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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Tyrosine-protein kinase, active site [IPR008266]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:f9c72de81fb6d2866d9947f51cca67a40eed875340b1b19433563c19fa1f3bea
+size 75082

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.6315789473684212
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C140/C140_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9666977902272024	1.887837854988231	0.0590477214905147	0.9688575267975708	0.280476677079945	3	P10619,Q9HB40	2
+Histidine acid phosphatase active site [IPR033379]	0.9517734909769774	1.318754960882226	0.1872510459411254	0.9999926291784276	0.4592202801297532	2	Q9NPH0	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.4645573587944443	0.5559859212958916	0.5782204792333396	1.0	0.8356831465626202	6	Q9H3S7	1
+Tyrosine-protein kinase, active site [IPR008266]	0.3274143302180771	0.0692526218868143	0.9447885374026648	1.0	0.9616597612848552	6	P12931,Q13308,Q15375,P23458,P07947	5

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAPN1", "CAPN2", "CASP7", "CASP8", "CDC34", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "JAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAPK1", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME3", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRC", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CTSA", "EPHA7", "JAK1", "PTK7", "PTPN23", "SCPEP1", "SRC", "YES1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:f32406fc44dd27e847599f5871b78ca926e0f095c9a0f22e6d693f1dce41376b
+size 73349

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.645161290322581
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C140/C140_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.7380547894389402	1.5703041089768075	0.1163443787153353	0.978384047361081	0.3367676836041097	5	P14735,P22695,O43847	3
+EF-Hand 1, calcium-binding site [IPR018247]	0.4396916546489781	1.2588174328300068	0.2080962821589673	0.9992774900389474	0.4607846247805706	35	Q14257,Q02818,P80303,Q9NWM8,Q9Y680	5
+Beta tubulin, autoregulation binding site [IPR013838]	0.6929571120470897	1.179286572624847	0.2382840831425465	0.9997834371527768	0.4924537718279295	4	P68371,Q9BUF5	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APEX2", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK1", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "JAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["FKBP14", "FKBP7", "IDE", "NRDC", "NUCB1", "NUCB2", "RCN2", "TUBB4B", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:4b17ae6b9fe61cc652ce1ed02ab21a9601e465684c06d46cb33ef0530a69c6a0
+size 87496

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	4	8	2.099625035781201	0.0357618386641096	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0127069358947235	0.0470522829573702	0.0039135152062846	0.0014512760162947	5.383729574080712e-05

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 278,
+    "title": "Average number of proteins per term",
+    "value": 2.723021582733813
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C140/C140_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,38 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7827168807572751	2.099625035781201	0.0357618386641096	0.9999598911984158	0.3233642342285268	8	P28070,P28074,P28072,P49721	4
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.9084332744476272	2.032002729098007	0.0421533796651178	0.9999936863573518	0.3303442781739804	4	Q8N4Q0	1
+Intermediate filament protein, conserved site [IPR018039]	0.6556642385451091	1.5107866944518198	0.1308428057815616	1.0	0.5310701107759156	8	Q16352,P08670,P48681	3
+Haem oxygenase conserved site [IPR018207]	0.9775980087118864	1.4171562523790455	0.1564372490540633	1.0	0.5722309899609157	2	P09601	1
+Sterol reductase, conserved site [IPR018083]	0.969819539514624	1.3874807794934292	0.1652952080307441	1.0	0.5783261730396744	2	Q14739	1
+Tetraspanin, conserved site [IPR018503]	0.962041070317362	1.3578339767938277	0.1745163710620101	1.0	0.5916530628687661	2	O43657	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9489732420659616	1.3081096830828582	0.1908361096095667	1.0	0.6168888194355763	2	P04066	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.7989539434428851	1.2586076883299775	0.2081720686544408	1.0	0.6359542317135665	3	Q16836	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.598532906380797	1.1989026499192172	0.2305658012485563	1.0	0.6514849405521185	7	Q9P2W9,O60499	2
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6006286716440495	1.1742294544368663	0.2403031311949321	1.0	0.6602587439827553	6	P33993	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.7131187058838913	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.7131187058838913	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.7131187058838913	2	P05067	1
+ABC transporter-like, conserved site [IPR017871]	0.5370291023474894	1.0486009858506382	0.2943618019395475	1.0	0.7131187058838913	11	P33527,Q03518	2
+Tubulin, conserved site [IPR017975]	0.6090442574492719	1.0167651665692767	0.3092651565923616	1.0	0.7164642794389712	5	P68371,Q9BUF5	2
+Guanylate kinase, conserved site [IPR020590]	0.6040931671505896	0.995565333153863	0.3194613856084336	1.0	0.727952993435611	5	Q00013	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5446292189237872	0.975007081761528	0.3295567471538239	1.0	0.7329342056701044	8	P05091,P51648,O94788	3
+FERM conserved site [IPR019747]	0.492080665250281	0.7502664725699443	0.4530942310609533	1.0	0.8673731913114003	9	O94887	1
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.4965962634148197	0.7442569473511113	0.456721041873803	1.0	0.8673731913114003	8	P05091,P51648,O94788	3
+Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]	0.5183973026670723	0.6376624601965938	0.5236934272780025	1.0	0.8823440774744528	5	Q13011	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7485998755444979	0.5909371487137831	0.5545625340254965	1.0	0.9022558542713875	2	P01889	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.445364719025931	0.5503006009240415	0.5821132121432282	1.0	0.91947427827169	10	Q06136,Q53GQ0	2
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.4731791905631204	0.4624970861780877	0.6437248914031506	1.0	0.9509960276570242	5	P48735	1
+Chromo domain, conserved site [IPR023779]	0.4551681195516791	0.3139353186959526	0.7535701649899111	1.0	1.0	4	P45973,Q13185,O14646	3
+Thioredoxin, conserved site [IPR017937]	0.378520714781591	0.2621070270361666	0.7932389293337756	1.0	1.0	11	O95881,Q9H1E5,Q96JJ7	3
+Dynamin, GTPase region, conserved site [IPR019762]	0.5762289981331736	0.175485178718958	0.860698415744356	1.0	1.0	2	P50570	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4403983815748679	0.1633314590125943	0.870257465762649	1.0	1.0	3	P14625,P08238	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.4257703081232502	0.1423179464485789	0.8868288715952448	1.0	1.0	3	O75521,Q5T8D3	2
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4220354808590127	0.13736488894896	0.8907423824842571	1.0	1.0	3	Q9Y2T2,Q9BXS5	2
+DnaJ domain, conserved site [IPR018253]	0.3409812471235694	0.1117008627427177	0.9110605952429638	1.0	1.0	11	Q99543,Q96KC8,Q9NVH1	3
+Oxysterol-binding protein, conserved site [IPR018494]	0.3382333259607291	0.0972266458271113	0.922546407974846	1.0	1.0	6	Q9BXW6	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.4919103920348543	0.0860832537458513	0.9314002357787812	1.0	1.0	2	P28340	1
+Profilin conserved site [IPR027310]	0.490976975731182	0.0854725710206954	0.9318857008104202	1.0	1.0	2	P07737	1
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.4741754822650922	0.0756518075474008	0.9396961180621866	1.0	1.0	2	Q96FJ2	1
+Ribosomal S11, conserved site [IPR018102]	0.3873677660236462	0.0511371807363354	0.9592162087938212	1.0	1.0	2	P82912	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.3771001866832555	0.0501045225292042	0.9600390958097612	1.0	1.0	2	P10644	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	1.0	2	P30876	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "ATR", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN2", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MNAT1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSD3", "NSF", "NSUN6", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCC1", "ACBD5", "ALDH1A2", "ALDH2", "ALDH3A2", "AP1M1", "AP3M1", "APP", "CBX3", "CBX5", "CHD1", "DNAJC1", "DNAJC11", "DNAJC2", "DNM2", "DYNLL2", "ECH1", "ECI2", "FARP2", "FUCA1", "HADH", "HLA-B", "HMOX1", "HSD17B12", "HSP90AB1", "HSP90B1", "IDH2", "INA", "KDSR", "LBR", "MCM7", "MPP1", "MRPS11", "NES", "OSBPL1A", "PFN1", "POLD1", "POLR2B", "PRKAR1A", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "STX10", "STX18", "TAP1", "TMX3", "TMX4", "TSPAN6", "TUBB4B", "TUBB6", "TXNDC12", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain, eukaryote [IPR003954]", "1": "Cytochrome b5-like heme/steroid binding domain [IPR001199]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain, eukaryote [IPR003954]", "1": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "2": "EF-hand domain [IPR002048]", "3": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "4": "SWAP/Surp [IPR000061]", "5": "K Homology domain, type 1 [IPR004088]", "6": "Gelsolin-like domain [IPR007123]", "7": "SAP domain [IPR003034]", "8": "K Homology domain [IPR004087]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:814d72e2aaeb501270bc426ae2f53d6418ebb386ad7ff90b999a40be830e9174
+size 160498

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+RNA recognition motif domain, eukaryote [IPR003954]	6	14	2.282948849074632	0.0224333815620445	4.084951456310679	13.157766990291265	0.4053633607283609	0.5044278905686779	2.611599730621696	1.3534791070715837	0.9876170990304802	0.3281969373801077	0.3123090606402261	0.0963063052639835	0.1837383274168749	0.4002719515071794	0.0003649926190301
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	5	6	2.269325795646275	0.0232485209793067	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0182106218415612	1.0	0.1094892401774078	0.0323840811666381	0.0001560226497295
+Alcohol dehydrogenase, N-terminal [IPR013154]	1	6	2.250229142938301	0.0244344032251173	1.3762135922330097	5.245145631067961	0.6000738304798152	0.3870290227769069	1.1994000251783288	0.9246362329357484	1.1062357688130569	0.3020782188917261	0.0102840817440213	0.0007972103198291	0.0031504918831051	0.018519525655472	0.0672800541821322
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	3	5	2.0925431048054377	0.036389960032976	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0080921331431007	0.0378187125466048	0.002465796513642	0.0146338936924203	0.0003260526470588
+Aminopeptidase N-like , N-terminal domain [IPR045357]	3	5	2.0925431048054377	0.036389960032976	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0080921331431007	0.0378187125466048	0.002465796513642	0.0146338936924203	0.0003260526470588
+Major facilitator superfamily domain [IPR020846]	3	5	2.0605648717391936	0.0393445709703452	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	0.414400038214874	1.0	1.0	0.1617118829485157	0.0550493127109652

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 2675,
+    "title": "Average number of proteins per term",
+    "value": 2.1865420560747664
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C140/C140_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,266 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+RNA recognition motif domain, eukaryote [IPR003954]	0.7402749354635961	2.2829488490746317	0.0224333815620445	1.0	0.5959081655917002	14	P38159,Q14011,Q9UHX1,Q01130,O95628,Q14498	6
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8461059190031204	2.269325795646275	0.0232485209793067	1.0	0.5959081655917002	6	O00264,Q8WUJ1,O15173,Q9UMX5,O43169	5
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.841590451226293	2.250229142938301	0.0244344032251173	1.0	0.5959081655917002	6	Q8N4Q0	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8636905513485071	2.0925431048054377	0.036389960032976	1.0	0.5959081655917002	5	P55786,Q9UIQ6,P09960	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8636905513485071	2.0925431048054377	0.036389960032976	1.0	0.5959081655917002	5	P55786,Q9UIQ6,P09960	3
+Major facilitator superfamily domain [IPR020846]	0.8558166236196342	2.0605648717391936	0.0393445709703452	1.0	0.5959081655917002	5	Q7L0J3,Q9H2V7,Q8NHS3	3
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7464565861061013	1.8849481274143167	0.0594368414948593	1.0	0.5959081655917002	7	Q8N4Q0	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9638966697790232	1.8774757767719956	0.0604529142715579	1.0	0.5959081655917002	3	Q15629,Q96G23	2
+EF-hand domain [IPR002048]	0.4855218280558411	1.8691653025299264	0.0615998199738219	1.0	0.5959081655917002	42	Q15293,Q14257,Q6KCM7,Q02818,O75746,Q96AY3,P80303,O75071,Q9NWM8,Q9UJS0,Q9Y680,O43852,Q8NF37,Q9H223	14
+Peptidase M16, C-terminal [IPR007863]	0.7419129466182844	1.86446327964772	0.0622566736203358	1.0	0.5959081655917002	7	P14735,P22695,Q5JRX3,O43847	4
+Peptidase M16, N-terminal [IPR011765]	0.7419129466182844	1.86446327964772	0.0622566736203358	1.0	0.5959081655917002	7	P14735,P22695,Q5JRX3,O43847	4
+Reticulon [IPR003388]	0.840760182973793	1.7689336809055292	0.0769049426590773	1.0	0.6079943740265851	4	O95197,Q9NQC3	2
+CBS domain [IPR000644]	0.7186812271837539	1.759054011346582	0.0785683351008854	1.0	0.6091455497336631	7	P51798,Q6P4Q7	2
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.6994852433604244	1.7177262255774322	0.0858465634677816	1.0	0.6191768454449748	8	Q04656,P35670,P23634,Q9HD20,P16615	5
+Zinc finger, CHHC-type [IPR012996]	0.8976034858387802	1.6302917993518062	0.1030398399509855	1.0	0.6307358624001975	3	P31943,P52597	2
+ERAP1-like C-terminal domain [IPR024571]	0.8954248366013038	1.6221143736846408	0.104778861071678	1.0	0.638658683525805	3	P55786,Q9UIQ6	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6915947551022301	1.5919865710037602	0.1113877219763685	1.0	0.6480634565543986	6	Q9NUQ2,Q9HCL2	2
+Zinc finger, CCHC-type [IPR001878]	0.6776658738683836	1.5703641731308249	0.1163304124163131	1.0	0.6497345862794287	7	Q9NUD5,Q5TAX3	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6736829827056061	1.551877686059656	0.1206914930076059	1.0	0.6497345862794287	7	P33527,Q03518	2
+Band 7 domain [IPR001107]	0.6630265289883357	1.5458056568386198	0.1221515104570094	1.0	0.6497345862794287	8	P27105	1
+Zinc finger, RanBP2-type [IPR001876]	0.6518431912364934	1.5383540134645994	0.1239620797489002	1.0	0.6501006764672177	9	Q01844,P35637,Q92804,P98175	4
+Intermediate filament, rod domain [IPR039008]	0.6556642385451091	1.5107866944518198	0.1308428057815616	1.0	0.663559348593751	8	Q16352,P08670,P48681	3
+Kinesin-associated [IPR032405]	0.7502978817164321	1.409390681867523	0.1587196778400263	1.0	0.684242541269034	4	O60333,Q15058	2
+FERM adjacent (FA) [IPR014847]	0.6977910385945536	1.3983933736744731	0.1619949719192508	1.0	0.6842975167338695	5	O94887	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8323505291135749	1.38452770529151	0.1661969307904889	1.0	0.6850997182849113	3	Q99797	1
+PRELI/MSF1 domain [IPR006797]	0.9648413192283768	1.3685031284395677	0.1711546434226365	1.0	0.6947476041814153	2	Q9Y255	1
+Heat shock chaperonin-binding [IPR006636]	0.687302521606896	1.35337666678598	0.1759353277763526	1.0	0.7010783157251046	5	Q9NRR5,P54725	2
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9489732420659616	1.3081096830828582	0.1908361096095667	1.0	0.7021823840517072	2	P04066	1
+MENTAL domain [IPR019498]	0.9461729931549488	1.2974704390233696	0.1944693699066491	1.0	0.7046467279083923	2	O95772	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9439950217797166	1.2891998590596825	0.1973286140260282	1.0	0.7046467279083923	2	Q8N2A8	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.6705076300217874	1.2811589083754331	0.2001378560352653	1.0	0.7053606915603884	5	P05023,P20020,P16615,P23634	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.6705076300217874	1.2811589083754331	0.2001378560352653	1.0	0.7053606915603884	5	P05023,P20020,P16615,P23634	4
+IMD/I-BAR domain [IPR013606]	0.9371499688861252	1.263233520606013	0.2065052695316378	1.0	0.7085348099211075	2	Q9UQB8	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.7989539434428851	1.2586076883299775	0.2081720686544408	1.0	0.7085348099211075	3	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.7989539434428851	1.2586076883299775	0.2081720686544408	1.0	0.7085348099211075	3	Q16836	1
+Death domain [IPR000488]	0.7936507936507904	1.238647938541228	0.2154759065878835	1.0	0.7142478935843722	3	Q12955,Q96FV9	2
+NOPS [IPR012975]	0.7886710239651404	1.2199198301419163	0.2224952676780991	1.0	0.7240569842322568	3	P23246,Q8WXF1	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9225264467952742	1.2079171859755349	0.2270791182941627	1.0	0.7300921171116409	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9225264467952742	1.2079171859755349	0.2270791182941627	1.0	0.7300921171116409	2	Q9Y282	1
+Peptidase M16, middle/third domain [IPR032632]	0.9178593652769176	1.1903149017692358	0.2339226459300285	1.0	0.7310082685313392	2	P14735	1
+MCM, AAA-lid domain [IPR041562]	0.6006286716440495	1.1742294544368663	0.2403031311949321	1.0	0.7431339606317268	6	P33993	1
+MCM OB domain [IPR033762]	0.6006286716440495	1.1742294544368663	0.2403031311949321	1.0	0.7431339606317268	6	P33993	1
+MCM domain [IPR001208]	0.6006286716440495	1.1742294544368663	0.2403031311949321	1.0	0.7431339606317268	6	P33993	1
+MCM N-terminal domain [IPR027925]	0.6006286716440495	1.1742294544368663	0.2403031311949321	1.0	0.7431339606317268	6	P33993	1
+EXPERA domain [IPR033118]	0.912881144990669	1.1715703296051474	0.2413696061098549	1.0	0.7447101457253309	2	Q5BJF2	1
+MD-2-related lipid-recognition domain [IPR003172]	0.9122588674548872	1.1692296355084832	0.2423111241030104	1.0	0.746017786407077	2	P61916	1
+Dbl homology (DH) domain [IPR000219]	0.5983237201026657	1.1635514928853057	0.2446058188659532	1.0	0.746017786407077	6	Q9H8V3,O94887	2
+Sterol-sensing domain [IPR000731]	0.9066583696328584	1.1481884285914354	0.2508907851341133	1.0	0.7523910877060013	2	P04035	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.6845755192304462	1.1457010603679438	0.2519188649628239	1.0	0.7538727595037104	4	Q16352,P08670	2
+Amino acid permease/ SLC12A domain [IPR004841]	0.768440709617181	1.1440259030223368	0.2526128947394226	1.0	0.7538727595037104	3	P55011,Q9Y666	2
+SLC12A transporter, C-terminal [IPR018491]	0.768440709617181	1.1440259030223368	0.2526128947394226	1.0	0.7538727595037104	3	P55011,Q9Y666	2
+Amine oxidase [IPR002937]	0.7634943731470797	1.1255273441336602	0.260365636744756	1.0	0.7687396007640422	3	Q8NB78	1
+FERM, C-terminal PH-like domain [IPR018980]	0.5737145856735679	1.1160272314862378	0.2644104783932999	1.0	0.7736770854682894	8	O94887	1
+FERM, N-terminal [IPR018979]	0.5737145856735679	1.1160272314862378	0.2644104783932999	1.0	0.7736770854682894	8	O94887	1
+OCRE domain [IPR041591]	0.8932794026135683	1.0981225576374067	0.2721509764765757	1.0	0.781959035526144	2	P98175	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8889234598631011	1.081888972168533	0.2793018656028958	1.0	0.7858479186441193	2	P98179	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7488328664799191	1.0708663437166683	0.2842295309265643	1.0	0.7878901504959167	3	P01889,P10321	2
+Immunoglobulin C1-set [IPR003597]	0.7488328664799191	1.0708663437166683	0.2842295309265643	1.0	0.7878901504959167	3	P01889,P10321	2
+MHC class I-like antigen recognition-like [IPR011161]	0.7488328664799191	1.0708663437166683	0.2842295309265643	1.0	0.7878901504959167	3	P01889,P10321	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7488328664799191	1.0708663437166683	0.2842295309265643	1.0	0.7878901504959167	3	P01889,P10321	2
+FAD-binding domain, PCMH-type [IPR016166]	0.8836341008089669	1.062225266794591	0.2881334319539974	1.0	0.7905885810027188	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8836341008089669	1.062225266794591	0.2881334319539974	1.0	0.7905885810027188	2	Q15392	1
+GOLD domain [IPR009038]	0.5696776572943765	1.062170135864673	0.2881584547580003	1.0	0.7905885810027188	7	Q15363,Q9Y3B3	2
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.88145612943373	1.054144642245065	0.2918167000935128	1.0	0.790720177941225	2	P05067	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5370291023474894	1.0486009858506382	0.2943618019395475	1.0	0.794308523171559	11	P33527,Q03518	2
+Kinesin-like KIF1-type [IPR022140]	0.7419678395641649	1.0453740432281564	0.2958501285278974	1.0	0.7943245958348674	3	O60333	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8783447417548245	1.0426179593704412	0.2971252680866545	1.0	0.7963674993279042	2	Q92945	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6090442574492719	1.0167651665692767	0.3092651565923616	1.0	0.8037178989964875	5	P68371,Q9BUF5	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6090442574492719	1.0167651665692767	0.3092651565923616	1.0	0.8037178989964875	5	P68371,Q9BUF5	2
+Dynamin, N-terminal [IPR045063]	0.5584804954250058	1.0091341659119706	0.312910294435796	1.0	0.8063921364313625	7	Q8IWA4,Q9H4M9,Q9H223	3
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5584804954250058	1.0091341659119706	0.312910294435796	1.0	0.8063921364313625	7	Q8IWA4,Q9H4M9,Q9H223	3
+Band 3 cytoplasmic domain [IPR013769]	0.8640323584318634	0.9898735994002292	0.3222359050611296	1.0	0.820934329560497	2	Q9Y6M7	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.8640323584318634	0.9898735994002292	0.3222359050611296	1.0	0.820934329560497	2	Q9Y6M7	1
+Sam68, tyrosine-rich domain [IPR032335]	0.8612321095208487	0.9796115963188295	0.3272778785729429	1.0	0.8270448228376712	2	O75525	1
+KHDRBS, Qua1 domain [IPR032571]	0.8612321095208487	0.9796115963188295	0.3272778785729429	1.0	0.8270448228376712	2	O75525	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8568761667703854	0.963688813929443	0.3352019641983006	1.0	0.8314278555812952	2	O15254	1
+CNNM, transmembrane domain [IPR002550]	0.8531425015556983	0.9500812728109586	0.3420709580238528	1.0	0.8327332373167048	2	Q6P4Q7	1
+Ion transporter-like, CBS domain [IPR044751]	0.8531425015556983	0.9500812728109586	0.3420709580238528	1.0	0.8327332373167048	2	Q6P4Q7	1
+START domain [IPR002913]	0.8515868077162467	0.9444228761851496	0.3449535959872678	1.0	0.8327332373167048	2	Q14849	1
+NSD, Cys-His rich domain [IPR041306]	0.85003111387679	0.9387713463793058	0.3478481533641393	1.0	0.8327332373167048	2	O96028	1
+Cyclin-like [IPR013763]	0.6304237274579326	0.9304314576594684	0.3521477373205477	1.0	0.8348699828280967	4	O95067	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8472308649657763	0.9286162362443782	0.3530880045003439	1.0	0.8348699828280967	2	O60506	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7027699968876333	0.901505172204178	0.3673197850514871	1.0	0.8488369634930218	3	O43823,Q9ULX6	2
+DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]	0.8332296204107085	0.8782018174129481	0.3798342059182515	1.0	0.8577224500834609	2	Q06609	1
+CARG-binding factor, N-terminal [IPR012956]	0.8304293714996911	0.8681957421665273	0.3852871847561512	1.0	0.8631852757309082	2	Q99729	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8279402613565645	0.8593242451746492	0.390161651456401	1.0	0.8671300516102446	2	Q9NVI7	1
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.8270068450529	0.8560030684886331	0.3919960821696149	1.0	0.8671300516102446	2	P06865	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.8270068450529	0.8560030684886331	0.3919960821696149	1.0	0.8671300516102446	2	P06865	1
+GINS subunit, domain A [IPR021151]	0.6900093370681327	0.8554664515865886	0.3922929693166486	1.0	0.8671300516102446	3	Q9Y248,Q9BRT9	2
+BTB/POZ domain [IPR000210]	0.6897749389910486	0.854625232041821	0.392758654401254	1.0	0.8671300516102446	3	Q08380	1
+FAD/NAD(P)-binding domain [IPR023753]	0.56408380703371	0.8257635524624819	0.4089382332316331	1.0	0.8826871797747802	5	O95831	1
+Acyltransferase, C-terminal domain [IPR032098]	0.817983820784075	0.8240627886407123	0.4099038822908118	1.0	0.8826871797747802	2	Q9NUQ2	1
+EH domain-containing protein, N-terminal [IPR031692]	0.8098942128189162	0.7956937311788606	0.4262100713987236	1.0	0.8893228868889124	2	Q9H223	1
+Domain of unknown function DUF5600 [IPR040990]	0.8098942128189162	0.7956937311788606	0.4262100713987236	1.0	0.8893228868889124	2	Q9H223	1
+OTU domain [IPR003323]	0.8061605476042399	0.7826906472287348	0.4338087957953127	1.0	0.8946833036552121	2	Q96FW1	1
+Post-SET domain [IPR003616]	0.5534439510903773	0.7812565142085155	0.4346516407768974	1.0	0.8946833036552121	5	Q9BZ95,O96028	2
+LEM domain [IPR003887]	0.5068667081189296	0.7428784044248079	0.4575553014008686	1.0	0.9043861071447789	6	Q86XL3	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.5049211215377358	0.7341096204860037	0.4628819306276783	1.0	0.9082868956259608	6	O60942,Q9H3S7	2
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.6548397136632462	0.7313806490818786	0.4645466816074317	1.0	0.9082868956259608	3	Q86UV5,P51784	2
+SWAP/Surp [IPR000061]	0.5031152647974979	0.7259827427095699	0.4678493499834544	1.0	0.9082868956259608	6	Q8IWZ8,Q8IWX8,Q15459,O15042,Q8IX01	5
+FERM domain [IPR000299]	0.4810306762207628	0.7254532667545026	0.4681740049847418	1.0	0.9082868956259608	10	O94887	1
+Importin-beta, N-terminal domain [IPR001494]	0.4533304087930549	0.7205688021226393	0.4711748543794303	1.0	0.9082868956259608	14	Q92973,Q96P70	2
+Tim44-like domain [IPR007379]	0.7865588052271295	0.7154448048752748	0.4743342352433308	1.0	0.9095656482264588	2	Q9BRJ2	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.7843808338518997	0.7080862123350398	0.4788917212084578	1.0	0.911911600033858	2	Q96CW5	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.7843808338518997	0.7080862123350398	0.4788917212084578	1.0	0.911911600033858	2	Q96CW5	1
+Guanylate kinase-like domain [IPR008144]	0.4937693550907945	0.7061213727419691	0.4801126614969737	1.0	0.911911600033858	7	Q00013	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4937693550907945	0.7061213727419691	0.4801126614969737	1.0	0.911911600033858	7	Q00013	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7775357809583091	0.6851176336152706	0.4932696937701051	1.0	0.9204007334975708	2	P13674	1
+Extended PHD (ePHD) domain [IPR034732]	0.6373198562993405	0.6714702811686175	0.5019209855967612	1.0	0.9215090161093592	3	Q8IWS0	1
+Rho GTPase-activating protein domain [IPR000198]	0.4907014709702153	0.670463621618978	0.5025622892424568	1.0	0.922053582800804	6	O00459,Q01968	2
+K Homology domain, type 1 [IPR004088]	0.3774089522997128	0.6589160942764363	0.5099496502909799	1.0	0.928433094600101	23	Q96PU8,Q96I24,P61978,Q96AE4,Q92945,P51114,O75525,Q8N9N2,Q07666	9
+Immunoglobulin-like domain [IPR007110]	0.452391880613779	0.6425019964451467	0.5205472934541329	1.0	0.9307914505279448	12	Q08722,P10321,P35613	3
+Aldehyde dehydrogenase domain [IPR015590]	0.4588329181560792	0.6156880565129231	0.5381004214700451	1.0	0.9410100873540524	10	P05091,P51648,O94788	3
+Histone deacetylase interacting domain [IPR013194]	0.7545115121344155	0.6097679233645299	0.5420155528241768	1.0	0.943386781077726	2	O75182	1
+Sin3, C-terminal [IPR031693]	0.7545115121344155	0.6097679233645299	0.5420155528241768	1.0	0.943386781077726	2	O75182	1
+EF-hand, Ca insensitive [IPR014837]	0.6184251478369058	0.6086111011524934	0.542782244500388	1.0	0.943386781077726	3	P12814,Q13813	2
+FERM central domain [IPR019748]	0.4503019560762037	0.6011921358161498	0.5477120217974847	1.0	0.943838179034489	11	O94887	1
+Band 4.1 domain [IPR019749]	0.4503019560762037	0.6011921358161498	0.5477120217974847	1.0	0.943838179034489	11	O94887	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.4556683892314732	0.6002299176532977	0.548353017632552	1.0	0.943838179034489	10	Q9UNK0,O60499,O95721	3
+EH domain [IPR000261]	0.4946266146143888	0.5438279637786483	0.5865598638210225	1.0	0.96675763137476	5	Q9UBC2,Q9H4M9,Q9H223	3
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.4501175616351053	0.5284585446380332	0.597181112688193	1.0	0.9722695371762315	8	Q13546,Q15375,Q9UHY1	3
+AWS domain [IPR006560]	0.5924163506860063	0.5256050354998248	0.5991626573284159	1.0	0.9722695371762315	3	O96028	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7252644679527089	0.5189105314517855	0.6038231333411119	1.0	0.9765579695813026	2	Q9NUQ9	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.4875990758079223	0.5167927036900383	0.6053008739184929	1.0	0.976761339322504	5	P13674,Q32P28,O15460	3
+SET domain [IPR001214]	0.4539043589847139	0.5105371812568953	0.6096751728967613	1.0	0.9771779091739952	6	Q9BZ95,O96028	2
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4267800568347804	0.4848840332638309	0.6277586090261689	1.0	0.9889114370193334	11	Q9Y680,Q9NWM8,Q96AY3	3
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.7137523335407662	0.4848483618535864	0.6277839142428399	1.0	0.9889114370193334	2	P23634	1
+Dynamin, GTPase domain [IPR001401]	0.5764083411142199	0.4768683212581721	0.6334558912403616	1.0	0.9889114370193334	3	P50570,O60313	2
+Lamin tail domain [IPR001322]	0.5745409274821118	0.4713116572338599	0.6374181922660629	1.0	0.9889114370193334	3	Q03252,P02545	2
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.4731791905631204	0.4624970861780877	0.6437248914031506	1.0	0.9889114370193334	5	P48735	1
+I-kappa-kinase-beta NEMO binding domain [IPR022007]	0.7053515868077163	0.460656992715705	0.6450447151726943	1.0	0.9889114370193334	2	O15111	1
+IKBKB, scaffold dimerization domain [IPR041185]	0.7053515868077163	0.460656992715705	0.6450447151726943	1.0	0.9889114370193334	2	O15111	1
+PI31 proteasome regulator,  N-terminal [IPR021625]	0.699751088985687	0.4448551547054202	0.6564244327154909	1.0	0.9889114370193334	2	Q9Y3I1	1
+Peptidase S54, rhomboid domain [IPR022764]	0.6981953951462347	0.4405132110213833	0.6595654460762614	1.0	0.9889114370193334	2	Q6NTF9	1
+ARHGEF1-like, PH domain [IPR041020]	0.6832607342875008	0.3999175926661636	0.6892172141004462	1.0	0.9889114370193334	2	Q92888	1
+Fxr1, tudor domain [IPR041560]	0.546218487394963	0.3906589571557119	0.6960493401641932	1.0	0.9889114370193334	3	P51114,Q06787	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.546218487394963	0.3906589571557119	0.6960493401641932	1.0	0.9889114370193334	3	P51114,Q06787	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.546218487394963	0.3906589571557119	0.6960493401641932	1.0	0.9889114370193334	3	P51114,Q06787	2
+Agenet-like domain [IPR008395]	0.546218487394963	0.3906589571557119	0.6960493401641932	1.0	0.9889114370193334	3	P51114,Q06787	2
+Histidine kinase domain [IPR005467]	0.6761045426260135	0.3811882422662945	0.7030635730106871	1.0	0.9889114370193334	2	Q15118	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.6761045426260135	0.3811882422662945	0.7030635730106871	1.0	0.9889114370193334	2	Q15118	1
+BSD domain [IPR005607]	0.6733042937149978	0.3739913238157877	0.7084107711753989	1.0	0.9889114370193334	2	P32780	1
+MRH domain [IPR044865]	0.5343220343127836	0.3589732934818349	0.7196150682517048	1.0	0.9889114370193334	3	P20645	1
+MIRO domain [IPR020860]	0.6652146857498462	0.3536270204761247	0.7236184217736823	1.0	0.9889114370193334	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.6652146857498462	0.3536270204761247	0.7236184217736823	1.0	0.9889114370193334	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.6652146857498462	0.3536270204761247	0.7236184217736823	1.0	0.9889114370193334	2	Q8IXI1	1
+Putative RNA methylase domain [IPR000241]	0.6521468574984464	0.3221090976477403	0.7473700463668942	1.0	0.9889114370193334	2	Q7Z4G4	1
+Survival motor neuron [IPR010304]	0.6493466085874322	0.3155826414968452	0.7523193149364493	1.0	0.9889114370193334	2	Q16637	1
+Glycosyl transferase, family 1 [IPR001296]	0.5132999750301258	0.3064803654411785	0.7592389271486484	1.0	0.9889114370193334	3	Q2TAA5	1
+EB1, C-terminal [IPR004953]	0.6421904169259516	0.2992768698724227	0.7647288014479146	1.0	0.9889114370193334	2	Q15555	1
+YTH domain [IPR007275]	0.4998443821973259	0.2753769781590227	0.7830266293638615	1.0	0.9889114370193334	3	Q96MU7,Q9H6S0	2
+HDGF-related, PWWP domain [IPR035496]	0.4392901618928993	0.2706829411863513	0.7866348981339748	1.0	0.9889114370193334	4	Q7Z4V5,Q9Y3E1,O75475	3
+Lsm14-like, N-terminal [IPR025609]	0.6232109520846334	0.258690680195603	0.7958739109822259	1.0	0.9889114370193334	2	Q96F86	1
+DFDF domain [IPR025762]	0.6232109520846334	0.258690680195603	0.7958739109822259	1.0	0.9889114370193334	2	Q96F86	1
+FDF domain [IPR019050]	0.6232109520846334	0.258690680195603	0.7958739109822259	1.0	0.9889114370193334	2	Q96F86	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.492063492063501	0.258323036917259	0.7961576085759046	1.0	0.9889114370193334	3	P28340,Q07864	2
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.492063492063501	0.258323036917259	0.7961576085759046	1.0	0.9889114370193334	3	P28340,Q07864	2
+MOSC, N-terminal beta barrel [IPR005303]	0.4911856780377321	0.2564428423312391	0.7976089101566683	1.0	0.9889114370193334	3	Q96EN8	1
+Molybdenum cofactor sulfurase, C-terminal [IPR005302]	0.4911856780377321	0.2564428423312391	0.7976089101566683	1.0	0.9889114370193334	3	Q96EN8	1
+GYF domain [IPR003169]	0.6104542626011246	0.2336388491771189	0.8152653650327994	1.0	0.9889114370193334	2	O95400	1
+Mu homology domain [IPR028565]	0.4221668742216666	0.2275819269960262	0.8199712714518741	1.0	0.9889114370193334	4	Q9Y2T2,Q9BXS5,P48444	3
+Butyrophylin-like, SPRY domain [IPR003879]	0.4165628891656267	0.214316949946806	0.8302999009660987	1.0	0.9889114370193334	4	Q12899,P19474,O15344	3
+SPRY-associated [IPR006574]	0.4165628891656267	0.214316949946806	0.8302999009660987	1.0	0.9889114370193334	4	Q12899,P19474,O15344	3
+Ubiquitin-like domain [IPR000626]	0.3473173874754461	0.211276876690677	0.8326712253932644	1.0	0.9889114370193334	16	P46379	1
+Serine/threonine-protein kinase N, C2 domain [IPR037784]	0.59396390790293	0.2039646337217468	0.8383811361195392	1.0	0.9889114370193334	2	Q16513	1
+Serine/threonine-protein kinase N, first HR1 domain [IPR037313]	0.59396390790293	0.2039646337217468	0.8383811361195392	1.0	0.9889114370193334	2	Q16513	1
+BAT2, N-terminal [IPR009738]	0.4609399315281684	0.1972325395596823	0.843645567826969	1.0	0.9889114370193334	3	P48634,Q9Y520	2
+Dual specificity protein phosphatase domain [IPR020422]	0.459864276657796	0.1953296078908868	0.8451349197180618	1.0	0.9889114370193334	3	O60942	1
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.459864276657796	0.1953296078908868	0.8451349197180618	1.0	0.9889114370193334	3	O60942	1
+G-patch domain [IPR000467]	0.3519923213340191	0.1923215392602883	0.8474903474305397	1.0	0.9889114370193334	14	P98175	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.5852520224019968	0.1895302372058624	0.8496772586808163	1.0	0.9889114370193334	2	Q13641	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.5852520224019968	0.1895302372058624	0.8496772586808163	1.0	0.9889114370193334	2	Q13641	1
+Myb domain [IPR017930]	0.366635694191284	0.1869631284097215	0.851689542407029	1.0	0.9889114370193334	8	Q96KC8	1
+Chromo domain subgroup [IPR017984]	0.4550264550264575	0.1869453649112125	0.8517034700895576	1.0	0.9889114370193334	3	P45973,Q13185	2
+Chromo shadow domain [IPR008251]	0.4550264550264575	0.1869453649112125	0.8517034700895576	1.0	0.9889114370193334	3	P45973,Q13185	2
+Ribosomal protein S10 domain [IPR027486]	0.45440398381575	0.1858873124233519	0.8525331320143716	1.0	0.9889114370193334	3	P60866,Q96GC5	2
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.581518357187311	0.1836070429350606	0.8543217375947036	1.0	0.9889114370193334	2	Q96RL7	1
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.4503579209461571	0.1791252677099482	0.8578393421023942	1.0	0.9889114370193334	3	P20585,P43246	2
+DNA mismatch repair protein MutS, core [IPR007696]	0.4503579209461571	0.1791252677099482	0.8578393421023942	1.0	0.9889114370193334	3	P20585,P43246	2
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.4503579209461571	0.1791252677099482	0.8578393421023942	1.0	0.9889114370193334	3	P20585,P43246	2
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.4503579209461571	0.1791252677099482	0.8578393421023942	1.0	0.9889114370193334	3	P20585,P43246	2
+Dynamin stalk domain [IPR000375]	0.5762289981331736	0.175485178718958	0.860698415744356	1.0	0.9889114370193334	2	P50570	1
+GTPase effector domain [IPR020850]	0.5762289981331736	0.175485178718958	0.860698415744356	1.0	0.9889114370193334	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.5762289981331736	0.175485178718958	0.860698415744356	1.0	0.9889114370193334	2	P50570	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.3592788283117792	0.1614231164859641	0.871760161098255	1.0	0.9889114370193334	8	O60568,P13674,Q32P28	3
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.3592788283117792	0.1614231164859641	0.871760161098255	1.0	0.9889114370193334	8	O60568,P13674,Q32P28	3
+Nucleotidyl transferase domain [IPR005835]	0.427015250544663	0.1440059666171481	0.8854957580704323	1.0	0.9889114370193334	3	Q9NR50,Q9Y5P6	2
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.4257703081232502	0.1423179464485789	0.8868288715952448	1.0	0.9889114370193334	3	O75521,Q5T8D3	2
+Gelsolin-like domain [IPR007123]	0.3532710280373919	0.1397523190225173	0.8888556873817486	1.0	0.9889114370193334	6	O95486,Q15436,Q13045,O95487,Q15437	5
+NET domain [IPR027353]	0.5497822028624818	0.1395492926415594	0.8890161070644387	1.0	0.9889114370193334	2	O60885	1
+Brdt, bromodomain, repeat II [IPR043509]	0.5497822028624818	0.1395492926415594	0.8890161070644387	1.0	0.9889114370193334	2	O60885	1
+Brdt, bromodomain, repeat I [IPR043508]	0.5497822028624818	0.1395492926415594	0.8890161070644387	1.0	0.9889114370193334	2	O60885	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.3792029887920277	0.1370935103220566	0.8909568820493337	1.0	0.9889114370193334	4	O60749,Q9Y5X3,Q13596	3
+Histone deacetylase domain [IPR023801]	0.5457373988799079	0.1347258421604467	0.8928286403761365	1.0	0.9889114370193334	2	Q13547	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.4167444755680025	0.1306311954472464	0.8960670637787711	1.0	0.9889114370193334	3	P61289,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.4167444755680025	0.1306311954472464	0.8960670637787711	1.0	0.9889114370193334	3	P61289,Q9UL46	2
+Methyl-CpG DNA binding [IPR001739]	0.3711083437110811	0.123003007937671	0.9021047160667486	1.0	0.9889114370193334	4	Q15047,O95983,Q9UIF9	3
+Ubiquitin-associated domain [IPR015940]	0.3417987925193805	0.1225181786089587	0.9024886499986796	1.0	0.9889114370193334	12	Q14157,Q9NRR5,P54725	3
+UAS [IPR006577]	0.524579962663344	0.1122738307918094	0.9106062905942802	1.0	0.9889114370193334	2	Q96CS3	1
+Translation initiation factor IF- 2, domain 3 [IPR023115]	0.5208462974486668	0.1087795523668323	0.9133773424105268	1.0	0.9889114370193334	2	P46199	1
+Zinc finger, UBP-type [IPR001607]	0.3611457036114547	0.1069635356186056	0.914817908104191	1.0	0.9889114370193334	4	P45974,Q9UPT9,Q8TEY7	3
+SAP domain [IPR003034]	0.3343740243521618	0.1028095083010403	0.918114158723812	1.0	0.9889114370193334	13	Q00839,Q13435,P82979,Q14151,Q15424,P35659,P12956,Q8IX12,Q1KMD3,Q9UKV3,Q9BUJ2,O75925	12
+Sec23/Sec24, trunk domain [IPR006896]	0.353161009031457	0.1024805788421713	0.9183752275194612	1.0	0.9889114370193334	5	O95486,O95487,Q15436,Q15437	4
+Sec23/Sec24, helical domain [IPR006900]	0.353161009031457	0.1024805788421713	0.9183752275194612	1.0	0.9889114370193334	5	O95486,O95487,Q15436,Q15437	4
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.353161009031457	0.1024805788421713	0.9183752275194612	1.0	0.9889114370193334	5	O95486,O95487,Q15436,Q15437	4
+Sec23/Sec24 beta-sandwich [IPR012990]	0.353161009031457	0.1024805788421713	0.9183752275194612	1.0	0.9889114370193334	5	O95486,O95487,Q15436,Q15437	4
+Exportin-2, central domain [IPR013713]	0.3893303139548041	0.1008902031298058	0.9196376201950148	1.0	0.9889114370193334	3	O15397	1
+PWWP domain [IPR000313]	0.3390776231739445	0.0999214392922537	0.920406695437012	1.0	0.9889114370193334	10	Q7Z4V5,O96028	2
+Glutamine amidotransferase type 2 domain [IPR017932]	0.387799564270154	0.0994742557536706	0.9207617274347556	1.0	0.9889114370193334	3	P08243,Q06203	2
+Peptidase M41 [IPR000642]	0.5090230242688322	0.0985928554699925	0.92146154289145	1.0	0.9889114370193334	2	Q96TA2	1
+Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]	0.5084007467330517	0.0980927273450651	0.9218586624141744	1.0	0.9889114370193334	2	Q9H1B7	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.4978220286247689	0.0901189876295621	0.9281926606665368	1.0	0.9889114370193334	2	P51784	1
+SGS domain [IPR007699]	0.4943995021779798	0.0877468581760293	0.9300778757889756	1.0	0.9889114370193334	2	Q9HB71	1
+AARP2CN [IPR012948]	0.4928438083385187	0.0867010945053989	0.9309091064060622	1.0	0.9889114370193334	2	Q14692	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.4928438083385187	0.0867010945053989	0.9309091064060622	1.0	0.9889114370193334	2	Q14692	1
+Bms1/Tsr1-type G domain [IPR030387]	0.4928438083385187	0.0867010945053989	0.9309091064060622	1.0	0.9889114370193334	2	Q14692	1
+PABP, RNA recognition motif 2 [IPR045305]	0.4915992532669663	0.0858788997322234	0.9315626851064832	1.0	0.9889114370193334	2	Q13310	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.490354698195403	0.0850694035369626	0.9322062145478692	1.0	0.9889114370193334	2	P49841	1
+Exosome complex component, N-terminal domain [IPR025721]	0.4884878655880534	0.0838787335946288	0.9331528480974336	1.0	0.9889114370193334	2	Q9Y3B2	1
+BAG domain [IPR003103]	0.364510029180582	0.0808789433874882	0.9355382258382824	1.0	0.9889114370193334	3	O95429	1
+Myosin tail [IPR002928]	0.3412204234122019	0.0791393351244953	0.936921796706164	1.0	0.9889114370193334	4	Q92614,Q7Z406,P35580	3
+v-SNARE, coiled-coil homology domain [IPR042855]	0.360099595393719	0.0779460801945458	0.9378709441910174	1.0	0.9889114370193334	3	P51809,O75396	2
+Longin domain [IPR010908]	0.360099595393719	0.0779460801945458	0.9378709441910174	1.0	0.9889114370193334	3	P51809,O75396	2
+Sec24-like, trunk domain [IPR041742]	0.3529411764705862	0.0735548295324627	0.941364614535292	1.0	0.9889114370193334	3	O95486,O95487	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.351847561318927	0.0729229091358904	0.9418674636207836	1.0	0.9889114370193334	3	P21912	1
+K Homology domain [IPR004087]	0.290098626851057	0.0694390409908835	0.944640153684271	1.0	0.9889114370193334	22	Q96PU8,Q96I24,P61978,Q96AE4,Q92945,O75525,Q07666	7
+p21 activated kinase binding domain [IPR033923]	0.4595519601742415	0.0687667083215977	0.9451753182433034	1.0	0.9889114370193334	2	Q13153	1
+CRIB domain [IPR000095]	0.4595519601742415	0.0687667083215977	0.9451753182433034	1.0	0.9889114370193334	2	Q13153	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.3309464508094621	0.0669467180924041	0.946624120775988	1.0	0.9889114370193334	4	Q92974,O75116,Q9H0H5	3
+Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]	0.4467952706907348	0.0638715796609148	0.9490724822023956	1.0	0.9889114370193334	2	Q8WVX9	1
+Fatty acyl-CoA reductase, C-terminal [IPR033640]	0.4467952706907348	0.0638715796609148	0.9490724822023956	1.0	0.9889114370193334	2	Q8WVX9	1
+Sec63 domain [IPR004179]	0.330316755068946	0.0624174460032702	0.9502304021464738	1.0	0.9889114370193334	3	Q9UGP8	1
+Clp ATPase, C-terminal [IPR019489]	0.4405724953329178	0.0618199972470004	0.9507061784443476	1.0	0.9889114370193334	2	Q9H078	1
+tRNA synthetases class I, catalytic domain [IPR032678]	0.4393279402613513	0.0614342961940136	0.9510133395192216	1.0	0.9889114370193334	2	Q9HA77	1
+Ribosomal protein L2, C-terminal [IPR022669]	0.4206596141879274	0.0565403719630221	0.9549113347710498	1.0	0.9889114370193334	2	P62917	1
+Ribosomal Proteins L2, RNA binding domain [IPR022666]	0.4206596141879274	0.0565403719630221	0.9549113347710498	1.0	0.9889114370193334	2	P62917	1
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.3285310219542345	0.0554563871686728	0.9557748744465516	1.0	0.9889114370193334	5	Q15375	1
+GCF, C-terminal [IPR022783]	0.3081232492997159	0.05493015450156	0.9561941083201704	1.0	0.9889114370193334	3	Q9UBB9,P16383	2
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.4057249533291825	0.0536682425099432	0.9571994851277728	1.0	0.9889114370193334	2	P12956	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.4057249533291825	0.0536682425099432	0.9571994851277728	1.0	0.9889114370193334	2	P12956	1
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.4057249533291825	0.0536682425099432	0.9571994851277728	1.0	0.9889114370193334	2	P12956	1
+NUC153 [IPR012580]	0.3967019290603605	0.0523024552652407	0.9582876969779172	1.0	0.9889114370193334	2	Q9BSC4	1
+Sorting nexin, N-terminal [IPR005329]	0.3870566272557604	0.0511022601704156	0.959244034992388	1.0	0.9889114370193334	2	O60749	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.3771001866832555	0.0501045225292042	0.9600390958097612	1.0	0.9889114370193334	2	P10644	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	0.9889114370193334	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	0.9889114370193334	2	P30876	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	0.9889114370193334	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	0.9889114370193334	2	P30876	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.3690105787181092	0.0494475392101879	0.9605626436603804	1.0	0.9889114370193334	2	P30876	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.3135118306351158	0.0494288871483101	0.9605775076766304	1.0	0.9889114370193334	4	Q4J6C6,Q86TI2,P13798	3
+Pre-SET domain [IPR007728]	0.3671437461107646	0.049313236891582	0.9606696708384652	1.0	0.9889114370193334	2	Q15047	1
+SMARCC, C-terminal [IPR032451]	0.349408836341007	0.0483086954181443	0.96147022470497	1.0	0.9889114370193334	2	Q8TAQ2	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.349408836341007	0.0483086954181443	0.96147022470497	1.0	0.9889114370193334	2	Q8TAQ2	1
+SMARCC, N-terminal [IPR032450]	0.349408836341007	0.0483086954181443	0.96147022470497	1.0	0.9889114370193334	2	Q8TAQ2	1
+NIPSNAP [IPR012577]	0.3111387678904754	0.0472750567411379	0.9622940076864764	1.0	0.9889114370193334	2	O75323	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.3213144917567588	0.0433778628748318	0.9654003239548988	1.0	0.9913419833318058	9	O15254,Q15067	2
+GTP binding domain [IPR006073]	0.315426881823151	0.0313100878816641	0.975022245387242	1.0	1.0	13	Q969Y2,Q9NTK5	2
+Zinc finger C2H2-type [IPR013087]	0.2907260678641428	0.0167150010976738	0.9866639796878448	1.0	1.0	20	P52756,Q9ULV3,P98175	3
+SANT domain [IPR017884]	0.3087505208802388	0.0064490682727243	0.9948544236614874	1.0	1.0	10	Q96KC8	1
+Myosin, N-terminal, SH3-like [IPR004009]	0.2911865462472777	0.0034515071745463	0.9972461011817512	1.0	1.0	5	Q92614,Q7Z406,P35580,P35579	4

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase [IPR001757]", "1": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:65874f22ae96e2dbcff47407678ecb125b6be6ed73f7281c21eb5f494f6877e5
+size 215877