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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Sphingolipid metabolism 0.7978921413853117 3.668294203781457 0.0002441741193832 0.2862664987543761 0.337204458868293 25 O43681,O95470,P07602,Q06136,Q9NRA0,Q16739,Q96G23,P04062,O15269,P10619,P51648,P16278,Q9NZJ7,Q13510,P17900 15
Ion channel transport 0.7360283232716138 3.44587185036619 0.0005692202252403 0.5444805878920899 0.3930465655284332 26 Q9NQ11,Q15904,P20020,P51790,P51798,P51797,Q9C0H2,Q93050,Q9Y487,P16615,P27105,P05023,Q9HD20 13
Mitochondrial protein import 0.7102738328254924 3.1666703611023364 0.0015419499813342 0.8812905482540353 0.5868633552263306 33 Q99595,Q9Y5J9,Q10713,Q9NS69,Q5JRX3,O14925,Q8N4H5,P21796,Q9UJS0,O60830,O43615,P12236,Q15388,O96008,P12235,Q9Y512,O75746,O75431,Q13505 19
Glycerophospholipid biosynthesis 0.6940786303995193 3.13821155370121 0.0016998214488814 0.9045784476604716 0.5868633552263306 28 Q6P1A2,P48651,Q9UG56,Q9NPH0,Q53H12,Q9Y6K0,Q8IV08,O15228,Q8NF37,Q9NQZ5,Q9HCL2,Q96N66,Q8WWI5 13
Slc mediated transmembrane transport 0.7727843463290787 2.973883550109607 0.0029405664768089 0.98286967066466 0.6831787568873587 21 P12235,Q96QD8,Q9Y6M7,P55011,P35613,P05141,Q8TB61,P30825,Q15043,Q9UBX3,Q70HW3,Q9H936,P53985,P12236,P08195,Q8WWI5 16
Glycosphingolipid metabolism 0.7978010958597003 2.553000742672207 0.0106799268510864 0.999999636796764 0.7179929107061902 15 O43681,P07602,Q16739,P04062,P10619,P16278,Q9NZJ7,Q13510,P17900 9
Sphingolipid de novo biosynthesis 0.8415452077321206 2.45462055441003 0.0141033366815703 0.9999999969719784 0.7179929107061902 10 O95470,Q06136,Q9NRA0,Q96G23,P51648 5
Transport of vitamins nucleosides and related molecules 0.8571413432829158 2.3877298572259864 0.0169527978747756 0.999999999944383 0.7179929107061902 7 P12235,P12236,Q8TB61 3
Cristae formation 0.6962780197808625 2.3298764670069048 0.0198126811437424 0.999999999999005 0.7179929107061902 19 P24539,P56385,Q9Y512,Q6UXV4,O75964,Q5XKP0,Q16891,O75431,Q9BUR5,Q13505,Q9NX63 11
Phospholipid metabolism 0.6034901005708178 2.3148431302038204 0.0206215185922966 0.9999999999996818 0.7179929107061902 40 Q6P1A2,P48651,Q9UG56,Q9NPH0,Q53H12,Q9Y6K0,Q8IV08,P61106,O15228,Q10713,Q8NF37,Q9NTJ5,Q9NQZ5,Q9BTU6,Q9HCL2,Q96N66,Q8WWI5,Q8NCC3 18
Ion transport by p type atpases 0.8086949294848799 2.303604266153345 0.0212448681568455 0.999999999999868 0.7179929107061902 10 Q9NQ11,P20020,P16615,P05023,Q9HD20 5
Pink1 prkn mediated mitophagy 0.8182576895877351 2.3004681108025897 0.021421713931103 0.9999999999998972 0.7179929107061902 9 O96008,Q8IWA4,Q9NS69,O95140,Q8N4H5,P21796 6
Mitophagy 0.774325495503947 2.2442384168870393 0.0248170654831003 0.9999999999999992 0.7179929107061902 12 O96008,Q8IWA4,Q9NS69,O95140,Q8N4H5,P21796 6
Synthesis of pc 0.8302932054774015 2.23435240218555 0.0254598949088638 0.9999999999999996 0.7179929107061902 6 Q8WWI5,Q8NF37,Q9NQZ5 3
Rhog gtpase cycle 0.5768069027613125 2.2328525805720285 0.0255586675280088 0.9999999999999996 0.7179929107061902 33 P49257,O95202,P42167,P42166,Q96JJ3,Q86XL3,O15173,Q14739 8
Mitochondrial calcium ion transport 0.7310966508586882 2.2089748705180425 0.0271763888442169 1.0 0.7179929107061902 15 Q8IYU8,O95202,Q9Y4W6,Q9UJZ1,Q10713,P45880,Q99623,Q9BPX6,P35232,P21796,Q9Y277 11
Stimuli sensing channels 0.8036911178143484 2.1916991959915184 0.0284012338397081 1.0 0.7179929107061902 8 P51798,P51790,P51797,Q9C0H2,P27105 5
Protein localization 0.6467860244088623 2.1795428835689963 0.0292913625699193 1.0 0.7179929107061902 70 O43681,Q99595,Q9Y5J9,Q9NR77,Q10713,Q9Y3D6,Q9NS69,Q5JRX3,O14925,Q8N4H5,P21796,Q6QHF9,Q9UJS0,P39210,O60830,O15228,Q13011,P09601,O43615,P12236,P50402,P14735,Q8NBU5,P46379,Q15388,P51648,O75381,O96008,P12235,Q9Y512,O75746,O00116,O75431,Q13505 34
Glycosaminoglycan metabolism 0.7123070061675395 2.1781213955245375 0.0293970001032337 1.0 0.7179929107061902 16 P54802,Q96L58,O75330,Q8NCH0,P16278,Q7LGA3,Q8TB61,O43505 8
Transport of inorganic cations anions and amino acids oligopeptides 0.7758810182767945 2.149988587581918 0.0315561175164755 1.0 0.7179929107061902 10 Q96QD8,Q9Y6M7,P30825,P55011,Q9UBX3,Q70HW3,Q9H936,P08195 8
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7771771525958987 2.1116234759369905 0.0347187573397544 1.0 0.7179929107061902 9 O43681,P09601,P46379,P51648 4
Synthesis of very long chain fatty acyl coas 0.7844557816064153 2.0672829883484263 0.0387074962744189 1.0 0.7179929107061902 7 Q9P035,Q53GQ0 2
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.8563466134214781 2.040347810494111 0.0413156960335114 1.0 0.7179929107061902 5 P12235,P12236 2
Synthesis of pa 0.7753855417898166 2.0264369186459112 0.0427200309018442 1.0 0.7179929107061902 7 Q8NF37,Q9NPH0,O15228 3
Cholesterol biosynthesis 0.6794074226723704 1.998023472809182 0.0457141153888069 1.0 0.7388203909841676 16 Q15392,O76062,Q16850,Q15800,Q9H2C2,Q14739,P48449,P04035 8
Metabolism of porphyrins 0.7471727182158396 1.9710460229329956 0.0487186118612503 1.0 0.7388203909841676 9 P09601,P30519,P22830 3
Phase i functionalization of compounds 0.6863120387820468 1.9700640694506888 0.0488310281792689 1.0 0.7388203909841676 15 O43169,P16435,Q16850,Q6QHF9 4
Class i peroxisomal membrane protein import 0.7536924260541954 1.96300113012527 0.0496460427187357 1.0 0.7388203909841676 8 Q8NBU5,O43808,Q9NR77,Q9Y3D6,P51648,O75381 6
Heparan sulfate heparin hs gag metabolism 0.7550482848179653 1.934165073186134 0.0530928351741399 1.0 0.7388203909841676 7 P54802,Q7LGA3,P16278 3
Peptide ligand binding receptors 0.7392397607987822 1.933507403901332 0.0531737218892023 1.0 0.7388203909841676 9 Q9NZJ7,P22466,P42892,P07602 4
Class a 1 rhodopsin like receptors 0.7392397607987822 1.933507403901332 0.0531737218892023 1.0 0.7388203909841676 9 Q9NZJ7,P07602,P22466,P42892 4
Recruitment of mitotic centrosome proteins and complexes 0.5208895235518369 1.878164381556492 0.0603586811177003 1.0 0.7790218562948057 29 P41208,O75935,O94927,Q13561,P04350,Q15691,Q96CS2,Q9BSJ2,P62258,P06493,Q68CZ6,Q9H6D7,P07437,O43805,O95684,P68371,Q14203 17
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7450540987874767 1.8576050574897267 0.0632251198028248 1.0 0.7796156996866997 6 Q16850,Q9NR77 2
Rab geranylgeranylation 0.6027705885371537 1.85420637808633 0.063709639958549 1.0 0.7796156996866997 20 P53611,P62820,P51151,Q969Q5,Q92696,P61106,P61026,P61020,P61019 9
Selective autophagy 0.5151452796039059 1.8508654727447624 0.0641889090467553 1.0 0.7796156996866997 28 O96008,P08670,Q8IWA4,Q9NS69,O95140,Q8N4H5,P21796 7
Respiratory electron transport 0.5625522889875059 1.8395159821999525 0.0658393293757577 1.0 0.7804778761815139 51 O14949,O43676,Q9Y6M9,O43819,O14548,Q9UDW1,P00403,Q9BQ95,P20674,P21912,O95298,P22695,O75880,Q9P0J0,Q8IUX1,P13073,Q16134,Q9NPL8,Q86Y39 19
Metabolism of steroid hormones 0.733307190889416 1.8344865882293175 0.0665817968484923 1.0 0.7804778761815139 7 O95772,Q53GQ0,Q14849 3
Intra golgi traffic 0.6797911883682447 1.8202630588826736 0.0687189541514934 1.0 0.7804778761815139 13 O95249,Q16706,P83436,Q14746,O60476,O00461 6
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5750134764300492 1.7971401252887822 0.0723133770306903 1.0 0.7804778761815139 60 O14949,O43676,Q9Y6M9,P06576,O43819,O00483,O75964,O14548,Q9UDW1,P24539,P56385,O96000,P03915,O95168,P00403,Q9BQ95,P20674,P21912,O95298,P56134,P22695,O75880,P08574,Q9P0J0,Q8IUX1,P13073,Q16134,Q9NPL8,O75306,Q86Y39 30
Processing of smdt1 0.7024091339314728 1.7960083014066592 0.072493196784187 1.0 0.7804778761815139 10 Q8IYU8,Q9Y4W6,Q9UJZ1,Q10713,Q99623,Q9BPX6,P35232 7
Mitochondrial biogenesis 0.5076574745539236 1.7587066414801025 0.0786273487504958 1.0 0.803969862595947 30 P24539,P56385,Q9Y512,Q6UXV4,O75964,Q5XKP0,Q16891,O75431,Q9BUR5,Q13505,Q9NX63 11
Rac2 gtpase cycle 0.510501858918872 1.747059927802666 0.080626943448532 1.0 0.803969862595947 32 P49257,Q9Y512,P42167,P42166,Q86XL3,Q13505,O15173,Q14739 8
Synaptic adhesion like molecules 0.7203333978692038 1.745367410201371 0.0809209347580279 1.0 0.803969862595947 6 O75955,O95197,P41440 3
Gpcr ligand binding 0.6718771433874213 1.7297189512567832 0.0836805010789225 1.0 0.8078872993915477 12 P07602,P22466,Q9BYT8,Q9Y3E5,Q9NRV9,P42892,Q9NZJ7 7
Miscellaneous transport and binding events 0.7165163081193581 1.7279230446040177 0.0840020221770694 1.0 0.8078872993915477 6 Q9UEY8,Q9H0U3,Q8N4V1,Q9UNS2,Q8IWT6 5
Rhod gtpase cycle 0.493598928341407 1.7172387443542452 0.0859355591092916 1.0 0.8078872993915477 26 P49257,Q9UEY8,Q9Y6M7,Q658P3,P42167,P42166,Q14739,O15173,Q9H0H5,P50402 10
Aurka activation by tpx2 0.500265034275593 1.7009910740293468 0.088944663305202 1.0 0.8078872993915477 30 P41208,O75935,O94927,Q13561,P04350,O75330,Q15691,Q96CS2,P62258,P06493,Q68CZ6,Q9H6D7,P07437,O43805,O95684,P68371,Q14203 17
Anchoring of the basal body to the plasma membrane 0.4977844590548486 1.6815527771208496 0.0926555942009847 1.0 0.8078872993915477 30 P41208,O75935,O94927,Q13561,P04350,Q15691,Q96CS2,P62258,P06493,Q68CZ6,Q9H6D7,P07437,O43805,O95684,P68371,Q14203 16
Formation of atp by chemiosmotic coupling 0.6793837272163499 1.6454316256832515 0.099880832124775 1.0 0.8078872993915477 9 P24539,O75964 2
O linked glycosylation 0.8252037205307785 1.627903756834954 0.1035452947084025 1.0 0.8078872993915477 4 Q10472 1
O linked glycosylation of mucins 0.8252037205307787 1.627903756834954 0.1035452947084025 1.0 0.8078872993915477 4 Q10472 1
Basigin interactions 0.681914414407147 1.5684688544758438 0.1167717530673035 1.0 0.8639474135804665 6 P08195,P35613 2
Complex i biogenesis 0.4808994727828552 1.565351449019846 0.1175005257589969 1.0 0.8639474135804665 29 O43676,O96000,P03915,Q9P0J0,Q8IUX1,Q9Y6M9,Q9BQ95,Q9NPL8,O75306,Q86Y39,O95298 11
Platelet calcium homeostasis 0.8096024254466749 1.5647683977150084 0.1176372242315477 1.0 0.8639474135804665 4 P20020,P16615 2
Reduction of cytosolic ca levels 0.8096024254466749 1.5647683977150084 0.1176372242315477 1.0 0.8639474135804665 4 P20020,P16615 2
Transport of bile salts and organic acids metal ions and amine compounds 0.8030513176144245 1.538186907037946 0.1240029213639906 1.0 0.8720373423329614 4 Q15043,P35613,Q8WWI5 3
Diseases of carbohydrate metabolism 0.6639574414298643 1.5380620360466506 0.124033447289461 1.0 0.8720373423329614 8 P54802,P15586,P10253,P16278 4
Ire1alpha activates chaperones 0.5397046721905825 1.5309163627912623 0.1257900646619243 1.0 0.8720373423329614 21 Q9Y5M8,O14773,P43307,Q9NWM8,Q8N6T3,O95070 6
Pregnenolone biosynthesis 0.7347554599651038 1.523101654018221 0.1277332751155111 1.0 0.8720373423329614 5 O95772,Q14849 2
Amino acid transport across the plasma membrane 0.7954230235783636 1.5071864171144975 0.13176288086939 1.0 0.8720373423329614 4 P08195,P30825,Q96QD8 3
Miro gtpase cycle 0.7931109417997984 1.497780677368956 0.1341902426772581 1.0 0.8720373423329614 4 Q8IXI1,Q8IWA4 2
Attachment of gpi anchor to upar 0.7273673257024007 1.4909581332871673 0.1359724871576131 1.0 0.8720373423329614 5 Q96S52,Q92643,O43292,Q9H490 4
Tp53 regulates metabolic genes 0.4787834429769267 1.4808248943885056 0.1386532409483289 1.0 0.8720373423329614 33 P31751,Q04917,Q9HCE1,P00390,O43819,P13073,Q7LG56,P62258,O00483,P00403,Q9Y2Q5,P20674,O14548,O75880,P10606,P63104 16
Cardiac conduction 0.6313845092005517 1.4779943164239566 0.1394092995218894 1.0 0.8720373423329614 11 P05023,P20020,P16615 3
Ion homeostasis 0.6313845092005517 1.4779943164239566 0.1394092995218894 1.0 0.8720373423329614 11 P05023,P20020,P16615 3
Recruitment of numa to mitotic centrosomes 0.4783757572832239 1.4775835039838168 0.1395192923741719 1.0 0.8720373423329614 33 Q96CS2,P62258,P07437,Q14203,P41208,Q9BUF5,O75935,Q13561,P53350,Q68CZ6,Q15691,P06493,Q9H6D7,P68371,O94927,Q9BVA1,P04350,Q9BSJ2,O43805,O95684 20
Iron uptake and transport 0.5655063008423402 1.4695372993672453 0.1416871126522179 1.0 0.8720373423329614 18 Q15904,Q93050,P09601,Q9Y487,P30519 5
Cargo concentration in the er 0.6137483294068546 1.4688481220603944 0.1418739883423194 1.0 0.8720373423329614 13 P49257,Q15363,Q9HCU5,P49755,O75396,Q9Y6B6,Q96PC5 7
Heme degradation 0.9179599670097108 1.4602610802832574 0.1442183341082641 1.0 0.8720373423329614 3 P09601 1
Activation of ampk downstream of nmdars 0.716614637530349 1.4440622609673022 0.1487214625693453 1.0 0.8720373423329614 5 Q9BUF5,Q9BVA1,P68371,P04350 4
Transport of connexons to the plasma membrane 0.716614637530349 1.4440622609673022 0.1487214625693453 1.0 0.8720373423329614 5 Q9BUF5,Q9BVA1,P68371,P04350 4
Gap junction assembly 0.716614637530349 1.4440622609673022 0.1487214625693453 1.0 0.8720373423329614 5 Q9BUF5,Q9BVA1,P68371,P04350 4
Rac3 gtpase cycle 0.4665045631109758 1.433489203714153 0.1517180820825727 1.0 0.8762389935488901 30 P49257,O75962,Q9H0H5,Q9UQB8,P42167,P42166,P02786,Q15758,O15498,O15173,Q14739,P50402 12
Diseases associated with glycosaminoglycan metabolism 0.7046252306816245 1.391627554070799 0.1640352105206055 1.0 0.9081898450351604 5 Q8NCH0 1
Autophagy 0.4835947941357956 1.354959100936353 0.1754305880275548 1.0 0.9137045031360114 43 O96008,Q9UQN3,P08670,Q8IWA4,Q9NS69,O95140,Q8N4H5,P21796,P13473 9
Arachidonic acid metabolism 0.6233870340315842 1.3406256821426137 0.1800420146010966 1.0 0.9137045031360114 8 Q15165,Q9H7Z7 2
Post translational modification synthesis of gpi anchored proteins 0.6307019857516933 1.328605637016364 0.1839781113292391 1.0 0.9137045031360114 6 Q96S52,Q92643,O43292,Q9H490 4
Retrograde transport at the trans golgi network 0.5705422789275743 1.3243351976373403 0.185391745849005 1.0 0.9137045031360114 15 O43493,O60499,P20645,Q14746 4
Mucopolysaccharidoses 0.7496874567269965 1.3204672964651674 0.1866790479221549 1.0 0.9137045031360114 4 P54802,P16278 2
Heme biosynthesis 0.6277876013609492 1.3148414220233746 0.1885632030367583 1.0 0.9137045031360114 6 Q7KZN9,P22830 2
Cytochrome p450 arranged by substrate type 0.8774263934142432 1.3022543960557222 0.1928294355939481 1.0 0.9182670708801464 3 Q16850 1
Chondroitin sulfate dermatan sulfate metabolism 0.743435654316138 1.2948662764024874 0.1953663638281351 1.0 0.920650700719787 4 Q8NCH0 1
Acyl chain remodelling of pc 0.8708886361450308 1.276792567551115 0.2016754902355382 1.0 0.9297719113890166 3 Q8NF37 1
Transferrin endocytosis and recycling 0.5898846439281104 1.26219436976288 0.2068788541679143 1.0 0.93962096409051 11 Q93050,Q9Y487,Q15904 3
Keratan sulfate keratin metabolism 0.6730281275430939 1.2528642956762477 0.2102550976656862 1.0 0.9427347073906258 5 P16278,O43505 2
Copi dependent golgi to er retrograde traffic 0.4722042301231179 1.2326377801100468 0.2177109349362327 1.0 0.9552205911008284 45 O14579,Q9BVA1,Q15363,P62820,Q9P2W9,Q9BVK6,Q9Y3B3,P24390,P33176,Q9H0U4,P49755,O75396,Q12981,P68371,O15260,Q8N6T3,Q9H0H5 17
Abc transporter disorders 0.4701502778021431 1.2321806828871953 0.2178815975356705 1.0 0.9552205911008284 44 P60900,P28074,Q9UL46,O94905,P49721,P62191,O00231,O75477,Q9NUN5,Q92530,P28072,Q9UBV2,P61289,Q9GZP9,Q9BUN8 15
Diseases of glycosylation 0.5268525443813583 1.230129124919909 0.2186487551744051 1.0 0.9555504142273846 18 Q9BT22,P10619,Q8NCH0,P16278,O43505 5
Insulin receptor recycling 0.5949043871579747 1.2262817230587109 0.220092676793312 1.0 0.9558112787785028 9 Q93050,Q9Y487 2
Carboxyterminal post translational modifications of tubulin 0.6082400845354188 1.2222829391195935 0.221600648739817 1.0 0.9563452997177728 6 Q9BUF5,Q9BVA1,P68371,P04350 4
Apoptotic factor mediated response 0.6597821177091264 1.1945290428828883 0.2322710869451305 1.0 0.9637584418521796 5 O60443 1
Vitamin d calciferol metabolism 0.9483714483714514 1.1901533260248038 0.2339861341301232 1.0 0.9637584418521796 2 P04062 1
Ros and rns production in phagocytes 0.5921556970746238 1.1870381601773166 0.2352125687614608 1.0 0.9637584418521796 8 Q93050 1
Interleukin 4 and interleukin 13 signaling 0.5687327123548997 1.1853475682438812 0.2358800531108158 1.0 0.9637584418521796 12 P08670,P09601 2
Integrin cell surface interactions 0.7100590620499281 1.1581377536216673 0.2468078253490946 1.0 0.9683000193383514 4 P35613 1
Wax and plasmalogen biosynthesis 0.7066574202496535 1.1442131810799223 0.2525352380001679 1.0 0.9799765177667104 4 O00116,Q6IAN0,O15228 3
Rhoa gtpase cycle 0.4516466311926617 1.116097902936457 0.2643802297148494 1.0 0.9989270270776696 42 P49257,O75955,Q15904,P51572,P42167,P42166,Q8NBN3,P27105,P41440,O15173,Q14254,P30519,Q14739 13
Pre notch processing in golgi 0.8259965337954811 1.1026547496998274 0.2701771244940052 1.0 1.0 3 P16615,Q15363 2
Thrombin signalling through proteinase activated receptors pars 0.6378772112382934 1.098006609588299 0.2722016031191518 1.0 1.0 5 P28482,P29992,P63218,Q9UBI6 4
Pyroptosis 0.5712976897198261 1.0840075415455916 0.2783614550541675 1.0 1.0 8 O60443,Q9UQN3 2
Hs gag degradation 0.8163284218369411 1.0654070874266448 0.2866917508985311 1.0 1.0 3 P16278 1
Tp53 regulates transcription of cell death genes 0.5728719870861093 1.054139214710513 0.2918191846297904 1.0 1.0 6 Q658P3,P53611 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5697243901144894 1.039161557254263 0.2987296059762963 1.0 1.0 6 P10321,Q5KU26,P78310,P04439 4
Copii mediated vesicle transport 0.4129787985430101 1.0323315135215054 0.3019168430570622 1.0 1.0 28 P49257,Q15363,P62820,O15498,Q9HCU5,Q9H0U4,P49755,O75396,Q9Y6B6,Q9Y296,Q12907 11
Sulfur amino acid metabolism 0.5596091907447381 1.0262153781564327 0.3047900742496472 1.0 1.0 8 Q9UBX3,Q13126 2
Regulated necrosis 0.4887802272101912 0.9915344327371572 0.3214246875761357 1.0 1.0 18 O75955,O60443,Q9UQN3,O43633,Q16543,P41440,Q14254 7
Unwinding of dna 0.5401820492043115 0.9739681538180552 0.3300723517696502 1.0 1.0 10 Q9BRX5,Q9BRT9,P33991 3
Synthesis of pe 0.8853083853083848 0.9545960563880054 0.339782012243162 1.0 1.0 2 Q9UG56 1
Er quality control compartment erqc 0.6598843126699423 0.9536236742133852 0.3402741677499403 1.0 1.0 4 Q9GZP9,Q9UKV5 2
Response to elevated platelet cytosolic ca2 0.4094447064031645 0.953035895515254 0.3405718838416556 1.0 1.0 31 P07602,O94919,Q92520,Q8NBX0,Q9NZJ7,Q9NUQ9,P13473 7
Hur elavl1 binds and stabilizes mrna 0.6042072850924958 0.9500222791903784 0.3421009322765909 1.0 1.0 5 Q01105 1
Biological oxidations 0.432859921530578 0.9490944743257164 0.3425725645140314 1.0 1.0 43 P16435,P21964,O43169,Q16850,P07099,Q9NUJ1,Q8TB61,Q6QHF9 8
Golgi associated vesicle biogenesis 0.4004893407091301 0.946366828883955 0.343961518149336 1.0 1.0 27 P55327,Q9BXS5,Q9Y5X3,O43493,P50570,P51809,Q14789,O60749,O75976 9
Wnt ligand biogenesis and trafficking 0.5475343666729596 0.933680376158036 0.3504687905999253 1.0 1.0 6 Q9UBQ0,Q5T9L3 2
Chaperone mediated autophagy 0.5407131867628743 0.9156590611732462 0.3598457435437141 1.0 1.0 7 P13473 1
Energy dependent regulation of mtor by lkb1 ampk 0.6504476411828042 0.915502754652584 0.3599277570056032 1.0 1.0 4 Q9Y376,Q9Y2Q5 2
Defective cftr causes cystic fibrosis 0.4253405985366208 0.8885536195771288 0.3742430268103467 1.0 1.0 43 P60900,P28074,Q9UL46,O94905,P49721,P62191,O00231,O75477,Q92530,P28072,Q9UBV2,P61289,Q9GZP9,Q9BUN8 14
Cytoprotection by hmox1 0.4608283166024882 0.8842933274002746 0.3765378893409394 1.0 1.0 62 P28074,Q9UL46,O43819,P49721,P62191,P13073,O00231,P00403,P09601,P20674,O14548,P28072,O75880,P61289,P30519,Q8TCT9 16
Regulation of plk1 activity at g2 m transition 0.4065510852774264 0.8800601351665288 0.3788267335152948 1.0 1.0 34 P41208,O75935,O94927,Q13561,P04350,Q15691,Q96CS2,P62258,P06493,Q68CZ6,Q9H6D7,P07437,O43805,O95684,P68371,Q14203 16
Release of apoptotic factors from the mitochondria 0.8610533610533724 0.8663938424450169 0.3862742195329165 1.0 1.0 2 O60443 1
Peroxisomal protein import 0.4320771325855022 0.8632323089842053 0.3880097530984732 1.0 1.0 22 P39210,O15228,Q13011,O00116,O75381,Q6QHF9 6
Cell surface interactions at the vascular wall 0.4947402183283718 0.8493486136447778 0.3956873376194649 1.0 1.0 14 P08195,P35613,Q08722,P53985,Q92896 5
Endosomal vacuolar pathway 0.6315967896454435 0.8398828736334343 0.400974061055334 1.0 1.0 4 P10321 1
Signaling by erbb2 in cancer 0.6314147018030515 0.8391564464948911 0.401381524082615 1.0 1.0 4 P19174,P62993,Q16543 3
Signaling by erbb2 ecd mutants 0.6314147018030515 0.8391564464948911 0.401381524082615 1.0 1.0 4 P19174,P62993,Q16543 3
Metabolism of steroids 0.4249835559210991 0.839052960502246 0.4014395910272208 1.0 1.0 46 Q15392,O76062,O95772,Q16850,P14324,Q53GQ0,Q9H2C2,Q15800,Q14739,P38435,Q14849,P04062,P48449,P04035 14
Copi mediated anterograde transport 0.4337670770123828 0.8329633476090114 0.404865400823633 1.0 1.0 51 O75935,O95249,Q13561,Q15363,P62820,P83436,Q14746,Q9BVK6,Q9UJW0,Q9Y3B3,O14579,P24390,P49755,P68371,Q8N6T3,Q14789 16
Trans golgi network vesicle budding 0.3984464073052861 0.813968287459987 0.4156631184912878 1.0 1.0 34 P55327,Q9BXS5,O43633,Q9Y5X3,O43493,P20645,P50570,P51809,P15586,Q14789,O60749,P02786,O75976 13
Pi metabolism 0.493568453631479 0.8100598892971526 0.4179057559355597 1.0 1.0 13 Q8TBX8,P61106,Q10713,Q9NTJ5,Q9BTU6 5
Growth hormone receptor signaling 0.6212154928473436 0.798609064346964 0.4245171300647716 1.0 1.0 4 P18031,P40763 2
Intra golgi and retrograde golgi to er traffic 0.4869097552615504 0.7827570675730857 0.4337697832320502 1.0 1.0 84 O95249,Q15363,P62820,P20645,O75396,Q8N6T3,O75935,Q13561,P83436,Q9BVK6,P51151,Q9Y3B3,P24390,Q10472,P49755,O00461,Q9H0H5,Q9P2W9,Q14746,Q12981,P68371,O15260,Q9UJW0,O60499,Q15102,O14579,Q16706,O43493,O60476,O15498 30
Organic anion transporters 0.8364518364518561 0.7788924189062884 0.4360430900996968 1.0 1.0 2 Q9UBX3 1
Keratan sulfate degradation 0.6161579554043308 0.7786136398019459 0.4362073418367931 1.0 1.0 4 P16278 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4450661435527362 0.7670426751710585 0.4430561430481297 1.0 1.0 19 Q86YN1,Q9BT22,P10619,P16278 4
N glycan antennae elongation in the medial trans golgi 0.8322938322938317 0.7643314706758819 0.4446697357312361 1.0 1.0 2 P04066 1
Reactions specific to the complex n glycan synthesis pathway 0.8322938322938317 0.7643314706758819 0.4446697357312361 1.0 1.0 2 P04066 1
Sialic acid metabolism 0.5610215431349999 0.7625899847222082 0.4457079593547155 1.0 1.0 5 P10619 1
Abc family proteins mediated transport 0.4222424626042981 0.7563338700104836 0.4494490458910254 1.0 1.0 50 P60900,P28074,Q9UL46,O94905,P08183,P49721,P62191,O00231,O75027,O75477,Q92530,P28070,P28072,Q9UBV2,P61289,Q9GZP9,Q9BUN8 17
Unfolded protein response upr 0.397834830013689 0.7452103434713261 0.4561445708924587 1.0 1.0 38 Q9Y5M8,O14773,P43307,Q9NWM8,Q15024 5
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4749179176834905 0.7381991255769028 0.4603934541776586 1.0 1.0 14 O43493,Q02818 2
Beta oxidation of pristanoyl coa 0.6000408161879193 0.7154581234418435 0.4743260081539462 1.0 1.0 4 O14734,P51659 2
Transport of small molecules 0.578455216895824 0.7151440995603188 0.4745200065408537 1.0 1.0 149 Q8IYU8,Q9H0U3,Q96QD8,Q8WTV0,P62191,P05141,Q8N4V1,P45880,Q10713,P05023,P61289,P21796,P08195,P28074,P51790,Q9UL46,P51797,Q9C0H2,P55011,P35613,O00231,O75027,P09601,Q9UBX3,Q9Y487,P27105,P16615,Q15043,Q70HW3,Q9UNS2,Q99623,Q9BPX6,P53985,Q8TB61,P12236,Q99797,Q9BUN8,Q9NQ11,Q8WWI5,Q15904,P51798,O94905,Q9Y6M7,O75477,Q93050,Q15758,Q4KMQ2,P28072,P20020,P35232,P61421,P30519,P23634,Q9H936,Q9UEY8,P60900,P12235,O95202,P49721,P08183,Q658P3,Q9UBV2,P30825,Q9Y4W6,Q92530,Q9UJZ1,O15118,Q9HD20,Q9GZP9,Q9Y277 70
Interleukin 27 signaling 0.7208082206810749 0.7082241528052677 0.478806069516184 1.0 1.0 3 P27824 1
Interleukin 35 signalling 0.7208082206810749 0.7082241528052677 0.478806069516184 1.0 1.0 3 P27824 1
Synthesis of pips at the golgi membrane 0.4988579831045485 0.7046892628060787 0.4810036347328283 1.0 1.0 6 Q10713,Q9NTJ5 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4860650539618618 0.6973194930264032 0.4856028716201326 1.0 1.0 10 O43681,O60725,P38435 3
Aspartate and asparagine metabolism 0.5436143105525298 0.6884639290839073 0.4911606777113053 1.0 1.0 5 Q9UJS0 1
Proton coupled monocarboxylate transport 0.8024948024948209 0.6622464893437972 0.5078132645371989 1.0 1.0 2 P35613 1
Copi independent golgi to er retrograde traffic 0.3621292448875364 0.6469860426463073 0.5176409767525174 1.0 1.0 26 O75935,Q9BUF5,Q13561,Q9BVA1,P04350,Q10472,P68371,Q14203,Q9UJW0,Q15102 10
Regulation of hmox1 expression and activity 0.3987128429357139 0.6444694190522123 0.5192710818697197 1.0 1.0 45 P28074,Q9UL46,P49721,P62191,O00231,P09601,P28072,P61289,Q8TCT9 9
Cellular response to hypoxia 0.3889775120398707 0.6428644721262935 0.5203120443054039 1.0 1.0 40 P28074,Q9Y241,Q9UL46,P49721,P62191,O00231,P28072,P61289 8
Cilium assembly 0.4168845289783309 0.6403447960669437 0.5219484637406864 1.0 1.0 55 Q96CS2,P62258,Q10713,P07437,Q14203,P41208,Q9BUF5,A6NIH7,Q13561,O75935,P53350,Q68CZ6,Q96KP1,Q15691,P06493,Q9H6D7,P68371,O94927,Q9BVA1,P04350,O43805,O95684,Q9UPT5 23
Signaling by insulin receptor 0.4566932468196385 0.6370601234672159 0.5240856816628563 1.0 1.0 14 Q93050,Q9Y487 2
Adp signalling through p2y purinoceptor 1 0.5795362934029405 0.6365898190496081 0.5243920584888861 1.0 1.0 4 P29992,Q9UBI6 2
The citric acid tca cycle and respiratory electron transport 0.4754630667724457 0.6181162137836655 0.536498735160202 1.0 1.0 90 O14949,O43676,Q9Y6M9,P06576,O43819,O00483,O75964,O14548,Q9UDW1,P21796,P24539,P03915,O96000,P56385,O95563,P35613,O95168,P00403,Q15120,Q9BQ95,P20674,P21912,P53985,O95298,Q13423,P56134,P22695,O75880,P08574,Q9H9P8,Q9P0J0,Q8IUX1,P13073,Q16134,Q9NPL8,O75306,Q86Y39 37
G alpha i signalling events 0.3789014159807154 0.6179370522872428 0.5366168335159658 1.0 1.0 24 P07602,P22466 2
Sealing of the nuclear envelope ne by escrt iii 0.4589561549484211 0.59877470970046 0.5493231292855785 1.0 1.0 12 Q9BUF5,Q9BVA1,Q9UQN3,O43633,P04350,Q13885,P68371 7
Metabolism of polyamines 0.3808987815847989 0.5936394702456153 0.5527532757672255 1.0 1.0 39 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289,Q6QHF9 8
G protein activation 0.6863084922010352 0.5873716056393923 0.5569541594739462 1.0 1.0 3 P29992,Q9UBI6 2
Class b 2 secretin family receptors 0.6863084922010263 0.5873716056393632 0.5569541594739658 1.0 1.0 3 Q9Y3E5,Q9UBI6 2
G beta gamma signalling through pi3kgamma 0.6863084922010262 0.5873716056393625 0.5569541594739662 1.0 1.0 3 P31751,Q9UBI6 2
Downregulation of erbb2 signaling 0.5178126000367071 0.580924771722992 0.561291156148052 1.0 1.0 5 Q16543 1
Fgfr1 mutant receptor activation 0.467976370768557 0.5797561532247012 0.5620790699085418 1.0 1.0 8 O95684,O94905 2
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4290635369138721 0.5784646343914474 0.5629504675193981 1.0 1.0 17 Q9BUF5,Q9BVA1,O15212,P04350,Q99471,Q99832,Q9UHV9,P68371 8
Pyruvate metabolism 0.4495869222091874 0.5722720415002173 0.5671376878122907 1.0 1.0 13 P21796 1
Activated notch1 transmits signal to the nucleus 0.7744282744282884 0.5703650769300695 0.5684301109333714 1.0 1.0 2 Q92542 1
Golgi to er retrograde transport 0.4269032015633465 0.5634773472582096 0.5731098810844888 1.0 1.0 66 O75935,O14579,Q13561,Q15363,P62820,Q9P2W9,Q9BVK6,Q9UJW0,Q9Y3B3,P24390,Q10472,P49755,Q12981,P68371,O15260,Q8N6T3,Q9H0H5 17
Initiation of nuclear envelope ne reformation 0.4245873716496555 0.5519773744239231 0.5809638548795748 1.0 1.0 17 P42167,P42166,Q14739,Q86XL3 4
Signaling by gpcr 0.3780561440171601 0.5408341285809283 0.5886219169318547 1.0 1.0 41 P10644,P31751,P07602,O75962,P22466,Q9Y3E5,Q8NCG7,Q9BYT8,Q8N2K0,P52292,Q9NRV9,P42892,Q9NZJ7,P51812 14
Nuclear signaling by erbb4 0.6682842287694778 0.526870679157923 0.5982833965321404 1.0 1.0 3 P61201,Q92542 2
Glyoxylate metabolism and glycine degradation 0.439975752998011 0.5215522176696694 0.6019821395569642 1.0 1.0 13 Q9NR77 1
Notch4 activation and transmission of signal to the nucleus 0.7588357588357753 0.5214397610967711 0.6020604590669736 1.0 1.0 2 Q92542 1
Rhoc gtpase cycle 0.3483035324630308 0.5185999762233425 0.6040397256645318 1.0 1.0 27 P49257,O75955,P42167,P42166,P27105,P41440,Q14254,Q14739 8
Signaling by erbb4 0.4566501230768666 0.5127314587726469 0.6081391807792405 1.0 1.0 6 P61201,Q92542,Q96J02,P16949 4
N glycan trimming in the er and calnexin calreticulin cycle 0.4287090182544633 0.5111037818087292 0.6092783879585206 1.0 1.0 15 P62191,Q9UKV5,Q9UBV2,Q9GZP9,Q9BUN8 5
Cdc42 gtpase cycle 0.3508407551297095 0.5076424287982176 0.6117041297077805 1.0 1.0 29 Q9UQB8,Q658P3,P42167,P27105,Q14739 5
Hedgehog ligand biogenesis 0.3729085805152051 0.500292936474874 0.6168688270083664 1.0 1.0 41 P60900,P28074,Q9UL46,P49721,P62191,O00231,Q92530,P28072,Q9UBV2,P61289,Q9GZP9 11
Translation of sars cov 1 structural proteins 0.4504199311232467 0.485263919485097 0.6274891457669451 1.0 1.0 6 Q10472 1
Ripk1 mediated regulated necrosis 0.4426752247085135 0.4829037766455775 0.6291640601110073 1.0 1.0 10 O75955,P41440,Q16543,Q14254 4
Depolymerisation of the nuclear lamina 0.4436993162390097 0.4761162356757192 0.6339915708865373 1.0 1.0 9 P02545,P42167,P20700,P42166,P06493,P50402 6
P75 ntr receptor mediated signalling 0.438233996635102 0.4754165634979042 0.6344900908850768 1.0 1.0 11 Q9NQC3,Q92542,O75962,P52565,P62258 5
Signaling by fgfr1 in disease 0.4410266602032962 0.4636306473989163 0.6429123929488054 1.0 1.0 9 P19174,P40763,O94905,Q9UBW7,O95684 5
Organelle biogenesis and maintenance 0.4462043726774241 0.461391335094661 0.6445178670230067 1.0 1.0 85 P06576,Q96CS2,P62258,Q10713,P07437,O75964,Q14203,Q9BUR5,P24539,P41208,O75935,A6NIH7,P56385,Q9BUF5,Q13561,P53350,O75947,Q68CZ6,Q6UXV4,Q96KP1,Q13885,Q16891,P00367,Q15691,P06493,P56134,Q9H6D7,P68371,O94927,Q9NX63,Q9BVA1,P04350,Q9Y512,Q9UPT5,O43805,O95684,Q9NVH1,O75431,P36542,Q13505,Q5XKP0 41
Transport to the golgi and subsequent modification 0.4283197529972275 0.4547540149325135 0.6492862163936477 1.0 1.0 75 P49257,O95249,Q15363,P62820,O75396,Q9Y6B6,Q96PC5,Q8N6T3,O75935,Q13561,P83436,Q9BVK6,Q9Y3B3,P24390,P49755,Q9Y296,P04066,Q14746,Q9HCU5,Q9H0U4,Q12907,P68371,Q9UJW0,Q9BVA1,O14579,Q16706,O60476,O15498,Q14789 29
G alpha q signalling events 0.4257480205557347 0.4476996980637744 0.6543699396076414 1.0 1.0 13 Q8N2K0,P51812 2
Abc transporters in lipid homeostasis 0.7290367290367259 0.4328416582900492 0.6651298068286648 1.0 1.0 2 P56589 1
Runx1 regulates estrogen receptor mediated transcription 0.7259182259182484 0.4239769725913245 0.6715826071050359 1.0 1.0 2 Q9HCL2 1
Runx2 regulates genes involved in cell migration 0.7259182259182226 0.4239769725912514 0.6715826071050892 1.0 1.0 2 P31751 1
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5197642163661583 0.4202025518755321 0.6743374907125348 1.0 1.0 4 Q15750,O15111,P05067 3
Aquaporin mediated transport 0.4342094343418897 0.4151876763604197 0.6780045196365914 1.0 1.0 6 P10644,Q99797,P63218,Q9UBI6 4
Er to golgi anterograde transport 0.4156106312852057 0.4115041364015383 0.6807029088155587 1.0 1.0 71 P49257,O95249,Q15363,P62820,O75396,Q9Y6B6,Q96PC5,Q8N6T3,O75935,Q13561,P83436,Q9BVK6,Q9Y3B3,P24390,P49755,Q9Y296,Q14746,Q9HCU5,Q9H0U4,Q12907,P68371,Q9UJW0,Q9BVA1,O14579,O15498,Q14789 26
Constitutive signaling by overexpressed erbb2 0.631195840554584 0.409511059168042 0.6821646525455425 1.0 1.0 3 Q16543,P62993 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.4098414893103647 0.4084031343717209 0.682977732657114 1.0 1.0 15 P51572,Q9NZ08,Q03518 3
Free fatty acids regulate insulin secretion 0.6291161178509522 0.4032527971959094 0.6867622627857437 1.0 1.0 3 O95573,P29992 2
Methylation 0.4301598960149857 0.4009946590465754 0.6884240561662445 1.0 1.0 7 P21964 1
Linoleic acid la metabolism 0.7141372141372104 0.3912390314665399 0.6956205600235643 1.0 1.0 2 P33121 1
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.5069054210270382 0.377154984728771 0.706058431202605 1.0 1.0 4 P53611 1
Cellular response to chemical stress 0.4124094112259127 0.3749483877615823 0.7076988515735196 1.0 1.0 72 P28074,Q9UL46,O43819,P49721,P62191,P13073,O00231,P00403,P09601,P20674,O14548,P28072,Q8TCT9,P61289,O75880,P30519,Q8TED1 17
Nrif signals cell death from the nucleus 0.7075537075537308 0.373479056159202 0.708791930284463 1.0 1.0 2 Q92542 1
Synthesis of substrates in n glycan biosythesis 0.3980038661850948 0.3697029706677801 0.7116038181145128 1.0 1.0 16 Q86YN1,P10619,P16278 3
Signaling by braf and raf1 fusions 0.3679275713224034 0.3662989006179488 0.7141420498584314 1.0 1.0 21 Q9NRY5,P51797 2
Signaling by retinoic acid 0.4141624062449032 0.3493929093986884 0.726794355804264 1.0 1.0 10 Q8NBN7,Q15120,Q9HBH5,P50416 4
Platelet homeostasis 0.4133586036338393 0.3457465916842226 0.7295331660454771 1.0 1.0 10 P20020,P16615 2
Ub specific processing proteases 0.3961818052873713 0.3451019855875269 0.7300177007653277 1.0 1.0 65 P60900,P28074,P14735,Q9UL46,P49721,P62191,O00231,P45880,Q15388,Q96K76,P28072,P61289,P21796,Q9Y277 14
Translation of replicase and assembly of the replication transcription complex 0.4145231593362662 0.3332944963148601 0.738911993432029 1.0 1.0 6 Q9UQN3 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.4920249653259365 0.3292841913874976 0.7419408919144908 1.0 1.0 4 Q9BXS5,Q10567,P04439 3
Role of second messengers in netrin 1 signaling 0.6895356895356852 0.3269384065003728 0.7437144717022197 1.0 1.0 2 Q00169 1
Aflatoxin activation and detoxification 0.6010164935681259 0.3225289343464447 0.7470520214642873 1.0 1.0 3 Q99735 1
Presynaptic function of kainate receptors 0.6860706860706818 0.3183480751775024 0.7502209208934614 1.0 1.0 2 Q9UBI6 1
Prostacyclin signalling through prostacyclin receptor 0.6860706860706818 0.3183480751775024 0.7502209208934614 1.0 1.0 2 Q9UBI6 1
Glucagon type ligand receptors 0.6860706860706818 0.3183480751775024 0.7502209208934614 1.0 1.0 2 Q9UBI6 1
Potassium channels 0.6860706860706818 0.3183480751775024 0.7502209208934614 1.0 1.0 2 Q9UBI6 1
Inwardly rectifying k channels 0.6860706860706818 0.3183480751775024 0.7502209208934614 1.0 1.0 2 Q9UBI6 1
Signaling by mapk mutants 0.6850311850311805 0.3157942290927212 0.7521586986623936 1.0 1.0 2 Q99956 1
Degradation of axin 0.3411571313803037 0.3131326775259722 0.7541798635013506 1.0 1.0 37 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Cross presentation of soluble exogenous antigens endosomes 0.3411571313803037 0.3131326775259722 0.7541798635013506 1.0 1.0 37 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Rnd1 gtpase cycle 0.4040477369514368 0.3128203507082928 0.7544171531702897 1.0 1.0 11 Q9BXS4,P51648 2
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4838834132088676 0.3040520693947167 0.761088222154878 1.0 1.0 4 O14734,P51659 2
Death receptor signalling 0.3855523214091623 0.3029703623283294 0.7619124481541779 1.0 1.0 16 Q9NQC3,Q92542,O75962,Q15750,P52565,Q13501,P62258 7
Prevention of phagosomal lysosomal fusion 0.4830097087378642 0.3013867505541773 0.7631195964330706 1.0 1.0 4 Q9H267,P20339,P51149 3
Regulation of lipid metabolism by pparalpha 0.3693796857978966 0.297390114638235 0.7661686898647693 1.0 1.0 19 P23786,P04035,Q9NPJ6 3
Maturation of sars cov 2 spike protein 0.3993707909402008 0.291583134990844 0.7706053716865353 1.0 1.0 11 P46977,P04843,Q9H0U3,Q16706 4
Ecm proteoglycans 0.6715176715176667 0.2835902067656262 0.776724442993787 1.0 1.0 2 P05067 1
Cargo trafficking to the periciliary membrane 0.3770436775880527 0.2818895877317472 0.7780281737072421 1.0 1.0 17 A6NIH7 1
Synthesis of pips at the plasma membrane 0.4008164086979108 0.278600676145597 0.7805512937558623 1.0 1.0 7 P61106,Q9BTU6 2
Signaling by cytosolic fgfr1 fusion mutants 0.3997583988702603 0.2743756991107627 0.7837959159838963 1.0 1.0 7 O95684 1
Muscle contraction 0.3150722748977231 0.2728515166158788 0.7849673569101898 1.0 1.0 26 P05023,P08670,P16615,P20020 4
Signaling by fgfr in disease 0.3797716374698536 0.272710520881619 0.7850757466616638 1.0 1.0 16 O95684,O94905,P35269 3
Suppression of phagosomal maturation 0.3991669559180938 0.27202018929796 0.7856064956655799 1.0 1.0 7 P20339,Q9H267,Q9UI12,P52294,O14964,P51149 6
Activation of nmda receptors and postsynaptic events 0.3642689684860983 0.2678825827374232 0.788789700840387 1.0 1.0 19 P10644,Q9BUF5,Q9BVA1,P07196,P04350,P28482,P52292,Q13885,P68371,P51812,O14936 11
Rho gtpases activate nadph oxidases 0.4715672676837726 0.2672720104936523 0.7892597355066859 1.0 1.0 4 Q99570,Q16539,P28482 3
Interleukin 15 signaling 0.6607761607761675 0.2593448717123636 0.7953691607717106 1.0 1.0 2 P40763 1
Signal attenuation 0.6607761607761558 0.2593448717123371 0.795369160771731 1.0 1.0 2 P28482 1
Dap12 signaling 0.6607761607761558 0.2593448717123371 0.795369160771731 1.0 1.0 2 P19174 1
Signaling by ntrk3 trkc 0.6607761607761558 0.2593448717123371 0.795369160771731 1.0 1.0 2 P19174 1
Signaling by fgfr4 in disease 0.6607761607761558 0.2593448717123371 0.795369160771731 1.0 1.0 2 P19174 1
E3 ubiquitin ligases ubiquitinate target proteins 0.3804230611137611 0.2560481034453228 0.7979136938333244 1.0 1.0 15 Q14527,Q5VTR2,O75381,Q9BUN8,O75150 5
Signaling by kit in disease 0.5736568457538941 0.2514815439035698 0.8014418296261305 1.0 1.0 3 P62993,P40763 2
Interleukin 2 family signaling 0.5736568457538941 0.2514815439035698 0.8014418296261305 1.0 1.0 3 P62993,P40763 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5736568457538941 0.2514815439035698 0.8014418296261305 1.0 1.0 3 P62993,P40763 2
Methionine salvage pathway 0.5710050624137984 0.24502559475839 0.8064366135575982 1.0 1.0 3 Q13126 1
Regulation of runx3 expression and activity 0.3321250840450673 0.2320475808233301 0.8165010580635632 1.0 1.0 38 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Camk iv mediated phosphorylation of creb 0.646569646569663 0.2291788096436659 0.818729941764196 1.0 1.0 2 P52292 1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.646569646569663 0.2291788096436659 0.818729941764196 1.0 1.0 2 P52292 1
Lysosome vesicle biogenesis 0.3758853962855409 0.218159881764886 0.8273045419262806 1.0 1.0 14 Q9BXS5,O43633,P20645,P50570,P51809,P15586 6
Downstream signaling events of b cell receptor bcr 0.3355701643686443 0.2168985330061238 0.8282874208840778 1.0 1.0 41 P60900,P28074,Q9UL46,P62942,P49721,P62191,O00231,Q92530,P28072,P61289 10
Calnexin calreticulin cycle 0.3836355637027687 0.2131127220556595 0.8312390418090434 1.0 1.0 9 Q9UBV2,Q9GZP9,Q9UKV5 3
Cell death signalling via nrage nrif and nade 0.3811928706388885 0.2027310504733436 0.8393452523297982 1.0 1.0 7 Q92542,O75962,P62258 3
Tp53 regulates transcription of death receptors and ligands 0.6295911295911236 0.1960405507483769 0.8445784268475529 1.0 1.0 2 P49327 1
Association of tric cct with target proteins during biosynthesis 0.3604828437648746 0.1948598616859338 0.8455026575312692 1.0 1.0 17 Q99832,Q9Y2T2,O95302,P04062,P61962 5
Cdt1 association with the cdc6 orc origin complex 0.3284804830053158 0.1922428115093397 0.8475520125311002 1.0 1.0 39 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Endosomal sorting complex required for transport escrt 0.3745595140020258 0.1840979490870764 0.8539366153738737 1.0 1.0 11 Q9NZZ3,Q9UQN3 2
Budding and maturation of hiv virion 0.3747841920799519 0.1806459961252965 0.8566454500834069 1.0 1.0 10 Q9NZZ3,Q9UQN3 2
Diseases associated with glycosylation precursor biosynthesis 0.3750994425183144 0.1790829076024602 0.8578726028040089 1.0 1.0 8 P10619 1
Regulation of ras by gaps 0.3244772810411663 0.1767427041765147 0.8597104957968544 1.0 1.0 38 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Degradation of dvl 0.3244772810411663 0.1767427041765147 0.8597104957968544 1.0 1.0 38 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Activation of bad and translocation to mitochondria 0.3742150732468493 0.1757819035175515 0.8604652871569551 1.0 1.0 8 P31751,Q04917,P63104,P62258 4
G1 s dna damage checkpoints 0.3254096034851984 0.1703115018915622 0.8647651662064753 1.0 1.0 39 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Stabilization of p53 0.3254096034851984 0.1703115018915622 0.8647651662064753 1.0 1.0 39 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Scf skp2 mediated degradation of p27 p21 0.3272189297660088 0.1701554729819854 0.8648878684006667 1.0 1.0 40 P11802,P60900,P28074,Q9UL46,P49721,P62191,O00231,Q92530,P28072,P61289 10
Assembly of the hiv virion 0.6077616077616026 0.1581855309258434 0.8743106048525839 1.0 1.0 2 Q9H9H4 1
Regulation of pten stability and activity 0.3281014981046181 0.1506768129536809 0.8802306649623397 1.0 1.0 42 P60900,P28074,Q9UL46,P49721,P62191,O00231,Q92530,P28070,P28072,P61289 10
Signaling by notch4 0.3298199278688549 0.1499936052977176 0.88076966041769 1.0 1.0 43 P28074,Q92542,Q9UL46,P49721,P62191,O00231,P28072,P61289 8
Disorders of transmembrane transporters 0.3837328485682212 0.147021046964892 0.8831154077616279 1.0 1.0 74 P62191,Q92621,Q9NUN5,P61289,Q8N1F7,P08195,Q9BTX1,P28074,Q9UL46,P35613,O00231,P53985,Q9BUN8,O94905,O75477,P28072,P60900,P49721,Q92530,Q9UBV2,Q9GZP9 21
Late endosomal microautophagy 0.3641291897121821 0.1418898729307795 0.8871669936133637 1.0 1.0 11 P08670,Q9UQN3 2
Effects of pip2 hydrolysis 0.5184091633910727 0.1340365960909867 0.893373636029497 1.0 1.0 3 Q8N2K0 1
Arachidonate production from dag 0.5184091633910727 0.1340365960909867 0.893373636029497 1.0 1.0 3 Q8N2K0 1
Platelet activation signaling and aggregation 0.3414936349083278 0.1312913500529528 0.8955448342191057 1.0 1.0 51 P07602,Q8NCG7,O94919,Q8N2K0,Q92520,Q8NBX0,Q9NZJ7,Q9NUQ9,P13473 9
Antigen processing cross presentation 0.3385264948083011 0.1231867024445903 0.901959255277062 1.0 1.0 50 P28074,Q9UIQ6,Q9UL46,P49721,P62191,O00231,Q03518,P10321,P28072,P61289 10
Fceri mediated nf kb activation 0.3213751559211202 0.1166394322884129 0.9071457885324756 1.0 1.0 41 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5046793760831865 0.1106222488915389 0.9119159037051552 1.0 1.0 3 P35270,P07900 2
Ra biosynthesis pathway 0.4066706613092664 0.105396533475889 0.9160611666310364 1.0 1.0 4 Q8NBN7,Q9HBH5 2
Degradation of the extracellular matrix 0.3806712934960514 0.1052492416467531 0.9161780384818304 1.0 1.0 5 P35613 1
Translation of sars cov 2 structural proteins 0.3442511865032143 0.0994873084455389 0.9207513642995168 1.0 1.0 16 P04843,Q9H0U3,Q16706,Q10472,P46977 5
Negative regulation of notch4 signaling 0.3170215406513548 0.0993048991551829 0.9208961886835176 1.0 1.0 40 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Inositol phosphate metabolism 0.496707105719231 0.0980975338321666 0.9218548457995528 1.0 1.0 3 P19174,Q9BW91 2
Asymmetric localization of pcp proteins 0.3131921063727318 0.098014826280182 0.921920520387113 1.0 1.0 38 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Signaling by the b cell receptor bcr 0.3221654471353117 0.0973518637295149 0.9224469702580768 1.0 1.0 43 P60900,P28074,Q9UL46,P62942,P49721,P62191,O00231,Q92530,P28072,P61289 10
Deadenylation of mrna 0.3461153611249912 0.0957656397768384 0.9237067073808088 1.0 1.0 15 O95628,Q9H074,Q14240 3
Tnf signaling 0.4015256588072124 0.0950951872424505 0.924239220777692 1.0 1.0 4 Q15750,O15111,Q6GQQ9 3
Tnfr1 induced nfkappab signaling pathway 0.4015256588072124 0.0950951872424505 0.924239220777692 1.0 1.0 4 Q15750,O15111,Q6GQQ9 3
Activation of the ap 1 family of transcription factors 0.5606375606375529 0.0945460946267664 0.9246753681883696 1.0 1.0 2 P28482 1
Ovarian tumor domain proteases 0.3459403192227537 0.0873667179687879 0.9303800234062596 1.0 1.0 6 Q96FW1,Q6GQQ9,P04637,P06493,P55072 5
Syndecan interactions 0.3965311465426131 0.0854702905024907 0.9318875137664242 1.0 1.0 4 Q9Y296,O14936 2
Non integrin membrane ecm interactions 0.3965311465426131 0.0854702905024907 0.9318875137664242 1.0 1.0 4 Q9Y296,O14936 2
Ca dependent events 0.3444492420970261 0.0828787061497862 0.9339479858107582 1.0 1.0 6 P10644,P52292,P13861,P28482 4
Hyaluronan uptake and degradation 0.3680194242108906 0.07405258634916 0.9409685422309506 1.0 1.0 5 P06865,O75330,Q9UHD1,P08236 4
Hyaluronan metabolism 0.3680194242108906 0.07405258634916 0.9409685422309506 1.0 1.0 5 P06865,O75330,Q9UHD1,P08236 4
Irf3 mediated activation of type 1 ifn 0.5381150381150297 0.0723744296783134 0.9423039335784112 1.0 1.0 2 Q9UHD2 1
Cyclin a cdk2 associated events at s phase entry 0.3164793668487503 0.0713261795804659 0.9431381599948578 1.0 1.0 42 P11802,P60900,P28074,Q9UL46,P49721,P62191,O00231,Q92530,P28070,P28072,P61289 11
Circadian clock 0.3453604284676493 0.0711346504687218 0.943290590925014 1.0 1.0 11 P43490 1
Rhoj gtpase cycle 0.3268427202538032 0.0673925832444268 0.9462691734806196 1.0 1.0 19 O75962,Q9Y6M7,Q658P3,P42167,P42166,Q15758,P27105,P02786 8
Binding and uptake of ligands by scavenger receptors 0.3401410364096299 0.0640888553622877 0.9488994757360292 1.0 1.0 7 Q8WTV0 1
Degradation of gli1 by the proteasome 0.3132566573591097 0.0619338637130962 0.9506154999083004 1.0 1.0 41 P60900,P28074,Q9UL46,P49721,P62191,O00231,Q92530,P28070,P28072,P61289 10
Diseases of immune system 0.5194040194040128 0.0575947178313999 0.954071457250375 1.0 1.0 2 O15111 1
Protein folding 0.3034287159454771 0.0569419294622075 0.9545914535970376 1.0 1.0 36 Q9BUF5,Q9BVA1,P40763,Q99471,Q9UBI6,O15212,P61962,P63218,P04350,Q99832,Q9Y2T2,O95302,Q9UHV9,Q13885,P04062,P68371,P29992,O75347 18
Orc1 removal from chromatin 0.3247602843539814 0.0550569059695398 0.9560931280930488 1.0 1.0 48 P28074,Q9UL46,P49721,P62191,O00231,P33991,P28072,P61289 8
Bile acid and bile salt metabolism 0.3339118361680036 0.0457999413058851 0.9634697055943262 1.0 1.0 7 O14975,O14734,P51659,Q96SU4,Q9BZF3,P22307 6
Synthesis of bile acids and bile salts 0.3339118361680036 0.0457999413058851 0.9634697055943262 1.0 1.0 7 O14975,O14734,P51659,Q96SU4,Q9BZF3,P22307 6
Vasopressin regulates renal water homeostasis via aquaporins 0.3551764916596023 0.0451951843134952 0.9639517326911308 1.0 1.0 5 P10644,P63218,Q9UBI6 3
Glucagon signaling in metabolic regulation 0.3551764916596023 0.0451951843134952 0.9639517326911308 1.0 1.0 5 P10644,P63218,Q9UBI6 3
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4889119889119821 0.0396852968840223 0.9683440238297572 1.0 1.0 2 P49916 1
Phenylalanine metabolism 0.4688149688149593 0.0314041435253359 0.9749472367272278 1.0 1.0 2 P61457 1
Pre notch expression and processing 0.3337133039748798 0.0309348059622263 0.975321532054314 1.0 1.0 11 Q15363 1
Negative feedback regulation of mapk pathway 0.4674289674289633 0.0309211338673538 0.9753324355916482 1.0 1.0 2 P28482 1
Folding of actin by cct tric 0.3302083333333354 0.0294694661411329 0.9764901708497684 1.0 1.0 8 P50990,Q99832,P78371,P49368,P17987,P48643,P50991 7
Activation of smo 0.4414414414414334 0.0236457871315943 0.9811351494988004 1.0 1.0 2 P48729 1
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3307826086956534 0.022576198915252 0.9819883295025532 1.0 1.0 13 P67870,P50990,P19784,Q9UBI6,P63218,Q99832,P17987,P78371,P29992,P49368,P48643,P50991 12
Formation of tubulin folding intermediates by cct tric 0.3307826086956474 0.0225761989152308 0.98198832950257 1.0 1.0 13 P50990,Q9BVA1,Q9BUF5,P04350,Q99832,P17987,Q13885,P68371,P78371,P49368,P48643,P50991 12
Other interleukin signaling 0.4144144144144027 0.0189667120153911 0.9848676605941212 1.0 1.0 2 Q15833 1
Josephin domain dubs 0.3939708939708843 0.0168091098358781 0.9865889023264752 1.0 1.0 2 P54727 1
Cs ds degradation 0.367636867636859 0.015190352380183 0.9878803184607888 1.0 1.0 2 P06865 1
Traf6 mediated irf7 activation 0.345460845460837 0.014473899320756 0.9884519024078288 1.0 1.0 2 Q9UHD2 1
Traf3 dependent irf activation pathway 0.345460845460837 0.014473899320756 0.9884519024078288 1.0 1.0 2 Q9UHD2 1
Vegfr2 mediated cell proliferation 0.3447678447678355 0.0144580433925535 0.9884645522844852 1.0 1.0 2 P19174 1
Transcriptional regulation of pluripotent stem cells 0.3139293139293075 0.0140111240177805 0.9888211062256622 1.0 1.0 2 P40763 1
Dcc mediated attractive signaling 0.27720027720027 0.0138449761779298 0.988953660164006 1.0 1.0 2 O75962 1
Ca2 pathway 0.3462191902848853 0.0090256468064154 0.992798673534804 1.0 1.0 4 Q9HCE1,Q9UBI6 2
Traf6 mediated nf kb activation 0.3457004160887657 0.0084262305792208 0.9932769202731382 1.0 1.0 4 O15111,P09429,P05067 3
Tnfr2 non canonical nf kb pathway 0.3067375861880768 0.0082334179724531 0.9934307571378151 1.0 1.0 42 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Dectin 1 mediated noncanonical nf kb signaling 0.3067375861880769 0.0082334179724531 0.9934307571378151 1.0 1.0 42 P28074,Q9UL46,P49721,P62191,O00231,P28072,P61289 7
Regulation of tnfr1 signaling 0.401386481802422 0.0042655110446268 0.9965966249140604 1.0 1.0 3 O15111,Q6GQQ9 2
Formyl peptide receptors bind formyl peptides and many other ligands 0.3949216120968479 0.0010637895872045 0.9991512188725136 1.0 1.0 3 Q9NRV9 1