96G23,Q9H9T3 6 +Nad dependent protein deacetylase activity 0.3800058462437896 0.1902840280549132 0.8490865687629687 1.0 0.9717854132688654 4 O15379,Q92769,Q96EB6 3 +Tripeptide transmembrane transporter activity 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.9717854132688654 2 O15439 1 +Atpase coupled lipid transmembrane transporter activity 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.9717854132688654 2 O15439 1 +Abc type glutathione s conjugate transporter activity 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.9717854132688654 2 O15439 1 +Glutathione transmembrane transporter activity 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.9717854132688654 2 O15439 1 +Oligopeptide transmembrane transporter activity 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.9717854132688654 2 O15439 1 +Histone serine kinase activity 0.357138062790549 0.1841312943209914 0.8539104568682259 1.0 0.9755014890218032 5 O14965,Q99986 2 +Unfolded protein binding 0.2028149066784078 0.1824894567732128 0.8551986277131705 1.0 0.9758843751534736 61 Q9NQP4,P25685,Q9Y266,Q99733,Q9UHV9,Q16543,P78371,Q99471,P31689,P08238,O15212,Q99614,O00170,Q8WVJ2,Q7Z4Q2,Q8IVD9,O60884,P61758,O75190 19 +Protein tyrosine kinase inhibitor activity 0.4649327878433529 0.1757121767911967 0.8605200684533365 1.0 0.9777613175824016 3 P63244,Q86XI2 2 +Camp dependent protein kinase activity 0.3519853497749046 0.1725888354180834 0.8629746282481168 1.0 0.9777613175824016 5 P17612,Q13131 2 +Cyclic nucleotide dependent protein kinase activity 0.3519853497749046 0.1725888354180834 0.8629746282481168 1.0 0.9777613175824016 5 P17612,Q13131 2 +Ephrin receptor binding 0.2860604177906962 0.1670707455662947 0.86731438411829 1.0 0.97808390054939 8 P46108 1 +Carbon nitrogen lyase activity 0.3483408712937846 0.1647010101834399 0.8691793218294184 1.0 0.9788908513566592 5 Q8WUX2 1 +K48 linked polyubiquitin modification dependent protein binding 0.3668517977199654 0.1629821778864615 0.8705324670243488 1.0 0.9792624569390844 4 Q92890,Q8TAT6,Q04323 3 +Aspartic type endopeptidase inhibitor activity 0.4642126789366235 0.1614424699556166 0.8717449191697042 1.0 0.9795330103004471 2 Q13464 1 +Dna secondary structure binding 0.2683956586056042 0.1578654239279423 0.8745628440733006 1.0 0.9806755444247796 10 O15347 1 +Protein tyrosine kinase binding 0.2292433118710301 0.1501435136778092 0.8806513901194131 1.0 0.9820513135874211 21 Q14152,P46109,Q06124,P51452,Q13043,P46108 6 +G quadruplex rna binding 0.4545720128542369 0.1458017833243537 0.8840778680607764 1.0 0.9831836574277896 2 Q06787 1 +Aminoacyl trna editing activity 0.2629575402635405 0.1429424753524738 0.8863356125145501 1.0 0.9831836574277896 10 Q9P2J5,Q5ST30,Q9BTE6,P26640,P41252,P49588,Q5JTZ9,Q15031,Q9NSE4 9 +Nucleoside monophosphate kinase activity 0.2608499293592513 0.1373797970563708 0.8907305992434242 1.0 0.9831836574277896 10 Q9Y3D8 1 +Catalytic activity acting on a trna 0.1965621867298009 0.137018745461239 0.8910159781211495 1.0 0.9831836574277896 58 P54577,P49589,Q9NXH9,Q13395,Q99575,Q9HA77,Q9Y606,Q9NX74,Q9UBP6,P26639,P26640,P78346,Q9Y285,Q9BTE6,Q9BQ52,P49591,Q7Z4G4,Q9NSD9,A2RTX5,O43776 20 +Extracellular matrix binding 0.3519438760596315 0.1353951043925131 0.8922994946213414 1.0 0.9831836574277896 4 P08865,P17931,O94813 3 +Laminin binding 0.3519438760596315 0.1353951043925131 0.8922994946213414 1.0 0.9831836574277896 4 P08865,P17931,O94813 3 +Amp activated protein kinase activity 0.3516515638702129 0.1348899137439565 0.892698914331012 1.0 0.9831836574277896 4 P17612,Q13131,P54646 3 +Isomerase activity 0.1978600013183808 0.1251886176926385 0.9003742281186256 1.0 0.9831836574277896 77 P62942,Q08426,Q00688,Q13526,P30046,Q96AY3,Q96G03,Q13572,Q9BV20,Q15125,P14174,Q5T1M5,Q13630,P06744,P34949,P36871,Q96JJ7,O00170,Q13907,Q96BP3,Q15257,P18669,Q8WWH5,Q9Y223 24 +Mrna 3 utr binding 0.1941130378265748 0.1245570042763289 0.9008742688438072 1.0 0.9831836574277896 48 Q14011,Q9Y6M1,P16989,P62081 4 +Calcium dependent cysteine type endopeptidase activity 0.4310344827586152 0.1227149123274529 0.9023328547917402 1.0 0.9831836574277896 3 P07384,P17655 2 +K63 linked polyubiquitin modification dependent protein binding 0.3443437591347558 0.1227051169616371 0.9023406117413966 1.0 0.9831836574277896 4 Q8NCN4,Q96RL1,Q8TAT6 3 +Nuclear receptor coactivator activity 0.223598000181554 0.1226864238366522 0.9023554148519276 1.0 0.9831836574277896 19 O60244,Q16512,Q86X55 3 +Endopeptidase regulator activity 0.2092193027155593 0.1224704581392369 0.9025264408354108 1.0 0.9831836574277896 27 P04080,P20810,P98170,P30086,Q9C0C9,P61201,Q9UL46,P30740 8 +Eukaryotic initiation factor 4e binding 0.3396667641040629 0.1153538367589606 0.9081646675574552 1.0 0.9838182889357904 4 Q04637,Q6PKG0,O00571 3 +Cargo adaptor activity 0.2579039812646363 0.1144246905738682 0.9089011422874028 1.0 0.9838182889357904 9 Q5SW96,Q96CW1,P53680,P63010,O43747,O94973,Q9BXS5,O95782 8 +Phosphatidylinositol 4 phosphate binding 0.2817548062121895 0.1139207245223437 0.9093006367247424 1.0 0.9838182889357904 7 O60493,Q9H4A6,Q9Y5X3,Q9NS86 4 +Neurotrophin trk receptor binding 0.4297399941571764 0.111450114939108 0.9112594215803826 1.0 0.9838182889357904 2 P62993 1 +Neurotrophin receptor binding 0.4297399941571764 0.111450114939108 0.9112594215803826 1.0 0.9838182889357904 2 P62993 1 +Transcription coregulator binding 0.2075825152647082 0.1100638139642258 0.9123587660291236 1.0 0.984039126746896 26 Q9UQB8,P51858 2 +Nadplus adp ribosyltransferase activity 0.3349897690733732 0.1083484384717956 0.9137193003966664 1.0 0.984369674879318 4 Q7Z2W4,Q9ULX3,Q96EB6 3 +Tap binding 0.3346974568839539 0.1079220130142849 0.9140575552450813 1.0 0.984369674879318 4 P04439,Q03519,Q03518 3 +Kinetochore binding 0.41815044871842 0.1063605793665096 0.9152962687220882 1.0 0.9849535190053522 3 P33981 1 +Protein tyrosine kinase activity 0.2182452541801521 0.1012429201963326 0.9193576263441928 1.0 0.9864622728303214 17 P41240,Q02750,P36507,P11274,P33981,Q96KB5,P19525 7 +G rich strand telomeric dna binding 0.2866989905652797 0.0929582582840952 0.9259367226418392 1.0 0.9864622728303214 6 Q9NYB0 1 +Ligase activity forming carbon oxygen bonds 0.1879543879965591 0.0926822588806595 0.9261559916992206 1.0 0.9864622728303214 34 Q9HA77,P54577,P49589,Q9Y285,P26639,Q9BTE6,P26640,P49591,Q9NSD9,A2RTX5,O43776 11 +Ribonucleoprotein complex binding 0.1982459443973805 0.0925742830925124 0.926241775112274 1.0 0.9864622728303214 93 P15531,P23588,P16989,Q99543,Q9NTK5,P41227,Q9UBQ5,Q15056,O60678,Q7Z739,P38935,Q9HAV4,P13051,Q96J02,O76094,P98179 16 +Histone methyltransferase binding 0.2844958243465756 0.0893802952679926 0.9287796828849172 1.0 0.9864622728303214 6 P83916 1 +Oxidized dna binding 0.2839542312466572 0.0885151522499372 0.929467241854425 1.0 0.9864622728303214 6 P23396 1 +Sequence specific single stranded dna binding 0.2455260336033156 0.0869909200529436 0.9306787294950518 1.0 0.9864622728303214 9 Q15365,Q9NYB0 2 +Beta tubulin binding 0.2114089787613522 0.0842014012721298 0.9328963040927968 1.0 0.9866000917014456 17 Q9HC35,O14737,P42858 3 +Carbon nitrogen ligase activity with glutamine as amido n donor 0.2503101148357552 0.0833514629364776 0.9335720811149464 1.0 0.9866000917014456 8 P08243,P49915 2 +Ligase activity forming carbon nitrogen bonds 0.200878835745164 0.0786758165224342 0.9372904814602014 1.0 0.98928115549719 23 P11586,P49915,P22102,P50747,P48637,O75879,P30520,Q05932,P08243,Q9NRF8,P17812 11 +Protein phosphatase 1 binding 0.3086816720257176 0.0751904355618853 0.9400631941291028 1.0 0.9902476706750768 4 Q9UQ13,P62136,O95793 3 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.2747059672784222 0.0746097804250774 0.9405251921616888 1.0 0.9902476706750768 6 Q9UHG3 1 +Cyclohydrolase activity 0.3839860227897223 0.0724177586380261 0.9422694525498144 1.0 0.991345986536784 3 P11586 1 +Histone deacetylase activity h3 k14 specific 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9915254238899988 3 O15379,Q92769 2 +Transcription factor binding 0.1916036323172486 0.0684222702092519 0.9454494943074516 1.0 0.9915254238899988 164 O75155,P62191,Q99497,P42345,O60869,Q9UNN5,P42771,Q13043,Q9H1E3,O43251,O43823,Q15370,Q16512,P09429,Q16539,O60244,Q96T76,Q12800,P27695,Q9H6U6,P31689,Q9NUQ3,P60900,P13693,Q9UQB8,P23396,P30626,O75448,Q96AQ6,P62195,O43815,P46109,Q86TU7,P49841,P04792,O00170,O75832,Q02790,P63104,Q00059,Q8TDB6,O14981,O94888,O95999,Q9UER7,Q9Y4B6,Q04917,Q86VP6,P38935,P51858 50 +Peroxisome proliferator activated receptor binding 0.3818288051416929 0.0671968741909871 0.9464249735362766 1.0 0.9915254238899988 2 Q15648 1 +Hydroxymethyl formyl and related transferase activity 0.2907687853973412 0.0582972823447719 0.9535118322101904 1.0 0.9939032697093656 4 P22102,P31939 2 +Molybdopterin cofactor binding 0.3543994103910408 0.0527961616364387 0.9578943198076166 1.0 0.9939032697093656 3 Q969Z3 1 +Single stranded dna helicase activity 0.2017836025695404 0.0513148644840418 0.9590746235642104 1.0 0.9939032697093656 13 P40938,P25205,P33991,P49736 4 +Tumor necrosis factor receptor superfamily binding 0.2797154047243121 0.0499366095812391 0.96017290345641 1.0 0.9939032697093656 4 Q13546 1 +Histone binding 0.1907185057646058 0.0490657714405 0.960866880970794 1.0 0.9939032697093656 92 O95373,Q01105,P55209,Q08945,P39687,Q7Z4V5,Q9UPP1,Q99543,Q8WXX5,Q86X55,Q99733,P83916,P49321,O14646,Q16512,Q92688 16 +Ubiquitin specific protease binding 0.2180878181722837 0.0405968747316589 0.9676172757073068 1.0 0.9972200637704968 9 Q99497,P54725 2 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.2142857142857135 0.0356514586960118 0.9715602762710518 1.0 0.998571661126781 9 O15294,Q7Z3T8,Q96AC1,Q13576,Q92538,O43795,Q9H0H5,P46940 8 +Thioesterase binding 0.3007013442431362 0.034281441019664 0.972652724091384 1.0 0.9987879098512832 3 P62330,P60953 2 +Adp binding 0.1734019034792379 0.024415083972186 0.9805215166425024 1.0 1.0 20 Q9UHD1,P53041,P11908,P48163 4 +Poly a binding 0.1529894490035108 0.0114883605627978 0.9908338161076522 1.0 1.0 13 Q13310,Q9UNP9,P38919,O00571,Q00839,Q07666,Q71RC2,O14979,P31483,Q92499,Q93062,P11940 12 +Transcription corepressor binding 0.1418882973018475 0.0044349586855376 0.9964614265369648 1.0 1.0 14 P42224,Q15370,Q13363,P51858 4 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8c22aea15dab6b5c3f7d1bf2cc75abc57a7a368b --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 cyclic amp phosphodiesterase activity", "3 5 cyclic gmp phosphodiesterase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylesterase activity", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenosine receptor binding", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Benzodiazepine receptor binding", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Delta catenin binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hmg box domain binding", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n acetyltransferase activity acting on acetyl phosphate as donor", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Short chain carboxylesterase activity", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATR", "ATRX", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C1orf52", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "COASY", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT3", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFRKB", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYNCRIP", "SYNE2", "TAB1", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM201", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC28", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UIMC1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", 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40 2.4198985732688336 0.0155248366703364 7.924757281553398 36.20388349514563 0.3258157858828113 0.6059539058091996 3.6279214795080814 4.218795722199633 0.7682389896955812 0.3040770756760007 1.0 0.0171186596746025 0.0253675472895287 0.0635238976701175 0.203051251134211 +Bone pain 1 24 2.4196996935713653 0.0155333292673029 4.975728155339806 22.203883495145632 0.6350188771758896 0.4127751797545932 2.519707411717398 2.310210444333206 1.0375367125895096 0.3016728005813124 1.0 0.0256777347862131 0.0919415891551245 0.3708274474010383 0.7368510761860215 +Exostoses 1 5 2.4073057859445046 0.0160707074522736 1.8737864077669903 4.565533980582524 0.1227309696596917 0.3298370080715785 1.065155184012566 0.8232521681359034 1.4140930420981814 0.2989667883126048 1.0 0.0019049706229129 0.0077184558590264 0.0442367692127036 0.1462762019757018 +Hamartoma 1 23 2.384827465141966 0.017087133039068 5.114077669902913 19.118932038834952 0.0706830685782178 0.5277541380015572 3.0472167587078394 2.3364837129781897 1.0005550989773928 0.3098760828272325 1.0 0.0343104139968933 0.1194965359594502 0.1912240791272418 0.3563930320815741 +Malignant neoplasm of the central nervous system 5 29 2.3795267929980057 0.0173348827717279 6.453883495145631 23.82766990291262 -0.1035875416121286 0.5489059085312997 4.178110952578651 3.916843315852553 0.9853841716312314 0.3143838966418644 1.0 0.0473022522201117 0.1588529428511447 0.1055886940117485 0.0676022626142099 +Adenocarcinoma of the colon 7 20 2.360539680159365 0.0182483659711345 9.50485436893204 20.58009708737864 -0.5385965908043259 0.4099332106587272 4.098007534825994 1.3513359051095024 1.3067136508964234 0.352270731481182 1.0 1.0 1.0 0.1476943407876319 0.0103633783340074 +Limb undergrowth 5 60 2.357290104686242 0.0184088590090194 10.648058252427184 51.10436893203884 0.3980398713744312 0.5752346762319336 4.664982243954684 7.303495661229484 0.9215304205365352 0.3350258300048305 1.0 0.0539010452822664 0.0979989328881401 0.2824835291536199 0.666301519189102 +Rhizomelia 2 12 2.348922577997421 0.0188278212417865 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 1.0 0.1955113655682517 0.0720571885403784 0.100752004546059 0.389057813625451 +Platyspondyly 2 36 2.3123082941367983 0.0207606999439311 8.28640776699029 33.730582524271846 0.6662607465302498 0.4948187493576657 3.3732974430890796 4.074278380383408 0.9978722835718216 0.3450714604006198 1.0 0.00691212443146 0.0455644056460713 0.3284623958158804 0.3786561321310261 +Reticulocytopenia 6 19 2.2927417324431474 0.021862878382038 9.080097087378642 20.3495145631068 -0.5425157493239673 0.4273831624263773 4.101964008671714 1.5372951777001542 1.2418683534424684 0.3493223082114023 1.0 1.0 1.0 0.1476943407876319 0.0448872219881859 +Breast carcinoma 5 25 2.2798774816258 0.0226149559551418 5.269417475728155 21.303398058252423 0.0458449363367184 0.5512715013731206 3.6487445174839737 3.8323720894298465 0.9809579775350368 0.3254016536425757 1.0 0.0333019544595367 0.1163398228410075 0.0607417341965242 0.0750518175373725 +Abnormal upper motor neuron morphology 0 10 2.2675919766157784 0.0233540871634603 2.104368932038835 10.152912621359222 0.6668580581129538 0.4264480473015415 1.810508789672501 1.2708136152843803 0.93546763978058 0.305632736845798 1.0 0.0814971443263516 0.1596960736798767 0.3582816735878424 0.5927878722461318 +Erythroid hypoplasia 5 18 2.2635764677990338 0.023600176551846 9.390776699029129 19.1626213592233 -0.5527639828673522 0.3938582487298333 3.9957759709887206 1.0928989339971622 1.3343610146308624 0.3526294909242743 1.0 1.0 1.0 0.1147066696002357 0.0271057364081029 +Abnormal astrocyte morphology 1 18 2.2571412699772595 0.0239992488068634 3.54126213592233 16.20873786407767 0.4731534517279612 0.4675130828680874 2.35465792441142 2.5609315203013745 1.0847965639398074 0.3356447738091184 1.0 0.0173338143393145 0.0640285846884502 0.2813288077075832 0.1550661083475891 +Ovarian neoplasm 4 22 2.2414138988466616 0.0249992770420317 5.800970873786408 20.75485436893204 -0.0222415819970231 0.5296820866885116 3.7943748642961137 3.1322935435347152 1.0136090000570463 0.3142589571986427 1.0 0.0323055044295255 0.1132051672598368 0.1789420187780838 0.0704094801772502 +Abnormality of the thenar eminence 5 17 2.2288783991064864 0.0258219967207229 8.70388349514563 18.186893203883496 -0.5329823744436845 0.3958429743656864 3.804657909940043 1.1000984326005212 1.324691754247351 0.3505441151203373 1.0 1.0 1.0 0.1392702662277763 0.0399552443236748 +Multiple enchondromatosis 1 5 2.2249641926521755 0.0260836420391066 2.3907766990291264 5.83252427184466 -0.1493414935196237 0.3058932703062575 1.4381124288120406 0.3734000651234257 1.4514389248320605 0.2926213640255996 1.0 0.0007650215967213 0.0031504918831051 0.0189506401306209 0.0677640175569944 +Sclerocornea 1 9 2.203158813198711 0.0275835571047307 3.1237864077669903 9.691747572815531 0.6327344825269637 0.4627390478210677 1.6813417067808916 1.93451779053892 0.8687114450254205 0.3021244352075571 1.0 0.1524760813950871 0.0443091130960601 0.2089591760219589 0.5133655979735248 +Gonadal neoplasm 4 29 2.143424542073557 0.0320790241738722 6.218446601941747 25.74271844660194 0.0706966967021421 0.6037062367826098 3.687534698150144 3.9322935312452594 0.896989985626744 0.3132109357694278 1.0 0.058039929090825 0.1897338295109766 0.3284623958158804 0.108533579096118 +Partial duplication of the phalanx of hand 6 19 2.1379365621684343 0.0325218922981067 8.631067961165048 20.58252427184466 -0.4012090744680646 0.4761024817004221 4.063190891243266 1.6281758918641962 1.159132332873358 0.3522167351772669 1.0 1.0 1.0 0.1911341037783432 0.0743636419116672 +Subcutaneous nodule 1 19 2.120353417474633 0.0339762519804514 5.174757281553398 17.716019417475728 0.7715929851765809 0.3892857335439222 2.3624373807533945 1.5246949972287631 1.0645096840549642 0.3076166958299045 1.0 0.0265864003984115 0.0949012099695084 0.1435696883620607 0.2675058784158126 +Hypothermia 1 11 2.119655324365772 0.0340351231764994 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 1.0 0.0051552423978184 0.0202898922491691 0.1067922158236129 0.3089323218960526 +Neoplasm of the genitourinary tract 15 74 2.1118438075791577 0.0346998484334681 18.987864077669904 68.5995145631068 -0.3030475290592401 0.5946122252326792 8.956331399455076 8.147743731837105 0.8540328943632708 0.3189032933670377 1.0 0.2180602949831368 0.2652671769721049 0.0841389456843221 0.019109570139867 +Adenocarcinoma of the intestines 8 23 2.1012895618270773 0.0356155554867756 9.817961165048544 23.133495145631063 -0.4723450275482979 0.4508190526442003 4.3925541277805715 1.8139546502813697 1.2296228934527935 0.3539411393556459 1.0 1.0 1.0 0.2179356607727124 0.0289613396123399 +Dicarboxylic aciduria 1 24 2.100593682730439 0.0356766490675477 6.055825242718447 23.638349514563107 0.3728164181913581 0.4495949589967114 3.6721584415633983 2.075699716898563 1.1546872481244734 0.3062788418550133 1.0 0.0158345246348345 0.0588586045542952 0.0771340965144245 0.3217125501336962 +Ventricular tachycardia 2 12 2.0882786541048146 0.0367727058239113 3.029126213592233 13.262135922330096 0.686137979317516 0.4029577645071625 1.751317455154925 1.7554971361746374 0.9579673572740748 0.2804177345045502 1.0 0.1197698958477507 0.2297987482657219 0.0270423729706739 0.0399552443236748 +Increased susceptibility to fractures 3 54 2.0845461571986834 0.0371105162711062 11.298543689320388 52.63834951456311 0.6062165983596748 0.5457625999772061 4.708049068828723 5.888757199406996 0.818710666746425 0.3467528628559314 1.0 0.004816744831825 0.0519232868725963 0.476649182034557 0.5706229404247211 +Neoplasm of the nervous system 11 58 2.0772997875876285 0.037773898676443 11.822815533980584 48.23300970873787 -0.1802500971143466 0.6254658302050053 6.245010733622454 6.229360302358884 0.7922345469946627 0.3074763076117138 1.0 0.1652115770845257 0.4407901339858018 0.0840205851235919 0.0388401839530869 +Osteolysis 1 30 2.0438271151167893 0.0409706294565146 5.286407766990291 27.73543689320388 0.5057473150905948 0.5186942536500823 2.7835351045722914 3.2828484188526224 0.8911453392732208 0.3083503296551068 1.0 0.0333019544595367 0.1163398228410075 0.4391828158382775 0.3451855796466592 +Pure red cell aplasia 6 19 2.0144884988218723 0.0439582711794761 9.682038834951456 20.15776699029126 -0.6022526598961478 0.4049157755999357 4.214902792697585 1.1002483674054329 1.2808463277930804 0.3519742047774726 1.0 1.0 1.0 0.1067922158236129 0.0234644839392777 +Premature ventricular contraction 0 7 2.0085721662738028 0.0445825255839051 1.480582524271845 6.645631067961165 0.3887689762072841 0.3497972460308874 1.4234893714961696 0.5447501786076202 1.2366408357670695 0.2803988641190083 1.0 0.0325017468768143 0.0653907127050202 0.1583736196074974 0.042147958906207 +Persistence of hemoglobin f 5 19 1.997706443168935 0.0457484952766118 9.99514563106796 20.521844660194176 -0.5746459483062162 0.4024883106854605 4.363904874706898 1.4011120739722107 1.3072723321569808 0.3541603521194014 1.0 1.0 1.0 0.1147066696002357 0.0271057364081029 +Abnormal urine ph 2 46 1.996646974443824 0.0458635461310099 10.177184466019416 42.75485436893204 -0.2614532644322701 0.3885797701125258 5.53805579383966 4.205936711312748 1.3405853425418588 0.3191717661997511 1.0 0.0060275441501108 0.0402942577421927 0.1259403079198239 0.5401984919961202 +Segmental peripheral demyelination remyelination 2 7 1.995031825927591 0.0460394088540407 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 1.0 0.0550816697898294 0.1094892401774078 0.2559514735144251 0.1129571724371578 +Elevated creatine kinase after exercise 0 5 1.9738061029561536 0.0484037946369393 0.8786407766990292 4.587378640776699 0.5647545096972807 0.3862874988914485 1.1103354242992365 0.4923057719913678 1.111320921015603 0.2932479459149971 1.0 0.0279227766388577 0.0563150378970086 0.1373795195898598 0.2586577321272367 +Oromandibular dystonia 1 6 1.9603836421611824 0.0499509663317168 1.730582524271845 4.956310679611651 1.1882502597012077 0.2382412593757527 1.131086190944388 1.1979083634266432 0.9893427275402558 0.2482274576089271 1.0 0.0639684350193291 0.1265462710440741 0.0442367692127036 0.1462762019757018 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..66ab7ba2cd8a96961cbb416f7c64414307ab3715 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4656, + "title": "Average number of proteins per term", + "value": 25.007302405498283 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..270d6ad3cdcd4f24f4ff04e510211930c17e5f90 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4dd86ee4ee452960dda233c794da07572ac56d15 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1000 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Neoplasm of the skeletal system 0.5539451221147013 3.2930236498161447 0.0009911613705084 0.9901189439237832 0.2487303817854283 43 P48735,P62081,P62899,O75874,P62847,P54277,Q6PD74,Q13126,P42771,Q06124,P08708 11 +Micromelia 0.6724865913679972 3.261840445256923 0.001106914275387 0.994239018251267 0.2487303817854283 26 P48735,Q9UBM7,O75874 3 +Sarcoma 0.4863311278582192 3.178789068410816 0.0014789167039168 0.998983035417818 0.2487303817854283 62 P48735,P62081,Q02750,P62899,O75874,Q15645,Q15437,Q15392,Q13126,P42771,Q9UPY3,Q01844,P08708,Q9Y620 14 +Recurrent fractures 0.5775259192161801 3.0448762002822116 0.0023277610581633 0.9999806087630592 0.2487303817854283 31 P48735,Q96AY3,O75874 3 +Abnormal cartilage morphology 0.7509184921736793 2.9202922080966993 0.0034970331854553 0.9999999175210504 0.2487303817854283 14 P48735 1 +Venous thrombosis 0.7665489540527006 2.898239281839882 0.0037526416604412 0.9999999750193788 0.2487303817854283 13 P48735 1 +Abnormality of the parathyroid gland 0.6484915298321002 2.894918517985977 0.0037925696469063 0.9999999792718708 0.2487303817854283 23 P48735,O75874 2 +Macrocytic anemia 0.5364168763412983 2.8746057193663295 0.0040453231502755 0.9999999936399178 0.2487303817854283 34 P11586,P00374,P62899,P11172,P62081,P62847,P39019,P08708 8 +Pituitary adenoma 0.7394104100260017 2.8600927239150997 0.004235171578943 0.999999997381944 0.2487303817854283 14 P48735 1 +Neoplasm of the parathyroid gland 0.9513998730642834 2.8171797855259864 0.004844739783409 0.9999999998487258 0.2487303817854283 6 P48735 1 +Parathyroid adenoma 0.9513998730642834 2.8171797855259864 0.004844739783409 0.9999999998487258 0.2487303817854283 6 P48735 1 +Abnormality of the parathyroid morphology 0.9513998730642834 2.8171797855259864 0.004844739783409 0.9999999998487258 0.2487303817854283 6 P48735 1 +Glioma 0.6819035888208369 2.802182970139178 0.0050758077003358 0.9999999999486904 0.2487303817854283 17 P48735 1 +Ectrodactyly 0.6563976515791412 2.739720833761064 0.0061491389653696 0.999999999999663 0.2497936400924265 19 Q9UBC2,Q99720,Q96HP0,Q6DKJ4,P04792,Q9UBM7,O96028 7 +Cerebral palsy 0.7476042876695606 2.706114094545205 0.0068075652687138 0.9999999999999846 0.2497936400924265 12 P48735,O75874 2 +Astrocytoma 0.7384366055266968 2.6597219133971928 0.0078205192207314 1.0 0.2524687880878757 12 P48735 1 +Skin nodule 0.5954031093597705 2.6170666135083005 0.0088689031563515 1.0 0.2652822814803013 24 P48735,P34913 2 +Neoplasm of the pituitary gland 0.6462077497163263 2.595563149126503 0.0094436047601234 1.0 0.2697812069571104 17 P48735 1 +Early onset of sexual maturation 0.4572244065475027 2.5942085220408964 0.0094808965919852 1.0 0.2697812069571104 49 P48735,O75874,Q15056,Q9UBM7,O96028,P04150 6 +Neoplasm of the adrenal cortex 0.8452377670337006 2.593422235145757 0.0095026026505511 1.0 0.2697812069571104 7 P48735 1 +Skin ulcer 0.5385685814429937 2.577356059667381 0.0099559337205705 1.0 0.2782440349758646 29 P48735 1 +Goiter 0.7894992462251023 2.570424783640086 0.0101573881425038 1.0 0.2782440349758646 8 P48735,Q15437,O75874 3 +Abnormal erythrocyte enzyme level 0.6252165789677334 2.5521621487008894 0.0107056682213686 1.0 0.2847787996153664 19 P62081,P62899,P62847,P39019,Q96RL7,P08708,P60891 7 +Enchondroma 0.7772981158704654 2.5133581046345275 0.0119587874980076 1.0 0.3042629212607837 8 P48735 1 +Neoplasm of the breast 0.4953242675115776 2.500325076300525 0.0124079392110811 1.0 0.3072944945042234 32 P48735,O75874,Q15437,Q9NYB0,P42771,Q13535 6 +Genital neoplasm 0.462823829088689 2.468356530687265 0.0135735051078711 1.0 0.319283462077052 42 P48735,O75874,Q15645,Q15437,P42771,Q9UPY3,Q01844,Q9Y620 8 +Chondrosarcoma 0.9672029148600678 2.461099334988157 0.0138512010157101 1.0 0.319283462077052 4 P48735 1 +Abnormality of the alveolar ridges 0.7619062144805909 2.4408076473023987 0.0146544579642355 1.0 0.3197031044829261 8 O43924,Q15392,Q9UBM7 3 +Neoplasm of the adrenal gland 0.641569623374141 2.4270946366872046 0.0152202850270461 1.0 0.3206590365879055 15 P48735 1 +Vascular neoplasm 0.4637935392033594 2.4198985732688336 0.0155248366703364 1.0 0.3214363603047234 40 P48735,O75874,Q15437,Q9UBM7,O96028 5 +Bone pain 0.5658692167631576 2.4196996935713653 0.0155333292673029 1.0 0.3214363603047234 24 P48735 1 +Exostoses 0.9121663442386918 2.4073057859445046 0.0160707074522736 1.0 0.326747658942298 5 P48735 1 +Hamartoma 0.5694727679166264 2.384827465141966 0.017087133039068 1.0 0.3336358082465119 23 P48735 1 +Malignant neoplasm of the central nervous system 0.512280721274885 2.3795267929980057 0.0173348827717279 1.0 0.3336358082465119 29 P48735,O95155,O75874,Q15555,P42771 5 +Adenocarcinoma of the colon 0.5873662310817008 2.360539680159365 0.0182483659711345 1.0 0.3358276362118674 20 Q07864,P62081,P62899,P62847,P39019,Q6PD74,P08708 7 +Limb undergrowth 0.4118514805385613 2.357290104686242 0.0184088590090194 1.0 0.3367162896630606 60 P48735,O75874,Q15392,Q15125,Q9UBM7 5 +Rhizomelia 0.6783048933656813 2.3489225779974214 0.0188278212417865 1.0 0.3367162896630606 12 Q15125,Q9UBM7 2 +Platyspondyly 0.4627829659819497 2.3123082941367983 0.0207606999439311 1.0 0.3367162896630606 36 P48735,O75874 2 +Centrocecal scotoma 0.927657790071609 2.30579680557936 0.0211219888120552 1.0 0.3367162896630606 4 P03886 1 +Reticulocytopenia 0.5831731525211413 2.2927417324431474 0.021862878382038 1.0 0.3402070597091792 19 P62081,P62899,Q9BXW9,P62847,P39019,P08708 6 +Breast carcinoma 0.5366269496531453 2.2798774816257996 0.0226149559551418 1.0 0.3486597183017895 25 P48735,O75874,Q15437,P42771,Q13535 5 +Erythroid hypoplasia 0.5846954598244034 2.2635764677990338 0.023600176551846 1.0 0.3565747305116678 18 P62081,P62899,P62847,P39019,P08708 5 +Abnormal astrocyte morphology 0.5836544961019502 2.2571412699772595 0.0239992488068634 1.0 0.3565747305116678 18 P48735 1 +Ovarian neoplasm 0.5551517122706453 2.2414138988466616 0.0249992770420317 1.0 0.3617055047174749 22 P42771,P48735,Q01844,O75874 4 +Abnormality of the thenar eminence 0.5849275211511593 2.2288783991064864 0.0258219967207229 1.0 0.3710716565792777 17 P62081,P62899,P62847,P39019,P08708 5 +Multiple enchondromatosis 0.867408841133946 2.2249641926521755 0.0260836420391066 1.0 0.3725320163622099 5 P48735 1 +Sclerocornea 0.6898739869513286 2.203158813198711 0.0275835571047307 1.0 0.3814217241953956 9 Q9UBM7 1 +Gonadal neoplasm 0.4815953661797029 2.143424542073557 0.0320790241738722 1.0 0.3909341020088906 29 P42771,P48735,Q01844,O75874 4 +Partial duplication of the phalanx of hand 0.5586441881676998 2.1379365621684343 0.0325218922981067 1.0 0.3933037156882729 19 P62081,P62899,Q9BXW9,P62847,P39019,P08708 6 +Subcutaneous nodule 0.5558829801931612 2.120353417474633 0.0339762519804514 1.0 0.400207985488099 19 P48735 1 +Lymphangioma 0.9985392930178209 2.1203319487810792 0.0339780611679716 1.0 0.400207985488099 2 P48735 1 +Visceral angiomatosis 0.9985392930178209 2.1203319487810792 0.0339780611679716 1.0 0.400207985488099 2 P48735 1 +Hemangiomatosis 0.9985392930178209 2.1203319487810792 0.0339780611679716 1.0 0.400207985488099 2 P48735 1 +Hypothermia 0.6481103031929263 2.119655324365772 0.0340351231764994 1.0 0.400207985488099 11 O43772 1 +Neoplasm of the genitourinary tract 0.3749728301914494 2.1118438075791577 0.0346998484334681 1.0 0.4027963048066771 74 P48735,P62081,P62899,O75874,P62847,Q15645,P54277,Q15437,Q6PD74,Q92733,P42771,Q9UPY3,Q01844,P08708,Q9Y620 15 +Adenocarcinoma of the intestines 0.5274047133142057 2.1012895618270773 0.0356155554867756 1.0 0.4051807907948261 23 Q07864,P62081,P62899,P62847,P39019,Q6PD74,Q13043,P08708 8 +Dicarboxylic aciduria 0.5194054517470295 2.100593682730439 0.0356766490675477 1.0 0.4051807907948261 24 P48735 1 +Ventricular tachycardia 0.6294914103687073 2.0882786541048146 0.0367727058239113 1.0 0.4051807907948261 12 O43772,P0DP25 2 +Increased susceptibility to fractures 0.3973709818626452 2.0845461571986834 0.0371105162711062 1.0 0.4051807907948261 54 P48735,Q96AY3,O75874 3 +Neoplasm of the nervous system 0.3896512234711397 2.0772997875876285 0.037773898676443 1.0 0.4051807907948261 58 P48735,O95155,O75874,Q15555,Q15437,Q6PD74,P42771,Q9UPY3,Q9H9P8,Q01844,O43924 11 +Neck flexor weakness 0.8660509015286251 2.0587460843993672 0.0395185690062525 1.0 0.4125525948276046 4 Q99720 1 +Osteolysis 0.4596168580424685 2.0438271151167893 0.0409706294565146 1.0 0.4183316902402021 30 P48735 1 +Pure red cell aplasia 0.5393601294048859 2.0144884988218723 0.0439582711794761 1.0 0.4293593871470491 19 P62081,P62899,P00491,P62847,P39019,P08708 6 +Persistence of hemoglobin f 0.5367564587798946 1.997706443168935 0.0457484952766118 1.0 0.4347040694038872 19 P62081,P62899,P62847,P39019,P08708 5 +Abnormal urine ph 0.39988878563696 1.996646974443824 0.0458635461310099 1.0 0.4349097164683959 46 P48735,O43772 2 +Segmental peripheral demyelination remyelination 0.713551562627285 1.995031825927591 0.0460394088540407 1.0 0.4356900154967762 7 P03886,P07196 2 +Oromandibular dystonia 0.7499954416240162 1.9603836421611824 0.0499509663317168 1.0 0.4524741230359406 6 Q99720 1 +Bradycardia 0.6160856526609447 1.9489808136774711 0.0512977160325922 1.0 0.4601968513444114 11 O43772 1 +Hammertoe 0.5171454854104327 1.9450881644755296 0.051764368123286 1.0 0.460831544898699 21 Q9UBM7,Q99720 2 +Gastrointestinal carcinoma 0.4468092833882996 1.9402230452002045 0.0523525889863858 1.0 0.4642201671499739 30 Q07864,P62081,P62899,P46783,P62847,P39019,Q6PD74,Q13043,O14965,P08708,Q9Y620 11 +Coarctation of aorta 0.415541302767429 1.9180790731955353 0.0551009855188426 1.0 0.470734290964645 37 P62081,Q02750,P62899,P62847,Q15645,P37837,Q9UBM7,P08708 8 +Anarthria 0.7401002049627414 1.9161775042788107 0.055342505735574 1.0 0.4709600353531707 6 Q99720 1 +Osteosarcoma 0.4930100543254491 1.9148125139003356 0.0555164180006766 1.0 0.4709600353531707 24 P62081,P62899,Q13126,P42771,P08708 5 +Upper limb spasticity 0.6508222654925148 1.898738955349356 0.057598806945436 1.0 0.4754188129166298 8 Q99720 1 +Bulbar signs 0.5805590209292022 1.8983223740153123 0.0576536283683242 1.0 0.4754188129166298 13 Q99720 1 +Abnormality of the metaphysis 0.3772245175605059 1.890442445008252 0.0586988112564428 1.0 0.4759383320187502 55 Q13126,P48735,O75874 3 +Multiple lentigines 0.7337928568179508 1.887904351007747 0.0590387923326531 1.0 0.4759383320187502 6 Q06124,Q02750 2 +Abnormal thyroid morphology 0.4065059039519331 1.8778025722168497 0.06040817826702 1.0 0.4803966038714817 39 P48735,O75874,Q15437,P42771,Q9UPY3 5 +Mitochondrial respiratory chain defects 0.7842081876481459 1.8766544797680451 0.0605654653076803 1.0 0.4803966038714817 5 Q4J6C6,P03886 2 +Glioblastoma multiforme 0.6136518420123911 1.872682171668505 0.0611122866988709 1.0 0.4830879573343684 10 P42771,O75874 2 +Ependymoma 0.7269996631182377 1.8573717206498024 0.0632582869608315 1.0 0.4954657765667021 6 O75874 1 +Webbed neck 0.4075387407520062 1.84597873411776 0.0648952932793445 1.0 0.5010820655201128 37 P62081,Q02750,P62899,P62847,P39019,P41227,P36507,Q06124,O96028,P08708 10 +Caudate atrophy 0.9313467718375704 1.8444121416084291 0.0651230991802913 1.0 0.5011787599726224 2 P42858 1 +Ventricular arrhythmia 0.4078142113652574 1.8294900021731872 0.0673262356968729 1.0 0.5075592028110164 36 O43772,P0DP25,O75306,P03886,P46976 5 +Titubation 0.6009996600510933 1.805372166553086 0.0710164636165391 1.0 0.5142342995312693 10 Q99720 1 +Neoplasm by histology 0.3283016347543295 1.803175530608364 0.0713606520893748 1.0 0.5156790485242333 112 P48735,O95155,O75874,P42771,Q06124,Q9UPY3,Q15477,Q02750,P62847,Q15645,Q9NYB0,Q6PD74,Q13126,P07437,O43924,P62899,Q15437,P54277,P62081,Q15555,O95999,Q15392,Q01844,P08708,Q9Y620 25 +Neoplasm of the tracheobronchial system 0.9199532573765729 1.7971713964372211 0.0723084139823813 1.0 0.5156790485242333 2 P30154 1 +Ventricular preexcitation 0.6708665306681642 1.7926849989212392 0.073023306507562 1.0 0.5156790485242333 7 O75306,P03886 2 +Abnormality of the pituitary gland 0.3553824214308845 1.7821155445937022 0.0747303913950383 1.0 0.5170055012411567 62 P48735,Q9NVI1,P42356,O75874,Q9Y285,Q4J6C6,Q96IJ6 7 +Blurred vision 0.7579192783647758 1.7642616614829267 0.077687935530732 1.0 0.5254435623809361 5 P03886 1 +Organic aciduria 0.3865127238274934 1.7586179483841855 0.0786424223398669 1.0 0.5283681362401451 42 P48735 1 +Head titubation 0.6623475848618545 1.751857951879604 0.0797982363329001 1.0 0.5309696313691752 7 Q99720 1 +Tracheal stenosis 0.7525387396816721 1.7411344952271746 0.0816600060457219 1.0 0.535311951104991 5 Q9UBM7 1 +Abnormal thrombosis 0.4669665664065444 1.7286267469917016 0.08387591941423 1.0 0.5397508912297753 24 P48735 1 +Abnormal atrioventricular conduction 0.5641123213545151 1.7280485625272393 0.0839795182519693 1.0 0.5397508912297753 12 O43772 1 +Abnormal natural killer cell morphology 0.74644372470907 1.7148883050449073 0.0863657072292767 1.0 0.5485930871207536 5 O00203,P33991,Q13546 3 +Reduced natural killer cell count 0.74644372470907 1.7148883050449073 0.0863657072292767 1.0 0.5485930871207536 5 O00203,P33991,Q13546 3 +Finger swelling 0.8995033596260664 1.712115046504233 0.0868754690240944 1.0 0.5495817714350325 2 P28070 1 +Talipes calcaneovalgus 0.65139668724824 1.6991753908875422 0.0892861417203207 1.0 0.5532172185289917 7 Q9UBM7 1 +Neoplasm of the large intestine 0.3696876880310479 1.6964144241903805 0.0898074239596491 1.0 0.5532172185289917 46 Q07864,P62081,P62899,P46783,P62847,Q15645,P39019,P54277,Q6PD74,Q15437,P42771,Q9UPY3,Q13043,O14965,P08708,Q5HYI8,Q9Y620 17 +Vertebral wedging 0.891615541922298 1.6792279806385069 0.0931076207546004 1.0 0.557964784062198 2 Q96AY3 1 +Ventricular hypertrophy 0.3816601478001673 1.6679525110535518 0.0953251543043509 1.0 0.5619885564552931 40 P13807,O43772,P37837,P03886,P46976 5 +Abnormality of the female genitalia 0.2805912259451502 1.660120147778553 0.0968902844862471 1.0 0.5665537450417818 140 P48735,Q9NVI1,O95155,O75874,P42771,Q9UPY3,Q9UBM7,Q15645,Q15056,Q13535,O96028,Q15437,P37837,Q6DKJ4,P04150,Q15051,Q15392,Q01844,Q9Y620 19 +Malignant genitourinary tract tumor 0.4777926969489002 1.6435401491306512 0.1002712255574216 1.0 0.5725282238906131 20 P62081,P62899,P46783,P62847,P39019,P08708 6 +Disproportionate short limb short stature 0.4826115968847601 1.6430558561886133 0.1003713771012315 1.0 0.5725282238906131 19 Q15392,Q15125,Q9UBM7 3 +Personality changes 0.4903637949376536 1.634369106073099 0.1021813711151202 1.0 0.5743920791932706 17 P49770,Q14232,Q9NR50,Q96RL7,Q14203,P03886,P42858 7 +Erythema nodosum 0.8787613204791183 1.625555214981386 0.1040443089034046 1.0 0.5748874230744243 2 P98170 1 +Eyelid myoclonus 0.5669683157744686 1.6224068244115335 0.1047162689057739 1.0 0.5748874230744243 10 P00374 1 +Increased mean corpuscular volume 0.4691446555374757 1.6193236117289982 0.1053776529495844 1.0 0.5748874230744243 21 P62081,P62899,P62847,P39019,P08708 5 +Pancytopenia 0.3862736492239529 1.6190670174695672 0.105432844396752 1.0 0.5748874230744243 35 P00374,P98170,P37837,Q13535,Q96J02,O76094 6 +Joint stiffness 0.3437610017541868 1.612596085421301 0.1068322895117814 1.0 0.5790317346553281 60 P48735,Q96AY3,O95155,P15586,O75874 5 +Peripheral hypermyelination 0.8906381601096833 1.609098660626848 0.1075947700879238 1.0 0.5809274503584879 3 Q13614 1 +Panhypogammaglobulinemia 0.7171913161820291 1.588267608577575 0.112225838749365 1.0 0.5892667179558198 5 P18074,Q6PGP7,Q15477 3 +Epiphyseal stippling 0.5246994246738128 1.5769707921124894 0.1148022458685826 1.0 0.5892667179558198 13 Q9UBM7 1 +Acidemia 0.5364151021690803 1.5721122113941628 0.115924529980095 1.0 0.5892667179558198 12 P48735 1 +Abnormal blood phosphate concentration 0.5443944982509478 1.5570168665847948 0.1194664809653449 1.0 0.5961210718438464 11 Q01968,Q15813,P16930 3 +Abnormal circulating lipid concentration 0.3293532304146729 1.554697287089718 0.1200181810315008 1.0 0.5961552951180495 80 O43772,P34913,P98170,Q15392,Q15056,Q15125,P28070,Q9UBM7,P42858 9 +Abnormality of adrenal morphology 0.3995002140266047 1.5505168438147603 0.1210175138663669 1.0 0.5961552951180495 30 P48735,O75874 2 +Abnormal form of the vertebral bodies 0.3280854226152527 1.5496864510413657 0.1212167916878181 1.0 0.5961552951180495 87 P48735,Q96AY3,O75874,P15586,Q15125,Q9UBM7,O96028 7 +Torsade de pointes 0.857727139935737 1.5375654437016748 0.1241549021372034 1.0 0.601524687149656 2 P0DP25 1 +Neoplasm of the endocrine system 0.3583499653535142 1.5322822484740046 0.1254527996912644 1.0 0.6047600780372503 44 P48735 1 +Absent thumb 0.4396051303192153 1.5304661283400476 0.1259013913777513 1.0 0.6051182242468583 24 Q9NVI1,P62081,P62899,P46783,Q9BXW9,P62847,P39019,P08708 8 +B lymphocytopenia 0.655265717296003 1.5303248854092677 0.1259363314637469 1.0 0.6051182242468583 6 P50851,Q13546,Q7L590 3 +Neoplasm of the respiratory system 0.4775159663830912 1.5257178799498012 0.1270801396686667 1.0 0.6086065032216631 16 P30154,Q15645,P42771,Q9UPY3,Q01844 5 +Dysphagia 0.273520474345432 1.520932807894335 0.1282766998666951 1.0 0.6106377286185559 141 P48735,Q01105,P42356,O95155,O75874,Q99720,P15586,P07737,Q8N0X7,O75306,P03886,Q9HD42 12 +Spinal muscular atrophy 0.5261119308464285 1.5137049897966903 0.1301006788470637 1.0 0.6137175031516487 12 Q8TD16,P38935,Q99720 3 +Hypoplasia of the frontal lobes 0.5255215578943795 1.510352613421387 0.1309534732074277 1.0 0.6146551645773205 12 Q00534,Q9UBM7,P42695,O43379 4 +Hypokalemia 0.5451900897037047 1.5040453784946703 0.1325696829195268 1.0 0.6204063283405359 10 Q9UNF1,Q08426,P40818,P04150,Q01968,P0DP25 6 +Bifid scrotum 0.6468282724073225 1.491390384785432 0.1358590310650704 1.0 0.6256771994450723 6 Q9UBM7 1 +Amegakaryocytic thrombocytopenia 0.8454572012854238 1.486180869659541 0.137231286221954 1.0 0.6257473611871649 2 Q02750 1 +Reduced factor xii activity 0.8454572012854238 1.486180869659541 0.137231286221954 1.0 0.6257473611871649 2 Q02750 1 +Reduced factor xiii activity 0.8454572012854238 1.486180869659541 0.137231286221954 1.0 0.6257473611871649 2 Q02750 1 +Abnormal mean corpuscular volume 0.4394359416793568 1.4845053971451212 0.1376748923985216 1.0 0.6257473611871649 23 P62081,P62899,P62847,P39019,P08708 5 +Abnormality of hair growth 0.6034859561436405 1.4663793034074226 0.1425449815220321 1.0 0.6288420228927114 7 P04080,P36507,Q02750 3 +Schizencephaly 0.8396143733567126 1.4617059120414182 0.14382181647141 1.0 0.6311569576465674 2 O43379 1 +Abnormal head movements 0.5253733391569673 1.4511791886515009 0.1467299703725397 1.0 0.6369234266877617 11 Q99720 1 +Abnormality of coagulation 0.3262440141958487 1.4506176323031394 0.1468863626868284 1.0 0.6369234266877617 62 P48735,O75874,P98170 3 +Abnormality of the hypothalamus pituitary axis 0.3181343035016342 1.4504998087043932 0.1469191924962749 1.0 0.6369234266877617 68 P48735,Q9NVI1,P42356,O75874,Q9Y285,Q4J6C6,Q96IJ6 7 +Metatarsus adductus 0.4781443155261516 1.4486646268473795 0.1474312635330257 1.0 0.6373630111511306 15 Q9UBM7,O96028 2 +Upper limb asymmetry 0.8343558282208665 1.4396782253071962 0.149958456635177 1.0 0.640291573013803 2 Q15555 1 +Congenital hepatic fibrosis 0.5967604774728062 1.4334553138188344 0.1517277605560074 1.0 0.6420739222442752 7 Q96HP0 1 +Abnormal number of erythroid precursors 0.4262680103179313 1.4331796001674373 0.1518065179382948 1.0 0.6420739222442752 24 P62081,P62899,P00491,P46783,P62847,P39019,P08708 7 +Abnormality of the ovary 0.3192136642768862 1.426668323762337 0.1536755201833597 1.0 0.6446065062826332 65 P48735,P49770,Q01844,O75874,Q14232,Q15437,P54277,P40818,Q15056,P42771,Q06124,Q9UPY3,Q15051 13 +Abnormal platelet granules 0.8293894244814577 1.4188761005668968 0.1559351411039737 1.0 0.648823965129671 2 O00203 1 +Biparietal narrowing 0.5279170878107536 1.4096194558243471 0.1586520790010555 1.0 0.6509837700752595 10 P36507,O43924,Q02750,Q9UBM7 4 +Hypophosphatemia 0.5544653073722274 1.4051343479888296 0.1599813320088365 1.0 0.6516824862932136 8 Q01968,P16930 2 +Cardiac conduction abnormality 0.3660470853597507 1.398346481959838 0.1620090459374907 1.0 0.6564961861487877 32 O43772,P0DP25,O75306,P03886 4 +Decreased specific antibody response to protein vaccine 0.8235465965527341 1.394407853555817 0.1631944778672904 1.0 0.6595776813802989 2 P17812 1 +Iris coloboma 0.3640208102074668 1.3804798213148382 0.167438958397887 1.0 0.6657521693429223 32 O43505,Q9UBM7,O96028,Q96IJ6,P78318 5 +Stuttering 0.6678691095319971 1.372872917563184 0.1697918572358889 1.0 0.6688247777413697 5 P03886 1 +Albinism 0.829631794272359 1.3714851684644067 0.1702237638592765 1.0 0.6699592937690545 3 O00203,O14617 2 +Infertility 0.464988270363132 1.3666897924254386 0.1717225587050195 1.0 0.6723442824580693 15 Q02750,Q15645,Q86Y56,P40818,P04150 5 +Pleural effusion 0.4883209601057176 1.3640822269497168 0.1725416878123051 1.0 0.6723442824580693 13 Q02750,Q9UID3,Q06124,Q13043,P14174 5 +Arterial stenosis 0.4510010721104935 1.355425965369439 0.1752818815853034 1.0 0.6750309682888113 16 P34913 1 +Generalized hyperreflexia 0.6967347612987446 1.3530472647078575 0.1760405312653921 1.0 0.6762745161482389 4 P18074,P26639 2 +Decreased specific antibody response to vaccination 0.8237872589129218 1.3486952861098036 0.1774348602553166 1.0 0.6785745433830797 3 P50851,P17812 2 +Hypophosphatemic rickets 0.8106923751095645 1.3406116081449833 0.180046586407617 1.0 0.6790147969610261 2 P16930 1 +Low molecular weight proteinuria 0.8106923751095594 1.3406116081449635 0.1800465864076235 1.0 0.6790147969610261 2 Q01968 1 +Bicarbonaturia 0.8106923751095594 1.3406116081449635 0.1800465864076235 1.0 0.6790147969610261 2 Q01968 1 +Foot dorsiflexor weakness 0.3568423265123132 1.3403247534847569 0.1801397872588759 1.0 0.6790147969610261 34 Q99720,Q15813,Q9Y223,P04792,P38935,P46976 6 +Rhabdomyosarcoma 0.5247554709513343 1.339522822760396 0.1804005296767235 1.0 0.6790176767783546 9 P42771,Q9UPY3 2 +Supernumerary tooth 0.5416858396141139 1.3385738932045732 0.1807094297973892 1.0 0.6792863446880776 8 Q9UBM7 1 +Aplastic anemia 0.5412250918903301 1.3361716569360524 0.1814931728505087 1.0 0.6792863446880776 8 P98170 1 +Tachycardia 0.412322231197887 1.3311721205266738 0.1831323826480386 1.0 0.6810154423472558 24 O43772,P0DP25 2 +Cessation of head growth 0.5756972197577976 1.3300844837175272 0.1834904372172312 1.0 0.6812850683280931 7 P49770,Q9NR50,Q14232 3 +Retinal telangiectasia 0.61124040779124 1.3264881421213843 0.1846780602999742 1.0 0.6829714446041939 6 P03886 1 +Bifid tongue 0.6567077243711665 1.3239311560312137 0.1855259097474948 1.0 0.683511631088265 5 Q9UBM7 1 +Freckling 0.4811915176837001 1.3221686439764109 0.1861119998872227 1.0 0.683511631088265 13 P18074,P52701,Q9NYB0,P11802,P42771,Q06124 6 +Bruxism 0.5384406891047476 1.3216514176231011 0.18628425320831 1.0 0.683511631088265 8 Q96RL7,P42858 2 +Neck muscle weakness 0.4422701807496401 1.2991501937528618 0.1938923902801475 1.0 0.6925059039084352 16 Q99720 1 +Subcortical heterotopia 0.6839854559229078 1.298984501631516 0.1939492480018469 1.0 0.6925059039084352 4 P23258,P43034 2 +Subcortical band heterotopia 0.6839854559229078 1.298984501631516 0.1939492480018469 1.0 0.6925059039084352 4 P23258,P43034 2 +Abnormal circulating cholesterol concentration 0.3533463411764235 1.2971826346843525 0.1945683542261729 1.0 0.6935740466938073 33 Q15392,Q15125,Q9UBM7,P34913 4 +Osteomalacia 0.6505411716016898 1.2968795881303437 0.1946726207380333 1.0 0.6935740466938073 5 Q01968 1 +Rickets 0.5669506789639881 1.2870814289983614 0.1980659076133624 1.0 0.6974802203378815 7 Q01968,Q08426,Q9NSD9,P16930 4 +Abnormal blood potassium concentration 0.4635782711429146 1.2854414844596829 0.1986380524415874 1.0 0.6974802203378815 14 Q9UNF1,Q9H4A3,Q08426,P40818,P04150,Q01968,P0DP25 7 +Aplasia hypoplasia of the skin 0.3160970227448838 1.2723735291033005 0.2032404346550542 1.0 0.7017163149541028 58 Q9H4L7,Q96HP0,Q13126,Q15125,O96028,Q96PU5 6 +Neoplasm of striated muscle 0.5027840013864185 1.271661420458399 0.2034934436201509 1.0 0.7017163149541028 10 P42771,Q9UPY3 2 +Cortical cataract 0.8036145486297621 1.2700967573918664 0.2040501665413119 1.0 0.7017163149541028 3 Q01968 1 +Oligomenorrhea 0.5281761954182688 1.2680888484324455 0.2047662234316445 1.0 0.7017163149541028 8 P04150,P40818,P31751 3 +Abnormal circulating monocarboxylic acid cocentration 0.5620245757752913 1.2628517489016826 0.2066424631361245 1.0 0.7017163149541028 7 Q7Z2Z2,Q9UDY2,P61011,Q9Y3A5,P37837,Q9H3U1 6 +Somatic mutation 0.3260785138050707 1.262628246560511 0.2067228117135013 1.0 0.7017163149541028 47 P30154,O75874,Q92733,Q01844,Q9Y620 5 +Unusual fungal infection 0.4914157800369675 1.2611661129994147 0.2072490049132229 1.0 0.7028050741995383 11 Q9Y5L0,O00203,Q13043,P40818 4 +Heart block 0.4079082557797656 1.2584735968593157 0.2082205301005975 1.0 0.7035375821105819 23 O43772,P0DP25 2 +Abnormal natural killer cell physiology 0.6730036096640788 1.2524208965418526 0.2104165358420058 1.0 0.7072326749477422 4 P98170 1 +Abnormality of small intestinal villus morphology 0.5597106536034782 1.251469188792618 0.2107633480601567 1.0 0.7072326749477422 7 P50851,Q6PGP7,P34949,P42224,Q15477 5 +Patchy changes of bone mineral density 0.7987580164982171 1.2511981998045572 0.2108621748605919 1.0 0.7072326749477422 3 Q13126 1 +Calvarial skull defect 0.5248762863264924 1.2508615189336667 0.2109850054773225 1.0 0.7072326749477422 8 Q96HP0 1 +Head tremor 0.45764431491989 1.2494774313234978 0.2114905030670413 1.0 0.7077355389551965 14 Q96RL7,Q99720 2 +Duplication of thumb phalanx 0.4055748794928256 1.2417301846790163 0.2143361291621115 1.0 0.7113582246264386 23 P62081,P62899,Q9BXW9,P62847,P39019,P41227,P08708 7 +Bilateral talipes equinovarus 0.5554389788491831 1.2304556943403828 0.2185265084309873 1.0 0.714309855235601 7 Q15125 1 +Heparan sulfate excretion in urine 0.6651533864953977 1.2191534549125616 0.2227859542904622 1.0 0.7208418368147269 4 P08236,P15586 2 +Short thumb 0.3341646157733731 1.2178226475705316 0.2232913760149388 1.0 0.7216994762131304 40 Q9NVI1,P62081,P62899,Q9UBM7,O96028,P08708 6 +Suicidal ideation 0.789511399651721 1.2152540458256764 0.2242692129924579 1.0 0.7236295604247291 3 P42858 1 +Cavernous hemangioma 0.583134740479329 1.1958972280897051 0.231736667004661 1.0 0.7325962550007095 6 Q15437,Q8NCE2,Q02750 3 +Abnormal gastrointestinal motility 0.3498132229417479 1.1925235928453206 0.2330560054955475 1.0 0.7325962550007095 31 P16930,P42771,Q9UBM7,Q01844,P03886 5 +Myofibrillar myopathy 0.626317625884057 1.1906401862253908 0.2337948684508641 1.0 0.7325962550007095 5 O75190,Q9Y281,O95817 3 +Abnormal enchondral ossification 0.3630743400723313 1.1901322352683972 0.2339944222536334 1.0 0.7325962550007095 29 Q15125,Q9UBM7 2 +Aplasia hypoplasia of the proximal phalanges of the hand 0.7735904177621952 1.185916801928575 0.2356551571593867 1.0 0.7349031558835263 2 Q9BXW9 1 +Dilation of virchow robin spaces 0.7732982763657626 1.1847040513516096 0.23613448008252 1.0 0.7359050463615885 2 P43034 1 +Unsteady gait 0.3098643291450985 1.1782522797187889 0.2386960460333178 1.0 0.7374709955747365 56 Q9GZZ9,O95831,P49770,Q2TAL8,Q14232,Q96C86,Q9NR50,Q12873,Q14738,Q9H6K4,Q13144,P07196,Q16512,Q7Z460,Q05639,P42858 16 +Abnormal erythrocyte sedimentation rate 0.4941928217865671 1.1747230647362892 0.2401055286336184 1.0 0.7379084761175759 9 P14174,P28070,P51617 3 +Colitis 0.4664502463214867 1.173155972655419 0.2407332640036874 1.0 0.7383755449283061 12 P50851,O95999,P98170,P42224,Q13043,Q15477 6 +Cardiac arrest 0.3542224723160782 1.1718096973474663 0.2412734684669748 1.0 0.739545272667699 30 O43772,P0DP25 2 +Acute kidney injury 0.6216374269005798 1.1701367535130025 0.2419459399270174 1.0 0.7407518410756072 5 P60891,P07741,P00338,P00492 4 +Malignant hyperthermia 0.6530254311605012 1.167814755100749 0.2428814950346163 1.0 0.7407518410756072 4 P36871,Q8NCE2,O95163 3 +Coxa vara 0.4435211387998832 1.1639083497864524 0.2444611554393212 1.0 0.7407518410756072 14 Q99575,Q96AY3,P26373,O95831 4 +Developmental glaucoma 0.3656888453061188 1.159679140910854 0.2461794658749407 1.0 0.7414046527255655 28 P62081,P62899,P62847,P39019,Q9Y3Z3,Q01968,A1X283,P08708 8 +Asymmetric growth 0.452468355456507 1.1532005371792486 0.2488280830956206 1.0 0.7465239673828135 13 Q15555,O95155,P31751,Q93008,O00232,Q15125,P07437 7 +Abnormality of bone marrow cell morphology 0.3081384049086774 1.1481319908578362 0.2509140794804363 1.0 0.7497934122144514 55 Q9NVI1,P00374,P98170,P37837,Q13535,Q96J02,O76094 7 +Biliary cirrhosis 0.5380521917677163 1.1449692694117837 0.2522218875138309 1.0 0.7497934122144514 7 Q9Y5L0,Q9UJW0,P14174,P21266 4 +Aplasia hypoplasia of the radius 0.4076261144405909 1.1402092191181186 0.2541991475758713 1.0 0.7522160430357322 19 Q13535,Q96AY3,Q9UBM7 3 +Ileus 0.6464409606286261 1.139984001433057 0.254292966438626 1.0 0.7522160430357322 4 Q01844,P16930 2 +Abnormal internal genitalia 0.2681391328282847 1.1371120007969853 0.2554914677228566 1.0 0.7529781180581097 125 P48735,Q9NVI1,Q01844,O75874,Q15437,Q15645,Q15056,P42771,Q9UPY3,Q9UBM7,O96028,P13051,Q15051,Q9Y620 14 +Hypoplastic hippocampus 0.7665108123904303 1.1261438732229243 0.2601046260849307 1.0 0.758801465571076 3 Q9UID3,Q96RL7 2 +Basal ganglia calcification 0.4761377247087625 1.125240712594331 0.2604870453304484 1.0 0.7594412542633486 10 Q9Y3Z3,P03886 2 +Abnormal muscle glycogen content 0.6414290550121677 1.118825683709225 0.2632145123404061 1.0 0.7632787758761285 4 P46976 1 +Ulnar claw 0.6390060400678006 1.1086057409741332 0.2676003004182814 1.0 0.7667279336481893 4 P04792 1 +Metaphyseal cupping 0.6373689247869666 1.101704247783315 0.2705902696547322 1.0 0.7667279336481893 4 Q14739,O95831 2 +Panniculitis 0.4962302749147506 1.1014003823923806 0.2707224390909404 1.0 0.7667279336481893 8 P28070,Q9Y3Z3 2 +Recurrent upper and lower respiratory tract infections 0.7531405200116992 1.1013189362510656 0.2707578724618393 1.0 0.7667279336481893 2 P13051 1 +Abnormal circulating progesterone level 0.5625999138748274 1.100635219296875 0.2710554507699569 1.0 0.7667279336481893 6 P49770,Q9NR50,Q14232 3 +Decreased circulating progesterone 0.5625999138748274 1.100635219296875 0.2710554507699569 1.0 0.7667279336481893 6 P49770,Q9NR50,Q14232 3 +Macular coloboma 0.7525562372188159 1.098911765642112 0.2718065541518906 1.0 0.7667561845053635 2 P60891 1 +Limb dystonia 0.4097986152109656 1.0898790637999745 0.2757664201568541 1.0 0.7725441950964578 16 Q99720 1 +Perisylvian polymicrogyria 0.6023484858475832 1.0858104919333869 0.2775628435576376 1.0 0.7740705889363241 5 Q15042,P42356,Q9BVA1 3 +Duplication involving bones of the feet 0.3837297610009136 1.085347469730631 0.27776778879204 1.0 0.7740705889363241 23 Q15125,Q9UBM7,O96028 3 +Thrombocytosis 0.3501898652235859 1.0852576655941892 0.2778075502819153 1.0 0.7740705889363241 29 P11586,P62081,Q6PGP7,P62899,P46783,P62847,P39019,P08708,Q15477 9 +Onychomycosis 0.7475898334794122 1.0784763677539029 0.2808212225523685 1.0 0.7759932740036228 2 P40818 1 +Abnormality of the breast 0.2814380080544315 1.0778837515492905 0.2810856374651995 1.0 0.7759932740036228 109 P48735,Q15555,O75874,Q15437,Q9NYB0,Q6PD74,P42771,Q13535,Q9UBM7,O96028 10 +Abnormality of female external genitalia 0.3193505949096162 1.0777076808873651 0.2811642296486494 1.0 0.7759932740036228 40 O95155,Q15392,Q13535,Q9UBM7,P04150 5 +Impaired adp induced platelet aggregation 0.7538145232789774 1.077206678156843 0.2813879424770724 1.0 0.7761506280647211 3 O00203 1 +Lymphopenia 0.3611104403432364 1.0765366726426957 0.2816873088917071 1.0 0.7765163470691465 27 P11586,P50851,P26038,P00491,Q7L590,P42224,P28070,Q13043,P51617,Q15477,Q13546,P17812 12 +Macrogyria 0.5570490831974395 1.0749477250707296 0.2823981331304348 1.0 0.7765788312695079 6 Q15392 1 +Abnormal epiphyseal ossification 0.4044082233944908 1.0744441979857893 0.2826236422158383 1.0 0.7765788312695079 17 Q9UBM7 1 +Impaired visuospatial constructive cognition 0.4753227454368259 1.0730977558509525 0.2832272577970141 1.0 0.7770807968785489 9 P03886 1 +Immunodeficiency 0.2889011343019425 1.0712527219423584 0.2840558115644302 1.0 0.7788950875406286 65 P98170,Q13043,Q15477,P60891,P50851,Q15813,O96028,P14174,O14646,P17812,Q07864,P46109,Q15437,P40818,O14617,P00491,O95999,Q9UJW0,P21266,P13051 20 +Gingival fibromatosis 0.6273189410925637 1.059409360913025 0.2894133883568446 1.0 0.7860214177738784 4 Q15392 1 +Recurrent bacterial infections 0.395331750708643 1.0577958759795314 0.2901485133784867 1.0 0.7860214177738784 19 Q15813,Q86Y56,O00203,Q13043,P13051 5 +Ambiguous genitalia 0.368809262253516 1.0511251780355044 0.2932011016581486 1.0 0.7871346791746247 25 Q15392,Q9UBM7,P04150 3 +Abnormal circulating ceruloplasmin concentration 0.7462606968992959 1.0482002184523076 0.2945463699363049 1.0 0.7884183334032205 3 Q8N511 1 +Colorectal polyposis 0.4705942491082761 1.0476967520862406 0.2947783444577241 1.0 0.7884183334032205 9 P42771,Q15437,Q9UPY3 3 +Coloboma 0.3048360395195162 1.046904691488103 0.2951435378848863 1.0 0.7884183334032205 47 O43505,O15347,Q96EK5,Q9UBM7,O96028,Q96IJ6,P78318 7 +Mixed demyelinating and axonal polyneuropathy 0.5924652004506131 1.042762425774965 0.2970583376236746 1.0 0.7884183334032205 5 P03886 1 +Myositis 0.4608019389251679 1.041236086397566 0.2977659914403945 1.0 0.7886225575349698 10 P28070,Q9Y3Z3,Q969U7 3 +Brittle hair 0.4126621296653937 1.040209996017483 0.2982423484238312 1.0 0.7891014151596836 15 P18074,Q02750,Q6PGP7,P49589,P36507,P62266,Q15436,Q15477 8 +Generalized hypopigmentation 0.4600346033603242 1.0370430031027478 0.2997158162792064 1.0 0.7891014151596836 10 Q01968,O00203,O14617,Q15477 4 +Nevus 0.3247825205156399 1.0353746591395874 0.3004939754240741 1.0 0.7900056180544828 32 Q96AY3,Q15437,Q9NYB0,Q15056,P42771 5 +Aplasia hypoplasia involving forearm bones 0.3762392015966362 1.0320183995496068 0.3020634981214849 1.0 0.7912664381576222 23 Q13535,Q96AY3,Q9UBM7 3 +Wide intermamillary distance 0.3840738835330428 1.0307445337177146 0.3026606349645004 1.0 0.7912664381576222 21 Q96EK5,Q06124,Q9UBM7,Q15555 4 +Abnormal parietal bone morphology 0.6203667628285272 1.0302353531379451 0.302899537726006 1.0 0.791414280388487 4 P39019,Q06124 2 +Chorioretinal dysplasia 0.5885912651590337 1.0259279926139977 0.3049255268496256 1.0 0.7946051134137978 5 O43505 1 +Facial erythema 0.740320414764053 1.0254555218575585 0.3051483019426997 1.0 0.7946051134137978 3 P40818 1 +Periventricular cysts 0.5135357757661558 1.024845172392694 0.3054362481600505 1.0 0.7946051134137978 7 O96028,Q9Y285 2 +Self mutilation 0.44030253979594 1.02420628561792 0.3057378505049302 1.0 0.7946051134137978 12 P41227,Q96RL7,Q9UBM7 3 +Abnormal vertebral morphology 0.2751516571822029 1.024016677722133 0.3058273976025614 1.0 0.7946051134137978 112 P48735,Q9NVI1,Q96AY3,O75874,P15586,Q6DKJ4,Q15056,Q15125,Q9UBM7,O96028,Q96J02,Q01968,O95831 13 +Central primitive neuroectodermal tumor 0.6182470219838584 1.0213557099185049 0.3070859410119406 1.0 0.7952125369030009 4 P42771 1 +Abnormal blood chloride concentration 0.7390809322132232 1.0207175390451049 0.3073882824075515 1.0 0.7952616352113231 3 Q9H4A3 1 +Hyperchloremic acidosis 0.7387887054452513 1.0196008978756614 0.3079177790036616 1.0 0.7955966587353209 3 Q9H4A3 1 +Congenital diaphragmatic hernia 0.3779804720929673 1.0154723437845965 0.3098807232876051 1.0 0.798453042405694 22 Q9UBM7 1 +Disproportionate short stature 0.3585809307148367 1.0145350751680642 0.3103275014997071 1.0 0.798662340041149 26 Q15125,Q9UBM7 2 +Diaphragmatic weakness 0.5435043275145174 1.0124428839587407 0.3113263428102435 1.0 0.7999643775521489 6 O95817 1 +Amyotrophic lateral sclerosis 0.3946519049219589 1.0110774453134612 0.3119793644982971 1.0 0.8003173119030697 17 Q99720 1 +Parietal foramina 0.7306456324861258 1.0091415677007776 0.3129067451346212 1.0 0.8011197205306526 2 P39019 1 +Abnormality of the foot musculature 0.6146884463737972 1.0064665693252612 0.3141911852362731 1.0 0.8013645850062474 4 Q8NCE2 1 +Uncombable hair 0.7280163599182079 0.9984428417732056 0.31806466798785 1.0 0.8063336077064563 2 Q15477 1 +Monochromacy 0.7277242185217658 0.9972551843154092 0.3186406609509862 1.0 0.8063336077064563 2 A2RRP1 1 +Overlapping fingers 0.4519427529300112 0.9929033339310132 0.3207570649128246 1.0 0.8072675103968171 10 Q15125,Q8TD16,P42356 3 +Clubbing 0.3784408777633468 0.9920663553157536 0.3211651575026097 1.0 0.8078317356658257 21 P50851,Q9NVI1,Q9H4L7,Q86TI2,Q9UID3 5 +Triphalangeal thumb 0.370264906940061 0.9896573617824244 0.3223416223747932 1.0 0.8085397189653694 23 Q9NVI1,P62081,P62899,Q9BXW9,P62847,P39019,P08708 7 +Oculogyric crisis 0.4408036062323149 0.9784445076376084 0.3278545244240827 1.0 0.814997685914858 11 P61457,Q01105,P35270 3 +Abnormal b cell morphology 0.4485372292031083 0.9743751351731936 0.3298703107338174 1.0 0.8182611437275727 10 P50851,Q13546,P17812,Q7L590 4 +Autoimmune antibody positivity 0.4390597632322343 0.9687879668372954 0.3326509916158273 1.0 0.8216567729248234 11 Q9Y5L0,P53621,Q96J02,P51617,Q13546 5 +Polyphagia 0.4557242215774001 0.9680964681262948 0.3329961936213237 1.0 0.8220733178689731 9 Q4J6C6,O95155 2 +Portal fibrosis 0.6046289645523211 0.9645108603934552 0.3347898661442161 1.0 0.8224077114316125 4 P55263,P06737 2 +Cardiac diverticulum 0.5742691407571098 0.9639256617318382 0.335083197125658 1.0 0.8224077114316125 5 P54277,Q16658,P52701 3 +Synovitis 0.72394406625336 0.9630998228048996 0.335497430695816 1.0 0.8224077114316125 3 Q02750 1 +Melanocytic nevus 0.4282670549573021 0.9561639725228176 0.338989398621675 1.0 0.8237654697194775 12 Q15437,Q96AY3 2 +Broad eyebrow 0.4186904403396394 0.9557697679601006 0.3391885653465853 1.0 0.8238194889169023 13 O14646,Q9NXH9 2 +Corneal opacity 0.288155753005798 0.9547090512643902 0.3397248513273978 1.0 0.8241430409306525 57 O43505,P34913,Q15645,Q15813,Q15056,Q9UBM7,O96028 7 +Subvalvular aortic stenosis 0.6009203567943626 0.9490981961659692 0.3425706717561572 1.0 0.8248202494349608 4 Q15645 1 +Abnormal left ventricular outflow tract morphology 0.6009203567943626 0.9490981961659692 0.3425706717561572 1.0 0.8248202494349608 4 Q15645 1 +Trichorrhexis nodosa 0.7200467562828737 0.948344862286024 0.3429539192215114 1.0 0.8248202494349608 3 Q6PGP7,Q15477 2 +Fatiguable weakness of proximal limb muscles 0.6007290959391036 0.9483042016249362 0.3429746125221116 1.0 0.8248202494349608 4 P06753,Q92734 2 +Adrenal overactivity 0.5293577616425219 0.9475190434401064 0.3433743570366951 1.0 0.8248202494349608 6 P04150 1 +Reduced antithrombin iii activity 0.6004814841093262 0.9472764029508476 0.3434979518158052 1.0 0.8248202494349608 4 P34949 1 +Focal t2 hyperintense brainstem lesion 0.384338574379729 0.9444608110264096 0.3449342188586446 1.0 0.8255630852968725 17 Q9NPL8,P03886 2 +Overlapping toe 0.3543044918902523 0.9442503176677336 0.3450417476925083 1.0 0.8255630852968725 25 Q9UBM7 1 +Abnormal platelet function 0.5278921008367832 0.9408185914533472 0.3467978318111901 1.0 0.8265141951109339 6 O00203,Q06124 2 +Speech apraxia 0.3320849426335375 0.939272592173656 0.3475908066893658 1.0 0.8265141951109339 29 Q12873,Q9NXH9,O00232,Q96PZ0,Q9Y296,Q8N0X7,Q7Z6Z7,O14646,Q8N806,P51570,P42858 11 +Abnormal lung lobation 0.4151750949640178 0.9354120971725134 0.3495759649719743 1.0 0.8265141951109339 13 Q9UBM7 1 +Abnormality of vitamin k metabolism 0.5672514619882982 0.933705208333166 0.3504559776326208 1.0 0.8265141951109339 5 Q7Z2Z2,Q9UDY2,P61011,Q13043 4 +Abnormality of vitamin a metabolism 0.5672514619882959 0.9337052083331548 0.3504559776326266 1.0 0.8265141951109339 5 Q7Z2Z2,P61011,Q9NSD9,Q13043 4 +Small anterior fontanelle 0.7161415892917132 0.9335963957336804 0.3505121252287702 1.0 0.8265141951109339 3 Q13535 1 +Tiger tail banding 0.7159382904067827 0.9328296332815084 0.3509079384443021 1.0 0.8265141951109339 3 P18074 1 +Abnormal mean corpuscular hemoglobin concentration 0.7159382904067827 0.9328296332815084 0.3509079384443021 1.0 0.8265141951109339 3 P18074 1 +Concave nail 0.7159382904067827 0.9328296332815084 0.3509079384443021 1.0 0.8265141951109339 3 P18074 1 +Increased mean corpuscular hemoglobin concentration 0.7159382904067827 0.9328296332815084 0.3509079384443021 1.0 0.8265141951109339 3 P18074 1 +Low set nipples 0.7159382904067827 0.9328296332815084 0.3509079384443021 1.0 0.8265141951109339 3 P18074 1 +Arthrogryposis multiplex congenita 0.3052577248493177 0.9328141913581984 0.3509159126846572 1.0 0.8265141951109339 39 Q15392,Q96AY3,P42356,Q9HD42 4 +Paroxysmal involuntary eye movements 0.3796190620317059 0.9327184763440316 0.3509653426736443 1.0 0.8265141951109339 18 Q9NPL8,P03886 2 +Abnormal size of the clitoris 0.3763639617022509 0.931637235668486 0.3515240329754387 1.0 0.8265141951109339 19 Q13535,Q9UBM7 2 +Type i diabetes mellitus 0.4140319928293134 0.9288031636273716 0.3529911046466552 1.0 0.8265370902114484 13 P50851,P03886,Q96J02 3 +Increased circulating igm level 0.4482877899903849 0.9284989165799395 0.3531488295341707 1.0 0.8265370902114484 9 P13051,P98170 2 +Aplasia cutis congenita 0.4394240733515819 0.92496456279666 0.3549843410402098 1.0 0.8265370902114484 10 Q96HP0 1 +Soft tissue sarcoma 0.3088264302368382 0.9215526215216828 0.3567619812855731 1.0 0.8265370902114484 35 Q15645,Q15437,Q15392,Q13126,P42771,Q9UPY3,Q9Y620 7 +Hand polydactyly 0.3062617573318422 0.9187278927055575 0.3582379166227132 1.0 0.8265370902114484 37 Q15125,Q9UBM7,O96028 3 +Abnormal reticulocyte morphology 0.3108042636033616 0.9142805967013896 0.360569423465475 1.0 0.8265370902114484 32 P62081,P62899,Q9BXW9,P62847,P39019,Q15437,P08708 7 +Abnormality of hair pigmentation 0.3595047693759601 0.9138673577170026 0.3607865475717933 1.0 0.8265370902114484 23 Q13126,O00203,Q9UBM7,O14617,Q15477 5 +Skin rash 0.3592073056482635 0.9117830232475777 0.361882948912158 1.0 0.8265370902114484 23 P28070 1 +Thickened helices 0.4425478885699967 0.898057172039785 0.3691550702200941 1.0 0.8300124074224606 9 Q06124,Q02750 2 +Abnormal lymphocyte morphology 0.3026711709891628 0.8865241359418711 0.3753351540332064 1.0 0.8325681168073411 37 P11586,P50851,P26038,Q13546,P00491,P98170,Q7L590,O95999,P42224,P28070,O00203,Q13043,P51617,Q15477,P33991,P17812 16 +Palmar telangiectasia 0.6999707858603663 0.8855635181348328 0.3758527776832321 1.0 0.8333193013776803 2 Q13043 1 +Neoplasm of the colon 0.2982693958403152 0.881133754600838 0.3782454294227833 1.0 0.8342542488832208 40 Q07864,P62081,P62899,P46783,P62847,Q15645,P39019,P54277,Q6PD74,P42771,P08708,Q5HYI8 12 +Diffuse cerebellar atrophy 0.483482141119911 0.8791628090479495 0.3793130063383376 1.0 0.8347224642094472 7 P18074,Q9HA77,Q12756,P26639 4 +Abnormal circulating aromatic amino acid concentration 0.5541372619238172 0.8775777471310842 0.3801729098614608 1.0 0.8347224642094472 5 P35270,P16930 2 +Periventricular heterotopia 0.4044936109766299 0.8738899668436042 0.3821781791296255 1.0 0.8347224642094472 13 Q9UBM7 1 +Primary gonadal insufficiency 0.4519302697914226 0.8725702781152148 0.3828973466940839 1.0 0.835021098926302 8 P49770,Q9NR50,Q14232 3 +Cerebellar cyst 0.2926860923955214 0.870453520302094 0.3840526093107401 1.0 0.8360414009215981 43 O43505,Q96HP0,Q9UID3,Q15125,Q9UBM7 5 +Laryngeal dystonia 0.6992986557568628 0.8704467964729095 0.3840562823693352 1.0 0.8360414009215981 3 Q96RL7,P04350 2 +Abnormality of the pulmonary veins 0.4812796508639955 0.8685918439611315 0.3850704171172996 1.0 0.8366252272973155 7 Q15392 1 +Painless fractures due to injury 0.6950043821209598 0.8658475150655068 0.3865737884569462 1.0 0.8392514243778517 2 Q9H4A3 1 +Abnormal levels of alpha fetoprotein 0.4806456766857678 0.8655523466502675 0.3867356977977405 1.0 0.8392514243778517 7 Q01968,O95999,P16930 3 +Holoprosencephaly 0.4026879524433602 0.8635463911968245 0.3878371244344822 1.0 0.8401186887737011 13 Q9UBM7 1 +Thoracolumbar scoliosis 0.4499940719901357 0.8627002761103018 0.388302280550044 1.0 0.8401186887737011 8 Q99575,P27635,P78318,Q93008 4 +Abnormal fingertip morphology 0.3033190985102826 0.8571215880291637 0.3913776915221134 1.0 0.8414830389688889 33 P50851,P46821,Q86TI2,P41227,Q9NXH9,Q96PZ0,Q9Y296,P62266,Q7Z6Z7,O14646,P42858 11 +Normochromic anemia 0.3549692747804451 0.8564049514808727 0.3917738268133299 1.0 0.8414830389688889 22 P62081,P62899,P62847,P39019,P08708 5 +Abnormality of taste sensation 0.6952074810052498 0.8552320394712946 0.3924227022817939 1.0 0.8419908303336554 3 Q9H4A3,O95163 2 +Abnormality of the lymph nodes 0.2851570070609314 0.8465025011223272 0.3972724791752933 1.0 0.842038351228631 46 P50851,Q13546,P00491,O95999,P98170,Q01844,Q15645,Q969U7,P42771,P28070,P13051,P14174,P51617,P33991 14 +Abnormality of the lymphatic system 0.2462499769074809 0.8448423852482718 0.3981988460569079 1.0 0.842038351228631 159 P48735,O95155,O75874,P15586,P98170,P36507,P16930,P42771,Q9UP83,Q06124,P28070,Q13043,Q96J02,P51617,Q15477,P50851,P83436,Q7L590,Q15645,Q9NYB0,Q9Y3Z3,O96028,P14174,Q5HYI8,P33991,P06744,P11172,P34949,Q15437,Q969U7,P37837,O00203,O14617,Q13546,P00491,Q9Y285,O95999,Q15392,Q96RL7,Q86Y56,Q9Y223,P13051,Q01844 43 +Cerebral hypoplasia 0.3659765976141073 0.8443944282359521 0.3984490348465952 1.0 0.842038351228631 18 Q00534,Q9UBM7,P42695,O43379 4 +Dysuria 0.4755137099871706 0.8410048075135497 0.4003452411722206 1.0 0.842038351228631 7 O00170,P08397,Q8N0X7 3 +Slow decrease in visual acuity 0.4453107635988266 0.8388915011275359 0.4015301974413101 1.0 0.842038351228631 8 P03886 1 +Minicore myopathy 0.6879929886065039 0.8381755852544283 0.401932096939912 1.0 0.842038351228631 2 P51114 1 +Increased nuchal translucency 0.3697971286685051 0.8356076219537132 0.4033756794549616 1.0 0.842038351228631 16 Q9UBM7,Q15056 2 +Abnormal metatarsal morphology 0.3243305392222956 0.8349884360945286 0.4037242193599597 1.0 0.842038351228631 28 Q15392,Q9UBM7,O96028 3 +Pectus excavatum of inferior sternum 0.6894765354437494 0.834009401365633 0.4042756860997787 1.0 0.842038351228631 3 Q02750 1 +Anemia of inadequate production 0.2656474763742533 0.833940753106587 0.4043143709170547 1.0 0.842038351228631 67 P00374,P62899,P62081,Q9Y285,Q15437 5 +Diaphragmatic paralysis 0.5437472702884427 0.8334882392996817 0.4045694279016862 1.0 0.842038351228631 5 O95817 1 +Abnormal brainstem mri signal intensity 0.3582268537677096 0.8328241208121967 0.4049439289529688 1.0 0.842038351228631 20 O75306,Q9NPL8,Q969Y2,P03886 4 +Abnormality of the musculature of the hand 0.2952030418309751 0.8301943950080878 0.4064288837308754 1.0 0.842038351228631 38 P62081,P62899,P62847,Q9Y223,P08708,P07196,Q96IJ6,Q8TD16 8 +2 3 toe syndactyly 0.2998057246984851 0.8270484138824499 0.4082096212361619 1.0 0.842038351228631 33 Q15125,Q9UBM7 2 +Multicystic kidney dysplasia 0.3602876037039871 0.8262633337403185 0.4086547281356245 1.0 0.842038351228631 19 Q15645,Q9UBM7 2 +Biconcave vertebral bodies 0.5414652813080161 0.8238557317523971 0.4100215362531734 1.0 0.842038351228631 5 Q96AY3,P40818 2 +Low set posteriorly rotated ears 0.2686826144800321 0.823141621891215 0.4104274620688337 1.0 0.842038351228631 75 Q02750,O95155,Q15555,P41227,Q15645,Q15813,Q15392,Q6DKJ4,Q15056,Q06124,Q4J6C6,Q9UBM7,Q96J02,O96028,P07437,Q01968,O43924 17 +Vitiligo 0.4415654252233876 0.8199218823472625 0.4122606413404566 1.0 0.842038351228631 8 P03886 1 +Gastrostomy tube feeding in infancy 0.2979543368518184 0.8184046755668316 0.4131261528354439 1.0 0.842038351228631 34 Q01105,P30153,Q99720,Q9UP83,Q9H490,Q96J02,Q05639 7 +Pallor 0.280858859788726 0.8178149353984888 0.4134628685047294 1.0 0.842038351228631 49 Q9NVI1,P00374,P62899,P62081,P08708 5 +Dermatological manifestations of systemic disorders 0.2682222930773365 0.8177442610457054 0.4135032313486784 1.0 0.842038351228631 75 O43772 1 +Abnormality of neutrophil physiology 0.5670856474715262 0.8102592248537783 0.417791205064657 1.0 0.8425597536708528 4 Q7Z2Z2,P06744,P61011 3 +Metaphyseal chondrodysplasia 0.5670856474715243 0.8102592248537698 0.4177912050646619 1.0 0.8425597536708528 4 Q7Z2Z2,P61011,O95831 3 +Anterior rib cupping 0.567085647471522 0.8102592248537598 0.4177912050646677 1.0 0.8425597536708528 4 P61011,O15357,O95831 3 +Abnormality of vitamin e metabolism 0.5670856474715141 0.8102592248537288 0.4177912050646855 1.0 0.8425597536708528 4 Q7Z2Z2,P61011,Q13043 3 +Proximal femoral epiphysiolysis 0.5670856474715077 0.8102592248537025 0.4177912050647006 1.0 0.8425597536708528 4 Q7Z2Z2,Q96DX4,P61011 3 +Hypoamylasemia 0.5670856474715014 0.8102592248536766 0.4177912050647154 1.0 0.8425597536708528 4 Q7Z2Z2,P61011,A5YKK6 3 +Abnormal circulating amylase level 0.5670856474715014 0.8102592248536766 0.4177912050647154 1.0 0.8425597536708528 4 Q7Z2Z2,P61011,A5YKK6 3 +Lower limb metaphyseal irregularity 0.5670856474714993 0.8102592248536685 0.4177912050647201 1.0 0.8425597536708528 4 Q96DX4,P61011,P26373 3 +Alkalosis 0.5375042262278084 0.8071829583579415 0.419561082491755 1.0 0.8437257508284162 5 P04150,P40818 2 +Abnormality of the diaphragm 0.330291568676313 0.8042390724328932 0.4212589173938119 1.0 0.8441942060697772 26 Q9UBM7,P38935,O96028 3 +Retinal dysplasia 0.4382362246820422 0.8031167587253388 0.4219072521594094 1.0 0.8441942060697772 8 O43505,O43924 2 +Retinal vascular tortuosity 0.3620018400012582 0.8021684365783606 0.4224555317322425 1.0 0.8441942060697772 17 O75306,P03886 2 +Dystrophic fingernails 0.4156529727972536 0.7976569826835253 0.4250695736301528 1.0 0.8446965150755407 10 P18074,Q02750,P26639,Q9H4A3,P36507 5 +Abnormal glial cell morphology 0.2636843948112102 0.7966654646022558 0.4256453462400422 1.0 0.8451192887392908 66 P48735,O75874,P42771,Q9H9P8,O75306,O95831,P42858 7 +Abnormal t wave 0.5625626800200956 0.791995929597119 0.4283630496252795 1.0 0.8458262761048776 4 P0DP25 1 +Hypotelorism 0.2946570060105243 0.7901628274751257 0.4294326819671852 1.0 0.8467148534036995 34 P18074,A5YKK6,P48444,Q9BXW9,P26639,Q93008,Q9Y3C4,Q9UHD8,Q9NPF4,Q7Z6Z7,Q15042,O14617,O43776 13 +Ocular albinism 0.4943177276838805 0.7891754653297065 0.4300094596184403 1.0 0.8467148534036995 6 O00203,O14617,O95155 3 +Psychotic mentation 0.4643830934535202 0.7881492884002768 0.4306093877786896 1.0 0.8467148534036995 7 P03886,P40818 2 +Abnormal patella morphology 0.32210581423681 0.7797057611410203 0.435564086997124 1.0 0.847664141254989 27 Q96AY3,Q15056,Q15125,Q01968,Q96PU5 5 +Female infertility 0.5591615802374272 0.77831771581919 0.4363817340473921 1.0 0.847664141254989 4 Q15645 1 +Rib fusion 0.418584751015236 0.7724932714912787 0.439822330502543 1.0 0.8487480006767905 9 O95155,O96028 2 +Stomach cancer 0.3944868366748735 0.7685820718373821 0.4421414518408788 1.0 0.8494131799087913 12 P42771,Q15645 2 +Thin skin 0.3200585262609469 0.7645562165425562 0.4445358493239162 1.0 0.8500036609659769 27 Q9H4L7,Q13126 2 +Supranuclear gaze palsy 0.3523888458802834 0.7578193290477327 0.4485591493243113 1.0 0.8532935211242815 18 Q99720 1 +Conjugated hyperbilirubinemia 0.5536942154883241 0.7564343628570196 0.449388811906044 1.0 0.8532935211242815 4 Q9Y5L0,Q9H267 2 +Bilateral polymicrogyria 0.4152379799000113 0.7552000845595693 0.4501289379386493 1.0 0.8532935211242815 9 Q01105,P42356 2 +Thyroiditis 0.4284038858400292 0.7538307773589094 0.4509508406597522 1.0 0.8536598066104553 8 P50851,Q15437,Q96J02 3 +Ulnar deviation of finger 0.4278489531037334 0.7510657548298032 0.4526130839927866 1.0 0.8540179693754122 8 Q9UBM7 1 +Mesomelia 0.4273874259326845 0.7487675765575095 0.4539973053739263 1.0 0.855777319817168 8 Q9UBM7 1 +Juvenile myelomonocytic leukemia 0.551515223793384 0.7477505019111836 0.4546106632800064 1.0 0.855777319817168 4 Q02750 1 +Myeloid leukemia 0.551515223793384 0.7477505019111836 0.4546106632800064 1.0 0.855777319817168 4 Q02750 1 +Increased circulating acth level 0.4848965131588489 0.7474388139029267 0.4547987235456268 1.0 0.855777319817168 6 P04150,O00170,P40818 3 +Cutis marmorata 0.3448681243707017 0.7455296786319638 0.4559515764041881 1.0 0.855777319817168 20 Q9UBM7 1 +Abnormality of the adrenal glands 0.2635230335084915 0.743900308166679 0.456936788938697 1.0 0.8557915081651543 62 P48735,O75874 2 +Severe demyelination of the white matter 0.6644814518971124 0.7428448904349505 0.4575755938711079 1.0 0.8559549879726309 3 Q9H9P8 1 +Large intestinal polyposis 0.405088272047082 0.7420643605198197 0.4580483417722738 1.0 0.8564952125669506 10 P42771,Q15437,Q9UPY3 3 +Central nervous system cyst 0.2666810456995562 0.7370343557618733 0.4611014570540157 1.0 0.8574193013716527 58 O43505,Q9Y285,Q15645,Q96HP0,Q9UID3,Q15125,Q9UBM7,O96028 8 +Abnormal muscle fiber type distribution 0.3886329467053394 0.7368032649468951 0.4612419974202275 1.0 0.8574193013716527 12 Q9Y5P6,P50570,P51114,Q06210,Q9Y281,P06753,Q8NCE2,Q14204 8 +Abnormal motor nerve conduction velocity 0.3252952855260124 0.7356736265079695 0.4619293435501546 1.0 0.8578951031390187 25 P04792,Q99720 2 +Focal non motor seizure 0.4036838484068468 0.7347307556455391 0.4625034855942975 1.0 0.8582510786782082 10 Q01105,P42356 2 +Cns demyelination 0.3623268790333523 0.7336740197858206 0.4631474362562453 1.0 0.858445248092786 15 P49770,Q14232,Q9NR50,Q13144,Q9H9P8,P60891 6 +Neoplasm of the male external genitalia 0.4031827218345679 0.7321174294947771 0.4640968963742822 1.0 0.8597071665548229 10 P42771,Q01844 2 +Tics 0.4522976190907067 0.7314586233556037 0.4644990688731034 1.0 0.8599235247209422 7 Q96RL7 1 +Chylothorax 0.5188602739427448 0.7296107757017586 0.4656281336272441 1.0 0.8606286068655077 5 Q02750 1 +Decreased circulating iga level 0.4225289513160754 0.7246566425798919 0.468662700344274 1.0 0.8642226115311739 8 Q96J02,P13051 2 +Abnormality of the clitoris 0.3319504106219857 0.724256689333823 0.4689081612200874 1.0 0.8642226115311739 23 Q13535,Q9UBM7 2 +Gastrointestinal inflammation 0.3318714243578307 0.7237255074639267 0.469234270178438 1.0 0.8642226115311739 23 P50851,Q9Y5L0,Q7Z392,Q6PGP7,O95999,P98170,P42224,Q13043,Q15477,Q13546 10 +Iris hypopigmentation 0.4083274596877394 0.7197234809274137 0.4716952659957378 1.0 0.866776576545718 9 O00203,O14617,O95155 3 +Abnormal b cell subset distribution 0.5438564612223812 0.7174091353356482 0.4731216844650125 1.0 0.8679593785788499 4 P50851 1 +Gray matter heterotopia 0.2832050941782624 0.7154850227573443 0.4743093922600385 1.0 0.8691263155003374 37 P46821,O43505,Q00534,Q9BVA1,P42695,O43379,P43034,Q9UBM7,Q96PU5 9 +Neoplasm of the rectum 0.359188907814256 0.7151601097244352 0.4745101146911206 1.0 0.8691263155003374 15 P42771,Q15437,P54277,Q9UPY3 4 +Myelodysplasia 0.271016921453965 0.7107075425563981 0.4772654847120914 1.0 0.8697252825125235 46 Q9NVI1,P62081,P62899,Q9BXW9,P62847,Q15645,P39019,P42771,Q06124,O76094,P08708 11 +Abnormality of the pylorus 0.2814305136569823 0.7088933885316879 0.4783906382290204 1.0 0.8708655330206613 38 O95155,P46109,Q9UBM7,Q8NCE2,Q96PU5 5 +Patellar dislocation 0.3418569686865961 0.7081748948237432 0.4788366544271127 1.0 0.8708655330206613 19 Q01968,Q15125,Q96PU5,Q15056 4 +Abnormal platelet aggregation 0.541054923860677 0.706384254736967 0.4799492098236375 1.0 0.8712306254004983 4 O00203 1 +Preaxial hand polydactyly 0.3902751703464313 0.7044049294750532 0.481180637008789 1.0 0.8712306254004983 11 O96028 1 +Absent hand 0.6535450826977038 0.7037784949955069 0.48157072809125 1.0 0.8712306254004983 3 Q96HP0 1 +Talipes valgus 0.4747282663292795 0.7029119079027726 0.4821106497271876 1.0 0.8712306254004983 6 P49589,Q9HD42 2 +Spontaneous abortion 0.6528345996493162 0.7012599458573834 0.4831408054368284 1.0 0.8712878592685505 3 Q9NQX3,Q8NCE2 2 +Gastritis 0.4736159520941727 0.6980769800516975 0.4851290534554113 1.0 0.8721084451306546 6 P50851,Q13546,Q6PGP7,Q15477 4 +Profound hearing impairment 0.4721937454750441 0.6919059399136197 0.4889964001602911 1.0 0.8770289827220012 6 P54577,P60891 2 +Autoimmune hemolytic anemia 0.4017861216300745 0.6864569574794459 0.4924249978649531 1.0 0.880352665715382 9 P50851,P49327,P00491,Q969U7,P42224 5 +Undetectable visual evoked potentials 0.6482018283236899 0.6848984975948326 0.493407974135327 1.0 0.880352665715382 3 P60891 1 +Psychotic episodes 0.6481589713617866 0.6847476423852252 0.4935031796462799 1.0 0.880352665715382 3 Q99497,P08397 2 +Neoplasm of the stomach 0.3287454586460253 0.680871182113128 0.4959530041788933 1.0 0.8830429015131653 22 Q15645,Q9NYB0,Q6PD74,P42771,Q9Y620 5 +Aplasia hypoplasia of the thumb 0.2674118623191199 0.6797581768112202 0.4966575925087415 1.0 0.8838235527402654 47 Q9NVI1,P62081,P62899,Q9UBM7,O96028,P08708 6 +Abnormality of the thyroid gland 0.2523467830604512 0.6770064680756819 0.4984018505368541 1.0 0.8853291234158877 109 P48735,Q9NVI1,O95155,O75874,Q9Y285,Q15437,Q15645,Q15056,P42771,Q9UPY3,Q96J02,P03886 12 +Abnormal mitochondria in muscle tissue 0.3310556916197032 0.6757578447032206 0.4991944033325912 1.0 0.8854243478751579 21 Q9NPL8,P03886 2 +Heat intolerance 0.4678696276951462 0.6732207664312281 0.5008068516562543 1.0 0.8855893282611166 6 P36507,Q02750,P00338 3 +Shoulder dislocation 0.5041505696621027 0.6696437014212406 0.5030849484772273 1.0 0.8883081029282763 5 Q96PU5 1 +Choriocarcinoma 0.5314931296463045 0.6690767919891332 0.5034464935184746 1.0 0.8883081029282763 4 P42771 1 +Dilatation of the ventricular cavity 0.6432953549518041 0.6672339454123356 0.5046227115102297 1.0 0.8894528414966536 2 P27635 1 +Nemaline bodies 0.5299124214917552 0.6629596188361496 0.5073564167563396 1.0 0.890485805835145 4 P07196,P06753 2 +Acute myeloid leukemia 0.2801507519661727 0.6628329549073927 0.5074375449265331 1.0 0.890485805835145 33 P42771,P08708,P62081,P62899 4 +Cerebellar cortical atrophy 0.6415425065731867 0.6607587157098881 0.508767062457075 1.0 0.8906044073281706 2 Q9Y263 1 +Hyperuricosuria 0.6408533021624877 0.6591711643997689 0.5097858614744473 1.0 0.8906044073281706 3 Q08426,P60891 2 +Uric acid nephrolithiasis 0.6408533021624807 0.6591711643997453 0.5097858614744624 1.0 0.8906044073281706 3 P07741,P60891 2 +Macroscopic hematuria 0.6406660823838802 0.6575285200708656 0.5108411388686545 1.0 0.8906044073281706 2 P07741 1 +Fine hair 0.3403296130300491 0.6552306617306827 0.5123192558549607 1.0 0.8906044073281706 16 P04080,Q02750,Q6PGP7,P49589,P41227,P36507,A2RRP1,Q01968 8 +Aplasia of the uterus 0.4083480213205761 0.6552303756873619 0.5123194399934994 1.0 0.8906044073281706 8 O96028 1 +Axonal degeneration 0.43556359136509 0.6544361440485365 0.5128308545305715 1.0 0.8906044073281706 7 Q6DKK2 1 +Fetal ultrasound soft marker 0.3355527619940254 0.6531889690346527 0.5136344608240195 1.0 0.8906044073281706 18 Q15125 1 +Renal phosphate wasting 0.6388077147866704 0.6520607423554304 0.514361988022372 1.0 0.8906044073281706 3 Q08426,O15357 2 +Elevated circulating long chain fatty acid concentration 0.6384824912799524 0.6509323847268015 0.5150901351740056 1.0 0.8906044073281706 3 P40855 1 +Positional foot deformity 0.2500081675960225 0.6463939332809918 0.5180242683402227 1.0 0.8906044073281706 109 Q13614,Q96AY3,P42356,Q96HP0,Q15392,P04792,Q13535,Q15125,Q9UBM7,O96028,Q8TD16,Q9HD42 12 +Distal lower limb amyotrophy 0.354638709833367 0.6405598460464971 0.521808694955548 1.0 0.8906044073281706 14 P04792,P07196,P06753,Q27J81,Q8TD16 5 +Abnormal morphology of the limbic system 0.3622508582991652 0.6381182785558982 0.5233966888681312 1.0 0.8906044073281706 13 Q9UID3,Q01105 2 +Cutaneous abscess 0.5232452947626444 0.6373257910261779 0.5239126547821824 1.0 0.8906044073281706 4 O95394,Q13546 2 +Action tremor 0.2568257271340683 0.636202286099122 0.5246445833123059 1.0 0.8906044073281706 58 Q2TAL8,P03886,Q99720 3 +Optic neuropathy 0.3185628690314661 0.6355470383094574 0.5250716985321842 1.0 0.8906044073281706 23 Q9NPL8,P03886 2 +Inflammation of the large intestine 0.3454267002855135 0.6352189602673818 0.5252856190170718 1.0 0.8906044073281706 15 P50851,O95999,P98170,Q13043,Q15477 5 +Abnormal circulating phenylalanine concentration 0.6339120794853015 0.6351379489774771 0.5253384486011907 1.0 0.8906044073281706 3 P35270 1 +Abnormality of the 5th toe 0.3769213795816349 0.6349685159825188 0.5254489490830079 1.0 0.8906044073281706 11 Q9UBM7 1 +Postaxial foot polydactyly 0.3769213795816349 0.6349685159825188 0.5254489490830079 1.0 0.8906044073281706 11 Q9UBM7 1 +Cold induced muscle cramps 0.6318658446023285 0.6281051489162145 0.5299350603070272 1.0 0.8938460625345593 3 P23786 1 +Hemiparesis 0.323502211712964 0.6276905625031514 0.5302066689486622 1.0 0.8938460625345593 21 Q96HP0,P03886 2 +Proportionate tall stature 0.632486123283679 0.6276259784105706 0.5302489863902013 1.0 0.8938460625345593 2 O00170 1 +Abnormal spinal meningeal morphology 0.6324861232836728 0.6276259784105489 0.5302489863902156 1.0 0.8938460625345593 2 P31153 1 +Barrel shaped chest 0.5198114910185831 0.6242332910780823 0.5324743865190353 1.0 0.8966367969738259 4 Q32P28,Q14739 2 +Multiple cafe au lait spots 0.3433774577234553 0.623510235389426 0.532949278271817 1.0 0.8966500655060887 15 Q9NVI1,Q02750,Q9BXW9,Q15437,Q15645,P36507 6 +Adrenal hyperplasia 0.4285956929713098 0.622960705349987 0.533310344302868 1.0 0.8966500655060887 7 P04150,P40818 2 +Abnormal cortical bone morphology 0.319769226013965 0.6228935257209274 0.5333544928321294 1.0 0.8966500655060887 22 P35606,Q00534,P40855,Q9H4A3,Q15813,P42695,O43379,Q9NSD9,Q6UVJ0,A1X283 10 +Frontal lobe dementia 0.6307332749050663 0.6212778629002564 0.5344168164091812 1.0 0.8969405646167806 2 Q99497 1 +Broad neck 0.3667507734010613 0.6207352355513337 0.5347738417904173 1.0 0.8969405646167806 12 Q07864,Q15555,P78318 3 +Abnormal eyelid physiology 0.4277141315280022 0.619006291680472 0.5359122140865329 1.0 0.8982027605424396 7 Q9NQZ5,Q99497,Q96RL7 3 +Squamous cell carcinoma 0.3318287110377912 0.6170475424180252 0.5372033676468635 1.0 0.8990722069603869 17 P42771,Q9H4L7 2 +Recurrent fever 0.3317769286413667 0.6167395707862887 0.5374065161976707 1.0 0.8990890188344789 17 P28070 1 +Abnormal paranasal sinus morphology 0.3079716899388694 0.6164424878715626 0.5376025187478675 1.0 0.8990938675610887 25 P50851,P28070,Q86Y56 3 +Keratoconjunctivitis 0.380383311626248 0.6154202255522602 0.5382772377510228 1.0 0.89925325402539 10 P18074,P49327,Q14739,P26639,P50747 5 +Immune dysregulation 0.6286882851300093 0.6138991854848878 0.5392819484780704 1.0 0.8996405417821197 2 P42224 1 +Congenital contracture 0.26038201889675 0.6120646321158142 0.5404949964845569 1.0 0.9002637640182706 46 Q15392,Q96AY3,P42356,Q9HD42 4 +Intestinal malrotation 0.2796794660998819 0.6118722061279549 0.5406223118975697 1.0 0.9002637640182706 31 Q9UBM7,O96028 2 +Abnormal blood monovalent inorganic cation concentration 0.3236034846284 0.6109724608455523 0.5412178120799176 1.0 0.9003569197551663 20 P08397,Q9UNF1,Q08426,Q9H4A3,P40818,P04150,Q01968,P0DP25 8 +Antinuclear antibody positivity 0.4530944025220386 0.6103336883552053 0.5416407851017206 1.0 0.9006712483691469 6 Q9Y5L0,P51617,Q13546,P53621 4 +Capillary hemangioma 0.398596729590632 0.6084371847082265 0.5428975554984039 1.0 0.9018920147832918 8 Q9UBM7 1 +Clubbing of fingers 0.488441764817464 0.6070642922927592 0.5438082460532259 1.0 0.9018920147832918 5 Q86TI2 1 +Abnormal auditory evoked potentials 0.3699963449376511 0.5996705415739669 0.5487258245054627 1.0 0.9056606903100898 11 Q13614,Q15125 2 +Cupped ear 0.3470299548765775 0.5986213577162748 0.5494254103756773 1.0 0.9059062752869804 14 Q2TAL8,Q15392 2 +Decreased methylcobalamin 0.6234297399941665 0.5950645713723932 0.5518003095190314 1.0 0.9078382477457988 2 P11586 1 +Lower limb amyotrophy 0.3207490347787959 0.5934263325405792 0.5528958704832754 1.0 0.9086774348641476 20 O00400,Q9Y223,P04792,P07196,P06753,Q27J81,Q8TD16 7 +Abnormality of corneal size 0.2638885425969918 0.5858200885847089 0.5579964226033503 1.0 0.9108525774663406 41 O43505,O15347,Q15555,P41227,Q15056,Q96EK5,Q15125,O96028,P07437,A1X283 10 +Duplication of hand bones 0.2491590375130209 0.583750645270841 0.5593880880707145 1.0 0.9108525774663406 61 P62081,P62899,P62847,Q9UPP1,Q15125,Q9UBM7,O96028,P08708,O43924 9 +Abnormality of dna repair 0.4821934029455025 0.5826518557543026 0.5601276893122782 1.0 0.9108525774663406 5 P18074,Q9BXW9 2 +Prenatal movement abnormality 0.2449020549853998 0.579034816158645 0.5625656811806652 1.0 0.9108525774663406 65 Q9GZZ9,Q8NCE2,O43379,Q4J6C6,Q9UBM7,P38935,O96028,Q8TD16 8 +Abnormality iris morphology 0.250057479052335 0.5776962960953531 0.5634691802605585 1.0 0.9108525774663406 86 Q9NVI1,O43505,Q9UBC2,O95155,Q15645,Q15056,O00203,Q96EK5,Q9UBM7,O96028,Q96IJ6,Q01968,P78318 13 +Skin appendage neoplasm 0.4807590992880977 0.5770897305549004 0.5638788412969142 1.0 0.9108525774663406 5 Q15437 1 +Abnormality of the pulmonary vasculature 0.2559658162035266 0.5742724487488932 0.565783450013331 1.0 0.9112029551235106 47 P41227,P27635,Q96HP0,Q9NXH9,Q15392,Q15056,Q86Y56,Q96PZ0,Q06124,Q9Y296,Q7Z6Z7,Q15477,P42858 13 +Abnormal pupil morphology 0.3340489684602449 0.5709403045044977 0.5680401088287956 1.0 0.9116838147903732 15 O96028,Q96IJ6 2 +Abnormal hemoglobin 0.3047712311740183 0.5699785875751902 0.5686922211289898 1.0 0.9120875154151756 24 P62081,P62899,P62847,P39019,P08708 5 +Vitritis 0.613923417329939 0.5675311466839974 0.5703533715275209 1.0 0.9125653944440334 3 P04439 1 +Large for gestational age 0.3703904510532794 0.5658785388030474 0.5714763516270667 1.0 0.9128435702213628 10 Q12955,Q8NCE2,P31751 3 +Long toe 0.3632537403932769 0.5658326945106112 0.5715075187275069 1.0 0.9128435702213628 11 Q9UPP1 1 +Increased bone mineral density 0.3002692880530676 0.5652375396868279 0.5719122062551834 1.0 0.9128727549032778 25 Q15813,Q15392,Q13126,Q15056,Q15125 5 +Toe walking 0.3036457830040472 0.5627342573819799 0.5736158532003179 1.0 0.9128727549032778 24 Q8TD16,Q99720 2 +Iron accumulation in brain 0.6124317604185923 0.5625887827183661 0.5737149321091826 1.0 0.9128727549032778 3 Q96RL7 1 +Abnormal delivery 0.3033646409839688 0.5609288929116237 0.5748460125198085 1.0 0.9137873111274252 24 Q8NCE2,Q9UBM7,P06753 3 +Abnormal cranial nerve physiology 0.247182397392098 0.559129014552481 0.5760736743688368 1.0 0.9141900393389796 80 P48735,Q13614,P42356,O95155,O75874,O95817,Q8NCE2 7 +Bilateral cryptorchidism 0.3611931588429954 0.5556037259547981 0.5784817837720717 1.0 0.9167498928668366 11 Q07864,O43924,P78318 3 +Motor neuron atrophy 0.3024326181436211 0.554956326693459 0.5789245331545787 1.0 0.9171393761033408 24 P07737,Q99720 2 +Bicornuate uterus 0.3746531373507631 0.5525135400062208 0.5805965603158469 1.0 0.918538085229556 9 Q9UBM7 1 +Abnormality of the gallbladder 0.2606549399154093 0.5498459106200528 0.5824250660668393 1.0 0.9195561572082752 40 P06744,Q9UN37,P53004,Q15437,Q15056,Q9Y223,Q9UBM7,O96028 8 +Lower limb asymmetry 0.3853136762945348 0.5461695097405534 0.5849494228219925 1.0 0.9204205855556598 8 P07437,Q93008,Q15555,O95155 4 +Hypochromia 0.6082383873795039 0.5418473067932529 0.5879236990924737 1.0 0.9211927437579503 2 P11172 1 +Subarachnoid hemorrhage 0.607654104586624 0.5398378367040066 0.5893088709748457 1.0 0.9211927437579503 2 P31153 1 +Low levels of vitamin d 0.3719745464917623 0.5397098276054536 0.5893971614379154 1.0 0.9211927437579503 9 Q7Z2Z2,P46783,P61011,Q9NSD9,Q13043,Q01968 6 +Renal agenesis 0.2469633737358345 0.5389823350593604 0.5898990435657785 1.0 0.9213585866629536 58 Q00534,P62899,P62081,P30153,P62847,Q15392,P42695,O43379,Q9UBM7,P08708,O75306,O43924 12 +Increased hepatic glycogen content 0.4959421555034985 0.5355338856237515 0.5922807324408024 1.0 0.9229136357900805 4 P06737,P31751 2 +Abnormality of vitamin d metabolism 0.3641478162116268 0.5355234272929261 0.5922879622456616 1.0 0.9229136357900805 10 Q7Z2Z2,P46783,P61011,Q9NSD9,Q13043,Q01968 6 +Mild global developmental delay 0.3196959476381221 0.5352450407593436 0.5924804246942763 1.0 0.9229136357900805 16 Q01968,P46821,Q13535,O00203 4 +Abnormal cd4 cd8 ratio 0.4694557526599843 0.5338369148442448 0.5934543713373726 1.0 0.9236469434680928 5 O00203 1 +Cone cone rod dystrophy 0.605901256208013 0.5338267472445519 0.593461406540748 1.0 0.9236469434680928 2 Q6P4Q7 1 +Increased circulating antibody level 0.3131654219078826 0.5331726496554638 0.5939140723972067 1.0 0.9236469434680928 19 P28070,P98170 2 +Toe syndactyly 0.2393608546938608 0.5321676180963166 0.5946099084690171 1.0 0.9236469434680928 66 Q9NVI1,Q9H4L7,P46109,Q6DKJ4,Q15125,Q9UBM7,O43924,Q96PU5 8 +Telangiectasia 0.2592459665529076 0.5305370682399334 0.5957396153533685 1.0 0.923735444981693 39 O95155,Q15437,Q13535,O75306,P03886 5 +Abnormal platelet morphology 0.4674726070512344 0.5263597586755588 0.5986382698275334 1.0 0.9250779237693314 5 O00203 1 +Lymphoma 0.2819870773314296 0.5249669535680139 0.5996061639100763 1.0 0.9256855309140016 28 P50851,Q07864,O95999,P98170,Q6PD74,P42771,Q9Y620 7 +Buphthalmos 0.4929598051913306 0.5247633606876496 0.5997477048841857 1.0 0.9256855309140016 4 Q01968 1 +Uveitis 0.3614456801683404 0.5225378813715021 0.6012958783494147 1.0 0.9256855309140016 10 P50851,Q13043,O95999 3 +Giant platelets 0.6009348524686033 0.5169388918076979 0.6051988172951859 1.0 0.9268170768971736 2 Q14739 1 +Abnormal neuron morphology 0.2668854154680807 0.5156003141136067 0.6061335908831387 1.0 0.9268170768971736 31 P07737,Q99720 2 +Aplasia hypoplasia of toe 0.2595918412358602 0.5144410644546332 0.6069436552259742 1.0 0.9274465568533428 36 O96028,Q9UBM7,Q96HP0 3 +Neutropenia in presence of anti neutropil antibodies 0.3776093149450361 0.5109410835898663 0.6093923122080791 1.0 0.9290538983761676 8 P49327,P00491,O95394,P29144,P42224,Q96J02 6 +Ankyloglossia 0.3762173899658848 0.5046524946181337 0.6138029325721757 1.0 0.9318917881456612 8 Q6DKJ4,P46109 2 +Sensory ataxia 0.4870941294122817 0.5038025002733467 0.614400170537936 1.0 0.9318917881456612 4 P06744 1 +Encephalocele 0.3140532602009155 0.5036519052673402 0.6145060109331018 1.0 0.9318917881456612 16 Q15051,Q96HP0 2 +Unilateral renal agenesis 0.2939495560194282 0.5015212981609012 0.6160042924942586 1.0 0.9319555945439484 24 Q00534,P30153,P42695,O43379,Q06124,Q9UBM7 6 +Intellectual disability progressive 0.3195012659599198 0.4916821497651801 0.6229440590362343 1.0 0.9353454780420136 15 Q9H9P8,O95721 2 +Proximal tubulopathy 0.2955182234547518 0.4906080650514478 0.6237036810820313 1.0 0.93538038367733 23 Q9NPL8,P03886 2 +Hypothalamic hamartoma 0.5900058445353514 0.490205176524336 0.6239887181490091 1.0 0.93538038367733 3 O43924,Q9H269 2 +Clonus 0.2571582980346974 0.4867145154635467 0.6264606572016078 1.0 0.9368767551815648 34 Q8N0X7,Q99720 2 +Non hodgkin lymphoma 0.3468777627563612 0.4861422956189543 0.6268662807875427 1.0 0.9368927317533424 11 P42771,O95999,P98170 3 +Single transverse palmar crease 0.2451822495628022 0.4857944261612598 0.6271129265895368 1.0 0.9368927317533424 50 Q9H4L7,Q96HP0,Q6DKJ4,Q9UID3,Q13535,Q96J02,O96028 7 +Sloping forehead 0.2434608229045314 0.4844128062093245 0.628092931708641 1.0 0.9376084289950088 54 Q9NVI1,Q00534,Q15645,Q13535,Q96EK5,P35606,A5YKK6,O60566,P26640,Q15003,O43379,Q9BXW9,Q9H267,Q9BSJ2,Q9UPP1,P42695,Q9H9E3,Q13409,Q6UVJ0,Q9NPF4,P08243,Q16851 22 +Autoamputation of digits 0.5878905573819082 0.4835754069985393 0.6286872317954808 1.0 0.9378556753792892 3 Q9H4A3 1 +Acral ulceration 0.5878905573819082 0.4835754069985393 0.6286872317954808 1.0 0.9378556753792892 3 Q9H4A3 1 +Dolichocephaly 0.2555610570960655 0.4833280202372537 0.628862847623312 1.0 0.9378556753792892 36 Q9NVI1,P42356,P48444,O95721,Q9BXW9,P27635,Q14738,Q4J6C6,Q96J02,O96028,P60891 11 +Renal hypoplasia 0.2616867159719672 0.4779689172546623 0.632672328240798 1.0 0.940911301778662 31 Q9NVI1,P41227,Q15056,Q9UBM7,O43924 5 +Aplasia hypoplasia of the extremities 0.2426471899624451 0.4765411536276945 0.6336888957042113 1.0 0.9414344283340164 196 P48735,Q9NVI1,Q9UBC2,O95155,O75874,Q9NXH9,Q9UBM7,Q14320,Q96AY3,P62847,Q15813,Q96HP0,Q13535,Q15125,Q96EK5,O96028,P42858,P62899,P46109,Q6DKJ4,O95831,P62081,Q15555,Q15392,P08708,Q8N0X7 26 +Chronic mucocutaneous candidiasis 0.3696368196665742 0.4752567389733189 0.6346039899513429 1.0 0.942192658550208 8 O95394,O14920,Q03426,P42224,O00203 5 +Joint contracture of the hand 0.2412780738133072 0.4739148879414817 0.6355606021170703 1.0 0.9424108800818723 56 Q9H4L7,O95155,P46109,P41227,Q15392,Q6DKJ4,Q9UP83,Q9NPF4,P38935,P07196,P06753,Q01968,A1X283 13 +Infectious encephalitis 0.337092022050786 0.4726099938140151 0.6364914511528919 1.0 0.9425285001792192 12 Q9H9P8,P98170 2 +Primitive neuroectodermal tumor 0.2978651522573711 0.4723140860797603 0.636702617490343 1.0 0.9425285001792192 21 O95155,Q15555,P54277,P42771,Q06124,Q9UPY3 6 +Postaxial polydactyly 0.2853463044599281 0.4699995475626645 0.6383553408092946 1.0 0.9426522254386538 25 Q9UBM7 1 +Recurrent otitis media 0.2773524744874662 0.4667707508457522 0.6406639044224398 1.0 0.94420586312919 27 P50851,O00203,Q9UBM7,P41227 4 +Oral ulcer 0.356046648550386 0.4654657383801063 0.6415979669245726 1.0 0.9443384502658156 9 Q7Z2Z2,P49327,P61011,Q9Y3A5,Q03426,P51617,Q13546 7 +Aplasia hypoplasia of the cerebellum 0.2172223557619141 0.4648297416563819 0.6420533872734133 1.0 0.9443384502658156 150 P00374,P42356,Q96HP0,Q9UID3,Q15125,Q13535,Q9UBM7,O96028,Q9H9P8,Q15051,Q8TD16,Q9HD42 12 +Vertebral segmentation defect 0.259307381701804 0.4610673516341495 0.6447502844146211 1.0 0.9463925990650932 31 Q9NVI1,Q15125,O96028,Q15056 4 +Megalocornea 0.3275654332549174 0.4595146518178653 0.6458646328795503 1.0 0.9469539492830764 13 O96028,Q15056 2 +Periventricular nodular heterotopia 0.4742695421152606 0.4590664386061246 0.6461864565462352 1.0 0.9469539492830764 4 Q96PU5 1 +Ulnar deviation of the hand or of fingers of the hand 0.3340557019221586 0.4582020659335661 0.6468072757758205 1.0 0.9471774291164704 12 Q9UBM7 1 +Esophagitis 0.3902867173785848 0.4580557073915136 0.6469124193707851 1.0 0.9471774291164704 7 Q7Z392,O95394,P62913,P41252,Q9NQX3,O43175 6 +Abnormal shape of the palpebral fissure 0.3333543558824589 0.4548967868100045 0.6491834946650328 1.0 0.9489690526049996 12 O14646 1 +Abnormal breath sound 0.3332389119203691 0.4543535565037915 0.6495743744201172 1.0 0.9489690526049996 12 Q86TI2,P38935,Q969Y2 3 +Acne 0.3013858755483526 0.4541645273104322 0.6497104124492938 1.0 0.9489690526049996 18 P98170,P40818,O00170,P04150,A1X283 5 +Dry skin 0.2583072208362306 0.4540258224991141 0.6498102411224442 1.0 0.9489690526049996 31 P04080,Q02750,Q9H4L7,Q9NYB0,Q9Y3Z3,P42771,Q15477 7 +Anteverted ears 0.5778706560930266 0.4526709613402515 0.6507856926477156 1.0 0.9489690526049996 3 O15347 1 +Hemimegalencephaly 0.577147866744586 0.4504744786109727 0.6523683524457797 1.0 0.950155752775844 3 P42345,Q9Y243 2 +Demyelinating peripheral neuropathy 0.2986331677489799 0.4502957510934788 0.6524972022822384 1.0 0.950155752775844 19 P07196,P03886,O95817 3 +Vertebral fusion 0.3389473234084924 0.4489937693731493 0.6534361512861366 1.0 0.950155752775844 11 O96028 1 +Aplasia hypoplasia of the hallux 0.2911365631988102 0.4483942267082713 0.6538687076430245 1.0 0.950159150873094 22 Q9NXH9,O00232,Q96PZ0,Q9Y296,O96028,Q7Z6Z7,P42858 7 +Receptive language delay 0.2958986426547619 0.4473993064225189 0.6545867765080657 1.0 0.9506413073679209 20 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,Q16512,P42858 7 +Polydactyly 0.2393873041156987 0.4443398930048061 0.6567968630830054 1.0 0.9526623658923592 53 Q9UPP1,Q15125,Q9UBM7,O96028 4 +Pancreatic adenocarcinoma 0.3308370051285501 0.4431050601774716 0.6576897452815329 1.0 0.9528393494981684 12 Q16658,P52701,P54277,Q6PD74,P42771,Q5HYI8 6 +Pseudobulbar paralysis 0.3616803074414985 0.4404974099387336 0.6595768877770232 1.0 0.9534590308413656 8 P42356,P08397 2 +Muscle fibrillation 0.3005469185724205 0.4394817295807026 0.6603125177015572 1.0 0.9541946252074645 17 P51114,P04792,Q8NCE2 3 +Erythema 0.2835788566443556 0.4386997793412603 0.6608790869927608 1.0 0.9542216349490926 24 P03886 1 +Focal cortical dysplasia type ii 0.5769792579608658 0.4386774518267264 0.6608952674561384 1.0 0.9542216349490926 2 P42345 1 +Delusions 0.294184862108805 0.4378411750560198 0.6615014205805125 1.0 0.9544315507353164 20 P49770,P08397,Q14232,Q9NR50,Q96RL7,P42858 6 +Shield chest 0.4416545546418166 0.4324398941179889 0.6654217283200756 1.0 0.9552454523467628 5 Q06124,Q02750 2 +Aplasia of the fingers 0.2680422715057118 0.4323946712154393 0.6654545904177143 1.0 0.9552454523467628 28 Q9NVI1,P62081,P62899,P46783,Q9BXW9,P62847,P39019,P08708 8 +Hip contracture 0.3285182758509712 0.4323453350899356 0.6654904422013663 1.0 0.9552454523467628 12 Q96AY3 1 +Hypoplastic anemia 0.5749342681858165 0.4322588137452859 0.6655533177433111 1.0 0.9552454523467628 2 P39019 1 +Molluscum contagiosum 0.5749342681858124 0.4322588137452734 0.6655533177433202 1.0 0.9552454523467628 2 O95394 1 +Unusual skin infection 0.5749342681858124 0.4322588137452734 0.6655533177433202 1.0 0.9552454523467628 2 O95394 1 +Renal angiomyolipoma 0.5749342681858125 0.4322588137452734 0.6655533177433202 1.0 0.9552454523467628 2 P49815 1 +Eversion of lateral third of lower eyelids 0.5731814198071944 0.4267918311295751 0.669530956915652 1.0 0.9572739277433774 2 P61978 1 +Optic disc coloboma 0.4063846158148078 0.4241446319345856 0.6714603374287642 1.0 0.9574820067863044 6 P78318 1 +Abnormality of the choanae 0.2468363544614242 0.4225889301870144 0.672595204558059 1.0 0.9574820067863044 37 Q9NVI1,P42356,Q9UBM7,Q96J02,P78318 5 +Abnormal rib ossification 0.5669199298655706 0.4198870800590701 0.674567946531309 1.0 0.9574820067863044 3 P61011,Q14739 2 +Reduction of neutrophil motility 0.566919929865566 0.4198870800590562 0.6745679465313192 1.0 0.9574820067863044 3 Q7Z2Z2,P61011 2 +Deformed rib cage 0.566919929865566 0.4198870800590562 0.6745679465313192 1.0 0.9574820067863044 3 Q7Z2Z2,P61011 2 +Skin dimple 0.2803287594189326 0.4196403413086104 0.6747482133258269 1.0 0.9574820067863044 24 Q15125,O96028,Q15056 3 +Distal amyotrophy 0.2280607665529685 0.4191646646485706 0.6750957943314742 1.0 0.9574820067863044 66 Q13614,Q99720,Q15813,Q96RL7,Q9Y223,P04792,P38935,Q8TD16,Q8N0X7 9 +Type ii transferrin isoform profile 0.4621212716279183 0.4181899336023524 0.6758082551059195 1.0 0.9574820067863044 4 Q9UP83 1 +Decreased circulating igg level 0.3122039841809183 0.4180455372811916 0.6759138235155933 1.0 0.9574820067863044 14 P50851,P13051,P98170 3 +Brain neoplasm 0.4043908651071356 0.4167249012088578 0.6768796383656364 1.0 0.9579150365918838 6 P28340,Q07864,P21359,Q6PD74 4 +Contractures of the joints of the upper limbs 0.234181412066076 0.4155864966776403 0.6777126093817112 1.0 0.9584430391860752 82 Q96AY3,Q9H4L7,O95155,P46109,Q99720,P41227,Q15392,Q6DKJ4,Q9UP83,Q13535,Q9NPF4,P38935,P07196,P06753,Q01968,A1X283 16 +Abnormal libido 0.5650877698122463 0.4145078712512196 0.6785022036909405 1.0 0.9584430391860752 3 P42858 1 +Muscle fiber inclusion bodies 0.3379489817076203 0.4140914940993349 0.6788071019037702 1.0 0.9584430391860752 10 Q06210,Q9Y281,Q9Y223,P07196,P06753 5 +Areflexia of lower limbs 0.2824101643224471 0.4138419735811914 0.6789898421208893 1.0 0.9584430391860752 23 Q96RL7,Q9Y223,P04792,Q9H6K4,P07196,Q8NCE2 6 +Poor head control 0.2311929095575911 0.4124424138314436 0.6800151808918731 1.0 0.9584430391860752 75 Q9NPL8,P00374 2 +Hepatitis 0.2892787224570164 0.4108978411296702 0.6811474455184627 1.0 0.9593620336149546 20 Q9Y5L0,P98170,P36871,Q9H267,Q13043,Q96J02,Q15477,P08236 8 +Abnormality of the costochondral junction 0.5667543090856043 0.4070257139805129 0.6839891023298161 1.0 0.959940901879432 2 P61011 1 +Enlargement of the costochondral junction 0.5667543090856043 0.4070257139805129 0.6839891023298161 1.0 0.959940901879432 2 P61011 1 +Proximal femoral metaphyseal irregularity 0.5667543090856043 0.4070257139805129 0.6839891023298161 1.0 0.959940901879432 2 P61011 1 +Cafe au lait spot 0.2349454628283602 0.4061319522804382 0.6846456495581363 1.0 0.959940901879432 53 Q9NVI1,Q02750,P52701,Q9BXW9,P42345,Q15645,Q15437,P36507,Q9NXH9,O00232,Q96PZ0,Q06124,Q9Y296,Q7Z6Z7,A1X283,Q15477,Q8N806,P42858 18 +Neoplasm 0.2549272636137481 0.406110981379318 0.684661057408452 1.0 0.959940901879432 236 P48735,Q9NVI1,P08397,O95155,O75874,P98170,P16930,P42771,Q06124,Q9UPY3,Q9UBM7,Q13043,Q15477,P50851,Q9H4L7,P30154,Q02750,P62847,Q15645,Q9NYB0,Q9Y3Z3,Q6PD74,Q13126,P14324,Q13535,O96028,P07437,Q9H9P8,P33991,O43924,P17812,P62899,P06737,P46109,Q15437,P54277,Q92733,P40818,Q01968,Q8NCE2,P62081,Q15555,O95999,Q15392,Q15436,Q01844,O76094,P08708,Q9Y620 49 +Scanning speech 0.4583455130079086 0.4058045909838311 0.6848861851256292 1.0 0.959940901879432 4 O14773,P26367,Q9UBB4 3 +Progressive visual loss 0.2779295907906671 0.4057772338359526 0.6849062878100243 1.0 0.959940901879432 24 Q15051,P03886 2 +Rotary nystagmus 0.4577550560761103 0.4038819935597985 0.6862994980918045 1.0 0.9610446298186816 4 Q14738 1 +Single fiber emg abnormality 0.5612120857298685 0.4032321053421068 0.6867774833358709 1.0 0.9610446298186816 3 Q06210 1 +Muscle fiber tubular inclusions 0.5612120857298685 0.4032321053421068 0.6867774833358709 1.0 0.9610446298186816 3 Q06210 1 +Hashimoto thyroiditis 0.5607314609486325 0.4018436761216666 0.6877990764181132 1.0 0.9614970203663477 3 Q15437 1 +Frontal cortical atrophy 0.2853068085714088 0.40171268905986 0.6878954849156296 1.0 0.9614970203663477 21 Q96RL7,Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 7 +Wide nasal ridge 0.4569036573360595 0.4011165985149874 0.6883342808018396 1.0 0.9614970203663477 4 P27635,P61978 2 +Arteriovenous malformation 0.3523439268389217 0.4008987846705003 0.6884946447382738 1.0 0.9614970203663477 8 Q96HP0 1 +Renal cell carcinoma 0.2769978702498901 0.4004420180618824 0.6888309814619666 1.0 0.9616782757681908 24 Q15437,Q9UPY3,Q92733,Q9Y620 4 +Abnormalities of placenta or umbilical cord 0.2911998694031555 0.3995113758561946 0.6895164433016316 1.0 0.962210824670642 18 Q2TAL8,Q9H4L7 2 +Cavum septum pellucidum 0.3212166099274502 0.399127760844723 0.6897990680552253 1.0 0.962210824670642 12 O96028,Q14738,Q9BVA1 3 +Stridor 0.3748251206683213 0.3963833062236076 0.6918222794033044 1.0 0.962210824670642 7 P38935 1 +Talipes equinovarus 0.2329604033526486 0.3958881458310263 0.6921875464122587 1.0 0.962210824670642 85 Q13614,Q96AY3,P42356,Q15392,P04792,Q15125,O96028,Q8TD16,Q9HD42 9 +Transposition of the great arteries 0.3985394992853265 0.3952417596540641 0.6926644765121679 1.0 0.962210824670642 6 Q2TAL8 1 +Aplasia hypoplasia of the cerebellar vermis 0.2293315331152575 0.394166552687463 0.6934580779520547 1.0 0.962210824670642 75 O43505,Q9UN37,P42356,Q15645,Q9UID3,Q13535,Q15125,Q9UBM7,Q15051 9 +Abnormal vagina morphology 0.2878081650333717 0.3917985565430526 0.6952070616837349 1.0 0.9627173149019214 19 Q9UBM7 1 +Intestinal polyp 0.285660905467535 0.3914447621546038 0.6954685110931382 1.0 0.9627173149019214 20 Q07864,Q16658,P52701,P42345,Q15645,O60566,Q15437,P54277,P42771,Q9UPY3 10 +Short foot 0.2490933220442129 0.3910302807182672 0.6957748534929726 1.0 0.9627173149019214 31 Q8N0X7,O95155,Q14320,P42858 4 +Abnormality of the pulmonary artery 0.2396266453874688 0.3910256180196535 0.6957782999667022 1.0 0.9627173149019214 41 P41227,P27635,Q96HP0,Q9NXH9,Q15056,O00232,Q96PZ0,Q06124,Q9Y296,Q7Z6Z7,Q15477,Q8N806,P42858 13 +Pulmonary artery dilatation 0.2912189766428982 0.3905154502708237 0.6961554327832342 1.0 0.9627888474027744 17 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 6 +Developmental cataract 0.2296019477033164 0.390116568322885 0.696450351815409 1.0 0.9627888474027744 60 P18074,Q9UN37,P62899,P62081,P46783,P62847,P39019,Q01968,P36507,Q96HP0,Q15042,O00400,Q9Y4R8,P17980,P08708,Q16134,P03886 17 +Hematological neoplasm 0.2321302070388827 0.3897390450493256 0.6967295212845537 1.0 0.9628888842685908 84 Q9NVI1,P98170,P42771,Q06124,P50851,Q02750,P62847,Q15645,Q9Y3Z3,Q6PD74,P33991,P17812,Q07864,P62899,P62081,O95999,O76094,P08708,Q9Y620 19 +Hypoplasia of the fovea 0.5609114811568916 0.3894476008946023 0.6969450653942888 1.0 0.9629009568177472 2 Q16851 1 +Hand muscle weakness 0.3125873993018241 0.3886968373909097 0.6975004221582686 1.0 0.9630966683181788 13 Q8TD16,P07196,Q9Y223 3 +Abnormal lateral ventricle morphology 0.2426720813200438 0.3884053802556696 0.6977160632920509 1.0 0.9631088024570972 36 Q9NVI1,Q01105,Q9BVA1,Q96RL7,Q9UP83,Q9UID3,Q14738,Q15042,Q05639 9 +Acne inversa 0.4524992692195305 0.3869419458795901 0.6987991869286936 1.0 0.9643180244042672 4 O14920,Q9H488,Q92542 3 +Limitation of joint mobility 0.2281644410280611 0.385570526277357 0.6998147650724411 1.0 0.964861577191971 110 P48735,Q96AY3,O95155,P15586,O75874,Q15056,Q13535 7 +Dilation of lateral ventricles 0.267409723734774 0.3829798632570738 0.7017346946973688 1.0 0.965462857918818 26 Q01105,Q9BVA1,Q96RL7,Q9UP83,Q9UID3,Q14738,Q05639 7 +Slurred speech 0.3478470182681997 0.3823183791249793 0.7022252237227398 1.0 0.965462857918818 8 Q8N0X7 1 +Abnormal large intestine morphology 0.2303336299573823 0.3801995498330467 0.703797293379365 1.0 0.9665717375446288 81 P98170,P42771,Q9UPY3,Q13043,Q15477,P50851,P62847,Q15645,Q6PD74,Q15056,Q07864,P62899,Q15437,P54277,P62081,O95999,P41227,P08708,Q9Y620 19 +Abnormal circulating igg level 0.2905922855604994 0.3793872439583421 0.7044003216469517 1.0 0.9665717375446288 16 P50851,P13051,P98170 3 +Abnormal phalangeal joint morphology of the hand 0.2341523684285835 0.3789786105404381 0.7047037474958266 1.0 0.9665717375446288 45 Q9H4L7,O95155,P46109,P41227,Q6DKJ4,Q9UP83,Q9NPF4,P38935,Q01968,A1X283 10 +Abnormality of the hallux 0.2288225720164338 0.3778835830290005 0.7055170786282488 1.0 0.9665717375446288 59 P41227,Q9NXH9,Q6DKJ4,Q15056,P04792,Q9Y223,Q9Y296,Q15125,Q96J02,O96028,P42858 11 +Abnormal urinary color 0.3699133646924091 0.377500185572097 0.7058019265015731 1.0 0.9665717375446288 7 P53004,P08397 2 +Abnormality of long bone morphology 0.2317610812305514 0.3771831868567666 0.7060374740956363 1.0 0.9665717375446288 188 P48735,Q9NVI1,O75874,Q9NXH9,Q9UP83,Q9UBM7,Q96J02,Q96AY3,Q02750,Q9H4A3,Q15813,Q13126,Q15056,Q13535,Q15125,O96028,P42858,P46109,Q6DKJ4,Q01968,O95831,Q2TAL8,Q15051,Q8N0X7 24 +Recurrent skin infections 0.284861463375198 0.3764125426087437 0.7066102228585671 1.0 0.9667315959547836 19 O00203,P98170 2 +Prolonged bleeding time 0.335680284706281 0.3760246309376742 0.7068985847016962 1.0 0.9667315959547836 9 Q86YV9,O00203 2 +Prominent nose 0.2661158873158932 0.3754390178049429 0.7073339915257164 1.0 0.9667315959547836 26 Q13535,Q2TAL8,Q8N0X7 3 +Dilated fourth ventricle 0.2336690569988141 0.3752486027483242 0.7074755868777658 1.0 0.9667315959547836 45 Q9UID3,Q15125,Q9UBM7,O43505 4 +Facial asymmetry 0.240672924881511 0.3743706830652544 0.7081285512697177 1.0 0.9668137096733272 36 Q9NVI1,Q01105,Q96JJ3,P30153,P46109,Q9BXW9,O00232,Q14738,Q13535,A2RRP1,O96028 11 +Aplasia hypoplasia of the spleen 0.3925080952734358 0.3735721468195304 0.7087226595981275 1.0 0.9668137096733272 6 Q7L590,Q86Y56 2 +Esodeviation 0.2383907252948525 0.3707605342372823 0.7108158986722528 1.0 0.9678182809715504 39 O15347,Q14738,Q9H1B7,Q15436,Q9UBB6,Q9Y4R8,Q16512,O43924,Q9HD42 9 +Gout 0.4225474394846874 0.3676009354878143 0.7131708171780453 1.0 0.9681985785950792 5 P08237,P60891 2 +Recurrent staphylococcus aureus infections 0.5524393806602497 0.3646453777808501 0.7153761371616074 1.0 0.9688165487563828 2 O95394 1 +Recurrent staphylococcal infections 0.5524393806602497 0.3646453777808501 0.7153761371616074 1.0 0.9688165487563828 2 O95394 1 +Aplasia hypoplasia involving bones of the feet 0.2239305991146109 0.3634806515293889 0.7162458638579012 1.0 0.9693248933339156 71 O95155,Q96HP0,Q9UBM7,O96028,Q14320,Q8N0X7 6 +Cone shaped epiphysis 0.3067529035781894 0.362376791704137 0.7170704801879522 1.0 0.9693916820553448 13 Q13535,Q15051 2 +Slowly progressive 0.224342058150746 0.3616155294855654 0.717639358123046 1.0 0.9693916820553448 63 Q99720,Q8IV08,P04792,P38935,P07196,Q8NCE2,P46976,O95831 8 +Renal cortical microcysts 0.5512708150745087 0.3612897656797942 0.7178828435839406 1.0 0.9693916820553448 2 Q6PGP7 1 +Cystic renal dysplasia 0.5512708150745086 0.361289765679794 0.7178828435839408 1.0 0.9693916820553448 2 P23786 1 +Convex nasal ridge 0.2714802687011297 0.353715350455015 0.7235522173982352 1.0 0.973658706417972 23 O96028,Q13535,Q96J02 3 +Fibrous tissue neoplasm 0.2737565380141539 0.3526318784195433 0.7243644354288912 1.0 0.9738129329677484 22 Q15392,Q13126 2 +Ankle clonus 0.3102449688222267 0.3512483500771682 0.7254020398983418 1.0 0.9738961642925836 12 Q8N0X7 1 +Facial edema 0.2506759782546689 0.3486698313285825 0.7273371956736425 1.0 0.9748077095729648 29 P28070 1 +Broad foot 0.3391268722493489 0.347267156521001 0.7283906225372523 1.0 0.9756578649405772 8 P27635,O00170,O95831 3 +Hypouricemia 0.3846666203567914 0.3461574165841171 0.7292244152896445 1.0 0.9761258163136524 6 Q96EN8,Q08426,P00491,P60891 4 +Pelvic girdle muscle weakness 0.3212088525673865 0.3425608370165765 0.7319288687443664 1.0 0.9775848573935082 10 O75190,P06753,Q9Y223 3 +Hyperhomocystinemia 0.5382817066043105 0.3395386078434314 0.7342040177570994 1.0 0.9792191081859224 3 P23526,Q99707 2 +Aplasia hypoplasia affecting the eye 0.2256614937060787 0.338826114999028 0.7347407268174524 1.0 0.9794650539578148 106 Q9NVI1,O43505,Q9UBC2,O15347,Q15555,Q15645,Q15813,Q96HP0,Q15056,Q15125,Q9UBM7,O96028,Q01968,O43924,O95721 15 +Scrotal hypoplasia 0.2774338484974785 0.3387352852590714 0.734809156674108 1.0 0.9794650539578148 19 Q9UBM7 1 +Amaurosis fugax 0.3365868335333015 0.3373117034419216 0.7358819380937374 1.0 0.9803337063703694 8 P54277,P52701 2 +Abnormal stomach morphology 0.227079044941183 0.3359609785089435 0.7369002925054429 1.0 0.9808532784295758 86 P50851,P46821,O95155,P46109,O95999,P41227,Q15645,Q9NYB0,Q6PD74,Q15056,P42771,Q9UBM7,Q9NPF4,Q8NCE2,Q15477,Q9Y620,Q96PU5 17 +Elfin facies 0.3586682804438486 0.335676791043189 0.737114609369649 1.0 0.9808532784295758 7 Q15056 1 +Periorbital edema 0.252056320693909 0.3346995991881559 0.7378517038304473 1.0 0.9815453254597348 28 P28070 1 +Agyria 0.4121958634782161 0.3343744736073328 0.7380969990932709 1.0 0.9815453254597348 5 P43034,Q00535 2 +Degeneration of the striatum 0.43507415180915 0.3331246289440518 0.739040208913925 1.0 0.9818478329623158 4 P42858 1 +Cerebellar hypoplasia 0.2024486076287973 0.3330112168033856 0.7391258161636292 1.0 0.9818478329623158 135 P00374,P42356,Q96HP0,Q9UID3,Q15125,Q13535,Q9UBM7,Q8TD16,Q9HD42 9 +Premature skin wrinkling 0.2780528852244155 0.3330092665012828 0.7391272883446987 1.0 0.9818478329623158 18 Q02750,P41227,P37837,Q9UP83,Q06124 5 +Abnormal circulating methionine concentration 0.3797856521440461 0.3295460728765191 0.7417429757459921 1.0 0.9827988887516618 6 Q99707,P55263,Q6PGP7,P16930 4 +Chorioretinal hypopigmentation 0.4334989769073464 0.3284463320087157 0.7425742162832174 1.0 0.9828255176762236 4 P26367,Q96AX1,P49815 3 +Tritanomaly 0.5336693974866253 0.3273843759926892 0.7433771821054946 1.0 0.9828255176762236 3 Q9H6K4 1 +Anomalous trichromacy 0.5336693974866253 0.3273843759926892 0.7433771821054946 1.0 0.9828255176762236 3 Q9H6K4 1 +Prominent digit pad 0.2633401438562363 0.3255684492755449 0.7447508864966956 1.0 0.9828981713514542 24 P46821,P41227,Q9NXH9,O00232,Q96PZ0,Q9Y296,P62266,Q7Z6Z7,P42858 9 +Abnormal vestibulo ocular reflex 0.5381244522348954 0.3246704432913305 0.745430506635274 1.0 0.9831073189523408 2 P35251 1 +Triangular face 0.2327114896263538 0.3234800109637652 0.7463317434321435 1.0 0.9832414161773406 37 Q9NVI1,Q96AY3,Q02750,Q15645,P37837,Q06124,Q4G0J3 7 +Abnormal cerebellar vermis morphology 0.2254503674895709 0.3225000522308188 0.7470738981921081 1.0 0.9836604379230406 85 O43505,Q9UN37,P42356,Q15645,Q9UID3,Q15125,Q13535,Q9UBM7,Q15051,P42858 10 +Abnormality of globe size 0.2174702960744323 0.3222644587002066 0.7472523558706603 1.0 0.9836604379230406 68 Q9NVI1,O43505,O15347,Q15555,P41227,Q15645,Q96HP0,Q13535,Q15125,Q9NPF4,P07437,Q01968,A1X283,O43924 14 +Abnormality of hair texture 0.2244533429113626 0.3207344965881509 0.7484116027757997 1.0 0.9840735449093824 53 P46778,P49589,P15586,P42345,P36507,Q06124,Q15477,Q02750,Q6PGP7,Q15125,P18074,P04080,P26639,Q93008,Q01968,P41227,P62266,Q15436,A2RRP1 19 +Lymphoproliferative disorder 0.4075824991309557 0.3200302250429374 0.7489454182363127 1.0 0.9842195504680418 5 P50851,P17812 2 +Protruding tongue 0.2907912019425482 0.3191529413516091 0.7496105396812056 1.0 0.984815652583435 14 P42356,Q96RL7 2 +Preaxial polydactyly 0.2779472411793552 0.318032451096468 0.7504603214242536 1.0 0.985031679093311 16 Q9UPP1,O96028 2 +Prominent supraorbital ridges 0.2961369493431527 0.3165043217180588 0.7516197453943005 1.0 0.9852932387219916 13 Q9UPP1,P36507,Q9HCK8,Q15436,P17980 5 +Abnormal circulating iga level 0.2961220940646809 0.3164420464554957 0.7516670068600759 1.0 0.9852932387219916 13 P50851,P42345,Q96J02,P13051 4 +Excessive daytime somnolence 0.2822399333948062 0.3085880639648971 0.7576349015985717 1.0 0.9884615575777468 15 P41227,Q9UBM7,P42858 3 +Nasal speech 0.2264176740457256 0.3078285929480975 0.7582127633173328 1.0 0.9884615575777468 43 Q9UPP1,Q9NXH9,O95817,Q13409,Q96PZ0,Q9Y296,Q4J6C6,P06753,Q7Z6Z7,Q96IJ6,P42858 11 +Autism 0.2228968394925783 0.3054303245496286 0.7600384288464697 1.0 0.9887747845467368 51 O14874,O95155,Q15437,Q15056,Q9UBM7 5 +Hypermethioninemia 0.4010729756256244 0.3002978858937732 0.7639499456774366 1.0 0.9908573809009829 5 P55263,P16930 2 +Aortic regurgitation 0.2514924211568605 0.2946411041001054 0.7682680587782835 1.0 0.9922485663444348 26 Q15645,P46109,Q96PU5 3 +Distal muscle weakness 0.2162037751780387 0.2933877261000345 0.7692258060499146 1.0 0.9926594659003332 71 Q13614,Q99720,Q96RL7,Q9Y223,P04792,P38935,Q8TD16,P46976,O95831 9 +Abnormal uvula morphology 0.2222314233322453 0.2911649949913695 0.7709251332235718 1.0 0.9943012244567728 45 Q9NVI1,O43505,Q15813,Q15392,Q6DKJ4,P78318 6 +Abnormal thyroid stimulating hormone level 0.5241016652059742 0.2879919477481206 0.7733529024432317 1.0 0.9949519518584397 2 O14654 1 +Neoplasm of the heart 0.5241016652059736 0.2879919477481188 0.7733529024432331 1.0 0.9949519518584397 2 P49815 1 +Severe viral infection 0.3447624632199608 0.2868869570064912 0.7741988777040041 1.0 0.9953413258046264 7 P17812,P98170 2 +Abnormal bronchus physiology 0.3664300721032281 0.2859786899598142 0.7748944431973745 1.0 0.9953413258046264 6 P18074,Q9UER7 2 +Bronchospasm 0.3664300721032281 0.2859786899598142 0.7748944431973745 1.0 0.9953413258046264 6 P18074,Q9UER7 2 +Incomitant strabismus 0.2662721297031753 0.285320642159541 0.7753984996839871 1.0 0.9955030621707652 19 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 6 +Abnormal circulating aspartate family amino acid concentration 0.32142932009186 0.2804671936520684 0.779119091495565 1.0 0.9985167035207294 8 Q99707,P55263,Q6PGP7,P16930 4 +Short fourth metatarsal 0.5149035651665547 0.2803621027656394 0.7791997091787868 1.0 0.9985167035207294 3 Q96DX4,Q9NQ48 2 +Impaired horizontal smooth pursuit 0.4165426604443086 0.280178486224255 0.7793405714334902 1.0 0.9985167035207294 4 P35251 1 +Acute phase response 0.2383836443979578 0.2779225780445417 0.7810717916449077 1.0 0.9990852367853544 29 P98170,Q01968,Q969U7,P28070,P14174,P51617 6 +Incisor macrodontia 0.2640699908980227 0.2752668922224879 0.7831111984565235 1.0 0.9997350333497986 19 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 6 +Low posterior hairline 0.2247595088738487 0.2751705590810533 0.7831852046200725 1.0 0.9997350333497986 38 Q02750,Q9UPP1,P36507,Q9Y223,Q9UID3,Q06124,O96028,Q15042 8 +Abnormal t cell morphology 0.2683056347053718 0.2743507704808807 0.7838150714477268 1.0 0.9997350333497986 16 P00491,O95999,O00203,Q13546,P17812 5 +Decreased cd4 cd8 ratio 0.5123726202203386 0.2743285965253467 0.7838321102962194 1.0 0.9997350333497986 3 O00203 1 +Colon cancer 0.2653263963175349 0.2735554902616454 0.7844262431839755 1.0 0.9997350333497986 18 Q16658,P52701,Q15645,P54277,Q8WX93,P39019,P42771,Q5HYI8 8 +Abnormality of the neck 0.2171388701705826 0.2731516168130907 0.7847366702994936 1.0 0.9997350333497986 175 Q9NVI1,O95155,P15586,Q99720,Q9UP83,Q9UID3,Q06124,Q9UBM7,P83436,Q02750,P62847,Q15056,Q14738,Q15125,Q96EK5,O96028,P07437,A1X283,P78318,Q07864,P62899,P46109,P37837,Q6DKJ4,Q15042,O95831,Q00535,P62081,Q15555,P41227,Q9UPP1,Q9Y223,P08708 33 +Broad toe 0.2259286157036188 0.2730246231744283 0.7848342878289154 1.0 0.9997350333497986 33 P30153,P41227,Q9NXH9,Q93008,O00232,Q96PZ0,Q9Y296,Q15125,Q7Z6Z7,P42858 10 +Flexion contracture of digit 0.2166437998867074 0.2727283664265233 0.785062027759639 1.0 0.9997350333497986 76 Q9H4L7,O95155,P46109,P41227,Q6DKJ4,Q9UP83,Q14738,Q9NPF4,P38935,P07196,Q96J02,P06753,P63241,Q01968,A1X283,Q8N0X7 16 +Eeg with polyspike wave complexes 0.3399280182140889 0.2707385744700595 0.7865921062636001 1.0 0.9997350333497986 7 P42356 1 +Cleft soft palate 0.213731066824789 0.2666008516793074 0.789776499817906 1.0 0.9997350333497986 62 O43505,P62081,P62899,Q15813,Q15392,Q15436,P08708,P78318 8 +Decreased circulating antibody level 0.2175296756355691 0.2649481437852686 0.7910494097828054 1.0 0.9997350333497986 47 P11586,P50851,P18074,P26038,Q6PGP7,O95999,P98170,P42345,Q9UJW0,P21266,Q96J02,P13051,P14174,Q15477,Q13546,P17812 16 +Wormian bones 0.2617532440557296 0.2648700370260125 0.7911095811633659 1.0 0.9997350333497986 19 Q9H4A3,Q96AY3,O95831 3 +Deeply set eye 0.2151068157064612 0.2639587872997902 0.7918116757314873 1.0 0.9997350333497986 75 P54577,P49589,O95155,Q96C86,P35573,P63241,Q16512,Q4G0J3,P60891,Q8IWS0,Q15813,Q9Y3C4,O00232,Q14738,Q9UHD8,A1X283,Q05639,P18074,P46109,Q9H490,P78527,Q01968,Q13045,Q7Z6Z7,Q15042,O60701,Q9Y285,Q96PZ0,Q9NPF4,Q8IYU2 30 +Focal emotional seizure 0.3068190781298401 0.2624123634672536 0.7930035419046306 1.0 0.9997350333497986 9 Q01105,Q12756,Q05639 3 +Profound sensorineural hearing impairment 0.3876996276718449 0.2617080555502041 0.7935465295103492 1.0 0.9997350333497986 5 P60891 1 +Oligohydramnios 0.2235934259092468 0.2615095980637517 0.793699548795447 1.0 0.9997350333497986 35 Q9NVI1,Q9Y285,P51114,Q96HP0,P37837,Q9UP83 6 +Decreased fertility in males 0.2872858242901255 0.2600028133029132 0.7948616035089804 1.0 0.9997350333497986 12 Q9NVI1,Q02750,Q86Y56,O00170,Q06124 5 +Abnormal renal pelvis morphology 0.2147383151707431 0.2592378939511155 0.795451695042481 1.0 0.9997350333497986 58 P83436,Q07864,O43505,Q02750,O95155,P41227,Q6DKJ4,Q15125,Q9UBM7,Q15042,Q8N0X7 11 +Cerebellar vermis atrophy 0.2934260604208847 0.2591998735807295 0.795481028639391 1.0 0.9997350333497986 11 P07437,P42858 2 +Male infertility 0.3363498250940049 0.2590696981537226 0.7955814641872938 1.0 0.9997350333497986 7 Q02750,Q86Y56 2 +Abnormality of the septum pellucidum 0.2183495149904086 0.2588708135707319 0.7957349181370768 1.0 0.9997350333497986 44 Q9NVI1,Q96F86,O43505,Q9BVA1,Q96C86,P49591,Q15392,Q14738,P43034,O96028,Q9UBB6 11 +Long clavicles 0.504856978664229 0.2568582851724859 0.7972881739743307 1.0 0.9997350333497986 3 Q15813 1 +Recurrent viral infections 0.286051530501217 0.255472760211862 0.7983579799339466 1.0 0.9997350333497986 12 P33991,Q13043,P17812 3 +Cortical dysplasia 0.2219144834234504 0.2551641837939741 0.798596292807032 1.0 0.9997350333497986 37 Q96F86,O43505,Q9BVA1,Q96C86,P49591,Q9UBB6,P07437,Q96PU5,O95721 9 +Chronic lung disease 0.3046727501539887 0.2546727008484461 0.7989759027167151 1.0 0.9997350333497986 9 P50851,Q96J02 2 +Antineutrophil antibody positivity 0.3846766690103908 0.253362325010357 0.7999882383075174 1.0 0.9997350333497986 5 P49327,Q96J02,P51617 3 +Absent toe 0.2369283258429305 0.2522273835002722 0.8008653131900232 1.0 0.9997350333497986 28 Q96HP0,Q9NXH9,O96028,P42858 4 +Pyoderma gangrenosum 0.509202453987746 0.251852779381189 0.8011548598117999 1.0 0.9997350333497986 2 P61011 1 +Abnormal shoulder morphology 0.2219457259881286 0.2518160980288714 0.8011832137765287 1.0 0.9997350333497986 35 P46821,Q9NXH9,Q15056,Q9Y296,Q96PU5,P42858 6 +Sparse and thin eyebrow 0.2791852208832871 0.2491892877689057 0.803214365247912 1.0 0.9997350333497986 13 Q96EK5,Q15125 2 +Ankyloblepharon 0.3325814897547472 0.2470474104255548 0.8048715327453722 1.0 1.0 7 P18074,P41227,O75569 3 +Vasculitis 0.2897431213616031 0.2459051124236628 0.8057556861887956 1.0 1.0 11 Q9Y3Z3,P98170 2 +Prematurely aged appearance 0.2188250898065069 0.2446728754923619 0.8067097319925218 1.0 1.0 40 Q02750,P41227,P37837,Q13126,Q15056,Q9UP83,Q13535,Q06124,Q15042 9 +Intestinal pseudo obstruction 0.2827099635615075 0.2434128342725698 0.807685602441756 1.0 1.0 12 P03886 1 +Elevated urinary delta aminolevulinic acid 0.4021118575124592 0.242277752427557 0.8085649513143096 1.0 1.0 4 P16930 1 +Abnormality of chromosome segregation 0.351937239488748 0.2420395291917534 0.8087495338001114 1.0 1.0 6 Q15437 1 +Female sexual dysfunction 0.4016800925164843 0.2411908286940861 0.8094072187552666 1.0 1.0 4 Q99497 1 +Decreased circulating level of specific antibody 0.3515199680129324 0.2408285734807018 0.8096879828445955 1.0 1.0 6 P50851,P17812 2 +Emg myopathic abnormalities 0.2242299664272252 0.2408175168687466 0.8096965526017355 1.0 1.0 31 P51114,O95817,Q9Y223,Q8NCE2,P46976 5 +Limited hip movement 0.2587501487362169 0.2339606666899194 0.8150155146838738 1.0 1.0 16 Q96AY3 1 +Duplicated collecting system 0.3482814116500805 0.2315360090064635 0.8168984141806239 1.0 1.0 6 Q9Y4R8 1 +Narrow palm 0.4925174816012387 0.229653550998692 0.8183609911174057 1.0 1.0 3 Q9BPU6 1 +Abnormal iris pigmentation 0.2458789818397677 0.2294590714406306 0.8185121282599577 1.0 1.0 23 O00203,O95155,Q15056 3 +Long thorax 0.3963436613405091 0.2279880785916554 0.8196555083940729 1.0 1.0 4 P41227 1 +Abnormality of the ankles 0.211823279168291 0.2277078692174821 0.8198733543923622 1.0 1.0 46 Q96AY3,Q8N0X7,Q9HD42,Q15056 4 +Chromosomal breakage induced by crosslinking agents 0.4904548616225742 0.225288705862113 0.8217546852668638 1.0 1.0 3 Q9NVI1 1 +Anophthalmia 0.2833834499369466 0.2237732578385481 0.8229337394719234 1.0 1.0 11 O43505 1 +Aplasia hypoplasia involving bones of the lower limbs 0.2157008391912751 0.2235710950607534 0.8230910571562648 1.0 1.0 95 Q96AY3,O95155,Q96HP0,Q13535,Q9UBM7,O96028,Q14320,Q8N0X7 8 +Abnormal sacrum morphology 0.2277810494710559 0.2228384292692169 0.8236612576800209 1.0 1.0 29 Q15125,O96028,Q15056 3 +Mediastinal lymphadenopathy 0.37175510869231 0.2193242961781336 0.8263974369959466 1.0 1.0 5 Q01844 1 +Neoplasm of the larynx 0.3710663985843173 0.217586070791808 0.8277516383767853 1.0 1.0 5 O96017,P42771,P52701 3 +Obsessive compulsive behavior 0.2117888091258473 0.217351245802113 0.8279346231327245 1.0 1.0 44 Q6DKK2,P46109,Q96RL7,Q15056,Q01968,P42858 6 +Abnormal circulating sulfur amino acid concentration 0.3023863372252031 0.2158438213240938 0.8291094888550672 1.0 1.0 8 Q99707,P55263,Q6PGP7,P16930 4 +Cerebral hypomyelination 0.2541812606080778 0.2157301555190904 0.8291980939395256 1.0 1.0 16 P49770,Q13144,Q9NR50,Q14232 4 +Impaired mastication 0.3423115489622154 0.2149052562219182 0.8298411867656541 1.0 1.0 6 Q14738 1 +Female reproductive system neoplasm 0.2482485902686151 0.2146439113938712 0.8300449554192466 1.0 1.0 20 Q07864,Q15645,Q15437,O14965,Q9Y620 5 +Puberty and gonadal disorders 0.2073642641338013 0.2142597384148049 0.8303445130332552 1.0 1.0 166 P48735,Q9NVI1,O95155,O75874,Q15555,Q15056,Q4J6C6,Q9UBM7,O96028,P04150,P03886,P42858 12 +Abdominal wall muscle weakness 0.369383943564463 0.2133726472794266 0.8310363135590699 1.0 1.0 5 P46976 1 +Abnormal bone structure 0.2157669217130576 0.2132837673179563 0.8311056340742586 1.0 1.0 182 P48735,Q9NVI1,O75874,P16930,Q9UBM7,Q96AY3,Q02750,Q00534,Q15645,Q15813,Q9H4A3,Q13126,Q15056,Q15125,O96028,P06737,Q15437,O43379,Q01968,O95831,Q15392,Q15436,Q15051 23 +Ragged red muscle fibers 0.2510259896911216 0.213242487253156 0.831137830252505 1.0 1.0 18 P03886,Q9H2D1 2 +Deep plantar creases 0.3684131661201928 0.2109628143767387 0.8329162881351508 1.0 1.0 5 P42345,O00170 2 +Aplasia hypoplasia involving the skeletal musculature 0.2917626037575264 0.2104064637875899 0.8333504481995193 1.0 1.0 9 O43505 1 +Profound global developmental delay 0.2524908928441436 0.209168732121177 0.8343165206677863 1.0 1.0 16 P83436,P40855,Q9H490,Q9Y4R8,P60891 5 +Pulmonary fibrosis 0.2448628261327926 0.2081611132631242 0.8351031706043364 1.0 1.0 21 Q86TI2,Q9UJW0,P21266,O00203,P14174 5 +Right ventricular hypertrophy 0.3664799129262879 0.2062104279377063 0.8366265425811183 1.0 1.0 5 Q969Y2 1 +Respiratory failure requiring assisted ventilation 0.3390916141021203 0.206208207873347 0.8366282766726998 1.0 1.0 6 P38935,P60891 2 +Melanoma 0.2423622553192982 0.2058232368791744 0.8369289893938276 1.0 1.0 22 P42771,Q15437,Q9NYB0 3 +Emg axonal abnormality 0.4796054583431695 0.2032053968347382 0.8389744947728972 1.0 1.0 3 Q9Y223 1 +Nonimmune hydrops fetalis 0.2264442148326203 0.2015756814058476 0.8402484583815875 1.0 1.0 28 P62081,P62899,P46783,Q7L590,P39019,P62847,P08708 7 +Defective dna repair after ultraviolet radiation damage 0.3838001750948189 0.1986697138734153 0.8425211165711601 1.0 1.0 4 P18074 1 +Numerous pigmented freckles 0.3838001750948189 0.1986697138734153 0.8425211165711601 1.0 1.0 4 P18074 1 +Increased connective tissue 0.2961353782510038 0.1964177405944744 0.844283211720712 1.0 1.0 8 P07196,O95831,P31751 3 +Abnormal right ventricle morphology 0.2869273764932628 0.1948750155946521 0.8454907938648437 1.0 1.0 9 Q969Y2,P06753,Q9H267 3 +Microcornea 0.221770741174372 0.1942552541380889 0.8459760202194693 1.0 1.0 29 O43505,O15347,Q15555,P41227,Q15125,P07437 6 +Abnormal midbrain morphology 0.2866664919994582 0.1940537336842441 0.8461338080910663 1.0 1.0 9 Q15813 1 +Relative macrocephaly 0.210207658237464 0.1925313561214734 0.8473260086984455 1.0 1.0 39 Q07864,Q15392,Q9NXH9,Q6DKJ4,O00232,Q96PZ0,Q9Y296,Q96J02,Q99575,Q7Z6Z7,P42858 11 +Abnormal hand morphology 0.2044678883995824 0.1910532127258813 0.8484839031841793 1.0 1.0 119 Q9NVI1,P83436,P62081,P42356,P62899,P46109,Q9UPP1,Q96HP0,Q6DKJ4,Q15125,P08708,Q9UBM7,O96028,Q14320,Q8TD16,Q8N0X7,O95831 17 +Hip dysplasia 0.2054422043582351 0.1894937984046835 0.8497058152047259 1.0 1.0 56 O95155,Q13535,Q15125,O96028,Q8TD16 5 +Absent septum pellucidum 0.2104105535104359 0.1894400918487528 0.8497479045599643 1.0 1.0 36 Q96C86,O43505,Q15392,O96028 4 +Molar tooth sign on mri 0.359307390334649 0.1891266562671462 0.849993549805353 1.0 1.0 5 P36405,O43924,Q96KP1 3 +Decreased fertility 0.2203720159504086 0.1878883167521181 0.8509642015134489 1.0 1.0 29 Q9NVI1,Q02750,Q15645,Q86Y56,P40818,Q06124,O00170,P04150 8 +Sprengel anomaly 0.2169267400439796 0.1867304687761011 0.851871965626223 1.0 1.0 30 P62081,P62899,P62847,P39019,Q06124,P08708 6 +Abnormality of the nasal dorsum 0.2049772423404591 0.1864696566513875 0.8520764720060829 1.0 1.0 56 O95155,Q15645,Q15813,Q13535,Q15125,Q96J02,O96028 7 +Polyneuropathy 0.2408764896049389 0.1858079756197295 0.852595349812409 1.0 1.0 20 P03886,O95721 2 +Abnormal dermatoglyphics 0.2082070660780424 0.1855747600885645 0.8527782482577975 1.0 1.0 81 P42345,P36507,Q9UID3,Q06124,Q9UBM7,Q96J02,Q9H4L7,Q02750,Q96HP0,Q15056,Q13535,O96028,Q9Y4R8,Q6DKJ4,O00170,Q15042,P46821,P41227,P62266,A2RRP1 20 +Abnormal tracheobronchial morphology 0.2036561486436021 0.1855231342905761 0.8528187366754738 1.0 1.0 60 Q9NVI1,P30154,Q86TI2,Q15056,Q15125,Q9UBM7 6 +Acute leukemia 0.2056676838576637 0.1854416722866737 0.8528826254381447 1.0 1.0 45 P62081,P62899,Q15645,P42771,P08708 5 +Apraxia 0.2003923999127775 0.1835910475785588 0.8543342867430712 1.0 1.0 66 P42356,Q6DKK2,P46109,Q12873,Q9NXH9,P35270,Q8N0X7,O14646,O43924,P42858 10 +Polysplenia 0.4691225124272068 0.183282439164526 0.8545764125195954 1.0 1.0 3 Q86Y56 1 +Abnormality of skin pigmentation 0.1901372482052502 0.1827275572794668 0.8550117922055471 1.0 1.0 141 Q9NVI1,Q96C86,Q9NXH9,P42771,Q06124,Q96IJ6,Q15477,P03886,P50851,Q96AY3,Q9H4L7,Q02750,Q15645,Q9NYB0,Q15125,Q9Y296,P07437,A1X283,P33991,P42858,Q15437,P40818,O00203,Q01968,O14617,Q15555,Q15436 27 +Severe infection 0.2767521633295756 0.1823795307073281 0.8552848885322033 1.0 1.0 10 P60891,P17812,P98170 3 +Decreased circulating copper concentration 0.4747297692083154 0.1800079331953248 0.8571463401447919 1.0 1.0 2 Q15904 1 +Otitis media 0.2027270487072026 0.179280863435482 0.8577171721756824 1.0 1.0 60 P50851,P41227,Q6DKJ4,Q15056,O00203,Q9UBM7,O96028,Q01968 8 +X linked recessive inheritance 0.2040815049672601 0.1786614603924675 0.8582035323621646 1.0 1.0 54 P98170,Q9UPP1,Q15125,Q14320,Q01968,P78318 6 +Basal cell carcinoma 0.2493035556310579 0.178659323451839 0.858205210398183 1.0 1.0 15 P18074,P52701,P54277,Q6PD74,Q9UPY3 5 +Abnormality of exocrine pancreas physiology 0.2402257282465945 0.177645905609643 0.8590010704276847 1.0 1.0 19 Q9UJW0,P21266,P42771,P14174,Q5HYI8 5 +Cellular immunodeficiency 0.2811824662000276 0.1771917376198604 0.8593577854017951 1.0 1.0 9 Q15437 1 +Abnormality of urine calcium concentration 0.2535353075228859 0.1767769950216188 0.8596835597603509 1.0 1.0 14 Q9UNF1,Q01968,Q15056 3 +Periodontitis 0.2805891837860966 0.1754139379612631 0.8607543894740222 1.0 1.0 9 O00203 1 +Oromotor apraxia 0.3519867367490398 0.1725918809380013 0.8629722341979482 1.0 1.0 5 P42356 1 +Inguinal freckling 0.4685947998831623 0.168986847169466 0.8658069870501748 1.0 1.0 2 P21359 1 +Hypomelanotic macule 0.4685947998831557 0.1689868471694547 0.8658069870501837 1.0 1.0 2 P49815 1 +Reticular hyperpigmentation 0.4685947998831538 0.1689868471694513 0.8658069870501863 1.0 1.0 2 P09884 1 +Abnormal leukocyte physiology 0.1991140565445129 0.1682268147894987 0.8664048464026974 1.0 1.0 69 P50851,O95999,P98170,Q9UJW0,P21266,O00203,P28070,Q13043,Q96J02,P13051,P14174,Q15477,Q13546,P17812 14 +Aplasia hypoplasia of the uvula 0.3239890202485949 0.1680393236736001 0.8665523430940265 1.0 1.0 6 Q9NVI1 1 +Mood swings 0.3497076023391849 0.1676321483585427 0.8668726783318821 1.0 1.0 5 Q13620,Q96DF8,Q8WYQ5,O00232 4 +Keratitis 0.2548926085247383 0.1670079385209181 0.8673638026174495 1.0 1.0 13 P18074,P49327,Q14739,P26639,P50747,P06132,Q9NZ08 7 +Posteriorly rotated ears 0.203608262115982 0.1668926617228824 0.8674545072672231 1.0 1.0 116 O95155,Q9UP83,Q06124,Q9UBM7,Q96J02,Q02750,Q15645,Q15813,Q15056,O96028,P07437,O43924,Q07864,O43505,Q6DKJ4,O00203,Q9H490,Q4J6C6,Q01968,P46821,Q15555,P41227,Q15392 23 +Abdominal obesity 0.3225009072505661 0.1645167259048875 0.8693243807724851 1.0 1.0 6 O00170,Q13620,P40818 3 +Narrow palpebral fissure 0.2450272920627189 0.164412430665796 0.8694064784775242 1.0 1.0 15 Q96HP0,Q9NXH9 2 +Omphalocele 0.2578376794608768 0.1634906519913152 0.8701321327584404 1.0 1.0 12 Q8TD19,Q14739,O75369,Q69YQ0,P36776,Q6DKJ4,P21333,Q8NCM8,P43034,O15111,P62258 11 +Pulmonary artery stenosis 0.2391508405681845 0.1609819406642054 0.872107624380436 1.0 1.0 16 P41227,P27635,Q15056,Q06124,Q15477 5 +Split nail 0.3461988304093574 0.1601722413743828 0.8727453952315316 1.0 1.0 5 P18074,O60832,P19447,P26639 4 +Abnormal pleura morphology 0.2264296956646535 0.1600643878557054 0.8728303537999689 1.0 1.0 24 Q02750,O95163,Q9UID3,Q06124,Q9UPY3,Q13043,P14174,P51617,Q93063,P08236 10 +Immunologic hypersensitivity 0.2108920233388067 0.159925784104441 0.8729395371505626 1.0 1.0 30 P50851,Q9UID3,O14646,P37837 4 +Nuclear cataract 0.3199766013454103 0.1586404432871648 0.8739521631293403 1.0 1.0 6 Q9H444,Q99797,P08670,Q03426,P51570 5 +Cerebral visual impairment 0.1969881257680893 0.1533253999587358 0.8781416712226169 1.0 1.0 69 Q96F86,Q01105,P30153,Q96C86,P49591,Q12873,Q9UP83,Q9UID3,P15311,Q9H490,Q9UBB6,Q15042,P03886,Q05639,Q9HD42 15 +Bradykinesia 0.2173380208375405 0.1517927758406701 0.879350380152957 1.0 1.0 27 Q99497,Q6DKK2,Q96RL7,P35270,Q14203,P06753,P42858 7 +Abnormal hair whorl 0.2259946658967145 0.1515711014260313 0.8795252277367611 1.0 1.0 23 P30153,Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 7 +Morning glory anomaly 0.4503214494447538 0.1510719198894133 0.8799189829255172 1.0 1.0 3 O00429,P26367 2 +Macrodontia 0.2272920401394778 0.1494842830676407 0.8811715103203062 1.0 1.0 22 Q9NXH9,O00232,Q9UID3,Q9Y296,Q96PZ0,Q7Z6Z7,P42858 7 +Hodgkin lymphoma 0.2587648235064551 0.1485112082570491 0.8819393411310978 1.0 1.0 11 P42771,Q6PD74 2 +Increased total bilirubin 0.3587751756161839 0.147592516711629 0.8826643612179237 1.0 1.0 4 P08237,Q9UGP8 2 +Epicanthus 0.2055382207398315 0.1475566719200546 0.8826926514839697 1.0 1.0 174 Q9NVI1,P54577,O95155,P46783,P36507,Q9UID3,Q06124,Q9UBM7,P63241,Q02750,P62847,Q15645,Q15056,Q15125,O96028,P07437,O43924,Q05639,P62899,P39019,Q12873,Q6DKJ4,O00203,Q9H490,Q4J6C6,Q9UBB6,Q7Z6Z7,P46821,P62081,Q15555,Q9BXW9,P41227,Q15392,Q9Y223,P43034,Q96PZ0,P62266,Q9NPF4,A2RRP1,O60701,P08708,Q8N0X7 42 +Skull asymmetry 0.4551562956471007 0.1467124323211719 0.8833590052230709 1.0 1.0 2 Q96DX4 1 +Paranoia 0.3145215896742761 0.1463700426809442 0.8836292750618726 1.0 1.0 6 Q96RL7 1 +Pulmonary cyst 0.3390290345269793 0.1455941803732934 0.88424176241865 1.0 1.0 5 Q86TI2 1 +Abnormality of the musculature of the upper limbs 0.2006970993343134 0.1443410297577841 0.8852311804583815 1.0 1.0 77 P62081,P08397,P62899,P62847,Q8NCE2,Q9Y223,P04792,Q06124,P08708,P07196,Q14203,Q96IJ6,Q8TD16,P46976 14 +Zonular cataract 0.2508115687768525 0.1441973592399175 0.8853446261748874 1.0 1.0 12 Q01968,Q9H6K4,Q15436 3 +Memory impairment 0.200818367010974 0.144065572054334 0.8854486905915171 1.0 1.0 38 P49770,P08397,Q14232,Q9NR50,P54277,Q9Y223,P03886,P42858 8 +Open bite 0.2383513215322711 0.1434534928558676 0.8859320386025213 1.0 1.0 15 Q6DKJ4,Q15056 2 +Furrowed tongue 0.2764376610092919 0.1413691616190417 0.8875783150364809 1.0 1.0 8 Q15437 1 +Chronic hemolytic anemia 0.4516505988898761 0.1413202438841606 0.8876169577986692 1.0 1.0 2 P60174 1 +Decreased mean corpuscular volume 0.4516505988898701 0.1413202438841519 0.8876169577986761 1.0 1.0 2 Q86SX6 1 +Abnormality of the cervical spine 0.201954958870709 0.140271748576872 0.8884452849783426 1.0 1.0 113 Q9NVI1,P83436,P62081,P62899,Q15555,P15586,Q02750,P37837,Q6DKJ4,Q9UP83,Q96EK5,Q15125,Q9UBM7,P08708,P78318,O95831 16 +Deep palmar crease 0.2455128913271755 0.1401373567988087 0.8885514653470277 1.0 1.0 13 P36507,O00170,Q02750 3 +Unusual infection by anatomical site 0.2302985870539982 0.139312228356233 0.8892034272784921 1.0 1.0 18 P98170 1 +Temporal optic disc pallor 0.4501898919076966 0.1391241630641969 0.8893520345394466 1.0 1.0 2 O00429 1 +Aplasia hypoplasia of the ear 0.1968384543708146 0.1386459112965373 0.88972996167564 1.0 1.0 58 P46821,P62081,P62899,O95155,Q15555,P08708,O96028,Q16512 8 +Diaphragmatic eventration 0.4420413170765872 0.1383207905151989 0.8899868949894727 1.0 1.0 3 P38935 1 +Corneal erosion 0.3535300253374637 0.1381603085375954 0.8901137233992433 1.0 1.0 4 Q96EK5 1 +Bifid uvula 0.199087583941504 0.1369580283089191 0.8910639709677943 1.0 1.0 39 O43505,Q15813,Q15392,P78318 4 +Overhanging nasal tip 0.4410912276818729 0.1369134606225433 0.8910991989960819 1.0 1.0 3 P17612 1 +Abnormally ossified vertebrae 0.3525285004384723 0.1364096024507988 0.8914974829779279 1.0 1.0 4 O15357,Q14739,Q8NCM8 3 +Cubitus valgus 0.2291055588848191 0.1355676149154932 0.8921631085963446 1.0 1.0 18 Q99575,P36507,Q06124,Q02750 4 +Triangular mouth 0.2915608483759899 0.1352094929574755 0.892446241724653 1.0 1.0 7 P18074,Q6DKJ4 2 +Thin eyebrow 0.2308324264089126 0.1342642857294924 0.8931935933480657 1.0 1.0 16 Q96EK5,Q15125 2 +Abnormal soft palate morphology 0.1973294956742595 0.1330238767517894 0.8941744973908967 1.0 1.0 74 Q9NVI1,O43505,P62081,P62899,P62847,Q15813,Q15392,Q6DKJ4,Q15436,P08708,P78318 11 +Short palm 0.2186111146932362 0.1328470075453252 0.8943143771574202 1.0 1.0 24 Q15813,Q15555,P46109 3 +Annular pancreas 0.3316204875675039 0.1314727626767859 0.8954013317631049 1.0 1.0 5 Q9Y4R8,O95155 2 +Abnormality of the intrinsic pathway 0.2521745120722201 0.1312899914908713 0.8955459088925843 1.0 1.0 11 Q06124,Q02750,P34949 3 +Restless legs 0.3477114855441223 0.1282141891658845 0.8979794714172011 1.0 1.0 4 P07196 1 +Flat acetabular roof 0.347559193218359 0.1279611504624123 0.8981797176702346 1.0 1.0 4 Q9NR45,O75369,O15357 3 +Right aortic arch with mirror image branching 0.4402570844288679 0.1249733513724 0.9005446474371286 1.0 1.0 2 Q8WYQ5 1 +Double aortic arch 0.4402570844288679 0.1249733513724 0.9005446474371286 1.0 1.0 2 Q8WYQ5 1 +Unilateral primary pulmonary dysgenesis 0.4402570844288679 0.1249733513724 0.9005446474371286 1.0 1.0 2 Q8WYQ5 1 +Germ cell neoplasia 0.2427909349553827 0.1239911442593513 0.9013222868120248 1.0 1.0 12 P42771,Q9UPY3 2 +Abnormality of humoral immunity 0.1928566472991904 0.1236702493304839 0.9015763683846538 1.0 1.0 63 P11586,P26038,P98170,P42345,P28070,Q13043,Q96J02,P51617,Q15477,P50851,Q6PGP7,P14174,P51570,P17812,P18074,Q13546,Q9Y5L0,O95999,Q9UJW0,P21266,P13051 21 +Pierre robin sequence 0.2861322410766498 0.1231581691602226 0.901981849498867 1.0 1.0 7 P38919,P36871,O75179,P98175,Q96DF8,Q8WYQ5 6 +Knee flexion contracture 0.2014283731204222 0.1222894236610361 0.9026698078275694 1.0 1.0 30 Q96AY3,Q8TD16 2 +Fetal onset 0.2847968562184954 0.1202947165521935 0.9042496893016604 1.0 1.0 7 Q7L590,P27635,Q9Y285 3 +Deep philtrum 0.2228601387213845 0.1168898814367773 0.9069473166278684 1.0 1.0 18 Q01968,P37837 2 +Abnormal conjunctiva morphology 0.2071392258727444 0.1155224027622272 0.9080310645127816 1.0 1.0 27 P28070 1 +Antiphospholipid antibody positivity 0.3394054582857649 0.1149533473083895 0.9084821002777824 1.0 1.0 4 P42224,P51617 2 +Slender long bone 0.22800392696801 0.1141030107194878 0.9091561356049768 1.0 1.0 15 Q15813,Q4G0J3,Q96J02 3 +Pseudobulbar signs 0.2449638113526686 0.1138937290906286 0.9093220366809384 1.0 1.0 11 P42356,P08397 2 +Response to drugs acting on neuromuscular transmission 0.3379128909675485 0.112686443087312 0.9102791496337416 1.0 1.0 4 Q06210,O75340,Q9Y5P6 3 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.3379128909675485 0.112686443087312 0.9102791496337416 1.0 1.0 4 Q06210,O75340,Q9Y5P6 3 +Impaired tandem gait 0.2196073194236051 0.1111709855279199 0.9114807591805568 1.0 1.0 19 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 6 +Myeloproliferative disorder 0.4294478527607479 0.1110954640592313 0.9115406456335772 1.0 1.0 2 P11274 1 +Impaired antigen specific response 0.2637612184925051 0.1110635449896872 0.9115659567312232 1.0 1.0 8 P50851,P17812 2 +Limb girdle muscle weakness 0.2027551646869382 0.1087648152866151 0.9133890315450236 1.0 1.0 28 Q8TD16,Q13126 2 +Reduced forced vital capacity 0.3181859554885335 0.1083037870907307 0.913754718624978 1.0 1.0 5 O95817 1 +Abnormal nipple morphology 0.1914052601811813 0.1080142877483598 0.913984358536641 1.0 1.0 58 P83436,Q15555,Q9Y223,Q96EK5,Q06124,Q14738,Q9UBM7,O96028 8 +Elevated circulating parathyroid hormone level 0.4193454120397376 0.1077921139906427 0.9141605985649446 1.0 1.0 3 P21359,P10644 2 +Decreased fertility in females 0.261566063926294 0.1062290175489211 0.9154006485243118 1.0 1.0 8 Q15645,Q86Y56 2 +Polymicrogyria 0.1984380624969573 0.1061828442503621 0.9154372822936718 1.0 1.0 85 P46821,Q96F86,Q01105,P42356,O43505,Q9BVA1,Q9UN37,Q96C86,P49591,Q96HP0,Q15392,O43379,Q96EK5,Q9UBB6,P07437,Q8TD16,Q05639,O95721 18 +Inflammatory abnormality of the eye 0.1909139953084902 0.1042227046843071 0.9169926163581784 1.0 1.0 42 P50851,P04080,O95999,P28070,Q13043,P14174 6 +Hypoplasia of teeth 0.2125654598776516 0.1040651605337409 0.9171176385688662 1.0 1.0 22 P04080,Q13535,Q01968 3 +Broad based gait 0.2092270301220251 0.1039993010761474 0.9171699032241708 1.0 1.0 24 P46821,P49589,Q12873,P61981,O14773,Q8IYU2,P42858 7 +Recurrent mycobacterial infections 0.4149963896027929 0.1026645808804223 0.9182291854227352 1.0 1.0 3 Q86Y56 1 +Caesarian section 0.3308973984215116 0.1024998364717106 0.9183599426433826 1.0 1.0 4 O14802,O60313,P33991 3 +Dark urine 0.414849513770495 0.1024953697872273 0.9183634878703236 1.0 1.0 3 P08397 1 +Abnormality of the antitragus 0.3297281496638404 0.1008766126740981 0.9196484087697204 1.0 1.0 4 O94766,Q9H2M9,Q8IY17 3 +Absent hypoplastic paranasal sinuses 0.4132086499123248 0.1006224402232704 0.9198501823921768 1.0 1.0 3 P04066,P10644 2 +Submucous cleft of soft and hard palate 0.2031237785549566 0.0967051251244263 0.9229605696497358 1.0 1.0 26 O43505,Q02750,Q15392,P36507,Q14738,P62266 6 +Parietal cortical atrophy 0.4160093485246947 0.0959717007779184 0.923543048299555 1.0 1.0 2 Q6P3W7 1 +Flat face 0.2000578755364427 0.093591374921299 0.9254337613556812 1.0 1.0 27 Q96C86,Q15125 2 +Upper limb amyotrophy 0.2152431911247464 0.0935372035976235 0.9254767950412393 1.0 1.0 17 P04792,P07196,Q14203 3 +Abnormal esophagus physiology 0.2273515671081673 0.0929964271373575 0.9259063996546628 1.0 1.0 233 Q9GZZ9,P48735,O95155,O75874,Q99720,P15586,Q9UBM7,Q96J02,Q96IJ6,P03886,Q01105,P42356,Q15056,P07737,O96028,P42858,Q96PU5,Q86TI2,O00203,Q9HD42,Q96RL7,O75306,Q8N0X7 23 +Abnormal c reactive protein level 0.3075936360301963 0.0922261262774924 0.9265183807329412 1.0 1.0 5 P14174 1 +Generalized hyperpigmentation 0.2188065947576095 0.0912283998111556 0.927311109253142 1.0 1.0 15 P36507,Q02750,P40818,Q96IJ6 4 +Localized skin lesion 0.2254939098741233 0.0907719312864649 0.9276738135424034 1.0 1.0 229 P48735,Q9NVI1,P34913,O75874,O95155,P42771,Q96AY3,Q9H4L7,Q15645,Q9NYB0,Q96HP0,Q6PD74,Q13126,Q15056,Q15125,O96028,P42858,Q96PU5,Q15437,Q6DKJ4,Q01968,Q15555,Q15392 23 +Syndactyly 0.198247125446293 0.0906110238950539 0.9278016721678845 1.0 1.0 101 Q9NVI1,Q9UBC2,Q9H4L7,P46109,Q96HP0,Q6DKJ4,Q96EK5,Q15125,Q9UBM7,O43924,Q96PU5 11 +Enamel hypoplasia 0.2216633960094934 0.0903114051855919 0.9280397571614656 1.0 1.0 14 Q13535 1 +Shoulder girdle muscle weakness 0.2178459442178141 0.0890126114098066 0.9290718874510856 1.0 1.0 15 Q9Y223,P06753,Q8TD16,O75190,P46976 5 +Erythroid hyperplasia 0.3203741596024559 0.0886448750874653 0.929364143277022 1.0 1.0 4 P06132,Q9Y606,Q86SX6 3 +Celiac disease 0.3186928149803785 0.0865864684766248 0.9310002220926256 1.0 1.0 4 Q13043 1 +Abnormal incisor morphology 0.2072851153981009 0.0861898065901122 0.9313155337165951 1.0 1.0 21 Q9NXH9,O00232,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 6 +T cell lymphoma 0.300981753900613 0.0831473893547072 0.933734345017176 1.0 1.0 5 Q07864,P52701 2 +Eeg with multifocal slow activity 0.2302284710017615 0.0830222366718215 0.9338338583425584 1.0 1.0 11 Q9GZZ9,P38606,Q96F07,Q00610,Q86SQ9,Q96E22,P61981,P49588,O95319,Q05639 10 +Abnormal oral frenulum morphology 0.2091134776752478 0.0812451766145684 0.9352469724973193 1.0 1.0 18 O43924,P46109 2 +Sleep apnea 0.1955687603584254 0.0810552471838364 0.9353980160998152 1.0 1.0 27 P48444,P51114,Q9Y223,Q9UID3,O00170,Q14203,Q4G0J3,P60891 8 +Premature loss of teeth 0.2192918475837629 0.0798373159699269 0.93636664518336 1.0 1.0 13 P04080,Q15436 2 +Exaggerated cupid s bow 0.2627567743387612 0.078771209248072 0.9372146045613126 1.0 1.0 7 P61978,Q6DKJ4,P11233 3 +Abnormality of the supraorbital ridges 0.1977298246628117 0.077700386279057 0.938066386830516 1.0 1.0 25 Q02750,P40855,Q9UPP1,P36507,Q9HCK8,Q15436,P17980,Q8IWS0 8 +Abnormal pulmonary valve morphology 0.2085250310470933 0.0775503520721495 0.9381857366823808 1.0 1.0 17 Q96HP0,Q6DKJ4 2 +Abnormality of corneal thickness 0.2077378256432474 0.0757897858315867 0.939586342477919 1.0 1.0 17 Q15051 1 +Systemic lupus erythematosus 0.2608279071299973 0.0756454552040461 0.9397011720169924 1.0 1.0 7 P49327,P00491,P51617 3 +Regional abnormality of skin 0.1827272939580256 0.0755112008135 0.9398079860210308 1.0 1.0 147 Q9NXH9,Q9UID3,Q9UBM7,Q96J02,Q96IJ6,Q96AY3,Q9H4L7,Q02750,Q9H4A3,Q96HP0,Q6PD74,Q15056,Q13535,O96028,O95721,P42858,Q15437,Q6DKJ4,O95817,P46821 20 +Fatty replacement of skeletal muscle 0.239638399835524 0.0753882535670358 0.9399058049091944 1.0 1.0 9 P51114 1 +Lymphedema 0.208165458812775 0.0747695618347065 0.9403980601429532 1.0 1.0 16 Q02750,Q14739,P36507,Q06124,P26358,P08236,Q00535 7 +Lactose intolerance 0.3845704266510737 0.0728906428065267 0.9418931400957123 1.0 1.0 3 P42345,O95394 2 +Striae distensae 0.2313119885068407 0.0724771439749185 0.9422221940904144 1.0 1.0 10 P53618,Q13620,P40818,O00170,P17612 5 +Hereditary nonpolyposis colorectal carcinoma 0.2429742652235353 0.0701450822218335 0.9440781846229652 1.0 1.0 8 O60566,O14965,P52701,Q9Y620 4 +Premature birth 0.182261610271323 0.0698014658161725 0.9443516804730234 1.0 1.0 49 P54577,Q02750,P46109,Q9UNF1,P27635,P39019,P36507,Q96HP0,Q9UBM7,P38935,P06753,Q9NPF4,P51570 13 +Mild short stature 0.3796025715955592 0.0689822691919282 0.94500373301033 1.0 1.0 3 Q14739,P10644 2 +Asthma 0.2015192720571799 0.0670639900779269 0.9465307610841124 1.0 1.0 19 Q9UID3,P37837 2 +Hypoplasia of the musculature 0.2859649122807038 0.0651609048862563 0.9480458883261856 1.0 1.0 5 Q9Y487,Q9Y5S9,Q9NR77,P06753 4 +Limitation of knee mobility 0.2859649122807014 0.0651609048862538 0.9480458883261876 1.0 1.0 5 P55072,Q93063,Q14315,Q9BPU6 4 +Aplasia hypoplasia of the abdominal wall musculature 0.297573808827822 0.064207461120898 0.9488050365404912 1.0 1.0 4 O75369,Q06124,P22681 3 +Parakeratosis 0.2845029239766123 0.0635984676754895 0.9492899518917955 1.0 1.0 5 P15924,P53602,P00338,Q03426 4 +Poikilocytosis 0.2098475967174624 0.0633419315131769 0.949494226263566 1.0 1.0 13 P27797,P11171,P11172,Q02241,Q05682,Q96RL7,P41440,Q9Y6B6,P27708,Q8NBF2,O60488,P11413 12 +Aplasia hypoplasia of the optic nerve 0.1899262089833261 0.0629909862997799 0.9497736819587752 1.0 1.0 26 Q9NVI1,P30153,P36507,P07196,O95721 5 +Intellectual disability borderline 0.3742331288343576 0.0624810931337345 0.9501797180119806 1.0 1.0 2 Q7Z392 1 +Frontotemporal cerebral atrophy 0.3667445938047921 0.0599967699498527 0.9521582072643784 1.0 1.0 3 Q9H9E3,Q99714 2 +Lower extremity joint dislocation 0.1884838045447318 0.0599233939808857 0.9522166476698528 1.0 1.0 80 Q9NVI1,Q15056,Q13535,Q15125,Q9UBM7,O96028,Q01968,Q8TD16,Q96PU5 9 +Myopathic facies 0.2629423808130964 0.0592315057570795 0.95276771572164 1.0 1.0 6 P22314,Q9Y5P6,Q969X5,Q00577,P06753 5 +Increased skull ossification 0.3666374525270249 0.0582988528012397 0.9535105812947496 1.0 1.0 2 P54802 1 +Decreased testicular size 0.1895881133963588 0.0568590497609428 0.9546574750667818 1.0 1.0 24 Q9UPP1 1 +Wide anterior fontanel 0.1880912042261397 0.0561706424282855 0.955205868174583 1.0 1.0 25 Q14738,Q15125,Q15436,P37837 4 +Lumbar scoliosis 0.2864659456299271 0.0548654515183658 0.9562456560963966 1.0 1.0 4 P27635,P21281,O95352 3 +Increased blood urea nitrogen 0.3580114278911012 0.0547664472352486 0.9563245314943174 1.0 1.0 3 O95163 1 +Depressed nasal tip 0.2858813212510929 0.0544168908635148 0.9566030218302368 1.0 1.0 4 Q93063,Q96KP1,Q01082 3 +Aplasia hypoplasia affecting the fundus 0.1765184504596137 0.0539302516529256 0.9569907343968728 1.0 1.0 31 Q9NVI1,P30153,Q86YV9,P36507,P07196,O95721 6 +Branchial anomaly 0.2326992934578375 0.053846930131878 0.9570571188924366 1.0 1.0 8 P27635,P11274,P46109 3 +Abnormal pons morphology 0.1839802129447424 0.0534465314845233 0.9573761314042596 1.0 1.0 27 Q9UN37,Q9BVA1,P30153,P36405,Q9UID3,Q99986 6 +Microvesicular hepatic steatosis 0.2195553096343476 0.0532760082123718 0.957511995720708 1.0 1.0 10 Q00059,P54577,Q9UN37 3 +Absent or minimally ossified vertebral bodies 0.3524254821741666 0.0517651979845871 0.9587157863396742 1.0 1.0 3 Q14739,Q8NCM8 2 +Bell shaped thorax 0.3524254821741616 0.0517651979845846 0.9587157863396762 1.0 1.0 3 O15357,Q96HY6 2 +Knee dislocation 0.3523225241016628 0.0517346432906612 0.9587401328357614 1.0 1.0 2 O94766 1 +Severe short limb dwarfism 0.3523225241016627 0.051734643290661 0.9587401328357616 1.0 1.0 2 Q14739 1 +Primary hypercortisolism 0.3515488018702504 0.0513174905081033 0.959072531057122 1.0 1.0 3 P17612,P10644 2 +Adrenocortical abnormality 0.3515488018702504 0.0513174905081033 0.959072531057122 1.0 1.0 3 P17612,P10644 2 +Breast hypoplasia 0.2797427652733051 0.0499554980390115 0.96015785143374 1.0 1.0 4 P98172,Q9Y619,Q93008 3 +Limited wrist movement 0.2532417268747948 0.0484043120492838 0.961394022816758 1.0 1.0 6 Q9Y223 1 +Abnormal aortic morphology 0.1880355994471531 0.0479201207729674 0.9617799037526762 1.0 1.0 116 Q9NVI1,O95155,P30153,Q9NXH9,Q06124,Q9UBM7,Q02750,P62847,Q15645,Q9Y3Z3,Q15056,Q9Y296,P42858,Q96PU5,P62899,P46109,P37837,Q6DKJ4,P46821,P62081,P08708 21 +Capillary malformation 0.1963209014419155 0.0476850520909739 0.9619672472538852 1.0 1.0 15 Q6DKJ4,Q15056 2 +Enlarged thorax 0.1922229582277089 0.0474430842834462 0.9621600913682968 1.0 1.0 18 Q02750,Q14739,P41227,Q06124,Q99575,P17612,P08236 7 +Downslanted palpebral fissures 0.1798227188680042 0.0471495602667102 0.9623940278510736 1.0 1.0 148 Q9GZZ9,P30153,Q9NXH9,Q06124,Q9UBM7,P63241,Q02750,Q15645,Q14738,Q15125,Q13535,Q96EK5,Q9Y296,O96028,A1X283,O14646,P78318,Q05639,P42858,O95721,Q6DKJ4,Q15555,P41227,Q15392,Q9NPF4,Q8N0X7 26 +Nephrocalcinosis 0.183997996593392 0.0452619029627021 0.963898553331259 1.0 1.0 23 Q15056,P16930 2 +Abnormality of lower limb metaphyses 0.2372732592159161 0.0437396244352107 0.9651119536942558 1.0 1.0 7 Q9NUQ7,P06400,P61011,Q9Y3A5,O96017,O95831 6 +Nonketotic hypoglycemia 0.26198830409357 0.0434514943633167 0.9653416298674488 1.0 1.0 5 P35914,P23786,P49748,P31751 4 +Hypoplasia of the brainstem 0.1719268676357702 0.0433423189083093 0.9654286572897766 1.0 1.0 31 O43505,Q9UPT5,Q13409,Q96EK5,P43034,P07437,Q7Z460,Q9HD42 8 +Prominent antitragus 0.3296317942723555 0.0420027727430405 0.9664964877401504 1.0 1.0 3 O94766,Q9H2M9 2 +Abnormal scapula morphology 0.1764508506251541 0.0415102095551443 0.9668891538225776 1.0 1.0 54 Q14739,P46783,Q06124,O15357,P46777,Q93063,P62847,Q06210,Q9UHD8,P06753,Q8TD16,Q13642,P62899,Q9Y2W2,Q9Y5P6,P39019,Q9Y5L0,P62081,Q9Y223,P07196,P08708 21 +Broad chin 0.3166812737364868 0.0414068872474478 0.9669715222782986 1.0 1.0 2 Q9H5V9 1 +Abnormal uvea morphology 0.1895836402150734 0.041232965755388 0.9671101731390694 1.0 1.0 107 Q9NVI1,Q9UBC2,O95155,Q9UBM7,Q13043,Q96IJ6,P50851,Q15645,Q15056,Q96EK5,O96028,P14174,P78318,O43505,O00203,Q01968,O14617,O95999,P41227 19 +Curly hair 0.192591964324284 0.0399204315699705 0.9681565620482416 1.0 1.0 12 P42345,Q02750,Q93008 3 +Recurrent sinopulmonary infections 0.2328847279110549 0.0390094277584987 0.9688828720719512 1.0 1.0 7 P02786,P61011,Q86Y56,P40763,O60934,Q9Y487 6 +Abnormal bowel sounds 0.3003213555360732 0.0387786800876125 0.9690668428722686 1.0 1.0 2 Q9UER7 1 +Protracted diarrhea 0.3003213555360732 0.0387786800876125 0.9690668428722686 1.0 1.0 2 Q9UER7 1 +Abnormal right ventricular function 0.3003213555360732 0.0387786800876125 0.9690668428722686 1.0 1.0 2 Q9UER7 1 +Hematemesis 0.3003213555360732 0.0387786800876125 0.9690668428722686 1.0 1.0 2 Q9UER7 1 +Zollinger ellison syndrome 0.3003213555360732 0.0387786800876125 0.9690668428722686 1.0 1.0 2 Q9UER7 1 +Reduced renal corticomedullary differentiation 0.2903885480572546 0.0376367554225378 0.9699773020824096 1.0 1.0 2 O60231 1 +Abnormal renal corticomedullary differentiation 0.2903885480572546 0.0376367554225378 0.9699773020824096 1.0 1.0 2 O60231 1 +Abnormal circulating long chain fatty acid concentration 0.2532163742690101 0.0374351620900619 0.9701380370161888 1.0 1.0 5 P40855,O75381,P23786,P50542 4 +Flat nasal alae 0.311805961426069 0.0367268172010069 0.9707028260291956 1.0 1.0 3 P18074,P19447 2 +Abnormality of amino acid metabolism 0.311805961426069 0.0367268172010069 0.9707028260291956 1.0 1.0 3 P18074,P19447 2 +Delayed eruption of primary teeth 0.3118059614260623 0.0367268172010053 0.970702826029197 1.0 1.0 3 Q13045,Q8NC56 2 +Enterocolitis 0.2699386503067412 0.0360781565300437 0.9712200395507078 1.0 1.0 2 P42224 1 +Brushfield spots 0.2531423560362392 0.0353604735839775 0.971792302497772 1.0 1.0 4 P40855,O75381,P50542 3 +Asthenia 0.2843366452367087 0.0316197984359124 0.9747752544147414 1.0 1.0 3 P11586,O00754 2 +Abnormality of the testis size 0.1659479277277205 0.0313167728485493 0.9750169141697274 1.0 1.0 31 Q9UPP1,O43505 2 +Abnormal foveal morphology 0.2403916566718439 0.0306781646399856 0.9755262050579996 1.0 1.0 4 Q86YV9 1 +Nasogastric tube feeding in infancy 0.2240750870864876 0.0305709751741359 0.9756116897819058 1.0 1.0 7 P06753,Q92734 2 +Down sloping shoulders 0.1697930619818154 0.0299955630117237 0.9760705917837188 1.0 1.0 28 P41227,Q9NXH9,Q15056,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 7 +Bronchiectasis 0.177814902499116 0.0297144622289831 0.9762947778243424 1.0 1.0 20 P50851,Q86Y56,Q86TI2 3 +Abnormal protein o linked glycosylation 0.2369130172065517 0.0296162809097661 0.976373080720876 1.0 1.0 4 Q8N511 1 +Irregular femoral epiphysis 0.2615429573348956 0.0293230850591307 0.976606915602124 1.0 1.0 3 P26373,P50542 2 +Acute lymphoblastic leukemia 0.1827197963011899 0.0292288920939151 0.9766820385145742 1.0 1.0 15 P42771 1 +Epicanthus inversus 0.2571595558153177 0.0290229931293299 0.9768462524514108 1.0 1.0 3 Q7Z6Z7,Q16531 2 +Alacrima 0.230239364130832 0.0288046462941223 0.9770203952121064 1.0 1.0 6 Q7Z392,Q96IJ6 2 +Generalized dystonia 0.2527761542957384 0.028759100942183 0.9770567200964166 1.0 1.0 3 P82663,P04350 2 +Hypoplasia of the ear cartilage 0.2342909795978661 0.0274425287836563 0.9781067779450888 1.0 1.0 5 Q9NPF4 1 +Small hand 0.1624618792021553 0.0266160792000526 0.978765948455916 1.0 1.0 33 Q15813,Q14320,P42858 3 +Adenomatous colonic polyposis 0.2234208042292497 0.0262486787941301 0.9790589891784268 1.0 1.0 4 Q07864 1 +Rheumatoid factor positive 0.2185274093964681 0.0252881479567391 0.9798251274699086 1.0 1.0 4 P49327,Q13546 2 +Abnormal sputum 0.2162083089525996 0.0241560417082665 0.9807281415234206 1.0 1.0 7 P49327,Q07617,P31153,P49815,Q86Y56,Q9NZ08 6 +Facial telangiectasia 0.2246934528045928 0.0237215197811603 0.9810747405315146 1.0 1.0 5 Q07864 1 +Pericarditis 0.2160818713450342 0.0210308773909979 0.9832210245227022 1.0 1.0 5 P14174,P49327,O15460,Q9NZ08 4 +Irregular hyperpigmentation 0.1766992232362088 0.020470236402763 0.9836682550096404 1.0 1.0 74 Q9NVI1,P42345,P36507,Q9NXH9,Q06124,Q15477,Q02750,Q9H4L7,Q15645,O00232,Q9Y296,P07437,A1X283,P42858,Q15437,Q7Z6Z7,Q15555,Q9BXW9,Q96PZ0,Q15436 20 +Abnormal circulating bilirubin concentration 0.1640159241625962 0.0198951635256338 0.984127003330216 1.0 1.0 26 Q9Y5L0,P00390,Q14739,Q9H267,P40855,P08237,P55263,P43034,P23786,Q9NSD9,Q9UGP8 11 +Narrow forehead 0.1684459783935708 0.0192360886598086 0.9846527683358954 1.0 1.0 51 P83436,P41227,P36507,Q14738,Q9Y296,Q9H490,Q9UBM7,A2RRP1,Q9NPF4,Q15042 10 +Abnormal neutrophil count 0.1726517110908159 0.0191241837573322 0.9847420391079428 1.0 1.0 69 P50851,Q9NVI1,P62081,P62899,P98170,O00203,Q96J02,P08708,O14617 9 +Abnormality of the scrotum 0.1682377565390443 0.0186369716397787 0.9851307088485984 1.0 1.0 51 Q15555,Q9NXH9,Q96EK5,Q9UBM7,P42858 5 +Disproportionate tall stature 0.1575540398509148 0.0175519208071273 0.9859963123984126 1.0 1.0 31 Q9NXH9,O96028,P42858 3 +Gynecomastia 0.1624082232011749 0.0137150104589592 0.9890573479595208 1.0 1.0 20 Q13620,Q9H7N4,Q8IWS0,Q06787,Q8WWQ0,P21912,A1X283,Q8IY17,Q8NI60,P51809,P31751,Q15437,Q9Y4W2,O00170,O14802,A6NHR9,Q01082,Q9NW13,Q8IY37 19 +Scaling skin 0.180846259580744 0.0132165843536833 0.989454998395352 1.0 1.0 10 P50851,P20810,Q9Y3Z3 3 +Oral cleft 0.1878572900482229 0.0114567860321642 0.9908590072802734 1.0 1.0 171 Q9NVI1,Q9UBM7,Q14320,Q02750,Q15645,Q15813,Q13535,Q15125,Q96EK5,O96028,O43924,P78318,Q96PU5,O43505,P62899,P46109,Q6DKJ4,P62081,Q15555,Q9UPP1,Q15392,Q15436,P08708 23 +Tube feeding 0.1713717237953663 0.0107662357935299 0.9914099526307228 1.0 1.0 70 Q96F86,Q01105,P30153,Q99720,Q96C86,Q9UBB6,P49591,Q9UP83,P15311,Q9H490,Q96J02,P06753,Q05639 13 +Broad thumb 0.1518707106029684 0.0101035421609569 0.9919386768526643 1.0 1.0 31 Q6DKJ4,Q9NXH9,O00232,Q93008,Q96PZ0,Q9Y296,Q7Z6Z7,P42858 8 +Olivopontocerebellar hypoplasia 0.1833869552500645 0.0091497446009671 0.992699661909147 1.0 1.0 6 Q9Y5P6,Q96GM8,P30153,Q9UNW1,Q99700 5 +Increased head circumference 0.1727430370487303 0.008043404220807 0.9935823611556324 1.0 1.0 131 Q9NXH9,Q12955,Q9UPY3,Q96J02,Q16512,Q02750,Q96HP0,Q9H9P8,O14646,Q8TD16,P78318,P42858,O43505,Q15437,Q12873,Q6DKJ4,Q8NCE2,P49770,Q15392,Q15436 20 +Leukemia 0.1675647148273008 0.0078857773233958 0.9937081252343468 1.0 1.0 58 P62081,Q02750,P62899,Q9BXW9,P62847,Q15645,P39019,Q9Y3Z3,P42771,Q06124,P08708 11 +Abnormal platelet volume 0.1850946745263953 0.0076947662430275 0.9938605254015572 1.0 1.0 8 Q6PGP7,Q14739,P12814,P35579,Q15477 5 +Fatigable weakness of skeletal muscles 0.1835480093676808 0.0070548214076642 0.9943711136117284 1.0 1.0 9 Q9Y5P6,Q96GM8,P11310,Q9Y281,Q92734,Q9UNW1,Q14315,P06753 8 +Abnormal corneal epithelium morphology 0.1551334173853945 0.0061509733292769 0.9950922642936116 1.0 1.0 18 P18074,P49327,Q14739,O95163,P26639,P50747,Q96EK5 7 +Autoimmune thrombocytopenia 0.1816065857247022 0.0058440267502542 0.9953371678244132 1.0 1.0 9 P50851,P42224,P49327,P00491 4 +Scapular winging 0.1479139286674353 0.0055431796946571 0.9955772051536412 1.0 1.0 26 Q06124,Q8TD16,P07196,Q9Y223 4 +Hypoplasia of the pons 0.1335274883240909 0.0018251602648507 0.9985437336122064 1.0 1.0 23 Q9BVA1,P30153,Q9UID3,P08243,Q99986 5 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1480ba8043a3f43082d4fa1ca15d39aff4f2d20a --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Discoid lupus rash", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hippocampal atrophy", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal stem cell deficiency", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lupus anticoagulant", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microangiopathic hemolytic anemia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocerebellar cyst", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small forehead", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary cusp", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supernumerary vertebrae", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT2", "AKT3", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "ATRX", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCKDHA", "BCKDK", "BCL10", "BCOR", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBL", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD109", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG4", "COG5", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAH", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H2AFY", "HACE1", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIRA", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKB", "IMPDH1", "INF2", "INPPL1", "INTS1", "INTS8", "IQCB1", "IRAK1", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5B", "KDM5C", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "L2HGDH", "LAMC1", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LUZP1", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAPK1", "MAPRE2", "MARK3", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED23", "MED25", "MESD", "MFF", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCOS", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPDZ", "MPG", "MPI", "MPP5", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MVK", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NACC1", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK1", "NEK9", "NEMF", "NF1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NR3C1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUS1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PAX6", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD54B", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RSPRY1", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SBF1", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC33A1", "SLC39A14", "SLC5A6", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPAG1", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SURF1", "SUZ12", "SVIL", "SYNE2", "TAF15", "TAF2", "TAF6", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D8B", "TBCD", "TBCE", "TBL2", "TCF20", "TCOF1", "TCTN3", "TDRD7", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKT", "TLK2", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC2L", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRRAP", "TSC2", "TSFM", "TSPYL1", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "UBA1", "UBA5", "UBAC2", "UBE3A", "UBE4A", "UBE4B", "UBR7", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", 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b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 17.756906077348066 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..42544143bd63a645116e5969628e2bd7de0e47fe --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..773508c5acbce88b12c6fc8952cf7690ac2a0060 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,90 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome 0.6979779814907469 4.043048003184358 5.2760813482155555e-05 0.009504503130383 0.0047748536201351 33 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 25 +Ribosome 0.4635917679042206 3.111848119522159 0.0018592012435798 0.2859688129924476 0.0350615648672456 72 P46778,P46783,P05386,P27635,P62917,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62861,P08865,P62241,P84098,P62899,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P26373 35 +Glutathione metabolism 0.7004316083318682 3.09970984740015 0.0019371030313395 0.2959850429040445 0.0350615648672456 21 P48735,P28161,O75874 3 +Folate biosynthesis 0.8472090855948409 2.1414947189665168 0.0322341639036969 0.9973428144359344 0.2079133174969945 5 P00374 1 +Peroxisome 0.4374691131268826 2.1135650532862966 0.0345524333026752 0.9982785543924244 0.2079133174969945 37 P48735,P34913,O75874 3 +Metabolism of xenobiotics by cytochrome p450 0.6424062809479647 1.8563929020896923 0.0633975757056584 0.999992895962578 0.3224467955243341 8 P28161 1 +Pentose phosphate pathway 0.5411114443949429 1.835887827723256 0.0663742483015155 0.9999960071701584 0.3224467955243341 15 P06744,Q96G03,P36871,P08237,P37837,P29401,O95336,Q01813,P11908,P60891 10 +Nucleotide excision repair 0.4709476408859281 1.8095710546707808 0.0703623320283248 0.99999816015187 0.3224467955243341 25 P18074,Q07864,P56282,P35251,P41208,P12004,P35244,P54727,P40938,P40937,P15927,P54725,P28340,P27694,P18858 15 +Mismatch repair 0.5071453972659299 1.805023976681672 0.0710709301560055 0.9999983973368506 0.3224467955243341 19 P35251,P52701,Q9UQ84,P12004,P35244,Q04837,P40938,P40937,P15927,P28340,P18858 11 +T cell receptor signaling pathway 0.4844749001401514 1.8038236292335068 0.0712589603368694 0.9999984549972428 0.3224467955243341 23 Q16539,Q02750,O95999,P31751,P49841,P36507,Q9UHD1,Q16512,O00221 9 +Bladder cancer 0.6054977380679798 1.76962873852959 0.0767890081511128 0.9999994758266288 0.3268141902763432 9 O00716,P10398,Q02750,P42771 4 +Drug metabolism cytochrome p450 0.6658720070058743 1.768765657227488 0.0769329901445694 0.99999949041742 0.3268141902763432 7 P28161 1 +Dna replication 0.4253319265540506 1.7645409917819468 0.0776409402313964 0.9999995564901748 0.3268141902763432 30 P28340,Q07864,P56282,P35251,P49642,P12004,P35244,P49736,Q04837,P40938,P40937,P15927,P25205,P49643,P33991,P18858,P39748 17 +Starch and sucrose metabolism 0.5081868841674306 1.720756674019344 0.0852949874306121 0.9999999018542084 0.3284764409561872 16 P13807,P06744,P06737,Q96G03,P36871,Q8NBZ7,P35573,O60701,P08236,Q16851 10 +Erbb signaling pathway 0.4801945424856946 1.6597321905660338 0.0969683404670092 0.9999999904007176 0.352893399739106 20 Q02750,P46109,P31751,P49841,P36507,Q13177,P10398,P46108,Q16512 9 +Renal cell carcinoma 0.4812483000310653 1.6340011945721122 0.1022585997670226 0.999999996685814 0.352893399739106 19 Q02750,P46109,P31751,P36507,Q16512,P10398,Q06124,P46108,Q15370 9 +Citrate cycle tca cycle 0.4420093960543642 1.5965470785883529 0.1103667035781863 0.9999999993585006 0.3699328397713283 25 P48735 1 +Fructose and mannose metabolism 0.4723208373283057 1.5176244077277978 0.1291091102081136 0.9999999999864032 0.4045512194946093 17 P60174,Q13614,Q13630,Q9Y217,Q00796,Q9Y5P6,P34949,P08237,P04075,Q96IJ6,Q01813 11 +Tgf beta signaling pathway 0.5575470258025977 1.5155420200909844 0.1296351974071123 0.999999999987812 0.4045512194946093 9 P30154,P30153,O75116,Q7Z3T8,P63208,Q13464 6 +Leishmania infection 0.606425964795987 1.4807563781081043 0.1386715045405218 0.9999999999981568 0.4183257053639074 7 Q16539,P51617,P49006 3 +Chronic myeloid leukemia 0.4111174426281014 1.366569256029753 0.1717603592025924 0.9999999999999984 0.4797935438047456 25 Q00534,Q02750,P46109,P36507,O00716,P42771,Q06124,P10398,P46108 9 +Rig i like receptor signaling pathway 0.5268321176256149 1.350705553770053 0.1767897725205682 0.9999999999999994 0.4797935438047456 9 Q16539 1 +Vegf signaling pathway 0.4726305834855324 1.3402806756707033 0.1801541115895508 0.9999999999999998 0.4797935438047456 14 Q16539,Q02750,P36507,P04792,Q9UHD1 5 +Riboflavin metabolism 0.6055306108865436 1.299963987751568 0.1936133121967613 1.0 0.5006287072516258 6 Q9NPH0 1 +Glioma 0.4296296108539004 1.288232308213794 0.1976651086182967 1.0 0.5039068261959397 19 Q00534,Q02750,P31751,P36507,O00716,P42771,P10398,P0DP25 8 +Cysteine and methionine metabolism 0.4497514748930546 1.2715354800713086 0.203538213519097 1.0 0.5116724534299524 15 O43865,Q9NZL9,Q13126 3 +Pathways in cancer 0.3094568182559736 1.2585427334595674 0.2081955427053423 1.0 0.5162108661598214 62 P98170,P42345,P36507,O00716,P42771,Q13043,P24941,P46108,Q15370,Q00534,Q02750,P06753,P08238,P52701,P46109,P31751,P49841,Q92734,Q16204,P10398,Q13309,P11233,P07900 23 +Cell cycle 0.3115228750851344 1.2218159482492963 0.2217772361398666 1.0 0.5385561691963853 58 P12004,P49736,P33981,O00716,P42771,P61981,P24941,Q99640,P31946,Q00534,P63208,Q13535,Q9UBD5,Q14674,P33991,P49841,O60566,O43913,P78527,P63104,P62258,Q04917,O95067,P27348,P25205,Q13309,P06493 27 +Non small cell lung cancer 0.4252358595753037 1.210377472516858 0.2261340820935098 1.0 0.5385561691963853 17 Q00534,Q02750,P36507,O00716,P10398,P42771,Q13043 7 +Nod like receptor signaling pathway 0.4727048048148997 1.1563121548892012 0.2475534983607059 1.0 0.5819114701725685 11 Q16539 1 +Regulation of autophagy 0.487489708316917 1.138588679093448 0.2548747524629655 1.0 0.5856123981779369 9 Q9Y4P1,Q99570,Q8NEB9,Q13131,Q9NT62,P60520 6 +Nicotinate and nicotinamide metabolism 0.6105246153850286 1.1215128220856652 0.2620696367536623 1.0 0.5856123981779369 5 Q9BQG2 1 +Melanoma 0.4456804281306853 1.1133396266559243 0.2655625935804768 1.0 0.5861808468056867 13 Q00534,Q02750,P36507,O00716,P10398,P42771 6 +Gnrh signaling pathway 0.4304576136401694 1.0849229224980037 0.2779557945740674 1.0 0.606144564071159 14 Q16539,P0DP25,Q02750,P36507 4 +Ubiquitin mediated proteolysis 0.3035381084502464 1.061399398370805 0.2885084302206726 1.0 0.6159972196066513 51 Q93034,P49427,O95155,P98170,Q9UBE0,P46934,Q16763,Q9C0C9,P68036,Q13309,Q96J02,Q15386,Q7Z6Z7,Q15370,Q9UBT2,Q96PU5 16 +Steroid biosynthesis 0.4465531253339896 1.059701407569804 0.2892804622462175 1.0 0.6159972196066513 12 Q15125,Q9UBM7,Q16850 3 +Tyrosine metabolism 0.484557986569931 1.0406954817898282 0.2980169008418833 1.0 0.6200121730158723 8 Q7Z4G4,P17174,P16930 3 +P53 signaling pathway 0.4078096811481384 1.0101237291086684 0.3124360148588359 1.0 0.6320645443539382 15 Q00534,O95067,Q13535,P42771,P24941 5 +Hedgehog signaling pathway 0.6146279931534855 1.0062138320762994 0.314312719806999 1.0 0.6320645443539382 4 P49841,P48729 2 +Selenoamino acid metabolism 0.4611083293428046 0.996860967005224 0.3188320003004106 1.0 0.6320645443539382 9 O43865,Q9NZL9 2 +Thyroid cancer 0.4605661973704394 0.9939614074226168 0.3202416564170345 1.0 0.6320645443539382 9 P36507,Q02750,Q16204,P06753 4 +Vasopressin regulated water reabsorption 0.3829827911247083 0.9357386163557816 0.3494077829723758 1.0 0.6695044715786571 17 Q9UJW0,Q13409,Q14203,Q9Y6G9,O43237 5 +Toll like receptor signaling pathway 0.3937690434141385 0.9235378554272546 0.3557269822362969 1.0 0.6706935810913516 15 Q16539,Q02750,P36507,P51617,Q13546 5 +B cell receptor signaling pathway 0.3905263890627991 0.9036639072765258 0.3661736429353657 1.0 0.6763002997071551 15 Q02750,O95999,P49841,P36507,Q9UHD1,O00221 6 +Phenylalanine metabolism 0.5835353833871519 0.8773172794237027 0.3803143293354887 1.0 0.6953221576739742 4 P30041,P17174 2 +Glycerophospholipid metabolism 0.3658446328404909 0.8435462081803556 0.3989230341212235 1.0 0.7220506917594146 18 P35790 1 +Natural killer cell mediated cytotoxicity 0.3697222918194847 0.8351397629573821 0.4036390207793749 1.0 0.7233530966442264 16 Q02750,P10398,Q06124,Q9UHD1,Q16512 5 +Oocyte meiosis 0.2820914762772483 0.8004002495279977 0.4234789364813021 1.0 0.7421709309787347 45 Q02750,P30154,P30153,P0DP25,P63208,Q04917,O95067,Q14738,P27348,Q14674,O14965,P24941,Q9UHD1,P17612,P63104,Q99640,P31946,P06493 18 +Purine metabolism 0.2755106214802621 0.7952970039872319 0.4264407559214829 1.0 0.7421709309787347 54 P55263,P30520,P31939,Q01433,P49643,Q9BY32,P60891,P07741,P14618,O43924,Q07864,P15531,P49642,P31350,Q06203,Q9P2T1,P28340,P22392,P56282,P00491,Q9UKK9,P11908,P49915 23 +Phosphatidylinositol signaling system 0.3504192976361184 0.6639667234292811 0.5067116093435642 1.0 0.8414201953319735 15 P42356,Q13572,Q8NEB9,Q01968,P0DP25 5 +Wnt signaling pathway 0.3004397220378078 0.6557202702848034 0.5120041241063042 1.0 0.8424795133021915 28 P48729,P30154,P30153,P49841,P63208,Q9HB71,Q14738,Q9HCK8,P19784,Q9UHD1,P17612 11 +Inositol phosphate metabolism 0.3514875878486128 0.623102189163444 0.5332173712336683 1.0 0.857331968885242 14 Q01968,Q8NEB9,P42356,Q13572 4 +Neurotrophin signaling pathway 0.2720030789131461 0.6138411378256512 0.5393203099930775 1.0 0.857331968885242 36 Q16539,P62258,Q02750,P46109,P31751,P49841,P36507,P61981,Q04917,P27348,Q06124,P46108,P51617,P0DP25,O00221,P63104,P31946 17 +Pancreatic cancer 0.3248085755345667 0.6026073236017702 0.5467699471982965 1.0 0.857331968885242 19 Q00534,Q02750,P31751,O00716,P42771,P10398,P11233 7 +Prostate cancer 0.3207291152650294 0.5933043788751692 0.5529774687976963 1.0 0.857331968885242 20 P08238,Q02750,P31751,P42345,P49841,P36507,O00716,P10398,P24941 9 +Long term depression 0.3371895201041353 0.5455525988726471 0.5853735150896446 1.0 0.857331968885242 14 P10398,Q02750,P30154,P30153 4 +Amino sugar and nucleotide sugar metabolism 0.2928716148461046 0.5173183769200345 0.6049339277318209 1.0 0.857331968885242 25 Q13630,P06744,P34949,Q96G03,P46926,P36871,Q06210,Q9UJ70,Q8NBZ7,Q9Y223,Q96IJ6,O60701,P51570 13 +Small cell lung cancer 0.3141697968348253 0.5145359305038194 0.6068773462462971 1.0 0.857331968885242 17 Q00534,P98170,O00716,Q13309,P24941 5 +Insulin signaling pathway 0.2505740955355141 0.5130872731869769 0.6078902736326959 1.0 0.857331968885242 45 P13807,Q02750,Q9UPT5,P06737,P46109,P42345,P31751,P49841,P36507,P10398,P17612,P46108,P0DP25 13 +Vascular smooth muscle contraction 0.3089400681972329 0.5086085255542969 0.6110266518574377 1.0 0.857331968885242 19 Q02750,O75116,P36507,P10398,P17612,P0DP25 6 +Pentose and glucuronate interconversions 0.4520687614435876 0.4695199013229822 0.6386980630660422 1.0 0.8711317986756341 5 O60701,P08236 2 +Prion diseases 0.3678878171541156 0.4675402232641629 0.6401134211262947 1.0 0.8711317986756341 8 P36507,Q02750,P31948 3 +Regulation of actin cytoskeleton 0.2363715730310679 0.4517592777322554 0.6514424091168196 1.0 0.8790198388787452 60 O15144,P26038,P36507,P15311,P35080,P46108,Q16512,Q02750,Q9Y281,P07737,Q9UQB8,O15145,P46109,P78356,O75116,Q13177,P18206,P35241,Q8N8S7,P46940,P41240,P10398,O60879 23 +Drug metabolism other enzymes 0.345051899333388 0.4459649951763276 0.6556225317603901 1.0 0.8790198388787452 10 P49915,P11172,P04183,P00492,P08236,Q9BY32,Q9BZX2 7 +Gap junction 0.2969778684938076 0.4302021173662846 0.6670486219107872 1.0 0.8869302087736132 18 Q02750,Q9BVA1,P36507,Q9BUF5,P07437,P17612,P04350 7 +Fc epsilon ri signaling pathway 0.3121037376649915 0.4175581549746966 0.6762701966408358 1.0 0.8869302087736132 14 Q16539,Q02750,P36507 3 +Focal adhesion 0.2440020223195574 0.4018983288419318 0.6877588526734129 1.0 0.8869302087736132 37 Q02750,P46109,P98170,P46108,Q16512 5 +Base excision repair 0.2941870185688287 0.3976020721991705 0.690923532801544 1.0 0.8869302087736132 16 P09429,Q07864,P56282,P12004,P27695,P13051,P18858,P39748 8 +Fc gamma r mediated phagocytosis 0.2556404210286088 0.3791495486463233 0.7045768137333388 1.0 0.8918070159841561 29 O15144,Q9Y243,Q02750,O15145,P50570,P78356,P31751,P46109,P49006,Q9Y281,P23528,P62330,P29966,P46108,Q16512 15 +Apoptosis 0.2786874396974768 0.3662691176882104 0.7141642713978251 1.0 0.8976648133542108 21 P49327,Q9Y243,Q13546,P98170,P31751,O15111,Q9UHD1,P17612,P51617,P17655,O95831 11 +Acute myeloid leukemia 0.2895643272907774 0.2894992606163548 0.7721993456226655 1.0 0.9296427781812132 13 P36507,Q02750,P10398,P31751 4 +Pyrimidine metabolism 0.2223304998939253 0.2798981926278172 0.7795556138986695 1.0 0.9296427781812132 43 Q07864,P15531,P11172,P00491,P49642,P33316,P04183,P23919,P49643,P22392,Q9NRF8,P17812 12 +Homologous recombination 0.2848583624888029 0.270858588769992 0.7864997961588578 1.0 0.9296427781812132 13 P35244 1 +Viral myocarditis 0.3013177159589908 0.2650554010595262 0.7909667836458942 1.0 0.9296427781812132 10 Q7Z406,P10321,O43432,P04439,Q04637,P42574,P78344,P35580,P35579 9 +Basal transcription factors 0.2988875878220151 0.2343438907820865 0.8147180144795247 1.0 0.9481465516128867 9 P35269,Q15542,Q12962,P29083,P13984,Q9HBM6,P78347,Q6P1X5 8 +Amyotrophic lateral sclerosis als 0.2767263442847295 0.222577492707139 0.8238643552588265 1.0 0.9481465516128867 12 Q16539,P07196 2 +Pathogenic escherichia coli infection 0.2275712750655447 0.1824040103995355 0.8552656787593429 1.0 0.9493154311943172 26 O15144,O15145,Q9BVA1,P68371,O75116,Q13464,P27348,P15311,Q9BUF5,Q14247,P07437,P63104,P04350 13 +Melanogenesis 0.2562550234682633 0.1711415037088764 0.864112502016015 1.0 0.9493154311943172 13 P49841,P36507,P0DP25,Q02750 4 +Ether lipid metabolism 0.3648006187112969 0.1589743604231658 0.8736890743303927 1.0 0.9493154311943172 4 P43034 1 +Epithelial cell signaling in helicobacter pylori infection 0.2261349588576894 0.1520589317612779 0.8791404551754973 1.0 0.9493154311943172 23 Q16539 1 +Antigen processing and presentation 0.2325873325253338 0.1396837796177892 0.8889098427395303 1.0 0.9493154311943172 16 P08238,P61289,Q9UL46,P07900,Q06323 5 +Endometrial cancer 0.232954921856175 0.1170364780249488 0.9068311468213636 1.0 0.9493154311943172 14 P49841,P36507,Q02750,P10398 4 +Axon guidance 0.209578867349153 0.1163732457537768 0.9073567381028558 1.0 0.9493154311943172 26 P49841,Q9UIW2,Q9UHD1,Q16555,Q16512,Q00535 6 +Renin angiotensin system 0.3342685620188516 0.1072987609723065 0.914551967469894 1.0 0.951344288000292 4 Q9BYT8 1 +Aminoacyl trna biosynthesis 0.1724159572079957 0.0496571078953538 0.9603956372048408 1.0 0.9668942785523902 32 Q9HA77,P54577,P49589,Q9Y285,P26639,P49591,P26640,Q9NSD9,A2RTX5,O43776 10 +Autoimmune thyroid disease 0.3345996493278718 0.0438165822956949 0.9650506090179536 1.0 0.9668942785523902 3 P04439,P49327 2 +Allograft rejection 0.3345996493278718 0.0438165822956949 0.9650506090179536 1.0 0.9668942785523902 3 P04439,P49327 2 +Graft versus host disease 0.3345996493278718 0.0438165822956949 0.9650506090179536 1.0 0.9668942785523902 3 P04439,P49327 2 +Colorectal cancer 0.1895836036259421 0.0415037811236553 0.9668942785523902 1.0 0.9668942785523902 17 P49841,P10398,Q02750,P31751 4 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7f02ed9a284cdbdeeb7ea28db5b603a4e1d8c61f --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AKR1A1", "AKR1B1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "APP", "APRT", "AQR", "ARAF", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "ATRX", "AURKA", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BAIAP2", "BCAS2", "BCKDHA", "BCL10", "BCR", "BIRC6", "BLM", "BLVRA", "BPNT1", "BRCA1", "BRD8", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CBL", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT7", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBI", "DBT", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "ETNK1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "FABP5", "FAH", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FPGS", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "IMPDH1", "IMPDH2", "INPPL1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "KIDINS220", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR3", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYN", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MFSD8", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPDZ", "MPG", "MPI", "MPP5", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCAM1", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NF1", "NFKBIE", "NIT2", "NLN", "NME1", "NME2", "NME6", "NNT", "NPC1", "NR3C1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NT5C2", "NUDT12", "NUDT5", "OAT", "OCLN", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PIAS1", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNA1", "PLXNB2", "PMPCA", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP5C", "PPT1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PTDSS1", "PTGES2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11FIP1", "RAB13", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIPK1", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SIPA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC33A1", "SLC38A1", "SLIT2", "SLK", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TAF10", "TAF2", "TAF5", "TAF6", "TAF9B", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TARSL2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TOMM40", "TP53", "TPI1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", 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14.218446601941748 48.50728155339806 0.436374163749397 0.5681669850793678 8.12289402218768 1.923903139365317 1.248358570542089 0.3688600113322806 1.0 0.005612310077743 0.0008465768608115 3.510078141066238e-08 8.034135991907747e-13 +Tcf dependent signaling in response to wnt 40 60 4.385728789882816 1.1559808132055592e-05 17.473300970873787 61.62378640776699 0.1854387909065221 0.5928765054134378 8.980116427159441 3.846157738891713 1.1264976241944151 0.36413626392076 1.0 0.0043644807500144 0.011785471900189 8.830598184191495e-06 1.764801031847921e-08 +Signaling by the b cell receptor bcr 31 44 4.378921113314933 1.192682919937127e-05 14.0873786407767 45.66747572815534 0.5600618981864348 0.5194725240755018 7.669263829832862 3.2521255837555954 1.3165243686049508 0.3716278052198193 1.0 0.0089029299634258 0.0017929291584427 2.706366172303128e-07 3.678487213168366e-11 +Dna replication pre initiation 44 60 4.361776909236394 1.290103812245924e-05 16.987864077669904 61.73300970873787 0.4288945668380205 0.5957541730468855 9.845276246498855 3.587542857888571 1.230696609236802 0.3684137615844171 1.0 0.0091729684154125 0.0018817431094496 2.1262294697935726e-06 6.556964620534642e-12 +Neddylation 41 69 4.3422029190060645 1.410611558472219e-05 21.652912621359224 72.70145631067962 0.2249049893089814 0.5831751905762216 10.995736873021038 5.895588099944547 1.324302453446783 0.3688918753546149 1.0 0.0560819073241508 0.0326824623857671 0.0005781575300495 1.946689047782047e-08 +Orc1 removal from chromatin 36 47 4.339765686435102 1.4263472168929424e-05 14.364077669902912 49.74757281553398 0.6917566411101944 0.5422658696614091 8.355189705990739 2.308567607855075 1.2721915859610031 0.3803308697876651 1.0 0.0034859239981852 0.0034703369124038 3.963206153384991e-07 1.3889947807788979e-11 +C type lectin receptors clrs 36 50 4.329542287822946 1.4941957700465023e-05 15.640776699029129 51.34708737864078 0.3190386727488686 0.5456940089786598 8.889127611188893 4.137023959900662 1.350649221433646 0.371203640545422 1.0 0.0115064399742295 0.0027125023591425 8.263831209352142e-07 4.493152693908676e-11 +Regulation of pten stability and activity 32 42 4.315411708010148 1.5930571594546805e-05 12.611650485436892 41.82281553398058 0.6486618107800725 0.5229501310802542 7.056269001912706 2.1755846965350556 1.2659780846667748 0.3745012259374719 1.0 0.0031900731237819 0.0003347950757343 2.2765036214078529e-10 5.876876567256767e-15 +Interleukin 1 family signaling 31 47 4.292864020768195 1.7638303740685757e-05 14.592233009708735 49.06310679611651 0.4308069558259447 0.5378127516815151 8.12336542865419 3.453701835311694 1.3196847762251946 0.3781683305809454 1.0 0.0100117815079471 0.013122677075633 1.8171798854140884e-05 6.132770161787599e-10 +Antigen processing ubiquitination proteasome degradation 48 94 4.290988410020075 1.7787959957882293e-05 25.228155339805824 89.88592233009709 0.3040503636743611 0.5349081840989588 12.844717984151089 7.994482069951932 1.4235342488403817 0.383588489924638 1.0 0.0295630651540025 0.0102187791156541 0.0011594730934502 3.151299773673516e-05 +Downstream signaling events of b cell receptor bcr 30 41 4.285550698970021 1.8228706930578653e-05 13.109223300970871 42.81310679611651 0.5337893000107979 0.5120527765027618 7.35013455914348 2.784583610128895 1.330630298725885 0.3688632335833426 1.0 0.0044723048440716 0.0047672462644418 1.17944319489134e-07 1.1076855390916645e-12 +Regulation of runx2 expression and activity 32 41 4.262343579777057 2.0229409441574475e-05 13.184466019417476 42.609223300970875 0.5014097272359687 0.5334388394290158 7.623733474716015 1.80350585730159 1.3084091861848088 0.3700608446837968 1.0 0.0029102285656399 0.0002876902013005 1.9910846220409516e-08 3.1098536427605954e-14 +Fceri mediated nf kb activation 29 42 4.245769077264982 2.1784490253695665e-05 13.599514563106796 43.58252427184466 0.43538002101356 0.532490131621357 7.591659945968655 2.4879291964009105 1.318650463428372 0.3690692407606546 1.0 0.0039603320298963 0.0040840095186766 7.156751783587934e-08 4.093855228197428e-13 +Cyclin a cdk2 associated events at s phase entry 30 43 4.244587221596392 2.1899617411724748e-05 13.196601941747574 42.85679611650485 0.6136168472607347 0.5150313285959647 7.221373891468615 2.098630488986879 1.3159566032429193 0.3694066609952225 1.0 0.0060275441501108 0.0069551143734033 2.963083910949487e-06 6.871900298115144e-10 +Clec7a dectin 1 signaling 33 45 4.221263054533254 2.429372318468737e-05 14.883495145631068 47.679611650485434 0.3802624296591366 0.5314258409805565 8.39359553685929 3.2641435107686965 1.369019650621671 0.3735312556615013 1.0 0.0073818564025025 0.00132313066272 1.187215610808348e-07 7.940512211361622e-12 +Scf skp2 mediated degradation of p27 p21 29 39 4.207547710519834 2.581569103821124e-05 12.78883495145631 40.70873786407767 0.5921499036968256 0.5162943652980111 7.12520288261254 1.2647657441579598 1.3047123749289669 0.3686628673319737 1.0 0.0020524288782531 0.0017566671607845 5.3683061850094324e-08 2.599301573087976e-13 +Degradation of beta catenin by the destruction complex 32 47 4.207483201326934 2.582305927556483e-05 14.8252427184466 48.63834951456311 0.4830095996380346 0.5534777326316677 8.029589918636947 2.025992551710678 1.2813542829769398 0.3757731368449524 1.0 0.005612310077743 0.0063560749071577 2.974820007852329e-07 6.891729235385061e-12 +Degradation of gli1 by the proteasome 29 39 4.20434726121733 2.6183668027979223e-05 12.514563106796116 40.61407766990291 0.5405675752115602 0.5324758124461996 7.125251251124314 1.5545410691631658 1.272200728765061 0.3678115987415289 1.0 0.0019447965050573 0.0016384890204764 4.36764178756068e-08 1.3168888139696751e-14 +Interleukin 1 signaling 30 44 4.19125506360425 2.7741557157678894e-05 13.79368932038835 46.30582524271845 0.5021606336105483 0.5332552544880472 7.891168652335007 2.7901813019255988 1.3195993763744758 0.3779352216468381 1.0 0.0066841539079899 0.0079219249747297 4.305195554458758e-06 2.7414639736095928e-11 +Transcriptional regulation by runx2 35 52 4.18414887249841 2.862364928568617e-05 16.021844660194176 51.64320388349515 0.5147340657969439 0.5490234274922848 8.286848189022676 3.0091087328640205 1.321202711135219 0.3758826947187164 1.0 0.0115064399742295 0.0027125023591425 5.182156179553925e-06 1.741591402208709e-09 +Auf1 hnrnp d0 binds and destabilizes mrna 28 39 4.179770380975356 2.9180358741554e-05 12.29126213592233 41.32281553398058 0.5322843325278358 0.5313716896545542 6.997407381130411 1.1321274049849332 1.2756329236795467 0.3681225669284069 1.0 0.0014597322722839 9.137815410524424e-05 1.0541356407082855e-09 1.1606007335763412e-15 +The role of gtse1 in g2 m progression after g2 checkpoint 35 48 4.15027249538129 3.320796937011927e-05 14.79611650485437 48.84466019417476 0.6226477470486884 0.5168095546238419 7.820323564061835 1.8499922936255029 1.3076695437390702 0.3722860732713196 1.0 0.0037980660192356 0.0038718963398175 6.022259428981136e-08 2.898526849447287e-13 +Signaling by hedgehog 37 60 4.145448386883836 3.39149390287119e-05 16.28640776699029 57.470873786407765 0.6189752673658386 0.5630638540633491 8.199307909979849 3.6419383260123857 1.1996921179618314 0.3729858641615031 1.0 0.0195546565017083 0.0298058590245865 0.0001833844583546 1.7382195227156176e-08 +Regulation of runx3 expression and activity 27 35 4.144207896763488 3.409902937323572e-05 11.46359223300971 36.730582524271846 0.6696914114866416 0.4949350431730664 6.642474003130895 1.4202887203012589 1.288769965462232 0.3632605735082652 1.0 0.0018407641855875 0.0015259573241502 3.536358333854212e-08 8.321749834727651e-15 +Fc epsilon receptor fceri signaling 32 50 4.139487346031974 3.480827990154367e-05 16.155339805825243 52.529126213592235 0.3577248991718689 0.5588293080975716 8.909749521452186 4.003836293074435 1.3201566724870089 0.369825714615891 1.0 0.0141530490628759 0.0037817225913999 2.013680729582773e-06 2.5192497572234827e-10 +Tcr signaling 32 46 4.131706616032868 3.600798228853286e-05 14.79368932038835 47.728155339805824 0.3776708616120087 0.5474588628929388 8.50292119881085 3.2417009042427978 1.3249802424411328 0.3685330173213761 1.0 0.0073818564025025 0.0089732445190698 8.964213844581752e-07 7.940512211361622e-12 +Class i mhc mediated antigen processing presentation 53 119 4.123909957665913 3.724945599925533e-05 28.725728155339805 112.89320388349516 0.3223458068895866 0.6041405327539132 13.331837148395683 9.797624658989111 1.204887601525433 0.3771461993229535 1.0 0.0494096939200414 0.0233241225024621 0.0022827017648021 4.184906840311913e-05 +Hedgehog on state 29 41 4.121042326949175 3.7716211733762606e-05 12.5752427184466 41.80339805825243 0.5567751925024539 0.5304257926517765 6.636298293339077 1.8972867972618663 1.2545866277969462 0.3643204702561447 1.0 0.0042974194252635 0.0045315560193572 8.60595648128512e-07 7.356984374510956e-12 +Negative regulation of notch4 signaling 29 38 4.116131414452152 3.852846817875566e-05 12.218446601941748 39.786407766990294 0.5856668642754154 0.5088435203982538 7.300807876201572 1.1247479582770583 1.3003786017754655 0.3684988575140048 1.0 0.001549818040453 0.0012207780133745 1.8194218069499183e-08 2.8718819103193515e-14 +Degradation of dvl 26 35 4.108788277710402 3.9774050046403886e-05 11.50728155339806 37.79611650485437 0.5954952616194853 0.5106657090472662 6.536116642578212 1.2295647923796569 1.2774118860610646 0.3695881914917919 1.0 0.0016433207319124 0.0013172485850202 2.2829721545741373e-08 4.573353564783897e-14 +Pcp ce pathway 21 48 4.108627452362053 3.9801753103363424e-05 13.383495145631068 48.61407766990291 0.2861400551198787 0.573085795011315 7.677259284018882 2.3137612538026593 1.2152839684208736 0.370148963517148 1.0 0.0058176934433743 0.0066511191128316 3.440750631687376e-07 7.251177988615327e-11 +Tnfr2 non canonical nf kb pathway 30 39 4.1070987746629815 4.0065992152893415e-05 12.75242718446602 41.54126213592233 0.4835600067503021 0.5236768662797463 7.499311873418453 1.6207832096977548 1.329411623900184 0.3708129323396963 1.0 0.0025198212347625 0.0022887430854204 1.1717577943032413e-07 1.245222378322352e-12 +Dectin 1 mediated noncanonical nf kb signaling 30 39 4.1070987746629815 4.0065992152893415e-05 12.844660194174756 41.46116504854369 0.4840649810639716 0.5219757714388732 7.477483717709433 1.5951828582954857 1.3371619060105078 0.3706757674751831 1.0 0.0019447965050573 0.0016384890204764 4.36764178756068e-08 1.7128532919174245e-13 +G1 s dna damage checkpoints 28 38 4.100125076529392 4.129269047292716e-05 12.276699029126211 40.3252427184466 0.5620621733571898 0.5261130346169095 7.080750657966309 1.8659034848764728 1.2552712987328345 0.3710523646543767 1.0 0.0029102285656399 0.0027541417385927 2.017312315690788e-07 3.5021696595493193e-13 +Cross presentation of soluble exogenous antigens endosomes 26 34 4.097192806340911 4.181905776223793e-05 11.097087378640778 36.91019417475728 0.6471378136535638 0.507052502601231 6.457500437861876 1.2421375880066114 1.2717860238430438 0.3672755762882163 1.0 0.0009206745696038 0.0006187487433082 2.343422534938485e-09 3.9350294030000415e-16 +Degradation of axin 26 34 4.097192806340911 4.181905776223793e-05 11.135922330097088 36.5 0.6371703324335989 0.5044883973483546 6.515923056292238 1.1005294401076644 1.2875505119575097 0.3689236351245595 1.0 0.0014597322722839 0.0011293669878184 1.4416500865542312e-08 1.778891956548188e-14 +Regulation of ras by gaps 26 36 4.087189934018261 4.366296487323673e-05 11.558252427184469 38.29611650485437 0.5949031665539309 0.5179046122727133 6.637200606991292 1.5039380235434 1.2829290056167597 0.3733028763215757 1.0 0.0023973594907477 0.0021465314893355 9.701514261489001e-08 8.538438900537075e-13 +Cellular response to hypoxia 27 37 4.087174557283493 4.3665857862196233e-05 12.067961165048544 40.00485436893204 0.522970313217548 0.5163863933875538 6.981963081004602 1.736242938617286 1.3015320227429066 0.3618367398400983 1.0 0.0026460936226537 0.0024373211620913 1.409670576559099e-07 1.7999439876469348e-12 +Cdt1 association with the cdc6 orc origin complex 30 37 4.08237965399704 4.457689691861333e-05 11.8373786407767 39.713592233009706 0.7088745358379469 0.5132999135100862 6.7665841522618235 1.8864642297262784 1.2345641700762902 0.3668156388656303 1.0 0.0020524288782531 0.0017566671607845 5.3683061850094324e-08 2.599301573087976e-13 +Regulation of hmox1 expression and activity 30 43 4.07439743358772 4.61336394106393e-05 12.524271844660197 45.58009708737864 0.7171016159839839 0.514573723238038 7.335701580194855 2.006274620945924 1.1938232298543638 0.3651188593292154 1.0 0.0025198212347625 0.0022887430854204 1.1717577943032413e-07 1.245222378322352e-12 +Asymmetric localization of pcp proteins 26 35 4.07434324018919 4.614438264516352e-05 11.28883495145631 37.80825242718446 0.5764639774033125 0.5188050170985335 6.482730726459962 1.1863421199640956 1.2423982841678427 0.3682278814782295 1.0 0.0020524288782531 0.0017566671607845 5.3683061850094324e-08 2.599301573087976e-13 +Metabolism of polyamines 28 38 4.067633880626914 4.7492922889746936e-05 11.783980582524272 38.49271844660194 0.5956280690899458 0.5058612771265996 6.813709458301494 1.1915745430318114 1.300721756016792 0.3709861514268986 1.0 0.0014597322722839 0.0011293669878184 1.0541356407082855e-09 1.1606007335763412e-15 +Adaptive immune system 82 193 4.059439921250898 4.919056190444415e-05 46.463592233009706 186.4004854368932 0.1339433536175087 0.6962113214501324 20.006579857169463 16.487632898609263 1.0633527271457623 0.3569087738025599 1.0 0.2118575410092393 0.1112027069625841 0.021278361020619 0.0007970697490445 +Stabilization of p53 21 37 4.056473260626796 4.981926302738415e-05 11.759708737864075 38.849514563106794 0.5626554032387434 0.5211156380328503 6.862945949053685 1.536505541452464 1.2546862993954295 0.3691198814060923 1.0 0.001740287381965 0.0014189260290535 2.8488750220203672e-08 5.192359572985538e-15 +Runx1 regulates transcription of genes involved in differentiation of hscs 21 36 4.03300255660358 5.506868032778556e-05 11.74514563106796 40.9247572815534 0.4838158037368226 0.5501011058260618 6.5789160679611225 1.5190277579548277 1.1933646193238052 0.3604187581137549 1.0 0.0039603320298963 0.0040840095186766 6.364672803557086e-07 3.924277399380811e-12 +Cell cycle checkpoints 67 140 4.028846978173516 5.605108623307764e-05 35.737864077669904 139.23300970873785 0.0395895335097635 0.683101356311267 14.89377348564558 13.286392691301824 0.9326100500655764 0.3317969957493373 1.0 0.0322633458108178 0.0032547972614776 1.13688608333815e-06 8.214769559654005e-09 +Signaling by wnt 46 86 4.012751321238844 6.001512825504207e-05 23.74757281553398 85.60194174757281 -0.0326762892388985 0.6250505086159451 11.754956357347504 6.374006384893641 0.9981199007700812 0.3457491940719926 1.0 0.0175890594143828 0.05418743176696 6.222813861993934e-05 4.4921752126357645e-06 +Signaling by notch4 29 41 3.899756224771086 9.628958865581794e-05 12.74271844660194 42.689320388349515 0.5846962923720355 0.527528574888472 7.095179574371064 1.5202779907622044 1.22282479858509 0.3678962187540617 1.0 0.0044723048440716 0.0047672462644418 9.967483917140871e-07 8.405966734255289e-11 +Hedgehog ligand biogenesis 28 39 3.897344882833192 9.72530745506628e-05 11.735436893203884 40.279126213592235 0.705289766689403 0.5138056150617029 6.1754608769009325 1.552402214168598 1.168348102852658 0.3656259469969254 1.0 0.0019447965050573 0.0016384890204764 4.36764178756068e-08 1.7128532919174245e-13 +Regulation of mrna stability by proteins that bind au rich elements 28 62 3.879175577961034 0.0001048110845931 17.303398058252426 62.189320388349515 0.3637537395774206 0.6066390862029128 8.19973289328142 2.9201480419101515 1.0954480785949263 0.3602041660944462 1.0 3.2420778459519066e-05 1.0058703128698392e-05 5.446140674922775e-10 1.795305633717364e-15 +Eukaryotic translation initiation 56 101 3.876591456433809 0.000105930003728 45.19417475728155 100.27669902912622 -0.7708270245582552 0.3856475380014496 15.071066765335097 1.8144888222625024 2.0151499677382354 0.3857325415106563 1.0 1.0 1.0 0.0635238976701175 0.0001480238274956 +Uch proteinases 21 44 3.8591809969912902 0.0001137676569296 12.934466019417476 45.69174757281554 0.4676332859413379 0.5268776688735902 7.345038379241775 2.489712786954197 1.2496925486564852 0.3629400025319104 1.0 0.0060275441501108 0.0069551143734033 2.963083910949487e-06 9.436868069535136e-11 +Switching of origins to a post replicative state 37 57 3.834437762368984 0.000125851832228 16.810679611650485 58.20873786407767 0.6859740885709421 0.5709255515574044 8.560355820358037 3.2791073494099976 1.198149892515979 0.3860301174542495 1.0 0.0073818564025025 0.0089732445190698 6.151149920657415e-06 2.7694389412322284e-09 +Synthesis of dna 56 84 3.803521898990132 0.0001426533764343 23.16990291262136 82.84708737864078 0.4375997809997383 0.6204468538632794 11.716110681669798 5.49919819946737 1.2425112242470815 0.3782848222763735 1.0 0.0175120072913789 0.0053131066018268 4.984695109826969e-06 3.744658938257495e-08 +Transcriptional regulation by runx3 21 40 3.8002176227556537 0.0001445690717885 12.155339805825244 41.550970873786405 0.5220991170779611 0.5409180415581131 7.051829317928235 1.9320556056256075 1.205315041796802 0.3587760476843317 1.0 0.0076236623955354 0.0093429514575269 6.903778523613874e-06 5.295311238111964e-10 +Dna replication 60 90 3.798028743696426 0.0001458514132774 24.50242718446602 88.36650485436893 0.2923135263536031 0.6312906600612657 12.317305449092803 5.805851117746023 1.1877285197942282 0.3655243748981305 1.0 0.0264449596361177 0.0101994394473641 2.796556339423165e-05 8.288968367776488e-09 +Pten regulation 26 67 3.777047391140143 0.0001586985435289 17.303398058252426 64.46601941747574 0.1876911775469084 0.6424585632708278 8.791141177940533 4.617012723077537 0.9726834868094096 0.3433123254029529 1.0 0.0221733636713443 0.0077260891597347 7.615368544136186e-08 1.916452561348218e-09 +Defective cftr causes cystic fibrosis 28 40 3.768829019552872 0.0001640151855633 11.91019417475728 41.73300970873787 0.7347522269055131 0.5083451081080875 6.270921717387096 1.5205957155019303 1.1156147917216153 0.3576346657028889 1.0 0.0020524288782531 0.0017566671607845 5.3683061850094324e-08 2.599301573087976e-13 +Abc transporter disorders 28 40 3.768829019552872 0.0001640151855633 11.927184466019416 42.31310679611651 0.7277639006737601 0.5118740464528959 6.253118743036628 1.9845331695932795 1.1074811893524887 0.3608608076542074 1.0 0.0029102285656399 0.0027541417385927 2.017312315690788e-07 3.6673088194963766e-12 +Antigen processing cross presentation 21 49 3.749792921833245 0.0001769806568494 13.364077669902912 51.03883495145631 0.6606344305939695 0.5456453275819227 6.483621701094183 2.525298521609755 1.0422529083240153 0.3659829171921698 1.0 0.005612310077743 0.0063560749071577 2.286828829343887e-06 5.545863505748224e-11 +G2 m checkpoints 53 84 3.726461778194311 0.0001941865029626 20.961165048543688 83.21601941747574 0.2497590522742128 0.6198120617040068 11.249096904504546 6.6438113169442845 1.0983784482763044 0.3587806160447286 1.0 0.0035480208810806 4.208266639220992e-05 2.3555378212530764e-08 2.0372947602108391e-10 +Beta catenin independent wnt signaling 21 53 3.720372239116368 0.000198929357065 14.62864077669903 53.63106796116505 0.2467758551278147 0.5921017130101743 7.928102596073744 3.656329241145158 1.1545689159912884 0.3649233327912332 1.0 0.0175120072913789 0.0260774389953396 4.984695109826969e-06 3.744658938257495e-08 +Apc c mediated degradation of cell cycle proteins 33 58 3.643143793146614 0.0002693282794461 16.58009708737864 56.25970873786408 0.4894986081915347 0.5846445085026403 8.225929403640711 3.549651687085986 1.2134956516570392 0.3755323963670207 1.0 0.0064607496534721 0.0075904072731156 3.808446935944453e-06 1.110842822553605e-09 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 29 50 3.624663039693503 0.0002893384450373 14.026699029126211 48.65533980582524 0.5636343266746052 0.5641920682636952 7.183906351200202 2.917580729254371 1.1799230201059223 0.3753446211108022 1.0 0.0039603320298963 0.0040840095186766 6.364672803557086e-07 3.5109251006493493e-11 +Nervous system development 98 221 3.6180713548254175 0.0002968065752069 72.11893203883496 210.9927184466019 -0.4831722305170725 0.5473670515892652 29.786749038405222 11.960998326208504 1.4364728531430393 0.3670615320407082 1.0 0.1543119052833902 0.2529523979399194 0.0117343093697896 2.3546625980871828e-05 +Eukaryotic translation elongation 40 77 3.608324937777368 0.0003081803580176 40.33980582524272 76.70873786407768 -1.170264854227122 0.3173586097479524 13.865899638243102 1.3501604935966776 2.213815111182405 0.3781772268307828 1.0 1.0 1.0 0.3685282014965862 0.0037949128027229 +Intracellular signaling by second messengers 45 93 3.5424972902156937 0.0003963574950525 23.20145631067961 86.0631067961165 0.1421070399989671 0.655790329270176 10.291654542344736 8.129468035609259 0.948765500839012 0.3384114915870303 1.0 0.0964040929059835 0.0246145445697769 1.4745550355899871e-05 9.472903105839051e-07 +Abc family proteins mediated transport 31 52 3.531341515427877 0.0004134575462919 13.317961165048544 51.41990291262136 0.8313343047168666 0.503384351224866 6.603791770344115 3.017890343683211 1.0258838915302482 0.3681223740303289 1.0 0.0052148394647031 0.005792379744814 1.7499193852019478e-06 2.497125890722753e-10 +Signaling by interleukins 57 110 3.5169793626286343 0.0004364877173268 26.51456310679612 106.8131067961165 0.2659215907627361 0.6379218100870152 12.507367985924851 6.646155400677433 1.0797762015608217 0.3618033258723105 1.0 0.0010161722880494 0.0006160597345226 2.5316868517509397e-06 3.731054622993663e-08 +Transcriptional regulation by runx1 27 66 3.5142625345622243 0.0004409767495616 17.660194174757283 67.73058252427184 0.0956433719082077 0.6467498474297692 8.588831535590984 5.0191610185934845 0.9164516867594036 0.3343217460909707 1.0 0.0051759819789282 0.0142770645433407 1.5375164024096766e-05 4.7774557613153363e-08 +Response of eif2ak4 gcn2 to amino acid deficiency 38 76 3.432779585833553 0.000597427562458 39.550970873786405 76.03155339805825 -1.127048342201767 0.3185079045659907 13.761485019110056 1.5173669435319213 2.220942857496925 0.3803423215749384 1.0 1.0 1.0 0.4016041233206363 0.0157288053210816 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 32 51 3.407610023358496 0.0006553448233175 21.27912621359223 50.43446601941748 -0.6423341772855271 0.4501870221883518 8.810973476604579 1.4474874301684992 1.4039245476891489 0.3707470696386276 1.0 1.0 1.0 0.0549638769430376 0.0004954067345962 +Signaling by notch 24 58 3.370902881439611 0.0007492226547596 14.941747572815531 58.85679611650485 0.4411392402814988 0.620198315051001 7.402538586762891 3.488034668926816 0.978025139431841 0.3518651286473304 1.0 0.0055528270016818 0.0154457523693027 8.296075173845918e-05 2.884989409212634e-07 +Nonsense mediated decay nmd 42 86 3.295692606778218 0.0009817937711613 42.101941747572816 85.76941747572816 -1.1457400111181046 0.3421409039593034 15.03730946151162 2.536670214507658 2.1258465434199816 0.3829653082446096 1.0 1.0 1.0 0.2792072601058594 0.0070689045564294 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 19 32 3.290834377240449 0.0009989070632003 10.99514563106796 30.575242718446603 0.1584518755541417 0.6126046167689052 6.479989791445523 1.8065868396091345 1.0359782039154073 0.3387863879536805 1.0 1.0 0.3655284832956332 0.3174825468726979 0.0071658996193174 +Mapk family signaling cascades 47 96 3.234891651572647 0.001216888990899 23.104368932038835 88.2864077669903 0.366998662581797 0.5880023171217027 11.41393630950696 5.588694353030067 1.1675181672079205 0.3704838978698669 1.0 0.0775528091516589 0.053305438590565 0.0002051271783766 4.023492093912137e-07 +S phase 52 99 3.2313879269711108 0.0012319062310981 25.58252427184466 94.497572815534 0.3936025929765626 0.6471527110395977 12.311904628033766 6.6662819095148595 1.1799446716032989 0.3778079902664983 1.0 0.0380087357307307 0.0179719199144886 0.0001231227125952 2.196878481972525e-06 +Separation of sister chromatids 46 103 3.231107587570386 0.0012331151526205 27.25728155339806 104.59466019417476 0.1913519656937572 0.6759734454858931 10.904342253831215 7.99139528936842 0.9289444053822858 0.343574417926859 1.0 0.0517625943859567 0.0935981394072189 7.184080596972841e-06 2.1874308568672543e-09 +Selenoamino acid metabolism 35 89 3.018578113721195 0.0025396392103966 45.359223300970875 88.94660194174757 -1.2269036973447986 0.3270935993226454 16.116146621354947 1.9650003351851577 2.2110932203759184 0.3833177831487697 1.0 1.0 1.0 0.4848564647917259 0.0056781561880928 +Ub specific processing proteases 38 80 2.9984893027572075 0.0027132168095689 17.070388349514563 72.1116504854369 0.5586830572298067 0.5701992170768696 9.734454714417684 6.256038651254875 1.0924507106168106 0.3735968680377643 1.0 0.0339072929728963 0.0574136821119774 1.790050608277115e-05 6.271719972380004e-08 +Apoptosis 40 89 2.9337466465720605 0.0033489745043764 22.723300970873787 88.14805825242719 0.0393529046833614 0.6051308661069602 11.01526481781096 5.029516867347871 1.0330743537895812 0.3410297528233371 1.0 0.0065027336576065 0.0184179736538357 0.0001312327472383 4.4260224143399355e-08 +Diseases of signal transduction by growth factor receptors and second messengers 65 156 2.9252670174780446 0.0034416077602958 38.23543689320388 143.25485436893203 0.0760803095091799 0.6705657643193705 15.041864122024071 11.50835917079556 0.9951358349988204 0.3506422537450402 1.0 0.2061532146946217 0.3985398668948996 0.0160471623493422 7.651538572520073e-05 +Cilium assembly 50 67 2.846908359538776 0.0044146068608761 17.691747572815533 60.07281553398058 0.7163847705434252 0.5030560453085753 8.208427462797529 7.176657065505861 1.1196611241046792 0.3669144822823486 1.0 0.5816210605726648 0.528007824876168 0.8268643709953708 0.6722824462804593 +Recruitment of mitotic centrosome proteins and complexes 20 33 2.842505769704448 0.0044760420927099 10.75485436893204 32.21116504854369 0.6690475765725821 0.4763419930316802 4.776113780352103 4.3238525164960775 1.0085704741220791 0.3559421309914655 1.0 0.3219228357858488 0.1862598674919939 0.5969051653450472 0.7687270582276297 +Interconversion of nucleotide di and triphosphates 9 17 2.831731770134463 0.0046296667516017 5.497572815533981 17.694174757281555 -0.1681971791529782 0.4897251001051131 3.6513721229998217 1.854845412275771 1.091743890900105 0.3245015655397826 0.002550019615475 0.1155957163384056 0.2223047329091382 0.0244664942800011 0.0012863968531589 +Programmed cell death 26 101 2.8193138350300924 0.0048126438591382 24.810679611650485 99.90533980582524 0.0752454735319569 0.6272894434318409 12.51748611988162 5.728761589606555 1.018486798771118 0.3435170341557741 1.0 0.0097972095160049 0.028919800101654 0.0004220754015876 1.37036207321201e-07 +Mitotic metaphase and anaphase 39 137 2.813956753613744 0.0048935811235668 32.713592233009706 137.5606796116505 0.2278139082304805 0.7664396684305591 11.189259313693016 9.232104574685764 0.7198774942531959 0.3163562507137944 1.0 0.0890130336190231 0.1707049877158561 9.125772536873877e-06 3.012656782142616e-09 +Anchoring of the basal body to the plasma membrane 21 35 2.781454320370655 0.0054115945812078 10.25 32.03398058252427 0.6177589631738116 0.4929072994149106 4.597184131808032 4.443147956867209 0.9752582334781768 0.3486333170600847 1.0 0.3626106066392318 0.2319888267069046 0.408165406574172 0.4941875485478696 +Deubiquitination 44 100 2.690643925375768 0.0071314266277555 21.274271844660195 90.48543689320388 0.4172727973060445 0.5987827475213043 11.64961844468234 9.030277095459189 1.0784969503501256 0.3703499256790007 1.0 0.085412898243946 0.1632643902509063 0.0010018666474111 3.018322406608974e-06 +Aurka activation by tpx2 21 34 2.6770448339878543 0.0074274695280505 10.276699029126211 31.893203883495147 0.5790832053921023 0.5039527741558584 4.914920890107843 4.281168113347361 0.9784215516709706 0.3534896123548716 1.0 0.2922756805728106 0.1554832015057707 0.5335587935482642 0.6965044033593579 +Regulation of plk1 activity at g2 m transition 22 39 2.6530306853164585 0.00797726184582 10.817961165048544 36.351941747572816 0.4236275579912321 0.5790160572388595 5.051517864598315 4.566118480415196 0.8709022927963019 0.3353187527061693 1.0 0.3378643758427397 0.2037147080402499 0.3552020223242721 0.6171408215140904 +Recruitment of numa to mitotic centrosomes 22 37 2.6295333555220517 0.0085502143589744 11.883495145631068 35.75485436893204 0.624756920034884 0.5097170288431273 5.3811987888681685 4.283134766195611 1.0244661495687433 0.3603491445972374 1.0 0.3472525306689195 0.2142764757579067 0.6476315526587827 0.6438358819320652 +Cytoprotection by hmox1 21 65 2.5982731115142403 0.009369394044741 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 1.0 0.0148643595785498 0.0213556169291773 1.3995055076447344e-05 1.1475329620692877e-08 +Hiv infection 52 137 2.5612258664454406 0.010430352053997 31.436893203883496 133.40533980582524 -0.1338437194651512 0.723375127084396 13.716915998961836 8.323453273677645 0.6776538527045113 0.2970465700834592 1.0 0.0784094341468755 0.0166145223857314 0.0002159528631997 1.3178928555145404e-07 +Metabolism of nucleotides 18 45 2.497839219844157 0.0124952851668305 13.689320388349516 45.83252427184466 -1.1184294987896846 0.354071171489312 8.929637710188212 3.5415166567437466 1.2782778290942398 0.3409376828853995 0.0080423695565861 0.3219228357858488 0.0442161560616649 0.0146538273261742 0.0019737688005078 +Cellular response to chemical stress 23 75 2.43252818839226 0.0149938243727472 16.92233009708738 74.85436893203884 0.6393995551476427 0.564482392286313 7.443234134196828 3.8890130701767585 0.935566980068825 0.3664371412566685 1.0 0.0244955629919658 0.0390712286884639 9.314711482102516e-05 2.0771286811827303e-08 +Negative regulation of mapk pathway 8 14 2.4073556459274927 0.0160685132757922 4.233009708737864 11.558252427184469 0.0212130805321306 0.5707340991163712 2.6892590508584675 1.8963441717773477 0.8993836023547437 0.3134524971647613 1.0 1.0 1.0 0.2179356607727124 0.0957448321565225 +Cellular response to starvation 36 89 2.384006959658328 0.0171252784954241 41.6747572815534 88.34466019417475 -1.0303047421198284 0.3510932752390905 14.200404878998892 2.6553930524825846 2.028552953689577 0.3779284314527495 1.0 1.0 1.0 0.6617026179688178 0.1394136617814829 +Cyclin d associated events in g1 8 13 2.319383944042592 0.0203742274481981 4.366504854368932 10.116504854368932 0.1222182547646903 0.5717022199186504 2.5273541207987025 1.6637247419470345 0.9055693104495058 0.3101665598109623 1.0 1.0 1.0 0.6706077438596076 0.0660317196551079 +Copi independent golgi to er retrograde traffic 14 27 2.305180789607083 0.0211564502965824 8.053398058252426 27.12135922330097 0.302798844042666 0.6258770271233919 3.9403394347399954 2.2597856451930913 0.8982376608905671 0.3350370934950194 1.0 1.0 1.0 0.2994428025832826 0.0660317196551079 +Cooperation of prefoldin and tric cct in actin and tubulin folding 8 18 2.2943412471475564 0.0217709050770946 7.783980582524272 16.844660194174757 0.1576028180557599 0.5228289011450986 4.193665551388727 1.2695636552860448 1.1333901377691142 0.3494472368572205 1.0 1.0 1.0 0.029757296929711 0.0103633783340074 +Erks are inactivated 4 6 2.272717700424428 0.0230431972965106 2.7572815533980584 6.298543689320389 -0.1651013262749268 0.5284457637223188 1.7332612474164548 0.8650146278206343 0.8986606977851365 0.299653650838943 1.0 1.0 1.0 0.0280420066437826 0.0140894483762481 +Developmental biology 108 266 2.253628514432497 0.0242195479372722 83.72815533980582 256.43203883495147 -0.5814417711887411 0.5435048152949694 32.55971188976957 18.326402586582073 1.2607699755195518 0.3604361411334405 1.0 0.2014674441212967 0.4586904627514304 0.1314751001731891 0.0094173927594897 +Platelet sensitization by ldl 4 6 2.2364487191658124 0.0253223928609456 2.1990291262135924 5.449029126213592 0.1837475285624822 0.5280601302474661 1.4760873987878906 1.0770437917042883 0.908152314259454 0.297897263394418 1.0 0.0683810764565047 0.1349531130589082 0.050241067872642 0.16360549489043 +Metabolism of folate and pterines 1 9 2.234528738530848 0.0254483037858765 1.8106796116504855 8.368932038834952 1.1027495377425318 0.3107646321591615 1.2630224668311476 0.7725922983430199 0.836443902773376 0.2729501818402672 1.0 0.0683810764565047 0.1349531130589082 0.050241067872642 0.16360549489043 +G1 s specific transcription 0 11 2.1825797251020917 0.0290667742202845 2.5509708737864076 10.196601941747574 0.5500386685258407 0.4863464308926273 1.8824235641533549 1.373355364810755 0.8859821752763714 0.3128546874322141 1.0 0.1280604643503683 0.2445730022705269 0.510851629797044 0.7650208428589309 +Transcriptional activation of mitochondrial biogenesis 1 12 2.1644380751750227 0.0304307443258344 3.75 12.432038834951456 -0.1281260555520316 0.4644247929939951 2.038018502731447 1.8754268688059847 1.067682850482272 0.2998511345858375 1.0 0.2143583684675494 0.3896854720293997 0.3532043826100663 0.4546614400199755 +Cholesterol biosynthesis 3 17 2.0471134463347127 0.0406469470411248 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 1.0 0.1071891284628969 0.0015052123544451 0.0024740226177806 0.0052582215982291 +Activation of atr in response to replication stress 14 22 2.030553134135385 0.0423003459731714 5.179611650485437 19.679611650485437 0.1285647335300941 0.6575195684392049 3.862537503467055 3.0152157572513594 0.7447824953405174 0.2942694440452609 1.0 1.0 0.0513963234576887 0.064307133891248 0.2812242430558347 +Netrin 1 signaling 4 11 2.016916072250313 0.0437042725183589 3.766990291262136 9.655339805825244 -0.1325110296822746 0.558199221376826 2.44136633515538 2.155968376812043 0.872460835405313 0.2955598798754135 1.0 0.1444128696349771 0.2732850813359189 0.5568666172945154 0.2151867556135544 +Retrograde transport at the trans golgi network 5 18 2.007102309955109 0.0447387703303774 4.779126213592233 17.143203883495147 0.3613851487031342 0.4884664603565215 2.6268315318443034 3.9886218545053063 1.007707670827069 0.3163228122840523 1.0 0.2068720246493716 0.0115248505447769 0.0307995556081591 0.0305407497227627 +Darpp 32 events 4 9 1.999174308345528 0.0455894973261763 3.337378640776699 8.611650485436893 -0.1363675416686346 0.6078568346690442 2.0539474006391516 1.0656417885616585 0.772534859100602 0.2862934874267145 1.0 1.0 1.0 0.3891747515056749 0.631511633602643 +Dna damage recognition in gg ner 7 17 1.97130570506906 0.0486889192023096 5.092233009708738 16.953883495145632 0.1211680075909219 0.6725327205218893 3.0251755728680196 1.8565835273947704 0.7064059605185126 0.2898124991744362 1.0 1.0 0.048990890514732 0.2269450626655096 0.0082637154660588 +Aggrephagy 9 15 1.9692059297978255 0.0489294482320432 5.053398058252427 15.303398058252426 0.0176530269767163 0.5860415978812633 3.0019513244173344 1.710245569943332 0.9388436016613388 0.3189258517008108 1.0 1.0 1.0 0.5676800659750835 0.228153712059568 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..72317ecb703ec58c63ff3dac83e0dbfa61631dd0 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 1397, + "title": "Average number of proteins per term", + "value": 20.211166785969937 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3aafe1865227f034b78696003519f271b75d11c2 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d41346fd1990f28f3881c92a4d3798bf99e3dee1 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,615 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Signaling by robo receptors 0.5532865525086216 5.807048893638418 6.35835732948393e-09 8.882585768526921e-06 8.882625190686051e-06 135 P46778,P62191,P51665,P46783,P26373,P27635,P62917,P49721,P18621,Q9UNM6,P46781,P28070,P15880,Q13200,P28074,Q15008,P62269,P35080,Q99460,Q15370,Q16512,P48556,P61247,P61513,P20618,P62841,P62333,P62847,O00232,P60900,P07737,P17612,P17980,P23396,P62861,P25788,P62241,P62195,P84098,P62899,P25789,Q99436,P62906,P25787,P39019,P39023,P83731,Q13177,Q04637,P83881,O75832,P62750,P61289,Q8N8S7,Q9UL46,P28066,P62495,P62081,P05387,P32969,P28072,P62753,P62277,P62266,P05388,O75122,P49720,P08708,Q7Z460,P25786,O43242 71 +Regulation of expression of slits and robos 0.5546546561295479 5.024523100979691 5.046850527292964e-07 0.0007047967106138 0.0003525225093321 119 P46778,P62191,P51665,P46783,P27635,P62917,P49721,P18621,Q9UNM6,P46781,P28070,P15880,Q13200,P28074,Q15008,P62269,Q99460,Q15370,P48556,P61247,P61513,P20618,P62841,P62333,P62847,O00232,P60900,P17980,P23396,P62861,P25788,P62241,P62195,P84098,P62899,P25789,Q99436,P62906,P25787,P39019,P39023,P83731,Q04637,P83881,O75832,P62750,P61289,Q9UL46,P28066,P62495,P62081,P05387,P32969,P28072,P62753,P62277,P62266,P05388,P49720,P08708,P26373,P25786,O43242 63 +Mitotic g1 phase and g1 s transition 0.6088155258704018 4.630693396812155 3.644431979088481e-06 0.0050783421496902 0.0014013848381585 79 P00374,P62191,P30153,P51665,O43242,P04183,P49721,P49736,O00716,P42771,P28070,Q9UNM6,Q13200,P15927,P28074,P24941,Q15008,P49643,Q99460,P48556,Q00534,P20618,P30154,P62333,Q7L590,P63208,O00232,P60900,Q9UBD5,P17980,P33991,P25788,Q07864,P62195,P25789,P49642,Q99436,P31751,P31350,P25787,P35244,O43913,O00231,O75832,P61289,Q9UL46,P28066,P63151,P28072,P25205,Q13309,P49720,P25786,P06493 54 +Mitotic g2 g2 m phases 0.5752939908779192 4.489589067402541 7.136070480306955e-06 0.009919599011316 0.0014013848381585 92 O75330,Q15691,P62191,O14980,P30153,P51665,O43242,Q9H6D7,P49721,Q9UNM6,O00716,P61981,P28070,P07900,Q13200,P28074,Q14203,P24941,Q15008,Q99460,Q99640,P48556,Q96CS2,P20618,Q9BVA1,P30154,P62333,P63208,O00232,P60900,P07437,P17612,P17980,O75935,P25788,P08238,P62195,P25789,Q99436,P25787,P41208,P61163,O00231,P23258,Q9BUF5,O75832,P61289,Q9UL46,P62258,P28066,P63151,P28072,O95067,P43034,Q13409,P25786,O14965,P49720,Q7Z460,O94927,P04350,P06493 62 +Hedgehog off state 0.6684615548002796 4.473797899071367 7.684237528726712e-06 0.0106775074345877 0.0014013848381585 51 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q96J02,Q99460,P48556,P48729,P62333,P20618,Q9BVA1,Q9Y496,P63208,O00232,P60900,P17612,P17980,P25788,P25789,Q99436,P25787,P49841,Q9BUF5,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,P04350,O43242 35 +Mapk6 mapk4 signaling 0.6721469532672365 4.396297929506604 1.1011277279315834e-05 0.0152651275351089 0.0014013848381585 47 P62191,P51665,P49721,P25685,Q9UNM6,P28070,Q13200,P28074,Q15008,P06493,Q99460,Q16512,P48556,P62333,P20618,O00232,P60900,P17612,P17980,P25788,P62195,P25789,Q99436,P25787,Q13177,P04792,O75832,P61289,Q9UL46,P28066,Q9HCE1,P28072,P49720,P25786,O43242 35 +Tcf dependent signaling in response to wnt 0.6233071647909705 4.385728789882816 1.1559808132055592e-05 0.0160194469651797 0.0014013848381585 60 P62191,P51665,P98170,P30153,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q9UBL3,Q99460,P48556,P48729,P62333,P20618,P30154,O00232,Q14738,P60900,P17980,P25788,P62195,P25789,Q99436,P31751,P25787,P49841,P40818,Q9HCK8,O75832,P61289,Q9UL46,P63104,P28066,P28072,P19784,P49720,P25786,O43242 40 +Signaling by the b cell receptor bcr 0.6857543612028775 4.378921113314933 1.192682919937127e-05 0.0165238383745821 0.0014013848381585 44 P62942,P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,O00221,P25788,P25789,Q99436,P25787,O43865,O75832,P61289,Q9UL46,P28066,O95999,P28072,P49720,P25786,O43242 31 +Dna replication pre initiation 0.6205441348942908 4.361776909236394 1.290103812245924e-05 0.0178614259840908 0.0014013848381585 60 P62191,P51665,P49721,P49736,Q9UNM6,O00716,P28070,P15927,P28074,Q15008,P24941,Q13200,P49643,Q99460,P48556,P62333,P20618,Q7L590,O00232,P60900,Q9UBD5,P17980,P33991,P25788,Q07864,P62195,P25789,P49642,Q99436,P25787,O43913,P35244,O00231,O75832,P61289,Q9UL46,P28066,O60684,P52294,P28072,P25205,P49720,P25786,O43242 44 +Neddylation 0.5872572462582654 4.3422029190060645 1.410611558472219e-05 0.019513480916252 0.0014013848381585 69 Q93034,P51665,P49721,Q9UNM6,P28070,P61201,Q13200,P28074,Q15008,Q99460,Q15370,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,Q7L5N1,O75832,P61289,Q9NZJ0,Q9UL46,Q9UBW8,P28066,Q96GG9,O94888,Q9UNS2,Q9NXF7,P28072,Q86VP6,Q86X83,Q13309,P49720,Q92905,P25786,O43242 41 +Orc1 removal from chromatin 0.6648726978130266 4.339765686435102 1.4263472168929424e-05 0.0197289978394894 0.0014013848381585 47 P62191,P51665,P49721,P49736,Q9UNM6,P28070,Q13200,P28074,Q15008,P24941,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,Q9UBD5,P17980,P33991,P25788,P62195,P25789,Q99436,P25787,O43913,O75832,P61289,Q9UL46,P28066,P28072,P25205,Q13309,P49720,P25786,O43242 36 +C type lectin receptors clrs 0.6538046133726438 4.329542287822946 1.4941957700465023e-05 0.0206577154615639 0.0014013848381585 50 P62191,P51665,P61081,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,Q16512,P48556,P62333,P20618,P63208,O00232,P60900,P17612,P17980,P25788,P62195,P25789,Q99436,P25787,Q13177,O43865,O75832,P61289,Q9UL46,P28066,P49427,O95999,P28072,P49720,P25786,O43242 36 +Regulation of pten stability and activity 0.689369568729946 4.3154117080101475 1.5930571594546805e-05 0.0220093661043283 0.0014013848381585 42 P51665,P98170,Q92995,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P31751,P25787,O75832,P61289,Q9UL46,P46934,P28066,P28072,P19784,P49720,P25786,O43242 32 +Interleukin 1 family signaling 0.6588707178104442 4.292864020768195 1.7638303740685757e-05 0.0243398182559996 0.0014013848381585 47 P51665,P49721,Q9UNM6,Q06124,P28070,Q13200,P28074,Q15008,Q99460,P51617,P48556,P09429,Q02750,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 31 +Antigen processing ubiquitination proteasome degradation 0.5529550189233454 4.290988410020075 1.7787959957882293e-05 0.0245437815628688 0.0014013848381585 94 Q9GZZ9,Q93034,P51665,O43242,P49721,Q9UNM6,P28070,Q5T4S7,Q13200,P28074,Q15008,Q96J02,Q99460,Q15370,Q9BSL1,P48556,P19474,P20618,P62333,Q16763,P63208,O00232,P60900,P17980,Q96PU5,P25788,P25789,Q99436,P25787,Q9C0C9,P68036,O75832,P61289,Q15386,Q7Z6Z7,Q9UL46,P46934,P28066,Q8TDB6,P49427,Q9UII4,P52888,P28072,Q9Y4B6,Q13309,P49720,P25786,Q8IYU2 48 +Downstream signaling events of b cell receptor bcr 0.6911396174243098 4.285550698970021 1.8228706930578653e-05 0.0251442188423536 0.0014013848381585 41 P62942,P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,O00221,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,O95999,P28072,P49720,P25786,O43242 30 +Regulation of runx2 expression and activity 0.6879751614220097 4.262343579777057 2.0229409441574475e-05 0.027865170671135 0.0014013848381585 41 P62191,P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,P49841,O75832,P04150,P61289,Q9UL46,P28066,P28072,Q13309,P49720,P25786,O43242 32 +Fceri mediated nf kb activation 0.6799764680261905 4.245769077264982 2.1784490253695665e-05 0.0299748348544305 0.0014013848381585 42 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P49427,O95999,P28072,P49720,P25786,O43242 29 +Cyclin a cdk2 associated events at s phase entry 0.6739661421860484 4.244587221596392 2.1899617411724748e-05 0.0301308374243086 0.0014013848381585 43 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,P24941,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P31751,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q13309,P49720,P25786,O43242 30 +Clec7a dectin 1 signaling 0.6589161221281883 4.221263054533254 2.429372318468737e-05 0.0333692848001887 0.0014013848381585 45 P62191,P51665,P61081,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O43865,O75832,P61289,Q9UL46,P28066,P49427,O95999,P28072,P49720,P25786,O43242 33 +Scf skp2 mediated degradation of p27 p21 0.6915723246065807 4.207547710519834 2.581569103821124e-05 0.0354223925011735 0.0014013848381585 39 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,P24941,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q13309,P49720,P25786,O43242 29 +Degradation of beta catenin by the destruction complex 0.6480212348743117 4.207483201326934 2.582305927556483e-05 0.0354323215161835 0.0014013848381585 47 P51665,P30153,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P48729,P62333,P20618,P30154,P63208,O00232,Q14738,P60900,P17980,P25788,P25789,Q99436,P25787,P49841,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 32 +Degradation of gli1 by the proteasome 0.6911292163878623 4.20434726121733 2.6183668027979223e-05 0.0359181324414172 0.0014013848381585 39 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q96J02,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17612,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 29 +Interleukin 1 signaling 0.6610290636594621 4.19125506360425 2.7741557157678894e-05 0.0380141072457965 0.0014013848381585 44 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P51617,P48556,P09429,Q02750,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 30 +Transcriptional regulation by runx2 0.6291868705455017 4.18414887249841 2.862364928568617e-05 0.0391988490925418 0.0014013848381585 52 P17931,P62191,P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,P06493,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P31751,P25787,P49841,O75832,P04150,P61289,Q9UL46,P28066,P28072,Q13309,P49720,P25786,O43242 35 +Auf1 hnrnp d0 binds and destabilizes mrna 0.6877316668293387 4.179770380975356 2.9180358741554e-05 0.0399458174355296 0.0014013848381585 39 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,P04792,Q04637,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 28 +The role of gtse1 in g2 m progression after g2 checkpoint 0.6377979733372948 4.15027249538129 3.320796937011927e-05 0.0453326306427585 0.0014013848381585 48 Q15691,P51665,P49721,Q9UNM6,P28070,P07900,Q13200,P28074,Q15008,P06493,Q99460,P48556,P62333,P20618,Q9BVA1,O00232,P60900,P17980,P25788,P08238,P25789,P62195,Q99436,P25787,Q9BUF5,O75832,P61289,Q9UL46,P28066,P28072,O95067,P49720,P25786,P04350,O43242 35 +Signaling by hedgehog 0.5958948733746 4.145448386883836 3.39149390287119e-05 0.0462750612532688 0.0014013848381585 60 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q96J02,Q99460,P48556,P48729,P62333,P20618,Q9BVA1,Q9Y496,P63208,O00232,P60900,P17612,P17980,P25788,P62195,P25789,Q99436,P25787,P49841,Q9BUF5,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P49720,P25786,P04350,O43242 37 +Regulation of runx3 expression and activity 0.7031958932531668 4.144207896763488 3.409902937323572e-05 0.0465203115150366 0.0014013848381585 35 P51665,P49721,Q9UNM6,P42771,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 27 +Fc epsilon receptor fceri signaling 0.6302533040224662 4.139487346031974 3.480827990154367e-05 0.0474646057519353 0.0014013848381585 50 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,Q16512,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,Q13177,O43865,O75832,P61289,Q9UL46,P28066,P49427,O95999,P28072,P49720,P25786,O43242 32 +Tcr signaling 0.6413972790166719 4.131706616032868 3.600798228853286e-05 0.0490597594374111 0.0014013848381585 46 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,Q16512,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,Q13177,O75832,P61289,Q8N8S7,Q9UL46,P28066,P49427,O95999,P28072,P49720,P25786,O43242 32 +Class i mhc mediated antigen processing presentation 0.4822072944346297 4.123909957665913 3.724945599925533e-05 0.0507076429209372 0.0014013848381585 119 Q9GZZ9,Q93034,P51665,O43242,P49721,Q9UNM6,P28070,Q5T4S7,Q13200,P28074,Q15008,Q96J02,Q99460,Q15370,Q9BSL1,P48556,P09429,P19474,P20618,P62333,Q16763,P63208,O00232,P60900,O95486,O95487,P17980,Q96PU5,P25788,P25789,Q99436,P25787,Q9C0C9,P68036,O75832,P61289,Q15386,Q7Z6Z7,Q9UL46,P46934,P28066,Q8TDB6,P49427,Q6P179,Q9UII4,P52888,P28072,Q9Y4B6,Q15436,Q13309,P49720,P25786,Q8IYU2 53 +Hedgehog on state 0.6688789304028526 4.1210423269491745 3.7716211733762606e-05 0.0513264577914189 0.0014013848381585 41 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q96J02,Q99460,P48556,P48729,P62333,P20618,Q9Y496,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 29 +Negative regulation of notch4 signaling 0.6841903988781629 4.116131414452152 3.852846817875566e-05 0.0524023692416971 0.0014013848381585 38 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,P63104,Q9UL46,P28066,P28072,P49720,P25786,O43242 29 +Degradation of dvl 0.6981217698419121 4.108788277710402 3.9774050046403886e-05 0.0540498935844005 0.0014013848381585 35 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 26 +Pcp ce pathway 0.6326138536084469 4.108627452362053 3.9801753103363424e-05 0.0540865037090301 0.0014013848381585 48 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P07737,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +Tnfr2 non canonical nf kb pathway 0.6777387662122316 4.1070987746629815 4.0065992152893415e-05 0.0544356295631401 0.0014013848381585 39 P62191,P51665,P61081,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 30 +Dectin 1 mediated noncanonical nf kb signaling 0.6777387662122317 4.1070987746629815 4.0065992152893415e-05 0.0544356295631401 0.0014013848381585 39 P62191,P51665,P61081,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 30 +G1 s dna damage checkpoints 0.6819737039166733 4.100125076529392 4.129269047292716e-05 0.0560547190634255 0.0014013848381585 38 P51665,P49721,Q9UNM6,P42771,P28070,Q13200,P28074,Q15008,P24941,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 28 +Cross presentation of soluble exogenous antigens endosomes 0.7012099375061688 4.097192806340911 4.181905776223793e-05 0.056748608847138 0.0014013848381585 34 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 26 +Degradation of axin 0.7012099375061688 4.097192806340911 4.181905776223793e-05 0.056748608847138 0.0014013848381585 34 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 26 +Regulation of ras by gaps 0.690196707567573 4.087189934018261 4.366296487323673e-05 0.0591753429904528 0.0014013848381585 36 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 26 +Cellular response to hypoxia 0.685243704648441 4.087174557283493 4.3665857862196233e-05 0.0591791454969008 0.0014013848381585 37 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,Q15370,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 27 +Cdt1 association with the cdc6 orc origin complex 0.6845741909579127 4.08237965399704 4.457689691861333e-05 0.0603758395932911 0.0014013848381585 37 P62191,P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,Q9UBD5,P17980,P25788,P62195,P25789,Q99436,P25787,O43913,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 30 +Regulation of hmox1 expression and activity 0.6515766983971437 4.07439743358772 4.6133639410639304e-05 0.0624171773960469 0.0014013848381585 43 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q13309,P19784,P49720,P25786,O43242 30 +Asymmetric localization of pcp proteins 0.6932063901170025 4.07434324018919 4.614438264516352e-05 0.0624312494627113 0.0014013848381585 35 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,P49720,P25786,O43242 26 +Metabolism of polyamines 0.6774860460618515 4.067633880626914 4.7492922889746936e-05 0.0641959651004604 0.0014116513463186 38 P51665,P19623,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q6QHF9,P49720,P25786,O43242 28 +Adaptive immune system 0.4528409866421721 4.059439921250898 4.919056190444415e-05 0.0664127969491239 0.0014203573561072 193 P30153,P49721,Q06124,P28070,Q13200,Q14203,Q15370,P19474,P20618,Q9BVA1,Q14738,O95486,O95487,O00221,Q96PU5,Q9C0C9,O43865,O75832,Q9NZ32,P46934,Q6P179,P52888,P28072,Q13309,P49720,Q8IYU2,Q93034,P62942,P28074,P30154,P60900,P25788,Q99436,P31751,P61163,Q13177,P68036,P61289,Q7Z6Z7,Q8N8S7,P28066,Q8TDB6,O43237,P49427,Q9UII4,Q9Y4B6,Q13409,P04350,Q9GZZ9,P51665,P47755,P42345,Q15008,Q96J02,Q07866,Q99460,Q16512,Q9BSL1,P48556,P09429,P62333,Q9Y496,Q16763,P63208,O00232,P17612,P17980,P25789,Q15386,Q9UJW0,Q15436,P25786,O43242,Q9UNM6,Q5T4S7,P31946,Q9Y6G9,P25787,Q9BUF5,Q9UL46,O95999,Q9BXS5 82 +Stabilization of p53 0.680963008214345 4.056473260626796 4.981926302738415e-05 0.0672324429373757 0.0014203573561072 37 P51665,P49721,Q9UNM6,P42771,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.6825708261089357 4.03300255660358 5.506868032778556e-05 0.0740481696398734 0.0015353601464237 36 P51665,P49721,Q9UNM6,P28070,P28074,Q96J02,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +Cell cycle checkpoints 0.4213507862271397 4.028846978173516 5.605108623307764e-05 0.0753181643005625 0.0015353601464237 140 Q15691,P62191,O14980,P30153,P51665,Q9UQ84,P49721,P49736,Q9UNM6,P42771,P61981,P28070,Q9Y266,Q13200,P15927,P28074,P24941,Q15008,Q99460,P06493,Q99640,P48556,P31946,P20618,P30154,P62333,Q7L590,Q92674,Q16763,Q9HBM1,O00232,Q14738,Q13535,P60900,Q9NWV8,Q9P258,O96028,Q9Y6G9,P17980,O60921,P33991,P25788,P62195,P25789,Q99436,P25787,P35244,O75832,P61289,P63104,Q9UL46,P28066,O43237,P28072,Q04917,O95067,P43034,Q6P1K2,Q13409,P27348,P25205,P40938,O75122,P49720,Q7Z460,P25786,O43242 67 +Signaling by wnt 0.5385814801734337 4.012751321238844 6.001512825504207e-05 0.0804249797193187 0.0016123295033133 86 P62191,P30153,P98170,P51665,O75436,P49721,O60493,Q9UNM6,P28070,Q13200,P28074,Q15008,Q9UBL3,Q99460,P48556,P48729,P20618,P30154,P62333,P63208,O00232,Q14738,P60900,P07737,P17980,P25788,P62195,P25789,Q99436,P31751,P25787,P49841,P40818,Q9HCK8,O75832,P61289,P63104,Q9UL46,P28066,Q9HCE1,P28072,P09497,P19784,P49720,P25786,O43242 46 +Signaling by notch4 0.6395583850267681 3.899756224771086 9.628958865581794e-05 0.1258672544154971 0.0025159730582829 41 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P63104,P28066,P28072,P49720,P25786,O43242 29 +Hedgehog ligand biogenesis 0.6493396732797427 3.897344882833192 9.72530745506628e-05 0.1270431504140826 0.0025159730582829 39 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P49720,P25786,O43242 28 +Regulation of mrna stability by proteins that bind au rich elements 0.5590310317680566 3.879175577961034 0.0001048110845931 0.1362127327791404 0.0026425752715729 62 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,P31946,P48556,Q16539,Q01105,P62333,P20618,P39687,P60900,P25788,P25789,Q99436,P25787,P04792,O75832,Q9UL46,P28066,P28072,Q9Y2L1,P49720,Q9NPI6,P25786,O43242 28 +Eukaryotic translation initiation 0.5032529772168644 3.8765914564338098 0.000105930003728 0.137562031933929 0.0026425752715729 101 P46778,P46783,Q14232,P05386,P20042,P62917,P27635,P18621,P60228,Q9UBQ5,O75822,P46781,P62701,P15880,P62269,P46776,P61247,P61513,P23588,P62841,P62847,Q9NR50,Q15056,P23396,P62861,O75821,P62241,Q14152,P84098,P62899,P08865,P06730,P62906,P39019,P39023,P83731,Q04637,P83881,P62750,P60842,O15371,P49770,P62081,O60841,P05387,P32969,Q9Y262,P62753,P62277,P62266,Q13144,P05388,P55010,P55884,P08708,P26373 56 +Uch proteinases 0.6184860648549064 3.8591809969912902 0.0001137676569296 0.146954556636652 0.0027883055566783 44 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P85037,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +Switching of origins to a post replicative state 0.5716973659316789 3.834437762368984 0.000125851832228 0.1612361463987562 0.0030312932693542 57 P62191,P51665,P49721,P49736,Q9UNM6,P28070,Q13200,P28074,Q15008,P24941,Q99460,P48556,P62333,P20618,Q16763,P63208,O00232,P60900,Q9UBD5,P17980,P33991,P25788,P62195,P25789,Q99436,P25787,O43913,O75832,P61289,Q9UL46,P28066,P28072,P25205,Q13309,P49720,P25786,O43242 37 +Synthesis of dna 0.5210316043278695 3.803521898990132 0.0001426533764343 0.180696739885354 0.0033402364647322 84 Q9Y248,P62191,P51665,P12004,P49721,P49736,Q9UNM6,P28070,P40938,Q13200,P43686,P15927,P28074,P24941,P49643,Q15008,Q99460,P40937,P48556,P20618,P62333,Q16763,P63208,O00232,P60900,Q9BRX5,Q9UBD5,P17980,P33991,Q06323,P39748,Q07864,P25788,P62195,P25789,P49642,Q99436,P25787,P35244,O43913,O00231,O75832,P61289,P28340,Q9UL46,P28066,P18858,P56282,P35251,Q9BRT9,P28072,P25205,Q13309,P49720,P25786,O43242 56 +Transcriptional regulation by runx3 0.631557910958744 3.8002176227556537 0.0001445690717885 0.1828867636126578 0.0033402364647322 40 P51665,P49721,Q9UNM6,P42771,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +Dna replication 0.5135079161185361 3.798028743696426 0.0001458514132774 0.184349467485736 0.0033402364647322 90 Q9Y248,P62191,P51665,P12004,P49721,P49736,Q9UNM6,O00716,P28070,P40938,Q13200,P43686,P15927,P28074,P24941,P49643,Q15008,Q99460,P40937,P48556,P20618,P62333,Q7L590,Q16763,P63208,O00232,P60900,Q9BRX5,Q9UBD5,P17980,P33991,Q06323,P39748,Q07864,P25788,P62195,P25789,P49642,Q99436,P25787,P35244,O43913,O00231,O75832,P61289,P28340,Q9UL46,P28066,P18858,O60684,P56282,P52294,P35251,Q9BRT9,P28072,P25205,Q13309,P49720,P25786,O43242 60 +Pten regulation 0.5293209506286588 3.7770473911401425 0.0001586985435289 0.1988599145901961 0.003575836537256 67 P51665,P98170,Q92995,P49721,Q9UNM6,P28070,Q13200,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,Q12873,O75832,Q9UL46,P46934,P28066,Q9HCE1,P28072,P49720,P25786,O43242 26 +Defective cftr causes cystic fibrosis 0.6274547831042119 3.768829019552872 0.0001640151855633 0.2047891716738105 0.003580143972374 40 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P49720,P25786,O43242 28 +Abc transporter disorders 0.6274547831042119 3.768829019552872 0.0001640151855633 0.2047891716738105 0.003580143972374 40 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P49720,P25786,O43242 28 +Antigen processing cross presentation 0.5861902121288619 3.749792921833245 0.0001769806568494 0.2190653900657811 0.0037460905699801 49 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P09429,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P28072,P49720,P25786,O43242 21 +G2 m checkpoints 0.5137972821738335 3.726461778194311 0.0001941865029626 0.2376159802877104 0.0039893903623357 84 P62191,P51665,O43242,Q9UQ84,P49721,P49736,Q9UNM6,P61981,P28070,P40938,Q13200,P15927,P28074,P24941,Q15008,Q99460,P40937,Q99640,P48556,P31946,P20618,P62333,Q7L590,O00232,Q13535,P60900,Q9NWV8,Q9UBD5,O96028,P17980,O60921,P33991,P25788,P62195,P25789,Q99436,P25787,P35244,O43913,O00231,O75832,P61289,P63104,Q9UL46,P28066,P28072,Q04917,O95067,P27348,P25205,P49720,P25786,P06493 53 +Beta catenin independent wnt signaling 0.5713652842642318 3.7203722391163674 0.000198929357065 0.2426516480979254 0.0040275987220262 53 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P07737,P25788,P25789,Q99436,P25787,O75832,P28066,Q9HCE1,P28072,P49720,P25786,O43242 21 +Apc c mediated degradation of cell cycle proteins 0.5472942556690018 3.643143793146614 0.0002693282794461 0.3136051838627348 0.0053750229483752 58 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,P24941,P06493,Q99460,P48556,P62333,P20618,Q16763,P63208,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q13309,O14965,P49720,P25786,O43242 33 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5687976027624012 3.6246630396935022 0.0002893384450373 0.3325323105109214 0.0056930395453116 50 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,Q16763,O00232,P60900,P17980,P25788,P25789,Q99436,P25787,O75832,P61289,Q9UL46,P28066,P28072,Q13309,O14965,P49720,P25786,O43242 29 +Nervous system development 0.4364223678837162 3.6180713548254175 0.0002968065752069 0.3394618064619432 0.0057588720217231 221 P49721,Q06124,P28070,Q13200,Q15370,Q16539,P20618,Q9BVA1,P84098,Q16850,O75832,Q00535,P05387,P32969,P28072,Q9UIW2,P49720,Q7Z460,P62917,P36507,P15311,P15880,P28074,P61247,P61513,P60900,P07737,Q16555,Q13740,P25788,P08238,P62899,Q99436,P39019,P83731,Q13177,Q04637,P62750,P61289,Q8N8S7,P28066,P62081,P62277,P62266,P05388,O75122,P04350,P46778,P51665,P46783,P27635,P18621,Q12955,Q15008,Q99460,Q16512,Q00169,P48556,P62333,P62841,O00232,P17612,P17980,P23396,P62861,P62241,P62195,P25789,P62906,P39023,P83881,P62495,P62753,P09497,P19784,P08708,P26373,P25786,P07900,O43242,O15144,P62191,P26038,Q9UNM6,P46781,P62269,P35080,P46776,Q02750,P62847,P08865,P25787,P49841,O75116,O00231,Q9BUF5,P35241,Q9UL46 98 +Eukaryotic translation elongation 0.5083255996787597 3.6083249377773674 0.0003081803580176 0.3498773970227828 0.0058976432897342 77 P46778,P24534,P46783,P05386,P27635,P62917,P13639,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,Q05639,P62861,P62241,P08865,P84098,P62899,P26641,P62906,P39019,P39023,P29692,P83731,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P26373 40 +Intracellular signaling by second messengers 0.4867421894106696 3.5424972902156937 0.0003963574950525 0.4252506138843115 0.0073828189411781 93 P30153,P98170,P51665,P42345,Q92995,P49721,Q9UNM6,Q06124,P28070,Q13200,P28074,Q15008,Q96B36,Q99460,P51617,P48556,Q9HC52,P20618,P30154,P62333,O00232,Q14738,P60900,P17612,P17980,P25788,O43815,P25789,P78356,Q99436,P31751,P25787,Q12873,P49841,O43865,O75832,P61289,Q9UL46,P46934,P28066,Q9HCE1,P28072,P49720,P25786,O43242 45 +Abc family proteins mediated transport 0.5526894551350818 3.531341515427877 0.0004134575462919 0.4388234020674482 0.0076000025285509 52 P51665,P20042,P49721,Q8NE71,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P62333,P20618,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P25787,P40855,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P49720,P25786,O43242 31 +Signaling by interleukins 0.4563292718252976 3.5169793626286343 0.0004364877173268 0.4565983030353667 0.0078980066556109 110 Q8IV63,P62191,P26038,P30153,P51665,P49721,Q9UNM6,Q06124,P28070,Q13200,P28074,Q15008,P46108,P51617,Q99460,Q00169,P48556,P09429,Q16539,Q02750,P20618,P30154,P62333,P04083,Q13126,P63208,O00232,Q14738,P60900,Q53EL6,P14174,P17612,P17980,P25788,P62195,P25789,P52597,Q99436,P46109,P25787,P37837,Q13177,O00170,O75832,P61289,Q99439,P63104,Q9UL46,P28066,P28072,P05388,P51452,P11233,P49720,P25786,P07900,O43242 57 +Transcriptional regulation by runx1 0.506645486096541 3.5142625345622243 0.0004409767495616 0.4599968951606214 0.0078980066556109 66 P51665,P49721,Q9UNM6,Q06124,P28070,Q13200,P28074,Q96J02,Q9UBL3,P48556,Q00534,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9C005,Q9UL46,P28066,Q9HCE1,P28072,P49720,P25786,O43242 27 +Response of eif2ak4 gcn2 to amino acid deficiency 0.492222228060398 3.4327795858335532 0.000597427562458 0.5660629113858872 0.0104325788094239 76 P46778,P46783,P05386,P20042,P62917,P27635,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62861,P08865,P62241,P84098,P62899,P62906,P39019,P39023,P83731,Q92616,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P08243,P26373 38 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.5413627558051899 3.4076100233584956 0.0006553448233175 0.5998103978780898 0.0111648380265193 51 P46783,P20042,P60228,Q9UBQ5,P46781,O75822,P62701,P15880,P62269,P61247,P23588,P62841,P62847,Q15056,P23396,P62861,O75821,P62241,P08865,P06730,Q14152,P39019,Q04637,P60842,O15371,P62081,Q9Y262,P62753,P62277,P62266,P55884,P08708 32 +Signaling by notch 0.5180694629501283 3.370902881439611 0.0007492226547596 0.6490306344150146 0.0126104102252916 58 P51665,P49721,Q9UNM6,O00716,P28070,P28074,Q96J02,P67809,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,Q9HCE1,P28072,P49720,P25786,O43242 24 +Nonsense mediated decay nmd 0.4726336164772831 3.295692606778218 0.0009817937711613 0.746461510912945 0.0157651252679589 86 P46778,P30153,P46783,P05386,P27635,P62917,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62861,P62241,P08865,P84098,P62899,P62906,P39019,P39023,P83731,Q04637,P83881,P62750,P62495,P62081,P05387,Q96Q15,P63151,P32969,Q9HAU5,P62753,P62277,P62266,P05388,Q9NPI6,P08708,P26373 42 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5969491969130435 3.290834377240449 0.0009989070632003 0.7524569086793541 0.015857649628306 32 P47755,P25685,P07900,Q14203,Q9BVA1,P31689,Q9Y6G9,P08238,P31948,P61163,Q9BUF5,P04150,Q9NZ32,Q02790,O43237,O60884,Q9UJW0,Q13409,P04350 19 +Mapk family signaling cascades 0.4565026072753355 3.234891651572647 0.001216888990899 0.8175043810722818 0.0189303502001205 96 P62191,P30153,P51665,O43242,P36507,P49721,P25685,P30086,Q9UNM6,Q06124,P28070,Q13200,P28074,Q15008,Q99460,P53041,Q16512,P48556,P31946,Q02750,P20618,P30154,P62333,O00232,Q14738,P60900,P17612,P17980,O43924,P25788,P62195,P25789,Q99436,P25787,Q13177,P04792,O75832,P61289,Q9UL46,P28066,Q9HCE1,P28072,P10398,P07196,P49720,P25786,P06493 47 +S phase 0.4521726653223787 3.2313879269711108 0.0012319062310981 0.8212976872666918 0.0189303502001205 99 Q9Y248,P62191,P51665,P49721,P49736,Q9UNM6,P28070,P40938,Q13200,P15927,P28074,P24941,Q15008,P49643,Q99460,P40937,P48556,P20618,P62333,Q16763,P63208,O00232,P60900,Q9UBD5,P17980,P33991,P39748,P25788,Q07864,P62195,P25789,P49642,Q99436,P31751,P25787,P49841,P35244,O43913,O00231,O75832,P61289,Q9UL46,P28066,P18858,P56282,Q9BRT9,P28072,P25205,Q13309,P49720,P25786,O43242 52 +Separation of sister chromatids 0.4461861964396996 3.231107587570386 0.0012331151526205 0.8215996081535462 0.0189303502001205 103 Q15691,P30153,P51665,P49721,Q9UNM6,P28070,Q9Y266,Q13200,P28074,Q15008,Q99460,P48556,P20618,Q9BVA1,P30154,P62333,Q92674,Q16763,Q9HBM1,O00232,Q14738,P60900,Q14674,Q9P258,Q9Y6G9,P17980,P25788,P25789,Q99436,P25787,Q9BUF5,O75832,P61289,Q9UL46,P28066,O43237,P28072,Q13409,P43034,Q6P1K2,O75122,P49720,Q7Z460,P25786,P04350,O43242 46 +Selenoamino acid metabolism 0.4458276537406253 3.018578113721195 0.0025396392103966 0.9713438953466376 0.0326589332517183 89 P46778,P46783,P27635,P62917,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62861,P62241,P84098,P62899,P00390,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P05387,P32969,P49591,P62753,P62277,P62266,P05388,P08708,P26373 35 +Ub specific processing proteases 0.4503915210591709 2.9984893027572075 0.0027132168095689 0.9775286753461476 0.0332488059909455 80 P51665,Q92995,P49721,O60493,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,Q96K76,P20618,P62333,O00232,P60900,Q9NZL9,P17980,P25788,P62195,P25789,Q99436,Q96FW1,P25787,Q96RU2,P40818,Q13107,O75832,P61289,Q9UL46,Q13546,P28066,P28072,Q13309,O94966,P49720,P25786,O43242 38 +Apoptosis 0.4386178806619653 2.9337466465720605 0.0033489745043764 0.9907798966783236 0.0371310903382053 89 P62191,P51665,P98170,P49721,Q9UNM6,P42771,P28070,Q13200,P28074,Q96E52,Q15008,Q99460,P48556,P31946,P09429,P20618,P62333,O00232,P60900,P17980,P25788,P62195,P25789,Q99436,P31751,P25787,Q13177,O75832,P61289,P63104,Q9UL46,P28066,Q13546,P52294,P28072,Q04917,P27348,P49720,P25786,O43242 40 +Diseases of signal transduction by growth factor receptors and second messengers 0.3629567229216566 2.9252670174780446 0.0034416077602958 0.9919026511294506 0.037488803354827 156 P62191,P62942,P49589,P30153,P51665,P42345,P51114,P26038,P36507,P49721,P30086,Q9UNM6,P42224,Q06124,P28070,Q13200,P28074,Q14203,Q15008,Q07866,Q96B36,Q99460,P31939,O95429,P48556,P31946,P48729,Q02750,P20618,P30154,P62333,Q9HC35,Q16543,P63208,O00232,Q14738,P60900,P06753,P17980,P25788,P62195,P25789,O43815,P26641,Q99436,P31751,P67936,P25787,Q8IWJ2,P49841,Q92734,O00203,O75832,P61289,Q9UL46,P28066,Q9UBV2,P28072,P62753,P10398,P13984,P49720,P25786,P07900,O43242 65 +Cilium assembly 0.4393150618889416 2.846908359538776 0.0044146068608761 0.9979313496226584 0.0460361076371105 67 Q15691,Q9NVX0,P30153,P17987,Q9H6D7,P61981,P07900,Q14203,P06493,Q6NUS6,Q96CS2,O75695,Q92973,Q9UPT5,Q9BVA1,P18085,Q9Y496,P68371,P50991,P78371,Q96KP1,Q92538,Q9BT25,P07437,P17612,A0AVF1,Q15019,O43924,Q14204,O75935,Q9BW83,Q9NQ48,P41208,P36405,P61163,P23258,Q9BUF5,P62258,P49368,A6NIH7,Q8IYI6,Q15154,Q13409,P43034,Q8TAG9,Q15051,Q7Z460,O94927,P04350,Q96A65 50 +Recruitment of mitotic centrosome proteins and complexes 0.5353557729831149 2.842505769704448 0.0044760420927099 0.9981022135882964 0.0463187466927092 33 Q15691,P30153,Q9H6D7,P61981,P07900,Q14203,Q96CS2,P07437,P17612,O75935,P41208,P61163,P23258,P62258,Q13409,P43034,Q7Z460,O94927,P04350,P06493 20 +Interconversion of nucleotide di and triphosphates 0.6870808101720263 2.831731770134463 0.0046296667516017 0.9984702674167384 0.047556209205791 17 Q9H773,P15531,P00390,P33316,Q9Y3D8,P23919,P22392,Q9NRF8,P17812 9 +Programmed cell death 0.4163865775389933 2.8193138350300924 0.0048126438591382 0.9988167541573374 0.0483688019511953 101 P51665,P98170,P49721,Q9UNM6,P42771,P28070,P28074,Q96E52,P48556,P31946,P09429,P20618,P62333,Q16543,P60900,P25788,P25789,Q99436,P25787,O75832,P28066,P52294,P28072,P49720,P25786,O43242 26 +Mitotic metaphase and anaphase 0.3442182429755728 2.813956753613744 0.0048935811235668 0.9989438390341536 0.0488309487830207 137 Q15691,Q9UN37,P30153,P51665,P49721,Q9UNM6,P28070,Q9Y266,Q13200,P28074,P48556,Q92973,P20618,Q9BVA1,P30154,P62333,Q92674,Q9HBM1,P60900,Q14674,Q9Y6G9,P25788,P25789,P53990,Q99436,P25787,Q9BUF5,O75832,Q9UL46,P28066,O43237,P63151,P28072,O95067,Q6P1K2,O75122,P49720,P25786,O43242 39 +Anchoring of the basal body to the plasma membrane 0.5217669168758409 2.781454320370655 0.0054115945812078 0.9994897080530122 0.0528671162933385 35 Q15691,P30153,Q9H6D7,P04350,P61981,Q14203,Q96CS2,P07437,P17612,Q15019,O75935,P41208,P61163,P23258,Q13409,P43034,Q15051,Q7Z460,O94927,P07900,P06493 21 +Deubiquitination 0.4075618078739829 2.690643925375768 0.0071314266277555 0.9999545226693582 0.0655434407827271 100 Q15018,P51665,Q92995,P49721,O60493,Q9UNM6,P28070,Q13200,P28074,Q15008,Q99460,P48556,P85037,Q96K76,P20618,P62333,O00232,P60900,Q9NWV8,Q9NZL9,P17980,P25788,P62195,P25789,Q99436,Q96FW1,P25787,Q96RU2,P40818,Q13107,Q92783,O75832,P61289,Q9UL46,Q13546,P28066,P54727,P28072,Q13309,P54725,O94966,P49720,P25786,O43242 44 +Aurka activation by tpx2 0.5118332417774318 2.6770448339878543 0.0074274695280505 0.9999700176346272 0.0678181368018729 34 O75330,Q15691,P30153,Q9H6D7,P04350,P61981,Q14203,Q96CS2,P07437,P17612,O75935,P41208,P61163,P23258,Q13409,P43034,O14965,Q7Z460,O94927,P07900,P06493 21 +Regulation of plk1 activity at g2 m transition 0.4937317986584663 2.6530306853164585 0.00797726184582 0.9999861734908516 0.0723651610299389 39 Q15691,P30153,Q9H6D7,P61981,P07900,Q14203,Q96CS2,P63208,P07437,P17612,O75935,P41208,P61163,P23258,O95067,P43034,Q13409,O14965,Q7Z460,O94927,P04350,P06493 22 +Recruitment of numa to mitotic centrosomes 0.4972767962495324 2.6295333555220513 0.0085502143589744 0.9999938312052002 0.0737324040709089 37 Q15691,P30153,Q9H6D7,P61981,P07900,Q14203,Q96CS2,Q9BVA1,P07437,P17612,O75935,P41208,P61163,P23258,Q9BUF5,P62258,Q13409,P43034,Q7Z460,O94927,P04350,P06493 22 +Cytoprotection by hmox1 0.4220973094393164 2.5982731115142403 0.009369394044741 0.9999980559699708 0.0788496595211036 65 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,P53004,O75832,P28066,P28072,Q86X55,P49720,P25786,O43242 21 +Hiv infection 0.3294634771640612 2.5612258664454406 0.010430352053997 0.9999995649155912 0.0857129518790224 137 Q93034,Q9UN37,P62191,P51665,O75351,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,P62826,Q99460,Q15370,P48556,Q9H9H4,P20618,P62333,Q08945,Q9Y5B9,Q9NZZ3,P63208,O00232,P60900,P13010,P17980,Q96PU5,P25788,P39748,P62195,P25789,Q99436,P25787,Q13177,O75832,P61289,Q9UL46,P28066,P18858,Q8WX92,O60942,P52294,P55199,Q9BXS5,Q14241,P28072,P29083,P23193,P13984,P49720,P25786,O43242 52 +Metabolism of nucleotides 0.4556250376523822 2.497839219844157 0.0124952851668305 0.9999999764911468 0.1001067673653895 45 Q9H773,O43598,P15531,P11172,P00390,P00491,P49915,P33316,Q9Y3Z3,P04183,Q06203,Q9Y3D8,P23919,Q9UKK9,Q9P2T1,P22392,Q9NRF8,P17812 18 +Cellular response to chemical stress 0.4023129461742651 2.4325281883922596 0.0149938243727472 0.999999999317319 0.1144610527252888 75 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,P00390,Q99436,P25787,P53004,O75832,Q9UL46,P28066,P28072,Q86X55,P49720,P25786,O43242 23 +Negative regulation of mapk pathway 0.6554862828962281 2.4073556459274927 0.0160685132757922 0.999999999851438 0.1200412462368011 14 Q02750,P30154,P30153,P36507,P30086,P10398,Q14738,P31946 8 +Cellular response to starvation 0.393164721031475 2.3840069596583273 0.0171252784954241 0.9999999999668916 0.1252566181052748 89 P46778,P08243,P46783,P42345,P27635,P20042,P62917,P18621,P46781,P15880,P62269,P61247,P61513,P62841,P62847,P23396,P62861,P62241,P84098,P62899,P62906,P39019,P39023,P83731,Q92616,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P26373 36 +Cyclin d associated events in g1 0.6563266862722967 2.319383944042592 0.0203742274481981 0.9999999999996756 0.1409049294313507 13 Q00534,P63151,P30153,P30154,O00716,P42771,Q13309,P24941 8 +Metabolism of cofactors 0.9293873114599968 2.312643267528948 0.0207422605813294 0.999999999999808 0.1409858886718819 4 P00374,O75874 2 +Copi independent golgi to er retrograde traffic 0.5219131817818509 2.305180789607083 0.0211564502965824 0.9999999999998938 0.141414167771893 27 Q9BVA1,Q15102,Q9UJW0,P61163,P04350,Q13409,P43034,Q9BUF5,Q14203,Q9Y6G9,Q9NZ32,Q15042,Q8TD16,O43237 14 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5896820275068063 2.2943412471475564 0.0217709050770946 0.9999999999999558 0.1434620490221757 18 Q9NQP4,O15212,Q9BVA1,Q9UHV9,Q99471,P61758,Q9BUF5,P04350 8 +Erks are inactivated 0.8211805712745626 2.272717700424428 0.0230431972965106 0.9999999999999928 0.1504268533795575 6 Q8IV63,P51452,P30154,P30153 4 +Developmental biology 0.3706845491892948 2.253628514432497 0.0242195479372722 0.9999999999999988 0.1537941294016785 266 P49721,Q06124,P28070,Q13200,Q9UBL3,Q15370,Q16539,P20618,Q9BVA1,O60271,P84098,Q16850,O75832,Q00535,P05387,P32969,P28072,Q9UIW2,Q86X55,P49720,Q7Z460,P62917,P36507,P15311,P15880,P28074,P24941,P61247,P61513,P60900,P07737,Q16555,Q13740,O75448,P25788,P08238,P62899,Q99436,P31751,P39019,P83731,Q13177,Q04637,P62750,P61289,Q8N8S7,P28066,P62081,P62277,P62266,P05388,O75122,P04350,Q96EK7,P46778,P51665,P46783,P27635,P18621,Q12955,Q15008,Q99460,Q16512,Q00169,P48556,O60244,P62333,P62841,O00232,P17612,P17980,P23396,P62861,P62241,P62195,P25789,P62906,P39023,P83881,P62495,P62753,P09497,P19784,P08708,P26373,P25786,P07900,O43242,O15144,P62191,P26038,Q9UNM6,P46781,P62269,P35080,P46776,Q02750,P62847,Q15648,Q9ULK4,P08865,P25787,P49841,O75116,O00231,Q9BUF5,P35241,Q9UL46 108 +Platelet sensitization by ldl 0.8127928597742782 2.2364487191658124 0.0253223928609456 0.9999999999999998 0.1586340037073588 6 Q16539,Q06124,P30154,P30153 4 +Metabolism of folate and pterines 0.6961300456550743 2.234528738530848 0.0254483037858765 0.9999999999999998 0.1587110731645964 9 P00374 1 +Transcriptional activation of mitochondrial biogenesis 0.6436120532494065 2.1644380751750227 0.0304307443258344 1.0 0.1832403009620291 12 P48735 1 +Cholesterol biosynthesis 0.5554505705382672 2.0471134463347127 0.0406469470411248 1.0 0.2280473293833388 17 Q15125,Q9UBM7,Q16850 3 +Nicotinate metabolism 0.8597186169621526 2.0330109751882564 0.0420514141892649 1.0 0.2304034213549782 4 Q9BQG2 1 +Activation of atr in response to replication stress 0.5236436538572743 2.030553134135385 0.0423003459731714 1.0 0.2308343098614082 22 P33991,Q7L590,P35244,O43913,P49736,Q13535,P40938,P40937,P15927,Q9UBD5,P24941,P25205,P30307,O60921 14 +Netrin 1 signaling 0.6287662741018748 2.016916072250313 0.0437042725183589 1.0 0.2348264181082594 11 Q16539,Q06124,Q16512,Q00169 4 +Retrograde transport at the trans golgi network 0.5437449299132597 2.007102309955109 0.0447387703303774 1.0 0.2394638396610623 18 Q7Z6M1,Q5VZE5,Q9UP83,Q9UID3,P20645 5 +Darpp 32 events 0.6497117658337848 1.999174308345528 0.0455894973261763 1.0 0.2410069220400971 9 Q14738,P30154,P30153,Q00535 4 +Signaling by mras complex mutants 0.848297886169413 1.986440745708349 0.0469844061251654 1.0 0.2449149826748361 4 P10398 1 +Dna damage recognition in gg ner 0.5433162369008511 1.97130570506906 0.0486889192023096 1.0 0.2507733328661821 17 Q9UNS2,P41208,Q7L5N1,P61201,P54725,Q9UBW8,Q92905 7 +Aggrephagy 0.5632400403660823 1.9692059297978255 0.0489294482320432 1.0 0.2507733328661821 15 Q99497,Q9BVA1,P04350,Q13409,Q9BUF5,Q9Y6G9,Q14204,O43237,P07900 9 +Oxidative stress induced senescence 0.5758341718489306 1.954937182964142 0.0505904851138845 1.0 0.2574133083722703 14 Q16539,Q00534,Q9HCE1,O00716,P42771 5 +Hsf1 activation 0.5382279180338211 1.909016211760032 0.0562600003586433 1.0 0.2710180017276714 16 P08238,P27694,P35244,P25685,Q92598,P04792,P15927,Q02790,P62258,O75190,P07900 11 +Synthesis of pa 0.6303665449459067 1.899356589966258 0.0575176070048728 1.0 0.2751784143349567 9 Q8N2A8 1 +Glycogen synthesis 0.6924907731989027 1.8956712015355923 0.0580035356704309 1.0 0.2762110875787796 7 P13807,P46976,Q96G03,P36871 4 +Synthesis of pe 0.962987451555906 1.8881754225728495 0.0590024041448149 1.0 0.2768467540314822 3 P35790 1 +Glutathione conjugation 0.5643355892652528 1.8878595146851256 0.0590448128797502 1.0 0.2768467540314822 14 Q96KP4,Q8WUX2,P28161,P21266 4 +Activation of bad and translocation to mitochondria 0.64530289727832 1.8709865835093429 0.0613469406627684 1.0 0.2820024900737176 8 P31751,P61981,Q04917,P27348,P62258,P63104,P31946 7 +Negative regulation of nmda receptor mediated neuronal transmission 0.6872599093639198 1.8708467494160228 0.0613663256853329 1.0 0.2820024900737176 7 Q14012 1 +Srp dependent cotranslational protein targeting to membrane 0.3518167038188726 1.868645414632094 0.0616721629424619 1.0 0.2824787266577682 90 P46778,P46783,P27635,P62917,P18621,P46781,P15880,P62269,P61247,P61513,P62841,P62847,P23396,P62861,P62241,P84098,P62899,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,O76094,P08708,P26373 33 +Myoclonic epilepsy of lafora 0.9348524685948008 1.8589243280547536 0.063037865190942 1.0 0.2877905152671437 2 P46976 1 +Cytokine signaling in immune system 0.3148212891702993 1.8435350777744044 0.0652509250780384 1.0 0.2950017551262773 181 Q93034,Q8IV63,Q13325,P62191,P26038,P30153,P51665,P61081,P49721,Q9UNM6,P42224,Q06124,P28070,Q13200,P28074,Q15008,Q13526,P46108,P51617,Q15370,Q99460,Q00169,P48556,P09429,Q16539,P19474,Q02750,P20618,P30154,P62333,P04083,Q9Y3Z3,Q13126,P63208,O00232,Q14738,P60900,Q53EL6,P14174,P17612,P17980,P19525,P25788,P62195,P25789,P52597,Q99436,P31751,P46109,P25787,P37837,Q13177,Q04637,O00170,O75832,P61289,Q99439,P63104,P46934,Q9UL46,P28066,P52294,Q9UII4,P28072,P05388,P51452,O00505,P11233,P49720,P25786,P07900,O43242 72 +Ctla4 inhibitory signaling 0.6192358523665541 1.841483733730908 0.0655507021486265 1.0 0.2954010674246171 9 Q14738,Q06124,P30154,P30153 4 +Signalling to erks 0.6055646187027063 1.8297050452152177 0.0672940560777357 1.0 0.2982475862868307 10 Q16539,Q02750,P46109,P46108,P31946 5 +Phase ii conjugation of compounds 0.4416999288546525 1.82857497039265 0.0674633051300204 1.0 0.2982475862868307 29 Q8WUX2,Q9UI30,P28161,P21266,Q9HBK9,Q9NZL9 6 +Metabolism of vitamins and cofactors 0.3792784745474768 1.8258933095871104 0.067866334175338 1.0 0.2990828670124519 49 P00374,O75874,P35270,Q9BQG2,P43490 5 +Toll like receptor cascades 0.4407653240298634 1.821101596012654 0.0685914147295974 1.0 0.3013276930102125 29 P09429,Q6SZW1,Q8IV63,Q16539,Q15075,Q02750,Q99570,P30153,P30154,Q8NEB9,Q14738,Q06124,P51452,Q13546 14 +Translesion synthesis by polk 0.6009870019540609 1.8053046214668784 0.0710270268624404 1.0 0.3081514177851842 10 P35251,P12004,P35244,P40938,P40937,P15927 6 +Activation of the pre replicative complex 0.4947305957770134 1.7939782102781392 0.0728166468016828 1.0 0.3113889995481586 21 Q07864,P49642,Q7L590,P35244,O43913,P49736,Q9UBD5,P15927,P25205,P24941,P49643,P33991 12 +Downregulation of erbb4 signaling 0.9190768331872669 1.7935328581781085 0.0728877615263048 1.0 0.3113889995481586 2 P46934 1 +Global genome nucleotide excision repair gg ner 0.389966577780088 1.7916084646200905 0.0731957062699455 1.0 0.3117512245704692 42 Q99627,P12004,P40938,P40937,P15927,P61201,P18074,Q07864,P41208,P35244,Q86WJ1,Q7L5N1,P28340,P27694,Q9UBW8,P18858,P56282,P35251,Q9UNS2,P54727,P54725,Q92905 22 +Nucleotide salvage 0.627743634767357 1.7822210985099385 0.0747131834953611 1.0 0.3162858101303622 8 P00491,P55263,P04183,P00492,P07741,Q01433,Q9P2T1 7 +Metabolism of amino acids and derivatives 0.3166202937167677 1.776399403343201 0.0756671093859278 1.0 0.3183944331690997 192 P46778,P62191,P51665,P46783,P27635,P62917,P19623,P49721,P18621,P16930,Q9UNM6,P46781,P28070,P15880,Q13200,P28074,Q15008,P62269,P61457,Q99460,P48556,P61247,P61513,P20618,P62333,P62841,P62847,Q13126,O00232,Q9BV20,P60900,P17980,P23396,P62861,P25788,P62241,P62195,P84098,P62899,P25789,Q99436,P62906,P00390,P39019,P39023,P25787,P83731,P83881,O75832,P62750,P61289,Q9UL46,P28066,P17174,O14874,P62081,O75600,P05387,P12277,P32969,Q96SZ5,P49591,P28072,Q6QHF9,P62753,P62277,P62266,P05388,P08708,P49720,P08243,P26373,P25786,O43242 74 +Raf activation 0.5447587207757094 1.772715921525103 0.0762757914954075 1.0 0.3199381242279789 14 Q02750,P30154,P30153,Q14738,P10398,P31946 6 +Methylation 0.6251169943723304 1.7688826557812545 0.0769134591870073 1.0 0.3199381242279789 8 Q9UI30,Q9HBK9 2 +Intra golgi and retrograde golgi to er traffic 0.341454435901026 1.768576130411189 0.07696463706397 1.0 0.3199381242279789 95 P48444,P47755,Q7Z6M1,Q9UP83,O15260,Q9UID3,Q14203,Q07866,O00461,P24390,P83436,Q9BVA1,Q9Y496,Q9Y678,O60664,Q9Y6G9,Q8TD16,O95721,P35606,P53621,Q8IWJ2,P61923,P61163,Q5VZE5,Q9BUF5,Q9NZ32,Q16706,Q15042,P20645,O43237,Q9UBF2,Q9UJW0,Q13409,P43034,Q8N6T3,A2RRP1,Q15102,P04350 38 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5938754134320627 1.76729366193758 0.077179060747909 1.0 0.3199381242279789 10 Q04917,P61981,P27348,P30307,P62258,P63104,P31946,P06493 8 +Hsf1 dependent transactivation 0.5083889680317418 1.750103541622145 0.0801004487591705 1.0 0.3262400201649016 17 Q96B36,P08238,P42345,P25685,P04792,Q02790,O75190 7 +Glycogen metabolism 0.5790861652172652 1.7482478571238664 0.0804211179514118 1.0 0.3264426369393299 11 P13807,P06737,Q96G03,P36871,P35573,P46976,Q16851 7 +Regulation of pten localization 0.925465681765532 1.7439633631630616 0.0811654785122033 1.0 0.3268200861296675 3 P46934 1 +Post chaperonin tubulin folding pathway 0.5773690099633454 1.738846257355394 0.0820618095392138 1.0 0.3284823722816095 11 Q9BVA1,Q15813,Q15814,Q9BUF5,P04350 5 +Disorders of transmembrane transporters 0.3430226520171931 1.73339142043129 0.0830261214836982 1.0 0.3291136404940041 72 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,P28066,P28072,P49720,P25786,O43242 19 +E2f mediated regulation of dna replication 0.575992512355435 1.731304643919904 0.0833974436183804 1.0 0.3291136404940041 11 P49642,P30153,P30154,Q9UBD5,P49643,P06493 6 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6984944548336475 1.7283693657692762 0.0839220240834253 1.0 0.329770020813549 6 P49642,P30153,P30154 3 +Fanconi anemia pathway 0.5960996481641582 1.7202144783648403 0.0853934621919123 1.0 0.3313740741169487 9 Q9NVI1,Q16658,Q9BXW9,P35244,Q13535,P15927 6 +Recycling of eif2 gdp 0.6551000433002008 1.717016080021255 0.0859762339924594 1.0 0.3327113542589082 7 P49770,Q13144,Q9NR50,Q14232 4 +Signaling by erbb4 0.6144148216069532 1.7143801280795683 0.08645893570083 1.0 0.3336550640167393 8 P16949,P46934,Q96J02 3 +Signaling by ntrks 0.3979175314229727 1.7073038534541158 0.0877655902552148 1.0 0.3359137796891371 34 Q16539,Q8IV63,Q02750,P30154,P30153,P46109,Q00535,Q14738,Q06124,P51452,P46108,P31946,Q8WX92 13 +Regulation of tp53 expression and degradation 0.5578292775255088 1.6928265245192065 0.0904884922875144 1.0 0.3403969900389931 12 P30154,P30153,Q9UER7,P42345,P31751,P42771,P24941 7 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.910169463740326 1.6848342706619936 0.0920205508943117 1.0 0.3437238224581643 3 P00374 1 +Cytosolic trna aminoacylation 0.465586806030215 1.6706618867643772 0.0947884810448775 1.0 0.3504245197823579 23 P54577,Q9P2J5,Q15181,P49589,Q9Y285,P41250,P26639,P49591,P26640,O43324,P23381,P49588,Q9NSD9,Q13155,O43776 15 +Regulation of tp53 activity through phosphorylation 0.3801607545840655 1.653836225113557 0.0981607934484962 1.0 0.3585508338528775 40 Q16539,Q9UQ84,P35244,Q13526,O60921 5 +Myd88 independent tlr4 cascade 0.4679894664558212 1.648136442963289 0.0993246754846706 1.0 0.3604066796158047 22 P09429,Q6SZW1,Q8IV63,Q16539,Q02750,P30154,P30153,Q14738,Q06124,P51452,Q13546 11 +Cyclin a b1 b2 associated events during g2 m transition 0.5496479365476943 1.6468246141093843 0.0995941005331966 1.0 0.3604480788727349 12 P63151,P30153,P30154,O95067,P24941,Q99640,P06493 7 +Oncogene induced senescence 0.599762003536752 1.6393723651586978 0.1011357333366178 1.0 0.362437824692476 8 P42771,Q9HCE1,Q00534 3 +Glutathione synthesis and recycling 0.6789490945520363 1.639151842527127 0.1011816403937477 1.0 0.362437824692476 6 Q96KP4,Q8WUX2 2 +Telomere c strand synthesis initiation 0.7273946063553898 1.6325492801568002 0.1025638259375032 1.0 0.3664492706769616 5 Q9NYB0,P49642 2 +Nod1 2 signaling pathway 0.5958244041178667 1.619144121045751 0.1054162576018866 1.0 0.373068158121633 8 Q16539,Q96J02 2 +Dna strand elongation 0.4072863235585436 1.6152904482529171 0.1062478111689402 1.0 0.3738745395541801 30 Q9Y248,P28340,P35251,P49642,Q9BRT9,P12004,P35244,P49736,P40938,P40937,P15927,Q9BRX5,P25205,P49643,P33991,P18858,P39748 17 +Formation of tubulin folding intermediates by cct tric 0.5302320484135615 1.6091430035438108 0.1075850758981888 1.0 0.3755444402914677 13 Q9BVA1,P17987,P68371,P50991,P78371,P40227,P04350,Q9BUF5,P48643,P49368 10 +Glycerophospholipid biosynthesis 0.3981866056565942 1.607281067897209 0.1079927254225747 1.0 0.3755444402914677 31 Q8N2A8,P35790,Q9NPH0 3 +Rho gtpases activate nadph oxidases 0.5934524189729886 1.606944813837464 0.1080664745863779 1.0 0.3755444402914677 8 Q16539,Q13526 2 +M phase 0.3081094718052074 1.597999281492414 0.110043136998077 1.0 0.3814646709337805 195 Q15691,Q9UN37,P62191,P30153,P51665,O14980,O43768,Q9H6D7,P49721,Q9UNM6,P28070,Q9Y266,Q13200,P28074,Q14203,P62826,Q15008,Q99460,P06493,P07900,P48556,Q96CS2,Q92973,Q01105,P20618,Q9BVA1,P30154,Q9HC35,P62333,Q92674,Q16763,Q9HBM1,O00232,Q14738,P60900,Q14674,Q9P258,Q9Y6G9,P07437,P17612,P17980,P25788,P62195,P25789,P53990,Q99436,P25787,P41208,P61163,Q9BPX3,Q9BUF5,O75832,P61289,Q9UL46,P28066,O43237,Q99986,O60763,P63151,Q9UPP1,P28072,P42695,O95067,P43034,Q6P1K2,Q13409,P25786,P19784,O75122,P49720,Q7Z460,O94927,P04350,O43242 74 +Mismatch repair 0.5404254210860002 1.5947923444168977 0.1107586795677448 1.0 0.3820969457974451 12 Q9UQ84 1 +Host interactions of hiv factors 0.3303855299656222 1.5912817281268845 0.1115461870089511 1.0 0.3838177912598639 90 P51665,P49721,Q9UNM6,P28070,Q13200,P28074,P48556,P20618,P62333,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P28066,P52294,P28072,Q9BXS5,P49720,P25786,O43242 23 +Pcna dependent long patch base excision repair 0.4743408482092861 1.588044906199662 0.1122761850303621 1.0 0.3853804188879999 19 Q07864,P56282,P35251,P12004,P35244,P27695,P40938,P40937,P15927,P28340,P18858,P39748 12 +Formation of incision complex in gg ner 0.4998262061536069 1.5831167105630095 0.1133948655172121 1.0 0.387698775399355 15 P18074,P41208,P35244,P54727,Q86WJ1,P15927,P54725,P27694 8 +Uptake and actions of bacterial toxins 0.5868717650952275 1.5730470174095044 0.1157079316950953 1.0 0.387698775399355 8 P36507,P08238,Q02750,P07900 4 +Homologous dna pairing and strand exchange 0.4765807294635614 1.5729653761778108 0.1157268356059635 1.0 0.387698775399355 18 Q9UQ84,P35244,O60921 3 +Maturation of sars cov 2 nucleoprotein 0.7122914787127291 1.566962383619428 0.1171234844149382 1.0 0.3905047917128132 5 P49841,P48729,Q96SB4 3 +Pentose phosphate pathway 0.5847831635322274 1.5622726078634497 0.1182237821247285 1.0 0.3932348181624898 8 P11908,P37837,Q96G03,P60891 4 +Hdr through single strand annealing ssa 0.473322691055634 1.551554399198068 0.1207688814433516 1.0 0.3962848515310784 18 Q9UQ84,P35244,O60921 3 +Sealing of the nuclear envelope ne by escrt iii 0.5431413568860916 1.5500628301710515 0.1211264363663353 1.0 0.3962848515310784 11 Q9UN37,P53990,Q9BVA1,Q9BUF5 4 +Prolonged erk activation events 0.6177581353257059 1.5360740558421646 0.1245202184967497 1.0 0.4017430606003682 7 P46108,P31946,Q02750,P46109 4 +Small interfering rna sirna biogenesis 0.7382705091841469 1.5288025156824965 0.1263134085541166 1.0 0.4037982419910777 4 Q9UPY3,Q15631 2 +Crmps in sema3a signaling 0.6142465379092121 1.5189498234971253 0.1287751264586325 1.0 0.4097923728079946 7 P49841,Q16555,Q9UIW2,Q00535 4 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.5574978665693974 1.5152792562411894 0.129701699250623 1.0 0.4118028951207281 9 P49427,Q16763,P68036 3 +Cell cycle mitotic 0.3292089893894892 1.5067825500879026 0.131866403808367 1.0 0.4177264537875027 264 Q9Y248,Q15691,P00374,P30153,O43768,P49721,P04183,O00716,P28070,Q13200,Q14203,Q96CS2,Q92973,P20618,Q9BVA1,Q9HC35,Q14738,P07437,P33991,P39748,Q07864,P49642,P41208,P35244,Q9BPX3,O75832,P18858,O60763,Q9BRT9,Q9UPP1,P28072,O95067,P43034,Q6P1K2,Q13309,P49720,Q7Z460,P15927,P28074,P24941,P62826,P49643,Q01105,P30154,Q7L590,P60900,Q14674,Q9P258,P25788,P08238,P53990,P31350,P31751,Q99436,P61163,P61289,P28066,O43237,Q13409,O75122,O14965,O94927,P04350,Q9UN37,P51665,P42771,Q9Y266,Q15008,Q99460,Q99640,P48556,P62333,Q92674,Q16763,P63208,O00232,P17612,P17980,P62195,P25789,Q99986,P63151,P25205,P19784,P25786,P07900,O43242,P06493,O75330,P62191,O14980,Q9H6D7,P49736,Q9UNM6,P61981,P40938,P40937,Q00534,Q9HBM1,Q9UBD5,Q9Y6G9,O75935,P25787,P49841,O43913,O00231,Q15003,P23258,Q9BUF5,Q9UL46,P62258,P56282,P35251,P42695 114 +Glycogen storage diseases 0.7312415849432965 1.499128459462167 0.1338403098124339 1.0 0.4230201647239143 4 P46976 1 +Nicotinamide salvaging 0.8600018645730456 1.4898989993666942 0.1362507947211377 1.0 0.4296667273711726 3 Q9BQG2 1 +Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.8454572012854304 1.486180869659568 0.1372312862219469 1.0 0.4301095312751887 2 Q6SZW1 1 +Regulation of localization of foxo transcription factors 0.644925416788545 1.4825992950778974 0.1381809045483892 1.0 0.4308900081564727 6 P31751,P61981,P27348,P63104,P31946 5 +Budding and maturation of hiv virion 0.5201630077839214 1.4798989418669923 0.1389002181289638 1.0 0.4315468270105065 12 Q9NZZ3,Q9UN37,Q96PU5 3 +Purine salvage 0.6414156186019405 1.4663748526219855 0.1425461933844483 1.0 0.4386278241367274 6 P00491,P55263,P07741,Q01433,Q9P2T1 5 +Generation of second messenger molecules 0.7225141103041101 1.462237048401661 0.1436762624726211 1.0 0.4394736855390027 4 Q16512,Q13177 2 +Mitotic prometaphase 0.3193311554121661 1.461913792684462 0.1437648348542048 1.0 0.4394736855390027 93 Q15691,O14980,P30153,Q9H6D7,P61981,Q9Y266,P07900,Q14203,Q96CS2,P30154,Q9BVA1,Q92674,Q9HC35,Q9HBM1,Q14738,Q9P258,Q9Y6G9,P07437,P17612,O75935,P41208,P61163,Q9BPX3,P23258,Q15003,Q9BUF5,P62258,O43237,O95067,P43034,Q6P1K2,Q13409,P19784,O75122,Q7Z460,O94927,P04350,P06493 38 +Chaperone mediated autophagy 0.6394379013524982 1.4572274889233134 0.145053594982141 1.0 0.4405214612827195 6 P08238,O60664,Q99497,P07900 4 +Constitutive signaling by akt1 e17k in cancer 0.5633270180709626 1.4511927126023374 0.1467262055506049 1.0 0.4441430160692097 8 Q9Y243,P31751,P42345,P49841,Q96B36 5 +Regulation of cholesterol biosynthesis by srebp srebf 0.422277035541629 1.449853470129389 0.1470993850460642 1.0 0.4441430160692097 25 Q16850,P14324,Q9UBM7,O95487,O95486,Q13907,Q15436,Q86X55 8 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4389968193466049 1.4449740559762088 0.1484651731055133 1.0 0.445076924524468 22 Q07864,P56282,P35251,P12004,P35244,P27695,Q86W56,P40938,P40937,P15927,P28340,P18858,P39748 13 +Translesion synthesis by polh 0.5013868882261238 1.4407697662949617 0.1496497375207459 1.0 0.4453512619097091 13 P35251,P12004,P35244,P40938,P40937,P15927 6 +Regulation of runx1 expression and activity 0.8457042665108112 1.4341646356718083 0.1515252863451603 1.0 0.4478505792491419 3 Q9HCE1,Q00534 2 +Signaling by vegf 0.3670706593645263 1.432096245023698 0.1521162789621277 1.0 0.4481367770314198 34 Q16539,P04792,O43865,Q9UQB8,P46108 5 +Processing of dna double strand break ends 0.3993166984333012 1.4279296344447971 0.1533121128950334 1.0 0.4494804228912669 28 Q9UQ84,P35244,O60921,O96028 4 +Toll like receptor 9 tlr9 cascade 0.4314224708886786 1.4271534354129378 0.1535356729830459 1.0 0.4494804228912669 23 P09429,Q16539,Q8IV63,Q15075,Q02750,P30154,Q99570,P30153,Q8NEB9,Q14738,P51452 11 +Semaphorin interactions 0.4306874597002164 1.4218878810625295 0.1550588018942926 1.0 0.4503474973936109 23 P08238,P60660,P49841,O75116,Q13177,Q13464,P23528,P07900,Q9UIW2,Q14195,Q9BPU6,Q16555,Q16512,P35579,Q00535 15 +Activation of bh3 only proteins 0.5275932769719905 1.407845558674253 0.1591768066283783 1.0 0.4603933723806304 10 P31751,P61981,Q04917,P27348,P63104,P31946 6 +Bmal1 clock npas2 activates circadian gene expression 0.8385456672662872 1.4062482188776717 0.1596504303524177 1.0 0.460809196699024 3 P43490 1 +Mastl facilitates mitotic progression 0.6747933877421265 1.4032122362364403 0.1605535598360701 1.0 0.4624604599814226 5 O43768,P30154,P30153 3 +Nuclear receptor transcription pathway 0.7079801227711406 1.4007088209721816 0.1613011638329715 1.0 0.4636578721700849 4 Q9UHY1,Q15648,P04150 3 +Pp2a mediated dephosphorylation of key metabolic factors 0.8366452367036747 1.3988366588203502 0.1618619704857351 1.0 0.4643145231387515 3 P30154,P30153 2 +Mitochondrial biogenesis 0.3624400810147282 1.3905629353379598 0.1643580023803106 1.0 0.4686810256264663 34 P48735,Q16539 2 +Attenuation phase 0.4928107459103039 1.3904554297653156 0.1643906245933919 1.0 0.4686810256264663 13 P08238,P25685,Q92598,P04792,Q02790,O75190,P07900 7 +Carboxyterminal post translational modifications of tubulin 0.6243756639515956 1.3874545893120505 0.1653031890006306 1.0 0.4698511661750579 6 Q9BUF5,Q9BVA1 2 +Raf independent mapk1 3 activation 0.6234354676393872 1.383093850110691 0.1666360911446798 1.0 0.4704144763488701 6 P36507,Q06124,Q02750,P06493 4 +Sema3a pak dependent axon repulsion 0.5497903487442581 1.380802260294048 0.1673397683469701 1.0 0.4704144763488701 8 P08238,Q13177,Q9UIW2,Q16512,P07900 5 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.5115998869616165 1.3742247336740343 0.1693719244094844 1.0 0.4704144763488701 11 Q9C005,Q9UBL3 2 +Tnfr1 induced nfkappab signaling pathway 0.584459585414781 1.373126957318102 0.169712881946908 1.0 0.4704144763488701 7 Q13107,Q13546,O15111,P98170 4 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6663303529980867 1.3661279547826808 0.1718988054494303 1.0 0.471049658306784 5 Q14738,P30154,P30153 3 +Activation of gene expression by srebf srebp 0.4488350727710918 1.364654312792387 0.1723617255228515 1.0 0.471049658306784 17 Q86X55,Q9UBM7,Q16850 3 +Folding of actin by cct tric 0.546551328193488 1.363931884570491 0.1725890046517295 1.0 0.471049658306784 8 P17987,P50991,P78371,P40227,P48643,P49368 6 +Diseases of carbohydrate metabolism 0.5195544118548484 1.3637713779128935 0.1726395311761441 1.0 0.471049658306784 10 P46976,P37837,P15586 3 +Uptake and function of anthrax toxins 0.6989614474654209 1.36248731648599 0.1730441442434585 1.0 0.4712332738949542 4 Q02750 1 +Intraflagellar transport 0.4976769531358274 1.35169218540673 0.1764738060055277 1.0 0.4764223306097011 12 Q92973,Q9BVA1,Q9BUF5,A0AVF1,P04350 5 +Organelle biogenesis and maintenance 0.3068227587094123 1.3514947326678448 0.1765370060792954 1.0 0.4764223306097011 101 P48735,Q15691,P30153,Q9H6D7,P61981,P07900,Q14203,Q96CS2,Q92973,Q16539,Q9UPT5,Q9BVA1,Q9Y496,P78371,Q15648,P07437,P17612,A0AVF1,Q15019,O43924,O75935,P41208,P36405,P61163,Q04837,P23258,Q9BUF5,Q00059,A6NIH7,Q13409,P43034,Q86X55,Q15051,Q7Z460,O94927,P04350,P06493 37 +Protein ubiquitination 0.4090502004741951 1.3511268296911332 0.1766548083434682 1.0 0.4764223306097011 25 P49427,Q92541,O95999,Q14527,O75150,Q16763,P12004,Q93008,Q9GZS3,P68036,P78527 11 +Biological oxidations 0.3347577095497778 1.3435433251158435 0.179096106998656 1.0 0.4799941096254619 46 Q8WUX2,Q16850,Q9UI30,P28161,Q6QHF9,P21266,Q9HBK9,Q9NZL9 8 +Rho gtpases activate formins 0.3207833403641159 1.3389829517462883 0.1805762229584449 1.0 0.4799941096254619 59 Q15691,P30153,Q9Y266,P35080,P30154,Q9BVA1,Q92674,Q9HBM1,Q14738,P07737,Q9P258,Q9Y6G9,Q9BUF5,O43237,Q13409,P43034,Q6P1K2,O75122,O60879,Q7Z460 20 +G2 m dna damage checkpoint 0.3548854274864009 1.3355700941558917 0.1816898304344385 1.0 0.4816331937702289 35 Q9UQ84,P35244,O60921,O96028 4 +Dna repair 0.2883445515102843 1.3321155978722574 0.182822205572553 1.0 0.481891738084635 119 Q9NVI1,Q99504,Q9UQ84,P61201,Q9H1I8,P15927,P24941,P53041,Q9NYB0,Q8N3C0,Q15004,Q9NY27,Q13535,Q9ULR0,O96028,Q9UNS1,O60921,P39748,Q07864,P41208,P35244,Q7L5N1,Q9NZJ0,Q9UBW8,P18858,P55199,Q9UNS2,P54727,P13051,P54725,Q92905,Q04323 32 +G2 phase 0.8068945369558883 1.3247302787951765 0.1852606267095171 1.0 0.4828527901365587 2 O00716 1 +Phospholipid metabolism 0.3266894674715257 1.3135640337949206 0.1889929588269707 1.0 0.4862305036487627 52 Q13614,P42356,Q8NEB9,Q8N2A8,Q9NPH0,Q9HBU6,Q01968,Q8NCE2,P35790 9 +Signaling by receptor tyrosine kinases 0.2712758786015626 1.310009633568436 0.1901925766372483 1.0 0.48841733375411 130 Q93034,Q9UBC2,Q8IV63,P30153,Q99570,P36507,Q06124,P61201,Q13043,Q96J02,O43251,P46108,P16949,Q16512,P31946,Q16539,Q02750,Q96JJ3,P30154,Q16543,Q14738,Q9UQB8,P52597,P46109,P31751,Q8NEB9,P40818,P04792,Q92783,O43865,P46934,Q00535,Q8WX92,P51452 34 +Activation of ampk downstream of nmdars 0.5358600955555953 1.3081898535897385 0.1908089226768796 1.0 0.4891010366598181 8 P54619,Q9BVA1,Q13131,Q9BUF5,P04350 5 +Met activates rap1 and rac1 0.6504798965965789 1.2966107652964611 0.1947651465057156 1.0 0.4936670923149645 5 P46108 1 +Dna replication initiation 0.6045255967913526 1.2952944051823554 0.1952186884984286 1.0 0.4936670923149645 6 Q07864,P49643,P49642 3 +Recognition of dna damage by pcna containing replication complex 0.426212526108162 1.2927314770545717 0.196103947066643 1.0 0.4936670923149645 20 Q07864,P56282,P35251,P12004,P35244,P40938,P40937,P15927,Q9NZJ0,P28340,P27694 11 +Metabolism of water soluble vitamins and cofactors 0.3409639982340249 1.2823754313149096 0.1997109785009769 1.0 0.4953667726190127 40 P00374,P43490,Q9BQG2 3 +Signaling by csf3 g csf 0.5657623637514843 1.281237004837118 0.2001104320145881 1.0 0.4953667726190127 7 Q93034,Q06124,Q15370 3 +Dscam interactions 0.8060454012343287 1.2795604113960035 0.2006997804598147 1.0 0.4953667726190127 3 Q16539 1 +Condensation of prometaphase chromosomes 0.501874287657726 1.2666610352819616 0.2052765181125582 1.0 0.4979301574498959 10 O95067,P19784,P06493,Q9BPX3 4 +Trna modification in the nucleus and cytosol 0.4327080484979532 1.259240092242995 0.2079436243881878 1.0 0.5032895103110374 17 Q9UI30,Q7Z4G4,Q9NXH9,Q9NX74,Q9UBP6,Q9UJA5 6 +Tnfr1 induced proapoptotic signaling 0.7902424773590426 1.2552022090087598 0.2094053638426749 1.0 0.5035099712361737 2 Q13546 1 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5238941755441326 1.2457340006879865 0.2128620667099596 1.0 0.5069787295090793 8 P49841,Q14738,P30154,P30153 4 +Beta catenin phosphorylation cascade 0.5238941755441326 1.2457340006879865 0.2128620667099596 1.0 0.5069787295090793 8 P49841,Q14738,P30154,P30153 4 +Signaling by ctnnb1 phospho site mutants 0.5238941755441326 1.2457340006879865 0.2128620667099596 1.0 0.5069787295090793 8 P49841,Q14738,P30154,P30153 4 +Metabolism of nitric oxide nos3 activation and regulation 0.6374269005847863 1.2393477421464458 0.2152167453091311 1.0 0.5069787295090793 5 Q9Y314,P07900,P35270,P50570 4 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3939889494413886 1.2385892594615229 0.2154976476753176 1.0 0.5069787295090793 25 P52597,P37837,Q13126,Q13177,O00170,Q53EL6,P05388,Q99439,P14174,Q9UL46,Q00169,P11233 12 +Transport of connexons to the plasma membrane 0.6371882396027202 1.2383009465764905 0.215604492955604 1.0 0.5069787295090793 5 Q9BUF5,Q9BVA1 2 +Gap junction assembly 0.6371882396027202 1.2383009465764905 0.215604492955604 1.0 0.5069787295090793 5 Q9BUF5,Q9BVA1 2 +Dna damage reversal 0.6369889450877746 1.2374268270523745 0.2159286643220488 1.0 0.5069787295090793 5 Q9H1I8 1 +Mrna decay by 3 to 5 exoribonuclease 0.4552779319916468 1.2351350289362066 0.2167802545759816 1.0 0.5081241873198763 14 Q96C86,Q969T7,Q9Y2L1,Q9GZS3,Q15477 5 +Mtorc1 mediated signalling 0.46584333727592 1.2318621675408064 0.2180005758103382 1.0 0.5101286505980612 13 P23588,P62942,P42345,P62753,Q04637,Q96B36,P31946 7 +Endosomal sorting complex required for transport escrt 0.4639608409863051 1.220785293219446 0.2221673235710082 1.0 0.5152318253363162 13 Q9H9H4,Q9UN37,O14964,Q99816,O75351,Q9NZZ3,Q92783,Q9NP79 8 +Bbsome mediated cargo targeting to cilium 0.553351305323899 1.2201862798696266 0.2223942667700778 1.0 0.5152318253363162 7 Q9NQ48,P17987,P50991,P78371,P49368 5 +Synthesis of ip3 and ip4 in the cytosol 0.6642801251401315 1.215454231986336 0.2241928946320648 1.0 0.517681774877677 4 Q01968 1 +Akt phosphorylates targets in the cytosol 0.5503174722770109 1.2052639022776253 0.2281014401960495 1.0 0.5227609581499447 7 P49841,Q96B36,Q9Y243,P31751 4 +Hdr through homologous recombination hrr 0.3771118104932613 1.2009025823734212 0.2297889924352256 1.0 0.5228260951661404 27 Q9UQ84,P35244,O60921 3 +G2 m dna replication checkpoint 0.6558853675364844 1.1799131388222452 0.2380347636504087 1.0 0.5346214868482654 4 O95067,Q99640 2 +Purine ribonucleoside monophosphate biosynthesis 0.4847475573490973 1.1725206014564176 0.2409881058706748 1.0 0.5395198459957257 10 P22102,Q06203,P30520,P22234,P31939,P49915 6 +Mtor signalling 0.4117378695097088 1.1678381055362017 0.2428720742818719 1.0 0.5420004596993213 19 P23588,P06730,P62942,P31751,P42345,P62753,Q04637,Q96B36,P31946 9 +Interleukin 17 signaling 0.4181595164217002 1.1641294818649215 0.2443715425832153 1.0 0.5431938251457908 17 Q16539,Q8IV63,Q02750,P30154,P30153,Q14738,P51452 7 +Synthesis of gdp mannose 0.7751712402621229 1.1596369904766783 0.2461966339269934 1.0 0.5444627522651403 3 Q96IJ6 1 +Methionine salvage pathway 0.6504648785237851 1.1569878653601329 0.2472773181147334 1.0 0.5444627522651403 4 Q13126,P17174 2 +Synthesis of pips at the late endosome membrane 0.6501421263650171 1.15562351777225 0.2478351841665675 1.0 0.5444627522651403 4 Q13614,Q8NEB9 2 +Nucleotide biosynthesis 0.4420329875846209 1.1548995153827342 0.2481315779031729 1.0 0.5444627522651403 14 P12268,P11172,P49915,P22102,Q06203,P30520,P22234,P31939,P30566 9 +Extension of telomeres 0.3454007897266632 1.154713045461054 0.2482079555309702 1.0 0.5444627522651403 31 P28340,P35251,P49642,P12004,Q9NYB0,P35244,Q5H9R7,P40938,P40937,P15927,P24941,P49643,P18858,P39748 14 +Synthesis of ip2 ip and ins in the cytosol 0.7657026000584382 1.153212122157431 0.248823329147279 1.0 0.5444627522651403 2 Q01968 1 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6166666666666767 1.1483754481583774 0.2508136046838327 1.0 0.5448601910650002 5 O00716,Q00534,P11802,P24941 4 +Lagging strand synthesis 0.4086713346846882 1.1472301465014578 0.2512865152870276 1.0 0.5448601910650002 19 P28340,P35251,P49642,P12004,P35244,P40938,P40937,P15927,P49643,P18858,P39748 11 +Met receptor recycling 0.6162515608943182 1.146558976759988 0.2515639393249285 1.0 0.5448601910650002 5 P46108 1 +Met promotes cell motility 0.504699809110984 1.1455463793488088 0.2519828946507276 1.0 0.5449227613422082 8 P46108 1 +Termination of translesion dna synthesis 0.4034687149807275 1.1373991856795331 0.2553714475657447 1.0 0.5456015950951746 20 Q07864,P56282,P35251,Q14258,P12004,P35244,Q15004,P40938,P40937,P15927,P28340 11 +Synthesis of pips at the early endosome membrane 0.6127360188260532 1.1311807882986884 0.2579790063178029 1.0 0.5456015950951746 5 Q13614,Q8NEB9 2 +Deactivation of the beta catenin transactivating complex 0.4666319059790551 1.1223254487691026 0.2617240895695918 1.0 0.5456015950951746 11 P98170,P31751,Q9HCK8,Q9UBL3,P63104 5 +Synthesis of pg 0.7654708653288069 1.1221276828243554 0.2618081551025981 1.0 0.5456015950951746 3 Q8N2A8 1 +Telomere extension by telomerase 0.4754605388570382 1.1215247368418864 0.2620645680549951 1.0 0.5456015950951746 10 Q5H9R7 1 +Mapk targets nuclear events mediated by map kinases 0.484182080968121 1.1207697785631463 0.2623858713606699 1.0 0.5456015950951746 9 Q16539,Q8IV63,P30154,P30153,P51452 5 +Erk mapk targets 0.484182080968121 1.1207697785631463 0.2623858713606699 1.0 0.5456015950951746 9 Q16539,Q8IV63,P30154,P30153,P51452 5 +Dna damage bypass 0.3663834184482665 1.1174332415174293 0.2638091286721473 1.0 0.5456015950951746 27 Q07864,P56282,P35251,Q14258,P12004,P35244,Q15004,P40938,P40937,P15927,Q9NZJ0,P28340,P27694 13 +Inactivation of csf3 g csf signaling 0.6089375048253586 1.1145770059318776 0.2650317284314245 1.0 0.5456015950951746 5 Q93034,Q15370 2 +Synthesis of pips at the er membrane 0.640110980975906 1.1132654520925944 0.2655944394807679 1.0 0.5456015950951746 4 P42356 1 +Nuclear events kinase and transcription factor activation 0.4551900962240082 1.108879955522876 0.2674819719814696 1.0 0.5466386327490672 12 Q16539,Q8IV63,P30154,P30153,Q14738,P51452 6 +Negative feedback regulation of mapk pathway 0.7615824865235142 1.1071228026309774 0.2682408380103309 1.0 0.5470546725553757 3 Q02750 1 +Transcription coupled nucleotide excision repair tc ner 0.3105224454440056 1.104400242216874 0.2694195557780725 1.0 0.548393228741313 47 Q99627,Q13620,P12004,P40938,P40937,P15927,P61201,Q9BT78,Q9ULR0,P18074,Q07864,P35244,Q7L5N1,P28340,P27694,Q9UBW8,P18858,P56282,P35251,P55199,Q9UNS2,P23193,Q92905 23 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4966133158077668 1.1033954570296447 0.2698554686894914 1.0 0.548393228741313 8 P12004,Q86X55,O14965,Q99873,P06493 5 +Ikk complex recruitment mediated by rip1 0.6376503073893475 1.1028902409481 0.2700748327659437 1.0 0.548393228741313 4 Q6SZW1 1 +Synthesis of udp n acetyl glucosamine 0.6368274376835931 1.0994222022529567 0.2715839508928597 1.0 0.5506571544228229 4 Q06210,Q9UJ70 2 +Mapk1 erk2 activation 0.757844521996452 1.0927167134911282 0.2745181991956265 1.0 0.5549955488803041 3 Q06124 1 +Glycogen breakdown glycogenolysis 0.5264152129383368 1.0878604803065803 0.2766567048505599 1.0 0.5577047859685891 7 P46976,P06737,P35573,Q96G03 4 +Cdc6 association with the orc origin complex 0.633038619979787 1.0834643948621767 0.2786023464624165 1.0 0.5587061901397317 4 O00716,Q9UBD5 2 +Smooth muscle contraction 0.4506466164642695 1.0829928567681222 0.2788115936802131 1.0 0.5587061901397317 12 P67936,P04083,P06753,Q16512,O60504 5 +Tgf beta receptor signaling activates smads 0.4592949422711571 1.0813238959238178 0.2795530614943968 1.0 0.5587061901397317 11 Q96PU5 1 +Nucleotide excision repair 0.299331185278528 1.075558543448308 0.2821247364837373 1.0 0.5591787710902615 57 Q99627,Q13620,P12004,P40938,P40937,P15927,P61201,Q9BT78,Q9ULR0,P18074,Q07864,P41208,P35244,Q86WJ1,Q7L5N1,P28340,P27694,Q9UBW8,P18858,P56282,P35251,P55199,Q9UNS2,P54727,P23193,P54725,Q92905 27 +Regulation of tnfr1 signaling 0.5238743485242523 1.075410131234451 0.282191147901671 1.0 0.5591787710902615 7 Q13546,P98170 2 +Vitamin b5 pantothenate metabolism 0.5526141169625943 1.0544515563252868 0.2916762286462002 1.0 0.5739037907306223 6 Q9NRN7,P49327,Q9NVE7 3 +Telomere c strand lagging strand synthesis 0.3791837198859668 1.0529561421841396 0.2923610932921729 1.0 0.5744422606598673 23 P28340,P35251,P49642,P12004,Q9NYB0,P35244,P40938,P40937,P15927,P49643,P18858,P39748 12 +Circadian clock 0.4441435920421014 1.0460076492088346 0.2955575007977424 1.0 0.5790937287720144 12 P43490,P04150 2 +Transcription of the hiv genome 0.3244471795923214 1.0324506580004305 0.3018610510935628 1.0 0.586358559136081 32 P18615,P18074,O60942,P55199,Q08945,O43148,Q9Y5B9,Q14241,Q8IXH7,Q9HBM6,P29083,P23193,P13984,O00267,Q15370,Q8WX92 16 +E3 ubiquitin ligases ubiquitinate target proteins 0.3979268896636733 1.032316287751889 0.3019239733455254 1.0 0.586358559136081 17 Q92541,O95999,Q14527,O75150,P12004,P68036,Q9GZS3,P78527 8 +Synthesis of pips at the golgi membrane 0.4827055405579268 1.03108057319279 0.3025030370507644 1.0 0.586358559136081 8 Q01968,Q8NEB9,P42356 3 +Mhc class ii antigen presentation 0.2989931651094978 1.0309313066708583 0.302573034266719 1.0 0.586358559136081 53 Q9Y6G9,Q9BVA1,P47755,Q9BXS5,Q9UJW0,P61163,P04350,Q13409,Q9BUF5,O95486,O95487,Q14203,Q07866,Q9NZ32,Q15436,O43237 16 +Dual incision in gg ner 0.375025141177998 1.0233963261630494 0.3061204957406394 1.0 0.5914942358916642 23 P18074,Q07864,P56282,P35251,P12004,P35244,Q86WJ1,P40938,P40937,P15927,P28340,P27694 12 +Inositol phosphate metabolism 0.5456831715740722 1.022477887516123 0.3065547731804536 1.0 0.5915152184158754 6 Q01968,Q9NPH2,Q13572 3 +Mapk3 erk1 activation 0.7390414962010612 1.020566839094577 0.3074597071388207 1.0 0.5917236180980626 3 Q06124,Q02750 2 +Cd209 dc sign signaling 0.585631559270449 1.0130832225350794 0.3110204113138848 1.0 0.5941608879301649 5 Q16512,Q13177 2 +Hur elavl1 binds and stabilizes mrna 0.5108111691195497 1.0115490683730548 0.3117537085560564 1.0 0.5941608879301649 7 P39687 1 +Tnf signaling 0.4542865184089644 1.0056724820425735 0.3145731445465922 1.0 0.5979029699749515 10 O95429,Q13546,P98170 3 +Rab regulation of trafficking 0.3113091400901605 1.0022011841215797 0.3162464360279164 1.0 0.5994521996350058 40 P62258,Q9UJY5,P61020,Q7Z392,Q5VZ89,Q9UL25,P50395,P31751,Q8TC07,Q9NVG8,O43617,Q6IQ22,Q8IUR0,Q9Y296,P62330,Q4KMP7,Q15042,P60520 18 +Signaling by wnt in cancer 0.4531712235041407 0.9995944969510332 0.3175067873839245 1.0 0.6002124248651456 10 P49841,Q14738,P30154,P30153 4 +Pkmts methylate histone lysines 0.3917896853044877 0.992546230532834 0.3209311393088585 1.0 0.6034196522402091 17 O96028,Q9UBL3 2 +Interleukin 12 family signaling 0.3322347463756663 0.9891238456856958 0.3226025520705056 1.0 0.6049339130771763 30 P26038,P52597,P37837,Q13126,Q13177,O00170,Q53EL6,P05388,Q99439,P14174,Q9UL46,Q00169,P11233 13 +Toll like receptor tlr1 tlr2 cascade 0.3801679115916542 0.9793064150964594 0.3274286016832783 1.0 0.610279866924238 20 P09429,Q16539,Q8IV63,Q02750,P30154,P30153,Q14738,P51452 8 +Homology directed repair 0.3036250350787057 0.974956132789506 0.3295820202051569 1.0 0.6115654518614264 43 Q9UQ84,P35244,O60921,O96028 4 +Galactose catabolism 0.7266618133037592 0.9734094790263844 0.3303498296520368 1.0 0.6116939496165243 3 Q96G03 1 +Interleukin 12 signaling 0.3475337483611453 0.9718468876038444 0.3311267258442578 1.0 0.6118836455085029 27 P52597,P37837,Q13126,Q13177,O00170,Q53EL6,P05388,Q99439,P14174,Q9UL46,Q00169,P11233 12 +Regulation of tp53 activity 0.2798410332406316 0.9663046086812004 0.3338917806075048 1.0 0.6145544367703348 65 P30153,P42345,Q9UQ84,P42771,P40938,P15927,P24941,Q13526,Q16539,P30154,Q08945,Q9Y5B9,Q13535,O60921,P78356,P31751,Q12873,P35244,Q00535,Q9UER7,P19784,O14965,P06493 23 +Downregulation of erbb2 signaling 0.4697812132515486 0.9641940571738582 0.3349486432927344 1.0 0.6156884929999342 8 Q93034,Q16543,P40818,P31751 4 +Intrinsic pathway for apoptosis 0.3768200504494929 0.9567650206268936 0.3386858713539005 1.0 0.6201103044317156 20 P31751,P98170,P61981,P42771,Q04917,P27348,P63104,P31946 8 +Synthesis of pc 0.5720011365531995 0.9541461528878245 0.3400096668640178 1.0 0.6213756683039872 5 P35790 1 +Cell cycle 0.3093137939343153 0.9536386957234168 0.3402665613833573 1.0 0.6213756683039872 311 Q9Y248,P00374,Q15691,P30153,O43768,Q9UQ84,P49721,P04183,O00716,P28070,Q13200,Q14203,Q96CS2,Q92973,P20618,Q9BVA1,Q9HC35,Q14738,O96028,P07437,O60921,P33991,P39748,Q07864,P49642,P41208,P35244,Q9BPX3,O75832,P18858,O60763,Q9BRT9,Q9UPP1,P28072,O95067,P43034,Q6P1K2,Q13309,P49720,Q7Z460,Q5H9R7,P15927,P28074,P24941,P62826,P49643,Q01105,P30154,Q7L590,Q9NYB0,Q13535,P60900,Q9NWV8,Q14674,Q9P258,P25788,P08238,P53990,Q99436,P31350,P31751,P61163,P61289,P28066,O43237,Q04917,Q13409,O75122,O14965,O94927,P04350,Q9UN37,P51665,P42771,Q9Y266,Q15008,Q99460,Q99640,P48556,P62333,Q92674,Q16763,P63208,O00232,P17612,P17980,P62195,P25789,P63104,Q99986,P63151,Q9UER7,P27348,P25205,P19784,P25786,P07900,O43242,P06493,O75330,P62191,O14980,Q9H6D7,P49736,Q9UNM6,P61981,P40938,P31946,Q00534,Q9HBM1,Q9Y6G9,P25787,P49841,Q9BUF5,Q9UL46,P42695 116 +Peroxisomal protein import 0.3644301912242671 0.9484695594607382 0.3428904624618178 1.0 0.6241747021398049 23 P34913 1 +Costimulation by the cd28 family 0.384804099437888 0.9474577557531808 0.3434055727147576 1.0 0.6241747021398049 17 P30154,P30153,P31751,Q13177,Q14738,Q06124,Q16512 7 +Golgi to er retrograde transport 0.277971970940469 0.947102592350376 0.3435865038980028 1.0 0.6241747021398049 72 P48444,P47755,O15260,Q14203,Q07866,P24390,Q9BVA1,Q9Y496,Q9Y678,Q9Y6G9,Q8TD16,P35606,P53621,P61923,P61163,Q9BUF5,Q9NZ32,Q15042,O43237,Q9UBF2,Q9UJW0,Q13409,Q8N6T3,P43034,A2RRP1,Q15102,P04350 27 +Gap filling dna repair synthesis and ligation in gg ner 0.3778217872382325 0.941274469996898 0.3465642223429357 1.0 0.6271375888770482 19 Q07864,P56282,P35251,P12004,P35244,P40938,P40937,P15927,P28340,P18858 10 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.5676460070860707 0.9354010811075528 0.3495816399719675 1.0 0.6313282094132655 5 O14980,P31751 2 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3618148274241706 0.93007547366653 0.3523320085338395 1.0 0.6351068592539016 23 Q07864,P56282,P35251,Q14258,P12004,P35244,Q15004,P40938,P40937,P15927,P28340 11 +Pd 1 signaling 0.7104878761320572 0.9276047420208108 0.3536126370159689 1.0 0.636033942419631 2 Q06124 1 +Formation of rna pol ii elongation complex 0.3243747447679723 0.9245720416899084 0.3551885616338417 1.0 0.6369608550193236 30 P18074,P55199,Q08945,Q92541,Q9Y5B9,Q14241,Q8IXH7,Q9GZS3,P23193,P13984,Q15370,Q8WX92 12 +Potential therapeutics for sars 0.30383584235334 0.91976703011544 0.3576945159542535 1.0 0.6398197679745098 39 P62942,P04150,Q99720 3 +Er to golgi anterograde transport 0.2771989387402666 0.9040351737660258 0.365976750659601 1.0 0.6488191886693687 82 P48444,P47755,O43617,Q5H9R7,Q12955,Q9UP83,Q14203,P24390,P83436,Q9BVA1,Q9Y678,Q9Y296,O95486,O95487,Q9Y6G9,Q9Y6Y8,P35606,P53621,P61923,P61163,Q92734,Q8IUR0,Q9BUF5,Q9NZ32,O43237,O60763,Q9UJW0,Q13409,Q8N6T3,Q15436,P04350 31 +Synthesis of leukotrienes lt and eoxins ex 0.706935332923932 0.8989816370824376 0.3686624417309472 1.0 0.6494595600228665 3 Q14914 1 +Map3k8 tpl2 dependent mapk1 3 activation 0.5581871345029126 0.894858138699047 0.3708629267327255 1.0 0.6508737545799215 5 O15111,Q02750,Q13616,P63208 4 +Uptake and function of diphtheria toxin 0.5862738841867194 0.8885678820371281 0.3742353587058402 1.0 0.6544174038178243 4 P08238,P07900 2 +Signaling by alk in cancer 0.3069156935218267 0.8880845109047358 0.3744952937262482 1.0 0.6544174038178243 33 O43815,P26038,P49589,P06753,P26641,Q9HC35,P67936,Q8IWJ2,P63208,Q92734,P62753,Q14203,Q07866 13 +Copi mediated anterograde transport 0.2815932586643975 0.8845506723818995 0.3763990211751484 1.0 0.6554174626949917 57 P48444,P47755,Q9UP83,Q12955,Q14203,P83436,P24390,Q9BVA1,Q9Y678,Q9Y6G9,O75935,P35606,P53621,P61923,P61163,Q9BUF5,Q9NZ32,P84085,O43237,O60763,Q9UBF2,Q9UJW0,Q13409,Q8N6T3,P04350 25 +Cargo recognition for clathrin mediated endocytosis 0.3011845623435626 0.8839262574126552 0.3767360218640503 1.0 0.6554174626949917 38 Q9UBC2,Q9UNS2,Q7L5N1,Q9UBW8,Q92905,P20645 6 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.405559800701427 0.8800057817527506 0.3788561774243644 1.0 0.6574684221886175 13 Q16539,P51617,Q96J02 3 +Negative regulation of the pi3k akt network 0.3852259304931362 0.8712983924731872 0.3835912479892847 1.0 0.6632140760408796 15 O43815,P30154,P78356,P30153,Q14738,Q06124,P51617 7 +Apoptotic factor mediated response 0.4493741617639688 0.8595434399697673 0.3900407644604038 1.0 0.6670635398903249 8 P98170 1 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.3735052215468448 0.8588383597758171 0.3904297008033235 1.0 0.6670635398903249 16 P09429,P08238,Q9UII4,Q96J02,Q13526,Q13546 6 +Foxo mediated transcription 0.4108258112326223 0.8585430289684902 0.3905926811956233 1.0 0.6670635398903249 12 P31751,P27348,P04150,P63104,P31946 5 +Deadenylation dependent mrna decay 0.2960763751553116 0.849042519817576 0.3958576328823153 1.0 0.6746535542569492 39 Q96C86,Q969T7,Q5TAX3,Q9GZS3 4 +Signaling by tgf beta receptor complex 0.3618463256093995 0.8363975725855918 0.4029312777383942 1.0 0.6831249939326902 19 P62942,O14980,Q93008,Q9Y3F4,Q96PU5 5 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.5437719086089533 0.8335923455385982 0.4045107404552981 1.0 0.6849715205043049 5 P46108 1 +Nef mediated downregulation of mhc class i complex cell surface expression 0.5716286826506687 0.8286834084674186 0.4072835766337412 1.0 0.6866546556321791 4 Q9BXS5,P04439 2 +Assembly and cell surface presentation of nmda receptors 0.4053320905822283 0.8281084225406101 0.407609100021872 1.0 0.6866546556321791 12 Q9BUF5,P07196,Q9BVA1 3 +Unwinding of dna 0.413291576394831 0.8274750223168497 0.4079678736264369 1.0 0.6866546556321791 11 Q9Y248,Q9BRT9,P49736,P25205,P33991 5 +Processive synthesis on the lagging strand 0.3961073705959693 0.8260088069403705 0.4087990959598779 1.0 0.6866546556321791 13 P28340,P49642,P35244,P12004,P15927,P49643,P18858,P39748 8 +Polb dependent long patch base excision repair 0.5024997566633012 0.8257509845659446 0.4089453639842326 1.0 0.6866546556321791 6 P27695,P18858,P39748 3 +Base excision repair 0.3117384122913034 0.8221160815373144 0.4110108337099358 1.0 0.6876432750811741 30 Q07864,P56282,P35251,P12004,Q9NYB0,P27695,P35244,Q86W56,P40938,P40937,P15927,P13051,P28340,P18858,P39748 15 +Resolution of sister chromatid cohesion 0.2713158311756165 0.816815682688996 0.414033768574658 1.0 0.6910456089591365 61 Q15691,P30154,P30153,Q9BVA1,Q92674,Q9HBM1,O95067,Q14738,Q9Y266,Q9BUF5,Q9P258,P43034,Q6P1K2,Q9Y6G9,O75122,Q13409,Q7Z460,O43237 18 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.4172767203513969 0.8062628627999239 0.4200912988995866 1.0 0.6944065022229235 10 Q10567,P04439,Q96CW1,P53680,P63010,O43747,O94973,Q9BXS5,O95782 9 +Stimuli sensing channels 0.416722976960964 0.8033263016901091 0.4217861596209227 1.0 0.6944065022229235 10 Q9H4A3,Q13546,Q96PU5 3 +Protein folding 0.2897163624365439 0.8030104427788125 0.4219686987506392 1.0 0.6944065022229235 40 Q9NQP4,O15212,Q9BVA1,Q99426,Q9UHV9,Q15813,Q15814,P78371,Q99471,P61758,Q9BUF5,Q15477,P04350 13 +Gap junction trafficking and regulation 0.400346307449275 0.8006452324592166 0.4233370568747701 1.0 0.6944065022229235 12 Q9BVA1,P50570,P09497,Q9BUF5,P04350 5 +Sulfur amino acid metabolism 0.4066585382141282 0.7916372162831824 0.428572240142796 1.0 0.6994339012610818 11 Q96SZ5,Q13126,P17174 3 +Pi5p regulates tp53 acetylation 0.5622501464306873 0.7907369990562038 0.4290974806215915 1.0 0.6994739561591171 4 Q13526 1 +Runx3 regulates p14 arf 0.6742623429740187 0.7845888668579714 0.4326946596304171 1.0 0.7012538669793152 2 P42771 1 +Formation of tc ner pre incision complex 0.3275914778522413 0.7845810632599952 0.4326992364611093 1.0 0.7012538669793152 26 Q9UBW8,Q92905,Q9ULR0,Q9UNS2 4 +Notch4 activation and transmission of signal to the nucleus 0.6733859187846949 0.7811976881026846 0.4346862332628196 1.0 0.7033915351056106 2 P63104 1 +Rho gtpase effectors 0.2524719960788591 0.7760625873530393 0.4377120323947336 1.0 0.7036805124967875 118 O15144,Q15691,O14980,P30153,Q99570,P61981,Q9Y266,P35080,Q13526,Q07866,P60660,Q16512,P31946,Q16539,Q9HD26,P30154,Q9BVA1,Q92674,Q9HBM1,Q14738,P07737,Q9P258,Q9Y6G9,Q9UQB8,Q14204,O15145,O60566,Q8NEB9,O75116,Q13177,P23528,Q9BUF5,P63104,P62258,O43237,P46940,Q04917,Q13409,P43034,Q6P1K2,P27348,Q9NZQ3,O75122,O60879,Q7Z460,P04350 46 +Formyl peptide receptors bind formyl peptides and many other ligands 0.6733770147103981 0.7750093149846189 0.4383341553567379 1.0 0.7036805124967875 3 P04083 1 +Transport to the golgi and subsequent modification 0.2667701510108543 0.7740919434271819 0.4388764214744112 1.0 0.7036805124967875 85 P48444,P47755,O43617,Q5H9R7,Q12955,Q9UP83,Q14203,P24390,P83436,Q9BVA1,Q9Y678,Q9Y296,O95486,O95487,Q9Y6G9,Q9Y6Y8,P35606,P53621,P61923,P61163,Q92734,Q8IUR0,Q9BUF5,Q9NZ32,Q16706,O43237,O60763,Q9UJW0,Q13409,Q8N6T3,Q15436,P04350 32 +Phenylalanine and tyrosine metabolism 0.5287197648457479 0.770437011683295 0.4410407055578269 1.0 0.7049586563664579 5 P16930 1 +Polymerase switching on the c strand of the telomere 0.3582804756680414 0.7641222902522038 0.4447943701042174 1.0 0.7087855354281004 16 P35251,P49642,P12004,Q9NYB0,P40938,P40937,P49643 7 +Sema4d induced cell migration and growth cone collapse 0.4587009170366762 0.7613963821183469 0.4464203477257511 1.0 0.710218498262079 7 Q13464,O75116,P60660,P35579 4 +Resolution of abasic sites ap sites 0.3192667132761055 0.7587128225416511 0.4480243647690358 1.0 0.710218498262079 27 Q07864,P56282,P35251,P12004,P35244,P27695,Q86W56,P40938,P40937,P15927,P13051,P28340,P18858,P39748 14 +Negative regulation of fgfr3 signaling 0.5241014286418785 0.7512552965840827 0.4524990271530327 1.0 0.710218498262079 5 P30153 1 +Spry regulation of fgf signaling 0.5241014286418785 0.7512552965840827 0.4524990271530327 1.0 0.710218498262079 5 P30153 1 +Negative regulation of fgfr2 signaling 0.5241014286418785 0.7512552965840827 0.4524990271530327 1.0 0.710218498262079 5 P30153 1 +Negative regulation of fgfr1 signaling 0.5241014286418785 0.7512552965840827 0.4524990271530327 1.0 0.710218498262079 5 P30153 1 +Negative regulation of fgfr4 signaling 0.5241014286418785 0.7512552965840827 0.4524990271530327 1.0 0.710218498262079 5 P30153 1 +Translation of replicase and assembly of the replication transcription complex 0.5239217798837281 0.7505111706082928 0.4529468985652176 1.0 0.710218498262079 5 Q8NEB9 1 +Signaling by moderate kinase activity braf mutants 0.3558017503889428 0.7488857205817833 0.4539260876016997 1.0 0.7109133905600611 16 P41240,Q7Z569,Q02750,P36507,P30086,P10398,P31946,P46940 8 +Signaling by met 0.3418947689197688 0.7461440378839194 0.4555804093697966 1.0 0.7119632521825988 21 Q92783,P46108,P40818,P46109 4 +Wnt ligand biogenesis and trafficking 0.5219066815005147 0.7421750890719978 0.45798125951851 1.0 0.7140622986019626 5 O75436 1 +Condensation of prophase chromosomes 0.3958105906238632 0.7336515524889665 0.4631611327365013 1.0 0.721333447528308 11 Q9UPP1,Q01105 2 +Signaling by fgfr1 0.4807918248329493 0.7293953475635773 0.4657598628768014 1.0 0.7229628093765461 6 P30153 1 +Signaling by fgfr4 0.4807918248329493 0.7293953475635773 0.4657598628768014 1.0 0.7229628093765461 6 P30153 1 +Signaling by fgfr3 0.4807918248329493 0.7293953475635773 0.4657598628768014 1.0 0.7229628093765461 6 P30153 1 +Josephin domain dubs 0.6595629016364856 0.7252070891878372 0.4683249944101393 1.0 0.7255976499413269 3 P54725 1 +Rna polymerase iii transcription termination 0.4792405890395537 0.7226002139565523 0.4699255367574726 1.0 0.7255976499413269 6 Q9NVU0 1 +Innate immune system 0.2927607557440686 0.7223906862331629 0.4700543115224773 1.0 0.7255976499413269 294 O75874,P30153,P49721,O15260,Q06124,P28070,Q13200,P81605,Q15075,Q16539,P19474,P20618,Q14738,P07437,P14174,Q9UQB8,P30740,Q13442,O43865,O75832,Q9NZ32,Q99439,Q13546,P00491,P18669,P28072,Q86VP6,P49720,Q9NVU0,Q99570,P15586,P28074,Q13526,P46108,P51617,Q6SZW1,Q96JJ3,Q96G03,P30154,P60900,Q9BRF8,P46976,P25788,P08238,P53990,Q99436,P36871,P42785,Q13177,P61289,Q7Z6Z7,P28066,P49427,Q9UII4,P51452,P17931,P51665,P47755,Q15008,Q96J02,Q99460,Q16512,P48556,P09429,P62333,P78371,P63208,O00232,P07741,P13010,P14618,P17612,P17980,O95721,P04080,P06744,P62195,P25789,Q8NEB9,P22392,Q8IV08,P25786,O43242,Q8IV63,Q9UNM6,Q5T4S7,Q02750,Q9Y6G9,P06737,P25787,Q9UL46,P30041,O95999,Q9BXS5 94 +Flt3 signaling 0.4780113633129107 0.717225205706327 0.4732351489545237 1.0 0.7283261601778794 6 P41240,Q06124,Q9Y243,P31751 4 +Tbc rabgaps 0.3503819228506964 0.7157798712804019 0.4741272832454022 1.0 0.7283261601778794 16 Q9UJY5,Q8TC07 2 +Nuclear signaling by erbb4 0.543390896132375 0.7155741733181882 0.474254325626013 1.0 0.7283261601778794 4 P16949 1 +Signaling by tgfb family members 0.3389768376547959 0.7076423142425088 0.4791674086457484 1.0 0.7342839339042455 20 Q96PU5 1 +Caspase activation via death receptors in the presence of ligand 0.6538124452234996 0.706485365403536 0.4798863505043493 1.0 0.7342839339042455 2 Q13546 1 +Regulation by c flip 0.6538124452234996 0.706485365403536 0.4798863505043493 1.0 0.7342839339042455 2 Q13546 1 +Base excision repair ap site formation 0.5114299145647305 0.6991682671718543 0.4844468793173873 1.0 0.7379369156846268 5 Q9NYB0 1 +Role of abl in robo slit signaling 0.5390244145022689 0.698419506455607 0.4849148808865335 1.0 0.7379369156846268 4 O75122,Q7Z460 2 +Peptide ligand binding receptors 0.4444938081083728 0.6953059183386019 0.4868636060883511 1.0 0.7384890963142524 7 Q9BYT8,P04083 2 +Class a 1 rhodopsin like receptors 0.4444938081083728 0.6953059183386019 0.4868636060883511 1.0 0.7384890963142524 7 Q9BYT8,P04083 2 +Rap1 signalling 0.5080692651982307 0.6854993077369826 0.4930288973241157 1.0 0.743726062050435 5 P17612,P31946 2 +Formation of fibrin clot clotting cascade 0.6479608372173906 0.6840503374771385 0.493943380197273 1.0 0.743726062050435 3 P42785 1 +Signaling by hippo 0.4405534251545181 0.6772029044070331 0.4982772252370728 1.0 0.7468812056396896 7 P62258,Q13043,P31946 3 +Downregulation of erbb2 erbb3 signaling 0.6443600233781466 0.6714129292527624 0.5019575106341783 1.0 0.7492699162113539 3 P40818,P31751 2 +Runx2 regulates genes involved in cell migration 0.6441717791411135 0.6704789052708523 0.5025525493844227 1.0 0.7492699162113539 2 P31751 1 +Akt phosphorylates targets in the nucleus 0.6441717791411135 0.6704789052708523 0.5025525493844227 1.0 0.7492699162113539 2 P31751 1 +Aryl hydrocarbon receptor signalling 0.6428988895382882 0.6663042336462636 0.5052166600766708 1.0 0.7521426346870502 3 O00170,P08238 2 +E2f enabled inhibition of pre replication complex formation 0.503190471724694 0.6657730948382904 0.5055561445749035 1.0 0.7521426346870502 5 Q9UBD5,P06493 2 +Ptk6 regulates cell cycle 0.6412503651767565 0.6596814310435114 0.5094582853267444 1.0 0.7555087706757779 2 P24941 1 +Egfr downregulation 0.3944599458775704 0.6496048923499197 0.5159474720805335 1.0 0.7595138234947368 9 Q9UBC2 1 +Enos activation 0.6370543541788527 0.6459844228062591 0.5182894435823999 1.0 0.7605570931561058 3 P07900,P35270 2 +Negative regulators of ddx58 ifih1 signaling 0.4058759916612579 0.6432890506104864 0.5200365597250611 1.0 0.7616800789203935 8 Q13526 1 +Processing and activation of sumo 0.6344449855900995 0.6369734794471047 0.5241421184638886 1.0 0.7645757792304184 3 Q9UBE0 1 +Sumo is transferred from e1 to e2 ube2i ubc9 0.6344449855900995 0.6369734794471047 0.5241421184638886 1.0 0.7645757792304184 3 Q9UBE0 1 +Sumo is conjugated to e1 uba2 sae1 0.6344449855900995 0.6369734794471047 0.5241421184638886 1.0 0.7645757792304184 3 Q9UBE0 1 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.3749780729232123 0.6250104756046083 0.5319641827507997 1.0 0.77411871177382 11 P63241,Q9HA64,Q9BTV6 3 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.6283961437335788 0.6128475293354478 0.5399771603609429 1.0 0.7817078684188987 2 P51617 1 +Pi metabolism 0.3178086187221583 0.61040847706863 0.5415912540786751 1.0 0.7818090354532156 22 Q13614,P42356,P78356,Q99570,Q8NEB9,Q96T51,Q01968,Q8NCE2 8 +Interleukin 20 family signaling 0.6264333298048665 0.6095535728284135 0.5421575742917737 1.0 0.7818090354532156 3 Q06124 1 +Cargo trafficking to the periciliary membrane 0.3145232548789572 0.609360399927451 0.5422855800674058 1.0 0.7818090354532156 23 O75695,A6NIH7,P18085,Q9UPT5,Q9NQ48,P17987,Q8IYI6,P36405,P78371,Q96KP1,Q92538,Q8TAG9,O43924,P49368,Q96A65 15 +Pyrimidine salvage 0.6266432953549677 0.606550547010488 0.5441492276819 1.0 0.7836870835789839 2 P04183 1 +Hiv transcription elongation 0.3138290124474696 0.6048901155855035 0.5452520112257722 1.0 0.783847225116909 23 P18615,P18074,P55199,Q08945,Q9Y5B9,Q14241,Q8IXH7,P23193,P13984,O00267,Q15370,Q8WX92 12 +Sumoylation of dna methylation proteins 0.6224430157802329 0.5960412516626215 0.5511476690796651 1.0 0.7880126085546398 3 P26358,Q9HC52 2 +Retrograde neurotrophin signalling 0.395961369622474 0.5959407373778105 0.5512148175316176 1.0 0.7880126085546398 8 Q00610,P50570,Q96CW1,P53680,P63010,O94973,O95782 7 +Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.3959613696224686 0.5959407373777842 0.5512148175316351 1.0 0.7880126085546398 8 Q00610,Q96CW1,P53680,P09497,P63010,O94973,O95782 7 +Trafficking of myristoylated proteins to the cilium 0.6200893728254286 0.5881179741286261 0.5564531093745952 1.0 0.789917902908002 3 A6NIH7 1 +Hiv elongation arrest and recovery 0.3197829639652391 0.5875197275714301 0.5568547051740784 1.0 0.789917902908002 20 P18615,P55199,Q08945,Q9Y5B9,Q14241,Q8IXH7,P23193,P13984,O00267,Q15370,Q8WX92 11 +Reactions specific to the complex n glycan synthesis pathway 0.6208004674262413 0.585724394499496 0.5580607380981362 1.0 0.789917902908002 2 Q16706 1 +Gdp fucose biosynthesis 0.6187554776511981 0.5784962922569805 0.5629290999257694 1.0 0.789917902908002 2 Q13630 1 +Response of eif2ak1 hri to heme deficiency 0.6168907071887781 0.5774071139591309 0.5636644696247914 1.0 0.789917902908002 3 P20042,P08243 2 +Trans golgi network vesicle budding 0.2621209820252496 0.5708250510948845 0.5681182399453597 1.0 0.789917902908002 41 P15586,Q9H3P7,O00203,P20645,Q14677,Q01968,Q9Y5X3,Q92572,O60749 9 +Metabolism of steroids 0.2555690422787464 0.570699924788745 0.5682030697893179 1.0 0.789917902908002 47 Q15392,Q15125,Q9UBM7,Q16850 4 +Gab1 signalosome 0.614552893044993 0.5696213128740925 0.5689345698315931 1.0 0.789917902908002 3 P41240,Q06124 2 +Prolactin receptor signaling 0.613370587999322 0.565697681595191 0.5715993115369888 1.0 0.789917902908002 3 Q06124 1 +Frs mediated fgfr4 signaling 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Stat5 activation 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Activated ntrk2 signals through frs2 and frs3 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Pi 3k cascade fgfr3 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Pi 3k cascade fgfr4 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Frs mediated fgfr2 signaling 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Signaling by flt3 itd and tkd mutants 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Met activates ptpn11 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Stat5 activation downstream of flt3 itd mutants 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Pi 3k cascade fgfr2 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Frs mediated fgfr1 signaling 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Pi 3k cascade fgfr1 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Frs mediated fgfr3 signaling 0.6143733567046616 0.5631175082317135 0.5733548701136106 1.0 0.789917902908002 2 Q06124 1 +Dna double strand break repair 0.2511292210005432 0.5604738652524794 0.575156261094379 1.0 0.7912202336643279 55 Q07864,Q99504,Q9UQ84,P35244,Q9NY27,Q13535,P15927,Q9UNS1,P24941,O96028,P53041,O60921,Q04323,P39748 14 +Rho gtpases activate pkns 0.317502655360479 0.5587511680436068 0.5763315531624686 1.0 0.7912472944152165 19 P60660,P61981,Q04917,P27348,P62258,Q16512,P63104,P31946 8 +Processive synthesis on the c strand of the telomere 0.3469120310527855 0.5569641153075764 0.57755194712678 1.0 0.7912472944152165 13 P35244,Q9NYB0,P18858,P39748 4 +Synthesis of pips at the plasma membrane 0.3467053723949254 0.5558922312074807 0.5782845294187087 1.0 0.7912472944152165 13 Q13614,P78356,Q96T51,Q01968,Q8NCE2 5 +Rho gtpases activate rocks 0.3560744234771322 0.530435086197248 0.5958103048962518 1.0 0.8070195884151898 11 O75116,Q13464,P23528,P35579,P60660,Q16512 6 +Epha mediated growth cone collapse 0.3697306791569217 0.5290506829495507 0.5967702914575466 1.0 0.8070195884151898 9 Q7Z406,P07948,P61586,O75116,Q13464,P35579,P35580,P60660 8 +Map2k and mapk activation 0.3261129907852708 0.5272575353068623 0.5980147589287428 1.0 0.8070195884151898 15 P41240,Q02750,P36507,P30086,P10398,P31946,P46940 7 +Lysosome vesicle biogenesis 0.325979623104102 0.526532305900871 0.598518411924118 1.0 0.8070195884151898 15 P20645 1 +Regulation of bach1 activity 0.6011654215222378 0.5257604940904 0.5990546264756993 1.0 0.8070195884151898 3 Q13309 1 +Insulin processing 0.354715875805511 0.5238150957176231 0.6004071527976622 1.0 0.8080624204800907 11 Q8TAG9,Q9UPT5,Q8IYI6,Q96HE7,P33176,Q96KP1,O60645,Q9NV70,Q9Y4I1,Q96A65 10 +Ripk1 mediated regulated necrosis 0.3472604927455456 0.5219660691980561 0.6016939554250684 1.0 0.8086955823538913 12 P98170,Q16543,O00560,Q13546,P07900 5 +Signaling by egfr 0.3326328919518276 0.5214757914131449 0.6020353655318875 1.0 0.8086955823538913 14 Q99961,P41240,Q9UBC2,O14964,Q92783,Q06124,Q13685 7 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.4899944282840573 0.5141291422886851 0.607161703777011 1.0 0.8147981750014258 4 Q9HCE1,Q8NB78 2 +Fcgamma receptor fcgr dependent phagocytosis 0.2589260809199745 0.5092594200205118 0.6105703980459787 1.0 0.8185862246355395 36 Q9UQB8,P46108,O43865,Q16512 4 +Signaling by braf and raf1 fusions 0.2863269913516993 0.4995665171862502 0.6173803390595733 1.0 0.8261305878028966 26 P41240,Q02750,P51114,P36507,P18206,P30086,O00203,P10398,Q9NRY5,P31946,P46940 11 +Caspase mediated cleavage of cytoskeletal proteins 0.4252705469435403 0.4967575298137553 0.619360047837604 1.0 0.8269959829898005 6 P08670,P35611,Q13813,P42574,Q9UJU6 5 +Fbxw7 mutants and notch1 in cancer 0.5945077417470159 0.4954088575982763 0.6203115435361577 1.0 0.8269959829898005 2 P63208 1 +Membrane trafficking 0.2715632043421119 0.4952906326468531 0.620394982228569 1.0 0.8269959829898005 267 Q7Z6M1,O75351,O15260,P61201,Q14203,Q9BVA1,Q9Y678,O95486,O95487,Q8IWJ2,Q5VZE5,Q9NZ32,Q9UKS6,Q15042,Q9UBW8,P20645,O60763,Q8TC07,P43034,Q15102,Q9UJY5,P15586,Q5H9R7,Q9UID3,P55327,Q9NZZ3,Q8TD16,P31751,P61923,P61163,O00203,O43237,Q9UNS2,Q04917,Q13409,A2RRP1,Q92905,P04350,Q9UBC2,Q9UN37,P48444,P47755,O43617,Q12955,Q4KMP7,Q07866,Q9H9H4,P24390,Q9UPT5,Q9Y496,O60664,O95721,P35606,P53621,Q7L5N1,Q92734,Q8IUR0,Q92783,Q16706,O60343,Q01968,P63104,Q9UBF2,Q9UJW0,Q9NQT8,P27348,P62330,P09497,Q15436,O60749,P11233,Q5VZ89,Q9NVG8,Q9UP83,Q14677,P31946,O00461,P83436,Q9H3P7,Q9Y296,Q9UNF0,Q9Y6G9,Q9Y6Y8,Q92572,Q9BUF5,Q9Y5X3,Q8N6T3,Q9BXS5 88 +Fceri mediated mapk activation 0.39664856702019 0.4843366951977497 0.6281469375465831 1.0 0.8349188138495799 7 Q16512 1 +Deadenylation of mrna 0.3175781170675453 0.481484762267188 0.6301720069781616 1.0 0.8349188138495799 15 Q5TAX3 1 +Vldlr internalisation and degradation 0.3958455236980637 0.4809921441904247 0.6305220820410213 1.0 0.8349188138495799 7 Q00610,Q96CW1,P53680,P63010,O94973,O95782 6 +G alpha i signalling events 0.2826306850323357 0.4759210964538572 0.6341305918896145 1.0 0.8389019288539692 26 P30154,P30153,P04083,Q9NRV9,Q14738,O43865,Q86YR5 7 +Tp53 regulates transcription of cell cycle genes 0.3223664694893355 0.4685166889053045 0.6394151392451293 1.0 0.8421584554331522 14 A5YKK6,P12004,Q86X55,P24941,O14965,Q99873,P06493 7 +Cdc42 gtpase cycle 0.2529224486875078 0.4682492083026788 0.6396063859803682 1.0 0.8421584554331522 37 Q9UQB8,Q96HP0 2 +Nef mediated cd8 down regulation 0.416788534659248 0.4636436547584039 0.642903072188016 1.0 0.8425286977923624 6 Q96CW1,P53680,P63010,O94973,O95782 5 +Nef mediated cd4 down regulation 0.416788534659248 0.4636436547584039 0.642903072188016 1.0 0.8425286977923624 6 Q96CW1,P53680,P63010,O94973,O95782 5 +Rna polymerase iii transcription 0.3418885567666417 0.4626520767370141 0.6436137742331933 1.0 0.842564535445358 11 Q9NVU0 1 +Infectious disease 0.28617956841351 0.4610225871150624 0.6447824000583939 1.0 0.842564535445358 357 Q99720,O75351,P49721,P28070,Q13200,Q15370,Q16539,P20618,Q9BVA1,Q9UQB8,P07437,Q96PU5,P39748,P84098,O43865,O75832,P04150,Q13546,P18858,Q9HD42,O60942,P05387,P32969,P28072,P49720,Q93034,P62942,Q99570,P62917,P36507,P15880,P28074,P62826,P46108,P61247,P61513,P48729,Q96JJ3,Q9NZZ3,P60900,P25788,P08238,P62899,Q99436,P39019,Q12873,P83731,Q13177,P62750,P61289,P28066,O43237,P62081,Q9H267,Q13409,P62277,P62266,P05388,P29083,O00505,P04350,P46778,Q9UN37,P51665,P46783,P27635,P18621,Q15008,Q99460,P48556,Q9H9H4,P62333,P62841,Q9Y5B9,P63208,O00232,P83916,P13010,P17612,P23396,P19525,P17980,P62861,P62241,P62195,P25789,P62906,P39023,Q8NEB9,Q92783,P83881,Q16706,Q02790,Q99873,P52294,P55199,Q9UER7,Q96SB4,P62753,P23193,P13984,P08708,P26373,P25786,P07900,O43242,O15144,P62191,Q9UNM6,P62269,Q02750,Q08945,P62847,Q9Y6G9,P25787,P49841,Q9BUF5,Q9UL46,Q8WX92,Q14241,Q9BXS5 121 +Signaling by ntrk2 trkb 0.446774570702812 0.4505259022476187 0.6523312815804445 1.0 0.8469394055463578 5 Q06124 1 +Signaling by pdgf 0.3628357951708021 0.4454895563901564 0.6559660054025676 1.0 0.8500783947563886 8 P46108,P46109 2 +Downstream signal transduction 0.3628357951708021 0.4454895563901564 0.6559660054025676 1.0 0.8500783947563886 8 P46108,P46109 2 +Heme signaling 0.4109928969720466 0.4414816126551188 0.6588643701662387 1.0 0.850861768883127 6 Q86X55,O14980,Q15648 3 +Leishmania infection 0.241649663453619 0.43850729547408 0.661018582787833 1.0 0.8526712466801503 45 Q9UQB8,Q16539,O43865 3 +Met activates ras signaling 0.5715955581531146 0.4337538900609508 0.6644671685681609 1.0 0.8563289986067535 3 P62993,Q96P70 2 +Tp53 regulates transcription of dna repair genes 0.2542973869939629 0.4261846551869561 0.6699732979383324 1.0 0.8596060895960959 31 P18074,Q9NVI1,P55199,Q08945,Q9BXW9,Q9Y5B9,Q14241,Q8IXH7,Q13535,P23193,P13984,Q15370,Q8WX92 13 +Glucuronidation 0.5673205099045094 0.4210673053666731 0.6737059349528489 1.0 0.8626647031431072 3 O60701 1 +Assembly of the orc complex at the origin of replication 0.3792425152537838 0.4136673163345397 0.6791177662895476 1.0 0.8680032200425415 7 P52294,O60684,Q9UBD5 3 +Inlb mediated entry of listeria monocytogenes into host cell 0.4031669885638942 0.4121950381361381 0.6801964737082264 1.0 0.8685872703568486 6 Q99961,Q92783,O14964 3 +Late endosomal microautophagy 0.3368020559302747 0.4090254922689807 0.6825209533928969 1.0 0.870759609031851 10 Q9H9H4,Q99497,Q99816,P08670,O60664 5 +Cd28 dependent vav1 pathway 0.4340009178994735 0.4059486683487675 0.6847803173263438 1.0 0.8711456783313853 5 Q16512 1 +Intra golgi traffic 0.2957501484205791 0.4056226232491514 0.6850199035488833 1.0 0.8711456783313853 16 Q9UP83,O00461,O95721 3 +Activation of rac1 0.4337867719353152 0.4052171553877749 0.6853178958383626 1.0 0.8711456783313853 5 Q16512 1 +Rna polymerase ii transcribes snrna genes 0.2504383987313828 0.4000065153043048 0.6891517180015438 1.0 0.873634255942066 31 P55199,Q9NVH2,Q96P16,Q9NQG5,P29083,Q9H814 6 +Platelet homeostasis 0.3204120808266032 0.3955316733130311 0.6924505513022514 1.0 0.8748629857657537 12 Q16539,Q06124,P30154,P30153 4 +Irak1 recruits ikk complex 0.5578609000584287 0.3935972045750093 0.6938784454033278 1.0 0.8748629857657537 3 P51617,O15111 2 +Ticam1 rip1 mediated ikk complex recruitment 0.5578609000584267 0.3935972045750032 0.6938784454033322 1.0 0.8748629857657537 3 O15111,Q13546 2 +Arms mediated activation 0.5574250529836415 0.3923520538289497 0.6947981071592868 1.0 0.8752326020753144 3 P46108 1 +Fructose metabolism 0.560327198364018 0.3877107479304275 0.6982301010783099 1.0 0.8753679989611475 2 Q00796 1 +Clathrin mediated endocytosis 0.2286436659241721 0.3874377353786709 0.6984321721588926 1.0 0.8753679989611475 61 Q9UBC2,Q9UNS2,Q7L5N1,Q92783,Q8N6T3,P61201,Q9UNF0,Q01968,Q9UBW8,Q92905,P20645 11 +Caspase activation via extrinsic apoptotic signalling pathway 0.5548846192567916 0.3851311987791413 0.7001402141941877 1.0 0.8753679989611475 3 Q13546 1 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3713976097406461 0.3831682696185538 0.701595003129821 1.0 0.8753679989611475 7 Q8NEB9,Q06124,Q99570 3 +Insulin receptor signalling cascade 0.3711052644799481 0.382049217667561 0.7024248581499257 1.0 0.8753679989611475 7 Q8NEB9,Q06124,Q99570 3 +Ikba variant leads to eda id 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.8757078040153269 2 O15111 1 +Polymerase switching 0.3105482351471169 0.3794125180178258 0.7043815562410081 1.0 0.8757078040153269 13 P35251,P49642,P12004,P40938,P40937,P49643 6 +Interleukin 21 signaling 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.8851908446543635 2 P42224 1 +Interleukin 9 signaling 0.5524393806602521 0.3646453777808576 0.7153761371616019 1.0 0.8851908446543635 2 P42224 1 +Interleukin 15 signaling 0.5524393806602462 0.3646453777808398 0.7153761371616152 1.0 0.8851908446543635 2 P62993 1 +Alk mutants bind tkis 0.3642890394751911 0.3563298386336875 0.7215935658902888 1.0 0.8891578186983264 7 O43815 1 +Gap junction degradation 0.3875402164375442 0.3561016103413037 0.7217644712984268 1.0 0.8891578186983264 6 Q00610,P50570,Q96CW1,P09497,P09496 5 +Eph ephrin mediated repulsion of cells 0.3015826494724438 0.3396994808364687 0.7340828527527066 1.0 0.8979980256528293 13 P98172,Q00610,P07948,O95782,Q96CW1,P07947,P53680,P63010,P09497,P09496,O94973,Q92542 12 +Interleukin 6 family signaling 0.4366696528600094 0.337895808796938 0.7354417060959431 1.0 0.8980874680210074 4 Q06124 1 +Interleukin 6 signaling 0.4366696528600094 0.337895808796938 0.7354417060959431 1.0 0.8980874680210074 4 Q06124 1 +Oncogenic mapk signaling 0.2358151579290424 0.3329920331088581 0.7391402969729988 1.0 0.9011176590398178 32 P41240,Q7Z569,Q02750,P51114,P36507,P18206,P30086,O00203,P10398,Q9NRY5,P31946,P46940 12 +Irs mediated signalling 0.3799786070545474 0.3301959579587454 0.7412519008081966 1.0 0.9022561120389864 6 Q8NEB9,Q06124,Q99570 3 +Cytosolic sensors of pathogen associated dna 0.277301948915661 0.3293606790031134 0.7418830848579141 1.0 0.9022561120389864 18 P19474 1 +Golgi associated vesicle biogenesis 0.2343357367486891 0.3248176881110474 0.7453190566492796 1.0 0.9044473893997594 33 Q9H3P7,O00203,Q14677,Q01968,Q9Y5X3,Q92572,O60749 7 +Muscle contraction 0.2568974113963488 0.3235197478778888 0.7463016543272136 1.0 0.9044473893997594 26 P04083,O43865,Q16512,O60504 4 +Nade modulates death signalling 0.536955886649152 0.3215182181624925 0.7478177084634421 1.0 0.9052871219440456 2 P62258 1 +Scavenging by class f receptors 0.4296989184449112 0.317293055226015 0.751021246463095 1.0 0.9068078490137802 4 Q9Y4L1,P07900,Q92598 3 +The role of nef in hiv 1 replication and disease pathogenesis 0.3014942865514081 0.3149653479454583 0.7527879641157753 1.0 0.908072155719392 12 Q10567,P04439,Q13177,Q96CW1,Q9UI12,P53680,P63010,O43747,O94973,Q9BXS5,O95782 11 +Regulation of signaling by cbl 0.351733640641933 0.3109230515378043 0.755859119831336 1.0 0.908072155719392 7 P46108 1 +Trna modification in the mitochondrion 0.403285144441325 0.3069358626703742 0.7588921912678819 1.0 0.9100192199152196 5 Q969Y2 1 +Rhobtb gtpase cycle 0.2386472499010967 0.300269959327009 0.763971245566827 1.0 0.9133496434043664 30 Q13098,P08238,O43396,O75116,Q16543,P78371,P08670,Q13464,Q9BT78,P61201,P12814,Q8IYB3,P07900,Q12792,Q8N684 15 +Parasite infection 0.2478184959234603 0.2920077023927351 0.770280734850509 1.0 0.9181588622748814 27 Q9UQB8 1 +Transcriptional regulation of white adipocyte differentiation 0.2895140408608579 0.2892969571631444 0.7723541406483558 1.0 0.9190619544171662 13 Q86X55,Q96EK7 2 +Erbb2 regulates cell motility 0.5205959684487441 0.2792213446143236 0.7800749641664817 1.0 0.9223630258155066 2 O60610 1 +Role of phospholipids in phagocytosis 0.3934333362156318 0.277924287629652 0.781070479269681 1.0 0.9223630258155066 5 O43865 1 +Signaling by ptk6 0.2805721873327402 0.2760421430921762 0.7825156977367633 1.0 0.9225100672896696 14 P04150 1 +Ionotropic activity of kainate receptors 0.5119812974868382 0.2734024322130303 0.7845438833502947 1.0 0.9233427169674489 3 Q15334,Q92796 2 +Nrcam interactions 0.5119812974868382 0.2734024322130303 0.7845438833502947 1.0 0.9233427169674489 3 Q15334,Q92796 2 +Signal transduction by l1 0.3028787106871726 0.2708150133860799 0.7865333122200535 1.0 0.9234697730548777 10 P36507,Q16512,Q02750 3 +Signaling by egfr in cancer 0.3898984007945193 0.2678672901682069 0.7888014725268377 1.0 0.9234697730548777 5 Q16543 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.3898984007945193 0.2678672901682069 0.7888014725268377 1.0 0.9234697730548777 5 Q16543 1 +Constitutive signaling by egfrviii 0.3898984007945193 0.2678672901682069 0.7888014725268377 1.0 0.9234697730548777 5 Q16543 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.2653688374419656 0.2672468523870352 0.7892791045293657 1.0 0.9234697730548777 17 Q15436,O95486,Q6P179 3 +Vesicle mediated transport 0.2571072698957816 0.2640440466859605 0.7917459783883873 1.0 0.9255808634381398 274 Q7Z6M1,O75351,O15260,P61201,Q14203,Q9BVA1,Q9Y678,O95486,O95487,Q8IWJ2,Q5VZE5,Q9NZ32,Q9UKS6,Q15042,Q9UBW8,P20645,O60763,Q8TC07,P43034,Q15102,Q9UJY5,P15586,Q5H9R7,Q9UID3,P55327,Q9NZZ3,Q8TD16,P31751,P61923,P61163,O00203,O43237,Q9UNS2,Q04917,Q13409,A2RRP1,Q92905,P04350,Q9UBC2,Q9UN37,P48444,P47755,O43617,Q12955,Q4KMP7,Q07866,Q9H9H4,P24390,Q9UPT5,Q9Y496,O60664,O95721,P35606,P53621,Q7L5N1,Q92734,Q8IUR0,Q92783,Q16706,O60343,Q01968,P63104,Q9UBF2,Q9UJW0,Q9NQT8,P27348,P62330,P09497,Q15436,O60749,P11233,P07900,Q5VZ89,Q9NVG8,Q9UP83,Q14677,P31946,O00461,P83436,Q9H3P7,Q9Y296,Q9UNF0,Q9Y6G9,Q9Y6Y8,Q92572,Q9BUF5,Q9Y5X3,Q8N6T3,Q9BXS5 89 +Interleukin 3 interleukin 5 and gm csf signaling 0.2855131644895254 0.2535095435561845 0.7998744872961252 1.0 0.9319638521707146 12 P17612,Q06124,P46108,P46109 4 +Lipophagy 0.4054370067231926 0.2507413339423535 0.8020141014104323 1.0 0.9333322614993856 4 P54619,O60664,P11142 3 +Regulation of mecp2 expression and activity 0.2846177598088851 0.2502614791775489 0.802385143923237 1.0 0.9333322614993856 12 P42858 1 +Telomere maintenance 0.2174867070014419 0.2399478658551787 0.8103706729787343 1.0 0.9410538904000764 41 P28340,P35251,P49642,Q9UER7,P12004,Q9NYB0,P35244,Q5H9R7,P40938,P40937,P15927,P24941,P49643,P18858,P39748 15 +Synthesis of diphthamide eef2 0.3997960196352845 0.2364805137152944 0.8130598263315072 1.0 0.9418280077820196 4 Q9BTV6,P13639 2 +Interferon alpha beta signaling 0.2980654018080728 0.2315189299880641 0.8169116808772083 1.0 0.9425780548242936 9 Q13325,Q9Y3Z3,P42224,Q06124,P61221 5 +Copii mediated vesicle transport 0.2180208411616165 0.2285372746609973 0.8192285817402878 1.0 0.9425780548242936 34 O43617,Q8IUR0,Q5H9R7,Q9Y296,O95486,O95487,Q15436,Q9Y6Y8 8 +Regulated necrosis 0.25131526802816 0.2272675534473845 0.8202157015965912 1.0 0.9425780548242936 20 P09429,P98170 2 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.3741884580378256 0.2255281234641075 0.8215684494907907 1.0 0.9425780548242936 5 Q13546,Q14258 2 +Striated muscle contraction 0.3725461506594282 0.2213304166957725 0.824835168104634 1.0 0.9437303274710676 5 P67936 1 +Mitotic spindle checkpoint 0.2101125152750212 0.2192395492660152 0.8264634489387135 1.0 0.9444032686428696 55 Q15691,P30154,P30153,Q92674,Q9HBM1,Q14738,Q9Y266,P43034,Q9P258,Q6P1K2,Q9Y6G9,O75122,Q7Z460,O43237 14 +Protein methylation 0.3214135804439024 0.2130772498927806 0.8312667091351882 1.0 0.9457650635245434 7 O60678,P15880 2 +Neutrophil degranulation 0.2131499585691756 0.2129672085478186 0.8313525397338148 1.0 0.9457650635245434 177 P17931,O75874,P15586,P51665,Q9UNM6,O15260,Q5T4S7,Q13200,Q15008,Q99460,P09429,Q16539,P20618,Q96G03,P78371,O00232,P07741,P13010,Q9Y6G9,P07437,Q9BRF8,P14174,P30740,P14618,P17980,P46976,O95721,P04080,P06744,P08238,Q13442,P53990,Q99436,P06737,P36871,P25787,P42785,Q9NZ32,Q99439,Q7Z6Z7,P22392,P28066,P30041,P00491,P18669,Q86VP6,Q9BXS5,O43242 48 +Sema4d in semaphorin signaling 0.3011413520632052 0.2119019228569826 0.8321835504383872 1.0 0.945940130156572 8 Q7Z406,O75116,P61586,Q13464,P35579,P35580,P60660 7 +Nr1h2 and nr1h3 mediated signaling 0.3376436176677144 0.2023603403257423 0.8396350308032561 1.0 0.9530449636353197 6 O15379,Q9HCE1,Q8NB78 3 +Grb2 sos provides linkage to mapk signaling for integrins 0.47457627118642 0.1934727691497996 0.8465887302148327 1.0 0.9584152804782182 3 P62993,Q9Y490 2 +Signaling by erbb2 0.2503711513061032 0.1823150405524909 0.8553354958382866 1.0 0.9659690280404902 15 Q93034,Q9Y243,P31751,Q16543,P40818,O60610,P07900 7 +Negative regulation of met activity 0.2870044509994832 0.1697157752512711 0.8652336671984253 1.0 0.9732930994577378 8 Q92783 1 +Trna processing in the mitochondrion 0.369774919614146 0.1688103954682036 0.8659457812786531 1.0 0.9732930994577378 4 Q9BQ52,Q99714,Q7L0Y3 3 +Runx2 regulates osteoblast differentiation 0.3691902952353118 0.1676337909985452 0.8668713859810036 1.0 0.9734882043532652 4 O15379,P06400,P28482 3 +Rab gefs exchange gtp for gdp on rabs 0.2121009390404286 0.1651222837553614 0.8688477338568521 1.0 0.9740181005316912 30 P62258,Q7Z392,P61020,Q9UL25,Q5VZ89,P50395,P31751,O43617,Q6IQ22,Q8IUR0,Q9Y296,Q15042 12 +Rho gtpases activate paks 0.2578376794608739 0.1634906519913068 0.870132132758447 1.0 0.9740181005316912 12 Q7Z406,P62140,Q13177,P21333,P63000,Q14247,P60953,P35579,P35580,P60660,Q16512 11 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.3198250800613746 0.1582916981475058 0.874226949590514 1.0 0.9762145456153316 6 P09429 1 +Signaling by mapk mutants 0.461291264972266 0.156564250569753 0.8755882789234128 1.0 0.9762145456153316 2 Q99956 1 +Signal attenuation 0.4612912649722647 0.1565642505697504 0.8755882789234148 1.0 0.9762145456153316 2 P62993 1 +Ephrin signaling 0.3161115028072955 0.1498857304457531 0.880854769986567 1.0 0.9797405363624476 6 Q16512 1 +Serine biosynthesis 0.4504820333041269 0.1395610016957898 0.8890068551246524 1.0 0.9824269399893596 2 Q9Y617 1 +Pka activation in glucagon signalling 0.3516515638702121 0.1348899137439551 0.8926989143310131 1.0 0.9824269399893596 4 P13861,P17612,P10644 3 +Pka mediated phosphorylation of creb 0.3516515638702121 0.1348899137439551 0.8926989143310131 1.0 0.9824269399893596 4 P13861,P17612,P10644 3 +Creb1 phosphorylation through the activation of adenylate cyclase 0.3516515638702121 0.1348899137439551 0.8926989143310131 1.0 0.9824269399893596 4 P13861,P17612,P10644 3 +Transcriptional regulation by tp53 0.1837169488735361 0.134527946303546 0.8929851139850313 1.0 0.9824269399893596 138 Q9NVI1,P30153,P42345,P30044,Q9UQ84,P61981,P42771,P40938,P15927,P24941,Q13526,Q15370,P31946,Q16539,P30154,Q08945,Q9Y5B9,Q13535,O60921,P06744,P00390,P78356,P31751,Q12873,P35244,P63104,Q99873,Q00535,Q8WX92,P55199,Q9BXW9,Q9UER7,Q9HCE1,Q14241,Q04917,P27348,Q86X55,P23193,P19784,P13984,O14965,Q9NQ88,P06493 43 +Displacement of dna glycosylase by apex1 0.4371338292351596 0.1311743927210092 0.8956373525500791 1.0 0.983652029490928 3 P13051 1 +Ovarian tumor domain proteases 0.2635936019774909 0.128425626477779 0.8978121520770317 1.0 0.9837420985660698 9 P06493,Q13546,Q96FW1 3 +Copi dependent golgi to er retrograde traffic 0.1948989881789491 0.1266211303946378 0.8992402719175885 1.0 0.9837420985660698 50 P35606,P24390,P48444,Q9BVA1,P53621,Q9Y496,Q9UBF2,P61923,Q9Y678,O15260,Q8N6T3,Q9BUF5,A2RRP1,Q07866,P04350 15 +Dual incision in tc ner 0.1953336797973671 0.1198012671206546 0.9046405781568648 1.0 0.987550057595952 35 P18074,Q07864,P56282,P35251,Q13620,P12004,P35244,P40938,P40937,P15927,Q9ULR0,P23193,P28340,P27694 14 +Microrna mirna biogenesis 0.240915728000307 0.1195471890101235 0.9048418566376656 1.0 0.987550057595952 12 Q9UPY3 1 +Signaling by fgfr4 in disease 0.4297399941571764 0.111450114939108 0.9112594215803826 1.0 0.9906843672745482 2 P62993 1 +Estrogen dependent gene expression 0.1964498212091887 0.1046706174876905 0.9166371777066726 1.0 0.9935735264092082 30 O14646,Q86X55 2 +Chromosome maintenance 0.1887499363655738 0.0997703331679912 0.9205266612062286 1.0 0.9961082460922552 45 P49642,Q92674,Q9NYB0,P35244,Q5H9R7,P15927,P24941,P18858,P39748 9 +Diseases of mismatch repair mmr 0.410286382232599 0.0973658103753258 0.9224358950587744 1.0 0.9966302748624192 3 P52701,P43246 2 +Rhobtb2 gtpase cycle 0.2108513617705819 0.0914443058811643 0.9271395581957932 1.0 0.9980128936235672 20 P08238,O43396,Q16543,P78371,Q8IYB3,P12814,Q12792,P07900 8 +Ngf stimulated transcription 0.4027829172276801 0.0894599705469645 0.9287163648608714 1.0 0.9980128936235672 3 Q00535 1 +Suppression of phagosomal maturation 0.2678564012646339 0.0874244298150835 0.9303341515344364 1.0 0.9989829436538108 7 P52294,Q9H267 2 +Constitutive signaling by overexpressed erbb2 0.3150181681703697 0.0822337109234488 0.9344608667762132 1.0 1.0 4 Q16543 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.1852038356417911 0.080424319573646 0.9358997853274896 1.0 1.0 39 Q9UPT5,Q9BVA1,P31751,Q9Y496,P04350,P61981,Q04917,P27348,Q9BUF5,O60343,P11233,P63104,P31946 13 +Response to elevated platelet cytosolic ca2 0.1821345540082029 0.073504696513757 0.9414045069094286 1.0 1.0 34 Q96JJ7,P07737,Q9NTK5 3 +Triglyceride metabolism 0.2434884401521673 0.0710275425743469 0.9433758350390992 1.0 1.0 8 Q01469,P62140,P43304,P17252,P62136,O60664,P17612 7 +Regulation of ifng signaling 0.3044954084975533 0.0708511734078561 0.9435162036342022 1.0 1.0 4 Q06124 1 +Advanced glycosylation endproduct receptor signaling 0.2430645433838991 0.0702995558770857 0.9439552359930768 1.0 1.0 8 P09429,P17931 2 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.3798947983635286 0.0692052379288067 0.9448262538420606 1.0 1.0 3 Q5TKA1,P06493 2 +Repression of wnt target genes 0.3798947983635281 0.0692052379288061 0.9448262538420612 1.0 1.0 3 P56545,Q13363 2 +P75ntr negatively regulates cell cycle via sc1 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 1.0 3 O15379,Q92769 2 +Transcriptional regulation by mecp2 0.2036451247902863 0.0652093963582994 0.9480072798422404 1.0 1.0 16 P42858 1 +Rhobtb1 gtpase cycle 0.1982252411992255 0.0629239185786993 0.9498270883111954 1.0 1.0 20 O43396,O75116,P08670,P78371,Q13464,Q9BT78,P61201,Q8IYB3,Q8N684 9 +Signaling by erbb2 ecd mutants 0.2827300352240129 0.061747255967798 0.9507641069195996 1.0 1.0 5 Q16543 1 +Signaling by erbb2 in cancer 0.2827300352240129 0.061747255967798 0.9507641069195996 1.0 1.0 5 Q16543 1 +Triglyceride catabolism 0.2498537156231741 0.0593679533027075 0.9526590375808436 1.0 1.0 7 Q01469,P62140,P17252,P62136,O60664,P17612 6 +Traf6 mediated irf7 activation 0.3605024832018682 0.0552847366103679 0.9559116219888676 1.0 1.0 2 Q14258 1 +Traf3 dependent irf activation pathway 0.3605024832018682 0.0552847366103679 0.9559116219888676 1.0 1.0 2 Q14258 1 +Phase i functionalization of compounds 0.1985232111072704 0.0552712638085154 0.9559223553182346 1.0 1.0 16 Q16850 1 +Er quality control compartment erqc 0.3579777907656375 0.0547475908570451 0.9563395541689916 1.0 1.0 3 Q9UBV2,Q9GZP9 2 +Rhov gtpase cycle 0.1962031329848072 0.0526356163394342 0.9580222385568672 1.0 1.0 17 P67936,Q13177,Q93008,P06753,Q16512,P46940 6 +Acetylcholine regulates insulin secretion 0.3506721215663299 0.0508759694144258 0.9594243543348256 1.0 1.0 3 P17252,P29966 2 +Sars cov infections 0.1780213719121727 0.0477970686168381 0.9618779727929528 1.0 1.0 65 P62942,P04150,Q99720 3 +Negative regulation of flt3 0.3333333333333301 0.045311333803424 0.963859153649312 1.0 1.0 2 P41240 1 +Endosomal vacuolar pathway 0.3345996493278727 0.0438165822956952 0.9650506090179534 1.0 1.0 3 Q9UIQ6,P04439 2 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3345996493278722 0.0438165822956949 0.9650506090179536 1.0 1.0 3 P04439,P05556 2 +Death receptor signalling 0.175955877403645 0.0437169607623153 0.96513001940839 1.0 1.0 29 P62258,P49327,P98170,Q13107,O15379,O15111,Q9H8V3,Q15750,P51617,O95429,Q13546,Q92542 12 +Influenza infection 0.182398172236778 0.0425593802472178 0.9660527759985644 1.0 1.0 125 P46778,O14980,P46783,P27635,P62917,P18621,P46781,P15880,P62269,P62826,P61247,P61513,P62841,P62847,P23396,P19525,P62861,P62241,P84098,P62899,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P52294,P05387,P32969,P62753,P62277,P62266,P05388,P13984,O00505,P08708,P26373,P07900 39 +Neurexins and neuroligins 0.2096632503660332 0.0398535272827567 0.9682099014984076 1.0 1.0 10 Q14168,P11171,Q92796,O43491,Q96HC4,Q9HCM4,Q9Y2J2,Q9UJU6,Q15334 9 +Response of mtb to phagocytosis 0.1904482859654177 0.037800432900327 0.9698467992158166 1.0 1.0 12 P52294,O14964,Q9H267,P06733,P23246,P00558,Q14974,Q9UI12,P28482,P20339,P49840 11 +Infection with mycobacterium tuberculosis 0.1904482859654177 0.037800432900327 0.9698467992158166 1.0 1.0 12 P52294,O14964,Q9H267,P06733,P23246,P00558,Q14974,Q9UI12,P28482,P20339,P49840 11 +Regulation of ifna signaling 0.3149555566973772 0.0375300480456602 0.970062382141374 1.0 1.0 3 Q06124 1 +Activation of smo 0.2576811564132854 0.0373569964540836 0.9702003605763528 1.0 1.0 4 P48729 1 +Gp1b ix v activation signalling 0.2857142857142772 0.0371961428081827 0.9703286140790106 1.0 1.0 2 P63104 1 +Cellular responses to stimuli 0.2494605235886813 0.0323737165650471 0.974174022640701 1.0 1.0 334 P49721,P25685,O00716,P28070,Q13200,Q14203,Q15370,Q16539,Q9HC52,P20618,Q9BVA1,P31689,P84098,P35244,Q99615,P04792,O75832,P04150,Q9NZ32,P05387,P32969,P28072,Q86X55,Q13309,P49720,P62917,P15880,P15927,P28074,P24941,P61247,P61513,Q9NYB0,Q13535,P60900,P25788,P08238,P62899,Q99436,P39019,P83731,P61163,O95817,P62750,P61289,P28066,O43237,P62081,Q9HCE1,Q13409,P62277,P62266,P05388,O75190,P04350,P51858,P46778,P51665,P46783,P47755,P42345,P27635,P20042,P18621,P42771,Q15008,Q96B36,Q99460,P48556,P62333,P62841,Q06210,Q16763,P63208,O00232,O14773,P23396,P17980,P62861,P62241,P62195,P25789,P31948,P62906,P39023,Q92616,P83881,Q02790,Q9UJW0,Q9Y2L1,P62753,P19784,P08708,P08243,P25786,P26373,O43242,P07900,P62191,O14980,Q99543,P30044,Q9UNM6,P46781,P62269,O95429,Q00534,P62847,Q9Y6G9,P00390,P25787,P49841,P53004,Q9BUF5,Q9UL46,P30041,O60884,Q8N6T3 118 +Prevention of phagosomal lysosomal fusion 0.2429422541559854 0.0315125814045797 0.9748607586188072 1.0 1.0 4 Q9H267 1 +Abc transporters in lipid homeostasis 0.2530683810637101 0.0287756385855558 0.9770435304248596 1.0 1.0 3 P40855,P28288 2 +Regulation of tp53 activity through association with co factors 0.2451797392970226 0.028377360496807 0.9773611806350236 1.0 1.0 3 P31751 1 +Assembly of the hiv virion 0.2413793103448329 0.0282180465246002 0.977488243909852 1.0 1.0 3 Q9H9H4,Q99816 2 +Nuclear events stimulated by alk signaling in cancer 0.1870377165171506 0.0259485811411663 0.9792983509284288 1.0 1.0 11 Q9HC35,P63208 2 +Sensory processing of sound by outer hair cells of the cochlea 0.1794711219395942 0.0259230118423868 0.9793187454166664 1.0 1.0 14 P15311,P26038,Q6IBS0,Q9Y2J2 4 +Syndecan interactions 0.2093567251462001 0.0193026212162666 0.9845996928909012 1.0 1.0 5 Q9Y296,P12814,P05556,P17252 4 +Rho gtpases activate iqgaps 0.1634925285672318 0.0189945716286447 0.9848454358425948 1.0 1.0 12 P46940,Q9BVA1,Q13885,P68371,P35221,Q9BUF5,P60953,Q13576,P63000,P04350,Q86VI3 11 +Eph ephrin signaling 0.1553330847575127 0.0111861867066937 0.9910749004669596 1.0 1.0 35 O15144,O15145,P61160,O75116,Q92747,Q13177,Q13464,P23528,P09497,O00560,O94973,P60660,Q16512,Q92542 14 +Signaling by fgfr1 in disease 0.1327806114111587 0.0036257569924327 0.997107070812979 1.0 1.0 11 Q16630,P62993,P11274,P42224,O95429 5 +Fgfr1 mutant receptor activation 0.1556364130919336 0.0016502139495384 0.99868332036524 1.0 1.0 10 Q16630,P62993,P11274,P42224,O95429 5 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..09f157f44dae393608cb22a727a0c20e4785fa49 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of cell cycle factors", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCKDHA", "BCKDK", "BCL10", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRD7", "BRD8", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPI", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT7", "COA1", "COASY", "COG3", "COG4", "COG5", "COG7", "COG8", "COLGALT1", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTC", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH7", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFNB1", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESCO2", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM49B", "FAM91A1", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FOXK1", "FPGS", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INCENP", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISCU", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC1", "LRRC8A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K6", "MAP4K4", "MAPK1", "MAPK14", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "METAP2", "METTL1", "METTL14", "METTL3", "MFGE8", "MFN1", "MFN2", "MGA", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFKBIE", "NFRKB", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR3C1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NUB1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMF1", "PMPCA", "PMPCB", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "POFUT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R2", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFOX2", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF14", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SBF1", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORBS3", "SORD", "SORT1", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STX5", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF1", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TCTN3", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM115", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC21B", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UIMC1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "WAPL", "WARS", "WASF2", "WBP11", "WDR1", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AAMP", "AARS", "AASDHPPT", "ABCD3", "ABCE1", "ABCF1", "ABRAXAS2", "ACBD3", "ACP6", "ACTN1", "ACTR10", "ACTR1A", "ACTR2", "ADD1", "ADK", "ADO", "ADSL", "ADSS", "AGL", "AHCYL1", "AIMP2", "AIP", "AK6", "AKT1S1", "AKT2", "AKT3", "ALCAM", "AMPD2", "ANK3", "ANP32A", "ANXA1", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3S1", "APEX1", "APRT", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARL3", "ARPC1A", "ARPC2", "ARPC3", "AS3MT", "ASCC2", "ASCC3", "ASH2L", "ASNS", "ATIC", "ATP6V1H", "ATR", "AURKA", "BABAM1", "BAG3", "BAG4", "BAIAP2", "BCKDK", "BCL10", "BCR", "BICD2", "BLVRA", "BRAP", "BUB1B", "CAMK1", "CAND1", "CAPZA2", "CARM1", "CARS", "CASP3", "CBX1", "CBX8", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CDC25C", "CDC34", "CDC37", "CDC42", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CENPI", "CETN2", "CFL1", "CHAC2", "CHD1", "CHD1L", "CHD3", "CHD8", "CHKA", "CHMP1A", "CHMP5", "CHUK", "CKB", "CLASP1", "CLASP2", "CLINT1", "CLTA", "CLTB", "CLTC", "CNDP2", "CNN2", "CNOT1", "COG5", "COG7", "COMMD2", "COPA", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "CPPED1", "CPSF6", "CPSF7", "CRK", "CRKL", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CTPS1", "CTPS2", "CTTN", "CUL1", "CUL4B", "CUL5", "CYP51A1", "DAXX", "DBNL", "DCAF1", "DCAF16", "DCD", "DCP1A", "DCPS", "DCTN1", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DENND4C", "DERL2", "DHCR24", "DHCR7", "DHFR", "DIAPH1", "DIAPH2", "DICER1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC2", "DNAJC7", "DNM2", "DNMT1", "DNPH1", "DOCK6", "DPH7", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", 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pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome degradation 21 39 4.064687803797374 4.8096797889529697e-05 12.050970873786408 41.16504854368932 0.6913339882315582 0.5158259179783452 5.889337413827548 1.124286935861288 1.1356581007954978 0.3607938079641982 1.0 0.001740287381965 0.0001225386178253 2.251435456057573e-09 5.192359572985538e-15 +Translation factors 28 37 2.868808694071765 0.0041202092162766 11.012135922330096 36.407766990291265 0.237804702796095 0.5855996076835563 7.095899834901985 1.2400038615965827 1.0529950625688889 0.3465203977253575 1.0 1.0 1.0 0.1109177218711893 0.0080473050001108 +Alzheimers disease 40 87 2.7449966957032435 0.0060511506972127 18.929611650485437 83.0752427184466 0.8523996335219438 0.5089902911900335 9.09856474570077 6.061710858604258 1.0800674607776464 0.3865214102951685 1.0 0.0644351281380516 0.2914336378374108 0.0030073227610312 2.725003883715712e-05 +Alzheimers disease and mirna effects 40 88 2.654246982209915 0.0079485624612702 19.78640776699029 84.62864077669903 0.8675405351918691 0.5019659822826982 9.06411947478317 6.212690980603589 1.0744065053186531 0.3869842050583563 1.0 0.0668087997235459 0.2993265060905456 0.003403443148949 3.503338562714592e-05 +Retinoblastoma gene in cancer 28 51 2.5623285934798736 0.0103972895723583 13.902912621359222 46.932038834951456 0.0759370557009261 0.6359290150115153 7.276127428212639 3.8231846023107767 0.92369516627564 0.3276008399122643 1.0 0.3378643758427397 0.2037147080402499 0.1615757358664762 0.0093945593522846 +Transsulfuration and onecarbon metabolism 2 18 2.557135498174926 0.010553809918572 5.589805825242719 17.91990291262136 -0.1687240570825596 0.5592156012144385 3.582480694080739 1.3056605627563191 0.9310429100430764 0.3149189119180438 1.0 0.1155957163384056 0.0255840399150975 0.0244664942800011 0.1303826157459173 +Oxysterols derived from cholesterol 2 8 2.539383813599449 0.0111047923016895 2.254854368932039 7.33252427184466 0.1962044165430426 0.4767358733288924 1.826344624524478 1.1378784708655931 1.058988657917013 0.30869858242651 1.0 0.0028214739728005 0.0005309775927247 0.0075105395483816 0.0468003866103798 +Cholesterol biosynthesis with skeletal dysplasias 3 6 2.5169221311598475 0.0118384990260462 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 1.0 0.0325017468768143 2.930872407836843e-05 1.1289574774720508e-05 0.0001722011086768 +Parkinubiquitin proteasomal system pathway 19 34 2.514178296865843 0.011931009833741 15.601941747572816 35.157766990291265 -0.325879167431566 0.536922604645563 7.590668525024711 1.7465257785732904 1.1836499766651585 0.3562945902068221 1.0 1.0 0.4297892617739207 0.7612281573002204 0.0217195139585283 +Metapathway biotransformation phase i and ii 4 22 2.506276551386861 0.0122010148504254 5.674757281553398 21.74757281553398 1.0367643596879972 0.3247805075973627 2.26648088910968 1.8784337960788755 0.9302956939670612 0.2816826074355951 1.0 0.2471994937249445 0.1132051672598368 0.0150633583956732 0.0704094801772502 +Glutathione metabolism 1 7 2.494316208152933 0.0126200063700383 2.3519417475728157 6.143203883495145 -0.0475883211244437 0.4626181588106582 1.726414185053583 0.9302768286101702 1.0838595673401377 0.3130544273100991 1.0 0.0461123069087121 0.0921025797166938 0.0233125205204954 0.0106255777102749 +Glycogen synthesis and degradation 10 19 2.3964293758539736 0.0165556836080367 5.932038834951456 17.138349514563107 0.0858180918831263 0.6237092680917387 3.3544988945360084 2.121957603726881 0.8038216387295297 0.3016325841164752 1.0 1.0 1.0 0.0080316637526189 0.0008750939624126 +7oxoc and 7betahc pathways 2 9 2.334474354024256 0.0195708974212882 2.6310679611650487 9.114077669902912 0.3689449979304526 0.3795786079895399 1.6691971866165078 1.1881681559370796 1.206779545179813 0.2917372556940649 1.0 0.0024970154667983 0.000440337804097 0.0062969264366488 0.039942155971048 +Pyrimidine metabolism 13 41 2.332095968830187 0.0196956430781229 12.866504854368932 41.08495145631068 -0.4740766041152258 0.542883053780543 6.731259090913494 4.337135508042058 0.9366616894674172 0.3387222784656058 0.0076500588464239 0.3088995675544995 0.5305553861952955 0.2950347285537182 0.3298273388868034 +Serine metabolism 0 6 2.317973736390952 0.0204507484679541 1.672330097087379 6.191747572815534 0.2630162311849149 0.4754478187283169 1.3801334562481016 0.6643705352626476 0.995018076460528 0.2938020617563008 1.0 0.0370595951599339 0.0743799864466655 0.1788587842302525 0.3290745839784397 +Cytoplasmic ribosomal proteins 33 75 2.2808551622804165 0.0225570189315107 37.88106796116505 74.60194174757281 -1.2114565348655126 0.3153680511516359 14.36226619031951 1.4436994404226102 2.072543722473557 0.3695037094755983 1.0 1.0 1.0 0.3485252538284032 0.0086796345032239 +Met in type 1 papillary renal cell carcinoma 11 24 2.258010683131912 0.0239449934039364 6.614077669902913 19.62135922330097 -0.2595188610963719 0.5831956753680716 3.5953173258530375 2.80556487521085 0.8254112986130796 0.2993877791725989 1.0 1.0 0.4072036678679048 0.1435696883620607 0.0042820394936164 +Cytosine methylation 1 5 2.257471495411396 0.0239786286689218 2.0533980582524274 4.839805825242719 -0.0649747594084269 0.3077365108683944 1.3517565367896365 0.4045469252427314 1.4549970578233429 0.2999126289601936 1.0 0.0007650215967213 0.0031504918831051 0.0189506401306209 0.0677640175569944 +Fluoropyrimidine activity 1 14 2.255133619381389 0.0241249429737224 2.995145631067961 12.055825242718448 0.2455873922249624 0.5667192773025801 2.165478428304421 1.1013187366748804 0.8214654770745025 0.2923268247958593 1.0 0.1155957163384056 0.0255840399150975 0.1309570889500886 0.3630866560691931 +Vitamin d in inflammatory diseases 2 6 2.2401576538514294 0.0250806897071411 1.8222222222222224 4.125925925925926 -0.2294514250961556 0.4921323279891633 1.4326010187809954 2.079041670125438 1.1015138179341544 0.3169415518445094 1.0 0.0901405579438761 0.0155240337321844 0.0840389641709933 0.0705348016344186 +Hepatocyte growth factor receptor signaling 5 12 2.23623630824135 0.0253362960390841 4.339805825242719 11.398058252427184 -0.4477760377892401 0.5232906395895968 2.3256835222771195 1.791781701689569 0.8207234971187893 0.3025807302163325 1.0 1.0 1.0 0.5568666172945154 0.0743636419116672 +Disorders of folate metabolism and transport 0 7 2.1826372576265296 0.0290625337712633 2.1407766990291264 7.405339805825243 0.2461758429428204 0.4865736310743483 1.8887987086471552 0.7460384897720235 1.0129661604612583 0.3045362782095057 1.0 0.0550816697898294 0.1094892401774078 0.2559514735144251 0.4505109675601652 +Netrinunc5b signaling pathway 6 15 2.135068367600196 0.0327554260276059 4.985436893203883 13.138349514563108 -0.3084654111477944 0.5393389591257444 3.1560977431733845 2.1231011377102047 0.9121023842895238 0.3066243214203769 1.0 0.1564797373419447 0.2941077913158182 0.2179356607727124 0.2544916035409682 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0.0397956899879941 2.6990291262135924 5.781553398058253 -0.1004261267123182 0.5729334335609 1.8398762698812257 1.7378844170855112 0.8625985970560335 0.3025033972720732 1.0 0.1321770275159086 0.2518545844225215 0.1648346062433529 0.1773693871336699 +G1 to s cell cycle control 18 28 2.0486279741379496 0.0404985070586683 6.900485436893204 24.733009708737864 0.2427705123410361 0.6554568890773506 4.5732760832124555 3.009947532023907 0.8058923051029326 0.3212929414660505 1.0 1.0 0.4297892617739207 0.7612281573002204 0.3116472395700642 +Cellular proteostasis 4 5 2.0249870114434585 0.0428686979562704 2.0679611650485437 4.271844660194175 0.5264789683544518 0.4206045803169084 1.1385746149601492 0.8469726185929765 1.0177721083239633 0.3027668715946303 1.0 1.0 1.0 0.0002693258491638 7.675515939222757e-05 +Onecarbon metabolism 1 15 1.989445152750973 0.046652090007748 4.570388349514563 13.985436893203884 -0.1942513007477925 0.5118698382115187 3.138764342341978 1.1015353598183553 1.0158004909633338 0.315636351329833 1.0 0.1071891284628969 0.2070995190727305 0.1147066696002357 0.3271248077551284 +Physiological and pathological hypertrophy of the heart 0 6 1.986236133615627 0.0470071104268949 2.7936893203883497 6.58252427184466 -0.4149282392767046 0.5430956049866076 1.7718562973417555 1.35477775087475 0.8160778504093061 0.2906489833139308 1.0 0.0901405579438761 0.1758008751515455 0.3891747515056749 0.631511633602643 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..748dd631aec898d8d43d61634819706fc1893db4 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 605, + "title": "Average number of proteins per term", + "value": 11.72892561983471 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ba282d9bdbbe46a8788250082434f323bd2659ee --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..56069608e3fde08645ea82967efae08155827956 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,246 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome degradation 0.6719436475982191 4.064687803797374 4.8096797889529697e-05 0.0286799559935451 0.029098562723166 39 P51665,P49721,Q9UNM6,P28070,P28074,P48556,P62333,P20618,P60900,P25788,P25789,Q99436,P25787,O75832,Q9UL46,P46934,P28066,P28072,P49720,P25786,O43242 21 +Translation factors 0.5261007124695916 2.868808694071765 0.0041202092162766 0.9177404677716222 0.2266115068952157 37 P24534,Q14232,P20042,P60228,P13639,O75822,P63241,P23588,Q9NR50,Q14240,Q15056,P19525,Q05639,O75821,O75153,Q14152,P06730,P26641,P29692,Q04637,P60842,P62495,O15371,P49770,O60841,P55010,Q13144,P55884 28 +Alzheimers disease 0.4242413872678779 2.7449966957032435 0.0060511506972127 0.97457614894555 0.2614961551295505 87 Q99570,P51665,P42345,P36507,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q07866,Q99460,P48556,P48729,Q02750,P20618,Q9BVA1,P62333,O00232,P60900,P07437,P17980,P19525,P25788,P25789,Q99436,P31751,P49841,P25787,Q8NEB9,Q9BUF5,P28066,Q00535,P28072,P10398,P49720,P0DP25,P25786,P04350,O43242 40 +Alzheimers disease and mirna effects 0.4159615272065899 2.654246982209915 0.0079485624612702 0.9919982420188244 0.2647651538731004 88 Q99570,P51665,P42345,P36507,P49721,Q9UNM6,P28070,Q13200,P28074,Q15008,Q07866,Q99460,P48556,P48729,Q02750,P20618,Q9BVA1,P62333,O00232,P60900,P07437,P17980,P19525,P25788,P25789,Q99436,P31751,P49841,P25787,Q8NEB9,Q9BUF5,P28066,Q00535,P28072,P10398,P49720,P0DP25,P25786,P04350,O43242 40 +Retinoblastoma gene in cancer 0.4502953159430101 2.5623285934798736 0.0103972895723583 0.9982059685631016 0.282781624217526 51 P00374,P12004,P33981,O00716,P40938,P40937,P15927,P24941,P06493,P16949,P09429,Q00534,Q14527,P33991,Q07864,P52701,P49642,P31350,P35244,P78527,P27694,P26358,P56282,O95067,Q16204,P25205,Q13309,Q9UNN5 28 +Transsulfuration and onecarbon metabolism 0.6329800592691359 2.557135498174926 0.010553809918572 0.9983696935627784 0.282781624217526 18 O43865,P00374 2 +Oxysterols derived from cholesterol 0.7828521558836711 2.5393838135994495 0.0111047923016895 0.9988361025568478 0.282781624217526 8 Q9UBM7,P34913 2 +Cholesterol biosynthesis with skeletal dysplasias 0.878558731267875 2.5169221311598475 0.0118384990260462 0.9992571563020172 0.282781624217526 6 Q15125,Q9UBM7,Q16850 3 +Parkinubiquitin proteasomal system pathway 0.4919542105283765 2.514178296865843 0.011931009833741 0.99929806315265 0.282781624217526 34 P62191,P51665,Q9UNM6,Q13200,Q15008,Q99460,P48556,P62333,Q9BVA1,O00232,P07437,P17980,P62195,O00231,Q9BUF5,P68036,O75832,P04350,O43242 19 +Metapathway biotransformation phase i and ii 0.5957168920043734 2.5062765513868612 0.0122010148504254 0.9994050393253912 0.282781624217526 22 Q86UY6,P28161,P34913,Q16850 4 +Glutathione metabolism 0.8228005536623467 2.4943162081529335 0.0126200063700383 0.9995397269202356 0.282781624217526 7 O75874 1 +Glycogen synthesis and degradation 0.5998317736743195 2.3964293758539736 0.0165556836080367 0.99995892158009 0.3164490200986686 19 P13807,P06737,P30154,P30153,P63151,P36871,P49841,Q14738,P0DP25,P46976 10 +7oxoc and 7betahc pathways 0.7162110482441734 2.334474354024256 0.0195708974212882 0.9999935908938468 0.3164490200986686 9 Q9UBM7,P34913 2 +Pyrimidine metabolism 0.4509079320787256 2.332095968830187 0.0196956430781229 0.9999940657700404 0.3164490200986686 41 Q9H773,Q9NVU0,Q07864,P15531,P11172,P49642,P33316,P04183,P23919,P49643,P22392,Q9NRF8,P17812 13 +Cytoplasmic ribosomal proteins 0.3893079825927265 2.2808551622804165 0.0225570189315107 0.9999989876829322 0.3164490200986686 75 P46778,P46783,P27635,P62917,P18621,P46781,P15880,P62269,P46776,P61247,P61513,P62841,P62847,P23396,P62861,P62241,P84098,P62899,P62906,P39019,P39023,P83731,P83881,P62750,P62081,P05387,P32969,P62753,P62277,P62266,P05388,P08708,P26373 33 +Met in type 1 papillary renal cell carcinoma 0.5421371181417425 2.258010683131912 0.0239449934039364 0.9999995715032308 0.3164490200986686 24 O43815,Q02750,P46109,P31751,Q14241,P36507,Q92733,P10398,Q06124,P46108,Q16512 11 +Cytosine methylation 0.8753235978070133 2.2574714954113957 0.0239786286689218 0.9999995803444376 0.3164490200986686 5 P48735 1 +Fluoropyrimidine activity 0.6282506494660979 2.255133619381389 0.0241249429737224 0.9999996167327244 0.3164490200986686 14 P00374 1 +Vitamin d in inflammatory diseases 0.813649068962092 2.2401576538514294 0.0250806897071411 0.9999997881410048 0.3164490200986686 6 Q16539,P04150 2 +Hepatocyte growth factor receptor signaling 0.6570299531208011 2.23623630824135 0.0253362960390841 0.9999998192201476 0.3164490200986686 12 Q02750,P46109,Q06124,P46108,Q16512 5 +Netrinunc5b signaling pathway 0.5911728845733586 2.1350683676001956 0.0327554260276059 0.9999999982239188 0.3476672411702035 15 Q8TCG1,Q16539,Q02750,P30154,P36507,Q06124 6 +Nrp1triggered signaling pathways in pancreatic cancer 0.6311828861593634 2.097433780967526 0.0359551933247499 0.9999999997607688 0.3714066354249528 12 Q02750,P36507,Q9UIW2,P24941,O14646 5 +Regulatory circuits of the stat3 signaling pathway 0.6665612498787573 2.0852955842297214 0.0370424780132121 0.9999999998791314 0.3714066354249528 9 Q16539,P16949 2 +Thymic stromal lymphopoietin tslp signaling pathway 0.6237155833841423 2.056951508270445 0.0396908905858968 0.9999999999771606 0.372942816510839 12 Q16539,Q02750,P42345,P36507,P62753,Q06124 6 +Mapk cascade 0.6607857937049141 2.055863346596407 0.0397956899879941 0.99999999997862 0.372942816510839 9 Q16539,Q02750,P10398 3 +G1 to s cell cycle control 0.4784741640580583 2.0486279741379496 0.0404985070586683 0.9999999999862716 0.372942816510839 28 Q07864,P56282,Q00534,P49642,P12004,P35244,O43913,P49736,O00716,P42771,Q9UBD5,P15927,P25205,P24941,P49643,Q99640,P33991,P06493 18 +Cellular proteostasis 0.8192982456140505 2.0249870114434585 0.0428686979562704 0.9999999999969256 0.372942816510839 5 Q9UHV9,Q9NQP4,O15212,Q99471 4 +Onecarbon metabolism 0.5666237499862281 1.989445152750973 0.046652090007748 0.99999999999972 0.3742013395825192 15 P00374 1 +Onecarbon metabolism and related pathways 0.573254584346466 1.9399257833782684 0.0523887101013658 0.9999999999999928 0.3961896201415789 14 Q9HBU6,P35790 2 +Dna mismatch repair 0.51636341246729 1.9012742192532104 0.0572661040635322 0.9999999999999996 0.4071893629644637 20 Q07864,P56282,P35251,P52701,Q9UQ84,P12004,P35244,P40938,P40937,P15927,P28340,P18858 12 +Interferon type i signaling pathways 0.512340190475366 1.8746365480449143 0.0608427415833121 1.0 0.4135939175045376 20 Q16539,P23588,P06730,P46109,P42345,P62753,P42224,Q06124,Q53EL6,P46108,Q99873 11 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.6447011522683449 1.8679565140975924 0.0617681325303414 1.0 0.4152191131206283 8 P06730,Q02750,P42345,P36507,Q96KB5 5 +Ethanol effects on histone modifications 0.5679984489856774 1.8267917525016504 0.0677310864126445 1.0 0.4300721194929556 13 P00374 1 +Tcell activation sarscov2 0.5391730292848452 1.8241326583758384 0.0681320192768342 1.0 0.4300721194929556 15 Q02750,O95999,P49841,P36507,P42771,Q9H1B7 6 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.5377571891169142 1.815538995374368 0.0694411189309436 1.0 0.4300721194929556 15 Q02750,O95999,O95433,P49841,Q9UHD1,Q16512 6 +Nucleotide excision repair 0.4709476408859281 1.8095710546707808 0.0703623320283248 1.0 0.4300721194929556 25 P18074,Q07864,P56282,P35251,P41208,P12004,P35244,P54727,P40938,P40937,P15927,P54725,P28340,P27694,P18858 15 +Rac1pak1p38mmp2 pathway 0.5204605666880135 1.7980367348391302 0.0721711866137686 1.0 0.4300721194929556 16 Q16539,P46108,Q16512,P16949 4 +Vegfavegfr2 signaling pathway 0.3141121633105443 1.794014015658456 0.0728109317931455 1.0 0.4300721194929556 185 P48735,O43852,P36507,O15355,Q06124,P15311,Q96J02,Q96B36,P46108,Q16512,Q4G0J3,Q15075,Q16539,P09429,Q01105,Q8WU90,P55209,Q12800,Q02750,P04083,Q8N3C0,Q9Y678,Q16527,P31689,P07737,P06753,Q96KB5,Q96CT7,Q96AQ6,P31948,P62906,P49841,Q14157,Q13177,P04792,Q92783,Q01968,Q00059,P30041,O15371,P00491,P05387,P49591,Q9HCE1,Q96SB4,Q14241,Q01844,Q6ZRI6,Q9UNN5 49 +Physicochemical features and toxicityassociated pathways 0.5050798526683182 1.7914638557197713 0.0732188897649164 1.0 0.4300721194929556 19 Q02750,P07737,P07196,P35080,Q14012,Q16512 6 +Dna replication 0.42620299996206 1.771710178673209 0.0764426791557795 1.0 0.4303322256058901 30 P28340,Q07864,P56282,P35251,P49642,Q7L590,P12004,P35244,O43913,P49736,P40938,P40937,P15927,Q9UBD5,P24941,P25205,P49643,P33991 18 +Nanoparticlemediated activation of receptor signaling 0.6044911959825936 1.7643462867747135 0.0776736954927872 1.0 0.4306701528676791 9 Q16539,Q02750 2 +Cardiac hypertrophic response 0.5563786984623484 1.760220652198854 0.078370401657732 1.0 0.4306701528676791 13 Q16539,Q02750,P31751,P49841,P36507 5 +Dna repair pathways full network 0.3679097498190179 1.7474322901913937 0.0805623804337756 1.0 0.4319361685332948 52 Q9NVI1,Q16658,Q9UQ84,P40938,P40937,P15927,P09429,P27695,Q13535,P13010,P39748,P18074,Q07864,P52701,P41208,P35244,P78527,P18858,P56282,P35251,Q9BXW9,P54727,P54725,P13051,Q9Y620 25 +Serotonin receptor 467 and nr3c signaling 0.7865549934052276 1.7314365556109406 0.0833739314224253 1.0 0.4381443299284988 4 Q02750,P04150 2 +Parkinsons disease pathway 0.6525066435665118 1.704525128802345 0.0882830255481086 1.0 0.4496772917650508 7 Q16539,Q99497 2 +P38 mapk signaling pathway 0.5915531500407651 1.696237050182294 0.0898409965069966 1.0 0.4496772917650508 9 Q16539 1 +Purine metabolism and related disorders 0.5304807569441079 1.6880400235763184 0.0914035462372249 1.0 0.4496772917650508 14 P00491,P31153,P22102,Q06203,P00492,P30520,P07741,P31939,Q9BY32,P60891 10 +Aryl hydrocarbon receptor pathway wp2586 0.5818377359234173 1.6448483141711274 0.1000010958787944 1.0 0.465389715435928 9 Q02750,Q16543,P21359,O00170,P24941,P07900 6 +Reninangiotensinaldosterone system raas 0.8936157980982358 1.6206600955445851 0.1050905561638941 1.0 0.465423302606975 3 Q14012 1 +Il2 signaling pathway 0.5644540670580249 1.608788086286765 0.1076626868288959 1.0 0.465423302606975 10 Q02750,P46109,P36507,P62753,Q06124 5 +Kennedy pathway from sphingolipids 0.7216744866486396 1.6077386470072086 0.1078924305594979 1.0 0.465423302606975 5 P35790 1 +Endoplasmic reticulum stress response in coronavirus infection 0.5746476783376873 1.6066905155697722 0.1081222752079247 1.0 0.465423302606975 9 Q15435 1 +Nucleotide metabolism 0.4877888501559955 1.5913204727175785 0.1115374717080741 1.0 0.4752124674886258 16 P22392,P00374 2 +Tcell receptor tcr signaling pathway 0.4664721212167089 1.567005421783649 0.1171134243196774 1.0 0.4852987788589372 20 Q16539,Q02750,P46109,O95999,Q06124,P46108,Q16512 7 +Insulin signaling in adipocytes diabetic condition 0.743642209880155 1.5514549241521949 0.1207927015992271 1.0 0.4917354041189742 4 P42345,O60343,P31751 3 +Insulin signaling in adipocytes normal condition 0.743642209880155 1.5514549241521949 0.1207927015992271 1.0 0.4917354041189742 4 P42345,O60343,P31751 3 +Follicle stimulating hormone fsh signaling pathway 0.616691183637343 1.5308728264547429 0.1258008262746948 1.0 0.5040364231535784 7 P42345,Q16539,P17612 3 +Biomarkers for pyrimidine metabolism disorders 0.6145743368321788 1.520549017904551 0.1283730489320897 1.0 0.5109585171310153 7 P11172,P31350,P12277,Q9Y606,P23921 5 +Erbb signaling pathway 0.4482341640878234 1.4752059500292165 0.1401571822871439 1.0 0.5334704572674261 21 Q02750,P46109,P31751,P49841,P36507,Q13177,P10398,P46108,Q16512 9 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4381125537908705 1.4750417221723038 0.1402013267859847 1.0 0.5334704572674261 23 Q15125,Q9UBM7,Q16850 3 +Thyroid hormones production and peripheral downstream signaling effects 0.4563609003775877 1.4678762308632565 0.1421378457443303 1.0 0.537458729220749 19 Q16539,O60343,Q02750,P42345,P49841,Q96B36,P17612 7 +Intraflagellar transport proteins binding to dynein 0.6004618294886771 1.451580843363033 0.1466181884925506 1.0 0.54302390552153 7 Q13409,O43237,Q9Y6G9 3 +Nad metabolism sirtuins and aging 0.719879593778228 1.451091847053243 0.1467542864644395 1.0 0.54302390552153 4 P43490 1 +Mirna biogenesis 0.7177729678554136 1.4421771599350472 0.1492524021627819 1.0 0.5446112369373112 4 Q9UPY3,Q9HAV4 2 +Estrogen signaling pathway 0.5891312847306427 1.3960538151885356 0.1626982901659865 1.0 0.5790145032377758 7 Q16539 1 +Interleukin1 il1 structural pathway 0.5093207983891497 1.3614719009729124 0.1733646075036445 1.0 0.592704589975446 11 Q16539,Q02750,P36507 3 +Transsulfuration pathway 0.5811936332115599 1.3570895255287652 0.1747527662320234 1.0 0.592704589975446 7 Q99707,Q9NZL9,P26358,P25325,P17174 5 +Dual hijack model of vif in hiv infection 0.8130295062810409 1.350388133648231 0.1768915151581875 1.0 0.592704589975446 2 Q15370 1 +Cholesterol biosynthesis pathway 0.4969638221914594 1.3476178793517266 0.1777813169681446 1.0 0.592704589975446 12 Q9UBM7,Q13907,Q16850 3 +Leukocyteintrinsic hippo pathway functions 0.5788307242283759 1.3454821818813787 0.1784695715943844 1.0 0.592704589975446 7 Q16539,Q13043 2 +Sarscov2 replication organelle formation 0.8115687992988674 1.3442775199031376 0.1788586621394421 1.0 0.592704589975446 2 Q8NEB9 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.5777335149638163 1.3400912255378936 0.1802156883969226 1.0 0.592704589975446 7 Q16539,P19525,Q13546 3 +Mapk pathway in congenital thyroid cancer 0.8098159509202498 1.336946053715228 0.1812402465214173 1.0 0.592704589975446 2 Q02750 1 +Ethanol metabolism production of ros by cyp2e1 0.8098159509202498 1.336946053715228 0.1812402465214173 1.0 0.592704589975446 2 Q02750 1 +Purine metabolism 0.5214136727455697 1.321520324259967 0.1863279303025664 1.0 0.6028256568612445 9 P00491,P30520,P07741,P31939,Q9BY32,P60891 6 +Neural crest cell migration during development 0.5162662480271991 1.2937766212197972 0.1957425902896528 1.0 0.6108869669726263 9 Q16512,Q99570,P31751 3 +Atr signaling 0.6821914872196775 1.2913769429421336 0.1965730018185671 1.0 0.6108869669726263 4 O60921 1 +Cell cycle 0.3198406049083233 1.2867279378050251 0.1981891318048065 1.0 0.6108869669726263 56 P49736,P61981,O00716,P42771,P33981,P24941,Q99640,P31946,Q00534,P63208,Q13535,Q9UBD5,Q14674,P33991,P49841,O43913,P78527,P63104,Q04917,O95067,P27348,P25205,Q13309,P06493 24 +Nitric oxide metabolism in cystic fibrosis 0.6752826667676206 1.2620825125496191 0.2069190971287171 1.0 0.6136571262885975 4 O60678,Q86X55 2 +Extracellular vesicles in the crosstalk of cardiac cells 0.7991734234369952 1.2528142172579708 0.2102733263367644 1.0 0.6145669682789492 3 P04792 1 +Burn wound healing 0.5041180448320313 1.228257704690337 0.2193502428979201 1.0 0.6271087609870377 9 P07737,Q99439 2 +Immune response to tuberculosis 0.6639657904977194 1.2141227628447693 0.2247008488722075 1.0 0.635252399848998 4 O60244 1 +Egfegfr signaling pathway 0.3181184518206019 1.2045949183675784 0.2283597194096345 1.0 0.6384053996358907 50 Q9UBC2,O14964,P42345,P36507,P30086,P42224,Q06124,Q96J02,P46108,P16949,Q16512,Q16539,Q02750,P46109,P40818,Q92783,P46934,P46940,P41240,P62330,O14965,P11233 22 +Phosphoinositides metabolism 0.4902911022425922 1.2029859142176904 0.22898177143965 1.0 0.6384053996358907 10 Q13614,Q99570,P78356,Q8NEB9,Q01968 5 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.4791760140708501 1.192561151934581 0.2330412878757917 1.0 0.6437898592002465 11 P49841,Q16539,Q13546 3 +Cysteine and methionine catabolism 0.5786058360140434 1.1748647142241742 0.2400488445240343 1.0 0.6571472893078767 6 Q99707,P25325,P48637,P17174 4 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5093917558682454 1.170025221307487 0.2419908192545261 1.0 0.6594794849053528 8 P42345,Q96B36,P49770,P49841 4 +Metabolic reprogramming in colon cancer 0.3337951136112282 1.144794958231768 0.2522941043504811 1.0 0.6757333801144121 35 P48735,Q06203 2 +Microtubule cytoskeleton regulation 0.4067800035007459 1.1345270817645272 0.256573520436929 1.0 0.6757333801144121 19 P46821,Q15691,P49841,Q16555,P17612,P16949,Q16512,Q7Z460 8 +Target of rapamycin tor signaling 0.4585808655997128 1.1282197513587933 0.259227124450355 1.0 0.6757333801144121 12 Q96B36,P62942 2 +Aryl hydrocarbon receptor pathway wp2873 0.6430868167202739 1.125821409888633 0.2602411199448893 1.0 0.6757333801144121 4 O00170,Q16543,P07900 3 +Clear cell renal cell carcinoma pathways 0.32908018124222 1.113869679574159 0.2653350986770242 1.0 0.6771311477375747 36 P60174,P06744,P49327,P53396,P00338,Q96G03,P42345,P36871,P08237,P00558,P07195,P48163,P14618,Q14012,P34896,Q96B36,Q01813 17 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4453922306455626 1.1116486034669075 0.2662892662730765 1.0 0.6771311477375747 13 O75821,O15371,Q14152,P20042,O75822,P55010,P55884 7 +Mirna regulation of prostate cancer signaling pathways 0.4728919637986785 1.1074345007412192 0.2681061163646427 1.0 0.6771311477375747 10 P49841,P36507,Q02750,Q8NCF5 4 +Serotonin receptor 2 and elksrfgata4 signaling 0.7615824865235142 1.1071228026309774 0.2682408380103309 1.0 0.6771311477375747 3 Q02750 1 +Cori cycle 0.4609346949492415 1.0904806292744298 0.2755014815881895 1.0 0.684348310469604 11 P60174,P06744,P00338,P18669,P00558,P37837,Q01813 7 +Thermogenesis 0.3293086944805679 1.0749120712694633 0.2824140969881283 1.0 0.687507338270798 32 O43772 1 +Nocgmppkg mediated neuroprotection 0.5562316270034389 1.0711679016273876 0.284093941434214 1.0 0.687507338270798 6 P98170 1 +B cell receptor signaling pathway 0.368666149051064 1.050065312835727 0.2936880852724624 1.0 0.7022975952167579 25 Q16539,Q02750,P46109,O95999,P49841,O00716,Q06124,P46108 8 +Novel intracellular components of rigilike receptor rlr pathway 0.4508053598030521 1.0339937824975172 0.301139069886148 1.0 0.7073331605986294 11 Q16539 1 +Cardiac progenitor differentiation 0.5895872029629691 1.0302535891584317 0.3028909793915533 1.0 0.7073331605986294 5 Q16539 1 +Autophagy 0.4302016609469938 1.0227391248314337 0.3064312073792679 1.0 0.7073331605986294 13 Q99570,P42345,Q8NEB9,O95352,Q13131,Q96B36,Q9NT62 7 +Methionine de novo and salvage pathway 0.455535727962229 1.0124838127611853 0.3113067825168742 1.0 0.7073331605986294 10 Q9NZL9,Q13126 2 +Hepatitis b infection 0.3462480990033503 1.0056476211733898 0.314585107655134 1.0 0.7073331605986294 28 Q16539,P49327,Q9Y243,Q02750,P31751,P12004,P36507,P42224,P27348,P10398,O15111,Q15750,P51617,P63104,P31946 15 +Kallmann syndrome 0.6144278767112388 1.0053772525374791 0.3147152289903587 1.0 0.7073331605986294 4 Q06124 1 +Exrna mechanism of action and biogenesis 0.6141845824983626 1.0043602712310071 0.3152049922096123 1.0 0.7073331605986294 4 Q9UPY3 1 +Hippoyap signaling pathway 0.6130659632566844 0.9996858349447924 0.3174625692374015 1.0 0.7087263999580367 4 Q13043 1 +Methionine metabolism leading to sulfur amino acids and related disorders 0.6123940368313625 0.9968791742315192 0.3188231614904921 1.0 0.7091471055211315 4 Q99707,P55263,Q9NZL9 3 +Oxidative stress response 0.5369422018065527 0.9822738776178592 0.3259649401502371 1.0 0.7223765157175586 6 Q16539 1 +Energy metabolism 0.4227019973767912 0.9790582618579904 0.3275511929851356 1.0 0.7232425976496607 13 Q16539,Q99873,P49841,Q15648,Q00059 5 +Apoptosis modulation by hsp70 0.6067614249748674 0.9733872308881322 0.3303608827947912 1.0 0.7267939421485408 4 O95831 1 +Vasopressinregulated water reabsorption 0.3829827911247084 0.935738616355782 0.3494077829723756 1.0 0.7522836608479974 17 Q9UJW0,Q13409,Q14203,Q9Y6G9,O43237 5 +Oncostatin m signaling pathway 0.3849337493302358 0.9309710689463192 0.3518685298112869 1.0 0.7539503910348644 16 Q16539,Q02750,P42345,P36507,P62753,Q06124,P24941 7 +Melanoma 0.369267533348683 0.9294145019260572 0.352674315145234 1.0 0.7539503910348644 21 Q00534,Q02750,P0DP25,P36507,O00716,P42771,P10398,Q16512 8 +Tolllike receptor signaling pathway 0.3937690434141385 0.9235378554272546 0.3557269822362969 1.0 0.7567548977712119 15 Q16539,Q02750,P36507,P51617,Q13546 5 +Hijack of ubiquitination by sarscov2 0.591538518154291 0.9102586501587094 0.3626861199290121 1.0 0.7645473956691718 4 Q15370 1 +Pancreatic adenocarcinoma pathway 0.3304838373287139 0.8824456521793882 0.3775358574079805 1.0 0.7782548191117566 28 Q00534,Q02750,P31751,P42345,P36507,Q13177,P30086,O00716,P42771,P10398,P11233,Q16512 12 +Pyrimidine metabolism and related diseases 0.4839285890238964 0.8813076812138404 0.3781513097472828 1.0 0.7782548191117566 7 P23921,P11172,P31350 3 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.4821645353267338 0.8728367765851625 0.3827520509287829 1.0 0.7849660705488599 7 Q16539,Q02750,P36507 3 +Prolactin signaling pathway 0.3503959999341713 0.8503585539541868 0.3951257714636145 1.0 0.7980022353824335 23 Q16539,Q02750,P42345,P49841,P36507,P61981,P62753,Q06124,P63104,Q16512 10 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3716095920952197 0.8469507025818788 0.397022599752252 1.0 0.7980022353824335 16 P04792,P16989 2 +Il1 signaling pathway 0.3989409791149606 0.8421407989141075 0.3997091465881124 1.0 0.798099121075274 13 Q16539,Q06124,Q02750,P36507 4 +Aerobic glycolysis 0.4208255588725723 0.825123538004508 0.4093014576535458 1.0 0.8063750798716416 10 P60174,P06744,P00338,P08237,P00558,P14618 6 +Integrinmediated cell adhesion 0.3197255270861681 0.7997653948246817 0.4238467361969951 1.0 0.8063750798716416 28 P41240,Q9Y243,Q02750,P31751,Q15942,O75116,P36507,Q13177,P18206,Q13464,P10398,P46108,Q16512,P17655 14 +15q112 copy number variation syndrome 0.5627009646302324 0.7925530881386137 0.4280382498137873 1.0 0.8068485194009396 4 Q9BSJ2,Q7L576,Q06787 3 +Initiation of transcription and translation elongation at the hiv1 ltr 0.4354186445242045 0.7889385477911359 0.4301479243031048 1.0 0.8081971869670136 8 P18615,O15379,Q8IXH7,Q8WX92 4 +Cerebral organic acidurias including diseases 0.5316361917968275 0.782599960901991 0.433862064468028 1.0 0.8098926933774684 5 P48735 1 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.4911342244019061 0.7750244611609133 0.4383252055568849 1.0 0.8098926933774684 6 P61201,P04150 2 +Photodynamic therapyinduced ap1 survival signaling 0.4184480299470748 0.7717854682268986 0.4402414999366775 1.0 0.8098926933774684 9 Q16539 1 +Hostpathogen interaction of human coronaviruses autophagy 0.4898002113243129 0.7691088142006038 0.4418287161049818 1.0 0.8098926933774684 6 Q8NEB9,Q9NT62,Q99570 3 +Translation inhibitors in chronically activated pdgfra cells 0.3380066521015836 0.7652275856562957 0.444136035935178 1.0 0.8098926933774684 23 Q16539,P23588,P06730,Q02750,P31751,P42345,Q14240,P36507,P62753,Q04637,Q53EL6,P17612,P60842 13 +Nrf2 pathway 0.3445311407179181 0.7634840459414513 0.4451747734563454 1.0 0.8098926933774684 21 P30041,P00390,P28161,P25685,P48163,P21266,Q14914 7 +Nucleotide excision repair in xeroderma pigmentosum 0.2911897497770336 0.7606701228914352 0.4468541244083091 1.0 0.8098926933774684 34 P18074,Q07864,P56282,P35251,P41208,P12004,P35244,Q86WJ1,P54727,P40938,P40937,P15927,P54725,P28340,P27694,P18858 16 +Exerciseinduced circadian regulation 0.366801347624761 0.760234688808815 0.4471143133687181 1.0 0.8098926933774684 15 Q93062,P25789,Q13907,P21266 4 +Nonsmall cell lung cancer 0.338129524270314 0.7427547955961901 0.4576301481267766 1.0 0.8238555055984652 22 Q00534,Q02750,Q9HC35,P36507,O00716,P42771,P10398,Q13043 8 +Acute viral myocarditis 0.3946574813107419 0.7275386942376398 0.4668960204955892 1.0 0.8311611061175755 11 P49841,Q04637,P42224,P78344,P11940 5 +Micrornas in cardiomyocyte hypertrophy 0.3383349609758547 0.7228605482412245 0.4697655636761093 1.0 0.8311611061175755 21 Q16539,Q02750,P31751,P49841,P36507,Q13144 6 +Vitamin d receptor pathway 0.3679507769361795 0.7155566845786461 0.4742651278163752 1.0 0.8311611061175755 14 P04080,P49427,P42771,Q92783,P30740 5 +Ciliopathies 0.3375680595447586 0.6986456087559074 0.4847735332543865 1.0 0.8381316892157789 20 Q15051,Q15555,Q99570,P36405,Q86Y56,Q01968,O43924 7 +Tgfbeta signaling pathway 0.2768475705525861 0.6783829289183507 0.4975289300864063 1.0 0.850296617803039 39 Q16539,Q02750,P36507,Q13177,O95067,Q96J02,Q9NPI6,Q9Y3F4,Q92905,Q96PU5 10 +Agerage pathway 0.3334213880716942 0.6554241471518275 0.5121947087733869 1.0 0.8589436216724687 19 Q16539,P17931,Q02750,P26038,P15311 5 +Common pathways underlying drug addiction 0.3955275881486648 0.6549468597928363 0.5125019684859473 1.0 0.8589436216724687 9 P36507,Q02750,P10398 3 +Pentose phosphate metabolism 0.4995488156202191 0.6511439156867967 0.5149535901125777 1.0 0.8606268564036174 5 O95336,P37837 2 +Fibrin complement receptor 3 signaling pathway 0.5209003215434231 0.6283764802557071 0.5297573408693546 1.0 0.8706704105145688 4 P51617,O14920,O15111 3 +Apoptosis modulation and signaling 0.333151207367004 0.6249262448321811 0.5320194663476998 1.0 0.8706704105145688 17 P98170,O95817,P42771,Q13546,O95831 5 +Metastatic brain tumor 0.5198107970559029 0.6242306529257816 0.5324761188270917 1.0 0.8706704105145688 4 Q00534 1 +Gastrin signaling pathway 0.2729291944313871 0.6096023158369852 0.5421252771807115 1.0 0.8816822384256194 34 Q16539,Q02750,P49841,P42771,P46108,Q16512 6 +Egfr tyrosine kinase inhibitor resistance 0.3290060983929756 0.6003186556248616 0.5482938880159964 1.0 0.8846386137210193 17 Q02750,P31751,P42345,P49841,P36507,P62753,P10398 7 +Embryonic stem cell pluripotency pathways 0.3306377351387831 0.5980719406790174 0.5497919318332285 1.0 0.8846386137210193 16 Q02750,P31751,P49841,P36507,P10398,Q06124 6 +Tlr4 signaling and tolerance 0.4486385866777133 0.5916886214559381 0.554059117401644 1.0 0.8873680956032916 6 P51617,Q13546,O15111 3 +Airway smooth muscle cell contraction 0.4834958636333701 0.5877164251286913 0.5567226488602939 1.0 0.8873680956032916 5 O75116 1 +Splicing factor nova regulated synaptic proteins 0.3260482961160579 0.5829201473138459 0.5599470570649834 1.0 0.8873680956032916 17 Q9UNS2,Q9NYB0,Q12955,Q9UBB6,Q7Z460 5 +Bladder cancer 0.3808017056196627 0.5822159187503021 0.5604212521670482 1.0 0.8873680956032916 9 P42771,P10398,Q02750 3 +Pilocytic astrocytoma 0.6145528930449888 0.5696213128740794 0.568934569831602 1.0 0.8873680956032916 3 Q06124,P21359 2 +Id signaling pathway 0.6161262050832731 0.5692508068999438 0.5691859457494683 1.0 0.8873680956032916 2 P24941 1 +Congenital generalized lipodystrophy cgl 0.6143733567046566 0.5631175082316968 0.573354870113622 1.0 0.8873680956032916 2 P31751 1 +Serotonin htr1 group and fos pathway 0.3696911153605429 0.5624541853930625 0.5738066099757615 1.0 0.8873680956032916 10 Q16539,Q02750 2 +Osteopontin signaling 0.5029320684250793 0.5610629103170967 0.57475465138847 1.0 0.8873680956032916 4 Q02750,O15111 2 +Type 2 papillary renal cell carcinoma 0.4406366212248652 0.5586178120604308 0.5764225811108985 1.0 0.8873680956032916 6 Q92733 1 +Pdgfrbeta pathway 0.4100323000229559 0.5411570582024556 0.5883993328474353 1.0 0.9012192313232869 7 P19525,Q02750 2 +Disruption of postsynaptic signaling by cnv 0.3801580333625928 0.5225174898540447 0.6013100722176892 1.0 0.9062461212539786 8 Q07157,Q14168,Q7L576,Q12959,P61981,P28482,Q06787 7 +Tolllike receptor signaling related to myd88 0.4922093153946751 0.5220648637157117 0.6016251693940124 1.0 0.9062461212539786 4 P51617,O15111 2 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4302427610412292 0.5165223059987141 0.6054896638573983 1.0 0.9062461212539786 6 Q07157,Q05397,P18206,P12814,P28482 5 +Pi3kakt signaling pathway 0.2501162126502634 0.5091714329326495 0.6106320650216146 1.0 0.9062461212539786 45 P13807,P23588,Q00534,Q02750,P30154,P30153,P08238,P31751,P49841,P63151,Q16543,P36507,Q14738,P24941,Q16512 15 +Folatealcohol and cancer pathway hypotheses 0.5980134385042426 0.5071062563117739 0.6120802654854729 1.0 0.9062461212539786 2 Q99707 1 +Tnfalpha signaling pathway 0.3079367645345443 0.5028296559075089 0.6150840414653334 1.0 0.9062461212539786 19 P06737,Q16543,P63208,Q13200,O00221,Q13546 6 +Mapk signaling pathway 0.2468045083571924 0.4934507332247447 0.6216941426977729 1.0 0.9092030595386 47 Q16539,Q02750,P46109,P31751,P36507,Q16512,P04792,P10398,P51452,Q13043,P46108,P16949,P53041 13 +Il3 signaling pathway 0.3330677657230333 0.4865990929806298 0.6265424664571342 1.0 0.911570309891849 13 Q02750,P46109,Q06124,P17612,P31946 5 +16p112 proximal deletion syndrome 0.275910519181759 0.4838775336400944 0.6284727855146961 1.0 0.9118130341400268 28 P26038,P30153,P17987,Q8TF05,P12004,P78371,P40227,Q9NY27,O15379,P15311,P04075,Q14738,Q16204,P04150,P78318,P49368 16 +Dna irdamage and cellular response via atr 0.253494494196548 0.4726230432765648 0.6364821394460425 1.0 0.91590701394716 37 Q13535,Q9UQ84,O60921 3 +Somatroph axis gh and its relationship to dietary restriction and aging 0.5872042068361206 0.4714069273046921 0.6373501700359576 1.0 0.91590701394716 2 P42345 1 +Spinal cord injury 0.2970501590443027 0.4676086929683184 0.6400644472468904 1.0 0.9162253231778554 21 P17931,P62942,P04083,P27695,P24941,P14174,P06493 7 +Intracellular trafficking proteins involved in cmt neuropathy 0.3284169648018537 0.4636708580449627 0.6428835791492205 1.0 0.9162253231778554 13 P04792,Q13614 2 +Regulation of actin cytoskeleton 0.2427750643851476 0.4477003952602185 0.6543694363721699 1.0 0.9188704154251484 45 P26038,Q99570,P36507,P15311,P46108,Q16512,Q02750,Q9Y281,P07737,Q9UQB8,P78356,Q8NEB9,O75116,Q13177,P18206,P35241,Q8N8S7,P46940,P41240 19 +Glucuronidation 0.4104731120764585 0.4395132562252754 0.6602896788598094 1.0 0.9188704154251484 6 P36871,O60701,Q96G03 3 +Nucleotidebinding oligomerization domain nod pathway 0.3418999898074664 0.4317168500996769 0.6659472192198981 1.0 0.9188704154251484 10 P98170 1 +Praderwilli and angelman syndrome 0.3479733326762844 0.4292079918292096 0.6677718675325897 1.0 0.9188704154251484 9 P42771 1 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.4615609470915068 0.4163420815131235 0.6771597036340864 1.0 0.9188704154251484 4 O14920,O15111,P52564 3 +Cancer immunotherapy by pd1 blockade 0.5631642670549679 0.408894063212836 0.6826174060034997 1.0 0.9188704154251484 3 Q06124 1 +Matrix metalloproteinases 0.5670464504820445 0.4079145051129512 0.6833364432329507 1.0 0.9188704154251484 2 P35613 1 +Ebsteinbarr virus lmp1 signaling 0.4012869260017424 0.4052737269674725 0.6852763164967919 1.0 0.9188704154251484 6 O14920,O15111,P28482,P51617,P07900 5 +Focal adhesion 0.2440020223195574 0.4018983288419318 0.6877588526734129 1.0 0.9188704154251484 37 Q02750,P46109,P98170,P46108,Q16512 5 +Pentose phosphate pathway in senescent cells 0.4327779404645216 0.4017782956260557 0.6878471968369346 1.0 0.9188704154251484 5 O95336,P37837 2 +Sting pathway in kawasakilike disease and covid19 0.5578609000584257 0.3935972045750002 0.6938784454033344 1.0 0.9188704154251484 3 O00221,O15111 2 +Canonical nfkb pathway 0.5578609000584257 0.3935972045750002 0.6938784454033344 1.0 0.9188704154251484 3 O00221,O15111 2 +Epo receptor signaling 0.3735433990867839 0.3914211646521431 0.6954859506261872 1.0 0.9188704154251484 7 P36507,Q02750 2 +Ranklrank signaling pathway 0.2894538888041614 0.3814947929448373 0.7028361342416278 1.0 0.9208045340626164 17 P42345,Q16539,Q02750,P31751 4 +Altered glycosylation of muc1 in tumor microenvironment 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.9208045340626164 2 O15111 1 +Photodynamic therapyinduced nfkb survival signaling 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.9208045340626164 2 O15111 1 +Network map of sarscov2 signaling pathway 0.2556177688540276 0.3790081429582832 0.7046818169768454 1.0 0.9208045340626164 29 Q6PKG0,P06730,P31350,P42345,P62753,P42224,O95067,Q96J02,Q96B36,P51617,P60520,P06493 12 +Ciliary landscape 0.227550895318286 0.3680580052130019 0.7128299832544791 1.0 0.9240784354441778 108 Q9UN37,P51665,Q9UNM6,Q9Y266,P48556,P62333,Q5SW79,Q9H4A3,Q9Y6G9,A0AVF1,O95721,Q7L5N1,O60343,Q9UBW8,O60942,Q15555,Q9UNS2,P07196,Q15051,Q92905 20 +Pdgf pathway 0.3079877665390038 0.3678841758292802 0.7129595999435563 1.0 0.9240784354441778 13 Q16512,Q02750 2 +Hif1a and pparg regulation of glycolysis 0.5432568370249664 0.352902740025149 0.7241613565910359 1.0 0.9240784354441778 3 P00338 1 +Atm signaling in development and disease 0.2679642660377445 0.3501932936240661 0.726193639423413 1.0 0.9240784354441778 24 Q15257,Q14739,P42345,O75150,P04792,Q13535,P06493,Q13263,P78527,P53041,Q00535 11 +Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases 0.540324630974542 0.3449947280403667 0.7300983341195322 1.0 0.9240784354441778 3 O75223 1 +Ras signaling 0.2368206779399531 0.3408588943945263 0.7332098111252447 1.0 0.9241498661057772 33 Q02750,P31751,P0DP25,P36507,Q13177,Q06124,P62330,Q13043,P17612,Q16512,P11233 11 +Allograft rejection 0.3255022797172778 0.3340385347377031 0.7383504805971195 1.0 0.9264984997361254 9 P04439,P08670,Q9BY49,P42224,P19784 5 +Apoptosis 0.2844035854097193 0.3182777525027993 0.7502742584858375 1.0 0.9339833876212588 15 P42771,O00221,P98170 3 +Adipogenesis 0.2747002675257234 0.3030075100637807 0.7618841382897015 1.0 0.9447314764387214 16 P04150 1 +Gaba receptor signaling 0.3493270918665849 0.3025272967778999 0.7622501278975475 1.0 0.9447314764387214 7 Q96CW1,Q9NQX3,P53680,P63010,O94973,O95782 6 +Striated muscle contraction pathway 0.3993530793887994 0.2951859983419031 0.7678517974072172 1.0 0.9447314764387214 5 P67936 1 +Leptininsulin signaling overlap 0.5261466549810229 0.2931828319505855 0.7693824059303331 1.0 0.9447314764387214 2 P40763 1 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.3125061703020032 0.2834221243566354 0.7768532706048312 1.0 0.9467042798056026 9 Q16512,Q13043,Q13177 3 +Genes related to primary cilium development based on crispr 0.2876746344051029 0.2819429222722002 0.7779872768009408 1.0 0.9467042798056026 13 Q9Y496,P36405,A0AVF1,Q6UVJ0 4 +Constitutive androstane receptor pathway 0.3651145333343276 0.2818429091923363 0.7780639672989136 1.0 0.9467042798056026 6 Q08426,Q15257,Q99615 3 +3q29 copy number variation syndrome 0.3054083012851116 0.2802696545726368 0.7792706303193224 1.0 0.9467042798056026 10 O94888 1 +Fragile x syndrome 0.2184292235321746 0.2710739191945723 0.7863341803010544 1.0 0.9514643581642758 48 P46821,P06730,Q02750,P42345,P36507,P42771,Q04637,Q06124,Q9UPY3,Q9Y4R8,P10398,P09497,Q14012,Q96B36,P17612,P51452,P60842 17 +Dna damage response 0.2489713493797215 0.2670204641843096 0.7894534048316058 1.0 0.9525374937340249 25 P49327,Q00534,P35251,Q9BXW9,P11802,O95067,Q13535,P15927,P24941,P06493,P30307,P78527,Q00535 13 +Dna irdouble strand breaks and cellular response via atm 0.239177586829074 0.2638122031197457 0.7919246308705539 1.0 0.9525374937340249 28 Q13535,Q9UQ84 2 +Head and neck squamous cell carcinoma 0.2605125928900376 0.2524513619059365 0.8006922043188309 1.0 0.959245116065134 18 Q9Y243,Q00534,P06730,P62942,P31751,P42345,P11802,P42771,P62753,Q13131 10 +Focal adhesion pi3kaktmtorsignaling pathway 0.2148797751265929 0.2365223845479813 0.813027339603178 1.0 0.9650377061821171 44 P13807,P23588,P08238,Q02750,P30154,Q99570,P30153,P42345,P06730,P31751,Q16543,P36507,P49841,Q9BRX2,P62753,Q14738,Q96B36,P07900 18 +Mirna regulation of dna damage response 0.2396265314399391 0.2356507222883672 0.8137037109257861 1.0 0.9650377061821171 26 P49327,Q00534,P35251,Q9BXW9,P11802,O95067,Q13535,P15927,P24941,P06493,P30307,P78527,Q00535 13 +T cell receptor and costimulatory signaling 0.3463794225085843 0.2261667628739888 0.8210717202508726 1.0 0.9650377061821171 6 P49841 1 +Type i interferon induction and signaling during sarscov2 infection 0.4836451407776082 0.2112550702303045 0.8326882404435756 1.0 0.9650377061821171 3 P19525 1 +Rett syndrome causing genes 0.2525251547274135 0.2093007297155626 0.8342134821622611 1.0 0.9650377061821171 16 P46108,P42858 2 +Amyotrophic lateral sclerosis als 0.2717770597379778 0.2060988566574605 0.8367136918558575 1.0 0.9660530220854844 12 Q16539,P36507,P07196,Q9UER7 4 +Pregnane x receptor pathway 0.3580626103936586 0.186250463839066 0.852248351802323 1.0 0.9713721941235977 5 P62195,Q99615 2 +Pathogenic escherichia coli infection 0.2275712750655447 0.1824040103995355 0.8552656787593429 1.0 0.9713721941235977 26 O15144,O15145,Q9BVA1,P68371,O75116,Q13464,P27348,P15311,Q9BUF5,Q14247,P07437,P63104,P04350 13 +Mesodermal commitment pathway 0.2198446475054011 0.1615515675651957 0.8716589996547375 1.0 0.972977296662576 27 P42858,Q8N3C0,Q16527,Q16204,P17612,Q93063,Q8IWS0 7 +Chromosomal and microsatellite instability in colorectal cancer 0.2333662739740838 0.1586864459388069 0.8739159174333786 1.0 0.9737000553355324 20 P48729,Q02750,P52701,P31751,P49841,P10398 6 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.4612912649722575 0.1565642505697386 0.8755882789234242 1.0 0.9737700528468228 2 P40763 1 +Base excision repair 0.2340846949188647 0.14770145175524 0.8825783858698106 1.0 0.9797429788096064 17 P09429,Q07864,P56282,P12004,P27695,P13051,P18858,P39748 8 +Wnt signaling pathway and pluripotency 0.2242263456020631 0.1208427758383746 0.9038155681305232 1.0 0.9858082553171356 18 P63151,P30153,P30154,P49841,P43034 5 +Il10 antiinflammatory signaling pathway 0.3390466684869965 0.1144052077094905 0.9089165859477626 1.0 0.9858082553171356 4 P53004 1 +15q133 copy number variation syndrome 0.4229714201546797 0.11224193983383 0.9106315760726028 1.0 0.9858082553171356 3 Q9BXW9 1 +Il6 signaling pathway 0.2357495376243081 0.1078519797151977 0.9141131094758892 1.0 0.9858082553171356 12 P49841,Q06124,Q02750 3 +Eukaryotic transcription initiation 0.2179529871102245 0.0892578977233949 0.928876953214542 1.0 0.9912545065230618 15 Q9NVU0 1 +Hedgehog signaling pathway wp4249 0.2658305265323543 0.0839189176375055 0.9331208985149072 1.0 0.9912545065230618 7 Q9Y496,P48729 2 +Hippomerlin signaling dysregulation 0.2070519141763806 0.0821818892844319 0.9345020749813248 1.0 0.9912545065230618 20 Q16512,Q13043,Q13177,Q9Y4B6 4 +Myometrial relaxation and contraction pathways 0.2023698251112369 0.0782183302715298 0.9376543812396796 1.0 0.9912545065230618 22 P61981,Q04917,P27348,Q99439,P17612,P63104,P0DP25,P31946 8 +Insulin signaling 0.1841633414299339 0.0741392233533913 0.9408996054014772 1.0 0.9912545065230618 52 P13807,Q16539,Q02750,Q99570,P31751,P42345,P49841,Q8NEB9,P36507,Q06124,O60343,P46108,P46976 13 +Joubert syndrome 0.2016298195419833 0.0649481731809759 0.9482152648809612 1.0 0.9912545065230618 18 P41208 1 +Type ii interferon signaling ifng 0.2638281573182213 0.0603020207723765 0.9519150925333212 1.0 0.9912545065230618 6 Q06124,P19525 2 +Sars coronavirus and innate immunity 0.3605024832018709 0.0552847366103693 0.9559116219888664 1.0 0.9912545065230618 2 P42224 1 +Wnt signaling pathway 0.2005509021635766 0.0545848595126772 0.956469201133034 1.0 0.9912545065230618 15 P49841,P48729,Q00534 3 +Overview of interferonsmediated signaling pathway 0.3514460999123589 0.0513843042702085 0.9590192916281086 1.0 0.9912545065230618 2 P42224 1 +Mir124 predicted interactions with cell cycle and differentiation 0.3508618171194837 0.0511538549854971 0.9592029220573696 1.0 0.9912545065230618 2 Q13131 1 +Malignant pleural mesothelioma 0.1793521374460204 0.0493146427955015 0.9606685504525758 1.0 0.9912545065230618 69 P42345,P36507,P42771,Q13043,P24941,Q96B36,Q16512,P31946,P09429,Q16539,P23588,P48729,Q02750,Q9Y4R8,P31751,P49841,Q13177,Q04637,Q9HCK8 19 +Iron metabolism in placenta 0.2877592754893292 0.0373819334777471 0.9701804775980878 1.0 0.9943541314035036 2 P21399 1 +Relationship between inflammation cox2 and egfr 0.2437883659748542 0.0318001778191428 0.9746314048302108 1.0 0.9943541314035036 4 Q9Y243,P28482,P31751 3 +Lncrna in canonical wnt signaling and colorectal cancer 0.1793925823466179 0.0255232078354323 0.97963763733964 1.0 0.9968155719879096 15 P48729,Q00534,P49841,Q9HCK8,P19784,Q13363 6 +Ccl18 signaling pathway 0.2035834012831454 0.0204992066275991 0.9836451449637929 1.0 0.9976584856017036 8 P42224,P07196,P00338 3 +Cell migration and invasion through p75ntr 0.2004792784331585 0.0179467544576712 0.985681330346325 1.0 0.9976584856017036 8 Q16512 1 +Endoderm differentiation 0.1519545838947382 0.0063576139162583 0.994927392184533 1.0 1.0 35 P15531,O14981,Q92541,Q8N3C0,Q86VP6,P04150 6 +Wnt signaling 0.1475509132301039 0.0030315617054996 0.997581167425054 1.0 1.0 15 P48729,P49841,O75116,Q9HCK8,P19784 5 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3d9a97702ad3919ee0678b1e33edd4d44477e503 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ABHD16A", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APMAP", "APP", "APRT", "ARAF", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG5", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCKDHA", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "C15orf39", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP3", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNP", "COA1", "COA3", "COASY", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBI", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESCO2", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "FABP5", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FPGS", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F2", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIRA", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMC1", "LAMTOR3", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUZP1", "LYN", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBD3", "MBNL1", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFGE8", "MFN2", "MGA", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NIPBL", "NKRF", "NME1", "NME2", "NME6", "NONO", "NOP2", "NPAT", "NPC1", "NR3C1", "NRP1", "NSD1", "NSDHL", "NSF", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PAX6", "PBK", "PBRM1", "PBXIP1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGT", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2B", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PNKP", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBFOX2", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RBPJ", "RBPMS", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RIF1", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARS", "SASS6", "SBF1", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIPA1", "SIRT1", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPAG1", "SPEN", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SURF1", "SUZ12", "SYNE2", "TAB1", "TAF5", "TAF6", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCF20", "TCP1", "TCTN3", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMED10", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TRRAP", "TSC2", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC21B", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE3A", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UIMC1", "UMPS", "UNG", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP32", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR26", "WDR48", "WDR5", "WDR73", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ACLY", "ACO1", "ACTN1", "ADK", "ADSS", "AHCYL1", "AHSA1", "AIFM1", "AIP", "AKT1S1", "AKT2", "AKT3", "ALDOA", "ANK3", "ANXA1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APRT", "ARAF", "ARF6", "ARL3", "ARPC2", "ARPC3", "ASCC3", "ATG3", "ATG7", "ATIC", "ATR", "AURKA", "BAG3", "BAIAP2", "BCL10", "BLVRA", "BSG", "BTAF1", "C15orf39", "CALM3", "CALU", "CAMK1", "CAND1", "CAPN2", "CARM1", "CCDC124", "CCDC6", "CCNB2", "CCT2", "CCT3", "CCT6A", "CDC25C", "CDC34", "CDC37", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CEP170", "CETN2", "CFL2", "CHD1", "CHD1L", "CHD8", "CHKA", "CHORDC1", "CHUK", "CIP2A", "CKB", "CLASP1", "CLTB", "CLUH", "CNN2", "COPG1", "COPS2", "COPS3", "COPS5", "COPS6", "COPS7A", "CRK", "CRKL", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CTBP1", "CTPS1", "CTPS2", "CTTN", "CYFIP1", "CYP51A1", "DAXX", "DCAF1", "DCP1A", "DCTN1", "DCTN4", "DCTPP1", "DHCR7", "DHFR", "DICER1", "DLG1", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC7", "DNMT1", "DPYSL2", "DTYMK", "DUSP3", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "E2F3", "EBP", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOA", "ELOB", "EML4", "ENAH", "EPHX2", "EPS15L1", "ERCC2", "ESPL1", "ETF1", "ETNK1", "EWSR1", "EXO1", "EXT2", "EZR", "FAF1", "FANCD2", "FANCI", 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"PFN1", "PFN2", "PGAM1", "PGK1", "PGLS", "PGM1", "PGM2", "PHF6", "PIK3C3", "PIK3R4", "PIP4K2B", "PKM", "PKMYT1", "PKN1", "PLXNA1", "PNP", "POLD1", "POLE", "POLE2", "POLR3E", "PPAT", "PPM1G", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PRCC", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKDC", "PRMT1", "PRMT3", "PRPS1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC3", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME2", "PTGR1", "PTK2", "PTPA", "PTPN11", "PUS1", "PYGL", "RAD23A", "RAD23B", "RAD54B", "RALA", "RBPMS", "RDX", "RFC1", "RFC3", "RFC5", "RIPK1", "RNF40", "RNGTT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL13", "RPL17", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL27A", "RPL3", "RPL31", "RPL36A", "RPL37A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPS10", "RPS13", "RPS15", 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b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..acfed34d1f4decbf9b4d6ae50c96279e69ddffb4 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b58f0fe22509c85b2bbe0a7237bfc3194779617dd3d983ba9a5ebdf8e6315bb +size 80407 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..273e203d2676f97524b7957cc5d5ed6f106fb4e4 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +cytoplasmic 240 428 3.350373565132793 0.0008070264234856 124.09466019417476 406.9029126213592 -0.4121717953581456 0.5506942467967898 46.16452501157925 33.3466682410518 1.7222786645379733 0.3786550145352743 1.0 0.104298131904802 0.0002871010863471 2.2501597312647773e-07 3.5402995452923156e-20 +centrosome 21 36 2.8772715089110616 0.0040113029354602 10.383495145631068 33.00242718446602 0.0139063681278158 0.6761540252153022 5.184790997414422 3.5283173376255657 0.7969589118121964 0.3037119526257112 1.0 1.0 0.1421535555390922 0.0260351232348132 0.0182964880418995 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c186c6eca045a797c9da4fcf8f2aaec34a85ec26 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.6470588235294 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..62586b28dcb0a1fc4f29c2e25f1ba179d8c203fb --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..01d576220dfeaae024b0d226f88951d8219b7702 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +cytoplasmic 0.4237189475856707 3.350373565132793 0.0008070264234856 0.0136312299421717 0.0137194491992556 428 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240 +centrosome 0.5304372033368695 2.8772715089110616 0.0040113029354602 0.0660471150848815 0.0340960749514122 36 Q15691,P61981,P33981,Q07866,P31946,P48729,Q5SW79,Q9Y6G9,P17612,Q13442,P00338,P41208,P23258,P63104,O43237,Q04917,Q13409,P27348,P0DP25,Q7Z460,P06493 21 +nucleoplasm 0.3191815519458741 1.0448671725977994 0.2960843637679804 0.9974422952465514 0.5445232003640051 381 Q15691,Q9H2J4,Q7Z6M1,O43592,P49721,P25685,P28070,Q13200,Q9H1E3,Q13043,Q4G0J3,Q16539,Q92973,Q96F86,Q9H4L7,P20618,Q15036,P14324,P31689,Q14012,P14174,O60921,P78356,P41208,Q969U7,Q99615,O95456,O75832,Q9NTZ6,Q99439,Q9H7E9,P98179,P18858,Q00535,P12277,P28072,Q13283,Q9C0E2,P49720,P0DP25,Q9NVU0,Q9BQ61,O15355,P28074,Q14320,P24941,P62826,Q96HR8,Q9H814,P48729,P42356,Q96D46,Q7L590,P60900,Q9UN86,Q96KB5,O75448,P25788,P08238,O15212,P26641,Q99436,P31751,P55060,Q13177,P61289,P28066,O43237,P05455,Q13614,Q9UHY1,O00505,Q01844,O60701,O75190,Q9UN37,P51665,O95433,O60869,O75937,P33981,P42771,Q9HAV4,Q15008,Q99460,Q99640,O60244,P62333,Q16543,P78371,O00232,Q96EK5,P83916,P14618,P17980,P30626,P62195,P25789,P31948,P53396,P52701,P36405,Q2NL82,Q7Z4Q2,Q13907,P78346,P63104,O60684,Q9Y5L0,Q9Y4P1,P52294,P27348,Q6P2P2,P19784,O95747,P25786,P07900,O43242,P06493,Q8IV63,P26038,O14980,Q96GA3,Q9UBE0,P61081,Q9UBQ5,Q9UNM6,P61981,O95429,P31946,Q08945,Q9NWV4,Q9P289,O95373,P00338,P25787,P49841,P53004,O75150,O00231,Q15003,P23258,Q13263,P84085,P78527,Q9UL46,P62258,Q8WXX5,P50995,O15397,Q96EY4,O60884 152 +focal_adhesions 0.5451687235246594 1.0201077651184385 0.3076773544486431 0.998071386794835 0.5445232003640051 6 P41240,Q16512,Q13177 3 +big_aggregates 0.2839206826770534 0.6996044481336365 0.4841743638940596 0.9999870416507418 0.7482694714726376 34 Q92973,Q8IV63,Q9Y5L0,P52294,P51665,Q02952,Q99615,Q96EK5,P62826,Q9NT62,O60684,P30626 12 +cytoskeleton 0.2669620941841333 0.5728590458500685 0.566740136021497 0.9999993320809912 0.8028818593637873 36 O75122,Q7Z460,Q5SW79,P68371,P08670,Q13561,Q13409,Q9UHD8,P12814,Q13043,P27816,Q9Y6G9,Q99439,P52732,P60660,Q15019,P35579,P06493 18 +cell_contact 0.2043970850557937 0.1603127513804425 0.8726347146375595 0.9999999999999992 0.927174384302407 32 Q99961,P48729,P50570,Q15942,P18206,P61981,Q04917,Q14247,Q9UQB8,Q9UKS6,P62258,Q13740 12 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9dc34b370466611205566f418665f56ceae57d0f --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANAPC4", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APC", "ARAF", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BMS1", "BOP1", "BPNT1", "BRD2", "BRD3", "BRD4", "BTF3", "BUB1B", "BYSL", "C1orf123", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP3", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2A", "CDS2", "CEP170", "CETN2", "CHEK2", "CHMP1A", "CHMP4B", "CHMP6", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COMMD2", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CUTC", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP2", "DCTN2", "DDB1", 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"PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK2", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "RER1", "RHOA", "RHOG", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPLP1", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", 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b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71ad0f2a3da0ab36daccbb0cd14d486cbd1c7c2210e6278d6e564e27a49b691c +size 86082 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..34502b3a9764dc61d3a3bc08171cb751e26a1f63 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +protease 17 40 3.368554211205076 0.0007556353546294 10.902912621359222 40.48300970873787 0.4803723668923849 0.5637578889383219 6.152613404953344 2.1366434682897735 1.0933280509795595 0.3608053434874421 1.0 0.003639941270827 0.0254749821013702 3.853690750349182e-06 1.335981197931492e-09 +non-receptor serine/threonine protein kinase 34 66 2.895255893166095 0.0037884955898461 16.135922330097088 52.12621359223301 -0.134221300875087 0.6060262879741318 7.554075018956698 12.250365250469567 0.92962806947858 0.321800658077224 1.0 0.6743340557649219 0.394092206905719 0.3470189493865518 0.1714550593348604 +translation initiation factor 27 46 2.830871250536083 0.0046421403107219 12.444174757281552 44.851941747572816 0.1145008827355917 0.6467304989659429 6.887394567659453 2.159854614961781 0.9002593912782545 0.3253626339773532 1.0 1.0 1.0 0.2037122235382634 0.0002305240226419 +hydrolase 7 23 2.311839595538093 0.0207865244952025 5.730582524271845 22.686893203883496 0.1039794126037792 0.5340059271703876 3.435640815918521 2.8019623945440895 0.9464611702434822 0.3066554522137604 1.0 0.0265864003984115 0.0149914480702132 0.0018945002996002 0.0042820394936164 +isomerase 5 10 2.273659113690176 0.0229864902627852 4.155339805825243 8.842233009708737 -1.0375526110207862 0.3099114619973769 2.1889274828803034 1.3004341560610309 0.9270052824321618 0.2774387033429801 1.0 1.0 0.1265462710440741 0.0442367692127036 2.763867591720716e-05 +kinase 8 22 2.141949451670095 0.0321975498658517 5.342233009708738 19.16990291262136 0.4829035688938301 0.5416328570606787 2.5230708027725983 3.055357699220451 0.834324426685503 0.3184920920789588 1.0 0.0363628425052917 0.0235138787886837 0.019457743384681 0.0035910021710753 +phosphatase 5 17 2.0466143882089773 0.0406959610084991 3.5849514563106797 16.065533980582526 -0.9938490068264416 0.2953388308351354 2.1722134806253504 2.590699657402366 1.0537282297009678 0.2539607611250225 0.0066692820712412 0.0406061543885706 0.1388614812827933 0.0060584295805293 0.0464752879206614 +transmembrane signal receptor 1 5 2.0305227954303677 0.0423034264694854 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 1.0 0.0695355637495909 0.2213471409258044 0.6594980914947266 0.94273816641597 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..63c1983e2bfe07f5ddbf7a3cb3bf885fb2a9b8ae --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 159, + "title": "Average number of proteins per term", + "value": 14.635220125786164 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..436acbf769b0ef53ab48f81e0fa0db4be67a669d --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4c7adf88650b80795c593058a315d36124ef8213 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,60 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +protease 0.5763588133851478 3.368554211205076 0.0007556353546294 0.1132493369134282 0.1201460213860769 40 P25788,P25789,P62333,P20618,Q99436,Q9UNS2,P49721,P28072,Q9UNM6,P28070,P60900,P25786,P28074,P49720,P28066,P48556,O43242 17 +non-receptor serine/threonine protein kinase 0.4468187044236607 2.895255893166095 0.0037884955898461 0.4531139019168891 0.1864449954791767 66 Q8IV63,P42345,P36507,P33981,Q13043,P24941,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q14012,P17612,Q96KB5,P19525,P31751,P49841,O75116,Q13177,P78527,Q13546,Q99986,Q00535,O14874,Q96Q15,Q9UHY1,Q96SB4,P10398,Q9NYV4,O14965,P06493 34 +translation initiation factor 0.4879490290733552 2.830871250536083 0.0046421403107219 0.5227996295320688 0.1864449954791767 46 P51665,Q14232,P20042,P60228,Q9UBQ5,O75822,P63241,Q9Y3F4,P23588,Q9NR50,Q15056,Q9ULC4,Q9UJA5,P46199,O75821,O75153,Q14152,Q7L5N1,Q04637,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884,Q92905 27 +hydrolase 0.5585258603722828 2.311839595538093 0.0207865244952025 0.964559189560122 0.2938750198468617 23 P34913,P15586,Q96C86,Q9BQG2,O60502,O43865,Q9HB07 7 +isomerase 0.6908069333510368 2.273659113690176 0.0229864902627852 0.9752149116327508 0.2938750198468617 10 P06744,P34949,Q8WWH5,Q15125,Q13907 5 +kinase 0.5402073294946544 2.141949451670095 0.0321975498658517 0.9945034770780066 0.2938750198468617 22 P15531,P42356,Q8NEB9,Q9HBU6,Q9NVE7,Q9HA64,P22392,P35790 8 +phosphatase 0.5553703918569489 2.0466143882089773 0.0406959610084991 0.9986477798387584 0.2938750198468617 17 Q9H0R4,Q9H773,Q9NPH0,Q8NCE2,Q9BSD7 5 +transmembrane signal receptor 0.8206172007778163 2.0305227954303673 0.0423034264694854 0.9989642821970492 0.2938750198468617 5 Q99720 1 +phosphatase modulator 0.5940086254481787 1.7680068097781911 0.0770597652294349 0.9999970986569988 0.39524202166065 10 Q5H9R7,Q96C90,Q15435 3 +reductase 0.4180012773435193 1.7040732346962248 0.0883674062468031 0.999999591346497 0.3973625076769018 30 P00374,Q15392,P35270,Q9UBM7,Q9P2T1 5 +tubulin 0.6217076785885784 1.5553138952532628 0.119871329625719 0.999999998476506 0.4485721199526767 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +damaged DNA-binding protein 0.7435512183308532 1.5510714075166008 0.1208845723723222 0.9999999987314768 0.4485721199526767 4 Q9NQE9,P54725 2 +chaperone 0.3273271579726587 1.5351693509638282 0.1247422347240001 0.999999999369595 0.4485721199526767 75 P62942,O95433,Q99543,O75937,P25685,O15260,Q14203,Q00688,P49321,Q13526,Q9UHV9,Q15813,Q16543,Q99471,P31689,P78318,Q96JJ7,Q15814,Q969U7,Q99615,O95456,Q8WXX5,O60884,Q86Y56 24 +non-motor microtubule binding protein 0.4605682263587506 1.5269613839869227 0.1267706140364675 0.9999999995640804 0.4485721199526767 20 P46821,Q9UN37,Q15691,Q15555,O75351,Q8IWC1,O75122,P78559 8 +translation factor 0.6138602057048133 1.5170648901521848 0.1292503015793318 0.9999999997226424 0.4485721199526767 7 P51114,Q53EL6,Q05639 3 +viral or transposable element protein 0.8538019045964106 1.4657356103532184 0.1427203287946157 0.9999999999767468 0.4485721199526767 3 Q9H2J4 1 +nucleotide kinase 0.5053212956634949 1.4638195732451866 0.1432432529586282 0.9999999999788968 0.4485721199526767 13 P00491,Q14558,P04183,Q13126,P23919,P11908,P60891 7 +microtubule or microtubule-binding cytoskeletal protein 0.5224701580237794 1.4349774450746156 0.1512935249700659 0.9999999999952962 0.4485721199526767 11 Q8IWJ2,Q13409,Q9Y266,Q9Y6G9,Q8IVD9,O43237 6 +ubiquitin-protein ligase 0.3178597575338547 1.431296529048298 0.1523452482858147 0.999999999996138 0.4485721199526767 66 Q9GZZ9,O75155,Q93034,O95155,Q9UBE0,P61081,Q5T4S7,Q96J02,Q86UK7,Q8TBC4,P19474,Q16763,P63208,Q96PU5,Q9HB71,P68036,Q15386,Q7Z6Z7,Q9NT62,P46934,Q8TDB6,Q9UII4,Q86VP6,Q9UBT2,Q8IYU2 25 +phospholipase 0.5292593349185722 1.416971241444247 0.1564913357774906 0.999999999998229 0.4524022252476548 10 Q9Y6Y8,Q8IV08,Q8N2A8 3 +GTPase-activating protein 0.4426747781507121 1.375997633205594 0.1688223660245005 0.9999999999998296 0.4549619694558574 19 P21359,Q9NVG8,Q8TC07,Q8N6T3,Q4KMP7,O60343,Q66K14,Q15042,Q0IIM8,P46940 10 +mRNA capping factor 0.8211942384259169 1.338585842810331 0.1807055374636812 0.9999999999999828 0.4782689500942453 3 O60942 1 +primase 0.8060181127665793 1.3210664165536528 0.1864792196869653 0.9999999999999944 0.4782689500942453 2 P49642 1 +serine protease 0.4233968890332296 1.2212707656041948 0.2219835184017369 1.0 0.4971180200827629 18 Q86TI2,Q4J6C6,Q9H3G5 3 +G-protein modulator 0.6130576491272183 1.1325872786334428 0.2573876133633643 1.0 0.5456617403303324 5 P11274,P50395 2 +decarboxylase 0.5607446248740638 1.0920456314431548 0.2748130447706129 1.0 0.5469011957717722 6 P14174,P30046 2 +protein phosphatase 0.4017790472273808 1.0781602112883997 0.2809622649752064 1.0 0.5469011957717722 18 Q9UNI6,P63151,O15355,Q14738,Q06124 5 +pyrophosphatase 0.7490014749078541 1.0587143695584655 0.2897298816461742 1.0 0.5550247130330325 3 Q9UKK9 1 +scaffold/adaptor protein 0.2885357049476905 1.0460441780732983 0.2955406360367492 1.0 0.5594162039267038 89 Q9UNF1,P61981,P46108,Q96CX2,O43823,P31946,Q5VYK3,Q6SZW1,Q96T76,Q96JJ3,Q5SW79,Q02952,Q8WX93,Q8N3C0,Q9H6Z4,Q15036,O60271,O60664,Q9UNH7,Q9UQB8,Q13596,Q4G0X4,P46109,Q92616,Q92783,Q9UBB6,Q9UHD1,Q8N8S7,P63104,P62258,Q9Y5X3,Q96L92,P35613,Q9H9A6,Q04917,P27348,Q9UGP8,Q9NZQ3,O60749 39 +kinase inhibitor 0.742641943121501 1.0343371102527938 0.3009785937723004 1.0 0.5630070165858325 3 Q96P16 1 +carbohydrate kinase 0.5338117337118402 0.9679129583282846 0.3330878420790308 1.0 0.6039386146482579 6 Q01813,P08237,P00558,P51570 4 +basic leucine zipper transcription factor 0.720619820589578 0.9505122232594588 0.3418520460273158 1.0 0.6039386146482579 3 Q7L1Q6 1 +RNA methyltransferase 0.378486020276308 0.8901830760642963 0.3733675905109912 1.0 0.6301377123984567 16 Q8IZ69,Q969Y2,Q9NXH9 3 +metalloprotease 0.3405899857373667 0.8799785329594918 0.3788709389589781 1.0 0.6301377123984567 26 O43847,Q96KP4,Q6P179,Q96E52 4 +non-motor actin binding protein 0.3047392939317996 0.8770481131590185 0.3804605055990682 1.0 0.6301377123984567 34 Q16658,P47755,P60981,Q9Y281,P23528,Q9UEY8,P07737,Q14247,Q15417,P35080,Q14019,Q99439,Q6IBS0,Q13045,P57737 15 +protease inhibitor 0.4275570719583618 0.8610798366296524 0.3891940735656543 1.0 0.6379572958447323 10 P04080,P30740,P30086,P98170 4 +translational protein 0.6918276265667525 0.8427027823300268 0.3993946907184378 1.0 0.6479975084105267 3 O95260 1 +calmodulin-related 0.4100529278046103 0.8099436972842223 0.417972535779735 1.0 0.6629689955172937 11 P41208,P0DP25,O43852 3 +transporter 0.2727067911591941 0.7908614098660541 0.4290248696504068 1.0 0.6629689955172937 57 O43772,O60684,Q9HAV4,Q9C0E2,O14617,Q9HD45,Q00169,Q9H2D1 8 +transferase 0.2918382656068172 0.7073715839653941 0.479335590967954 1.0 0.7258510377514732 31 O43505,P28161,Q06203,P21266,P43490 5 +general transcription factor 0.2889608740913211 0.6066301751891326 0.5440963701219563 1.0 0.7912267343682309 29 O60244,P55199,Q15648,O00716,Q9ULK4,P29083,P23193,P13984,Q15370,O75448 10 +histone modifying enzyme 0.3255330619989249 0.5685188130445095 0.5696827349480795 1.0 0.8160320257364383 16 Q9UBL3 1 +actin or actin-binding cytoskeletal protein 0.2869735888913046 0.4400276411879596 0.6599170877662273 1.0 0.8824873678576064 23 P26038,O15145,Q15942,Q16527,Q96HC4,P15311,Q9UNF0,P35241,Q9UKS6,P60660,Q9UHB6 11 +transcription cofactor 0.3351561852117429 0.4316054425048673 0.6660282021566841 1.0 0.8824873678576064 11 O00625,P51858 2 +G-protein 0.4041009962283158 0.4156503114203991 0.6776659056738161 1.0 0.8853955229430227 6 P84085,Q9NTK5,P62330,P18085 4 +cytoskeletal protein 0.4317186793736701 0.3981805020133902 0.6904971373895272 1.0 0.8853955229430227 5 Q15019 1 +DNA metabolism protein 0.2309286420915744 0.3231948573852904 0.7465476753155009 1.0 0.924065722593988 40 Q9Y248,P33991,O43670,Q9BQ61,Q9NYB0,P54277,P38935,Q15477,O60921 9 +nucleotide phosphatase 0.4194085451714798 0.2880604742370473 0.7733004477679764 1.0 0.928654659775013 4 Q5TFE4 1 +protein-binding activity modulator 0.517073715482294 0.2855950264254852 0.7751883132093322 1.0 0.928654659775013 3 O14737 1 +mutase 0.3437569879966439 0.283492694756239 0.7767991808180927 1.0 0.928654659775013 7 Q96G03,P18669 2 +actin binding motor protein 0.3252176059853109 0.2243644986888482 0.8224736924678988 1.0 0.9615685081058524 7 P67936 1 +zinc finger transcription factor 0.2819374820209694 0.1985372166744483 0.8426247695402458 1.0 0.9666245604049378 10 Q2TAL8 1 +membrane traffic protein 0.2035931262392931 0.1813576865661397 0.8560868293126418 1.0 0.9666245604049378 73 A6NIH7,Q9UBC2,Q9HD26,O60763,Q9UPT5,P40855,Q9NZZ3,O75436,Q96RL7,Q86VS8,Q6NUK4,Q9Y296,Q9NUQ3,O00203,Q9BXS5,O00221,P20645,Q9HD42 18 +tight junction 0.467134092900983 0.1664417379002638 0.8678093299142811 1.0 0.9666245604049378 2 Q9UDY2 1 +methyltransferase 0.2407244760360955 0.150723423503249 0.8801938950362389 1.0 0.9666245604049378 15 Q86TU7,Q9BTV6,Q9HBK9,Q9BV86 4 +chaperonin 0.2479881301390411 0.1061280471821243 0.9154807583714686 1.0 0.9969961683634486 10 P17987,P50991,P78371,P40227,Q99832,P48643,P49368 7 +translation elongation factor 0.2225929055520993 0.0862397887333054 0.931275801674927 1.0 1.0 13 P24534,P29692,P13639,Q8NE71,Q9UG63 5 +major histocompatibility complex protein 0.3345018989190759 0.0456409121365464 0.9635964599629008 1.0 1.0 2 P04439 1 +deaminase 0.2922935239517098 0.0327879886784457 0.9738436567100436 1.0 1.0 3 P08397 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9db947d1a39cc4f704f57794bb136f7d4dfe39da --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "membrane-bound signaling molecule", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "APRT", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATL2", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP31", "BCAS2", "BCKDHA", "BCKDK", "BCLAF1", "BCR", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRD7", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA1", "COA3", "COASY", "COG4", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH7", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERO1A", "ERP29", "ESCO2", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GINS1", "GINS2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACE1", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT3", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMTOR3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED21", "MED23", "MED24", "MED25", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFGE8", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOB4", "MOCS3", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "ND1", "ND5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NF1", "NFKBIE", "NFRKB", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PARG", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RBPJ", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A11", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A1", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYNCRIP", "SYNGR2", "TAB1", "TAF10", "TAF15", "TAF2", "TAF6", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC2L", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTC28", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H4", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF326", "ZNF598", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCF1", "ABCF2", "ACP6", "ADD3", "AHCYL1", "AHSA1", "AKAP12", "AKAP8", "AKT2", "AP1M1", "AP3B1", "AP3D1", "ARAF", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARPC3", "AS3MT", "ASCC3", "ASH2L", "ATE1", "ATG3", "ATR", "AURKA", "B4GAT1", "BAIAP2", "BCKDK", "BCR", "BSG", "BZW1", "CACYBP", "CALM3", "CALU", "CAMK1", "CAND1", "CAND2", "CAPZA2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDC37", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CEP170", "CETN2", "CFL1", "CFL2", "CHKA", "CHMP1A", "CHMP5", "CHORDC1", "CLASP2", "CLUH", "CNDP2", "CNN2", "CNN3", "COPS3", "COPS5", "COPS6", "CORO7", "COTL1", "CPVL", "CRK", "CRKL", "CSNK1A1", "CSRP2", "CSTB", "CTTN", "CUL5", "DCPS", "DCTN1", "DCTPP1", "DDT", "DHCR24", "DHCR7", "DHFR", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DPH7", "DPP9", "DSTN", "DTX3L", "DTYMK", "DUSP12", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "E2F3", "EBP", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4G1", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELL", "ELMO2", "ELOB", "ENAH", "EPHX2", "EPS15L1", "ERAP2", "ETNK1", "EXOC7", "EZR", "FKBP1A", "FKBP3", "FLII", "FN3KRP", "FSCN1", "FXR1", "GALK1", "GCC2", "GCN1", "GDI2", "GINS2", "GMPR2", "GNS", "GOPC", "GPI", "GSK3B", "GSTM2", "GSTM3", "GTF2E1", "GTF2F2", "GTPBP3", "HACE1", "HDGF", "HDHD2", "HERC5", "HINT3", "HLA-A", "HMBS", "HOOK3", "HUS1", "HUWE1", "IDI1", "IGBP1", "IGHMBP2", "IQGAP1", "ITCH", "KCTD12", "KCTD21", "KIAA0368", "KPNA6", "LIMA1", "LRRC40", "M6PR", "MAGED2", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP7D3", "MAPK14", "MAPRE1", "MAPRE2", "MCM4", "MCTS1", "MED1", "MED14", "MED23", "MED24", "MGEA5", "MIF", "MMS19", "MPI", "MSN", "MTAP", "MTIF2", "MTMR14", "MTOR", "MYG1", "MYL6", "NAMPT", "NASP", "NCDN", "NCKIPSD", "NEDD4", "NEDD4L", "NF1", "NFKBIE", "NME1", "NME2", "NRBP1", "NRDC", "NT5DC1", "NTMT1", "NTPCR", "NUDC", "NUDCD3", "NUDT12", "NUDT5", "OLA1", "OMA1", "PACSIN2", "PACSIN3", "PAK2", "PALLD", "PANK4", "PBK", "PDCD4", "PDCD5", "PDCL3", "PDLIM5", "PEBP1", "PEX19", "PFDN2", "PFDN5", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGK1", "PGM2", "PI4KA", "PIK3C3", "PIN1", "PIR", "PITPNA", "PKMYT1", "PKN1", "PLD3", "PLD6", "PLIN3", "PMS1", "PNP", "PPAT", "PPM1G", "PPP1R14B", "PPP1R7", "PPP2R2A", "PPP2R5D", "PPP6R3", "PREPL", "PRIM1", "PRKACA", "PRKDC", "PRPS1", "PRPS2", "PRPSAP1", "PSMA1", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC6", "PSMD13", "PSMD3", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PTPN11", "QRICH1", "RAB3GAP1", "RAD23A", "RANBP3", "RDX", "REEP3", "RIPK1", "RNGTT", "ROCK2", "RPRD1A", "SAE1", "SARM1", "SEC23IP", "SEC63", "SEPT2", "SERPINB1", "SETD3", "SIGMAR1", "SKIV2L", "SKP1", "SLC25A20", "SLC25A32", "SMG1", "SNX1", 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sha256:65acd6804539ae050a8e6d00d103c120ca151a301c6f9d46b341840cabbfb859 +size 133066 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..31ced1c1f03b5400b0e8d9c1fd0c65e23c2db674 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b975e1b4796d325962e5e3e444fdde6a38c34fc86583757f4b041ce98051096 +size 456622 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..952664a4084cfd4adf0c1eb47be2a3bda2696284 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Kinase 63 125 3.304674255744841 0.0009508684493362 29.444174757281555 103.84466019417476 -0.2192751790196224 0.62201990995362 12.072165290634954 17.79740751359367 0.9191239718594064 0.3288870087456925 1.0 0.3534827720731577 0.2610760015746404 0.2957622790482684 0.1028468477383573 +Reductase 2 16 2.5654803407440068 0.0103033059853177 4.563106796116505 16.313106796116504 1.2016212969729014 0.3130807121312539 1.9089462498224232 1.180966799206311 0.8349037556988175 0.2876306629725971 1.0 0.0081256981844374 0.031373049189738 0.0326106125072858 0.1652047572335966 +Phosphatase 15 30 2.506392278708594 0.0121970216648608 7.742718446601942 30.405339805825243 0.0011582111829947 0.5971159611689348 3.9366118678881192 4.536611651098374 0.8836005513113829 0.3054605251584339 1.0 0.4260868249492235 0.6790618821322686 0.3175987790956137 0.5071497141120543 +Phosphatase inhibitor 4 7 2.4173710340528767 0.0156330726941245 2.728155339805826 6.172330097087379 0.9635556310357324 0.3115567860102488 1.3049136024465862 0.9562829575598468 1.0731560672377305 0.3073869469134278 1.0 0.0639684350193291 0.1265462710440741 0.0042425564235442 0.0003706302782608 +Unclassified protein 13 21 2.353617078402442 0.0185917520661569 5.597087378640777 17.512135922330096 -0.1656966122071348 0.6003162490107786 3.470792313525416 2.238747114284973 0.8204432808177233 0.2974448567603577 1.0 0.1801156574188796 0.0614247268920475 0.0185450998789275 0.0008092232876479 +Phosphatase modulator 5 11 2.240559652074661 0.0250546127280943 3.2184466019417477 8.21116504854369 0.7670748435043443 0.3739387538838107 1.5675252632835437 1.2965868569491776 1.0363110244436506 0.3073927580302922 1.0 0.1155957163384056 0.2223047329091382 0.0033507773717699 0.0012863968531589 +Protein phosphatase 6 12 2.110455748763629 0.0348191189005089 4.480582524271845 11.614077669902912 -0.2694804053289399 0.5257620679018572 2.3805668841248058 2.115384211650315 0.9503990836062004 0.3128737735252744 1.0 1.0 1.0 0.6706077438596076 0.6506586407039905 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a9e0721feb7bf15f54b61e3b2a44bc7c3df2bef2 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 2159, + "title": "Average number of proteins per term", + "value": 3.1375636868920798 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..30978e2369c7077f22b694e7db766384ad49f0e7 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6824cae9b87070a8eb400d56efa495c0e198054d --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,77 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Kinase 0.4067058530488392 3.304674255744841 0.0009508684493362 0.8717663940655973 0.0396436605549987 125 Q8IV63,Q99570,O75569,P42345,P08237,P55263,P36507,P04183,P33981,Q13043,P24941,P23919,Q9HA64,P51617,Q99640,P35790,Q16512,P60891,Q16539,P48729,Q00534,P42356,Q02750,Q13572,Q9H4A3,Q9BRR6,Q9HBU6,Q13535,Q9P289,Q14012,P14618,P17612,Q96KB5,P19525,P51570,P15531,P78356,P31751,P49841,Q8NEB9,O75116,Q13177,Q9Y3D8,Q9NVE7,P78527,P22392,Q13546,Q99986,Q00535,O14874,P41240,Q96Q15,P12277,Q9UHY1,O95747,Q96SB4,Q9UJ70,P10398,Q9NYV4,P19784,O14965,P11908,P06493 63 +Reductase 0.647527411754577 2.5654803407440068 0.0103033059853177 0.99999999980543 0.0495430682011156 16 P00374,Q9UBM7 2 +Phosphatase 0.5183388705084482 2.506392278708594 0.0121970216648608 0.9999999999968864 0.0534332811035599 30 Q9H0R4,Q13614,Q9Y217,P30154,P30153,P63151,Q8TF05,P33316,A6NDG6,O15355,Q9NPH0,Q14738,Q01968,Q5TFE4,Q9BY32 15 +Phosphatase inhibitor 0.8055608042328253 2.4173710340528767 0.0156330726941245 0.9999999999999984 0.0613669162665723 7 Q01105,Q92688,Q99733,P39687 4 +Unclassified protein 0.5793588564389391 2.353617078402442 0.0185917520661569 1.0 0.0668791776393977 21 P15531,P12277,O75569,Q9BRR6,Q9UJ70,Q9HBU6,Q9NVE7,Q9Y3D8,Q9HA64,P22392,P11908,P51570,P60891 13 +Phosphatase modulator 0.6711468657127313 2.240559652074661 0.0250546127280943 1.0 0.0783955201158779 11 Q01105,P39687,Q5H9R7,Q99733,Q92688 5 +Protein phosphatase 0.6335915701920392 2.110455748763629 0.0348191189005089 1.0 0.0937337627259336 12 P63151,P30153,P30154,Q8TF05,O15355,Q14738 6 +Translation factor 0.4640798005127718 1.937774997417776 0.0526506794163004 1.0 0.1209285285742474 28 P24534,P20042,P60228,O75822,P78344,P63241,P23588,Q15056,Q53EL6,Q9UJA5,O75153,Q14152,P06730,P29692,Q04637,P62495,O15371,Q9Y262,P55010,P55884 20 +Protein kinase 0.3590594662551418 1.9322915343313027 0.053323532729308 1.0 0.1216661078463783 84 Q8IV63,Q99570,P42345,P36507,P33981,Q13043,P24941,P51617,Q99640,Q16512,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q14012,P17612,Q96KB5,P19525,P31751,P49841,O75116,Q13177,P78527,Q13546,Q99986,Q00535,O14874,P41240,Q96Q15,Q9UHY1,O95747,Q96SB4,P10398,P19784,O14965,P06493 39 +Phospholipase 0.8233057962707179 1.8838554632047095 0.0595845289030241 1.0 0.1293880665767813 4 Q8N2A8 1 +CMGC group 0.515920540009865 1.7695072512192471 0.0768092617605227 1.0 0.153699554621748 16 Q16539,Q00534,P49841,Q96SB4,P06493,P24941,P19784,Q00535 8 +Lipid kinase 0.6802823426591736 1.645255795397442 0.0999170716337305 1.0 0.1848508634594894 6 Q8NEB9,P42356,Q13572 3 +Microtubule family cytoskeletal protein 0.3589736985775735 1.6294526356294032 0.1032172338717285 1.0 0.1891731816036179 50 Q9UN37,Q15691,O75351,Q9Y266,Q12756,Q9BVA1,Q9Y496,Q9Y6G9,P13693,P07437,P78559,P23258,Q8WVJ2,Q9BUF5,Q8IVD9,O43237,P46821,Q15555,Q9BSJ2,Q8IWC1,Q9NQT8,Q13409,P04350 23 +Tubulin 0.6217076785885784 1.5553138952532628 0.119871329625719 1.0 0.2105794960634071 7 P07437,Q9BUF5,Q9BVA1,P04350 4 +Atypical group 0.6161494200568209 1.5282312249847554 0.1264551387097197 1.0 0.2184133155794278 7 O14874,Q96Q15 2 +Translation initiation factor 0.4484125375019127 1.511164993321115 0.1307464189878704 1.0 0.224389124479183 22 O75153,P23588,Q14152,P06730,O15371,P20042,P60228,Q9Y262,Q15056,O75822,Q04637,P55010,Q9UJA5,P55884,P78344,P63241 16 +STE20 family 0.6083298497189493 1.4900613022237983 0.1362081180553573 1.0 0.2306457465737385 7 O95747,Q9P289,Q13043,Q13177 4 +Immune response 0.6389800746846481 1.4551094326593497 0.1456389682182091 1.0 0.2411569830455152 6 Q6AI08,P78318 2 +Cysteine protease 0.3410730183481494 1.4243159091324378 0.1543550442016652 1.0 0.252093249797315 48 Q99497,Q92995,Q9NVG8,Q4KMP7,P61247,Q96K76,Q06210,Q14674,P17812,Q96FW1,Q96RU2,Q06203,P40818,Q13107,O60343,Q01804,Q9Y4P1,Q8TC07,O94966,Q66K14,Q9NRF8,P49915 22 +PIKK family 0.712949429991251 1.4217569048361078 0.1550968341646235 1.0 0.2529109251974487 4 P42345,Q13535,Q96Q15 3 +Kinase activator 0.6786299337820568 1.4200121959020429 0.1556041305120956 1.0 0.2534293118684091 5 O95067 1 +PI3/PI4 kinase family 0.8404043638042586 1.4134969147212204 0.1575096679004337 1.0 0.2560896875511521 3 P42356 1 +Ubiquitin-protein ligase 0.4424068963290522 1.3741967601272085 0.1693806063092031 1.0 0.2684512176833347 19 Q93034,P63208,Q8IYU2,Q9HB71,Q96J02,Q7Z6Z7,P46934,Q8TDB6,Q96PU5 9 +Enzyme modulator 0.276128347405044 1.3646328294810754 0.1723684810366124 1.0 0.2714394971247602 129 Q9UBC2,O95155,P98170,P30086,Q5H9R7,Q9UNM6,Q13200,Q99733,P48556,Q01105,P55209,P39687,Q16543,Q96HP0,Q9H6Z4,Q86VS8,Q96P16,O60271,P30740,Q92688,Q15019,P04080,O95373,Q4G0X4,Q15437,O14737,O15397,Q2TAL8,Q9UNS2,Q9NTK5,O95067,Q15436,O43242 33 +Translation elongation factor 0.6873684956895248 1.3133310081951497 0.1890714341933601 1.0 0.2893020740067077 4 Q53EL6 1 +Metalloprotease 0.3439006149700891 1.293382542257511 0.1958787850449592 1.0 0.2978185189521599 39 Q6P179,P51665,O43847,Q7L5N1,Q96KP4,Q96E52,Q92905 7 +STE group 0.4957582186202589 1.2855058305445668 0.1986155805901981 1.0 0.3002878420827995 11 Q02750,P36507,Q13177,Q9P289,Q13043,O95747 6 +TKL group 0.8059614260666179 1.2792334401047811 0.2008148633641615 1.0 0.3021319094099127 3 P10398,Q13546 2 +Protein arginine methyltransferase 0.6752826667676206 1.2620825125496191 0.2069190971287171 1.0 0.3080237186790446 4 O60678,Q86X55 2 +Non-motor microtubule binding protein 0.4240242247161647 1.2254312898234287 0.2204127636811774 1.0 0.3213245379038375 18 P46821,Q9UN37,Q15691,Q15555,Q8IWC1,P78559 6 +Chaperone 0.3358119109547918 1.1882213961970447 0.2347461962107111 1.0 0.3363085850158762 37 P08238,Q5SW79,Q9UHV9,Q15813,Q15814,P78371,Q99471,P61758,P61981,Q04917,P27348,O00170,P07900,Q14203,P62258,Q99426,P63104,P31946 18 +Kinase modulator 0.420525795679384 1.1795898458657306 0.2381633834490908 1.0 0.3393745012345228 17 Q2TAL8,O95163,Q16543,Q86VS8,O95067,Q92616,Q96P16,O60271,P60983,Q9NQG5 10 +Non-protein kinase 0.3991905012780149 1.108253050313285 0.2677525455824801 1.0 0.3682023859315761 20 P42356,P78356,Q13572,Q8NEB9,P04183,P23919,P14618,P35790 8 +Transcription cofactor 0.4513391666199559 1.0869365106188713 0.2770648693081314 1.0 0.3762157565007898 12 O00625,O60244,Q96T76,Q9NPI6,Q15370 5 +SLC25 family of mitochondrial transporters 0.3828916958020528 1.0793706278461552 0.2804225392554853 1.0 0.3791059876346855 23 O43772 1 +Pyrophosphatase 0.7490014749078541 1.0587143695584655 0.2897298816461742 1.0 0.3895261590715314 3 Q9UKK9 1 +CDK1 subfamily 0.7388255915863311 1.042533947989561 0.2971641947175061 1.0 0.3967702513265898 2 P24941 1 +Kinase inhibitor 0.5430422120175677 1.010315630646851 0.3123440948099745 1.0 0.4096907051608353 6 Q96P16,Q2TAL8 2 +CDK family 0.4678939570185724 0.9544605796561452 0.3398505542226857 1.0 0.4333947705651379 8 Q00534,Q00535,Q9NYV4,P24941,P06493 5 +Protease 0.2587288198847745 0.9490776950905532 0.3425810977492847 1.0 0.4347375541187765 123 Q9BYT8,P34913,P51665,O43847,Q92995,Q96E52,Q9H3G5,Q14674,Q96FW1,Q86TI2,P42785,Q06203,Q7L5N1,Q96KP4,Q9Y6M1,O60343,Q01804,Q6P179,Q8TC07,O94966,Q92905,Q96AE4,P49915 23 +STE7 family 0.7198642853279185 0.94765491069794 0.3433051621843712 1.0 0.4352295039084307 3 Q02750 1 +Other group 0.3585716435375202 0.7970123748672993 0.425443844370827 1.0 0.5024799015298772 18 Q99570,Q9UHY1,Q9H4A3,P33981,O14965,Q96KB5,Q99640 7 +CK1 group 0.5525321081362539 0.7518003152589824 0.4521711524014988 1.0 0.5217731256199016 4 P48729,Q8IV63 2 +Cellular structure 0.2532079579996498 0.7483928865172615 0.4542232119623119 1.0 0.5231998369013633 115 Q16658,Q15691,Q9UGI8,Q9UN37,P26038,P47755,O75351,P15311,Q9Y266,Q12756,Q15417,P60520,Q12792,P57737,Q9BVA1,Q9Y496,Q16527,Q9UNF0,P06753,P07437,P13693,P78559,Q9Y6G9,O15145,P67936,P61163,P23258,Q8WVJ2,Q01518,Q9BUF5,P35241,Q9NZ32,Q99439,Q14019,Q9UKS6,Q8IVD9,O43237,P46821,Q15555,Q9BSJ2,Q8IWC1,Q9NQT8,Q9UEY8,Q13409,Q96HC4,Q14247,Q6IBS0,O75122,Q7Z460,P04350 50 +Extracellular structure 0.45587127162739 0.7481380639226054 0.4543768847568579 1.0 0.5231998369013633 7 Q92791 1 +Protein methyltransferase 0.3915622697014889 0.7111829678027323 0.4769708616676633 1.0 0.5391518797594163 11 Q86X55,O96028 2 +Calcium-binding protein 0.3437412690253965 0.6888776024314488 0.4909002952439012 1.0 0.5511459893039952 17 P41208,P0DP25,O43852 3 +AKT family 0.6441717791411135 0.6704789052708523 0.5025525493844227 1.0 0.5584204601754856 2 P31751 1 +CDK4 subfamily 0.6412503651767631 0.6596814310435364 0.5094582853267284 1.0 0.562784211146036 2 Q00534 1 +Protease inhibitor 0.378813818231703 0.6447037685580399 0.5191191736800183 1.0 0.5689384920314247 11 P04080,P30086,P98170 3 +Intracellular calcium-sensing protein 0.3543000298135084 0.6386776940483544 0.5230326265268128 1.0 0.5708935493788619 14 P41208,P0DP25,O43852 3 +Calmodulin 0.3543000298135084 0.6386776940483544 0.5230326265268128 1.0 0.5708935493788619 14 P41208,P0DP25,O43852 3 +Writer 0.3700339277181889 0.6378386279474594 0.5235787315888938 1.0 0.5711425542965245 12 Q86X55,O96028 2 +Nucleoside kinase 0.6268264172998201 0.6108899841997253 0.5412724159816356 1.0 0.5816859861146596 3 P55263,P04183 2 +ROCK subfamily 0.6216768916155491 0.5888319681378008 0.55597399861123 1.0 0.5903500340957306 2 O75116 1 +Methyltransferase 0.349355934926889 0.569685984252315 0.568890697900426 1.0 0.5982635249717583 13 Q9UBP6,Q9HBK9 2 +Hydrolase 0.2456255600334985 0.5492677335789453 0.5828217272242822 1.0 0.6080370060264533 102 P08397,P30153,P15586,Q96C86,Q8N2A8,A6NDG6,Q9NPH0,O15355,Q969T7,Q9H0R4,P30154,P62333,Q8TF05,Q14738,Q9Y450,Q9Y6Y8,Q5TFE4,O43924,Q05639,Q9H2U2,O43865,Q01968,Q13614,O60841,P63151,P33316,Q9UKK9,Q9NPF4 28 +Extracellular matrix glycoprotein 0.4690190621592973 0.4412121994720478 0.6590593822055832 1.0 0.6769311161664388 4 Q9BXS5 1 +IKK family 0.5576979257960951 0.3799428046764149 0.7039878721454942 1.0 0.7199951757281488 2 O15111 1 +Growth factor 0.4231252280915529 0.3694965611423322 0.7117576359222371 1.0 0.7275969393731581 5 P51858 1 +Nuclease 0.2300359372549114 0.3334443551292479 0.7387988863868289 1.0 0.753812285306788 43 Q9Y248,Q9Y6E2,Q9UQ84,Q9Y2L1,P48634,Q9UPY3,Q7L1Q6 7 +Nucleotidyltransferase 0.2393826657918074 0.328660650297371 0.7424121999443132 1.0 0.7567837297827064 31 O60942,Q5TAX3 2 +Actin family cytoskeletal protein 0.2234203740330247 0.3204814709104797 0.7486033743376583 1.0 0.762734631993867 56 Q16658,Q9UGI8,P26038,P47755,P15311,Q15417,Q12792,P57737,Q16527,Q9UNF0,P06753,O15145,P67936,P61163,Q01518,P35241,Q9NZ32,Q99439,Q14019,Q9UKS6,Q9UEY8,Q96HC4,Q14247,Q6IBS0 24 +DNA helicase 0.3048885043856235 0.3027242503944825 0.7621000152916166 1.0 0.7757538580926923 11 Q9H4L7,P46063,P25205,P13010,P33991 5 +Actin binding motor protein 0.3252176059853109 0.2243644986888482 0.8224736924678988 1.0 0.836420490832875 7 P67936 1 +TK group 0.3692982456140335 0.2131592840952171 0.8312027249969631 1.0 0.8448995683938058 5 P41240,Q05397,P07948,Q13308 4 +VRK family 0.4842362036217679 0.2124501069588313 0.8317558981361155 1.0 0.8450639925062933 3 Q8IV63 1 +Histone deacetylase 0.3800058462437896 0.1902840280549132 0.8490865687629687 1.0 0.8613711668445648 4 O15379,Q92769,Q96EB6 3 +ABCC subfamily 0.4799883143441578 0.1898813116354695 0.8494021371987395 1.0 0.8613711668445648 2 O15439 1 +Dehydratase 0.4301995075265911 0.1215930327176786 0.9032213316308536 1.0 0.9138026499489283 3 P61457 1 +Chaperonin 0.2479881301390411 0.1061280471821243 0.9154807583714686 1.0 0.925338463166667 10 P17987,P50991,P78371,P40227,Q99832,P48643,P49368 7 +DMPK family 0.3994739918176413 0.0861783828256017 0.9313246147735456 1.0 0.9404723308213682 3 Q13464,O75116 2 +AMPK subfamily 0.4052001168565673 0.0854361025817486 0.9319146923667224 1.0 0.9406282472275616 2 Q13131 1 +HDAC class I 0.3798947983635261 0.0692052379288047 0.9448262538420622 1.0 0.9527696786758582 3 O15379,Q92769 2 +Lysine-specific demethylase 0.3356704645048168 0.0459784738558777 0.9633274071356056 1.0 0.9691630344854488 2 Q8NB78 1 +Non-motor actin binding protein 0.1722239400839614 0.0398311062440699 0.9682277767057376 1.0 0.973186112619966 30 Q16658,P52907,P47755,Q9UEY8,Q96HC4,Q14247,Q15417,Q14019,Q99439,Q6IBS0,Q12792,P57737 12 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..00e3179e09b87ee41b0f938d3b4236d9d605b052 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-Ketosteroid receptors", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "ATR subfamily", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-CoA-binding protein", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Alpha-tocopherol transfer protein-like", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Aurora kinase b", "Autophagy protein 5", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BTB/POZ domain-containing protein KCTD21", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 3", "Beta-arrestin-1", "Beta-arrestin-2", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline dehydrogenase, mitochondrial", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 6", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydroorotate dehydrogenase (quinone), mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Disks large homolog 1", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity mitogen-activated protein kinase kinase 6", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HACE1", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Ephrin-B1", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAK family", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Focal adhesion kinase 1", "Folate transporter 1", "Folylpolyglutamate synthase, mitochondrial", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucocorticoid receptor", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase 3", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "IRAK family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of growth protein 5", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Interleukin-1 receptor-associated kinase 1", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF13B", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Low density lipoprotein receptor adapter protein 1", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific demethylase 5B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 3", "MAPK family", "MARK subfamily", "MAX gene-associated protein", "MBT domain", "MBT domain-containing protein 1", "MCU family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MSN subfamily", "MST subfamily", "MTSS1-like protein", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Map/microtubule affinity-regulating kinase 3", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Membrane-bound signaling molecule", "Metalloendopeptidase OMA1, mitochondrial", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase kinase kinase 4", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 5", "Myotubularin-related protein 6", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin p54", "Nucleoside diphosphate kinase 6", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase catalytic subunit type 3", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FRG1", "Protein HIRA", "Protein Hook homolog 3", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein NDRG1", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RAF family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA binding protein fox-1 homolog 2", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with multiple splicing", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Rac-gamma serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoblastoma-associated protein", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE11 family", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 12", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase a-raf", "Serine/threonine-protein kinase atr", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek1", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 2", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialate O-acetylesterase", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signal-induced proliferation-associated protein 1", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 1", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 1", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tetratricopeptide repeat protein 28", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor E2F3", "Transcription initiation factor TFIID subunit 10", "Transcription initiation factor TFIID subunit 2", "Transcription initiation factor TFIID subunit 6", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone C", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 13", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 30", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 38", "Ubiquitin carboxyl-terminal hydrolase 4", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 292", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "ARAF", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GALT3", "BAG6", "BAIAP2", "BAK1", "BCAP31", "BCAS2", "BCKDK", "BCLAF1", "BCR", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP170", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COASY", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC4", "ERH", "ERI1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EZR", "FAHD1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GINS2", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACE1", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT3", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HPRT1", "HSD17B10", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5B", "KHDRBS1", "KHSRP", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLRAP1", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LTN1", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARK3", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "MED25", "METTL1", "METTL14", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MOCS3", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTSS1L", "MUT", "MVK", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NF1", "NFRKB", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NR3C1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2B", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSPC1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RB1", "RBBP6", "RBFOX2", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "SAE1", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIAE", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAB1", "TAF10", "TAF15", "TAF2", "TAF6", "TAF9B", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTC28", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP28", "USP30", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF281", "ZNF292", "ZNF598", "ZW10", "ZYX"], "leading_proteins": ["ABCC4", "ACP6", "ACTR10", "ACTR1A", "ADD3", "ADK", "ADPGK", "AHCYL1", "AIP", "AK6", "AKT2", "ANP32A", "ANP32B", "AP1M1", "ARAF", "ARPC3", "AS3MT", "ATG4B", "ATR", "AURKA", "BCKDK", "BZW1", "BZW2", "CACYBP", "CALM3", "CALU", "CAMK1", "CAP1", "CAPZA1", "CAPZA2", "CARM1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDC37", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CEP170", "CETN2", "CHKA", "CHUK", "CKB", "CLASP1", "CLASP2", "CLUH", "CNDP2", "CNN2", "CNN3", "COPS3", "COPS5", "COPS6", "CORO7", "COTL1", "CPVL", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CTPS1", "CTPS2", "CTTN", "CUL5", "DCP1A", "DCPS", "DCTN1", "DHCR7", "DHFR", "DICER1", "DIS3", "DOCK6", "DPP9", "DTX3L", "DTYMK", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "EEF1A2", "EEF1B2", "EEF1D", "EIF2AK2", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOB", "ELP1", "EPHX2", "EPS15L1", "ERAP2", "ESPL1", "ETF1", "ETNK1", "EXO1", "EZR", "FN3KRP", "FSCN1", "FUBP1", "GABARAPL2", "GALK1", "GCN1", "GFPT1", "GINS2", "GMFB", "GMPS", "GNS", "GSK3B", "HACE1", "HBS1L", "HDAC2", "HDAC3", "HDGF", "HDHD2", "HEATR6", "HMBS", "HOOK3", "HSP90AA1", "HSP90AB1", "HUWE1", "IGBP1", "IGF2BP2", "IPO7", "IPO8", "IRAK1", "ITCH", "ITPA", "ITPK1", "KCTD21", "KDM1B", "KIF13B", "KIF1A", "KIF3A", "LYN", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP7D3", "MAPK14", "MAPRE1", "MAPRE2", "MCM3", "MCM4", "MED14", "METTL1", "MMS19", "MSN", "MTMR2", "MTMR6", "MTOR", "NAGK", "NAP1L1", "NAP1L4", "NEDD4", "NEDD4L", "NLN", "NME1", "NME2", "NRBP1", "NRDC", "NSD2", "NT5C3B", "NT5DC1", "NUDC", "NUDCD2", "NUDCD3", "NUDT5", "OCRL", "OLA1", "OMA1", "OSGEP", "OTUB1", "OTUD4", "OXSR1", "P3H4", "PACSIN2", "PACSIN3", "PAK2", "PANK4", "PARK7", "PBK", "PCBD1", "PDCD4", "PDCD5", "PDE6D", "PDLIM5", "PEBP1", "PFDN2", "PFDN5", "PFKM", "PGP", "PI4KA", "PIK3C3", "PIK3R4", "PIP4K2B", "PIR", "PKM", "PKMYT1", "PKN1", "PLD6", "PPA2", "PPAT", "PPM1G", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PRCP", "PRKAA1", "PRKACA", "PRKDC", "PRKRA", "PRMT3", "PRPS1", "PRPS2", "PRRC2A", "PSMC6", "PSMD13", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PTK2", "PTK7", "QRICH1", "RANBP3", "RDX", "RECQL", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPRD1A", "RPRD1B", "RPS3A", "SEC23A", "SEC23B", "SEC23IP", "SEPT2", "SERPINB1", "SET", "SIRT1", "SKP1", "SLC25A20", "SMARCAD1", "SMG1", "SPAG9", "SRPK1", "STK26", "STK4", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCC", "TBCE", "TCP1", "TES", "TK1", "TPM3", "TPM4", "TPT1", "TRMT6", "TTK", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TWF1", "TWF2", "UBE4B", "USP13", "USP19", "USP28", "USP4", "USP47", "USP8", "VBP1", "VPS4A", "VPS4B", "VRK1", "VRK3", "WNK1", "XIAP", "XRCC5", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZCCHC11"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2c9a89814544d67cab453c74790749979179bf3 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3baea41d7c5ce90d6cd0ddecf1805da1ada928c4 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f38441e09b5c26ab2dbc3cffbd10e02d3e752acb7360a587ad03f641fa7bdd9 +size 193830 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c4c8ea0916980a7727ada1e41a5e12e075ffc500 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..cf03cc6f78af3729562760f61f7b36a477285c08 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:455946134048eb76f50ce2a9605a6a6dbcd792a0d3eda6b4dbf264aabedf8ba3 +size 136046 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2da75898c4140a49e203e7c4027e9cf688111f57 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81e9c1a14bc96cb607dc8b3d6a0825c96afe3233c73ab03b1f0ad58b468fe78c +size 123282 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a3c876180a6f993289ef5a3110d151ba10eedeca --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88e563cf70c5aaace0602a4f79e93777e27862d64a6a5665ec4989b0582f1abe +size 76271 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..41f57e32a84f7a70fca5f39997a89b65792515ae --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tclin 11 92 2.912229595643867 0.0035885875605077 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 1.0 0.0005296609958597 0.0011950334974559 0.0072477140307717 0.0103757994921068 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eb39927200b89d4abb49bf4af8dedc4985bab769 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 856.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1f279efa6fd0c52ffc8793d949030b4038729c00 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5c245da984ca3de31f21efe28e3de4fc9bc30eb8 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.4340724030847616 2.912229595643867 0.0035885875605077 0.0142772671668704 0.0143543502420309 92 P48735,P00374,P62942,P20618,Q99720,P49721,Q06203,P04150,P0DP25,O75306,P03886 11 +Tbio 0.1598646354677743 1.4350579248979487 0.1512705919618231 0.4811079676848062 0.3025411839236462 2630 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545 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9f1e19b6047c29ad634db3594d40a18e3b7996ab --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf52", "C2CD5", "C2orf49", "C3orf58", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPI", "CENPV", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COASY", "COG3", "COG4", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM210B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT3", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF2", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM167A", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UIMC1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDHD1", "WDR1", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR7", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAGAB", "ABRACL", "ABRAXAS2", "ACBD3", "ACP6", "ACTR10", "ADO", "AHSA1", "AIFM1", "AK6", "AKAP8", "ANK3", "ANP32A", "ANP32B", "ANXA1", "AP1M1", "AP3B1", "AP3D1", "AP3S1", "API5", "ARFGAP1", "AS3MT", "ASCC3", "ASH2L", "ATE1", "ATG3", 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+One-carbon metabolism 2 11 2.244569878360108 0.0247957582784978 2.6310679611650487 9.946601941747574 0.1844848590355362 0.5629384825857486 2.1609521960097893 0.4204287072266918 0.8637427229562549 0.2980093584487905 1.0 0.0771453392642774 0.0113213926532688 0.0075105395483816 0.0468003866103798 +Immunity 30 81 2.088297741208139 0.0367709850954287 17.820388349514563 76.64077669902913 0.3712215805873788 0.6852303500560589 6.509274327939261 7.523560880911209 0.7685662507868273 0.3361567579513101 1.0 0.3020472621774097 0.6620998983592059 0.1174896031262479 0.0365135539465448 +DNA damage 43 138 2.0121327240099163 0.0442059479382417 41.12864077669903 127.05825242718448 -0.6938464492957 0.4882890211875025 16.06118323444372 16.763098192865755 1.1751325519677638 0.3556003198422716 1.0 0.247280230080337 0.1401315800405851 0.1814307345121119 0.246255858210387 +Sterol biosynthesis 3 16 2.007084505472297 0.044740665762684 4.970873786407767 15.854368932038836 1.2489526119817105 0.2730082640054638 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b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 172, + "title": "Average number of proteins per term", + "value": 32.366279069767444 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d62378296197bb3a45238745bc154ea5840f7359 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5846de7cea8266a257b47ed35867884815588525 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,60 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +One-carbon metabolism 0.6719161972330348 2.244569878360108 0.0247957582784978 0.9866819685270112 0.183207089294358 11 O43865,P00374 2 +Glyoxylate bypass 0.9985392930178209 2.1203319487810792 0.0339780611679716 0.9973832501633612 0.2164528341070786 2 P48735 1 +Immunity 0.3724319415418012 2.088297741208139 0.0367709850954287 0.9984096831511896 0.2180899805659912 81 Q9NVU0,Q13325,P17931,Q9UQ84,Q96J02,O43823,P51617,P09429,Q6SZW1,P04083,Q9Y3Z3,Q9NUD5,Q9UN86,P13010,P14174,Q96RS6,Q13740,P17812,Q96FW1,Q8TDB6,Q01804,Q9Y5A9,O15347,Q6P179,O95999,Q8IV08,Q9UII4,Q13283,Q13309,P25786 30 +DNA damage 0.2988916017402455 2.0121327240099163 0.0442059479382417 0.9995805659798512 0.2204028756374977 138 Q9NVI1,Q96FZ2,Q99497,Q99504,Q9UQ84,O95251,Q9H1I8,P15927,Q9H1E3,P24941,P53041,P09429,Q96K76,Q9H4L7,Q96T76,Q08945,Q7L590,Q9NVH2,Q9Y3Z3,Q8N3C0,Q15004,Q13535,Q9NWV8,Q9UNS1,P23396,O60921,P39748,Q07864,Q96FW1,P41208,P54277,P35244,Q96RU2,Q9NZJ0,Q7Z6Z7,P18858,Q8TDB6,Q96Q15,P54727,Q9P287,P13051,P54725,Q9Y620 43 +Sterol biosynthesis 0.5540800804055253 2.007084505472297 0.044740665762684 0.9996190553407666 0.2204028756374977 16 Q15125,Q9UBM7,Q16850 3 +Cholesterol biosynthesis 0.5540800804055253 2.007084505472297 0.044740665762684 0.9996190553407666 0.2204028756374977 16 Q15125,Q9UBM7,Q16850 3 +Tricarboxylic acid cycle 0.5271704716480088 1.9725187115789864 0.0485504224021946 0.9998084184180704 0.2204028756374977 20 P48735 1 +Ubl conjugation pathway 0.3017610418949603 1.9597117415799985 0.0500294920041366 0.9998533975889952 0.2204028756374977 147 Q9GZZ9,Q15018,Q93034,O75155,O95155,P98170,Q9UBE0,P61081,Q92995,Q5W0B1,Q5T4S7,Q96J02,Q15370,Q9BSL1,Q8TBC4,Q8N806,P19474,Q96K76,Q14527,Q16763,P63208,Q9NWV8,Q96PU5,Q4G0X4,Q96FW1,Q96RU2,Q93008,Q13107,Q9C0C9,Q9HB71,P40818,P68036,Q15386,Q9NZJ0,Q7Z6Z7,P46934,Q9NT62,Q8TDB6,Q96GG9,Q01804,P49427,Q9Y4P1,Q9NXF7,Q9UII4,P54727,Q96DY7,Q9Y4B6,Q86VP6,Q86X83,Q13309,O95260,O94966,Q9Y314,Q9UBT2,Q8IYU2 55 +Nucleotide metabolism 0.6229929675577203 1.8610535954822376 0.0627366084347276 0.9999855387930328 0.2464594234842418 9 O43598,P15531,P33316,Q969T7,P22392 5 +Meiosis 0.5301755981436795 1.8588545384090471 0.0630477594959688 0.9999863415286157 0.2464594234842418 16 Q9UQ84 1 +Adaptive immunity 0.5221297597276239 1.8085088453662792 0.0705273413968807 0.9999965588905916 0.2527229733388227 16 P09429,P04083,Q6P179,Q96FW1 4 +DNA repair 0.3186818470761174 1.7786342072277204 0.0752997521182281 0.9999985803949474 0.2590311472867048 118 Q9NVI1,Q99497,Q99504,Q9UQ84,O95251,Q9H1I8,P15927,Q9H1E3,P24941,P53041,P09429,Q96K76,Q9H4L7,Q96T76,Q08945,Q9Y5B9,Q9Y3Z3,Q8N3C0,Q15004,P27695,Q13535,Q9NWV8,Q9UNS1,P13010,P23396,P39748,Q07864,P52701,Q96FW1,P41208,P54277,P35244,Q96RU2,Q7Z6Z7,P18858,Q8TDB6,Q96Q15,Q9BXW9,P54727,Q9P287,P13051,P54725,Q9Y620 43 +DNA replication 0.3621037460211984 1.714551848592586 0.0864274233339537 0.9999998230684068 0.26726563248908 54 Q9Y248,P12004,P49736,O95251,P40938,P40937,P15927,P49321,P49643,Q08945,Q7L590,Q9Y5B9,Q9Y3Z3,Q9BRX5,Q9UBD5,P33991,P39748,Q07864,P49642,P31350,P35244,O43913,Q04837,Q9NZJ0,P28340,P27694,P18858,Q9UFC0,P56282,P35251,Q9BRT9,P25205 32 +Glycogen biosynthesis 0.7323603734604025 1.654056985581151 0.0981159347632429 0.9999999806837524 0.2909644961944447 5 P13807,P46976,P31751 3 +Nucleotide biosynthesis 0.6732263922163719 1.6129233272245358 0.1067611664901706 0.9999999963150936 0.3112359429882941 6 P11908,Q14558,P23919,P60891 4 +Inflammatory response 0.5406037163852638 1.5359720767973606 0.1245452289174715 0.9999999998840692 0.3511767110459853 11 P09429,Q8IV08,P04083,P14174,Q13546 5 +Phospholipid metabolism 0.4722716706478932 1.517305223098297 0.1291896401151251 0.9999999999535638 0.3527082238063734 17 P35790,Q9NPH0 2 +Differentiation 0.3151871834661975 1.4983042894081011 0.13405421014739 0.9999999999822824 0.3602706897711107 104 Q9Y6E2,Q96A49,Q9HCE5,P51114,O60869,Q8N2A8,P16949,Q6NYC1,Q4G0J3,Q86YR5,P61247,Q6SZW1,P85037,Q00534,Q15645,Q9BXJ9,Q16527,Q96EK5,Q14012,Q16555,A1X283,Q15019,Q96PU5,P15531,P49841,Q6DKJ4,Q7Z6Z7,Q99598,Q9Y5A9,Q96SB4,P43034,O60879,Q96EK7 33 +Glycogen metabolism 0.6002417219177779 1.4505033710006685 0.1469181998326569 0.99999999999865 0.3836300442427824 7 P49841,P06737,P31751 3 +Isoprene biosynthesis 0.8366929593923501 1.4494681903705369 0.1472068774419979 0.999999999998726 0.3836300442427824 2 Q13907 1 +Protein biosynthesis 0.3163989499910449 1.4288336818022482 0.1530520422390888 0.9999999999996098 0.387131636251813 94 P54577,P24534,P49589,Q14232,P20042,P60228,P13639,Q9UBQ5,P23381,O75822,P78344,P63241,Q9HA77,P23588,Q6PKG0,Q9NR50,Q14240,Q15056,Q9ULC4,Q9Y450,P46199,Q05639,O75821,Q14152,P06730,P26641,O43432,P26639,P29692,P26640,Q04637,P60842,P62495,O15371,P49770,O60841,Q9Y285,Q9BTE6,P49591,Q9Y262,P55010,Q13144,P55884,Q9NSD9,A2RTX5,O43776 46 +Purine salvage 0.6644148607949765 1.3577304060562263 0.1745492449032493 0.9999999999999952 0.4228516918782941 5 P00491,P07741,Q13126 3 +Innate immunity 0.3156037841108915 1.3288618422420682 0.1838935547607243 0.9999999999999992 0.4274282624168187 62 Q9NVU0,P17931,Q13325,Q96J02,O43823,P51617,P09429,Q6SZW1,P04083,Q9Y3Z3,Q9NUD5,P13010,Q9UN86,P14174,Q8TDB6,Q01804,Q9Y5A9,O15347,O95999,Q9UII4,Q13283,Q13309 22 +Steroid biosynthesis 0.4111215842181372 1.2483973261105392 0.2118855877469221 1.0 0.4572747055204892 22 Q15125,Q9UBM7,Q16850 3 +DNA condensation 0.5523698069046035 1.2153584299654676 0.2242294155851227 1.0 0.4572747055204892 7 Q15021,P42695,Q15003,Q9BPX3,O95347,Q9NTJ3 6 +Pyrimidine biosynthesis 0.5808233706576624 1.185161975321034 0.2359534109886434 1.0 0.4585736190036276 6 Q9NRF8,P17812 2 +Spermatogenesis 0.3683701038431469 1.1810299713669434 0.2375908171794667 1.0 0.4585736190036276 28 Q99598,Q9HCE5,Q15645,Q8N2A8,Q15019,Q4G0J3 6 +Purine biosynthesis 0.4847475573490973 1.1725206014564176 0.2409881058706748 1.0 0.4585736190036276 10 P22102,Q06203,P30520,P22234,P31939,P49915 6 +Oogenesis 0.5604103811125174 1.090498555325605 0.2754935893489678 1.0 0.5089666023237507 6 Q15645,Q9Y5A9,O60879 3 +Chromosome partition 0.3947162796527821 1.0778173514641538 0.2811152745392808 1.0 0.5089666023237507 20 O43670,P30153,Q96SB4,Q6P1K2,Q14674,P04150 6 +Steroid metabolism 0.359783565496907 1.066263120613854 0.2863047157304401 1.0 0.5098167867960844 27 Q15125,Q9UBM7,Q16850 3 +Sterol metabolism 0.3630116810745727 1.0479913038238262 0.2946426134882001 1.0 0.5098167867960844 26 Q15125,Q9UBM7,Q16850 3 +Cholesterol metabolism 0.3630116810745727 1.0479913038238262 0.2946426134882001 1.0 0.5098167867960844 26 Q15125,Q9UBM7,Q16850 3 +Cell division 0.2551559527562411 0.9679489795258128 0.3330698510894729 1.0 0.5616471998763661 162 Q15018,Q15691,Q9UN37,O43768,O75351,O75400,Q9H6D7,Q6NUK4,Q9Y266,Q14203,P24941,P62826,O75794,Q96CS2,P48729,Q00534,Q9HC35,Q16763,Q9HBM1,Q9NWV8,Q9P258,Q9UNS1,Q9Y6G9,P23396,Q96CT7,Q15019,P53990,O43670,P41208,P36405,Q8NEB9,Q93008,Q9BPX3,P04150,P18858,Q00535,Q9HD42,Q99986,P11233,Q9Y5A9,Q6DKK2,Q15555,P42695,Q9BXS6,O95067,P43034,Q6P1K2,P62330,O75122,O14965,Q7Z460,O94927 52 +Cell shape 0.5262255193818628 0.9332062768782003 0.350713474500341 1.0 0.5850624605766 6 Q96AC1 1 +Lipid biosynthesis 0.2812264249356026 0.871142439374185 0.3836763841150579 1.0 0.6110401672943514 56 Q16850,Q9HBU6,Q15125,Q9UBM7,Q96G23,P35790 6 +tRNA processing 0.2979822127903096 0.8265397655524345 0.4084979701590472 1.0 0.6387422806123283 35 O95163,Q96SZ6,Q7Z4G4,Q9NXH9,Q9Y606,Q9Y3C4,Q9NX74,Q9UBP6,Q9UJA5,Q96PZ0,Q9H9T3,Q99575,P78346,Q9NPF4,Q969Y2 15 +Antiviral defense 0.3169428736699727 0.7786170762132607 0.4362053169467206 1.0 0.6698867367396066 28 Q9NVU0,Q13325,Q14258,Q9UII4,Q9Y3Z3,Q7Z7L1,Q9NUD5,P42224,Q13309,Q96J02,Q9NUQ8,P19525,Q8TDB6 13 +Phagocytosis 0.5358082432037514 0.6858498584902465 0.4928077919649689 1.0 0.72162928933354 4 Q14185,Q96JJ3,P50570 3 +Viral RNA replication 0.6281040023371439 0.6117964876625681 0.5406724138547285 1.0 0.7685591337439116 2 Q15365 1 +Phospholipid biosynthesis 0.3284401325627126 0.585299384006079 0.5583464289861533 1.0 0.7744805305291804 16 P35790 1 +RNA-mediated gene silencing 0.3201238848735001 0.5743787458358323 0.5657115323728545 1.0 0.7784190685450479 19 Q9HCE1,Q5TAX3,Q9UPY3 3 +Mitosis 0.2273353012062787 0.4918747583640346 0.6228078833630486 1.0 0.8240227379880335 123 Q15018,Q15691,O43768,Q9H6D7,Q9Y266,Q14203,P62826,P24941,Q96CS2,P48729,Q9HC35,Q9HBM1,Q9NWV8,Q9P258,Q9UNS1,Q9Y6G9,P23396,Q15019,O43670,P41208,Q9BPX3,P04150,Q9Y5A9,Q15555,P42695,O95067,P43034,Q6P1K2,O75122,O14965,Q7Z460,O94927 32 +Wnt signaling pathway 0.2708504082501533 0.450533026628256 0.6523261457423488 1.0 0.8564892905930076 28 Q92541,P98170,P49841,Q6DKJ4,Q96AC1,Q9HCK8,Q9GZS3 7 +Neurogenesis 0.2335227844230832 0.4008252195641963 0.6885488097028272 1.0 0.8904540997660622 55 Q6SZW1,Q9Y6E2,P15531,P55209,Q9BVA1,P49841,O43379,Q96EK5,Q14012,Q9P265,Q9H9T3,P16949,P46934,Q86YR5,Q00535 15 +Glycolysis 0.2879281671332797 0.3661009211522605 0.7142897701812387 1.0 0.896772558183745 16 P60174,P06744,P18669,P08237,Q9BRR6,P00558,P14618,Q01813 8 +Myogenesis 0.3857883472972934 0.3500248931332594 0.7263200159142269 1.0 0.9052684256322248 6 P51114 1 +Glutathione biosynthesis 0.5201636469900547 0.293139824122595 0.7694152778573242 1.0 0.9520822143270486 3 P48507,P48637 2 +Cilium biogenesis/degradation 0.2484583728560366 0.2518643608498729 0.8011459076184335 1.0 0.9704020852842996 24 A6NIH7,Q15051,Q86Y56,O14965,Q6IBS0,Q01968,O95721 7 +Autophagy 0.2192546430782049 0.2376869344117642 0.8121239181296953 1.0 0.976820377051102 36 P09429,Q8NEB9,Q92995,Q9NT62,Q9NQ88,Q13137,O95721 7 +ER-Golgi transport 0.2073368622098658 0.1979953861200686 0.8430486736166467 1.0 0.993180629192214 52 P35606,P24390,O60763,P48444,Q9Y282,P53621,Q9NR31,Q15437,P61923,O43617,Q9Y678,Q92734,Q8IUR0,Q8N6T3,Q9Y296,O95486,O95487,Q15436 18 +Cell cycle 0.2358526176765308 0.1581681834302743 0.8743242740759574 1.0 1.0 238 Q15018,Q9NVI1,Q15691,Q9UN37,Q8TCY9,O43768,O75351,O75400,Q8WW12,Q9H6D7,O00716,Q6NUK4,Q9Y266,Q14203,P24941,P62826,P49321,Q13526,Q99640,O75794,Q96CS2,P19474,P48729,Q00534,Q9HC35,Q16763,Q9HBM1,Q9NUQ3,Q9NWV8,Q9P258,Q9UNS1,Q14012,Q9Y6G9,P23396,Q96CT7,Q15019,P33991,Q86Y37,P53990,O43670,P41208,P36405,Q8NEB9,Q92733,Q93008,Q9BPX3,P40818,P04150,P61289,P18858,Q00535,Q9HD42,Q99986,P49427,Q9Y5A9,Q6DKK2,Q15555,Q9BXW9,P11233,Q9UPP1,Q96DY7,Q9P287,Q9BXS6,O95067,P43034,Q6P1K2,P62330,P25205,P42695,P19784,O75122,O14965,Q6UVJ0,Q7Z460,O94927,Q8IYU2 76 +Apoptosis 0.1955642881591016 0.1545134924490994 0.8772048735361131 1.0 1.0 126 P98170,Q9H2J4,Q13043,Q96J02,Q16539,Q96JJ3,Q53EL6,Q9Y2J2,P23396,P42858,P31751,Q13177,O95817,O14737,Q9BZZ5,O75832,P04150,P61289,Q13546,O95831,Q00535,O95999,Q9NQ88,Q9UHR5,Q9UNN5 25 +Serine biosynthesis 0.4504820333041269 0.1395610016957898 0.8890068551246524 1.0 1.0 2 Q9Y617 1 +Amino-acid biosynthesis 0.2648346837124101 0.1315958503168535 0.8953039679481063 1.0 1.0 9 P17174 1 +Hearing 0.387087350277536 0.0707935561246074 0.9435620604261876 1.0 1.0 2 O60610 1 +Translation regulation 0.1714104824154388 0.0331466291632621 0.9735576584657584 1.0 1.0 48 Q6PKG0,A5YKK6,P06730,Q9UQ80,P31751,O43432,P27635,Q9BRX2,Q9BPZ3,Q92615,Q04637,P14618,Q92616,Q9Y6M1,P78344,Q9Y450,P61221,P23396 18 +Prostaglandin metabolism 0.2535513585155349 0.0288032924030012 0.9770214750128976 1.0 1.0 3 Q14914 1 +Fertilization 0.2326125073056746 0.027918455760083 0.9777271886124744 1.0 1.0 3 Q99497,Q08431 2 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0317f5032c74af9b511d33ca1e60c8edb51f19c1 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMC10", "ARMT1", "ARRB1", "ARRB2", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM1", "BAG3", "BAG6", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CBL", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "COASY", "COG3", "COG5", "COG7", "COG8", "COMMD2", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC4", "EMG1", "EML4", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESCO2", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM210B", "FAM50A", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPR2", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPHN", "GPI", "GPR89B", "GPSM1", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GYG1", "GYS1", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HIP1", "HIRA", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "ING5", "INPPL1", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRAK1", "IRF2BP1", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD21", "KCTD5", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMC1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDLR", "LDLRAP1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1S", "MAP2K6", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MESD", "METTL1", "METTL14", "METTL3", "MFGE8", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPP5", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUL1", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NACC1", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NELFCD", "NELFE", "NES", "NFRKB", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NME6", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPAT", "NPC1", "NPLOC4", "NPM1", "NR3C1", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "PPAT", "PPCDC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK2", "PTK7", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN3", "RMND5A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERAC1", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORBS3", "SORT1", "SPAG1", "SPATA5", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TAF10", "TAF2", "TAF5", "TAF6", "TAF9B", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLK2", "TLN1", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM14C", "TMEM214", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPRKB", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC28", "TTC4", "TTF2", "TTLL12", "TTPAL", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "UIMC1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDR33", "WDR36", "WDR41", "WDR43", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR75", "WIPI2", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H13", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMAT2", "ZMYM2", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARSD1", "ABCE1", "ABCF3", "ABRAXAS2", "ACP6", "ADPGK", "ADSS", "AHCYL1", "AIFM1", "AKAP8", "AKT2", "ALCAM", "ANXA1", "APEX1", "API5", "APRT", "ARCN1", "ARF6", "ARFGAP1", "ARL3", "ASCC2", "ASCC3", "ATE1", "ATG3", "ATG4B", "ATIC", "ATR", "AURKA", "BABAM1", "BAG3", "BCCIP", "BCL10", "BZW2", "CACUL1", "CACYBP", "CALCOCO2", "CAMK1", "CAND1", "CAND2", "CARS", "CARS2", "CCDC124", "CCNB2", "CDC123", "CDC34", "CDK2", "CDK5", "CDK5RAP1", "CDK6", "CERS2", "CETN2", "CHD8", "CHKA", "CHMP1A", "CLASP1", "CLASP2", "CNOT1", "COMMD2", "COPA", "COPB2", "COPG1", "COPZ1", "CSNK1A1", "CSNK2A2", "CSRP2", "CTPS1", "CTPS2", "CUL5", "CYP51A1", "DCAF1", "DCAF16", "DCTN1", "DCUN1D1", "DHCR7", "DHFR", "DIAPH1", "DIAPH2", "DICER1", "DIP2B", "DNAAF5", "DNM2", "DNPH1", "DOCK1", "DPYSL2", "DTL", "DTX3L", "DTYMK", "DUS2", "DUT", "DYNC1LI1", "E2F3", "EBP", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3J", "EIF3K", "EIF3L", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELMO2", "ELOB", "ELP1", "ELP3", "EML4", "ENSA", "EPB41L3", "ERAP2", "ERGIC3", "ESPL1", "ETF1", "ETNK1", "EXO1", "EYA3", "FAF1", "FAM120B", "FANCD2", "FANCI", "FARSA", "FARSB", "FEN1", "FERMT2", "FOXK1", "FXR1", "G3BP1", "G3BP2", "GART", "GCLM", "GCN1", "GINS2", "GINS3", "GINS4", "GMPS", "GOT1", "GPI", "GPSM1", "GSK3B", "GSS", "GTPBP3", "GYG1", "GYS1", "HACE1", "HAUS1", "HAUS4", "HAUS5", "HBS1L", "HERC5", "HLTF", "HMCES", "HMGB1", "HMGB3", "HTT", "HUS1", "HUWE1", "IDH2", "IDI1", "IFIT5", "IGF2BP2", "INTS7", "IQCB1", "IRAK1", "IST1", "ITCH", "JMJD6", "KAT7", "KCTD21", "KDELR1", "KIFBP", "LARP1", "LARP4B", "LARP7", "LGALS3", "LIG1", "LRWD1", "MAPK14", "MAPRE1", "MAPRE2", "MCM10", "MCM2", "MCM3", "MCM4", "MCTS1", "METTL1", "METTL14", "MFGE8", "MIF", "MMS19", "MOV10", "MSH6", "MTAP", "MTBP", "MTIF2", "NAA15", "NAP1L1", "NARS", "NASP", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NEDD4", "NEDD4L", "NME1", "NME2", "NOSIP", "NR3C1", "NT5C3B", "NUCKS1", "NUDC", "NUDCD1", "NUSAP1", "NXN", "OCRL", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "PA2G4", "PAFAH1B1", "PAICS", "PAIP2", "PAK2", "PARK7", "PCBP1", "PCLAF", "PCNA", "PCNP", "PDCD4", "PDCD5", "PDCL3", "PELO", "PFKM", "PFKP", "PGAM1", "PGK1", "PHF8", "PIK3C3", "PIN1", "PKM", "PKMYT1", "PLD3", "PLD6", "PMF1", "PMS1", "PNP", "POLD1", "POLE", "POLE2", "POLR3E", "POP1", "PPAT", "PPP2R1A", "PPP5C", "PRCC", "PRIM1", "PRIM2", "PRPF40A", "PRPS1", "PRPS2", "PRPSAP1", "PSAT1", "PSMA1", "PSMD10", "PSME3", "PTGR1", "PUS1", "PUS7", "PYGL", "RAD23A", "RAD23B", "RAD54B", "RALA", "RAN", "RCC2", "REEP3", "RFC1", "RFC3", "RFC5", "RIPK1", "RNF219", "RPA1", "RPA2", "RPA3", "RPL10", "RPP30", "RPS3", "RPS3A", "RRM2", "RTF1", "SAE1", "SAMHD1", "SAP30BP", "SAR1A", "SARM1", "SARS", "SASS6", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEPT2", "SH3PXD2B", "SKP1", "SKP2", "SLFN11", "SMARCAD1", "SMC2", "SMC4", "SMG1", "SNAP29", "SPC25", "SRPK1", "SSBP1", "SSRP1", "STAT1", "STK4", "STMN1", "SUPT16H", "SYAP1", "TARS", "TARSL2", "TFG", "TIGAR", "TIMELESS", "TPI1", 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https://git-lfs.github.com/spec/v1 +oid sha256:587a48b3db4e00d1b6ba19f16e94a3b6074c653ad22db1979cccd4cc0ffe73b6 +size 87073 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..68e63f760ae63a64dd0d1d45f5992f75fabaa22b --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +FDA approved drug targets 13 127 3.226793932520708 0.0012518558092151 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 1.0 7.258701529937447e-05 0.000145068056653 0.015715172052959 0.2178921442474439 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d5cc7fcae9eb33a47141677450f7a340db52d62e --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 122, + "title": "Average number of proteins per term", + "value": 22.401639344262296 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b9ae23cf55cd870b9e3e4c0cd906071dd61bc70d --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6fc3832d7e88141bb7be6cf56aacad26cb02a25c --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FDA approved drug targets 0.3963724909397798 3.226793932520708 0.0012518558092151 0.1417175898574049 0.0576197477006925 127 P48735,P00374,P62942,P20618,O75874,Q99720,Q16850,P98170,P04083,P49721,P20645,P04150,P03886 13 +Diamond-Blackfan anemia 0.5468257726587307 1.870470842240065 0.0614184623656233 0.9995618882761944 0.3746526204303023 15 P62847,P39019,P62081,P08708 4 +Amyotrophic lateral sclerosis 0.5242307921434838 1.5742427402179895 0.1154313418306578 0.9999996828616274 0.4856077139082847 13 P07737,Q99720 2 +Cushing syndrome 0.7231304953508089 1.464844070762516 0.1429634648954598 0.9999999933024032 0.5766278876151982 4 O00170,P40818 2 +Diabetes mellitus 0.5037157818672519 1.3861771533017282 0.1656928159770649 0.9999999997477856 0.5933514054523353 12 P13807,O60343,P03886 3 +Hermansky-Pudlak syndrome 0.829631794272359 1.3714851684644067 0.1702237638592765 0.99999999987021 0.5933514054523353 3 O00203,O14617 2 +Albinism 0.829631794272359 1.3714851684644067 0.1702237638592765 0.99999999987021 0.5933514054523353 3 O00203,O14617 2 +Glycogen storage disease 0.5213724330616603 1.321298113963265 0.1864019826101428 0.9999999999882508 0.6176360572769032 9 P06737,P00338,P36871,P35573,P46976 5 +Microphthalmia 0.5733528410357553 1.3185611966386233 0.1873158534364378 0.9999999999897564 0.6176360572769032 7 P41227,O15347 2 +Proto-oncogene 0.3153467196076904 1.167722253651531 0.2429188173464087 0.9999999999999982 0.7280374788413767 49 P49915,Q01105,P55199,Q01844,P31751,Q92733,Q13107,Q9H6U6,Q16204,P10398,O14965,O96028,P06753,P46108,Q96GG9 15 +Alzheimer disease 0.5731519345360604 1.1495503927246835 0.2503291000393854 0.9999999999999994 0.7280374788413767 6 P49841,P03886 2 +Palmoplantar keratoderma 0.4543522932111811 0.8849376488121361 0.3761902609555823 1.0 0.8602757162573974 8 Q9H4L7,Q6PD74 2 +Ectodermal dysplasia 0.445175878510296 0.8382072018585479 0.4019143429784737 1.0 0.8602757162573974 8 Q02750,Q9H4L7 2 +Nemaline myopathy 0.6879929886064953 0.8381755852543935 0.4019320969399316 1.0 0.8602757162573974 2 P06753 1 +Gout 0.6406660823838846 0.6575285200708825 0.5108411388686436 1.0 0.9032263614778916 2 P60891 1 +Hereditary nonpolyposis colorectal cancer 0.6141111558657444 0.5681542517978275 0.569930232329839 1.0 0.9502906875837044 3 P54277 1 +Hereditary hemolytic anemia 0.3381489699994505 0.5506639783805896 0.5818640421450474 1.0 0.9502906875837044 14 P60174,P06744,P00390,Q15437,P00558,P04075,Q8NB49 7 +Autism 0.4381193612989442 0.5483302376703248 0.5834651685559171 1.0 0.9502906875837044 6 O14874,P27635,Q9HCK8 3 +Ichthyosis 0.3719318603016853 0.5395064805818108 0.5895374265320641 1.0 0.9502906875837044 9 Q15125 1 +Bardet-Biedl syndrome 0.6059012562080128 0.53382674724455 0.5934614065407493 1.0 0.9502906875837044 2 Q9BW83 1 +Ciliopathy 0.3256472172925614 0.5247260713055807 0.5997736306880757 1.0 0.9502906875837044 15 Q01968,O43924,Q15051 3 +Autism spectrum disorder 0.273714313926085 0.2487565536344044 0.8035490999934296 1.0 0.999054091881197 14 O14874,P06730,P27635,Q12955,Q9HCK8,Q05639 6 +Primary microcephaly 0.2341163762143233 0.120028728468047 0.9044603904426456 1.0 0.999054091881197 14 P35606,Q00534,P42695,O43379,Q6UVJ0 5 +Joubert syndrome 0.3206385307928496 0.0889723788742772 0.9291038615071188 1.0 0.999054091881197 4 O43924 1 +Systemic lupus erythematosus 0.3747303220208576 0.0653897916848221 0.947863651740992 1.0 0.999054091881197 3 P05455 1 +Cockayne syndrome 0.311805961426069 0.0367268172010069 0.9707028260291956 1.0 0.999054091881197 3 P18074,P19447 2 +Xeroderma pigmentosum 0.311805961426069 0.0367268172010069 0.9707028260291956 1.0 0.999054091881197 3 P18074,P19447 2 +Zellweger syndrome 0.2531423560362392 0.0353604735839775 0.971792302497772 1.0 0.999054091881197 4 P40855,O75381,P50542 3 +Peroxisome biogenesis disorder 0.2531423560362392 0.0353604735839775 0.971792302497772 1.0 0.999054091881197 4 P40855,O75381,P50542 3 +Premature ovarian failure 0.2869629154015224 0.0319810187686641 0.974487187982479 1.0 0.999054091881197 3 O60879 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9af437e5e0a4eb863b47a35258484dd1efbd8d69 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hyperlipidemia", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pseudohermaphroditism", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD11", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOL2", "APP", "APRT", "ARAF", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ASAH1", "ASCC1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG5", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATR", "ATRX", "ATXN10", "ATXN2", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCKDHA", "BCKDK", "BCL10", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRD4", "BRD7", "BRI3BP", "BUB1B", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCNB2", "CCT5", "CDC16", "CDC20", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBI", "DBN1", "DBT", "DCAF8", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "E2F3", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHHADH", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC9", "EXT2", "EXTL3", "EZR", "FABP5", "FAF1", "FAH", "FAM120A", "FAM210B", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GRB2", "GSDME", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H4C1*", "HACE1", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HOXD11", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2R", "IGHMBP2", "IKBKB", "ILF3", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS12", "INTS8", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KCTD21", "KDM1A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KTN1", "L2HGDH", "LACTB", "LAMC1", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPPRC", "LSS", "LTA4H", "LYN", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K4", "MAP4", "MAPK1", "MAPK14", "MARK3", "MARS", "MARS2", "MATR3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED23", "MED25", "MESD", "METTL14", "MFGE8", "MFN2", "MFSD8", "MGA", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCOS", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MVK", "MYH10", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NACC1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "ND5", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK1", "NEK9", "NF1", "NFKBIE", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NR3C1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUS1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OMA1", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PANX1", "PARK7", "PARN", "PARP1", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDXK", "PEPD", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PIP4K2B", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PTDSS1", "PTK2", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RABL3", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD54B", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RSPRY1", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SBDS", "SBF1", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", 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+Kinase 66 127 3.074133979711155 0.0021111459900402 30.50485436893204 106.71601941747574 -0.2641293583388165 0.6049298455860649 12.51203210149689 18.652531405798065 0.9470946250413178 0.3363863519769051 1.0 0.3704096562018247 0.282517950507413 0.3315771707061437 0.1816463788646831 +Initiation factor 31 37 2.686950125803314 0.0072107718606497 12.29126213592233 35.407766990291265 -0.0821190079233033 0.5969551913028055 6.190159851695042 1.941808251479095 1.0044409846809916 0.334601111447651 1.0 1.0 1.0 0.0909853548684221 0.018870184963526 +tRNA-binding 7 19 2.4897400712530007 0.0127836549818904 6.949029126213592 16.92233009708738 -0.3264059317165362 0.5738257209306772 3.635694673158518 1.6630730730715708 0.8614230541250553 0.3143694632770396 1.0 1.0 0.2223047329091382 0.0033507773717699 0.000181120869522 +Chaperone 31 102 2.326369703090231 0.019998836447687 26.29126213592233 101.00970873786407 -0.1006528897629623 0.7348972204864018 10.338570508275588 7.048714191952073 0.7343008134465656 0.3053244065975439 1.0 0.1922254295262415 0.0243497840139476 0.0009466637314448 7.320078712372353e-07 +Calmodulin-binding 8 35 2.125775796292923 0.0335219322618236 10.03640776699029 32.779126213592235 -0.2520849335110281 0.5917094116392749 4.609101876241264 4.7589722327647035 0.8426461576025018 0.3077880283609658 1.0 1.0 0.2213471409258044 0.1855085217645392 0.0345136819195897 +Serine/threonine-protein kinase 40 73 2.099269363917124 0.0357931624571097 18.424757281553397 58.6747572815534 -0.2386691929507323 0.5877823066168736 8.485376838226976 12.595500957030788 0.9438037227041202 0.3256457489861977 1.0 0.7468347616085298 0.767611242266147 0.7035849091895494 0.5354518797107619 +Protein phosphatase 7 19 1.963328117325652 0.0496080603520396 7.473300970873787 18.633495145631063 -0.8305266992827439 0.4057679448538682 3.254088656918621 3.4074653076432 1.1089521586479685 0.3309480708044852 1.0 1.0 0.2248900268904883 0.3950228281530177 0.8373003312717844 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..25ec144fe5341ce3506948826d02e732f6f314ed --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 41.896907216494846 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..45e3f092e5cc5e684469cc11a47933e0c3c8c649 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1feaa30987cae524ab8c4ab3b6565536fb95dae5 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,37 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Kinase 0.3862169799748303 3.074133979711155 0.0021111459900402 0.185350750601059 0.029254451576272 127 Q99570,P42345,P08237,P55263,P36507,P04183,P49903,P33981,Q13131,Q13043,P24941,P23919,Q9HA64,P51617,Q99640,P35790,Q16512,P60891,Q16539,P48729,Q00534,P42356,Q02750,Q13572,Q9H4A3,Q9BRR6,Q9HBU6,Q13535,Q9P289,Q9H2G2,Q14012,P14618,P17612,Q96KB5,P19525,P51570,P15531,O00764,P78356,P31751,O60566,P49841,Q8NEB9,O75116,Q13177,Q9Y3D8,P78527,P22392,Q13546,Q99986,Q00535,O14874,P41240,Q96Q15,P12277,O95747,Q96SB4,Q9Y4B6,Q9UJ70,Q9Y223,P10398,Q9NYV4,P19784,O14965,P11908,P06493 66 +Initiation factor 0.5041266726334225 2.686950125803314 0.0072107718606497 0.5043963813587157 0.0699444870483028 37 Q9BY44,Q14232,P20042,P60228,Q9UBQ5,O75822,O15372,P78344,O00303,P05198,P23588,Q9NR50,Q14240,Q15056,Q9ULC4,P46199,Q7Z478,O75821,Q14152,P06730,O43432,Q9UI10,Q04637,P60842,O15371,P49770,O60841,Q9Y262,P55010,Q13144,P55884 31 +tRNA-binding 0.6149879045896954 2.4897400712530007 0.0127836549818904 0.7129241163018871 0.1033345444369481 19 Q13325,Q7Z4G4,Q9NXH9,Q9UBP6,Q9HAV4,P38935,Q9H9T3 7 +Chaperone 0.3774129820541579 2.326369703090231 0.019998836447687 0.8590778180378091 0.1385633668161175 102 Q9NQP4,O95433,Q9H2J4,Q99543,O75937,P25685,P20290,Q99733,Q9NPL8,O95429,Q01105,Q9UHV9,Q15813,Q16543,Q99471,P31689,Q92688,P78318,O15212,Q15814,Q969U7,Q15785,Q99615,O95817,P04792,O95456,O75832,Q9UHD1,Q8WXX5,O60884,P61758 31 +Calmodulin-binding 0.443606254808468 2.125775796292923 0.0335219322618236 0.963387929061718 0.1915801061779413 35 O43815,Q01844,P49006,O60869,Q5T4S7,Q14012,Q99439,Q15051 8 +Serine/threonine-protein kinase 0.373841645070797 2.0992693639171236 0.0357931624571097 0.9708586230134004 0.1915801061779413 73 Q99570,P42345,P36507,P33981,Q13131,Q13043,P24941,P51617,Q16512,Q99640,Q16539,P48729,Q00534,Q02750,Q9H4A3,Q13535,Q9P289,Q9H2G2,Q14012,P17612,Q96KB5,P19525,P31751,P49841,O60566,O75116,Q13177,P78527,Q13546,Q99986,Q00535,Q96Q15,Q96SB4,Q9Y4B6,P10398,Q9NYV4,O14965,P19784,O95747,P06493 40 +Protein phosphatase 0.5314356475003053 1.963328117325652 0.0496080603520396 0.9928126928730264 0.2187264479158113 19 Q9UNI6,O60942,Q99504,A6NDG6,O15355,Q06124,P51452 7 +Nuclease 0.4038536174113296 1.8324485875252263 0.066884614834092 0.9987873681769502 0.2522936184627002 38 Q8IV08,Q9UQ84,Q9BQ61,Q8N2A8,Q9UPY3,Q9HB07,Q15631 7 +Endonuclease 0.4980386672988986 1.816398323853936 0.0693092921390592 0.999057846524655 0.2522936184627002 21 Q9UPY3,Q9UQ84,Q8N2A8,Q15631 4 +Threonine protease 0.9427235534774993 1.8104498240211064 0.0702260587473495 0.9991437415000474 0.2522936184627002 3 P28074,P28072 2 +Protease 0.3442062429820036 1.77050054994972 0.0766437928564891 0.99956265971537 0.2606672747242486 90 Q9BYT8,Q96FZ2,O43847,Q92995,P28074,Q96E52,P81605,Q96K76,Q9H3G5,Q14674,Q99436,Q96FW1,Q86TI2,P42785,Q96RU2,P40818,Q96KP4,Q4J6C6,Q01804,Q6P179,P52888,P28072,P48147,O94966,Q92905 25 +Cytokine 0.7908372938364469 1.7492860031290685 0.080241594191605 0.999700528661646 0.2606672747242486 4 P06744,P43490 2 +Thiol protease inhibitor 0.7342313108110414 1.5117545805792514 0.1305963078330525 0.9999987280103412 0.372583584111944 4 P04080,P98170 2 +Growth factor 0.7147033031277568 1.429183130029668 0.1529516051494259 0.999999898352264 0.4046187444339242 4 P06744,P55145,P51858 3 +Protease inhibitor 0.5380854918950867 1.4112345201899483 0.158175474646967 0.9999999442181784 0.4046187444339242 9 P04080,P30740,P30086,P98170 4 +Metalloprotease 0.4003777889562149 1.382386397400258 0.1668530904882161 0.9999999795829024 0.4046187444339242 27 Q6P179,O43847,Q96KP4,Q96E52,Q92905 5 +Allosteric enzyme 0.421351261941337 1.3205876575473428 0.1866388904518929 0.9999999980162356 0.4350770809989448 22 P13807,P06737,Q9Y3Z3,Q06203,Q13177,Q9Y223,Q14012,O60701 8 +Carboxypeptidase 0.5943049504079418 1.2477986278101925 0.2121048113384047 0.9999999999093352 0.4572037044405613 6 P42785,Q9H3G5 2 +Multifunctional enzyme 0.313783463023211 0.9561453422257868 0.3389988096470211 1.0 0.6908001330125473 34 Q13630,P30041,O60942,P34913,Q14527,Q08426,P50747,Q9Y223 8 +Exonuclease 0.3690000777453944 0.9043539326620844 0.3658077572433891 1.0 0.7241500500532396 20 Q8IV08,Q9BQ61,Q9UQ84 3 +Methyltransferase 0.2816635349244479 0.8372095899455083 0.4024747679046319 1.0 0.7366047639009301 51 Q86TU7,Q7Z4G4,Q9NXH9,O60678,Q9UBP6,Q6P2P2,Q9HBK9,Q86X55,O96028,Q9BV86,Q8IZ69,Q96P11 12 +Protein phosphatase inhibitor 0.5375277256444444 0.6925629590465389 0.4885838624950971 1.0 0.8314497309127091 4 Q96C90 1 +Rotamase 0.3129617878148478 0.6234878620147898 0.5329639761734133 1.0 0.8634970194584946 24 Q96AY3,P62942 2 +Actin capping 0.4283206553539941 0.621726280626721 0.5341218677062853 1.0 0.8634970194584946 7 P52907,P47755,Q01082,Q13813,P35241,P47756 6 +Serine protease 0.3895226333025418 0.5657006593258268 0.5715972869568293 1.0 0.8916125042281424 8 Q86TI2,Q4J6C6,P48147 3 +Aminopeptidase 0.353835443522968 0.5547165800546724 0.5790885336739482 1.0 0.8916125042281424 12 Q6P179 1 +Muscle protein 0.4613776088621854 0.5036006965470123 0.6145420030074864 1.0 0.917292600900056 5 P67936,P06753 2 +Elongation factor 0.3272960763934488 0.396373683723887 0.6918293769896069 1.0 0.9888562236056784 11 P24534,P26641,P29692,P63241,Q9Y450,Q05639 6 +Tyrosine-protein kinase 0.3231079054156609 0.3780772460774277 0.7053732109703954 1.0 0.9888562236056784 11 P36507,P19525,Q02750,P33981 4 +Thiol protease 0.2305285528541253 0.304083394697903 0.761064357315167 1.0 0.9888562236056784 35 Q01804,Q96K76,Q96FW1,Q92995,P40818,Q14674,O94966 7 +Tumor antigen 0.4853712197972235 0.2147572475075878 0.8299565866746801 1.0 0.9951929870263192 3 Q96RS6 1 +Serine protease inhibitor 0.3557728844625444 0.1810288527146012 0.8563449289638134 1.0 0.9951929870263192 5 P30086 1 +Nucleotidyltransferase 0.2266904478498439 0.1610216754822885 0.8720763288374962 1.0 0.9951929870263192 24 Q5TAX3 1 +Peroxidase 0.2680012989170311 0.06553502087376 0.9477480236311856 1.0 1.0 6 P30041 1 +Aminoacyl-tRNA synthetase 0.1724159572079958 0.0496571078953541 0.9603956372048406 1.0 1.0 32 Q9HA77,P54577,P49589,Q9Y285,P26639,P49591,P26640,Q9NSD9,A2RTX5,O43776 10 +Actin-binding 0.1830873421684781 0.0184186767085458 0.985304853110875 1.0 1.0 87 Q16658,O15144,P47755,O60610,O15357,Q15417,P35080,Q12792,P57737,Q8WX93,Q9Y281,P07737,Q9Y2J2,P06753,Q5T1M5,O15145,Q86TU7,P67936,P18206,P23528,Q01518,P35241,Q14019,P29966,Q99439,Q27J81,Q8N8S7,Q13045,P49006,P60981,Q9UEY8,Q6IBS0,Q9UHB6 33 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..37f4c5febf936b68cdfe199ab3eb8a008e054fea --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "AKT3", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APP", "APRT", "AQR", "ARAF", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD8", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C12orf43", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COASY", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP2", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EFNB1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERO1A", "ERP44", "ESCO2", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPD2", "GPHN", "GPI", "GPR89B", "GPSM1", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT3", "HIP1", "HIRA", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INF2", "ING5", "INPPL1", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4K4", "MAPK1", "MAPK14", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MATR3", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFN1", "MFN2", "MGA", "MGEA5", "MGME1", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NACC1", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NELFCD", "NELFE", "NES", "NF1", "NFRKB", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NUS1", "NUSAP1", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGK", "PIK3C2A", "PIK3C3", "PIK3R4", "PIN1", "PIN4", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R14B", "PPP1R8", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD54B", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBF1", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF12", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SVIL", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLK2", "TMCO1", "TMEM109", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UIMC1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP13", "USP14", "USP15", "USP19", "USP24", "USP28", "USP30", "USP32", "USP33", "USP36", "USP38", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR47", "WDR48", "WDR5", "WNK1", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H13", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZMAT2", "ZMPSTE24", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ADD3", "ADK", "ADPGK", "AHSA1", "AK6", "AKT2", "ANP32B", "ARAF", "ARPC2", "ARPC3", "AS3MT", "ATR", "AURKA", "BAG3", "BAG4", "BCKDK", "BTF3", "BUB1B", "CAMK1", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CDC37", "CDK1", "CDK12", "CDK2", "CDK5", "CDK6", "CFL1", "CFL2", "CHKA", "CHORDC1", "CKB", "CNDP2", "CNN2", "CNN3", "COPS5", "CORO7", "COTL1", "CPVL", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "DCAF1", "DCD", "DHX29", "DIAPH1", "DICER1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DPP9", "DSTN", "DTYMK", "DUSP12", "DUSP3", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3J", "EIF3K", "EIF3L", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELP3", "ENAH", "EPB41L3", "EPHX2", "ERAP2", "ESPL1", "ETNK1", "EWSR1", "EXO1", "EYA3", "FARSA", "FARSB", "FKBP10", "FKBP15", "FKBP1A", "FLII", "FN3KRP", "FSCN1", "GALK1", "GNE", "GPI", "GSK3B", "GYS1", "HBS1L", "HDGF", "HLCS", "HLTF", "HMCES", "HSPB1", "IFIT5", "IGBP1", "IGHMBP2", "INF2", "INPPL1", "IQCB1", "IRAK1", "ITPK1", "LIMA1", "MANF", "MAP2K1", "MAP2K2", "MAPK14", "MARCKS", "MARCKSL1", "MCTS1", "METTL1", "MTIF2", "MTOR", "MYG1", "NAGK", "NAMPT", "NAP1L4", "NARS", "NLN", "NME1", "NME2", "NRDC", "NSD2", "NSUN5", "NTMT1", "NUDCD1", "OMA1", "OTUB1", "OTUD4", "OXSR1", "PAK2", "PALLD", "PBK", "PDCL3", "PDXK", "PEBP1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKM", "PFN1", "PFN2", "PGP", "PI4KA", "PIK3C3", "PIK3R4", "PIP4K2B", "PKM", "PKMYT1", "PKN1", "PLD3", "PLD6", "PPAT", "PPM1G", "PPP1R14B", "PRCP", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKDC", "PRMT3", "PRMT9", "PRPS1", "PRPS2", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMG1", "PSMG2", "PTPN11", "PYGL", "RDX", "RIPK1", "RNGTT", "ROCK2", "SAMHD1", "SARS", "SEPHS1", "SERPINB1", "SET", "SETD3", "SLK", "SMG1", "SPTAN1", "SPTBN1", "SRPK1", "STK26", "STK4", "STRN", "TARS", "TARSL2", "TBCC", "TBCE", "THOP1", "TIMMDC1", "TK1", "TOMM34", "TPM3", "TPM4", "TRIR", "TRMT1", "TRMT11", "TRMT2A", "TSN", "TSTA3", "TTK", "TWF1", "TWF2", "UBR4", "UGDH", "USP13", "USP19", "USP28", "USP47", "USP8", "VARS1", "VBP1", "VCL", "VRK1", "WNK1", "XIAP", "XPO5", "YARS", "ZCCHC11"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..04543471279b3917b8b50a65d321c0e35e731d1f --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Enzymes", "1": "FDA approved drug targets"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..63d9b0b0ee95b5d6cbda0463b359389aa1a393eb --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d44016dcb411fe9a9801e79fcfd802466d6076cc8f7321280186771f08442a1 +size 219354 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c46c1cf35edb4004492de06afd57bbe21bfbba24 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4890191bb01ce4f4bd96e4146aabfb010e05b60fae8aa8a5e41fd5f0e25c1db9 +size 204884 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4f03aff6e40ab849986c5b83b7884654cd01c40e --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Enzymes", "1": "FDA approved drug targets", "2": "Predicted secreted proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2ebec5ab12459ec1e2bfe635777e651da21e09e9 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b837e9818bafa1b7f07370a9554838766c83ebb12ff4d5c89916012acffdb83 +size 132140 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..085706d4afe537263614b802d3aae1ada418aaa6 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e57fb545400f5ad42019879628406a64a496d8cd19ae58d4d7438476ea991273 +size 149098 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..504169c463be1b9b017e3579400cdf5b9e0718b4 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:54acdc26c055887929775548fecb6bb45e12592f8ce41482658b752f5b482017 +size 139133 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d1186881231c394894c06bf1a0e1783e88ac991e --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b7a19cf11ff01ed1c51904c7d091f354856430c59f41c2344e48519452eab6ca +size 108995 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1853bb58db3fcaf184c585d65e06a97bce05f3d0 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted intracellular proteins 1236 3173 inf 0.0 1052.9126213592233 2930.233009708738 -5.248196350890207 0.108353777008802 367.4824441165934 294.4528727150831 7.24167812525605 0.3049463326237019 0.8975088269741103 0.947672518459584 0.5773709653458103 0.0068928625647767 5.1564957123651294e-08 +Enzymes 142 994 3.269887969676305 0.0010759008553042 180.46601941747576 916.0339805825242 -0.3890709639022823 0.4315149002113257 67.0110577071333 90.66568168613344 1.858068218066602 0.4271937700203886 0.2428403295358605 9.847556396562472e-05 5.946444327953239e-06 5.344569994509285e-09 5.227985076378736e-07 +FDA approved drug targets 13 127 3.226793932520708 0.0012518558092151 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 1.0 7.258701529937447e-05 0.000145068056653 0.015715172052959 0.2178921442474439 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..04e4914b4eca0db3450ef54f115ccb4d9358eb61 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3425, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 520.6666666666666 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0c200a4b903944c091a662be5a13dbc3557f6352 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C137/C137_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8d37f077e56680fc96079a9721d7fda061bed87 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Enzymes 0.2331774398975234 3.2698879696763052 0.0010759008553042 0.0223524782265593 0.004588362627548 994 Q9H773,P48735,P00374,P34913,O75874,P49721,Q9NPH0,Q969T7,P28070,Q9UBM7,Q96E52,Q9HA64,P35790,P03886,Q16539,P19474,Q96AY3,Q9H4L7,P20618,O43813,Q5TAX3,Q9H3G5,Q13126,Q9BQG2,Q9HBU6,Q9UBP6,Q15125,Q96G23,Q0VDG4,O96028,Q14012,O14646,Q96PU5,Q9UNI6,Q16850,Q96JJ7,Q06203,Q4J6C6,Q9HBK9,Q9P2T1,P46934,P43490,O14874,O60942,Q01804,Q6P179,Q96Q15,Q86UY6,Q9UPP1,Q15392,P28161,P28072,P21266,P10398,Q86X55,Q9UKK9,Q04760,P49720,O75306,P62942,O95155,P15586,P98170,Q96C86,Q92995,P35270,P16930,P28074,Q13526,Q9BSD7,Q6SZW1,P42356,Q13535,P60900,Q14674,Q9H9P8,Q9BRF8,Q96KB5,P46976,P25788,P15531,Q99436,Q96FW1,Q86TI2,Q12873,P42785,P37837,Q9Y3D8,Q9BV86,P28066,P13807,Q13614,P49427,Q9Y285,Q9HCE1,Q96SZ6,Q6QHF9,O60502,P51452,P38935,P13051,O95260,Q96SZ5,Q92905,Q9UN37,Q8WUX2,P51665,O43847,P33981,Q9UPY3,Q96J02,Q16512,P51003,Q14527,Q7L014,Q9H1B7,Q12765,P23396,P06744,P25789,P34949,Q8NEB9,Q6DKJ4,Q7L5N1,Q96KP4,Q13907,Q15386,Q01968,P22392,P17174,O00625,Q8IV08,Q96SB4,Q9UJ70,Q9Y223,Q6P2P2,O94966,O95747,P11908,P25786,P49915,Q9BYT8 142 +FDA approved drug targets 0.3963724909397798 3.226793932520708 0.0012518558092151 0.0259624665772516 0.004588362627548 127 P48735,P00374,P62942,P20618,O75874,Q99720,Q16850,P98170,P04083,P49721,P20645,P04150,P03886 13 +Predicted secreted proteins 0.3682684886878122 1.8116361810078487 0.0700424305700633 0.7823664689635965 0.1634323379968144 56 P09429,Q6P179,P04083,O60888,P43490,Q9UMX5,P81605,P80303,P51858 9 +Citric acid cycle related proteins 0.4420093960543642 1.5965470785883529 0.1103667035781863 0.914210999563318 0.1931417312618261 25 P48735 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..893c656186e7c5051c7b415279921106e63038dd --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C1orf52", "C2CD5", "C2orf49", "C3orf58", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPI", "CENPV", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COASY", "COG3", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM210B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FPGS", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT3", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF13B", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMTOR1", "LAMTOR2", "LAMTOR3", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK3", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "METTL3", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPDZ", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL21", "MRPL28", "MRPL3", "MRPL33", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR3C1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3C3", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", 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O75874,Q9UQ84,Q8WW12,A6NDG6,P15927,Q13043,Q15477,Q92674,Q9NVH2,Q9NYB0,Q9BXJ9,Q15056,Q9NWV8,P83916,Q9Y450,Q9Y4R8,O75153,Q99436,P54277,Q969U7,Q96RU2,Q9C0C9,Q9BTV6,Q27J81,Q659A1,Q8NEM2,Q96BP3,P55199,Q7Z4G4,Q96DY7,P38935,P25786,Q8IYU2 33 +Centrosome 0.283496638868702 0.9845564234923616 0.3248420033543455 0.999997653726026 0.5641992689838633 80 Q9BRT9,P39687,Q5SW79,Q8IWC1,Q9UJW0,Q6QHF9,Q92688,Q3YEC7,Q9Y3D8,Q9UKK9,P28074,Q5T4S7,Q96CS2,P25786,O43237,Q9HD42 16 +Midbody ring 0.5250928082935966 0.9280366480220568 0.3533885597342385 0.9999994360615876 0.5830911235614936 6 Q06203 1 +Cytokinetic bridge 0.325274203686335 0.8422387062554987 0.399654352166523 0.999999951331821 0.6280282676902504 28 Q15051,Q9BVA1,P61201,Q9BUF5,Q14203,P07437,P17612,Q16512,Q15019,P04350 10 +Lysosomes 0.2956148403591453 0.3143188874802541 0.753278854496086 1.0 0.9008651858344836 13 Q13596,Q9UNH7,O60749 3 +Intermediate filaments 0.1801416645583338 0.0662963745370555 0.9471418695770184 1.0 0.9994427162539036 35 Q96K76,Q96G03,O60884,Q9Y496,O75351,Q99471,O75832,P07196,Q15102 9 +Golgi apparatus 0.2014220824616489 0.0573982698956166 0.9542279411552912 1.0 0.9994427162539036 185 Q93034,Q9UJY5,Q96A49,P48444,Q5VZ89,O43617,Q6NTF9,Q8N4Q0,O15260,Q9UID3,Q9UP83,Q99640,Q9HD45,P55327,Q86YR5,P80303,Q9BTX7,Q9BSL1,P24390,Q9HD26,O75794,O00461,P83436,P50851,Q8IXU6,Q8N3C0,Q9Y678,Q86VS8,Q9H3P7,Q13535,Q96P16,Q9NW68,Q8TD16,P51570,P35606,O15212,P52701,P26641,Q8IWJ2,P40818,O95456,O00203,Q9BQA1,Q9C005,Q99598,P18858,O60763,Q6P179,O95067,Q8N6T3,Q86VP6,A2RRP1,O75122,Q9UBU6 54 +Actin filaments 0.1741879662513036 0.0386661352827911 0.9691565733371186 1.0 0.9994427162539036 50 O94967,Q9Y6E2,Q6P4Q7,P49006,P26639,Q15942,P67936,Q06124,Q9UHD8,Q15417,Q99439,P06753,Q99460,Q15019,Q9UHB6,P17812 16 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..382a4cfae8250da5f51f079947ff3354dc15e868 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD14B", "ABHD6", "ABRACL", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADAM17", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "AKT3", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARRB1", "ARRB2", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATF7IP", "ATG3", "ATG4B", "ATG5", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BABAM1", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRD8", "BRI3BP", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C15orf39", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C1orf52", "C2CD5", "C2orf49", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPI", "CENPV", "CEP170", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG3", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH7", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "E2F3", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELP1", "ELP2", "ELP3", "ELP4", "ELP6", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESCO2", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC9", "EXT2", "EYA3", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM136A", "FAM162A", "FAM192A", "FAM208A", "FAM210B", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPR107", "GPR89B", "GPS1", "GPSM1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACE1", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HGH1", "HGS", "HIBCH", "HIGD1A", "HIKESHI", "HINT3", "HIP1", "HIRA", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDM5C", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMTOR1", "LAMTOR2", "LAMTOR4", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYPLAL1", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K6", "MAP3K4", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MBTD1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED25", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL14", "METTL16", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGA", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL21", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NACC1", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK1", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NFATC2IP", "NFKBIE", "NFRKB", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NR3C1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUS1", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PATL1", "PAX6", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2B", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA7", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPID", "PPIE", "PPIF", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBFA", "RBFOX2", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RBPMS", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNF14", "RNF169", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIN3B", "SIPA1", "SIRT1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SVIL", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF15", "TAF5", "TAF6", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM41A", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC2L", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC28", "TTC37", "TTC38", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC16", "TXNDC5", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBP1", "UBQLN1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UIMC1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP13", "USP14", "USP15", "USP24", "USP28", "USP32", "USP33", "USP36", "USP38", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDHD1", "WDR1", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR7", "WDR70", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM2", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAGAB", "AARSD1", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD14B", "ABRACL", "ABRAXAS2", "ACAT2", "ACBD3", "ACLY", "ACO1", "ACOT7", "ACTR1A", "ACTR2", "ADK", "ADSS", "AGL", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK6", "AKAP12", "AKAP8", "AKT1S1", "AKT2", "AMPD2", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA7", "AP3B1", "AP3D1", "APRT", "ARCN1", "ARF6", "ARFGAP1", "ARMC6", "ARMC8", "ASCC2", "ASCC3", "ASH2L", "ASNS", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATR", "ATXN2L", "AURKA", "BABAM1", "BAG3", "BAIAP2", "BCCIP", "BCR", "BICD2", "BLVRA", "BRAP", "BSDC1", "BTAF1", "BTF3", "BUB1B", "BZW2", "C15orf39", "C1orf123", "C1orf35", "C8orf33", "CACUL1", "CACYBP", "CALCOCO2", "CAMK1", "CAND1", "CAND2", "CAP1", "CAPZA2", "CARM1", "CARS", "CAST", "CBX1", "CBX8", "CCDC124", "CCDC6", "CCNB2", "CCT2", "CDC123", "CDC34", "CDC37", "CDK1", "CDK2", "CDK6", "CENPI", "CEP170", "CETN2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHD1", "CHD3", "CHD8", "CHMP1A", "CHMP5", "CHORDC1", "CIP2A", "CIRBP", "CKB", "CLASP2", "CLIC1", "CLINT1", "CLTB", "CLUH", "CNDP2", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNPY2", "COG5", "COG7", "COPA", "COPB1", "COPB2", "COPG1", "COPS2", "COPS3", "COPS5", "COPS6", "COPS7A", "COPS8", "COTL1", "CPPED1", "CPSF7", "CRKL", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CTPS1", "CTPS2", "CTTN", "CTTNBP2NL", "CUL5", "CUTA", "CWC22", "DCAF16", "DCPS", "DCTN1", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DDX6", "DENND4C", "DIAPH1", "DICER1", "DIS3", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM2", "DNPH1", "DOCK6", "DPH7", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG2", "DTL", "DTX3L", "DUS2", "DUSP12", "DUSP3", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "E2F3", "ECD", "ECT2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3J", "EIF3K", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELL", "ELMO2", "ELOA", "ELP1", "ELP3", "EML4", "ENAH", "ENSA", "EPHX2", "ERAP2", "ERCC2", "ESD", "ESPL1", "ETNK1", "EWSR1", "EXO1", "EXOC7", "EXOC8", "FAF1", "FAH", "FAM120A", "FAM120B", "FAM129B", "FAM210B", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FANCD2", "FANCI", "FARP1", "FARSA", "FARSB", "FASN", "FDPS", "FEN1", "FERMT2", "FHL1", "FKBP15", "FKBP3", "FKBP4", "FLAD1", "FLII", "FMR1", "FN3KRP", "FOXK1", "FSCN1", "FUBP1", "FXR1", "G3BP1", "G3BP2", "GABARAPL2", "GALK1", "GART", "GCAT", "GCC2", "GCFC2", "GCN1", "GDI2", "GGA1", "GINS2", "GINS4", "GLO1", "GLOD4", "GLRX", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNE", "GOLIM4", "GOPC", "GOT1", "GPHN", "GPI", "GPSM1", "GSK3B", "GSPT1", "GSR", "GSTM2", "GSTM3", "GTF2E1", "GTF2F2", "GYS1", "HACE1", "HAUS1", "HBS1L", "HDGF", "HDGFL2", "HEATR3", "HEBP1", "HGH1", "HGS", "HINT3", "HLCS", "HLTF", "HMGB1", "HMGB3", "HMMR", "HNRNPF", "HNRNPLL", "HOOK3", "HSP90AA1", "HSP90AB1", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "ICE2", "IDH1", "IGBP1", "IGF2BP2", "IGHMBP2", "INA", "INF2", "INPPL1", "INTS7", "IPO7", "IPO8", "IQCB1", "IRAK1", "IRF2BPL", "ISYNA1", "ITCH", "ITPA", "JMJD6", "KAT7", "KCTD21", "KDELR1", "KIF1A", "KIF3A", "KLC1", "KPNA1", "KPNA3", "KPNA6", "LANCL1", "LARP1", "LARP4B", "LARP7", "LDHA", "LGALS3", "LIG1", "LIMA1", "LNPK", "LRBA", "LRRC57", "LTA4H", "LTV1", "LUC7L2", "LYPLAL1", "MAGED2", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAP7D3", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MAT2A", "MCM4", "MCTS1", "ME1", "MED14", "METTL1", "METTL16", "MGEA5", "MIF", "MMS19", "MOCOS", "MOV10", "MPI", "MPST", "MRI1", "MSH6", "MTAP", "MTBP", "MTOR", "MYG1", "NAA10", "NAA15", "NAA35", "NAA40", "NAF1", "NAGK", "NAP1L1", "NAP1L4", "NARS", "NASP", "NBAS", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "NEDD4", "NEFL", "NELFCD", "NFATC2IP", "NFKBIE", "NME1", "NME2", "NOB1", "NOSIP", "NR3C1", "NRBP1", "NRDC", "NSD2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT5", "NXN", "OCRL", "OLA1", "OMA1", "OPA3", "ORC5", "OSBPL3", "OSGEP", "OTUB1", "OTUD4", "OXSR1", "PA2G4", "PABPC4", "PACSIN2", "PACSIN3", "PAFAH1B3", "PALLD", "PANK4", "PAOX", "PAPOLA", "PARG", "PARK7", "PBDC1", "PBK", "PBXIP1", "PCBD1", "PCNP", "PDAP1", "PDCD4", "PDCD5", "PDCL3", "PDLIM5", "PEBP1", "PFDN2", "PFDN5", "PFDN6", "PFN1", "PGLS", "PGM1", "PGM2", "PGP", "PHAX", "PHF8", "PI4KA", "PIGU", "PIK3R4", "PIN1", "PIP4K2B", "PIR", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PLD3", "PLXNA1", "PMF1", "PMS1", "PNP", "POLE", "POLR3E", "PPAT", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP5C", "PPP6R3", "PPWD1", "PRDX6", "PREP", "PRKAA1", "PRKACA", "PRKRA", "PRMT9", "PRPSAP1", "PRPSAP2", "PRRC2A", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD12", "PSMD13", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSMG1", "PSMG2", "PTBP2", "PTPA", "PTPN11", "PYGB", "PYGL", "QRICH1", "RAB3GAP1", "RABL6", "RAD23A", "RAD23B", "RANBP3", "RBFOX2", "RBM12", "RBM3", "RBM42", "RBPMS", "RHBDD2", "RIPK1", "RNF169", "RNF219", "RNGTT", "ROCK2", "RPA2", "RPL10", "RPL10A", "RPL13", "RPL17", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL27A", "RPL29", "RPL3", "RPL36A", "RPL37A", "RPL5", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPS10", "RPS11", "RPS15", "RPS17", "RPS18", "RPS2", "RPS23", "RPS24", "RPS3", "RPS3A", "RPS6", "RPS7", "RPS8", "RPSA", "RRM1", "RRM2", "RTCA", "RTF1", "RUFY1", "SAE1", "SAMHD1", "SAP30BP", "SARS", "SCRN1", "SCRN3", "SDCBP", "SEC23A", "SEC24B", "SEC31A", "SEPT2", "SEPT9", "SERBP1", "SET", "SH3GL1", "SH3PXD2B", "SHCBP1", "SHMT1", "SKA3", "SKIV2L", "SKP1", "SKP2", "SLC25A20", "SLC25A32", "SLC33A1", "SLC35F2", "SLC4A1AP", "SLC4A7", "SLFN11", "SLK", "SMARCAD1", "SMG1", "SNAP29", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SORBS3", "SPAG9", "SPART", "SPC25", "SPR", "SRI", "SRM", "SRPK1", "SRSF5", "SSB", "SSRP1", "STAT1", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STRAP", "STRN", "SURF4", "SYAP1", "TALDO1", "TARS", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCB", "TBCC", "TELO2", "TERF2IP", "TES", "TFCP2", "TFG", "THOP1", "THUMPD1", "THYN1", "TIGAR", "TIMELESS", "TIMMDC1", "TM9SF3", "TNPO1", "TOMM34", "TPD52", "TPM3", "TPM4", "TPRKB", "TPT1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM25", "TRIM26", "TRIP13", "TRIR", "TRMT1", "TRMT11", "TRMT112", "TRMT2A", "TRMT6", "TROVE2", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC1", "TTC28", "TTC37", "TTC38", "TTK", "TTPAL", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "TWF1", "TXLNG", "TXNL1", "UAP1", "UBA2", "UBA3", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2L3", "UBE2M", "UBE2O", "UBE3C", "UBR4", "UBXN1", "UBXN7", "UHRF1BP1", "UMPS", "UNC45A", "UNG", "UPF2", "URGCP", "USO1", "USP13", "USP14", "USP24", "USP28", "USP4", "USP47", "USP8", "VARS1", "VBP1", "VPS4B", "VPS51", "VRK1", "VRK3", "VTA1", "WARS", "WDR47", "WDR61", "WDR62", "WDR7", "WDR70", "WDR77", "WNK1", "XIAP", "XPNPEP1", "XPO1", "XPO4", "XPO5", "XPOT", "YARS", "YBX1", "YBX3", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H15", "ZCCHC11", "ZFYVE16", "ZNF207", "ZYX"]} \ No newline at end of file