diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c449dabb529e19d7c1e039b4abd75b60cdd40aa5 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f0126654f04cd62b324396105c83a11d9993c3c004194f7852af02ef1182cec +size 80469 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..392388d40cf2a11f57a34340d92b29fb7272efb9 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cysteine peptidase, cysteine active site [IPR000169] 0 5 2.1061814587326144 0.0351885930936524 1.9927184466019416 4.106796116504855 -0.4055096631049736 0.4078826502023353 1.2157723137108922 1.0442874781746152 1.1544656254210668 0.3023405414752508 0.0860283086388496 1.0 0.1027954944442906 0.2382253475836706 0.4230365159515766 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d75d4d068a690338f7a10dd4aecdafb9a3637e30 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 2.6545454545454548 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d32afb7ae777d10c589848fe23629739a355aecb --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..58779ed21c5b2e8ca9ae951541e22fe64014912c --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9800891530460624 1.72900761142083 0.0838077328375528 0.9918854543837996 0.2880890816290878 3 P10619,Q9HB40 2 +Tyrosine-protein kinase, active site [IPR008266] 0.7231029322270788 1.5558235138671173 0.1197500651032714 0.9991018888478596 0.3136311228895205 6 Q15375,P29317 2 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.6593320848730937 1.2985430881894997 0.1941007800136935 0.9999929944788508 0.4448142875313811 6 P49459,P61088 2 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7410720886932611 0.8785885045193506 0.3796244309299585 0.9999999999960554 0.5643547403710597 3 Q8TBC4 1 +L-lactate dehydrogenase, active site [IPR018177] 0.608734402852059 0.4508866029133952 0.6520712796609458 1.0 0.7496539290657324 2 P00338 1 +Protein-tyrosine phosphatase, active site [IPR016130] 0.4294852348841915 0.4478749762312777 0.654243429002821 1.0 0.7496539290657324 7 P10586,P51452,Q8NCE2 3 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c1b02160848d0de021e2322608dfb3b4cb7c2e3e --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP8", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK1", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["CTSA", "DUSP3", "EPHA2", "EPHA7", "LDHA", "MTMR14", "PTPRF", "SCPEP1", "UBA3", "UBE2A", "UBE2N"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..905eee735d1673e575052abfc753d2c9348ec546 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:01504de1ac08b9971761c8253c84028ace27fd82fb7c73b7bb89fde564dbd192 +size 139335 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8eed49ec903a47620d479ebe0355d8125de5879e --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b75bfdf5cf38d4ebb2b70b5341cd8b16a8c46540fa35049493d645ff80331234 +size 75726 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9c9290d4d42f9a47a20b3c5d7766121079dcd7b6 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 30, + "title": "Average number of proteins per term", + "value": 4.8 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8223eb7dff2b2094aeafb82d43debd708b66f9c8 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3f6c2e3347f3485c23a54325e7433b3c66891a12 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin, autoregulation binding site [IPR013838] 0.7906926789702013 1.7089005107054034 0.0874693799111903 0.935816501549314 0.3748687710479584 5 P04350,Q9BUF5,P07437 3 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.8698752228164003 1.3868269031568878 0.1654945514415304 0.995605845759745 0.4783563609734939 2 Q9H0C8 1 +Peptidase M16, zinc-binding site [IPR001431] 0.6114381891437337 1.0044669753537057 0.3151535815734738 0.9999883105072596 0.4962932890339371 5 Q10713 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.4174683694184192 0.9396340538569772 0.347405302323756 0.9999972501675992 0.4962932890339371 39 P80303,O43852,O95302,Q14257,Q7L5N7,P41208,Q02818,P42566,Q9H223,Q9H4M9 10 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..02c8ef1752d8a55085ebb2bdd657d596a4e23b31 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CETN2", "CIB1", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK3", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "CETN2", "EHD1", "EHD4", "EPS15", "FKBP9", "ILKAP", "LPCAT2", "NUCB1", "NUCB2", "PMPCA", "RCN2", "TUBB", "TUBB4A", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..978cd334474c7348df2b7586abef108e392311a4 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Cadherin conserved site [IPR020894]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5ddd9f39d53d4e62f3e1a6b08ad32fcc4e8a8801 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb84a6695eff8097a1fa921d817001cfe44af18c092ec53cc8d21661a1dadc4c +size 186375 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d570cdcf18088a178ca6e00c52b65f98b599a1ea --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cadherin conserved site [IPR020894]", "1": "Chaperonin TCP-1, conserved site [IPR002194]", "2": "Mini-chromosome maintenance, conserved site [IPR018525]", "3": "Ubiquitin specific protease, conserved site [IPR018200]", "4": "Cullin, conserved site [IPR016157]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d498b2a6e45e1b348cb5079130ffbbd0ac41f1ea --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:705b3488f8e6d777efe74d657d80e872e54891b8dcf1a80987c1ecb897a246b7 +size 138250 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e72b17219b840e47816f3abe700784a3c9dbe550 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21b242a1bac6a7ed2bcef8ab21ecf5ce5d7bcaaa475b09180592b788dc088289 +size 141792 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e145c23d94abc9403bda54ac21920f695fe08d2f --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3274686fa1b067390f19fe20bb889b6266f9cd44f5694439a6571fe03a8a8fd +size 144963 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5c2ee8039cfd82673a109750222a58287c6a5c7a --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc8e3578880bf259f19f5e78deece18cc72d9defd308f8b03bce40677d73deea +size 153402 diff --git a/interpro_conserved_site/basic/plot_4.png b/interpro_conserved_site/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bd2c0d4ac333504305daf1749a22b6d5daea49c8 --- /dev/null +++ b/interpro_conserved_site/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:179d9c5a51f7738c183b46544b72f2ded2e518e689209a08a333e8a2285d8a43 +size 141351 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ef388b15d20e738da2b21c6cbb7f53bf8731c057 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb00d8c7360037237f91dd8c53f9a9a397c4e79f5563062ba7ee1226161dc359 +size 101003 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e0cd59509d3bf44e938f417ef8db16352c8d7a01 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-like calcium-binding, conserved site [IPR018097] 4 6 2.459003237015357 0.0139323361585412 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 1.1245333568397323e-05 0.0007667347448651 2.788863476938184e-05 0.0019200914773881 0.0083426651664859 +Cadherin conserved site [IPR020894] 5 6 2.408979089445935 0.0159972145155091 1.555825242718447 3.0558252427184467 -0.2693089236279177 0.4378099575304214 1.0377767725547085 1.0517161419538543 1.2797396443463749 0.3315735399503712 0.0003886260619154 0.0034296220851759 0.0006712136127385 2.898375171077518e-06 0.0001461959825676 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1f22c9cd22dc48c67362071143d25b27abcff2ce --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 286, + "title": "Average number of proteins per term", + "value": 2.800699300699301 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..135b8ea4163ea3f72d10e73139817489aafac557 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..032adb31330695c538066981b5a22ca7b7e8f45e --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,51 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-like calcium-binding, conserved site [IPR018097] 0.9573548133831954 2.459003237015357 0.0139323361585412 0.9819148915053209 0.1106846705928557 6 P01130,P48960,Q07954,Q14517 4 +Cadherin conserved site [IPR020894] 0.9437834622248692 2.408979089445935 0.0159972145155091 0.9900699883815752 0.1173129064470672 6 Q14126,Q02487,O60245,Q14517,Q14574 5 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9943553178847296 1.879963867978085 0.0601130024193001 0.9999999800642078 0.2387822040544423 2 Q06481 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9943553178847296 1.879963867978085 0.0601130024193001 0.9999999800642078 0.2387822040544423 2 Q06481 1 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9943553178847296 1.879963867978085 0.0601130024193001 0.9999999800642078 0.2387822040544423 2 Q06481 1 +C-type lectin, conserved site [IPR018378] 0.9919786096256684 1.870600988739804 0.0614004074662644 0.9999999865295116 0.2405550210322139 2 Q5KU26 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9896019013666072 1.861234252074333 0.0627111033394731 0.9999999909673938 0.2423699399336395 2 Q9BTY2 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9789067142008324 1.819038463872372 0.0689055620861074 0.9999999986441632 0.246337384457834 2 P13473 1 +Glycoside hydrolase, family 35, conserved site [IPR019801] 0.977421271538919 1.81317233862047 0.0698052447719372 0.9999999989716724 0.2464728395651118 2 P16278 1 +Tetraspanin, conserved site [IPR018503] 0.968805704099822 1.779123945205994 0.0752194437526205 0.9999999998063288 0.2539790244182682 2 O60637 1 +Tyrosine-protein kinase, receptor class V, conserved site [IPR001426] 0.9649435531788472 1.7638479097838546 0.0777575888288795 0.9999999999117538 0.2539790244182682 2 Q15375 1 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.9893016344725112 1.7620069917324217 0.0780681161890117 0.9999999999198568 0.2539790244182682 3 P01130,Q9NPF0 2 +Sterol reductase, conserved site [IPR018083] 0.9489007724301846 1.7003193512248311 0.0890708724447917 0.9999999999974142 0.2687164902299718 2 Q9UBM7 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.9717682020802376 1.6991624711612954 0.0892885753319694 0.999999999997585 0.2687164902299718 3 P55899,P04439 2 +Proteasome beta-type subunit, conserved site [IPR016050] 0.7197531120729921 1.6870023905956415 0.0916028922826137 0.9999999999988336 0.2687164902299718 8 P49721,P28070,P28074,P28072 4 +Tubulin, conserved site [IPR017975] 0.7515106313608246 1.6693925653123427 0.0950396061009781 0.9999999999996056 0.2687164902299718 6 P04350,Q9BUF5,Q13885,P07437 4 +Sugar transporter, conserved site [IPR005829] 0.9340463458110532 1.64141217368709 0.1007118845460905 0.9999999999999348 0.2769576825017491 2 Q7L0J3 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.920653789004458 1.5152339310474894 0.129713173099158 1.0 0.3392342686937837 3 O15347,P09429 2 +EGF-like, conserved site [IPR013032] 0.8704693998811688 1.38917885700389 0.1647783692805997 1.0 0.3920601264567657 2 O94813 1 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.8149138443256119 1.1706689908640917 0.2417318541528428 1.0 0.5083478697625959 2 P24534 1 +Ubiquitin interacting motif [IPR003903] 0.6988703923900054 1.159218479157039 0.2463671409099126 1.0 0.5143138854031752 4 P42566,O14964,P55036 3 +Profilin conserved site [IPR027310] 0.781639928698755 1.0420612261717273 0.2973832937017713 1.0 0.5632557748258714 2 P07737 1 +Purine phosphorylase, family 2, conserved site [IPR018099] 0.7254901960784361 0.8321341851742442 0.4053332079046619 1.0 0.6700884246285161 2 P00491 1 +ABC transporter-like, conserved site [IPR017871] 0.4582371195532446 0.7909813057477627 0.4289549005260773 1.0 0.6892196716317871 13 P08183,Q9NUQ8,P33527 3 +Histidine triad, conserved site [IPR019808] 0.7043969102792688 0.7566058829622321 0.4492860157674561 1.0 0.6970502186210047 2 Q96C86 1 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.6975890634199353 2 P28482 1 +GTP1/OBG, conserved site [IPR006074] 0.6868686868686931 0.6956596044560157 0.4866420290449387 1.0 0.705708968828734 2 P55039 1 +Chaperonin TCP-1, conserved site [IPR002194] 0.4776785714285732 0.6666728900959488 0.5049810989779508 1.0 0.7185303199387758 8 P40227,P49368,P50991,P50990,P48643,P17987,Q99832 7 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.6681521093285869 0.6326958953936118 0.5269322508049219 1.0 0.7245404232667391 2 P06737 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.6637524546258105 0.628051183159669 0.5299704109741226 1.0 0.7245404232667391 3 P08238 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.6660724896019086 0.6258478593756066 0.531414736869972 1.0 0.7245404232667391 2 O00429 1 +Phosphofructokinase, conserved site [IPR015912] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.7245404232667391 3 Q01813,P08237 2 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.6476530005941847 0.5666064421186956 0.57098159717426 1.0 0.7389173610490424 2 Q96FJ2 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.6307189542483743 0.5145688336012798 0.606854348565603 1.0 0.7729281507175766 2 P09884 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.4428627832330521 0.467736084697735 0.6399733327668782 1.0 0.8063100139706042 6 Q86Y82,O15400,P56962 3 +14-3-3 protein, conserved site [IPR023409] 0.4191461236081376 0.3924702498270574 0.6947107888963626 1.0 0.8383429773179735 6 P27348,P62258,P63104 3 +Mini-chromosome maintenance, conserved site [IPR018525] 0.4048185603807373 0.3499470661054144 0.7263784238826794 1.0 0.8444887367091314 6 P49736,P33991,P33992,P25205,P33993 5 +Ubiquitin specific protease, conserved site [IPR018200] 0.3488341133706288 0.3080040184010574 0.7580792746475429 1.0 0.8777760022234707 14 Q8TEY7,P54578,Q96K76,P45974,P51784 5 +Enolase, conserved site [IPR020809] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.8840559107494798 2 P09104 1 +Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.5069836552748901 0.2455889938735746 0.8060004099668792 1.0 0.9111308982234286 3 P36871,O95394 2 +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.9216723731910844 2 P30046 1 +Vinculin, conserved site [IPR000633] 0.4569221628045304 0.161062463523277 0.8720442039738532 1.0 0.942438991235151 2 P18206 1 +Cullin, conserved site [IPR016157] 0.3233194527067131 0.1602680803612778 0.8726699020032556 1.0 0.942438991235151 6 Q13619,Q93034,Q13620,Q13617,Q13618 5 +Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.4385026737968021 0.1444866494592041 0.885116198020053 1.0 0.9481019948829033 2 P04075 1 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.400475341651823 0.1205053647086975 0.9040828301926752 1.0 0.9542889283750752 2 O15160 1 +Serpin, conserved site [IPR023795] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.9542889283750752 2 P35237 1 +Ribosomal protein S2, conserved site [IPR018130] 0.3903743315508098 0.1160972297239747 0.9075754843287428 1.0 0.9542889283750752 2 P08865 1 +Clathrin adaptor complex, small chain [IPR000804] 0.357991681521101 0.1062172736645141 0.9154099660731893 1.0 0.9549357748128072 2 P53680 1 +DNA ligase, ATP-dependent, conserved site [IPR016059] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9549357748128072 2 P18858 1 +Guanylate kinase, conserved site [IPR020590] 0.2886475922555089 0.1026919336892036 0.9182074757815456 1.0 0.9549357748128072 7 Q14168,Q12959 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..989fe81150d11b89068d71b3f4cc7947beaf71de --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, NFYB/HAP3, conserved site [IPR003956]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC40", "CDH2", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPA1", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA6", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAGI3", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF2", "NFYB", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RING1", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SHPRH", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM2", "STMN1", "STOM", "STRN", "STRN4", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TATDN1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCC1", "ABCF3", "ADGRE5", "ALDOA", "AP2S1", "APLP2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "COLEC12", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "DCPS", "DDT", "DHCR7", "DLG1", "DNM1L", "DRG2", "DSC2", "DSC3", "DSG2", "DYNLL2", "EEF1B2", "ENO2", "EPHA7", "EPS15", "FAT1", "FCGRT", "FUCA2", "GLB1", "HGS", "HLA-A", "HMGB1", "HMGB3", "HSP90AB1", "LAMP2", "LDLR", "LIG1", "LRP1", "MAPK1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM7", "MPP2", "PCDH7", "PFKM", "PFKP", "PFN1", "PGM1", "PGM3", "PNP", "POLA1", "POLR1C", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMD4", "PYGL", "RPSA", "SERPINB6", "SLIT2", "STX12", "STX17", "STX7", "SV2A", "TCP1", "TSPAN3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "USP11", "USP14", "USP33", "USP47", "USP5", "VCL", "YWHAE", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c8a00b455e15f719e64d48326d3d70ca5a745f91 --- /dev/null +++ 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pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Immunoglobulin-like domain [IPR007110] 16 20 3.2700118768847743 0.0010754296892216 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.2344878525078567 0.1058856107488554 0.0049970479011415 1.3261582698541364e-08 8.044098396899437e-06 +Immunoglobulin subtype [IPR003599] 12 15 2.947284674020073 0.0032057793066362 2.9684466019417477 8.483009708737864 0.1381371967634491 0.4928258967784709 2.271921156707309 2.9216637549507847 1.0756254869730633 0.312999744433737 0.5491527241932992 0.3806666514303258 0.2461545823107236 3.910587227514112e-06 0.000817736871328 +Immunoglobulin subtype 2 [IPR003598] 10 13 2.8049148027850306 0.0050329881165562 2.8106796116504853 8.04126213592233 0.1764352420775828 0.5005828106358552 2.0581551085254395 2.677802743524345 1.0491539805619012 0.3137632145774063 0.427451384124797 0.2849410889163232 0.1434310184114938 5.274129063048399e-06 0.0004056006267912 +EGF-like domain [IPR000742] 8 10 2.717122402022681 0.0065852248879885 1.812807881773399 3.940886699507389 -0.2515571357977262 0.397990648527913 1.5407225921455587 2.4527963737747185 1.3250723622342764 0.3076599741691995 3.363325698050656e-05 0.0060673937801388 9.611170637388942e-05 9.14386041821418e-05 0.0036518848204098 +EGF-like calcium-binding domain [IPR001881] 4 6 2.459003237015357 0.0139323361585412 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 2.12570833522401e-05 0.0011134897140002 5.2354492781690494e-05 0.0033942963153933 0.0153479918417224 +Cadherin-like [IPR002126] 5 6 2.408979089445935 0.0159972145155091 1.5898058252427183 3.1310679611650487 -0.2612861714701764 0.4372142450358497 1.076759324040342 1.1605597181786682 1.2840907797021492 0.3325457904266107 0.0006223592227998 0.0046633751497463 0.0010709052035729 7.965537894699164e-06 0.0003770934365041 +Immunoglobulin I-set [IPR013098] 6 9 2.40510085617444 0.0161680030110549 1.483009708737864 3.5436893203883497 -0.0396549694488073 0.564695829059301 1.2056512037685103 1.5596657535194778 0.9626777574921488 0.3192014691096427 0.3469532683251365 0.2260688267312995 0.4017902994798545 0.0015871230225135 0.012512209523234 +Fibronectin type III [IPR003961] 5 10 2.4024522894806672 0.0162855588023342 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.4414139941253555 0.295480255529908 0.5045129832066302 0.0076080813078773 0.131474990685951 +Immunoglobulin V-set domain [IPR013106] 5 6 2.359351400236784 0.0183069111964027 1.8814814814814815 3.639506172839506 -0.1240957684542258 0.411362008796823 1.3951513136318474 1.5958030613003984 1.3078070990153907 0.3212718057023477 1.0 1.0 0.2851312580635185 0.0001512549233666 0.0054583584483833 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 2 6 1.973040745678617 0.0484909202988617 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0633191306420368 0.0385773062479974 0.0758460972151271 0.0150927838189798 0.0053637976870067 +Aminopeptidase N-like , N-terminal domain [IPR045357] 2 6 1.973040745678617 0.0484909202988617 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0633191306420368 0.0385773062479974 0.0758460972151271 0.0150927838189798 0.0053637976870067 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1db8dc0ac36732d9d644e75b1ea412345b7a7a01 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 2755, + "title": "Average number of proteins per term", + "value": 2.2268602540834848 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8c4d44ce9fc9711a40ba967e28accef9de8287c7 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..282a138e9041a8237d79c847f79d989187138cd9 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,314 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Immunoglobulin-like domain [IPR007110] 0.9000161590835004 3.2700118768847743 0.0010754296892216 0.9484087442574782 0.0730609629689393 20 P55899,P04439,P01889,P13591,Q6PCB8,O94898,P10586,Q9Y624,Q92859,Q92692,P35613,Q9Y6N7,Q13740,P78310,P10321,P43121 16 +Immunoglobulin subtype [IPR003599] 0.8877034472274425 2.947284674020073 0.0032057793066362 0.9998560592662622 0.0730609629689393 15 P13591,Q6PCB8,O94898,P10586,Q9Y624,Q92859,Q92692,P35613,Q13740,Q9Y6N7,P78310,P43121 12 +Immunoglobulin subtype 2 [IPR003598] 0.8844639256602052 2.8049148027850306 0.0050329881165562 0.999999081839104 0.0730609629689393 13 P13591,O94898,P10586,Q9Y624,Q92859,P35613,Q13740,Q9Y6N7,P78310,P43121 10 +EGF-like domain [IPR000742] 0.924874239499936 2.717122402022681 0.0065852248879885 0.9999999875593146 0.0730609629689393 10 Q07954,P07942,Q08431,O94813,Q9P273,P01130,Q14517,P48960 8 +EGF-like calcium-binding domain [IPR001881] 0.9573548133831954 2.459003237015357 0.0139323361585412 1.0 0.0922165288201375 6 P01130,P48960,Q07954,Q14517 4 +Cadherin-like [IPR002126] 0.9437834622248692 2.408979089445935 0.0159972145155091 1.0 0.0951886090501679 6 Q14126,Q02487,O60245,Q14517,Q14574 5 +Immunoglobulin I-set [IPR013098] 0.8716770510057328 2.40510085617444 0.0161680030110549 1.0 0.0959975178781386 9 P13591,Q6PCB8,O94898,P10586,Q92859,Q9Y6N7 6 +Fibronectin type III [IPR003961] 0.8469650202433147 2.4024522894806672 0.0162855588023342 1.0 0.0962204177613077 10 P13591,Q92859,Q15375,P29317,Q9Y6N7 5 +Immunoglobulin V-set domain [IPR013106] 0.9303985722784084 2.359351400236784 0.0183069111964027 1.0 0.101424799748139 6 Q9Y624,Q9Y6N7,Q13740,P78310,P43121 5 +Immunoglobulin C1-set [IPR003597] 0.9640309155766932 2.15466065273199 0.0311883989851171 1.0 0.1344664150297304 4 P55899,P01889,P04439 3 +MHC class I-like antigen recognition-like [IPR011161] 0.9640309155766932 2.15466065273199 0.0311883989851171 1.0 0.1344664150297304 4 P55899,P01889,P04439 3 +MRH domain [IPR044865] 0.9455147657941844 2.0871268177158755 0.036876672485274 1.0 0.148191354812717 4 P20645,P11717 2 +Ricin B, lectin domain [IPR000772] 0.927523782480524 2.0211073119011296 0.0432686576074272 1.0 0.1630768789913039 4 Q9UBG0 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8287233876662697 1.973040745678617 0.0484909202988617 1.0 0.1721552647208299 6 P55786,Q9UIQ6 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8287233876662697 1.973040745678617 0.0484909202988617 1.0 0.1721552647208299 6 P55786,Q9UIQ6 2 +ERAP1-like C-terminal domain [IPR024571] 0.9132421652282796 1.9684274112865383 0.0490188805350446 1.0 0.173805683235583 4 Q9UIQ6 1 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1978629888472783 2 Q06481 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.9919786096256684 1.870600988739804 0.0614004074662644 1.0 0.1999504994912038 2 Q5KU26 1 +C-type lectin-like [IPR001304] 0.9919786096256684 1.870600988739804 0.0614004074662644 1.0 0.1999504994912038 2 Q5KU26 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9896019013666072 1.861234252074333 0.0627111033394731 1.0 0.2023057256443191 2 Q9BTY2 1 +MD-2-related lipid-recognition domain [IPR003172] 0.983363042186572 1.8366288284406111 0.0662647084995717 1.0 0.2090995847980626 2 P61916 1 +PA domain [IPR003137] 0.9824717765894242 1.833111734877538 0.0667859563385007 1.0 0.210040307891061 2 P02786 1 +Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147] 0.9821746880570412 1.831939260257983 0.0669604704813946 1.0 0.21034902642673 2 O00754 1 +Laminin G domain [IPR001791] 0.9783125371360668 1.8166921709677029 0.0692642611927776 1.0 0.2161076326003424 2 Q14517 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.9777183600713016 1.8143456682279615 0.0696245247990861 1.0 0.2167407523406578 2 O94813 1 +Glycoside hydrolase 35, catalytic domain [IPR031330] 0.977421271538919 1.81317233862047 0.0698052447719372 1.0 0.2169907749778553 2 P16278 1 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.9753416518122408 1.804957587878303 0.0710813190900347 1.0 0.2195392758890648 2 P06865 1 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.9753416518122408 1.804957587878303 0.0710813190900347 1.0 0.2195392758890648 2 P06865 1 +CBS domain [IPR000644] 0.7832593203890629 1.7952178675340515 0.0726189947949231 1.0 0.2220480917425231 6 P54619,P51790,Q8NE01,P51798 4 +CD80-like, immunoglobulin C2-set [IPR013162] 0.859858444850074 1.7695446644835475 0.0768030239896182 1.0 0.2307567688258979 4 P43121,Q13740 2 +Ephrin receptor ligand binding domain [IPR001090] 0.9649435531788472 1.7638479097838546 0.0777575888288795 1.0 0.2307567688258979 2 Q15375 1 +Ephrin receptor, transmembrane domain [IPR027936] 0.9649435531788472 1.7638479097838546 0.0777575888288795 1.0 0.2307567688258979 2 Q15375 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.964646464646465 1.7626725172782438 0.0779557385469007 1.0 0.2307567688258979 2 O43924 1 +CUB domain [IPR000859] 0.9625668449197876 1.7544435576127702 0.0793545332856455 1.0 0.232082525692097 2 Q6UXD5 1 +Coagulation factor 5/8 C-terminal domain [IPR000421] 0.9625668449197868 1.7544435576127662 0.0793545332856462 1.0 0.232082525692097 2 Q08431 1 +Fibronectin type II domain [IPR000562] 0.9754182757639832 1.7122587195952068 0.0868490004749091 1.0 0.2451526601520233 3 P11717 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6795906406404285 1.6839214024860718 0.0921968594905764 1.0 0.2563091300671423 10 O00170,O95302 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.963744427934621 1.67035123065311 0.0948498926681926 1.0 0.2590799305786122 3 P04439,P01889 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.963744427934621 1.67035123065311 0.0948498926681926 1.0 0.2590799305786122 3 P04439,P01889 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.2590799305786122 6 P04350,Q9BUF5,Q13885,P07437 4 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.2590799305786122 6 P04350,Q9BUF5,Q13885,P07437 4 +Laminin-type EGF domain [IPR002049] 0.9385026737967924 1.6590910321902188 0.0970974500768102 1.0 0.2620014446244978 2 P07942 1 +Laminin, N-terminal [IPR008211] 0.9385026737967924 1.6590910321902188 0.0970974500768102 1.0 0.2620014446244978 2 P07942 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.9604754829123328 1.6586050616803685 0.0971954011583342 1.0 0.2620091293456075 3 O94813,Q13641 2 +Immunoglobulin [IPR013151] 0.9545319465081724 1.6372371736887537 0.1015809225149215 1.0 0.266275396316469 3 Q6PCB8,P43121 2 +Cadherin prodomain [IPR014868] 0.9429420505200594 1.595533037844279 0.1105930881378893 1.0 0.2810021296120005 3 Q14574,Q02487 2 +Cadherin, cytoplasmic domain [IPR000233] 0.9429420505200594 1.595533037844279 0.1105930881378893 1.0 0.2810021296120005 3 Q14574,Q02487 2 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.7566782113877386 1.5759484174563274 0.1150376913920929 1.0 0.2876301974814571 5 Q15375 1 +Peptidase M28 [IPR007484] 0.9309619281054144 1.5523839162587718 0.1205703895556391 1.0 0.2952634873118096 3 P02786 1 +CALCOCO1/2, zinc finger UBZ1-type [IPR041641] 0.9207200103636128 1.5154726355603805 0.129652755085303 1.0 0.3083700453804885 3 Q86VP1 1 +SKICH domain [IPR041611] 0.9207200103636128 1.5154726355603805 0.129652755085303 1.0 0.3083700453804885 3 Q86VP1 1 +Cyclic nucleotide-binding domain [IPR000595] 0.7323219768378323 1.4801803391524362 0.1388251258697379 1.0 0.3208584075261141 5 Q6P4Q7,Q9Y4G8,P10644 3 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3305304423235011 3 O00754 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3305304423235011 3 O00754 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3305304423235011 3 O00754 1 +EH domain-containing protein, N-terminal [IPR031692] 0.8775995246583492 1.417417377806479 0.1563609348906616 1.0 0.3421559774612969 2 Q9H4M9 1 +Domain of unknown function DUF5600 [IPR040990] 0.8775995246583492 1.417417377806479 0.1563609348906616 1.0 0.3421559774612969 2 Q9H4M9 1 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.8910296766605521 1.4084443137031335 0.1589995452904635 1.0 0.3467641022207334 3 P39687 1 +Phox homology [IPR001683] 0.5872170436104965 1.3848335539284429 0.1661033683751847 1.0 0.3562058922203055 12 Q9UMY4,Q13596,O95219,O60749,Q96L92,O60493,Q9Y2I1 7 +FCH domain [IPR001060] 0.8669043374925729 1.3750703344448734 0.169109640353775 1.0 0.3600440951890651 2 Q9UNF0 1 +F-BAR domain [IPR031160] 0.8669043374925729 1.3750703344448734 0.169109640353775 1.0 0.3600440951890651 2 Q9UNF0 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7531433559077395 1.365327001534723 0.1721502960150664 1.0 0.3652005676493419 4 Q6PK18,Q32P28 2 +EF-hand domain [IPR002048] 0.4503656303028474 1.3348885195197169 0.1819128357871196 1.0 0.377671335790139 47 P80303,O75071,O43852,Q0IIM8,O95302,Q14257,Q7L5N7,P41208,Q02818,P42566,Q9H223,Q9H4M9 12 +YTH domain [IPR007275] 0.7396115139035017 1.313828242912093 0.1889040109294137 1.0 0.3901278486585719 4 Q7Z739 1 +Ras-associating (RA) domain [IPR000159] 0.7388273154162723 1.310844798381473 0.1899102038862197 1.0 0.3914959482907504 4 Q9Y4G8 1 +BSD domain [IPR005607] 0.8392751039809869 1.2660651179856923 0.2054897697421724 1.0 0.4106316053088562 2 P32780 1 +Major facilitator superfamily domain [IPR020846] 0.6765001123530926 1.2598080375515344 0.2077386195978203 1.0 0.411654590444384 5 Q7L0J3,Q9H2V7 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.6013910996420667 1.2595147182762143 0.2078444774258214 1.0 0.411654590444384 9 Q13308,Q15375,P29317,Q13418 4 +EH domain [IPR000261] 0.6760977950498186 1.2582194945311298 0.2083123866107423 1.0 0.4122849318337609 5 P42566,Q9H223,Q9H4M9 3 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6359430218284742 1.2573547047370657 0.208625223187826 1.0 0.4123116857119518 7 Q6PK18,Q32P28 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6359430218284742 1.2573547047370657 0.208625223187826 1.0 0.4123116857119518 7 Q6PK18,Q32P28 2 +CTP synthase GATase domain [IPR033828] 0.8330362448009515 1.2415575547866584 0.2143998504598239 1.0 0.4204068242112561 2 Q9NRF8 1 +CTP synthase, N-terminal [IPR017456] 0.8330362448009515 1.2415575547866584 0.2143998504598239 1.0 0.4204068242112561 2 Q9NRF8 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.670234909307159 1.2350758319515065 0.2168022830643554 1.0 0.4236101346399285 5 Q15019,Q16181,Q9NVA2,Q9UHD8 4 +THIF-type NAD/FAD binding fold [IPR000594] 0.5897519155522836 1.2080102654840548 0.2270433137604857 1.0 0.4319781280456755 9 Q8TBC4,O95396,Q9UBT2,O95352,Q13564 5 +GRAM domain [IPR004182] 0.7113045963395583 1.206292939037412 0.2277045592599988 1.0 0.4326386625939979 4 Q0IIM8,Q969T9 2 +bMERB domain [IPR022735] 0.8226381461675618 1.2008243265733405 0.2298193533195012 1.0 0.4342608493794415 2 Q8N3F8 1 +Sterile alpha motif domain [IPR001660] 0.5557504618423532 1.19251988031127 0.2330574602967741 1.0 0.4392244172999919 11 Q9Y3Z3,Q15375,P29317 3 +Rpn11/EIF3F, C-terminal [IPR024969] 0.705299326119281 1.1835411602988364 0.2365947439581004 1.0 0.4434659121964879 4 P51665,Q7L5N1 2 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.8149138443256119 1.1706689908640917 0.2417318541528428 1.0 0.4491769619839165 2 P24534 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.8149138443256119 1.1706689908640917 0.2417318541528428 1.0 0.4491769619839165 2 P24534 1 +Ion transporter-like, CBS domain [IPR044751] 0.8119429590017861 1.159096868588288 0.2464167021595433 1.0 0.4544029547855033 2 Q8NE01 1 +CNNM, transmembrane domain [IPR002550] 0.8119429590017861 1.159096868588288 0.2464167021595433 1.0 0.4544029547855033 2 Q8NE01 1 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.5939029264297825 1.1524976880665787 0.2491166192369074 1.0 0.457849423614196 8 P49459,Q9C0C9,P61088 3 +Sorting nexin, N-terminal [IPR005329] 0.8083778966131925 1.145230773352798 0.2521135738867821 1.0 0.4604439371044874 2 O60749 1 +Tudor domain [IPR002999] 0.5865752393867362 1.121178183231689 0.2622120243203916 1.0 0.4703654191476235 8 Q14739 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.5660406449522927 1.1030820092567024 0.2699915528538361 1.0 0.4789611900272495 9 O15400,Q9UNK0,Q9UEU0,Q86Y82,P56962 5 +Actin-depolymerising factor homology domain [IPR002108] 0.557559087303917 1.0656001876401626 0.2866044143576611 1.0 0.4977866969294168 9 Q9UJU6,P23528,Q6IBS0,P60983 4 +Fxr1, tudor domain [IPR041560] 0.7925107967004749 1.0565128573845577 0.2907339698497897 1.0 0.5005091697634706 3 Q06787 1 +Agenet-like domain [IPR008395] 0.7925107967004749 1.0565128573845577 0.2907339698497897 1.0 0.5005091697634706 3 Q06787 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7925107967004749 1.0565128573845577 0.2907339698497897 1.0 0.5005091697634706 3 Q06787 1 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7925107967004749 1.0565128573845577 0.2907339698497897 1.0 0.5005091697634706 3 Q06787 1 +Translation initiation factor IF2/IF5 domain [IPR002735] 0.7789661319073146 1.0318361892084682 0.3021488628855848 1.0 0.511943491543534 2 P55010 1 +THUMP domain [IPR004114] 0.7718360071301279 1.0046634408395947 0.3150589378284389 1.0 0.525098229714065 2 Q9NXG2 1 +Domain of unknown function DUF1747 [IPR013719] 0.7679738562091536 0.990004942235752 0.3221717033581122 1.0 0.5326579490376703 2 Q08945 1 +Rab-GTPase-TBC domain [IPR000195] 0.530770422025719 0.9476835419681328 0.343290581908465 1.0 0.5548313581233851 9 Q0IIM8,O60343,Q9BXI6,Q8TC07,Q4KMP7 5 +BRO1 domain [IPR004328] 0.7566844919786133 0.9474193516688588 0.3434251340036613 1.0 0.5548313581233851 2 Q5VW32 1 +NudC N-terminal domain [IPR025934] 0.7525252525252563 0.9318353300937612 0.3514216330270012 1.0 0.5622282426683971 2 Q8IVD9 1 +EB1, C-terminal [IPR004953] 0.7513368983957258 0.9273937795205808 0.3537221191746305 1.0 0.562381182331094 2 Q15691 1 +Zinc finger, LIM-type [IPR001781] 0.5123227446177693 0.9244616863622336 0.355245990572993 1.0 0.5627962645362827 10 Q14847,Q9UGI8,Q16527,Q8N3F8,Q13642 5 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.7462863933452211 0.9085737885569206 0.3635751476354345 1.0 0.5712161428104541 2 P43246 1 +Brdt, bromodomain, repeat II [IPR043509] 0.7451319399807046 0.8923831137931704 0.3721876189492819 1.0 0.5784379305700689 3 Q15059 1 +Brdt, bromodomain, repeat I [IPR043508] 0.7451319399807046 0.8923831137931704 0.3721876189492819 1.0 0.5784379305700689 3 Q15059 1 +NET domain [IPR027353] 0.7451319399807046 0.8923831137931704 0.3721876189492819 1.0 0.5784379305700689 3 Q15059 1 +CAP Gly-rich domain [IPR000938] 0.7446946597910712 0.8908949322499655 0.3729855392889947 1.0 0.5792419169905189 3 Q99426 1 +Syntaxin, N-terminal domain [IPR006011] 0.7444279346211005 0.8899874748898866 0.3734726115298714 1.0 0.5793451828630607 3 Q86Y82,O15400 2 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.7385620915032746 0.879975811225983 0.3788724134276942 1.0 0.5827992735864308 2 Q13526 1 +Butyrophylin-like, SPRY domain [IPR003879] 0.6177324667480597 0.8579430803895368 0.3909238943114825 1.0 0.5914307132499366 4 Q12899,O15344 2 +SPRY-associated [IPR006574] 0.6177324667480597 0.8579430803895368 0.3909238943114825 1.0 0.5914307132499366 4 Q12899,O15344 2 +Gamma-glutamyl cyclotransferase-like [IPR013024] 0.7323232323232367 0.8570514790127471 0.3914164349598337 1.0 0.5917511141338619 2 Q8WUX2 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.5710148698929614 0.849374267985135 0.3956730668408825 1.0 0.5941834059102313 5 P10586 1 +Nucleoside phosphorylase domain [IPR000845] 0.7254901960784361 0.8321341851742442 0.4053332079046619 1.0 0.6000499665649347 2 P00491 1 +SKP1 component, POZ domain [IPR016073] 0.7245989304812883 0.8288994021353226 0.4071613337223687 1.0 0.60081166564043 2 P63208 1 +Rho GTPase-activating protein domain [IPR000198] 0.5268277351722146 0.8108246603766472 0.4174663705738504 1.0 0.6101340581826958 7 Q9H0H5,P11274,O00459,Q07960 4 +HDGF-related, PWWP domain [IPR035496] 0.7207822014179028 0.810449967859334 0.4176816093403137 1.0 0.6101340581826958 3 Q7Z4V5 1 +Heat shock chaperonin-binding [IPR006636] 0.601664684898921 0.8003197844884783 0.4235255431374747 1.0 0.6156060784968427 4 P54727,P54725,Q9NRR5 3 +ABC transporter-like, ATP-binding domain [IPR003439] 0.4582371195532446 0.7909813057477627 0.4289549005260773 1.0 0.6206779154145708 13 P08183,Q9NUQ8,P33527 3 +Peptidase M16, N-terminal [IPR011765] 0.5207131330141666 0.7865268625613832 0.4315588879614431 1.0 0.6230983133557372 7 Q10713 1 +Peptidase M16, C-terminal [IPR007863] 0.5207131330141666 0.7865268625613832 0.4315588879614431 1.0 0.6230983133557372 7 Q10713 1 +eRF1 domain 3 [IPR005142] 0.7121212121212176 0.7840059558689889 0.4330366155792911 1.0 0.6235648426571433 2 Q9BRX2 1 +eRF1 domain 2 [IPR005141] 0.7121212121212176 0.7840059558689889 0.4330366155792911 1.0 0.6235648426571433 2 Q9BRX2 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.7121212121212176 0.7840059558689889 0.4330366155792911 1.0 0.6235648426571433 2 Q9BRX2 1 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.5175684615568281 0.7740840800054961 0.4388810712751327 1.0 0.6268104465334322 7 P25788,P60900 2 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.7058222569928634 0.7611752459326236 0.4465524015155293 1.0 0.6289631217665048 3 Q8TEY7 1 +FAD/NAD(P)-binding domain [IPR023753] 0.5459024883814788 0.7556125165533245 0.4498815492758772 1.0 0.6326818112583164 5 Q16881,O95831 2 +LIS1 homology motif [IPR006594] 0.4848863897616551 0.7491874394950139 0.4537442386185648 1.0 0.6368137429414906 9 Q9Y4B6,P43034 2 +CRK, C-terminal SH3 domain [IPR035458] 0.6960784313725548 0.7274600119097622 0.4669442031732873 1.0 0.6470982292466835 2 P46108 1 +CRK, N-terminal SH3 domain [IPR035457] 0.6960784313725548 0.7274600119097622 0.4669442031732873 1.0 0.6470982292466835 2 P46108 1 +Phosphoribosyltransferase domain [IPR000836] 0.4989853889857121 0.7013916160998661 0.4830586526838591 1.0 0.6577043620405548 7 Q9NRG1,P00492,P07741 3 +COMM domain [IPR017920] 0.6883541295306064 0.7007540169834621 0.4834565392016128 1.0 0.6577043620405548 2 Q9UBI1 1 +Methyltransferase type 11 [IPR013216] 0.685586924219912 0.6960471669068742 0.4863992917722091 1.0 0.6594496745777784 3 Q6FI81,Q8N6R0 2 +GTP binding protein, second domain [IPR031662] 0.6868686868686931 0.6956596044560157 0.4866420290449387 1.0 0.6594496745777784 2 P55039 1 +FYVE zinc finger [IPR000306] 0.5277993710021855 0.6897270205206822 0.4903658702947548 1.0 0.6608596829511117 5 O14964,Q96T51 2 +Zinc finger, FYVE-related [IPR017455] 0.5277993710021855 0.6897270205206822 0.4903658702947548 1.0 0.6608596829511117 5 O14964,Q96T51 2 +ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.6850861556743973 0.6895644153486201 0.4904681517157745 1.0 0.6608596829511117 2 Q14240 1 +Deoxynucleoside kinase domain [IPR031314] 0.6809269162210403 0.6754205597730158 0.4994086067951673 1.0 0.6672505876433976 2 O95299 1 +Legume-like lectin [IPR005052] 0.6800356506238925 0.6724042293104292 0.5013263910709989 1.0 0.668516073281995 2 Q12907 1 +PSI domain [IPR016201] 0.675652736397587 0.6647949154717924 0.5061816751913848 1.0 0.6733609440619339 3 P05556 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.6752822341057703 0.6564056308470542 0.5115631684108033 1.0 0.6746560693976845 2 Q96CW5 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.6752822341057703 0.6564056308470542 0.5115631684108033 1.0 0.6746560693976845 2 Q96CW5 1 +PPM-type phosphatase domain [IPR001932] 0.6687123320905537 0.6432698323506651 0.5200490277241256 1.0 0.6792053285611889 3 Q9H0C8 1 +Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.670528817587648 0.6405598507612354 0.5218086918914795 1.0 0.6806737434474555 2 Q16512 1 +Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.670528817587648 0.6405598507612354 0.5218086918914795 1.0 0.6806737434474555 2 Q16512 1 +Transcription factor IIS, N-terminal [IPR017923] 0.5530813832128719 0.6330240926504889 0.5267179099390078 1.0 0.6841988968709912 4 Q96ST2 1 +W2 domain [IPR003307] 0.4810962871002116 0.6330082608015727 0.5267282484677676 1.0 0.6841988968709912 7 P55010 1 +GTPase effector domain [IPR020850] 0.6660724896019086 0.6258478593756066 0.531414736869972 1.0 0.6876691404775823 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.6660724896019086 0.6258478593756066 0.531414736869972 1.0 0.6876691404775823 2 O00429 1 +Dynamin GTPase effector [IPR003130] 0.6660724896019086 0.6258478593756066 0.531414736869972 1.0 0.6876691404775823 2 O00429 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.5080299695539584 0.619809447188522 0.5353832482066667 1.0 0.6908575404259328 5 Q9UMX5 1 +Phosphofructokinase domain [IPR000023] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.6976585927061947 3 Q01813,P08237 2 +ABC transporter type 1, transmembrane domain [IPR011527] 0.4473343184856649 0.5930288962726052 0.5531618139435797 1.0 0.6981038925398818 9 P08183,P33527 2 +PABP, RNA recognition motif 2 [IPR045305] 0.6515151515151592 0.5788099338201175 0.5627174275361944 1.0 0.7045013549123073 2 Q13310 1 +Citron homology (CNH) domain [IPR001180] 0.6506238859180111 0.5759831313389928 0.5646265835275188 1.0 0.7064242677649021 2 Q8WUH2 1 +I/LWEQ domain [IPR002558] 0.6485442661913328 0.569411974412891 0.5690765924623049 1.0 0.7098267279731403 2 Q9Y490 1 +Chromo shadow domain [IPR008251] 0.6439821693907888 0.5688497690678098 0.5694580962693152 1.0 0.7098267279731403 3 P83916,Q13185 2 +Chromo domain subgroup [IPR017984] 0.6439821693907888 0.5688497690678098 0.5694580962693152 1.0 0.7098267279731403 3 P83916,Q13185 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7098683751205813 3 P43246 1 +DNA mismatch repair protein MutS, core [IPR007696] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7098683751205813 3 P43246 1 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7098683751205813 3 P43246 1 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7098683751205813 3 P43246 1 +High mobility group box domain [IPR009071] 0.4141115960679515 0.5583156539939277 0.5766288573791356 1.0 0.713563545024661 12 O15347,P09429,O96028,P26583,O94842 5 +WH2 domain [IPR003124] 0.6399286987522362 0.5425661500723199 0.5874285504886607 1.0 0.7202339370699868 2 Q9Y6W5 1 +Arf GTPase activating protein [IPR001164] 0.6335809806835078 0.5387157279212308 0.5900830196345177 1.0 0.7228451396590023 3 Q8N6T3,Q8IYB5 2 +HECT domain [IPR000569] 0.4117242805804325 0.489561728598693 0.6244440638149236 1.0 0.7521206894864209 10 Q96PU5,Q96J02,P46934 3 +U-box domain [IPR003613] 0.4379648914013793 0.476788967480111 0.6335124026143579 1.0 0.7578491833272063 7 Q9UMS4,P19474,Q14139,O95155,Q13356,Q9UNE7 6 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5027455798706593 0.4752279596871497 0.6346245004503179 1.0 0.7588500428561744 4 O60749,Q13596 2 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.6056463595839536 0.4616637248527641 0.6443224885061183 1.0 0.7628905606135092 3 P28340,P09884 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.6056463595839536 0.4616637248527641 0.6443224885061183 1.0 0.7628905606135092 3 P28340,P09884 2 +WHEP-TRS domain [IPR000738] 0.4971097454434453 0.458833070407933 0.6463540445590688 1.0 0.7645793871877349 4 P41250 1 +VHS domain [IPR002014] 0.4493012191495775 0.4289581560991757 0.6679536764307057 1.0 0.7860796149366058 5 Q6ZVM7,O75886,Q9UJY4,O14964 4 +Kinesin-like [IPR022164] 0.5962566844919881 0.4168690647648611 0.6767741820028217 1.0 0.7922587859372716 2 Q9Y3P9 1 +Kinesin-associated [IPR032405] 0.5962566844919882 0.4168690647648604 0.6767741820028221 1.0 0.7922587859372716 2 Q15058 1 +RNA-binding S4 domain [IPR002942] 0.593879976232927 0.4105741639047972 0.6813848115559265 1.0 0.7957673403291977 2 P46781 1 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.4415700267618289 0.4061778492683345 0.6846119283406815 1.0 0.7988588998638617 5 P62195,P17980,P62333,P62191 4 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.4731669109740725 0.3925560028681317 0.6946474406693148 1.0 0.8048478651848103 4 Q9NRF9 1 +14-3-3 domain [IPR023410] 0.4191461236081376 0.3924702498270574 0.6947107888963626 1.0 0.8048478651848103 6 P27348,P62258,P63104 3 +Dynamin, N-terminal [IPR045063] 0.4105024313141335 0.3857585702858221 0.6996754809215906 1.0 0.8085619461519468 7 Q9H223,Q9H4M9 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.4105024313141335 0.3857585702858221 0.6996754809215906 1.0 0.8085619461519468 7 Q9H223,Q9H4M9 2 +B-box, C-terminal [IPR003649] 0.4640309155766813 0.3688096043082685 0.7122696453758028 1.0 0.8151438072907786 4 Q9UPN9,O15344,Q13263 3 +MCM, AAA-lid domain [IPR041562] 0.4049390062481496 0.3682970072430748 0.7126517838179218 1.0 0.8151438072907786 7 Q9UJA3,P49736,P33991,P33992,P25205,P33993 6 +MCM domain [IPR001208] 0.4049390062481496 0.3682970072430748 0.7126517838179218 1.0 0.8151438072907786 7 Q9UJA3,P49736,P33991,P33992,P25205,P33993 6 +MCM OB domain [IPR033762] 0.4049390062481496 0.3682970072430748 0.7126517838179218 1.0 0.8151438072907786 7 Q9UJA3,P49736,P33991,P33992,P25205,P33993 6 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.5667391408502666 0.3651203398995752 0.7150215784537803 1.0 0.8160250408617087 3 Q13310 1 +Exportin-2, central domain [IPR013713] 0.5659867763417205 0.3633899430469933 0.7163136133466508 1.0 0.8166475027582647 3 O95373 1 +MCM N-terminal domain [IPR027925] 0.4048185603807373 0.3499470661054144 0.7263784238826794 1.0 0.8255662367148439 6 P49736,P33991,P33992,P25205,P33993 5 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.5545319465081738 0.3377252484414867 0.7355702460644142 1.0 0.8336059349681042 3 P47897,P07814 2 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.5623885918003664 0.3330871576294195 0.739068493148757 1.0 0.8368819147656497 2 P07814 1 +Glycogen synthase kinase 3, catalytic domain [IPR039192] 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.8430782868107517 2 P49840 1 +Cyclin-like [IPR013763] 0.5405646359583969 0.3082061343805286 0.7579254849659265 1.0 0.8550715442592659 3 P14635,P06400 2 +EF-hand, Ca insensitive [IPR014837] 0.5372919493307942 0.3015788122605863 0.7629731617587177 1.0 0.8551314798076552 3 O43707 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.434943145761537 0.2994468845206938 0.7645990936153784 1.0 0.855593218078947 4 P61970 1 +Nuclear transport factor 2 domain [IPR002075] 0.434943145761537 0.2994468845206938 0.7645990936153784 1.0 0.855593218078947 4 P61970 1 +Enolase, C-terminal TIM barrel domain [IPR020810] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.8567814585461844 2 P09104 1 +Enolase, N-terminal [IPR020811] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.8567814585461844 2 P09104 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.8605714849281234 2 P22314 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.8605714849281234 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.8605714849281234 2 P22314 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.8605714849281234 2 P22314 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.5260029717682038 0.2795790358827167 0.7798004928821036 1.0 0.867319482394104 3 Q10567,O00203 2 +GYF domain [IPR003169] 0.53565062388593 0.2764732789459116 0.7821845804262311 1.0 0.8689187576912365 2 O95400 1 +Staufen, C-terminal [IPR032478] 0.5227340267459154 0.2734605101386073 0.7844992441717673 1.0 0.8707878395218449 3 Q9NUL3,O95793 2 +Sec23, C-terminal [IPR037550] 0.5338680926916342 0.273011771811604 0.7848441666091031 1.0 0.8708198465598385 2 Q15437 1 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.5306001188354252 0.2667686053605342 0.7896473277992033 1.0 0.8743884196490375 2 Q9HC38 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4192589875838935 0.2662505574321748 0.7900462485279172 1.0 0.8744786720347174 4 P08238 1 +SGS domain [IPR007699] 0.5300059417706552 0.2656478174604489 0.7905104552745026 1.0 0.8746410860567287 2 Q9HB71 1 +TOG domain [IPR034085] 0.372613869465431 0.2636939296164367 0.7920157734943367 1.0 0.8749011451390929 6 Q8TEX9 1 +HR1 rho-binding domain [IPR011072] 0.4170630202140187 0.2618481813961977 0.7934384912233305 1.0 0.8761214602486075 4 Q16512,O75116,Q16513 3 +Chaperone DnaJ, C-terminal [IPR002939] 0.3850728516205828 0.2609168781899555 0.7941566086499694 1.0 0.8762777349319247 5 P25685,Q9UBS4,O60884,P31689 4 +Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.5196078431372675 0.2467499090856318 0.805101778652388 1.0 0.887577190951312 2 Q9UKA9 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.5069836552748901 0.2455889938735746 0.8060004099668792 1.0 0.8876190566166415 3 P36871,O95394 2 +Importin-alpha, importin-beta-binding domain [IPR002652] 0.3742421704584036 0.2378167231813901 0.8120232475136102 1.0 0.8923510358595916 5 P52292,O60684 2 +Glutamine amidotransferase type 2 domain [IPR017932] 0.5004457652303137 0.2348084192763812 0.8143574327823149 1.0 0.8942027609865594 3 Q06210,P08243 2 +Zinc finger, double-stranded RNA binding [IPR022755] 0.401229083467043 0.231927632330881 0.8165942221159264 1.0 0.8959446761964863 4 Q9UKJ3,Q969S3 2 +Glutamine amidotransferase [IPR017926] 0.3989541742863032 0.2278941532952543 0.8197285281342526 1.0 0.896988230589647 4 Q9NRF8 1 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.5068330362448141 0.2253889677205628 0.821676693349386 1.0 0.8975889334566125 2 O95394 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845] 0.5068330362448088 0.2253889677205542 0.8216766933493926 1.0 0.8975889334566125 2 P36871 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846] 0.5068330362448088 0.2253889677205542 0.8216766933493926 1.0 0.8975889334566125 2 P36871 1 +Domain of unknown function DUF3517 [IPR021905] 0.5062388591800486 0.2244451639298781 0.8224109312303081 1.0 0.8977621840204746 2 Q9UPU5 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.4900445765230329 0.2186157617795893 0.8269493736595386 1.0 0.9004923021470469 3 Q7L576,Q96F07 2 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.4955436720142681 0.2082078229584225 0.8350667006040704 1.0 0.9075379724513664 2 O95336 1 +Translation initiation factor, beta propellor-like domain [IPR013979] 0.3864447086801351 0.2069144247991212 0.8360766909349937 1.0 0.9079193076570388 4 P55884,Q9BY44,Q96J01 3 +DALR anticodon binding [IPR008909] 0.4925727866904472 0.2039485388948706 0.8383937135932238 1.0 0.909360110609973 2 P54136 1 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.4925727866904472 0.2039485388948706 0.8383937135932238 1.0 0.909360110609973 2 P54136 1 +UBX domain [IPR001012] 0.3555100036918418 0.2017731176962551 0.8400940982612644 1.0 0.9106164708013664 5 Q04323 1 +Ubiquitin-associated domain [IPR015940] 0.3224903942660228 0.2004481013255252 0.8411301433379053 1.0 0.9106164708013664 13 Q14157,P45974,P54727,Q9Y5A7,Q04323 5 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.3387358978487889 0.1999310597846789 0.8415344986285036 1.0 0.9106164708013664 8 P10586,Q99956,P51452 3 +Gelsolin-like domain [IPR007123] 0.3438429506246201 0.1988753043324498 0.8423602879203576 1.0 0.911151391134898 6 Q15436,Q13045,P53992,O95487,Q15437 5 +B3/B4 tRNA-binding domain [IPR005146] 0.4863339275104045 0.1953556468874435 0.8451145362423558 1.0 0.9134133179080776 2 Q8N1G4 1 +Ubiquitin conjugation factor E4, core [IPR019474] 0.4842543077837333 0.1925964225278292 0.8472750468845018 1.0 0.9153893153595304 2 O95155 1 +CLASP N-terminal domain [IPR024395] 0.4797979797979905 0.186859009281024 0.851771178908584 1.0 0.9191655299228942 2 Q7Z460 1 +GOLD domain [IPR009038] 0.3355203118147209 0.1848048597391637 0.8533820959982223 1.0 0.9205433337803848 7 Q9H3P7 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.4647218096340544 0.1840866324466735 0.8539454930329624 1.0 0.92059507575651 3 Q08J23 1 +Sec23/Sec24 beta-sandwich [IPR012990] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.92059507575651 5 P53992,Q15436,O95487,Q15437 4 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.92059507575651 5 P53992,Q15436,O95487,Q15437 4 +Sec23/Sec24, trunk domain [IPR006896] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.92059507575651 5 P53992,Q15436,O95487,Q15437 4 +Sec23/Sec24, helical domain [IPR006900] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.92059507575651 5 P53992,Q15436,O95487,Q15437 4 +Dynamin, GTPase domain [IPR001401] 0.4627043090638948 0.1816301134158499 0.8558730148240916 1.0 0.92059507575651 3 O00429,P50570 2 +Ran binding domain [IPR000156] 0.3652570172819933 0.1760020601171713 0.8602923239733449 1.0 0.9236575808833069 4 Q9H6Z4 1 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.3392804044008437 0.1746173604478173 0.8613803065057746 1.0 0.9237457160075552 5 P62888,Q9NX24,P25398,P55769 4 +Histone deacetylase domain [IPR023801] 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.9254995910961104 2 Q92769 1 +SGNH hydrolase-type esterase domain [IPR013830] 0.4652406417112443 0.1697498402872916 0.8652068759426852 1.0 0.925687356591106 2 Q15102 1 +Gamma-adaptin ear (GAE) domain [IPR008153] 0.4490341753343256 0.1661013700274081 0.8680771760083028 1.0 0.9280374931714684 3 O43747,Q9UJY4 2 +AP complex, mu/sigma subunit [IPR022775] 0.3318465655664651 0.1634421904484288 0.8701702862992042 1.0 0.929553756787246 5 P53680,P61923,Q96CW1,P48444 4 +Cullin protein, neddylation domain [IPR019559] 0.3233194527067131 0.1602680803612778 0.8726699020032556 1.0 0.930512405806022 6 Q13619,Q93034,Q13620,Q13617,Q13618 5 +Cullin homology domain [IPR016158] 0.3233194527067131 0.1602680803612778 0.8726699020032556 1.0 0.930512405806022 6 Q13619,Q93034,Q13620,Q13617,Q13618 5 +Cullin, N-terminal [IPR001373] 0.3234156501041489 0.1601966482971961 0.8727261695698405 1.0 0.930512405806022 7 Q13619,Q93034,Q13620,Q13617,Q86Y37,Q13618 6 +LRRC8, pannexin-like TM region [IPR021040] 0.4551396316102327 0.1593006972153101 0.8734319714752716 1.0 0.930512405806022 2 Q8TDW0 1 +Zinc finger, UBP-type [IPR001607] 0.4413022225249552 0.1581616755924788 0.8743294020355512 1.0 0.931108427757226 3 Q8TEY7 1 +UAS [IPR006577] 0.4524658348187828 0.1567228636576379 0.8754632671560869 1.0 0.9317073103311004 2 Q9UNN5 1 +Thioesterase domain [IPR006683] 0.4500891265597251 0.1544960507847584 0.877218624853527 1.0 0.9320856343929004 2 O00154 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.449494949494958 0.1539487596296621 0.8776501377066168 1.0 0.9320856343929004 2 P35611 1 +N-terminal extension of GAT domain [IPR041198] 0.4489007724301992 0.1534052108710128 0.8780787358461806 1.0 0.9320856343929004 2 Q9UJY4 1 +PIN domain [IPR002716] 0.4486036838978133 0.1531348363470061 0.8782919444224935 1.0 0.9320856343929004 2 Q9ULX3 1 +tRNA-binding domain [IPR002547] 0.4477124183006621 0.1523292950750753 0.8789272204020557 1.0 0.9322573622376534 2 P54577 1 +KOW [IPR005824] 0.3202497769848452 0.1475735364893957 0.8826793412148723 1.0 0.9327892539497404 5 Q92917,O00267,P61353,P62701 4 +ERM family, FERM domain C-lobe [IPR041789] 0.340368608799038 0.1469208794416481 0.8831944713489663 1.0 0.9329757548184058 4 P35241,P26038,P15311 3 +TGS [IPR004095] 0.3135038667459759 0.1441010160052478 0.8854207024402723 1.0 0.934610741464732 6 Q9NTK5,P55039,P26639,Q9Y295,Q9BW92 5 +Anticodon-binding [IPR004154] 0.3353151010701486 0.141927792943085 0.8871370409397217 1.0 0.9360637869739308 4 P26639,P41250,P07814 3 +Mu homology domain [IPR028565] 0.3317479191438705 0.1385806973404583 0.8897814974038833 1.0 0.9384946498268372 4 Q9BXS5,P48444,Q96CW1 3 +E3 ligase, CCCH-type zinc finger [IPR041367] 0.4182268050289024 0.137908571393183 0.8903126761487479 1.0 0.938695531109759 3 Q86VM9 1 +GINS subunit, domain A [IPR021151] 0.4171010779028914 0.1370465321810009 0.8909940147114019 1.0 0.939054518182828 3 Q9BRT9 1 +IPT domain [IPR002909] 0.3282913612704727 0.1354748453381331 0.892236451400797 1.0 0.9400043684930004 4 Q9UIW2 1 +Exosome complex component, N-terminal domain [IPR025721] 0.4174093879976329 0.1296315119327599 0.8968579706815112 1.0 0.9433066880475224 2 Q9Y3B2 1 +ROCK, Rho binding domain [IPR015008] 0.4168152109328679 0.129271465895114 0.8971428488767188 1.0 0.9433066880475224 2 O75116 1 +FKBP3, basic tilted helix bundle domain [IPR041200] 0.4162210338680994 0.1289144452216496 0.897425346414721 1.0 0.9433066880475224 2 Q9ULT8 1 +NOPS [IPR012975] 0.4038632986627062 0.1277338377569098 0.89835961076944 1.0 0.9439285765331072 3 Q8WXF1,Q15233 2 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.3937592867756332 0.1215986549905461 0.9032168787472832 1.0 0.9477265188001968 3 P23193,Q14241 2 +DOCKER domain [IPR027357] 0.3934621099554254 0.1214303062569022 0.9033502135641804 1.0 0.9477265188001968 3 Q96HP0,Q14185 2 +C2 DOCK-type domain [IPR027007] 0.3934621099554254 0.1214303062569022 0.9033502135641804 1.0 0.9477265188001968 3 Q96HP0,Q14185 2 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.400475341651823 0.1205053647086975 0.9040828301926752 1.0 0.9477732865984856 2 O15160 1 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.400475341651823 0.1205053647086975 0.9040828301926752 1.0 0.9477732865984856 2 O15160 1 +Serpin domain [IPR023796] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.9479359255427924 2 P35237 1 +Dedicator of cytokinesis C, C2 domain [IPR037808] 0.3933452168746363 0.1173194535292192 0.90660690979568 1.0 0.9479359255427924 2 Q96HP0 1 +Dedicator of cytokinesis C/D, N-terminal [IPR021816] 0.3933452168746363 0.1173194535292192 0.90660690979568 1.0 0.9479359255427924 2 Q96HP0 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3848439821693926 0.1168352635780069 0.9069905988133578 1.0 0.9479359255427924 3 O60884,P31689 2 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.3835405607750695 0.1161873577420897 0.9075040559526996 1.0 0.94811288363659 3 Q9BYT8 1 +GAR domain [IPR003108] 0.3877005347593669 0.1150478641102014 0.908407183812769 1.0 0.948696660881038 2 Q03001 1 +Dual specificity protein phosphatase domain [IPR020422] 0.2948870392389945 0.111910553742472 0.9108943284965604 1.0 0.9495549728481276 4 Q8WUK0,Q99956,P51452 3 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.2948870392389945 0.111910553742472 0.9108943284965604 1.0 0.9495549728481276 4 Q8WUK0,Q99956,P51452 3 +SH2 domain [IPR000980] 0.2942729842505059 0.1118373464953789 0.9109523750408716 1.0 0.9495549728481276 13 P62993,O00459 2 +Dilute domain [IPR002710] 0.3758169934640591 0.1109285214004649 0.9116730283650056 1.0 0.9499467447600568 2 Q9Y4I1 1 +Ubiquitin system component CUE [IPR003892] 0.3652303120356633 0.1082937477694595 0.9137626820074664 1.0 0.9506796293797568 3 Q9H4L7,Q9H1I8 2 +Ribosomal protein L11, N-terminal [IPR020784] 0.3657159833630494 0.1080621065170561 0.9139464267015992 1.0 0.9506796293797568 2 P30050 1 +Ribosomal protein L11, C-terminal [IPR020783] 0.3657159833630494 0.1080621065170561 0.9139464267015992 1.0 0.9506796293797568 2 P30050 1 +Plectin/S10, N-terminal [IPR005326] 0.3645276292335189 0.1077596812035043 0.914186326328045 1.0 0.9506796293797568 2 P46783 1 +DNA ligase, ATP-dependent, N-terminal [IPR012308] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9508721066197338 2 P18858 1 +DNA ligase, ATP-dependent, central [IPR012310] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9508721066197338 2 P18858 1 +DNA ligase, ATP-dependent, C-terminal [IPR012309] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9508721066197338 2 P18858 1 +Ribosomal protein S7 domain [IPR023798] 0.346405228758178 0.1039424636939488 0.9172150084414183 1.0 0.9509185087321064 2 P46782 1 +ENTH domain [IPR013809] 0.3459138187221419 0.1021311669799864 0.91865256268088 1.0 0.9509185087321064 3 O00291,Q14677 2 +Sec24-like, trunk domain [IPR041742] 0.3435364041604773 0.101505923994953 0.9191488551822288 1.0 0.9509185087321064 3 P53992,O95487 2 +Inositol polyphosphate-related phosphatase [IPR000300] 0.3279857397504543 0.1013316955207456 0.9192871562925048 1.0 0.9509185087321064 2 Q01968 1 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.32412358882948 0.1009136852659135 0.9196189792964826 1.0 0.9509185087321064 2 P49588 1 +26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.3226381461675669 0.1007632364478062 0.9197384113232836 1.0 0.9509185087321064 2 Q15008 1 +BAT2, N-terminal [IPR009738] 0.3399702823179812 0.10061760577879 0.9198540202435804 1.0 0.9509185087321064 3 Q9Y520,Q5JSZ5 2 +Rhodanese-like domain [IPR001763] 0.2649420160570985 0.0961405683391025 0.9234089316417632 1.0 0.9533686002418884 5 Q99956,O95396,P25325,P40818 4 +Longin domain [IPR010908] 0.2906389301634494 0.0931305172320514 0.9257998735398956 1.0 0.954915257058185 3 O15498,P51809 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.2906389301634494 0.0931305172320514 0.9257998735398956 1.0 0.954915257058185 3 O15498,P51809 2 +Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.2336504161712204 0.09196852541357 0.9267230466616592 1.0 0.9555097281260744 4 P14868,O43776,Q15046 3 +La-type HTH domain [IPR006630] 0.2543478846414809 0.090263456077244 0.9280778593965062 1.0 0.9565486354797512 5 P05455,Q6PKG0,Q92615 3 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.2337198929527262 0.0816813559967041 0.9349001045704604 1.0 0.9622589330860564 5 P14868,O43776,Q15046,P27694 4 +K Homology domain, type 1 [IPR004088] 0.2968546751205376 0.0674094631294904 0.9462557358385496 1.0 0.970925345338996 25 Q8IWZ3,Q9Y2W6,O75179,Q9Y6M1,Q06787,Q96AE4,P51114 7 +Ubiquitin specific protease domain [IPR028889] 0.2718202464043043 0.0369280767693958 0.9705423529856942 1.0 0.990867125522739 15 Q8TEY7,P54578,Q96K76,P45974,P51784 5 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.2718202464043043 0.0369280767693958 0.9705423529856942 1.0 0.990867125522739 15 Q8TEY7,P54578,Q96K76,P45974,P51784 5 +Aminoacyl-tRNA synthetase, class II [IPR006195] 0.2341376228775751 0.0113752210780737 0.990924082457223 1.0 1.0 11 P14868,Q9Y285,P49591,Q9NP81,P07814,P41250,O43776,Q15046,P26639,Q9BW92 10 +CS domain [IPR007052] 0.2263026058206612 0.0077855790719914 0.9937880694178902 1.0 1.0 10 Q9Y266,Q15185,Q8IVD9,Q8WVJ2,Q96RS6 5 +Ubiquitin-like domain [IPR000626] 0.2644975240608673 0.0075961715876254 0.9939391902557086 1.0 1.0 16 Q8WVY7,Q8NCF5,Q99426 3 +SH3 domain [IPR001452] 0.2871946953672037 0.0005982613772383 0.9995226565122516 1.0 1.0 39 Q9UKS6,Q14247,Q14847,Q9UJU6,Q9UQB8,P62993,P46108,Q9UNF0,O00459,Q14168 10 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0b4e842a7bcf238dd9ad4fdd39fa7d5f513da713 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AF-9, ANC1 homology domain [IPR040930]", "AF4/FMR2, C-terminal homology domain [IPR043640]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-dystroglycan N-terminal domain 2 [IPR041631]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 13, N-terminal [IPR018731]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF1, PHD domain [IPR042008]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DG-type SEA domain [IPR030398]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disintegrin domain [IPR001762]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "Dystroglycan, C-terminal [IPR008465]", "Dystroglycan-type cadherin-like [IPR006644]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 2, ligand binding domain [IPR034263]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPCR, family 2-like [IPR017981]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GPS motif [IPR000203]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galanin [IPR008174]", "Galanin message associated peptide (GMAP) [IPR013068]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "ITPR-interacting domain [IPR029325]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR14, PH-GRAM domain [IPR039803]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial ABC-transporter, N-terminal five TM domain [IPR032410]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MnmG, N-terminal domain [IPR040131]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Neogenin, C-terminal [IPR010560]", "Net1, PH domain [IPR037853]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Peregrin, ePHD domain [IPR042061]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Protocadherin [IPR013585]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Putative zinc-finger domain [IPR019607]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM40, RNA recognition motif 1 [IPR034147]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RING1 , RING finger, HC subclass [IPR042741]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad4 beta-hairpin domain 1 [IPR018326]", "Rad4 beta-hairpin domain 2 [IPR018327]", "Rad4 beta-hairpin domain 3 [IPR018328]", "Rad4/PNGase transglutaminase-like fold [IPR018325]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM2, SH3 domain [IPR035675]", "STAR protein, homodimerisation region [IPR032377]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Sperm-specific antigen 2, C-terminal [IPR029326]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 131-like, N-terminal [IPR022113]", "Transmembrane protein 131-like, conserved domain [IPR045695]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZZ3, zinc finger, ZZ-type [IPR041981]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal [IPR026904]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARMC10", "ARMCX3", "ARMT1", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BROX", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNPY2", "COA3", "COASY", "COG2", "COG4", "COIL", "COLEC12", "COMMD3", "COMMD4", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAG1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCK", "DCP1B", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMB", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FANCA", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GAL", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA4", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KIRREL1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LRSAM1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYRM7", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAK16", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED25", "METAP2", "METTL13", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGA", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NEMF", "NENF", "NEO1", "NES", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRP1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAI1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RING1", "RIOX1", "RIPK1", "RMND1", "RNASEH2A", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPPL2A", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSFA2", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK3", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STRN4", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIMELESS", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM131", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBLCP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGGT2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRNIP1", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB33", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX", "ZZZ3"], "leading_proteins": ["AARS", "ABCB1", "ABCC1", "ABCF3", "ACBD3", "ACOT7", "ACTN4", "ADD1", "ADGRE5", "AIFM1", "AIP", "ALCAM", "ANKHD1", "ANKRD17", "ANP32A", "AP1B1", "AP1G1", "AP1M1", "AP2M1", "AP2S1", "AP3B1", "APLP2", "APRT", "ARCN1", "ARFGAP1", "ARHGAP1", "ASCC2", "ASNS", "ATG7", "BAIAP2", "BCR", "BRD3", "BROX", "BSG", "CACUL1", "CACYBP", "CALU", "CBX1", "CBX3", "CCNB1", "CD2BP2", "CETN2", "CFL1", "CHAC2", "CIAPIN1", "CLASP1", "CLCN3", "CLCN7", "CLINT1", "CNNM3", "CNNM4", "COLEC12", "COMMD3", "COPS6", "COPZ1", "CRK", "CSRP2", "CTPS2", "CTTN", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYFIP1", "CYFIP2", "DARS", "DBNL", "DCAF1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNM1L", "DNM2", "DOCK1", "DOCK6", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DUSP3", "DUSP9", "EEF1B2", "EFCAB14", "EHD1", "EHD4", "EIF2A", "EIF3B", "EIF4A2", "EIF5", "ELOA", "EMB", "ENO2", "EPHA2", "EPHA7", "EPRS", "EPS15", "EXOSC1", "EZR", "F11R", "FAF1", "FARSA", "FAT1", "FCGRT", "FHL1", "FKBP9", "FLII", "FMR1", "FUBP1", "FUCA2", "FXR1", "GARS", "GFPT1", "GGA2", "GINS4", "GLB1", "GLOD4", "GMFB", "GPATCH8", "GPKOW", "GRB2", "GSK3A", "GTF2H1", "HDAC2", "HDGFL2", "HECTD1", "HEXA", "HGS", "HIP1", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGB3", "HPRT1", "HSP90AB1", "IGF2BP2", "IGF2R", "ILK", "ILKAP", "IPO4", "IPO7", "ITCH", "ITGB1", "IWS1", "KARS", "KIF14", "KPNA2", "KPNA6", "LAMB1", "LARP1", "LARP4B", "LASP1", "LBR", "LDLR", "LIG1", "LMAN2", "LNPEP", "LPCAT2", "LRIG2", "LRP1", "LRRC47", "LRRC8C", "M6PR", "MAN2B1", "MAPRE1", "MCAM", "MCM2", "MCM3", "MCM4", "MCM5", "MCM7", "MCM8", "METTL13", "MFGE8", "MICALL1", "MID1", "MOCS3", "MPP2", "MPST", "MRC2", "MSH2", "MSN", "MYO5A", "NAE1", "NARS", "NCAM1", "NDUFA10", "NECTIN2", "NEDD4", "NEDD4L", "NENF", "NEO1", "NFATC2IP", "NHP2", "NISCH", "NLN", "NOB1", "NONO", "NPC2", "NPEPPS", "NSD2", "NSUN2", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUTF2", "OCRL", "OGFOD3", "OLA1", "P3H1", "PABPC4", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PCDH7", "PDE6D", "PELO", "PFKM", "PFKP", "PGLS", "PGM1", "PGM3", "PIK3R2", "PIN1", "PKN1", "PKN2", "PLXNA1", "PMPCA", "PNP", "POLA1", "POLD1", "POLE3", "POLR1C", "PPIL2", "PRKAG1", "PRKAR1A", "PRPF19", "PRRC2B", "PRRC2C", "PRTFDC1", "PSMA3", "PSMA6", "PSMC1", "PSMC3", "PSMC5", "PSMC6", "PSMD6", "PSMD7", "PSPC1", "PTBP2", "PTGES3", "PTK7", "PTPMT1", "PTPRF", "QARS", "RABGAP1", "RACGAP1", "RAD23A", "RAD23B", "RANBP3", "RAPGEF2", "RARS", "RB1", "RCN2", "RDX", "ROBO1", "ROCK2", "RPA1", "RPL12", "RPL27", "RPL30", "RPS10", "RPS12", "RPS4X", "RPS5", "RPS9", "RUFY1", "SAMHD1", "SARS", "SARS2", "SEC23A", "SEC23B", "SEC24B", "SEC24C", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SEZ6L2", "SKP1", "SLIT2", "SMAP1", "SMARCAD1", "SNU13", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX4", "SPNS1", "SSB", "SSRP1", "STAM2", "STAU1", "STAU2", "STUB1", "STX12", "STX17", "STX7", "STX8", "SUPT5H", "SV2A", "TARS", "TARS2", "TAX1BP1", "TBC1D10A", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCB", "TCEA1", "TDRKH", "TENM3", "TES", "TFRC", "TGFBRAP1", "THOC3", "THUMPD1", "TLN1", "TOM1L2", "TOX4", "TPBG", "TRIM21", "TRIM26", "TRIM28", "TRIM33", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP3", "TWF2", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBAP2L", "UBE2A", "UBE2N", "UBE2O", "UBE4A", "UBE4B", "UBLCP1", "UBQLN4", "UBXN1", "USP11", "USP14", "USP24", "USP33", "USP47", "USP5", "USP8", "VAMP7", "VTI1B", "WASF2", "WBP2", "YARS", "YKT6", "YTHDF3", "YWHAE", "YWHAQ", "YWHAZ", "ZC3H18", "ZNF622"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d87ab8408793abe6737b70f108124c6686e8616f --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "ThiF/MoeB/HesA family [IPR045886]", "2": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "3": "26S proteasome regulatory subunit P45-like [IPR005937]", "4": "Mini-chromosome maintenance protein [IPR031327]", "5": "Cullin [IPR045093]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2538e75f9a231d8bd06b7e4e123ebe926ce93506 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0dbcd086b1619ae2c524bf5d3c35c2f5709567b236df78e6deeee5cda0c457e0 +size 130977 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 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sha256:59f40a9e00582bce1bdf72aee1a44a8f008076cf32cd9481713bd2846dfe91ce +size 145383 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..2cf76b98084dfb933db2845e35c17baa091acb82 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eae845f1df6e69861a30520c4794ce2c1bdfaae016d1c801a9c7dbafc1596795 +size 148136 diff --git a/interpro_family/basic/plot_5.png b/interpro_family/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6a852d6800743946bcf4d6993422487c3db2444b --- /dev/null +++ b/interpro_family/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe0ec103023338455b2d66e8dbe098ea2210ccd4acb8463f8dcfb61d592c5e0e +size 134178 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..611bd92a1fbe87d063bab851998ce2afec91db6d --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1b268dfb518a29d537c00a615a19dc74624e77728b1a199bdcbd825a5c12298 +size 460754 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..de00cfa49b17674e26dc04b984740d8ff67c2c1f --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 2 6 1.973040745678617 0.0484909202988617 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0633191306420368 0.0385773062479974 0.0758460972151271 0.0150927838189798 0.0053637976870067 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9dfe9062962e73369387453a05d52f08291f2b0e --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 2588, + "title": "Average number of proteins per term", + "value": 1.285548686244204 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1726df5b467b3db1c2249b99e7adc40b7d7233a7 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..84b0588768d3258e5632ea7a3c90d2227aebb595 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,148 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8287233876662697 1.973040745678617 0.0484909202988617 1.0 0.1368886089086385 6 P55786,Q9UIQ6 2 +Aminopeptidase N-type [IPR034016] 0.9132421652282796 1.9684274112865383 0.0490188805350446 1.0 0.1377425220680734 4 Q9UIQ6 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.9114149821640884 1.9616706453575312 0.049800841553117 1.0 0.1391842094378692 4 Q99733,Q01105,P55209 3 +Proteasome, subunit alpha/beta [IPR001353] 0.6760234570926145 1.9270990103167016 0.0539672920726794 1.0 0.146709403239595 14 P28070,P28074,Q99436,P25788,P28072,P60900,P49721 7 +Amyloidogenic glycoprotein [IPR008155] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.1575547129659648 2 Q06481 1 +Palmitoyl protein thioesterase [IPR002472] 0.9937611408199644 1.8776235142724296 0.0604326866440732 1.0 0.1579795889241024 2 Q9UMR5 1 +Proteasome B-type subunit [IPR023333] 0.7847520308122923 1.8648156771605808 0.0622072450648094 1.0 0.1605108177744036 7 P49721,P28070,P28074,P28072 4 +Glycoside hydrolase, family 29 [IPR000933] 0.9896019013666072 1.861234252074333 0.0627111033394731 1.0 0.1609999900707794 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9896019013666072 1.861234252074333 0.0627111033394731 1.0 0.1609999900707794 2 Q9BTY2 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.9789067142008324 1.819038463872372 0.0689055620861074 1.0 0.1706484159606182 2 P13473 1 +Glycoside hydrolase, family 35 [IPR001944] 0.977421271538919 1.81317233862047 0.0698052447719372 1.0 0.1720533080664511 2 P16278 1 +Beta-galactosidase 1-like [IPR026283] 0.977421271538919 1.81317233862047 0.0698052447719372 1.0 0.1720533080664511 2 P16278 1 +Beta-hexosaminidase [IPR025705] 0.9753416518122408 1.804957587878303 0.0710813190900347 1.0 0.1743682026587772 2 P06865 1 +CD36 family [IPR002159] 0.973262032085562 1.7967403559848183 0.0723768490513094 1.0 0.1763759749009311 2 Q14108 1 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9691027926322048 1.780298705071483 0.0750270889479907 1.0 0.1804151255160167 2 Q99595 1 +Tetraspanin/Peripherin [IPR018499] 0.968805704099822 1.779123945205994 0.0752194437526205 1.0 0.1804151255160167 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.968805704099822 1.779123945205994 0.0752194437526205 1.0 0.1804151255160167 2 O60637 1 +Ephrin receptor type-A /type-B [IPR016257] 0.9649435531788472 1.7638479097838546 0.0777575888288795 1.0 0.1841104667313993 2 Q15375 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9800891530460624 1.72900761142083 0.0838077328375528 1.0 0.192623812241196 3 P10619,Q9HB40 2 +Beta tubulin [IPR002453] 0.7906926789702013 1.7089005107054034 0.0874693799111903 1.0 0.1981630742374345 5 P04350,Q9BUF5,P07437 3 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.9489007724301846 1.7003193512248311 0.0890708724447917 1.0 0.2001001891381258 2 Q9UBM7 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9486036838978024 1.6991419005154804 0.0892924502118788 1.0 0.2003299524403177 2 Q5VW38 1 +Nucleobindin [IPR040250] 0.9453357100415928 1.6861878772631231 0.0917596181046631 1.0 0.2034909097299642 2 P80303 1 +Tubulin [IPR000217] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.2087966898041863 6 P04350,Q9BUF5,Q13885,P07437 4 +Desmosomal cadherin [IPR009122] 0.9625557206537892 1.6660804250821544 0.095697396808815 1.0 0.2095303408978116 3 Q14574,Q02487 2 +Major facilitator, sugar transporter-like [IPR005828] 0.9340463458110532 1.64141217368709 0.1007118845460905 1.0 0.2159423009157269 2 Q7L0J3 1 +Basigin-like [IPR043204] 0.9286987522281652 1.6201916481318963 0.1051911149515629 1.0 0.2230107997163981 2 Q6PCB8 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.9402674591381874 1.5859030367374003 0.112761306858639 1.0 0.2328049515488705 3 P39687,Q92688 2 +Chloride channel, voltage gated [IPR001807] 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.2414145062835802 2 P51790 1 +Tropomyosin [IPR000533] 0.8817587641117058 1.4339012552951425 0.1516004436032159 1.0 0.2841053864619596 2 P06753 1 +Constitutive coactivator of PPAR-gamma [IPR026784] 0.871360665478313 1.3927071719522854 0.1637083589505408 1.0 0.2990814358918501 2 Q9NZB2 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.858882947118244 1.3433570586485195 0.1791563844268189 1.0 0.3169218885144275 2 Q96PU5 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8647845468053494 1.3139714016223525 0.188855828416468 1.0 0.3295744328670393 3 P28072,P28074 2 +Presenilin/signal peptide peptidase [IPR006639] 0.8641901931649336 1.3118351861505833 0.1895757500233157 1.0 0.3301948611804596 3 P49768,Q8TCT8 2 +Hypoxanthine phosphoribosyl transferase [IPR005904] 0.8452168746286395 1.289447158839706 0.197242675486966 1.0 0.3387557203816573 2 Q9NRG1 1 +Sulfotransferase [IPR005331] 0.8413547237076692 1.2742444497677192 0.2025767966887661 1.0 0.3462435692735443 2 Q7LGA3 1 +CTP synthase [IPR004468] 0.8330362448009515 1.2415575547866584 0.2143998504598239 1.0 0.3600693140752916 2 Q9NRF8 1 +Septin [IPR016491] 0.670234909307159 1.2350758319515065 0.2168022830643554 1.0 0.362691860743731 5 Q15019,Q16181,Q9NVA2,Q9UHD8 4 +ThiF/MoeB/HesA family [IPR045886] 0.5897519155522836 1.2080102654840548 0.2270433137604857 1.0 0.3721267232502451 9 Q8TBC4,O95396,Q9UBT2,O95352,Q13564 5 +Ancient conserved domain protein family [IPR045095] 0.8119429590017861 1.159096868588288 0.2464167021595433 1.0 0.3941448857780582 2 Q8NE01 1 +Small GTPase, Ras-type [IPR020849] 0.6926064015507638 1.1355589803124186 0.2561411844844057 1.0 0.4032198208306825 4 P11233 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7925107967004749 1.0565128573845577 0.2907339698497897 1.0 0.4355444671232383 3 Q06787 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.7825311942959062 1.0454736748971234 0.2958041012968599 1.0 0.4402190995723252 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.7825311942959062 1.0454736748971234 0.2958041012968599 1.0 0.4402190995723252 2 Q93050 1 +Profilin1/2/3, vertebrate [IPR005454] 0.781639928698755 1.0420612261717273 0.2973832937017713 1.0 0.4414275543415063 2 P07737 1 +Profilin [IPR005455] 0.781639928698755 1.0420612261717273 0.2973832937017713 1.0 0.4414275543415063 2 P07737 1 +Translation initiation factor IF2/IF5 [IPR045196] 0.7789661319073146 1.0318361892084682 0.3021488628855848 1.0 0.4460703121208748 2 P55010 1 +YTH domain containing protein [IPR045168] 0.7786538442920354 1.0079852048698064 0.3134615649831702 1.0 0.4580680576942092 3 Q7Z739 1 +Microtubule associated protein 1 [IPR026074] 0.7607726597325418 0.9459681239830828 0.3441648447886138 1.0 0.4856590067137037 3 Q66K74,P78559 2 +Snf7 family [IPR005024] 0.5709364753108037 0.9426266746617388 0.3458718908874367 1.0 0.4870309838975564 6 Q9H444,Q9Y3E7,Q9UQN3 3 +Microtubule-associated protein RP/EB [IPR027328] 0.7513368983957258 0.9273937795205808 0.3537221191746305 1.0 0.4945612341566416 2 Q15691 1 +Flotillin family [IPR027705] 0.7436125965537771 0.8986484624156184 0.368839936524624 1.0 0.5082842149764254 2 O75955 1 +SCAMP [IPR007273] 0.7337295690936115 0.8537705817881794 0.3932321174789708 1.0 0.5292088498409523 3 O15127,O15126 2 +Syntaxin [IPR045242] 0.5449253836184318 0.8401625073716054 0.4008172768682669 1.0 0.5346710340814838 6 Q86Y82,O15400,Q9UNK0,P56962 4 +S-phase kinase-associated protein 1-like [IPR001232] 0.7245989304812883 0.8288994021353226 0.4071613337223687 1.0 0.5395460991671737 2 P63208 1 +SH3-binding, glutamic acid-rich protein [IPR006993] 0.7204396910279313 0.813852102616158 0.4157296826415666 1.0 0.545510494707882 2 Q9H299 1 +Dynein family light intermediate chain [IPR022780] 0.7192513368984008 0.8095677723911882 0.4181886367689635 1.0 0.5471547987654589 2 O43237 1 +Dynein 1 light intermediate chain [IPR008467] 0.7192513368984008 0.8095677723911882 0.4181886367689635 1.0 0.5471547987654589 2 O43237 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.7180629827688703 0.8052901903300715 0.4206522412481783 1.0 0.5492674068366729 2 O60884 1 +Proteasome alpha-type subunit [IPR023332] 0.5175684615568281 0.7740840800054961 0.4388810712751327 1.0 0.5650866728656934 7 P25788,P60900 2 +Translin family [IPR002848] 0.7055852644087998 0.7608007580851553 0.4467760815532557 1.0 0.5706488144897915 2 Q99598 1 +Ras GTPase-activating protein-binding protein [IPR039539] 0.702614379084973 0.7503279290524021 0.4530572256174126 1.0 0.5767398425469079 2 Q13283 1 +Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349] 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.586007075084875 2 P28482 1 +NudC family [IPR037898] 0.6900445765230323 0.7102312113406162 0.4775607690408949 1.0 0.5971092983070768 3 Q8IVD9,Q9Y266 2 +Developmentally regulated GTP-binding protein [IPR045001] 0.6868686868686931 0.6956596044560157 0.4866420290449387 1.0 0.6031737801019175 2 P55039 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.4776785714285732 0.6666728900959488 0.5049810989779508 1.0 0.6143941693171561 8 P40227,P49368,P50991,P50990,P48643,P17987,Q99832 7 +Gamma-tubulin complex component protein [IPR007259] 0.6752822341057703 0.6564056308470542 0.5115631684108033 1.0 0.6180791222442384 2 Q96CW5 1 +Protein phosphatase 2C family [IPR015655] 0.6687123320905537 0.6432698323506651 0.5200490277241256 1.0 0.6245414773782075 3 Q9H0C8 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6690433749257347 0.6356402072231363 0.525010956668488 1.0 0.627497725091303 2 Q5VTR2 1 +Glycosyl transferase, family 35 [IPR000811] 0.6681521093285869 0.6326958953936118 0.5269322508049219 1.0 0.6284334862134275 2 P06737 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.6681521093285869 0.6326958953936118 0.5269322508049219 1.0 0.6284334862134275 2 P06737 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.6601307189542557 0.6064554345634643 0.5442123671180363 1.0 0.6399007751483317 2 Q96F07 1 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.6446626494280732 3 Q01813,P08237 2 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.6446626494280732 3 Q01813,P08237 2 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.6446626494280732 3 Q01813,P08237 2 +Molecular chaperone regulator BAG [IPR039773] 0.6500253083791232 0.5866875014035715 0.5574136034836015 1.0 0.6486449666436873 3 O95429 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6515151515151592 0.5788099338201175 0.5627174275361944 1.0 0.6517289555025397 2 Q13310 1 +Dynein light chain, type 1/2 [IPR001372] 0.6476530005941847 0.5666064421186956 0.57098159717426 1.0 0.6570139406417354 2 Q96FJ2 1 +DNA mismatch repair MutS family [IPR045076] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.6570882803171793 3 P43246 1 +Calponin/LIMCH1 [IPR001997] 0.6414141414141493 0.5471505292242566 0.5842753202042141 1.0 0.6646613312916511 2 Q15417 1 +26S proteasome regulatory subunit P45-like [IPR005937] 0.4417013682331861 0.4639204316906498 0.6427047538244819 1.0 0.7087004273105068 6 P17980,P62333,P62195,P35998,P62191 5 +DNA-directed DNA polymerase, family B [IPR006172] 0.6056463595839536 0.4616637248527641 0.6443224885061183 1.0 0.709879353024195 3 P28340,P09884 2 +L-lactate dehydrogenase [IPR011304] 0.608734402852059 0.4508866029133952 0.6520712796609458 1.0 0.7147651299290673 2 P00338 1 +Major facilitator superfamily [IPR011701] 0.4517147867895925 0.4361964108423961 0.6626942317902147 1.0 0.7235189182318374 5 Q7L0J3 1 +14-3-3 protein [IPR000308] 0.4191461236081376 0.3924702498270574 0.6947107888963626 1.0 0.7457119542363279 6 P27348,P62258,P63104 3 +Initiation factor 4G [IPR045208] 0.5700997967119481 0.372915804042765 0.7092111091903901 1.0 0.7587591362483379 3 Q04637 1 +Mini-chromosome maintenance protein [IPR031327] 0.4049390062481496 0.3682970072430748 0.7126517838179218 1.0 0.7606884813197712 7 Q9UJA3,P49736,P33991,P33992,P25205,P33993 6 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.5545319465081738 0.3377252484414867 0.7355702460644142 1.0 0.7789099004970148 3 P47897,P07814 2 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.5423476968796449 0.3118635823460321 0.7551442002085837 1.0 0.7986568002206027 3 Q9UBE0,P22314 2 +Protein arginine N-methyltransferase [IPR025799] 0.4341638151497272 0.2977257354334839 0.7659124996434032 1.0 0.8087236022346502 4 O60678 1 +Enolase [IPR000941] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.80911301301189 2 P09104 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.8143618804540216 2 P22314 1 +AP complex subunit beta [IPR026739] 0.5260029717682038 0.2795790358827167 0.7798004928821036 1.0 0.8220463036981198 3 Q10567,O00203 2 +Protein transport protein Sec23 [IPR037364] 0.5338680926916342 0.273011771811604 0.7848441666091031 1.0 0.826017366077413 2 Q15437 1 +Heat shock protein Hsp90 family [IPR001404] 0.4192589875838935 0.2662505574321748 0.7900462485279172 1.0 0.8308166156807191 4 P08238 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.525846702317299 0.2579260119764361 0.7964640092408679 1.0 0.8368854469814723 2 Q10567 1 +Peroxiredoxin, AhpC-type [IPR024706] 0.5169340463458187 0.242109677106346 0.808695179992482 1.0 0.8476723879386566 2 P32119 1 +Importin subunit alpha [IPR024931] 0.3742421704584036 0.2378167231813901 0.8120232475136102 1.0 0.8504719403339632 5 P52292,O60684 2 +UDPGP family [IPR002618] 0.5127748068924667 0.2350698451198012 0.8141545230709568 1.0 0.8520145190892181 2 Q16851 1 +Alpha-D-phosphohexomutase superfamily [IPR005841] 0.5068330362448088 0.2253889677205542 0.8216766933493926 1.0 0.8584978935761922 2 P36871 1 +Macrophage migration inhibitory factor [IPR001398] 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.861978829661083 2 P30046 1 +Arginine-tRNA ligase [IPR001278] 0.4925727866904472 0.2039485388948706 0.8383937135932238 1.0 0.8741994080496628 2 P54136 1 +Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060] 0.4863339275104045 0.1953556468874435 0.8451145362423558 1.0 0.8804977535407476 2 Q8N1G4 1 +Ubiquitin conjugation factor E4 [IPR045132] 0.4842543077837333 0.1925964225278292 0.8472750468845018 1.0 0.8823934894716663 2 O95155 1 +Copper chaperone SCO1/SenC [IPR003782] 0.4806892453951418 0.1879874671414817 0.8508864758024659 1.0 0.8850860929970987 2 O43819 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.4806892453951418 0.1879874671414817 0.8508864758024659 1.0 0.8850860929970987 2 O43819 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.4647218096340544 0.1840866324466735 0.8539454930329624 1.0 0.8871982882253339 3 Q08J23 1 +Dynamin [IPR022812] 0.4627043090638948 0.1816301134158499 0.8558730148240916 1.0 0.8884940192527876 3 O00429,P50570 2 +Ran binding protein RanBP1-like [IPR045255] 0.3652570172819933 0.1760020601171713 0.8602923239733449 1.0 0.8917612044104181 4 Q9H6Z4 1 +H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415] 0.4699940582293648 0.175065552144334 0.8610281256259595 1.0 0.8917612044104181 2 P55769 1 +Vinculin/alpha-catenin [IPR006077] 0.4570579494799421 0.174981727471042 0.8610939914303071 1.0 0.8917612044104181 3 Q9UBT7,P18206 2 +Ribosomal protein L22/L17 [IPR001063] 0.4682115270350634 0.1730417704082018 0.8626185948006082 1.0 0.8929827693375896 2 P18621 1 +Histone deacetylase [IPR003084] 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.8944171895995845 2 Q92769 1 +Histone deacetylase family [IPR000286] 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.8944171895995845 2 Q92769 1 +Cullin [IPR045093] 0.3233194527067131 0.1602680803612778 0.8726699020032556 1.0 0.9007815331047456 6 Q13619,Q93034,Q13620,Q13617,Q13618 5 +Hydantoinase/dihydropyrimidinase [IPR011778] 0.4530600118835558 0.1572890343334612 0.8750170620254456 1.0 0.9022088272995432 2 Q14195 1 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.4350668647845485 0.1521898917617948 0.8790371663014223 1.0 0.9052718608786632 3 Q96P16,Q9NQG5 2 +Ezrin/radixin/moesin [IPR011174] 0.340368608799038 0.1469208794416481 0.8831944713489663 1.0 0.9084687169519574 4 P35241,P26038,P15311 3 +Fructose-bisphosphate aldolase, class-I [IPR000741] 0.4385026737968021 0.1444866494592041 0.885116198020053 1.0 0.9100837189018264 2 P04075 1 +Smooth muscle protein/calponin [IPR003096] 0.4222882615156036 0.1411131599695948 0.8877805475312066 1.0 0.9120984743988736 3 Q99439,Q15417 2 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.4307783719548476 0.1385629269344414 0.8897955406568443 1.0 0.9138058965158384 2 Q6GMV3 1 +E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322] 0.4180035650623953 0.1299945976845423 0.8965707008468462 1.0 0.9196690344001736 2 Q9ULT8 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.4168152109328679 0.129271465895114 0.8971428488767188 1.0 0.919891320480566 2 O75116 1 +Dedicator of cytokinesis [IPR026791] 0.3934621099554254 0.1214303062569022 0.9033502135641804 1.0 0.9258892485956828 3 Q96HP0,Q14185 2 +Serpin family [IPR000215] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.9270287630463688 2 P35237 1 +Aminoacyl-tRNA synthetase, class Ic [IPR002305] 0.3884101040118892 0.118670262673214 0.9055365969788334 1.0 0.9270287630463688 3 P54577,P23381 2 +Chaperone DnaJ [IPR012724] 0.3848439821693926 0.1168352635780069 0.9069905988133578 1.0 0.927648243855761 3 O60884,P31689 2 +Peptidase M3A/M3B [IPR045090] 0.3835405607750695 0.1161873577420897 0.9075040559526996 1.0 0.927648243855761 3 Q9BYT8 1 +Ribosomal protein S2 [IPR001865] 0.3903743315508098 0.1160972297239747 0.9075754843287428 1.0 0.927648243855761 2 P08865 1 +Tyrosine-tRNA ligase [IPR002307] 0.38829471182413 0.1152769849790838 0.908225580060322 1.0 0.9277869583602588 2 P54577 1 +U3 snoRNP protein/Ribosome production factor 1 [IPR044281] 0.3719548425430918 0.1097680125083452 0.9125933600294572 1.0 0.9313058421751718 2 Q9H9Y2 1 +Ribosomal protein L11/L12 [IPR000911] 0.3657159833630494 0.1080621065170561 0.9139464267015992 1.0 0.9323190194338744 2 P30050 1 +TAF15/EWS/TLS family [IPR034870] 0.3610698365527509 0.1067926653578619 0.9149534663954229 1.0 0.9329785543858764 3 Q01844,Q92804 2 +DNA ligase, ATP-dependent [IPR000977] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9334457105176528 2 P18858 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.2800237812128371 0.1047435322358823 0.9165793181992016 1.0 0.9334457105176528 4 Q96BP3,Q13356,Q9Y3C6 3 +GDP-fucose protein O-fucosyltransferase [IPR019378] 0.3475935828877096 0.1041509243527397 0.917049578775544 1.0 0.9334457105176528 2 Q9Y2G5 1 +Ribosomal protein S5/S7 [IPR000235] 0.346405228758178 0.1039424636939488 0.9172150084414183 1.0 0.9334457105176528 2 P46782 1 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.3494799405646381 0.1031205180277729 0.9178673208021207 1.0 0.9335616487805436 3 Q9NQ88,P18669 2 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.32412358882948 0.1009136852659135 0.9196189792964826 1.0 0.9335616487805436 2 P49588 1 +Alanine-tRNA ligase, class IIc [IPR002318] 0.32412358882948 0.1009136852659135 0.9196189792964826 1.0 0.9335616487805436 2 P49588 1 +26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585] 0.3226381461675669 0.1007632364478062 0.9197384113232836 1.0 0.9335616487805436 2 Q15008 1 +Protein PRRC2 [IPR033184] 0.3399702823179812 0.10061760577879 0.9198540202435804 1.0 0.9335616487805436 3 Q9Y520,Q5JSZ5 2 +Prefoldin alpha-like [IPR004127] 0.3325408618127807 0.098947538366071 0.9211799239160992 1.0 0.933698833818724 3 Q99471,P61758 2 +Sorting nexin-5/6/32 [IPR014637] 0.2935234699940683 0.0987448492334923 0.9213408583114004 1.0 0.933698833818724 2 Q9UNH7 1 +Ribosomal protein S14 [IPR001209] 0.2908496732026244 0.0986296704346281 0.9214323112724194 1.0 0.933698833818724 2 P62273 1 +G-protein alpha subunit, group I [IPR001408] 0.2407847800237734 0.0931910721684538 0.9257517669018308 1.0 0.93697519465856 4 P04899,P08754,P63096 3 +La domain containing protein [IPR045180] 0.2543478846414809 0.090263456077244 0.9280778593965062 1.0 0.938618502204661 5 P05455,Q6PKG0,Q92615 3 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..484130052879678b961262c622f0fa909ef800f1 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AF4/FMR2 family [IPR007797]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Abr/Bcr [IPR037769]", "Acetoacetyl-CoA synthase [IPR005914]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2 [IPR033093]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 13 [IPR040182]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 3 [IPR037355]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline transporter-like [IPR007603]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coiled-coil domain-containing protein R3HC1/R3HCL [IPR039884]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta subunit 3 [IPR019038]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad4 [IPR004583]", "DNA repair protein Rad4, subgroup [IPR018026]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Disks large 1-like [IPR016313]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Embigin [IPR027114]", "Emerin [IPR035004]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GPCR, family 2, ADGRE2/ADGRE5 [IPR003056]", "GPCR, family 2, secretin-like [IPR000832]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galanin precursor [IPR008175]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 4 [IPR000715]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Lethal(3)malignant brain tumour-like protein 2 [IPR038038]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MORF4 family-associated protein 1 [IPR029254]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 [IPR030035]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myocardin-like [IPR043451]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NURS complex subunit red1 [IPR039278]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Neogenin [IPR033024]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear pore protein POM121 [IPR026090]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "OPI10 family [IPR031318]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22A, presenilin 1 [IPR002031]", "Peptidase A22A, presenilin [IPR001108]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-B-cell leukemia transcription factor-interacting protein 1 [IPR033589]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein TESPA1-like [IPR043444]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein ITPRID2 [IPR026648]", "Protein LCHN/Anr2 [IPR018626]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein Nucling [IPR030227]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PCF11-like [IPR045154]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1356, TMEM106 [IPR009790]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3512 [IPR021900]", "Protein of unknown function DUF4602 [IPR027973]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase Rpc34 [IPR007832]", "RNA polymerase Rpc34-like [IPR016049]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding region-containing protein RBM41/RNPC3 [IPR045164]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Refilin family [IPR028215]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Roundabout homologue 1 [IPR032986]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatD family [IPR001130]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor NFYB/HAP3 [IPR027113]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 131-like [IPR039877]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase [IPR033895]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterized protein C11orf98 [IPR037691]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 89 [IPR039328]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "ZZ-type zinc finger-containing protein 3 [IPR037830]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA splicing factor Cwf18-like [IPR013169]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [IPR004416]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related [IPR002218]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFF4", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANKLE2", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAX", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C11orf98", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf131", "C1orf35", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CDS2", "CDV3", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG5", "COG7", "COIL", "COLGALT1", "COMMD3", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1B", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", 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"GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP2", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS13", "INTS14", "INTS2", "INTS3", "INTS5", "INTS7", "INTS9", "IPO4", "IPO5", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL14", "METTL16", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS3", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRFAP1", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA25", "NAA40", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NEO1", "NES", "NF2", "NFS1", "NFYB", "NGDN", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRDE2", "NRM", "NRP1", "NSA2", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCIAD2", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKP2", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "REXO4", "RFC1", "RFLNB", "RFT1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLK", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG8", "SMIM4", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPNS1", "SPOUT1", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TATDN1", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEFM", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TLE3", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM131", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBR4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGGT2", "UGP2", "UHRF1", "UMPS", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS26B", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VTA1", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR11", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR46", "WDR82", "WDR89", "WFS1", "WIPI2", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H4", "ZC3H7A", "ZCCHC3", "ZFC3H1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZZZ3"], "leading_proteins": ["AARS", "ALDOA", "ANP32A", "ANP32B", "AP1B1", "AP3B1", "APLP2", "ATG7", "ATP6V0A1", "BAG4", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CHMP2B", "CHMP3", "CHMP4B", "CLCN3", "CNN2", "CNN3", "CNNM3", "CTNNAL1", "CTPS2", "CTSA", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYFIP2", "DDT", "DHCR7", "DNAJA1", "DNAJA2", "DNM1L", "DNM2", "DOCK1", "DOCK6", "DPYSL3", "DRG2", "DSC2", "DSC3", "DYNC1LI2", "DYNLL2", "EIF4G1", "EIF5", "EMB", "ENO2", "EPHA7", "EPRS", "EWSR1", "EZR", "FAM120A", "FLOT1", "FMR1", "FUCA2", "G3BP1", "GLB1", "GNAI1", "GNAI2", "GNAI3", "GPR107", "HDAC2", "HECTD1", "HEXA", "HS2ST1", "HSP90AB1", "ILKAP", "KPNA2", "KPNA6", "LAMP2", "LARP1", "LARP4B", "LDHA", "LIG1", "LNPEP", "LRRC47", "MAP1A", "MAP1S", "MAPK1", "MAPRE1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM7", "MCM8", "MOCS3", "MSH2", "MSN", "NAE1", "NAP1L1", "NAP1L4", "NEDD4L", "NLN", "NPEPPS", "NSUN2", "NUCB2", "NUDC", "NUDCD3", "PABPC4", "PFDN5", "PFKM", "PFKP", "PFN1", "PGAM1", "PGM1", "POFUT2", "POLA1", "POLD1", "PPIL1", "PPIL2", "PPT2", "PPWD1", "PRDX2", "PRMT3", "PRRC2B", "PRRC2C", "PRTFDC1", "PSEN1", "PSMA3", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC5", "PSMC6", "PSMD6", "PTRHD1", "PYGL", "QARS", "RALA", "RANBP3", "RARS", "RDX", "RNF20", "ROCK2", "RPF1", "RPL12", "RPL17", "RPRD1A", "RPRD1B", "RPS29", "RPS5", "RPSA", "SAE1", "SCAMP1", "SCAMP2", "SCARB2", "SCO2", "SCPEP1", "SEC23B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SET", "SH3BGRL3", "SKP1", "SNU13", "SNX6", "SPPL2A", "SSB", "STX12", "STX17", "STX7", "STX8", "SV2A", "TAF15", "TCP1", "TIGAR", "TIMM17A", "TPM3", "TSNAX", "TSPAN3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP3", "UBA1", "UBA2", "UBA3", "UBE4B", "UGP2", "VBP1", "VCL", "WARS", "YARS", "YTHDF3", "YWHAE", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0d534c78c25a720a138434fec6bfeaa25157adc5 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Immunoglobulin-like fold [IPR013783]", "1": "Immunoglobulin-like domain superfamily [IPR036179]", "2": "Glycoside hydrolase superfamily [IPR017853]", "3": "Glycosyl hydrolase, all-beta [IPR013780]", "4": "Galactose-binding-like domain superfamily [IPR008979]", "5": "Fibronectin type III superfamily [IPR036116]", "6": "Cadherin-like superfamily [IPR015919]", "7": "Leucine-rich repeat domain superfamily [IPR032675]", "8": "Nucleophile aminohydrolases, N-terminal [IPR029055]", "9": "Alpha/Beta hydrolase fold [IPR029058]"} \ No newline 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sha256:619e626c393786cbeb05e23317a8a0b4d93fdb183ec72299961fb89c9fb895aa +size 137947 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..85758cad0e5c5860f458cf384ae810ac6b2144d8 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4fec6e315a8822a38ca40cc2c65af4067b3274addf93afa9d63a82fdd34f4588 +size 174368 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c5148bd089259cad7cc9d197792b140cf52c2725 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,17 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Immunoglobulin-like fold [IPR013783] 21 43 3.836421178571222 0.000124840238258 9.024271844660197 30.70631067961165 -0.0882371106398617 0.5574652875269992 4.075666983819175 5.992200349595445 1.1066442573771362 0.3307702752839019 0.1108875195700984 0.0977685574948473 0.0065495537048662 5.84502190709701e-07 0.0002510331562824 +Immunoglobulin-like domain superfamily [IPR036179] 16 20 3.2700118768847743 0.0010754296892216 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.2405158148653939 0.1090224971962506 0.0053807722164466 1.7155774979918688e-08 1.0344173618197924e-05 +Glycoside hydrolase superfamily [IPR017853] 10 15 3.126179271662419 0.0017709355916013 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 1.8953118692755423e-11 1.4061110647098428e-07 1.584453152491889e-12 8.269381770587993e-12 1.3128912873403104e-08 +Glycosyl hydrolase, all-beta [IPR013780] 6 9 2.6547744625437804 0.0079361449619566 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 3.9720496110652437e-10 3.066034551708988e-05 1.2418754455482902e-09 7.213715336739811e-09 8.329520797212374e-07 +Galactose-binding-like domain superfamily [IPR008979] 5 12 2.477754101705812 0.013221222855724 3.0266990291262137 10.45388349514563 0.2272915730277323 0.4946686484554474 2.0113188873716883 2.8129916124420524 1.0072294248002038 0.3052099564304033 0.0081785542562459 1.0 0.0135653143077038 0.0014327621348651 0.0030132274761459 +Immunoglobulin E-set [IPR014756] 3 17 2.4759107205977924 0.0132896806012261 3.4563106796116503 15.148058252427184 0.2670321239563391 0.4966749963270377 2.426698980572813 2.6319399461427304 0.9943374164221532 0.3081935983105719 0.0760409900665791 0.2412174988663298 0.0174347284732116 0.0474607851235824 0.1361256245763561 +Fibronectin type III superfamily [IPR036116] 5 10 2.4024522894806672 0.0162855588023342 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.4414139941253555 0.295480255529908 0.5045129832066302 0.0076080813078773 0.131474990685951 +Cadherin-like superfamily [IPR015919] 6 7 2.3943153543802045 0.0166514251672813 1.645631067961165 3.320388349514563 -0.2402178645885725 0.4384898024191497 1.130192585962622 1.2673157339720058 1.2853782186760632 0.3326205753213853 0.0007164091674755 0.0051137089586154 0.001231210484404 1.0729957836567851e-05 5.636361715141554e-05 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 4 6 2.393506357424339 0.0166881921170518 1.2203856749311297 2.6942148760330578 -0.1665405502801967 0.33863481843602 1.1834128472166114 1.8370669604533123 1.6157864534436548 0.3193113842408702 0.0086290067493602 0.0267403422938185 0.0142951840993497 0.0085171031160944 0.0397377338982377 +Leucine-rich repeat domain superfamily [IPR032675] 7 29 2.2648988403971404 0.0235188879591168 9.485436893203884 27.478155339805824 -0.5625312407848868 0.5346940610561808 4.410081296544774 4.878326198619911 0.8243099870624175 0.3136560552437855 0.2405158148653939 1.0 0.3116411944565507 0.0070810875015532 0.1082520912916579 +Nucleophile aminohydrolases, N-terminal [IPR029055] 8 19 2.2597080929310343 0.023839373694849 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 1.0 1.0 0.2186221342412543 0.002932051876052 1.5611785984141917e-05 +Galactose mutarotase-like domain superfamily [IPR011013] 2 6 2.238846741028 0.0251658898298445 1.6213592233009708 4.237864077669903 -0.1710088816529627 0.4259251030719748 1.156379559873228 0.9330622415325056 1.182861393037172 0.315870474383572 2.828730351654048e-05 1.0 4.947049331965399e-05 0.0007358710981923 0.0053637976870067 +Alpha/Beta hydrolase fold [IPR029058] 10 26 2.168209931648243 0.0301427175103663 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 6.045222714223109e-08 8.116996873619197e-07 1.5572107015682725e-08 5.673699596492944e-07 1.6916505951245532e-05 +Six-bladed beta-propeller, TolB-like [IPR011042] 2 7 2.1539099283086323 0.0312472362149249 1.3446601941747574 5.393203883495145 0.4812306698455429 0.3983263887517446 1.462357994456035 1.8263849452238317 1.127948748997717 0.299664609287172 0.0160900301160464 0.0060718409625537 0.0228441699597423 0.0199432580741765 0.0272826327042602 +Peptidase M4/M1, CTD superfamily [IPR027268] 2 6 1.973040745678617 0.0484909202988617 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0709501192712976 0.0432957136582515 0.0849171013653387 0.0190953097419897 0.0077568745967145 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 2 6 1.973040745678617 0.0484909202988617 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0709501192712976 0.0432957136582515 0.0849171013653387 0.0190953097419897 0.0077568745967145 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2051b30802feea71f57c3da54bff0edf5be15dfb --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 1001, + "title": "Average number of proteins per term", + "value": 4.98001998001998 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cdb7360291ba8055b54a68953a4b77bf0bf83d60 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ff01c349ca6899184726c0a34cc24107328c71dc --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,185 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Immunoglobulin-like fold [IPR013783] 0.8191200545445267 3.836421178571222 0.000124840238258 0.1174791633165734 0.1059125897879608 43 P55899,P13591,Q6PCB8,O94898,Q92859,Q9Y6N7,P78310,Q8IZA0,Q13740,Q6YHK3,P10586,P04439,Q08722,P43121,P01889,Q9Y624,Q92692,P35613,Q15375,P29317,P10321 21 +Immunoglobulin-like domain superfamily [IPR036179] 0.9000161590835004 3.2700118768847743 0.0010754296892216 0.6594129004185108 0.1059125897879608 20 P55899,P04439,P01889,P13591,Q6PCB8,O94898,P10586,Q9Y624,Q92859,Q92692,P35613,Q9Y6N7,Q13740,P78310,P10321,P43121 16 +Glycoside hydrolase superfamily [IPR017853] 0.9290865205370318 3.126179271662419 0.0017709355916013 0.8303941489992295 0.1059125897879608 15 P04066,P04062,P54802,Q8IW92,P06280,P10253,Q9BTY2,P07686,P16278,P06865 10 +Glycosyl hydrolase, all-beta [IPR013780] 0.9352143658260912 2.6547744625437804 0.0079361449619566 0.9996563103797752 0.1059125897879608 9 P04066,P06280,P10253,Q9BTY2,O00754,Q9Y2E5 6 +Galactose-binding-like domain superfamily [IPR008979] 0.8250423804130218 2.477754101705812 0.013221222855724 0.9999983631071294 0.1203358928678241 12 Q08431,Q8IW92,Q15375,P16278,P29317 5 +Immunoglobulin E-set [IPR014756] 0.7633602502834528 2.4759107205977924 0.0132896806012261 0.999998472926586 0.1203358928678241 17 Q6YHK3,O43924,P61916 3 +Fibronectin type III superfamily [IPR036116] 0.8469650202433147 2.4024522894806672 0.0162855588023342 0.9999999272360872 0.1325784151521342 10 P13591,Q92859,Q15375,P29317,Q9Y6N7 5 +Cadherin-like superfamily [IPR015919] 0.9211544183278698 2.3943153543802045 0.0166514251672813 0.9999999498581688 0.1325784151521342 7 Q14126,P19022,Q02487,O60245,Q14517,Q14574 6 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.9396020044438363 2.393506357424339 0.0166881921170518 0.9999999517001728 0.1325784151521342 6 P01130,Q15375,P48960,Q07954 4 +Leucine-rich repeat domain superfamily [IPR032675] 0.6418165076729765 2.2648988403971404 0.0235188879591168 0.999999999954969 0.1471400427942246 29 O94898,Q13309,P39687,Q13641,O94813,Q92688,Q9Y2I1 7 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.699815869843696 2.2597080929310343 0.023839373694849 0.9999999999675804 0.1473391381070703 19 Q99436,P28074,P28070,P25788,P28072,Q9UJ14,P60900,P49721 8 +Galactose mutarotase-like domain superfamily [IPR011013] 0.8982161243373774 2.238846741028 0.0251658898298445 0.9999999999916892 0.1508365148778753 6 P10253,O00754 2 +LDL receptor-like superfamily [IPR036055] 0.986645789343353 2.2365583556630715 0.0253152192802028 0.9999999999928708 0.1508365148778753 4 P01130,Q9NPF0 2 +Alpha/Beta hydrolase fold [IPR029058] 0.6425125619220133 2.168209931648243 0.0301427175103663 0.9999999999999504 0.1665318996132658 26 P34913,P42785,Q9H3G5,Q9HB40,Q8NCC3,Q9UMR5,P10619,P50897,P38571,Q4J6C6 10 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.9640309155766932 2.15466065273199 0.0311883989851171 0.9999999999999832 0.1690728835196751 4 P55899,P01889,P04439 3 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.9640309155766932 2.15466065273199 0.0311883989851171 0.9999999999999832 0.1690728835196751 4 P55899,P01889,P04439 3 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.8582357902794773 2.1539099283086323 0.0312472362149249 0.9999999999999842 0.1690728835196751 7 P01130,Q07954 2 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.9455147657941844 2.0871268177158755 0.036876672485274 1.0 0.185495221898288 4 P20645,P11717 2 +Catenin binding domain superfamily [IPR027397] 0.94322235434007 2.078736319181473 0.037641592826239 1.0 0.1883961720953263 4 Q14126,Q14574,Q02487 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8287233876662697 1.973040745678617 0.0484909202988617 1.0 0.2147761558369936 6 P55786,Q9UIQ6 2 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8287233876662697 1.973040745678617 0.0484909202988617 1.0 0.2147761558369936 6 P55786,Q9UIQ6 2 +NAP-like superfamily [IPR037231] 0.9114149821640884 1.9616706453575312 0.049800841553117 1.0 0.2167419234550876 4 Q99733,Q01105,P55209 3 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.6314787749094317 1.9465123059643223 0.0515932311837095 1.0 0.2216516069308721 21 O94813,Q12899,O14786,Q14517 4 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.2466111287775388 2 Q06481 1 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.2466111287775388 2 Q06481 1 +E2 domain superfamily [IPR036176] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.2466111287775388 2 Q06481 1 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9943553178847296 1.879963867978085 0.0601130024193001 1.0 0.2466111287775388 2 Q06481 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.9919786096256684 1.870600988739804 0.0614004074662644 1.0 0.2478298704585914 2 Q5KU26 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.968805704099822 1.779123945205994 0.0752194437526205 1.0 0.2765114316803866 2 O60637 1 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.96850861556744 1.7779491388722284 0.0754122086401054 1.0 0.2765114316803866 2 O75976 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.964646464646465 1.7626725172782438 0.0779557385469007 1.0 0.276991315137216 2 O43924 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.7587985867834984 1.7607049776594703 0.0782883498272595 1.0 0.276991315137216 7 P04350,Q9BUF5,P07437,Q13885,Q9BUK6 5 +Spermadhesin, CUB domain superfamily [IPR035914] 0.9625668449197876 1.7544435576127702 0.0793545332856455 1.0 0.2777408664997595 2 Q6UXD5 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.975631500742942 1.7130235511499157 0.0867082069457705 1.0 0.2977255119020003 3 P54802,P06865 2 +Fibronectin type II domain superfamily [IPR036943] 0.9754182757639832 1.7122587195952068 0.0868490004749091 1.0 0.2977255119020003 3 P11717 1 +Kringle-like fold [IPR013806] 0.9754182757639832 1.7122587195952068 0.0868490004749091 1.0 0.2977255119020003 3 P11717 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.3150153831360237 6 P04350,Q9BUF5,Q13885,P07437 4 +Tubulin, C-terminal [IPR023123] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.3150153831360237 6 P04350,Q9BUF5,Q13885,P07437 4 +Tubulin/FtsZ, C-terminal [IPR008280] 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.3150153831360237 6 P04350,Q9BUF5,Q13885,P07437 4 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.7772388978614293 1.6564412295617714 0.0976324974670399 1.0 0.3152565002068662 5 P42892 1 +Ricin B-like lectins [IPR035992] 0.9493807382855358 1.61870704889198 0.105510309517963 1.0 0.3300494369608781 3 Q9UBG0 1 +C-type lectin fold [IPR016187] 0.9417838946375916 1.591363286001732 0.1115278418104885 1.0 0.3378219264414059 3 Q5KU26 1 +PIN-like domain superfamily [IPR029060] 0.7534593208001243 1.5633152726729018 0.1179784577545979 1.0 0.3391763411969968 5 Q9UQ84,Q9NZB2 2 +Chloride channel, core [IPR014743] 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.3391763411969968 2 P51790 1 +Integrin domain superfamily [IPR032695] 0.9201448106733122 1.513399229391334 0.1301782806347704 1.0 0.3599681185508431 3 P06756 1 +Class I glutamine amidotransferase-like [IPR029062] 0.6722559655937002 1.486870268655923 0.137049078068157 1.0 0.3748254840060797 8 Q92820,Q9NRF8 2 +Cyclic nucleotide-binding-like [IPR018490] 0.7323219768378323 1.4801803391524362 0.1388251258697379 1.0 0.3755782459340748 5 Q6P4Q7,Q9Y4G8,P10644 3 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3824068937306789 3 O00754 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3824068937306789 3 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3824068937306789 3 O00754 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.90444725554212 1.456807771140156 0.1451694501674905 1.0 0.3824068937306789 3 O00754 1 +PX domain superfamily [IPR036871] 0.5872170436104965 1.3848335539284429 0.1661033683751847 1.0 0.4132253072589012 12 Q9UMY4,Q13596,O95219,O60749,Q96L92,O60493,Q9Y2I1 7 +BSD domain superfamily [IPR035925] 0.8392751039809869 1.2660651179856923 0.2054897697421724 1.0 0.4808467014987191 2 P32780 1 +Ubiquitin-activating enzyme [IPR035985] 0.5897519155522836 1.2080102654840548 0.2270433137604857 1.0 0.5017794808937128 9 Q8TBC4,O95396,Q9UBT2,O95352,Q13564 5 +EF-hand domain pair [IPR011992] 0.42799653879252 1.1833021200484473 0.2366894328985744 1.0 0.5128271046135779 55 P80303,O75071,O43852,Q9H8M7,Q0IIM8,O95302,Q14257,Q7L5N7,P41208,Q02818,P42566,Q9H223,Q9H4M9 13 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.8149138443256119 1.1706689908640917 0.2417318541528428 1.0 0.5135839620439179 2 P24534 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.8149138443256119 1.1706689908640917 0.2417318541528428 1.0 0.5135839620439179 2 P24534 1 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.5237746336920232 1.1165760151110111 0.2641756515909643 1.0 0.5377789737487806 13 Q9Y3Z3,Q15375,P29317 3 +SNARE [IPR010989] 0.6046228538499379 1.0774101642498817 0.2812970652362261 1.0 0.5586872267886157 6 Q86Y82,O15400,P56962,Q9UEU0 4 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.5254357295372064 1.0491374084477016 0.29411488114139 1.0 0.5747146006727522 11 Q16763,Q9Y3C8,Q9C0C9,P61088,Q99816,P49459 6 +Profilin superfamily [IPR036140] 0.781639928698755 1.0420612261717273 0.2973832937017713 1.0 0.5791452859834106 2 P07737 1 +Translation initiation factor IF2/IF5, N-terminal [IPR016189] 0.7789661319073146 1.0318361892084682 0.3021488628855848 1.0 0.5861453716055629 2 P55010 1 +Translation initiation factor IF2/IF5, zinc-binding [IPR016190] 0.7789661319073146 1.0318361892084682 0.3021488628855848 1.0 0.5861453716055629 2 P55010 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.7614379084967354 0.965300715614032 0.3343942134786264 1.0 0.6220584221481607 2 Q9BYT8 1 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.530770422025719 0.9476835419681328 0.343290581908465 1.0 0.6273053087239026 9 Q0IIM8,O60343,Q9BXI6,Q8TC07,Q4KMP7 5 +BRO1 domain superfamily [IPR038499] 0.7566844919786133 0.9474193516688588 0.3434251340036613 1.0 0.6273053087239026 2 Q5VW32 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.7549019607843175 0.9407332215465808 0.3468415897324204 1.0 0.6301060459567202 2 Q8TBC4 1 +EB1, C-terminal domain superfamily [IPR036133] 0.7513368983957258 0.9273937795205808 0.3537221191746305 1.0 0.6379744888176668 2 Q15691 1 +PH-like domain superfamily [IPR011993] 0.3952562067555791 0.9191059652702976 0.3580401494125733 1.0 0.6424657496411745 59 Q06481 1 +Phosphoribosyltransferase-like [IPR029057] 0.5382090993161324 0.9157347091758924 0.3598060555271689 1.0 0.6424657496411745 8 Q9NRG1,Q14558,P00492,P07741 4 +NET domain superfamily [IPR038336] 0.7451319399807046 0.8923831137931704 0.3721876189492819 1.0 0.6424657496411745 3 Q15059 1 +CAP Gly-rich domain superfamily [IPR036859] 0.7446946597910712 0.8908949322499655 0.3729855392889947 1.0 0.6426136399798342 3 Q99426 1 +Gamma-glutamyl cyclotransferase-like superfamily [IPR036568] 0.7323232323232367 0.8570514790127471 0.3914164349598337 1.0 0.6519265414222855 2 Q8WUX2 1 +Nucleoside phosphorylase superfamily [IPR035994] 0.7254901960784361 0.8321341851742442 0.4053332079046619 1.0 0.666036368759851 2 P00491 1 +MFS transporter superfamily [IPR036259] 0.4958382899867413 0.7959813750582585 0.4260428609609215 1.0 0.6834437561248116 9 Q7L0J3,Q9H2V7,O00400 3 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.5207131330141666 0.7865268625613832 0.4315588879614431 1.0 0.6902489385636082 7 Q10713 1 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.4479970194629466 0.7863470906748438 0.4316641713694493 1.0 0.6902489385636082 15 Q9UJU6,O95487,Q15437,Q6IBS0,P23528,P60983 6 +eRF1, domain 2 superfamily [IPR042226] 0.7121212121212176 0.7840059558689889 0.4330366155792911 1.0 0.6913391582055349 2 Q9BRX2 1 +DUSP-like superfamily [IPR035927] 0.7058222569928634 0.7611752459326236 0.4465524015155293 1.0 0.6998792764238012 3 Q8TEY7 1 +Translin, C-terminal [IPR016069] 0.7055852644087998 0.7608007580851553 0.4467760815532557 1.0 0.6998792764238012 2 Q99598 1 +Translin superfamily [IPR036081] 0.7055852644087998 0.7608007580851553 0.4467760815532557 1.0 0.6998792764238012 2 Q99598 1 +Translin, N-terminal [IPR016068] 0.7055852644087998 0.7608007580851553 0.4467760815532557 1.0 0.6998792764238012 2 Q99598 1 +HIT-like superfamily [IPR036265] 0.7046062407132253 0.7572098477278916 0.4489241512995088 1.0 0.702145430391888 3 Q69YN2,Q96C86 2 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.7001549786662231 0.7427485176481305 0.457633949687962 1.0 0.7085833601142184 3 P47756 1 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.7001549786662231 0.7427485176481305 0.457633949687962 1.0 0.7085833601142184 3 P47756 1 +Protein-tyrosine phosphatase-like [IPR029021] 0.4529251968091554 0.7118666113997455 0.4765473794181385 1.0 0.7190042573231558 11 P10586,O14976,Q9ULE6,P51452,Q8NCE2,Q99956 6 +Rho GTPase activation protein [IPR008936] 0.4350724823721821 0.6786852513770775 0.4973373130876883 1.0 0.7331879976447364 13 Q07960,Q9UIW2,Q86VI3,Q9H0H5,O00459 5 +Signal recognition particle, SRP9/SRP14 subunit [IPR009018] 0.6797385620915097 0.6713999377092076 0.5019657846005021 1.0 0.7362172286888781 2 P37108 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.6752822341057703 0.6564056308470542 0.5115631684108033 1.0 0.7436352626258474 2 Q96CW5 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.6687123320905537 0.6432698323506651 0.5200490277241256 1.0 0.7499737517380193 3 Q9H0C8 1 +HR1 repeat superfamily [IPR036274] 0.670528817587648 0.6405598507612354 0.5218086918914795 1.0 0.7504748571600157 2 Q16512 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.5080299695539584 0.619809447188522 0.5353832482066667 1.0 0.7645058936588778 5 Q9UMX5 1 +Phosphofructokinase superfamily [IPR035966] 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.7733449382088313 3 Q01813,P08237 2 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.4473343184856649 0.5930288962726052 0.5531618139435797 1.0 0.7733449382088313 9 P08183,P33527 2 +BAG domain superfamily [IPR036533] 0.6500253083791232 0.5866875014035715 0.5574136034836015 1.0 0.7760375759208415 3 O95429 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.5341854934601552 0.5715912802960401 0.5675989041960636 1.0 0.7825662449444226 4 P53992,O95487,Q15437 3 +I/LWEQ domain superfamily [IPR035964] 0.6485442661913328 0.569411974412891 0.5690765924623049 1.0 0.7825662449444226 2 Q9Y490 1 +Dynein light chain superfamily [IPR037177] 0.6476530005941847 0.5666064421186956 0.57098159717426 1.0 0.7825662449444226 2 Q96FJ2 1 +MutS, connector domain superfamily [IPR036678] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7825662449444226 3 P43246 1 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7825662449444226 3 P43246 1 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.7825662449444226 3 P43246 1 +High mobility group box domain superfamily [IPR036910] 0.4141115960679515 0.5583156539939277 0.5766288573791356 1.0 0.7863834962350337 12 O15347,P09429,O96028,P26583,O94842 5 +ArfGAP domain superfamily [IPR038508] 0.6335809806835078 0.5387157279212308 0.5900830196345177 1.0 0.7939154605566562 3 Q8N6T3,Q8IYB5 2 +ARFGAP/RecO-like zinc finger [IPR037278] 0.6335809806835078 0.5387157279212308 0.5900830196345177 1.0 0.7939154605566562 3 Q8N6T3,Q8IYB5 2 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.5090647247596838 0.4939458359476192 0.6213444324655908 1.0 0.8194542515125908 4 O95831 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.4117242805804325 0.489561728598693 0.6244440638149236 1.0 0.8194670429708291 10 Q96PU5,Q96J02,P46934 3 +DNA polymerase family B, thumb domain [IPR042087] 0.6056463595839536 0.4616637248527641 0.6443224885061183 1.0 0.8311427976734851 3 P28340,P09884 2 +DNA polymerase, palm domain superfamily [IPR023211] 0.6056463595839536 0.4616637248527641 0.6443224885061183 1.0 0.8311427976734851 3 P28340,P09884 2 +TFIIS/LEDGF domain superfamily [IPR035441] 0.4217944603548498 0.4222554312645893 0.6728385855365693 1.0 0.8532960945674123 7 Q96ST2 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.3649889666147593 0.40847260208742 0.6829267411024893 1.0 0.8609693549667403 20 O43772,Q9BSK2 2 +SH3-like domain superfamily [IPR036028] 0.3510984861029705 0.400462859035323 0.6888156340248721 1.0 0.8666270304618874 35 Q9UKS6,Q14247,Q14847,Q9UJU6,Q9UQB8,P62993,P46108,Q9UNF0,O00459,Q14168 10 +14-3-3 domain superfamily [IPR036815] 0.4191461236081376 0.3924702498270574 0.6947107888963626 1.0 0.8692568746065737 6 P27348,P62258,P63104 3 +PABC (PABP) domain [IPR036053] 0.5667391408502666 0.3651203398995752 0.7150215784537803 1.0 0.8803648216878648 3 Q13310 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.4571938168846514 0.3516331422950673 0.7251134066521889 1.0 0.8851689269010258 4 Q9UBT7,P18206,Q9Y490 3 +Rhodanese-like domain superfamily [IPR036873] 0.4552234057194527 0.3467799597468658 0.7287566337829381 1.0 0.8885327532481377 4 Q99956 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.5623885918003664 0.3330871576294195 0.739068493148757 1.0 0.8967364383538252 2 P07814 1 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.5623885918003664 0.3330871576294195 0.739068493148757 1.0 0.8967364383538252 2 P07814 1 +Cyclin-like superfamily [IPR036915] 0.5405646359583969 0.3082061343805286 0.7579254849659265 1.0 0.9112370439858752 3 P14635,P06400 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.3433885455220936 0.2971393798604447 0.7663601005297309 1.0 0.9113545493236916 20 Q8NB78,Q96CU9,P22570,Q16881,Q9UHG3,O95831 6 +Enolase-like, C-terminal domain superfamily [IPR036849] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.9113545493236916 2 P09104 1 +Enolase-like, N-terminal [IPR029017] 0.5457516339869397 0.2968330960802122 0.7665939365939545 1.0 0.9113545493236916 2 P09104 1 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.9118242120727597 2 P22314 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.9118242120727597 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.542186571598348 0.2895032258271391 0.7721963116824455 1.0 0.9118242120727597 2 P22314 1 +Prefoldin [IPR009053] 0.4230221046222004 0.2739361204947065 0.7841337127685108 1.0 0.9245204316622844 4 Q99471 1 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.5306001188354252 0.2667686053605342 0.7896473277992033 1.0 0.9282116135873768 2 Q9HC38 1 +HSP90, C-terminal domain [IPR037196] 0.4192589875838935 0.2662505574321748 0.7900462485279172 1.0 0.9282116135873768 4 P08238 1 +HSP40/DnaJ peptide-binding [IPR008971] 0.3850728516205828 0.2609168781899555 0.7941566086499694 1.0 0.9319469698225314 5 P25685,Q9UBS4,O60884,P31689 4 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.525846702317299 0.2579260119764361 0.7964640092408679 1.0 0.9335602731265912 2 Q10567 1 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.5069836552748901 0.2455889938735746 0.8060004099668792 1.0 0.9382061011717522 3 P36871,O95394 2 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.5069836552748901 0.2455889938735746 0.8060004099668792 1.0 0.9382061011717522 3 P36871,O95394 2 +RmlC-like jelly roll fold [IPR014710] 0.3502483534313694 0.2455233950377335 0.806051195811895 1.0 0.9382061011717522 9 Q9Y4G8 1 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.342040295280085 0.2395472348251265 0.8106812742725613 1.0 0.9396939546371372 10 Q9UPT5,Q86Y37 2 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0.3742421704584036 0.2378167231813901 0.8120232475136102 1.0 0.9396939546371372 5 P52292,O60684 2 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3299747328886476 0.2285308295948932 0.8192335916086204 1.0 0.9437113896013508 16 Q9NYU1,Q10472,Q9NR50 3 +Tautomerase/MIF superfamily [IPR014347] 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.9478212623224668 2 P30046 1 +Ribokinase-like [IPR029056] 0.4820208023774162 0.2069274823785776 0.83606649316291 1.0 0.9548423787952044 3 Q9BRR6,P55263 2 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.4925727866904472 0.2039485388948706 0.8383937135932238 1.0 0.9548423787952044 2 P54136 1 +S15/NS1, RNA-binding [IPR009068] 0.3565269104965894 0.2036009103514744 0.8386653816873444 1.0 0.9548423787952044 5 P41250,P56192,P23381,P07814 4 +50S ribosomal protein L30e-like [IPR029064] 0.3395833333333355 0.2020268854916639 0.8398957059387602 1.0 0.9548423787952044 8 P62888,P62495,P25398,Q9BRX2,Q9NX24,Q9HC36,P55769 7 +Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825] 0.4863339275104045 0.1953556468874435 0.8451145362423558 1.0 0.9558866110492634 2 Q8N1G4 1 +KA1 domain/Ssp2, C-terminal [IPR028375] 0.4759358288770194 0.1820781347004335 0.8555214078786022 1.0 0.9625527616543404 2 Q7KZI7 1 +Gelsolin-like domain superfamily [IPR036180] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.9625527616543404 5 P53992,Q15436,O95487,Q15437 4 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.3437407077014645 0.1817025792384766 0.8558161417306323 1.0 0.9625527616543404 5 P53992,Q15436,O95487,Q15437 4 +Ribosomal protein L22/L17 superfamily [IPR036394] 0.4682115270350634 0.1730417704082018 0.8626185948006082 1.0 0.966329002121766 2 P18621 1 +Histone deacetylase domain superfamily [IPR037138] 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.966329002121766 2 Q92769 1 +SGNH hydrolase superfamily [IPR036514] 0.4652406417112443 0.1697498402872916 0.8652068759426852 1.0 0.966329002121766 2 Q15102 1 +Nucleoside diphosphate kinase-like domain superfamily [IPR036850] 0.4616755793226506 0.1659318640914314 0.8682105711660852 1.0 0.966329002121766 2 P15531 1 +Cullin homology domain superfamily [IPR036317] 0.3233194527067131 0.1602680803612778 0.8726699020032556 1.0 0.966329002121766 6 Q13619,Q93034,Q13620,Q13617,Q13618 5 +Zinc finger, CCHC-type superfamily [IPR036875] 0.4374442793462127 0.1544220427164765 0.8772769745389009 1.0 0.966329002121766 3 Q16629,Q9NUD5 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.449494949494958 0.1539487596296621 0.8776501377066168 1.0 0.966329002121766 2 P35611 1 +Moesin tail domain superfamily [IPR008954] 0.340368608799038 0.1469208794416481 0.8831944713489663 1.0 0.966329002121766 4 P35241,P26038,P15311 3 +TGS-like [IPR012676] 0.3135038667459759 0.1441010160052478 0.8854207024402723 1.0 0.966329002121766 6 Q9NTK5,P55039,P26639,Q9Y295,Q9BW92 5 +HSP20-like chaperone [IPR008978] 0.3024986711561001 0.1421390827062198 0.8869701480257253 1.0 0.966329002121766 11 Q8IVD9,P04792,Q96RS6,Q15185 4 +Beta-grasp domain superfamily [IPR012675] 0.3135971437072347 0.1419750394010892 0.8870997216168024 1.0 0.966329002121766 7 Q9BW92,Q9NTK5,P21912,P55039,P26639,Q9Y295 6 +Anticodon-binding domain superfamily [IPR036621] 0.3353151010701486 0.141927792943085 0.8871370409397217 1.0 0.966329002121766 4 P26639,P41250,P07814 3 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.3317479191438705 0.1385806973404583 0.8897814974038833 1.0 0.966329002121766 4 Q9BXS5,P48444,Q96CW1 3 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.4307783719548476 0.1385629269344414 0.8897955406568443 1.0 0.966329002121766 2 Q6GMV3 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.4171010779028914 0.1370465321810009 0.8909940147114019 1.0 0.966329002121766 3 Q9BRT9 1 +Ureohydrolase domain superfamily [IPR023696] 0.4136701337295711 0.1344882865541616 0.8930164729200352 1.0 0.966329002121766 3 Q92769,Q13547 2 +NTF2-like domain superfamily [IPR032710] 0.3091364320273083 0.1342139052150823 0.8932334306242435 1.0 0.966329002121766 7 P61970 1 +ESCRT assembly domain [IPR037202] 0.4080237741456185 0.1305002041559704 0.8961706926310395 1.0 0.966329002121766 3 Q99816,Q9UK41 2 +Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149] 0.316056263520209 0.1255317325862781 0.9001026047551202 1.0 0.966329002121766 4 Q9NQW7 1 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.3934621099554254 0.1214303062569022 0.9033502135641804 1.0 0.966329002121766 3 Q96HP0,Q14185 2 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.3934621099554254 0.1214303062569022 0.9033502135641804 1.0 0.966329002121766 3 Q96HP0,Q14185 2 +RNA polymerase, RBP11-like subunit [IPR036603] 0.400475341651823 0.1205053647086975 0.9040828301926752 1.0 0.966329002121766 2 O15160 1 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.400475341651823 0.1205053647086975 0.9040828301926752 1.0 0.966329002121766 2 O15160 1 +Serpin superfamily, domain 1 [IPR042178] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.966329002121766 2 P35237 1 +Serpin superfamily, domain 2 [IPR042185] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.966329002121766 2 P35237 1 +Serpin superfamily [IPR036186] 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.966329002121766 2 P35237 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.3848439821693926 0.1168352635780069 0.9069905988133578 1.0 0.966329002121766 3 O60884,P31689 2 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.3835405607750695 0.1161873577420897 0.9075040559526996 1.0 0.966329002121766 3 Q9BYT8 1 +Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591] 0.3903743315508098 0.1160972297239747 0.9075754843287428 1.0 0.966329002121766 2 P08865 1 +GAR domain superfamily [IPR036534] 0.3877005347593669 0.1150478641102014 0.908407183812769 1.0 0.966329002121766 2 Q03001 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.3823529411764864 0.113087452588116 0.909961222559865 1.0 0.9669545475397292 2 Q13188 1 +Ribosomal protein L11, C-terminal domain superfamily [IPR036769] 0.3657159833630494 0.1080621065170561 0.9139464267015992 1.0 0.9672797403930874 2 P30050 1 +Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796] 0.3657159833630494 0.1080621065170561 0.9139464267015992 1.0 0.9672797403930874 2 P30050 1 +DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599] 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.9672797403930874 2 P18858 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.346405228758178 0.1039424636939488 0.9172150084414183 1.0 0.9672797403930874 2 P46782 1 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.32412358882948 0.1009136852659135 0.9196189792964826 1.0 0.9679690833604406 2 P49588 1 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.2328823891760268 0.0814034811027197 0.9351210807811774 1.0 0.9794527734524756 5 P15170,O00178 2 +AH/BAR domain superfamily [IPR027267] 0.2787409280056803 0.0656407205392296 0.9476638687023902 1.0 0.9871087747878174 14 Q9UKS6,O95219,Q13596,O60749,Q9UNF0,Q9UQB8 6 +SH2 domain superfamily [IPR036860] 0.2740008083831082 0.0532321161580834 0.9575469668889568 1.0 0.9963664385195904 14 P62993,O00459 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.2829420635364664 0.0330765022342273 0.9736135809952626 1.0 1.0 20 Q8IWZ3,Q13418,O75179,O75832,Q86XL3,Q04721 6 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..af621742d525564e2c19bdc70408967519a13812 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-dystroglycan domain 2 [IPR027468]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase delta subunit 3 superfamily [IPR041913]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Presenilin, C-terminal [IPR042524]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Rad4, beta-hairpin domain 3 superfamily [IPR042488]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transglutaminase-like superfamily [IPR036985]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain [IPR044920]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARMC10", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATRX", "ATXN10", "ATXN2", "AURKA", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCKDHA", "BCKDHB", "BCL2L12", "BCL2L13", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BROX", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPV", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHTF18", "CIAPIN1", "CIB1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FAT1", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED25", "METAP2", "METTL13", "METTL14", "METTL16", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCKIPSD", "NCL", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NENF", "NEO1", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGG", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIL1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STAT1", "STAT3", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX12", "STX17", "STX4", "STX5", "STX7", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TATDN1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM131", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBLCP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UGDH", "UGGT1", "UGGT2", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS26B", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR82", "WDR89", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP73", "WRNIP1", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB33", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF281", "ZNF292", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZZZ3"], "leading_proteins": ["AARS", "ABCB1", "ABCC1", "ADD1", "ADGRE5", "ADK", "ADPGK", "AIFM1", "ALCAM", "ANKHD1", "ANKLE2", "ANKRD17", "ANP32A", "ANP32B", "AP1B1", "AP1M1", "AP2M1", "APLP2", "APRT", "ARCN1", "ARFGAP1", "ARHGAP1", "ATG7", "BAG4", "BAIAP2", "BRD3", "BROX", "BSG", "CACUL1", "CALU", "CAPZB", "CCNB1", "CD109", "CD320", "CD47", "CDH2", "CETN2", "CFL1", "CHAC2", "CLCN3", "CNNM4", "COLEC12", "CPD", "CPVL", "CRK", "CTNNAL1", "CTPS2", "CTSA", "CTTN", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWF19L1", "CXADR", "DBNL", "DCPS", "DDT", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DOCK1", "DOCK6", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DUSP3", "DUSP9", "DYNLL2", "ECE1", "EEF1B2", "EFCAB14", "EHD1", "EHD4", "EIF2B3", "EIF5", "EMB", "ENO2", "EPHA2", "EPHA7", "EPHX2", "EPRS", "EPS15", "ETF1", "EXO1", "EXOC7", "EZR", "F11R", "FAM120A", "FAT1", "FCGRT", "FDXR", "FKBP9", "FOXRED1", "FUCA1", "FUCA2", "GAA", "GAK", "GALNT1", "GARS", "GBA", "GGH", "GGT7", "GINS4", "GLA", "GLB1", "GLB1L2", "GLOD4", "GMFB", "GRB2", "GSPT1", "GTF2H1", "GTPBP1", "HDAC1", "HDAC2", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGB3", "HPRT1", "HSP90AB1", "HSPB1", "IGF2R", "ILK", "ILKAP", "IQGAP3", "ITCH", "ITGAV", "IWS1", "KDM1B", "KIAA0319L", "KPNA2", "KPNA6", "LASP1", "LDLR", "LIG1", "LIPA", "LNPEP", "LPCAT2", "LRIG2", "LRP1", "LRRC47", "M6PR", "MAN2B1", "MAN2B2", "MAPRE1", "MARK2", "MARS", "MCAM", "MFGE8", "MINDY3", "MOCS3", "MPP2", "MRC2", "MRM3", "MSH2", "MSN", "MSTO1", "MTMR14", "NAE1", "NAGLU", "NAP1L1", "NAP1L4", "NCAM1", "NECTIN2", "NEDD4", "NEDD4L", "NENF", "NEO1", "NHP2", "NISCH", "NLN", "NME1", "NOTCH2", "NPC2", "NPEPPS", "NRP1", "NSD2", "NUCB1", "NUCB2", "NUDCD1", "NUDCD3", "NUTF2", "OLA1", "PABPC4", "PACSIN2", "PACSIN3", "PAFAH1B3", "PALD1", "PCDH7", "PCYOX1", "PDE6D", "PELO", "PFDN5", "PFKM", "PFKP", "PFN1", "PGM1", "PGM3", "PIK3R2", "PKN1", "PLA2G15", "PLXNA1", "PMPCA", "PNP", "POLA1", "POLD1", "POLR1C", "PPT1", "PPT2", "PRCP", "PREPL", "PRKAR1A", "PRPSAP1", "PRTFDC1", "PSMA3", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PTGES3", "PTPRF", "PTRHD1", "RACGAP1", "RAPGEF2", "RARS", "RB1", "RCN2", "RDX", "ROBO1", "RPL12", "RPL17", "RPL30", "RPS12", "RPS5", "RPSA", "SAMHD1", "SCPEP1", "SDHB", "SEC23A", "SEC23B", "SEC24B", "SEC24C", "SERPINB6", "SET", "SEZ6L2", "SKP2", "SLC25A20", "SLC25A33", "SLC33A1", "SLIT2", "SMAP1", "SNU13", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX4", "SPNS1", "SRP14", "SRSF7", "STK3", "STX12", "STX17", "STX7", "SV2A", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCB", "TLN1", "TOX4", "TPBG", "TRIM26", "TSG101", "TSNAX", "TSPAN3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP3", "TWF2", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2N", "UBE2O", "UBE2S", "UFC1", "UGGT2", "USP33", "VCL", "VPS28", "VTI1B", "WARS", "XPNPEP1", "YWHAE", "YWHAQ", "YWHAZ", "ZCCHC3"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f4c58d271e4f87657097817581bce68785f1e615 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0943d0a7a64c3f5cade3875efde6dcd7fffc489f5ca5e484d23aed0d3cdbbbee +size 75350 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..303037541f28e6e3651804c26dc2d2f312763455 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 4 6 2.459003237015357 0.0139323361585412 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 1.1245333568397323e-05 0.0007667347448651 2.788863476938184e-05 0.0019200914773881 0.0083426651664859 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7e39f1e5a06fe41bc6ac98c858770e77dbab9885 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fa525d6ffea244f9d66ec985d4a90712daaed8d7 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c2212815b7acbf1a69d17f25544d90faedee40fa --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.9573548133831954 2.459003237015357 0.0139323361585412 0.0545754646330451 0.0278646723170825 6 P01130,P48960,Q07954,Q14517 4 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..abd472f70edb3361fc6b27006a6247d654aafa88 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ADGRE5", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "EIF5A", "FASN", "FAT1", "LDLR", "LRP1", "NOTCH2", "SLIT2"], "leading_proteins": ["ADGRE5", "FAT1", "LDLR", "LRP1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2bbde2dbc5f45ed6e9638558ee7f0d00d7a03a7f --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Leucine-rich repeat [IPR001611]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..81b52eedf36feacbeef4941dd77bb4334c37c721 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f4a2ba7fd4c4872a79df2c284884f224c852f31e4e0aa8e562d1c95a5871c86 +size 191372 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2bbde2dbc5f45ed6e9638558ee7f0d00d7a03a7f --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Leucine-rich repeat [IPR001611]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9cc375dc1ba98d923d11c9b90d6c6df00cb29ff8 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e495475906c44b4a2aac6a2123a532f60b494aa7d8b9a1d10dfdd33b142c5c53 +size 134245 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0cd97d01b9303f3e1a2dac9508843a0d86dc4c39 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94790f0dab528b57e5310dbca12adecfdcaafa70b701d0a28feb7d85656d0163 +size 87102 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ee255ba37c7fa719bedbc1db4935544d3f962db2 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Leucine-rich repeat [IPR001611] 6 24 2.457516410633983 0.0139901418716295 7.927184466019417 22.259708737864077 -0.5290763430780047 0.5250385114343609 3.7610082870028783 3.927501727317124 0.8396929859577328 0.309306312678558 0.1635242481649697 1.0 0.2171594264364444 0.0059914172581948 0.068025221638467 +Leucine-rich repeat, typical subtype [IPR003591] 2 16 2.3005754648148717 0.0214156391843558 4.490291262135922 13.313106796116504 -0.3794289556948225 0.5646814188290152 2.6635626395081915 2.79241744769417 0.7830924352126281 0.2956886956400376 0.0784025564630051 1.0 0.1075014480598519 0.1623088290800169 0.3018020125798973 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..056b17d2875988cbe912be86a243e5689a64ed06 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 79, + "title": "Average number of proteins per term", + "value": 5.518987341772152 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..587679ce87499b5c9fae7082f5ff41a9e90c688d --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3418274fc9ec06261acaaad74b3ca4d0ebbbe789 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Leucine-rich repeat [IPR001611] 0.7073966448893008 2.457516410633983 0.0139901418716295 0.6714365075704685 0.0851916755075639 24 O94898,O94813,P39687,Q13641,Q92688,Q9Y2I1 6 +Leucine-rich repeat, typical subtype [IPR003591] 0.7368048473624162 2.3005754648148713 0.0214156391843558 0.819172950740856 0.0851916755075639 16 O94813,Q13641 2 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.986645789343353 2.2365583556630715 0.0253152192802028 0.8680921629726068 0.0851916755075639 4 P01130,Q9NPF0 2 +LDLR class B repeat [IPR000033] 0.989007724301842 1.8588919748613963 0.0630424518487777 0.9941672518478334 0.1749212207233814 2 P01130 1 +Proteasome/cyclosome repeat [IPR002015] 0.7225193107546097 0.8213657098614703 0.4114379892637232 1.0 0.6019185398487803 2 Q13200 1 +Mitochondrial substrate/solute carrier [IPR018108] 0.3649889666147593 0.40847260208742 0.6829267411024893 1.0 0.8052419783148754 20 O43772,Q9BSK2 2 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.5408618127786048 0.3088134287205674 0.7574634534644469 1.0 0.8548516117670186 3 Q8WUH2,Q9P253 2 +Leucine rich repeat 4 [IPR025875] 0.532243684992572 0.2915749599601582 0.7706116229521855 1.0 0.8574411015946853 3 Q9UFC0,Q8N1G4 2 +Atypical Arm repeat [IPR032413] 0.3742421704584036 0.2378167231813901 0.8120232475136102 1.0 0.890969952132989 5 P52292,O60684 2 +Calponin repeat [IPR000557] 0.4222882615156036 0.1411131599695948 0.8877805475312066 1.0 0.941839630724545 3 Q99439,Q15417 2 +Tetratricopeptide repeat 2 [IPR013105] 0.2862663495838251 0.1075337295849497 0.9143655681111164 1.0 0.941839630724545 4 Q13325,Q02790,P31948 3 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e2e4f194b4cdc93a05282b782839fcc807e7ba35 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "RPEL repeat [IPR004018]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMCX3", "ARPC1A", "ARPC1B", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DMD", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA6", "ITGAV", "JUP", "KAT7", "KDELC2", "KDM2A", "KDM2B", "KIAA1468", "KIDINS220", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "L3MBTL2", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MKL2", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PKP2", "PLAA", "PLEC", "PLRG1", "PLXNA1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP4", "RBBP5", "RCC1", "RCC2", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STRN4", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TENM3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TP53BP2", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UACA", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", 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1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 4.997384237337058e-07 1.0300351750963514e-05 5.6969819732787125e-09 1.759622064330642e-07 4.711144425192826e-06 +Vacuole organization 16 61 3.219408607979393 0.0012845530019245 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0002586258449086 0.0009290843179327 2.010399538094132e-05 0.0001055276825842 0.0005336316718659 +Phagocytosis 11 44 3.219073477073497 0.0012860552661679 8.633495145631068 38.567961165048544 0.0319038557979206 0.6898951952307567 4.3297508187988205 5.612290839266196 0.7929688055011034 0.2962152733283993 0.0003524968576763 0.0024477331896819 1.715326904083724e-05 0.000121000317906 0.0041705007305582 +Positive regulation of response to external stimulus 17 68 3.199217334989241 0.0013780124374946 14.03640776699029 59.237864077669904 -0.0988246792844902 0.6482245236244654 5.442206033708916 6.922365840945858 0.8603956617533591 0.3163763423285246 0.0006594795625647 0.0587615611733179 0.0019764197885788 0.0001373530530939 7.26633788608951e-06 +Cell cell adhesion via plasma membrane adhesion molecules 14 19 3.1942659100527147 0.0014018692602171 4.393203883495145 13.847087378640778 -0.0813937198729435 0.5364725215394986 2.8139307454137743 4.13819718991933 1.0044807738527848 0.3140901937753358 0.0281740632520034 0.0597604037758126 0.0450913351422118 8.330365428307427e-10 7.000532333070448e-06 +Transmembrane receptor protein serine threonine kinase signaling pathway 16 48 3.180009208020972 0.0014727037258674 10.631067961165048 46.15291262135922 0.2006852178393374 0.6675090539046344 4.897969246836294 6.113284616160956 0.8079382077361186 0.3228563247928272 0.0055683384589375 0.0161114981694795 0.0134142100600963 0.0551918016716766 0.0038654968924716 +Membrane lipid metabolic process 10 38 3.0969804141786037 0.0019550279042701 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 5.070724417347723e-07 2.4407136963387777e-05 2.481556934654252e-07 0.0001639845862835 0.0055672965698184 +Anatomical structure homeostasis 10 42 3.086467244976431 0.0020255026129347 8.04611650485437 37.74757281553398 -0.8265793858068656 0.3669467507401432 3.743643086519086 4.240279452693054 1.2249317969197393 0.3202756345948493 0.0097165405677541 0.0434644049612363 0.004818495856418 0.0018635934486991 0.0243193515283451 +Neuron death 21 79 3.083214982412334 0.0020477716281246 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 0.1056256871896054 0.0938642261720824 0.0213825549118818 0.0197233786286683 0.0025986463806794 +Neuron apoptotic process 17 50 3.071788229822083 0.0021278062463157 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.0324095800345172 0.0357664341382327 0.0150628386019023 0.0033642645861238 0.0008556056882652 +Locomotory behavior 7 28 3.0707246141201487 0.0021354000336908 7.186893203883495 29.01456310679612 0.367578136549174 0.4129867938447028 2.855164467106169 2.964970497634466 1.254834886476281 0.3178953925587394 0.000118245663178 0.0111951113174208 3.8564244843452064e-05 0.0005044535466369 0.0170591920619043 +Regulation of blood pressure 3 19 3.065703269622048 0.0021715871117502 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0012401971399596 0.0001786553420583 0.0024636847742138 0.0528261722730647 0.3129479757165558 +Cell morphogenesis involved in differentiation 51 144 3.0625646976351493 0.0021944903142956 30.27912621359223 122.126213592233 -0.1867286336625038 0.641278511812741 12.483085690754145 13.9865952550349 0.8140610053379778 0.3158474092010998 0.0824046706120102 0.075227329424044 0.0376164978497803 0.0001619963949045 0.0001434119051027 +Sphingolipid metabolic process 9 28 3.0312821401518857 0.0024351758301908 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 8.641093200885211e-07 9.134926391858884e-05 3.115090573072523e-07 9.4059875687442e-05 0.0058601021721165 +Sterol metabolic process 13 41 3.0275714922494896 0.0024652739197075 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 0.0006235932260289 0.0082661149627475 1.6673556615896856e-06 1.5119657667001427e-08 1.2912647045240088e-05 +Aminoglycan metabolic process 8 14 2.996020065535786 0.0027352843422621 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0001423684491126 0.0002315417538986 3.0184002389216613e-05 1.7527360716197133e-05 0.0029211533393603 +Negative regulation of response to external stimulus 15 48 2.986337400675528 0.002823409409407 9.381067961165048 47.019417475728154 0.8063071074275461 0.4700507256615295 4.127569023520378 6.3589713134688575 0.9364755672970396 0.3491987458588393 0.1627057717161648 0.5716144790158193 0.0262919387511793 0.0009803404033542 0.0016826305416249 +Homophilic cell adhesion via plasma membrane adhesion molecules 11 14 2.9832615433248795 0.0028519417093164 2.9805825242718447 8.54368932038835 0.0091284588498221 0.5023151287276502 2.0959071651987573 2.502529590250657 1.0648724046913465 0.3160038827031496 0.0069121244314848 0.0230307909850112 0.0115064399741943 1.103834827833574e-09 2.200538979878468e-06 +Cell recognition 8 26 2.9790675642356983 0.0028912701762113 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.0133377930203514 0.0358926009784828 0.0029632963559562 0.0001087627785303 0.0026068114295301 +Regulation of nervous system development 26 72 2.9655414198781247 0.0030215065532894 12.805825242718448 63.61407766990291 0.2155377588210499 0.7082353007711337 6.12064507741093 7.878266520790482 0.7102203562190534 0.3141420063295854 0.0513905127941958 0.3443282275566168 0.0964817355259891 0.0409018063049507 0.004806752934768 +Transmembrane receptor protein tyrosine kinase signaling pathway 17 80 2.962349044964717 0.0030530147173406 16.08009708737864 77.06067961165049 -0.0485627927051033 0.6938858681640644 6.537486526767104 10.47367052639186 0.6879809976691484 0.2993517001027577 0.2942285868247685 0.0824567482863823 0.4222375833123436 0.0696463337394621 0.0994212744208958 +Response to growth factor 31 112 2.943635348251436 0.0032438194983173 23.660194174757283 102.07038834951456 -0.1027882800096403 0.6500127575071359 9.638669486856536 13.591023481204804 0.8391550653072546 0.3197498193445682 0.0160805828506057 0.0457005105145347 0.0429613648163609 0.066670827589306 0.0021811932212675 +Leukocyte proliferation 9 39 2.937141917499437 0.0033125247551628 8.162621359223301 37.15291262135922 0.2981832216609602 0.6690469371584539 3.79131108330846 4.341425682138302 0.7402794541786957 0.3092217445894261 0.0253467223975825 0.0293962749000691 0.0110705878241367 0.0063616232528828 0.070832822352764 +Positive regulation of locomotion 17 88 2.927870613849823 0.003412920381703 17.813106796116504 82.76941747572816 -0.0202856110636012 0.6872652647880098 6.785301293884359 10.926397031402892 0.7474886342310336 0.3042029503813403 0.2295672238560694 0.4369125326883025 0.0282931044995453 0.0158040830434131 0.037576633887991 +Cognition 7 39 2.9143078406737204 0.0035647819386912 8.381067961165048 35.51456310679612 0.106014143429431 0.585314562092836 3.4293041589801794 4.867395144092575 0.9639094447868622 0.3250247192097197 0.0002028644335715 0.0059901365409964 0.0006363537534215 0.029602951883941 0.1112060833876222 +Cell chemotaxis 16 41 2.913550153328397 0.0035734443103971 9.135922330097088 37.060679611650485 -0.0784030605852576 0.6324652441331359 4.405531703007072 4.1435067372718635 0.8456116765533065 0.3122963338427361 0.0590712260341631 0.4164957533300368 0.0915328142013738 0.0003221596677165 7.125210100114319e-05 +Regulation of neuron projection development 24 85 2.879259568855681 0.0039861010671566 13.592233009708735 69.32038834951456 0.4627708713262993 0.6269884749906404 5.824182751460114 9.346058399998094 0.798447623110489 0.3496779713708587 0.3820649249555202 0.7421235934024417 0.2773985925778649 0.0010301675691369 0.0003422811587161 +Biological process involved in symbiotic interaction 22 87 2.8749218694097216 0.0040412748700202 16.524271844660195 76.43932038834951 -0.5010535102907213 0.5207152694072219 8.300596142112324 6.579514214979575 1.032159450203337 0.3396665187616686 0.0006173084809541 0.0017630110348898 6.250093732822483e-05 1.3023890847760361e-08 1.427494615956289e-07 +Membrane lipid catabolic process 7 11 2.866160286994415 0.0041548381906675 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 8.573081055531122e-09 2.3399875141854645e-06 4.929409740362843e-10 1.1057177661886282e-08 2.25771078565684e-06 +Organophosphate ester transport 9 29 2.8575887116594005 0.0042687329261199 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0038604283195994 0.0005866199897207 0.0010419295639301 0.0006606370484741 0.0048410909429686 +Blood vessel morphogenesis 15 85 2.856729463425794 0.0042803049181912 16.385922330097088 77.21116504854369 -0.0973321885149326 0.6747953299436705 6.598329876492682 9.741890907235984 0.7122561449451958 0.2968219097091266 0.1274442354293214 0.2155749187316888 0.0414696059859801 0.0142771715126116 0.2454468702140083 +Ameboidal type cell migration 17 81 2.855117199122492 0.0043020950076593 13.730582524271844 74.04126213592232 0.129572976857371 0.704489733767973 6.782167984744024 8.272996566747787 0.7243120611140652 0.3130633389064787 0.0629815602618123 0.13795486567134 0.0444217325208098 0.0124391526314604 0.0557755374920231 +Endothelial cell migration 11 39 2.8526377246640493 0.0043358019593779 6.412621359223301 35.5752427184466 0.4082848327362888 0.5352947559852537 3.4640505952618645 3.829708687407978 0.952730213605329 0.3344080805283456 0.0925591216823525 0.1366182888425317 0.040634807083858 0.0014465221223256 0.012096990364918 +Receptor metabolic process 8 37 2.8434906467750536 0.0044622319077634 8.254854368932039 34.48300970873787 0.1190654259323194 0.6256821363336791 3.854212262351103 4.138641335837385 0.844404065510763 0.3109475309665375 0.0014849208064248 0.0001409428662617 0.003364879438832 0.0401462700952276 0.0114575734656985 +Viral life cycle 24 105 2.839218748331739 0.0045224142731008 19.410194174757283 93.29611650485435 -0.3045293626460413 0.6588462721769274 10.482263936948428 7.880459085859297 0.7518829773930114 0.3155541175306531 0.0312184309043078 0.0890790787301206 0.0052635237334961 1.3246697116574243e-06 1.884788015147951e-07 +Cell part morphogenesis 50 138 2.8372555542288542 0.0045503175124299 26.983009708737864 118.6019417475728 0.0053227567796788 0.7443384780209938 11.4203532612418 14.976414989521164 0.7256117492835441 0.3075338103498531 0.1405257022126673 0.1616608674845378 0.1324247804751947 0.0003766868355637 6.925035293468078e-05 +Secondary alcohol metabolic process 12 45 2.836897811041656 0.0045554189481209 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 0.0006936057453806 0.0088103554061084 2.173820466111822e-05 1.6501883975073565e-07 1.7273306486437814e-05 +Protein maturation 16 82 2.835500208677353 0.0045753985182792 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0012201653666371 0.0029218389647841 0.0007831431684808 0.0038114634153238 0.0092983401263268 +Regulation of response to external stimulus 45 142 2.823391500130778 0.0047518506642694 27.32766990291262 129.63349514563106 0.3937649860570471 0.6986677015868525 9.316542933972368 15.399506498758855 0.8616366228871625 0.3591499966721317 0.0084027709355886 0.1616608674845378 0.0033559693018608 2.0071307547104423e-05 4.3814314130724187e-07 +Regulation of defense response 31 97 2.8226264098846894 0.0047632040140237 20.351941747572816 89.95145631067962 0.3090454403231809 0.6824878992411626 7.399483130499616 11.222488380567595 0.777906173710776 0.3278161680699026 0.0932702463035745 0.1767081432445665 0.0261364276395485 0.0009417341897379 1.85507655053185e-05 +Adult behavior 6 20 2.814159200469514 0.0048905002138328 4.924757281553398 19.364077669902912 0.6031935344655648 0.4116465050786389 2.137657889318908 2.190772988063693 1.071812274679601 0.3090358289458393 0.0001782921624544 0.0402962873689797 0.0004254356855182 0.0009914642019716 0.0132089705588992 +Establishment of protein localization to vacuole 3 18 2.809052208431243 0.0049687588117024 4.521844660194175 17.024271844660195 0.4258363140243343 0.4350316278309467 2.7059819557420526 3.223757863278806 1.1181009658786627 0.3126979331758455 0.0044373898287515 0.0010375212435442 0.0074499229745329 0.0173259681631819 0.1376237189726102 +Carbohydrate catabolic process 5 49 2.802385435002108 0.0050726229412747 13.45631067961165 48.04854368932039 -0.4023701280258725 0.4815028531235779 7.512483719225854 3.3199270104758867 1.2356914704034725 0.3542406229670218 0.0017582107736204 0.0966324665930835 0.0006224264999654 0.0468934279705003 0.1506431916840714 +Nervous system process 26 109 2.795625314221712 0.0051799415598237 23.060679611650485 100.46844660194176 0.466210961761844 0.5050785047376438 7.1617042179301365 12.55034423055404 1.1784062094355452 0.368401069133876 0.0004617302586842 0.0145119926311301 0.0001750360021283 0.0116694404183213 0.0443050159886513 +Regulation of system process 9 68 2.7925488186600305 0.0052294575914255 12.432038834951456 59.63106796116505 0.142870153937744 0.6256858745623561 5.047131523930307 6.726256754497268 0.8769607822191469 0.3283787852153951 0.0076939145282125 0.0862598446229127 0.0181868424946348 0.036134825021278 0.2400334148321739 +Protein localization to lysosome 3 16 2.784873333153673 0.0053548637048967 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 0.0033107591961438 0.0007667347448651 0.0055856505984271 0.0121856638082503 0.1040239469578102 +Transition metal ion homeostasis 5 27 2.781541076992846 0.0054101483649362 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0004717556690673 0.0069945898038035 0.0011028577372738 0.0133275956191841 0.094428031243587 +Protein targeting to vacuole 3 16 2.765033950791348 0.0056916871599463 3.9441747572815538 15.055825242718448 0.398430957984614 0.4200771820268876 2.3315668402653484 2.59373592845287 1.1496285974512008 0.311969859629291 0.0025948332275146 0.0005966319628977 0.004393919895815 0.0090567827451286 0.0816645346360282 +Liposaccharide metabolic process 6 16 2.7638512507970048 0.0057123573552522 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0001034090061428 0.0028326312129738 2.0511483695854597e-05 0.0004948612164357 0.0067400711985061 +Protein localization to vacuole 3 21 2.758993629597458 0.0057979665203862 5.20873786407767 20.24757281553398 0.5437651170857908 0.3970016112497027 2.9079938968471533 3.678442701839641 1.178287503307516 0.309681546976434 0.0110979142419323 0.0026953565990113 0.0182749379957494 0.0501037692041591 0.3018020125798973 +Mononuclear cell migration 7 26 2.757261914829877 0.0058287642958056 6.058252427184466 23.645631067961165 0.0105016163762546 0.6303901682999394 3.102067092594892 2.7844323365283423 0.8660601863335294 0.3059427019687199 0.0164750798700994 0.0414278249847813 0.0268391045488713 0.0053374430593766 0.0012458006436326 +Phospholipid transport 6 14 2.755877523259441 0.0058534910763563 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0007626845241698 0.0001079185290087 0.0001348318070603 0.0002202866177203 0.0112872973833843 +Negative regulation of cell differentiation 16 79 2.732084005390086 0.0062935091955573 16.45631067961165 74.8495145631068 -0.1353149290741099 0.6688900030125019 8.66672769349464 8.561410075612406 0.7355667191532931 0.3072250429225737 0.2923927773855387 0.0817634735159642 0.2337148002162704 0.0361045629611482 0.0971276389216833 +Gliogenesis 11 55 2.726304093020889 0.0064047960725688 10.57766990291262 53.11407766990291 0.3128888864166735 0.6283481078716698 4.440686381801957 5.34345583548812 0.8423545321673526 0.3276548637936928 0.0453917667847182 0.0468986791976777 0.0229642576541285 0.0198305799367777 0.0147334210702469 +Neuromuscular process 6 29 2.7179699855857544 0.0065683796228834 6.682038834951456 25.487864077669904 0.5107907507501308 0.3958015985368521 2.5973040014911133 3.0533044809467955 1.2106508695866462 0.3144907539964949 0.0020055888519234 0.0414278249847813 0.0004567644770011 0.0010864364912465 6.98000131723506e-05 +Positive regulation of inflammatory response 6 16 2.717070034507863 0.0065862669372012 3.71116504854369 12.604368932038836 -0.2371758915201458 0.5181114568213592 2.0280967216986476 2.002736075028172 0.9629686677278052 0.3077182349956747 0.0073202198372533 0.0239365913087713 0.0121710399777804 0.0011585880107859 0.0091015487948519 +Regulation of steroid metabolic process 4 14 2.7161646816127183 0.0066043058047331 4.334951456310679 14.769417475728156 0.4748357054552781 0.3599056508632772 2.2294240946396933 1.955260926764874 1.2378399088740557 0.2930403635554361 0.0008211635363398 0.0267403422938185 0.0016441077117893 0.0085171031160944 0.1079287008920704 +Peptide catabolic process 4 12 2.712805538585533 0.0066716245078075 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0004587899988766 0.0001017478453213 3.0155128003151412e-05 7.329957165203042e-05 0.0002049367226 +Leukocyte migration 11 51 2.7042721186244147 0.0068454204860566 10.118932038834952 46.80582524271845 0.3575882448711393 0.6313812887885496 4.534434682359551 5.391125848207169 0.8213013384586727 0.3308801783294869 0.1006956313400111 0.145012854682081 0.1512218115452644 0.0019118285521962 0.0068680599881591 +Regulation of peptidase activity 17 87 2.7036170326794893 0.0068589289583618 17.567961165048544 78.76456310679612 0.2681055370567821 0.6519293611165848 6.220288033667961 7.048060158198876 0.8199709838080707 0.3419859398793775 0.009735054137188 0.0237483770729725 0.0063961174121688 0.000387996578676 0.0002346898937043 +Negative regulation of cell development 6 26 2.6987804826480537 0.0069594065126643 4.842233009708738 22.570388349514563 0.359297279383123 0.4985276743183016 2.6202836250687755 3.2526907225500694 0.942582430028218 0.3017948582790589 0.1780068489281796 0.0774829110890059 0.235253462083624 0.0798509231648122 0.0873094135982188 +Vascular transport 6 18 2.6935921935045486 0.0070686593245039 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.0077423266250305 0.0018494623097264 0.0128572972549699 0.000194035076238 0.0101516407294213 +Glial cell differentiation 9 41 2.6916734973660112 0.0071094508734286 9.114077669902912 39.55582524271845 0.0390069906662089 0.6900510842485431 4.944752624574786 4.36438476947918 0.7800237575091793 0.3056622158259627 0.0188097762304914 0.0232059299134093 0.0343021791505057 0.0333776500869942 0.018715330705788 +Negative regulation of nervous system development 6 20 2.685302047086742 0.0072464285992077 4.225728155339806 17.99514563106796 0.4680685636974716 0.419713233745777 2.1977522064718618 2.960086545598349 1.0442754970945465 0.2873726818408866 0.1325482656466103 0.0559003563721154 0.1779321056766125 0.0417227578986097 0.0356114340213217 +Regulation of synapse structure or activity 12 36 2.6851370956064997 0.0072500060767421 6.665048543689321 33.640776699029125 0.4177416009353497 0.6162292560215563 4.025337439581666 3.7073905955276114 0.8008691737125054 0.3301048213868146 0.0771722421196986 0.1201931014379405 0.1178397981991102 0.07815743447109 0.0063939412457931 +Protein targeting to lysosome 3 13 2.684092964426943 0.0072726880484508 2.861650485436894 11.133495145631068 0.4665494631806399 0.3733123029661771 1.8767316131355816 1.7651272451933906 1.2080503341010538 0.3026029882111192 0.0006223592227998 0.0001386921185947 0.0010709052035729 0.0014975917181939 0.0172333771485565 +Regulation of leukocyte proliferation 7 26 2.680161756888144 0.0073586591288954 5.752427184466019 23.393203883495147 0.3932260927985178 0.5806940436166351 2.797687833832017 3.7032853987829895 0.8370636232955005 0.3221548844899082 0.0455644056464018 0.0121763996061447 0.0155897140308576 0.0100095940368711 0.0491284122265348 +Neuromuscular process controlling balance 4 13 2.678721166637001 0.0073903907632801 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 4.533849025767395e-05 0.0065792573185243 3.7314265804019496e-06 0.0002970801321964 0.0010422272070108 +Positive regulation of defense response 11 47 2.672674820510601 0.0075249154297103 9.526699029126211 39.58495145631068 -0.1121342674830764 0.6770564562992223 4.421018397009686 4.724452682902362 0.7158331323425442 0.2962190784221967 0.018318648604566 0.1234363306283571 0.033448252195247 0.0008963249378436 0.0003308073216795 +Regulation of endocytosis 14 57 2.6708470167476683 0.0075660120831855 10.009708737864075 47.5 0.2037917795721605 0.7044250618242573 4.669140886094089 7.163655572753937 0.7141975042751962 0.2991283724992093 0.0297208493411626 0.005312366512423 0.0135143906382874 0.0628225886105483 0.010493091667212 +Biological adhesion 44 197 2.6661176731900347 0.0076732829421417 36.79854368932039 169.14320388349515 -0.0786074092810717 0.7268401382457587 13.443000770803348 22.05897605707452 0.7413278367584214 0.3123990966272218 0.020624757269044 0.0454335883134377 0.0023294196983007 2.784690634227204e-06 0.0006413972460951 +Ceramide metabolic process 6 18 2.6599257920302373 0.0078157869645871 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 9.509760184517996e-05 0.0026953565990113 1.853550564308527e-05 0.0004442369263605 0.0060616304531859 +Sterol homeostasis 5 12 2.6576105738344684 0.007869676973248 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.0002441057313443 0.0148056693212618 3.186588308775749e-05 0.0002861284437042 0.0021190704165708 +Dendrite development 19 57 2.649384301007411 0.00806385777063 12.155339805825244 48.28155339805825 -0.0894217575688645 0.6130565352201668 6.6969885734181425 6.461112164518463 0.8656051627589799 0.3172962108162195 0.3984947412710319 0.5651415516676129 0.2277834669513959 0.0536793115171034 0.0013762081581565 +Anion transport 19 77 2.6486900617889457 0.0080804399132456 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0800078606866898 0.0745079706834489 0.0466400616976335 7.696439903211845e-06 0.0002922195610233 +Glial cell development 7 21 2.6422745567758343 0.0082351268958418 5.114077669902913 20.08495145631068 0.342527471970151 0.5482793913252476 2.6656928412824445 3.2664916525364203 0.9072377099594536 0.3081373734674846 0.0016884498183028 0.0035835009476038 0.0033323714802154 0.0185767987624415 0.0032646848465101 +Regulation of cell activation 16 73 2.6407607997384366 0.0082720099179482 13.849514563106796 65.59223300970874 0.0117954500841862 0.6466994765328734 5.255295503804918 8.314435794837985 0.810235540435219 0.3149538466828337 0.0200889383978919 0.0394703529271656 0.0146719781110468 0.0051568566562077 0.0916746787558606 +Regulation of tube size 1 11 2.6399113320618763 0.0082927720644061 2.325242718446602 10.861650485436892 0.4663835105130179 0.4051459652205314 1.5156285149919448 1.9062455332877175 1.0707303124706984 0.2893702596977744 0.0517352073763297 0.0204019662414969 0.0718258186813318 0.3010844649684869 0.6517647575525387 +Regulation of endothelial cell migration 9 31 2.6236224386363904 0.0087000168574891 5.495145631067961 27.978155339805824 0.5955926179251096 0.4502618340992453 2.841693008322481 3.167187428757454 1.0132828172462562 0.3207559953771818 0.0514908809094408 0.090603000234403 0.0183908054706022 0.0036505360581009 0.0114575734656985 +Amyloid beta clearance 2 11 2.621223464642258 0.008761481089389 2.0509708737864076 9.781553398058252 0.4002973882884584 0.4992490702724125 1.5887419548660706 1.7210432359369072 0.9239665506826532 0.3028953012168623 0.0148267428903527 0.0055832614279084 0.0210734332562196 0.017764157863851 0.09905667817091 +Neuron projection organization 10 26 2.619342745174328 0.0088099381188755 6.37621359223301 22.95873786407767 0.1300948006112363 0.595353189317293 4.79246143792415 2.5705098204655825 0.8930737213838517 0.3150112992576556 0.1110104387552961 0.046072228335376 0.1502138999638582 0.2440224888764268 0.0005243166168262 +Intracellular lipid transport 3 13 2.612229683146147 0.0089953797730508 3.2475728155339807 12.529126213592232 1.0333463606041455 0.2805251274605093 1.854375285913986 2.478377603832177 1.0146678848168829 0.2521579143644115 0.000139572011172 0.0112943240362007 0.0002865257018003 0.0081443152876 0.0747991773170861 +Lysosomal protein catabolic process 5 8 2.605825871872292 0.0091653042697812 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 1.1453789936630002e-05 1.4886062532767006e-06 6.354309454090493e-07 2.898375171077518e-06 0.0001461959825676 +Protein catabolic process in the vacuole 5 8 2.605825871872292 0.0091653042697812 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 1.7911542241865245e-05 2.3399875141854645e-06 1.132066507822963e-06 5.807781500787184e-06 0.0002808101441202 +T cell proliferation 11 25 2.602956419400238 0.0092423701409465 6.194174757281553 24.145631067961165 0.2896787294882859 0.6336134652888596 2.9709213778788497 2.668251916718813 0.7427908859202356 0.3020071268550194 0.1721884108424982 0.3651094145888684 0.0615174189559832 0.0248959026754067 0.0792490451083102 +Monovalent inorganic cation homeostasis 7 32 2.5987737459847864 0.0093557415408829 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0029013741513519 0.0496758524768897 0.000727293637541 0.0003859483694973 0.0087269486670011 +Associative learning 4 14 2.597774423141608 0.0093830111447434 3.2985436893203883 11.640776699029129 0.5833637693792252 0.3608696253992166 1.7586672512213413 1.9907766398439397 1.1416749351319833 0.2853176800833586 0.0002197647970036 0.0007667347448651 0.0004487726521249 0.0019200914773881 0.0083426651664859 +Tissue migration 11 57 2.5967087628599965 0.0094121690725514 9.67233009708738 53.092233009708735 0.2454422718783929 0.6331655573265219 5.302217104300144 5.995243896840201 0.808750167174679 0.3259792144953579 0.1971899829035669 0.2351834123815276 0.1131108154374408 0.0169678003561025 0.1289615277198751 +Cellular transition metal ion homeostasis 4 23 2.5955335386609604 0.0094444185125603 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0018956552183933 0.0402962873689797 0.0037316022130222 0.0209967954960545 0.0960095135742494 +Protein processing 12 55 2.5942710899200025 0.009479171258087 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.0009197317424528 0.0046881619119119 0.0004192854247962 0.0021288742160214 0.0077821963916086 +Antigen processing and presentation 5 27 2.5922419655627587 0.0095352681017379 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 0.0784025564630051 0.0316917589218704 0.0023109570743477 0.0025564989720558 0.0579649623036089 +Negative regulation of developmental process 22 110 2.590495771361913 0.0095837798996174 22.606796116504853 101.0631067961165 -0.1690080981071963 0.631864255638976 9.924264293838888 11.641526693087815 0.7921494883239464 0.3166468220789081 0.159571867536637 0.0219576714620816 0.152518192746982 0.0271844174869631 0.1089085622675603 +Regulation of epithelial cell migration 9 44 2.5879652961185733 0.0096544706827204 7.686893203883495 41.150485436893206 0.4683916151372655 0.5421818797250589 4.038230298045284 4.831799475569947 0.8737130528383311 0.3302003727650362 0.1108254421345311 0.1552273103013288 0.0518445335032981 0.0238956984566447 0.0896329544734611 +Transforming growth factor beta receptor signaling pathway 7 25 2.586303510342388 0.0097011464516851 6.740291262135922 24.87864077669903 -0.0956469866681699 0.6387114391471552 3.777556089888507 3.581889464108928 0.7561955554325939 0.2952697884954297 0.0699466130475088 0.4392448907866976 0.1074078448971524 0.320204448874428 0.1170738220129551 +Negative regulation of proteolysis 22 70 2.57587729217482 0.0099986122793727 13.856796116504857 64.19174757281553 0.1536213676829086 0.6668102754358496 6.420263538974692 5.397287151567414 0.8488834550270293 0.3356070904310471 0.0104757431323683 0.0455091327223478 0.0052712335982414 0.0066279543109287 3.912191558738082e-06 +Learning 4 22 2.573543420924374 0.0100663014945148 4.589805825242719 18.93446601941747 0.4051379104506336 0.500788863717711 2.588096905713564 2.8673042134954594 0.95936751956091 0.3128033021759736 0.0022385530869718 0.0044455523824174 0.0043894701524644 0.0249977551762954 0.1130329164300312 +Adult locomotory behavior 5 15 2.570312385777674 0.0101606846258226 3.95873786407767 14.822815533980584 0.7389907423501648 0.3383620981823156 1.833016072372531 1.4878680371825237 1.1254592435779416 0.2897204029443448 0.0002985134768044 0.0163255968864409 0.0006071735045487 0.0003819251815083 0.0028781147210985 +Antigen processing and presentation of peptide antigen 4 14 2.558157423770108 0.010522844373292 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 0.0310394603318191 0.0119629297909749 0.0003222994847708 0.0013008093576653 0.0233089974379561 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 12 31 2.556526235131407 0.0105723098457191 7.216019417475728 27.59223300970874 -0.0519383977494633 0.6701209774741869 3.707043372113383 4.2275951832081935 0.7338177625451779 0.2919617735055492 0.0265537390997117 0.1484013327004848 0.0475904817832995 0.4420799398829806 0.0180042278108211 +Tissue remodeling 3 20 2.5564396117740555 0.0105749424555221 3.66504854368932 16.594660194174757 -0.4917359988774192 0.4230166580965113 2.199832682863623 2.6500175179981453 1.1675597985012025 0.3259718546789134 0.1163031464585152 0.0484634562358207 0.033549372412386 0.0989961492390201 0.2736111683812483 +Artery development 3 11 2.552666270589456 0.0106901871567721 3.04126213592233 9.516990291262136 -0.3354094123560088 0.4560597544976848 2.0481453507714487 2.380585444414497 1.0494832567265522 0.3117695977494945 0.0856229888655945 0.0348230103466341 0.1170412325774002 0.058507953184155 0.3353387448493903 +Regulation of mononuclear cell migration 8 19 2.548965636227008 0.010804294579426 4.548543689320389 16.800970873786408 -0.0451470857329185 0.6235913245378032 2.5976226650972936 2.65933034660148 0.8401157368959713 0.2924888202464074 0.005417471152029 0.0195557545343205 0.009062215893767 0.0219504556074559 0.0011303287485076 +Alcohol metabolic process 15 87 2.54112467111962 0.0110496511315567 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 0.0070350701998932 0.0825625608894291 0.0010092242778695 5.199381193653835e-05 0.0065479472247191 +Cellular monovalent inorganic cation homeostasis 6 29 2.5382212568929843 0.0111417519493435 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0014975426414666 0.0358926009784828 0.000316040607354 0.0006748300938215 0.0091218528537202 +Regulation of neurogenesis 22 64 2.535047436987069 0.0112432099759836 10.95873786407767 57.16747572815534 0.1854107959782945 0.7186584202849315 5.787561684481048 6.504935425520193 0.6629162769918895 0.3069356590994738 0.2506780770906274 0.2807980004527436 0.3477480618641206 0.077378152651945 0.0079775610678312 +Lipid homeostasis 6 26 2.5343121059033624 0.0112668331658136 7.665048543689321 25.939320388349515 0.8425417577103904 0.3366972259521467 2.992619034719237 3.7336969269092393 1.1648658675422845 0.295769208633365 0.0046071561194768 0.0623838765899965 0.0013015424048323 0.0040824974236727 0.0486758951877882 +Regulation of phagocytosis 5 18 2.526489951122994 0.0115208684272682 3.3179611650485437 14.968446601941748 0.3209190136413688 0.5915166201342027 2.2957046675959747 2.326811751466005 0.7840787087563237 0.2941325518261171 0.0476798475193373 0.1908924307699622 0.0008016777344491 0.0037658297098364 0.0171255123594616 +Vacuolar acidification 3 11 2.525073836751078 0.0115673982776862 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0092050279194046 0.0034296220851759 0.0006712136127385 0.0008110696558398 0.0098879726868235 +Glycosphingolipid metabolic process 5 7 2.519792392078292 0.0117424069315272 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.000139572011172 0.0112943240362007 1.5663759637134803e-05 0.0001271352979986 0.0046837779345005 +Response to peptide 16 103 2.5187146171232246 0.0117784078252598 20.094660194174757 96.66019417475728 0.1432899082124719 0.7803896401267801 7.902517150358895 10.059824351434456 0.600783122030622 0.2900989611756318 0.0288385244904318 0.0026032373893375 0.0618759984121705 0.04794782727989 0.0228693370403259 +Hindbrain development 6 37 2.5117847645318285 0.0120122327434888 7.339805825242719 34.116504854368934 0.1921690100317769 0.6481106824796808 3.277766816309847 3.612413793438534 0.7182274377646931 0.2944599401766753 0.0421826517474328 0.078908455169182 0.0664204872480981 0.0084996601315941 0.0170591920619043 +Glycolipid catabolic process 5 6 2.510628081098567 0.0120516594009938 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 1.9231390410922443e-06 2.3666612945957126e-05 6.154716163450247e-08 1.632317154479711e-07 9.354890231096924e-06 +Ceramide catabolic process 5 6 2.510628081098567 0.0120516594009938 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 1.9231390410922443e-06 0.0015075035399645 6.154716163450247e-08 1.632317154479711e-07 9.354890231096924e-06 +Neurotransmitter transport 7 29 2.5100264747593286 0.0120722110363269 6.665048543689321 26.191747572815533 0.4855466408473005 0.5442577786721134 3.0345009262529348 3.012857536994118 0.8354081034116676 0.3113132472759617 0.5744666830004967 0.4018208263035032 0.271650808247468 0.0417714012612471 0.0667498460495771 +Developmental growth involved in morphogenesis 19 49 2.50865473079505 0.0121191877538997 11.49271844660194 41.66990291262136 -0.1705469350388877 0.6810855451733954 6.310912523707861 5.126342304944846 0.7270845598829705 0.2954893086550318 0.3279874249330972 0.5097893650742695 0.4141001289613655 0.0247882554789765 0.0017103181111931 +Developmental maturation 9 45 2.505197387519849 0.0122383073359737 9.04126213592233 42.12378640776699 0.2951074102250363 0.6104336491102619 3.871823327934924 5.43913517834949 0.8662608425150371 0.3328054790113054 0.0338059555446494 0.0369955408328181 0.05977481033742 0.3043437605620292 0.196326492343595 +Regulation of leukocyte migration 6 29 2.5015360185722457 0.0123655863388807 6.080097087378641 26.6504854368932 0.4712165673240142 0.5560717407414059 2.980664549328318 3.842679935245632 0.8934424673809059 0.3310773445531978 0.0215059099610276 0.0496758524768897 0.0347449548593629 0.0326937613140359 0.0087269486670011 +Carbohydrate derivative catabolic process 10 34 2.495759034197252 0.0125687949919754 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 3.269631281044485e-07 1.8221118180050497e-05 1.5273829722447616e-07 0.0001033904386809 0.0035869542362916 +Positive regulation of chemotaxis 7 18 2.4943675476598437 0.0126181809711776 4.817961165048544 17.016990291262136 -0.0747669348721738 0.5950152021464032 2.720538160362209 2.4538858959203873 0.8730469970494442 0.3017299719942363 0.0081785542562459 0.2222355866483168 0.0135653143077038 0.0078507588763973 0.0030132274761459 +Positive regulation of endocytosis 2 22 2.493110854403048 0.0126629304832024 4.560679611650485 19.640776699029125 0.3893750024867851 0.549188937881148 2.507020729109805 3.151065065533248 0.827344309517849 0.2971633472740571 0.0139350874315737 0.0034245890280422 0.0228098510804851 0.0645029072929147 0.1837162306077457 +Immune effector process 18 77 2.493002660662137 0.0126667897073649 15.24757281553398 71.95145631067962 0.1132149302474773 0.7134571835986485 5.865968077599497 7.248540048217676 0.7436652301031837 0.3039621470392462 0.0154844979238941 0.0328601744796203 0.0029668670248792 0.0409018063049507 0.004806752934768 +Regulation of ph 5 25 2.492306969441211 0.0126916295929948 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0008211635363398 0.0267403422938185 0.0001480247582341 0.0015871230225135 0.012512209523234 +Regulation of cellular ph 5 25 2.492306969441211 0.0126916295929948 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.000654661543498 0.0239365913087713 0.0001111606586644 0.0011585880107859 0.0091015487948519 +Blood vessel endothelial cell migration 9 25 2.490729411749824 0.0127481166145897 4.536407766990291 22.449029126213592 0.7681724367497832 0.3963490094539818 2.4704338498615206 2.406468634828595 1.0319905271466427 0.3120666413936225 0.1110104387552961 0.2919842266274133 0.0312241665816077 0.0002886408637045 0.0005243166168262 +Membrane invagination 3 13 2.490378752868744 0.0127607027111573 3.6941747572815538 12.16019417475728 0.0473496567323534 0.6174394728479946 2.548303271138053 2.060626721793156 0.8509677037136445 0.3077347987860288 0.0038488891828583 0.1747599807978781 0.006477682080963 0.0146129998399771 0.1203149601397993 +Transcytosis 1 8 2.48668253389926 0.0128940403964787 2.6893203883495147 7.381067961165049 -0.0963525316297316 0.5283427390922439 1.9769503149641223 1.1774296611822574 0.947888091156137 0.3079267096508385 0.0055914837945719 0.0020655426456597 0.0080257871552124 0.0445602183527292 0.1467539296032722 +Chloride transport 5 12 2.4847845475249697 0.012962986328749 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.0023797484711094 0.0112943240362007 0.0040346592713098 0.0011317572349641 0.0046837779345005 +Cellular ion homeostasis 18 100 2.4832554146248675 0.0130187703594164 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0067046068681738 0.0442732258868589 7.10512316964538e-05 0.0028526794145662 0.0449663341622199 +Ph reduction 4 16 2.4758181741402803 0.0132931257497972 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0014713217280779 0.0082126449787597 0.0001488581135043 0.0005176459432172 0.010448798153629 +Leukocyte cell cell adhesion 8 41 2.4726699668344665 0.0134107926040996 9.580097087378642 40.13106796116505 -0.0072139744683013 0.6847937044272435 4.740436667270146 5.131031220303653 0.7212479184446298 0.2978705300168665 0.7301382580467801 0.5451422660923099 0.4641940615408458 0.0946318432858537 0.2478735109300371 +Cerebellar cortex development 3 14 2.4669542047806217 0.0136267783966195 3.2014563106796117 12.951456310679612 0.4913835354280507 0.4216383686135529 1.7737836843231067 1.855867843348426 1.0191189701346923 0.2901119129344551 0.0327496360061982 0.012648542478749 0.0459506122728715 0.0100334254948701 0.0888289826938022 +Regulation of cell cell adhesion 9 46 2.464062303962221 0.0137372230176784 10.83495145631068 47.220873786407765 -0.0080303092203977 0.6913778743619202 4.947976123233631 6.572393810594877 0.7304846165102299 0.2977646221448794 0.8113120257734056 0.6332097195283641 0.5928629968036208 0.1217461870525947 0.3969757598999201 +Leukocyte mediated cytotoxicity 8 14 2.460364454621858 0.0138795989313944 4.351941747572815 13.985436893203884 0.4021439577883799 0.5004679143122512 2.4135380942775657 1.8380502421368885 0.9762325275008988 0.3133102965191064 0.0538078303441176 1.0 0.0010365081920375 0.0050545837055134 0.0015279037069893 +Cell morphogenesis 68 195 2.455850509454571 0.0140551611569461 41.90533980582524 173.21601941747574 -0.3471749169097284 0.6276611695248706 17.338667450591522 19.98711807663455 0.7849466437132413 0.3108568553556995 0.2799023428644594 0.2136553884143175 0.0540260931422018 0.0012234773145319 0.0015149984714698 +Iron ion homeostasis 4 20 2.453662125861972 0.0141409778740366 4.468446601941747 17.140776699029125 1.0306963602610326 0.26770320823289 2.1032740346004313 1.762496954108992 1.1437451534606062 0.2692749918411525 0.0007626845241698 0.0257915242502586 0.0015290244076972 0.0078507588763973 0.0365963272398627 +Organic hydroxy compound transport 6 34 2.453009167322756 0.0141666728240119 7.145631067961165 30.32766990291262 0.3121985122058121 0.5028073494895335 3.2773354290298986 4.4061862301676955 1.0194405540894098 0.3270691777029814 0.0019079144025098 0.0019501496897305 0.0006865524030811 0.0172365301092223 0.281557453352205 +Regulation of nervous system process 5 13 2.4519220403957083 0.0142095443885015 2.6941747572815533 11.186893203883496 0.709685710886722 0.4267375683332639 1.6891041598029932 2.2483053074671338 0.9287991925104498 0.3050882814355576 0.0668350320040178 0.2260688267312995 0.0921147949975289 0.1335053000482259 0.0397377338982377 +Positive regulation of mononuclear cell migration 4 11 2.4516101639216297 0.0142218645535008 2.8762135922330097 9.45873786407767 0.0886382248774921 0.5417098390792167 1.6300328286079158 1.7054300369397768 0.9929662660604948 0.3187573347288022 0.0187491014912179 0.007105321595433 0.0265618978442646 0.0247234076565489 0.0012998754323988 +Neuron development 51 211 2.450039898843298 0.0142840385729217 34.62135922330097 181.34708737864077 0.2741713926873628 0.7656699386252992 12.599789260723686 22.778234719870852 0.7085731328386405 0.3174955318913259 0.0208275723007407 0.0162909719435397 0.032709765010668 2.8829119967282017e-06 7.69104740829116e-06 +Negative regulation of immune system process 9 47 2.445719021480794 0.0144563613551251 10.262135922330096 46.91019417475728 0.2444799455656694 0.6277319776406994 4.757132947946456 7.065174604728879 0.8023664740567815 0.321929768279026 0.1666621847406374 0.2080546526177427 0.0274663163708318 0.0259997606501871 0.043096046960213 +Cellular component morphogenesis 51 152 2.4432603197058373 0.0145552341161827 29.817961165048544 132.93446601941747 0.0314200755217484 0.7461931622021263 12.05361677657582 16.684335902896763 0.7312955885385684 0.3072439636957093 0.2046315675524531 0.2152611047027561 0.2007860100551404 0.0008233235440215 0.0004164733695568 +Negative regulation of supramolecular fiber organization 20 45 2.442802892636538 0.0145736944523029 14.344660194174756 48.067961165048544 -0.1428490286443108 0.6549567366680907 6.317846938085449 4.776077392654747 0.8655851975479791 0.3242880376888204 0.2767906566012015 0.4664619130311752 0.354745757728376 0.6035899060321062 0.2789346863358766 +Response to amyloid beta 4 9 2.437763691218879 0.0147784313066496 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0008190506217037 0.0001834080308804 0.0014058650888959 0.0021324559374895 0.0043704316922178 +Cellular response to amyloid beta 4 9 2.437763691218879 0.0147784313066496 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0008190506217037 0.0001834080308804 0.0014058650888959 0.0021324559374895 0.0043704316922178 +Apoptotic cell clearance 5 10 2.437041521267179 0.0148079789362369 1.4150485436893203 8.16747572815534 0.7343377868729896 0.4133364508748849 1.6160802235364573 1.40166698151907 0.89060803593971 0.2988103853625464 0.0113114865314974 0.0937235599037543 3.741089337723684e-05 5.807781500787184e-06 0.0002808101441202 +Lipoprotein metabolic process 4 21 2.432202539324229 0.0150073127498673 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.152104590180354 0.0650462755169659 0.0507760863542232 0.056666707333059 0.3998794800633873 +Bone remodeling 2 10 2.4320218026640728 0.0150148034697354 2.012135922330097 8.191747572815533 0.5468180618257266 0.3931395839581789 1.401229799996741 1.3580503781098845 1.0682234655932243 0.2933332619823408 0.0418308574920996 0.0163255968864409 0.0583817580096799 0.0734338910721259 0.1288473164062758 +Positive regulation of synaptic transmission 2 18 2.426190731847538 0.0152582489208212 4.813106796116505 17.475728155339805 0.4358203865992658 0.5836764637458288 2.251541663478826 2.30909834121491 0.7613404062503117 0.3040027846338212 0.0192581415930694 0.046072228335376 0.0312241665816077 0.2440224888764268 0.2548424225486203 +Regulation of t cell proliferation 5 18 2.4131887132917016 0.0158136294767656 4.548543689320389 17.20873786407767 0.3678090213411445 0.5562508690900512 2.4712075613347495 2.4125725220194325 0.8250230708720367 0.3041137280888924 0.4367975808521693 0.2919842266274133 0.1502138999638582 0.0279194128393474 0.0534436555525331 +Bone resorption 1 7 2.412075760752818 0.0158619851450019 1.8592233009708736 7.014563106796117 0.2083023295273233 0.4386245488984792 1.545298971494424 0.9242060635806713 1.1410360097988987 0.3142453330896848 0.0187491014912179 0.007105321595433 0.0265618978442646 0.1318172807011351 0.3640245481081547 +Intracellular sterol transport 2 9 2.407088442478892 0.0160802751114612 2.0558252427184467 8.070388349514563 0.0137684001556507 0.4375742254192777 1.5763082249183784 1.941472978156742 1.1294096262834266 0.2971146481185643 0.0008190506217037 0.0055832614279084 0.0014058650888959 0.017764157863851 0.09905667817091 +Production of molecular mediator involved in inflammatory response 4 14 2.4047768233689064 0.0161823449497231 2.966019417475728 12.354368932038836 0.1592972255887565 0.61319676623286 2.187522134059814 1.790117244032998 0.8048602914317851 0.3023896321949654 0.034496077063378 0.0133509861907553 0.0483495219963649 0.0016938518124182 0.0291816562890673 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 6 16 2.403642121222825 0.0162326559013497 3.70873786407767 13.225728155339803 0.1207945387582695 0.6056782907647003 2.351950514476632 2.015719343011274 0.8095159596863328 0.2961773927622835 0.0133377930203514 0.2597451867723493 0.0218582842409203 0.1865630132096767 0.0281223334511535 +Plasma lipoprotein particle clearance 2 12 2.4030541454263763 0.0162587798737545 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 0.1509425000049774 0.0937235599037543 0.0009244711113057 0.0120645849010356 0.0144964406909979 +Glycoside metabolic process 3 9 2.402365805886688 0.016289409979133 3.283980582524272 8.611650485436893 0.5062828222010527 0.3204164092287125 1.4990079825210394 0.6824144700308834 1.298018080705215 0.2868097664691992 0.0002205530010257 4.844157765872774e-05 0.0003823532959252 0.0003832983840783 0.0049531384619904 +Positive regulation of leukocyte proliferation 5 15 2.402287196411323 0.0162929112100016 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.080787090338714 0.0327224420542492 0.0191373699896123 0.0133513277547448 0.06212243803085 +Regulation of plasma lipoprotein particle levels 2 15 2.402203632549505 0.0162966338320986 3.0485436893203883 14.031553398058252 0.231208625789076 0.3303314046534408 1.822878555656895 1.834532430195746 1.3070593144112836 0.2560846117575656 0.2241232989350378 0.141543756104335 0.0033713986773027 0.0391216296567294 0.0619922366647863 +Regulation of chemotaxis 6 29 2.40075518161533 0.0163612786105702 6.492718446601942 26.155339805825243 -0.0174824940836626 0.6237203663336152 3.3301280462202696 3.729330821967613 0.837371285025588 0.3037004773473938 0.0299940149088271 0.3361355940595682 0.047891776654715 0.01576602880028 0.0193099294165308 +Regulation of lipase activity 2 11 2.3824938883085856 0.017195817419537 3.262135922330097 11.20873786407767 0.5080857493577803 0.3640362286084045 2.107366483573331 1.390020380944142 1.1722840995258883 0.3007278087276755 0.0041367574832764 0.0009649225463882 0.0069536692626337 0.0734338910721259 0.3092787829323835 +Long term synaptic potentiation 2 11 2.381389849826566 0.0172474480667308 3.012135922330097 9.730582524271844 0.4069972937780292 0.4936148854997918 1.5319726166057843 1.7661148877091215 0.9317897164603502 0.2968501206773379 0.005417471152029 0.0195557545343205 0.009062215893767 0.0918272438847456 0.1653068273939545 +Mucopolysaccharide metabolic process 3 9 2.375043338535464 0.0175468898187809 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0517352073763297 0.1988423464133734 0.0718258186813318 0.0236436874746125 0.174947649934789 +Astrocyte differentiation 4 13 2.3737722836349584 0.0176074056617414 3.094660194174758 11.42233009708738 0.0584209125016935 0.5547337588992057 2.207285076469246 1.943694412377063 0.913626470884625 0.299483644308788 0.0035736152074797 0.0008295914112261 0.0060217503205503 0.0133642522995781 0.0095095891823194 +Dendrite morphogenesis 11 35 2.370540331695901 0.0177621059214563 6.922330097087379 29.33495145631068 0.0392542367033255 0.6458754200465586 4.7683000988594975 4.1552916021158355 0.7624317858280742 0.2897540445961646 0.584880781427078 1.0 0.2825796829681516 0.0157092440877508 0.0149727100324235 +Response to catecholamine 1 19 2.368989596925181 0.017836755155256 4.424757281553398 16.033980582524272 -0.0573072004904338 0.665365911087625 2.929042503896358 2.574861798461494 0.7023933973941993 0.2807441570165693 0.0538078303441176 0.2027885470531376 0.0746250944081647 0.3101487242993257 0.6636495922239115 +Erk1 and erk2 cascade 9 43 2.3666897313440027 0.0179479721590942 9.063106796116504 36.96116504854369 -0.2053186707626123 0.619818933957631 4.867755813359736 5.241585638133293 0.7756762372917579 0.3004670512341539 0.3219998713843761 0.50487672715324 0.1629635375300463 0.0079890994274221 0.0863070248645144 +Regulation of cell development 27 100 2.3661465287085197 0.0179743288916907 19.339805825242717 85.6383495145631 -0.0597091301622999 0.7276601339235527 9.426057045159808 9.7312321331523 0.6074097499890261 0.2783469042327845 0.4195383893680741 0.4164875911711549 0.5425017189276895 0.1699804004843465 0.0253793979640972 +Ion homeostasis 20 120 2.3661200698046887 0.0179756135695361 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0054864132196334 0.022715641704772 9.330184704173864e-05 0.0031951015108501 0.0562778908927764 +Cellular response to peptide 10 75 2.363849450841711 0.0180861605861304 15.512135922330096 71.98543689320388 0.1339793674773638 0.7290046555586139 7.235453991765964 8.363395832893957 0.6604460800519434 0.2979149736137888 0.1043287170017885 0.0224017135129833 0.1697703883846022 0.170505864337211 0.1865054502436887 +Synapse organization 18 74 2.361986907216964 0.0181772841583767 15.138349514563108 65.40533980582525 -0.0195426896139076 0.6809714664793302 6.570586502332626 8.060949294302048 0.7450742452311702 0.3050655104564015 0.3038457513710392 0.3244854389831326 0.4118318336321745 0.1265014532679202 0.0118260538103287 +Neuron recognition 4 8 2.3575889247382618 0.0183940492006184 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.2048067767459769 0.1287528218161406 0.2414457297612108 0.0005176459432172 0.010448798153629 +Myeloid leukocyte differentiation 6 35 2.35645646517618 0.0184502301684277 6.978155339805825 29.5873786407767 0.2011011027578964 0.6062202255251892 3.5082438965963396 4.0029886798733605 0.8431092642014025 0.3149214169729679 0.0126558857772233 0.1027744496234552 0.0234884289208764 0.0188658439386598 0.0192440505768817 +Response to transforming growth factor beta 7 34 2.3547276142437794 0.0185362875714827 8.410194174757281 32.536407766990294 -0.094101059672419 0.6394779055878194 4.225924723432897 4.710671082480533 0.7756039910569711 0.2958728495226654 0.1249149493821624 0.5266103228678283 0.1847545446978684 0.5060878002482374 0.1190085718168102 +Low density lipoprotein particle clearance 2 11 2.354341979462984 0.0185555312453902 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 0.1226742139485862 0.0756950383436983 0.0004672463302539 0.0063676045893722 0.0063533232968262 +Positive regulation of cell projection organization 18 72 2.3514088408670726 0.0187024716725676 16.111650485436893 64.17961165048544 -0.1586970883128776 0.6547877415164793 8.489694506275146 8.165566576734744 0.7232357301008159 0.2944737374040439 0.5645793526399844 0.6829262542482903 0.3959437641279347 0.0569561152358087 0.0178256610000849 +Vasculature development 20 105 2.3502169619052 0.0187624710728588 20.354368932038835 95.0 -0.2304125656009934 0.6533759527787552 8.394731087929287 11.260378168820724 0.7092119435529696 0.3032836594411232 0.2201920308267425 0.3071955566163423 0.0937714978933065 0.0171649833758902 0.1106242746572803 +Developmental cell growth 17 51 2.34474010239207 0.0190403467167776 11.611650485436892 43.19174757281554 -0.1770860133769491 0.6801510245972117 6.170290562478592 5.452765385017726 0.7007707445642444 0.2930184693300224 0.3009550409404452 0.4872995681469994 0.382974773130459 0.0175538492099469 0.0060417167576556 +Positive regulation of leukocyte migration 4 17 2.344232716418336 0.0190662708011981 4.097087378640777 15.49757281553398 0.0425334182634543 0.6319024426123137 2.2673904555241178 2.3008006061290747 0.8386767808878971 0.3052449059936994 0.0517352073763297 0.0204019662414969 0.0718258186813318 0.0966974979109908 0.0210947346086547 +Regulation of cell junction assembly 6 37 2.338525042545301 0.0193600281388899 9.259708737864075 32.94660194174757 -0.3358679076618157 0.5702437255549974 5.326525298900453 4.3036519947638725 0.8636914149992402 0.3111741135209888 0.2344878525078567 0.4279811411777856 0.3043925460154114 0.0206003420306574 0.3127645641376552 +Endosomal transport 18 85 2.3375873235905167 0.0194086661689172 18.62621359223301 73.93932038834951 0.1186519085167339 0.644720288610979 8.11663114827185 10.15480695988343 0.8992829354823526 0.3430729564402452 0.2268186207836896 0.2607027479133809 0.3181120693401902 0.0106924396729033 0.0045512799862445 +Carbohydrate metabolic process 22 145 2.335862534607402 0.0194984071467201 34.21844660194175 139.29611650485438 -0.5656770110174321 0.5032146838847018 13.810993563752842 11.927763340900242 1.1407068088015644 0.3581886500202023 4.463469311921062e-05 0.0093989855243751 6.772005679712612e-05 4.097273664823517e-05 0.015128931947848 +Metencephalon development 4 31 2.3294787799087446 0.0198337158819723 6.62621359223301 29.15776699029126 0.1157743503724719 0.6486466015568407 3.0752839055946404 3.0316874829457876 0.742378949324794 0.2946028982412914 0.0171479808364698 0.0425713267043903 0.0279020879533615 0.0236138009368106 0.0156922549658499 +Regulation of receptor recycling 1 8 2.325047988563904 0.0200693943164642 1.6286407766990292 6.337378640776699 0.0966152980587005 0.4651501747732646 1.7475239340520727 0.8420161439831481 1.061782718242377 0.2922293153728452 0.0082254277129148 0.0030581061915538 0.0117676307173903 0.0635022977163126 0.0470360579614364 +Positive regulation of hydrolase activity 19 107 2.324089674988353 0.0201206883139144 21.04368932038835 93.82766990291262 0.096103089584701 0.7144275416775405 7.189733374789747 10.202888959228012 0.6950791100609718 0.3085758923258638 0.3145205065029295 0.2429011338340974 0.2557400662576203 0.0461752939402746 0.1269377739300853 +Positive regulation of t cell proliferation 4 9 2.3196794965496137 0.0203582218032005 2.7475728155339807 9.599514563106796 0.5532192709084727 0.4333591055805664 1.6218678348817797 1.3191273068698348 0.9842106594117432 0.3010582825504118 0.2552924739487913 0.1624541869963563 0.0483495219963649 0.0110758722051871 0.0291816562890673 +Regulation of blood circulation 5 29 2.3142389528403062 0.0206546183644975 6.468446601941747 25.968446601941743 0.2893551661274923 0.4907026879809681 2.9627910146791003 3.1161144766543267 1.01050030268827 0.311329637702479 0.0378800643725738 0.3619523256513019 0.0599224496562618 0.0237395007847449 0.2832000621273893 +Glycoside catabolic process 3 5 2.3121686457993142 0.0207683914196592 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 2.828730351654048e-05 6.108202829893653e-06 4.947049331965399e-05 2.2502069418558096e-05 0.0003337445501144 +Regulation of long term synaptic potentiation 2 7 2.306636060227266 0.0210751174988108 2.191747572815534 6.026699029126213 0.6105178624452509 0.3860292464291884 1.2788913032023987 1.4948993461258857 1.1199694698848182 0.3107967468650517 0.0009305834118446 0.0060718409625537 0.0015953295223005 0.0199432580741765 0.1093101132411038 +Response to hepatocyte growth factor 2 8 2.3056575069925747 0.0211297772438288 1.83252427184466 5.682038834951456 0.22147406836211 0.5067944222688716 1.3469168089334904 1.8521485079710065 1.0288209560233612 0.3181783420506056 0.0064177808396821 0.0023758658868836 0.009201700056446 0.0052676758380378 0.0005388274165263 +Regulation of inflammatory response 12 40 2.30520782856015 0.0211549366423047 7.866504854368932 35.21844660194175 0.2295827008417531 0.6281567589262068 3.713547020474819 5.919020641452837 0.77351812014651 0.3063504476591706 0.1231189673655243 0.1673171702489807 0.1822950070070434 0.0306380548251407 0.0313674339796274 +Lymphocyte migration 5 12 2.300746689461492 0.0214059533506636 2.587378640776699 10.70873786407767 0.1446908350758375 0.5727454259790064 1.7389417388728898 1.7550541051110882 0.8715704655582563 0.3032086956591277 0.2733967462722031 0.1747599807978781 0.3196260593385788 0.0691213376044611 0.010788368915323 +Digestion 2 13 2.3006580102688 0.0214109692778077 2.6092233009708736 12.58252427184466 0.3381234209976164 0.4686867807613236 2.030163888989284 1.6251916800745976 0.9856074720843446 0.2928277273344397 0.2367426782920286 0.1499686155438198 0.0412914524019695 0.0458410907711806 0.0747991773170861 +Regulation of systemic arterial blood pressure 1 8 2.29599013269754 0.0216764455674633 1.9514563106796117 7.480582524271845 0.6591644372092078 0.3227631999327531 1.1543807719023411 1.5318976272183211 1.1594175747176596 0.2663405748898474 0.0230572634873926 0.0087935329278829 0.0325598174288622 0.157217223036351 0.4165733999734724 +Positive regulation of cell activation 10 43 2.2956327954945825 0.0216968859690618 9.66504854368932 41.58980582524272 -0.0344461667002542 0.6127678592935748 3.990819774604169 3.7854079772897897 0.9017662407322792 0.3302397387818446 0.0389677700166111 0.1795690337818556 0.0189720267908611 0.0147982937621144 0.1442047742685271 +Inorganic anion transport 7 28 2.293191080082394 0.0218370064661064 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0185394878957648 0.0448936661684744 0.0300946598886555 0.0014147813856964 0.0060441570275233 +Endocrine process 1 7 2.290932258280997 0.0219673319226134 1.2548543689320388 4.796116504854369 0.5618420388608887 0.420743873234336 1.155653359589049 1.5445439412417563 1.012934098296112 0.2874992399751413 0.0277307016086551 0.0106429023881486 0.0390334649397651 0.1834336275650726 0.4668475505043769 +Regulation of lipid transport 4 17 2.289344464946236 0.0220593461055091 4.084951456310679 16.67718446601942 0.3665821344953645 0.5500608719110902 2.096012568417446 3.1783802180721676 0.8243482455883206 0.2999534514421824 0.0905446093895194 0.0369748680428621 0.0228098510804851 0.0174389793074279 0.1837162306077457 +Lysosomal lumen acidification 2 6 2.285021992681936 0.0223115382263083 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0034334205639732 0.0012601973854463 0.0001426699384292 0.0020533662966424 0.0141665154869097 +Negative regulation of hydrolase activity 18 70 2.2848065498112016 0.0223241734420478 13.71359223300971 61.55582524271845 -0.0365477234421551 0.6686475173700427 6.008126350326953 6.2538756952931465 0.8021313488618124 0.3189731412355006 0.0126975001433623 0.0096570635022048 0.0066308796499983 0.0031357287676385 0.0006568613724631 +Digestive system process 2 12 2.27950670878716 0.0226369616268979 2.3640776699029127 11.53883495145631 0.3658311834032546 0.4870903581227657 2.0273544083065516 1.5921368074181557 0.9303375732228962 0.2866214695259424 0.2112978307962688 0.1330370821365251 0.0325598174288622 0.0329460998536745 0.0504521665366165 +Regulation of axonogenesis 13 31 2.2766504825270344 0.0228071057006087 6.298543689320389 24.33009708737864 -0.0369493998932667 0.7042332477256763 3.680926674103965 3.330903692400873 0.6576030741176464 0.2748175369765668 0.5378536991562 1.0 0.6057434613809523 0.0798509231648122 0.0058601021721165 +Amyloid precursor protein metabolic process 6 25 2.2760808741290357 0.02284116957623 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0737029175928528 1.0 0.0166167011229059 0.1505670934775949 0.0167583931949217 +Golgi to vacuole transport 2 8 2.275285539613865 0.0228888063265277 2.1990291262135924 6.684466019417476 -0.1721194290132491 0.5176214279350251 1.5293881729690744 1.066912547853689 0.9858058434549826 0.3169991723772594 0.0092050279194046 0.0847528009868792 0.0131546828557762 0.0089509329804495 0.0544656750173612 +Regulation of receptor mediated endocytosis 5 27 2.274849075933877 0.0229149850818823 4.793689320388349 24.031553398058257 0.302771523245338 0.6139564689831747 2.578601069629366 3.990458828834646 0.7718297586481511 0.306515207758586 0.1216592602205618 0.0508992589190798 0.0359624367366125 0.2704282249323606 0.1512534834039285 +Artery morphogenesis 2 6 2.2688486867718 0.0232775290747955 1.8446601941747576 5.497572815533981 -0.1453756942735048 0.4458938580524781 1.3220114238993363 1.9969622396143276 1.0910949618937522 0.3050258624648908 0.0456983473100118 0.0179094063189584 0.0636449972198752 0.0824073873197279 0.3363841302805421 +Skin development 6 39 2.2680002515091875 0.0233291913470292 7.716019417475728 37.949029126213595 0.1149612151751039 0.5923879086259207 4.010839158692918 4.095916037178702 0.8486146174549073 0.3069540780596735 0.0925591216823525 0.4795806297081992 0.040634807083858 0.0428516896733301 0.0273830291532244 +Positive regulation of epithelial cell proliferation 10 23 2.262980602848733 0.0236368850355539 4.383495145631068 21.718446601941743 0.2792283144280766 0.6284008382423802 2.80144196876276 3.7362498090328704 0.6904087020214402 0.2819908547781544 1.0 1.0 1.0 0.0285890862939352 0.0063456243919498 +Cholesterol efflux 3 8 2.2621139626434914 0.0236903631543294 2.5485436893203883 7.621359223300971 0.5111997846274834 0.3340620166024763 1.4780178328121285 1.039197831548229 1.1947983633918562 0.2643278716774433 0.0013213978898495 0.0076498462283805 0.0001285559926841 0.0039153945652928 0.0402069493791732 +Sulfur compound catabolic process 2 9 2.261086926459836 0.0237538747808845 2.533980582524272 8.429611650485437 -0.0778200633561399 0.4079928985578651 1.493126868113743 1.2057293827100195 1.164541998643716 0.2909806285388812 0.0136086826932428 0.1026081339138497 0.001231210484404 0.0157252402213966 0.0892170338783466 +Negative regulation of neuron apoptotic process 9 29 2.260291713652677 0.0238031519274741 5.757281553398058 26.135922330097088 0.5817179538337637 0.4854643114827585 2.727835727399863 2.4377633537168184 0.9011837787919588 0.3153742372034477 0.1492756548556804 0.0637102717405072 0.1992060977406469 0.0543659249851089 0.0074770103502822 +Regulation of cellular response to growth factor stimulus 12 39 2.259706615026747 0.0238394654799811 8.58252427184466 34.092233009708735 -0.0280079791968073 0.708743254851605 4.725523080605279 5.242307157545806 0.6640460187580217 0.2879428696977954 0.0413110990754599 0.5474081709152836 0.0721607867404205 0.3526590578288316 0.0487264630744735 +Sterol transport 4 23 2.25769508645324 0.0239646757856186 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.0022385530869718 0.0044455523824174 0.0005246070390923 0.0249977551762954 0.2364098572110782 +Heterotypic cell cell adhesion 5 12 2.257439463324245 0.0239806281629262 3.283980582524272 9.87135922330097 -0.1157334657886514 0.491655693009559 2.2510915754754093 1.39536510762595 1.0517413970520408 0.3057914387152954 0.2112978307962688 1.0 0.0325598174288622 0.0006131602837479 0.002368909886278 +Metal ion homeostasis 16 89 2.254931120929615 0.0241376525455916 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.0629815602618123 0.13795486567134 0.0042379687174316 0.0278713229023745 0.0916746787558606 +Chaperone mediated autophagy 1 8 2.2517538463962667 0.0243378317988525 1.9951456310679612 7.677184466019417 0.1640312365213783 0.4319192752719011 1.747390767216852 1.0240618889403386 1.1129367798588556 0.3015487526292348 0.0048180551758565 0.0017760204843955 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Regulation of cell projection organization 54 135 2.251237046035192 0.0243705276917849 24.968446601941743 116.3883495145631 0.1438396928004151 0.7137836838737817 11.111590839524858 13.66252973043869 0.7745745022937258 0.3212717801361091 0.7057904896442682 0.8920949042483466 0.6373196186268695 0.02371015409292 0.0056810692739499 +Ceramide transport 1 5 2.249303332563777 0.0244932039489369 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0048180551758565 0.0017760204843955 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Smooth muscle cell migration 3 10 2.2476303045463464 0.0245997735231593 3.7305825242718447 10.385922330097088 -0.3189264558769314 0.4706229844860156 2.237746927414025 1.9306158466576009 1.0411294498318489 0.3050809049980993 0.0418308574920996 0.1788224008957527 0.0583817580096799 0.0159331781494728 0.0121842961258669 +Positive regulation of erk1 and erk2 cascade 4 19 2.247327343749683 0.0246191146072647 4.29126213592233 16.58252427184466 -0.1278800773081511 0.5315513689884632 2.473671332922706 2.654083762495622 0.9131516716025438 0.2897967566182475 0.1110104387552961 0.2919842266274133 0.1502138999638582 0.0279194128393474 0.1251747232498637 +Regulation of cell killing 6 9 2.2453885210236417 0.0247432016809725 2.844660194174758 8.366504854368932 0.4041102541319114 0.4507662844932221 1.5842506516490529 1.3031494402288128 1.0522249449787806 0.3118972087461248 0.2177365324780222 1.0 0.0030667784637357 0.0057743966142769 0.0004790727366591 +Regulation of glycoprotein metabolic process 1 10 2.2442105032002733 0.0248188605711394 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0215796251678188 1.0 0.0305060181117638 0.1486468007453543 0.3992856920588761 +Positive regulation of binding 15 55 2.2423086398125576 0.0249414317505205 11.820388349514564 51.97330097087379 -0.0367767487556686 0.6444735417234735 5.2912064662609914 4.441831793991704 0.7729739616321648 0.3071478065657121 0.1040288596486384 0.0305051812830626 0.1558849497402792 0.1248451541149027 0.0004136529378951 +Positive regulation of cell killing 4 7 2.241977489289535 0.0249628272143536 2.344660194174758 6.594660194174757 0.4156629456801037 0.4127481983530973 1.3626949423444794 0.9467730739010484 1.1172564974004802 0.3098028662961327 0.157867792113085 1.0 0.0010709052035729 0.0014975917181939 0.002864460747413 +Vitamin transport 4 9 2.2415647690911342 0.0249895150977157 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.1783105780413945 0.1114073342812727 0.0228441699597423 0.0002424536403162 0.0053032680205866 +Receptor recycling 1 9 2.2413658621114325 0.0250023859153549 1.83252427184466 7.075242718446602 0.2017018942761934 0.4536082228606722 1.6905248328776263 1.154000508707628 1.0635166063679875 0.2938337757297349 0.0187491014912179 0.007105321595433 0.0265618978442646 0.1318172807011351 0.1309583783231107 +Regulation of lysosomal lumen ph 2 8 2.238282345836565 0.0252026486350063 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0064177808396821 0.0023758658868836 0.0003823532959252 0.0052676758380378 0.0049531384619904 +Xenobiotic transport 3 5 2.23756435939905 0.025249477928992 1.693827160493827 4.08641975308642 0.9732407293076591 0.2870054952103567 1.1547374966527622 1.4159369001791104 1.1259148135419206 0.2680466782257013 0.1509425000049774 0.0937235599037543 0.179062604831997 0.0012358112224234 0.0144964406909979 +Macrophage activation 2 7 2.237412597656092 0.0252593859349796 2.2135922330097086 6.866504854368932 -0.063381422560026 0.4721182263981376 1.4457872208921387 1.8783757746913443 1.04840992449182 0.2953484668101589 0.0033107591961438 0.0140700862732742 0.0055856505984271 0.0608575356821196 0.2688137047180795 +Cellular response to inorganic substance 7 42 2.235608734097223 0.0253774119747169 8.021844660194175 38.55582524271845 0.3118217467450566 0.6862388564014436 3.7787099682845775 5.080353367472772 0.6826079048933258 0.3095344385107431 0.0727982024360905 0.1153703567090803 0.1115354306593847 0.3313167659050693 0.126277574241662 +Antigen processing and presentation of peptide antigen via mhc class i 3 12 2.235002505185133 0.0254171842774746 3.5533980582524274 10.33980582524272 0.9522781165124746 0.321717188118692 1.7458864571217907 1.7766194475253527 0.972074824811495 0.2764762653101907 0.1647372735136017 0.1026081339138497 0.001231210484404 0.0017956484300789 0.020271757680103 +Neuron projection arborization 1 7 2.2342864379113183 0.0254642321146323 2.1189320388349513 6.410194174757281 0.2997181931700579 0.5356389026564765 1.6063982583137093 1.2538070031432729 0.9306716986687408 0.3086593014216465 0.1226742139485862 1.0 0.1459927402947744 0.0569248849368824 0.1818418904091173 +Cellular iron ion homeostasis 3 16 2.233514433965719 0.0255150395560519 3.66504854368932 13.521844660194176 0.8677978780626455 0.311898632686956 1.8823249793116483 1.671290558583202 1.0630934740559084 0.2702936919112085 0.0038488891828583 0.1747599807978781 0.006477682080963 0.0146129998399771 0.0396063215160503 +Muscle cell migration 3 13 2.2302580299844057 0.025730317751176 4.245145631067961 12.262135922330096 -0.2586179539693797 0.4687277297546733 2.50641908492515 2.0548836692490595 1.0581449707808777 0.3025519655210263 0.0623838765901622 0.2183837422916212 0.0861587362261736 0.0332787643737564 0.0336187943157164 +Negative regulation of cell activation 4 22 2.2281419635359927 0.0258710497368148 4.334951456310679 18.611650485436893 0.0974424490606073 0.6207305027054438 2.8835727817994763 3.79507347923476 0.7612807728269433 0.2836603378224073 0.1325482656466103 0.0559003563721154 0.1779321056766125 0.0417227578986097 0.1795318198605321 +Chemokine production 3 11 2.226688524022843 0.0259680979372163 1.8810679611650485 8.337378640776699 0.9152793985046536 0.327029475914965 1.2820382835273771 1.4780796128991345 0.9350060766690576 0.2657366976150246 0.230458544012733 0.1457663642848915 0.27085351108605 0.0424141111811751 0.0682397501835214 +Regulation of lipoprotein particle clearance 0 7 2.2231081058908524 0.0262085111999486 2.3228155339805827 6.45873786407767 0.0612839530437151 0.5154407402051848 1.5089261387443322 0.8594118327525224 0.9809593633922752 0.3136211913232979 0.0785196824488724 0.0479914252810258 0.0938999510605359 0.2191369015278419 0.3934410105686676 +Positive regulation of protein binding 10 26 2.220843013600236 0.0263615960860212 5.099514563106796 23.00242718446602 0.3155864476850776 0.5869976520948652 2.6175842559823277 2.8459635752908654 0.8435085117004013 0.3185282020054304 0.1006292377029538 0.0414278249847813 0.1367168788611213 0.0774145056148102 0.0003102982974167 +Lipoprotein catabolic process 1 5 2.21781180915426 0.0265676665971308 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.0064177808396821 0.0023758658868836 0.009201700056446 0.0506052248933858 0.1641299211995837 +Negative regulation of transforming growth factor beta receptor signaling pathway 4 11 2.2166208707996886 0.0266490101467071 2.6237864077669903 9.436893203883496 0.1519174108024199 0.5986838967496457 1.9059735511489473 1.2784236570272849 0.7879840609948254 0.2911082215509047 0.0399461524927002 1.0 0.0558103535730672 0.2464598217650195 0.0396063215160503 +Smad protein signal transduction 2 9 2.2165152171900817 0.0266562368836436 2.9223300970873787 8.470873786407767 1.0610232243819884 0.2706100861951009 1.609675360071813 0.9712499271368484 0.9663464864325269 0.2495327076802485 0.0399461524927002 0.0155575631698287 0.0558103535730672 0.0691213376044611 0.1203149601397993 +Organic hydroxy compound metabolic process 18 115 2.215782643674739 0.0267063916921346 24.233009708737864 110.8883495145631 0.5334558429683288 0.4627633417898757 8.017219191403747 10.01417249072314 1.2419084217888356 0.3713800795527268 0.0087236425707 0.0515307452558763 0.0004942964618177 7.661817173985491e-05 0.0130596095901115 +Regulation of biological process involved in symbiotic interaction 3 10 2.213005988629598 0.0268972327776444 2.3179611650485437 8.444174757281553 0.3422289691572587 0.5292477508521571 1.7867820286507592 1.14242547654536 0.8689534085392282 0.2992860869727938 0.2048067767459769 0.1287528218161406 0.0305060181117638 0.0300655360870906 0.0451666412494461 +Muscle cell cellular homeostasis 1 7 2.212204964344038 0.0269525059974384 2.0800970873786406 5.550970873786408 -0.3898571923856794 0.4513538970211284 1.417947371327862 0.8948743086477996 1.0863214598084368 0.3248014320258359 0.0048180551758565 0.0619434524836269 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Astrocyte development 4 7 2.2115688836590035 0.0269964674094436 1.662621359223301 5.529126213592233 0.4384947546692366 0.3812983981533123 1.2148997810479618 1.4027110413850483 1.1577934925672642 0.2956958593053811 0.0003886260619154 8.597904339497348e-05 0.0006712136127385 0.0008110696558398 0.0001461959825676 +Positive regulation of cell cell adhesion 6 27 2.208853450242871 0.02718483588048 6.548543689320389 29.79126213592233 0.2392641305343646 0.6381877105722645 3.259798197270223 3.572429669961151 0.7925488926612984 0.3104905639319101 0.6422818944148221 0.4611241633653626 0.3476177217996948 0.190605615405245 0.4090321283117494 +Macromolecule depalmitoylation 1 5 2.203985573245678 0.0275253586934984 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0040983965897468 0.0015075035399645 0.0058956460302812 0.0333651833289618 0.113339965404402 +Positive regulation of neuron projection development 11 32 2.2034068957611197 0.0275660826061792 5.320388349514563 27.266990291262136 0.1818751734009192 0.6001217862699426 3.530624940508957 3.8010700677703793 0.7786093307846155 0.2947257126705323 0.5378536991562 0.3713777336871285 0.235253462083624 0.0080357783248366 0.0019650917814895 +Regulation of cation channel activity 5 20 2.2011976408466283 0.0277220352482605 4.62621359223301 17.271844660194176 0.0934351855766884 0.5741768920956958 2.366040531994021 2.503179239680337 0.8688244316006214 0.3010087737996335 0.1031978917613202 0.0425713267043903 0.1400650262765533 0.0808304233724746 0.1071972712501636 +Lymphocyte mediated immunity 10 32 2.199494800980756 0.0278427584107692 8.46116504854369 33.900485436893206 0.1249025253075231 0.6066761672404548 3.501171316061164 3.2683091078637587 0.9080275598841054 0.325794744424275 0.0617090507207543 0.4222664170554933 0.0046331843911543 0.0188658439386598 0.0028373750226809 +Positive regulation of cellular protein catabolic process 3 52 2.1977684638956907 0.0279656098417209 12.177184466019416 48.599514563106794 0.0986048771054814 0.7012668574123421 6.659555062176937 4.58811251642548 0.7551300345102775 0.3055887019758087 0.0742434205828518 0.1169722030673408 0.113622012200689 0.3368812136284692 0.2306589812452646 +Amyloid fibril formation 3 9 2.196580242138663 0.0280504385859572 2.7233009708737863 8.089805825242719 0.5011823985301114 0.4066260207600095 1.722535041056919 1.3984016400026793 1.0784339491013113 0.3045914344390437 0.0124366578275625 0.0046633751497463 0.0177148463510605 0.0920739634299925 0.0172333771485565 +Glycerophospholipid catabolic process 2 9 2.1960442202935537 0.0280887784388492 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 0.0072960555134274 0.0027067874988798 0.0004672463302539 0.0063676045893722 0.0401461367370898 +Anatomical structure maturation 7 33 2.190538435524761 0.0284852104803401 6.815533980582524 30.893203883495147 0.3841260505655395 0.5416451005267833 3.09006416754166 4.620895179443306 0.9281404590939007 0.3269797675509184 0.0657676989389297 0.0182301376254106 0.1013332506493168 0.3035960646874314 0.1919350788720046 +Regulation of cellular response to transforming growth factor beta stimulus 5 16 2.188926493704721 0.0286021830845757 3.917475728155339 14.519417475728156 0.0747268719946895 0.6467964042170758 2.5548327395508266 2.189363442196086 0.7242791632240214 0.2849042613587436 0.1325482656466103 1.0 0.1779321056766125 0.5717749293752659 0.0851294147130311 +Regulation of signaling receptor activity 4 17 2.18810535802271 0.0286619287196543 4.199029126213592 14.597087378640778 -0.3646825040948551 0.5679947102605626 2.3891337807775925 2.5376373198552735 0.8092022514504403 0.2996550402970793 0.3935168848661239 0.2597451867723493 0.4528388306838392 0.1865630132096767 0.1753897866922502 +Regulation of leukocyte mediated cytotoxicity 4 8 2.1864487314064416 0.0287827916745744 2.5825242718446604 7.334951456310679 0.4511695306521209 0.4227043221453989 1.4499700153890709 1.2995300672557608 1.082342679990832 0.3098039206468536 0.1783105780413945 1.0 0.0015953295223005 0.00251045639703 0.0008256536450065 +Regulation of low density lipoprotein particle clearance 0 6 2.1850268854934085 0.0288868753687372 1.9878640776699028 5.526699029126213 0.0065330278648292 0.5256138018417175 1.328313150648338 0.7483092766324649 0.9599736511850174 0.3132913959239118 0.0633191306420368 0.0385773062479974 0.0758460972151271 0.1795191310032965 0.3296279245345712 +Lipid export from cell 0 5 2.1845438073909604 0.0289223119098438 0.970873786407767 2.8932038834951457 0.2910367285044455 0.4715568938765356 0.9238617838836146 1.0231554215679783 1.2098563714199235 0.3249767428136129 0.100864684735291 0.0619434524836269 0.1203280145079081 0.2750191284248381 0.4779737602264646 +Retinal ganglion cell axon guidance 3 5 2.1837987974009314 0.028977036011254 1.7864077669902914 3.66504854368932 -0.1607353104177084 0.5187197508410184 1.1073495465263443 1.060976719624544 1.0342406483767157 0.3259242375135492 0.1154630790463651 1.0 0.1375212864755611 0.0003832983840783 0.0049531384619904 +Aminoglycan biosynthetic process 2 8 2.1807513842863218 0.0292018101719033 3.0800970873786406 8.300970873786408 0.6387272076133388 0.2830924102482349 1.486473637192798 1.7113836533227735 1.3163721030030058 0.2655273000426038 0.2910660683117588 0.1868885334554594 0.339526513295544 0.0824073873197279 0.3363841302805421 +Phosphatidylcholine metabolic process 3 17 2.18022519415493 0.0292407729473618 3.75 12.592233009708735 0.9144963280277142 0.2812959412325629 1.879404212556404 2.4412987678409657 1.1545250012369797 0.2602001877022786 0.0399461524927002 0.0155575631698287 0.006477682080963 0.0146129998399771 0.0396063215160503 +Cytokine production 22 104 2.173526552476968 0.0297407096040962 18.97087378640777 96.13106796116504 0.0824735848580317 0.7508975178485808 7.48909409104055 11.178920255675855 0.680456448776925 0.3062861740716413 0.5064701538255058 0.2194362352690881 0.1052003767791658 0.1099582306537392 0.0324186674721703 +Osteoclast differentiation 3 12 2.171554468674761 0.0298892844947695 3.3567961165048543 10.419902912621358 -0.2065192558639911 0.557799022178809 2.186982100064913 1.6118167974780178 0.8796946296005602 0.3082817729760667 0.0073202198372533 0.2145132052110039 0.0121710399777804 0.0311941867040692 0.03080273588529 +Receptor internalization 10 23 2.1715169642623047 0.0298921162126579 5.912621359223301 22.271844660194176 0.0248047641463725 0.6748418376152933 3.544055041641504 2.734867188544325 0.6865207311689637 0.2805729207550325 0.0880733344897457 0.0358926009784828 0.1202677732034906 0.1865630132096767 0.0756252939231378 +Sprouting angiogenesis 4 16 2.1707708713658085 0.0299484968559835 2.866504854368932 13.946601941747574 0.1929244500672679 0.5584907474721589 2.165292064758145 2.09531680918901 0.8400779431440976 0.2782785167230157 0.3984836434715033 1.0 0.4582375595260778 0.0174389793074279 0.1837162306077457 +Pathway restricted smad protein phosphorylation 3 5 2.168742491295389 0.0301022394925829 1.691358024691358 4.5283950617283955 0.0669227535264893 0.5160880565934749 1.1551492374179229 1.2322051464502883 0.9870309906555468 0.3052191137626875 0.1715513885376269 0.1070183553885475 0.2030300441679912 0.4340702418800846 0.0236194052560011 +Macrophage differentiation 1 8 2.1676382123139173 0.030186223973442 1.6286407766990292 6.334951456310679 0.3401646730548612 0.4969679958563032 1.468258031702074 1.6603432057108871 0.9413197774531912 0.3033822894414889 0.1509425000049774 0.0937235599037543 0.179062604831997 0.0846217526668656 0.2546657991273667 +Cytosolic transport 14 70 2.1670080826808005 0.0302342378210318 15.3252427184466 64.33980582524272 0.1744021984538085 0.6762754968826091 7.447619264441359 7.422157064915613 0.8339042857759891 0.3289347094763193 0.1340368260801179 0.1778097782829715 0.1971826376931648 0.0142430684063797 0.0090876182913912 +Single fertilization 3 24 2.1660902637259016 0.0303042900625667 6.407766990291262 24.01456310679612 -0.3454877921915565 0.5968153798149883 4.73355486031475 1.8033898913952204 0.7361498023377534 0.2866721679835817 0.3575967580900071 1.0 0.0981876870196897 0.3814690602891797 0.2686893480606078 +Positive regulation of immune system process 22 125 2.165412403765769 0.0303561169986816 24.063106796116504 111.55825242718448 0.0014586405879444 0.7484751661806336 8.418420513377251 11.253004123360045 0.6663856016863496 0.2941180973009932 0.0343715214711789 0.0372702999338896 0.0119292759593068 0.0809186053689307 0.0032215965131431 +N terminal protein amino acid acetylation 0 5 2.1650673907944755 0.0303825247815821 1.7621359223300972 5.29126213592233 0.468170205145664 0.4621753504993651 1.4369342030361782 1.0061082182443093 0.9803510996484076 0.3117526403347991 0.1154630790463651 0.0711332726649859 0.1375212864755611 0.3100425591757577 0.5276895149825147 +Regulation of amyloid fibril formation 1 6 2.164943012906094 0.0303920496804754 2.2888349514563107 5.662621359223301 0.5261836595996398 0.3490055624244857 1.4817896559260575 1.2503440001723864 1.197683561482515 0.297347360341851 0.0034334205639732 0.0012601973854463 0.0049445172385496 0.0282524409787331 0.0141665154869097 +Negative regulation of chemotaxis 2 6 2.164116243868098 0.0304554291430836 1.8033980582524272 5.155339805825243 -0.0632726487639227 0.4544165494926578 1.311890397237956 0.9952048289283428 1.0730906602614034 0.2945723505476881 0.1715513885376269 1.0 0.2030300441679912 0.017764157863851 0.09905667817091 +Organic acid transmembrane transport 9 35 2.160565372380483 0.030728928709079 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.1380746617495529 0.326192706464958 0.1849845964283991 2.3101227461284523e-05 0.0004595134276763 +Myeloid leukocyte activation 6 25 2.1592349764629546 0.030831941832832 4.716019417475728 20.271844660194176 0.1798033859540577 0.5943364469586639 2.7981331640053257 4.1435273532735195 0.8470668099682189 0.3042600455440743 0.036841621470745 0.0718661948949039 0.0583474155448629 0.0226197092716897 0.0716509178019204 +T cell mediated cytotoxicity 4 7 2.1534551522075622 0.031282925112527 2.3155339805825244 6.371359223300971 0.523676216262352 0.4362981633701682 1.467264629016786 1.0863026706760155 1.002848585470677 0.3105377797682886 0.157867792113085 1.0 0.0010709052035729 0.0014975917181939 0.002864460747413 +Natural killer cell mediated immunity 5 9 2.152310418199581 0.0313729138284621 3.0266990291262137 9.79611650485437 0.3581391067116419 0.5074304089326694 1.9300298746867943 1.587935236879548 0.9456543485669218 0.3100992296137194 0.2241232989350378 1.0 0.0033713986773027 0.0065049624434193 0.0033809375709235 +Golgi to lysosome transport 1 5 2.151175959035281 0.0314623138368728 1.6504854368932038 4.604368932038835 -0.1604261304839933 0.5036105221859368 1.18205627865361 0.6319029203780867 1.034869173369558 0.3241536231264675 0.0028240506634377 0.0479914252810258 0.004071454093033 0.0234889728544392 0.0823369674942117 +Motor neuron axon guidance 3 7 2.1504183492175457 0.0315221382028485 2.3907766990291264 5.361650485436893 -0.2110710241337478 0.4966649478755087 1.4598884046461125 1.264828625014118 0.9818182905966252 0.3026854184981101 0.1226742139485862 1.0 0.1459927402947744 0.0005013179159177 0.0063533232968262 +Response to copper ion 1 7 2.150123763240425 0.0315454264019514 2.1237864077669903 6.650485436893204 -0.2406927634580937 0.4658860369394658 1.241169677348988 1.3861922271332412 1.0686867810452498 0.3023504783512977 0.0124366578275625 0.0046633751497463 0.0177148463510605 0.0920739634299925 0.2730711037423907 +Neuron maturation 1 7 2.150024175775052 0.0315533025260617 1.6966019417475728 5.737864077669903 0.3884050692002241 0.3270287101850628 1.1310653568868725 1.188220216330287 1.2760249805885358 0.2674215567147113 0.0173977458976559 0.0065792573185243 0.0246740936940832 0.123579290468326 0.3460963812051635 +Regulation of synapse assembly 2 10 2.146664343948519 0.0318200133509165 2.5606796116504853 7.859223300970874 -0.0792788242373662 0.5395185567400329 1.7274785273339432 1.5932464806786577 0.9385185942947613 0.3087264731082229 0.0456983473100118 0.1868885334554594 0.0636449972198752 0.0824073873197279 0.3363841302805421 +Cerebellar purkinje cell layer development 1 7 2.145583727453962 0.0319062048556677 2.191747572815534 6.961165048543689 0.8392766864609098 0.2843914142715297 1.2383946131318218 1.2878998490964535 1.1730456034866912 0.2696789702944095 0.1369226886862704 0.0847528009868792 0.1626892876910785 0.0703212183088513 0.2179847922025966 +Nerve development 4 10 2.1452059545147844 0.0319363837398947 1.5679611650485437 7.463592233009709 0.9323166733630548 0.322181793723066 1.371606215406715 1.1303984643014222 0.9327393846140116 0.2711478939504144 0.3026090861579831 0.1948770046367652 0.3524722176470324 0.0918272438847456 0.0614446561434308 +Amyloid beta clearance by transcytosis 0 5 2.145169016868653 0.0319393358648194 1.7427184466019416 4.62378640776699 -0.1321590834087047 0.5524368465261686 1.3115692773435086 0.7450270295544367 0.8638475235902433 0.2867638222114301 0.0556262242335954 0.0338360956076009 0.0666860823201616 0.1589658376068851 0.295251642909297 +Regulation of natural killer cell mediated immunity 3 6 2.144471785678058 0.0319951037680521 1.9053398058252424 5.33252427184466 0.1935470825099924 0.4776968923010209 1.19191069217632 1.22419398365008 1.049644639210895 0.3147111439809284 0.1226742139485862 1.0 0.0004672463302539 0.0005013179159177 0.0007525839576665 +Cellular response to lipoprotein particle stimulus 3 5 2.142375531285243 0.0321632752566554 1.25 3.8470873786407767 0.4175347012534766 0.3798602361667617 1.1183053232979376 0.9442808236527792 1.193491171404314 0.2885743012451784 0.0072960555134274 0.0756950383436983 0.0104494791604543 0.0063676045893722 0.0063533232968262 +Positive regulation of leukocyte cell cell adhesion 5 22 2.1406827367492087 0.0322996315921977 5.334951456310679 23.490291262135923 0.1442253125598469 0.607384554128015 2.81197884018417 2.9922882941913733 0.815787778894601 0.2985106722773643 0.5637945515640705 0.3928429005031874 0.2607188184236454 0.2332800595093329 0.3700752646543036 +Chloride transmembrane transport 3 6 2.133345016977485 0.0328964338963979 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.1298272630870375 1.0 0.1543818096433915 0.0075942890928168 0.0079931710216612 +Neurotrophin signaling pathway 2 8 2.131818068029993 0.0330218057118489 2.575242718446602 7.002427184466019 -0.28448872562993 0.4069596024308462 1.5206247723778896 1.4523145009764389 1.1265258568879903 0.2927189797017976 0.1715513885376269 0.1070183553885475 0.2030300441679912 0.1075130907868997 0.09905667817091 +Cell activation 29 141 2.12793458859046 0.0333425073055608 25.703883495145632 129.35679611650485 0.0692955426080309 0.7387037397563144 8.997285699976919 13.941847930447135 0.6883852192819997 0.3033879823523219 0.0169379338920258 0.0305887336404821 0.0205665436763559 0.0079508910206418 0.0130144622234555 +Cell migration involved in sprouting angiogenesis 3 9 2.125931403353789 0.03350897163733 1.5024271844660195 7.502427184466019 0.6299354700552533 0.4033822961376643 1.5192914585292825 1.07599307575227 0.9565887314303816 0.280512597606792 0.2241232989350378 1.0 0.2636091346473535 0.0065049624434193 0.0619922366647863 +Glucose import 2 9 2.1254947442246093 0.0335453521587369 3.4563106796116503 11.364077669902912 0.3176045676169922 0.5089134846135845 1.8514056534885703 2.196305563870774 0.9183417404528994 0.3012736273802708 0.0517352073763297 0.0204019662414969 0.0718258186813318 0.0966974979109908 0.3768947236315802 +Neuropeptide signaling pathway 2 5 2.125462215009634 0.0335480637018079 1.0849514563106797 3.1189320388349513 -0.0985724577330871 0.419688363037091 0.853358156505566 0.8690642357540188 1.297775726458379 0.3194504309420363 0.0048180551758565 0.0017760204843955 0.0069232563631819 0.0034327477034809 0.0228394808772788 +Modified amino acid transport 2 8 2.124229172595756 0.0336509849546482 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 0.1509425000049774 1.0 0.179062604831997 0.0120645849010356 0.0708751155690715 +Oligosaccharide metabolic process 3 7 2.122877468424848 0.0337641209943933 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 0.0008190506217037 0.1070183553885475 6.684645425207902e-05 0.0021324559374895 0.0236194052560011 +Cytokine production involved in inflammatory response 3 7 2.1223415805580013 0.0338090641295778 1.6844660194174756 6.915048543689321 0.5526695518877155 0.4572127495678942 1.5208746385948606 1.410799796429201 0.9262620288568464 0.3010153054171438 0.0148267428903527 0.0055832614279084 0.0210734332562196 0.0021324559374895 0.0236194052560011 +Immune response regulating cell surface receptor signaling pathway 12 32 2.122233673074319 0.0338181201564702 6.776699029126213 27.74271844660194 0.136139815526792 0.6569804635275405 4.022224759534535 4.3512993694161155 0.7512753157901814 0.2976989793111175 0.6332915146137531 0.453019277017924 0.3368794793344129 0.5762260391825298 0.0355762548676044 +Negative regulation of peptidase activity 12 39 2.1203551420915563 0.0339761066488928 8.29368932038835 36.58252427184466 -0.063782348021029 0.6095822183297694 4.3448059583944065 3.473266199713329 0.8447550419032326 0.3073217557628559 0.0082628338093317 0.0121763996061447 0.0027125023591343 0.0100095940368711 0.0009019434467098 +Carboxylic acid transport 8 41 2.119894649558318 0.0340149307234458 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.5779664120324384 0.4047844567784328 0.2752945686830158 0.0010447422510194 0.013126082022681 +Regulation of lymphocyte activation 11 56 2.117588913329629 0.0342098979277822 11.79126213592233 53.939320388349515 -0.0403403309035048 0.6613939899714961 4.794831497208694 5.719894384613908 0.769375886055445 0.3104578263686236 0.0942252447599016 0.085328871162868 0.0572046838151064 0.0756354768381402 0.2349877123396113 +T cell migration 4 10 2.1168894610425064 0.0342692303207283 2.5485436893203883 8.281553398058252 -0.1453768056585392 0.5423431297888617 1.715172955567082 1.540189597004688 0.9083302383460908 0.3027193057589817 0.1850152793775121 0.1157751708195439 0.2186221342412543 0.123579290468326 0.0063685282240186 +Membrane protein ectodomain proteolysis 8 14 2.1148715670869143 0.0344408951163484 3.2815533980582523 9.42233009708738 0.914660566901433 0.3175120830558543 1.6482852268027584 1.2623319489295757 0.9882621955102872 0.2679281534911034 0.0261335387625208 1.0 0.0368247433715485 0.0065049624434193 1.1127809854848747e-05 +Entry of bacterium into host cell 1 5 2.113464170336115 0.0345610585839792 1.3106796116504855 3.8276699029126218 0.2836426884969484 0.4711320987549692 0.9682245408111568 0.8656954148140601 1.0435307337239907 0.3123167717473686 0.0556262242335954 0.0338360956076009 0.0019368511639724 0.0115035556388008 0.0423042030727838 +Negative regulation of cytokine production 5 28 2.111690323050754 0.0347130195771441 5.587378640776699 27.0995145631068 0.3493721415420291 0.6285719352614387 3.172184314104491 4.02869558466082 0.7014733327898341 0.3026625991309797 0.5916832122693607 0.4164957533300368 0.6604325757838254 0.1279740148747566 0.1619712320485228 +Regulation of stress activated protein kinase signaling cascade 14 33 2.1079497512825847 0.0350353361224988 6.951456310679611 27.381067961165048 0.2313650341297954 0.6911021636242265 4.675651952415842 3.759509731675893 0.7215171740138203 0.3097912587256555 0.6240779730689023 0.4447949641299413 0.6926473948093821 0.3313167659050693 0.0648047463329864 +Epithelial cell proliferation 13 50 2.107186775881821 0.0351013927607024 8.395631067961165 43.269417475728154 0.2446678735146439 0.6859066232639723 4.286044223662435 5.981990499848451 0.6158202975211522 0.2863197731416702 0.5379775959055815 1.0 0.3665622313845076 0.0191404051453634 0.0404894540725562 +Intestinal absorption 2 9 2.103147506629612 0.0354528772947539 1.7354368932038835 8.587378640776699 0.5171971357504386 0.4141116500991276 1.4895775622567284 1.230532256111229 1.0157231952918233 0.2848944302917708 0.1154630790463651 0.0711332726649859 0.009201700056446 0.0052676758380378 0.0049531384619904 +Positive regulation of peptidyl serine phosphorylation 3 16 2.100959204605519 0.0356445475289506 4.308252427184466 17.00728155339806 0.276809177091258 0.5551626253781762 2.6189432861901603 2.5308668050305125 0.890892480182846 0.3012201308032535 0.0760409900665791 0.0306743412959273 0.1043706933170995 0.1564032996109324 0.1361256245763561 +Negative regulation of neuron death 11 48 2.0992911602803144 0.0357912421925505 8.007281553398059 41.070388349514566 0.4631357965023841 0.5436738617035674 3.9292833147190622 4.174866644537295 0.8641260319009939 0.3280793744080287 0.2707406645415977 0.1250660932411784 0.3476177217996948 0.190605615405245 0.018715330705788 +Amyloid precursor protein catabolic process 5 20 2.099064834990303 0.0358111857832297 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.3026090861579831 1.0 0.0690620672163432 0.2920005997725598 0.0190396454378568 +Brain morphogenesis 4 7 2.096659845718284 0.036023697471248 1.6771844660194175 6.138349514563107 0.1357465703968834 0.5273456692143654 1.3970022812219307 1.177369618108687 0.8696578162757159 0.2754790806224603 1.0 1.0 1.0 0.123579290468326 0.0063685282240186 +Negative regulation of neuron differentiation 3 7 2.095233318781002 0.0361502567684828 2.233009708737864 7.461165048543689 -0.1495079421232735 0.5679179654614803 1.7828954496469387 1.4617938846186531 0.8813245470493868 0.3066608596075524 0.3083107652154563 0.1988423464133734 0.3588505448912167 0.6720977570778652 0.174947649934789 +Platelet derived growth factor receptor signaling pathway 2 12 2.093003487877279 0.0363488432020169 2.1480582524271843 8.762135922330097 0.1166335759993331 0.644523758102582 1.9396028811105843 1.875162983458992 0.6908623357609962 0.2665500176607754 0.2491592407033175 0.1583124314184509 0.2921659829416722 0.0530915597366878 0.2421884168027767 +Positive regulation of lipid transport 2 9 2.092964569640627 0.0363523174586046 2.1699029126213594 7.0 0.0691898390202085 0.5172890321450091 1.660584465564179 1.8341422163787937 0.9343638939756568 0.2944184844578439 0.0310394603318191 0.0119629297909749 0.0435975481844182 0.0494008625159685 0.229043322451679 +Antigen processing and presentation of exogenous antigen 2 9 2.092643863172461 0.036380957912582 2.0800970873786406 7.682038834951456 0.7846141280949802 0.3912377722563422 1.42818099743969 1.069601013737802 0.957994485343778 0.3040877622263243 0.0173977458976559 0.0065792573185243 0.0018000470176383 0.0222629680099487 0.1199524552735497 +Leukocyte chemotaxis 5 30 2.09213350907916 0.0364265743564427 7.004854368932039 27.12621359223301 -0.0186974105931124 0.6948953376593175 3.940698243800774 2.645493004324857 0.6892497455842508 0.2851334438258616 0.1189734911484879 0.3024216363859021 0.1605058634275269 0.0326937613140359 0.0642903416117007 +Modulation of excitatory postsynaptic potential 1 5 2.0910845319298077 0.036520487042573 0.8616504854368932 4.184466019417476 0.8716049128546732 0.3904030169730884 0.8964791942932838 0.8154761884284932 0.955782621454512 0.3079648786148587 0.1298272630870375 0.0802348466038066 0.1543818096433915 0.3433804941091314 0.1998160014011807 +Regulation of cellular protein catabolic process 17 93 2.090094221336735 0.036609336676862 23.58252427184466 87.84223300970874 -0.0681449057139343 0.6891362029796801 10.716582080688289 7.57274512974492 0.8376729010478907 0.3110964117712532 0.2354441564249506 0.2680094392952094 0.3288906109980145 0.5689337768146053 0.0234900161310324 +Chemical synaptic transmission postsynaptic 2 13 2.0896298385773227 0.0366510640002013 2.4733009708737863 11.111650485436892 0.5657463373755282 0.4860434502535432 1.819998340098205 2.2081403224579756 0.8629150008491288 0.311233189592999 0.2491592407033175 0.1583124314184509 0.2921659829416722 0.5797145893212095 0.2421884168027767 +Regulation of postsynaptic membrane potential 2 13 2.0896298385773227 0.0366510640002013 2.4733009708737863 11.111650485436892 0.5657463373755282 0.4860434502535432 1.819998340098205 2.2081403224579756 0.8629150008491288 0.311233189592999 0.2552924739487913 0.1624541869963563 0.299132167535026 0.5900138775011101 0.2554523730097116 +Extracellular matrix disassembly 1 8 2.089063346139714 0.0367020212902535 2.2063106796116503 7.216019417475728 0.1063496442815648 0.573569007700299 1.7949927605074891 1.549956366317142 0.8506235788930436 0.3075454496370982 0.191665926491972 0.1201219647894398 0.2263045436956677 0.1318172807011351 0.3640245481081547 +Positive regulation by host of viral genome replication 1 6 2.0880317969932283 0.0367949665108806 1.8131067961165048 5.378640776699029 -0.1407998235620824 0.5734887265794838 1.5013013960555932 0.7388853433180756 0.8096275064164447 0.2856753665412284 1.0 1.0 1.0 0.0115035556388008 0.0423042030727838 +Response to ph 2 6 2.086995248327597 0.0368885640719964 1.7621359223300972 5.140776699029126 0.3480088533355521 0.3739523760080299 1.2528504590681426 1.153124661134805 1.2011912824917792 0.2945428652003891 0.1509425000049774 0.0937235599037543 0.179062604831997 0.0846217526668656 0.0708751155690715 +Protein localization to plasma membrane 14 83 2.085349564436678 0.0370375814137846 17.50485436893204 74.02427184466019 0.04078352472809 0.7298603923114082 6.16421521774153 8.588736878541509 0.688616631852129 0.3019343547464078 0.2550593947356767 0.6563757710533937 0.3531297780939855 0.0064858714608728 0.0336265347831016 +Cell maturation 2 25 2.0847272084216546 0.0370940694272932 5.558252427184466 23.611650485436893 0.3784230404296081 0.5141541830151944 2.6030237932680045 3.55055857689134 0.9250478571653724 0.3120408106541015 0.1577943404098645 0.0677466229044455 0.2099579933724119 0.3575433799302857 0.6187452089549611 +Regulation of t cell mediated cytotoxicity 3 5 2.083737528055788 0.0371840486270367 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 1.0 1.0 0.009201700056446 0.0052676758380378 0.0049531384619904 +Positive regulation of t cell mediated cytotoxicity 3 5 2.083737528055788 0.0371840486270367 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 1.0 1.0 0.0080257871552124 0.0042908003473226 0.0037759888499611 +Axon extension 11 30 2.083338105588962 0.0372204156871627 8.419902912621358 26.31553398058253 -0.2940772740266518 0.6381718568224477 4.879210105407428 2.4320775920792217 0.7080747181668522 0.2962229180666797 0.4595087541947337 1.0 0.523802502209471 0.0361429003688962 0.0290363363180858 +Amino acid transport 7 25 2.082279148450332 0.0373169793767413 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 1.0 1.0 0.4945801471111566 0.0066294247629262 0.0184969351752434 +Amyloid precursor protein biosynthetic process 1 5 2.078540334645472 0.0376596199187133 1.529126213592233 4.050970873786408 0.5724883308647799 0.4003128139433519 1.0007891127244537 1.1319816926742772 1.117383900072293 0.3129811194531851 0.00227122160607 1.0 0.0032780640178306 0.0190953097419897 0.0680064706612652 +Positive regulation of protein containing complex disassembly 3 7 2.0771661307493425 0.0377862286833012 2.0970873786407767 6.87378640776699 0.0022674715742681 0.5596009875722476 1.7460889061250944 1.1054113292370142 0.8029182662871821 0.2637082482054652 1.0 1.0 1.0 0.123579290468326 0.0312662716526952 +Negative regulation of defense response 10 31 2.075856189813616 0.0379072536562985 6.924757281553398 32.34466019417476 0.3561607180123788 0.5888237141063734 3.4481835219839927 4.979340389024908 0.80507298525878 0.3146610297306706 0.6049593917930556 0.4279811411777856 0.0993402801012091 0.0582621706836755 0.021690291144078 +Viral process 26 150 2.0744830665191327 0.0380344698071999 33.351941747572816 134.23300970873785 -0.425096328430862 0.6165060125927894 14.7574210759245 10.769837315206866 0.7119897372973428 0.312063278943757 0.0342739461487873 0.0576683087237199 0.0088224210867491 1.0063820172041554e-06 3.1070714237766382e-06 +Extracellular matrix assembly 2 6 2.072661635237228 0.0382037805677111 1.5655339805825244 4.844660194174757 0.2441705053919552 0.5544481976271249 1.2436543616195848 1.393516760646209 0.914170317979426 0.3133445413688597 1.0 1.0 1.0 0.1154739846724814 0.1093101132411038 +Positive regulation of mapk cascade 17 53 2.072413909162287 0.0382268573230004 10.529126213592232 45.83495145631068 -0.1934904160278876 0.6167608389842509 5.511385057852045 7.00568020214532 0.7988580356266328 0.3026624883715406 0.5128624207454988 0.6476405998709945 0.6141474242557738 0.1424065731717833 0.088777811155892 +Neurotransmitter secretion 5 21 2.072087833154233 0.0382572507793375 4.878640776699029 19.800970873786408 0.4739837619437216 0.5379742436571602 2.5178643472114657 2.5013004441236206 0.8040908235944773 0.3018218439933647 0.4897916341221495 0.3328373805982222 0.1920773275443584 0.3239829527385787 0.2097414112479707 +Aorta development 1 8 2.069840937755551 0.038467242334383 2.308252427184466 6.759708737864078 -0.0774176458664225 0.5304235266925468 1.8287429643020912 1.3840379619847545 0.941147128750552 0.3090353654428162 0.2674108336121077 0.1706778675257841 0.3128615540599918 0.2373655405257045 0.5591798689697555 +Regulation of nitric oxide synthase activity 1 6 2.069408180062776 0.0385077995511158 1.8980582524271843 6.400485436893204 0.8861714382596724 0.3064882013314778 1.014121704509923 0.9815283096291466 0.998778670456744 0.2492245557560045 0.1439609493286736 0.0892490045576324 0.0146091852998709 0.0773660358903978 0.236286730772413 +Regulation of anion transport 3 12 2.06661529756121 0.0387704181886725 3.657766990291262 11.50242718446602 0.7713855446015195 0.3761489496061844 2.0089273726107977 1.6987985280405251 0.9512307489218268 0.2850669663772418 0.2367426782920286 0.1499686155438198 0.0412914524019695 0.0458410907711806 0.0747991773170861 +Synapse assembly 4 20 2.065756556380131 0.0388514720735906 5.468446601941747 17.45873786407767 -0.3282763699124831 0.545572046602979 2.899861817023056 3.166227481604147 0.8429479411025542 0.2967774114004993 0.1325482656466103 0.3194831905047319 0.1779321056766125 0.1230506766835602 0.1795318198605321 +Neuron projection extension 14 40 2.0657191298096453 0.0388550079214664 9.898058252427184 34.12378640776699 -0.2408138783228371 0.6600334898859842 5.6477760995274116 3.7741735072882143 0.7158066122250335 0.2937117122355815 0.5814377020761121 1.0 0.6501318995178187 0.0451447821452261 0.0140264445175318 +Regulation of leukocyte chemotaxis 3 18 2.062330387030349 0.0391762918920544 4.288834951456311 15.735436893203884 0.121603520762296 0.6602233173792045 2.8123464966854943 2.274896040172022 0.7256331739166136 0.2891116210268169 0.0380950107843236 0.1706778675257841 0.0532804729840314 0.0649283885443843 0.0359117122080593 +Negative regulation of axonogenesis 3 8 2.0603910224535857 0.0393611744570441 1.4951456310679612 5.604368932038835 0.5111440741336667 0.4854399038461674 1.2969253139844743 1.1453919241926127 0.8397552514706781 0.2885954943863668 1.0 1.0 1.0 0.1658780833937837 0.0560616912320164 +Regulation of phosphatidylcholine metabolic process 1 5 2.05912395536329 0.0394823655449396 0.9490291262135924 4.286407766990291 0.730276510561534 0.3173678250634967 0.980303117936059 0.6650131093954683 1.1036579149092869 0.2546213828284323 0.0633191306420368 0.0385773062479974 0.0025659780541994 0.0150927838189798 0.0546176715347421 +Transepithelial transport 3 6 2.058371238607993 0.039554510466234 1.6553398058252426 4.774271844660194 0.6732735902855568 0.3468688130957016 1.1752486335033188 1.0771313051019258 1.1029852758785914 0.2818815040837556 0.1298272630870375 0.0802348466038066 0.1543818096433915 0.0075942890928168 0.0079931710216612 +Protein kinase a signaling 1 9 2.055997803757033 0.0397827278969389 2.266990291262136 7.293689320388349 -0.081456555052811 0.491906957237044 1.475225067542489 1.0944072211083502 0.9560488685138026 0.2840804811951539 0.1439609493286736 0.0892490045576324 0.1709159600444602 0.0773660358903978 0.236286730772413 +Neuron differentiation 62 240 2.05578180039865 0.0398035530423408 39.79611650485437 214.22815533980585 0.1406334423130582 0.8173940203730433 16.334405420842412 25.486649531945528 0.6060452870674871 0.2836433485410458 0.0664014679007062 0.0437353116982768 0.1026889515146641 0.0001741422696015 8.736696123399624e-05 +Mapk cascade 40 107 2.0525548867256216 0.0401157666809586 21.771844660194176 94.89320388349516 -0.1676833529148884 0.6923787829011968 9.873785214460888 12.932357717867903 0.6444104909931376 0.2891283107231593 0.8417142278800622 0.8647827925282126 0.756166906601086 0.1105053408547474 0.0202005596888372 +Regulation of platelet derived growth factor receptor signaling pathway 1 6 2.050135572729178 0.0403512029154682 1.3990147783251232 3.251231527093596 -0.1781565980011137 0.558471899847691 1.0187401737702908 1.2017786328420872 0.9944214655407514 0.3259840779299563 0.1226742139485862 0.0756950383436983 0.1459927402947744 0.0569248849368824 0.1818418904091173 +Regulation of transporter activity 8 47 2.0499677657333244 0.0403675764652169 10.191747572815531 43.932038834951456 0.1012053456490613 0.6855065791009368 4.523898766858667 5.186356515069559 0.7027420284840898 0.3005709748881068 0.0941635410202094 0.0272445176770422 0.1420367484612055 0.1070501746483492 0.1143469666957952 +Regulation of anatomical structure size 23 101 2.049484410348666 0.0404147707277953 21.26941747572815 92.63592233009707 -0.0858806462971143 0.7000515756128515 9.54614427580329 8.843760944555932 0.7224492645121989 0.3084213852497725 0.1937824555929196 0.400941761647145 0.2949951523128735 0.24606088218753 0.0904443226152658 +Positive regulation of cell adhesion 10 62 2.0434819466796905 0.0410047527165304 13.563106796116504 59.87864077669903 0.0297399042219727 0.7281141229464008 5.285389098319387 7.343832370136682 0.6806550249535446 0.2973683386009694 0.8335139158304876 0.6598101029121848 0.3585069752713783 0.2802091719368681 0.3685313607212144 +Ear development 7 24 2.042883481981229 0.041063973848229 5.366504854368932 23.73058252427185 0.0499252169512511 0.6477403607292388 3.3106395735414575 3.4826528013070557 0.7207599297712171 0.284814626074087 0.2525940451168345 0.1153703567090803 0.3260913714049449 0.3313167659050693 0.2240164147039343 +Regulation of amyloid beta clearance 1 6 2.0424881663677934 0.0411031320715573 1.1771844660194175 4.669902912621359 0.8976798268240034 0.3552262661555679 1.056723198112258 1.1917055536064145 0.9128228527254058 0.2874114892997187 0.0785196824488724 0.0479914252810258 0.0938999510605359 0.0234889728544392 0.0823369674942117 +Regulation of cholesterol metabolic process 2 7 2.041802292956436 0.0411711467280855 2.2936893203883497 7.036407766990291 0.4249970400619817 0.3648416816190511 1.505220359503101 1.431658251221006 1.1754439785533268 0.2764552996129673 0.0160900301160464 0.1114073342812727 0.0228441699597423 0.0199432580741765 0.1093101132411038 +Negative regulation of endocytosis 7 16 2.039444763734226 0.0414056586902027 3.0072815533980584 11.6747572815534 0.0267523710319225 0.5892853318615879 2.1559232897780234 2.5696215748968045 0.8334211374792047 0.2915117737472339 0.2674108336121077 0.1706778675257841 0.0532804729840314 0.2373655405257045 0.0021190704165708 +Detection of stimulus 3 14 2.033912115270605 0.0419604572185599 3.703883495145631 15.094660194174756 0.4988421371496737 0.4953505375843557 2.0878019439832904 2.71158439534448 0.904437685812264 0.3029606195069137 1.0 1.0 0.0247799010891251 0.0708068110484851 0.3802373669939536 +Cell activation involved in immune response 8 42 2.0335519221646177 0.0419967934732805 7.424757281553398 37.133495145631066 0.2013804059718359 0.6332706700932498 3.985004499798946 3.76547221312819 0.8111784803604789 0.3140247982994989 0.0213880457941844 0.0256886126869327 0.0387619599358554 0.0986819257429109 0.1023053488119434 +Regulation of b cell proliferation 1 7 2.0331778482313188 0.0420345582089334 1.7888349514563109 6.067961165048544 0.296043135362402 0.4569644069441661 1.2213996435499042 1.8129102062616271 1.0614819725849571 0.3010373616882123 0.0173977458976559 0.0065792573185243 0.0246740936940832 0.123579290468326 0.3460963812051635 +Negative regulation of growth 4 35 2.032851353676614 0.0420675430385844 5.817961165048544 30.390776699029125 0.1801984393176988 0.6389493459236367 3.663433547604644 3.7005919729330703 0.7775873943572781 0.3097525958014036 0.0941635410202094 0.1382881174102461 0.1420367484612055 0.2253668958128556 0.4731587719793236 +Regulation of response to wounding 3 17 2.032822199634232 0.0420704894546701 4.351941747572815 17.910194174757283 0.1916937563108336 0.6528179381928949 2.677653137862285 2.7171145748351506 0.6975187302586715 0.2828152410982211 0.4459930201446191 1.0 0.5094066821340305 0.0989961492390201 0.2736111683812483 +Regulation of monooxygenase activity 1 9 2.0324120679786484 0.0421119573981432 2.8932038834951457 9.66019417475728 0.7817888300341583 0.3389498053111844 1.538582258508953 1.1621322724229128 0.9599177691687591 0.2497120029370768 0.1982629499046588 0.1244478155008913 0.0285062952815799 0.1401767104122509 0.1423023069394473 +Response to wounding 24 83 2.020140356294831 0.0433688308400741 14.859223300970871 77.98300970873787 0.2907833523091244 0.6653892827271913 6.777288412904535 9.76879332264166 0.7686640367654125 0.3260596058790733 0.7133538777793195 0.780666375994921 0.3485010108776708 0.3253754267993964 0.4124432875902404 +Cellular response to calcium ion 1 13 2.016554345208925 0.0437420414976148 3.412621359223301 11.436893203883496 -0.1296326915368724 0.6297164730901523 2.33371987785202 1.6155789062088 0.7313618074007439 0.2818464085852687 0.0437484712182359 0.1828652209005429 0.0609936469852355 0.2646794233181401 0.6008853076934467 +Pinocytosis 1 8 2.0163269993634545 0.043765793446084 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 0.0092050279194046 0.0034296220851759 0.0131546828557762 0.0703212183088513 0.0544656750173612 +Response to nerve growth factor 6 15 2.0155484693820074 0.0438472128606415 2.9199029126213594 10.737864077669904 -0.0308315673557383 0.4841739597751167 1.7928910293158438 2.4592254090654397 1.0413664452810265 0.3101617236543262 0.0261335387625208 0.0100088432903632 0.0368247433715485 0.0391216296567294 0.0160305095638712 +Carbohydrate derivative transport 4 19 2.0116565962059094 0.0442561489373203 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0538078303441176 0.0212633176973237 0.0102417527095019 0.0254140783095469 0.0717558982580182 +Positive regulation of peptidase activity 8 47 2.004217005666494 0.0450468196843765 10.402912621359222 41.05582524271845 0.5528457293594794 0.5353148532065843 3.6877903061155113 4.060739093918417 0.9383664509883394 0.3555881721715914 0.0757014649291599 0.1185798153291669 0.1157235318918368 0.0286491714202897 0.1358560553513759 +Negative regulation of receptor mediated endocytosis 3 12 2.0031950057437475 0.045156361526387 2.4514563106796117 9.135922330097088 0.0418365941063717 0.5479583438408402 1.7736126303830697 1.981950317724577 0.882698777390703 0.2936432911803512 0.191665926491972 0.1201219647894398 0.0265618978442646 0.1318172807011351 0.0355737118947821 +Cerebral cortex development 10 30 2.0021019862362373 0.0452737639596767 6.279126213592233 27.216019417475728 0.0028465707635098 0.7167078279397867 2.9938855510536793 3.1957854041123483 0.6375968360481683 0.2766956278069873 0.4813146908943624 1.0 0.5468718822386345 0.0133275956191841 0.0154730541382535 +Regulation of monocyte chemotaxis 2 5 2.0020333663501195 0.0452811430733692 1.7985436893203883 4.563106796116505 0.2419118279045856 0.5315408384178865 1.2640272423687977 0.9943520397152368 0.9572879176135618 0.3175690600743351 0.0013389813605031 0.0338360956076009 0.0019368511639724 0.0004683577123997 0.0034775277607499 +T cell mediated immunity 7 11 2.001661884849902 0.0453211083411715 3.0145631067961167 10.46116504854369 0.1197287002677679 0.5708409161470714 1.5856705277946497 1.582963486610934 0.8689627261999604 0.297636200564505 0.3026090861579831 1.0 0.009062215893767 0.004165624514577 0.0050026695308212 +Regulation of vacuole organization 2 14 2.0012072515188564 0.0453700598276654 2.8567961165048543 11.82766990291262 0.1258946546155446 0.4588976974701806 2.33512175670257 2.002889031763913 1.0406614763927915 0.2804453828965037 0.3083107652154563 0.1988423464133734 0.0718258186813318 0.0966974979109908 0.174947649934789 +Regulation of phospholipase activity 1 9 2.000934105829482 0.0453994915192761 2.3033980582524274 8.655339805825243 0.4716760674233964 0.3608985608449799 1.8831620038679 1.0692732451911044 1.1444196149370027 0.2826906840950133 0.0230572634873926 0.0087935329278829 0.0325598174288622 0.157217223036351 0.4165733999734724 +Positive regulation of chemokine production 2 8 1.9982590888220504 0.0456885784041258 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 0.1715513885376269 0.1070183553885475 0.2030300441679912 0.1075130907868997 0.09905667817091 +Semaphorin plexin signaling pathway 2 9 1.9960808657510916 0.0459251214012557 1.5922330097087378 6.449029126213592 0.1285785339825718 0.5018629999830444 1.5339959443743525 1.3200559083210872 0.9351172255595104 0.2742371710353924 0.1850152793775121 0.1157751708195439 0.2186221342412543 0.0222629680099487 0.0312662716526952 +Ether metabolic process 3 9 1.99377262075552 0.0461769089637407 2.3009708737864076 8.116504854368932 0.6936598083237113 0.3993528168351505 1.8983127483146185 1.066260782267489 0.9725930071190376 0.2989456029254039 0.1369226886862704 1.0 0.1626892876910785 0.0703212183088513 0.0098879726868235 +Regulation of macrophage activation 1 6 1.992602116621968 0.0463050332388352 1.922330097087379 5.342233009708738 -0.2638468481870581 0.4667120676113176 1.321512228716618 1.3299619908714633 1.0155770170723395 0.2990962172269245 0.0102339970863349 0.0892490045576324 0.0146091852998709 0.0773660358903978 0.236286730772413 +Cellular response to fatty acid 0 6 1.9894539079892808 0.046651124492983 1.7184466019417477 5.315533980582524 0.014476298046786 0.6079916468648233 1.3522184270054574 0.8826545665189617 0.8415169274785789 0.3142217978300545 0.157867792113085 0.0981765691424607 0.1871299927573601 0.4053192290166058 0.6502314184365742 +Regulation of immune effector process 10 48 1.9888330966463328 0.0467196283464468 10.233009708737864 43.83252427184466 0.0746422295703071 0.6669022922564953 4.121819476399015 4.72533046431503 0.7694900850686928 0.3075467655920855 0.1074057483995667 0.1518063609135712 0.0124263893771024 0.0221788350136921 0.0424036001905225 +Myeloid leukocyte migration 6 27 1.987787433984524 0.0468352040798896 6.196601941747573 24.973300970873787 0.137730749742602 0.6535999513618568 3.1092858273424677 2.579185876047506 0.7446488106428547 0.2967340100846558 0.1110104387552961 0.2919842266274133 0.1502138999638582 0.007106566949162 0.0534436555525331 +Chemical homeostasis 34 194 1.9876033020364747 0.0468555808355559 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0001467176868909 0.0013790776941604 1.6168643403492482e-06 9.349499369126836e-05 0.0224018545530294 +Organic acid transport 10 53 1.9867700258736871 0.0469478876925599 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.3069800654544993 0.4923830768256354 0.1512218115452644 0.0005197950164847 0.0161311976150157 +Regulation of lymphocyte migration 3 8 1.98574623087479 0.047061508844872 2.0145631067961167 6.893203883495145 -0.036802973917011 0.5356237788613024 1.5071936093663014 1.6110216342446604 0.8950515723188286 0.2929579560704365 0.191665926491972 0.1201219647894398 0.2263045436956677 0.4746213136734084 0.0355737118947821 +Positive regulation of protein catabolic process 12 72 1.9835821548631325 0.0473024401872466 15.978155339805824 66.59708737864078 0.139767672471085 0.7371526177498576 7.64167219126692 6.702252284970635 0.6687206476686689 0.2986353115110999 0.1666621847406374 0.2080546526177427 0.2407998196724879 0.2482001592837529 0.1383885326260797 +Positive regulation of endothelial cell migration 8 22 1.982434771245448 0.0474306011557432 4.131067961165049 20.038834951456312 0.4292798614901122 0.501424383087746 2.512552144122521 2.5795022101891343 0.8904747448054084 0.2977037285288963 0.4367975808521693 0.2919842266274133 0.1502138999638582 0.0279194128393474 0.0534436555525331 +Skin epidermis development 2 13 1.979043558462036 0.0478111022747478 2.3932038834951457 11.968446601941748 0.2434049373997605 0.6509089917348749 2.4317384462669667 1.8982553345400648 0.6147637016740302 0.2519828053056315 0.0645963387267349 0.2222355866483168 0.0891217330395956 0.1279773017110395 0.2362988080518137 +Regulation of vesicle mediated transport 21 134 1.97844724563926 0.0478782743360926 24.555825242718445 117.33252427184466 0.2091879024365628 0.7679552913580993 8.949930305556254 13.223750714091672 0.6695514077553656 0.3058083256414907 0.053776789871427 0.079701490259028 0.0164025725558545 0.0338570551213788 0.0209398312168077 +Regulation of protein containing complex disassembly 21 40 1.977408336439836 0.0479954924241321 10.776699029126211 40.42718446601942 -0.1288073061501385 0.7193654094801857 5.876449689076856 3.7658453369588374 0.6232836184394875 0.278781264625845 1.0 1.0 1.0 0.4624037154787497 0.2363992701076228 +Inner ear receptor cell development 3 8 1.97660433026503 0.0480863723058901 2.138349514563106 7.223300970873787 0.0316029020279728 0.6151456906477899 1.7074324089806978 1.118529190586116 0.7448781022134199 0.2696215347935518 0.1715513885376269 0.1070183553885475 0.2030300441679912 0.1075130907868997 0.0236194052560011 +Regulation of t cell migration 3 6 1.9752367906407875 0.0482412826233775 1.5 4.483009708737864 -0.065072821388176 0.4977528624047557 1.1915967911258234 1.4303243809909685 1.0661805049889752 0.3090058258393087 0.1439609493286736 0.0892490045576324 0.1709159600444602 0.3751137360333714 0.0120515986398723 +Integrin mediated signaling pathway 3 19 1.9744529550753285 0.0483302617532204 6.402912621359223 16.310679611650485 -0.5379072072411986 0.4904146790285085 3.192495943864029 2.071672680098816 0.8524193588851617 0.3045400444515206 1.0 1.0 0.4741193373633443 0.2116843105930206 0.3914319483253241 +Defense response to gram positive bacterium 3 6 1.9715879502085476 0.0486566638709802 1.7427184466019416 4.492718446601942 0.047001436601032 0.591255631744899 1.20750902561483 0.9070625738948188 0.8367827300037257 0.3041101438807402 1.0 1.0 0.1709159600444602 0.0773660358903978 0.0120515986398723 +Lymphocyte activation 22 103 1.9701531234537248 0.0488208240989782 19.75242718446602 96.97815533980582 0.2587104991344978 0.7054244518764566 7.147670469313885 9.69771309720366 0.6795078753957892 0.3167596875043957 0.1679226689019872 0.2574546021469523 0.1406052467784101 0.0570108499407989 0.0164922163817648 +G protein coupled receptor signaling pathway 7 50 1.969474649708588 0.0488986108492577 8.648058252427184 44.101941747572816 -0.3770970612337289 0.4144255329514536 3.971368539216243 6.416702727999738 1.221530317440595 0.3246076536357387 0.0020481033364495 0.0006778874350895 0.0014025942191011 0.04347405983305 0.1865054502436887 +Basement membrane assembly 2 5 1.967735991511464 0.0490984223646204 1.6237864077669903 3.655339805825242 -0.1953809920001985 0.5654397565675079 1.170725952283126 1.3465690422339565 0.956711489493664 0.3193440867418824 1.0 1.0 1.0 0.0234889728544392 0.010684483318579 +Cellular copper ion homeostasis 0 5 1.966561978844681 0.0492337304154524 1.633495145631068 4.138349514563107 0.8027486766067657 0.3358654651123308 1.1881879887367894 1.18353805365164 1.0950331419070014 0.2903029711159642 0.100864684735291 0.0619434524836269 0.1203280145079081 0.2750191284248381 0.1297945989547683 +Copper ion homeostasis 0 5 1.966561978844681 0.0492337304154524 1.6771844660194175 4.669902912621359 0.4484316971142749 0.3058603694529516 1.2128614304476144 1.4202990900289796 1.3716690980071935 0.284002300922153 0.1226742139485862 0.0756950383436983 0.1459927402947744 0.3269170707962712 0.1818418904091173 +Aortic valve morphogenesis 1 5 1.966465339665704 0.0492448822598485 1.4368932038834952 3.087378640776699 0.1137914892546995 0.5168259349076642 1.0627853395276856 1.062208690998668 1.0995152634056735 0.3170510970821412 0.1369226886862704 1.0 0.1626892876910785 0.0703212183088513 0.2179847922025966 +Determination of adult lifespan 1 7 1.9641794550665608 0.0495092844970308 1.4684466019417477 6.878640776699029 0.9172678211727472 0.3356532972350567 1.327993783820954 0.8617154358126836 0.9778379941999832 0.290947936133699 1.0 1.0 1.0 0.0445602183527292 0.1467539296032722 +Bone morphogenesis 4 9 1.9639311171461515 0.0495380806693361 2.3737864077669903 7.519417475728155 0.7918915806069479 0.3290665752918499 1.3241931901591228 1.4011478132752644 1.0549507058478411 0.2731796281548322 0.3083107652154563 1.0 0.3588505448912167 0.0045948289685349 0.0664883963333954 +Regulation of steroid biosynthetic process 1 8 1.9632146149436465 0.0496212418640675 3.186893203883495 10.259708737864075 0.6168896095149775 0.3174156062343823 1.783561142158544 1.373475469974866 1.265753415239616 0.2847701277650337 0.2674108336121077 1.0 0.3128615540599918 0.2373655405257045 0.5591798689697555 +Cellular response to starvation 8 34 1.962737950450106 0.0496766310074499 6.796116504854369 31.22087378640777 -0.0779955424348341 0.7180828972780977 4.0020849500718585 3.884528836942906 0.6073955736911788 0.2732151802587211 0.2616652012504672 0.453019277017924 0.3368794793344129 0.07815743447109 0.1407831677812183 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4e6c6e6155c4b39d2288951fe104426731fc9769 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 6578, + "title": "Average number of proteins per term", + "value": 20.042870173304955 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56a39abb39d55e21159df4af889b87beef4fbe7b --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..28c64805fefda26e7203300b349ed4867669e5a7 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2582 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Taxis 0.7190558483391689 3.853560396277114 0.0001164125304804 0.5350410705616944 0.1325857773270528 76 P42892,P13591,Q6PCB8,P26583,Q92859,Q14118,P84095,P05067,Q9Y6N7,Q99538,P78310,Q8TEY7,Q13740,P33527,O94813,Q13641,P11047,P06756,P09429,P35613,Q15375,P29317,O14786 23 +Axon development 0.6763200735170597 3.8527075827460497 0.000116818868143 0.5362823393623419 0.1325857773270528 89 P42892,P13591,Q6PCB8,Q06481,O94898,Q9UJU6,Q92859,P84095,Q14118,A0MZ66,P05067,Q9Y6N7,P16949,P05556,Q66K74,Q8TEY7,Q9UIW2,Q04721,Q13740,P49768,P08238,P19022,Q14247,Q02750,P10586,O94813,Q8N0X7,O75955,P07900,P11047,Q6IBS0,Q13177,P78559,O75312,P43034,P35613,Q15375,P29317,Q9UQB8,O14786 40 +Circulatory system process 0.6846045107643899 3.831691400144651 0.0001272653103157 0.5670809352689348 0.1325857773270528 84 Q14126,P42892,Q02487,P33527,P42785,Q9UIQ6,Q07954,P08183,P30825,O94813,Q9HB40,Q96QD8,P10253,O75844,P02786,P78310,Q96PU5 17 +Inflammatory response 0.7192255797596806 3.8274557156100726 0.0001294746689812 0.5733279156383336 0.1325857773270528 75 Q9BQE5,Q06481,O95219,P01130,Q9BXW9,P26583,P05067,P02786,P05556,P42785,P22466,Q8IV08,P48960,P53634,P33527,P28070,P38571,Q08722,P04062,P09429,Q53EL6,Q9Y624,O60684,P29317 24 +Endocytosis 0.683739109815438 3.6411675409823223 0.0002714044376643 0.8322936429763059 0.1325857773270528 133 Q06481,P01130,Q9UJU6,O00560,P84095,P20645,Q5KU26,P62993,P05067,P11717,P50897,P02786,Q9NPF0,Q9UBG0,Q9H4M9,Q14108,Q99523,P05556,Q8TEY7,Q07954,Q08380,P49768,Q96ED9,O15260,O15118,Q08431,Q06787,P51790,Q96PU5,Q8WTV0,P42566,P06756,Q9UMY4,Q5VW38,Q8N3F8,Q9UNF0,P09496 37 +Entry into host 0.8329500153230533 3.622837227082646 0.0002913892005149 0.8529580673211496 0.1325857773270528 37 P05556,Q14108,P13591,O15118,P01130,P11279,Q8WTV0,Q9Y624,Q14118,Q92692,P35613,Q9BTY2,P29317,P02786,P78310,O14786,P08195,P06756 18 +Vacuolar transport 0.7440058069103793 3.6095470029111567 0.0003067321927596 0.8670781439113393 0.1325857773270528 57 Q14108,Q99523,Q07954,Q9UEU0,Q96ED9,O15118,P11279,P13473,P20645,P11717,Q96L92,P07602,Q9NUM4 13 +Behavior 0.6786945705756682 3.604900407689188 0.0003122726556064 0.8718367349469263 0.1325857773270528 78 P05556,Q8N122,P04062,Q92542,P22466,P01130,O15118,P54802,Q13641,P10253,P51790,P05067,P07686,P50897,O75844,Q99538,P17900 17 +Lysosomal transport 0.7517010198398851 3.552603593018517 0.000381438795497 0.9186978691765636 0.1325857773270528 50 Q14108,Q99523,Q07954,O15118,Q96ED9,P11279,P13473,P20645,P11717,Q96L92,P07602,Q9NUM4 12 +Cell morphogenesis involved in neuron differentiation 0.654797093248247 3.5282804125366027 0.0004182688156677 0.9361965386247766 0.1325857773270528 111 P42892,P13591,Q6PCB8,Q06481,P00492,Q9UJU6,Q92859,P84095,Q14118,A0MZ66,P05067,Q9Y6N7,P16949,P05556,Q66K74,Q8TEY7,Q9UIW2,Q04721,Q13740,P49768,P08238,P19022,Q14247,Q02750,O94813,Q8N0X7,O75955,Q13641,P07900,Q9Y4G8,P11047,Q6IBS0,O60678,Q13177,Q96PU5,Q14651,P78559,Q9NUM4,Q14444,P43034,P35613,Q15375,P29317,Q9UQB8,O14786 45 +Receptor mediated endocytosis 0.7145879311365714 3.461774176683396 0.0005366272174147 0.9707208993074726 0.1325857773270528 60 P05556,Q14108,P49768,Q07954,Q5VW38,P01130,Q9UJU6,O00560,Q8N3F8,Q06787,P20645,P05067,P11717,P50897,P02786,P42566,P09496,P06756 18 +Lipid localization 0.645214646858037 3.3703541973207973 0.0007507162159103 0.9928458723425848 0.1325857773270528 79 Q9NV96,Q9BQE5,P01130,P61916,P07602,Q14108,Q07954,P22466,P08183,O43772,P17900,Q9H2V7,O15260,P33527,O15118,P07686,Q99720,Q8WTV0,P06756,P04062,P35790 21 +Neuron projection guidance 0.8183431148974926 3.35355212802836 0.0007978138434259 0.9947530800329324 0.1325857773270528 32 P42892,P13591,Q6PCB8,O94813,Q92859,Q14118,P84095,P11047,P35613,Q15375,P05067,P29317,Q9Y6N7,Q13740,O14786 15 +Biological process involved in interaction with host 0.6870790174375369 3.3044040502847443 0.0009517854948299 0.9980960533588672 0.1325857773270528 62 Q9Y3E7,P13591,P01130,Q14118,Q9BTY2,P02786,P78310,P05556,Q14108,O15118,P11279,Q8WTV0,P06756,Q9Y624,Q92692,P35613,P29317,P08195,O14786 19 +Enzyme linked receptor protein signaling pathway 0.637049755289594 3.2964424575494213 0.0009791767086624 0.9984102522134588 0.1325857773270528 124 Q9UIQ6,Q06481,O94898,Q9H1E3,O00560,Q13526,Q92859,P67870,O00400,P11717,Q9Y6N7,Q99538,P62942,P16949,P05556,Q99523,P78536,Q07954,P49768,Q96B36,Q15043,Q6YHK3,P10586,Q8N0X7,Q9Y4G8,Q92896,P53999,O00459,Q53EL6,Q15375,P29317,Q9UQB8,O14786 33 +Cell cell adhesion 0.6250009281686744 3.2750216853647345 0.0010565386305232 0.9990447955192344 0.1325857773270528 111 Q14126,Q6PCB8,O60245,P30825,Q92859,Q9Y6N7,P02786,P78310,P05556,Q14517,Q14574,Q13740,P19022,Q02487,P10586,P04439,P10644,P06756,P09429,P07942,Q9P273,Q9Y624,Q92692,P35613,Q15375,Q08722,Q9UQB8 27 +Vascular process in circulatory system 0.7671337831551787 3.2453771537609706 0.0011729516071248 0.9995562300543857 0.1325857773270528 37 P42892,P33527,Q07954,P30825,P08183,O94813,Q9HB40,Q96QD8,P02786 9 +Steroid metabolic process 0.6624961426573889 3.241032833673421 0.0011909746547169 0.999605897752757 0.1325857773270528 68 P34913,Q9BQE5,Q13510,P04062,P22466,P01130,O15118,P61916,Q14739,Q9UBM7,P05067,Q16850,P38571,Q15392,Q99538,Q8WTV0 16 +Lytic vacuole organization 0.818978576955816 3.2381586268050504 0.0012030389913069 0.9996359991972632 0.1325857773270528 28 Q14108,O14773,P54802,O75503,P10253,P07686,P50897,Q9NUM4,P11117 9 +Vacuole organization 0.6776449403077898 3.2194086079793935 0.0012845530019245 0.9997872135335588 0.1325857773270528 61 Q14108,Q9Y3E7,O14773,P04062,O95219,P54802,O75503,P60520,Q9ULC3,Q9HC07,P10253,P07686,P50897,Q96ED9,Q9NUM4,P11117 16 +Phagocytosis 0.7112609834158943 3.2190734770734974 0.0012860552661679 0.9997893085910527 0.1325857773270528 44 P05556,Q06481,Q07954,P01130,Q08431,P09429,P84095,Q5KU26,P51790,Q8WTV0,P06756 11 +Positive regulation of response to external stimulus 0.6569085017272245 3.199217334989241 0.0013780124374946 0.9998850274437766 0.1325857773270528 68 O94992,P33527,P78536,O95219,P09429,P01130,P11279,O94813,Q53EL6,Q13641,P26583,Q92692,P05067,Q08722,Q99538,P53634,O14786 17 +Cell cell adhesion via plasma membrane adhesion molecules 0.8915505264637292 3.1942659100527147 0.0014018692602171 0.9999017470917122 0.1325857773270528 19 Q14126,P05556,P19022,Q02487,Q6PCB8,O60245,P10586,Q9P273,Q14517,Q92692,Q14574,Q9Y6N7,Q13740,P78310 14 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.6987804967491908 3.180009208020972 0.0014727037258674 0.9999383837848008 0.1325857773270528 48 P05556,Q6YHK3,P78536,Q9UIQ6,Q06481,Q07954,Q53EL6,O00560,Q13526,Q8N0X7,P67870,Q92859,Q92896,P53999,O00400,P62942 16 +Membrane lipid metabolic process 0.735556292608093 3.0969804141786033 0.0019550279042701 0.9999974329699808 0.1325857773270528 38 P04066,Q13510,Q8NCC3,P06280,P07686,P50897,P16278,P17900,P07602,P06865 10 +Anatomical structure homeostasis 0.7060254720943859 3.086467244976431 0.0020255026129347 0.9999983867634028 0.1325857773270528 42 P05556,O14773,Q9Y624,P13473,P11047,P10253,P51790,P38571,P02786,P78310 10 +Neuron death 0.6097202645246032 3.083214982412334 0.0020477716281246 0.9999986070024428 0.1325857773270528 79 Q9UMX5,Q9Y6K9,P48681,P05067,P50897,Q99538,P49768,P08238,Q96B36,Q92542,Q15392,Q99720,O95831,P05198,O75312,Q9NR28,P04062,Q15375,Q01105,Q13564,O14786 21 +Neuron apoptotic process 0.6792906265330925 3.071788229822083 0.0021278062463157 0.9999991780791933 0.1325857773270528 50 O75312,Q9NR28,Q99720,Q92542,P04062,P08238,Q15375,P48681,P05067,P50897,P49768,Q99538,Q96B36,Q01105,Q13564,O95831,O14786 17 +Locomotory behavior 0.7875313083817493 3.0707246141201487 0.0021354000336908 0.9999992182105882 0.1325857773270528 28 O15118,P54802,P10253,P51790,P05067,P07686,P50897 7 +Regulation of blood pressure 0.863794521352278 3.065703269622048 0.0021715871117502 0.9999993841317324 0.1325857773270528 19 P42892,Q9HB40,Q9UIQ6 3 +Cell morphogenesis involved in differentiation 0.623499441350667 3.0625646976351493 0.0021944903142956 0.9999994704401378 0.1325857773270528 144 P42892,P13591,Q6PCB8,Q06481,P00492,Q9UJU6,Q92859,P84095,Q14118,A0MZ66,P05067,Q9Y6N7,P16949,Q99828,P05556,Q66K74,Q8TEY7,Q9UIW2,Q14517,Q04721,Q13740,P49768,P08238,P19022,Q14247,Q02750,O94813,Q8N0X7,O75955,Q13641,P07900,Q9Y4G8,P11047,Q6IBS0,O60678,Q13177,Q96PU5,Q14651,P78559,Q9BYJ9,Q9NUM4,P06756,P07942,Q14444,P43034,P46108,P35613,Q15375,P29317,Q9UQB8,O14786 51 +Sphingolipid metabolic process 0.7802189176716112 3.0312821401518857 0.0024351758301908 0.9999998916741876 0.1325857773270528 28 Q13510,Q8NCC3,P06280,P07686,P50897,P16278,P17900,P07602,P06865 9 +Sterol metabolic process 0.703963843848338 3.0275714922494896 0.0024652739197075 0.9999999111746632 0.1325857773270528 41 P34913,Q9BQE5,P04062,O15118,P01130,P61916,Q14739,Q9UBM7,P05067,Q16850,P38571,Q15392,Q8WTV0 13 +Aminoglycan metabolic process 0.9104319190554528 2.996020065535786 0.0027352843422621 0.9999999850320254 0.1325857773270528 14 P04066,P15586,P54802,Q7LGA3,O43505,P07686,P16278,P06865 8 +Negative regulation of response to external stimulus 0.6700898892457768 2.986337400675528 0.002823409409407 0.9999999916303626 0.1325857773270528 48 Q6YHK3,P01889,P80303,Q9UMX5,P04062,O94898,P01130,P28070,O94813,O43657,Q9Y3Z3,Q9Y6N7,P04439,O14786,Q7Z739 15 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.9074425760548104 2.9832615433248795 0.0028519417093164 0.999999993066318 0.1325857773270528 14 P05556,Q14126,P19022,Q02487,Q6PCB8,O60245,Q9P273,Q14517,Q92692,Q14574,Q9Y6N7 11 +Cell recognition 0.7891119769504255 2.9790675642356983 0.0028912701762113 0.99999999465082 0.1325857773270528 26 Q6PCB8,Q08431,Q5KU26,P35613,P05067,Q9Y6N7,Q8WTV0,O14786 8 +Regulation of nervous system development 0.6156827637083082 2.9655414198781247 0.0030215065532894 0.9999999977346978 0.1325857773270528 72 Q06481,P01130,Q9UJU6,P26583,Q14118,A0MZ66,Q9Y6N7,P55209,Q9UIW2,P49768,P53634,Q12959,Q02750,O94813,Q8N0X7,Q13641,Q9Y4G8,Q6IBS0,O75312,Q14444,P43034,Q15375,Q15154,Q15382,Q9UQB8,O14786 26 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.592048942601685 2.962349044964717 0.0030530147173406 0.9999999981599073 0.1325857773270528 80 Q99523,P49768,P78536,Q07954,O94898,Q9H1E3,Q9Y4G8,P16949,Q15375,O00459,P11717,P29317,Q9Y6N7,Q99538,Q9UQB8,Q15043,O14786 17 +Response to growth factor 0.5879845479388339 2.9436353482514357 0.0032438194983173 0.9999999994775688 0.1325857773270528 112 Q06481,O00560,Q13526,Q92859,P05067,O00400,Q9Y6N7,Q99538,P62942,Q9H223,Q9H4M9,P05556,Q99523,P78536,P04792,Q04721,P08238,Q96B36,Q6YHK3,O95429,O94813,Q8N0X7,Q9Y4G8,Q92896,Q13177,O75312,Q9C0C9,Q53EL6,P29317,Q9UQB8,O14786 31 +Leukocyte proliferation 0.703070132131047 2.937141917499437 0.0033125247551628 0.9999999996680236 0.1325857773270528 39 P04062,Q92542,P22466,P30825,P09429,P02786,P04439,Q9NPF0,P10644 9 +Positive regulation of locomotion 0.5662692568608501 2.927870613849823 0.003412920381703 0.9999999998288684 0.1325857773270528 88 P05556,Q13685,P78536,P09429,P07942,Q08722,O94813,O00560,Q13641,Q9Y4G8,P05067,P29317,Q99538,Q8WTV0,O14786,P43121,P06756 17 +Cognition 0.6994270933700282 2.9143078406737204 0.0035647819386912 0.9999999999371978 0.1325857773270528 39 Q92542,P01130,Q13641,P05067,P50897,Q99538,P17900 7 +Cell chemotaxis 0.6861790655296439 2.913550153328397 0.0035734443103971 0.9999999999406884 0.1325857773270528 41 P33527,P78536,P04792,P09429,Q96JJ3,O94813,Q13641,P26583,P84095,P46108,O95747,P35613,P29317,Q99538,P78310,O14786 16 +Regulation of neuron projection development 0.56653211746379 2.879259568855681 0.0039861010671566 0.9999999999961114 0.1325857773270528 85 Q9NV96,O94898,Q9UJU6,Q12834,Q9Y6N7,Q9H4M9,Q14108,P49768,Q13308,Q9NQX7,P19022,P10586,O94813,Q8N0X7,Q9Y4G8,Q32P28,Q96PU5,Q9NUM4,Q14444,Q9P273,P43034,Q15375,Q9UQB8,O14786 24 +Biological process involved in symbiotic interaction 0.5594554242407976 2.8749218694097216 0.0040412748700202 0.9999999999972988 0.1325857773270528 87 Q9Y3E7,P13591,P01130,Q9H1E3,Q14118,Q9BTY2,P11717,P02786,P78310,Q14108,P05556,O15118,P11279,Q8WTV0,P06756,Q9Y624,P27105,Q92692,P35613,P29317,P08195,O14786 22 +Membrane lipid catabolic process 0.9349255335228494 2.866160286994415 0.0041548381906675 0.9999999999987242 0.1325857773270528 11 P04066,Q13510,P06280,P07686,P50897,P17900,P06865 7 +Organophosphate ester transport 0.744076111151569 2.8575887116594005 0.0042687329261199 0.9999999999993988 0.1325857773270528 29 Q14108,Q9NV96,P33527,P01130,P08183,P61916,O00400,Q08722,Q8WTV0 9 +Blood vessel morphogenesis 0.5639805075261797 2.856729463425794 0.0042803049181912 0.999999999999443 0.1325857773270528 85 P05556,P19022,Q13685,P42785,Q07954,P01130,Q08431,O94813,Q9Y4G8,P35613,P29317,Q9Y6N7,O14786,P43121,P06756 15 +Ameboidal type cell migration 0.5763378076034764 2.8551171991224917 0.0043020950076593 0.9999999999995176 0.1325857773270528 81 P05556,P19022,Q13685,P78536,P42785,Q06481,P09429,O95429,O94813,Q13641,P43034,P67870,P29317,Q9Y6N7,Q99538,Q8WTV0,O14786 17 +Endothelial cell migration 0.6896384264409633 2.8526377246640493 0.0043358019593779 0.999999999999614 0.1325857773270528 39 P05556,Q13685,P42785,P09429,O94813,P67870,P29317,Q9Y6N7,Q99538,Q8WTV0,O14786 11 +Receptor metabolic process 0.7003017773235444 2.8434906467750536 0.0044622319077634 0.9999999999998326 0.1325857773270528 37 P05556,P42892,P49768,Q07954,P01130,O00560,P02786,Q99538 8 +Viral life cycle 0.570818846257254 2.839218748331739 0.0045224142731008 0.9999999999998876 0.1325857773270528 105 Q9Y3E7,P13591,P01130,Q9H1E3,Q14118,P02786,P78310,Q14108,P05556,Q12899,O43719,O15118,P11279,Q06787,Q8WTV0,P06756,Q9Y624,P27105,Q92692,P35613,O60684,P29317,P08195,O14786 24 +Cell part morphogenesis 0.594647247019045 2.8372555542288542 0.0045503175124299 0.9999999999999064 0.1325857773270528 138 O60271,P42892,Q9Y3D6,P13591,Q6PCB8,Q06481,P00492,Q9UJU6,Q92859,P84095,Q14118,A0MZ66,P05067,P48681,Q9Y6N7,P16949,P05556,Q66K74,Q8TEY7,Q9UIW2,Q04721,Q07812,Q13740,P49768,P08238,P19022,Q14247,Q02750,O94813,Q8N0X7,O75955,Q13641,P07900,Q9Y4G8,P11047,Q6IBS0,O60678,Q13177,Q96PU5,P78559,Q9NUM4,Q14444,P43034,Q92692,P35613,Q9UNF0,Q15375,P29317,Q9UQB8,O14786 50 +Secondary alcohol metabolic process 0.6525581006317898 2.836897811041656 0.0045554189481209 0.9999999999999096 0.1325857773270528 45 P34913,Q9BQE5,P04062,O15118,P01130,P61916,Q14739,Q9UBM7,P05067,Q16850,Q15392,Q8WTV0 12 +Protein maturation 0.5710026662699684 2.835500208677353 0.0045753985182792 0.9999999999999208 0.1325857773270528 82 P42892,P78536,Q9UMY4,Q92542,O75503,P62942,Q92896,O00170,Q86UY6,Q10713,O75844,Q15392,Q99538,Q9BU89,Q9BXI6,O75976 16 +Regulation of response to external stimulus 0.5956889791753878 2.823391500130778 0.0047518506642694 0.9999999999999754 0.1350410777915342 142 Q9UMX5,Q96KB5,Q06481,O95219,P01130,O94898,Q9BXW9,P26583,P05067,Q9Y6N7,Q8NCG7,Q99538,Q9BUI4,P80303,P78536,P04792,O75179,P60900,P08238,P53634,Q6YHK3,O94992,P33527,P11279,P10586,O94813,P28070,Q13641,O95747,Q9Y3Z3,Q13177,P04439,Q15648,Q96J02,Q7Z739,P01889,P04062,P09429,Q53EL6,O43657,Q6UWE0,Q92692,O75844,Q08722,O14786 45 +Regulation of defense response 0.5623601734662824 2.8226264098846894 0.0047632040140237 0.9999999999999772 0.1350410777915342 97 Q96KB5,Q06481,O95219,P01130,Q9BXW9,P26583,P05067,Q8NCG7,Q9BUI4,P60900,P08238,P53634,O94992,P33527,P11279,P28070,Q9Y3Z3,Q13177,P04439,Q15648,Q96J02,Q7Z739,P01889,P04062,P09429,Q53EL6,O43657,Q6UWE0,Q92692,O75844,Q08722 31 +Adult behavior 0.8040765472805533 2.814159200469514 0.0048905002138328 0.99999999999999 0.135737174711361 20 Q92542,O15118,P51790,P05067,P50897,O75844 6 +Establishment of protein localization to vacuole 0.8219476255399176 2.809052208431243 0.0049687588117024 0.999999999999994 0.137329812871339 18 Q14108,Q99523,P13473 3 +Carbohydrate catabolic process 0.6419870670824684 2.802385435002108 0.0050726229412747 0.999999999999997 0.1377657428776714 49 Q14108,P10253,P05067,P16278,P17900 5 +Nervous system process 0.5691922354488518 2.795625314221712 0.0051799415598237 0.9999999999999986 0.1377657428776714 109 O14773,O94898,P01130,Q14118,P05067,P50897,Q99538,Q14108,P05556,P10253,P49768,P17900,P53634,Q92542,Q8N0X7,Q13641,Q06787,P11047,P07686,P78559,O43924,P04062,P43034,O75844,Q14203,Q9UQB8 26 +Regulation of system process 0.6039387328938525 2.7925488186600305 0.0052294575914255 0.999999999999999 0.1377657428776714 68 Q14126,P42892,Q02487,P04062,P22466,P10253,P05067,O75844,P53634 9 +Protein localization to lysosome 0.8399495477186644 2.784873333153673 0.0053548637048967 0.9999999999999996 0.1392264563273167 16 Q14108,Q99523,P13473 3 +Transition metal ion homeostasis 0.7435168977480515 2.781541076992846 0.0054101483649362 0.9999999999999996 0.1394646048137325 27 P02792,Q92859,Q15904,P05067,P02786 5 +Protein targeting to vacuole 0.8355981464389345 2.765033950791348 0.0056916871599463 1.0 0.1417957988032041 16 Q14108,Q99523,P13473 3 +Liposaccharide metabolic process 0.8353390935739069 2.7638512507970048 0.0057123573552522 1.0 0.1417957988032041 16 P04066,P06280,P07686,P16278,P17900,P06865 6 +Protein localization to vacuole 0.7860120328745496 2.758993629597458 0.0057979665203862 1.0 0.143138528997294 21 Q14108,Q99523,P13473 3 +Mononuclear cell migration 0.7475229272033671 2.757261914829877 0.0058287642958056 1.0 0.143138528997294 26 P04062,P09429,O94813,Q9Y624,P05067,Q08722,Q99538 7 +Phospholipid transport 0.85498645096191 2.755877523259441 0.0058534910763563 1.0 0.143138528997294 14 Q14108,Q9NV96,P08183,P01130,P61916,Q8WTV0 6 +Negative regulation of cell differentiation 0.5678433180813199 2.732084005390086 0.0062935091955573 1.0 0.1477657264746076 79 P05556,Q99523,O15347,Q06481,P09429,P01130,Q53EL6,O75179,Q9Y4G8,P67809,Q15375,P05067,Q92688,P49768,O14786,P06756 16 +Gliogenesis 0.6217816892992496 2.7263040930208895 0.0064047960725688 1.0 0.1477657264746076 55 P19022,P04062,Q07954,Q92542,P01130,P07942,Q9NR50,Q14118,P11047,P05067,P07686 11 +Neuromuscular process 0.7193050652337067 2.7179699855857544 0.0065683796228834 1.0 0.1477657264746076 29 O14773,P04062,P10253,P05067,P07686,P17900 6 +Positive regulation of inflammatory response 0.8251238694876653 2.717070034507863 0.0065862669372012 1.0 0.1477657264746076 16 P33527,O95219,Q53EL6,P01130,P05067,P53634 6 +Regulation of steroid metabolic process 0.8459819016642023 2.7161646816127183 0.0066043058047331 1.0 0.1477657264746076 14 P01130,P34913,Q13510,P22466 4 +Peptide catabolic process 0.8802308858683563 2.712805538585533 0.0066716245078075 1.0 0.1487659186859597 12 P42892,Q9UJ14,O14773,Q9UIQ6 4 +Leukocyte migration 0.6251718056922958 2.7042721186244147 0.0068454204860566 1.0 0.1502271527480014 51 P05556,P04062,P09429,O94813,Q9Y624,P84095,P35613,P05067,Q08722,Q99538,P78310 11 +Regulation of peptidase activity 0.5405390762879453 2.7036170326794893 0.0068589289583618 1.0 0.1502271527480014 87 Q6YHK3,Q07954,Q06481,Q92542,P09429,P04080,P78318,Q15375,P05067,Q92530,Q92688,Q15392,Q9Y6N7,Q99538,O95831,O43847,P23396 17 +Negative regulation of cell development 0.7367498773551441 2.6987804826480537 0.0069594065126643 1.0 0.1502271527480014 26 Q06481,P01130,Q9Y4G8,Q15375,P49768,O14786 6 +Vascular transport 0.7976993905066049 2.6935921935045486 0.0070686593245039 1.0 0.1502271527480014 18 P33527,Q07954,P08183,P30825,Q96QD8,P02786 6 +Glial cell differentiation 0.6522666518129092 2.6916734973660112 0.0071094508734286 1.0 0.1502271527480014 41 P19022,P04062,Q07954,Q92542,P01130,Q9NR50,Q14118,P11047,P05067 9 +Negative regulation of nervous system development 0.7779575515663004 2.685302047086742 0.0072464285992077 1.0 0.1502271527480014 20 Q06481,P01130,Q9Y4G8,Q15375,P49768,O14786 6 +Regulation of synapse structure or activity 0.680312193970301 2.6851370956064993 0.0072500060767421 1.0 0.1502271527480014 36 P19022,Q14444,Q9UJU6,Q13641,P43034,Q14118,P07437,Q15375,P05067,P50897,Q14203,Q9UQB8 12 +Protein targeting to lysosome 0.8562921392841937 2.684092964426943 0.0072726880484508 1.0 0.1502271527480014 13 Q14108,Q99523,P13473 3 +Regulation of leukocyte proliferation 0.7333366569268251 2.6801617568881437 0.0073586591288954 1.0 0.1502271527480014 26 P09429,P22466,P30825,P02786,P04439,Q9NPF0,P10644 7 +Neuromuscular process controlling balance 0.8550497380361555 2.678721166637001 0.0073903907632801 1.0 0.1502271527480014 13 P17900,P10253,O14773,P05067 4 +Positive regulation of defense response 0.6263181423896245 2.672674820510601 0.0075249154297103 1.0 0.1502271527480014 47 O94992,P33527,O95219,P09429,P01130,P11279,Q53EL6,Q92692,P05067,Q08722,P53634 11 +Regulation of endocytosis 0.610792861723214 2.6708470167476683 0.0075660120831855 1.0 0.1503602038767202 57 Q9UKS6,Q9UMY4,Q06481,Q07954,O00560,Q6UWE0,Q06787,Q9UNF0,P05067,P50897,P49768,Q9H223,P06756,Q96PU5 14 +Biological adhesion 0.6068263880155906 2.6661176731900347 0.0076732829421417 1.0 0.1520326963656882 197 Q14126,P13591,Q6PCB8,O60245,P23396,P30825,Q92859,Q14118,P05067,Q9Y6N7,P02786,P78310,P05556,P78536,Q08380,Q9UM22,Q14517,Q14574,P48960,Q13740,P49768,Q13308,P19022,Q02487,P10586,Q08431,Q13641,P11047,P04439,Q8WTV0,Q08722,P43121,P06756,P10644,P09429,P07942,Q9P273,Q9Y624,Q92692,P35613,Q15375,P29317,Q9UQB8,O14786 44 +Ceramide metabolic process 0.790696204140798 2.6599257920302373 0.0078157869645871 1.0 0.1525873015829698 18 Q13510,Q8NCC3,P06280,P07686,P17900,P06865 6 +Sterol homeostasis 0.867122601199317 2.6576105738344684 0.007869676973248 1.0 0.1531560210947501 12 P34913,O15118,P01130,P61916,Q8WTV0 5 +Dendrite development 0.607914449943632 2.649384301007411 0.00806385777063 1.0 0.1549654045169976 57 Q9UJU6,P00492,Q12834,P05067,P05556,P49768,Q13641,Q9Y4G8,Q06787,O60678,Q13177,Q96PU5,P78559,Q9NUM4,Q14444,P43034,P46108,Q9UQB8,O14786 19 +Anion transport 0.5635790525499299 2.6486900617889457 0.0080804399132456 1.0 0.1549654045169976 77 Q6PCB8,P30825,Q9BXP2,O00400,P07602,Q9C0H2,P05556,P51798,P08183,Q9UHG3,Q15043,P33527,P51790,Q7L0J3,P11166,Q96QD8,Q08722,Q9H2J7,P08195 19 +Glial cell development 0.7628404283572463 2.6422745567758343 0.0082351268958418 1.0 0.1567524558611025 21 Q07954,Q92542,P01130,Q9NR50,Q14118,P11047,P05067 7 +Regulation of cell activation 0.5729501486186372 2.6407607997384366 0.0082720099179482 1.0 0.1567524558611025 73 O15347,O95219,P22466,P01130,P30825,P11279,P09429,Q9Y624,Q92692,Q08722,P02786,P04439,P53634,Q9NPF0,P10644,P23396 16 +Regulation of tube size 0.8793374287866158 2.6399113320618763 0.0082927720644061 1.0 0.1567524558611025 11 P42892 1 +Regulation of endothelial cell migration 0.694442237860194 2.6236224386363904 0.0087000168574891 1.0 0.1635106025387525 31 Q13685,P42785,P09429,O94813,P67870,P29317,Q99538,Q8WTV0,O14786 9 +Amyloid beta clearance 0.8748176809063907 2.621223464642258 0.008761481089389 1.0 0.1637301778579571 11 P01130,Q07954 2 +Neuron projection organization 0.7222426282812894 2.6193427451743276 0.0088099381188755 1.0 0.1641693284588195 26 Q14444,Q9UJU6,P43034,Q14203,P05067,O60678,P49768,Q99538,P78559,Q9UQB8 10 +Intracellular lipid transport 0.8397419478353191 2.612229683146147 0.0089953797730508 1.0 0.1666805863299398 13 P01130,P61916,O43772 3 +Lysosomal protein catabolic process 0.9502514146721248 2.605825871872292 0.0091653042697812 1.0 0.1679456099092439 8 O14773,Q07954,P01130,P13473,Q9NUM4 5 +Protein catabolic process in the vacuole 0.9502514146721248 2.605825871872292 0.0091653042697812 1.0 0.1679456099092439 8 O14773,Q07954,P01130,P13473,Q9NUM4 5 +T cell proliferation 0.7269615956554242 2.602956419400238 0.0092423701409465 1.0 0.1679456099092439 25 Q92542,P09429,P30825,P17931,P17812,Q07812,P02786,P04439,Q96J02,P10644,P23396 11 +Monovalent inorganic cation homeostasis 0.6858245312285911 2.5987737459847864 0.0093557415408829 1.0 0.1686378341806631 32 O75503,Q93050,Q15904,P51790,Q9BXP2,P50897,Q9NUM4 7 +Associative learning 0.8194085753095111 2.597774423141608 0.0093830111447434 1.0 0.1686378341806631 14 Q99538,Q13641,P05067,P50897 4 +Tissue migration 0.6008805063050929 2.5967087628599965 0.0094121690725514 1.0 0.1687009486627894 57 P05556,Q13685,P42785,P09429,O94813,P67870,P29317,Q9Y6N7,Q99538,Q8WTV0,O14786 11 +Cellular transition metal ion homeostasis 0.7401513395170904 2.5955335386609604 0.0094444185125603 1.0 0.168818980912017 23 P02786,Q15904,P05067,P02792 4 +Protein processing 0.6038711559372529 2.5942710899200025 0.009479171258087 1.0 0.1689809987417254 55 P42892,P78536,Q9UMY4,Q92542,O75503,Q92896,Q10713,Q15392,Q9BXI6,O75844,Q99538,O75976 12 +Antigen processing and presentation 0.7094042077144863 2.5922419655627587 0.0095352681017379 1.0 0.1694680219883967 27 P01889,P04062,Q9UIQ6,P04439,Q99538 5 +Negative regulation of developmental process 0.5476069818915044 2.5904957713619132 0.0095837798996174 1.0 0.1694680219883967 110 O15347,Q06481,O94898,P01130,P05067,P02786,Q99538,P05556,Q99523,O75179,Q92688,P49768,Q8N0X7,Q9Y4G8,P67809,P13693,P06756,P09429,Q53EL6,Q15375,P29317,O14786 22 +Regulation of epithelial cell migration 0.6178412142069619 2.5879652961185733 0.0096544706827204 1.0 0.1698051020078471 44 Q13685,P42785,P09429,O94813,P67870,P29317,Q99538,Q8WTV0,O14786 9 +Transforming growth factor beta receptor signaling pathway 0.7238949342595629 2.586303510342388 0.0097011464516851 1.0 0.1701710436244937 25 P05556,Q6YHK3,Q06481,O00560,Q13526,Q92896,P62942 7 +Negative regulation of proteolysis 0.5722176117930455 2.57587729217482 0.0099986122793727 1.0 0.1720465994506243 70 Q96KB5,Q06481,O94898,P78318,O00560,P61201,P05067,Q07954,P60520,Q96K76,Q92530,P49768,P08238,Q04323,Q6YHK3,Q92896,Q15392,P78559,Q9C0C9,Q9UMY4,P62913,P04080 22 +Learning 0.742797727880344 2.573543420924374 0.0100663014945148 1.0 0.1724378417471835 22 Q99538,P05067,P50897,Q13641 4 +Adult locomotory behavior 0.8035675471486099 2.570312385777674 0.0101606846258226 1.0 0.1736025544640555 15 O15118,P51790,P05067,O75844,P50897 5 +Antigen processing and presentation of peptide antigen 0.8106056508022491 2.558157423770108 0.010522844373292 1.0 0.1779078554281962 14 P04439,P01889,Q9UIQ6,Q99538 4 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6830853118170189 2.556526235131407 0.0105723098457191 1.0 0.1779078554281962 31 Q6YHK3,Q9C0C9,P78536,Q07954,O00560,Q13526,Q8N0X7,P67870,Q92859,Q92896,Q04721,P62942 12 +Tissue remodeling 0.7522626401050162 2.5564396117740555 0.0105749424555221 1.0 0.1779078554281962 20 P02786,O14773,P38571 3 +Artery development 0.8583285131402089 2.552666270589456 0.0106901871567721 1.0 0.1779151732049782 11 P01130,Q07954,O14786 3 +Regulation of mononuclear cell migration 0.7567449515289398 2.548965636227008 0.010804294579426 1.0 0.1779151732049782 19 P78536,P09429,O94813,P46108,O95747,P05067,Q08722,Q99538 8 +Alcohol metabolic process 0.5229262641879071 2.5411246711196194 0.0110496511315567 1.0 0.1794681608478527 87 P34913,Q9BQE5,Q13510,P04062,O15118,P01130,P61916,Q14739,Q9UBM7,Q15126,P05067,Q16850,Q15392,Q8WTV0,Q9NX62 15 +Cellular monovalent inorganic cation homeostasis 0.6880429922221124 2.5382212568929843 0.0111417519493435 1.0 0.1805183357703983 29 O75503,Q93050,Q15904,P51790,P50897,Q9NUM4 6 +Regulation of neurogenesis 0.5799523230836005 2.5350474369870692 0.0112432099759836 1.0 0.1816500700115743 64 Q06481,P01130,Q9UJU6,P26583,Q14118,A0MZ66,Q9Y6N7,P55209,Q9UIW2,P49768,Q02750,O94813,Q8N0X7,Q9Y4G8,Q6IBS0,Q14444,P43034,Q15375,Q15154,Q15382,Q9UQB8,O14786 22 +Lipid homeostasis 0.7068730777441901 2.5343121059033624 0.0112668331658136 1.0 0.1816500700115743 26 P34913,O15118,P01130,P61916,Q5BJF2,Q8WTV0 6 +Regulation of phagocytosis 0.7632327377024812 2.526489951122994 0.0115208684272682 1.0 0.1848396890599289 18 P09429,Q06481,Q08431,Q8WTV0,P06756 5 +Vacuolar acidification 0.8517323805388277 2.525073836751078 0.0115673982776862 1.0 0.1851346614856941 11 O75503,Q9NUM4,P50897 3 +Glycosphingolipid metabolic process 0.9547128516681356 2.519792392078292 0.0117424069315272 1.0 0.1857519333700412 7 P06280,P07686,P16278,P17900,P06865 5 +Response to peptide 0.5342612405653747 2.5187146171232246 0.0117784078252598 1.0 0.1857519333700412 103 Q99523,P33527,Q9BSK2,Q07954,Q06481,P22466,Q9H1E3,Q14118,Q9NR50,P35613,P05067,O00459,Q99538,Q9UQB8,Q15043,P11166 16 +Hindbrain development 0.6475592024749497 2.5117847645318285 0.0120122327434888 1.0 0.188177735063883 37 P05556,P04062,Q92542,P54802,Q5KU26,O95456 6 +Glycolipid catabolic process 0.9714455681142188 2.510628081098567 0.0120516594009938 1.0 0.188177735063883 6 P04066,P06280,P07686,P17900,P06865 5 +Ceramide catabolic process 0.9714455681142192 2.510628081098567 0.0120516594009938 1.0 0.188177735063883 6 Q13510,P06280,P07686,P17900,P06865 5 +Neurotransmitter transport 0.6832023312953626 2.5100264747593286 0.0120722110363269 1.0 0.188177735063883 29 P05556,Q96QD8,P50897,P49768,Q9H2J7,Q7L0J3,Q4J6C6 7 +Developmental growth involved in morphogenesis 0.6008454625499539 2.50865473079505 0.0121191877538997 1.0 0.1884633972698642 49 O60271,Q9UJU6,A0MZ66,P05067,P05556,Q9UIW2,Q13740,P08238,Q13308,Q14247,O94813,Q8N0X7,P07900,P11047,Q96PU5,Q15648,P43034,Q15375,O14786 19 +Developmental maturation 0.6050521859243309 2.5051973875198494 0.0122383073359737 1.0 0.1889755531831816 45 Q9Y2W6,P04062,P22466,O75179,O75503,Q14118,P51790,P05067,Q08J23 9 +Regulation of leukocyte migration 0.6817479389661866 2.5015360185722457 0.0123655863388807 1.0 0.1904937398996663 29 P09429,O94813,P84095,P05067,Q08722,Q99538 6 +Carbohydrate derivative catabolic process 0.6597531531161775 2.4957590341972513 0.0125687949919754 1.0 0.1920821565995267 34 P04066,P15586,P54802,P06280,Q9BTY2,P07686,P16278,Q9H773,P17900,P06865 10 +Positive regulation of chemotaxis 0.7566904436627545 2.4943675476598433 0.0126181809711776 1.0 0.1920821565995267 18 P04792,P78536,P09429,O94813,Q13641,Q99538,O14786 7 +Positive regulation of endocytosis 0.7273948926634938 2.493110854403048 0.0126629304832024 1.0 0.1920821565995267 22 Q06481,P50897 2 +Immune effector process 0.5454358106431212 2.493002660662137 0.0126667897073649 1.0 0.1920821565995267 77 P01889,P49768,O15400,P78536,Q07954,Q06481,P11279,O95219,P09429,O75179,Q92692,P05067,Q9UQ84,Q08722,P02786,P04439,P53634,P13051 18 +Regulation of ph 0.7067045858788251 2.492306969441211 0.0126916295929948 1.0 0.1920821565995267 25 O75503,Q15904,P51790,P50897,Q9NUM4 5 +Regulation of cellular ph 0.7067045858788251 2.492306969441211 0.0126916295929948 1.0 0.1920821565995267 25 O75503,Q15904,P51790,P50897,Q9NUM4 5 +Blood vessel endothelial cell migration 0.7064177943038975 2.490729411749824 0.0127481166145897 1.0 0.1920821565995267 25 P05556,P42785,P09429,O94813,P67870,P29317,Q9Y6N7,Q8WTV0,O14786 9 +Membrane invagination 0.812023173471019 2.490378752868744 0.0127607027111573 1.0 0.1920821565995267 13 Q08431,P51790,Q06481 3 +Transcytosis 0.9189578098697212 2.48668253389926 0.0128940403964787 1.0 0.1932050062142084 8 P55899 1 +Chloride transport 0.8266693559934698 2.4847845475249697 0.012962986328749 1.0 0.1937966456147981 12 P08183,P51790,Q9BXP2,Q9UHG3,Q9C0H2 5 +Cellular ion homeostasis 0.5279857783611057 2.4832554146248675 0.0130187703594164 1.0 0.1941892776059896 100 P49768,P09429,O75503,Q93050,P02792,Q9HC07,Q15904,P51790,P05067,P07686,P50897,P02786,P62942,Q7L0J3,Q96PU5,Q9NUM4,Q15043,P06756 18 +Ph reduction 0.7734018446893325 2.4758181741402803 0.0132931257497972 1.0 0.1973864135037613 16 P51790,O75503,Q9NUM4,P50897 4 +Leukocyte cell cell adhesion 0.6196720716140236 2.4726699668344665 0.0134107926040996 1.0 0.1982386376399263 41 P05556,P09429,P30825,Q9Y624,Q08722,P02786,P04439,P10644 8 +Cerebellar cortex development 0.7905074149365519 2.4669542047806217 0.0136267783966195 1.0 0.2009797046927426 14 Q5KU26,P54802,P04062 3 +Regulation of cell cell adhesion 0.5982190543963286 2.464062303962221 0.0137372230176784 1.0 0.2010726357434704 46 P09429,P30825,Q9P273,Q9Y624,Q15375,Q08722,P02786,P04439,P10644 9 +Leukocyte mediated cytotoxicity 0.789064180079137 2.460364454621858 0.0138795989313944 1.0 0.2015452577719927 14 P01889,O15400,P11279,Q92692,P46108,P07437,P04439,P53634 8 +Cell morphogenesis 0.5840746812194159 2.455850509454571 0.0140551611569461 1.0 0.2036450442519644 195 O60271,P42892,P13591,Q6PCB8,Q06481,Q13596,P00492,P15311,Q9UJU6,Q92859,P84095,P47756,A0MZ66,Q14118,P05067,P46934,P48681,Q9Y6N7,P16949,Q99828,P05556,Q66K74,Q8TEY7,Q9UIW2,Q14517,Q04721,Q13740,P49768,P08238,P19022,Q14247,Q12959,Q02750,O94813,Q8N0X7,O75955,Q13641,P07900,Q9Y4G8,P11047,Q6IBS0,P07686,P38571,O60678,Q96PU5,Q13177,P78559,Q9BYJ9,Q14651,Q9NUM4,Q15648,P06756,Q13418,P07942,Q14444,Q9Y624,O60749,P43034,P46108,P35613,Q9UNF0,Q15375,O75844,P29317,Q16181,Q9UQB8,Q9UEE9,O14786 68 +Iron ion homeostasis 0.7320669840961094 2.453662125861972 0.0141409778740366 1.0 0.2042607533470053 20 P02786,P02792,Q92859,Q15904 4 +Organic hydroxy compound transport 0.6528671278530469 2.453009167322756 0.0141666728240119 1.0 0.2042607533470053 34 Q07954,O15118,P01130,P22466,P61916,Q8WTV0 6 +Regulation of nervous system process 0.8033631602721175 2.4519220403957083 0.0142095443885015 1.0 0.2042607533470053 13 P04062,Q14118,P05067,P53634,Q9UQB8 5 +Positive regulation of mononuclear cell migration 0.8342817075153064 2.4516101639216297 0.0142218645535008 1.0 0.2042607533470053 11 Q99538,P05067,P09429,Q08722 4 +Neuron development 0.5895341721254324 2.450039898843298 0.0142840385729217 1.0 0.2047067663021329 211 O60271,P42892,Q9NV96,P13591,Q6PCB8,Q06481,O94898,Q9UJU6,O75503,Q92859,P84095,Q14118,P05067,P50897,Q9Y6N7,P16949,Q9H4M9,Q14108,P05556,Q8TEY7,Q15643,P54802,Q13740,P49768,Q13308,Q9NQX7,P19022,P10586,O94813,Q8N0X7,Q13641,Q9Y4G8,Q06787,P11047,Q32P28,Q96PU5,P78559,Q9NUM4,O75312,P04062,P09429,P07942,Q14444,Q9P273,Q8N3F8,P43034,P35613,Q15375,P29317,Q9UQB8,O14786 51 +Negative regulation of immune system process 0.5945658592602951 2.445719021480794 0.0144563613551251 1.0 0.20672596737829 47 P01889,P09429,P22466,P01130,P28070,O94813,Q08722,P04439,P10644 9 +Cellular component morphogenesis 0.5610036979226213 2.4432603197058373 0.0145552341161827 1.0 0.2075016495827895 152 O60271,P42892,Q9Y3D6,P13591,Q6PCB8,Q06481,P00492,Q9UJU6,Q92859,P84095,Q14118,A0MZ66,P05067,P48681,Q9Y6N7,P16949,P05556,Q66K74,Q8TEY7,Q9UIW2,Q04721,Q07812,Q13740,P49768,P08238,P19022,Q14247,Q02750,O94813,Q8N0X7,O75955,Q13641,P07900,Q9Y4G8,P11047,Q6IBS0,O60678,Q13177,Q96PU5,P78559,Q9NUM4,P10644,Q14444,P43034,Q92692,P35613,Q9UNF0,Q15375,P29317,Q9UQB8,O14786 51 +Negative regulation of supramolecular fiber organization 0.5963241242981471 2.442802892636538 0.0145736944523029 1.0 0.2075016495827895 45 Q15691,Q9NYL9,P01130,P07737,P47756,P16949,Q99828,P04350,P46821,Q9UHV9,P60983,Q99471,Q02790,O94813,Q9Y6W5,Q6IBS0,Q13177,P29372,P35080,Q9Y624 20 +Response to amyloid beta 0.8798768068907238 2.437763691218879 0.0147784313066496 1.0 0.2090276511643065 9 Q99538,P33527,P05067,Q07954 4 +Cellular response to amyloid beta 0.8798768068907238 2.437763691218879 0.0147784313066496 1.0 0.2090276511643065 9 Q99538,P33527,P05067,Q07954 4 +Apoptotic cell clearance 0.8553790966226602 2.437041521267179 0.0148079789362369 1.0 0.2090276511643065 10 Q07954,Q08431,P84095,Q8WTV0,P06756 5 +Lipoprotein metabolic process 0.721988334163053 2.432202539324229 0.0150073127498673 1.0 0.2110414043246155 21 P01130,P04062,P50897,P06756 4 +Bone remodeling 0.8541557757430323 2.4320218026640728 0.0150148034697354 1.0 0.2110414043246155 10 P02786,O14773 2 +Positive regulation of synaptic transmission 0.7428923499161868 2.426190731847538 0.0152582489208212 1.0 0.2139093881520067 18 Q99538,P05067 2 +Regulation of t cell proliferation 0.7402742713491597 2.4131887132917016 0.0158136294767656 1.0 0.2140371495847009 18 P09429,P30825,P02786,P04439,P10644 5 +Bone resorption 0.9258735240213134 2.412075760752818 0.0158619851450019 1.0 0.2142507972973771 7 O14773 1 +Intracellular sterol transport 0.8721750751650417 2.407088442478892 0.0160802751114612 1.0 0.2156926707194066 9 P01130,P61916 2 +Production of molecular mediator involved in inflammatory response 0.7769371157399922 2.4047768233689064 0.0161823449497231 1.0 0.2156926707194066 14 Q8IV08,Q53EL6,O95219,Q06481 4 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.7582321668967738 2.403642121222825 0.0162326559013497 1.0 0.2156926707194066 16 Q6YHK3,P78536,Q07954,Q13526,Q92896,P62942 6 +Plasma lipoprotein particle clearance 0.807843491681939 2.4030541454263763 0.0162587798737545 1.0 0.2156926707194066 12 P01130,P38571 2 +Glycoside metabolic process 0.8709919361342584 2.4023658058866877 0.016289409979133 1.0 0.2156926707194066 9 Q9BTY2,P04066,P06280 3 +Positive regulation of leukocyte proliferation 0.7673503770073207 2.402287196411323 0.0162929112100016 1.0 0.2156926707194066 15 P09429,P30825,P02786,P04439,Q9NPF0 5 +Regulation of plasma lipoprotein particle levels 0.7673325544587641 2.402203632549505 0.0162966338320986 1.0 0.2156926707194066 15 P01130,P38571 2 +Regulation of chemotaxis 0.6646002056078664 2.40075518161533 0.0163612786105702 1.0 0.2157622559300359 29 P09429,O94813,Q13641,Q9Y6N7,Q99538,O14786 6 +Regulation of lipase activity 0.8180091715048353 2.3824938883085856 0.017195817419537 1.0 0.2220693759308391 11 Q99523,P50897 2 +Long term synaptic potentiation 0.8177503687022826 2.381389849826566 0.0172474480667308 1.0 0.2220693759308391 11 Q99538,P05067 2 +Mucopolysaccharide metabolic process 0.8641604419931718 2.375043338535464 0.0175468898187809 1.0 0.2220693759308391 9 P15586,O43505,P16278 3 +Astrocyte differentiation 0.7858924346361057 2.3737722836349584 0.0176074056617414 1.0 0.2220693759308391 13 P01130,P05067,Q07954,P11047 4 +Dendrite morphogenesis 0.6352055786732693 2.370540331695901 0.0177621059214563 1.0 0.2220693759308391 35 P05556,Q14444,Q9UJU6,Q13641,Q9Y4G8,P43034,O60678,Q96PU5,Q9UQB8,Q9NUM4,O14786 11 +Response to catecholamine 0.721083041068082 2.368989596925181 0.017836755155256 1.0 0.2220693759308391 19 P05067 1 +Erk1 and erk2 cascade 0.5927177286776627 2.3666897313440027 0.0179479721590942 1.0 0.2220693759308391 43 P09429,Q13641,Q9Y4G8,Q86VI3,Q15375,P05067,P29317,O14786,P06756 9 +Regulation of cell development 0.5155676976938274 2.3661465287085193 0.0179743288916907 1.0 0.2220693759308391 100 Q06481,P01130,Q9UJU6,P26583,Q14118,A0MZ66,Q9Y6N7,P55209,Q99828,Q9UIW2,Q04721,P49768,Q02750,O94813,Q8N0X7,Q9Y4G8,Q6IBS0,Q13418,Q14444,Q9Y624,P43034,P46108,Q15375,Q15154,Q15382,Q9UQB8,O14786 27 +Ion homeostasis 0.5313675801072985 2.3661200698046887 0.0179756135695361 1.0 0.2220693759308391 120 O75503,Q92859,Q9BXP2,P05067,Q8NE01,P50897,P02786,P62942,Q93050,Q9HC07,Q15043,P02792,Q15904,P51790,P07686,Q7L0J3,Q96PU5,Q9NUM4,P06756,P09429 20 +Cellular response to peptide 0.5354005621177085 2.363849450841711 0.0180861605861304 1.0 0.2220693759308391 75 P33527,Q06481,Q07954,Q9H1E3,P05067,O00459,Q99538,Q9UQB8,Q15043,Q9BSK2 10 +Synapse organization 0.5375051594888639 2.3619869072169637 0.0181772841583767 1.0 0.2220693759308391 74 P19022,P10586,Q14444,Q9UJU6,O00560,Q13526,Q13641,P43034,Q14118,P11047,P07437,Q15375,P05067,P49768,Q99538,Q14203,Q9UQB8,O14786 18 +Neuron recognition 0.885565415974213 2.3575889247382618 0.0183940492006184 1.0 0.2220693759308391 8 O14786,Q6PCB8,P05067,Q9Y6N7 4 +Myeloid leukocyte differentiation 0.6329945401870624 2.35645646517618 0.0184502301684277 1.0 0.2220693759308391 35 Q6YHK3,P04062,Q15904,P05067,P29317,P02786 6 +Response to transforming growth factor beta 0.6371709419953486 2.3547276142437794 0.0185362875714827 1.0 0.2220693759308391 34 P05556,Q6YHK3,Q06481,O00560,Q13526,Q92896,P62942 7 +Low density lipoprotein particle clearance 0.8114209312775783 2.354341979462984 0.0185555312453902 1.0 0.2220693759308391 11 P01130,P38571 2 +Positive regulation of cell projection organization 0.5407635304000936 2.3514088408670726 0.0187024716725676 1.0 0.2232750833035155 72 Q14108,Q9NV96,Q9P2S5,Q14444,Q9UJU6,O94813,Q9P273,Q9Y4G8,Q06787,P43034,Q9UQB8,Q9NUM4,Q32P28,Q9Y6N7,Q13308,P11233,Q9H4M9,O14786 18 +Vasculature development 0.5180125676313573 2.3502169619052 0.0187624710728588 1.0 0.2232750833035155 105 P01130,Q14118,Q9Y6N7,P05556,Q13685,P42785,Q07954,O75179,Q92688,P49768,P19022,Q08431,O94813,Q9Y4G8,P43121,P06756,Q53EL6,P35613,P29317,O14786 20 +Developmental cell growth 0.5761049590925913 2.34474010239207 0.0190403467167776 1.0 0.2255718153422329 51 O60271,P05556,Q14247,Q9UJU6,O94813,Q9UIW2,Q8N0X7,P07900,P43034,P11047,A0MZ66,Q15375,P05067,Q13740,Q96PU5,P08238,O14786 17 +Positive regulation of leukocyte migration 0.7363296766463131 2.3442327164183356 0.0190662708011981 1.0 0.2255718153422329 17 Q99538,P05067,P09429,Q08722 4 +Regulation of cell junction assembly 0.6208421774008499 2.338525042545301 0.0193600281388899 1.0 0.2272914420672454 37 Q9Y624,Q13641,Q15375,P05067,P29317,O14786 6 +Endosomal transport 0.5069282156510861 2.3375873235905167 0.0194086661689172 1.0 0.2272914420672454 85 O60271,Q99523,O15260,Q9Y3E7,Q9C0C9,Q9UMY4,O95219,Q9UEU0,O75503,Q8N3F8,Q8NBN3,Q15904,Q96L92,Q9BXI6,Q14203,P42566,Q9H4M9,Q4J6C6 18 +Carbohydrate metabolic process 0.545431531466184 2.335862534607402 0.0194984071467201 1.0 0.2272914420672454 145 Q7LGA3,P06280,Q9BTY2,P05067,P06865,Q14108,P04066,P10253,O00754,P16278,P17900,Q9Y2E5,Q15043,Q9NX62,Q92520,Q8IW92,Q10713,P07686,O60476,O43505,O75844,P08195 22 +Metencephalon development 0.6453413100647285 2.3294787799087446 0.0198337158819723 1.0 0.2284871857646482 31 Q5KU26,P54802,P04062,Q92542 4 +Regulation of receptor recycling 0.8772302345239605 2.325047988563904 0.0200693943164642 1.0 0.230798034639339 8 P42892 1 +Positive regulation of hydrolase activity 0.5168858774601837 2.3240896749883535 0.0201206883139144 1.0 0.2309840972581661 107 Q13526,P26583,P84095,P05067,Q9Y6N7,Q9BXI6,Q99538,P07602,P05556,Q0IIM8,Q92688,Q92542,Q9Y4G8,Q9NUM4,O95831,P09429,Q9Y624,P29317,P23396 19 +Positive regulation of t cell proliferation 0.8503874832869817 2.3196794965496137 0.0203582218032005 1.0 0.2324937205233565 9 P30825,P04439,P09429,P02786 4 +Regulation of blood circulation 0.6500475837725054 2.3142389528403062 0.0206546183644975 1.0 0.2350624214561677 29 Q14126,P42892,Q02487,P10253,O75844 5 +Glycoside catabolic process 0.949764985618391 2.3121686457993142 0.0207683914196592 1.0 0.2357808752129259 5 Q9BTY2,P04066,P06280 3 +Regulation of long term synaptic potentiation 0.8980028680590593 2.306636060227266 0.0210751174988108 1.0 0.2381995238954945 7 Q99538,P05067 2 +Response to hepatocyte growth factor 0.8722788754221905 2.3056575069925747 0.0211297772438288 1.0 0.2382828308785624 8 Q99538,Q06481 2 +Regulation of inflammatory response 0.6006831087465913 2.30520782856015 0.0211549366423047 1.0 0.2382828308785624 40 P33527,Q96KB5,O95219,Q9BXW9,P01130,P28070,P04062,Q53EL6,P05067,P60900,P53634,Q08722 12 +Lymphocyte migration 0.7845449951815361 2.3007466894614916 0.0214059533506636 1.0 0.2395261154922095 12 P78536,P04062,Q9Y624,O95747,P05067 5 +Digestion 0.7696996784513792 2.3006580102688 0.0214109692778077 1.0 0.2395261154922095 13 P01130,Q8WTV0 2 +Regulation of systemic arterial blood pressure 0.8698145776920552 2.29599013269754 0.0216764455674633 1.0 0.2414925819026881 8 P42892 1 +Positive regulation of cell activation 0.582748065949626 2.2956327954945825 0.0216968859690618 1.0 0.2414925819026881 43 O95219,P09429,P30825,P11279,Q92692,Q08722,P02786,P04439,P53634,Q9NPF0 10 +Inorganic anion transport 0.6498359209200388 2.293191080082394 0.0218370064661064 1.0 0.2421045142730159 28 P33527,P08183,P51790,Q9BXP2,Q9UHG3,Q15043,Q9C0H2 7 +Endocrine process 0.8938815194457412 2.290932258280997 0.0219673319226134 1.0 0.2428590073730275 7 P42892 1 +Regulation of lipid transport 0.7251920834660709 2.2893444649462356 0.0220593461055091 1.0 0.2434302436400327 17 Q9NV96,P06756,Q07954,P22466 4 +Lysosomal lumen acidification 0.9104954295184062 2.285021992681936 0.0223115382263083 1.0 0.2447473548363178 6 O75503,P50897 2 +Negative regulation of hydrolase activity 0.5371496623587699 2.2848065498112016 0.0223241734420478 1.0 0.2447473548363178 70 Q6YHK3,Q99523,O95429,Q9C0C9,Q06481,Q07954,P04080,P78318,Q9Y624,O00170,P61201,Q96K76,P05067,Q92530,Q15392,P62942,Q15043,Q04323 18 +Digestive system process 0.7797444721769012 2.27950670878716 0.0226369616268979 1.0 0.2461255100524545 12 P01130,Q8WTV0 2 +Regulation of axonogenesis 0.6367077227845587 2.2766504825270344 0.0228071057006087 1.0 0.2469648813081376 31 P19022,Q13177,Q02750,Q9UJU6,O94813,Q9UIW2,Q8N0X7,P43034,A0MZ66,Q15375,Q9Y6N7,P49768,O14786 13 +Amyloid precursor protein metabolic process 0.667912741653602 2.2760808741290353 0.02284116957623 1.0 0.2469648813081376 25 Q9NQX7,P78536,Q92542,Q13526,Q15392,P62942 6 +Golgi to vacuole transport 0.8645462883259669 2.275285539613865 0.0228888063265277 1.0 0.2469648813081376 8 P11279,Q99523 2 +Regulation of receptor mediated endocytosis 0.6539802947357849 2.274849075933877 0.0229149850818823 1.0 0.2469648813081376 27 O00560,P05067,P50897,P49768,P06756 5 +Artery morphogenesis 0.9061871692479716 2.2688486867717996 0.0232775290747955 1.0 0.2491224361700625 6 P01130,Q07954 2 +Skin development 0.6003840432493893 2.2680002515091875 0.0233291913470292 1.0 0.2491224361700625 39 Q6YHK3,Q13510,P04062,P22466,O75844,Q15392 6 +Positive regulation of epithelial cell proliferation 0.678230608053997 2.262980602848733 0.0236368850355539 1.0 0.2502863830300981 23 Q8N122,P78536,P09429,P07942,P26583,Q86VI3,P11047,O95747,Q04721,O14786 10 +Cholesterol efflux 0.8612014746770815 2.2621139626434914 0.0236903631543294 1.0 0.2502863830300981 8 P61916,Q07954,O15118 3 +Sulfur compound catabolic process 0.8359114938589209 2.261086926459836 0.0237538747808845 1.0 0.2502863830300981 9 P15586,P16278 2 +Negative regulation of neuron apoptotic process 0.6410504345299064 2.260291713652677 0.0238031519274741 1.0 0.2502863830300981 29 O75312,P04062,P08238,P48681,P50897,P49768,Q99538,Q01105,O14786 9 +Regulation of cellular response to growth factor stimulus 0.5991623290972368 2.259706615026747 0.0238394654799811 1.0 0.2502863830300981 39 Q6YHK3,Q9C0C9,P78536,O94813,O00560,Q13526,Q8N0X7,Q92859,Q92896,Q04721,Q9Y6N7,P62942 12 +Sterol transport 0.6772668081004779 2.25769508645324 0.0239646757856186 1.0 0.2502863830300981 23 P01130,P61916,Q07954,O15118 4 +Heterotypic cell cell adhesion 0.7747700446123309 2.257439463324245 0.0239806281629262 1.0 0.2502863830300981 12 P05556,Q14126,Q02487,P78310,P06756 5 +Metal ion homeostasis 0.4944480620547678 2.254931120929615 0.0241376525455916 1.0 0.2502863830300981 89 P49768,P09429,P02792,Q92859,Q9HC07,Q15904,Q9BXP2,P05067,P07686,Q8NE01,P02786,P62942,Q7L0J3,Q96PU5,Q15043,P06756 16 +Chaperone mediated autophagy 0.8585742468924811 2.2517538463962667 0.0243378317988525 1.0 0.2502863830300981 8 P13473 1 +Regulation of cell projection organization 0.5300572333753086 2.2512370460351914 0.0243705276917849 1.0 0.2502863830300981 135 Q9NV96,O94898,P15311,Q9UJU6,Q12834,P84095,P47756,A0MZ66,P07737,P46934,Q9Y6N7,Q9BXI6,Q8TC07,Q4KMP7,Q9H4M9,Q99828,Q14108,Q9UIW2,P50395,O60493,P49768,Q13308,P51114,Q9NQX7,P19022,Q02790,P63000,Q02750,P10586,O94813,Q8N0X7,Q9Y4G8,Q06787,Q05086,Q9Y6W5,Q6IBS0,Q32P28,Q13177,Q96PU5,Q14651,Q9NUM4,P11233,Q9P2S5,O14976,Q14444,Q9P273,P43034,P46108,Q15375,P29317,Q16181,Q9UQB8,O14786,Q9H6U6 54 +Ceramide transport 0.9327443938173596 2.249303332563777 0.0244932039489369 1.0 0.2505696665258277 5 P07602 1 +Smooth muscle cell migration 0.8097374252922752 2.2476303045463464 0.0245997735231593 1.0 0.2506881360473489 10 O94813,Q07954,O14786 3 +Positive regulation of erk1 and erk2 cascade 0.6974244108869283 2.247327343749683 0.0246191146072647 1.0 0.2506881360473489 19 O14786,P05067,Q9Y4G8,Q13641 4 +Regulation of cell killing 0.8320502489883268 2.2453885210236417 0.0247432016809725 1.0 0.251562257584911 9 P04439,P01889,O15400,P11279,Q92692,P08238 6 +Regulation of glycoprotein metabolic process 0.8089229582978917 2.2442105032002733 0.0248188605711394 1.0 0.2519420753656719 10 Q9NQX7 1 +Positive regulation of binding 0.5574518239999757 2.2423086398125576 0.0249414317505205 1.0 0.2522479977779218 55 Q8TEY7,Q07954,P09429,P62913,O75503,Q13526,P26583,Q9Y4G8,Q06787,P05067,P49768,P62942,P16949,O14786,P05198 15 +Positive regulation of cell killing 0.8810818994121454 2.241977489289535 0.0249628272143536 1.0 0.2522479977779218 7 P11279,P01889,P04439,Q92692 4 +Vitamin transport 0.8311108354181422 2.2415647690911342 0.0249895150977157 1.0 0.2522479977779218 9 Q9NPF0,Q8WTV0,P33527,P04062 4 +Receptor recycling 0.8310619799319159 2.2413658621114325 0.0250023859153549 1.0 0.2522479977779218 9 P42892 1 +Regulation of lysosomal lumen ph 0.8551627695614668 2.238282345836565 0.0252026486350063 1.0 0.2528928822384155 8 O75503,P50897 2 +Xenobiotic transport 0.9295788467611376 2.23756435939905 0.025249477928992 1.0 0.2528928822384155 5 P08183,Q9NV96,P33527 3 +Macrophage activation 0.8798920572019939 2.2374125976560917 0.0252593859349796 1.0 0.2528928822384155 7 P01130,P05067 2 +Cellular response to inorganic substance 0.5799475871053208 2.235608734097223 0.0253774119747169 1.0 0.2528928822384155 42 Q92542,Q06787,Q9NP58,P05067,Q99538,O95831,P05198 7 +Antigen processing and presentation of peptide antigen via mhc class i 0.7697258265992248 2.2350025051851334 0.0254171842774746 1.0 0.2528928822384155 12 P04439,P01889,Q9UIQ6 3 +Neuron projection arborization 0.8790775813119471 2.2342864379113183 0.0254642321146323 1.0 0.2528928822384155 7 Q13641 1 +Cellular iron ion homeostasis 0.7230080132394037 2.233514433965719 0.0255150395560519 1.0 0.2528928822384155 16 P02786,Q15904,P02792 3 +Muscle cell migration 0.7542440405713041 2.2302580299844057 0.025730317751176 1.0 0.2535161321822133 13 O94813,Q07954,O14786 3 +Aminoglycan catabolic process 0.9848394768133172 2.230040997936621 0.0257447212371113 1.0 0.2535161321822133 4 P15586,P54802,P04066 3 +Glycosaminoglycan catabolic process 0.9848394768133172 2.230040997936621 0.0257447212371113 1.0 0.2535161321822133 4 P15586,P54802,P04066 3 +Negative regulation of cell activation 0.6777294525249395 2.2281419635359927 0.0258710497368148 1.0 0.2543793201326879 22 P01130,P09429,P10644,P22466 4 +Chemokine production 0.7818289273906656 2.226688524022843 0.0259680979372163 1.0 0.2546522698275656 11 P05067,P09429,P29317 3 +Positive regulation of protein binding 0.6515897508374502 2.220843013600236 0.0263615960860212 1.0 0.255066363522179 26 Q8TEY7,Q07954,P62913,Q13526,Q9Y4G8,P05067,Q96D46,P49768,P62942,O14786 10 +Lipoprotein catabolic process 0.9242612620719256 2.21781180915426 0.0265676665971308 1.0 0.255066363522179 5 P01130 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.7795143839066911 2.2166208707996886 0.0266490101467071 1.0 0.255066363522179 11 Q6YHK3,P62942,Q13526,Q92896 4 +Smad protein signal transduction 0.8249672219880809 2.2165152171900817 0.0266562368836436 1.0 0.255066363522179 9 Q9UIQ6,Q07954 2 +Organic hydroxy compound metabolic process 0.5118889257265655 2.215782643674739 0.0267063916921346 1.0 0.255066363522179 115 P34913,Q9BQE5,Q13510,P04062,O15118,P01130,P61916,Q14739,Q9UBM7,Q15126,Q9Y4G8,P05067,Q16850,P38571,Q15392,Q99538,Q8WTV0,Q9NX62 18 +Regulation of biological process involved in symbiotic interaction 0.8015065220864139 2.213005988629598 0.0268972327776444 1.0 0.255066363522179 10 Q9BTY2,P06756,Q92692 3 +Muscle cell cellular homeostasis 0.8733328663028763 2.212204964344038 0.0269525059974384 1.0 0.255066363522179 7 P13473 1 +Astrocyte development 0.873167598110841 2.2115688836590035 0.0269964674094436 1.0 0.255066363522179 7 P01130,P05067,Q07954,P11047 4 +Positive regulation of cell cell adhesion 0.6427238629198977 2.208853450242871 0.02718483588048 1.0 0.255825250961084 27 P09429,P30825,Q9Y624,Q08722,P02786,P04439 6 +Macromolecule depalmitoylation 0.9205457028966446 2.203985573245678 0.0275253586934984 1.0 0.2582907410639558 5 Q9UMR5 1 +Positive regulation of neuron projection development 0.6211750417846414 2.2034068957611193 0.0275660826061792 1.0 0.2583044036801237 32 Q14108,Q9NV96,Q14444,Q9P273,Q9Y4G8,P43034,Q9UQB8,Q32P28,Q13308,Q9NUM4,Q9H4M9 11 +Regulation of cation channel activity 0.6835406436730199 2.2011976408466283 0.0277220352482605 1.0 0.2593962274012203 20 P05556,P22466,P27105,P05067,P62942 5 +Lymphocyte mediated immunity 0.6205506212589142 2.199494800980756 0.0278427584107692 1.0 0.2601557739006249 32 P01889,O15400,P09429,P11279,Q92692,Q9UQ84,P02786,P04439,P53634,P13051 10 +Positive regulation of cellular protein catabolic process 0.5554695060118859 2.1977684638956907 0.0279656098417209 1.0 0.2609330234593477 52 P01130,P53634,Q07954 3 +Amyloid fibril formation 0.8200909639779694 2.196580242138663 0.0280504385859572 1.0 0.2613408551212878 9 P01130,P62942,P05067 3 +Glycerophospholipid catabolic process 0.8199600062820215 2.1960442202935537 0.0280887784388492 1.0 0.2613408551212878 9 P01130,Q8NCC3 2 +Anatomical structure maturation 0.6153244455061145 2.1905384355247612 0.0284852104803401 1.0 0.2618585654415086 33 Q9Y2W6,P04062,P22466,O75179,O75503,Q14118,P05067 7 +Regulation of cellular response to transforming growth factor beta stimulus 0.7138965695760302 2.188926493704721 0.0286021830845757 1.0 0.2618585654415086 16 Q6YHK3,O00560,Q13526,Q92896,P62942 5 +Regulation of signaling receptor activity 0.7048440966813908 2.18810535802271 0.0286619287196543 1.0 0.2618585654415086 17 P05556,P78536,P05067,O14786 4 +Regulation of leukocyte mediated cytotoxicity 0.8420863556469664 2.1864487314064416 0.0287827916745744 1.0 0.2625980632945223 8 P11279,P01889,P04439,Q92692 4 +Retinal ganglion cell axon guidance 0.9151305325955468 2.1837987974009314 0.028977036011254 1.0 0.2629116453545226 5 O94813,Q15375,O14786 3 +Aminoglycan biosynthetic process 0.8406538172908403 2.1807513842863218 0.0292018101719033 1.0 0.2633048695930974 8 O43505,P06865 2 +Phosphatidylcholine metabolic process 0.7032706848835447 2.18022519415493 0.0292407729473618 1.0 0.2633048695930974 17 P01130,Q8WTV0,Q8NCC3 3 +Regulation of pinocytosis 0.970763425706374 2.179109852435263 0.029323508523924 1.0 0.2633048695930974 4 Q06481 1 +Positive regulation of pinocytosis 0.970763425706374 2.179109852435263 0.029323508523924 1.0 0.2633048695930974 4 Q06481 1 +Cytokine production 0.4987893077043331 2.1735265524769676 0.0297407096040962 1.0 0.2651471210210945 104 Q06481,Q6GQQ9,P26583,P05067,Q8NCF5,Q9BUI4,Q13283,P78536,P04792,Q8IV08,P49768,P04439,Q08722,P06756,P01889,P04062,P09429,Q53EL6,Q9Y624,O60684,P29317,P23396 22 +Osteoclast differentiation 0.7555345869474623 2.171554468674761 0.0298892844947695 1.0 0.2653580842737708 12 Q6YHK3,Q15904,P02786 3 +Receptor internalization 0.6616390298811587 2.1715169642623047 0.0298921162126579 1.0 0.2653580842737708 23 P05556,Q13596,Q07954,P15311,O00560,O75955,Q06787,P62993,Q99700,P02786 10 +Sprouting angiogenesis 0.7102004638678852 2.1707708713658085 0.0299484968559835 1.0 0.2654347316103652 16 Q9Y6N7,O94813,O14786,P29317 4 +Pathway restricted smad protein phosphorylation 0.911099037477894 2.168742491295389 0.0301022394925829 1.0 0.266145875513724 5 O00560,Q13526,Q07954 3 +Macrophage differentiation 0.8373601996516995 2.1676382123139173 0.030186223973442 1.0 0.2662035989323139 8 P05067 1 +Cytosolic transport 0.5232808833897828 2.1670080826808005 0.0302342378210318 1.0 0.2662035989323139 70 Q99523,Q9Y3E7,O15260,Q9C0C9,Q9UMY4,Q9UEU0,P11279,O75503,Q8NBN3,Q14203,Q9BXI6,Q96ED9,P42566,Q4J6C6 14 +Single fertilization 0.6547401742537775 2.1660902637259016 0.0303042900625667 1.0 0.2662035989323139 24 Q08431,Q9GZP4,P07686 3 +Positive regulation of immune system process 0.5141602573769894 2.165412403765769 0.0303561169986816 1.0 0.2662035989323139 125 Q06481,O95219,P30825,P26583,Q9Y6K9,P05067,P02786,Q99538,Q9NPF0,P78536,O75179,Q9NR50,P49768,P53634,O94992,P11279,P04439,P01889,P09429,Q92692,Q08722,P23396 22 +Regulation of amyloid fibril formation 0.8786948564272824 2.164943012906094 0.0303920496804754 1.0 0.2662035989323139 6 P01130 1 +Negative regulation of chemotaxis 0.8784773703712265 2.164116243868098 0.0304554291430836 1.0 0.2664040065202183 6 O94813,O14786 2 +Organic acid transmembrane transport 0.6026236304567772 2.160565372380483 0.030728928709079 1.0 0.2684394329990997 35 P05556,P33527,Q6PCB8,P30825,P08183,Q96QD8,O43772,Q9H2J7,P08195 9 +Myeloid leukocyte activation 0.6473720925808109 2.1592349764629546 0.030831941832832 1.0 0.2689821132312585 25 O95219,P09429,P01130,Q92692,P05067,P53634 6 +T cell mediated cytotoxicity 0.8581184020070813 2.1534551522075622 0.031282925112527 1.0 0.2722075725427968 7 P04439,P01889,P53634,Q92692 4 +Natural killer cell mediated immunity 0.8093027853982848 2.152310418199581 0.0313729138284621 1.0 0.2726169447339819 9 P01889,P11279,P07437,Q92692,P04439 5 +Golgi to lysosome transport 0.906403324954687 2.1511759590352812 0.0314623138368728 1.0 0.2727432641477449 5 Q99523 1 +Motor neuron axon guidance 0.8573346852041264 2.1504183492175457 0.0315221382028485 1.0 0.2727432641477449 7 O94813,O14786,P84095 3 +Response to copper ion 0.8572586746347157 2.150123763240425 0.0315454264019514 1.0 0.2727432641477449 7 P05067 1 +Neuron maturation 0.8572329791354587 2.1500241757750516 0.0315533025260617 1.0 0.2727432641477449 7 O75503 1 +Regulation of synapse assembly 0.785829375565499 2.146664343948519 0.0318200133509165 1.0 0.2732079991141513 10 Q13641,P05067 2 +Cerebellar purkinje cell layer development 0.8560875467679774 2.145583727453962 0.0319062048556677 1.0 0.2732079991141513 7 P54802 1 +Nerve development 0.7854861070193235 2.1452059545147844 0.0319363837398947 1.0 0.2732079991141513 10 P42892,Q14118,O14786,O94898 4 +Regulation of natural killer cell mediated immunity 0.8733155589688146 2.144471785678058 0.0319951037680521 1.0 0.2733296007613597 6 P11279,P01889,P04439 3 +Cellular response to lipoprotein particle stimulus 0.9040540642975132 2.142375531285243 0.0321632752566554 1.0 0.2744098892844089 5 P05556,P01130,O15118 3 +Positive regulation of leukocyte cell cell adhesion 0.6616856607712702 2.1406827367492087 0.0322996315921977 1.0 0.2752162909500993 22 P09429,P30825,Q08722,P02786,P04439 5 +Regulation of protein catabolic process in the vacuole 0.9583236367163308 2.1338899488276346 0.0328517904441278 1.0 0.2780648003945022 4 P01130,Q07954 2 +Regulation of lysosomal protein catabolic process 0.9583236367163308 2.1338899488276346 0.0328517904441278 1.0 0.2780648003945022 4 P01130,Q07954 2 +Chloride transmembrane transport 0.870396755101017 2.133345016977485 0.0328964338963979 1.0 0.2780648003945022 6 P51790,Q9BXP2,Q9UHG3 3 +Neurotrophin signaling pathway 0.8283883348099512 2.131818068029993 0.0330218057118489 1.0 0.2780648003945022 8 Q99523,Q9Y4G8 2 +Cell activation 0.5213769753216214 2.1279345885904597 0.0333425073055608 1.0 0.2782107376507552 141 O15347,O95219,Q9BXW9,P01130,P30825,P78318,P05067,Q9Y4B6,P02786,P62942,P78310,Q9NPF0,P05556,P78536,Q07954,P22466,P53634,Q92542,P11279,P04439,P10644,P04062,P09429,Q9Y624,Q92692,Q96L92,Q08722,P13051,P23396 29 +Acute inflammatory response 0.9566863396731404 2.127923762126397 0.0333434050775727 1.0 0.2782107376507552 4 P02786,P42785 2 +Cell migration involved in sprouting angiogenesis 0.8029007071763115 2.1259314033537895 0.03350897163733 1.0 0.2782107376507552 9 O94813,O14786,Q9Y6N7 3 +Glucose import 0.8027948950582882 2.1254947442246093 0.0335453521587369 1.0 0.2782107376507552 9 Q99523,Q06481 2 +Neuropeptide signaling pathway 0.8995449958499998 2.125462215009634 0.0335480637018079 1.0 0.2782107376507552 5 Q99523,P22466 2 +Negative chemotaxis 0.9560047562425676 2.1254391399825523 0.0335499872842643 1.0 0.2782107376507552 4 O94813,Q15375,P06756 3 +Modified amino acid transport 0.8264922085044127 2.124229172595756 0.0336509849546482 1.0 0.2782107376507552 8 O43772,Q96QD8 2 +Oligosaccharide metabolic process 0.850239182604368 2.122877468424848 0.0337641209943933 1.0 0.2782107376507552 7 P17900,P10253,P06280 3 +Cytokine production involved in inflammatory response 0.8501013332202576 2.1223415805580013 0.0338090641295778 1.0 0.2782107376507552 7 Q8IV08,Q06481,Q53EL6 3 +Immune response regulating cell surface receptor signaling pathway 0.608277706823519 2.122233673074319 0.0338181201564702 1.0 0.2782107376507552 32 Q13144,P61088,Q06481,P17931,Q9NR50,Q92692,Q9Y6K9,Q13177,P49768,P04439,Q08722,P23396 12 +Negative regulation of peptidase activity 0.578811450184352 2.1203551420915563 0.0339761066488928 1.0 0.2782962864413269 39 Q6YHK3,Q9C0C9,Q07954,Q06481,P04080,P78318,P61201,Q96K76,P05067,Q92530,Q15392,Q04323 12 +Carboxylic acid transport 0.5689232918726704 2.119894649558318 0.0340149307234458 1.0 0.2782962864413269 41 P05556,Q6PCB8,P30825,Q96QD8,Q7L0J3,Q9H2J7,P07602,P08195 8 +Regulation of lymphocyte activation 0.5401627479811411 2.117588913329629 0.0342098979277822 1.0 0.2792712712011983 56 O15347,P09429,P22466,P30825,P11279,Q08722,P02786,P04439,Q9NPF0,P10644,P23396 11 +T cell migration 0.7788325649340981 2.1168894610425064 0.0342692303207283 1.0 0.2792712712011983 10 Q9Y624,O95747,P78536,P05067 4 +Membrane protein ectodomain proteolysis 0.7150159551986663 2.1148715670869143 0.0344408951163484 1.0 0.2793144667357559 14 Q9UKS6,P78536,Q92542,O94898,Q14118,P49768,Q8TCT8,O43847 8 +Entry of bacterium into host cell 0.8963510147655704 2.113464170336115 0.0345610585839792 1.0 0.2793144667357559 5 Q9BTY2 1 +Negative regulation of cytokine production 0.6195490584467348 2.111690323050754 0.0347130195771441 1.0 0.2793144667357559 28 P04062,Q06481,Q53EL6,P09429,P29317 5 +Regulation of stress activated protein kinase signaling cascade 0.6023753283268477 2.1079497512825847 0.0350353361224988 1.0 0.2805552388577165 33 Q96KB5,Q12959,P19525,P09429,P78318,Q53EL6,O00560,P43034,P05067,O75844,P29372,Q969S3,Q96J02,Q92905 14 +Epithelial cell proliferation 0.545849660121877 2.107186775881821 0.0351013927607024 1.0 0.2805552388577165 50 Q6YHK3,Q8N122,P78536,Q92542,P09429,P07942,P26583,Q86VI3,P11047,P29317,Q9Y6N7,Q8WTV0,O14786 13 +Intestinal absorption 0.7973867119445921 2.103147506629612 0.0354528772947539 1.0 0.2830206636467133 9 P01130,Q8WTV0 2 +Positive regulation of peptidyl serine phosphorylation 0.6960622967116777 2.100959204605519 0.0356445475289506 1.0 0.2842058589641664 16 P02786,Q8N122,P05067 3 +Negative regulation of neuron death 0.5467854883648099 2.0992911602803144 0.0357912421925505 1.0 0.2848439904257378 48 O75312,Q9UMX5,P04062,P08238,Q9Y6K9,P48681,P50897,P49768,Q99538,Q01105,O14786 11 +Amyloid precursor protein catabolic process 0.664329174850554 2.099064834990303 0.0358111857832297 1.0 0.2848439904257378 20 P78536,Q92542,Q13526,Q15392,P62942 5 +Brain morphogenesis 0.8435045770588369 2.096659845718284 0.036023697471248 1.0 0.2861882632438036 7 P49768,P19022,P04062,Q9BXW9 4 +Negative regulation of neuron differentiation 0.8431386940536074 2.095233318781002 0.0361502567684828 1.0 0.2862606951542636 7 O60271,P06730,P05067 3 +Astrocyte activation 0.9473131846373296 2.0937047516484015 0.0362862893964224 1.0 0.2862606951542636 4 P01130,P05067 2 +Platelet derived growth factor receptor signaling pathway 0.7381115140421646 2.093003487877279 0.0363488432020169 1.0 0.2862606951542636 12 Q07954,O14786 2 +Positive regulation of lipid transport 0.7949269309851289 2.092964569640627 0.0363523174586046 1.0 0.2862606951542636 9 Q07954,P22466 2 +Antigen processing and presentation of exogenous antigen 0.7948495075364725 2.092643863172461 0.036380957912582 1.0 0.2862606951542636 9 Q99538,Q9UIQ6 2 +Leukocyte chemotaxis 0.6102597264749876 2.0921335090791597 0.0364265743564427 1.0 0.2862771877140742 30 P09429,O94813,P35613,Q99538,P78310 5 +Modulation of excitatory postsynaptic potential 0.8904036402865272 2.0910845319298073 0.036520487042573 1.0 0.2863309964291264 5 P05067 1 +Regulation of cellular protein catabolic process 0.4809474618911883 2.090094221336735 0.036609336676862 1.0 0.2863309964291264 93 P04062,Q07954,P62913,P01130,Q9BW61,P60520,O00560,Q96KB5,P78559,Q06787,Q12834,Q9GZP4,Q92530,P49768,P08238,P53634,Q04323 17 +Chemical synaptic transmission postsynaptic 0.7237568631285816 2.0896298385773227 0.0366510640002013 1.0 0.2863309964291264 13 Q9UQB8,P05067 2 +Regulation of postsynaptic membrane potential 0.7237568631285816 2.0896298385773227 0.0366510640002013 1.0 0.2863309964291264 13 Q9UQB8,P05067 2 +Extracellular matrix disassembly 0.8177268467946568 2.089063346139714 0.0367020212902535 1.0 0.2863889632826666 8 Q07954 1 +Positive regulation by host of viral genome replication 0.858546058660244 2.0880317969932283 0.0367949665108806 1.0 0.2867740399390674 6 P27105 1 +Regulation of phospholipase a2 activity 0.9454933958309628 2.087048630715882 0.0368837388379343 1.0 0.2868238468860435 4 P50897 1 +Response to ph 0.8582756405057014 2.0869952483275975 0.0368885640719964 1.0 0.2868238468860435 6 Q99538,P04062 2 +Protein localization to plasma membrane 0.4853866651992842 2.085349564436678 0.0370375814137846 1.0 0.2870291845136651 83 P05556,P19022,O95429,Q07954,Q9UEU0,Q9Y624,Q13641,Q9Y4G8,P84095,Q15904,P35613,P29317,Q9H4M9,Q4J6C6 14 +Cell maturation 0.6344230300460707 2.0847272084216546 0.0370940694272932 1.0 0.2870291845136651 25 O75503,P05067 2 +Synaptic transmission gabaergic 0.94462393408178 2.0838670290033816 0.0371722641768679 1.0 0.2870291845136651 4 Q13641 1 +Regulation of t cell mediated cytotoxicity 0.8884540695304683 2.0837375280557877 0.0371840486270367 1.0 0.2870291845136651 5 P04439,P01889,Q92692 3 +Positive regulation of t cell mediated cytotoxicity 0.8884540695304683 2.0837375280557877 0.0371840486270367 1.0 0.2870291845136651 5 P04439,P01889,Q92692 3 +Axon extension 0.608842875936082 2.083338105588962 0.0372204156871627 1.0 0.2870291845136651 30 P05556,Q14247,Q9UJU6,O94813,P43034,P07900,P11047,A0MZ66,Q13740,P08238,O14786 11 +Amino acid transport 0.6339994967153129 2.082279148450332 0.0373169793767413 1.0 0.2874368739346661 25 P05556,P30825,Q96QD8,P49768,Q9H2J7,Q7L0J3,P08195 7 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.9432223543400706 2.078736319181473 0.037641592826239 1.0 0.2890606532383856 4 Q9P273,P78310,Q13740 3 +Amyloid precursor protein biosynthetic process 0.8870758199782192 2.078540334645472 0.0376596199187133 1.0 0.2890606532383856 5 Q9NQX7 1 +Positive regulation of protein containing complex disassembly 0.8385096312183398 2.0771661307493425 0.0377862286833012 1.0 0.2896944199053098 7 Q13137,P04062,P63241 3 +Fucose metabolic process 0.9425826849885476 2.076393911091793 0.037857533946481 1.0 0.289903211059316 4 Q9BTY2 1 +Negative regulation of defense response 0.6043845796853377 2.075856189813616 0.0379072536562985 1.0 0.2899464122687579 31 P01889,Q96KB5,P04062,P01130,P28070,O43657,Q9Y3Z3,Q7Z739,P04439,Q96J02 10 +Viral process 0.5216815848482431 2.0744830665191327 0.0380344698071999 1.0 0.2905815823365402 150 Q9Y3E7,P13591,P01130,Q9H1E3,Q14118,P11717,P02786,Q10472,P78310,Q14108,P05556,Q12899,O94992,O15118,P11279,Q8WTV0,P06756,Q9Y624,P27105,Q92692,P35613,O60684,P29317,Q13137,P08195,O14786 26 +Extracellular matrix assembly 0.8545392722869124 2.072661635237228 0.0382037805677111 1.0 0.2910709784706742 6 P07942,P11047 2 +Positive regulation of mapk cascade 0.5380829873324792 2.072413909162287 0.0382268573230004 1.0 0.2910709784706742 53 O60271,P19022,Q9UMX5,P09429,P19525,O00560,Q13641,Q9Y4G8,O14786,Q86VI3,P05067,Q04721,Q9Y6N7,P49768,Q969S3,P29372,P23396 17 +Neurotransmitter secretion 0.654381110495451 2.072087833154233 0.0382572507793375 1.0 0.2910709784706742 21 Q06787,P50897,P49768,Q7L0J3,Q4J6C6 5 +Detection of biotic stimulus 0.9413536469054522 2.071891895823689 0.0382755239247694 1.0 0.2910709784706742 4 P04439,Q8WTV0 2 +Aorta development 0.8129499632621389 2.069840937755551 0.038467242334383 1.0 0.2921618286588696 8 Q07954 1 +Regulation of nitric oxide synthase activity 0.8536919726456527 2.069408180062776 0.0385077995511158 1.0 0.2921618286588696 6 P06280 1 +Regulation of anion transport 0.7322938940883237 2.06661529756121 0.0387704181886725 1.0 0.2937795886292027 12 P05556,P08183,Q7L0J3 3 +Synapse assembly 0.6581139294587005 2.065756556380131 0.0388514720735906 1.0 0.2937795886292027 20 P19022,Q15375,P05067,Q13641 4 +Neuron projection extension 0.5661994118604933 2.0657191298096453 0.0388550079214664 1.0 0.2937795886292027 40 O60271,P05556,Q14247,Q9UJU6,O94813,Q9UIW2,P43034,P07900,P11047,A0MZ66,Q13740,Q96PU5,P08238,O14786 14 +Regulation of leukocyte chemotaxis 0.6711798554164321 2.062330387030349 0.0391762918920544 1.0 0.2955294129196489 18 Q99538,O94813,P09429 3 +Negative regulation of axonogenesis 0.810605306734375 2.0603910224535857 0.0393611744570441 1.0 0.2962446288082794 8 P49768,Q15375,O14786 3 +Regulation of phosphatidylcholine metabolic process 0.8819330008629227 2.05912395536329 0.0394823655449396 1.0 0.2968171434909865 5 P01130 1 +Transepithelial transport 0.8508197634018241 2.058371238607993 0.039554510466234 1.0 0.2970200569028396 6 P08183,P33527,P78310 3 +Protein kinase a signaling 0.7860209864871041 2.055997803757033 0.0397827278969389 1.0 0.2978074448986159 9 P22466 1 +Neuron differentiation 0.5588951868773208 2.05578180039865 0.0398035530423408 1.0 0.2978074448986159 240 O60271,P42892,Q9NV96,P13591,Q6PCB8,Q06481,O94898,Q9UJU6,O75503,Q13526,Q92859,P84095,Q14118,Q12834,P61201,P05067,P50897,Q9Y6N7,P16949,Q9H4M9,Q14108,P05556,Q8TEY7,Q15643,P54802,Q9UIW2,Q04721,Q13740,P49768,P08238,Q13308,P54920,Q9NQX7,P19022,P10586,O94813,Q8N0X7,Q13641,Q9Y4G8,Q06787,P11047,P06730,Q32P28,O60678,Q13177,Q96PU5,Q14651,P78559,Q9NUM4,O75312,P04062,P09429,P07942,Q14444,Q9P273,Q8N3F8,P43034,P35613,Q15375,P29317,Q9UQB8,O14786 62 +Mapk cascade 0.4888190873055194 2.0525548867256216 0.0401157666809586 1.0 0.2995249866371689 107 O60271,P23396,Q9UMX5,Q96KB5,P19525,P78318,P15311,O00560,Q13526,Q14118,P62993,P05067,Q9Y6N7,Q92905,Q99828,O75787,Q04721,P49768,P19022,Q12959,Q02750,Q13641,Q9Y4G8,Q86VI3,O00459,Q13177,Q99956,P29372,Q96J02,P06756,P04062,P09429,Q53EL6,O14744,P43034,P06493,Q15375,P29317,Q969S3,O14786 40 +Regulation of platelet derived growth factor receptor signaling pathway 0.8486786996780917 2.050135572729178 0.0403512029154682 1.0 0.3007224439277429 6 Q07954 1 +Regulation of transporter activity 0.5411805816579736 2.0499677657333244 0.0403675764652169 1.0 0.3007224439277429 47 P05556,P22466,P08183,Q06787,P27105,P05067,Q96PU5,P62942 8 +Regulation of anatomical structure size 0.4835960689687365 2.049484410348666 0.0404147707277953 1.0 0.3007334410038886 101 P42892,Q9UJU6,Q9HB40,P47756,A0MZ66,P62993,Q9BXP2,P08238,Q96B36,O15143,O95429,Q14247,Q12959,O94813,Q8N0X7,Q86VI3,P51790,Q14651,Q8N122,P43034,Q15375,Q9UQB8,O14786 23 +Positive regulation of cell adhesion 0.5224848392228245 2.0434819466796905 0.0410047527165304 1.0 0.3034527528245839 62 P09429,P30825,Q9Y624,Q14118,Q08722,P02786,P04439,O14786,P06756,P23396 10 +Ear development 0.6330283879486852 2.042883481981229 0.041063973848229 1.0 0.3034527528245839 24 P42892,Q15643,P54802,P43034,O95747,Q92688,Q13308 7 +Regulation of amyloid beta clearance 0.8466922066594295 2.0424881663677934 0.0411031320715573 1.0 0.3034527528245839 6 Q07954 1 +Regulation of cholesterol metabolic process 0.8294749606359697 2.0418022929564357 0.0411711467280855 1.0 0.3036141291225859 7 P01130,P34913 2 +Negative regulation of endocytosis 0.6836999785188305 2.039444763734226 0.0414056586902027 1.0 0.3046604282596796 16 Q9UKS6,O00560,Q6UWE0,Q9UNF0,P05067,P49768,P06756 7 +Detection of stimulus 0.6981021559546089 2.033912115270605 0.0419604572185599 1.0 0.3064297077046306 14 P04439,P01889,Q8WTV0 3 +Cell activation involved in immune response 0.5518310437012827 2.0335519221646177 0.0419967934732805 1.0 0.3064297077046306 42 P49768,Q07954,O95219,P11279,P09429,P05067,P02786,P13051 8 +Regulation of b cell proliferation 0.8272767713740209 2.0331778482313188 0.0420345582089334 1.0 0.3064297077046306 7 P02786 1 +Negative regulation of growth 0.5831960009157788 2.032851353676614 0.0420675430385844 1.0 0.3064297077046306 35 Q99538,O94813,Q15375,P50897 4 +Regulation of response to wounding 0.6741081324028251 2.0328221996342317 0.0420704894546701 1.0 0.3064297077046306 17 P05556,Q6YHK3,O94898 3 +Regulation of monooxygenase activity 0.7803579629578479 2.0324120679786484 0.0421119573981432 1.0 0.3064297077046306 9 P06280 1 +Response to wounding 0.478530242863814 2.020140356294831 0.0433688308400741 1.0 0.3128072031425523 83 Q9UQN3,Q9H444,Q9Y3E7,O94898,Q14118,P05556,P78536,P42785,P04792,O00299,Q04721,Q07812,Q13308,Q6YHK3,Q02750,P10586,P11047,Q8WTV0,P43121,Q13418,Q9Y624,P06493,P46108,P46060 24 +Cellular response to calcium ion 0.7081103408909799 2.016554345208925 0.0437420414976148 1.0 0.3146353981293339 13 Q99538 1 +Pinocytosis 0.7997042068438613 2.0163269993634545 0.043765793446084 1.0 0.3146353981293339 8 Q06481 1 +Response to nerve growth factor 0.6867763647792484 2.0155484693820074 0.0438472128606415 1.0 0.3148766006520742 15 Q99523,Q9Y4G8,P46108,P05067,Q9H4M9,Q99828 6 +Carbohydrate derivative transport 0.6525732913248738 2.0116565962059094 0.0442561489373203 1.0 0.3171208580715611 19 O00400,P07602,Q8WTV0,P61916 4 +Positive regulation of peptidase activity 0.5351637711736517 2.004217005666494 0.0450468196843765 1.0 0.3204268832766077 47 Q92542,P09429,P05067,Q92688,Q9Y6N7,Q99538,O95831,P23396 8 +Negative regulation of receptor mediated endocytosis 0.7183830562274124 2.0031950057437475 0.045156361526387 1.0 0.3204268832766077 12 O00560,P05067,P06756 3 +Cerebral cortex development 0.5958246807921154 2.0021019862362373 0.0452737639596767 1.0 0.3204268832766077 30 P19022,P07942,O94813,P43034,Q96QD8,P46108,O43776,Q9Y6N7,P49768,P11166 10 +Regulation of monocyte chemotaxis 0.8668672836608261 2.0020333663501195 0.0452811430733692 1.0 0.3204268832766077 5 Q99538,O94813 2 +Phosphatidylcholine catabolic process 0.9222478020381892 2.001673635291948 0.0453198437326598 1.0 0.3204268832766077 4 P01130,Q8NCC3 2 +T cell mediated immunity 0.7307376621946481 2.001661884849902 0.0453211083411715 1.0 0.3204268832766077 11 P01889,O15400,P09429,P36915,Q92692,P04439,P53634 7 +Regulation of vacuole organization 0.6913138980062918 2.0012072515188564 0.0453700598276654 1.0 0.3204268832766077 14 Q14108,Q9NUM4 2 +Regulation of phospholipase activity 0.7728228980919836 2.000934105829482 0.0453994915192761 1.0 0.3204268832766077 9 P50897 1 +Positive regulation of chemokine production 0.7952492760709375 1.9982590888220504 0.0456885784041258 1.0 0.3221216170871812 8 P05067,P09429 2 +Regulation of entry of bacterium into host cell 0.9210295203431702 1.9971815656415148 0.0458054628581208 1.0 0.3225999300650093 4 Q9BTY2 1 +Semaphorin plexin signaling pathway 0.7716634539587983 1.9960808657510911 0.0459251214012557 1.0 0.3230967364464813 9 P42892,O14786 2 +Ether metabolic process 0.7711122262373383 1.99377262075552 0.0461769089637407 1.0 0.3245210546618444 9 Q7L5N7,P34913,P07099 3 +Regulation of macrophage activation 0.8337719470521774 1.9926021166219676 0.0463050332388352 1.0 0.3250741821185255 6 P01130 1 +Activated t cell proliferation 0.9189760854699892 1.9896062077241456 0.0466343317933941 1.0 0.326590558196522 4 P10644,P09429 2 +Regulation of immune effector process 0.5323034106637407 1.9888330966463328 0.0467196283464468 1.0 0.326590558196522 48 P01889,O95219,Q06481,O75179,P11279,P09429,Q92692,Q08722,P02786,P04439 10 +Myeloid leukocyte migration 0.6056548595404957 1.9877874339845236 0.0468352040798896 1.0 0.3268462468041221 27 P09429,O94813,P84095,P35613,Q99538,P78310 6 +Chemical homeostasis 0.5362934344978157 1.9876033020364747 0.0468555808355559 1.0 0.3268462468041221 194 Q06481,P01130,O75503,P61916,Q9H1E3,Q92859,Q5BJF2,Q9BXP2,P05067,Q8NE01,P50897,P02786,P62942,P16949,Q9H4M9,P42785,Q93050,Q9HC07,Q15043,P34913,O15260,O15118,P02792,Q15904,P51790,P07686,O00459,Q7L0J3,Q96PU5,Q8WTV0,Q9NUM4,P06756,P04062,P09429 34 +Organic acid transport 0.5271598557432478 1.9867700258736871 0.0469478876925599 1.0 0.3271432258915884 53 P05556,P33527,Q6PCB8,P30825,P08183,Q96QD8,O43772,Q7L0J3,Q9H2J7,P08195 10 +Regulation of lymphocyte migration 0.7921690449554223 1.98574623087479 0.047061508844872 1.0 0.3272416545259707 8 O95747,P78536,P05067 3 +Negative regulation of smooth muscle cell migration 0.9177075746192505 1.9849240899818623 0.0471529177280198 1.0 0.3275310378193398 4 Q07954 1 +Positive regulation of protein catabolic process 0.4983100388213865 1.9835821548631325 0.0473024401872466 1.0 0.3280741266061822 72 Q9UKS6,P04062,Q07954,P01130,Q9BW61,Q12834,Q06787,P49768,P53634,Q96J02,O43847,Q96PU5 12 +Positive regulation of endothelial cell migration 0.6330744225441134 1.982434771245448 0.0474306011557432 1.0 0.3280741266061822 22 Q13685,P04792,P78536,P09429,Q9H6U6,Q99538,Q8WTV0,O14786 8 +Skin epidermis development 0.7001287547534838 1.979043558462036 0.0478111022747478 1.0 0.3289763920118109 13 Q6YHK3,P22466 2 +Regulation of vesicle mediated transport 0.501479802320856 1.97844724563926 0.0478782743360926 1.0 0.3290943454365905 134 Q9Y3E7,Q06481,O95219,O00560,P05067,P50897,Q9H4M9,Q4J6C6,Q07954,P49768,P11279,Q08431,Q06787,Q96PU5,Q8WTV0,P11233,P06756,Q9UMY4,P09429,Q08722,O14786 21 +Regulation of protein containing complex disassembly 0.5537218095413162 1.977408336439836 0.0479954924241321 1.0 0.3295556880646568 40 O15344,Q9NYL9,P47756,P48681,P58546,Q99828,Q66K74,P46821,Q9NRR5,P15170,P35611,P52907,P62495,P63241,Q6IBS0,P78559,P29372,P04062,O75844,Q13137,O75083 21 +Inner ear receptor cell development 0.7899211983485248 1.97660433026503 0.0480863723058901 1.0 0.329835408788473 8 P54802,Q15643,P43034 3 +Regulation of t cell migration 0.8292896707317774 1.9752367906407873 0.0482412826233775 1.0 0.3305532886422684 6 O95747,P78536,P05067 3 +Integrin mediated signaling pathway 0.645605507933381 1.9744529550753285 0.0483302617532204 1.0 0.3308183785771945 19 P05556,O14786,P06756 3 +Defense response to gram positive bacterium 0.8283488304060214 1.9715879502085472 0.0486566638709802 1.0 0.3324240882675539 6 P04439,P26583,P29317 3 +Lymphocyte activation 0.4772023994374708 1.9701531234537248 0.0488208240989782 1.0 0.3324240882675539 103 O15347,Q9BXW9,P30825,P78318,Q9Y4B6,P02786,P62942,P78310,Q9NPF0,P05556,P78536,P22466,Q92542,P11279,P04439,P10644,P04062,P09429,Q96L92,Q08722,P13051,P23396 22 +G protein coupled receptor signaling pathway 0.5279886437475932 1.969474649708588 0.0488986108492577 1.0 0.3324240882675539 50 P42892,Q99523,Q06481,P22466,P48960,P11717,P07602 7 +Basement membrane assembly 0.8578554968688152 1.967735991511464 0.0490984223646204 1.0 0.3324240882675539 5 P07942,P11047 2 +Aortic valve morphogenesis 0.8575221759797176 1.9664653396657037 0.0492448822598485 1.0 0.3324240882675539 5 O94813 1 +Determination of adult lifespan 0.8097617396127461 1.9641794550665608 0.0495092844970308 1.0 0.3324240882675539 7 P04062 1 +Bone morphogenesis 0.7639981843520661 1.963931117146151 0.0495380806693361 1.0 0.3324240882675539 9 Q9NX62,Q15643,O75844,Q92896 4 +Regulation of steroid biosynthetic process 0.7866327720852779 1.9632146149436465 0.0496212418640675 1.0 0.3324240882675539 8 Q13510 1 +Phagocytosis recognition 0.9118108938773684 1.9631350142152797 0.0496304879860174 1.0 0.3324240882675539 4 Q08431,Q5KU26 2 +Cellular response to starvation 0.5763602922664122 1.962737950450106 0.0496766310074499 1.0 0.3324240882675539 34 Q8TEY7,Q8N122,Q02487,P04062,P60520,P13473,Q96QD8,P11166 8 +Negative regulation of blood pressure 0.9109157835675504 1.9598239937732087 0.0500163657853209 1.0 0.3328195597770159 4 Q9HB40 1 +Deoxyribonucleoside triphosphate metabolic process 0.8086106976027928 1.9596278441525463 0.0500393044419988 1.0 0.3328195597770159 7 Q9H773 1 +Feeding behavior 0.7851688827018877 1.9572479690362576 0.0503183215482454 1.0 0.3343372920650086 8 P05067 1 +Regulation of microtubule based movement 0.9100618500178724 1.9566644423571813 0.0503869330417963 1.0 0.3344553436417115 4 P11279 1 +Sensory organ development 0.5023199966762671 1.955289216849842 0.0505489432250836 1.0 0.3348301965547092 68 P42892,Q15643,Q14651,P54802,Q9P273,P43034,Q14517,P11047,O95747,P48681,Q92688,Q04721,P29317,P49768,Q13308,O14786 16 +Regulation of response to biotic stimulus 0.4985606381707129 1.9531631867243748 0.050800261680898 1.0 0.33516963022763 70 Q06481,P26583,Q9BUI4,O75179,P08238,O94992,P11279,Q9Y3Z3,Q13177,P04439,Q15648,Q96J02,P01889,P09429,O43657,Q6UWE0,Q92692,O75844,Q7Z739 19 +Neutral lipid biosynthetic process 0.8064235166804863 1.9509731993973152 0.0510602339920795 1.0 0.3365473138275547 7 P01130,Q8NCC3 2 +Immune response regulating signaling pathway 0.515211177839322 1.948809496923096 0.0513181792028045 1.0 0.3375709827960484 59 Q13177,Q13144,P61088,Q06481,O75179,P09429,O43657,P17931,Q9NR50,Q92692,Q5KU26,Q9Y6K9,Q07812,P49768,P04439,Q08722,Q96J02,P23396 18 +Neutral amino acid transport 0.8223723957268856 1.9483789469190251 0.0513696370215566 1.0 0.337571900427372 6 Q9H2J7,Q96QD8 2 +Monocyte chemotaxis 0.7821976801874386 1.94512631808006 0.0517597770777036 1.0 0.3394574412932547 8 Q99538,O94813 2 +Positive regulation of immune effector process 0.5534313425144868 1.943371337297768 0.0519713078403394 1.0 0.3405052420057298 39 P01889,O95219,Q06481,O75179,P11279,Q92692,P02786,P04439 8 +Regulation of jnk cascade 0.6643586712806943 1.942326216893436 0.0520976211576291 1.0 0.3405341769361064 16 P09429,Q53EL6,O00560,P43034,P05067,Q969S3,Q96J02 7 +Regulation of lipid localization 0.6207953506119297 1.942050144476085 0.0521310301268864 1.0 0.3405341769361064 23 Q9NV96,O15260,Q07954,P22466,Q8WTV0,Q9H4M9,P06756 7 +Cartilage development 0.6479589795568941 1.9410601562588428 0.0522509811598397 1.0 0.3408293344281072 18 Q15643,Q15043,O75844,Q92896 4 +Positive regulation of immune response 0.4724888938332446 1.9399509164114264 0.0523856553100241 1.0 0.3408435614533519 82 O94992,P01889,P49768,Q06481,O95219,P11279,P09429,P26583,Q92692,Q9NR50,Q9Y6K9,Q08722,P02786,P04439,P23396 15 +Inorganic anion transmembrane transport 0.737238446394669 1.9377951583059163 0.0526482187119254 1.0 0.3420231322240407 10 P51790,Q9BXP2,Q9UHG3 3 +Neurotrophin trk receptor signaling pathway 0.8194652240907928 1.9370700999007564 0.0527367749954561 1.0 0.3421129249705232 6 Q99523 1 +Adaptive immune response 0.5284681194063596 1.9364015646864523 0.0528185380044294 1.0 0.3423057566434849 44 P01889,O15400,P78536,P09429,Q6GQQ9,Q92692,Q13740,P02786,P04439,P53634,P10321,P13051 12 +Deoxyribose phosphate catabolic process 0.8189767088219283 1.9351685658713655 0.0529696137676349 1.0 0.3423555423500025 6 Q9H773,P13051 2 +Negative regulation of cell projection organization 0.572124112249884 1.9347581538812764 0.0530199803835833 1.0 0.3423555423500025 34 Q9NQX7,O94898,O94813,Q8N0X7,Q9Y4G8,Q15375,P49768,O14786 8 +Memory 0.7157738600811953 1.9346612612183929 0.053031877090353 1.0 0.3423555423500025 11 P01130 1 +Lipid storage 0.6378306206043681 1.932753485159584 0.0532665729439125 1.0 0.3427946712315642 19 P17900,Q8WTV0,P07686,P06756 4 +Angiogenesis involved in wound healing 0.9035163925073924 1.932419114648298 0.0533077966487147 1.0 0.3427946712315642 4 P42785,P43121 2 +Positive chemotaxis 0.8181090822453342 1.931790488552129 0.0533853705345972 1.0 0.3427946712315642 6 P26583,P09429,O14786 3 +Antigen processing and presentation of exogenous peptide antigen 0.8179185312008939 1.9310484364464588 0.0534770627610274 1.0 0.3427946712315642 6 Q99538,Q9UIQ6 2 +Embryonic appendage morphogenesis 0.6754516578577181 1.9243159068672648 0.0543149979165689 1.0 0.3452019867586379 14 P42892,O95747,Q04721,P49768,Q15648,Q9NX62 6 +Pallium development 0.5414817882758709 1.9229552647965296 0.054485668263515 1.0 0.3456188291585364 41 P19022,Q13144,P07942,O94813,P43034,Q96QD8,P46108,O43776,P18887,Q9Y6N7,P49768,P11166 12 +Myotube differentiation 0.6677667795852434 1.9217001150230328 0.0546435027825764 1.0 0.3461454900373953 15 P05556,Q99523,Q8IV08 3 +Positive regulation of lymphocyte mediated immunity 0.6523901489310255 1.9213959303088093 0.0546818112282478 1.0 0.3461454900373953 17 P01889,P11279,Q92692,P02786,P04439 5 +Neuron projection regeneration 0.7003607144639874 1.9203621889388929 0.0548121660961116 1.0 0.3461454900373953 12 P10586,P11047,O94898 3 +Camera type eye morphogenesis 0.6745479182071521 1.9199154403972505 0.0548685812622526 1.0 0.3461454900373953 14 P54802,Q9P273,Q14517 3 +Regulation of lymphocyte mediated immunity 0.6266427869592939 1.9197650512666755 0.0548875832103228 1.0 0.3461454900373953 21 P01889,P09429,P11279,Q92692,P02786,P04439 6 +Export across plasma membrane 0.7758976210166444 1.9193737825315036 0.0549370464577441 1.0 0.3461454900373953 8 P08183 1 +Modulation by host of viral genome replication 0.7742000006774354 1.9124229019993635 0.0558219728071622 1.0 0.3504773445317647 8 Q9H1E3,P27105 2 +Regulation of hydrolase activity 0.5275209837539763 1.912355375048203 0.0558306276526312 1.0 0.3504773445317647 191 Q06481,P78318,Q13526,P26583,P67870,P84095,O00170,P05067,P50897,Q9Y6N7,Q9BXI6,Q99538,P07602,P62942,P16949,Q14108,Q99523,P05556,Q07954,Q0IIM8,Q92530,Q92688,Q15043,Q6YHK3,Q92542,Q9Y4G8,Q86VI3,Q15392,Q9NUM4,O95831,P09429,P04080,Q9Y624,Q15375,P29317,O43847,P23396 37 +Positive regulation of leukocyte chemotaxis 0.68596516176067 1.912095322660165 0.0558639686857969 1.0 0.3504773445317647 13 P28482,P78536,P09429,P63000,O95747,Q99538 6 +Multi multicellular organism process 0.5843092844449461 1.9118848918460016 0.0558909599291306 1.0 0.3504773445317647 29 Q9BQE5,Q9UIQ6,Q96QD8,P35613,P49459,O60684,P07686,P11166 8 +Positive regulation of b cell proliferation 0.8971618547066076 1.9088356551232772 0.0562832957150964 1.0 0.3519311019143581 4 P02786 1 +B cell proliferation 0.7304040014955526 1.908031176305406 0.0563871869261431 1.0 0.3522458837608451 10 P02786 1 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.5746615112226982 1.906997901316193 0.056520859261248 1.0 0.3523386085772104 32 P01889,O15400,P78536,P09429,Q92692,P02786,P04439,P53634,P13051 9 +Cellular defense response 0.8966597238137974 1.9069702308274057 0.0565244425498829 1.0 0.3523386085772104 4 P05556,Q08380 2 +Forebrain development 0.5030618285468115 1.9065489611280315 0.0565790197291415 1.0 0.3523386085772104 64 P19022,Q13144,P07942,P00492,O94813,Q9Y4G8,P43034,Q96QD8,P46108,O43776,P05067,Q15154,P18887,Q9Y6N7,P49768,O14786,P11166 17 +Response to insulin 0.5044147146121437 1.905436077185075 0.0567234093163979 1.0 0.3523386085772104 63 Q99523,Q06481,P22466,Q9H1E3,O00459,Q9UQB8,Q15043,P11166 8 +Response to manganese ion 0.8958152178874099 1.9038322632337916 0.0569320332059013 1.0 0.3529678741078407 4 P05067 1 +Epithelial cell development 0.529007241571058 1.902196556803863 0.0571454628141347 1.0 0.3534269104936592 43 P19022,Q9Y624,Q9Y4G8,Q14517,P29317 5 +Positive regulation of anion transport 0.7716639040335151 1.902029795249147 0.0571672594656815 1.0 0.3534269104936592 8 P05556,P08183 2 +Zymogen activation 0.7078095328564192 1.898803592465146 0.0575903046917649 1.0 0.3557080040022816 11 Q99538,Q15392 2 +Response to testosterone 0.7707113937043735 1.8981235327744477 0.0576798108404217 1.0 0.3559266376250414 8 P04062 1 +Substrate adhesion dependent cell spreading 0.6016384035117809 1.8931558541071327 0.0583371462015704 1.0 0.358972635840908 25 P07942,O14786,P06756 3 +Regulation of fibroblast migration 0.7468361129047354 1.8915499690015456 0.0585509672632724 1.0 0.3596338407073763 9 P05556,Q06481 2 +Cell adhesion mediated by integrin 0.7060321217875958 1.890782699285736 0.0586533575701522 1.0 0.3599083825526691 11 P05556,P78536,P46108,P29317,P06756 5 +Protein localization to cell periphery 0.4612054119838199 1.8864390540710652 0.0592358139680664 1.0 0.3617017723998699 94 P05556,P19022,O95429,Q15643,Q07954,Q9UEU0,Q9Y624,Q13641,Q9Y4G8,P84095,Q14118,Q15904,P35613,P29317,Q9H4M9,Q4J6C6 16 +Heart development 0.4592449520633804 1.8841444153735456 0.0595454437788278 1.0 0.3623403600158462 92 Q14126,P42892,P05556,O94992,Q15643,Q9BZH6,Q53EL6,O94813,P10253,O75844,Q9Y6N7,P49768,P62942,P78310,P10644,O14786 16 +Response to retinoic acid 0.6796164548369028 1.8819287096146464 0.0598456957659148 1.0 0.3634949092781049 13 P11717 1 +Iron ion transport 0.7034073485616179 1.8789256805447323 0.0602546417710356 1.0 0.3639434030165617 11 P02786,P02792 2 +Central nervous system neuron development 0.7032258096720024 1.8781050673119473 0.0603667932691367 1.0 0.3639434030165617 11 O94813,P00492,P43034,Q9Y4G8,P08238,O14786 6 +Neutrophil chemotaxis 0.6787876869654315 1.877983595347644 0.0603834092823762 1.0 0.3639434030165617 13 O94813,P78310 2 +Positive regulation of atp metabolic process 0.7879900051059044 1.8777345927099345 0.060417481923698 1.0 0.3639434030165617 7 P05067 1 +Positive regulation of nucleotide metabolic process 0.7879900051059044 1.8777345927099345 0.060417481923698 1.0 0.3639434030165617 7 P05067 1 +Neuron projection maintenance 0.8885255648038013 1.8767140607430817 0.0605572944569261 1.0 0.3643086454882268 4 P49768,P78559,P05067 3 +Animal organ morphogenesis 0.4771528780832011 1.874539493686185 0.0608561039158652 1.0 0.3652906624670748 115 Q9BXW9,Q14118,Q9Y6N7,P62942,Q15643,P54802,Q14517,P10253,P49768,Q9NX62,P19022,O94813,Q92896,P11047,P04062,Q53EL6,P07942,Q9P273,Q9ULC3,P35613,O75844,P29317,O14786 23 +Carbohydrate transmembrane transport 0.690448319267061 1.8744874781767784 0.0608632663520696 1.0 0.3652906624670748 12 Q99523,Q06481 2 +Positive regulation of peptidyl threonine phosphorylation 0.8032445345599245 1.8737465846090404 0.0609653618227756 1.0 0.3655698724432255 6 Q8N122,P05067 2 +Negative regulation of inflammatory response 0.6648925958227385 1.8727712894961577 0.0610999741947053 1.0 0.3660433791008851 14 P01130,P04062 2 +Rna splicing via endonucleolytic cleavage and ligation 0.8329329591767606 1.8723289754789885 0.0611611044392454 1.0 0.3660762010931364 5 Q5KU26 1 +Regulation of action potential 0.7013220939150284 1.8694954851647831 0.0615539111867446 1.0 0.3669104663584213 11 Q14126,Q02487,P04062 3 +Positive regulation of cell population proliferation 0.4862973788665256 1.8692431838551955 0.0615889887550236 1.0 0.3669104663584213 128 P30825,O00560,P26583,P84095,P02786,Q99538,Q9NPF0,P55209,Q9BSK2,P05556,P49459,Q86VI3,P11047,P04439,P06756,Q8N122,P09429,P07942,Q08722,O14786,P23396 21 +Collagen metabolic process 0.7012111628933516 1.8689935627594367 0.0616237099760956 1.0 0.3669104663584213 11 P05556,Q9UBG0,Q32P28 3 +Cardiac chamber development 0.6174955560272011 1.86895437143004 0.0616291627929881 1.0 0.3669104663584213 21 Q15643,O94813,Q04721,O75844,Q9Y6N7,P62942,Q13308,O14786 8 +Embryonic digit morphogenesis 0.7407664686040736 1.8658209860528483 0.0620664151842051 1.0 0.3688101888723593 9 P42892 1 +Basement membrane organization 0.7846228239861229 1.8642998361979144 0.0622796098194791 1.0 0.3694085712392503 7 P05556,P07942,P11047 3 +Negative regulation of protein containing complex assembly 0.5500954959137194 1.8619057146097604 0.0626163814125515 1.0 0.3694085712392503 37 P35080,Q15691,P04350,Q02790,P04062,P09429,O94813,P07737,P47756,Q6IBS0,Q9NZM5,P16949 12 +Regulation of phospholipid metabolic process 0.7196857387121403 1.861166944340395 0.0627206048421427 1.0 0.3694176636781351 10 P01130,Q8WTV0 2 +Positive regulation of anion transmembrane transport 0.8300128634594937 1.8610986859163812 0.0627302417647426 1.0 0.3694176636781351 5 P05556,P08183 2 +Positive regulation of protein catabolic process in the vacuole 0.989007724301842 1.8588919748613963 0.0630424518487777 1.0 0.3707412643973875 2 P01130 1 +Regulation of epidermal growth factor activated receptor activity 0.7827277752681049 1.8567312126620017 0.0633494044903852 1.0 0.3716359745426398 7 P78536,P05067 2 +Regulation of wnt signaling pathway 0.51418688546189 1.854961942544628 0.0636016614083279 1.0 0.372548289175406 49 P19022,Q07954,Q13526,Q9H2V7,Q13641,Q13308,P05067,P49768,Q13283 9 +Regulation of peptidyl threonine phosphorylation 0.7814593471657998 1.851662225222306 0.064074341582708 1.0 0.3742183710083138 7 Q8N122,P05067 2 +Amino acid transmembrane transport 0.6226717030012779 1.8508901230509311 0.0641853619705603 1.0 0.3742183710083138 19 P05556,P30825,Q96QD8,P49768,Q9H2J7,P08195 6 +Negative regulation of response to wounding 0.7590365271575853 1.8501214316000023 0.064296049651022 1.0 0.3742183710083138 8 Q6YHK3 1 +Transition metal ion transport 0.6532551567113786 1.849402896843336 0.0643996574643943 1.0 0.3742183710083138 15 Q07960,P02792,Q9HC07,Q9NP58,P02786,Q15043 6 +Molting cycle 0.6599961346877011 1.848772641711643 0.064490649374852 1.0 0.3742183710083138 14 Q6YHK3,P22466 2 +Negative regulation of cell growth 0.5685053745697515 1.8473635367515295 0.0646944701425042 1.0 0.3742183710083138 31 O94813,Q15375,P50897 3 +Cellular response to camp 0.8262026701064494 1.8464293980640183 0.064829881924006 1.0 0.3742183710083138 5 P05067 1 +Wound healing 0.4987000547761065 1.845392330836728 0.0649804879503679 1.0 0.3742183710083138 62 P05556,Q6YHK3,Q9Y3E7,P78536,P42785,Q9Y624,Q14118,Q8WTV0,P43121 9 +Interleukin 6 production 0.6592593171745569 1.84515609854514 0.0650148346452978 1.0 0.3742183710083138 14 P01889,P05067,P04062,P09429 4 +Organic anion transport 0.5072357221042174 1.8449852470752992 0.0650396847095484 1.0 0.3742183710083138 55 P05556,P33527,Q6PCB8,P30825,Q96QD8,O00400,Q7L0J3,Q9H2J7,P07602,P08195,P11166 11 +Negative regulation of stress activated protein kinase signaling cascade 0.7159532593636113 1.8447944472137336 0.0650674454944675 1.0 0.3742183710083138 10 Q12959,Q96KB5,Q53EL6,P78318,P15311,P43034,P51452,Q96J02 8 +Glutamate receptor signaling pathway 0.8799048751486288 1.84457242235088 0.0650997617230015 1.0 0.3742183710083138 4 Q06787,P05067,Q92542 3 +Striated muscle cell differentiation 0.5260199754828908 1.8439042036433395 0.0651971023787356 1.0 0.3742183710083138 42 P05556,Q99523,P19022,Q8IV08,P67809,O75844,P78310,P10644 8 +External encapsulating structure organization 0.5759622867755924 1.8435368859374557 0.0652506613382652 1.0 0.3742183710083138 28 P05556,Q07954,P07942,Q14118,P11047,P05067,Q9H9C1,P13674 8 +Tube morphogenesis 0.4755901222540309 1.8435268583396127 0.0652521239809267 1.0 0.3742183710083138 117 P01130,P67870,Q14118,Q9Y6N7,P05556,Q13685,P42785,Q07954,P49768,P19022,Q08431,O94813,Q9Y4G8,P43121,P06756,P35613,Q15375,P29317,O14786 19 +Regulation of hormone metabolic process 0.7950421979704881 1.8415832924586408 0.0655361267729555 1.0 0.3752464211699253 6 P22466 1 +Regulation of protein localization to plasma membrane 0.5704418533908193 1.841519432749156 0.0655454755129589 1.0 0.3752464211699253 30 P05556,O15400,Q12959,Q07954,Q9UEU0,P15311,P17931,P84095,P29317,Q14651,Q99828 11 +Regulation of cell adhesion 0.4632768219390233 1.8396054128203536 0.0658261891262426 1.0 0.3755049904757427 102 P23396,P09429,P30825,Q9P273,Q9Y624,Q15375,P29317,P02786,P04439,Q08722,O14786,P10644,P06756 13 +Regulation of axon guidance 0.8240266003508945 1.8380435577756271 0.0660559871281707 1.0 0.3755049904757427 5 O94813 1 +Regulation of microglial cell activation 0.9830659536541896 1.8354565191421148 0.0664380759399605 1.0 0.3755049904757427 2 P01130 1 +Fertilization 0.5604764354431397 1.835222061895702 0.0664727935395208 1.0 0.3755049904757427 33 O14967,Q08431,Q92692,Q9GZP4,P07686 5 +Neuron cellular homeostasis 0.7770086759434682 1.8338570851131049 0.0666752113249056 1.0 0.3755049904757427 7 Q14203,P78559,P51790 3 +Positive regulation of phagocytosis 0.7132505991155399 1.832922445559152 0.0668141052716215 1.0 0.3755049904757427 10 Q08431,Q06481 2 +Regulation of small molecule metabolic process 0.5034972878523776 1.8327046180678903 0.0668465101622217 1.0 0.3755049904757427 57 P34913,Q06481,P01130,Q9UBM7,P05067,O75844,Q9NPF0 7 +Collateral sprouting 0.8763201481954732 1.8311846914943832 0.0670729808608827 1.0 0.3764556895075826 4 Q15375,P05067 2 +Positive regulation of filopodium assembly 0.77560959828832 1.8282539209185489 0.0675114519071027 1.0 0.3776278321810559 7 P11233,Q06787,O14786 3 +Regulation of neurotransmitter levels 0.5654312343593171 1.827512827100826 0.0676226993697737 1.0 0.37792873105724 31 P05556,Q06787,P50897,Q8NCG7,P49768,Q7L0J3,Q4J6C6 7 +Neuronal stem cell population maintenance 0.8206172088481896 1.8248934232161147 0.0680171138882816 1.0 0.3791960613366539 5 P19022,Q9BXW9 2 +Cell projection organization 0.5448821989787801 1.8244257164551685 0.0680877371033692 1.0 0.3791960613366539 286 P42892,Q15691,Q06481,P00492,Q92859,P47756,A0MZ66,P05067,Q99538,Q8TC07,Q99828,Q14108,Q66K74,P51114,Q9NQX7,Q14247,Q02750,O94813,O75955,Q13641,P07900,Q6IBS0,Q9BYJ9,Q9NUM4,P04062,Q13418,P07942,O14976,Q9P273,O60749,Q15375,P29317,A6NIH7,Q16181,O14786,Q9NV96,P13591,Q6PCB8,Q13596,O94898,P15311,O14656,P84095,P07737,P46934,Q9Y6N7,Q4KMP7,P05556,Q15643,Q96TA1,Q9Y5K6,P50395,Q13740,O60493,P19022,Q02790,P63000,P10586,Q9Y4G8,P11047,Q05086,Q9Y6W5,Q32P28,Q9P289,Q9UBB6,Q96PU5,Q9Y366,Q9BZH6,P09429,Q14444,Q9ULC3,Q8N3F8,Q96PY6,Q92692,P35613,Q9UQB8,O00560,Q14118,Q9BXI6,P16949,Q9H4M9,Q8TEY7,P49768,Q13308,O95429,Q8N0X7,Q06787,P78559,P11233,O75312,Q9P2S5,P43034,Q9UNF0,Q14203,O60271,Q96J42,Q9UJU6,Q12834,P48681,Q9H223,Q9UIW2,Q04721,P08238,O60678,Q13177,Q14651,Q8IVD9,P46108,Q15154,Q9H6U6 110 +Regulation of cellular response to insulin stimulus 0.6673404328164002 1.823325572716444 0.0682540953712658 1.0 0.3791960613366539 13 Q06481 1 +Amyloid beta metabolic process 0.6479664446054788 1.8229158944955453 0.0683161302063486 1.0 0.3791960613366539 15 Q13526,Q92542 2 +Endosome to lysosome transport 0.60471946160596 1.822740097826689 0.068342764130177 1.0 0.3791960613366539 22 Q99523,Q9Y3E7,P20645,Q96L92,Q96ED9 5 +Anion transmembrane transport 0.5115520749322575 1.8224056992394584 0.06839345046425 1.0 0.3791960613366539 47 P05556,P33527,Q6PCB8,P51798,P30825,P08183,P51790,Q9BXP2,P49768,Q9UHG3,P08195 11 +Neurogenesis 0.5451557942669323 1.822382692646267 0.0683969388154186 1.0 0.3791960613366539 292 O60271,P42892,Q9NV96,P13591,Q6PCB8,Q06481,O94898,P01130,Q9UJU6,O75503,Q13526,P26583,Q92859,P84095,Q14118,Q12834,P61201,P05067,P50897,Q9Y6N7,Q8NCG7,P16949,P55209,Q9H4M9,Q14108,P05556,Q8TEY7,Q15643,Q07954,P54802,Q9UIW2,Q9NR50,Q9H0H5,Q04721,Q13740,P49768,P08238,Q13308,P54920,Q9NQX7,P19022,Q92542,P10586,O94813,Q8N0X7,Q13641,Q9Y4G8,Q06787,P11047,P06730,P07686,Q32P28,O60678,Q13177,Q96PU5,Q14651,P78559,Q15648,Q9NUM4,O75312,P04062,P09429,P07942,Q14444,Q9P273,Q8N3F8,P43034,P46108,P35613,Q15375,Q15154,Q15382,Q13885,P29317,Q9UQB8,O14786 76 +Syncytium formation 0.7898441022169065 1.8211520999693935 0.0685837394184436 1.0 0.3791960613366539 6 P05556,Q6YHK3 2 +Nucleoside triphosphate catabolic process 0.8735984987160438 1.8210116901856856 0.0686050798653674 1.0 0.3791960613366539 4 Q9H773 1 +Deoxyribonucleoside triphosphate catabolic process 0.8735984987160438 1.8210116901856856 0.0686050798653674 1.0 0.3791960613366539 4 Q9H773 1 +Regulation of potassium ion transmembrane transporter activity 0.6788388679715398 1.8204793395447427 0.0686860397622204 1.0 0.3791960613366539 12 P05556,Q12959,P22466,O95747,Q9Y376,Q96PU5 6 +Phospholipid dephosphorylation 0.7895623566699587 1.820043640186942 0.0687523593423005 1.0 0.3791960613366539 6 P34913 1 +Positive regulation of nervous system development 0.511898508323372 1.8197179825943095 0.0688019633719703 1.0 0.3791960613366539 46 Q02750,Q14444,Q9UJU6,O94813,Q9UIW2,Q13641,P43034,Q14118,A0MZ66,Q6IBS0,Q15382,Q9Y6N7,Q9UQB8,P55209,O14786 15 +Cerebral cortex cell migration 0.6901389128391693 1.818766470662472 0.068947065789604 1.0 0.3791960613366539 11 P07942,O94813,P49768,Q9Y6N7 4 +Negative regulation of protein polymerization 0.5835790444747921 1.8184041501215225 0.069002384527208 1.0 0.3791960613366539 26 P35080,Q15691,P04350,Q02790,Q9NYL9,P52907,O94813,P47756,P07737,P58546,Q6IBS0,P16949 12 +Mechanoreceptor differentiation 0.729470754314508 1.8177616389886544 0.0691005721459461 1.0 0.3794186674257375 9 P54802,Q15643,P43034 3 +T cell receptor signaling pathway 0.5940205640492979 1.8170526449155833 0.0692090527619542 1.0 0.3796973720334736 24 P28482,P49770,P61088,P15311,P17931,Q9NR50,Q92692,Q9Y6K9,P51452,Q13144,P49768,P04439,P23396 13 +Negative regulation of protein catabolic process 0.511409392362819 1.8159310310992984 0.0693809524854205 1.0 0.3803232545409135 46 Q96KB5,Q9UMY4,O94898,P62913,P60520,O00560,Q13526,P10619,Q92530,Q16850,P49768,P08238,P78559 13 +Positive regulation of axonogenesis 0.612010003880569 1.814642281340899 0.0695789003789228 1.0 0.3810907632744003 20 Q02750,Q9UJU6,O94813,Q9UIW2,P43034,A0MZ66,Q9Y6N7,O14786 8 +Positive regulation of nik nf kappab signaling 0.6772565006033667 1.8130950358570477 0.0698171646981129 1.0 0.3816806161495302 12 P05067,Q53EL6 2 +Regulation of cell shape 0.557095471282351 1.8128498234415429 0.0698549870018558 1.0 0.3816806161495302 33 P35579,Q12959,P63000,P15311,Q9UIW2,Q9Y624,P84095,Q14118,P46108,P07686,O75844,Q16181,Q9UQB8,Q9UEE9 14 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6387117342942186 1.8119220472828357 0.0699982422276761 1.0 0.3816806161495302 16 Q9C0C9,P78536,O00560,Q92859,P67870,Q9BRX2,Q04721,P08238 8 +O glycan processing 0.8711623871449503 1.8118997851938068 0.0700016826122209 1.0 0.3816806161495302 4 O43505 1 +Toxin transport 0.6523291860021782 1.8110742198666696 0.0701293635564119 1.0 0.3816806161495302 14 Q93050,O14786 2 +Positive regulation of lipid localization 0.6523175546836749 1.8110169173323043 0.0701382329858948 1.0 0.3816806161495302 14 Q8WTV0,Q07954,P22466 3 +Negative regulation of wnt signaling pathway 0.6026140637953303 1.8107704740032704 0.0701763885932673 1.0 0.3816806161495302 22 Q13641,Q07954 2 +Regulation of neutrophil migration 0.749395767319331 1.810313716632478 0.0702471511258846 1.0 0.3816806161495302 8 O94813 1 +Negative regulation of transport 0.4589954928251876 1.810186742644968 0.0702668327997995 1.0 0.3816806161495302 82 Q9Y3D6,Q07960,Q06481,O00560,P05067,P62942,Q13438,P49768,Q9UKS6,O95429,Q06787,O95747,Q9Y376,Q96PU5,P06756,Q9UMY4,P09429,Q6UWE0,Q9ULC3,Q9UNF0,Q16850,Q08722 22 +Regulation of nik nf kappab signaling 0.6229717873223213 1.808707813492532 0.0704964084688442 1.0 0.382611695468694 18 O43657,P05067,Q53EL6 3 +Eye morphogenesis 0.6226277550994985 1.8068723441702377 0.0707821855214358 1.0 0.3829502101519108 18 P54802,Q9P273,Q14517 3 +Oligosaccharide catabolic process 0.9753416518122404 1.8049575878783 0.0710813190900352 1.0 0.3833300417482895 2 P17900 1 +Regulation of glial cell differentiation 0.6754954407277769 1.8048704259905584 0.0710949606161315 1.0 0.3833300417482895 12 O14744,P01130,Q15382,Q14118 4 +Positive regulation of nervous system process 0.8686431951708826 1.8024710571023304 0.071471324380604 1.0 0.3844140406996018 4 P04062 1 +Interstrand cross link repair 0.8141917791844844 1.8000727862990318 0.0718491459990458 1.0 0.3858152509238557 5 Q9H1E3,Q9BXW9 2 +Regulation of myelination 0.6741536028133405 1.7985991716403509 0.072082108495268 1.0 0.3867504972935346 12 P53634,Q14118 2 +Regulation of triglyceride biosynthetic process 0.9732620320855624 1.7967403559848198 0.0723768490513092 1.0 0.3873839813340213 2 P01130 1 +Positive regulation of triglyceride biosynthetic process 0.9732620320855624 1.7967403559848198 0.0723768490513092 1.0 0.3873839813340213 2 P01130 1 +High density lipoprotein particle clearance 0.9732620320855624 1.7967403559848198 0.0723768490513092 1.0 0.3873839813340213 2 P01130 1 +Cellular response to mechanical stimulus 0.6615303650516682 1.7954663308737784 0.0725794324676136 1.0 0.388152444530051 13 P11166,Q9Y624,Q96QD8 3 +Regulation of lysosome organization 0.972667855020797 1.7943921286231654 0.0727506024063671 1.0 0.3886755247991748 2 Q14108 1 +Central nervous system neuron differentiation 0.6347915564381342 1.791829972812502 0.0731602060338381 1.0 0.3886755247991748 16 O94813,P00492,P43034,Q9Y4G8,P49768,P08238,O14786 7 +Semi lunar valve development 0.7823876912224943 1.791780597518699 0.0731681179953616 1.0 0.3886755247991748 6 O94813 1 +Endothelial cell chemotaxis 0.8655603855080419 1.7909245542752843 0.0733054027928803 1.0 0.3886755247991748 4 Q99538 1 +Regulation of potassium ion transport 0.6415739993368307 1.790803886902519 0.073324771313413 1.0 0.3886755247991748 15 P05556,Q12959,P22466,O95747,Q9Y376,Q96PU5 6 +Detection of other organism 0.9714795008912656 1.7896950879017843 0.0735029425113009 1.0 0.3886755247991748 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.9714795008912656 1.7896950879017843 0.0735029425113009 1.0 0.3886755247991748 2 P04439 1 +Cardiac septum development 0.6479348100624531 1.789401212089292 0.0735502242731387 1.0 0.3886755247991748 14 Q15643,O94813,Q9Y6N7,Q13308,O14786 5 +Regulation of lipoprotein metabolic process 0.8113963104530697 1.789259180359514 0.0735730847119877 1.0 0.3886755247991748 5 P06756 1 +Regulation of protein localization to membrane 0.5065334994062625 1.7888843085740571 0.0736334493740709 1.0 0.3886755247991748 48 P05556,Q9Y3D6,P19022,O15400,Q12959,Q07954,Q9UEU0,P15311,P17931,O14737,P27105,Q14118,P84095,P29317,Q14651,Q99828 16 +Telencephalon development 0.5084368180882864 1.787999827171998 0.0737760357111994 1.0 0.3886755247991748 45 P19022,Q13144,P07942,P00492,O94813,P43034,Q96QD8,P46108,O43776,P18887,Q9Y6N7,P49768,P11166 13 +Extrinsic apoptotic signaling pathway via death domain receptors 0.6339887133359897 1.7877100365977887 0.0738228016217519 1.0 0.3886755247991748 16 P17931,Q99523,Q9NR28,P26583 4 +Regulation of pattern recognition receptor signaling pathway 0.6066738995117289 1.785125769563853 0.0742409189136401 1.0 0.3888029154933401 20 O43657,Q06481,P09429 3 +Glycosylceramide catabolic process 0.970291146761736 1.7849972759685366 0.0742617587296892 1.0 0.3888029154933401 2 P06280 1 +Microglia differentiation 0.970291146761736 1.7849972759685366 0.0742617587296892 1.0 0.3888029154933401 2 P05067 1 +Glycosylceramide metabolic process 0.970291146761736 1.7849972759685366 0.0742617587296892 1.0 0.3888029154933401 2 P06280 1 +Hormone metabolic process 0.5636780835673062 1.7816978559461785 0.0747985167328399 1.0 0.3904957484671599 29 P42892,Q9HB40,O75844,P22466 4 +Cellular response to nitrogen compound 0.4845172686943285 1.7812210104594075 0.0748763525985019 1.0 0.3905557919742852 138 Q8N122,P33527,Q07954,Q06481,Q92542,O94813,Q9H1E3,Q9Y4G8,Q5KU26,P05067,O00459,P49768,Q99538,Q9UQB8,O95831,Q15043,Q9BSK2 17 +Negative regulation of cytoskeleton organization 0.5175222106174278 1.780596363435585 0.0749784142988068 1.0 0.3905557919742852 42 Q15691,O15344,Q9NYL9,P07737,P47756,P58546,P16949,Q99828,P04350,P46821,P60983,Q02790,P35611,P52907,O94813,Q9Y6W5,Q6IBS0,Q13177,P29372,P35080,Q9Y624 21 +Regulation of t cell receptor signaling pathway 0.7422078422437945 1.780536893862539 0.074988137011785 1.0 0.3905557919742852 8 P15311,P17931,Q92692,Q9Y6K9,P51452,P23396 6 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.6054244489350142 1.7782012143838275 0.075370813574807 1.0 0.3919282305889964 20 P07602,P48960 2 +L amino acid transport 0.6388338240131067 1.777006526403944 0.0755671660410435 1.0 0.3922841908401409 15 P05556,P30825,Q96QD8,P49768,P08195 5 +Cardiac conduction 0.6164840268163425 1.774035181202266 0.0760573311773282 1.0 0.3927590839915702 18 Q14126,Q02487,O75844 3 +Positive regulation of lymphocyte migration 0.8608759106574988 1.7733619459894052 0.0761687504323402 1.0 0.3927590839915702 4 P05067,P78536 2 +Positive regulation of t cell migration 0.8608759106574988 1.7733619459894052 0.0761687504323402 1.0 0.3927590839915702 4 P05067,P78536 2 +Amino acid betaine transport 0.9673202614379092 1.7732494527604774 0.0761873808411741 1.0 0.3927590839915702 2 O43772 1 +Renal system process 0.6376412851404438 1.7709958388026763 0.0765613936984459 1.0 0.3940695209298728 15 Q99538,P43121 2 +Positive regulation of long term synaptic potentiation 0.991323990335145 1.769244606041921 0.0768530632161663 1.0 0.3952614932259127 3 P05067 1 +Neural precursor cell proliferation 0.5637859842673278 1.7671702999968686 0.0771997120186211 1.0 0.3955597266237383 28 P19022,Q06481,P43034,Q9H0H5,O95456,P48681,Q8NCG7,P55209 8 +Cardiac muscle cell cardiac muscle cell adhesion 0.7761413020454091 1.767118681551907 0.077208354484036 1.0 0.3955597266237383 6 Q14126,Q02487 2 +Regulation of supramolecular fiber organization 0.4552326196649885 1.766953439130641 0.0772360262896219 1.0 0.3955597266237383 101 Q15691,P01130,Q9UJU6,P47756,P62993,P05067,P16949,Q99828,Q66K74,P04350,P49768,O15143,P60983,Q99471,O95429,Q14247,Q12959,O94813,Q13177,P78559,P29372,Q9Y624,Q08722,Q14203,Q9UQB8,O14786,P23396 27 +Cardiac ventricle development 0.6299074632061754 1.766739571562702 0.0772718529509735 1.0 0.3955597266237383 16 Q15643,O94813,O75844,Q9Y6N7,P62942 5 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.8582531785704595 1.763520174442405 0.0778127977388878 1.0 0.3961465170994983 4 P42892 1 +Regulation of protein binding 0.4971613862310047 1.7631591525252257 0.0778736509107078 1.0 0.3961465170994983 55 Q8TEY7,Q15691,Q07954,P62913,P10586,Q13526,Q9Y4G8,P46108,P48681,P05067,Q96D46,Q07812,P49768,P08238,P62942,P35269,O14786 17 +Head development 0.4983046501434178 1.7622912261743835 0.078020105517429 1.0 0.3961465170994983 163 O75503,Q5KU26,P05067,P50897,Q9Y6N7,P05556,P54802,Q92688,O94992,P19022,Q92542,O94813,Q9Y4G8,P11166,Q9BZH6,P04062,P07942,Q96QD8,Q8NB90,O95456,Q15375,Q9UQB8,O14786 23 +Camp mediated signaling 0.8576844178456079 1.761385079749515 0.0781732486192923 1.0 0.3961661243587864 4 P22466 1 +Regulation of rho protein signal transduction 0.6534431690352812 1.756559025553014 0.078993002225346 1.0 0.398780497327568 13 P05556,Q9Y624,O75955,P52565,P11274,Q9Y6N7,P16949,O14786 8 +Branched chain amino acid transport 0.9628639334521688 1.7556192517289193 0.0791534427684936 1.0 0.398780497327568 2 Q9H2J7 1 +Leucine transport 0.9628639334521688 1.7556192517289193 0.0791534427684936 1.0 0.398780497327568 2 Q9H2J7 1 +Alanine transport 0.9628639334521688 1.7556192517289193 0.0791534427684936 1.0 0.398780497327568 2 Q96QD8 1 +Amyloid beta clearance by cellular catabolic process 0.987511015040158 1.7555967106216448 0.0791572942950886 1.0 0.398780497327568 3 P01130 1 +Axonogenesis involved in innervation 0.9625668449197874 1.7544435576127688 0.0793545332856457 1.0 0.3989718689309415 2 P42892 1 +Regulation of retinal ganglion cell axon guidance 0.9625668449197866 1.7544435576127662 0.0793545332856462 1.0 0.3989718689309415 2 O94813 1 +Regulation of gtp binding 0.7570339920278601 1.7535912697149387 0.0795005680265046 1.0 0.3989718689309415 7 P16949,O75503 2 +Regulation of wound healing 0.6644254115834874 1.7530175375643138 0.0795989967986097 1.0 0.3989718689309415 12 Q6YHK3 1 +Regulation of innate immune response 0.5003856644306194 1.7524713852088367 0.079692786032844 1.0 0.3989718689309415 50 O94992,P04439,P01889,Q06481,P09429,P11279,Q15648,P26583,Q92692,Q9Y3Z3,Q13177,P08238,Q9BUI4,Q7Z739 14 +Aminophospholipid transport 0.961972667855022 1.752092042769014 0.0797579823113694 1.0 0.3989718689309415 2 Q14108 1 +Acute phase response 0.9616755793226396 1.7509162224524095 0.0799603419953953 1.0 0.3990389842361853 2 P02786 1 +Regulation of anion transmembrane transport 0.7562692948823013 1.7505071584053784 0.0800308400199019 1.0 0.3990389842361853 7 P05556,P08183 2 +Establishment of epithelial cell apical basal polarity 0.7717270280706237 1.7496597607408657 0.0801770410705207 1.0 0.3990389842361853 6 Q14517 1 +Monosaccharide metabolic process 0.4666305151208216 1.7481418830454067 0.0804394620976551 1.0 0.3990389842361853 75 P04066,Q92520,P10253,Q9BTY2,O00754,P16278,O75844,Q9Y2E5,Q15043 9 +Positive regulation of transporter activity 0.5997865385568862 1.7468933918323255 0.0806558323141724 1.0 0.3990389842361853 20 P22466 1 +Import across plasma membrane 0.5868656161674263 1.7468080403888862 0.0806706414206914 1.0 0.3990389842361853 23 P05556,P30825,Q9BXP2,P08195,Q15043,P11166 6 +Cellular carbohydrate catabolic process 0.6187099958924847 1.745871549923155 0.0808332745174122 1.0 0.3990389842361853 17 Q14108 1 +Negative regulation of leukocyte mediated immunity 0.7707623933843849 1.7458412129007423 0.0808385473632482 1.0 0.3990389842361853 6 P04439 1 +Negative regulation of cell killing 0.853448275862065 1.7454737169212644 0.0809024436369318 1.0 0.3990389842361853 4 P04439,P01889,P08238 3 +Positive regulation by host of viral process 0.7122916623523163 1.7442403579560382 0.0811171867151983 1.0 0.3990389842361853 9 P11717,P27105 2 +Heart morphogenesis 0.5525897268150988 1.7441308518863543 0.0811362754224109 1.0 0.3990389842361853 31 Q53EL6,O94813,P10253,O75844,Q9Y6N7,P62942,O14786 7 +Aromatic amino acid transport 0.9598930481283424 1.743860433052184 0.0811834294887439 1.0 0.3990389842361853 2 P08195 1 +Positive regulation of proteolysis 0.4504217129498075 1.7436702268970343 0.0812166098574986 1.0 0.3990389842361853 98 P04062,Q92542,P09429,Q9BW61,P05067,Q92688,Q9Y6N7,P49768,Q99538,P53634,Q9BXI6,O95831,O43847,P23396 14 +Amyloid beta formation 0.6507330029750021 1.7434873039207794 0.0812485300998198 1.0 0.3990389842361853 13 Q13526,Q92542 2 +Positive regulation of protein localization to membrane 0.5523430267304883 1.7425217690908492 0.0814171856541616 1.0 0.3990389842361853 31 P27105,P29317,Q07954,P84095 4 +Actin mediated cell contraction 0.6105674404618004 1.742306687714166 0.0814547938286107 1.0 0.3990389842361853 18 Q14126,Q02487,Q9UM22 3 +Positive regulation of pattern recognition receptor signaling pathway 0.732986989077288 1.742220010767166 0.0814699537593792 1.0 0.3990389842361853 8 O75179,P09429 2 +Microglial cell activation 0.9833580980683504 1.7407225077393074 0.0817322310003185 1.0 0.399728338676651 3 P01130,P05067 2 +Response to camp 0.692129275245803 1.7396672013725425 0.0819174717028872 1.0 0.4002523684732006 10 P05067,Q9Y4G8 2 +Regulation of cell morphogenesis 0.4743027141409217 1.7384375915087056 0.0821337377545239 1.0 0.4002990868500595 70 O60271,P15311,Q9UJU6,Q14118,P47756,P84095,O43707,Q5VSL9,P23528,Q99828,P35579,Q9UIW2,Q12959,P63000,P07686,Q96PU5,Q13418,Q14444,Q9Y624,P43034,P46108,O75844,Q16181,Q9UQB8,Q9UEE9,O14786 26 +Regulation of immune response 0.4740228720976856 1.738344434454855 0.0821501412395029 1.0 0.4002990868500595 129 Q06481,O95219,P17931,P26583,Q5KU26,Q9Y6K9,P02786,P62942,Q9BUI4,P61088,O75179,Q9NR50,Q07812,P49768,P08238,Q8TCT8,O94992,O15400,P11279,O96028,P28070,O75955,P07900,Q9Y3Z3,O00115,Q13177,P04439,Q15648,Q96J02,Q7Z739,P01889,Q13144,P09429,O43657,Q92692,P46108,Q08722,P23396 38 +Toll like receptor signaling pathway 0.649537554306509 1.737716159574915 0.0822608399068842 1.0 0.4002990868500595 13 Q06481 1 +Vasculogenesis 0.7105557340464259 1.7367830308538652 0.0824254753837032 1.0 0.4005154406289168 9 P06756,P29317 2 +Regulation of protein catabolic process 0.4773126607885706 1.7360051296303105 0.082562927560476 1.0 0.4005154406289168 134 Q96KB5,O94898,P01130,O00560,Q13526,Q12834,Q9GZP4,Q07954,P60520,P10619,Q92530,P49768,P08238,P53634,Q04323,Q9UKS6,Q9BW61,Q06787,Q96PU5,P78559,Q96J02,P04062,Q9UMY4,P62913,Q16850,O43847 26 +Substrate dependent cell migration cell extension 0.7975022301516304 1.7353823331306395 0.0826731072016087 1.0 0.4007543840620353 5 A0MZ66,O00560,Q14247,O14786 4 +Positive regulation of b cell activation 0.6715088536910903 1.7336907658617358 0.0829729658292168 1.0 0.4012285425662764 11 P02786 1 +Regulation of mitochondrial fusion 0.8500481899229558 1.7326912128665306 0.0831505671739496 1.0 0.4012285425662764 4 P02786 1 +Epidermis development 0.5005931313841762 1.7317964785660536 0.0833098053663743 1.0 0.4012285425662764 46 Q6YHK3,Q13510,P22466,P67809,O75844,P29317 6 +Regulation of t cell mediated immunity 0.7302647120696476 1.7308827842352883 0.0834726727614376 1.0 0.4012285425662764 8 P04439,P01889,P09429,Q92692 4 +Fc receptor mediated stimulatory signaling pathway 0.7668293465379259 1.7302599298306045 0.0835838452403998 1.0 0.4012285425662764 6 Q06481 1 +Negative regulation of developmental growth 0.6359272755056534 1.7299400113753085 0.0836409936658015 1.0 0.4012285425662764 14 Q15375,Q99538,Q8N0X7,O14786 4 +Regulation of heart contraction 0.5575540595487933 1.727844044302444 0.0840161885286567 1.0 0.4012285425662764 28 Q14126,P10253,Q02487,O75844 4 +Modulation by host of viral process 0.6590555129441082 1.7277710034213487 0.084029287956163 1.0 0.4012285425662764 12 P11717,P27105 2 +Regulation of keratinocyte proliferation 0.7659723900794886 1.7268624170127744 0.0841923755107751 1.0 0.4012285425662764 6 Q6YHK3,Q04721 2 +Keratinocyte proliferation 0.7659723900794886 1.7268624170127744 0.0841923755107751 1.0 0.4012285425662764 6 Q6YHK3,Q04721 2 +Axon midline choice point recognition 0.955436720142604 1.7262146956276228 0.0843087951952328 1.0 0.4012285425662764 2 P05067 1 +Axon choice point recognition 0.955436720142604 1.7262146956276228 0.0843087951952328 1.0 0.4012285425662764 2 P05067 1 +Olfactory bulb interneuron development 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Regulation of chemokine mediated signaling pathway 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Olfactory bulb interneuron differentiation 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Negative regulation of chemokine mediated signaling pathway 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Roundabout signaling pathway 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Cerebral cortex tangential migration 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O94813 1 +Outflow tract septum morphogenesis 0.9554367201426028 1.726214695627618 0.0843087951952337 1.0 0.4012285425662764 2 O14786 1 +Regulation of cell projection assembly 0.4944895035782172 1.7257424038917573 0.084393765731797 1.0 0.4012285425662764 53 Q9H6U6,P84095,P07737,P47756,Q9BXI6,Q8TC07,Q4KMP7,P50395,P51114,P63000,O94813,Q06787,Q9Y6W5,Q6IBS0,P11233,Q9P2S5,P29317,Q16181,O14786 19 +Positive regulation of signaling receptor activity 0.7499680886380344 1.725063043330618 0.0845161117702488 1.0 0.4012285425662764 7 P05556,O14786 2 +Regulation of extracellular matrix organization 0.765477618850872 1.7249004186674888 0.0845454201223123 1.0 0.4012285425662764 6 Q07954 1 +Multicellular organism aging 0.669512019028327 1.7245312629997605 0.0846119801832205 1.0 0.4012285425662764 11 P04062 1 +Postsynapse organization 0.5226917593564885 1.7242622757396189 0.084660506223295 1.0 0.4012285425662764 39 P19022,Q14247,Q14444,Q9UJU6,P43034,Q15375,O60678,Q99538,Q9UQB8,O14786 10 +Fibroblast migration 0.6213244789518649 1.7224935762467315 0.0849801454591836 1.0 0.4018687252555787 16 P05556,Q06481 2 +Olfactory lobe development 0.8471641770580312 1.7218410589019282 0.085098314514139 1.0 0.4021384431566141 4 O94813 1 +Regulation of triglyceride metabolic process 0.8470517503908135 1.7214179473621525 0.0851750098135168 1.0 0.4021798341210374 4 P01130 1 +Positive regulation of cell junction assembly 0.6459580277685886 1.720416627712212 0.0853567366448797 1.0 0.4024921961648881 13 Q13641,P29317 2 +Circulatory system development 0.4969027601260395 1.7190269417946522 0.0856094662943929 1.0 0.4027460549678622 168 Q14126,P42892,P01130,Q14118,Q9Y6N7,P62942,P78310,P05556,Q13685,Q15643,P42785,Q07954,O75179,P10253,Q92688,P49768,O94992,P19022,Q08431,O94813,Q9Y4G8,P43121,P06756,P10644,Q9BZH6,Q53EL6,P35613,O75844,P29317,O14786 30 +Tor signaling 0.5906303618094587 1.7180994147532866 0.0857784835759936 1.0 0.4027460549678622 21 Q8N122,P04062,Q15382,Q6PKG0,O75844,Q96B36,Q96A49 7 +Cell substrate adhesion 0.4873274139923172 1.7179206169128454 0.08581109573607 1.0 0.4027460549678622 59 P05556,Q14247,Q13418,P07942,Q9H2G2,Q9H6U6,Q9UM22,Q14118,P11047,P46108,P42771,P11274,O14786,P06756,Q99828 15 +Stress activated protein kinase signaling cascade 0.5174948234020723 1.7160208152269978 0.086158232732429 1.0 0.403720800838057 40 Q96KB5,Q12959,P19525,Q02750,P78318,P09429,O00560,Q53EL6,P43034,P05067,O75844,P29372,Q99956,Q969S3,Q96J02,Q92905 16 +Multicellular organismal signaling 0.5719215748599301 1.715926436805653 0.0861755073523038 1.0 0.403720800838057 25 Q14126,Q02487,P04062,Q06787,O75844,P78310 6 +Germ cell migration 0.9527629233511584 1.7156231888251643 0.0862310314955108 1.0 0.403720800838057 2 P78310 1 +Polarized epithelial cell differentiation 0.7263642877063579 1.7146196136513698 0.0864149903462623 1.0 0.4040069697922626 8 Q14517 1 +Appendage morphogenesis 0.612546664855903 1.7134039477940908 0.0866382505246938 1.0 0.4042286217500202 17 P42892,O95747,Q04721,P49768,Q15648,Q9NX62 6 +Ganglioside catabolic process 0.975631500742942 1.7130235511499157 0.0867082069457705 1.0 0.4042286217500202 3 P17900,P06865 2 +Ganglioside metabolic process 0.975631500742942 1.7130235511499157 0.0867082069457705 1.0 0.4042286217500202 3 P17900,P06865 2 +Endocytic recycling 0.5660039442716969 1.7114049763388903 0.0870063791870696 1.0 0.4050938529188416 26 Q9UMY4,O95219,Q07960,Q8N3F8,Q15904,Q96L92,P42566,Q9H223,Q9H4M9 9 +Positive regulation of epithelial cell migration 0.5473443551083915 1.7098602399786835 0.0872917203173802 1.0 0.4052257842256365 31 Q13685,P09429,Q99538,Q8WTV0,O14786 5 +Grooming behavior 0.8438415742829531 1.709332165750753 0.0873894383328937 1.0 0.4053026351416895 4 P07741,P50897 2 +Alcohol biosynthetic process 0.5282015112466159 1.7091049820755235 0.087431504905147 1.0 0.4053026351416895 37 Q13510,P04062,Q14739,Q9UBM7,Q16850,Q15392 6 +Epoxide metabolic process 0.950980392156864 1.7085605891492237 0.0875323741632034 1.0 0.4053819490321871 2 P34913 1 +Endothelial cell proliferation 0.5889081184088928 1.708347576647848 0.0875718682843931 1.0 0.4053819490321871 21 Q8N122,P09429,P26583,P29317,Q8WTV0,O14786 6 +Formation of primary germ layer 0.5964721547168882 1.7076924092850645 0.0876934313579682 1.0 0.4056592063802497 19 P05556,P07942,P06756,P29317 4 +Pyrimidine containing compound catabolic process 0.7606345631486193 1.705679564098268 0.0880677565652039 1.0 0.4061070394259931 6 Q9H773 1 +Regulation of transmembrane transport 0.4620146200766142 1.7053365727457148 0.0881316703464203 1.0 0.4061070394259931 75 P05556,Q06481,P22466,P08183,Q06787,P27105,P05067,O75844,P49768,P62942,Q96PU5 11 +Microtubule anchoring at microtubule organizing center 0.8424760220884284 1.7041885042620148 0.0883458761657944 1.0 0.4061070394259931 4 Q8TD16,Q14203 2 +Regulation of peptidyl serine phosphorylation 0.5839120734813714 1.7037814058764555 0.0884219330233826 1.0 0.4061728180361808 22 P02786,Q8N122,P05067 3 +Interferon gamma production 0.7438499581016514 1.70030684466043 0.0890732236545592 1.0 0.4071923230605333 7 P04439,P09429 2 +Regulation of multicellular organism growth 0.6236295699531053 1.7001047955054052 0.0891112154316802 1.0 0.4071923230605333 15 Q99538,P05067 2 +Detection of external biotic stimulus 0.9717682020802376 1.6991624711612954 0.0892885753319694 1.0 0.4071923230605333 3 P04439,Q8WTV0 2 +Membrane raft organization 0.701809251117183 1.6991331651632184 0.0892940957257844 1.0 0.4071923230605333 9 P50897 1 +Deoxyribose phosphate metabolic process 0.6413639282456861 1.6981723823497563 0.0894752314268216 1.0 0.4075956179540395 13 Q9H773,P13051 2 +Heart valve morphogenesis 0.7431165664714283 1.6973359421151033 0.089633165734992 1.0 0.4077503210268171 7 O94813 1 +Amino acid import across plasma membrane 0.7219617250277321 1.6962356490694608 0.0898412617434887 1.0 0.4081732483862496 8 P05556,P30825,P08195 3 +Lipoprotein localization 0.7873301545643004 1.6958061549692716 0.0899225964822723 1.0 0.4082200411734901 5 A6NIH7,Q07954 2 +Negative regulation of immune effector process 0.682062201015171 1.694931680466138 0.0900883818459101 1.0 0.408533802451548 10 P01889,P17931,P46108,Q08722,P04439 5 +Pyrimidine deoxyribonucleotide metabolic process 0.7578694289551507 1.694692693972386 0.0901337323601418 1.0 0.408533802451548 6 Q9H773 1 +Regulation of binding 0.4483750241046627 1.68898800943928 0.091221727814023 1.0 0.4112723121291496 102 O75503,Q9H1E3,Q13526,P26583,P67870,P05067,P48681,P62942,P16949,Q8TEY7,Q07954,P49768,P08238,P35269,P10586,Q9Y4G8,Q06787,P05198,P09429,P62913,P46108,O14981,Q96D46,O75844,O14786 25 +Regulation of fc receptor mediated stimulatory signaling pathway 0.8382758597953622 1.6883581914783954 0.0913424909513684 1.0 0.4112723121291496 4 Q06481 1 +Leukocyte mediated immunity 0.4913700807816714 1.6867425089644672 0.0916528744147493 1.0 0.4112723121291496 51 P01889,O15400,P78536,O95219,P09429,P11279,Q92692,Q9UQ84,P02786,P04439,P53634,P13051 12 +Reproductive behavior 0.968248225223138 1.6865268461216807 0.0916943687392286 1.0 0.4112723121291496 3 P05067 1 +Mating 0.968248225223138 1.6865268461216807 0.0916943687392286 1.0 0.4112723121291496 3 P05067 1 +Mating behavior 0.968248225223138 1.6865268461216807 0.0916943687392286 1.0 0.4112723121291496 3 P05067 1 +Keratan sulfate metabolic process 0.9682020802377416 1.6863611610104137 0.0917262574173105 1.0 0.4112723121291496 3 P15586,P16278 2 +Protein localization to endosome 0.6501812671300823 1.6859183867324383 0.0918115199489066 1.0 0.4112723121291496 12 Q9NV96,Q8N3F8,O14786 3 +Small gtpase mediated signal transduction 0.4494763288699743 1.6834699782108784 0.0922841464185324 1.0 0.4112723121291496 104 Q07960,Q9UJU6,O00560,P84095,P62993,A0MZ66,P42771,Q9Y6N7,O60763,P16949,Q13283,Q9Y2I1,P23528,P05556,P80303,Q86X10,Q9Y5K6,Q96T51,Q9H0H5,P50395,Q04721,Q02818,Q15555,P63000,O94813,Q14974,O75955,Q9Y4G8,Q86VI3,P06400,P52565,Q9Y6W5,Q15392,P11233,P06756,Q9Y624,P36405,P46108,Q15382,P11274,Q96HP0,O14786 42 +Regulation of deoxyribonuclease activity 0.7841410364255941 1.6833765275702297 0.0923022242266149 1.0 0.4112723121291496 5 P09429 1 +Vitamin transmembrane transport 0.7549131212206096 1.6829361488432049 0.0923874527477282 1.0 0.4112723121291496 6 Q8WTV0 1 +Retrograde transport endosome to golgi 0.5128122969990792 1.6816998192232653 0.0926270631186163 1.0 0.4112723121291496 40 O15260,Q9C0C9,Q9UMY4,Q9UEU0,O75503,Q8NBN3,Q9BXI6,Q14203,Q4J6C6 9 +Positive regulation of leukocyte mediated immunity 0.5756837883374216 1.68157287818862 0.0926516935057122 1.0 0.4112723121291496 23 P02786,P04439,P11279 3 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.9438502673796796 1.6802984859826784 0.0928992554993397 1.0 0.4120642634353721 2 O00170 1 +Regulation of lipid metabolic process 0.4858776164783489 1.6787896681055248 0.0931930429142067 1.0 0.4129989656417417 56 P34913,Q13510,Q06481,P22466,P01130,P61916,O75844,P07602,Q8WTV0 9 +Salivary gland development 0.8356811095850035 1.6785716661514904 0.0932355524442059 1.0 0.4129989656417417 4 Q14118,O14786 2 +Forebrain cell migration 0.6485025144351618 1.6779831323073175 0.0933503919547817 1.0 0.4131116870187521 12 P07942,O94813,P49768,Q9Y6N7 4 +Protein localization to synapse 0.6483649390763778 1.6773325811216089 0.0934774648269916 1.0 0.4132357282472787 12 P04792,Q9UQB8,Q14118,P78559,Q14168 5 +Golgi to endosome transport 0.7528944998441186 1.6749026643205838 0.0939533308010056 1.0 0.413268741027442 6 Q99523 1 +Fc receptor signaling pathway 0.737567544240836 1.6748346900292004 0.0939666705159345 1.0 0.413268741027442 7 Q06481 1 +Xenobiotic transport across blood brain barrier 0.9423648247177676 1.6744083867741713 0.0940503656610034 1.0 0.413268741027442 2 P08183 1 +Sphingolipid translocation 0.9423648247177676 1.6744083867741713 0.0940503656610034 1.0 0.413268741027442 2 P08183 1 +Cobalamin transport 0.9423648247177676 1.6744083867741713 0.0940503656610034 1.0 0.413268741027442 2 Q9NPF0 1 +Peptidyl threonine modification 0.5442957907079273 1.6731270560814562 0.0943022862710882 1.0 0.4137233465151997 30 Q8N122,P67870,P05067,Q9Y4B6,Q10472 5 +Visual behavior 0.7368692142363946 1.6720001613403548 0.0945242902582998 1.0 0.4137233465151997 7 P05067 1 +Multicellular organismal homeostasis 0.4727947625293498 1.6708036449121528 0.0947604683699905 1.0 0.4137233465151997 66 P05556,O14773,Q9UIQ6,Q06481,P42785,P04062,Q9Y624,P16949,P11047,P51790,P38571,P02786,P78310,O43847,P11166 15 +Filopodium assembly 0.623974673463797 1.6704105678730723 0.0948381602096191 1.0 0.4137233465151997 14 Q9H6U6,Q06787,P47756,P51114,P11233,O14786 6 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.963744427934621 1.67035123065311 0.0948498926681926 1.0 0.4137233465151997 3 P04439,P01889 2 +Granulocyte chemotaxis 0.611229087776368 1.6702053374800665 0.0948787443572736 1.0 0.4137233465151997 16 P28482,P63000,O94813,P17931,P35613,P78310 6 +Pattern recognition receptor signaling pathway 0.5438173596320124 1.670018200086134 0.0949157627564409 1.0 0.4137233465151997 30 Q5KU26,O43657,Q06481,P09429 4 +Regulation of filopodium assembly 0.6354194272978705 1.6693216889438518 0.0950536441174145 1.0 0.413807326938685 13 Q06787,P47756,O14786,P11233,Q9H6U6 5 +Regulation of cell size 0.4934908980646703 1.6677629968531469 0.0953627841635997 1.0 0.4144039843528607 44 Q8N122,Q14247,Q9UJU6,Q8N0X7,P43034,Q86VI3,A0MZ66,P51790,Q9BXP2,Q15375,P08238,Q96B36,O14786 13 +Positive regulation of antigen receptor mediated signaling pathway 0.8327610404924131 1.667551951382933 0.0954047032620803 1.0 0.4144039843528607 4 Q92692,P23396 2 +Positive regulation of t cell receptor signaling pathway 0.8327610404924131 1.667551951382933 0.0954047032620803 1.0 0.4144039843528607 4 Q92692,P23396 2 +Positive regulation of jnk cascade 0.715060357181428 1.6673607514355235 0.0954426932646068 1.0 0.4144039843528607 8 P05067,P09429 2 +Fatty acid derivative biosynthetic process 0.6103009033639524 1.665384815953015 0.095836006777475 1.0 0.4152893627023919 16 Q9UMR5,P50897 2 +Regulation of dendrite development 0.5680069885543905 1.6633258618680862 0.0962472245852386 1.0 0.4165225285011181 24 Q14444,Q9UJU6,Q9Y4G8,Q12834,P43034,Q96PU5,Q9UQB8,Q9NUM4 8 +Regulation of ion transport 0.4327400458442611 1.660581336582592 0.0967975598795485 1.0 0.4179712186043346 87 P05556,P49768,O95219,P22466,P08183,P27105,Q06787,P05067,O75844,Q7L0J3,P62942,Q96PU5 12 +Response to epidermal growth factor 0.6158020308977671 1.660291295245989 0.0968558660383003 1.0 0.4179712186043346 15 O75312,O95429,P28482,Q06124,P46940,P51452,Q15648,Q9UQB8,P19338,Q96A49 10 +Ventricular septum development 0.6927520785014989 1.6600153629150138 0.0969113619731949 1.0 0.4179712186043346 9 O94813,Q15643,Q9Y6N7 3 +Sterol import 0.9607514390639668 1.6595968187697856 0.0969955887512081 1.0 0.4179712186043346 3 P01130 1 +Dendrite arborization 0.9607083537649828 1.6594419768743491 0.0970267635768955 1.0 0.4179712186043346 3 Q13641 1 +Innervation 0.960475482912333 1.6586050616803685 0.0971954011583342 1.0 0.4182412858095299 3 P42892,O14786 2 +Negative regulation of lymphocyte activation 0.5948777498963945 1.6576788888059213 0.0973822971394815 1.0 0.4184067606685235 18 O15347,P09429,P22466,P17931,Q96J02,P10644 6 +Lens development in camera type eye 0.6916525511532037 1.6552577127685288 0.0978722328230774 1.0 0.4197426458485329 9 Q14517 1 +Retina homeostasis 0.8293471784203548 1.6546606678712488 0.0979933497028326 1.0 0.4197426458485329 4 P51790,P11166 2 +Cellular extravasation 0.7117221221090284 1.653369545726698 0.0982556769553855 1.0 0.4197426458485329 8 P05556,Q9Y624,P46108,P11274,Q08722 5 +Negative regulation of rho protein signal transduction 0.8289438847576189 1.6531372025696491 0.0983029434032225 1.0 0.4197426458485329 4 P05556 1 +Cyclic nucleotide mediated signaling 0.7762019748428476 1.6523907545866106 0.0984549190419601 1.0 0.4197426458485329 5 P22466 1 +Response to peptide hormone 0.4336832122037317 1.6521493730844952 0.0985041040640377 1.0 0.4197426458485329 89 Q99523,P09960,Q9BSK2,Q06481,P22466,Q9H1E3,Q14118,Q9NR50,P35613,P62993,O00459,Q9UQB8,Q15043,P11166 14 +Regulation of postsynapse organization 0.5937091293116606 1.6513476646766996 0.0986676047309462 1.0 0.4197426458485329 18 P19022,Q14444,P43034,Q15375,Q9UQB8 5 +Regulation of nitric oxide metabolic process 0.671758961071714 1.6489637861560291 0.0991550539734478 1.0 0.4198643795021228 10 P08238,Q08722,P07900,P06280 4 +Regulation of tor signaling 0.6071157143028664 1.6488260870630462 0.0991832689299998 1.0 0.4198643795021228 16 Q8N122,P04062,Q15382,O75844,Q96B36 5 +Ventricular cardiac muscle cell action potential 0.7101389320624379 1.646728664000265 0.0996138297447664 1.0 0.4203041762241033 8 Q14126,Q02487 2 +Regulation of carbohydrate catabolic process 0.6065675940104887 1.6459740368898972 0.0997691044805864 1.0 0.4203041762241033 16 P05067 1 +Protein polyubiquitination 0.4845376280543982 1.6447906593086354 0.1000129890889702 1.0 0.4203041762241033 53 Q16763,Q9Y4X5,Q9C0C9,Q9UIQ6,P61088,Q9BW61,Q13309,Q6UWE0,Q05086,P49459,P46934,Q13356,Q96PU5,P55786,Q5VTR2,Q96J02,Q96FW1 17 +Central nervous system development 0.5059616283697759 1.6443998316098145 0.1000936398864273 1.0 0.4203041762241033 201 O14773,Q06481,Q9BXW9,P01130,O75503,Q5KU26,P05067,P50897,Q9Y6N7,P05556,Q07954,P54802,Q92688,O94992,P19022,Q92542,O94813,Q9Y4G8,P11047,P11166,P04062,P07942,Q96QD8,Q8NB90,O95456,Q15375,Q9UQB8,O14786 28 +Antigen receptor mediated signaling pathway 0.5547760368789074 1.6424264747136863 0.1005016520175363 1.0 0.4206590939739989 26 P28482,P49770,Q13144,P61088,P15311,P17931,Q9NR50,Q92692,Q9Y6K9,P51452,Q07812,P49768,P04439,P23396 14 +Response to thyroglobulin triiodothyronine 0.9340463458110536 1.6414121736870924 0.1007118845460901 1.0 0.421109399103972 2 P16278 1 +Substrate dependent cell migration 0.6883971272731398 1.6411605540938674 0.1007640915460097 1.0 0.421109399103972 9 O94813,O14786,Q9Y6N7 3 +Synaptic vesicle exocytosis 0.5915798479804388 1.6398021465077257 0.1010463117544486 1.0 0.4220207229973101 18 P49768,Q7L0J3,Q06787,Q4J6C6 4 +Apoptotic dna fragmentation 0.7439534086284851 1.639263855295085 0.1011583201846781 1.0 0.4222204506185362 6 O00115 1 +Response to corticosteroid 0.5541921419287082 1.6388263560995235 0.1012494285019742 1.0 0.4223327461547158 26 O94813,P04062,P16278 3 +Regulation of cardiac muscle cell action potential 0.7079681303845087 1.6376173772389364 0.1015015357723685 1.0 0.4229739583032939 8 Q14126,Q02487 2 +Leukocyte differentiation 0.462977272354076 1.6365378754305075 0.1017270655218089 1.0 0.4235193905078858 70 O15347,P05556,Q6YHK3,P01889,P78536,P04062,Q9BXW9,P09429,Q14739,Q15904,P05067,Q9Y4B6,P29317,P02786 14 +T cell activation 0.4774954160640532 1.635173285152575 0.1020127267344521 1.0 0.424440048361307 59 P78536,P04062,Q9BXW9,Q92542,P30825,P09429,Q08722,P02786,P04439,P62942,P78310,P10644,P23396 13 +Glomerulus development 0.7716161330926552 1.634465421280881 0.1021611611666979 1.0 0.4247742020208266 5 P11047,O95747,Q04721 3 +Triglyceride biosynthetic process 0.7422991999815073 1.632660480348347 0.1025404234714182 1.0 0.424927150769342 6 P01130 1 +Cellular response to low density lipoprotein particle stimulus 0.9530460624071324 1.6318930737088244 0.1027020133932965 1.0 0.424927150769342 3 P01130,O15118 2 +Neuroinflammatory response 0.9530460624071324 1.6318930737088244 0.1027020133932965 1.0 0.424927150769342 3 P01130,P53634 2 +Neuron migration 0.5400341518050324 1.6302587361213805 0.1030468247186129 1.0 0.424927150769342 29 O94898,Q9Y4G8,Q92859,P43034,P46108,A0MZ66,Q13885,Q15154,P49768,O14786 10 +Camera type eye development 0.501769924475922 1.630231705251806 0.10305253540051 1.0 0.424927150769342 41 Q99471,P54802,Q9P273,Q14517,P11047,P48681,Q04721,P29317,Q07812,P49768,Q15648,O14786 12 +Synaptic transmission glutamatergic 0.7265838117344192 1.6301810620689237 0.1030632352197713 1.0 0.424927150769342 7 P49768,P19022,P51790 3 +Negative regulation of lymphocyte mediated immunity 0.8228261339787486 1.6300128858779614 0.1030987735828321 1.0 0.424927150769342 4 P04439 1 +Establishment or maintenance of monopolar cell polarity 0.6484117477809592 1.627284187445626 0.1036767546670214 1.0 0.4265076248903482 11 Q14517 1 +Positive regulation of endothelial cell proliferation 0.6375029877138019 1.6258525154100052 0.1039810335876598 1.0 0.4272250087068248 12 Q8N122,P26583,P09429,O14786 4 +Negative regulation of leukocyte proliferation 0.6662422379651151 1.624277632712784 0.1043165687108387 1.0 0.4283360730211592 10 Q96J02,P10644,P22466 3 +Negative regulation of phagocytosis 0.7248941270734341 1.623298691669448 0.1045255691042426 1.0 0.4289265087758626 7 P09429,Q08722 2 +Morphogenesis of a polarized epithelium 0.6257420206213362 1.6221942284819515 0.1047617670924185 1.0 0.4293606144850009 13 Q13308,Q14517 2 +Fc gamma receptor signaling pathway 0.7684794263046495 1.622193601846021 0.104761901223537 1.0 0.4293606144850009 5 Q06481 1 +Regulation of actin cytoskeleton reorganization 0.6356299439926218 1.616952285911305 0.1058885807606504 1.0 0.4330565360052233 12 Q9Y624,P52565,Q04721,Q9UQB8,O14786,Q9H6U6 6 +Regulation of cellular component movement 0.483529236457642 1.6166935390362285 0.1059444492628374 1.0 0.4330565360052233 162 Q14126,Q06481,O94898,P78318,O00560,Q13526,P67870,P84095,Q14118,P05067,Q9Y6N7,Q99538,P16949,Q9Y2I1,P05556,Q13685,P42785,Q07954,Q02487,P11279,O94813,Q9Y4G8,Q8WTV0,Q08722,P43121,P06756,P09429,P07942,P29317,O14786 30 +Cardiac septum morphogenesis 0.7232271421866087 1.6165054637978211 0.1059850730490681 1.0 0.4330565360052233 7 O94813,O14786 2 +Negative regulation of actin filament polymerization 0.5796175273569283 1.6144685105202077 0.1064258417728103 1.0 0.4338752461726637 19 P35080,Q9NYL9,P52907,O94813,P47756,P07737,P58546,Q6IBS0 8 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.9269162210338706 1.6131169560592875 0.1067191007025478 1.0 0.4338752461726637 2 Q06481 1 +Positive regulation of stress activated protein kinase signaling cascade 0.6124936646704694 1.612922734119666 0.1067612953621528 1.0 0.4338752461726637 14 P09429,O00560,P05067,Q969S3,P29372 5 +Chondrocyte differentiation 0.6237076907005753 1.612262819654187 0.1069047603722259 1.0 0.4338752461726637 13 Q15643,Q15043,Q92896 3 +Dna catabolic process endonucleolytic 0.7018137094378823 1.611751492096918 0.1070160276846889 1.0 0.4338752461726637 8 O00115 1 +Positive regulation of adaptive immune response 0.6062903380437044 1.6117154825839226 0.1070238669834275 1.0 0.4338752461726637 15 P02786,P01889,P04439,Q92692 4 +Small rna loading onto risc 0.7368648965626274 1.61094676027687 0.107191326979001 1.0 0.4340824369196533 6 Q5KU26 1 +Protein polymerization 0.4461409377020106 1.6078719665011156 0.1078632226906615 1.0 0.4350820940008824 78 Q9H444,Q9Y3E7,Q15691,Q9NYL9,Q9UJU6,Q13526,P47756,P07737,Q16512,P23258,P62993,P16949,Q16763,P04350,Q96P70,O15143,O95429,Q14247,Q12959,Q02790,Q9NSV4,P63000,O94813,Q08379,P07900,Q6IBS0,P35080,O00429,P36405,Q96CW5,Q14203,Q9UQB8,P23396 33 +Neuron projection extension involved in neuron projection guidance 0.946210995542348 1.60730019959406 0.1079885305475949 1.0 0.4350820940008824 3 O94813,O14786 2 +Positive regulation of dendritic spine development 0.6335887276740384 1.6072454317895324 0.1080005394495962 1.0 0.4350820940008824 12 Q14444,P43034,Q06787,P49768,Q9UQB8 5 +Cell junction assembly 0.4422297788838453 1.6070952242546508 0.1080334807868617 1.0 0.4350820940008824 80 P19022,Q9Y624,Q13641,Q9Y4G8,P11047,Q15375,P05067,P29317,O14786 9 +Regulation of amino acid transport 0.7207883412405783 1.6065611005890483 0.1081506814681372 1.0 0.4350820940008824 7 P05556,Q7L0J3 2 +Response to tumor cell 0.7356658576854793 1.6061515933523696 0.1082406061882204 1.0 0.4350820940008824 6 P04439,P09429,Q92692 3 +Positive regulation of activated t cell proliferation 0.9245395127748068 1.6036832738993292 0.1087838845784097 1.0 0.4368622666402802 2 P09429 1 +Regulation of adaptive immune response 0.5739581736662757 1.60220018221534 0.1091113498023408 1.0 0.4375829225195189 20 P01889,P09429,Q92692,P02786,P04439 5 +Antigen processing and presentation of endogenous antigen 0.6994020482789244 1.6016020849764472 0.1092436294728651 1.0 0.4375829225195189 8 P04439,P01889 2 +Antigen processing and presentation of endogenous peptide antigen 0.6994020482789244 1.6016020849764472 0.1092436294728651 1.0 0.4375829225195189 8 P04439,P01889 2 +Negative regulation of neuron projection development 0.5529289931945788 1.6009349702342308 0.1093913231361545 1.0 0.4375829225195189 25 Q9NQX7,O94898,Q8N0X7,Q15375,P49768,O14786 6 +Negative regulation of multicellular organismal process 0.4500263373648263 1.5997095981312957 0.1096630216027692 1.0 0.4375829225195189 115 O15347,Q9UIQ6,Q06481,P01130,Q6GQQ9,P67870,Q9Y6N7,Q99538,P78536,P49768,P53634,O94813,Q9Y4G8,P04062,P09429,Q53EL6,Q15375,Q16850,P29317,O43847,O14786 21 +Regulation of neural precursor cell proliferation 0.6039179438727482 1.5995671232396758 0.1096946467622912 1.0 0.4375829225195189 15 P55209,Q06481 2 +Polysaccharide metabolic process 0.5768966067222596 1.5993414863072457 0.1097447461520693 1.0 0.4375829225195189 19 P10253,O43505 2 +Regulation of appetite 0.9233511586452772 1.5989661470399572 0.1098281248220927 1.0 0.4375829225195189 2 P80303 1 +Negative regulation of response to food 0.9233511586452772 1.5989661470399572 0.1098281248220927 1.0 0.4375829225195189 2 P80303 1 +Regulation of response to food 0.9233511586452772 1.5989661470399572 0.1098281248220927 1.0 0.4375829225195189 2 P80303 1 +Heart valve development 0.6785230702029206 1.5983045367217104 0.10997521824826 1.0 0.4379037443323575 9 O94813 1 +Negative regulation of small gtpase mediated signal transduction 0.6781247886567585 1.5965728778500947 0.1103609486725671 1.0 0.4384981046983457 9 P05556,O94813 2 +Dendritic cell differentiation 0.7332651837181551 1.5965464207333464 0.1103668503255417 1.0 0.4384981046983457 6 P49768,P01889,Q04721,P09429 4 +Positive regulation of cilium assembly 0.7178971056469787 1.5947630256815089 0.1107652381696746 1.0 0.4391885091501626 7 Q16181,Q9P2S5,Q9UHD8,Q15555 4 +Cell projection assembly 0.4478263738791486 1.593059693675221 0.1111468003161466 1.0 0.4401707721129516 113 Q15691,Q96J42,P15311,O00560,Q9UJU6,Q9H6U6,P84095,P47756,A0MZ66,P07737,Q9BXI6,Q8TC07,Q4KMP7,Q9H4M9,Q9H223,P05556,Q9Y5K6,P50395,P51114,O95429,Q14247,P63000,O94813,Q9Y4G8,Q06787,Q9Y6W5,Q6IBS0,Q9P289,Q9Y366,P11233,P35080,Q9P2S5,Q9BZH6,Q8IVD9,Q16181,Q9ULC3,Q96PY6,P36405,Q15154,P29317,A6NIH7,Q14203,O14786 43 +Keratinocyte differentiation 0.5753862577983104 1.5909356087785511 0.1116240677667306 1.0 0.4417948963715728 19 Q6YHK3,Q13510 2 +Regulation of actin filament based process 0.4328288218275638 1.5900364651093857 0.1118265857347766 1.0 0.4419281770562446 95 Q14126,Q9UJU6,Q9H6U6,P84095,P47756,P62993,P16949,Q07954,Q04721,O15143,P60983,O95429,Q02487,Q14247,Q12959,O94813,Q86VI3,P52565,Q13177,Q9Y624,P46108,Q08722,Q9UQB8,O14786 24 +Embryonic heart tube development 0.696491252031635 1.5893420900893014 0.1119831810500229 1.0 0.4421520798001505 8 P49768,P42892,Q04721 3 +Positive regulation of carbohydrate metabolic process 0.7310782058831057 1.5877911577235528 0.1123335716023337 1.0 0.4423943996346009 6 P05067 1 +Vesicle mediated transport 0.5138497955196764 1.5875308007501374 0.1123924767582247 1.0 0.4423943996346009 392 P55899,O60271,Q9Y3E7,Q14746,Q06481,O95219,P01130,Q9UJU6,O75503,O15127,O00560,P84095,P20645,Q5KU26,P05067,P11717,P50897,Q9BXI6,P02786,O95772,Q9NPF0,Q9UBG0,O43760,Q9H4M9,Q4J6C6,Q14108,Q99523,P05556,Q8TEY7,Q15643,Q07954,Q9UEU0,Q08380,P60520,Q0IIM8,Q8NBN3,P49768,Q96ED9,O15260,P19022,O15400,O15118,P11279,Q08431,Q06787,Q15904,P51790,Q7L0J3,Q96PU5,Q8TD16,Q8WTV0,O43731,P42566,P11233,P06756,Q9Y678,Q9BZH6,Q9UMY4,Q5VW38,P09429,Q9C0C9,Q7Z7H5,O60664,Q8N3F8,P35606,Q9UNF0,Q9H9C1,Q92734,Q96L92,Q08722,Q14203,P09496,O14786 73 +Central nervous system neuron axonogenesis 0.7596057001051851 1.5874309307270054 0.1124150785790454 1.0 0.4423943996346009 5 P08238,O94813,P43034 3 +Regulation of bicellular tight junction assembly 0.6758447367026228 1.5866552215964498 0.112590753182673 1.0 0.4426909590171091 9 Q9Y624 1 +Response to cholesterol 0.9197860962566852 1.5848138387056467 0.1130086372322454 1.0 0.4438034720678868 2 Q15126 1 +Response to sterol 0.9197860962566852 1.5848138387056467 0.1130086372322454 1.0 0.4438034720678868 2 Q15126 1 +Dna catabolic process 0.675131085641359 1.5835494936568375 0.113296275159245 1.0 0.4444024436478912 9 O00115 1 +Penetration of zona pellucida 0.9191919191919212 1.5824550092678695 0.1135457353414635 1.0 0.4451155226913867 2 P07686 1 +Positive regulation of ion transmembrane transport 0.5396664699509266 1.5802241196685471 0.1140555500065256 1.0 0.446316126081455 27 P08183,P22466 2 +Embryonic morphogenesis 0.4291852082835395 1.5792590559881916 0.1142766491142872 1.0 0.44664990961009 85 Q9BVC5,P42892,Q14118,P07737,P62993,P25440,P05556,P54802,Q04721,Q07812,P49768,Q13308,Q9NX62,Q12959,P67809,O95747,Q14651,Q15648,P11233,P10644,P06756,P07942,P63173,P11274,P29317,Q92541 26 +Regulation of cyclic nucleotide phosphodiesterase activity 0.937899635974187 1.5773759521554531 0.1147090453867547 1.0 0.4478343661248092 3 O00170 1 +Negative regulation of microtubule polymerization 0.7283874004227652 1.5770123562651333 0.114792681969331 1.0 0.4478343661248092 6 Q15691,P16949,P04350 3 +Vitamin d metabolic process 0.9377270930815124 1.576754528453827 0.1148520181898073 1.0 0.4478343661248092 3 Q99538 1 +Sodium ion transport 0.5316345206362714 1.575902180943832 0.1150483482985209 1.0 0.4478968469171513 29 Q9H2J7,P08195,P27105,Q96QD8 4 +Jnk cascade 0.5655745735306226 1.575304315520405 0.115186218345882 1.0 0.4478968469171513 21 P09429,Q53EL6,O00560,P43034,P05067,Q969S3,Q96J02,Q92905 8 +Regulation of leukocyte mediated immunity 0.5186778146570069 1.574323138544141 0.115412763077618 1.0 0.4478968469171513 34 P01889,O95219,P09429,P11279,P02786,P04439 6 +Mammary gland epithelium development 0.6728377144376788 1.5735641388288473 0.1155882493458624 1.0 0.4483133869086574 9 Q9Y6N7,Q15648,P29317,Q86VI3 4 +Cell matrix adhesion 0.4979346827164513 1.5718622519705978 0.1159825005416239 1.0 0.4490075782739368 40 P05556,Q14247,Q13418,Q9H2G2,Q9H6U6,Q9UM22,Q14118,P42771,P11274,O14786,P06756,Q99828 12 +Nucleotide salvage 0.7269561986098153 1.571276377815375 0.1161184656948948 1.0 0.4490075782739368 6 Q9BZX2,P07741 2 +Cell communication involved in cardiac conduction 0.6259309891076197 1.5707612267612527 0.1162381214355159 1.0 0.4490075782739368 12 Q14126,Q02487 2 +Regulation of lamellipodium assembly 0.5921423980046521 1.5706516677888112 0.1162635815284094 1.0 0.4490075782739368 16 O94813 1 +Renal filtration 0.8069995064829313 1.570076870610582 0.1163972287887489 1.0 0.4490075782739368 4 P43121 1 +Positive regulation of t cell mediated immunity 0.711643487596541 1.5692122394538124 0.1165984932329227 1.0 0.4490075782739368 7 P04439,P01889,Q92692 3 +Positive regulation of cholesterol storage 0.9153297682709468 1.5671220966213868 0.1170861551939468 1.0 0.4501349107854401 2 Q8WTV0 1 +Negative regulation of plasma membrane bounded cell projection assembly 0.7258488741042225 1.5668370832291174 0.1171527770241218 1.0 0.4501349107854401 6 P47756,O94813,P50395 3 +Ensheathment of neurons 0.5424185449291583 1.5659666540390256 0.1173564239417128 1.0 0.4506541486798524 26 O75312,P53634,Q12959,Q92542,Q13418,Q14118,Q96P11,P07686,O15121,Q13144,P18074 11 +Vesicle mediated transport in synapse 0.5079289549605235 1.5654494264716583 0.1174775668339616 1.0 0.4507242626633628 37 P19022,P51790,P49768,Q7L0J3,Q4J6C6 5 +Activation of cysteine type endopeptidase activity 0.7253155855031977 1.5646986971419754 0.1176535741293971 1.0 0.4507242626633628 6 Q99538 1 +Regulation of membrane potential 0.4607467009285548 1.5644293722288167 0.1177167673387704 1.0 0.4507242626633628 66 Q14126,Q02487,P04062,Q8N0X7,Q06787,Q9UQB8,P05067,O75844,P49768,P78310,Q96PU5,Q9BSK2 12 +Cell surface receptor signaling pathway involved in cell cell signaling 0.4415832730409587 1.5640791987769775 0.1177989703166211 1.0 0.4507242626633628 78 P19022,Q07954,Q13641,Q13526,P67870,Q9UQB8,Q13308,Q14168,P05067,Q13283,P49768,Q9H2V7 12 +Cardiac chamber morphogenesis 0.6244326878491355 1.5636104184802753 0.1179090866712404 1.0 0.4507242626633628 12 O94813,Q04721,Q9Y6N7,Q15648,P62942,O14786 6 +Rna interference 0.6526721161526559 1.563347323207584 0.1179709230461383 1.0 0.4507242626633628 10 O94992,Q5KU26 2 +Type b pancreatic cell development 0.8048652178903868 1.5619829662139797 0.1182920016970778 1.0 0.451219551280955 4 P19022 1 +Positive regulation of supramolecular fiber organization 0.4799029353927491 1.5613574818477371 0.1184394279487492 1.0 0.4512913221776317 44 P35080,O95429,Q15691,Q14247,Q12959,P63000,P07737,Q16512,P62993,Q9Y6W5,P05067,P36405,Q08722,P49768,Q14203,Q9UQB8,O14786,P23396 18 +Nerve growth factor signaling pathway 0.933336031289664 1.5609374575446424 0.118538508237701 1.0 0.4512913221776317 3 Q99523 1 +Myeloid cell development 0.5837922466063671 1.5605919849795022 0.1186200510862154 1.0 0.4512913221776317 17 P05067 1 +Regulation of spontaneous synaptic transmission 0.9326091963745546 1.5583189028156867 0.1191576701695296 1.0 0.4523761503978974 3 P05067 1 +Spontaneous synaptic transmission 0.9326091963745546 1.5583189028156867 0.1191576701695296 1.0 0.4523761503978974 3 P05067 1 +Presynapse organization 0.7088277372337589 1.5576938736920205 0.1193058334577237 1.0 0.452591564293487 7 P05067 1 +Stem cell proliferation 0.6331804915089936 1.5565932160193048 0.1195670954939869 1.0 0.4533212415904588 11 P08183,P26583,P48681,P04062 4 +Negative regulation of autophagy 0.5543141473225799 1.5557309117186169 0.119772092778402 1.0 0.4535756052368041 23 P10619 1 +Positive regulation of monocyte chemotaxis 0.9303238970688228 1.5500849929080265 0.1211211175198929 1.0 0.4573678019781032 3 Q99538 1 +Regulation of gliogenesis 0.5997523905668741 1.548789940416812 0.1214322245560772 1.0 0.458016727712085 14 P01130 1 +Regulation of protein tyrosine kinase activity 0.5937171035135786 1.5471881001560008 0.1218178946031072 1.0 0.4592080863605955 15 P49768,P78536,P05067 3 +Glycolipid transport 0.8005435822324702 1.5455866248678156 0.1222044334595389 1.0 0.4592524667004651 4 P61916 1 +Regulation of autophagy 0.4335221760142185 1.5451725132707173 0.1223045410134113 1.0 0.4592524667004651 101 Q8N122,P04062,O95219,O15118,P09429,Q93050,P10619,Q9Y6K9,O00459,O75844,P07602,Q13137 12 +Positive regulation of protein localization to cell periphery 0.5563799292363144 1.544184733525076 0.1225435861576913 1.0 0.4592524667004651 22 P05556,Q12959,Q07954,P63096,P17931,P84095,P29317,Q14651,Q99828 9 +Regulation of heart rate by cardiac conduction 0.7199117983114888 1.5430155693260494 0.1228269983718768 1.0 0.4593767558025496 6 Q02487 1 +Bundle of his cell to purkinje myocyte communication 0.7479678013660205 1.5417450766100718 0.1231355534242828 1.0 0.4594368463706154 5 Q02487 1 +Amine transport 0.6654855915741691 1.5415040560908453 0.1231941565227929 1.0 0.4594368463706154 9 P05556,Q7L0J3 2 +Maintenance of location 0.446202962859825 1.541456902122122 0.1232056243535673 1.0 0.4594368463706154 74 P04062,Q13438,O60664,P02792,P10253,P07686,P49768,P17900,P62942,Q8WTV0,O43731,Q9H4M9,P06756 13 +Activation of immune response 0.4725619674200508 1.5401633498205154 0.1235205410839832 1.0 0.4601494788846272 52 O94992,Q13177,Q13144,P61088,Q06481,P09429,P17931,Q9NR50,Q92692,Q9Y6K9,Q07812,P49768,P04439,Q08722,P23396 15 +Notch signaling pathway 0.5629801006894893 1.540097314937366 0.1235366341912818 1.0 0.4601494788846272 20 Q92542,P05067,P78536,Q9Y6N7 4 +Regulation of dendrite morphogenesis 0.5792025419256196 1.5360067175408991 0.1245367328153743 1.0 0.4630879753869601 17 Q14444,P43034,Q9Y4G8,Q96PU5,Q9UQB8 5 +Regulation of t cell activation 0.5069338532304758 1.5350843348878034 0.1247631136808848 1.0 0.4634058508147153 36 P09429,P30825,Q08722,P02786,P04439,P10644,P23396 7 +Regulation of proteolysis 0.4844849679701315 1.534612876600138 0.1248789478010943 1.0 0.4635743333158005 178 Q96KB5,Q06481,O94898,P78318,O00560,Q12834,Q9GZP4,P61201,P05067,Q9Y6N7,Q9BXI6,Q99538,Q07954,P60520,Q96K76,Q92530,Q92688,P49768,P08238,P53634,Q04323,Q6YHK3,Q9UKS6,Q92542,Q9BW61,Q06787,Q92896,Q15392,Q13177,P78559,Q96J02,O95831,Q9Y4X5,Q9C0C9,Q9NR28,P04062,Q9UMY4,P09429,P04080,P62913,Q15375,O43847,P23396 43 +Defense response 0.5037335589268156 1.5339142088627844 0.1250507599383872 1.0 0.4637017552432738 222 O15347,Q9BQE5,Q9Y3E7,Q06481,O95219,P01130,Q9BXW9,O00584,P26583,Q5KU26,Q9Y6K9,P05067,P02786,P05556,Q12899,P78536,P42785,P22466,O75179,Q08380,Q8IV08,Q9NUQ8,P48960,P53634,O94992,P33527,P11279,P28070,Q13309,P38571,P04439,Q08722,P01889,P04062,P09429,Q53EL6,O43657,Q9Y624,Q9ULC3,Q92692,O60684,O75844,P29317,P10321,Q13137 45 +Transforming growth factor beta production 0.7972651605231807 1.5331420822032953 0.125240850956019 1.0 0.4637017552432738 4 P08238,O75787,P06756 3 +Membrane protein proteolysis 0.5785908878014018 1.5327265065825344 0.1253432553353675 1.0 0.4637017552432738 17 Q9UKS6,P78536,Q92542,O94898,Q14118,P49768,Q8TCT8,O43847 8 +Positive regulation of cysteine type endopeptidase activity 0.5179380753480247 1.532003370038877 0.1255216031370807 1.0 0.4637017552432738 32 P09429,Q92688,Q9Y6N7,Q99538,O95831,P23396 6 +Peptidyl tyrosine modification 0.4761469366807122 1.5317495317877927 0.1255842543585554 1.0 0.4637017552432738 44 P78536,Q96KB5,Q96PY6,Q15375,P05067,P29317,Q13177,P49768,Q9H223,O14786 10 +Suppression of viral release by host 0.7453899125346735 1.5316120334617662 0.1256182012531945 1.0 0.4637017552432738 5 Q9Y3E7 1 +Cellular carbohydrate metabolic process 0.4652258331761593 1.5309573800760012 0.1257799263819889 1.0 0.4640383374877866 59 Q14108,Q92520,Q7LGA3,O43505,P10253,P16278,O75844,Q9NX62 8 +Bone cell development 0.6823387742493732 1.5295843144451478 0.1261196544594507 1.0 0.4642353588037368 8 Q15904,P43034,Q04721 3 +Stress fiber assembly 0.5316414155651908 1.529491249787686 0.1261427066368114 1.0 0.4642353588037368 27 P05556,P35080,O95429,P63000,Q08722,Q9Y624,P07737,Q9Y6W5,Q13177,P16949,O14786 11 +Triglyceride metabolic process 0.6273151014214758 1.529268993395707 0.126197772969435 1.0 0.4642353588037368 11 P01130 1 +Extrinsic apoptotic signaling pathway 0.473838111076163 1.52903094126124 0.1262567736241844 1.0 0.4642353588037368 48 Q99523,Q9NQX7,P06756 3 +Appendage development 0.549473409732226 1.527019899374063 0.1267560632043041 1.0 0.4655507447001186 23 P42892,O95747,Q04721,P49768,Q15648,Q9NX62 6 +Protein k48 linked ubiquitination 0.6266738308118378 1.5262783316471518 0.1269405626413098 1.0 0.4659682037134687 11 P49459,Q13309,Q96PU5 3 +Regulation of lamellipodium organization 0.5702939813488987 1.5237159062419936 0.1275796942646405 1.0 0.4674278630123511 18 O94813 1 +Mannose metabolic process 0.7428507373714773 1.521626809801326 0.1281026159864107 1.0 0.4681667952544121 5 O00754 1 +Amino acid import 0.6256721972288815 1.5216057980545818 0.1281078838885607 1.0 0.4681667952544121 11 P05556,P30825,P08195 3 +Dna methylation involved in gamete generation 0.9037433155080228 1.5211234363645003 0.1282288641904276 1.0 0.4681667952544121 2 Q8NB78 1 +Regulation of ion transmembrane transport 0.4569167433150025 1.5188633903826143 0.1287968857505226 1.0 0.4698979004253676 65 P05556,P22466,P08183,Q06787,P27105,P05067,O75844,P49768,P62942,Q96PU5 10 +Regulation of b cell activation 0.5758689760020379 1.5181185711214895 0.1289845102898479 1.0 0.4701121267601403 17 P02786 1 +Heart process 0.5105088086388476 1.5180629151686575 0.1289985388875119 1.0 0.4701121267601403 34 Q14126,Q02487,P10253,O75844,P78310 5 +Positive regulation of regulated secretory pathway 0.6990040213924071 1.5174440945109928 0.1291545982274275 1.0 0.4704202365116383 7 P11279 1 +Tissue morphogenesis 0.4330265188944455 1.5171371867417418 0.1292320511642397 1.0 0.4704418553173043 80 P67870,Q14118,P62993,Q9Y6N7,P62942,P05556,P78536,Q9UIW2,Q14517,Q04721,P49768,Q13308,O94813,O95747,P11233,P10644,P43034,Q15375,P29317,O14786 20 +Negative regulation of catalytic activity 0.4749735676446964 1.5159150062896647 0.1295408452994688 1.0 0.4710445994361006 164 Q06481,P78318,Q12834,P06280,O00170,P61201,P05067,P48681,P62942,Q99523,P04792,Q07954,P60866,Q96K76,Q92530,P49768,Q96B36,Q15043,P60983,Q6YHK3,O94992,O95429,O94813,Q9BTT0,Q15392,P10644,Q8N122,O43924,Q9C0C9,P04062,Q53EL6,P04080,P62913,Q9Y624,Q01105 35 +Collateral sprouting in absence of injury 0.901960784313729 1.5140475439179042 0.1300137814879942 1.0 0.4718109020409381 2 P05067 1 +Negative regulation of collateral sprouting 0.9019607843137278 1.5140475439178989 0.1300137814879955 1.0 0.4718109020409381 2 Q15375 1 +Membrane protein intracellular domain proteolysis 0.9203225128314606 1.5140397910245182 0.1300157477035306 1.0 0.4718109020409381 3 Q8TCT8 1 +Commissural neuron axon guidance 0.920059435364042 1.5130914765163477 0.1302564243793817 1.0 0.4718109020409381 3 P13591,O14786 2 +Positive regulation of protein polyubiquitination 0.7919013886625934 1.5127712337869594 0.1303377781552557 1.0 0.4718109020409381 4 Q13309 1 +Regulation of membrane repolarization 0.7404130662766542 1.5120368341506327 0.1305244923429156 1.0 0.4718109020409381 5 O75844 1 +Immune response to tumor cell 0.7914251517983396 1.5109619620204076 0.1307981424965043 1.0 0.4718109020409381 4 P04439,P09429 2 +Positive regulation of small gtpase mediated signal transduction 0.6233570366067926 1.5107999339335 0.1308394315627645 1.0 0.4718109020409381 11 Q9Y624,P06756 2 +Regulation of neuronal action potential 0.90106951871658 1.5105097499238391 0.1309134034311494 1.0 0.4718109020409381 2 P04062 1 +Regulation of transmission of nerve impulse 0.90106951871658 1.5105097499238391 0.1309134034311494 1.0 0.4718109020409381 2 P04062 1 +Regulation of erbb signaling pathway 0.5864233409701177 1.5095986999273865 0.1311458533007425 1.0 0.4718109020409381 15 Q99538,P78536 2 +Positive regulation of leukocyte degranulation 0.7115897718280987 1.5095720091979217 0.1311526681297219 1.0 0.4718109020409381 6 P11279 1 +Lipid catabolic process 0.4411467487579743 1.5095253731703566 0.1311645761647901 1.0 0.4718109020409381 75 Q8NHP8,P04066,Q13510,P01130,Q8NCC3,P06280,P07686,P50897,P38571,P17900,Q8WTV0,P06865 12 +Positive regulation of interleukin 1 production 0.6404503686432113 1.5082351720224876 0.1314943484301218 1.0 0.4719917162006976 10 P05067,P09429 2 +Walking behavior 0.7903292464317444 1.5067981605763454 0.1318624012126323 1.0 0.4726925750281721 4 O15118 1 +Response to dsrna 0.5848803401918762 1.5016325011794285 0.1331920448057431 1.0 0.4763387068564879 15 Q5KU26 1 +Organic cation transport 0.6754724881317029 1.5005083796238068 0.1334827645282059 1.0 0.4763387068564879 8 O43772,Q96QD8 2 +Glial cell migration 0.6111629940907098 1.500111020274728 0.1335856467740903 1.0 0.4763387068564879 12 P07686 1 +Positive regulation of triglyceride metabolic process 0.9163781256800548 1.4998208175439212 0.1336608233373266 1.0 0.4763387068564879 3 P01130 1 +Mammary gland epithelial cell proliferation 0.6749830590324756 1.498433892033319 0.1340205563223069 1.0 0.4770425553954883 8 Q9Y6N7,Q15648,P29317,Q86VI3 4 +Action potential 0.5446201513768045 1.4981620024285085 0.1340911652365852 1.0 0.4770425553954883 23 Q14126,Q02487,P04062,Q96PU5,P78310 5 +Activation of gtpase activity 0.5443334671008081 1.4964551166558169 0.1345350957906528 1.0 0.4778465767337549 23 Q0IIM8,Q86X10,P84095,P46108,P46060,P29317,P11274,Q9BXI6,Q8TC07,Q9H6U6 10 +Cobalamin metabolic process 0.7875263936117598 1.496146835491731 0.1346153952255657 1.0 0.4778737559599414 4 Q9NPF0 1 +Amide transport 0.4757016263587788 1.4945507310421808 0.1350317326330503 1.0 0.4785769058514036 43 P08183,P07602,O00400,P22466 4 +Base excision repair ap site formation 0.8969102792632211 1.494001691815798 0.1351751770833575 1.0 0.4786484613120707 2 P13051 1 +Regulation of ventricular cardiac muscle cell action potential 0.707384253830976 1.4926494990233137 0.1355289590884145 1.0 0.4786484613120707 6 Q02487 1 +Regulation of small gtpase mediated signal transduction 0.4753970157079265 1.4921733985778012 0.1356536940956147 1.0 0.4786484613120707 43 P05556,Q07960,O94813,Q86X10,O75955,Q9Y624,Q9H0H5,P52565,P46108,Q04721,Q9Y6N7,P16949,O14786,P06756 14 +Cellular response to manganese ion 0.8960190136660762 1.4904646615059485 0.1361021015850991 1.0 0.4787158405548867 2 P05067 1 +Negative regulation of guanyl nucleotide exchange factor activity 0.8960190136660731 1.490464661505935 0.1361021015851027 1.0 0.4787158405548867 2 P16949 1 +Response to thyroid hormone 0.6921696988886258 1.4893873632804435 0.1363853942423516 1.0 0.4787158405548867 7 Q9Y376,P04062 2 +Outer mitochondrial membrane organization 0.7345864821652082 1.4890999875169884 0.1364610411020859 1.0 0.4787158405548867 5 Q9NS69,O14737,P07900 3 +Negative regulation of response to biotic stimulus 0.5538073770682311 1.4879486380130726 0.1367644393872054 1.0 0.4787158405548867 20 P01889,O43657,Q9Y3Z3,Q7Z739,P04439,Q96J02 6 +Nik nf kappab signaling 0.5464627895022123 1.4861242941033233 0.1372462474330096 1.0 0.4787158405548867 22 O43657,P05067,Q53EL6 3 +Cochlea development 0.73377038502574 1.485885789885972 0.1373093328826438 1.0 0.4787158405548867 5 Q13308 1 +Regulated exocytosis 0.4899916050931518 1.485629184738229 0.1373772310815444 1.0 0.4787158405548867 39 O95219,P11279,P49768,Q7L0J3,O43760,Q4J6C6 6 +Post golgi vesicle mediated transport 0.4678792118371829 1.485550795095559 0.1373979782888186 1.0 0.4787158405548867 49 P11279,Q99523,O15127,Q4J6C6 4 +Interleukin 12 production 0.6912047194580081 1.4854224449463989 0.1374319536458457 1.0 0.4787158405548867 7 P01889,P09429 2 +Regulation of phospholipid catabolic process 0.9123328380386332 1.485237041668391 0.1374810428806143 1.0 0.4787158405548867 3 P01130,Q8WTV0 2 +Cell cell signaling by wnt 0.4490063550010896 1.4835355569664337 0.1379321766730088 1.0 0.4787158405548867 68 P19022,Q07954,Q13526,Q13641,P67870,P05067,P49768,Q9H2V7 8 +Positive regulation of cyclin dependent protein kinase activity 0.7841659141873928 1.4833726744999467 0.1379754233097938 1.0 0.4787158405548867 4 P08238,P78536 2 +L alpha amino acid transmembrane transport 0.5974255661960767 1.4832392453722545 0.1380108576290499 1.0 0.4787158405548867 13 P05556,P49768,P30825,P08195 4 +Negative regulation of protein maturation 0.733006177642666 1.4828756282848474 0.1381074577825036 1.0 0.4787158405548867 5 Q92896 1 +Endosome transport via multivesicular body sorting pathway 0.6069912468502128 1.4800883354631162 0.1388496740688858 1.0 0.4787158405548867 12 Q99523 1 +Multivesicular body sorting pathway 0.6069912468502128 1.4800883354631162 0.1388496740688858 1.0 0.4787158405548867 12 Q99523 1 +Neurotransmitter uptake 0.7039081071739177 1.478651536469554 0.1392334711748031 1.0 0.4787158405548867 6 P05556,O75955 2 +Regulation of peptidyl tyrosine phosphorylation 0.5099348255751698 1.4779634005938578 0.1394175747480208 1.0 0.4787158405548867 32 P78536,Q15375,P05067,P49768,Q9H223,O14786 6 +Regulation of toll like receptor signaling pathway 0.6508228678253026 1.4773555977234454 0.1395803418685701 1.0 0.4787158405548867 9 Q06481 1 +Regulation of immune system process 0.4925139246561805 1.4758667079109176 0.1399796784153599 1.0 0.4787158405548867 207 O15347,Q06481,O95219,P01130,P30825,Q9BXW9,P26583,P84095,Q5KU26,Q9GZP4,Q9Y6K9,P05067,P02786,Q99538,P62942,Q9NPF0,P78536,P22466,O75179,Q9NR50,P49768,P53634,Q8TCT8,O94992,P11279,P28070,O94813,O00115,P04439,P10644,P01889,P09429,O43657,Q92692,Q08722,P23396 36 +Immune response 0.4981754177995768 1.474445549656715 0.1403616680349053 1.0 0.4787158405548867 222 P55899,O15347,Q96SB4,Q06481,P19525,O95219,Q6GQQ9,P00492,O00584,P17931,P26583,Q9UJU6,Q5KU26,Q9Y6K9,P05067,P02786,P62942,Q9BUI4,Q13283,Q12899,P78536,Q07954,P61088,O75179,O00178,Q9NR50,O95373,O95801,P48960,Q04721,Q07812,Q13740,P49768,P53634,P08238,Q8TCT8,O94992,Q8IWZ3,O15400,P11279,O96028,P54578,P28070,O75955,Q13309,P07900,P36915,Q9Y3Z3,O00115,Q9UQ84,Q13177,P04439,Q15648,Q96J02,Q7Z739,P01889,Q13144,P09429,O43657,Q92692,P07437,P46108,Q08722,P13051,P10321,Q13137,P23396 67 +Positive regulation of actin cytoskeleton reorganization 0.7028323620930156 1.474317837055727 0.1403960348146937 1.0 0.4787158405548867 6 Q9UQB8,O14786 2 +Platelet activating factor metabolic process 0.8918597742127156 1.4739608625529068 0.1404921290762386 1.0 0.4787158405548867 2 Q7L5N7 1 +Neuroepithelial cell differentiation 0.7813038687945921 1.4724902554002344 0.1408885365286618 1.0 0.4787158405548867 4 P19022,P07437 2 +Response to chemokine 0.68790395891952 1.471854127615603 0.1410602732559225 1.0 0.4787158405548867 7 O95747,O94813,Q9Y6N7 3 +Diol metabolic process 0.668672849568366 1.471665300430378 0.1411112822797089 1.0 0.4787158405548867 8 Q13510 1 +Diol biosynthetic process 0.668672849568366 1.471665300430378 0.1411112822797089 1.0 0.4787158405548867 8 Q13510 1 +Ornithine transport 0.8906714200831873 1.4692462890909888 0.1417659992309912 1.0 0.479281399169264 2 P30825 1 +Notch receptor processing 0.907875185735513 1.469166128092526 0.1417877350663849 1.0 0.479281399169264 3 P78536,Q92542 2 +Negative regulation of low density lipoprotein receptor activity 0.907875185735513 1.469166128092526 0.1417877350663849 1.0 0.479281399169264 3 P05067,P06756 2 +Forebrain generation of neurons 0.7294075016927573 1.468696523202038 0.1419151209229339 1.0 0.479281399169264 5 O14786 1 +Microtubule anchoring 0.631251131126965 1.466617483031907 0.1424801413730112 1.0 0.4808796151624771 10 Q8TD16,Q14203,Q9P287,Q14118 4 +Sensory system development 0.4663061640069793 1.464065873677308 0.1431759505139529 1.0 0.4825144272712243 47 Q99471,P54802,Q9P273,Q14517,P11047,P48681,Q04721,P29317,Q07812,P49768,Q15648,O14786 12 +Cell growth 0.4345569058444252 1.4640342910911583 0.1431845792084873 1.0 0.4825144272712243 112 O60271,Q9UJU6,O00560,Q5BJF2,P05067,P50897,P02786,Q9BSK2,P05556,P78536,Q9UIW2,Q96K76,Q13740,O94813,Q8N0X7,Q7Z4V5,P11047,Q96PU5,Q8N122,O43598,P43034,Q15375,O14786 23 +Myeloid cell differentiation 0.421803272251092 1.462979562662861 0.1434729713154336 1.0 0.4832387123978099 83 Q6YHK3,O15347,P04062,Q14739,P26583,Q15904,Q9GZP4,O00115,P05067,P29317,P02786 11 +Axo dendritic protein transport 0.7785356811343822 1.4619623820617484 0.1437515186441464 1.0 0.4834764705894081 4 P78559,Q14168 2 +Protein localization to presynapse 0.7785356811343822 1.4619623820617484 0.1437515186441464 1.0 0.4834764705894081 4 P78559,Q14168 2 +Positive regulation of non motile cilium assembly 0.7273641141230949 1.4606424763100905 0.1441135829902777 1.0 0.4841568686976747 5 Q16181,Q9P2S5,Q9UHD8 3 +Regulation of oxidoreductase activity 0.5710278136586135 1.4595383637569603 0.1444169896022051 1.0 0.4849285133248114 16 P06280 1 +Motor behavior 0.8879976232917439 1.4586399841693285 0.1446642224902277 1.0 0.4852632613670157 2 P04062 1 +Mitotic dna replication checkpoint signaling 0.8874034462269751 1.4562833269053188 0.1453143127076068 1.0 0.4871954887821804 2 Q9Y619 1 +Response to starvation 0.4661530145786063 1.455627625073016 0.1454955870622354 1.0 0.4875547486986167 45 Q8TEY7,Q8N122,Q02487,P54619,P05198,P04062,P60520,Q9H6U6,P13473,Q96QD8,Q6PKG0,P11166 12 +Odontogenesis 0.6012041706346755 1.452268494116277 0.1464269641838123 1.0 0.4901763717054032 12 P07942,P04920,O95747,P35613,Q07812 5 +Pyrimidine nucleotide catabolic process 0.9030581583843376 1.4517999477707526 0.1465572384526199 1.0 0.49036292703018 3 Q9H773 1 +Sodium ion transmembrane transport 0.5405215633995117 1.4512053468854995 0.146722688462725 1.0 0.4906669266435209 22 Q12959,P27105,O95747,Q96PU5,Q9H2J7,Q6P4Q7,P08195 7 +Positive regulation of toll like receptor signaling pathway 0.7746667073735733 1.447244645482207 0.1478284164757592 1.0 0.4930766736350122 4 P09429 1 +Fatty acyl coa metabolic process 0.5796631056115829 1.4470139422996176 0.14789301871114 1.0 0.4930766736350122 14 Q9UMR5 1 +Regulation of endodeoxyribonuclease activity 0.9015258447370916 1.4462759595605084 0.1480998158486506 1.0 0.4932211957040424 3 P09429 1 +Endosome organization 0.4972501456908806 1.4455192872699254 0.1483120794614758 1.0 0.4932238921625825 35 Q14108,Q96ED9,P51790 3 +Oogenesis 0.5897171919993505 1.4451647299316817 0.1484116206953412 1.0 0.4933055285163993 13 P07686 1 +Axo dendritic transport 0.5130524896507161 1.4424887711434675 0.1491645370574994 1.0 0.4946921160184289 28 P43034,Q14203,P05067,P78559,Q14168 5 +Homotypic cell cell adhesion 0.5352664689611313 1.4423459710719253 0.1492047975342905 1.0 0.4946921160184289 23 Q14126,Q02487,Q9Y624 3 +Negative regulation of transmembrane transport 0.5456640539840439 1.441465050147278 0.1494533442446266 1.0 0.4952665483330751 20 Q96PU5,Q06787,P62942,Q06481 4 +Bone development 0.5126706793496613 1.4400080807289817 0.149865112882674 1.0 0.4956066013548713 28 Q15643,Q92896,Q15904,Q32P28,O75844,Q9NX62 6 +Response to bmp 0.5613233115646827 1.439769315743901 0.1499326750830334 1.0 0.4956066013548713 17 Q9C0C9,Q53EL6,Q8N0X7,Q92859,O00400 5 +Cellular homeostasis 0.4646759643806837 1.4391588329328269 0.1501055261589667 1.0 0.4958435636429449 159 O75503,Q9H1E3,Q9BXP2,P05067,P50897,P02786,Q93050,P13473,P10253,Q15043,P02792,Q15904,P51790,P07686,O00459,Q7L0J3,Q96PU5,Q9NUM4,P06756 19 +Rho protein signal transduction 0.526523431547873 1.4389837745866008 0.1501551199113326 1.0 0.4958435636429449 25 P05556,Q07960,O75955,Q9Y624,P84095,A0MZ66,P52565,Q9Y6N7,P16949,O14786 10 +Organic hydroxy compound biosynthetic process 0.4601534300653591 1.437838895871309 0.1504797703746072 1.0 0.4966662968008863 52 Q13510,P04062,Q15126,Q14739,Q9UBM7,Q16850,Q15392 7 +Positive regulation of neurogenesis 0.463625496465556 1.4354223020031198 0.1511667945645307 1.0 0.4981839552332081 45 Q02750,Q14444,Q9UJU6,O94813,Q9UIW2,P43034,Q14118,A0MZ66,Q6IBS0,Q15382,Q9Y6N7,Q9UQB8,P55209,O14786 14 +Negative regulation of epithelial cell migration 0.6068023155829916 1.4333077344108098 0.151769912623829 1.0 0.4985403058412073 11 O94813,P09429 2 +Positive regulation of natural killer cell mediated immunity 0.8978923877036671 1.4331781686234546 0.1518069269389013 1.0 0.4985403058412073 3 P11279 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.8978923877036671 1.4331781686234546 0.1518069269389013 1.0 0.4985403058412073 3 P11279 1 +Negative regulation of t cell proliferation 0.6783796457306523 1.432653006774162 0.1519570254198268 1.0 0.4985403058412073 7 Q96J02,P10644 2 +Hindbrain morphogenesis 0.6234393306676692 1.4311935216029843 0.1523747597485973 1.0 0.4996403112530237 10 P04062,Q02750,Q06124,P58546,P18887 5 +Response to tumor necrosis factor 0.4921328085138445 1.4300031859520508 0.1527161046783269 1.0 0.500282139728105 36 O95429,P78536,Q13510,P04062,P78318,Q8TCT8,P23396 7 +Purine ribonucleoside salvage 0.691291888992795 1.4277766123864208 0.1533561665561087 1.0 0.5010375807884425 6 Q9NRG1,P00491,P00492,P07741 4 +Nucleoside salvage 0.691291888992795 1.4277766123864208 0.1533561665561087 1.0 0.5010375807884425 6 Q9NRG1,P00491,P00492,P07741 4 +Purine nucleoside biosynthetic process 0.691291888992795 1.4277766123864208 0.1533561665561087 1.0 0.5010375807884425 6 Q9NRG1,P00491,P00492,P07741 4 +Actin cytoskeleton reorganization 0.5202593826130949 1.4275164570934185 0.1534310849971987 1.0 0.5010375807884425 26 Q14247,P15311,Q9H6U6,Q9Y624,Q9Y5K6,Q9UQB8,P62993,Q16512,Q13308,P52565,Q04721,P78310,P11233,O14786 14 +Negative regulation of jnk cascade 0.718703538507258 1.4264857988451556 0.1537281632366767 1.0 0.5011267598447992 5 Q96J02,P51452,P43034,Q53EL6 4 +Regulation of actin filament based movement 0.6580369634595822 1.4264594778481368 0.1537357557565832 1.0 0.5011267598447992 8 Q02487 1 +Regulation of neuron projection regeneration 0.7185507098476343 1.425882779999911 0.1539021808113601 1.0 0.5012153757926512 5 O94898 1 +Positive regulation of dna ligation 0.8796791443850283 1.425658367184355 0.1539669794806566 1.0 0.5012153757926512 2 P09429 1 +Negative regulation of natural killer cell mediated immunity 0.8957825512785518 1.4255733669864157 0.1539915285006001 1.0 0.5012153757926512 3 P04439 1 +Fatty acyl coa biosynthetic process 0.6048685341784538 1.4242318433282029 0.154379369830675 1.0 0.5017329519496938 11 Q9UMR5 1 +Negative regulation of sodium ion transport 0.7178358891537437 1.4230621850451213 0.1547181292624804 1.0 0.5022379636519144 5 Q96PU5,O95747 2 +Inositol phosphate catabolic process 0.6892677559020025 1.4196049507823447 0.1557227233060838 1.0 0.5027361995232894 6 Q9NX62 1 +Regulation of protein localization to cell periphery 0.4872963044281022 1.4172098380197906 0.1564215862945164 1.0 0.5027361995232894 37 P05556,O15400,Q12959,Q07954,Q9UEU0,P63096,P15311,P17931,P84095,Q14118,P29317,Q14651,Q99828 13 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.6369374907627354 1.4163776487182682 0.1566649644335664 1.0 0.5027361995232894 9 P48960 1 +Response to ketone 0.4871190656474938 1.4159280202735838 0.1567965800652628 1.0 0.5027361995232894 37 O94813,P04062,P49321,P16278 4 +Positive regulation of fibroblast migration 0.7661200995584863 1.4147220589302731 0.1571500040928726 1.0 0.5027361995232894 4 P05556 1 +Response to extracellular stimulus 0.4088926732439809 1.4137093301050454 0.1574472647681679 1.0 0.5027361995232894 87 Q8TEY7,Q8N122,P80303,Q02487,Q9UMX5,P04062,Q06481,P01130,P13473,Q96QD8,P02786,Q9H773,O95831,P11166 14 +Polyol biosynthetic process 0.583349389292906 1.4136408415504933 0.1574673832053603 1.0 0.5027361995232894 13 Q13510 1 +Interleukin 1 production 0.5930027258686418 1.4127593319858498 0.1577264995814249 1.0 0.5027361995232894 12 P05067,P09429 2 +Collagen catabolic process 0.8922261384816419 1.4127559212673484 0.1577275027760818 1.0 0.5027361995232894 3 Q9UBG0 1 +Amp salvage 0.7655877615911619 1.4126959677159776 0.1577451377038718 1.0 0.5027361995232894 4 P07741 1 +Purine ribonucleotide salvage 0.7655877615911619 1.4126959677159776 0.1577451377038718 1.0 0.5027361995232894 4 P07741 1 +Protein transport along microtubule 0.7139458816532596 1.4077095858263111 0.1592170821958933 1.0 0.5045674409045711 5 P78559,Q14168,P04792,O95817 4 +Ventricular cardiac muscle tissue development 0.6857444057079358 1.405375342349018 0.1599096950166436 1.0 0.505471395396195 6 Q14126,P62942,O75844 3 +Positive regulation of epithelial cell apoptotic process 0.889801395986844 1.4040183302299023 0.1603133912557255 1.0 0.506202709090248 3 Q53EL6 1 +Positive regulation of nf kappab transcription factor activity 0.5119166609724266 1.4038218246556318 0.1603719133086161 1.0 0.506202709090248 27 P23396,P61088,P19525,Q9Y6K9,P05067,P60900,P02786,Q99828 8 +Innate immune response 0.4385801822086998 1.4032453569689285 0.1605436864529268 1.0 0.5065018558692339 125 O15347,Q96SB4,Q06481,P19525,O00584,P17931,P26583,Q5KU26,Q9Y6K9,Q9BUI4,Q13283,Q12899,O75179,O95373,O95801,P08238,O94992,Q8IWZ3,P11279,P54578,Q13309,Q9Y3Z3,Q13177,P04439,Q15648,Q96J02,Q7Z739,P01889,P09429,Q92692,P07437,P46108,Q08722,P10321,Q13137 35 +Carbohydrate transport 0.5603320025149978 1.4028991330725054 0.1606469194411286 1.0 0.506584581056445 16 Q06481 1 +Osteoclast development 0.7627224196570394 1.401789890495011 0.1609779982137511 1.0 0.5073853724245592 4 Q15904,P43034 2 +Response to axon injury 0.5415509810670762 1.401032809614666 0.1612042620816611 1.0 0.5076082410908475 19 O94898,P10586,Q02750,Q14118,P11047,P06493,Q07812 7 +Positive regulation of bmp signaling pathway 0.6704566639909074 1.399992100961472 0.1615156838866607 1.0 0.5076082410908475 7 Q9BRX2,Q9C0C9,Q04721,Q92859 4 +Dichotomous subdivision of terminal units involved in salivary gland branching 0.8731431966726116 1.3997651434285838 0.1615836589886674 1.0 0.5076082410908475 2 O14786 1 +Dichotomous subdivision of an epithelial terminal unit 0.8731431966726116 1.3997651434285838 0.1615836589886674 1.0 0.5076082410908475 2 O14786 1 +Ras protein signal transduction 0.4245945115186355 1.3992381413976802 0.1617415824726493 1.0 0.5076082410908475 78 Q07960,Q9UJU6,O00560,P84095,P62993,A0MZ66,Q9Y6N7,Q13283,P16949,Q9Y2I1,P05556,Q04721,O75955,Q9Y4G8,Q86VI3,Q15392,P11233,Q9Y624,P46108,O14786 20 +Positive regulation of glycolytic process 0.8879855867356706 1.3974758254399675 0.1622705313317571 1.0 0.5082931214763327 3 P05067 1 +Maintenance of blood brain barrier 0.6509873034631961 1.3964420972268574 0.1625814056441954 1.0 0.5086104347367838 8 P05556,Q9Y624 2 +Natural killer cell activation 0.6323070679615859 1.3959992348993573 0.1627147255476866 1.0 0.5086104347367838 9 P11279 1 +Negative regulation of erbb signaling pathway 0.6156484227183264 1.395795239827862 0.1627761642479823 1.0 0.5086104347367838 10 Q99538 1 +Tube development 0.4574685215678403 1.3956020399694915 0.1628343678062116 1.0 0.5086104347367838 154 P42892,P01130,P67870,Q14118,Q9Y6N7,P05556,Q13685,P42785,Q07954,P49768,Q13308,P19022,Q08431,O94813,Q9Y4G8,P38571,O60476,P11233,P43121,P06756,P35613,Q15375,P29317,O14786 24 +Neutrophil migration 0.5587791457650697 1.3946580565303963 0.1631189788186613 1.0 0.5092532713190101 16 O94813,P78310,P84095 3 +Negative regulation of cytokine production involved in inflammatory response 0.8867087336782892 1.3928756676689986 0.1636573916119241 1.0 0.5104496548237255 3 Q06481 1 +Cardiac muscle cell action potential involved in contraction 0.5978325206534194 1.391171332916853 0.1641734780086863 1.0 0.5113319783812209 11 Q14126,Q02487 2 +Renal system vasculature morphogenesis 0.8704693998811679 1.3891788570038863 0.1647783692806008 1.0 0.5122021120494862 2 O14786 1 +Myeloid dendritic cell differentiation 0.8704693998811655 1.389178857003877 0.1647783692806037 1.0 0.5122021120494862 2 P49768 1 +Positive regulation of protein phosphorylation 0.4233913962672411 1.3889844143575836 0.1648374894413389 1.0 0.5122021120494862 107 P54619,O00560,Q13526,P67870,Q14118,P05067,Q9Y6N7,P02786,Q9H223,Q96A49,Q99828,P78536,P49768,P08238,P51114,O95429,Q12959,Q02750,O75955,Q9Y4G8,P07900,Q86VI3,Q06787,Q9Y376,Q13177,Q9NWS0,Q8N122,Q15375,Q86Y37,O14786,P23396 31 +Microvillus organization 0.614073205750264 1.3886304312099766 0.1649451587884254 1.0 0.5122021120494862 10 P15311,Q9Y4G8,Q06124,Q6IBS0,Q9P289,Q14651 6 +Regulation of heart rate 0.587967268384269 1.388457053494713 0.1649979135653483 1.0 0.5122021120494862 12 Q02487 1 +Import into cell 0.494240243783019 1.3874942210801584 0.1652911120702038 1.0 0.5123868686134783 33 P05556,Q9UPY5,Q12959,P30825,Q6UWE0,O14656,O75955,Q8TDW0,Q9BXP2,P49768,P08195,Q15043,P11166 13 +Telomerase holoenzyme complex assembly 0.7586206896551689 1.3861768049905656 0.1656929223085641 1.0 0.5130685953253916 4 P08238,P07900,Q15185 3 +Regulation of cell projection size 0.7583948380685765 1.385317087935554 0.1659555309071021 1.0 0.5130685953253916 4 Q14651,Q6IBS0 2 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.7082249474025745 1.3851226196005386 0.1660149764694356 1.0 0.5130685953253916 5 Q16512,Q13309,Q15648 3 +Regulation of transforming growth factor beta activation 0.8692810457516379 1.384475158141627 0.1662130095224068 1.0 0.5130685953253916 2 P06756 1 +Transforming growth factor beta activation 0.8692810457516379 1.384475158141627 0.1662130095224068 1.0 0.5130685953253916 2 P06756 1 +Virion attachment to host cell 0.8692810457516358 1.3844751581416184 0.1662130095224094 1.0 0.5130685953253916 2 Q92692 1 +Adhesion of symbiont to host cell 0.8692810457516358 1.3844751581416184 0.1662130095224094 1.0 0.5130685953253916 2 Q92692 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7577997529791828 1.3830518569507673 0.1666489659217878 1.0 0.5141730290025891 4 Q9UIQ6 1 +Glomerular epithelial cell differentiation 0.7575275777012374 1.3820158016248707 0.1669668493120761 1.0 0.5144299460303686 4 P11047,Q04721 2 +Glomerular epithelium development 0.7575275777012374 1.3820158016248707 0.1669668493120761 1.0 0.5144299460303686 4 P11047,Q04721 2 +Synaptic vesicle priming 0.8680926916221074 1.3797723081857498 0.1676567613740978 1.0 0.5153741636244507 2 Q7L0J3 1 +Negative regulation of mitochondrial fusion 0.882812616463373 1.3788415495438682 0.1679436129358409 1.0 0.5157261190039084 3 P02786 1 +Cytoplasmic translational elongation 0.7065120428189045 1.3783582608841711 0.1680927034980026 1.0 0.5157261190039084 5 O60524,Q9H2P9,P05387,P49588 4 +Actin filament severing 0.6652136343169003 1.3783567852054683 0.1680931588848251 1.0 0.5157261190039084 7 P23528,P60983 2 +Photoreceptor cell maintenance 0.882248549747088 1.3768100828868854 0.1685709726696322 1.0 0.51646942627892 3 P51790 1 +Regulation of camp dependent protein kinase activity 0.7058904118515905 1.3759032494656764 0.1688515890706847 1.0 0.5170865936840291 5 Q9Y4G8 1 +Negative regulation of leukocyte cell cell adhesion 0.5654783125257382 1.3747225069907991 0.1692174907560935 1.0 0.5170865936840291 14 P17931,Q96J02,P10644,P09429 4 +Epithelial cell differentiation 0.4236109273014904 1.3745460134730452 0.1692722355963793 1.0 0.5170865936840291 109 O14773,Q9P287,P17931,P07602,Q14517,P80723,Q04721,Q13308,Q6YHK3,P19022,Q13510,Q02750,Q9Y4G8,P11047,O95747,Q9BRX2,Q14651,Q15648,P09960,Q9NWS0,O43598,Q9Y624,P43034,P06493,P07437,Q15382,P29317,O14786 28 +Vesicle tethering to golgi 0.7552819499243563 1.3734676440813205 0.1696070132745708 1.0 0.5170865936840291 4 Q15643 1 +Acrosome assembly 0.8812310388721043 1.3731457913976135 0.1697070279488013 1.0 0.5170865936840291 3 Q92692 1 +Translational termination 0.677293259925596 1.3712190258455967 0.1703066889508235 1.0 0.5176882624392409 6 P15170,P61221,P63241 3 +Non motile cilium assembly 0.5595955707304507 1.3704487752188326 0.1705468553057745 1.0 0.5180509001367113 15 Q9P2S5,Q15691,Q15555,Q9UHD8,O15078,Q16181,Q15154,Q8WXW3,Q14203,Q9Y366,P27816 11 +Response to estrogen 0.564618670612822 1.3703313279737408 0.1705834979775184 1.0 0.5180509001367113 14 P22466 1 +Positive regulation of pathway restricted smad protein phosphorylation 0.8797891424887194 1.3679537368469932 0.1713265576384275 1.0 0.5195878728195372 3 O00560 1 +Water homeostasis 0.6439008607182769 1.3662302034197606 0.1718667202940107 1.0 0.5198938947488584 8 Q96PU5,P04062 2 +Cell volume homeostasis 0.6758317109051115 1.365308860550257 0.1721559952721756 1.0 0.5201392891489797 6 P51790 1 +Regulation of neurotransmitter uptake 0.7530850497101191 1.3651050591116187 0.1722200321931404 1.0 0.5201392891489797 4 P05556,O75955 2 +Endochondral bone morphogenesis 0.6614167025216715 1.362679181291239 0.1729836418407599 1.0 0.5212489216804944 7 Q15643,O75844 2 +Negative regulation of actin filament bundle assembly 0.6245535755909652 1.3618331612007244 0.1732505436517879 1.0 0.5215821737359752 9 P07737,P16949,Q9Y624,Q13177 4 +Regulation of alpha beta t cell activation 0.6245519403226101 1.3618259500354857 0.1732528199472645 1.0 0.5215821737359752 9 P04439,P09429 2 +Regulation of actin filament bundle assembly 0.5136772817054225 1.3593992982410443 0.1740200933718254 1.0 0.5226959699542776 25 P35080,O95429,P63000,Q08722,Q9Y624,P07737,Q9Y6W5,Q13177,P16949,O14786 10 +Purine containing compound salvage 0.6417042910389626 1.3568585805740307 0.1748261497052472 1.0 0.5230547062878157 8 Q9NRG1,P07741,P00491,P00492,Q13126 5 +Pericyte cell differentiation 0.8621509209744543 1.3562717562604714 0.1750127184192447 1.0 0.5230547062878157 2 P29317 1 +Nephric duct development 0.8621509209744542 1.3562717562604714 0.1750127184192447 1.0 0.5230547062878157 2 Q15375 1 +Nephric duct morphogenesis 0.8621509209744542 1.3562717562604714 0.1750127184192447 1.0 0.5230547062878157 2 Q15375 1 +Mesenchyme morphogenesis 0.8621509209744538 1.3562717562604685 0.1750127184192456 1.0 0.5230547062878157 2 Q9Y6N7 1 +Metanephric glomerulus development 0.8621509209744529 1.3562717562604658 0.1750127184192464 1.0 0.5230547062878157 2 P11047 1 +Hypotonic response 0.8621509209744512 1.3562717562604587 0.1750127184192487 1.0 0.5230547062878157 2 Q9Y376 1 +Cellular hypotonic response 0.8621509209744512 1.3562717562604587 0.1750127184192487 1.0 0.5230547062878157 2 Q9Y376 1 +Ventricular septum morphogenesis 0.7506215546217692 1.3557279540325575 0.1751857417565705 1.0 0.5230547062878157 4 O94813 1 +Autophagosome maturation 0.5207722751322931 1.355370931028904 0.175299406324211 1.0 0.5230547062878157 23 Q9Y3E7,Q13137,P13473,Q9UEU0 4 +Membrane repolarization 0.6595491880516346 1.3549654962105544 0.1754285503584811 1.0 0.5230547062878157 7 O75844 1 +Nitrogen compound transport 0.3360935697322399 1.3541240820262304 0.1756967943300658 1.0 0.5230547062878157 626 Q06481,P50897,P02786,P07602,Q9NPF0,Q14108,Q99523,Q07954,P22466,P08183,P13473,P10619,O43772,Q15904,Q7L0J3,O43731,Q99595,O60830,P27105,Q96QD8,Q16850,A6NIH7,Q9H2J7,P55786,P08195,Q9NV96,O95219,P30825,O15127,P20645,O00170,O00400,Q4J6C6,P05556,Q9UEU0,Q13438,Q9H173,Q92688,Q96ED9,P49321,O15260,P33527,P67809,Q10713,O00459,Q32P28,Q8N4H5,Q9C0E2,O95831,Q9Y678,Q9BZH6,Q9UMY4,Q96ST2,Q9ULC3,Q8N3F8,P35606,O60684,Q96L92,Q08722,Q9Y3E7,O00560,Q9H4M9,Q9BSK2,P60520,Q9H6Z4,P49768,O95429,O15400,Q9H814,Q06787,P63241,Q8TD16,P78559,P42566,O75312,Q7Z7H5,P62913,P61970,P43034,Q9Y619,Q9NP58,Q9H9C1,Q96D46,Q14168,Q08J23,P09496,O60725 87 +Glycosyl compound biosynthetic process 0.6587822234498367 1.3517971028714342 0.1764402312034696 1.0 0.5234350584735675 7 Q9NRG1,P00491,P00492,P07741 4 +Nucleobase containing small molecule biosynthetic process 0.6587822234498367 1.3517971028714342 0.1764402312034696 1.0 0.5234350584735675 7 Q9NRG1,P00491,P00492,P07741 4 +Cell fate specification 0.672319905275918 1.3511047025126617 0.1766618953170258 1.0 0.5234350584735675 6 P05556,O14786 2 +Sphingosine biosynthetic process 0.6996091103812159 1.3510927226325171 0.1766657323652132 1.0 0.5234350584735675 5 Q13510 1 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.8603683897801566 1.349226384560681 0.1772642625132094 1.0 0.5242550405979476 2 P23396 1 +Phosphatidylethanolamine metabolic process 0.7486693196288525 1.348297266554937 0.1775627909521142 1.0 0.5242550405979476 4 Q8NCC3 1 +Establishment of endothelial intestinal barrier 0.6214711762018843 1.348236786374951 0.1775822363876944 1.0 0.5242550405979476 9 Q9Y624 1 +Lamellipodium assembly 0.522891952508987 1.3470338440237324 0.1779693328889342 1.0 0.5242550405979476 22 O94813,P29317 2 +Trabecula morphogenesis 0.8597742127153909 1.346878452328374 0.1780193823737192 1.0 0.5242550405979476 2 P62942 1 +Heart trabecula morphogenesis 0.8597742127153909 1.346878452328374 0.1780193823737192 1.0 0.5242550405979476 2 P62942 1 +Isoprenoid metabolic process 0.5029918473693252 1.3465368896197951 0.1781294317526911 1.0 0.5242550405979476 27 P61916,Q9HB40 2 +Cellular lipid catabolic process 0.4387336605788272 1.3464414854376603 0.1781601794312377 1.0 0.5242550405979476 64 Q8NHP8,P04066,Q13510,P01130,Q8NCC3,P06280,P07686,P50897,P17900,Q8WTV0,P06865 11 +Cell differentiation involved in kidney development 0.6573922708929937 1.3460544130728482 0.1782849689598067 1.0 0.5242550405979476 7 P11047,O95747,Q04721 3 +Epithelial cell differentiation involved in kidney development 0.6573922708929937 1.3460544130728482 0.1782849689598067 1.0 0.5242550405979476 7 P11047,O95747,Q04721 3 +Positive regulation of exocytosis 0.543969798012147 1.3457206671756123 0.178392618605498 1.0 0.5243371962408249 17 P11279,O95219 2 +Branching involved in salivary gland morphogenesis 0.8734026745913822 1.3449656288793643 0.1786363344670973 1.0 0.5248190299797081 3 Q14118,O14786 2 +Neuromuscular junction development 0.5878855194255765 1.3443398222005964 0.1788385238278862 1.0 0.5249850247514363 11 P11047,P05067 2 +Bergmann glial cell differentiation 0.6978887897710386 1.3442967265063093 0.1788524537044646 1.0 0.5249850247514363 5 Q02750,P08670,P28482,Q06124 4 +Lymphocyte anergy 0.8588829471182454 1.3433570586485253 0.1791563844268171 1.0 0.5254082464376296 2 P01889 1 +T cell tolerance induction 0.8588829471182454 1.3433570586485253 0.1791563844268171 1.0 0.5254082464376296 2 P01889 1 +Quaternary ammonium group transport 0.872861438692239 1.343018159812317 0.1792660936915606 1.0 0.5254791718172568 3 O43772 1 +Connective tissue development 0.5024092529828452 1.3427889031836782 0.179340337599535 1.0 0.5254791718172568 27 O75844,Q15643,Q15043,Q92896 4 +Developmental growth 0.4273764222847856 1.340631924169163 0.1800399869647555 1.0 0.5270596503133788 118 O60271,Q9UJU6,Q14118,A0MZ66,P61201,P05067,Q99538,P07602,P05556,Q9BRT9,Q9UIW2,P80723,Q04721,Q13740,P08238,Q13308,Q14247,O94813,Q8N0X7,Q7Z4V5,P07900,P11047,Q9BRX2,Q6IBS0,Q96PU5,Q99956,Q14651,Q15648,P10644,O75312,Q9BZH6,P43034,P06493,Q15056,Q15375,P52294,O75844,Q92541,O14786 39 +Inner ear receptor cell stereocilium organization 0.6694171706677732 1.3393609636014916 0.1804531910864066 1.0 0.5275583526677932 6 Q14651,Q15643,O95487,O14745 4 +Fatty acid derivative metabolic process 0.5248114419105449 1.3391214395743674 0.1805311419664339 1.0 0.5275583526677932 21 Q9UMR5,P50897 2 +Positive regulation of neuron apoptotic process 0.6190763925522301 1.3376685692046288 0.1810045011942374 1.0 0.5281271116567449 9 Q15375 1 +Protein neddylation 0.6685856507211003 1.335996384037947 0.1815504552017777 1.0 0.5289599546259381 6 Q8TBC4,Q13564,P62913 3 +Myeloid dendritic cell activation 0.8707280832095101 1.3353431345368345 0.1817640671299558 1.0 0.5289599546259381 3 P49768,P09429 2 +Pulmonary valve morphogenesis 0.8707280832095099 1.3353431345368338 0.181764067129956 1.0 0.5289599546259381 3 O94813,Q9Y6N7 2 +Pulmonary valve development 0.8707280832095099 1.3353431345368338 0.181764067129956 1.0 0.5289599546259381 3 O94813,Q9Y6N7 2 +Regulation of response to cytokine stimulus 0.5055820210841486 1.3349420297298549 0.1818953203654412 1.0 0.5289599546259381 26 P78536,O94813,P43034,Q9Y3Z3,Q9Y6N7,P08238,Q8TCT8,Q7Z739 8 +Dendrite self avoidance 0.8698452137036589 1.3321674722327292 0.1828051626884328 1.0 0.5311362014860915 3 Q6PCB8 1 +Muscle cell differentiation 0.4379865586636867 1.3300914415404244 0.1834881450258925 1.0 0.5320934650899691 63 P05556,Q99523,P19022,Q53EL6,O75179,Q8IV08,Q7Z4V5,P67809,O75844,P78310,P10644,Q9H4M9 12 +Mesoderm morphogenesis 0.5846373639760027 1.3290262029153994 0.1838393252205665 1.0 0.5322601590232776 11 P05556,P29317 2 +Regulation of cellular component size 0.4032914612855889 1.3272280691600054 0.1844332498999898 1.0 0.5323200182968539 90 Q9UJU6,P47756,A0MZ66,P62993,Q9BXP2,P08238,Q96B36,O15143,O95429,Q14247,Q12959,O94813,Q8N0X7,Q86VI3,P51790,Q14651,Q8N122,P43034,Q15375,Q9UQB8,O14786 21 +Forebrain neuron development 0.7431239870993491 1.3271930157718772 0.1844448421527531 1.0 0.5323200182968539 4 O14786 1 +Forebrain neuron differentiation 0.7431239870993491 1.3271930157718772 0.1844448421527531 1.0 0.5323200182968539 4 O14786 1 +Microtubule polymerization or depolymerization 0.4718330677061351 1.327003893838138 0.1845073946057809 1.0 0.5323200182968539 38 Q15691,O15344,Q13526,Q16512,P23258,P16949,Q99828,Q66K74,P04350,P46821,Q96P70,Q02790,Q15555,P63000,Q08379,Q7Z460,P78559,P29372,P36405,Q96CW5,Q14203,P23396 22 +Cerebellar cortex formation 0.6926998029406815 1.323796878452203 0.1855705131355893 1.0 0.5346836773569456 5 Q02750,P04062,Q06124 3 +Regulation of protein polyubiquitination 0.6337476668228568 1.3228880306076105 0.1858726163533692 1.0 0.5350853699660669 8 Q13309,P61088 2 +Retina development in camera type eye 0.5276534022563841 1.322240775833201 0.1860879869727529 1.0 0.5352572397110021 19 P54802,P11047,Q07812,P49768,Q15648,O14786 6 +Synapse maturation 0.7414545250357816 1.3208404673198255 0.1865545633631762 1.0 0.5359477324168763 4 P07737,Q12834 2 +Cardiac muscle cell contraction 0.56429389673385 1.3189696997531497 0.1871792424956715 1.0 0.5372011593091306 13 Q14126,Q02487 2 +Positive regulation of protein localization to cell surface 0.6639797395264617 1.3173563319015058 0.1877192110826806 1.0 0.5373441995221381 6 P78559,O94898 2 +Skin morphogenesis 0.8653349418149259 1.3159497846370274 0.1881908974560764 1.0 0.537845004437564 3 P04062 1 +Response to l glutamate 0.739697399285135 1.3141549988944206 0.1887940488777277 1.0 0.5390135648948321 4 O95831 1 +Hypothalamus development 0.6624798857871927 1.3112854623794885 0.1897613380546676 1.0 0.5406020275979229 6 O14786 1 +Sensory organ morphogenesis 0.4831818130644835 1.310963380795018 0.189870135723432 1.0 0.5406778150600589 33 P54802,Q9P273,Q14517 3 +Stress granule assembly 0.5425812936617492 1.3084508837823592 0.1907204234658559 1.0 0.5416941838479113 16 Q9Y520,P05198,P62266,Q14157,Q99700,Q9BYJ9,Q13283,O75534,Q7Z739 9 +Auditory receptor cell development 0.6887533845254569 1.3082058448828031 0.1908035001483141 1.0 0.5416941838479113 5 Q14651,P43034,O95487 3 +Establishment or maintenance of bipolar cell polarity 0.5250190371329693 1.307260961988865 0.1911240976170023 1.0 0.5419826048823073 19 Q12959,Q13418,Q14517,Q13308,Q14168 5 +Positive regulation of apoptotic signaling pathway 0.4886595629971002 1.3054888507245797 0.1917264411655947 1.0 0.5425496868852987 30 Q9Y3D6,Q9NQX7,P63241,Q13177,P53634,P23396 6 +Renal system vasculature development 0.8624071322436855 1.3054276637283009 0.1917472636358559 1.0 0.5425496868852987 3 Q04721,O14786 2 +Myoblast fusion 0.6876973626085121 1.3040339658570057 0.1922220017376861 1.0 0.5436097710363281 5 P05556,O75955,Q9H4M9 3 +Sensory perception of light stimulus 0.5468155708575716 1.303739982535963 0.1923222521384395 1.0 0.5436595507377118 15 O43924,P50897 2 +Regulation of non motile cilium assembly 0.6462859632206308 1.3001411039510948 0.1935526120358526 1.0 0.5458849803432874 7 Q9P2S5,Q15555,Q16181,Q9UHD8,P27816 5 +Lysosomal membrane organization 0.8478906714200858 1.299981156381706 0.193607427658998 1.0 0.5458849803432874 2 Q9Y3E7 1 +Skeletal system morphogenesis 0.514768227100326 1.2987766054222794 0.194020605488254 1.0 0.5460111718979078 22 Q15643,Q9ULC3,Q92896,O75844,Q9NX62 5 +Regulation of epithelial cell differentiation 0.5404749754601963 1.2972108431795375 0.194558650866943 1.0 0.5460111718979078 16 Q6YHK3 1 +Regulation of endocytic recycling 0.846405228758172 1.2941280505531796 0.1956211939198886 1.0 0.5460111718979078 2 Q9H4M9 1 +Modulation of age related behavioral decline 0.8592186440948754 1.2939740702259417 0.1956743774850786 1.0 0.5460111718979078 3 P05067 1 +Regulation of tolerance induction 0.8591381872213972 1.2936851315643103 0.1957742031739502 1.0 0.5460111718979078 3 P01889,P09429 2 +Osteoblast proliferation 0.846108140225792 1.2929576933738 0.1960256917482152 1.0 0.5460111718979078 2 P06756 1 +Regulation of osteoblast proliferation 0.846108140225792 1.2929576933738 0.1960256917482152 1.0 0.5460111718979078 2 P06756 1 +Schwann cell differentiation 0.6444791201055411 1.29266803968961 0.1961258961495 1.0 0.5460111718979078 7 P11047,Q14118,Q13418 3 +Regulation of microvillus organization 0.734045336069798 1.2926556889714758 0.1961301696595252 1.0 0.5460111718979078 4 Q14651,Q6IBS0 2 +Cardiac muscle cell action potential 0.5393450907163704 1.2911788346837283 0.1966416725446631 1.0 0.5466591380564216 16 Q14126,Q02487,P78310 3 +Regulation of membrane protein ectodomain proteolysis 0.6843986267400324 1.2910027775871842 0.196702714368627 1.0 0.5466591380564216 5 O43847,O94898 2 +Positive regulation of gtpase activity 0.4444946012184458 1.2903045520244945 0.1969449370383478 1.0 0.546786486215588 48 P05556,Q0IIM8,Q13526,Q86X10,Q9Y4G8,P84095,Q9Y624,P46060,P46108,P29317,P11274,Q9BXI6,Q8TC07,Q9H6U6 14 +Terpenoid metabolic process 0.5219988983022478 1.290071542160813 0.1970258194859577 1.0 0.546786486215588 19 Q9HB40 1 +Imp salvage 0.8452168746286397 1.2894471588397074 0.1972426754869656 1.0 0.546786486215588 2 P07741 1 +Kidney epithelium development 0.5439916793584554 1.288969729750312 0.1974086103122065 1.0 0.5469898225078749 15 Q12959,O94813,P11047,O95747,Q15375,P80723,Q04721 7 +Positive regulation of dendritic cell differentiation 0.8449197860962596 1.2882771613444446 0.1976495003326364 1.0 0.5472533325546036 2 P09429 1 +Multicellular organism growth 0.4841386124086858 1.2879485321319837 0.1977638797790706 1.0 0.5472533325546036 31 Q99538,P05067,O75844 3 +Morphogenesis of a branching structure 0.5160045192931776 1.2875587805732382 0.197899595636845 1.0 0.5472533325546036 21 Q12959,O94813,Q9UIW2,Q14118,P62993,Q15375,P29317,Q15648,O14786 9 +Regulation of neurotransmitter transport 0.5386602078542368 1.2875216683804425 0.1979125220699784 1.0 0.5472533325546036 16 P05556,O14656,O75955,Q06787,Q4J6C6 5 +Response to interleukin 1 0.5332768794676387 1.2875011084179426 0.1979196835128309 1.0 0.5472533325546036 17 P05067,Q08722 2 +Neurotransmitter reuptake 0.6834511250263784 1.2872600539526973 0.1980036617071217 1.0 0.5472554986174145 5 P05556 1 +Ephrin receptor signaling pathway 0.6251959115704385 1.2863423511527947 0.1983236081429493 1.0 0.5474497248696268 8 Q15375 1 +Polyamine biosynthetic process 0.8443256090314961 1.285937440415796 0.1984648957213477 1.0 0.5476099345868395 2 Q96QD8 1 +Establishment of lymphocyte polarity 0.7321813769822847 1.285567751788755 0.1985939573310167 1.0 0.5477362898630725 4 P35579,Q96L92 2 +Oligodendrocyte development 0.6070323357508267 1.2844618667261527 0.1989803980223088 1.0 0.5485721115635991 9 Q92542,Q9NR50,Q96P11,Q13144,P18074 5 +Positive regulation of cell death 0.4256816264772712 1.2833045612086147 0.1993853953150206 1.0 0.5490402704444038 123 P05556,Q9NQX7,Q07954,P22466,P09429,Q53EL6,O94813,Q9Y4G8,P63241,Q15375,P11717,P49768,P53634,O95831,P23396 15 +Negative regulation of antigen receptor mediated signaling pathway 0.7314493923138999 1.2827846274016 0.1995675412940969 1.0 0.5490402704444038 4 P15311,P17931 2 +Negative regulation of t cell receptor signaling pathway 0.7314493923138999 1.2827846274016 0.1995675412940969 1.0 0.5490402704444038 4 P15311,P17931 2 +Negative regulation of extrinsic apoptotic signaling pathway 0.5086703040918168 1.2823437721981257 0.199722079240507 1.0 0.5492357179113943 23 P17931,O14786,P26583,P06756 4 +Regulation of response to extracellular stimulus 0.681298710285061 1.278758339848126 0.200982168492062 1.0 0.5505894444500024 5 P80303,Q9UMX5 2 +Cardiac muscle contraction 0.5144706320612275 1.2785619396818315 0.2010513599223025 1.0 0.5505894444500024 21 Q14126,P10253,Q02487 3 +Regulation of neuron differentiation 0.5258551336103053 1.277924753609587 0.2012759590933512 1.0 0.5509751389579961 18 O60271,P06730,P05067 3 +Regulation of bmp signaling pathway 0.5648795366240352 1.276666455139443 0.2017200291456005 1.0 0.5509754131485531 12 Q9C0C9,Q8N0X7,Q92859,Q9BRX2,Q04721 5 +Protein kinase b signaling 0.4860627136692238 1.276381919156834 0.2018205445880108 1.0 0.5509754131485531 29 P05556,O95429,Q12959,Q13641,P07900,Q14118,P29317,P08238,Q99828 9 +Regulation of t cell chemotaxis 0.8542717258324948 1.276216009526525 0.2018791708275036 1.0 0.5509754131485531 3 P78536 1 +Regulation of lymphocyte chemotaxis 0.8542717258324948 1.276216009526525 0.2018791708275036 1.0 0.5509754131485531 3 P78536 1 +Positive regulation of lymphocyte chemotaxis 0.8542717258324948 1.276216009526525 0.2018791708275036 1.0 0.5509754131485531 3 P78536 1 +Positive regulation of ubiquitin protein transferase activity 0.5723943069987254 1.271228874130002 0.2036472372609781 1.0 0.5540080755594351 11 Q16763,P61088,Q13526,Q12834,Q96GX5,P63208,Q9UNE7 7 +Positive regulation of intracellular signal transduction 0.4461967957140171 1.2701829453792033 0.2040194711710805 1.0 0.5545620170923008 155 O60271,Q9Y3D6,P23396,Q9UMX5,P19525,O00560,Q9Y6K9,P05067,Q9Y6N7,P02786,P62942,Q99828,P05556,P61088,O75179,P60866,Q04721,Q07812,P49768,P08238,O94992,P19022,O95429,Q02750,Q13641,Q9Y4G8,P07900,Q86VI3,P63241,P29372,Q9NWS0,P06756,Q8N122,P09429,Q13418,Q53EL6,Q7Z7H5,O43657,Q9Y624,Q92734,Q15382,Q969S3,O14786 43 +Positive regulation of cell development 0.4279685237698494 1.2696428603551728 0.2042118748854384 1.0 0.554774311547667 66 Q13418,Q02750,Q14444,Q9UJU6,O94813,Q9UIW2,Q9Y624,P43034,Q14118,P46108,A0MZ66,O14786,Q6IBS0,Q15382,Q9Y6N7,Q9UQB8,P55209,Q99828 18 +Cytokine mediated signaling pathway 0.4410502365461214 1.269490298544295 0.2042662484901869 1.0 0.554774311547667 50 P78536,Q06481,O94813,P43034,P67870,P63241,O95747,Q9Y3Z3,Q9Y6N7,P08238,Q8TCT8,Q7Z739 12 +Regulation of developmental growth 0.4376811028291666 1.2662363515796 0.2054284765685214 1.0 0.5567814251618188 55 O60271,Q14247,Q14651,Q9UJU6,Q8N0X7,P43034,P06493,Q99956,A0MZ66,Q15375,P05067,P80723,Q6IBS0,O75844,Q96PU5,Q99538,O14786 17 +Regulation of biomineralization 0.6380262737421538 1.265973913492479 0.2055224218725984 1.0 0.5568066272973444 7 O95747,O75844 2 +Vascular endothelial growth factor signaling pathway 0.7266036627782058 1.2643657490628644 0.2060987804878158 1.0 0.5576790530846781 4 O14786,Q9Y6N7 2 +Protein import into mitochondrial matrix 0.6021714661976079 1.2629665020585308 0.2066012184502461 1.0 0.5586734149748768 9 Q99595 1 +Granulocyte migration 0.5172253477702315 1.2628693870323782 0.2066361232340947 1.0 0.5586734149748768 19 O94813,P78310,P84095 3 +Modification of postsynaptic actin cytoskeleton 0.7261458922350776 1.2626262620150164 0.2067235252546113 1.0 0.5586800941351 4 P07737,Q9UQB8 2 +Modification of postsynaptic structure 0.6501362528326288 1.261313222047264 0.2071960193209712 1.0 0.5592677123895562 6 P07737,Q9UQB8 2 +Regulation of dendrite extension 0.8491435587146602 1.2578245069511318 0.208455230634974 1.0 0.5612846938669093 3 Q96PU5 1 +Regeneration 0.47055566583057 1.2563057454461863 0.2090051396403125 1.0 0.5621522854025638 35 O94898,P10586,Q02750,O14744,Q7Z4V5,Q14118,P11047,P06493,P52294,P11717,Q15648 11 +Tangential migration from the subventricular zone to the olfactory bulb 0.8487124723060335 1.2562793308363165 0.2090147130596378 1.0 0.5621522854025638 3 O94813 1 +Lamellipodium organization 0.4889756245683178 1.2560971334246556 0.2090807553295062 1.0 0.5621522854025638 27 P05556,Q14247,Q13596,P63000,O94813,O60749,P47756,Q9Y6W5,Q6IBS0,P29317 10 +Branching morphogenesis of an epithelial tube 0.5376631451987677 1.2558341579792072 0.2091761043883955 1.0 0.5621522854025638 15 O94813,O14786,P29317 3 +Regulation of cation transmembrane transport 0.4383414788529072 1.2557551908303384 0.2092047422720395 1.0 0.5621522854025638 52 P05556,P22466,Q06787,P27105,P05067,Q96PU5,P62942 7 +Signal release 0.4339775956484806 1.2537786437217238 0.2099224737043243 1.0 0.5631606982165765 58 Q7L0J3,P22466,O95219,P50897 4 +Negative regulation of lymphocyte differentiation 0.7235767488978027 1.2528655979967596 0.2102546236329794 1.0 0.5634589899469831 4 P09429 1 +Cellular hormone metabolic process 0.5269124607316434 1.252766659498142 0.210290638540566 1.0 0.5634589899469831 17 P42892 1 +Actin filament bundle organization 0.4406463267321519 1.250140624720501 0.2112481818953784 1.0 0.5644153292070672 45 P05556,P35080,O95429,Q05682,P63000,Q08722,P15311,Q9Y624,Q9UQB8,P07737,A0MZ66,Q9Y6W5,Q13177,Q14651,P16949,O14786 16 +Inorganic ion import across plasma membrane 0.5990195501657196 1.2490233439278384 0.2116565358186342 1.0 0.5648181308782863 9 Q9BXP2 1 +Negative regulation of sodium ion transmembrane transport 0.7223687977338669 1.248277503437464 0.2119294497504766 1.0 0.5651002046685774 4 Q96PU5,O95747 2 +Regulation of bone mineralization 0.7223654864699598 1.2482649274934134 0.2119340536511675 1.0 0.5651002046685774 4 O75844 1 +Regulation of leukocyte degranulation 0.5830761949474244 1.2472281240483507 0.2123138634600125 1.0 0.5656148096017499 10 P11279 1 +Striated muscle contraction 0.4990455546834952 1.2450717895380243 0.2131053627404999 1.0 0.5666820955916209 24 Q14126,P10253,Q02487 3 +Regulation of dendritic cell differentiation 0.8451708766716199 1.2435902824512293 0.2136503944548637 1.0 0.5676059348643352 3 P01889,P09429 2 +Negative regulation of smooth muscle cell differentiation 0.72063760672942 1.241703370901178 0.2143460257913985 1.0 0.568994413904689 4 Q53EL6 1 +Xenophagy 0.670808993641761 1.2373414849089666 0.2159603326564334 1.0 0.5714348625156955 5 Q13137 1 +Positive regulation of dendritic spine morphogenesis 0.6132257923434821 1.235149723330948 0.2167747867209102 1.0 0.5731288372388053 8 Q14444,Q9UQB8,P43034 3 +Tolerance induction 0.7182942730674062 1.232807342646652 0.2176476512232235 1.0 0.5749362975896909 4 P01889,P09429 2 +Positive regulation of transmembrane transport 0.4759674503953251 1.2323436997590895 0.2178207222485559 1.0 0.5749362975896909 31 P08183,P22466 2 +Endothelium development 0.4893301911488517 1.231736063457232 0.2180476936524777 1.0 0.5751010297617536 26 Q9Y624,Q9Y4G8,O14786 3 +Regulation of antigen receptor mediated signaling pathway 0.5946069270770461 1.2294980238675706 0.2188851383084582 1.0 0.5759842737300946 9 P15311,P17931,Q92692,Q9Y6K9,P51452,P23396 6 +Cranial nerve development 0.7169892745790301 1.2278545797773095 0.2195015625012497 1.0 0.5765856695049416 4 O14786 1 +Polyamine metabolic process 0.8405266742181261 1.2269660833509817 0.2198353388747937 1.0 0.5765856695049416 3 Q96QD8 1 +Spermidine metabolic process 0.8405266742181261 1.2269660833509817 0.2198353388747937 1.0 0.5765856695049416 3 Q96QD8 1 +Manganese ion transmembrane transport 0.8401188707280838 1.2255072038504875 0.2203841775211075 1.0 0.5771422512879493 3 Q9HC07,Q15043 2 +Manganese ion transport 0.8401188707280838 1.2255072038504875 0.2203841775211075 1.0 0.5771422512879493 3 Q9HC07,Q15043 2 +Thymus development 0.6107677858938299 1.2246346133673898 0.2207129203111886 1.0 0.5771422512879493 8 Q02750,P49768,O75844 3 +Positive regulation of dendrite morphogenesis 0.59332113751456 1.223807662444717 0.2210247930804385 1.0 0.5771422512879493 9 Q14444,Q9UQB8,P43034 3 +Negative regulation of membrane potential 0.7159114174650395 1.2237646725687596 0.2210410147341832 1.0 0.5771422512879493 4 O75915,Q07812 2 +Cellular response to insulin like growth factor stimulus 0.8395245170876675 1.2233812209025952 0.2211857428402812 1.0 0.5771422512879493 3 P46108,Q9BSK2 2 +Regulation of anatomical structure morphogenesis 0.4427968655346649 1.2209939303695667 0.2220883179070569 1.0 0.578762547553062 157 O60271,Q9Y3D6,P15311,Q9UJU6,P84095,P47756,A0MZ66,Q14118,Q16512,P46934,O43707,Q9Y6N7,P02786,Q5VSL9,Q99828,P05556,P23528,P35579,P04792,P46821,Q96TA1,Q9UIW2,O14964,P49768,Q13308,P19022,Q12959,P63000,Q02750,O94813,Q8N0X7,Q9Y4G8,Q05086,O95747,Q6IBS0,P07686,Q13177,Q96PU5,P11233,O00429,Q99536,Q13418,Q14444,Q9Y624,P43034,P46108,Q15375,P11274,P29317,Q16181,O75844,Q9UQB8,Q9UEE9,O14786 54 +Regulation of protein localization to synapse 0.827688651218066 1.2205903253377637 0.2222411712160408 1.0 0.578762547553062 2 Q14118 1 +Smooth muscle tissue development 0.8276886512180639 1.2205903253377557 0.2222411712160439 1.0 0.578762547553062 2 O95747 1 +Regulation of nuclease activity 0.6093144998850355 1.2184174357348143 0.2230653826246609 1.0 0.578762547553062 8 P09429,P23396 2 +Regulation of camp mediated signaling 0.8270944741533016 1.2182630219263495 0.2231240373568979 1.0 0.578762547553062 2 Q9Y4G8 1 +Glycoprotein metabolic process 0.4211945052379675 1.2180948728136929 0.2231879220530011 1.0 0.578762547553062 67 Q9NQX7,Q15643,Q92542,O15118,Q7LGA3,O43505,Q9HC07,O00754,Q10472,O60476,Q9NX62 11 +Positive regulation of hormone secretion 0.5091154519625606 1.2165704878625956 0.2237676770316272 1.0 0.578762547553062 19 P22466 1 +Cardiac atrium development 0.8265002970885333 1.2159362129528422 0.2240092218456655 1.0 0.578762547553062 2 Q04721 1 +Cardiac atrium morphogenesis 0.8265002970885333 1.2159362129528422 0.2240092218456655 1.0 0.578762547553062 2 Q04721 1 +Atrial septum development 0.8265002970885333 1.2159362129528422 0.2240092218456655 1.0 0.578762547553062 2 Q04721 1 +Atrial septum morphogenesis 0.8265002970885333 1.2159362129528422 0.2240092218456655 1.0 0.578762547553062 2 Q04721 1 +Establishment of centrosome localization 0.713787195796025 1.2157065775422484 0.2240967176372224 1.0 0.578762547553062 4 Q12959,P43034 2 +Adhesion of symbiont to host 0.7130454773782963 1.212893638011284 0.2251704883249436 1.0 0.5806092265379517 4 Q8WTV0,Q92692 2 +Microtubule anchoring at centrosome 0.8365781801574916 1.2128469823688246 0.2251883288993759 1.0 0.5806092265379517 3 Q14203 1 +Plasma membrane raft organization 0.8256090314913862 1.2124469366482264 0.2253413431668274 1.0 0.5806092265379517 2 Q9UNF0 1 +Plasma membrane raft assembly 0.8256090314913862 1.2124469366482264 0.2253413431668274 1.0 0.5806092265379517 2 Q9UNF0 1 +Cytoplasmic microtubule organization 0.5193017661508214 1.2111621735429303 0.2258332568036536 1.0 0.581412234559024 17 Q12959,Q96ED9,Q9H2G2,P15311,Q99828,P43034,P23258,Q15154,Q96CW5,Q14203,Q03001 11 +Regulation of water loss via skin 0.8359073694169995 1.2104497102294491 0.2261063768868676 1.0 0.581412234559024 3 P04062 1 +Positive regulation of tau protein kinase activity 0.8250148544266203 1.2101213839696876 0.2262323188140189 1.0 0.581412234559024 2 P08238 1 +Positive regulation of rho protein signal transduction 0.663759221378908 1.209529099175373 0.2264596385800645 1.0 0.5814408675174335 5 Q9Y624 1 +Negative regulation of response to cytokine stimulus 0.6241601055895435 1.2086036013696495 0.226815172160764 1.0 0.5818994549428651 7 O94813,Q9Y3Z3,Q9Y6N7 3 +Lymphocyte activation involved in immune response 0.4810606758842585 1.204797557447998 0.2282814631671033 1.0 0.5851726530173813 27 P49768,P09429,P11279,P02786,P13051 5 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.588751125159335 1.2035804604811646 0.2287517754271748 1.0 0.5859537300467119 9 O43657 1 +Regulation of organic acid transport 0.5578630314131361 1.2025155870664257 0.2291638307447998 1.0 0.5867807234874634 11 P05556,Q7L0J3 2 +Regulation of extent of cell growth 0.4884282869961152 1.2016987605195657 0.2294802615518159 1.0 0.5873623192559708 25 Q14247,Q9UJU6,Q8N0X7,P43034,A0MZ66,Q15375,O14786 7 +Regulation of dendritic spine development 0.522499928019568 1.2010652482973765 0.229725892104128 1.0 0.5877623174877303 16 Q14444,P43034,Q06787,P49768,Q9UQB8 5 +Negative regulation of innate immune response 0.5492521324638117 1.2007546432203102 0.2298463907550016 1.0 0.5878419744892694 12 P04439,P01889,Q9Y3Z3,Q7Z739 4 +Respiratory gaseous exchange by respiratory system 0.5574335800903589 1.2004836988514067 0.2299515398158729 1.0 0.5878823275976727 11 P10253 1 +Epidermal cell differentiation 0.4727718221374962 1.1985285051346424 0.2307113326642949 1.0 0.5888800584581116 30 Q6YHK3,Q13510 2 +Positive regulation of ion transport 0.4342493771842136 1.1980931463525533 0.2308807567087032 1.0 0.5888800584581116 45 P08183,O95219,P22466 3 +Vascular endothelial growth factor receptor signaling pathway 0.6045278078733202 1.1979399832621034 0.2309403826125129 1.0 0.5888800584581116 8 P04792,Q96TA1,P46934,Q13177,O14786 5 +Polyol metabolic process 0.4913902346138588 1.1978678614752534 0.2309684631836315 1.0 0.5888800584581116 24 Q13510,P04062,Q9NX62 3 +Positive regulation of protein dephosphorylation 0.5485407602432628 1.197296263337491 0.2311911003619238 1.0 0.5892193173888938 12 Q86XL3,Q13526,P04062 3 +Response to purine containing compound 0.5217291725788221 1.1969350640135554 0.2313318658982601 1.0 0.5893497342675272 16 P05067,Q9Y4G8 2 +Regulation of protein lipidation 0.7083540307639633 1.1951107518570818 0.2320437617345085 1.0 0.5904773170946218 4 P04062 1 +Urogenital system development 0.4331459943588225 1.1938370683049742 0.2325417084783896 1.0 0.5914239195778883 47 O94813,Q15375,O75844,P07602,O14786 5 +Regulation of lipid catabolic process 0.6033922370193577 1.1930822169649693 0.2328371752927931 1.0 0.5915808957419827 8 P01130 1 +Multicellular organismal movement 0.571087859907846 1.1924048739015911 0.2331025301351363 1.0 0.5917147830099277 10 P10253,P78559 2 +Purine nucleotide salvage 0.6593519278113036 1.1921544681470857 0.2332006829757347 1.0 0.5917147830099277 5 P07741 1 +Response to calcium ion 0.4865730562429419 1.190054807876595 0.2340248510062039 1.0 0.5918552364163051 25 Q99538 1 +Gastrulation 0.4655528973883654 1.188104073739897 0.2347924095965585 1.0 0.5931108813497472 33 P05556,P07942,P29317,P10644,P06756 5 +Protein deneddylation 0.5699330044197456 1.187122216484804 0.2351794163365959 1.0 0.5931108813497472 10 Q7L5N1,O14656,P61201,Q9H9Q2,Q92905 5 +Regulation of collateral sprouting 0.8293674131862796 1.1871010581735115 0.2351877610183881 1.0 0.5931108813497472 3 Q15375 1 +Endoderm formation 0.5849345767232019 1.186686642224018 0.2353512458679518 1.0 0.5931108813497472 9 P06756 1 +Endodermal cell differentiation 0.5849345767232019 1.186686642224018 0.2353512458679518 1.0 0.5931108813497472 9 P06756 1 +Negative regulation of muscle cell differentiation 0.5544015830604061 1.1861371703265138 0.2355681335613018 1.0 0.5931108813497472 11 P67809,Q53EL6 2 +Transmission of nerve impulse 0.6182543792845984 1.1841755235796207 0.2363435889889427 1.0 0.5931583854899904 7 P04062,Q06787 2 +Skeletal system development 0.4265654926918836 1.1827355249472895 0.2369139802999396 1.0 0.5943631435594976 57 Q15643,Q04721,P49768,Q15043,Q9NX62,Q12959,O96028,Q92896,O95747,Q15904,P07686,Q32P28,Q15648,O43252,O60256,Q9ULC3,P43034,O75844,P29317 19 +Response to ether 0.7047428089904577 1.181434210057574 0.2374302745444749 1.0 0.5950907493892835 4 Q6PKG0 1 +Cilium organization 0.4211644695123048 1.1795718227046654 0.2381705552789437 1.0 0.5950907493892835 63 Q15019,Q15691,Q96J42,Q9BXI6,Q8WXW3,Q8TC07,Q4KMP7,Q9H223,Q9H4M9,Q96FJ2,P50395,Q9UHD8,Q15555,P42858,Q9Y366,Q9P2S5,Q01968,Q9BZH6,Q8IVD9,Q9ULC3,Q16181,Q96PY6,Q92692,P36405,Q15154,A6NIH7,Q14203 27 +Sensory perception 0.4598206577386298 1.1794926500786485 0.2382020616917761 1.0 0.5950907493892835 35 Q14108,O43924,O94898,P07686,P50897 5 +Positive regulation of smooth muscle cell migration 0.7035694095639782 1.1769926504240853 0.2391984397376605 1.0 0.5950907493892835 4 O14786 1 +Negative regulation of protein kinase b signaling 0.5826849944984516 1.1767288846190735 0.2393037351259874 1.0 0.5950907493892835 9 Q99828,P29317,Q12959,Q14118 4 +Outflow tract morphogenesis 0.5985986205446372 1.172578009506276 0.2409650721963687 1.0 0.5967351762325738 8 O14786 1 +Neural retina development 0.5985581274064147 1.172404822672333 0.2410345641912357 1.0 0.5967351762325738 8 P54802 1 +Positive regulation of protein depolymerization 0.702199741307168 1.1718097207960665 0.2412734590505976 1.0 0.5968897282733971 4 P48681 1 +Regulation of tumor necrosis factor mediated signaling pathway 0.5813107054932032 1.1706457359239388 0.2417412053736769 1.0 0.5973883438808782 9 Q8TCT8 1 +Caveolin mediated endocytosis 0.7013717690171892 1.1686774399669413 0.2425336146668035 1.0 0.5973883438808782 4 Q96PU5,Q9UNF0 2 +Central nervous system maturation 0.814319667260845 1.168353360812154 0.2426642594836769 1.0 0.5973883438808782 2 O75787 1 +Apoptotic process involved in development 0.6271612688578461 1.1683460735133244 0.242667197753942 1.0 0.5973883438808782 6 O75312,O94813 2 +Cell cell recognition 0.5250455641066767 1.1672603382288889 0.2431052504524471 1.0 0.5973883438808782 14 Q12959,O14967,P50991,P17931,Q14157,P04075,P26038,P17987,Q99832 9 +Sterol biosynthetic process 0.4825398556799025 1.1647191201644136 0.244132706858023 1.0 0.5973883438808782 25 Q16850,Q14739,Q9UBM7,Q15392 4 +Positive regulation of signaling 0.4844631770306908 1.1638277767875091 0.2444938130460261 1.0 0.5973883438808782 276 O60271,P42892,P23396,Q9UMX5,Q06481,O95219,Q9H1E3,O00560,Q13526,Q92859,P67870,Q9Y6K9,P05067,Q9Y6N7,P02786,Q99538,P62942,P05556,P78536,P22466,O75179,P49768,P53634,Q9H2V7,Q13308,Q15043,O94992,Q9NQX7,P19022,O95429,Q92542,Q13309,Q13641,Q9Y4G8,Q06787,Q86VI3,P63241,P29372,P06756,P05198,Q8N122,Q9C0C9,P04062,P09429,Q53EL6,Q7Z7H5,O43657,Q9Y624,P43034,Q92692,Q14168,Q92734,Q9UQB8,O14786 54 +Regulation of cellular extravasation 0.8131313131313169 1.1637238990181458 0.2445359209918769 1.0 0.5973883438808782 2 Q08722 1 +Cartilage development involved in endochondral bone morphogenesis 0.6516552536391502 1.1618421030126211 0.245299608334085 1.0 0.5973883438808782 5 O75844 1 +Establishment of epithelial cell polarity 0.5642330507812281 1.161048351890447 0.2456222367069085 1.0 0.5973883438808782 10 Q14517 1 +Transport along microtubule 0.4258295818289505 1.1594505746487016 0.2462725719536342 1.0 0.597467403909141 54 Q9Y678,P11279,P43034,Q14203,P05067,Q8TD16,P78559,Q14168,Q13409 9 +Tooth mineralization 0.8119429590017841 1.1590968685882792 0.2464167021595469 1.0 0.597467403909141 2 P04920 1 +Enamel mineralization 0.8119429590017841 1.1590968685882792 0.2464167021595469 1.0 0.597467403909141 2 P04920 1 +Amelogenesis 0.8119429590017841 1.1590968685882792 0.2464167021595469 1.0 0.597467403909141 2 P04920 1 +Schwann cell development 0.6242142935062098 1.1564353060901629 0.2475031472125788 1.0 0.597856020940841 6 P11047,Q14118 2 +Nucleoside phosphate catabolic process 0.5040555767100477 1.1560926510601657 0.2476432616715334 1.0 0.597856020940841 18 Q9NRG1,O43598,Q9Y3Z3,Q9H773,P13051 5 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.5779755306571973 1.1558838024637068 0.2477286888097776 1.0 0.597856020940841 9 P17931,P26583,Q9UNN5,Q13188,Q12846 5 +Modulation by host of symbiont process 0.4878196151379086 1.1558108960230171 0.2477585152150703 1.0 0.597856020940841 23 P11717,P27105 2 +Proteasome assembly 0.6111967454218016 1.154996570838511 0.2480918307317052 1.0 0.598440800349526 7 Q9BT73,O95456 2 +Cardiac conduction system development 0.8201706163919145 1.154344886206376 0.248358800963149 1.0 0.5988651732901737 3 Q14126 1 +Exocytic process 0.4904839051645441 1.1537447487478611 0.2486048319912484 1.0 0.5992387632240498 22 P49768,Q7L0J3,O95219,Q9UEU0 4 +Neurotransmitter receptor localization to postsynaptic specialization membrane 0.819465607460909 1.1518379501262683 0.2493876699692701 1.0 0.6002459176940573 3 Q14118 1 +Establishment of tissue polarity 0.6103359676328233 1.1514391729958202 0.2495516058945233 1.0 0.6002952715199963 7 Q13308,P43034,O95487,P63000 4 +Regulation of hormone levels 0.4159905151753737 1.1506008185514929 0.2498964960985501 1.0 0.6002952715199963 65 P42892,O95219,P22466,Q9HB40,Q9UBM7,O75844 6 +Leukocyte degranulation 0.5214223843638103 1.148608082521288 0.2507176227539229 1.0 0.600719961622359 14 P11279 1 +Positive regulation of biomineralization 0.81841107267198 1.1480892859930485 0.2509317066682373 1.0 0.600719961622359 3 O95747 1 +Megakaryocyte development 0.6951036304663001 1.1449862022994868 0.2522148730141591 1.0 0.6022030615924279 4 Q15648,Q9Y6W5 2 +Morphogenesis of an epithelium 0.4107455941334575 1.14257885355783 0.2532134894930409 1.0 0.6032735725770456 69 P78536,O94813,Q9UIW2,P43034,P67870,Q14118,P62993,Q14517,O95747,Q15375,Q04721,P29317,P49768,Q13308,P11233,O14786 16 +Regulation of receptor binding 0.6941002710379087 1.1411976285355234 0.2537876909905625 1.0 0.6039853224804344 4 O14786 1 +Negative regulation of p38mapk cascade 0.8071895424836617 1.1406138778805812 0.2540306395214178 1.0 0.6041263726579488 2 Q12959 1 +Intestinal hexose absorption 0.8071895424836618 1.1406138778805812 0.2540306395214178 1.0 0.6041263726579488 2 Q14651 1 +Regulation of extrinsic apoptotic signaling pathway 0.4541340355348461 1.1386621554089749 0.2548440931077345 1.0 0.6056229929417187 35 Q9NQX7,O14786,P06756 3 +Cellular modified amino acid catabolic process 0.5900869744741455 1.136184871731838 0.2558792005872647 1.0 0.6062489930359143 8 Q9UJ14 1 +Positive regulation of dephosphorylation 0.5276229561426232 1.1358265980491948 0.256029142999965 1.0 0.6062489930359143 13 Q86XL3,Q13526,P04062 3 +Microtubule based transport 0.4222937409100609 1.1342460002700898 0.2566913732947997 1.0 0.6067250641513449 55 Q9Y678,P11279,P43034,Q14203,P05067,Q8TD16,P78559,Q14168,Q13409 9 +Fatty acid transmembrane transport 0.6183289248449628 1.13266409050214 0.2573553430619859 1.0 0.6074442364985035 6 O43772 1 +Regulation of protein polymerization 0.4173773493671107 1.1294850865203856 0.2586932572659266 1.0 0.6091316741095554 61 Q15691,Q9NYL9,Q9UJU6,P07737,Q16512,P62993,P47756,P16949,P04350,P46821,O15143,O95429,Q14247,Q12959,Q02790,P63000,O94813,P07900,Q6IBS0,P35080,P36405,Q14203,Q9UQB8,P23396 24 +Central nervous system projection neuron axonogenesis 0.8129980534618624 1.128869510922866 0.258952884198725 1.0 0.6091316741095554 3 O94813 1 +Locomotion 0.4785056610216538 1.1261803505569978 0.2600891889003887 1.0 0.6103698482293103 263 P42892,P13591,Q6PCB8,Q06481,O94898,O00560,Q13526,P26583,Q92859,P84095,P67870,Q14118,P05067,Q9Y6N7,Q99538,P78310,Q9Y2I1,P05556,Q8TEY7,Q13685,P78536,P42785,Q07954,Q14517,Q13740,P49768,Q13308,P19022,P33527,P10586,O94813,Q13641,Q9Y4G8,P11047,P07686,Q8WTV0,Q08722,P43121,P06756,P04062,P09429,P07942,Q9Y624,P35613,Q15375,P29317,O14786 47 +Cell junction organization 0.4221248962118393 1.1248406289000568 0.2606565743560447 1.0 0.6110017609766418 139 Q14126,Q9UJU6,O00560,Q13526,Q14118,P05067,Q99538,P78310,P49768,P19022,P10586,Q13641,Q9Y4G8,P11047,Q14444,Q9Y624,P43034,P07437,Q15375,P29317,Q14203,Q9UQB8,O14786 23 +Regulation of protein exit from endoplasmic reticulum 0.60386225984032 1.124697193264317 0.2607173714808861 1.0 0.6110017609766418 7 Q9NV96 1 +Golgi localization 0.6420749258191881 1.1241774506826891 0.2609377535369137 1.0 0.6110017609766418 5 P48444,Q9Y678 2 +Positive regulation of actin filament bundle assembly 0.5166169359128872 1.123864100057847 0.2610706831904401 1.0 0.6110017609766418 14 P35080,O95429,P63000,P07737,Q08722,O14786 6 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.641964613408263 1.123744261854604 0.2611215333497607 1.0 0.6110017609766418 5 O00560,P78536 2 +Regulation of post translational protein modification 0.8105385679831489 1.120149679332631 0.2626499833364235 1.0 0.6124465049227202 3 Q32P28 1 +Regulation of regulated secretory pathway 0.4786817105020983 1.1192785878709253 0.2630213076212551 1.0 0.6130950253481984 24 P11279,O95219 2 +Sphingoid metabolic process 0.6147738085112789 1.1183165958602967 0.2634318014014298 1.0 0.6133141304248448 6 Q13510 1 +Axis elongation 0.8098520774525588 1.1177173081254967 0.2636877481834159 1.0 0.6135613751505163 3 Q13308 1 +Mammary gland morphogenesis 0.6140135706652566 1.1152497655195697 0.2647434056088495 1.0 0.6149796074498018 6 Q15648,P29317 2 +Regulation of ubiquitin protein transferase activity 0.474447431694242 1.1138023932529586 0.26536397004147 1.0 0.6152358537394527 25 Q16763,P62829,O00429,P61088,P62913,P60866,Q13526,Q12834,Q96GX5,P63208,P46777,P49768,Q9UNE7 13 +Mesonephros development 0.5844996699511055 1.1123116767254433 0.2660041650701241 1.0 0.6163351172353916 8 O95747,O94813,P80723,Q12959 4 +Torc2 signaling 0.8077734303264759 1.1103563533735732 0.26684549836932 1.0 0.6166366397518025 3 Q96A49 1 +Protein localization to cell junction 0.4831602796430909 1.1098313161869848 0.267071721899192 1.0 0.6166366397518025 22 P04792,Q9Y624,Q14118,Q9UQB8,Q13177,P78559,Q14168 7 +Regulation of microvillus length 0.8074294205052011 1.1091387408205555 0.2673703345353626 1.0 0.6171094949381107 3 Q14651,Q6IBS0 2 +Hepatocyte growth factor receptor signaling pathway 0.636764469403057 1.1033382495697857 0.2698803019461193 1.0 0.6199860390032399 5 P16949,O14786,P63000 3 +Regulation of dna ligation 0.8053526460017825 1.101791772785515 0.2705522079443363 1.0 0.6210466310214563 3 P09429 1 +Positive regulation of nuclease activity 0.80529808261281 1.1015988317231675 0.270636116463181 1.0 0.6210466310214563 3 P23396 1 +Proteoglycan metabolic process 0.6106024654680797 1.101495267334638 0.2706811631405466 1.0 0.6210466310214563 6 Q7LGA3 1 +Negative regulation of transforming growth factor beta production 0.7967914438502697 1.1003332790659166 0.2711869373697699 1.0 0.6213401860043011 2 P08238 1 +Transforming growth factor beta1 production 0.7967914438502696 1.1003332790659162 0.2711869373697702 1.0 0.6213401860043011 2 O75787 1 +Regulation of transforming growth factor beta1 production 0.7967914438502696 1.1003332790659162 0.2711869373697702 1.0 0.6213401860043011 2 O75787 1 +Neuronal action potential 0.635898402023627 1.0999426021162977 0.2713571311901011 1.0 0.6215136521478012 5 P04062 1 +Regulation of mammary gland epithelial cell proliferation 0.6356711316488524 1.0990516723783188 0.2717455278915555 1.0 0.6216479745558455 5 Q9Y6N7,Q86VI3 2 +Alpha beta t cell proliferation 0.8044855811194165 1.0987262863528495 0.2718874732809566 1.0 0.6216479745558455 3 P04439 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.6098144588584439 1.0983192864733589 0.2720650930935975 1.0 0.6216479745558455 6 O94992,O95373,O00410 3 +Synaptic signaling 0.3868862220506992 1.0982121043366735 0.2721118819226025 1.0 0.6216479745558455 96 O00560,Q12834,Q14118,P05067,P50897,Q99538,Q4J6C6,P05556,P49768,P19022,Q92542,Q13641,Q9Y4G8,Q06787,P51790,Q7L0J3,P78559,P43034,Q9UNF0,Q14168,Q9UQB8 21 +Negative regulation of proteasomal protein catabolic process 0.4782866503898968 1.0977327643410792 0.2723211983397164 1.0 0.6216479745558455 23 Q96KB5,P62913,P60520,O00560,P54578,Q92530,Q9NZM5,P08238,P78559,Q04323 10 +Inositol phosphate metabolic process 0.5969790849643042 1.096293182347893 0.2729504919904051 1.0 0.6225714831055175 7 Q9NX62 1 +Organophosphate catabolic process 0.4378429334360624 1.0947704101927684 0.2736172328455535 1.0 0.6225714831055175 39 Q8NHP8,P01130,O75874,Q8NCC3,Q9Y3Z3,Q10713,Q9H773,Q8WTV0,P13051,Q9NX62 10 +Regulation of early endosome to late endosome transport 0.5193628678679436 1.094508480151941 0.2737320301885309 1.0 0.6226173217773707 13 Q9Y3E7,P28482,Q9UMY4,Q02750,P15311,P36507,O60493,P26038,P27361 9 +Auditory receptor cell morphogenesis 0.6814094122014241 1.093380563215346 0.2742267438537507 1.0 0.623513641233986 4 Q14651,O95487 2 +Intra golgi vesicle mediated transport 0.4853879558681795 1.0931029191334634 0.2743486144637428 1.0 0.623513641233986 20 Q14746,Q9Y678,Q9UEU0,P60520,P35606,Q8TBA6,P54920 7 +Modification of synaptic structure 0.5961189271556295 1.092746207942426 0.2745052455174253 1.0 0.623513641233986 7 P07737,Q9UQB8 2 +Negative regulation of establishment of protein localization to mitochondrion 0.6804399524375667 1.0897363332071217 0.2758293063808255 1.0 0.6258727759134426 4 O95429,O95817,P31689 3 +Leukotriene biosynthetic process 0.680353171851751 1.0894101862800898 0.2759730414316867 1.0 0.6259829884612537 4 Q9UJ14 1 +Regulation of translational termination 0.6789798422228295 1.084250231137337 0.2782538654364745 1.0 0.6284778364887208 4 P15170,P63241 2 +Inflammatory response to antigenic stimulus 0.5325997321685727 1.08299013839894 0.2788128002790109 1.0 0.6288808545182941 11 P28070,P26583,P09429,Q04721 4 +Regulation of cysteine type endopeptidase activity 0.4178328979010854 1.0823011747108424 0.2791187241884998 1.0 0.6288808545182941 52 Q13177,Q9NR28,P09429,P78318,P61201,Q96K76,Q15375,Q92688,Q15392,Q9Y6N7,Q99538,Q9BXI6,O95831,P23396 14 +Mitochondrion distribution 0.677868642839363 1.0800771525759616 0.2801078250269586 1.0 0.629500947395741 4 O00429,Q9BUK6 2 +Regulation of mitotic centrosome separation 0.7987658192229927 1.0785335580910886 0.280795714169868 1.0 0.6307540227550641 3 P43487 1 +Synaptic vesicle membrane organization 0.6300706213152473 1.0771168246156035 0.2814280775646369 1.0 0.6313547966436469 5 O14656,O43760 2 +Positive regulation of b cell mediated immunity 0.5598700273561968 1.0758079872406192 0.2820131393894691 1.0 0.6318400650217739 9 P02786 1 +T cell extravasation 0.7975015465944278 1.0740773571549789 0.2827880119866002 1.0 0.6327323474654243 3 Q9Y624 1 +Positive regulation of i kappab kinase nf kappab signaling 0.4350863168644636 1.0738347000481172 0.282896774555132 1.0 0.6327323474654243 39 Q7Z7H5,O75179,O43657,Q9Y6K9,Q92734,P02786,P62942 7 +Response to progesterone 0.6759108639885247 1.0727291989486354 0.2833926355218457 1.0 0.6327323474654243 4 Q05086,Q969T9 2 +Actin filament polymerization 0.4190744290307065 1.0726202294741571 0.2834415444968972 1.0 0.6327323474654243 44 P35080,O95429,Q14247,Q12959,Q9NSV4,P63000,Q9UJU6,O94813,Q9UQB8,P07737,P47756,P62993,Q6IBS0,O15143 14 +Microtubule polymerization 0.460719326109714 1.0723610150323972 0.2835579111792168 1.0 0.6327323474654243 27 Q15691,P04350,Q02790,Q96P70,P63000,Q08379,Q13526,P36405,Q16512,P23258,Q96CW5,Q14203,P16949,P23396 14 +Cellular response to insulin stimulus 0.4170483051853826 1.071931795541217 0.2837506677523767 1.0 0.6327323474654243 51 Q06481,Q9H1E3,P62993,O00459,Q9UQB8,Q15043,Q9BSK2 7 +Regulation of synapse maturation 0.7893642305407038 1.0717012595142712 0.2838542349301409 1.0 0.6327323474654243 2 Q12834 1 +Alcohol catabolic process 0.5144441527791778 1.0699109583067443 0.2846593900566061 1.0 0.6343121503361636 13 Q8WTV0,Q9NX62 2 +Pyrimidine nucleoside triphosphate metabolic process 0.5216057504798971 1.0663298484972925 0.2862745611311337 1.0 0.636402184224602 12 Q9H773,Q9NRF8,Q9BZX2 3 +Oligopeptide transport 0.672792005435492 1.0610355553912685 0.2886737430775907 1.0 0.6402211335011436 4 Q9UPY5,P33527 2 +Tripeptide transport 0.672792005435492 1.0610355553912685 0.2886737430775907 1.0 0.6402211335011436 4 Q9UPY5,P33527 2 +Cell differentiation involved in metanephros development 0.6719816430365748 1.0579997454260612 0.2900555584645146 1.0 0.6417710943759088 4 P11047 1 +Metanephric nephron development 0.6719816430365748 1.0579997454260612 0.2900555584645146 1.0 0.6417710943759088 4 P11047 1 +Cellular component disassembly involved in execution phase of apoptosis 0.5557327074163155 1.057535691569784 0.290267174396551 1.0 0.642023360181746 9 O00115 1 +Potassium ion import across plasma membrane 0.5995937247462354 1.0571830028578015 0.29042807552793 1.0 0.6421633212849491 6 Q9BXP2 1 +Cell migration 0.4627344280105779 1.0567170785016902 0.29064072821318 1.0 0.6424175773475463 230 Q06481,O94898,O00560,P26583,Q92859,P84095,P67870,Q14118,P05067,Q9Y6N7,Q99538,P78310,Q9Y2I1,P05556,Q8TEY7,Q13685,P78536,P42785,Q07954,Q14517,P49768,Q13308,P19022,P33527,P10586,O94813,Q13641,Q9Y4G8,P11047,P07686,Q8WTV0,Q08722,P43121,P06756,P04062,P09429,P07942,Q9Y624,P35613,P29317,O14786 41 +Dendritic spine development 0.4617945448861704 1.0555976262679785 0.2911520858616234 1.0 0.6430595733693827 26 Q14444,Q9UJU6,P43034,Q06787,O60678,P49768,Q9UQB8 7 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4530343622409773 1.0554393029156923 0.2912244556198526 1.0 0.6430595733693827 29 P62829,Q96KB5,O15372,P62913,P60520,O00560,P54578,Q92530,Q9NZM5,P49768,P08238,P78559,Q04323 13 +Protein targeting 0.4033938993798576 1.0541638638122683 0.2918079012438463 1.0 0.643789642177434 122 Q14108,Q99523,Q99595,Q13438,O60830,Q9H173,P13473,P27105,Q8N3F8,P20645,O00170,Q10713,Q8N4H5,P55786,O95831 15 +Ribonucleoside metabolic process 0.5708376111440863 1.054024783717229 0.2918715704621237 1.0 0.643789642177434 8 Q9NRG1,P07741,P00491,P00492,O60725 5 +Purine ribonucleoside metabolic process 0.5708376111440863 1.054024783717229 0.2918715704621237 1.0 0.643789642177434 8 Q9NRG1,P07741,P00491,P00492,O60725 5 +Dendrite extension 0.5985828927608987 1.0531210315640709 0.2922855248821392 1.0 0.643789642177434 6 Q96PU5 1 +Protein retention in er lumen 0.6237953680474947 1.0525887211444556 0.2925295286745883 1.0 0.643789642177434 5 O43731 1 +Maintenance of protein localization in endoplasmic reticulum 0.6237953680474947 1.0525887211444556 0.2925295286745883 1.0 0.643789642177434 5 O43731 1 +Cdc42 protein signal transduction 0.7912406130930223 1.052049517377151 0.2927768317055559 1.0 0.643789642177434 3 O14786 1 +Exocrine system development 0.5982761525464563 1.051888663555658 0.2928506336571292 1.0 0.643789642177434 6 O14786,Q14118 2 +Positive regulation of protein kinase b signaling 0.4901211868338613 1.0512129706609656 0.2931607872897803 1.0 0.643789642177434 17 P05556,O95429,Q13641 3 +Cellular response to vascular endothelial growth factor stimulus 0.5860088335014236 1.0511072400252848 0.2932093392491117 1.0 0.643789642177434 7 O14786,Q9Y6N7 2 +Cell cycle g2 m phase transition 0.4158916821024905 1.0493084033915228 0.2940361996237506 1.0 0.6444568759032474 46 P08183,Q13309,Q9Y619,P48681,P05067,Q13564 6 +Adiponectin activated signaling pathway 0.7900683834776625 1.047932963425083 0.2946694937197507 1.0 0.6446078914827137 3 Q06481 1 +Post translational protein modification 0.517572970443135 1.0467402682107545 0.2952193860911931 1.0 0.6449528800092555 12 Q8TBC4,O75718,Q9H9C1,Q32P28,O60725 5 +Endoderm development 0.501453494322946 1.045789939522146 0.2956580270556763 1.0 0.6454195064401048 14 P07942,P06756 2 +Tumor necrosis factor superfamily cytokine production 0.477058088781517 1.044591186882291 0.2962119545627646 1.0 0.6460484871067194 20 P49768,P05067,P09429,Q08722 4 +Actin filament based movement 0.4500299648613931 1.0443602649745334 0.2963187402035852 1.0 0.6460671770166335 30 Q14126,Q02487,Q9UM22 3 +Regulation of microtubule polymerization or depolymerization 0.4563349609664928 1.0437310990251332 0.2966098172534281 1.0 0.6464875340931248 27 Q66K74,Q15691,P04350,Q02790,Q15555,P46821,P63000,P23396,Q14203,P36405,Q16512,P78559,P16949,P29372,Q99828 15 +Positive regulation of early endosome to late endosome transport 0.6210745731303001 1.0419718140607734 0.2974247469223123 1.0 0.6473501923786167 5 P15311,P26038,Q9UL25 3 +Positive regulation of cytoplasmic transport 0.6210745731303001 1.0419718140607734 0.2974247469223123 1.0 0.6473501923786167 5 P15311,P26038,Q9UL25 3 +Positive regulation of plasma membrane bounded cell projection assembly 0.4560415797271165 1.0418145572386035 0.297497663660772 1.0 0.6473501923786167 27 Q9P2S5,Q15555,P63000,O14786,Q06787,P07737,Q9Y6W5,Q6IBS0,Q16181,Q9UHD8,P11233,Q9H6U6 12 +Regulation of viral entry into host cell 0.5956442415026209 1.0413195615036406 0.2977272609424362 1.0 0.6474533279738346 6 Q12899,Q92692 2 +Pyrimidine nucleotide metabolic process 0.4878585006659149 1.0387998470859077 0.298897832503822 1.0 0.6483143857182875 17 Q9H773,Q9NRF8,P13051,Q9BZX2 4 +Protein stabilization 0.3936437681243055 1.0379678033366224 0.2992850448296373 1.0 0.6483143857182875 74 Q15185,Q9UNS2,Q13526,Q16543,P07737,O15027,Q2M2I8,Q8TEY7,Q6VMQ6,P13473,P08238,O95429,Q9UJA3,P11279,O75955,P07900,Q32P28,Q9NZM5,P35080,P62913,O75718,Q86Y82 22 +Purine deoxyribonucleotide catabolic process 0.7792632204396949 1.0329713811927248 0.3016172918033384 1.0 0.651572592933453 2 Q9Y3Z3 1 +Deoxyribonucleoside monophosphate catabolic process 0.7792632204396948 1.0329713811927237 0.301617291803339 1.0 0.651572592933453 2 O43598 1 +Supramolecular fiber organization 0.4418375076105516 1.030138489709139 0.3029449993316078 1.0 0.6537966553816653 187 Q15691,P23396,P01130,Q9NYL9,P15311,Q9UJU6,Q13526,Q16527,P84095,P47756,A0MZ66,P07737,P23258,P05067,P67936,P62993,P49006,P62942,P16949,Q99828,P05556,Q66K74,P04350,Q96P70,Q9H2G2,Q9UHV9,Q9Y5K6,Q14517,P13674,Q07812,P49768,P06753,Q96ED9,P08238,O15143,P60983,Q99471,O95429,Q05682,Q14247,Q12959,Q02790,Q9NSV4,P63000,O94813,Q08379,Q96JJ3,Q9Y6W5,Q6IBS0,Q13177,Q14651,P78559,P07197,P29372,P10644,Q03001,P35080,Q96CW5,Q9Y624,P43034,O75718,P36405,Q9H9C1,Q15154,Q08722,Q14203,Q9UQB8,Q92791,O14786 69 +Regulation of protein depolymerization 0.4478058363419701 1.0292344538318208 0.3033695157072174 1.0 0.6542406270205635 30 Q66K74,O15344,P46821,Q9NYL9,P35611,P52907,P47756,P48681,P58546,Q6IBS0,P78559,P29372,O75083,Q99828 14 +B cell activation 0.4263438048672602 1.0286110797298171 0.303662469367838 1.0 0.6542406270205635 40 O15347,P05556,P78536,P78318,Q9Y4B6,P02786,Q9NPF0,P13051 8 +Regulation of lipid storage 0.549062802996627 1.028109584893674 0.3038982824512914 1.0 0.6542406270205635 9 Q8WTV0,Q9H4M9,P06756 3 +Response to endogenous stimulus 0.4752665641891656 1.0277575052107992 0.3040639101487101 1.0 0.6542406270205635 293 Q06481,P01130,Q9H1E3,O00560,P26583,Q92859,P67870,Q14118,Q13526,P05067,O00400,Q99538,P62942,Q9H4M9,Q9BSK2,P05556,Q99523,P78536,P42785,Q07954,P22466,O75874,Q9NR50,P16278,P49768,Q15043,Q6YHK3,O95429,P33527,Q92542,O15118,O94813,Q13309,Q8N0X7,Q9Y4G8,Q92896,O00459,Q9Y376,Q15392,O95831,P09960,P11166,O75312,Q8N122,P04062,Q53EL6,P35613,O75844,Q9UQB8 49 +Dendritic spine morphogenesis 0.4901763770764456 1.0276172780251618 0.3041298934580909 1.0 0.6542406270205635 16 Q14444,Q9UJU6,P43034,Q05086,O60678,Q9UQB8 6 +Inflammatory cell apoptotic process 0.6173827453043335 1.02758452162538 0.304145308213573 1.0 0.6542406270205635 5 P42771,O75844 2 +Microvillus assembly 0.5798242265229483 1.0256905700544092 0.3050374606705506 1.0 0.6546726872050391 7 P15311,Q9Y4G8 2 +Negative regulation of lipid transport 0.7837179124429678 1.025676468733399 0.3050441096527354 1.0 0.6546726872050391 3 P06756 1 +Regulation of gtpase activity 0.3992922684751709 1.0248352413201711 0.305440934858612 1.0 0.6546726872050391 68 P05556,Q9H2M9,Q0IIM8,Q13526,Q86X10,Q9UIW2,P84095,Q9Y4G8,Q86VI3,Q9Y624,P46108,P29317,P43034,Q9BXI6,Q9H6U6,P16949,P05198 17 +Negative regulation of intracellular protein transport 0.5200625048956604 1.023773973153193 0.3059420463136115 1.0 0.6546726872050391 11 Q13438,Q9ULC3 2 +Actin polymerization or depolymerization 0.4113608149328822 1.0237425522801964 0.3059568909790993 1.0 0.6546726872050391 51 Q9NYL9,Q9UJU6,P47756,P62993,P07737,P58546,P23528,Q96F07,O15143,O95429,Q14247,Q12959,Q9NSV4,P63000,P35611,P52907,O94813,Q6IBS0,P35080,Q14019,Q9UQB8,O75083 22 +Positive regulation of isotype switching to iga isotypes 0.7762923351158675 1.0216300603672173 0.3069560246219864 1.0 0.6559963385196319 2 O96028 1 +Lipid translocation 0.615588219596167 1.0205993168434622 0.3074443132755204 1.0 0.6568264672706637 5 P08183,Q9NV96 2 +Regulation of b cell mediated immunity 0.5185638779300752 1.0167050509498416 0.3092937622124529 1.0 0.6586950001119874 11 P02786 1 +Regulation of meiotic cell cycle 0.6144646274982366 1.0162285576470516 0.3095205602532918 1.0 0.6586950001119874 5 Q12834 1 +Response to bacterium 0.4038852630248464 1.0158181027545268 0.3097160138476922 1.0 0.6588169306743255 62 P01889,P78536,P09429,Q53EL6,P26583,Q9UQB8,Q5KU26,Q9BTY2,P29317,P04439,Q8WTV0 11 +Nuclear body organization 0.780801289826718 1.0154809061034424 0.3098766437514024 1.0 0.6588169306743255 3 O75312 1 +Late endosome to golgi transport 0.7808002830332265 1.0154773896466158 0.3098783191709278 1.0 0.6588169306743255 3 Q9UMY4 1 +Regulation of establishment of planar polarity 0.6602235830633265 1.0140778625824742 0.3105456003278757 1.0 0.6594282645358038 4 Q13308,P63000 2 +Gmp salvage 0.7798422808565604 1.0121322889587518 0.311474805752689 1.0 0.6605033114897448 3 P07741 1 +Tumor necrosis factor mediated signaling pathway 0.4825462296804178 1.0096617759706452 0.3126573615951924 1.0 0.662157155368054 17 P78536,Q8TCT8 2 +Negative regulation of cell junction assembly 0.5601937580933156 1.0087392878572208 0.3130996845498239 1.0 0.6627663818354848 8 Q15375 1 +Positive regulation of tor signaling 0.5443095793555228 1.0071677627640792 0.313854161945301 1.0 0.6638368737222476 9 Q8N122,Q15382,Q9NWS0 3 +Positive regulation of stress fiber assembly 0.5013558823507864 1.0045242172738846 0.3151260043706689 1.0 0.6654570968700675 13 P35080,O95429,P63000,Q08722,O14786 5 +Glomerular epithelial cell development 0.7772388786771289 1.0030514980243954 0.3158360146280801 1.0 0.6663147223295417 3 P11047 1 +Response to mechanical stimulus 0.4531720152727302 1.0002351401252736 0.3171967271887359 1.0 0.6676864228632016 26 P19022,Q9Y624,Q96QD8,P11166 4 +Negative regulation of microtubule polymerization or depolymerization 0.499807770803874 0.9967995669021584 0.3188618085405652 1.0 0.6692035932176104 13 Q15691,Q02790,P04350,O15344,P46821,P16949,P29372,Q99828 8 +Response to xenobiotic stimulus 0.3887803392058549 0.9904569939413724 0.3219507997313597 1.0 0.6738123960015541 74 P33527,P07099,P22466,P08183,O15118,O00170,P02786 7 +Regulation of microtubule polymerization 0.4692673007081376 0.988145578195219 0.3230813566268966 1.0 0.6748901758944827 19 Q15691,Q02790,P04350,P63000,P36405,Q16512,Q14203,P16949,P23396 9 +Germinal center formation 0.7670825906120076 0.9866284704901918 0.3238248077706327 1.0 0.6755850255360679 2 P78536 1 +Erbb signaling pathway 0.454243760164113 0.9863564146367864 0.3239582451589256 1.0 0.6756491238603084 25 P49768,Q99538,P78536 3 +Regulation of cell adhesion mediated by integrin 0.5698522623292296 0.984818620877282 0.3247131723519199 1.0 0.677008953322006 7 P46108,P29317 2 +Response to virus 0.3684934179474187 0.983283417247046 0.3254679692844582 1.0 0.677009396312029 87 Q9Y3E7,P19525,P61916,Q9Y6K9,Q9BUI4,Q13283,P16949,Q12899,P04792,O75179,O95801,Q9NUQ8,Q07812,P35269,Q13309,Q06787,P63241,P13693,Q9Y3Z3,P26641,Q96J02,O43657,O75844 23 +Secretory granule organization 0.6059231489671978 0.9830784538570704 0.3255688276941442 1.0 0.677009396312029 5 Q92692 1 +T cell chemotaxis 0.6056966077733035 0.9822011658731412 0.3260007533414342 1.0 0.677009396312029 5 P78536 1 +Lymphocyte chemotaxis 0.6056966077733035 0.9822011658731412 0.3260007533414342 1.0 0.677009396312029 5 P78536 1 +Positive regulation of interleukin 6 production 0.553683606797332 0.981113518409837 0.3265367647412107 1.0 0.6775719371463376 8 P05067 1 +Locomotory exploration behavior 0.7706963601369774 0.9802954392688572 0.3269403053363446 1.0 0.6775719371463376 3 Q9HB07 1 +Negative regulation of cell population proliferation 0.3863249460646342 0.978104084557068 0.3280228478943667 1.0 0.6790515523700803 109 Q6YHK3,Q06481,P22466,Q13641,Q9Y4G8,P05067,Q32P28,Q15392,Q9Y6N7,P10644 10 +Negative regulation of organic acid transport 0.7647058823529445 0.9776363165530076 0.3282542289719008 1.0 0.6790515523700803 2 Q9Y3D6 1 +Leukocyte adhesion to vascular endothelial cell 0.6504031371137826 0.9775971049747556 0.3282736297562869 1.0 0.6790515523700803 4 P05556,Q9H4A6 2 +Positive regulation of amino acid transport 0.6040159528562123 0.9756960781089092 0.3292150963193119 1.0 0.6798453884640135 5 P05556 1 +Reactive nitrogen species metabolic process 0.4762814405587648 0.975316891079502 0.3294030944013717 1.0 0.679891294311962 17 O43169,P06280,Q08722 3 +Regulation of kidney development 0.7689581398839207 0.9742657613636518 0.3299246001850506 1.0 0.6801140770972307 3 O95747 1 +Kidney mesenchyme development 0.7689581398839207 0.9742657613636518 0.3299246001850506 1.0 0.6801140770972307 3 O95747 1 +Metanephric mesenchyme development 0.7689581398839207 0.9742657613636518 0.3299246001850506 1.0 0.6801140770972307 3 O95747 1 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.4839514868789701 0.9737618702441342 0.3301747893776752 1.0 0.6801606563979182 15 P49768,P05067,P09429 3 +Secondary metabolite biosynthetic process 0.6493213661744442 0.973591151122476 0.330259581726803 1.0 0.6801606563979182 4 Q9UPY5,Q9Y4G8 2 +Negative regulation of potassium ion transport 0.6485512000509858 0.9707407191289724 0.3316774093898895 1.0 0.6815065243317152 4 Q96PU5,Q9Y376 2 +Negative regulation of potassium ion transmembrane transport 0.6485512000509858 0.9707407191289724 0.3316774093898895 1.0 0.6815065243317152 4 Q96PU5,Q9Y376 2 +Regulation of response to interferon gamma 0.7679049034175343 0.9706156255318038 0.3317397219383022 1.0 0.6815065243317152 3 Q15648,P08238 2 +T cell mediated immune response to tumor cell 0.7677013499915785 0.9699104835276184 0.3320911140247935 1.0 0.6820154068233193 3 P04439 1 +Late endosome to vacuole transport 0.5221845612433111 0.9691703294788376 0.3324602122068292 1.0 0.6825603233135213 10 Q9BRG1,Q9UQN3,Q9Y3E7,Q9H444 4 +Positive regulation of amine transport 0.5772250737968556 0.9676423475909436 0.3332230201899586 1.0 0.6829337362331596 6 P05556 1 +Positive regulation of oligodendrocyte differentiation 0.5771518249160978 0.967350513597338 0.3333688396236964 1.0 0.6829337362331596 6 Q15382,Q14118 2 +Ceramide biosynthetic process 0.5214613055516922 0.965885778373626 0.3341013394412822 1.0 0.6832948298626224 10 Q13510 1 +Cell cycle g1 s phase transition 0.3965989350416045 0.9646519060085252 0.3347191917470358 1.0 0.6835048712548262 64 P05556,O75312,Q8N122,P78536,Q06481,O75179,Q13309,Q86VI3,Q8N6R0,P49321 10 +Nucleoside monophosphate catabolic process 0.6005608828753176 0.9623417995313792 0.3358779386396726 1.0 0.6850704517006814 5 Q9NRG1,P00492,O43598 3 +Rna polyadenylation 0.4334041741324459 0.962061919951221 0.336018501090159 1.0 0.6850704517006814 33 Q5KU26 1 +Odontoblast differentiation 0.7605466428995884 0.9619423434462702 0.3360785669108184 1.0 0.6850704517006814 2 P07437 1 +Formation of translation preinitiation complex 0.5339746483148339 0.9617357931206282 0.3361823378062936 1.0 0.6850704517006814 9 Q15056,P23588,P55010,O43583 4 +Oligodendrocyte differentiation 0.4606675538630927 0.9610592408863884 0.33652238204064 1.0 0.6855510155042831 21 Q92542,O14744,Q9NR50,Q96P11,Q14118,Q15382,Q13144,P18074 8 +Response to food 0.5999506313369463 0.9599858088160076 0.3370623572446174 1.0 0.6864384476641155 5 P80303 1 +Sulfur compound transport 0.4846358094540359 0.9593468150090982 0.3373840586147851 1.0 0.6868809463225183 14 P33527,Q70HW3,Q8TDW0,Q9H0H5,O00400 5 +Retrograde axonal transport 0.5062205752863317 0.9585903127499648 0.337765174622779 1.0 0.6874245730098965 11 P78559,P43034 2 +Multicellular organism reproduction 0.4002844696678485 0.9579921164207033 0.3380667339076872 1.0 0.687632336315636 130 Q96SB4,Q9BQE5,P54619,Q9BXW9,Q99598,P26583,Q9GZP4,P05067,P11717,P78310,Q99828,P05556,Q8NB78,P04920,Q9H0H5,P49459,Q6IBW4,Q9H2V7,Q9UJA3,Q9Y2W6,O94813,P07686,P41208,Q15648,O75718,P43034,Q92692,Q8NB90,P35613,O60684,Q9H9C1,Q08J23 32 +L glutamate import across plasma membrane 0.5988589821527653 0.955773373939142 0.3391867431324638 1.0 0.6894840532525793 5 P05556,Q9UPY5,P49768 3 +Cerebral cortex neuron differentiation 0.6440802378714952 0.9542205258660786 0.3399720268229749 1.0 0.6902271581609657 4 P49768,P43034 2 +Negative regulation of phosphorylation 0.3798072124425637 0.9538448882657184 0.3401621637143253 1.0 0.6904000965482356 78 Q6YHK3,O94992,O60271,P04792,P04062,Q07954,Q53EL6,Q96KB5,O94813,O00410,O95373,Q86XL3,Q13177,P49768,Q96B36,P10644,Q99828 17 +Sulfur compound biosynthetic process 0.4043801214401662 0.9529621131140248 0.3406092671884979 1.0 0.6909750790608036 45 Q9UMR5,Q9UJ14,P50897 3 +Positive regulation of protein localization to early endosome 0.6435790725326916 0.9523716780709616 0.3409085177334034 1.0 0.6909750790608036 4 O75116,P26038,P15311 3 +Regulation of protein localization to endosome 0.6435790725326916 0.9523716780709616 0.3409085177334034 1.0 0.6909750790608036 4 O75116,P26038,P15311 3 +Cellular metabolic compound salvage 0.5048770829967757 0.9522785552868618 0.3409557305769639 1.0 0.6909750790608036 11 Q9NRG1,P07741,P00491,P00492,Q9BZX2 5 +Histone h2a phosphorylation 0.6433607876719885 0.951566594527484 0.3413168299340046 1.0 0.6910537481580082 4 O75844 1 +Positive regulation of protein serine threonine kinase activity 0.4348150895772615 0.9499561910218302 0.3421345132154973 1.0 0.6912914875534346 31 Q8N122,P23396,P78536,Q02750,Q9NWS0,Q9Y4G8,Q9Y376,Q9Y6N7,P49768,P08238,Q96A49,Q99828 12 +Regulation of cyclin dependent protein kinase activity 0.4712848900378278 0.9479470165838438 0.3431564278575227 1.0 0.6917591930094149 17 O94992,P32780,P78536,Q9P287,O00410,O75832,O95373,P08238 8 +Cell death in response to oxidative stress 0.4478484425492598 0.9459729312435218 0.3441623927840131 1.0 0.6917591930094149 25 Q9NR28,P04792,P04062,Q15118,Q99720 5 +Negative regulation of canonical wnt signaling pathway 0.4708157784865521 0.9453786405816113 0.3444656028429906 1.0 0.6917591930094149 17 Q13641 1 +Regulation of membrane lipid distribution 0.5601225694192693 0.9450973258271252 0.344609190455603 1.0 0.6917591930094149 7 P08183,Q9NV96 2 +Positive regulation of axon extension 0.4892496007242426 0.9441956913965328 0.3450696565756619 1.0 0.6917591930094149 13 A0MZ66,Q9UJU6,P43034,O14786 4 +Regulation of protein serine threonine kinase activity 0.3979957495161141 0.943490220672713 0.3454302150531092 1.0 0.6917591930094149 59 P54619,Q9P287,O75832,P42771,Q9Y6N7,Q96A49,Q99828,P32780,P78536,O00410,O95373,P49768,P08238,O94992,Q02750,Q9Y4G8,Q9Y376,Q9NWS0,P10644,Q8N122,P04062,Q53EL6,P23396 23 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.403164945698097 0.9422450994003936 0.3460671688621441 1.0 0.6917591930094149 44 P04062,Q9BW61,Q12834,Q06787,P49768,P53634 6 +Ear morphogenesis 0.474051790570879 0.9411739299011262 0.3466157342899105 1.0 0.6917591930094149 16 P54802,O95747,P63173,Q14651,Q13308 5 +Regulation of dendritic spine morphogenesis 0.4880944158383227 0.9384500404410708 0.348013180080446 1.0 0.6937366243355373 13 Q14444,Q9UQB8,P43034 3 +Regulation of receptor localization to synapse 0.7584955912521851 0.9381258186628832 0.348179754855773 1.0 0.6937366243355373 3 Q14118 1 +Embryonic organ development 0.3979878589475443 0.9378898608477336 0.3483010142897804 1.0 0.6937366243355373 58 P42892,Q12959,Q14651,Q02750,P54802,P27635,P62993,O95747,P48681,Q04721,P63173,P29317,P49768,Q15648,Q13308 15 +Morphogenesis of an epithelial sheet 0.5431809166453078 0.9366905933903688 0.3489177362880649 1.0 0.6942470869034758 8 P78536,Q04721,Q14118 3 +Potassium ion transport 0.4491383818685402 0.93597640181749 0.3492853378616136 1.0 0.6947683557465058 24 P05556,Q9BXP2,Q96PU5,P22466 4 +Regulation of translational elongation 0.5685586738209056 0.9331895321445848 0.3507221184816878 1.0 0.69584962358306 6 Q9H2P9,Q9BQC3,P49588,P63241 4 +Fat soluble vitamin metabolic process 0.5569431107051918 0.9321565106097832 0.3512556469735801 1.0 0.696371201263475 7 Q99538 1 +Regulation of actomyosin structure organization 0.4454608322151086 0.9308977389423948 0.3519064642385461 1.0 0.6972343053897962 25 P35080,O95429,P63000,Q08722,Q9Y624,P07737,Q9Y6W5,Q13177,P16949,O14786 10 +Proteolysis 0.4564886264090547 0.9307278844666648 0.351994341795498 1.0 0.6972343053897962 418 P42892,Q9Y3E7,O14773,Q9UIQ6,Q06481,O94898,Q6GQQ9,P78318,P28074,O75503,O00560,Q9HB40,Q14118,Q9GZP4,P05067,Q9Y6N7,P02786,Q99538,Q9H9Q2,Q9BXI6,O75976,Q4J6C6,Q8TEY7,P78536,P42785,Q07954,O14967,Q13438,P60520,P10619,P49459,Q92530,Q92688,P60900,P49721,P53634,Q92820,Q8TCT8,Q9UHG3,Q6YHK3,Q9H3G5,Q92542,Q96ES7,Q9H8M7,P28070,Q13309,Q92896,P28072,Q10713,Q9UJ14,Q15392,Q96PU5,O95831,Q7Z2K6,P04062,Q9UMY4,P09429,P04080,Q15375,O75844,P55786,O43847,P23396 63 +Positive regulation of vascular endothelial cell proliferation 0.6376360000177361 0.9304947451015136 0.3521149836583921 1.0 0.6972343053897962 4 P09429 1 +Vascular endothelial cell proliferation 0.6376360000177361 0.9304947451015136 0.3521149836583921 1.0 0.6972343053897962 4 P09429 1 +Protein localization to microtubule end 0.7513368983957258 0.9273937795205808 0.3537221191746305 1.0 0.6998992680467566 2 Q15691 1 +Mammary gland duct morphogenesis 0.6365693603580773 0.926577959513956 0.3541457028151331 1.0 0.6998992680467566 4 P29317 1 +Homeostatic process 0.4684781026327023 0.9263119854899342 0.3542838689937204 1.0 0.6998992680467566 311 O14773,Q9UIQ6,Q06481,P01130,O75503,P61916,Q9H1E3,Q92859,Q5BJF2,P26583,Q9BXP2,P05067,Q8NE01,P50897,P02786,P62942,P78310,P16949,Q9H4M9,P05556,P42785,Q93050,P13473,P10253,Q15043,P34913,O15260,P19022,Q92542,O15118,P02792,P11047,Q15904,P51790,O00115,P07686,O00459,P38571,Q7L0J3,Q96PU5,Q8WTV0,Q9NUM4,P06756,P11166,P04062,P09429,Q9Y624,O43847 48 +Negative regulation of molecular function 0.4491159006776954 0.9256173884015144 0.3546448535916178 1.0 0.6999261466923677 225 Q06481,P78318,Q9H1E3,Q13526,Q12834,P06280,O00170,P61201,P05067,P48681,P62942,P16949,Q8TEY7,Q99523,P04792,Q07954,P60866,Q96K76,Q92530,P49768,Q96B36,P35269,Q15043,P60983,Q6YHK3,O94992,O95429,Q04323,P10586,O94813,Q9BTT0,Q06787,O95747,Q9Y376,Q15392,Q96PU5,Q13177,P10644,P06756,P05198,Q8N122,O43924,Q9C0C9,P04062,Q53EL6,P04080,P62913,Q9Y624,Q86VP1,Q01105 50 +Positive regulation of neuron death 0.4628785906468505 0.9252509185810224 0.3548354028305178 1.0 0.7000921655126413 18 Q15375,O95831 2 +Epithelial tube morphogenesis 0.4007921290371739 0.9227499627536264 0.3561375221617429 1.0 0.7010542078070247 44 O94813,P67870,Q14118,O95747,Q15375,Q04721,P29317,P49768,Q13308,P11233,O14786 11 +Tetrapyrrole catabolic process 0.5901389400021491 0.9222256671980624 0.3564108774370567 1.0 0.7011016514243177 5 P33527 1 +Regulation of amino acid transmembrane transport 0.6345282896208794 0.9190914438394088 0.3580477442063532 1.0 0.7012517462831038 4 P05556 1 +Regulation of l glutamate import across plasma membrane 0.6345282896208794 0.9190914438394088 0.3580477442063532 1.0 0.7012517462831038 4 P05556 1 +Leukotriene metabolic process 0.5649065295836675 0.9187194534465528 0.3582423319261607 1.0 0.7012517462831038 6 P33527,Q9UJ14 2 +Establishment of planar polarity involved in neural tube closure 0.7489601901366663 0.9185257638599876 0.3583436770446524 1.0 0.7012517462831038 2 Q13308 1 +Establishment of endothelial barrier 0.4615144509697748 0.9176169677757317 0.3588194314970578 1.0 0.7012517462831038 18 Q9Y624 1 +Enucleate erythrocyte differentiation 0.7486631016042822 0.9174186943086224 0.3589232803377284 1.0 0.7012517462831038 2 Q15648 1 +Glycerolipid biosynthetic process 0.3981528620257637 0.9143245395520084 0.3605463398288706 1.0 0.7020940862623773 52 P35790,P01130,Q8NCC3,Q10713,Q8WTV0,Q9NX62 6 +Negative regulation of epidermal growth factor activated receptor activity 0.5874596191204478 0.9119561159702296 0.3617918192809921 1.0 0.7034522373575072 5 P49768,Q9BRG1,Q9UNH7 3 +Cellular response to endogenous stimulus 0.4527893624006087 0.9115752196727656 0.3619923720667621 1.0 0.7034522373575072 239 Q06481,Q9H1E3,O00560,Q13526,Q92859,P67870,P05067,O00400,Q99538,P62942,Q9H4M9,Q9BSK2,P05556,Q99523,P78536,P42785,Q07954,P49768,Q15043,Q6YHK3,O95429,P33527,Q92542,O15118,O94813,Q13309,Q8N0X7,Q9Y4G8,Q92896,O00459,O95831,O75312,Q8N122,Q53EL6,O75844,Q9UQB8 36 +Multi organism reproductive process 0.4167120435122771 0.9079382526282268 0.3639108459119842 1.0 0.7059577494164155 162 Q96SB4,Q9BQE5,Q9UIQ6,Q9BXW9,Q99598,P26583,Q9GZP4,P05067,P11717,P78310,P05556,Q8NB78,O14967,Q9H0H5,P49459,Q6IBW4,Q9H2V7,Q9UJA3,Q9Y2W6,Q08431,P07686,P41208,Q15648,P11166,O75718,P43034,Q96QD8,Q8NB90,Q92692,Q15056,P35613,O60684,Q9H9C1,Q7Z739,Q08J23 35 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.5860583229784109 0.9065927153803044 0.3646222153924272 1.0 0.7061970146914635 5 Q6VMQ6,P09429 2 +B cell mediated immunity 0.463700831865152 0.9064587153373216 0.3646931071612802 1.0 0.7061970146914635 17 P02786,P13051,Q92692 3 +Establishment of planar polarity of embryonic epithelium 0.7491827637444287 0.9061958301019856 0.3648322097422589 1.0 0.7062584684180633 3 Q13308,P43034 2 +Regulation of tau protein kinase activity 0.7488855869242208 0.9051808858167228 0.3653695663442273 1.0 0.7070432733832708 3 P08238,P07900 2 +Gland morphogenesis 0.4672541669070011 0.9048203305859756 0.3655605792025609 1.0 0.7070432733832708 16 Q9UIW2,Q14118,P29317,Q04721,Q07812,Q15648,O14786 7 +Blastoderm segmentation 0.6305180987267284 0.9044156419730052 0.3657750470239085 1.0 0.7070432733832708 4 Q9Y2W6,O14786 2 +Regulation of protein localization to cell surface 0.4877420830911405 0.9024019008279583 0.3668434117332833 1.0 0.7078604651073543 12 Q96PU5,P78559,O94898 3 +Mesoderm development 0.4628039693939874 0.9015579344252754 0.367291745263484 1.0 0.7078949706742765 17 P05556,Q96PZ0,O95747,P63173,P29317,P10644 6 +Vitamin metabolic process 0.4300416211449077 0.9006657606305852 0.3677660586759563 1.0 0.7078949706742765 29 Q99538,Q9NPF0,P04062,P33527 4 +Cytoskeleton dependent intracellular transport 0.3902907168892892 0.8995442197878813 0.3683628532230441 1.0 0.7078949706742765 63 Q9Y678,P11279,P78559,P43034,P07437,Q14203,P05067,Q8TD16,Q96ED9,Q14168,Q13409 11 +Protein localization to membrane raft 0.7436125965537771 0.8986484624156184 0.368839936524624 1.0 0.7078949706742765 2 O75955 1 +Regulation of toll like receptor 3 signaling pathway 0.7436125965537771 0.8986484624156184 0.368839936524624 1.0 0.7078949706742765 2 O75955 1 +Vesicle mediated transport between endosomal compartments 0.4500344589232899 0.8982178231235488 0.369069433171814 1.0 0.7078949706742765 21 Q9Y3E7,Q9UNK0,Q9UMY4,Q02750,P15311,O60493,Q96ED9 7 +T cell differentiation in thymus 0.5193044444166374 0.8975574687204403 0.3694215222465429 1.0 0.7078949706742765 9 P78536,P04062 2 +Positive regulation of g protein coupled receptor signaling pathway 0.5835990002705072 0.8971927997699367 0.3696160466334193 1.0 0.7080181580531836 5 Q15043 1 +Cholesterol storage 0.7460743400510658 0.895592280657612 0.3704705599906939 1.0 0.7093263736581297 3 Q8WTV0 1 +Postsynapse to nucleus signaling pathway 0.7456166419019326 0.8940333475258608 0.3713040490846109 1.0 0.7097635064111193 3 P52292,P52294 2 +Regulation of protein maturation 0.4791033255457062 0.8938132479367333 0.3714218197638819 1.0 0.7097635064111193 13 Q92896 1 +Positive regulation of mitotic cell cycle 0.3967278134271136 0.8916063410989747 0.3726039701389396 1.0 0.710762859274362 47 Q8N122,P78536,O75179,P05067,Q99538 5 +Regulation of actin filament length 0.396937008647467 0.8910574493255907 0.3728983507893095 1.0 0.710762859274362 44 P35080,O95429,Q96F07,Q14247,Q12959,Q9NYL9,Q9UJU6,P52907,O94813,Q9UQB8,P47756,P62993,P07737,P58546,Q6IBS0,O15143,O75083 17 +Kidney morphogenesis 0.5319541250892248 0.889447607182759 0.3737625689590167 1.0 0.711867919744559 8 O95747,P80723,Q12959,O75844 4 +Negative regulation of immune response 0.4411181585342517 0.8862147647653257 0.3755018089019726 1.0 0.7138875430512069 24 P01889,P28070,P17931,P25786,P46108,Q9Y3Z3,Q7Z739,P04439 8 +Regulation of pigmentation 0.7394533571004203 0.8832636838342471 0.37709382045062 1.0 0.7158796972364152 2 Q07812 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.4492056011942211 0.8824573333304213 0.3775295430578054 1.0 0.7162331124747991 20 Q96KB5,P62913,P54578,O00560,Q9NZM5,P08238,P78559,Q04323 8 +V d j recombination 0.5556662904403491 0.882254261425346 0.3776393246535556 1.0 0.7162331124747991 6 P26583,P09429 2 +Tripeptide transmembrane transport 0.7420825498773705 0.8820171813537343 0.3777675161062146 1.0 0.7162331124747991 3 P33527 1 +Actin filament depolymerization 0.4489247311827825 0.8808258698488108 0.3784120753662656 1.0 0.7165024176787717 20 Q9BPX3,Q9NYL9,Q9UHB6,P47756,O15020,P58546,P23528,Q13813,Q13045,Q9Y281,P35241,Q9UEY8,P47755,P35611,P52907,Q6IBS0,Q12792,O75083,P60981 19 +Negative regulation of defense response to virus 0.5437993944095861 0.8789004441393614 0.3794552578446355 1.0 0.7176515616218584 7 O43657 1 +Torc1 signaling 0.5436461653479383 0.8782820949392381 0.37979065007401 1.0 0.7176515616218584 7 Q8N122,Q6PKG0 2 +Phospholipid catabolic process 0.4759415792407516 0.8781564067361389 0.3798588455605216 1.0 0.7176515616218584 13 P01130,Q8NHP8,Q8NCC3 3 +Regulation of exocytosis 0.3951919410887474 0.8777674354142341 0.3800699400175134 1.0 0.7176515616218584 46 Q9Y3E7,O95219,P11279,O00560,Q06787,Q4J6C6 6 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.4266111651290297 0.8775654261149028 0.3801795987594767 1.0 0.7176515616218584 29 Q9Y4X5,P04062,Q9BW61,Q12834,O75832,Q9NZM5,P49768,Q9UNE7 8 +Negative regulation of phosphorus metabolic process 0.3662497494974344 0.8756170112590017 0.3812382743414824 1.0 0.7183573098304988 96 O60271,Q96KB5,P17931,P62942,Q99828,P04792,Q07954,O00410,O95373,Q86XL3,P49768,Q96B36,Q6YHK3,O94992,O95429,O94813,Q13177,P10644,P04062,Q53EL6 20 +Establishment of golgi localization 0.622058793505305 0.8736113030775081 0.3823299685967707 1.0 0.7197958023553399 4 Q9Y678,P63104 2 +Positive regulation of dna binding transcription factor activity 0.4034955691758222 0.8723842712693652 0.3829987782077224 1.0 0.7204363634688012 41 Q12899,Q9Y6K9,P05067,P02786,P23396 5 +Dna replication checkpoint signaling 0.5763585844801223 0.8696202025079549 0.3845079935958737 1.0 0.7218242226238961 5 Q9Y619 1 +Purine deoxyribonucleotide metabolic process 0.6206843916620832 0.8686272241534021 0.3850510588513489 1.0 0.7218242226238961 4 P00491,Q9Y3Z3 2 +Protein deglycosylation 0.5124864389102913 0.8678881831129603 0.3854555485932807 1.0 0.7218242226238961 9 O60476,O00754 2 +Biological process involved in intraspecies interaction between organisms 0.5758914938892072 0.8678468874022078 0.3854781580951962 1.0 0.7218242226238961 5 Q8N122 1 +Cellular response to hydrogen peroxide 0.446267449252267 0.8653970342657521 0.3868209082324898 1.0 0.7232825282414207 20 Q99720,O95831 2 +Regulation of dna methylation 0.5114697307402738 0.8634738237084604 0.3878770054654823 1.0 0.7243416369291745 9 O75844 1 +Glycosyl compound metabolic process 0.4252659556987913 0.862391414033566 0.3884721636923627 1.0 0.7249276291541452 28 Q9BTY2,P04066,P06280 3 +Negative regulation of ubiquitin dependent protein catabolic process 0.4315893793979201 0.8616072447320585 0.3889036829597674 1.0 0.7250006941202016 26 P62829,Q96KB5,O15372,P62913,P54578,O00560,Q9NZM5,P49768,P08238,P78559,Q04323 11 +Regulation of dephosphorylation 0.416565501212487 0.8546087211605666 0.3927677979007802 1.0 0.7306636240360103 34 O95429,P04062,P78318,Q13526,P67870,Q86XL3,P08238,P62942 8 +Positive regulation of deoxyribonuclease activity 0.7314319667260913 0.853789868415825 0.393221429172415 1.0 0.731093996918074 2 P23396 1 +Response to vitamin a 0.7311348781937064 0.8527034203837974 0.3938237936362805 1.0 0.7313870453245209 2 P46821 1 +Carbohydrate homeostasis 0.3919635401384835 0.8518298503878251 0.3943085360717027 1.0 0.7316675741268435 47 Q9H1E3,Q15043,P42785,Q06481 4 +Response to lipid 0.4039508706357598 0.850626551796056 0.394976835150914 1.0 0.7320149658965976 150 P78536,P04062,P09429,O15118,P01130,Q53EL6,O94813,Q13309,Q15126,P26583,O75874,Q14118,P11717,P16278,P02786,O95831,Q8WTV0,P49321 18 +Regulation of protein k63 linked ubiquitination 0.547415593508626 0.8498904240332693 0.395386010007694 1.0 0.7320149658965976 6 P61088 1 +Negative regulation of ion transport 0.4492484997578057 0.8491057663229538 0.3958224420686815 1.0 0.7320498574996049 18 Q9UKS6,Q06787,O95747,Q9Y376,P46934,Q96PU5,O75915,P62942 8 +Glycosyl compound catabolic process 0.5222837353821961 0.8489995131105297 0.3958815632049792 1.0 0.7320498574996049 8 Q9BTY2,P04066,P06280 3 +Rescue of stalled ribosome 0.5361510896383408 0.8481149486112043 0.3963739572911078 1.0 0.7321005093624491 7 O60524,Q15650 2 +Organic hydroxy compound catabolic process 0.4594904255244453 0.8459312660900529 0.3975910892047007 1.0 0.7321005093624491 15 Q8WTV0,Q9NX62 2 +Mrna 3 end processing 0.4051846341964932 0.8458300695841368 0.3976475482675874 1.0 0.7321005093624491 39 Q5KU26 1 +Regulation of meiotic nuclear division 0.7312396511436634 0.8453944581229713 0.3978906376723823 1.0 0.7321005093624491 3 Q12834 1 +Production of sirna involved in rna interference 0.6140483288516412 0.844649428849377 0.3983066026670463 1.0 0.7321005093624491 4 Q15631,Q99598 2 +Divalent inorganic cation homeostasis 0.3856449186434681 0.8444360252071373 0.3984257985058086 1.0 0.7321005093624491 61 P09429,Q9HC07,P05067,Q8NE01,P07686,P49768,P62942,Q7L0J3,Q15043,P06756 10 +Ribosome associated ubiquitin dependent protein catabolic process 0.5455322240052839 0.8425313123504292 0.3994906203682116 1.0 0.7328908766075992 6 O60524,Q15650 2 +Interferon gamma mediated signaling pathway 0.5686780802761884 0.8405502831681774 0.4005999208733963 1.0 0.7334412277192768 5 P08238,Q15648 2 +Inclusion body assembly 0.5193452380952396 0.8367603879015941 0.4027272674585291 1.0 0.73607667833904 8 P62333,P62195,Q9UL15,P54652,P0DMV9,P25685,O95817 7 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.5439253859483224 0.836261576020405 0.4030077642723131 1.0 0.7363847426064655 6 P17812,Q9NRF8,Q9BZX2 3 +Regulation of heterotypic cell cell adhesion 0.7281863224234608 0.8351516794296114 0.4036323121402096 1.0 0.7365030095029955 3 O75955 1 +Positive regulation of protein tyrosine kinase activity 0.5669985810537819 0.8342198277718608 0.404157119950149 1.0 0.7371435972457722 5 P78536 1 +Dna replication synthesis of rna primer 0.6103268404917908 0.831268616167123 0.4058218997560905 1.0 0.738858692664147 4 Q14181,P49642 2 +Platelet aggregation 0.4595201599644537 0.8310531540802334 0.4059436022389715 1.0 0.7388757652263294 14 Q9UPY5,P04792,Q13418,O00299,Q9Y624 5 +Regulation of sodium ion transmembrane transport 0.4496978872795802 0.8301180196334398 0.4064720599260547 1.0 0.739428432022563 17 Q12959,Q9UHD1,P27105,O95747,Q04917,O43707,P46939,O14745,P54709,P46934,Q96PU5 11 +Regulation of synaptic transmission glutamatergic 0.5651306304198043 0.8271906503679142 0.4081290101367507 1.0 0.7415590337025724 5 P19022 1 +Pyridine containing compound catabolic process 0.7257057949479949 0.8268542540411872 0.4083196746839035 1.0 0.7415590337025724 3 P00491,Q6SZW1 2 +Cellular response to external stimulus 0.3862815033121178 0.8254739724774748 0.4091025534411692 1.0 0.7423659576651064 56 Q8TEY7,Q8N122,Q02487,P04062,Q9Y624,P13473,Q14118,Q96QD8,Q9H773,O95831,P11166 11 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.3872876307731286 0.8239335287907428 0.4099773280294307 1.0 0.7427240054468729 53 Q9Y4X5,Q96KB5,P04062,O15372,P62913,Q9BW61,P54578,O00560,Q12834,O75832,Q9NZM5,P49768,P08238,P78559,Q9UNE7,Q04323 16 +Cellular response to ether 0.7245057073286603 0.8228477511799405 0.4105945781106368 1.0 0.7431792868106095 3 Q6PKG0 1 +Regulation of smooth muscle cell differentiation 0.5639346290895045 0.8226965854852593 0.410680557548885 1.0 0.7431792868106095 5 Q53EL6 1 +Canonical wnt signaling pathway 0.4061727373209146 0.8197959960970909 0.4123324139578395 1.0 0.7453483426805904 37 Q99471,P19022,Q13418,Q13526,Q13641,O75787,Q96K76,Q13308,P49768,Q13283 10 +Gland development 0.3724348514399078 0.819055297963927 0.4127548645967487 1.0 0.745570415836072 73 P07741,Q9UIW2,Q14118,Q86VI3,P61201,P29317,P11717,Q04721,Q9Y6N7,P49768,O75844,P07602,O14786 13 +Barbed end actin filament capping 0.4760250329538516 0.8176863827354554 0.4135362879796527 1.0 0.746498820617496 11 Q9BPX3,P35611,P52907,P47756,P35241,P58546,Q6IBS0,Q12792 8 +Extracellular exosome assembly 0.7224368499257067 0.815953030842181 0.4145269998171184 1.0 0.7474271264793354 3 O00560,Q8WUM4 2 +Limbic system development 0.4320612603938451 0.8157499863050796 0.414643143393633 1.0 0.7474271264793354 23 P43034,P46108,P18887,Q13144,O14786 5 +Response to steroid hormone 0.3740996986348725 0.8147243086518182 0.4152301356498451 1.0 0.7476758761180986 71 P04062,O15118,Q13309,O94813,P26583,P16278,O95831 7 +Glandular epithelial cell development 0.5382842466894178 0.8143176607323059 0.4154629948957553 1.0 0.7476758761180986 6 P19022 1 +Lung morphogenesis 0.4877230197747476 0.8138929560722862 0.4157062763273709 1.0 0.7476758761180986 10 O00203,P28482,Q02750,O95487,Q14118 5 +Protein transmembrane import into intracellular organelle 0.4556872455709216 0.8116095835028934 0.4170156904564681 1.0 0.7480246662064499 14 O60830,Q99595 2 +Regulation of canonical wnt signaling pathway 0.406825847855687 0.8100468659102402 0.4179132406445984 1.0 0.7484435875197845 36 Q99471,P19022,Q13418,Q13526,Q13641,O75787,Q96K76,Q13308,P49768,Q13283 10 +Reelin mediated signaling pathway 0.7205412809859723 0.8096495538776395 0.4181416189599773 1.0 0.7484533459369644 3 P43034 1 +Somatic diversification of immune receptors 0.4233325406063598 0.8086741150351497 0.4187026210668567 1.0 0.7487786188787663 26 P09429,P26583,Q9Y3Z3,Q9Y4B6,P02786,P13051 6 +Transport of virus 0.5365776667625987 0.807700587789436 0.4192629651605015 1.0 0.7492989916320464 6 P42566,O60684,Q06787 3 +Negative regulation of epithelial cell proliferation 0.4452866982623578 0.8061646041144688 0.4201479449351404 1.0 0.7496135521749668 17 Q6YHK3 1 +Positive regulation of phosphorus metabolic process 0.3923901417394159 0.8045339703060093 0.4210886587165032 1.0 0.7496135521749668 139 P23396,P54619,O00560,Q13526,P67870,Q14118,P05067,Q9Y6N7,P02786,Q9H223,Q96A49,Q99828,P78536,Q86XL3,P49768,P08238,P51114,O95429,Q12959,Q02750,O75955,Q9Y4G8,P07900,Q86VI3,Q06787,Q9Y376,Q13177,Q9NWS0,Q8N122,P04062,Q15375,Q86Y37,P29317,Q969S3,O14786 35 +Negative regulation of actin filament depolymerization 0.4483890214797208 0.8044142821521338 0.4211577555551837 1.0 0.7496135521749668 16 Q9BPX3,Q13813,Q13045,P35611,Q9NYL9,Q9UHB6,P52907,P47756,O15020,P35241,Q9UEY8,P58546,Q6IBS0,Q12792,P47755 15 +Inner cell mass cell proliferation 0.5356516101512732 0.8041142395433771 0.421331001570667 1.0 0.7496135521749668 6 O75312,P61201,Q9BRT9 3 +Ubiquitin recycling 0.6022438876915037 0.8023802694284423 0.4223330227810074 1.0 0.7496135521749668 4 Q16763,P61086 2 +Positive regulation of production of molecular mediator of immune response 0.4319037546026616 0.802258793945271 0.4224032729553175 1.0 0.7496135521749668 22 P02786 1 +Intracellular distribution of mitochondria 0.7171717171717222 0.8020864742002797 0.4225029384886127 1.0 0.7496135521749668 2 O00429 1 +Cellular response to nitrogen starvation 0.7165775401069588 0.7999528086243812 0.4237381395686701 1.0 0.7500719849380554 2 P60520 1 +Cell cell junction organization 0.3852804003224097 0.796008204342519 0.426027266765105 1.0 0.7529305106880335 47 Q14126,P78310,Q9Y624,P29317 4 +Cellular process involved in reproduction in multicellular organism 0.3844643947780501 0.794754395439096 0.4267563837827435 1.0 0.7538140420308503 51 P05556,Q8NB78,Q9Y2W6,O94813,P26583,P43034,Q92692,Q9GZP4,Q08J23,Q6IBW4,P07686,P78310,Q96SB4,Q99828 14 +Apical junction assembly 0.4263060051630321 0.794528298424224 0.4268879414629178 1.0 0.7538439943471339 24 Q9Y624 1 +Regulation of gastrulation 0.5562966679537868 0.7941220495193704 0.4271243824005826 1.0 0.7540590948553495 5 Q14118 1 +Epithelium development 0.4184259133774284 0.7913790151459915 0.4287228518396047 1.0 0.7560694153889864 184 P42892,O14773,Q9P287,P67870,Q14118,Q9Y6N7,P07602,P78536,P22466,Q14517,P49768,Q13308,Q6YHK3,P19022,Q13510,O94813,Q9Y4G8,Q86VI3,P11047,P11233,P09960,O43598,Q9Y624,P43034,P07437,Q15375,O75844,P29317,Q08J23,O14786 30 +Chaperone mediated protein complex assembly 0.4701591636437665 0.7906145408050577 0.4291689589800849 1.0 0.7562479003940525 11 Q15185,Q9BT73,P07900,O95456,P08238,Q9UNE7 6 +Mammary gland development 0.427744993248575 0.7895359810819349 0.4297988085484867 1.0 0.7567409846788448 23 P07741,Q86VI3,P61201,P29317,Q9Y6N7,Q15648 6 +Humoral immune response 0.4640633405605187 0.7891574489317574 0.4300199882581894 1.0 0.7567409846788448 12 P04439,Q9UQ84 2 +Cytoplasm organization 0.7133095662507493 0.788248743834663 0.430551222449961 1.0 0.7570182641524171 2 Q9Y2W6 1 +Response to metal ion 0.3780111669525375 0.7873069158564053 0.4311022221822673 1.0 0.7570182641524171 63 P02786,Q99538,P05067,Q92542 4 +Regulation of synaptic vesicle exocytosis 0.4635371191651197 0.7866608220685685 0.4314804442528333 1.0 0.7572781116048926 12 Q4J6C6 1 +Regulation of multicellular organismal development 0.4215369072145535 0.7859820028631177 0.4318780308577528 1.0 0.7577737228547073 191 O15347,Q06481,Q9BXW9,P01130,P26583,Q14118,Q9Y6N7,P55209,P05556,P22466,P53634,Q6YHK3,O94813,Q13641,Q9Y4G8,Q92896,P01889,P09429,Q14444,Q9Y624,Q15375,O75844,P29317,Q9UQB8,O14786 25 +Response to amino acid starvation 0.4571038650587963 0.7854352055058694 0.4321984461391992 1.0 0.7579315858980679 13 P05198,Q6PKG0,Q96QD8 3 +Voluntary musculoskeletal movement 0.5971434021690991 0.7842816164159393 0.4328748839885483 1.0 0.7587132925330857 4 P78559 1 +Pyrimidine ribonucleotide biosynthetic process 0.5066100014687768 0.7840362019601608 0.4330188683203184 1.0 0.7587634831675691 8 P17812,Q9NRF8,Q9BZX2 3 +Late endosome to lysosome transport 0.5065326745611655 0.7837177846755126 0.4332057246094067 1.0 0.7588887500614321 8 Q9UQN3,Q9Y3E7,Q9H444,Q8WUX9 4 +Sensory perception of mechanical stimulus 0.4409526519063764 0.7826856841853054 0.4338117109631993 1.0 0.7591027364425244 17 Q14108,P07686 2 +Positive regulation of intrinsic apoptotic signaling pathway 0.4472233097974534 0.7823511369331362 0.4340082417796624 1.0 0.7591027364425244 15 Q9Y3D6,P23396,Q07812,P63241 4 +Female gamete generation 0.4285658469233402 0.7823396194929243 0.4340150086515741 1.0 0.7591027364425244 22 Q6IBW4,Q9Y2W6,P07686 3 +Odontogenesis of dentin containing tooth 0.4926542366261293 0.782330650163194 0.4340202784676701 1.0 0.7591027364425244 9 P04920,P35613,Q07812 3 +Eosinophil mediated immunity 0.7109328579916869 0.779770339920909 0.435526067511583 1.0 0.7591155655201891 2 Q12846 1 +Eosinophil activation 0.7109328579916869 0.779770339920909 0.435526067511583 1.0 0.7591155655201891 2 Q12846 1 +Regulation of carbohydrate metabolic process 0.4058453779519009 0.7780579704417622 0.4365348387962557 1.0 0.7597371760866731 34 Q14108,P05067,O75844 3 +Maternal process involved in female pregnancy 0.4673786763843728 0.7778258633270962 0.4366716785827305 1.0 0.7597371760866731 11 P49459,P35613,Q9BQE5 3 +In utero embryonic development 0.358854389238499 0.7771672932146799 0.4370600760300236 1.0 0.7597371760866731 98 P05556,O75312,Q9BRT9,Q02487,Q6GQQ9,Q8TCT9,P62993,Q14574,P49459,P67809,O43772,O43678,Q08J23,P61201,Q04721,Q15648,P49321 17 +Negative regulation of response to stimulus 0.4460007485318915 0.7764235693077335 0.4374989327318892 1.0 0.7597371760866731 256 P23396,Q9UMX5,Q06481,O94898,P01130,Q6GQQ9,P78318,Q13526,P26583,Q14118,Q9Y6N7,Q99538,P62942,P16949,P05556,P80303,P78536,Q07954,P49768,Q96B36,Q6YHK3,P19022,P28070,O94813,Q8N0X7,Q13641,Q92896,P67809,P13693,Q10713,O00459,Q9UJ14,P04439,Q08722,P06756,P01889,P04062,Q53EL6,O43657,P29317,O14786 41 +Non canonical wnt signaling pathway 0.5940821238776013 0.7734701428743501 0.4392441921119239 1.0 0.762121162470507 4 Q13308 1 +Extracellular vesicle biogenesis 0.490399176770817 0.7726850158090168 0.4397088166974383 1.0 0.7625638271119825 9 Q9Y3E7,O00560,Q8WUM4,O14964,Q92905 5 +Positive regulation of blood vessel endothelial cell migration 0.460453350225391 0.7720509740139312 0.4400842374320195 1.0 0.7630137358534065 12 P04792,O14786,P78536,P09429 4 +Regulation of dopamine receptor signaling pathway 0.7085561497326258 0.7713209120480709 0.4405167400832286 1.0 0.7633612002812112 2 O14744 1 +Positive regulation of dopamine receptor signaling pathway 0.7085561497326258 0.7713209120480709 0.4405167400832286 1.0 0.7633612002812112 2 O14744 1 +Regulation of activin receptor signaling pathway 0.708284698036006 0.7692242117849486 0.441760219546303 1.0 0.7645004298899317 3 P67870 1 +Activin receptor signaling pathway 0.708284698036006 0.7692242117849486 0.441760219546303 1.0 0.7645004298899317 3 P67870 1 +Establishment of cell polarity 0.3819699474746682 0.767896309687688 0.4425487900248446 1.0 0.7650983951763229 46 P05556,P35579,Q9H4A6,Q9UNZ2,P46821,P15311,P43034,P07900,Q14517,P46108,A0MZ66,P42858,Q96L92,P08238,Q14203,Q13308,Q9H6U6 17 +Hormone mediated signaling pathway 0.3817602502342692 0.7660177025284938 0.4436657689937184 1.0 0.766194126658094 45 Q06481 1 +Metal ion transport 0.36905546116476 0.7657358655823774 0.4438334819157414 1.0 0.7662825837379914 112 P05556,P49768,P22466,Q96PU5,P27105,P02792,Q96QD8,Q9HC07,Q06787,Q9BXP2,P13693,O75844,P02786,Q9H2J7,P62942,Q15043,P08195,P06756 18 +Microtubule depolymerization 0.4439500693281916 0.7654697317236868 0.443991883619258 1.0 0.7663549227099132 15 Q66K74,O15344,P46821,P78559,P16949,P29372,Q99828 7 +Ruffle assembly 0.4529333141609486 0.765065924645845 0.4442322894493327 1.0 0.7665174624067025 13 O95429,P63000,Q9UJU6,P84095,P07737 5 +Regulation of epithelial to mesenchymal transition 0.5019579480291554 0.764920129232791 0.4443191067431979 1.0 0.7665174624067025 8 O00560 1 +Phosphatidylinositol phosphate biosynthetic process 0.4761853640311938 0.7626736086054267 0.4456580736650033 1.0 0.767529766226066 10 Q9NX62 1 +Regulation of cytoplasmic translational elongation 0.7060921248142654 0.7620561245728826 0.4460265077256571 1.0 0.767529766226066 3 Q9H2P9,P49588 2 +Peptidyl histidine modification 0.7060921248142653 0.7620561245728815 0.4460265077256578 1.0 0.767529766226066 3 Q9H2P9,Q86TU7 2 +Peptidyl diphthamide biosynthetic process from peptidyl histidine 0.705882352941182 0.7618506628418726 0.4461491389839149 1.0 0.767529766226066 2 Q9H2P9 1 +Respiratory burst 0.5471964368820678 0.760381307892012 0.4470266930890985 1.0 0.767529766226066 5 P11274,P63000 2 +Negative regulation of ubiquitin protein transferase activity 0.4452492162957835 0.7589098194140569 0.4479065045675732 1.0 0.7682735298684477 14 P49768,Q12834,P62913 3 +Postsynaptic signal transduction 0.5237423910589604 0.7582826456205635 0.4482817942458736 1.0 0.7687167994132839 6 Q04206,P52292,P52294 3 +Negative regulation of small molecule metabolic process 0.4326778945135828 0.7571055182650044 0.4489866483005942 1.0 0.769323827174084 18 Q06481 1 +Insulin receptor signaling pathway 0.4220000366598851 0.7547211775973126 0.4504162969116705 1.0 0.7711708487987946 23 Q9H1E3,O00459,Q15043,Q9UQB8 4 +Sarcomere organization 0.4993721248810412 0.7543311206840873 0.4506504198721734 1.0 0.7712774103048778 8 P05556 1 +Protein depolymerization 0.385766406852104 0.753280089813002 0.4512816206019689 1.0 0.7713842827432356 42 Q66K74,O15344,P46821,Q9NYL9,P35611,P52907,O14976,P47756,P48681,P58546,P23528,Q6IBS0,P78559,P16949,P29372,O75083,Q99828 17 +Protein localization to postsynapse 0.5221337990693946 0.7521358496767907 0.4519693669151121 1.0 0.7722219469006772 6 Q14118 1 +Alpha beta t cell activation 0.450234107731893 0.7519192336955499 0.4520996307703155 1.0 0.7722439291631098 13 P04439,Q96J02,P09429 3 +Positive regulation of megakaryocyte differentiation 0.7027992727354186 0.7513290065539342 0.4524546765296366 1.0 0.7724938812000453 3 P26583 1 +Lamellipodium morphogenesis 0.5216731744858949 0.7503777268868004 0.4530272415707832 1.0 0.7728249987169636 6 O60749,Q13596 2 +Oocyte maturation 0.5870477591223723 0.7487801502727932 0.4539897255797593 1.0 0.773463976913664 4 P30153,Q15645 2 +Sperm egg recognition 0.4607270546491322 0.747356959259008 0.4548481186780773 1.0 0.7739598221785631 11 O14967,P50991,Q14157,P04075,P17987,Q99832 6 +Binding of sperm to zona pellucida 0.4607270546491322 0.747356959259008 0.4548481186780773 1.0 0.7739598221785631 11 O14967,P50991,Q14157,P04075,P17987,Q99832 6 +Regulation of inclusion body assembly 0.5208209399167242 0.7471273071847205 0.4549867182068263 1.0 0.7739598221785631 6 P62333,P62195,Q9UL15,P54652,P0DMV9 5 +Protein targeting to mitochondrion 0.3793140595364258 0.7461807537043523 0.4555582327798957 1.0 0.7741312465063689 47 Q99595,O60830,O00170,Q10713,Q8N4H5,P55786 6 +Positive regulation of macroautophagy 0.4205445385403978 0.7459165764986277 0.4557178110386657 1.0 0.7742024176168241 23 Q9H2M9,O95219,Q6UWE0,Q9Y6K9,Q6PKG0,Q13137 6 +Regulation of ruffle assembly 0.4970696526087952 0.7449254430458365 0.4563167930570664 1.0 0.7746740592774589 8 P07737,P84095 2 +Negative regulation of ion transmembrane transporter activity 0.4544790593908435 0.7438547429365179 0.456964357517913 1.0 0.7748876524027005 12 Q06787,O95747,Q9Y376,P46934,Q96PU5,P62942 6 +P38mapk cascade 0.7004457235074759 0.74369046094303 0.4570637617042523 1.0 0.7748876524027005 3 Q12959 1 +Regulation of p38mapk cascade 0.7004457235074759 0.74369046094303 0.4570637617042523 1.0 0.7748876524027005 3 Q12959 1 +Regulation of dna catabolic process 0.5854862419760637 0.7433294403703975 0.4572822516647661 1.0 0.7748876524027005 4 O95831 1 +Regulation of apoptotic dna fragmentation 0.5854862419760637 0.7433294403703975 0.4572822516647661 1.0 0.7748876524027005 4 O95831 1 +Actin filament organization 0.3676340545147761 0.7418557156853177 0.45817475925027 1.0 0.7753363250015834 113 P15311,Q9UJU6,P84095,P47756,A0MZ66,P07737,P67936,P62993,P49006,P16949,P05556,Q9Y5K6,Q14517,P06753,O15143,P60983,O95429,Q05682,Q14247,Q12959,Q9NSV4,P63000,O94813,Q96JJ3,Q9Y6W5,Q6IBS0,Q13177,Q14651,Q9Y624,Q08722,Q9UQB8,O14786 32 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4392625308110572 0.7413657652870862 0.4584716961197497 1.0 0.7753363250015834 15 P02786,P13051 2 +Somatic diversification of immunoglobulins involved in immune response 0.4392625308110572 0.7413657652870862 0.4584716961197497 1.0 0.7753363250015834 15 P02786,P13051 2 +Maintenance of apical basal cell polarity 0.699257057949481 0.7398418274559646 0.4593959756559569 1.0 0.7758425488741696 3 Q8WUM4,O75083 2 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.6992570579494808 0.7398418274559632 0.4593959756559578 1.0 0.7758425488741696 3 Q10713,Q9NZM5 2 +Extracellular transport 0.6990493166963813 0.7378246336668116 0.4606210219463282 1.0 0.7771957249663318 2 Q99816 1 +Regulation of smooth muscle contraction 0.6986084214521839 0.7377443297650358 0.4606698284651456 1.0 0.7771957249663318 3 Q14247 1 +Regulation of cell migration involved in sprouting angiogenesis 0.5408758540746801 0.7371589399127975 0.4610256997917301 1.0 0.7773973476621382 5 O14786 1 +Positive regulation of cell migration involved in sprouting angiogenesis 0.5408758540746801 0.7371589399127975 0.4610256997917301 1.0 0.7773973476621382 5 O14786 1 +Regulation of defense response to virus 0.4355479532449985 0.7366680725027475 0.4613242272558338 1.0 0.7774685756096693 16 O43657 1 +Ubiquitin dependent endocytosis 0.6980405165420809 0.7359094356909236 0.46178581456688 1.0 0.7774685756096693 3 Q6UWE0 1 +Regulation of actin filament organization 0.3685956089976718 0.7355225523115281 0.4620213103329833 1.0 0.7774685756096693 68 Q9NYL9,Q9UJU6,P47756,P62993,P07737,P16949,O15143,P60983,O95429,Q14247,Q12959,P63000,O94813,Q9Y6W5,Q6IBS0,Q13177,P35080,Q9Y624,Q08722,Q9UQB8,O14786 21 +Negative regulation of fibroblast apoptotic process 0.6978779239469824 0.7353843669369914 0.4621054399634245 1.0 0.7774685756096693 3 Q9BZZ5 1 +Immunological synapse formation 0.6977711738484408 0.7350396978085227 0.4623153177070007 1.0 0.7774685756096693 3 P17931,Q12959 2 +Positive regulation of protein polymerization 0.4060828490216052 0.7349964924851079 0.4623416302714831 1.0 0.7774685756096693 28 P35080,O95429,Q15691,Q14247,Q12959,P63000,P07900,P07737,Q16512,P62993,P36405,Q14203,Q9UQB8,P23396 14 +Thyroid gland development 0.6974739970282328 0.7340804586888845 0.4628997025607408 1.0 0.7780090681321907 3 Q02750,P28482 2 +Regulation of protein dephosphorylation 0.4058792903528769 0.7336491636089431 0.4631625890552842 1.0 0.7780090681321907 28 P62258,P04062,P17931,Q13526,P67870,Q86XL3,P42858,P08238,P62942,Q14738,Q12972 11 +Response to osmotic stress 0.4232027198767378 0.7321659213775212 0.4640673018501497 1.0 0.7783204758219653 20 P08183,Q8TDW0,P35237,O95747,Q9Y376,Q07812,P08238,P11166 8 +Regulation of xenophagy 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.7783204758219653 2 Q6UWE0 1 +Regulation of macrophage proliferation 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.7783204758219653 2 P28482 1 +Positive regulation of macrophage chemotaxis 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.7783204758219653 2 P28482 1 +Positive regulation of macrophage migration 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.7783204758219653 2 P28482 1 +Negative regulation of transporter activity 0.4458695977957611 0.7307266457505274 0.4649461367067165 1.0 0.7787012353144894 13 Q96PU5,P62942,Q9Y376,Q06787 4 +Post embryonic development 0.4278470321383787 0.7304525880237042 0.4651135836957478 1.0 0.7787012353144894 18 P11717,Q9NX62 2 +Regulation of cardiac muscle contraction 0.4394882373040041 0.7300048269666691 0.4653872341003504 1.0 0.7788128449940136 14 Q02487 1 +Regulation of ubiquitin protein ligase activity 0.4391750001415947 0.7284373245064051 0.466345922167235 1.0 0.7797721087992049 14 Q16763,P62829,O00429,P62913,P60866,Q12834,Q96GX5,P46777 8 +Positive regulation of mast cell activation 0.5809837863537681 0.7276767446944091 0.4668114892363852 1.0 0.7798421965905946 4 O95219 1 +Diapedesis 0.6960784313725548 0.7274600119097622 0.4669442031732873 1.0 0.7798421965905946 2 P46108 1 +Negative regulation of viral entry into host cell 0.6947994056463604 0.7254653194943245 0.468166613304622 1.0 0.7807757139681247 3 O60493,Q12899 2 +Negative regulation of viral life cycle 0.6947994056463604 0.7254653194943245 0.468166613304622 1.0 0.7807757139681247 3 O60493,Q12899 2 +Negative regulation of nf kappab transcription factor activity 0.4361334705208655 0.7253264588817186 0.4682517773797889 1.0 0.7807757139681247 15 Q86VP1,Q96J02,O75832 3 +Myofibroblast differentiation 0.6940076949664086 0.7229214174751993 0.4697281644198334 1.0 0.7819699306902296 3 Q53EL6 1 +Imp biosynthetic process 0.4914550968336283 0.7220851369742844 0.4702421356157666 1.0 0.7825023189104643 8 P07741 1 +Negative regulation of blood vessel endothelial cell migration 0.5366407679461439 0.7217034139335898 0.4704768427015637 1.0 0.7825023189104643 5 P09429 1 +Positive regulation of substrate adhesion dependent cell spreading 0.429450833707878 0.7206961816910854 0.4710964621812148 1.0 0.7826197239321985 17 P46108,O14786,Q99828,Q13418 4 +Negative regulation of erad pathway 0.6932518572367646 0.720495488190651 0.4712199766541149 1.0 0.7826197239321985 3 Q04323 1 +Humoral immune response mediated by circulating immunoglobulin 0.6939988116458776 0.7202350947449185 0.4713802593826923 1.0 0.7826197239321985 2 Q9UQ84 1 +Negative regulation of interleukin 12 production 0.6939988116458764 0.7202350947449135 0.4713802593826954 1.0 0.7826197239321985 2 Q8WXW3 1 +Protein k29 linked ubiquitination 0.6924694103563434 0.7179869566725489 0.4727653292197786 1.0 0.7843254314269115 3 Q96J02 1 +Polysaccharide biosynthetic process 0.4369844410856806 0.7174878673850472 0.4730731199665938 1.0 0.7846339329104313 14 O43505 1 +Regulation of translation at synapse modulating synaptic transmission 0.5778919259693607 0.7169844335570214 0.4733837016924471 1.0 0.7847575578964006 4 P06730 1 +Secretory granule localization 0.6920723062672031 0.716714933503035 0.4735500095280169 1.0 0.7848354655266554 3 O60763 1 +Regulation of macrophage chemotaxis 0.5775648963611446 0.7158562519982616 0.4740801140434392 1.0 0.7851205916862395 4 P28482,P30046 2 +Regulation of macrophage migration 0.5775648963611446 0.7158562519982616 0.4740801140434392 1.0 0.7851205916862395 4 P28482,P30046 2 +Negative regulation of cellular response to growth factor stimulus 0.4425690700687222 0.714757346257793 0.4747589957509341 1.0 0.7853897958610458 13 Q96TA1,O94813,Q8N0X7,P46934 4 +Male meiosis i 0.6922162804515806 0.7140625382487277 0.4751885093554504 1.0 0.7853897958610458 2 Q15645 1 +Negative regulation of mapk cascade 0.3981411268535446 0.7134682895594877 0.4755560287191465 1.0 0.7853897958610458 33 Q96KB5,Q12959,P04062,Q53EL6,P78318,P15311,Q13526,P43034,Q14118,O75832,O00459,Q99956,Q96J02 13 +Regulation of proteasomal protein catabolic process 0.3603490318534786 0.7109368545949093 0.4771233666355661 1.0 0.7875828119771026 74 Q96KB5,P04062,P62913,Q9BW61,P60520,O00560,Q12834,Q06787,Q9GZP4,Q92530,P49768,P08238,P78559,Q04323 14 +Positive regulation of glial cell differentiation 0.4878493197242921 0.7074917494315041 0.4792609381297974 1.0 0.7893286056629463 8 Q15382,Q14118 2 +Regulation of production of molecular mediator of immune response 0.4074323232668256 0.7071727111977708 0.4794591546865085 1.0 0.7894574016340058 26 P02786 1 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.5096845696699597 0.7049553218808424 0.4808380406046137 1.0 0.7915296874617491 6 Q9BRG1,Q9H444 2 +Cellular response to oxygen containing compound 0.4235526040456485 0.704445583318282 0.4811553271359021 1.0 0.7916557633566694 211 Q06481,P01130,Q9H1E3,P26583,Q14118,Q5KU26,P05067,Q99538,Q9BSK2,Q07954,P49768,Q15043,P33527,Q92542,O94813,Q9Y4G8,O00459,Q99720,Q8WTV0,O95831,Q8N122,P09429,Q53EL6,Q96QD8,Q9UQB8,P23396 26 +B cell activation involved in immune response 0.4292974114336775 0.703929212999797 0.4814768577865287 1.0 0.791986689302272 16 P02786,P13051,Q9UQ84 3 +Protein containing complex disassembly 0.3544654782957518 0.7025363061421346 0.4823447682497825 1.0 0.7930459596287457 101 Q9UQN3,Q9H444,Q9Y3E7,O15344,Q9NYL9,Q9Y5B9,P47756,P61221,P48681,P58546,P53990,P16949,Q99828,P23528,Q66K74,P62829,Q9UEU0,P46821,Q99816,Q9NRR5,P13473,Q8WUX9,P54920,P56962,P15170,Q08945,P33176,P35611,P52907,P62495,P51809,P63241,Q6IBS0,P78559,P29372,P04062,O14976,Q96AX1,Q9H9C1,O75844,Q01105,Q13137,O75083 43 +Positive regulation of cell morphogenesis involved in differentiation 0.4039062176688555 0.7016216359049924 0.4829151550871291 1.0 0.7936077278629908 27 Q13418,Q14444,Q9UJU6,P43034,P46108,Q9UQB8,O14786,Q99828 8 +Positive regulation of viral life cycle 0.4859334425007439 0.6997628554383483 0.4840754153820183 1.0 0.7944730744468356 8 O60684,Q06787 2 +Regulation of protein containing complex assembly 0.3598123932771721 0.6994395361242501 0.4842773871958123 1.0 0.7946062990706046 108 Q15691,P19525,Q9NYL9,Q9UJU6,P17931,Q06124,P47756,P07737,Q16512,P62993,P58546,P23381,P02786,P16949,P04350,Q96F07,Q6VMQ6,P46821,Q9NR31,Q07812,O15143,P54920,O95429,Q14247,Q12959,Q02790,P63000,P35611,O94813,P52907,Q04637,P07900,P06400,Q6IBS0,Q7Z460,Q9NZM5,Q9UNE7,Q9NWS0,P35080,P04062,P09429,P62333,P36405,Q14203,Q9UQB8,P23396 46 +Regulation of ras protein signal transduction 0.3972750011106925 0.6990066572032878 0.4845478704621886 1.0 0.7946536753678077 32 P05556,O75955,Q9Y624,P46108,P52565,Q04721,Q9Y6N7,P16949,O14786 9 +Pyrimidine nucleoside triphosphate biosynthetic process 0.4854163822595435 0.6976800303401653 0.4853773195272679 1.0 0.7956172459133736 8 P17812,Q05682,Q9NRF8,Q9BZX2 4 +Regulation of map kinase activity 0.4168326110921325 0.6956785648875303 0.4866301522657461 1.0 0.7960724377146347 20 P23396,Q53EL6,P04062,Q9Y6N7 4 +Negative regulation of ion transmembrane transport 0.4271893314353779 0.6929283372317894 0.4883545253158483 1.0 0.7973184580609706 16 Q06787,O95747,Q9Y376,P46934,Q96PU5,O75915,P62942 7 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.5707580585787949 0.6924976689595604 0.4886248492821081 1.0 0.7975566611625068 4 O75312 1 +Retrograde transport vesicle recycling within golgi 0.5285164898333614 0.6923053906088792 0.4887455655347961 1.0 0.7975566611625068 5 Q14746,Q8TBA6 2 +Clathrin dependent endocytosis 0.4270335974925032 0.6921165135623746 0.4888641620260303 1.0 0.7975566611625068 16 O14976,Q5VW38,P09496 3 +Steroid biosynthetic process 0.3780267294726786 0.6916346307920844 0.4891668079661861 1.0 0.7975583775414601 42 Q13510,Q14739,Q9UBM7,Q16850,Q15392 5 +Exocytosis 0.3488598143129812 0.6915341006662028 0.4892299585202335 1.0 0.7975583775414601 82 Q9Y3E7,O95219,O00560,O15126,Q16512,O60645,Q8TAG9,O43760,Q92905,Q4J6C6,P35579,P49755,Q9UEU0,O14964,P49768,P54920,P56962,Q12765,P11279,Q06787,Q7L0J3,Q9UNH7,P11233,Q15833,Q9UPT5,P35080,P11274 27 +Establishment of pigment granule localization 0.6824380959765608 0.686086678914849 0.4926584506239626 1.0 0.8012042429166163 3 Q13561 1 +Regulation of microtubule depolymerization 0.4699009393254211 0.6859771768554487 0.4927275007082441 1.0 0.8012042429166163 9 Q66K74,O15344,P46821,P78559,P29372,Q99828 6 +Regulation of striated muscle contraction 0.4283950582144543 0.6858540259656873 0.492805163703349 1.0 0.8012042429166163 15 Q02487 1 +Glycoprotein biosynthetic process 0.3690694889090669 0.6854793707043328 0.4930414739470716 1.0 0.8013117474918646 59 Q9NQX7,Q15643,Q92542,O15118,Q7LGA3,O43505,Q9HC07,Q10472,O60476 9 +Striated muscle cell development 0.4576190573457011 0.6814205382147517 0.495605430847867 1.0 0.80396856328416 10 P05556 1 +Regulation of macroautophagy 0.3680130479037519 0.6804033303915588 0.4962491128492767 1.0 0.8043953876627407 60 Q9H2M9,P04062,O95219,O15118,Q6UWE0,Q93050,Q9Y6K9,Q15382,Q6PKG0,Q13137 10 +Sphingolipid biosynthetic process 0.4272307800420557 0.6799410806889961 0.4965417685264639 1.0 0.8043953876627407 15 Q13510 1 +Transmembrane transport 0.428288244430681 0.6798522287141181 0.4965980322901044 1.0 0.8043953876627407 228 Q9NV96,Q6PCB8,Q06481,P30825,Q13423,Q9BXP2,P05067,O00400,Q8IXU6,Q9C0H2,P05556,Q99523,P22466,P08183,O43772,Q9H2V7,Q9UHG3,Q15043,P33527,P51790,Q7L0J3,Q96PU5,Q8WTV0,O95831,P06756,Q99595,P04062,O60830,P27105,Q96QD8,O75844,Q9H2J7,P08195 33 +Actomyosin structure organization 0.3709859019953899 0.6798455517888607 0.4966022604588613 1.0 0.8043953876627407 51 Q9NYL9,Q16527,P07737,Q16512,Q15417,P16949,P05556,P35579,P35580,Q9H0H5,O95429,P63000,Q9Y6W5,Q13177,P10644,P35080,Q9Y624,Q08722,O14786 19 +Tight junction organization 0.4112006104015693 0.6792998628307777 0.4969478833421634 1.0 0.8047064230548641 22 Q9Y624 1 +Negative regulation of protein targeting to mitochondrion 0.6802377414561676 0.679156119204985 0.4970389475329755 1.0 0.8047064230548641 3 O95429,O95817 2 +Dendritic spine maintenance 0.6801640913416418 0.6789245680394413 0.497185658085991 1.0 0.8047458806322956 3 Q14247 1 +Cell cell adhesion mediated by cadherin 0.5243073858103369 0.6772117214686132 0.4982716318085236 1.0 0.8057027813327656 5 P19022 1 +Regulation of cell population proliferation 0.4322845462730193 0.6763490925785719 0.4988190304672579 1.0 0.8061994059984331 240 P23396,Q06481,P30825,O00560,P26583,P67870,P84095,P05067,Q9Y6N7,P02786,Q99538,Q9NPF0,P55209,Q9BSK2,P05556,P22466,P49459,Q6YHK3,P19022,Q13641,Q9Y4G8,Q86VI3,P11047,Q32P28,Q15392,P04439,P10644,P06756,Q8N122,P09429,Q53EL6,P07942,O75844,Q08722,O14786 35 +Regulation of sodium ion transport 0.4133601843683505 0.6758641410695017 0.4991269065791748 1.0 0.8064988433991186 20 Q12959,O43865,Q9UHD1,P27105,O95747,P46934,O43707,Q04917,P46939,P54709,O14745,Q96PU5 12 +Skeletal muscle tissue regeneration 0.5013607196348748 0.6738303442617383 0.5004191806962985 1.0 0.8071989628789239 6 Q7Z4V5,Q14118 2 +Embryonic organ morphogenesis 0.3967687251827112 0.6734928336287659 0.5006338064200699 1.0 0.8073471877007158 28 Q12959,Q14651,P54802,O95747,Q04721,P63173,P29317,P49768,P11274,Q13308,Q9Y366 11 +Response to oxygen levels 0.3676426552606666 0.6727536566705172 0.5011040254145867 1.0 0.8079074213669488 59 P78536,Q15118,Q13526,Q15904,P02786,P55786,O95831,P11166 8 +Regulation of protein phosphorylation 0.4057888230539438 0.6702650495369236 0.5026888429322325 1.0 0.8097876642104064 181 O60271,P23396,P54619,Q96KB5,Q9P287,O00560,Q13526,P67870,Q14118,P05067,Q9Y6N7,P02786,Q9H223,Q96A49,Q99828,P32780,P78536,P04792,Q07954,O00410,O95373,Q07812,P49768,P08238,Q96B36,P51114,Q6YHK3,O94992,O95429,Q12959,Q02750,O94813,O75955,Q9Y4G8,P07900,Q86VI3,Q06787,Q9Y376,Q13177,Q8ND04,Q9NWS0,P10644,Q8N122,P04062,Q53EL6,Q15375,Q86Y37,O14786 48 +Negative regulation of alpha beta t cell activation 0.5639321453739999 0.6693205661404177 0.5032910103635768 1.0 0.8102418664149801 4 P09429 1 +Endothelial cell development 0.4101323844315102 0.6644769107206618 0.5063851219861362 1.0 0.8130342524834767 21 Q9Y624 1 +Negative regulation of cellular component organization 0.4018900525982458 0.6638022871528573 0.5068168616563291 1.0 0.8132823018387995 175 Q15691,O94898,P01130,P17931,O00560,Q9H6U6,P47756,P05067,P18887,P02786,P16949,P04350,P49768,P60983,Q9UKS6,Q9NQX7,O94813,Q8N0X7,Q9Y4G8,Q13177,P29372,P06756,Q99536,P04062,P09429,Q6UWE0,Q9Y624,P43034,Q9UNF0,Q15375,O14786 31 +Biological process involved in interspecies interaction between organisms 0.4426340047447165 0.6620476461943705 0.5079406866880876 1.0 0.813348061595482 284 O15347,Q9Y3E7,P13591,Q06481,P01130,O00584,Q9H1E3,P61916,P26583,Q14118,Q5KU26,Q9BTY2,Q9Y6K9,P11717,P02786,P78310,P16949,Q14108,P05556,Q12899,P78536,O75179,Q9NUQ8,O94992,O15118,P11279,Q13309,Q06787,P63241,P13693,Q9Y3Z3,P04439,Q8WTV0,Q08722,P06756,P01889,P09429,Q53EL6,O43657,Q9Y624,P27105,Q92692,P35613,O75844,P29317,Q9UQB8,P10321,Q13137,P08195,O14786 50 +Meiotic cell cycle checkpoint signaling 0.6746165884036761 0.6615648227032371 0.508250158199264 1.0 0.813645544082443 3 Q08J23 1 +Muscle contraction 0.3689252411197259 0.6600457409848796 0.5092244765329581 1.0 0.8140166723289911 45 Q14126,P10253,Q02487 3 +Animal organ formation 0.4971402374614456 0.6581902339006732 0.5104158994542685 1.0 0.8144993772978125 6 Q02750,Q9Y6N7 2 +Proteoglycan biosynthetic process 0.5189253144648738 0.6580564309376712 0.5105018707765716 1.0 0.8144993772978125 5 Q7LGA3 1 +Regulation of sodium proton antiporter activity 0.6734026745913828 0.6577878758109164 0.5106744461472259 1.0 0.8144993772978125 3 O14745,O43707 2 +Trophoblast cell migration 0.672849950315202 0.6560707729712082 0.5117785886123394 1.0 0.8157207550016885 3 Q7Z739 1 +Postreplication repair 0.4354605016982148 0.6552146609439901 0.5123295563109875 1.0 0.8164011195285068 12 P49459,P49005 2 +Gmp biosynthetic process 0.4402740542150827 0.6549735146156995 0.5124848065770558 1.0 0.816450728424285 11 P07741,P22102,P49915,P00492,O15067,Q06203,P55263,P31939,P30566,P22234 10 +Collagen fibril organization 0.4623805156720647 0.654672552345994 0.5126786008116362 1.0 0.8165617036656037 9 Q9H9C1,O75718,Q92791,P13674 4 +Organonitrogen compound catabolic process 0.4426025699302368 0.654107185876631 0.5130427522164949 1.0 0.8167461820135777 391 P42892,Q9Y3E7,O14773,Q9UIQ6,O94898,P01130,P15586,Q6GQQ9,O75503,P28074,O00560,Q13526,P06280,Q9GZP4,P50897,Q99538,P06865,Q8TEY7,P04066,Q07954,O14967,Q13438,P54802,P60520,P13473,Q8NCC3,P10619,P49459,Q92530,P16278,P60900,Q9H773,P17900,P53634,P49721,Q9UHG3,P49768,P33527,Q13510,P28070,Q13309,Q9BW61,Q06787,P28072,Q9Y3Z3,P07686,Q9UJ14,Q96PU5,P78559,Q8WTV0,Q9NUM4,P09960,P04062,Q9UMY4,P62913,Q16850,O75844,P55786,P13051,O43847 60 +Cardiac cell development 0.4220614035000744 0.6537768435122195 0.5132555874149445 1.0 0.8168873104320118 15 P78310,O75844 2 +Progesterone receptor signaling pathway 0.5166051989359705 0.6498509397183675 0.5157885109777798 1.0 0.8190667050159691 5 Q05086,P46934 2 +Regulation of protein glycosylation 0.6732026143790919 0.649453991977456 0.5160449751864198 1.0 0.8190667050159691 2 Q08379 1 +Positive regulation of protein glycosylation 0.6732026143790919 0.649453991977456 0.5160449751864198 1.0 0.8190667050159691 2 Q08379 1 +Positive regulation of vacuole organization 0.4849667987528656 0.6476536265840586 0.517209004098985 1.0 0.8190667050159691 7 Q9H2M9,O95219 2 +Renal sodium ion transport 0.6726084373143264 0.6474732427231713 0.5173257064384957 1.0 0.8190667050159691 2 O14745 1 +Renal absorption 0.6726084373143264 0.6474732427231713 0.5173257064384957 1.0 0.8190667050159691 2 O14745 1 +Cellular response to extracellular stimulus 0.3674152342600057 0.6471163807632475 0.5175566243758234 1.0 0.8190667050159691 48 Q8TEY7,Q8N122,Q02487,P04062,P13473,Q96QD8,Q9H773,O95831,P11166 9 +Cell killing 0.4081592539265025 0.6462986437300458 0.5180859660644443 1.0 0.8190667050159691 20 P11279,P04439,P53634 3 +Regulation of rna binding 0.4713584869854434 0.6415868074161509 0.5211415010538771 1.0 0.8214029790246024 8 Q9H1E3 1 +Regulation of skeletal muscle fiber development 0.6708259061200307 0.6415456365025279 0.5211682404253359 1.0 0.8214029790246024 2 Q96TA1 1 +Corpus callosum development 0.6680970189237857 0.6413742758641401 0.5212795420150198 1.0 0.8214029790246024 3 P43034 1 +Columnar cuboidal epithelial cell development 0.4711992186574651 0.640957579330976 0.5215502443949629 1.0 0.8214029790246024 8 P19022 1 +Glycerol ether metabolic process 0.4823911457129406 0.6378979798799449 0.5235400928511371 1.0 0.8229967332060941 7 Q7L5N7 1 +Synaptic transmission dopaminergic 0.5131594247100808 0.6377242687081873 0.5236531847914572 1.0 0.8229967332060941 5 O75955 1 +Glycosylation 0.3651015524970333 0.6371134343394382 0.5240509584244544 1.0 0.8233119666864248 55 Q14746,Q15643,P04062,O15118,O75503,O43505,Q9HC07,P49768,Q10472,O60476 10 +Cellular response to testosterone stimulus 0.6693404634581173 0.6366228936368549 0.5243705092596098 1.0 0.8234206755573438 2 P26038 1 +Negative regulation of cilium assembly 0.6662704309063905 0.6357597601870965 0.5249330188820549 1.0 0.8240203985633798 3 P50395,P27816 2 +Positive regulation of ubiquitin protein ligase activity 0.5125686419290522 0.6356524687779471 0.5250029629642938 1.0 0.8240203985633798 5 Q16763,Q12834,Q96GX5 3 +Cytoplasmic translational initiation 0.4049969548146477 0.6348350008505511 0.5255360330982386 1.0 0.8244636359933731 21 Q15056,P55010,A9UHW6,Q9NR50 4 +Negative regulation of phosphatase activity 0.4301453034612953 0.6308010032929025 0.5281706473125802 1.0 0.8273561574344347 12 O95429,P62942 2 +Maintenance of cell polarity 0.4883988574560115 0.6261229663298403 0.531234289397637 1.0 0.8301541604391321 6 Q8WUM4,O75083,Q03001 3 +Protein k63 linked ubiquitination 0.4141916876453533 0.6256247217343783 0.5315611195808896 1.0 0.8301541604391321 16 Q16763,Q9C0C9,P61088,P46934,Q96J02,Q96FW1 6 +Positive regulation of innate immune response 0.3866148431521676 0.6253948484924725 0.5317119423503405 1.0 0.8301541604391321 32 O94992,P09429,P11279,P26583,Q92692,Q13177,Q9BUI4 7 +Cellular response to acid chemical 0.4182925809548277 0.6250769001009312 0.5319205880871132 1.0 0.8301541604391321 14 Q8N122,Q9UQB8 2 +Homeostasis of number of cells 0.3596075952604945 0.6244709057709953 0.5323183716528215 1.0 0.8301541604391321 64 P19022,P04062,Q92542,P09429,P26583,O00115,P38571 7 +Cerebral cortex radially oriented cell migration 0.4661568779068925 0.6211150351895277 0.534523937382215 1.0 0.8324096733191786 8 P07942 1 +Telencephalon glial cell migration 0.4661568779068925 0.6211150351895277 0.534523937382215 1.0 0.8324096733191786 8 P07942 1 +Regulation of potassium ion import 0.6608040331851783 0.6190714406512846 0.5358692965467733 1.0 0.8334838469085564 3 Q12959 1 +Response to alcohol 0.3788272739190417 0.6174148483902072 0.5369611306235595 1.0 0.8338161244001061 37 O94813,Q15126,O95831,P16278 4 +Regulation of myoblast fusion 0.6602013825982568 0.6172422762871381 0.5370749344912207 1.0 0.8338161244001061 3 Q9H4M9 1 +Positive regulation of myoblast fusion 0.6602013825982568 0.6172422762871381 0.5370749344912207 1.0 0.8338161244001061 3 Q9H4M9 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.6602013825982568 0.6172422762871381 0.5370749344912207 1.0 0.8338161244001061 3 Q9H4M9 1 +Regulation of syncytium formation by plasma membrane fusion 0.6602013825982568 0.6172422762871381 0.5370749344912207 1.0 0.8338161244001061 3 Q9H4M9 1 +Vesicle mediated transport to the plasma membrane 0.3632210268438077 0.6166124152887111 0.53749040353989 1.0 0.834264245985228 53 Q9UMY4,O95219,Q07960,Q8N3F8,Q15904,Q96L92,P42566,Q9H223,Q9H4M9,Q4J6C6 10 +Thioester biosynthetic process 0.3984651739298682 0.6134210694678803 0.5395979581061838 1.0 0.8357606235984171 23 Q9UMR5 1 +Plasma membrane tubulation 0.4847409914072101 0.6128425402982344 0.5399804595017628 1.0 0.8361098576096192 6 Q9UNF0,Q8N3F8 2 +Regulation of guanyl nucleotide exchange factor activity 0.5457668976492787 0.6089630959673612 0.5425489003921622 1.0 0.8366713111010762 4 P16949 1 +Regulation of secondary metabolic process 0.6573149534733242 0.6085113481380396 0.5428483817776502 1.0 0.8366713111010762 3 Q9Y4G8 1 +Establishment of protein localization to plasma membrane 0.3939550277292728 0.6083183713934491 0.5429763387447526 1.0 0.8366713111010762 25 Q15904 1 +Negative regulation of protein serine threonine kinase activity 0.4022456921578206 0.6081466496588226 0.543090214797231 1.0 0.8366713111010762 19 O94992,P04062,P10644 3 +Regulation of neurotrophin trk receptor signaling pathway 0.6601307189542557 0.6064554345634643 0.5442123671180363 1.0 0.8366713111010762 2 Q96F07 1 +Positive regulation of neurotrophin trk receptor signaling pathway 0.6601307189542557 0.6064554345634643 0.5442123671180363 1.0 0.8366713111010762 2 Q96F07 1 +Receptor localization to synapse 0.4246413441909867 0.6057120848910538 0.5447059577173465 1.0 0.8366713111010762 12 Q14168,O15400,Q14118 3 +Cardiac muscle tissue development 0.386424037913067 0.6056231422523777 0.5447650312905665 1.0 0.8366713111010762 28 Q14126,P05556,O75844,P78310,P10644 5 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4196455400737279 0.605464847941155 0.5448701744569957 1.0 0.8366713111010762 13 O43657 1 +Positive regulation of lipid storage 0.5036008186969105 0.6044778692045918 0.5455259784446413 1.0 0.8366713111010762 5 Q8WTV0,Q9H4M9 2 +Response to oxygen containing compound 0.4387180671310237 0.6031479858019362 0.5464102463923857 1.0 0.8366713111010762 290 Q06481,P01130,Q9H1E3,P26583,Q14118,Q5KU26,P05067,P11717,P02786,Q99538,Q9BSK2,Q99523,P78536,Q07954,P22466,Q9NR50,P16278,P49768,P49321,Q15043,P33527,Q92542,O94813,Q15126,Q9Y4G8,O00459,Q99720,Q8WTV0,O95831,P11166,Q8N122,P04062,P09429,Q53EL6,Q96QD8,P35613,Q9UQB8,P23396 38 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6589423648247251 0.6026084178966326 0.5467692190490778 1.0 0.8367089419742341 2 Q9UNN5 1 +Regulation of cilium assembly 0.4004092826630616 0.6025253000430673 0.5468245274471317 1.0 0.8367089419742341 20 Q9P2S5,Q15555,P50395,P42858,Q9BXI6,Q16181,Q8TC07,Q9UHD8,Q4KMP7,Q66K14 10 +Microtubule based movement 0.3402610107034342 0.6014057423958682 0.5475697748876067 1.0 0.8374052412760641 82 Q66K74,Q9Y678,P04792,P11279,P78318,P43034,Q14203,Q2M1P5,P05067,Q15154,Q8TD16,P78559,Q14168,Q13409 14 +Regulation of cell cycle g1 s phase transition 0.3666403391496983 0.6012679990457606 0.5476615001474046 1.0 0.8374052412760641 42 Q8N6R0,Q8N122,P78536,Q06481 4 +Autophagosome organization 0.3837978734133043 0.6000509322313723 0.5484722922736589 1.0 0.8377290172107887 31 Q9H444,Q9H2M9,Q9UNZ2,P04062,O95219,P60520,Q6UWE0,Q9ULC3,P49768,Q86Y82 10 +Anterograde dendritic transport 0.6543833580980695 0.5996952687183104 0.5487093419849673 1.0 0.8377290172107887 3 Q14254,P33176 2 +Regulation of exosomal secretion 0.4604905911839371 0.5990063899565912 0.5491686234424353 1.0 0.8381510916483387 8 Q9Y3E7,O00560,Q8WUM4,O14964 4 +Histone h4 r3 methylation 0.6574569221628119 0.5978146808728049 0.5499635937663401 1.0 0.8384925061532754 2 O14744 1 +Positive regulation of protein localization to nucleus 0.3742099302579325 0.5960274699287355 0.5511568757131173 1.0 0.8392935749889416 38 O75312,P49768,O00459,Q96D46,P02786 5 +Long chain fatty acid transport 0.4173739921481634 0.5948146028573706 0.5519674052787447 1.0 0.8395844087551599 13 O43772 1 +Regulation of animal organ morphogenesis 0.4707072022802648 0.5941522256963331 0.5524103028352931 1.0 0.8395921839303507 7 Q9Y6N7 1 +Positive regulation of cellular component biogenesis 0.3615056751624929 0.5929129453144844 0.5532394140437025 1.0 0.8404639412423729 123 Q15691,P23396,O95219,P17931,O00560,Q9H6U6,Q14118,P07737,P62993,P02786,Q13283,Q6VMQ6,O14964,Q07812,O95429,Q14247,Q12959,P63000,Q9HBH5,O75955,Q13641,P07900,Q06787,Q9Y6W5,Q6IBS0,Q9UNE7,Q08722,P11233,Q9NWS0,P35080,Q9P2S5,Q9H2M9,Q6UWE0,P29317,Q16181,Q14203,Q9UQB8,O14786 38 +Regulation of ossification 0.4587689449505978 0.5923304577592323 0.5536293241510029 1.0 0.84066798113234 8 O75844 1 +Regulation of growth 0.3684426947867588 0.5896886573686385 0.5553994009951664 1.0 0.8425777813067815 133 O60271,O00560,Q5BJF2,P05067,Q9Y4B6,P50897,P02786,Q99538,Q9BSK2,P78536,O94813,Q8N0X7,Q7Z4V5,Q96PU5,O75312,Q8N122,O43598,P43034,Q15375,O75844,O14786 21 +Cytoplasmic sequestering of nf kappab 0.5396189641139252 0.5890098175317632 0.5558546878141877 1.0 0.8430740457555284 4 Q9UN86,O75832 2 +Protein localization to endoplasmic reticulum exit site 0.4988308451638136 0.5881151492162177 0.5564550053728068 1.0 0.8437900012315176 5 Q9UHQ4 1 +Positive regulation of response to biotic stimulus 0.3746585017658174 0.5868012768199289 0.5573371791894959 1.0 0.8441199077142055 37 O94992,P09429,O75179,P11279,P26583,Q92692,Q13177,Q9BUI4 8 +Phototransduction 0.5380499405469568 0.5839586462803052 0.5592481348183238 1.0 0.8451175816542397 4 P29992,O96017,Q15555 3 +Detection of light stimulus 0.5380499405469568 0.5839586462803052 0.5592481348183238 1.0 0.8451175816542397 4 P29992,O96017,Q15555 3 +Regulation of myeloid cell apoptotic process 0.4762106205574801 0.5822115246183845 0.5604242115838847 1.0 0.8459079990970917 6 P42771,P78536 2 +Regulation of ubiquitin dependent protein catabolic process 0.3565947441096883 0.5821876843708346 0.5604402679543339 1.0 0.8459079990970917 61 Q96KB5,O00560,Q12834,O75832,P62829,Q9NRR5,P49768,P08238,Q04323,Q9BW61,P54578,Q05086,P46777,Q9NZM5,P54727,Q9UNE7,P78559,Q9Y4X5,P04062,O15372,P62913,P45974,Q9Y5A7 23 +Protein k48 linked deubiquitination 0.4143820686556304 0.5808437303723663 0.5613457791413392 1.0 0.8459079990970917 13 Q8TEY7,Q9H8M7,Q6GQQ9,Q96FW1,Q04323 5 +Regulation of cytoskeleton organization 0.3731479636260285 0.5805753226712644 0.5615267080104314 1.0 0.8459079990970917 141 Q9UQN3,Q9H444,Q15691,P23396,Q9Y3E7,Q9NYL9,P15311,Q9UJU6,Q9H6U6,P84095,P47756,P07737,Q16512,P62993,P48681,P16949,Q99828,Q66K74,P04350,Q07954,P46821,Q9UHV9,Q9Y5K6,Q8WUX9,Q8WUM4,Q04721,O15143,P60983,O95429,Q14247,Q12959,Q02790,P63096,P63000,Q15555,O94813,Q86VI3,P52565,Q9Y6W5,Q6IBS0,Q13177,Q8TD16,P78559,P29372,P35080,P28482,Q9Y624,P43034,P36405,P46108,Q08722,Q14203,Q9UQB8,O14786 54 +Export from cell 0.3790826836608708 0.5801000010737346 0.5618471830400409 1.0 0.8459393628369613 150 Q9Y3E7,O95219,O00560,P20645,P50897,O43760,Q4J6C6,P22466,P08183,Q9UEU0,P49768,P33527,P11279,Q06787,Q32P28,Q7L0J3,P11233,Q9Y678,Q16850 19 +Second messenger mediated signaling 0.3825077555643708 0.5800823474647405 0.5618590872962426 1.0 0.8459393628369613 28 O75844,P22466 2 +Positive regulation of actin filament polymerization 0.414091488182307 0.5794903952945477 0.562258325546638 1.0 0.8463467426649393 13 O95429,Q14247,Q12959,P07737,P62993,Q9UQB8 6 +Positive regulation of ubiquitin dependent protein catabolic process 0.3806578733994558 0.5788092940216177 0.5627178592883222 1.0 0.8466509785907098 31 Q9Y4X5,P04062,Q9BW61,Q12834,O75832,Q9NZM5,P49768,Q9UNE7 8 +Regulation of protein neddylation 0.6471000266784197 0.5780234323447404 0.5632482991971657 1.0 0.8471126124159299 3 P62913 1 +Exploration behavior 0.5361837618586923 0.5779731620473944 0.5632822387818908 1.0 0.8471126124159299 4 Q9HB07 1 +Methylguanosine cap decapping 0.4949487805325169 0.5749164509783079 0.5653478033834549 1.0 0.8489354588107659 5 Q86TB9,Q96C86 2 +Rna decapping 0.4949487805325169 0.5749164509783079 0.5653478033834549 1.0 0.8489354588107659 5 Q86TB9,Q96C86 2 +Execution phase of apoptosis 0.4041093604376171 0.5741429059161155 0.5658711010115525 1.0 0.8490648043918778 16 O00115 1 +Macrophage apoptotic process 0.6494355317884807 0.5722239291758319 0.5671702780614292 1.0 0.8496179459214088 2 P42771 1 +Regulation of macrophage apoptotic process 0.6494355317884807 0.5722239291758319 0.5671702780614292 1.0 0.8496179459214088 2 P42771 1 +Regulation of protein targeting to membrane 0.4315080147061441 0.5703769083901403 0.5684220879591464 1.0 0.8505642617368664 10 Q9Y3D6,P27105 2 +Regulation of transcription regulatory region dna binding 0.4164324262508933 0.5686898970499082 0.569566605223017 1.0 0.8518892972162361 12 O75844 1 +Positive regulation of protein export from nucleus 0.4205771706107728 0.5683672931897235 0.5697855941997858 1.0 0.8520231049434397 11 Q92688 1 +Peptidyl serine modification 0.3534654630036627 0.5680874480733263 0.569975590341878 1.0 0.8521135075611075 64 Q8N122,O95429,Q13177,Q9BV86,Q13418,P08238,P07900,P05067,Q9Y376,Q07812,P02786,Q10472 12 +Regulation of substrate adhesion dependent cell spreading 0.3937018776247518 0.5649542719143477 0.572104867723098 1.0 0.8526083944421754 20 P46109,P50570,Q07021,P63000,Q13418,P46108,Q96AC1,O43707,O14786,Q99828 10 +Terminal button organization 0.6470588235294196 0.5647396728316805 0.5722508454640014 1.0 0.8526083944421754 2 Q96QK1 1 +Vesicle fusion to plasma membrane 0.6470588235294195 0.5647396728316798 0.5722508454640018 1.0 0.8526083944421754 2 Q12846 1 +Negative regulation of cellular protein catabolic process 0.3776973086180024 0.5642531970138095 0.5725818286982172 1.0 0.8527877109634536 32 Q96KB5,P62913,P60520,O00560,Q92530,P49768,P08238,P78559 8 +Positive regulation of catecholamine metabolic process 0.6421991084695405 0.5636321263928412 0.5730045181573988 1.0 0.8527877109634536 3 P00492,Q96QK1 2 +Positive regulation of cellular amine metabolic process 0.6421991084695405 0.5636321263928412 0.5730045181573988 1.0 0.8527877109634536 3 P00492,Q96QK1 2 +Roof of mouth development 0.4708077482564555 0.5630711160957093 0.573386458862434 1.0 0.8527877109634536 6 O95747,Q92688 2 +Cellular response to molecule of bacterial origin 0.382306828554887 0.5628486044905027 0.5735379801310914 1.0 0.8527877109634536 27 Q8WTV0,P09429,Q53EL6 3 +Cardiac muscle cell differentiation 0.3990630400856677 0.5601126251847925 0.5754026194307755 1.0 0.8539623598515986 17 P78310,O75844 2 +Branching involved in mammary gland duct morphogenesis 0.6405749099035281 0.5588977433835917 0.5762315095892807 1.0 0.8539970706267687 3 P29317 1 +Ribonucleoside monophosphate catabolic process 0.530132212147794 0.5587346139856982 0.5763428524887275 1.0 0.8539970706267687 4 Q9NRG1,P00492 2 +Purine nucleoside monophosphate catabolic process 0.530132212147794 0.5587346139856982 0.5763428524887275 1.0 0.8539970706267687 4 Q9NRG1,P00492 2 +Phosphorylation of rna polymerase ii c terminal domain 0.6404213476468527 0.5584510380834595 0.5765364295131894 1.0 0.8539970706267687 3 P32780 1 +Free ubiquitin chain polymerization 0.6449792038027411 0.5582287352358535 0.576688201235042 1.0 0.8539970706267687 2 Q16763 1 +Purine nucleotide transport 0.4137180744837124 0.556560841988476 0.5778275141719396 1.0 0.8551067240096779 12 O00400 1 +Postsynaptic specialization organization 0.5288272327487901 0.5546209692409562 0.579153943065519 1.0 0.8566842000191104 4 P19022 1 +Mitotic spindle midzone assembly 0.5286604141260696 0.5540960247439578 0.5795131305542189 1.0 0.8567875914038098 4 Q9H0H5 1 +Cellular response to biotic stimulus 0.3716546797695226 0.5539593167925624 0.5796066886160411 1.0 0.8567875914038098 36 O75844,Q8WTV0,P09429,Q53EL6 4 +Regulation of adherens junction organization 0.6431966726084453 0.5526763609494639 0.5804850430815953 1.0 0.85768423632903 2 P35611 1 +Rac protein signal transduction 0.4028368343722703 0.5503640802140687 0.5820696804385368 1.0 0.858680053358308 14 P63000,Q9UJU6,P84095,P46108,Q9Y2I1 5 +Protein repair 0.6420083184789149 0.5489895064128415 0.5830126512253551 1.0 0.8588619816361556 2 P22061 1 +Cellular response to nitrosative stress 0.6420083184789147 0.5489895064128408 0.5830126512253555 1.0 0.8588619816361556 2 P31689 1 +Response to nitrogen compound 0.4236582547874929 0.5483969751904081 0.5834193529561429 1.0 0.8591029871937624 248 Q06481,P01130,Q9H1E3,Q14118,Q5KU26,P05067,Q99538,Q9BSK2,P05556,Q99523,Q07954,P22466,Q13438,O14967,Q9NR50,P49721,Q15043,P33527,Q92542,O15118,O94813,Q9Y4G8,O00459,O95831,P11166,Q8N122,P35613,Q9UQB8,P08195 29 +Positive regulation of signal transduction by p53 class mediator 0.4261483093165249 0.5481638309150428 0.5835794148240794 1.0 0.8591029871937624 10 O94992,P63241 2 +Base excision repair 0.3905180276505548 0.5472346404921389 0.5842175403989551 1.0 0.8593573503143848 20 P29372,P13051,P18887,P23396 4 +Cellular response to xenobiotic stimulus 0.3818297115644736 0.5459825322217071 0.5850779444916445 1.0 0.859742187202377 26 P02786,O00170 2 +Somatic diversification of immunoglobulins 0.3901794764575054 0.5453550667416587 0.5855093377360312 1.0 0.859742187202377 20 P02786,Q9Y3Z3,P13051 3 +Ovarian follicle development 0.4656268525672728 0.5449183194236233 0.5858096961404415 1.0 0.859742187202377 6 Q05086,Q13144,Q07812 3 +Negative regulation of map kinase activity 0.4463363852851022 0.5447397486971772 0.5859325227960748 1.0 0.859742187202377 8 P04062 1 +Positive regulation of collagen metabolic process 0.6405228758170015 0.5443976556442306 0.5861678587049342 1.0 0.859742187202377 2 P08670 1 +Negative regulation of dendritic spine development 0.6405228758170015 0.5443976556442306 0.5861678587049342 1.0 0.859742187202377 2 Q05086 1 +Anoikis 0.4564880249990077 0.5421569710300094 0.5877103746761139 1.0 0.8604868474476227 7 P05556 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.4342978143203111 0.5408515116019441 0.5886099344337312 1.0 0.8607057039062583 9 Q9BW85,O75844,O75832 3 +Regulation of histone h4 acetylation 0.4639128657968598 0.5389578724510543 0.5899159232371609 1.0 0.8609214347717953 6 O75844 1 +Response to inorganic substance 0.3473136970402906 0.5378725426361101 0.5906650456021612 1.0 0.8609214347717953 111 P23396,Q92542,O15118,P05198,Q06787,Q96QD8,P35613,Q9NP58,P05067,P02786,Q99538,Q99720,O95831,P09960,Q96PU5 15 +Positive regulation of secretion 0.3540238874823437 0.536714245091177 0.5914650146881755 1.0 0.8612568469384109 52 P11279,P22466 2 +Positive regulation of map kinase activity 0.412898549063693 0.5353831772843134 0.5923849204626608 1.0 0.8619128526439688 11 P23396,Q9Y6N7 2 +Vesicle organization 0.3423026684948634 0.5349552714764203 0.5926807870661612 1.0 0.8621526354093783 105 Q14108,Q99523,Q9Y3E7,O15400,Q9UEU0,O00560,P43034,Q92692,P51790,Q92734,Q96ED9,P42566 12 +Positive regulation of protein targeting to membrane 0.432669222557314 0.5344232887384713 0.5930487099521087 1.0 0.8621777837427118 9 Q9Y3D6,P27105 2 +Interleukin 1 alpha production 0.6372549019607926 0.5343617391748752 0.5930912848032488 1.0 0.8621777837427118 2 Q96RD7 1 +Positive regulation of interleukin 1 alpha production 0.6372549019607926 0.5343617391748752 0.5930912848032488 1.0 0.8621777837427118 2 Q96RD7 1 +Cardiocyte differentiation 0.386280620759829 0.5340825266892306 0.5932844382802718 1.0 0.8621881398547554 22 P05556,P78310,O75844 3 +Regulation of response to tumor cell 0.6319199904656642 0.5339725125692324 0.5933605517060623 1.0 0.8621881398547554 3 P09429 1 +Blastocyst growth 0.4320850406226721 0.5321226153389221 0.5946410749502542 1.0 0.8630955408258544 9 O75312,P61201,Q9BRX2,Q9BRT9 4 +I kappab kinase nf kappab signaling 0.3531387289935185 0.5316488414742363 0.5949692304418321 1.0 0.863340771666096 54 P04792,Q7Z7H5,Q6GQQ9,O75179,O43657,Q9Y6K9,Q92734,P02786,P62942 9 +Protein catabolic process 0.4339716987713166 0.5314111822578371 0.5951338742418544 1.0 0.863340771666096 298 Q9Y3E7,O14773,Q9UIQ6,Q96KB5,O94898,P01130,Q6GQQ9,P28074,O75503,O00560,Q13526,Q9NYU1,Q12834,Q9GZP4,P50897,Q99538,Q8TEY7,Q07954,O14967,Q13438,P61088,P60520,P13473,P10619,Q96K76,P49459,Q92530,P60900,P49721,P49768,P53634,O60524,Q9UHG3,P08238,Q04323,Q9UKS6,P28070,Q13309,Q9BW61,Q8TCT9,Q99436,Q06787,P28072,Q96PU5,P78559,Q96J02,Q9NUM4,Q9Y4X5,P04062,Q9UMY4,P62913,Q6UWE0,Q16850,O75844,Q86Y37,O43847 56 +Response to nitrosative stress 0.4817127564674476 0.5307631541863009 0.5955829159884976 1.0 0.863340771666096 5 P48507,P48506,P31689,Q99497 4 +Cellular response to muramyl dipeptide 0.6348781937017314 0.5271208237753487 0.5981096868165654 1.0 0.8652662238573493 2 P08670 1 +Establishment or maintenance of cell polarity 0.347465856469296 0.5237927975404076 0.6004226634695515 1.0 0.8670867794297936 66 Q9H4A6,P15311,P84095,A0MZ66,P05556,P35579,P46821,Q14517,Q8WUM4,P08238,Q13308,Q12959,P63000,P07900,P42858,Q03001,Q9UNZ2,Q13418,P43034,P46108,Q96L92,Q14203,Q14168,Q9H6U6 24 +Columnar cuboidal epithelial cell differentiation 0.406026402719864 0.5225207508988621 0.6013078023009049 1.0 0.8674303368379722 12 P19022,Q9P287,P07437 3 +Protein o linked glycosylation 0.3948585208110023 0.5190174646855443 0.6037485623563379 1.0 0.8701704739658174 15 O43505 1 +Negative regulation of receptor internalization 0.4580137760429578 0.5186212384434015 0.6040248955191696 1.0 0.8703060279488772 6 O00560 1 +Protein localization to cilium 0.3958465532437262 0.5171964647500175 0.6050190196357232 1.0 0.8708464837679506 14 Q9UPT5,Q15643,P50395,Q10713,Q9H4M9 5 +Polyol catabolic process 0.4281899402911253 0.5168537248771709 0.6052582729637963 1.0 0.8708464837679506 9 Q9NX62 1 +Regulation of cell morphogenesis involved in differentiation 0.3719479734543354 0.5164078325228844 0.6055695964516046 1.0 0.8708464837679506 30 P63000,Q13418,Q14444,Q9UJU6,P43034,P46108,Q9UQB8,O14786,Q99828 9 +Cell cycle dna replication initiation 0.4571683521713231 0.5157298230005543 0.6060431222749907 1.0 0.8708464837679506 6 P49736,Q9BRX5,P25205,P09884,P33993 5 +Intracellular transport 0.3296697404080854 0.5151838391239508 0.6064245609959222 1.0 0.8711641760714515 594 Q06481,P01130,O75503,P61916,P05067,P11717,P07602,Q14108,Q99523,Q07954,P13473,P10619,O43772,O15118,P11279,Q15904,O43731,Q9NUM4,Q99595,O60830,P27105,O75844,P55786,Q9NV96,O95219,P20645,O00170,Q4J6C6,Q15643,Q9UEU0,Q13438,Q9H173,P39687,Q8NBN3,Q92688,Q96ED9,O15260,Q10713,O00459,Q8N4H5,Q9C0E2,O95831,Q9Y678,Q9BZH6,Q9UMY4,Q96ST2,Q9ULC3,Q8N3F8,P35606,O60684,Q92734,Q96L92,Q9Y3E7,O00560,Q9BXI6,Q9H4M9,Q9H6Z4,P49768,O95429,O15400,Q9H814,Q8TD16,P78559,P42566,O75312,Q9C0C9,Q7Z7H5,P62913,P61970,P43034,P07437,Q9H9C1,Q96D46,Q14203,Q14168,Q08J23,P09496,O60725 78 +Cellular response to peptide hormone stimulus 0.3480361490778322 0.5136537549631368 0.6074940895708458 1.0 0.8714695979255971 63 P07741,Q06481,Q9H1E3,O43865,P62993,P46108,P46060,O00459,Q9UQB8,Q15043,Q96A49,Q9BSK2 12 +Positive regulation of catabolic process 0.3774363569701656 0.5135530027793755 0.6075645448596516 1.0 0.8714695979255971 157 O95219,P01130,Q12834,Q9Y6K9,P05067,Q8NCG7,Q07954,P49768,P53634,Q9UKS6,Q9HBH5,Q9BW61,Q86TB9,Q06787,P67809,Q96PU5,Q96J02,Q9Y4X5,Q9H2M9,P04062,P09429,Q6UWE0,Q7Z739,Q13137,O43847 25 +Cellular response to cadmium ion 0.4763708435050655 0.5133381636015096 0.6077147925499329 1.0 0.8714950742082971 5 P28482,Q9NP58 2 +B cell differentiation 0.3948645920083202 0.512571981361619 0.6082507566753654 1.0 0.8720735565410971 14 O15347,P05556,P78536,Q9Y4B6,Q04721,Q07812 6 +Coronary vasculature development 0.4268905363065979 0.5117881126164368 0.6087993108358116 1.0 0.8724797095158974 9 O14786 1 +Intracellular transport of virus 0.4756001852825018 0.5108440305960653 0.6094602749880385 1.0 0.8728564530527579 5 O60684,Q06787 2 +Germ cell development 0.3622781681031037 0.5076347914665749 0.6117094867309869 1.0 0.8749295992300142 38 Q9Y2W6,P26583,P43034,Q92692,Q9GZP4,Q08J23,P07686,Q96SB4,Q99828 9 +Regulation of receptor internalization 0.4062683060308161 0.5073067450477688 0.6119396066299261 1.0 0.8749295992300142 11 O00560,O75955,Q06787 3 +Cell cell junction assembly 0.3674197030900152 0.5066281587444597 0.6124157468081091 1.0 0.8749295992300142 34 Q9Y624,P29317 2 +De novo amp biosynthetic process 0.4454031538232803 0.5026912911282337 0.6151813335976322 1.0 0.8774788485473529 7 P30520,P22102,Q06203,P31939,P30566,P22234 6 +Positive regulation of cytoskeleton organization 0.3500714737414324 0.50237787188695 0.6154017414853468 1.0 0.8774788485473529 49 Q15691,Q9H6U6,P62993,P07737,Q16512,P48681,Q9UHV9,O95429,Q14247,Q12959,P63000,Q9Y6W5,P35080,P36405,Q08722,Q14203,Q9UQB8,O14786,P23396 19 +Hindlimb morphogenesis 0.6206325486311385 0.5022660094704166 0.6154804156380473 1.0 0.8774788485473529 3 O95747 1 +Embryonic hindlimb morphogenesis 0.6206325486311385 0.5022660094704166 0.6154804156380473 1.0 0.8774788485473529 3 O95747 1 +Macromolecule deacylation 0.3561421960564826 0.5022140749472672 0.6155169433013499 1.0 0.8774788485473529 41 Q9UMR5 1 +Organelle inheritance 0.4144429128912372 0.5004670540391789 0.6167462487947719 1.0 0.8788901266403834 10 P28482,P63104,Q02750,Q08379,P06493,P36507 6 +Positive regulation of intracellular protein transport 0.3483602060780862 0.4986060873770099 0.6180569158497564 1.0 0.8798709268285801 58 O75312,Q9NV96,Q9Y3D6,P55786,Q9H6U6,P27105,O00459,Q92688,Q15154,P49768,P08238,Q9C0E2,Q99828 13 +Golgi ribbon formation 0.4441378426748177 0.4982509788405708 0.6183071548898218 1.0 0.8798709268285801 7 O14744,Q08379,Q15643 3 +Protein peptidyl prolyl isomerization 0.3720647257048869 0.4980903639512987 0.6184203520575209 1.0 0.8798709268285801 27 O00170,O95302,Q13526 3 +Cell cell signaling 0.3997861457055004 0.4968745355620752 0.6192775296581332 1.0 0.8803993062656581 200 Q9UIQ6,O95219,O00560,Q13526,P67870,Q14118,Q12834,P05067,P50897,Q8NCG7,Q99538,P78310,Q4J6C6,P05556,Q07954,P22466,Q14517,P48960,P49768,Q9H2V7,Q13308,P19022,Q92542,Q13641,Q9Y4G8,Q06787,P51790,Q7L0J3,P78559,P43034,Q9UNF0,Q14168,Q9UQB8,O14786 34 +Regulation of cell aging 0.4037336776850638 0.4966793860003399 0.6194151613502532 1.0 0.8804046956270453 11 O75844 1 +Negative regulation of calcium ion transport 0.4332463301892771 0.4959238767268847 0.619948119568341 1.0 0.8804163839853211 8 P62942,Q06787 2 +Regulation of protein kinase activity 0.3410925558315997 0.4959088030166138 0.6199587550349661 1.0 0.8804163839853211 108 P54619,Q9P287,Q14118,P05067,Q9Y6N7,Q96A49,Q99828,P32780,P78536,P04792,O00410,O95373,P49768,P08238,Q96B36,O94992,Q12959,Q02750,Q9Y4G8,P07900,Q9Y376,Q13177,Q8ND04,P10644,Q8N122,P04062,Q53EL6,Q86Y37,P23396 29 +Organism emergence from protective structure 0.4698269025168635 0.4923224365811547 0.6224914214693777 1.0 0.8824889160399929 5 P49459 1 +Actin modification 0.6221033868092779 0.4890663812555315 0.6247947015992859 1.0 0.8846103200861176 2 Q86TU7 1 +Tissue regeneration 0.4414024216721519 0.4886989728302638 0.6250548311065267 1.0 0.8847094936768423 7 Q7Z4V5,Q14118 2 +Positive regulation of microtubule polymerization or depolymerization 0.3893728358115455 0.4868767247749204 0.626345694101826 1.0 0.885281902836659 14 Q15691,P63000,P36405,Q16512,Q14203,P23396 6 +Pigmentation 0.3820084163830383 0.4840328002284835 0.6283625911333535 1.0 0.8876392802690601 18 Q96AX1,O75787,P48444,Q9NP58,Q07812,Q13561,Q9Y4I1 7 +Xmp metabolic process 0.4397500743826368 0.482960891271211 0.6291235051931436 1.0 0.8876822001631297 7 P22102,O15067,Q06203,P31939,P30566,P22234 6 +Response to interleukin 4 0.4397500743826362 0.4829608912712085 0.6291235051931454 1.0 0.8876822001631297 7 P49327,P49736,P11802,P39023,P33993,P08238 6 +Intraciliary transport 0.4473810505865379 0.4826985780016059 0.6293097730715034 1.0 0.8877545973116768 6 Q9Y366,Q15154 2 +Regulation of mast cell activation 0.4393323083227874 0.4815139752981801 0.6301512495803778 1.0 0.8885605401371329 7 O95219 1 +Hemidesmosome assembly 0.6122779340694896 0.4794130692793558 0.6316447977290913 1.0 0.8895224747296002 3 P11047 1 +Regulation of oligodendrocyte differentiation 0.4284936024749 0.4785621236502683 0.6322501692182398 1.0 0.889746235337124 8 Q15382,Q14118 2 +Actin filament based process 0.3946530215534269 0.4785165091153278 0.6322826268344963 1.0 0.889746235337124 193 Q14126,Q9UJU6,O00560,Q9H6U6,P84095,P47756,P67936,P62993,P49006,P78310,P16949,Q9Y2I1,P05556,Q07954,Q9UM22,Q14517,Q9H0H5,Q04721,P06753,Q13308,O15143,P60983,O95429,Q02487,Q9NSV4,O94813,Q96JJ3,Q86VI3,Q13177,Q96PU5,Q14651,P11233,P10644,Q9Y624,P43034,P46108,Q9UNF0,Q08722,Q9UQB8,O14786 40 +Protein maturation by protein folding 0.4460720783804611 0.4783446816986727 0.6324048992305813 1.0 0.889746235337124 6 O00170 1 +Response to ischemia 0.3991929256546385 0.4777947791030953 0.6327962774743179 1.0 0.8899463281147246 11 Q96RD7,O95831,Q99828 3 +Pigment granule organization 0.4458655562165601 0.4776591651320772 0.6328928128489939 1.0 0.8899463281147246 6 O00203,O95295,O43747,Q9BXS5,Q9NP58 5 +Smooth muscle cell apoptotic process 0.4457680207897829 0.4773355470046801 0.6331232022633175 1.0 0.8900800223312894 6 P98175,Q53EL6 2 +Neurofilament cytoskeleton organization 0.6179441473559208 0.4770027149521741 0.6333601883586515 1.0 0.8902229314152157 2 P07196 1 +Mesenchymal to epithelial transition 0.5027973231832187 0.4753798060297116 0.6345162853559052 1.0 0.8908960779234033 4 P80723 1 +Positive regulation of translational initiation 0.3947123909410256 0.4734217854481288 0.6359122902660794 1.0 0.8926656093406468 12 Q7Z739,Q6PKG0,Q13144 3 +Regulation of neuron migration 0.4269767975882095 0.4730643951621096 0.6361672377439334 1.0 0.892832961356858 8 O94898 1 +Regulation of microtubule based process 0.3430007929238695 0.4724533968157653 0.6366031985744733 1.0 0.8930809162925256 64 Q9UQN3,Q9Y3E7,Q15691,Q9H444,P78318,Q16512,P16949,Q99828,Q66K74,P04350,P46821,Q8WUX9,Q8WUM4,Q02790,P63000,P11279,P63096,Q8TD16,P78559,P29372,P43034,P36405,Q14203,P23396 24 +Cellular anion homeostasis 0.6095096582466579 0.4719609812476485 0.6369546395710779 1.0 0.8930809162925256 3 O14745,P55011 2 +N terminal peptidyl methionine acetylation 0.6158645276292424 0.4710329753939777 0.6376171868765304 1.0 0.893723813184278 2 Q14CX7 1 +Positive regulation of protein containing complex assembly 0.3458079772138306 0.4702102001664272 0.6382048473386752 1.0 0.8943569420097582 55 Q15691,P17931,P62993,Q16512,P07737,P02786,Q07812,O95429,Q14247,Q12959,P63000,P07900,Q9UNE7,Q9NWS0,P35080,P36405,Q14203,Q9UQB8,P23396 19 +Intestinal epithelial cell differentiation 0.6143790849673293 0.4667945494150539 0.640646875876792 1.0 0.8951675374322449 2 P04818 1 +Intestinal epithelial cell development 0.6143790849673293 0.4667945494150539 0.640646875876792 1.0 0.8951675374322449 2 P04818 1 +Endosome to lysosome transport via multivesicular body sorting pathway 0.4991716705313144 0.4647979333398688 0.642076167900298 1.0 0.8951675374322449 4 Q9Y3E7 1 +Positive regulation of membrane protein ectodomain proteolysis 0.6067777482682071 0.4646668426414653 0.6421700565956265 1.0 0.8951675374322449 3 O43847 1 +Positive regulation of translation in response to endoplasmic reticulum stress 0.6065378900445777 0.4640293030194188 0.6426267514691251 1.0 0.8951675374322449 3 Q13217,Q04637 2 +Positive regulation of translation in response to stress 0.6065378900445777 0.4640293030194188 0.6426267514691251 1.0 0.8951675374322449 3 Q13217,Q04637 2 +Cytoplasmic sequestering of transcription factor 0.4606006541778262 0.4633433753637416 0.6431182595031371 1.0 0.8951675374322449 5 Q9UNN5,O75832,Q9UN86,O60826 4 +Platelet activation 0.3817388075615087 0.4628404943458952 0.6434787029845461 1.0 0.8951675374322449 16 Q9UPY5,P04792,Q13418,O00299,Q9Y624 5 +Regulation of muscle contraction 0.3749729492784369 0.461959527419936 0.6441103443798759 1.0 0.8951675374322449 20 Q02487 1 +Nucleotide excision repair dna gap filling 0.6056463595839539 0.4616637248527644 0.6443224885061181 1.0 0.8951675374322449 3 P28340,Q15054 2 +Response to hormone 0.3883911292219693 0.4614346305412327 0.6444868106155499 1.0 0.8951675374322449 184 Q06481,Q9H1E3,P26583,P67870,Q14118,Q9BSK2,Q99523,P42785,P22466,O75874,P16278,Q15043,O15118,O94813,Q13309,O00459,Q15392,O95831,P11166,P04062,P35613,Q9UQB8 22 +Negative regulation of smoothened signaling pathway 0.4408090422367729 0.4609974313492012 0.6448004479823557 1.0 0.8951675374322449 6 P63244,P17612,Q2M1P5,P06400,P55072 5 +Cellular carbohydrate biosynthetic process 0.3787105779513832 0.4563911991499541 0.6481086932703586 1.0 0.8951675374322449 17 O43505 1 +Positive regulation of transport 0.3916146465018015 0.4563365714556115 0.6481479693481484 1.0 0.8951675374322449 191 Q9NV96,Q06481,O95219,O00560,P50897,P05556,Q07954,P22466,P08183,Q92688,P19022,P11279,Q08431,O00459,Q96PU5,Q9C0E2,P27105,Q08722,P55786 19 +Fructose 1 6 bisphosphate metabolic process 0.43902439024391 0.4551740764121838 0.6489840089802912 1.0 0.8951675374322449 6 Q01813,Q9NQ88,P17858,P04075,P08237 5 +Gamete generation 0.3396654856114632 0.4549246796936047 0.6491634270294384 1.0 0.8951675374322449 111 Q96SB4,P54619,Q9BXW9,Q99598,P26583,Q9GZP4,P11717,P78310,Q99828,P05556,Q8NB78,P04920,Q9H0H5,Q6IBW4,Q9H2V7,Q9UJA3,Q9Y2W6,P07686,P41208,O75718,P43034,Q92692,Q8NB90,Q9H9C1,Q08J23 25 +Deadenylation dependent decapping of nuclear transcribed mrna 0.602828516572566 0.4542296167762151 0.6496635684050216 1.0 0.8951675374322449 3 Q86TB9 1 +Water soluble vitamin metabolic process 0.3728087035898433 0.453220801952448 0.650389754862166 1.0 0.8954089174305834 21 Q9NPF0,P33527 2 +Cellular monovalent inorganic anion homeostasis 0.6093285799168243 0.4525462000772846 0.6508755464021587 1.0 0.8955154453531479 2 P55011 1 +Maintenance of location in cell 0.3438794479198472 0.4516461402822882 0.6515239247181417 1.0 0.8962200704299322 48 Q13438,P02792,P10253,P49768,P62942,O43731 6 +Pons development 0.6017332390142729 0.4513576849056331 0.6517317758386025 1.0 0.896264957140271 3 O95487 1 +P body assembly 0.4020080363454634 0.4511661429170898 0.6518698094249085 1.0 0.896264957140271 10 Q86TB9,P62310,Q9HBH5 3 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.4937500824396165 0.449198007516601 0.6532888247039175 1.0 0.8975505505583969 4 Q96J02 1 +Sulfur compound metabolic process 0.3301990996838107 0.4474297356724045 0.6545648099088195 1.0 0.8990869324661128 100 P15586,O43505,Q9UMR5,Q9UJ14,P50897,P16278,Q9NX62 7 +Positive regulation of smooth muscle cell apoptotic process 0.4545956858945134 0.4449128886123689 0.6563827080524463 1.0 0.9000473301970923 5 P98175,Q53EL6 2 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.4190283045020208 0.4446114009286202 0.6566006069379053 1.0 0.9000473301970923 8 Q13309,Q13617 2 +Interleukin 10 production 0.4544820743837633 0.4445675810866416 0.6566322799659237 1.0 0.9000473301970923 5 P09429 1 +Regulation of alpha beta t cell differentiation 0.4543006876840977 0.4440165442000297 0.6570306226581293 1.0 0.900405715801078 5 P00491,P09429 2 +Nitric oxide synthase biosynthetic process 0.5984634001919645 0.4428433153291561 0.6578790704012643 1.0 0.9009436869024952 3 Q02952 1 +Positive regulation of nitric oxide synthase biosynthetic process 0.5984634001919642 0.4428433153291549 0.6578790704012651 1.0 0.9009436869024952 3 Q02952 1 +Nucleoside bisphosphate biosynthetic process 0.3607008613767228 0.4427161830584742 0.6579710355548172 1.0 0.9009436869024952 30 Q9UMR5 1 +Inner ear auditory receptor cell differentiation 0.4344148254395631 0.4402752954565891 0.6597377312235615 1.0 0.9026112304468776 6 Q14651,P43034,O95487 3 +Enteroendocrine cell differentiation 0.451943051129121 0.4368840221545093 0.662195459990444 1.0 0.9050325650980968 5 P19022 1 +Changes to dna methylation involved in embryo development 0.6033868092691717 0.4361109667803784 0.6627562207030242 1.0 0.9051788463987444 2 Q13263 1 +Organ growth 0.3676162297197726 0.4336373281321405 0.6645518236733177 1.0 0.9063840894377024 23 P07602,O75844 2 +Defense response to gram negative bacterium 0.4879738647783435 0.4328812591968953 0.6651010355924876 1.0 0.9069308897444824 4 P26583 1 +Growth hormone secretion 0.6019013666072583 0.4320585501331036 0.665698859443151 1.0 0.9074258825698154 2 Q06124 1 +Positive regulation of synaptic transmission gabaergic 0.6001188354129625 0.4272258330771051 0.6692148471885186 1.0 0.9108243497446048 2 P33176 1 +Regulation of synaptic transmission gabaergic 0.6001188354129625 0.4272258330771051 0.6692148471885186 1.0 0.9108243497446048 2 P33176 1 +Nucleotide transport 0.3755018639716348 0.4270526622257506 0.6693409709129552 1.0 0.9108243497446048 15 O00400,Q08722 2 +Positive regulation of neural precursor cell proliferation 0.4299028143928047 0.4258960136915019 0.6701836197678519 1.0 0.9117323724843984 6 P55209 1 +Cellular component assembly involved in morphogenesis 0.3677906073281018 0.4257562634643405 0.6702854596130359 1.0 0.9117323724843984 21 P05556,Q92692,P10644,Q14118 4 +Negative regulation of establishment of protein localization 0.362157452496579 0.4253698364121465 0.6705670912030008 1.0 0.911926881524362 26 Q13438,Q16850,Q9ULC3,Q9UMY4 4 +Regulation of jun kinase activity 0.4289216678921559 0.4227966109473815 0.6724436605368942 1.0 0.9131573903822646 6 Q53EL6 1 +Phosphatidylinositol 3 kinase signaling 0.3823302685543659 0.4211906359112116 0.6736158816321831 1.0 0.9143717023063352 12 Q05086,Q10713,O00459,P46934 4 +Regulation of reactive oxygen species biosynthetic process 0.4016284920939918 0.4164079663090066 0.6771115001035097 1.0 0.9175526073437148 9 P51790 1 +Positive regulation of autophagy 0.3550656988591891 0.4160763582705591 0.6773541291062752 1.0 0.9175526073437148 33 Q9H2M9,O95219,P09429,Q6UWE0,Q9Y6K9,Q6PKG0,Q13137 7 +Dephosphorylation of rna polymerase ii c terminal domain 0.5876564530949872 0.41535216624886 0.6778841179919588 1.0 0.9177528579627496 3 Q9NQG5 1 +Peptidyl proline modification 0.353245639328042 0.4153024425786765 0.6779205133537549 1.0 0.9177528579627496 35 Q9BV86,Q13526,O75718,O00170,O95302,Q32P28,P13674,P62942 8 +Positive regulation of chromosome condensation 0.4433541480820788 0.4113790437148238 0.6807946179064857 1.0 0.9208856665821228 5 Q9NTJ3,Q9BPX3,Q15021,Q15003 4 +Replication fork processing 0.3903366091458216 0.4063443807707196 0.6844895803833282 1.0 0.923225847808393 10 Q9H1E3 1 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.4780023781212746 0.4054806209642248 0.6851242603425542 1.0 0.923780838468846 4 P09874,Q15233,Q99497 3 +Protein localization to ciliary membrane 0.4412371119526045 0.4052110800813052 0.6853223611626587 1.0 0.923780838468846 5 Q9UPT5,Q15643 2 +Viral budding 0.3706594665779631 0.4046904106145448 0.6857050918227565 1.0 0.924107374310611 15 Q9UQN3,Q9Y3E7,Q9H444,Q6UWE0,Q8WUX9,Q8WUM4,P46934 7 +Regulation of trans synaptic signaling 0.3356862723128205 0.4021639033816979 0.6875634055861464 1.0 0.9260323171744824 63 P05556,P19022,Q92542,Q9Y4G8,Q06787,Q9UNF0,Q14168,P05067,P49768,Q99538,P78559,Q9UQB8,Q4J6C6 13 +Regulation of dna binding 0.3565389476463603 0.4017723316599953 0.6878515864129913 1.0 0.9260323171744824 27 O75844,P26583,P67870,P09429 4 +Histone threonine phosphorylation 0.4765265229584978 0.4015102221790224 0.6880445136427804 1.0 0.9260323171744824 4 Q9Y4B6 1 +Reactive oxygen species biosynthetic process 0.3797529340001832 0.3994118889302152 0.6895897352008591 1.0 0.9268739840930222 11 P51790 1 +Protein exit from endoplasmic reticulum 0.3622241298710633 0.3986971179222132 0.6901163917380435 1.0 0.9273923646277528 22 Q13438,Q9NV96 2 +Positive regulation of organic acid transport 0.4139019466837224 0.3966005132429426 0.6916620740206958 1.0 0.9282551179266156 7 P05556 1 +Nuclear membrane reassembly 0.3731007635068966 0.396295118526952 0.6918873279407414 1.0 0.9282551179266156 13 Q9UQN3,Q9Y3E7,Q9H6H4,Q9UNZ2,Q86XL3 5 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.3663681271969597 0.3955682225245334 0.6924235836420038 1.0 0.9285957865845262 17 O95831,Q9NR28,Q92688,Q9Y6N7 4 +Mitochondrial fragmentation involved in apoptotic process 0.4198336976200427 0.3945695914933984 0.6931605588583483 1.0 0.9293267537758374 6 Q9Y3D6,O00429,Q07812 3 +Mast cell activation 0.386891401500281 0.3934076300392939 0.6940184351028944 1.0 0.9297868159077064 10 O95219 1 +Regulation of leukocyte apoptotic process 0.3686963777368853 0.3930132795254713 0.6943096733217575 1.0 0.9299245582419732 14 Q9UPY5,P78536,P17931,Q9Y4G8,P42771,Q07812 6 +T cell activation involved in immune response 0.4040921908530607 0.3928855866447385 0.6944039875470618 1.0 0.9299245582419732 8 P49768,P09429 2 +Respiratory system development 0.3526340868921288 0.3893399464964111 0.6970246898255239 1.0 0.931953904689524 28 P28482,P63104,Q15185,Q02750,Q14118,P80723,P38571,Q13308,O60476,P09960 10 +Response to cytokine 0.3653272634721367 0.3888764540386185 0.6973675408961957 1.0 0.9319958724126728 156 Q06481,P78318,P67870,P05067,Q9Y6N7,P02786,P78536,Q8TCT8,O95429,Q13510,O94813,P63241,P67809,Q9Y3Z3,P04062,P43034,Q08722,Q13137,P23396 19 +Negative regulation of dephosphorylation 0.3660507188221583 0.387843081080109 0.6981321619855267 1.0 0.9324734586080872 16 O95429,P62258,O75116,P17931,Q9UHD1,Q96GX5,P46940,P62942,Q12972 9 +Early endosome to golgi transport 0.4107932798024751 0.3866811246682007 0.698992291569398 1.0 0.9326366483139918 7 O15260,O60749 2 +Cation transport 0.3718100638844409 0.3858310227174037 0.6996218181193883 1.0 0.9326366483139918 167 O95219,P30825,Q13423,Q9BXP2,P05067,O00400,P02786,P05556,P22466,O43772,Q15043,P02792,P51790,P06756,P27105,Q96QD8,O75844,Q9H2J7,P08195 19 +Cytoplasmic pattern recognition receptor signaling pathway 0.3642348377629051 0.3852422388554478 0.7000579516881895 1.0 0.9326366483139918 17 O75179,O43657 2 +Positive regulation of cellular component organization 0.4147333988963214 0.3851645560151593 0.7001155015771499 1.0 0.9326366483139918 266 Q9NV96,P23396,Q06481,O95219,Q9UJU6,O00560,Q12834,Q14118,P62993,P05067,P48681,P50897,Q9Y6N7,P02786,Q9H4M9,Q14108,Q07954,P49768,Q13308,O15260,O95429,Q9HBH5,O94813,Q13641,Q9Y4G8,Q06787,P63241,Q32P28,Q96PU5,Q08722,Q9NUM4,P11233,Q9P2S5,P04062,Q14444,Q9P273,P43034,P29317,Q14203,Q9UQB8,Q13137,O14786 42 +Positive regulation of telomere capping 0.4699762187871448 0.3841614119704927 0.7008588167894956 1.0 0.9334378005347846 4 P28482,P27361,Q14103 3 +Positive regulation of behavior 0.5736139689853834 0.3811819405342363 0.7030682487258912 1.0 0.9350551840111024 3 Q96QK1 1 +Protein localization to microtubule organizing center 0.3688517003463891 0.3783619587134502 0.7051617238738079 1.0 0.936703113821064 13 Q9P2S5,Q15691,Q8IVD9,Q15154,Q13561 5 +Positive regulation of muscle hypertrophy 0.3985119047619068 0.374190804817322 0.7082623646079027 1.0 0.93941400614933 8 P09874,Q9UGN5,Q13464,P58546,Q12792,O75116,P17252 7 +Melanocyte differentiation 0.5796197266785597 0.3740951125658251 0.7083335547602301 1.0 0.93941400614933 2 Q86YV9 1 +Nadp metabolic process 0.3643453287070823 0.3739175213926507 0.7084656802845286 1.0 0.93941400614933 14 Q13423 1 +Positive regulation of protein deubiquitination 0.5694395676156211 0.3713758224849577 0.7103576308899988 1.0 0.9400236293497998 3 Q9NZM5 1 +Establishment of spindle orientation 0.3709389495436316 0.3653477907619764 0.7148518083977491 1.0 0.9438569240546756 11 P05556,P43034 2 +Outer ear morphogenesis 0.5664677994135409 0.3644956424011965 0.7154879271959698 1.0 0.94409008563391 3 P28482 1 +Ketone catabolic process 0.5754604872252036 0.3638827822662791 0.7159455423187693 1.0 0.9441671231543128 2 Q99497 1 +Dna strand elongation involved in dna replication 0.3618795653778818 0.363208301770771 0.7164492865737095 1.0 0.9442818277876402 14 P49005 1 +Ion transport 0.3984765459257984 0.3632039862435137 0.7164525100771872 1.0 0.9442818277876402 224 Q6PCB8,O95219,P30825,Q13423,Q9BXP2,P05067,O00400,Q8NE01,P02786,P07602,P62942,Q9C0H2,P05556,P51798,P22466,P08183,Q9HC07,O43772,P49768,Q9UHG3,Q15043,P33527,P02792,Q06787,P13693,P51790,Q7L0J3,Q96PU5,P06756,P11166,P27105,Q96QD8,O75844,Q08722,Q9H2J7,P08195 36 +Regulation of dna binding transcription factor activity 0.3287426183452696 0.3613221050974172 0.7178586708692756 1.0 0.9454273726664302 68 Q12899,Q9BXW9,Q86VP1,Q9Y6K9,P05067,P02786,P23396 7 +Maintenance of protein localization in organelle 0.3601511861361393 0.3604317251579516 0.718524305431512 1.0 0.9458580910803456 16 O43731 1 +Meiotic spindle assembly 0.5634960312114606 0.3577003115246957 0.7205675999461465 1.0 0.9475996946113058 3 Q08379 1 +Multivesicular body organization 0.3583171837808717 0.3569133289352197 0.7211566909447376 1.0 0.9478059366702264 17 Q9UQN3,Q9Y3E7,Q9H444,Q99816,Q8WUX9,Q8WUM4,P53990,O14964,Q9BRG1 9 +Clathrin coat assembly 0.39305687135218 0.3562701201060996 0.7216382838912527 1.0 0.9478707331143492 8 P42566 1 +Female meiosis chromosome segregation 0.4588516792956471 0.3557503606829383 0.7220275265881866 1.0 0.9479901728566026 4 Q6IBW4 1 +Regulation of respiratory burst 0.5617549614806717 0.3537588900798061 0.7235195846898408 1.0 0.9479901728566026 3 P11274 1 +Embryo development ending in birth or egg hatching 0.3494128459681157 0.3533106230915002 0.7238555823643769 1.0 0.9479901728566026 137 P42892,Q6GQQ9,P62993,P61201,P05556,Q9BRT9,Q14574,P49459,O43772,Q04721,P49768,Q13308,P49321,Q02487,Q8TCT9,P67809,O95747,Q15648,P11233,O75312,O43678,P29317,Q08J23 23 +Positive regulation of canonical wnt signaling pathway 0.3585220500329323 0.3529459823272372 0.724128937415798 1.0 0.9479901728566026 16 Q13418,Q13526,O75787,Q96K76,Q13308 5 +Regulation of reactive oxygen species metabolic process 0.3466987662747312 0.3528789721235096 0.7241791758291924 1.0 0.9479901728566026 30 P42785 1 +Negative regulation of regulated secretory pathway 0.4224044847242311 0.3525304443225528 0.7244404907668351 1.0 0.9481435631246004 5 Q06787 1 +Response to angiotensin 0.4572144119269539 0.3516840997954606 0.7250751862785765 1.0 0.9484081478107924 4 Q04206,O43865 2 +Vacuolar localization 0.353479401217653 0.3483238223810511 0.7275970050666769 1.0 0.9497199781925711 20 Q9NUM4 1 +Cellular response to reactive oxygen species 0.345989282215312 0.3482315906486707 0.7276662648359014 1.0 0.9497199781925711 28 Q99720,O95831 2 +Positive regulation of osteoblast differentiation 0.4202775680774155 0.3468385846513379 0.7287125879870238 1.0 0.9505198103864054 5 O00299 1 +Epiboly 0.4034260586768706 0.345942883807417 0.7293856394705218 1.0 0.9510205622273722 6 O14656,Q7Z460,P78536 3 +Response to corticosterone 0.5671420083184897 0.3440545111403934 0.7308052916552372 1.0 0.9524618334237916 2 P07196 1 +L glutamate transmembrane transport 0.3808927773756131 0.3432401426139764 0.7314178075416331 1.0 0.9525373862619012 9 P05556 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.3540148166082778 0.3428916026143931 0.731680009370516 1.0 0.9526902418129958 18 P78536,Q9H223,O14786 3 +Regulation of stress granule assembly 0.5556494756298873 0.3401721805133708 0.7337268670002308 1.0 0.95441078329593 3 Q13283 1 +Negative regulation of calcium ion transmembrane transport 0.3944153749569675 0.3362664482382494 0.736669948672676 1.0 0.9556999294636028 7 P62942 1 +Regulation of mrna export from nucleus 0.4000026822368976 0.336199443745152 0.7367204723471807 1.0 0.9556999294636028 6 Q96ST2 1 +Interleukin 8 production 0.3628072651501538 0.3348353486170263 0.7377492937891368 1.0 0.9556999294636028 11 P09429 1 +Tetrapyrrole metabolic process 0.3503846422255167 0.3345376808150285 0.7379738619378395 1.0 0.9556999294636028 22 Q9NPF0 1 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.354919268312953 0.3334400158498612 0.7388021614104978 1.0 0.9556999294636028 14 Q9UQN3,Q9Y3E7,Q9H444,Q8WUX9,P46934,Q9BRG1 6 +Macrophage migration 0.398826067270451 0.3328840144199227 0.7392218365933128 1.0 0.9556999294636028 6 P28482,P17931,P30046 3 +Macrophage chemotaxis 0.398826067270451 0.3328840144199227 0.7392218365933128 1.0 0.9556999294636028 6 P28482,P17931,P30046 3 +5 phosphoribose 1 diphosphate metabolic process 0.4493976030813749 0.3326896756679041 0.7393685436643411 1.0 0.9557017646343164 4 Q14558,P06737 2 +Regulation of dna templated transcription initiation 0.3544762482535216 0.3315691592003352 0.7402146107175751 1.0 0.9564137940223422 14 Q9NPJ6,Q6VMQ6,P09429,P53999,Q15648 5 +Dephosphorylation 0.3144583880825269 0.3308691374921729 0.7407433349061763 1.0 0.9564355494398106 94 P78318,P17931,Q13526,P67870,Q8NCE2,P62942,Q9ULE6,Q9H0C8,Q86XL3,O15355,P08238,P63151,Q6IN85,Q9NX62,P11117,P34913,Q8WVY7,O95429,Q12959,P10586,Q9H0R4,Q10713,Q9H993,P04062 24 +Neuron death in response to hydrogen peroxide 0.5609031491384543 0.3297147254462984 0.7416155261010426 1.0 0.9564355494398106 2 Q99497 1 +Response to interleukin 3 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.958638498135088 2 P49840 1 +Regulation of glycogen starch synthase activity 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.958638498135088 2 P49840 1 +Negative regulation of glycogen metabolic process 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.958638498135088 2 P49840 1 +Negative regulation of cell cell adhesion 0.3502644066684743 0.3247625888816693 0.7453607607749309 1.0 0.958638498135088 18 P17931,Q96J02,P10644,P09429 4 +Pentose phosphate shunt 0.3830357142857162 0.3243099924911544 0.7457033552625447 1.0 0.958638498135088 8 P11413,O95336,P52209,P37837,Q9NQ88,P18669,P29401 7 +Regulation of cell differentiation 0.3969240786961794 0.3233430476088563 0.7464354561289546 1.0 0.959181955541368 229 O15347,O60271,Q96PZ0,Q06481,P19525,P01130,Q9BXW9,Q9UJU6,P17931,O00560,P26583,Q14118,A0MZ66,Q9GZP4,P05067,Q9Y6N7,P55209,Q96A49,P05556,Q99523,O75179,Q9UIW2,Q92688,Q04721,P49768,P08238,Q6YHK3,O94813,Q8N0X7,Q9Y4G8,Q92896,P67809,O95747,P06730,Q15648,Q96J02,P06756,Q9BYT8,P01889,P09429,Q53EL6,Q14444,Q9Y624,P43034,P46108,Q15375,Q15154,Q15382,Q9UQB8,Q08J23,O14786 51 +Positive regulation of kinase activity 0.3218954990812173 0.3205830504141467 0.7485263839975274 1.0 0.960180685244878 72 P54619,Q14118,Q9Y6N7,Q96A49,Q99828,P78536,P49768,P08238,Q12959,Q02750,Q9Y4G8,P07900,Q9Y376,Q13177,Q8N122,Q15375,Q86Y37,P29317,Q969S3,P23396 20 +Positive regulation of cytokine production 0.3256315696205483 0.3194258018326713 0.7494036477885098 1.0 0.9609312271253054 65 P78536,P09429,P26583,O60684,P05067,P49768,P04439,Q9BUI4,Q13283,P23396 10 +Regulation of phosphoprotein phosphatase activity 0.3497007308309693 0.3165524136824796 0.7515832484460767 1.0 0.9627876549714298 17 P08238,P62942,P67870 3 +Cation transmembrane transport 0.3394819381899521 0.3152963405273197 0.7525366632517967 1.0 0.9632586438743566 128 P30825,Q13423,Q9BXP2,P05067,O00400,P62942,P05556,P22466,Q9HC07,O43772,P49768,Q15043,Q06787,P51790,Q9Y376,Q96PU5,P06756,P27105,Q9Y619,Q9H2J7,P08195 21 +Mammalian oogenesis stage 0.5540701128936536 0.3145416172516509 0.753109713155049 1.0 0.9635180124628316 2 P62753 1 +Purine deoxyribonucleoside monophosphate metabolic process 0.5434187415317406 0.3140762840703711 0.7534631013831368 1.0 0.9635180124628316 3 P00491 1 +Damp metabolic process 0.5434187415317406 0.3140762840703711 0.7534631013831368 1.0 0.9635180124628316 3 P00491 1 +Biomineralization 0.355387408276554 0.3140649997935925 0.753471671649256 1.0 0.9635180124628316 12 P04920,Q6P4Q7,O95747,O75844 4 +Cardiac muscle cell proliferation 0.5430279885191505 0.3132676488597652 0.7540773264828813 1.0 0.9637304553340572 3 P10644 1 +Positive regulation of cell matrix adhesion 0.3499841685037635 0.3127673989914685 0.7544573854293577 1.0 0.964028881381957 14 O14786 1 +Calcium mediated signaling using intracellular calcium source 0.4405469678953546 0.3120393518273053 0.7550106169212678 1.0 0.9643611336132232 4 P51572,Q9Y3D6,P17612 3 +Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway 0.5525846702317404 0.3113175863128937 0.7555591991628647 1.0 0.964584051888044 2 Q99497 1 +Anterograde axonal transport 0.3492901596500458 0.3098904121269452 0.7566442941663658 1.0 0.9647498552940954 14 P78559,Q14168 2 +Abscission 0.5413692190074374 0.3098524462454942 0.756673166574287 1.0 0.9647498552940954 3 Q8N0X7 1 +Regulation of phosphatase activity 0.3457616789559298 0.3090347927293728 0.7572950605479072 1.0 0.96510015598549 20 P08238,P62942,O95429,P67870 4 +Protein refolding 0.353832518969248 0.3081942719524297 0.7579345108013482 1.0 0.965471187461516 12 P48723 1 +Muscle structure development 0.3164318814814507 0.3077974992086559 0.7582364246150695 1.0 0.965481843034829 99 P05556,Q99523,P19022,O60271,Q53EL6,O75179,Q8IV08,Q7Z4V5,Q14118,P67809,O75844,P62942,P78310,P10644,Q9H4M9 15 +Negative regulation of ubiquitin protein ligase activity 0.3773316709777514 0.3067015680369315 0.7590705361514583 1.0 0.9663568776474342 8 P62829,P60866,P62913 3 +Tissue development 0.4137614722964071 0.3061178598690685 0.7595149100506977 1.0 0.9664913290493328 291 Q14126,P42892,Q96PZ0,O14773,Q9P287,O00560,P67870,Q14118,P62993,Q9Y6N7,P07602,P78310,P62942,P05556,Q15643,P78536,P22466,Q14517,P10253,P49768,Q13308,Q15043,Q9NX62,Q6YHK3,P19022,Q13510,O94813,Q8N0X7,Q9Y4G8,Q92896,Q86VI3,P11047,P67809,P13693,Q15392,P11233,P10644,P06756,P09960,Q53EL6,P07942,P04080,O43598,Q9Y624,P43034,P07437,P35613,Q15375,O75844,P29317,Q08J23,O14786 52 +Ribonucleoprotein complex localization 0.3839683953936543 0.3058368021595052 0.7597289061101726 1.0 0.9664913290493328 7 Q96ST2 1 +Somatic diversification of immune receptors via somatic mutation 0.3830167642593926 0.3031356046739792 0.7617865212958732 1.0 0.9686896843387308 7 Q9Y3Z3,P13051 2 +Histone h4 acetylation 0.3423270723039483 0.3019812748295538 0.7626663374989087 1.0 0.9689605653546036 25 Q86UY6,O75844 2 +Regulation of phosphatidylinositol 3 kinase signaling 0.3684331924357911 0.3018898143201756 0.7627360607184763 1.0 0.9689605653546036 9 Q05086,Q10713,P46934 3 +Cellular pigmentation 0.3532983189459548 0.3003574453283645 0.7639045196601664 1.0 0.969605580944906 11 Q13561,Q9NP58,Q96AX1,Q9Y4I1 4 +Cellular response to oxygen levels 0.3362717034099997 0.2996401022874649 0.7644516916413804 1.0 0.969605580944906 35 Q15904,P55786 2 +Membrane disassembly 0.3864059399327363 0.2989608668025962 0.7649699045190328 1.0 0.969605580944906 6 P43034 1 +Pyrimidine containing compound metabolic process 0.3406321894668894 0.2984944223066309 0.7653258325569678 1.0 0.969605580944906 26 Q9H773,P13051 2 +Peptidyl proline hydroxylation 0.3810972135553568 0.2977237797419364 0.7659139924119716 1.0 0.969605580944906 7 Q32P28,P13674 2 +Dna replication independent chromatin organization 0.3809930528097885 0.2974315325240406 0.7661370728676304 1.0 0.969605580944906 7 Q8TEX9,O14929,P49321 3 +Positive regulation of microtubule nucleation 0.400758567432157 0.2972119810510564 0.7663046753900358 1.0 0.969605580944906 5 Q14203 1 +Dna damage induced protein phosphorylation 0.5454545454545571 0.2962162985867633 0.7670649026121812 1.0 0.9702727204443024 2 P27361 1 +Cellular response to organic cyclic compound 0.3287620433303372 0.2960897900589926 0.767161510950261 1.0 0.9702727204443024 116 Q92542,O15118,Q13309,Q9Y4G8,Q5KU26,P05067 6 +Localization within membrane 0.3804171675721517 0.2945702046921405 0.7683222259200742 1.0 0.9709939677429872 198 Q9Y3D6,Q07960,O95219,P17931,O00560,P84095,Q14118,Q8TAG9,P07602,Q9HD20,Q9H223,Q9H4M9,Q99828,Q4J6C6,P05556,Q9HD45,Q15643,Q07954,Q9UEU0,Q9H173,Q13356,Q07812,P09132,P19022,O95429,O15400,Q12959,Q9NS69,O15118,O75955,Q13641,P07900,Q9Y4G8,Q15904,Q14651,Q9UBQ0,P42566,P11233,Q9UPT5,Q9H2M9,Q9UMY4,Q9Y624,Q8N3F8,P27105,P35613,Q96L92,P29317,Q14168,O60725 49 +Postsynaptic modulation of chemical synaptic transmission 0.3981564079690827 0.2909637981226417 0.7710790070995124 1.0 0.9719992271448384 5 Q7L576,P06730,P40818,P38919 4 +Trachea development 0.4306354620789014 0.290026227240782 0.7717961730750573 1.0 0.9719992271448384 4 Q02750,P28482 2 +Trachea morphogenesis 0.4306354620789014 0.290026227240782 0.7717961730750573 1.0 0.9719992271448384 4 Q02750,P28482 2 +Trachea formation 0.4306354620789014 0.290026227240782 0.7717961730750573 1.0 0.9719992271448384 4 Q02750,P28482 2 +Lactate metabolic process 0.3828078524687668 0.289510579932778 0.7721906847734272 1.0 0.9719992271448384 6 P07195,O75746,P00338,Q9NQ88,Q99497 5 +Macromolecule catabolic process 0.4032735931002004 0.2889167543413468 0.7726450821165511 1.0 0.9721613141091572 445 Q9Y3E7,O14773,Q9UIQ6,Q96KB5,O94898,P01130,P15586,O00584,O75503,Q6GQQ9,P28074,O00560,Q13526,Q9NYU1,Q9GZP4,P50897,Q99538,Q8TEY7,P04066,Q07954,O14967,Q13438,P54802,P60520,P13473,P10619,P10253,P49459,Q92530,P16278,P60900,P49721,P49768,P53634,Q9UHG3,Q9HBH5,P28070,Q13309,Q9BW61,Q9H814,Q86TB9,Q06787,P67809,P28072,O00115,Q96PU5,Q8ND04,P78559,Q9NUM4,O95831,Q7Z739,O75312,P04062,Q9UMY4,P62913,Q16850,O75844,Q86Y37,Q08J23,O43847 60 +Process utilizing autophagic mechanism 0.3691913720519934 0.2882308758286621 0.7731700156873851 1.0 0.9724663161599244 178 Q9UQN3,Q9Y3D6,Q9Y3E7,O95219,O15269,Q9Y6K9,Q8NCE2,P07602,Q8TEY7,Q66K74,P04792,Q9UEU0,P60520,Q93050,P13473,P10619,P49768,Q14247,O15118,P07900,P06730,O00459,Q9UBQ0,Q9UPT5,Q9Y3C8,Q8N122,Q9H2M9,P04062,P09429,Q6UWE0,Q9ULC3,Q9H9C1,Q15382,O75844,Q6PKG0,Q86Y82,Q13137,Q9H6U6 38 +Muscle cell development 0.3362402499990827 0.2880205644187713 0.7733309972381521 1.0 0.9724663161599244 31 P05556,P78310,O75844 3 +Vesicle uncoating 0.4295481569559933 0.2876843378819613 0.7735883799879197 1.0 0.9726040450230382 4 Q99961,P11142,O14976 3 +Neutrophil activation involved in immune response 0.4291083477299281 0.2867411972770418 0.7743104906522016 1.0 0.9726108216631588 4 Q15833,P11274 2 +Neutrophil degranulation 0.4291083477299281 0.2867411972770418 0.7743104906522016 1.0 0.9726108216631588 4 Q15833,P11274 2 +Organelle transport along microtubule 0.3360337513489042 0.286728122436472 0.7743205027093458 1.0 0.9726108216631588 31 P11279,Q8TD16,Q9Y678 3 +Regulation of microtubule cytoskeleton organization 0.323963669313853 0.2864090705866624 0.7745648282432329 1.0 0.9726108216631588 51 Q9H444,Q9UQN3,Q9Y3E7,Q15691,Q16512,P16949,Q99828,Q66K74,P04350,P46821,Q8WUX9,Q8WUM4,Q02790,P63000,P63096,Q8TD16,P78559,P29372,P43034,P36405,Q14203,P23396 22 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.370543730011909 0.2863255681694798 0.7746287769372588 1.0 0.9726108216631588 8 P13693,P23396 2 +Dna dependent dna replication maintenance of fidelity 0.3429746441309306 0.2840648059768176 0.7763607171912672 1.0 0.9737084573911484 14 Q9H1E3 1 +Neutrophil homeostasis 0.5282459042498104 0.2838429422788081 0.7765307441430762 1.0 0.9737084573911484 3 P09429 1 +Axonal transport 0.3408453297941573 0.2838319663683928 0.7765391558944914 1.0 0.9737084573911484 21 P78559,Q14168,P43034,Q14203 4 +Imp metabolic process 0.3484199103892385 0.2832038252102636 0.7770205962488506 1.0 0.9738212148389284 11 P00492,P07741 2 +Positive regulation of cellular respiration 0.4271700356718129 0.2826131265338834 0.7774734168688255 1.0 0.9740343542086456 4 Q9Y255,Q99497,P55072 3 +Negative regulation of hemopoiesis 0.3692539676296194 0.2825270168512022 0.7775394335587713 1.0 0.9740343542086456 8 P09429 1 +Anatomical structure formation involved in morphogenesis 0.3633918103594322 0.281896101713011 0.7780231787558041 1.0 0.9743483523625884 169 Q14118,Q9Y6N7,P62942,Q9H4M9,P05556,Q13685,P78536,P42785,P49768,Q6YHK3,Q08431,O94813,P10644,P43121,P06756,P04062,P07942,Q92692,P35613,P29317,O14786 21 +Response to human chorionic gonadotropin 0.5380273321449911 0.2811501261978333 0.7785952558557137 1.0 0.9746145752652492 2 P48506 1 +Ion transmembrane transport 0.3632828917406617 0.280723150274442 0.7789227511116059 1.0 0.9747805107330958 169 Q6PCB8,P30825,Q13423,Q9BXP2,P05067,O00400,Q9C0H2,P05556,P22466,P08183,O43772,Q9UHG3,Q15043,P33527,P51790,P06756,P27105,O75844,Q9H2J7,P08195 20 +Positive regulation of synaptic plasticity 0.5259197812107067 0.2794219152076105 0.7799210546875666 1.0 0.9749180892676024 3 Q12834 1 +Plasma membrane repair 0.3681873111764102 0.2794034817958949 0.7799351993563879 1.0 0.9749180892676024 8 Q9UQN3,Q9Y3E7,Q9H444,P35579 4 +Positive regulation of release of cytochrome c from mitochondria 0.3788018335291311 0.2791945228453839 0.7800955467229536 1.0 0.9749180892676024 6 O14737,Q07812 2 +Microtubule nucleation 0.3415289116858639 0.2782453173244211 0.7808240495868031 1.0 0.9749180892676024 14 Q96P70,Q08379,Q16512,P23258,Q7Z460,Q96CW5,Q14203 7 +Defense response to other organism 0.3581750363247544 0.2779884580578209 0.7810212188329371 1.0 0.9749180892676024 161 O15347,Q96SB4,Q9Y3E7,Q06481,P19525,O00584,P26583,Q5KU26,Q9Y6K9,Q9BUI4,Q13283,Q12899,P78536,O75179,Q9NUQ8,Q04721,P08238,O94992,P11279,Q13309,Q9Y3Z3,Q13177,P04439,Q15648,Q08722,Q96J02,Q7Z739,P01889,P09429,O43657,Q6UWE0,Q92692,P07437,P46108,O75844,P29317,P10321,Q13137 38 +Cysteine metabolic process 0.4247919143876234 0.2776121100679044 0.7813101349412932 1.0 0.9749180892676024 4 Q9UPY5,P48507,P48506 3 +Negative regulation of type i interferon mediated signaling pathway 0.4239959266153642 0.2759539540329682 0.7825834328087438 1.0 0.9749180892676024 4 Q9Y3Z3 1 +Negative regulation of mrna 3 end processing 0.3916146297948317 0.2756521141285287 0.7828152784349971 1.0 0.9749180892676024 5 O00267,O75150,Q5VTR2,Q6PD62 4 +Embryonic pattern specification 0.3728057538988961 0.2749239659081362 0.7833746542250217 1.0 0.9749180892676024 7 Q9Y2W6,O14786 2 +Translational elongation 0.3352741522035879 0.2747879945553476 0.783479122137225 1.0 0.9749180892676024 27 P24534,Q7Z2Z2,Q9H2P9,O00178,P63241,P29692,P26641,P49588,Q9H1I8,O60524,P05387,Q15650 12 +Macroautophagy 0.3290030797319075 0.2744036508233791 0.7837744377021667 1.0 0.9749180892676024 119 Q9UQN3,Q9Y3E7,O95219,O15269,Q9Y6K9,Q9UEU0,P60520,Q93050,P13473,P49768,O15118,Q9H2M9,P04062,Q6UWE0,Q9ULC3,Q9H9C1,Q15382,Q6PKG0,Q86Y82,Q13137 20 +Cellular response to virus 0.3388922376788564 0.2742416517072123 0.783898921188511 1.0 0.9749180892676024 22 O75179,O43657,Q06787,P63241,Q07812 5 +Cellular protein catabolic process 0.4024566139706207 0.270884547650714 0.7864798300412057 1.0 0.9758998107290612 258 Q9Y3E7,O14773,Q96KB5,P01130,Q6GQQ9,P28074,O00560,Q9NYU1,Q12834,Q9GZP4,P50897,Q99538,Q8TEY7,Q07954,O14967,Q13438,P61088,P60520,P13473,Q96K76,P49459,Q92530,P60900,P49721,P49768,P53634,O60524,Q9UHG3,P08238,Q04323,P28070,Q13309,Q9BW61,Q8TCT9,Q99436,Q06787,P28072,Q96PU5,P78559,Q96J02,Q9NUM4,P04062,P62913,O75844,Q86Y37 45 +Positive regulation of nitric oxide metabolic process 0.421530177555491 0.270867790582208 0.7864927186240347 1.0 0.9758998107290612 4 P08238 1 +Protein demannosylation 0.3891967575921672 0.2701381349492384 0.7870539848716089 1.0 0.9758998107290612 5 O60476 1 +Cardiac ventricle morphogenesis 0.3890710848729923 0.2698537012771732 0.7872728071386084 1.0 0.9758998107290612 5 P62942 1 +Positive regulation of exosomal secretion 0.3708963610486446 0.269808838853745 0.7873073225088745 1.0 0.9758998107290612 7 O00560,Q8WUM4,O14964 3 +Negative regulation of inclusion body assembly 0.5203566121842513 0.2690823760059442 0.7878662923400224 1.0 0.9763723570106758 3 P0DMV9,P54652 2 +Smooth muscle cell differentiation 0.3702879129962427 0.2681896767395114 0.7885533207985129 1.0 0.976487903654484 7 Q53EL6 1 +Reticulophagy 0.4194411414982105 0.2666184699105059 0.7897629333314387 1.0 0.9772328990738474 4 Q9Y3C8,Q9GZZ9,Q96HY6 3 +Protein polyufmylation 0.4194411414982104 0.2666184699105059 0.7897629333314387 1.0 0.9772328990738474 4 Q9Y3C8,Q9GZZ9,Q96HY6 3 +Deoxyribonucleoside triphosphate biosynthetic process 0.5188707280832111 0.2663768029240405 0.7899490286186701 1.0 0.9772328990738474 3 P04818,P23919 2 +Stress granule disassembly 0.5185735512630031 0.2658385326956047 0.7903635658148858 1.0 0.9774415371179392 3 Q07866,P33176 2 +Negative regulation of protein polyubiquitination 0.41825208085611 0.2642243816647565 0.7916070246140294 1.0 0.9776186671320148 4 O95071,Q9Y263,Q96FW1 3 +Negative regulation of protein k63 linked ubiquitination 0.41825208085611 0.2642243816647565 0.7916070246140294 1.0 0.9776186671320148 4 O95071,Q9Y263,Q96FW1 3 +Negative regulation of intracellular signal transduction 0.3201764285849538 0.2623061461144942 0.7930854239671548 1.0 0.9787834744570252 109 Q96KB5,Q6GQQ9,P78318,Q13526,Q14118,P16949,P05556,P04792,Q96K76,Q96B36,O94813,P13693,Q10713,O00459,Q96J02,P04062,Q53EL6,O43657,P43034,P29317 20 +Protein localization to mitochondrion 0.3207887511407963 0.2617896820134365 0.7934835942914664 1.0 0.9789917597689978 59 O95429,Q99595,O60830,O00170,Q10713,Q8N4H5,P55786,O95831 8 +Regulation of synaptic vesicle recycling 0.3718024985127849 0.2617011562234186 0.793551849055685 1.0 0.9789917597689978 6 Q00535,Q9Y263,Q13464,O14656,Q7L576 5 +Positive regulation of podosome assembly 0.5156017830609229 0.2605080734637117 0.7944718885271795 1.0 0.979575648122172 3 Q9BPX3,P26038 2 +Regulation of podosome assembly 0.5156017830609229 0.2605080734637117 0.7944718885271795 1.0 0.979575648122172 3 Q9BPX3,P26038 2 +Positive regulation of leukocyte apoptotic process 0.3671733083109884 0.2599839460096079 0.7948761571365299 1.0 0.9797164239815483 7 P42771,Q9Y4G8,Q07812 3 +Response to acetylcholine 0.3841807909604597 0.25895280931745 0.7956716514853941 1.0 0.9801307647197196 5 P04899,P46109,O75116,P29992 4 +Ump biosynthetic process 0.3839506706761265 0.2584479242160712 0.7960612343461606 1.0 0.9801307647197196 5 Q9BZX2 1 +Pyrimidine ribonucleoside monophosphate metabolic process 0.3839506706761265 0.2584479242160712 0.7960612343461606 1.0 0.9801307647197196 5 Q9BZX2 1 +Development of primary female sexual characteristics 0.339567290422184 0.2561292820676782 0.7978510121120233 1.0 0.9810212310496704 12 Q13144,O75874,O94813,Q05086,Q07812 5 +Amino sugar biosynthetic process 0.5129271916790507 0.2557920454885009 0.7981114164089997 1.0 0.9810212310496704 3 Q06210,O95394 2 +Udp n acetylglucosamine biosynthetic process 0.5129271916790507 0.2557920454885009 0.7981114164089997 1.0 0.9810212310496704 3 Q06210,O95394 2 +Positive regulation of mitochondrial depolarization 0.5246583481877722 0.2557595879314477 0.7981364803778825 1.0 0.9810212310496704 2 P63244 1 +Striated muscle cell apoptotic process 0.3826940231935876 0.2557037058714249 0.7981796334110423 1.0 0.9810212310496704 5 P17655,Q9NQ88,Q96QC0,O95817 4 +Regulation of hyaluronan biosynthetic process 0.5237670825906235 0.2541463904298962 0.7993824652359862 1.0 0.981582575382176 2 Q00610 1 +Hyaluronan biosynthetic process 0.5237670825906235 0.2541463904298962 0.7993824652359862 1.0 0.981582575382176 2 Q00610 1 +Hyaluronan metabolic process 0.5237670825906235 0.2541463904298962 0.7993824652359862 1.0 0.981582575382176 2 Q00610 1 +Protein import into peroxisome membrane 0.4120095124851318 0.2519497710285249 0.80107988843593 1.0 0.9826006256426936 4 Q9Y5Y5,P56589,P40855 3 +Homologous recombination 0.3522217605238275 0.2513972424633463 0.8015069994613728 1.0 0.9826006256426936 9 Q9H1E3 1 +Positive regulation of mitotic cell cycle phase transition 0.3274322990608076 0.2510528476435243 0.8017732506981985 1.0 0.9826006256426936 37 Q8N122,P05067,P78536 3 +Guanine metabolic process 0.5101399108259632 0.2509595773498731 0.8018453618172003 1.0 0.9826006256426936 3 Q9NRG1 1 +Fatty acid transport 0.3351065504798539 0.2508838102329259 0.8019039417494049 1.0 0.9826006256426936 17 O43772 1 +Positive regulation of actin nucleation 0.5099554234769705 0.2506426882261441 0.8020903745021744 1.0 0.9826006256426936 3 Q7L576,Q9Y6W5 2 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5099554234769705 0.2506426882261441 0.8020903745021744 1.0 0.9826006256426936 3 Q7L576,Q9Y6W5 2 +Positive regulation of extracellular matrix organization 0.3797943067888256 0.2494547585441594 0.803009032326401 1.0 0.9832824673572348 5 P06400,Q14118 2 +Positive regulation of vasculature development 0.3340479214529327 0.2489687708715958 0.8033849381507174 1.0 0.9835596730235284 18 O14786 1 +Regulation of cell maturation 0.5204991087344154 0.2483165934714655 0.8038894612625147 1.0 0.983664605139014 2 Q15058 1 +Negative regulation of phosphoprotein phosphatase activity 0.344848123883257 0.2482906020488438 0.8039095698687317 1.0 0.983664605139014 10 P04899,Q15257,O75116,P17931,Q13464,P49841,Q96GX5,P62942,O75663 9 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.5202020202020328 0.2477932575565151 0.8042943719654831 1.0 0.983664605139014 2 O95817 1 +Response to muramyl dipeptide 0.4096313912009384 0.24740450975356 0.8045951843760524 1.0 0.983664605139014 4 Q04206,Q9NZZ3,P08670 3 +Non lytic viral release 0.3568787822908086 0.2473117621957403 0.8046669565602058 1.0 0.983664605139014 8 Q9UQN3,Q9Y3E7,Q9H444 3 +Purine deoxyribonucleotide biosynthetic process 0.5187165775401197 0.2451931949700722 0.8063068452268387 1.0 0.9845714549660562 2 P27707 1 +Aggresome assembly 0.5184194890077369 0.2446765058974302 0.8067069207683795 1.0 0.9846944005964744 2 O95817 1 +Cellular macromolecule localization 0.3281788944089983 0.2437526448343825 0.8074223981096937 1.0 0.9850232175922072 580 Q9Y3D6,Q15691,O14773,Q06481,P17931,P02786,Q8TAG9,Q8TEX9,Q9HD20,Q99828,Q14108,Q99523,Q9HD45,Q07954,O00410,P13473,P10619,O95373,P20290,Q13356,Q07812,Q13561,Q14247,Q12959,O15118,P11279,P63096,O43865,Q13641,O75955,P07900,Q15904,Q6IBS0,Q9UBQ0,O43731,Q9NWS0,Q15833,Q9UPT5,Q99595,Q9UNZ2,O60830,O14976,Q9Y624,O60749,P27105,P06493,P46060,P48444,P52292,P52294,P11274,P29317,Q16181,P55786,O14786,Q9NV96,Q9H444,Q13596,O94898,P15311,O14656,O14737,P84095,P20645,O00170,O43292,Q4J6C6,P05556,Q15643,Q9UEU0,Q13438,Q9H173,Q92688,O15260,P19022,Q96ES7,Q9Y4G8,P67809,Q10713,O00459,Q8N4H5,Q96PU5,Q9C0E2,O95831,Q9Y678,Q9BZH6,Q9ULC3,Q8N3F8,P35613,P35606,O60684,Q96L92,Q6GQQ9,O00560,Q13526,Q14118,Q9H4M9,P60520,Q9H6Z4,P49768,O95429,O15400,Q8TD16,P78559,P29372,P11233,O75312,Q9P2S5,Q7Z7H5,P62913,P61970,Q9UNF0,Q9H9C1,Q96D46,Q14168,P09496,O60725,Q9H223,P04792,Q9UHQ4,P08238,P09132,P54920,Q9UJA3,Q9NS69,Q8TCT9,Q14651,Q15648,Q9H2M9,Q8IVD9,P51858,Q6UWE0,Q15154,Q86Y82,Q9H6U6 135 +Protein localization to cell surface 0.3324925216274385 0.2437485908483844 0.8074255380445701 1.0 0.9850232175922072 20 Q96PU5,P78559,O94898 3 +Regulation of myotube differentiation 0.3769310162121447 0.2433990467635008 0.8076962821814899 1.0 0.985170803669542 5 Q9BYT8 1 +Negative regulation of cell substrate junction organization 0.4063614744351806 0.2412732662964027 0.8093433293293972 1.0 0.986255075505005 4 Q9P258,P63167,Q9H6U6 3 +Pentose phosphate shunt non oxidative branch 0.5163398692810561 0.2410906993928412 0.8094848210172578 1.0 0.986255075505005 2 P37837 1 +Positive regulation of neuron migration 0.3755803735724363 0.2405822900850413 0.8098788775471082 1.0 0.9863986746641866 5 Q9Y4G8 1 +Positive regulation of extracellular matrix disassembly 0.5154486036839105 0.2395705392402615 0.8106632060045611 1.0 0.9866802671522572 2 Q7Z460 1 +Nucleosome assembly 0.3276893631850386 0.2394795061134776 0.8107337859467847 1.0 0.9866802671522572 34 Q99733,Q9H0U9,P26583,Q92688,Q01105,P55209,P49321 7 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.4051062687233062 0.2389562427458132 0.811139513121091 1.0 0.9866987292389672 4 Q9BW85 1 +Rna polymerase ii preinitiation complex assembly 0.3587905303321896 0.2385977036834737 0.8114175459052704 1.0 0.9866987292389672 7 P09429 1 +Ectodermal cell differentiation 0.5148544266191444 0.2385626359584767 0.81144474080893 1.0 0.9866987292389672 2 P23229 1 +Regulation of cellular carbohydrate metabolic process 0.3297605646788736 0.237139005107344 0.8125489535250054 1.0 0.9866987292389672 26 Q14108,O75844 2 +Histone h3 deacetylation 0.4039833531510062 0.236900634564331 0.8127338776885027 1.0 0.9867411309403784 4 Q9H4L7,Q92769,Q13547 3 +Embryonic heart tube morphogenesis 0.4037914456975034 0.2365509571443446 0.8130051708908907 1.0 0.9868883583908984 4 P49768,Q04721 2 +Negative regulation of cell substrate adhesion 0.3409767718880232 0.2362697422672223 0.8132233644995788 1.0 0.9869710870255036 10 Q9BTW9,P63167,O14936,Q9P258,Q9ULV4,P42771,O43707,O95819,Q9H6U6 9 +Cardiac muscle tissue morphogenesis 0.4030774488031043 0.2352541491773673 0.8140114801196294 1.0 0.9869931104692992 4 P62942 1 +Muscle organ morphogenesis 0.4030774488031043 0.2352541491773673 0.8140114801196294 1.0 0.9869931104692992 4 P62942 1 +Ventricular cardiac muscle tissue morphogenesis 0.4030774488031043 0.2352541491773673 0.8140114801196294 1.0 0.9869931104692992 4 P62942 1 +Glutathione metabolic process 0.3311889058704932 0.2350862658776826 0.8141417782618452 1.0 0.9869931104692992 22 Q9UPY5,Q8WUX2,O75874,O00299,P26641,Q9UJ14 6 +Gene silencing by rna 0.3159122066165566 0.2340363261358021 0.8149567774816759 1.0 0.9874351965876708 45 O94992,Q9Y2W6,Q06787,Q5KU26,O75844 5 +Negative regulation of cation channel activity 0.3595906536065675 0.2328454034267124 0.8158814549041624 1.0 0.9882394408521286 6 P62942 1 +Regulation of hormone secretion 0.327214992626066 0.2326033789532273 0.81606940325116 1.0 0.9882394408521286 30 P22466 1 +Regulation of cyclase activity 0.401605231866818 0.2326010087184451 0.8160712439508608 1.0 0.9882394408521286 4 Q01518,P27361,P08754 3 +Synaptic vesicle localization 0.3325387365911796 0.2317403064829934 0.8167397233770104 1.0 0.9884902452401264 12 Q00535,P19022,O00203,P50570,O95295,P33176,O14617,O14656,Q13492,Q96A57,P35222 11 +Regulation of microtubule nucleation 0.3590246355937821 0.231560432441615 0.8168794425547776 1.0 0.9884902452401264 6 Q14203 1 +Synaptic vesicle transport 0.3324396782841882 0.2297508281667096 0.8182853960220249 1.0 0.9899664849296024 11 Q00535,O00203,P50570,O95295,P33176,O14617,O14656,Q13492,Q96A57,P35222 10 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4971834123389921 0.2296028566341301 0.8184003869028851 1.0 0.9899664849296024 3 P54578 1 +Gmp metabolic process 0.329665416734375 0.2292794298196312 0.8186517402941309 1.0 0.9900348411683954 18 Q9NRG1,P00492,Q14168,P07741 4 +Growth 0.3702838473388273 0.2291428232924016 0.8187579106044498 1.0 0.9900348411683954 190 O60271,Q9UJU6,O00560,Q5BJF2,Q14118,P61201,P05067,Q9Y4B6,P50897,P02786,Q99538,P07602,Q9BSK2,P05556,Q9BRT9,P78536,Q9UIW2,Q96K76,Q04721,Q13740,P08238,Q13308,O94813,Q8N0X7,Q7Z4V5,P11047,Q13177,Q96PU5,Q14651,Q15648,P10644,O75312,Q8N122,Q9BZH6,O43598,P43034,Q15056,Q15375,O75844,O14786 40 +Regulation of response to stress 0.4007751924790993 0.2280930421501364 0.8195739090987515 1.0 0.9901761133645988 265 Q96KB5,Q06481,P19525,P01130,O95219,O94898,Q9BXW9,P78318,O00560,P26583,P05067,P18887,Q8NCG7,Q9BUI4,Q92905,P05556,P04792,P61088,P35659,P08183,Q96K76,Q07812,P60900,P08238,P53634,P51114,Q04323,Q6YHK3,O94992,P33527,Q12959,Q02750,O96028,P54578,P11279,P10586,P28070,P07900,P25786,Q7Z4V5,P67809,Q06787,P13693,Q9Y3Z3,Q9UJ14,Q13177,P04439,Q15648,P29372,Q96J02,Q9BW85,Q7Z739,P01889,Q9H993,P04062,P09429,Q53EL6,O43657,Q6UWE0,P43034,Q96QD8,Q92692,P46108,O75844,Q08722,Q969S3,P23396 67 +Cell differentiation involved in embryonic placenta development 0.3989298454221102 0.2278513798127963 0.8197617817661207 1.0 0.9901761133645988 4 P24468,Q13188,Q9ULT8 3 +Copii coated vesicle cargo loading 0.3441500446561403 0.2277632604093143 0.8198302899569334 1.0 0.9901761133645988 9 Q15436,O94979,P53992,Q9NR31,O95487,Q15437,Q5JRA6,P62820 8 +Vesicle docking 0.3284657566189863 0.2276370147481364 0.8199284416991441 1.0 0.9901761133645988 19 Q15833,O15400,Q9UNK0,Q9UEU0,O60763,Q86Y82,Q12846,P56962 8 +Striated muscle cell proliferation 0.3685150889720661 0.2262663848219065 0.8209942414641831 1.0 0.9902413894623762 5 P10644,P06493 2 +Positive regulation of skeletal muscle tissue development 0.4948794154177689 0.2259962737842476 0.8212043184537408 1.0 0.9902413894623762 3 O75955 1 +Ossification 0.3163170043063016 0.2251908949736321 0.8218307723159946 1.0 0.9902413894623762 60 Q99523,Q9UBG0,O75844,P29317 4 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.4942050520059451 0.2249515808109858 0.8220169417679204 1.0 0.9902413894623762 3 Q6P2E9,Q96F86 2 +Regulation of notch signaling pathway 0.3485148791907552 0.2248222806988968 0.8221175322592438 1.0 0.9902413894623762 8 Q2M2I8,Q9Y6N7 2 +Collagen biosynthetic process 0.3971462544589617 0.2247364838529632 0.8221842805043809 1.0 0.9902413894623762 4 Q92769,Q92791,P08670 3 +Regulation of secretion 0.3101689029164977 0.2237786995591907 0.8229295049683194 1.0 0.9907083242462674 101 Q9Y3E7,O95219,P22466,P11279,O00560,Q06787,Q16850,Q32P28,Q7L0J3,Q4J6C6 10 +Muscle system process 0.3151132645057472 0.2229598891359077 0.8235667245342313 1.0 0.990734500193446 64 Q14126,Q02487,Q14118,P10253,Q96PU5 5 +Positive regulation of muscle cell apoptotic process 0.3471528702309964 0.2212635904354251 0.8248871980064143 1.0 0.990929873961446 8 P98175,Q53EL6 2 +Negative regulation of macrophage migration 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.990929873961446 2 P30046 1 +Negative regulation of macrophage chemotaxis 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.990929873961446 2 P30046 1 +Positive regulation of protein kinase a signaling 0.503565062388605 0.2202525577714763 0.8256744662789122 1.0 0.990929873961446 2 Q02952 1 +Prostaglandin transport 0.5035650623886048 0.220252557771476 0.8256744662789124 1.0 0.990929873961446 2 O15439 1 +Negative regulation of protein containing complex disassembly 0.3265311932831666 0.2193349447017401 0.8263891426243806 1.0 0.99122968108666 26 O15344,P46821,Q9NYL9,P35611,P52907,Q9NRR5,P47756,P58546,Q6IBS0,P29372,Q99828 11 +Negative regulation of muscle cell apoptotic process 0.393876337693216 0.2191330400406909 0.8265464139472647 1.0 0.99122968108666 4 P26358,P09601,O95817 3 +C terminal protein amino acid modification 0.4902768215704479 0.2189644786795567 0.8266777182185188 1.0 0.99122968108666 3 O60725 1 +Negative regulation of golgi to plasma membrane protein transport 0.501782531194309 0.2175069634155347 0.8278132808742444 1.0 0.9919271685850032 2 P41240 1 +Negative regulation of protein localization to nucleus 0.3456968262221749 0.2174917899703386 0.8278251045333298 1.0 0.9919271685850032 8 Q9ULC3 1 +Regulation of dna primase activity 0.3923658676264908 0.2165915248965168 0.8285266911188773 1.0 0.9924461786286536 4 Q9BRT9 1 +Positive regulation of developmental growth 0.3263409625793917 0.2144544594334146 0.8301926768765149 1.0 0.9937801140780388 25 Q9UJU6,P43034,P06493,A0MZ66,P80723,Q6IBS0,Q14651,O14786,Q96PU5 9 +Negative regulation of inflammatory response to antigenic stimulus 0.3512198577921256 0.2143257134010321 0.8302930675003442 1.0 0.9937801140780388 6 P28070 1 +Cardiac neural crest cell differentiation involved in heart development 0.4871194545819812 0.2142738414558064 0.8303335157972749 1.0 0.9937801140780388 3 P28482 1 +Production of molecular mediator of immune response 0.3226467540548194 0.2139289041501176 0.8306024997228483 1.0 0.9937801140780388 36 P02786,P04439,Q9Y3Z3,P13051 4 +Positive regulation of mitochondrial fission 0.3485562741743041 0.2139094443619948 0.8306176751597838 1.0 0.9937801140780388 7 Q9Y3D6,P11233 2 +Ether biosynthetic process 0.3506841165972616 0.2131760006508523 0.8311896867383033 1.0 0.9940688672054364 6 P49327,O15228,Q6IAN0,O00116,Q7L5N7 5 +Brainstem development 0.4988116458704763 0.2130186954981207 0.8313123804343425 1.0 0.9940688672054364 2 P22102 1 +Cellular response to hyperoxia 0.4964349376114215 0.2095067975118613 0.8340526294846071 1.0 0.996268471052285 2 O95352 1 +Mitochondrial fission 0.3252617091166142 0.2074297418215674 0.8356742570632514 1.0 0.9964628324200544 12 O00203,Q9Y3D6,O00429,Q9UDX5,P11233 5 +Catecholamine uptake involved in synaptic transmission 0.4823179791976242 0.2073479434619116 0.8357381341534569 1.0 0.9964628324200544 3 O14656,Q99497 2 +Dopamine transport 0.4823179791976242 0.2073479434619116 0.8357381341534569 1.0 0.9964628324200544 3 O14656,Q99497 2 +Catecholamine uptake 0.4823179791976242 0.2073479434619116 0.8357381341534569 1.0 0.9964628324200544 3 O14656,Q99497 2 +Monoamine transport 0.4823179791976242 0.2073479434619116 0.8357381341534569 1.0 0.9964628324200544 3 O14656,Q99497 2 +Water soluble vitamin biosynthetic process 0.4820208023774164 0.2069274823785779 0.8360664931629098 1.0 0.9966736846730012 3 Q9Y617,P14550 2 +Lipid metabolic process 0.4050595325772205 0.2063715088268288 0.8365007244676386 1.0 0.9968300299906028 290 Q9BQE5,Q8NHP8,O14773,Q06481,P01130,P61916,Q9HB40,Q9UBM7,P06280,Q86UY6,P05067,P50897,Q99538,P07602,P06865,P04066,Q07954,P22466,P07099,Q14739,Q8NCC3,P16278,P17900,Q9NX62,P34913,Q13510,O15118,Q15126,Q10713,P07686,P38571,Q15392,Q8WTV0,P04062,P35790,Q16850,O75844 37 +Immunoglobulin production 0.3239728349709617 0.2053784207055102 0.837276478700717 1.0 0.9970319835071174 26 P02786,Q9Y3Z3,P13051 3 +Negative regulation of cell matrix adhesion 0.3407738095238115 0.2049909029396397 0.8375792325097462 1.0 0.99721198035278 8 P63167,O14936,Q9P258,Q9ULV4,P42771,O95819,Q9H6U6 7 +Response to cocaine 0.3466407508783968 0.2046382235718517 0.8378547892269168 1.0 0.9972548177522964 6 P08238 1 +T cell homeostasis 0.3849583828775152 0.2045567853428653 0.8379184216656952 1.0 0.9972548177522964 4 P49327,P62753,Q07812 3 +Regulation of cellular response to heat 0.3456276026174796 0.2025376172287583 0.8394964534349549 1.0 0.9974884200956644 6 Q99543,Q99615,Q9UHD1,P49841,P25685 5 +Embryonic brain development 0.3450327186198576 0.2013114707202045 0.8404550338322023 1.0 0.9977464740206148 6 Q9Y3C6,O60508,P27635,Q9BVA1,P62995 5 +Nephron epithelium development 0.3232870872868152 0.20100402845201 0.8406954241069491 1.0 0.9978124695114228 12 Q12959,P11047,O95747,P80723,Q04721 5 +Regulation of t cell apoptotic process 0.3825802615933292 0.2008441891983518 0.8408204088961073 1.0 0.9978124695114228 4 Q9Y255,P17931,P78540 3 +Positive regulation of organelle assembly 0.3215578151586385 0.200658395745753 0.8409656933674867 1.0 0.9978124695114228 29 Q9H2M9,Q9P2S5,O95219,Q15555,Q9HBH5,O00560,Q6UWE0,Q8WUM4,Q16181,Q13283,Q9UHD8 11 +Negative regulation of receptor signaling pathway via jak stat 0.381724361318386 0.1995259489642928 0.8418513470719977 1.0 0.9983522671621884 4 Q8WXW3,O14964 2 +Negative regulation of receptor signaling pathway via stat 0.381724361318386 0.1995259489642928 0.8418513470719977 1.0 0.9983522671621884 4 Q8WXW3,O14964 2 +Phenol containing compound biosynthetic process 0.3421132644965889 0.1991914664261919 0.8421129744763856 1.0 0.9983522671621884 7 Q9UPY5,P30046,Q9Y4G8 3 +Endothelin receptor signaling pathway 0.4763744427934638 0.199119807977696 0.842169026946813 1.0 0.9983522671621884 3 P29992,P46109 2 +Fatty acid homeostasis 0.4760772659732558 0.1987183875602892 0.8424830396803447 1.0 0.9983522671621884 3 P17174,P28340 2 +Autophagy of nucleus 0.3804994054696701 0.1976558078104347 0.8433143677417199 1.0 0.999032340538412 4 Q9NT62,Q9Y4P8,O95352 3 +Peripheral nervous system axon regeneration 0.4739970282317996 0.1959349874182385 0.8446610519966424 1.0 0.999840192703172 3 P07196,P46821 2 +Positive regulation of lymphocyte apoptotic process 0.4739789235890622 0.1959109667156866 0.8446798534054896 1.0 0.999840192703172 3 Q07812 1 +Regulation of fertilization 0.4866310160427946 0.1957540923143408 0.8448026438194332 1.0 0.999840192703172 2 P35579 1 +Regulation of phosphorus metabolic process 0.3914182385064275 0.194739158050345 0.8455971550399293 1.0 0.9998977322827388 245 O60271,P23396,P54619,Q96KB5,Q9P287,P01130,P78318,Q15118,P17931,O00560,Q13526,P67870,Q14118,P05067,Q9Y6N7,P02786,P62942,Q9H223,Q96A49,Q99828,P32780,P78536,P04792,Q07954,O75874,O00410,O95373,Q86XL3,Q07812,P49768,P08238,Q96B36,P51114,Q6YHK3,O94992,O95429,Q12959,Q02750,O94813,O75955,Q9Y4G8,Q06787,Q86VI3,O00459,Q9Y376,Q13177,Q8ND04,Q8WTV0,P10644,Q8N122,P04062,Q53EL6,Q15375,Q86Y37,P29317,Q969S3,O14786 57 +Oocyte differentiation 0.336011904761907 0.1932740825327794 0.846744322775419 1.0 1.0 8 P35222,Q9Y2W6,Q12768,Q15645,Q9H6S0,O14965,P30153 7 +Regulation of histone ubiquitination 0.3315287647527879 0.1929515514853643 0.8469969112964941 1.0 1.0 9 Q96FW1,P61088 2 +Peptidyl tyrosine dephosphorylation 0.3190132298942701 0.1924745162806069 0.8473705277606036 1.0 1.0 14 P10586,Q9ULE6,P24666,P51452,Q8NCE2,Q99956 6 +Cellular response to chemical stress 0.3014606080148213 0.1909751198474285 0.8485450858743373 1.0 1.0 81 Q7Z2K6,P33527,P23396,P04062,Q9BXW9,P05198,P04792,Q15118,Q9NR28,O95747,Q9Y376,Q99720,O95831,P11166 14 +Magnesium ion homeostasis 0.4700593784066512 0.1907931416228737 0.8486876621757558 1.0 1.0 3 Q8NE01 1 +Vitamin b6 metabolic process 0.4818775995246722 0.1895068446310992 0.8496955910565567 1.0 1.0 2 Q9Y617 1 +Positive regulation of erad pathway 0.3748513674197333 0.1892838877310223 0.8498703227859072 1.0 1.0 4 P51572,O43765,Q4ZIN3 3 +Response to redox state 0.4812834224599071 0.1887450435784622 0.8502926463622726 1.0 1.0 2 Q9UPY5 1 +Pyrimidine nucleobase biosynthetic process 0.3370846155617337 0.18815612226538 0.8507542674522248 1.0 1.0 7 P17812,Q9NRF8 2 +Regulation of intracellular protein transport 0.3049236841196478 0.1856529784797064 0.8527169048818619 1.0 1.0 76 Q9NV96,Q9Y3D6,Q99828,Q13438,O00410,Q92688,P49768,P08238,O95429,O00459,Q9C0E2,O75312,Q9ULC3,P27105,P06493,P46060,Q15154,P55786,Q9H6U6 19 +Regulation of vesicle size 0.3461195361284672 0.1855983677813636 0.8527597336489858 1.0 1.0 5 P20337,P20339,Q96CW1,Q12768 4 +Positive regulation of phosphatase activity 0.3455248290217157 0.1846167820608336 0.8535296220322892 1.0 1.0 5 P08238,Q13464,Q15257,O14974 4 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.3231089934484755 0.1841323837000404 0.8539096022801986 1.0 1.0 10 Q14254,Q12959,Q96RT1,O60716,Q14160,Q15334,Q14118,Q96QK1,Q9NQX3 9 +Negative regulation of oxidative stress induced neuron death 0.3449301219149636 0.1836402894815793 0.8542956541523739 1.0 1.0 5 Q9UPY5,Q15233,Q99497,P63244 4 +Centromeric sister chromatid cohesion 0.3449301219149622 0.183640289481577 0.8542956541523756 1.0 1.0 5 Q9GZZ1,P41227,O60566,P30153 4 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.4762329174094021 0.1824396258429786 0.855237730661661 1.0 1.0 2 Q13247 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.4762329174094021 0.1824396258429786 0.855237730661661 1.0 1.0 2 Q13247 1 +Secretion by tissue 0.4756387403446368 0.1817176840790621 0.8558042871467013 1.0 1.0 2 Q9H4A3 1 +Pancreatic juice secretion 0.4756387403446368 0.1817176840790621 0.8558042871467013 1.0 1.0 2 Q9H4A3 1 +Reactive oxygen species metabolic process 0.3142740083335573 0.1816864559667032 0.855828795635827 1.0 1.0 40 P51790,P42785 2 +Glandular epithelial cell differentiation 0.3339139205570149 0.1814039538645762 0.8560505156315235 1.0 1.0 7 P19022 1 +Regulation of protein export from nucleus 0.3180727210234418 0.1810158486424261 0.856355136095432 1.0 1.0 16 Q92688 1 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.4750445632798665 0.1809999006857292 0.8563676539680964 1.0 1.0 2 O43765 1 +Regulation of protein folding 0.3431460005947173 0.1807413589417809 0.8565705936331747 1.0 1.0 5 Q9Y2G5,Q9UL15,O14737,Q9H2J4 4 +Membrane lipid biosynthetic process 0.3202747906022508 0.1806973354907217 0.8566051503305254 1.0 1.0 23 Q13510 1 +Protein hydroxylation 0.3170211307933154 0.1804735114747004 0.8567808477306889 1.0 1.0 15 Q9H9C1,O75718,Q32P28,P13674 4 +Rna guanine n7 methylation 0.4616325195056261 0.1803424972365184 0.856883694595072 1.0 1.0 3 P57081 1 +Regulation of clathrin dependent endocytosis 0.3683115338882186 0.1801029177325447 0.8570717720463352 1.0 1.0 4 Q8IYB5,P50570,Q2M2I8 3 +Negative regulation of signaling receptor activity 0.3331550307713427 0.1798116167942041 0.8573004633831289 1.0 1.0 7 P49768,Q9BRG1,Q9UNH7 3 +Regulation of glial cell migration 0.4738562091503355 0.179576778957557 0.8574848360111205 1.0 1.0 2 P46109 1 +Negative regulation of schwann cell proliferation 0.4738562091503339 0.1795767789575554 0.8574848360111218 1.0 1.0 2 Q9UPY3 1 +Negative regulation of glial cell proliferation 0.4738562091503339 0.1795767789575554 0.8574848360111218 1.0 1.0 2 Q9UPY3 1 +Axoneme assembly 0.4606240713224385 0.1791419698544797 0.8578262278271933 1.0 1.0 3 Q86Y56,Q15555 2 +Positive regulation of inflammatory response to antigenic stimulus 0.4711824123588943 0.1764351425068377 0.8599520979646169 1.0 1.0 2 Q99497 1 +Myotube cell development 0.3647443519619486 0.1753253960129804 0.8608239576915686 1.0 1.0 4 Q96TA1,Q08209,Q8NEZ5 3 +Positive regulation of protein localization 0.3332845770933933 0.1741539530797035 0.8617444725656394 1.0 1.0 138 P05556,Q9NV96,Q07954,O94898,P27105,P84095,O00459,Q92688,P29317,P02786,P55786 11 +Regulation of protein localization to nucleus 0.3102133953008695 0.1732207111878587 0.862477944546165 1.0 1.0 54 O75312,P49768,Q6GQQ9,Q13526,Q9ULC3,O00459,P02786 7 +Guanine nucleotide transport 0.4552748885586943 0.1729511219203905 0.8626898475935294 1.0 1.0 3 O15439,Q8TDW0 2 +Guanine nucleotide transmembrane transport 0.4552748885586943 0.1729511219203905 0.8626898475935294 1.0 1.0 3 O15439,Q8TDW0 2 +Negative regulation of protein dephosphorylation 0.3138619598514042 0.1715755003252029 0.8637712697050286 1.0 1.0 13 P17931,P62942,P62258,Q12972 4 +Aggrephagy 0.4537890044576542 0.1712840229240052 0.8640004426734844 1.0 1.0 3 P42858,O95817 2 +Pigment granule localization 0.3369582784844072 0.1710416855828201 0.8641909881734404 1.0 1.0 5 Q13561,Q96AX1 2 +Cellular response to ionizing radiation 0.3157800034840013 0.1706625913001988 0.8644890790383681 1.0 1.0 19 O75844 1 +Eyelid development in camera type eye 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 1.0 2 Q92769 1 +Positive regulation of sprouting angiogenesis 0.464349376114092 0.1687818783502657 0.8659682127987238 1.0 1.0 2 P14618 1 +Adherens junction maintenance 0.464349376114089 0.1687818783502623 0.8659682127987265 1.0 1.0 2 Q96AC1 1 +Positive regulation of multicellular organism growth 0.3574886003055905 0.1661040043494695 0.8680751029199305 1.0 1.0 4 Q14651 1 +Segmentation 0.3112395884461805 0.1651687006284824 0.8688112001551658 1.0 1.0 14 P49768,O95747,Q9Y2W6,O14786 4 +Histone h3 k36 methylation 0.3258684841129523 0.1647099228385137 0.869172306365195 1.0 1.0 6 Q96ST2 1 +Deoxyribonucleoside metabolic process 0.4469539375928696 0.1639062432586381 0.8698049521635951 1.0 1.0 3 P00491,P23919 2 +Negative regulation of dna dependent dna replication 0.3546373365041457 0.1626605379386817 0.8707857192651294 1.0 1.0 4 P54132,Q7Z7L1,Q9UNS1 3 +Antigen processing and presentation via mhc class ib 0.4454680534918295 0.1623650064054672 0.8710184259938596 1.0 1.0 3 O00203,Q03519 2 +Synaptic vesicle endosomal processing 0.4454680534918294 0.1623650064054672 0.8710184259938596 1.0 1.0 3 O00203,Q15075 2 +Anaphase promoting complex dependent catabolic process 0.3098004170390306 0.1618949757180535 0.871388559421669 1.0 1.0 11 Q16763,Q13042,Q9UJX3,Q9UJX4,Q12834,Q9H1A4,Q9UJX2,P30260,P24941,Q13618 10 +Positive regulation of wnt signaling pathway 0.3153063951348742 0.1606174589189026 0.8723947032081172 1.0 1.0 21 Q13526,O75787,Q96K76,Q13308,Q9H2V7 5 +Negative regulation of intracellular transport 0.3131790129390323 0.1594054564417559 0.8733494402606432 1.0 1.0 19 O95429,Q9UMY4,Q07960,Q13438,Q9ULC3,P46060 6 +Taurine transport 0.4551396316102327 0.1593006972153101 0.8734319714752716 1.0 1.0 2 Q8TDW0 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.4551396316102327 0.1593006972153101 0.8734319714752716 1.0 1.0 2 Q8TDW0 1 +Response to hydrogen peroxide 0.3136427332033493 0.158563366523552 0.8740128928506128 1.0 1.0 28 Q99720,O95831 2 +Regulation of lipopolysaccharide mediated signaling pathway 0.4404160475482931 0.1572897356557045 0.8750165093305384 1.0 1.0 3 P14174,P32119 2 +Cellular response to cold 0.4404160475482929 0.1572897356557042 0.8750165093305386 1.0 1.0 3 Q13217,P17612 2 +Phenol containing compound metabolic process 0.3091557675204414 0.1572470994549888 0.875050109988339 1.0 1.0 12 Q9UPY5,P00492,Q9Y4G8,P30046,P58546,Q15648 6 +Thioester metabolic process 0.3137140007396165 0.1561857952035761 0.8758865731123262 1.0 1.0 36 Q9UMR5 1 +Negative regulation of catabolic process 0.3100196734720219 0.1551805104738093 0.8766790125454869 1.0 1.0 109 Q96KB5,O94898,O00560,Q13526,P60520,P10619,Q92530,P49768,P08238,Q04323,O15118,Q9H814,Q06787,P67809,P78559,Q9UMY4,P62913,Q16850,Q08J23 19 +Regulation of golgi organization 0.3192733471292592 0.155094105067555 0.8767471294287525 1.0 1.0 8 P28482,Q02750,P36507,Q9Y4I1,P27361 5 +Double strand break repair via break induced replication 0.3161655254539972 0.1542930610452347 0.8773786682873481 1.0 1.0 9 Q9BRT9,P49736,P33991,P33992,P25205,Q14566,O75419,P33993 8 +Positive regulation of gliogenesis 0.3118313402635419 0.1542067309247617 0.8774467351631516 1.0 1.0 10 Q15382,Q14118 2 +Positive regulation of amyloid beta formation 0.3460166468489821 0.1528573531349409 0.8785107678584243 1.0 1.0 4 O75116,Q04206,P49840 3 +Regulation of receptor clustering 0.3457193816884584 0.1525354098345363 0.8787646641785023 1.0 1.0 4 P46109,Q9UPY5,Q15334 3 +Protein localization to golgi apparatus 0.315336634228505 0.152327300248301 0.8789287936840959 1.0 1.0 9 Q8TD16,O14976,Q9H4A6 3 +Cellular response to abiotic stimulus 0.3056281439196185 0.1518904447555724 0.8792733448305505 1.0 1.0 68 Q96KB5,P05198,Q9H1E3,Q9Y624,Q06787,Q14118,P62993,Q96K76,Q96QD8,Q9Y376,O75844,P11166 12 +Respiratory chain complex iii assembly 0.3182168048869312 0.151678094569883 0.8794408352486864 1.0 1.0 6 Q9BSK2 1 +Negative regulation of protein sumoylation 0.3448275862068891 0.1515759468644616 0.8795214057930685 1.0 1.0 4 Q04206,Q9NVN8,Q99497 3 +Regulation of myosin light chain phosphatase activity 0.3442330558858376 0.1509415990981422 0.8800217850647012 1.0 1.0 4 O75116,Q13464,O14974 3 +Neurotransmitter receptor transport 0.3226286054118438 0.1506747630030379 0.8802322821243493 1.0 1.0 5 O00291,Q14160,Q96QK1,O14617 4 +Antigen processing and presentation of lipid antigen via mhc class ib 0.4453357100416021 0.1502218679083363 0.8805895735656164 1.0 1.0 2 O00203 1 +Synaptic vesicle recycling via endosome 0.4453357100416021 0.1502218679083363 0.8805895735656164 1.0 1.0 2 O00203 1 +Nk t cell differentiation 0.4453357100416021 0.1502218679083363 0.8805895735656164 1.0 1.0 2 O00203 1 +Regulation of nk t cell differentiation 0.4453357100416021 0.1502218679083363 0.8805895735656164 1.0 1.0 2 O00203 1 +Vesicle transport along microtubule 0.3053321417932783 0.1496774287391338 0.8810191168024812 1.0 1.0 11 O00203,P27695,O95295,P33176,Q9Y2T2,O14617,P43034,Q12756,P42858,P62820 10 +Tripartite regional subdivision 0.4307702979205724 0.1482938856299201 0.8821108405705036 1.0 1.0 3 Q9Y2W6 1 +Endosomal vesicle fusion 0.4294205052005962 0.1471062113168069 0.8830481872970837 1.0 1.0 3 Q9P2R3,Q8WUH2 2 +Regulation of inflammatory response to antigenic stimulus 0.3150470647314751 0.1462094637948448 0.8837560348197016 1.0 1.0 8 P28070 1 +Response to atp 0.4396910279263347 0.1454501000811036 0.884355511050344 1.0 1.0 2 Q96RD7 1 +Gtp biosynthetic process 0.4390968508615716 0.1449666080576845 0.8847372361526007 1.0 1.0 2 P15531 1 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.3171497981759091 0.1436499848328518 0.8857768677637166 1.0 1.0 5 Q96TA1,P46934 2 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.3171497981759091 0.1436499848328518 0.8857768677637166 1.0 1.0 5 Q96TA1,P46934 2 +Positive regulation of torc1 signaling 0.3362068965517162 0.1427873668546687 0.8864581146315436 1.0 1.0 4 Q9Y4R8,Q9NWS0,Q9P2J5 3 +Microtubule organizing center organization 0.307370135968745 0.1418018521904937 0.8872365210185762 1.0 1.0 41 Q8TEY7,Q9UQN3,Q9Y3E7,Q9UNZ2,O94927,Q7Z4H7,P43034,P43487,P06493,Q15154,P41208,Q14203,Q9H6U6 13 +Focal adhesion assembly 0.3116360546814684 0.14104174478591 0.8878369643729698 1.0 1.0 22 Q14247,P63000,Q9P258,Q9H2G2,Q9H6U6,P12814,Q7Z460,P51452,Q96AC1,P11274,O95819,O75116,O14786 13 +Ruffle organization 0.3073384073387089 0.1407139998880382 0.8880958848331286 1.0 1.0 16 O95429,P63000,Q9UJU6,P84095,P07737 5 +Meiosis ii cell cycle process 0.4210995542347716 0.1401598202036397 0.8885337173020624 1.0 1.0 3 P30153,Q96GX5 2 +Multicellular organismal response to stress 0.310826888756685 0.1399493156750263 0.8887000363918769 1.0 1.0 6 P17655,Q08209,Q04637,P06730,P42345 5 +Paranodal junction assembly 0.4322638146167609 0.1396572160635069 0.8889308316633173 1.0 1.0 2 O15228 1 +Synaptic vesicle cytoskeletal transport 0.3317479191438703 0.1385806973404583 0.8897814974038833 1.0 1.0 4 O00203,O14617,O95295 3 +Platelet morphogenesis 0.3113157120826911 0.1379652261835346 0.8902679001659419 1.0 1.0 7 P35579,Q96AX1,Q06124,O75083,Q99828 5 +Angiotensin activated signaling pathway 0.4169390787518592 0.1369234061093571 0.8910913376788405 1.0 1.0 3 O75116,O43865 2 +Membrane to membrane docking 0.4169390787518592 0.1369234061093571 0.8910913376788405 1.0 1.0 3 P15311,P26038 2 +Negative regulation of nucleocytoplasmic transport 0.3105639423658031 0.1366624479769027 0.8912976131418333 1.0 1.0 7 Q9ULC3 1 +Regulation of mitochondrial fission 0.308346304798033 0.1362482940105388 0.8916249979984228 1.0 1.0 9 Q9Y3D6,P11233 2 +Hippocampus development 0.3075411816109073 0.1358551372444301 0.8919358018573893 1.0 1.0 18 P46108,P43034,P18887 3 +Positive regulation of lyase activity 0.4269162210338841 0.1358152966327316 0.8919672981495805 1.0 1.0 2 Q99497 1 +Regulation of mitochondrial electron transport nadh to ubiquinone 0.4269162210338841 0.1358152966327316 0.8919672981495805 1.0 1.0 2 Q99497 1 +Neuroblast proliferation 0.3042619653241607 0.1354776700539873 0.8922342181919052 1.0 1.0 10 P43034,Q8NCG7 2 +Trophoblast giant cell differentiation 0.4239453357100484 0.1337957711548741 0.8935640712593957 1.0 1.0 2 Q9ULT8 1 +Fibroblast growth factor receptor signaling pathway 0.3060678167757209 0.1328393726778056 0.8943204153853366 1.0 1.0 6 P46109,Q06124,P46940,Q8NEM2,P35222 5 +Viral transcription 0.3050208909895218 0.1323508846616398 0.8947067611928492 1.0 1.0 16 Q9H1E3 1 +Membrane raft assembly 0.3073657096832357 0.1321280867063058 0.8948829806855076 1.0 1.0 5 Q9UNF0,O75955 2 +Meiotic sister chromatid cohesion centromeric 0.4209744503862203 0.1318561219864789 0.8950980950980374 1.0 1.0 2 P30153 1 +Nucleotide binding oligomerization domain containing 2 signaling pathway 0.4095096582466585 0.131523306765425 0.8953613505857017 1.0 1.0 3 Q04206,P0DMV9 2 +Monocyte differentiation 0.3045806067816687 0.1306883001566981 0.896021888082329 1.0 1.0 6 P49327,P35579,O00625,Q15648,Q9UKV3 5 +Translational readthrough 0.4188948306595494 0.130544957083272 0.8961352878300404 1.0 1.0 2 P57772 1 +Cellular response to brain derived neurotrophic factor stimulus 0.4188948306595477 0.1305449570832709 0.8961352878300413 1.0 1.0 2 Q05086 1 +Negative regulation of translational elongation 0.4188948306595436 0.1305449570832684 0.8961352878300433 1.0 1.0 2 P49458 1 +Cell fate commitment 0.3075600421555002 0.1303772212380213 0.8962679875711745 1.0 1.0 20 P05556,P49768,O14786 3 +Respiratory burst involved in inflammatory response 0.4183006535947876 0.1301772849283743 0.8964261656419215 1.0 1.0 2 P32119 1 +Respiratory burst involved in defense response 0.4183006535947876 0.1301772849283743 0.8964261656419215 1.0 1.0 2 P32119 1 +Positive regulation of myeloid leukocyte differentiation 0.3064564117822097 0.1297063063629202 0.8967987929654444 1.0 1.0 7 Q14790,O00165,P06400,Q04721,Q9UKV3,P17252 6 +Negative regulation of cell morphogenesis involved in differentiation 0.4062407132243704 0.1292969966389732 0.8971226478221666 1.0 1.0 3 Q9P258,O43707 2 +Response to fibroblast growth factor 0.3062500000000021 0.128708410254276 0.8975883803469906 1.0 1.0 8 P46109,P48506,Q06124,P46940,Q8NEM2,P48507,P35222 7 +Regulation of histone h2b ubiquitination 0.4047548291233305 0.1283145533613024 0.8979000483935382 1.0 1.0 3 O75150,Q5VTR2 2 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4038632986627062 0.1277338377569098 0.89835961076944 1.0 1.0 3 Q99497,Q07820 2 +Response to x ray 0.2985728529711862 0.1271545939185335 0.8988180423910259 1.0 1.0 12 Q9H1E3 1 +Positive regulation of nad p h oxidase activity 0.4014858841010421 0.1262170207861928 0.899560138474292 1.0 1.0 3 Q99497,P08754 2 +Regulation of nad p h oxidase activity 0.4014858841010421 0.1262170207861928 0.899560138474292 1.0 1.0 3 Q99497,P08754 2 +Regulation of translational initiation 0.3023751776624895 0.124751286139506 0.9007204540370188 1.0 1.0 43 P23588,Q13144,P04792,P19525,Q06787,Q15056,P55010,A9UHW6,Q6PKG0,Q7Z739,P05198 11 +Negative regulation of chromatin binding 0.3979197622585459 0.1240271105669283 0.9012938096590706 1.0 1.0 3 O14981,Q7Z5K2 2 +Positive regulation of connective tissue replacement 0.3979197622585458 0.124027110566928 0.9012938096590708 1.0 1.0 3 O75116,Q13464 2 +Regulation of connective tissue replacement 0.3979197622585458 0.124027110566928 0.9012938096590708 1.0 1.0 3 O75116,Q13464 2 +Positive regulation of tissue remodeling 0.3979197622585458 0.124027110566928 0.9012938096590708 1.0 1.0 3 O75116,Q13464 2 +Connective tissue replacement 0.3979197622585458 0.124027110566928 0.9012938096590708 1.0 1.0 3 O75116,Q13464 2 +C terminal protein lipidation 0.4055258467023231 0.1229888721000303 0.9021159098425986 1.0 1.0 2 O95352 1 +Regulation of genetic imprinting 0.4046345811051862 0.1225364420584437 0.902474186850013 1.0 1.0 2 Q13263 1 +Genomic imprinting 0.4046345811051862 0.1225364420584437 0.902474186850013 1.0 1.0 2 Q13263 1 +Inositol lipid mediated signaling 0.3022042458646322 0.1223540310175487 0.9026186428315416 1.0 1.0 16 P15311,Q05086,Q10713,O00459,P46934 5 +Response to interleukin 7 0.2983716432298387 0.1216748844373842 0.9031565047366548 1.0 1.0 10 P67809 1 +Myeloid cell apoptotic process 0.3013153767378229 0.1213849989260616 0.9033860981409352 1.0 1.0 7 P42771,P78536 2 +Gamma aminobutyric acid signaling pathway 0.4013666072489691 0.1209296100280033 0.9037467888637098 1.0 1.0 2 P55011 1 +Positive regulation of granulocyte chemotaxis 0.2965517128232225 0.1208731905636632 0.9037914772781976 1.0 1.0 5 O00429,P63000 2 +Positive regulation of neutrophil migration 0.2965517128232225 0.1208731905636632 0.9037914772781976 1.0 1.0 5 O00429,P63000 2 +Ribosome disassembly 0.2963783893616102 0.1207050874973195 0.9039246292231762 1.0 1.0 5 O43583 1 +Positive regulation of embryonic development 0.3018240141269389 0.120412651303286 0.9041562700301672 1.0 1.0 8 Q96TA1,O95747,P43034 3 +Trail activated apoptotic signaling pathway 0.3986928104575334 0.1196745146145526 0.904740989630476 1.0 1.0 2 Q99497 1 +Maintenance of protein location in cell 0.3060057182124573 0.1192179599836526 0.905102678115684 1.0 1.0 21 O43731 1 +Hair cell differentiation 0.2997935294437092 0.1178019444603527 0.9062245888209276 1.0 1.0 9 Q14651,P18074,P43034,O95487 4 +Negative regulation of striated muscle cell apoptotic process 0.3936423054070175 0.11744500176945 0.9065074245426878 1.0 1.0 2 O95817 1 +Activation induced cell death of t cells 0.3848439821693928 0.1168352635780072 0.9069905988133576 1.0 1.0 3 P49327,P62753 2 +Positive regulation of multicellular organismal process 0.3702978560406686 0.1164246517043736 0.907315999006665 1.0 1.0 211 P23396,Q06481,P19525,O95219,Q9UJU6,P17931,O00560,P26583,Q14118,A0MZ66,P05067,Q9Y6N7,P02786,Q9BUI4,Q13283,P55209,Q99828,P05556,P78536,P04792,Q07954,P22466,P04920,Q9UIW2,O75787,P80723,Q04721,P49768,Q14247,Q02750,O96028,O94813,O75955,Q13641,P07900,Q86VI3,O95747,Q14651,P04439,Q15648,Q96J02,P04062,P09429,Q14444,P43034,O60684,Q15382,Q9UQB8,O14786 49 +Regulation of cellular amino acid metabolic process 0.3839524517087688 0.1163907982289638 0.9073428277797206 1.0 1.0 3 Q9UPY5,Q99497 2 +Dna damage response signal transduction resulting in transcription 0.3824665676077285 0.1156625168809366 0.9079200140117194 1.0 1.0 3 O96017,Q9UNS2 2 +Positive regulation of execution phase of apoptosis 0.3824665676077286 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q13625,P63167 2 +Positive regulation of rna polymerase ii transcription preinitiation complex assembly 0.3824665676077285 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q86VP6,P62333 2 +Negative regulation of helicase activity 0.3824665676077287 0.1156625168809366 0.9079200140117194 1.0 1.0 3 P33993,P49736 2 +Replicative senescence 0.3824665676077285 0.1156625168809366 0.9079200140117194 1.0 1.0 3 O96017,P42771 2 +Peptidyl lysine hydroxylation 0.2974453623769136 0.1154021953610923 0.9081263389432728 1.0 1.0 7 Q9H9C1 1 +Spermatid differentiation 0.3067618745697694 0.1148195903565845 0.9085881208928313 1.0 1.0 24 P26583,P43034,Q92692,Q9GZP4,Q08J23,Q96SB4,Q99828 7 +Regulation of glutamine family amino acid metabolic process 0.3838383838383915 0.1136139553184814 0.9095438242429408 1.0 1.0 2 Q9UPY5 1 +Positive regulation of t cell apoptotic process 0.3823529411764774 0.1130874525881129 0.9099612225598674 1.0 1.0 2 Q9Y255 1 +Bone marrow development 0.3823529411764771 0.1130874525881129 0.9099612225598674 1.0 1.0 2 Q9Y3A5 1 +Methionine metabolic process 0.2969678953626548 0.1130630598001883 0.9099805611609064 1.0 1.0 4 P11586,Q99707,Q13126 3 +Sulfur amino acid biosynthetic process 0.2969678953626548 0.1130630598001883 0.9099805611609064 1.0 1.0 4 P11586,Q99707,Q13126 3 +Methionine biosynthetic process 0.2969678953626548 0.1130630598001883 0.9099805611609064 1.0 1.0 4 P11586,Q99707,Q13126 3 +Positive regulation of cell cell adhesion mediated by cadherin 0.3759286775631522 0.1126390572461528 0.910316718875376 1.0 1.0 3 Q07157,O75955 2 +Regulation of cell cell adhesion mediated by cadherin 0.3759286775631522 0.1126390572461528 0.910316718875376 1.0 1.0 3 Q07157,O75955 2 +Piecemeal microautophagy of the nucleus 0.3802733214497988 0.1123730339638113 0.9105276356603856 1.0 1.0 2 O95352 1 +Lysosomal microautophagy 0.3802733214497988 0.1123730339638113 0.9105276356603856 1.0 1.0 2 O95352 1 +Regulation of synaptic vesicle endocytosis 0.3714710252600317 0.1107406936955062 0.9118219755187866 1.0 1.0 3 Q13464,O14656 2 +Positive regulation of synaptic vesicle recycling 0.3714710252600317 0.1107406936955062 0.9118219755187866 1.0 1.0 3 Q9Y263,O14656 2 +Cellular response to peptidoglycan 0.3725490196078501 0.1099412011391958 0.9124560067922868 1.0 1.0 2 Q04206 1 +Response to peptidoglycan 0.3725490196078501 0.1099412011391958 0.9124560067922868 1.0 1.0 2 Q04206 1 +Positive regulation of synaptic vesicle endocytosis 0.3713606654783217 0.1095967337140651 0.9127292011728124 1.0 1.0 2 O14656 1 +Positive regulation of alpha beta t cell differentiation 0.2895362663495781 0.1091201662995955 0.9131071800048772 1.0 1.0 4 P00491,O00203,O14617 3 +Synaptonemal complex organization 0.2879238548482962 0.1088619665245451 0.9133119736218434 1.0 1.0 6 Q15645,P54652,P53350,P46379,Q92791 5 +Positive regulation of protein import 0.3023480506864545 0.1084580520980858 0.9136323537469142 1.0 1.0 20 O75312,O00410,P06493,O00459,P49768,P08238 6 +Fear response 0.3636113738535643 0.1076975820576036 0.9142355875970334 1.0 1.0 3 P06730 1 +Protein modification by small protein removal 0.3009442062608246 0.1073480658323248 0.914512853795038 1.0 1.0 50 Q8TEY7,Q96ES7,Q9NWV8,Q9H8M7,Q6GQQ9,P54578,Q7L5N1,O14656,P06493,P61201,Q96K76,P45974,Q9NZM5,Q9H9Q2,Q96J02,Q92905,Q96FW1,Q04323 18 +Regulation of amyloid precursor protein catabolic process 0.2977719239657074 0.107002277118759 0.9147871732490548 1.0 1.0 16 P49755,Q96P70,Q13526,P62942,Q04206 5 +Sodium ion export across plasma membrane 0.3612596553773148 0.1069634169925892 0.9148180022141504 1.0 1.0 2 P54709 1 +Membrane repolarization during action potential 0.3613670133729589 0.1068965462244428 0.914871053205918 1.0 1.0 3 P62258,P21333 2 +Membrane repolarization during cardiac muscle cell action potential 0.3613670133729589 0.1068965462244428 0.914871053205918 1.0 1.0 3 P62258,P21333 2 +Cellular potassium ion homeostasis 0.3613670133729587 0.1068965462244428 0.914871053205918 1.0 1.0 3 P54709,P55011 2 +Postsynaptic actin cytoskeleton organization 0.2801280697481345 0.1065868072549896 0.915116785242335 1.0 1.0 5 Q9UJU6 1 +Response to insecticide 0.3582887700534835 0.1062830934956688 0.9153577450438496 1.0 1.0 2 P46821 1 +Small nucleolar ribonucleoprotein complex assembly 0.2771335117454725 0.1043261791773291 0.9169105032877264 1.0 1.0 5 Q9Y230,P55769,Q9NWS0,Q96HR8 4 +Regulation of type i interferon mediated signaling pathway 0.2872001680446576 0.1043073728793012 0.9169254271207624 1.0 1.0 11 Q9Y3Z3,Q7Z739 2 +Protein o linked fucosylation 0.3475935828877096 0.1041509243527397 0.917049578775544 1.0 1.0 2 Q9Y2G5 1 +Fucosylation 0.3475935828877096 0.1041509243527397 0.917049578775544 1.0 1.0 2 Q9Y2G5 1 +Response to platelet derived growth factor 0.2894971734602812 0.1038657988868897 0.9172758488009644 1.0 1.0 7 P22681,Q13547,P35241,P46940,Q96A49,P56192 6 +Positive regulation of wound healing spreading of epidermal cells 0.345216874628653 0.1037393188882214 0.9173762230151504 1.0 1.0 2 Q96AC1 1 +Neurotransmitter gated ion channel clustering 0.3473997028231819 0.1025357725260475 0.9183314200995064 1.0 1.0 3 Q9UPY5,Q15334 2 +Dna replication dependent chromatin organization 0.2885228342359895 0.1025205127628896 0.9183435318021111 1.0 1.0 7 Q8TEX9,P49321 2 +Response to toxic substance 0.3010186807092 0.1022184812845836 0.9185832586476024 1.0 1.0 53 P08183,P34913,P07099 3 +Positive regulation of glucose import 0.3345216874628727 0.1021341561206571 0.9186501900983144 1.0 1.0 2 Q06124 1 +Synaptic vesicle budding 0.3459138187221418 0.1021311669799864 0.91865256268088 1.0 1.0 3 O00203,O14617 2 +Regulation of wound healing spreading of epidermal cells 0.3453194650817257 0.1019723245243779 0.918778642379118 1.0 1.0 3 Q7Z460,Q96AC1 2 +Gastrulation with mouth forming second 0.3447251114413097 0.1018151779645628 0.918903377985713 1.0 1.0 3 Q4VCS5,O60701 2 +Isotype switching to iga isotypes 0.3404563496662489 0.1007352632145849 0.919760617745548 1.0 1.0 3 O96028 1 +Schwann cell proliferation 0.3402674591381894 0.1006894138379095 0.9197970151972296 1.0 1.0 3 Q96G23,Q9UPY3 2 +Negative regulation of tyrosine phosphorylation of stat protein 0.3402674591381891 0.1006894138379092 0.91979701519723 1.0 1.0 3 Q8WXW3,P30153 2 +Dorsal ventral pattern formation 0.2865218684915277 0.0998045332846563 0.920499508982815 1.0 1.0 7 P35222,P17612,P49768,Q9Y366,P17252,Q8NCM8 6 +Granulocyte activation 0.2898809523809544 0.0997301398111255 0.9205585717130282 1.0 1.0 8 Q15833,Q96JM3,P51809,Q15046,P11274,O00186,Q12846 7 +Meiotic chromosome condensation 0.2797275326512381 0.0996099980118672 0.9206539560413018 1.0 1.0 6 Q6IBW4 1 +Protein localization to microtubule 0.2905790280734028 0.0994555281760381 0.9207765961475408 1.0 1.0 9 P78559,Q15691,P29372,Q15555 4 +Positive regulation of myeloid cell apoptotic process 0.2893642305407112 0.0985695934126647 0.9214800133590528 1.0 1.0 2 P42771 1 +Imp catabolic process 0.2866904337492676 0.0984681147611195 0.9215605896227752 1.0 1.0 2 P00491 1 +Allantoin metabolic process 0.2866904337492676 0.0984681147611195 0.9215605896227752 1.0 1.0 2 P00491 1 +Alditol biosynthetic process 0.3239227340267481 0.0972908535056899 0.9224954193878868 1.0 1.0 3 P17174,A6NDG6 2 +Positive regulation of histone ubiquitination 0.2559453032104587 0.0965796833098309 0.9230601914273964 1.0 1.0 4 O75150,Q5VTR2,Q6PD62 3 +Response to auditory stimulus 0.3101022420166762 0.0951810558538869 0.9241710169034716 1.0 1.0 3 Q8N2K0 1 +Uv protection 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P39748,P18074 2 +Nucleotide excision repair dna incision 0.3096582466567626 0.0951232196439493 0.9242169550904548 1.0 1.0 3 Q16658,P18074 2 +Subpallium development 0.3079454056346893 0.0949054211863898 0.9243899504746892 1.0 1.0 3 P00492 1 +Striatum development 0.3079454056346893 0.0949054211863898 0.9243899504746892 1.0 1.0 3 P00492 1 +Positive regulation of ruffle assembly 0.3010401188707303 0.0941089220993185 0.925022633028501 1.0 1.0 3 P07737,Q7L576 2 +Negative regulation of protein localization 0.2984298101493814 0.0936966072222809 0.92535016546661 1.0 1.0 48 O95429,Q9UMY4,Q6GQQ9,Q13438,Q9ULC3,Q10713,Q16850,Q96PU5 8 +Negative regulation of autophagosome assembly 0.2906389301634495 0.0931305172320514 0.9257998735398956 1.0 1.0 3 Q9H444,Q8WVM8 2 +Histone phosphorylation 0.2985252795498304 0.0928141575822619 0.9260512034387248 1.0 1.0 20 Q9Y4B6,O75844 2 +Diadenosine polyphosphate metabolic process 0.2829123328380409 0.0925516276810144 0.9262597742425478 1.0 1.0 3 P41250,Q15046 2 +Response to uv b 0.2752708683564897 0.092083973700562 0.9266313214819432 1.0 1.0 3 P43246 1 +Regulation of metal ion transport 0.3002948019802808 0.0920108636068414 0.9266894082981004 1.0 1.0 59 P05556,Q9UKS6,Q12959,P22466,P17931,Q06787,P27105,O95747,Q9Y376,Q07812,Q96PU5,P62942 12 +Histone arginine methylation 0.2632986627043113 0.0915247883000204 0.9270756106789776 1.0 1.0 3 O14744,Q99873 2 +Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.2615156017830633 0.0914569570837075 0.9271295061184728 1.0 1.0 3 Q9NWS0,Q99497 2 +Cellular response to vitamin 0.2553151908470245 0.0907554901391795 0.9276868777571708 1.0 1.0 5 Q15648 1 +Response to vitamin d 0.2536425810288519 0.0899101314787014 0.9283586300072316 1.0 1.0 5 Q15648,P20020,Q14258,O15164 4 +Purine nucleotide catabolic process 0.2807845341343512 0.0899098725586033 0.9283588357622554 1.0 1.0 11 Q9NRG1,Q9Y3Z3,O43598 3 +Deoxyribonucleoside monophosphate metabolic process 0.283615047863081 0.0898673666014471 0.9283926138702374 1.0 1.0 8 P00491,P27707,P04818,O43598 4 +Alpha beta t cell differentiation 0.2835951703564865 0.0898371520748244 0.9284166244547812 1.0 1.0 8 P00491,P35268,P09429 3 +Dna strand elongation 0.3000549052665878 0.0895044871328134 0.9286809876819836 1.0 1.0 22 Q9H1E3,P49005 2 +Regulation of dna directed dna polymerase activity 0.2851147361133559 0.0893272082414038 0.9288218714484844 1.0 1.0 9 Q8WVB6 1 +Cell substrate junction organization 0.302654935922466 0.0892165559891873 0.9289098080689568 1.0 1.0 31 Q9Y490,Q9P258,Q9H6U6,Q96AC1,O95819,Q9H2G2,P12814,P23229,Q14247,Q15555,P63000,P11047,Q9Y2Q5,Q7Z460,P51452,O75116,Q03001,P11274,O14786 19 +Mononuclear cell differentiation 0.2978143618297061 0.0891593035683625 0.9289553075686664 1.0 1.0 48 O15347,P05556,P01889,P78536,P04062,Q9BXW9,P09429,P17931,Q6IBW4,Q9Y4B6,Q04721,Q07812,P49768,Q15648,P55327 15 +S adenosylmethionine metabolic process 0.249479631281601 0.0879162215248313 0.9299432636153128 1.0 1.0 5 Q9NZL9,O43865,P23526,P31153 4 +Mesenchyme development 0.3002753550874126 0.0870070077710659 0.9306659418385634 1.0 1.0 40 P19022,Q53EL6,O00560,Q14118,Q9Y6N7,O14786 6 +Golgi disassembly 0.2403780139054898 0.0840749816134273 0.9329968159825388 1.0 1.0 5 P06493 1 +Postsynaptic cytoskeleton organization 0.2630044817800498 0.0836079608900448 0.93336813722642 1.0 1.0 6 Q9UJU6 1 +Developmental pigmentation 0.2817957131471336 0.0834479991989205 0.9334953237299132 1.0 1.0 9 Q07812,O75787 2 +Negative regulation of amyloid precursor protein catabolic process 0.2816847006199999 0.0832549105838726 0.9336488519112816 1.0 1.0 9 Q13526,P49755 2 +Regulation of muscle cell differentiation 0.2970697873567177 0.0814555250810659 0.9350796931379368 1.0 1.0 21 O75179,P67809,Q53EL6 3 +Regulation of rig i signaling pathway 0.2758928571428595 0.078635438653145 0.9373225988344775 1.0 1.0 8 Q07021,O75179,Q9NUD5,Q14671,Q8TAT6,Q9NZM5,Q92890 7 +Regulation of cytoplasmic transport 0.2865713724575166 0.0783440553148395 0.937554374057954 1.0 1.0 15 Q9Y3E7,P28482,Q9UMY4,Q02750,P15311,P36507,O60493,P26038 8 +Cell cycle dna replication 0.2961555543588041 0.077709549815818 0.9380590974262032 1.0 1.0 21 O75844 1 +Cellular response to nutrient 0.2537180249851177 0.0762845031366082 0.9391927546215396 1.0 1.0 6 P09601,O15164,P20020,Q96C86,Q15648 5 +Positive regulation of g1 s transition of mitotic cell cycle 0.2849793621570059 0.0736096691525437 0.941320977143164 1.0 1.0 15 Q8N122,P78536 2 +Positive regulation of protein kinase activity 0.2978842958456607 0.072989398654363 0.941814553657379 1.0 1.0 58 Q8N122,Q13177,P23396,P78536,P54619,Q12959,Q02750,Q9Y4G8,P07900,Q14118,Q9Y376,Q86Y37,Q9Y6N7,P49768,P08238,Q96A49,Q99828 17 +Cytoplasmic sequestering of protein 0.2747841619529562 0.0717025005387889 0.9428386661449244 1.0 1.0 9 Q9UN86,Q7L5D6,O75832,Q9UNN5,Q16643,O60826,P30626,P21333 8 +Ectoderm development 0.2453896490184327 0.0705923951331613 0.9437221631186454 1.0 1.0 6 Q8N1B4,P35240,P13693,P23229,P35222 5 +Cellular response to lipid 0.2962506034808459 0.070329279710446 0.9439315783607533 1.0 1.0 102 P09429,O15118,P01130,Q53EL6,Q13309,P26583,Q14118,Q8WTV0,O95831 9 +Membrane biogenesis 0.2975848421394741 0.0702200450016413 0.9440185201009808 1.0 1.0 26 Q9UQN3,Q9Y3E7,P19022,Q9H6H4,Q9UNZ2,O14976,O75955,Q9UNF0,Q86XL3 9 +Acidic amino acid transport 0.2834898987239059 0.0692374996617559 0.9448005743002136 1.0 1.0 15 P05556,Q9UPY5,P49768,Q8TDW0 4 +Ribosomal large subunit export from nucleus 0.2573638797976835 0.0671054269363085 0.946497773565962 1.0 1.0 7 Q99567,Q9NVU7,P62826,Q96D46,P06748,Q15050 6 +Protein import 0.2868026365070287 0.0661432424465182 0.9472637837138684 1.0 1.0 91 O75312,Q99595,Q06481,O60830,Q9ULC3,P13473,O60684,O00459,P49768,O95831 10 +Leukocyte homeostasis 0.2766091414518112 0.0653668195962819 0.9478819416854044 1.0 1.0 13 Q9UPY5,P78536,P09429,Q07812 4 +Dna ligation 0.2649714359366377 0.0644529215175495 0.948609592309508 1.0 1.0 8 P09429 1 +Cellular response to hormone stimulus 0.317056637189306 0.0644345469291894 0.9486242226983426 1.0 1.0 130 P42785,Q06481,O15118,O94813,Q9H1E3,Q13309,P67870,O00459,Q9UQB8,O95831,Q15043 11 +Amp biosynthetic process 0.2680715315974157 0.0639771573597149 0.9489884153244734 1.0 1.0 11 P07741 1 +Regulation of erad pathway 0.2537683658531678 0.0639187673652836 0.9490349086387472 1.0 1.0 7 Q04323,P54578,Q4ZIN3 3 +Establishment of mitotic spindle localization 0.2725861076147108 0.0635968872547459 0.949291210337536 1.0 1.0 12 P05556,P43034 2 +Neuron death in response to oxidative stress 0.2688300089312271 0.0624412912259797 0.9502114134510218 1.0 1.0 9 P35222,P09874,Q9UPY5,Q15233,P63244,Q99497,O75915,Q07820 8 +Receptor clustering 0.2767895377725151 0.0604650144092131 0.9517852793034808 1.0 1.0 14 P19022,Q14168,Q12959 3 +Positive regulation of reproductive process 0.2493305563820315 0.0602235440271458 0.9519775943227649 1.0 1.0 7 Q07021,Q9H6S0,Q99828,O14965,Q92769,P35222 6 +Protein localization to cytoskeleton 0.2913636114347986 0.0531341234540762 0.9576250432590808 1.0 1.0 22 Q9P2S5,Q15691,Q8IVD9,Q15154,Q13561,P78559,P29372 7 +Negative regulation of protein modification process 0.3230103678989459 0.0530363857128859 0.957702916890744 1.0 1.0 140 O60271,Q96KB5,P17931,Q12834,P18887,P62942,Q99828,P04792,Q07954,P60866,O00410,O95373,P49768,Q96B36,Q04323,Q6YHK3,O94992,O94813,Q32P28,O60678,Q13177,P10644,P04062,Q53EL6,P62913,O75718,Q01105,P23396 28 +Regulation of vasculature development 0.2968563171157783 0.052674551468202 0.957991215854694 1.0 1.0 36 O14786,P29317 2 +Regulation of striated muscle cell differentiation 0.2670704447627772 0.052050307854431 0.9584886078399726 1.0 1.0 12 P67809,Q9BYT8 2 +Muscle cell apoptotic process 0.2661115366600999 0.0501128811225726 0.9600324349846868 1.0 1.0 12 P98175,Q53EL6 2 +Negative regulation of protein tyrosine kinase activity 0.2507628487635411 0.0488659697593253 0.9610261086460614 1.0 1.0 8 P49768,Q9BRG1,Q9UNH7 3 +Midbody abscission 0.258310318391846 0.0464045376937932 0.962987819854382 1.0 1.0 11 Q9UQN3,Q9Y3E7,Q9H444,Q8WUX9 4 +Metal ion export 0.2270157691163365 0.0453270367437484 0.9638466373754102 1.0 1.0 7 P62258,Q12959,P05023,P20020,P54709,P23634 6 +Positive regulation of intracellular transport 0.2898085775465142 0.0445128136811897 0.9644956382608628 1.0 1.0 76 O75312,Q9NV96,Q9Y3D6,P55786,P15311,Q9H6U6,O00410,O14737,P27105,P06493,O00459,Q92688,Q15154,P49768,P08238,Q9C0E2,Q9H4M9,Q99828 18 +Pyrimidine containing compound biosynthetic process 0.2674306862673952 0.0441114042981958 0.9648156023189194 1.0 1.0 13 P17812,Q9NRF8,Q9BZX2 3 +Hormone transport 0.2953577349482432 0.0438682690825083 0.9650094085447118 1.0 1.0 36 P22466 1 +Negative regulation of protein metabolic process 0.3916770967835594 0.0437514898759561 0.9651024954965616 1.0 1.0 293 O60271,Q96PZ0,Q96KB5,Q06481,O94898,P01130,P78318,O00560,Q13526,Q12834,P61201,P05067,P18887,P62942,P04792,Q07954,P60866,P60520,P10619,Q96K76,Q92530,P49768,P08238,Q96B36,Q04323,Q6YHK3,O94992,Q9NQX7,Q9HBH5,O94813,Q86TB9,Q06787,Q92896,P67809,P06730,Q10713,Q32P28,O60678,Q15392,P78559,P10644,P06756,P05198,Q9C0C9,P04062,Q9UMY4,Q53EL6,P04080,Q14444,P62913,Q16850,Q7Z739,Q01105,P23396 54 +Positive regulation of catalytic activity 0.3685704926289016 0.0396169643118584 0.9683985024912318 1.0 1.0 223 Q8WVB6,Q9Y3D6,P54619,Q15185,Q9H6U6,Q13526,O14737,P26583,O75832,P84095,Q14118,Q12834,P05067,P18887,Q9Y6N7,Q9BXI6,Q99538,Q8TC07,P07602,Q4KMP7,Q96A49,Q99828,P05556,Q9BRT9,P78536,P61088,Q0IIM8,Q86X10,Q92688,Q07812,P49768,P08238,Q12959,Q92542,Q02750,Q9Y4G8,P07900,Q9Y376,Q13177,Q8WTV0,Q9NUM4,Q9NWS0,O95831,Q8N122,Q9NR28,P09429,Q9Y624,P46108,P46060,Q15375,P11274,P29317,Q86Y37,Q969S3,P23396 55 +Base excision repair gap filling 0.2513400833829636 0.0361544045234072 0.9711592421186096 1.0 1.0 10 P27695,Q9NX46,P12004,P18858,P39748,Q07864,Q96T60,P28340,P49916 9 +Negative regulation of organelle assembly 0.2047009818506419 0.0356795903489952 0.9715378447307972 1.0 1.0 7 Q9H444,P50570,Q8WVM8,P50395,O75396,P27816 6 +Mrna methylation 0.2016457564663577 0.0346954183202347 0.9723226143802748 1.0 1.0 7 Q08J23 1 +Regulation of intracellular signal transduction 0.3916405837875985 0.0337829754075429 0.9730502118531988 1.0 1.0 297 Q9Y3D6,Q07960,P19525,P05067,P02786,Q92905,Q99828,O75787,Q07812,Q12959,P63096,Q02750,O94813,O75955,Q13641,P07900,P52565,Q99956,Q9NWS0,P06756,P04062,Q13418,O14744,O43657,Q9Y624,P29692,Q15375,O75844,P29317,O14786,O00170,Q9Y6N7,P05556,O94992,P19022,Q9Y4G8,Q86VI3,Q10713,O00459,Q8N122,P09429,Q53EL6,Q92734,P23396,Q9UMX5,Q6GQQ9,P78318,O00560,Q13526,Q14118,Q9Y6K9,P62942,P16949,O75179,Q86X10,P49768,Q96B36,O95429,P63241,P13693,P29372,Q7Z7H5,P62913,P43034,O60271,Q96KB5,P62993,P04792,P61088,P60866,Q9H0H5,Q96K76,Q04721,P08238,Q13177,Q96J02,Q9BW85,P46108,Q15382,Q969S3 80 +Regulation of apoptotic signaling pathway 0.2908056101028851 0.0313963639751433 0.9749534408509042 1.0 1.0 100 Q9Y3D6,Q9NQX7,Q14247,P23396,P04792,Q13177,P17931,P26583,P63241,P13693,Q96K76,Q07812,P49768,P53634,O14786,P06756 16 +Regulation of establishment or maintenance of cell polarity 0.2421043475878324 0.028639037177182 0.9771524776779216 1.0 1.0 9 A0MZ66,Q9H6U6 2 +Positive regulation of nucleocytoplasmic transport 0.2911202696304231 0.0275261361344922 0.9780400941215616 1.0 1.0 31 O75312,O00410,P06493,O00459,Q92688,P49768,P08238,Q9C0E2 8 +Myeloid cell homeostasis 0.2881914733255194 0.0267224107769165 0.9786811382983682 1.0 1.0 46 O00115,P26583,Q92542,P09429 4 +Nucleobase biosynthetic process 0.2701018242392305 0.0223002441186934 0.9822084541530376 1.0 1.0 16 Q9NRG1,Q9NRF8,P07741,P00492,P17812 5 +Dna methylation 0.2773508381675833 0.0213790012873664 0.9829433242828444 1.0 1.0 19 Q8NB78,O75844 2 +Nuclear membrane organization 0.2857347569058218 0.0212970961884979 0.9830086602208424 1.0 1.0 24 Q9UQN3,Q9H6H4,Q9Y3E7,Q9H444,Q9UNZ2,P43034,Q86XL3,Q14203 8 +Smooth muscle contraction 0.2394282310899294 0.0212792807356225 0.9830228716750472 1.0 1.0 10 Q14247,Q12959,P52306,Q13464,O00213,P20020,O75116,P23634,Q86TU7 9 +Cortical cytoskeleton organization 0.2870403146965823 0.0206146082263181 0.9835530872631572 1.0 1.0 28 Q12959,P15311,P43034,P84095,Q9H0H5,Q14651,Q5VSL9 7 +Mismatch repair 0.2559322987248443 0.0203093587539732 0.98379659012161 1.0 1.0 13 P09429,P18858,P43246,Q9UQ84,P52701 5 +Mitotic cell cycle phase transition 0.3081792919990126 0.018754897344725 0.9850366341921232 1.0 1.0 124 P05556,Q8N122,O75312,P78536,Q06481,P08183,O75179,Q13309,Q86VI3,Q9Y619,P05067,Q86Y37,Q13564,P49321 14 +Regulation of cell matrix adhesion 0.2862069377837827 0.0165597894386833 0.9867878035354982 1.0 1.0 27 Q9H2G2,Q9H6U6,Q14118,P42771,O14786,Q99828 6 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.2625093166547602 0.0136680417602358 0.989094820046686 1.0 1.0 15 Q15118,Q9NR28,P04792 3 +Negative regulation of cellular catabolic process 0.287192255594178 0.0114029140821021 0.9909019880698546 1.0 1.0 98 Q96KB5,O94898,O15118,P62913,P60520,O00560,Q9H814,Q06787,P10619,P67809,Q92530,P49768,P08238,P78559,Q08J23,Q04323 16 +Specification of symmetry 0.2205854879487627 0.009874916030021 0.9921210850113384 1.0 1.0 9 P49768 1 +Face development 0.1778852142590348 0.0093686228007728 0.9925250298591544 1.0 1.0 8 Q02750,P28482,P27361,Q06124 4 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.1708333333333358 0.0080504293086221 0.9935767561280002 1.0 1.0 8 O60885,P55199,O14776,Q9Y5B9,Q7KZ85,P35269,P35222 7 +Escrt complex disassembly 0.1636904761904785 0.0069810629055394 0.9944299629325616 1.0 1.0 8 Q9UQN3,Q9UN37,Q9NP79,Q9HD42,Q9NZZ3,Q8WUX9,P53990 7 +Positive regulation of lamellipodium assembly 0.2383790226460077 0.0029150284225727 0.9976741471212748 1.0 1.0 12 Q16658,P60953,P50570,P63000,P61160,O15144,Q9Y6W5,Q9Y2A7,Q6IBS0,Q7L576,P42345 11 +Negative regulation of peptidyl tyrosine phosphorylation 0.226454029623657 0.0026404869807973 0.9978931986531844 1.0 1.0 11 Q99816,Q9BRG1,Q8WXW3,P49768,Q9UNH7 5 +Regulation of protein targeting 0.2828452381095843 0.0007695278115926 0.9993860057006204 1.0 1.0 28 P27105 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d4cdb21d7cabcf17caa03bed056c43b1b837a669 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cholesterol", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Dipeptide transmembrane transport", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic camera type eye morphogenesis", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic eye morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens fiber cell morphogenesis", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphatic endothelial cell differentiation", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Midbrain hindbrain boundary development", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Notochord development", "Notochord morphogenesis", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide import across plasma membrane", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of bicellular tight junction assembly", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chondrocyte proliferation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of corticosteroid hormone secretion", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of hair follicle maturation", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell population maintenance", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid hormone secretion", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart morphogenesis", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of resting membrane potential", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to inactivity", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle inactivity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to stimulus involved in regulation of muscle adaptation", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC10", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD5", "C2orf49", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC93", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPF", "CENPI", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG2", "COG4", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD3", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GID4", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFB", "NELFCD", "NEMF", "NENF", "NEO1", "NES", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NGDN", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PAXBP1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TATDN1", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGGT2", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP73", "WRNIP1", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB33", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAK1", "AAMP", "AARS", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCE1", "ABCF3", "ABHD12", "ACIN1", "ACP1", "ACP2", "ACTN1", "ACTN4", "ACTR2", "ADAM17", "ADD1", "ADD3", "ADGRE5", "ADK", "ADPRHL2", "ADSL", "ADSS", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AIP", "AKAP12", "AKR1A1", "AKT1S1", "ALCAM", "ALDOA", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "AP1G1", "AP1M1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APLP2", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGAP1", "ARHGDIA", "ARIH1", "ARL3", "ARL6IP5", "ARMT1", "ARPC1B", "ARPC2", "ASAH1", "ASCC2", "ATF7IP", "ATG3", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATXN2", "AURKA", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BAX", "BCAP29", "BCAP31", "BCAS3", "BCCIP", "BCR", "BICD2", "BLM", "BRD2", "BRD4", "BSG", "BTAF1", "BTF3", "BUB1B", "C1QBP", "C2orf49", "CAB39", "CACUL1", "CALCOCO2", "CALD1", "CAND1", "CAP1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CASP8", "CBL", "CCDC22", "CCDC94", "CCT4", "CCT7", "CD109", "CD2AP", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CEP290", "CERS2", "CETN2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAMP1", "CHEK2", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHTF18", "CIB1", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLTA", "CLTC", "CNN3", "CNNM3", "CNNM4", "COG2", "COLEC12", "COPB2", "COPG1", "COPS2", "COPS3", "COPS5", "COPS6", "COPS7B", "CORO1C", "COTL1", "CPD", "CPVL", "CRK", "CRKL", "CRTAP", "CSDE1", "CSK", "CSNK2B", "CSRP2", "CSTB", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL2", "CUL3", "CXADR", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DAG1", "DAGLB", "DBN1", "DBNL", "DCAF1", "DCK", "DCPS", "DCTN1", "DCTN2", "DCTPP1", "DDA1", "DDRGK1", "DDT", "DEGS1", "DEK", "DENR", "DHCR24", "DHCR7", "DHRS7B", "DIABLO", "DIAPH3", "DICER1", "DLG1", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC2", "DNAJC3", "DNAJC7", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK6", "DOHH", "DPH2", "DPH5", "DSC2", "DSC3", "DSG2", "DST", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DYNC1I2", "DYNC2H1", "DYNLL1", "DYNLL2", "ECE1", "EDC3", "EDC4", "EEA1", "EEF1B2", "EEF1D", "EEF1G", "EEFSEC", "EFL1", "EHD1", "EHD4", "EIF2AK2", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF3H", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4H", "EIF5", "EIF5A", "ELL", "ELMO2", "EMB", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPS15", "ERBIN", "ERCC2", "ERMP1", "ETF1", "EXO1", "EXOC3", "EXOC6", "EXOC7", "EZR", "F11R", "FAF1", "FAM129B", "FAM3C", "FANCD2", "FASN", "FAT1", "FBXO22", "FCGRT", "FEN1", "FERMT2", "FIS1", "FKBP1A", "FKBP4", "FKBP9", "FLII", "FLNA", "FLOT1", "FLOT2", "FMR1", "FSCN1", "FTL", "FUCA1", "FUCA2", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GAL", "GALNT1", "GARS", "GART", "GBA", "GCLC", "GCLM", "GDI2", "GET4", "GFPT1", "GGH", "GGT7", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLG1", "GM2A", "GMFB", "GMPS", "GNA11", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA5", "GOLPH3", "GOT1", "GPAA1", "GPHN", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTF2F1", "GTF2H1", "GTPBP1", "HAT1", "HAUS5", "HAUS6", "HAX1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HECTD1", "HEXA", "HEXB", "HEXIM1", "HGS", "HIP1", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HNRNPD", "HOOK2", "HPRT1", "HPS6", "HS2ST1", "HSP90AA1", "HSP90AB1", "HSPA13", "HSPA1B", "HSPA2", "HSPA8", "HSPB1", "HTATSF1", "HTT", "ICMT", "IDH1", "IFT52", "IGBP1", "IGF2R", "IKBKG", "ILK", "ILKAP", "IMPAD1", "IPO4", "IPO5", "IPO7", "IPO9", "IQGAP1", "IQGAP3", "IST1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "IWS1", "KARS", "KDELR3", "KDM1B", "KIF14", "KIF1A", "KIF5B", "KIF7", "KLC1", "KPNA1", "KPNA2", "KPNA6", "KPNB1", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR2", "LARP1", "LARS", "LBR", "LDHA", "LDHB", "LDLR", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LNPEP", "LPCAT2", "LRIG2", "LRP1", "LRRC8C", "LRSAM1", "LSM3", "LTA4H", "M6PR", "MAN1A2", "MAN2B1", "MAN2B2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKSL1", "MARS", "MASTL", "MAT2A", "MAT2B", "MCAM", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MED1", "MED4", "METTL13", "MFGE8", "MIA3", "MICALL1", "MID1", "MIF", "MIF4GD", "MINDY3", "MPG", "MPP2", "MRC2", "MSH2", "MSH6", "MSN", "MSTO1", "MTAP", "MTFP1", "MTHFD1", "MTMR14", "MTOR", "MTPN", "MTR", "MYG1", "MYH10", "MYH9", "MYO5A", "NAA10", "NAA25", "NAA40", "NAA50", "NAE1", "NAF1", "NAGLU", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NCAM1", "NCAPD2", "NCAPG", "NCAPH", "NCAPH2", "NCDN", "NCKAP1", "NCL", "NCSTN", "NDUFA2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEMF", "NENF", "NEO1", "NES", "NF2", "NFATC2IP", "NISCH", "NLN", "NMD3", "NME1", "NNT", "NONO", "NOP53", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRDC", "NRP1", "NSD2", "NSFL1C", "NSUN2", "NSUN5", "NTMT1", "NUB1", "NUCB1", "NUCB2", "NUCKS1", "NUDCD3", "NUP88", "NUTF2", "OCRL", "OS9", "OTUB1", "OTUD7B", "OXSR1", "P3H1", "P3H4", "P4HA1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAICS", "PAK2", "PALD1", "PANX1", "PAPSS1", "PARK7", "PARP1", "PARP2", "PATL1", "PBK", "PCDH7", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCD5", "PDCD6IP", "PDCL3", "PDE6D", "PDK1", "PELO", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGLS", "PGM3", "PGP", "PHAX", "PIBF1", "PICALM", "PIH1D1", "PIK3R2", "PIN1", "PIR", "PITHD1", "PKM", "PKN1", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLIN3", "PLK1", "PLS1", "PLXNA1", "PMPCA", "PMVK", "PNKP", "PNP", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLE", "POLR3C", "PPAT", "PPIL1", "PPIL2", "PPM1G", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPT1", "PPT2", "PRCP", "PRDX2", "PRELID1", "PREPL", "PRIM1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRMT1", "PRMT3", "PRMT5", "PRPSAP1", "PRPSAP2", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSMA1", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC5", "PSMC6", "PSMD10", "PSMF1", "PSMG1", "PSMG3", "PTGES3", "PTK7", "PTPA", 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"SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIT2", "SLK", "SMAP1", "SMARCAD1", "SMC4", "SMG8", "SNAPIN", "SNU13", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX4", "SNX6", "SORT1", "SPAG9", "SPART", "SPATA5", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN2", "SPTLC1", "SRI", "SRP19", "SRP9", "SRPK1", "SRSF6", "SSRP1", "STARD3NL", "STK26", "STK3", "STMN1", "STOM", "STRIP1", "STUB1", "STX12", "STX17", "STX4", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SV2A", "SYAP1", "SYNGR2", "TALDO1", "TAP2", "TAX1BP1", "TBC1D10A", "TBC1D10B", "TBC1D15", "TBC1D8B", "TBC1D9B", "TBCD", "TCERG1", "TCP1", "TDRKH", "TELO2", "TENM3", "TFG", "TFRC", "TGFBRAP1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIPRL", "TJP1", "TKT", "TLN1", "TM9SF3", "TMED10", "TMED4", "TMEM106B", "TMEM165", "TMEM230", "TMEM259", "TMEM30A", "TMEM87A", "TMEM97", "TMOD3", "TOMM22", "TOMM5", "TOR1A", "TP53BP2", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPT1", "TRA2B", "TRIM24", "TRIM25", 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1.943624711824081e-05 5.728479637947586e-06 0.0005914326993413 +Exocytic vesicle 7 45 3.161367494342104 0.0015703024518374 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.004957270143675 0.1433250213961272 0.0021556450586784 0.0182716334744495 0.0679677969765625 +Recycling endosome 15 45 3.134072581264707 0.0017239820741379 11.66504854368932 38.48300970873787 0.3314123370484901 0.5655153978404952 4.733627044629046 5.712973030267684 1.060328776827888 0.3489425897551162 0.0303800632075801 0.0339635306200824 0.0029716947576053 0.0002201580608466 0.0006770737867445 +Apical part of cell 13 69 3.1331866192522253 0.001729194606389 15.599514563106796 57.72330097087379 0.5629683512109013 0.5412025823450395 6.485031290002554 7.326381428218615 1.086566128273008 0.3654459232984969 0.0054351625538253 0.0027380535511036 0.0131111774231964 0.0003496086582639 0.0036569184700586 +Early endosome membrane 18 52 3.103234435654353 0.0019141794235473 12.29611650485437 44.95873786407767 0.5277524243262064 0.5849546522697281 4.982462882428341 7.094079738701261 0.90392558948614 0.3412735259006035 0.0801516167184463 0.1234363306283571 0.0073683848156872 4.877907376628178e-05 2.0791314186223096e-06 +Clathrin coated vesicle membrane 5 24 3.090160367949338 0.0020004844987742 5.987864077669903 23.8373786407767 -0.1745074444216576 0.5217181929114124 3.796056755917445 2.6366094957976225 1.1352900407304896 0.3325344982200064 0.0001317221920365 1.1178795131295548e-05 0.000316040607354 0.0036079185825643 0.0091218528537202 +Membrane microdomain 18 73 3.0781725454204016 0.0020827428462315 14.75485436893204 63.49029126213592 0.5762129399877682 0.5023556315347317 6.545256989336744 6.436953608643344 1.167657055169838 0.3823949317010994 0.0208137962642245 0.0148017620517202 0.0119471469282636 0.0009362812812023 0.0012330738614807 +Ficolin 1 rich granule 17 86 3.068225220438596 0.0021533426047302 23.65776699029126 87.40776699029126 -0.2227524879803391 0.5328920793977936 13.237445521916472 3.951617324550425 1.218029306074882 0.3604375114796861 0.0001259462753318 0.029947979425984 0.0004013521153891 0.0020179972297504 3.828337334630684e-05 +Clathrin coated endocytic vesicle 5 19 3.064177963183156 0.0021826902698618 4.774271844660194 18.74271844660194 -0.0983362729934113 0.4816370533307881 3.136849294900222 2.1033538609603957 1.2416005860349415 0.3436375292109884 2.9952004208242496e-05 2.4350782386469327e-06 7.346424910355626e-05 0.0007319888819485 0.0056815658241212 +Clathrin coated endocytic vesicle membrane 5 15 3.0390742986573858 0.0023730632095646 3.796116504854369 13.682038834951456 0.0573666642471241 0.400612365903674 2.3816010903207343 1.646817383208435 1.3652035545006669 0.3297171871883064 8.482422014919752e-06 6.712990966849457e-07 2.109493408887589e-05 0.0001788568995486 0.0063226090272968 +Endosome membrane 43 142 3.01409567531466 0.0025774650993424 28.436893203883496 125.75485436893204 0.1968108610887141 0.5657595498250074 10.058247741499075 16.477863960688197 1.2734596099850304 0.3756178998455078 1.1377870883978222e-09 1.770836345918081e-06 8.697055356419216e-11 4.6174836077561625e-11 9.927453092108696e-09 +Distal axon 26 65 2.9740546955824847 0.0029389268373123 14.37621359223301 56.932038834951456 0.087742779329781 0.64290004839216 6.757715276645177 6.171516368750388 0.8600493637808696 0.3236313299944118 0.0488138100840459 0.2008803863342955 0.0251503259597814 0.120015657708121 0.1225649222275473 +Azurophil granule membrane 9 23 2.966326241868348 0.003013806062768 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 7.590182605273208e-08 0.0014522342124754 2.763713046248423e-07 1.1854087112688965e-07 9.320882398318224e-06 +Tertiary granule 13 41 2.9495260938499284 0.0031826169616204 10.41504854368932 41.036407766990294 -0.0889487004392956 0.5196752089107607 4.251221040765739 3.0949590565759384 1.1107953602779526 0.3305399634314611 9.891562096249526e-05 0.0746572323120207 0.000276347734322 0.0003973845514903 0.0001348606328423 +Clathrin coated pit 4 25 2.945600285286468 0.0032232863962569 6.813106796116505 23.92233009708738 -0.3634603746412232 0.5290548253531329 3.4198908541960824 3.6938398480544263 1.0001526474813611 0.326415656204558 9.509760184517996e-05 7.984541534446868e-06 0.0002294243633388 0.0124412460735711 0.0200998155918958 +Secretory granule 52 248 2.9371301051505982 0.0033126509371803 49.29854368932039 231.6504854368932 0.0742534337219474 0.6450440279734955 14.609170474630965 16.529443419678444 1.2643241567239918 0.3828342632667716 1.2843174766676268e-21 4.8270652043415886e-11 6.7733752665849475e-22 4.2141155805398095e-18 3.048199121219379e-18 +Golgi associated vesicle 7 32 2.915738592097408 0.0035484767371942 6.745145631067961 30.33009708737864 0.696501539533066 0.3869218626415568 3.3093865809086713 3.3403631844705557 1.2881306559419168 0.3350067162782171 0.0002207581084483 0.0003307976495693 5.125472236765286e-05 0.0002356945742808 0.0054856561315088 +Secretory vesicle 55 275 2.8997846616763554 0.0037341910180854 56.25485436893204 257.47087378640776 0.1341228551105892 0.6386901443364594 16.601865631745117 19.12774191814033 1.3029114519128766 0.3900514633935764 2.665149975206763e-20 8.502380273970039e-11 2.472509157097845e-21 6.576456939672317e-17 4.85798763325347e-16 +Basal part of cell 12 53 2.840852030411344 0.0044993183585784 12.87378640776699 49.39563106796116 0.4231791430151931 0.5418083225496748 6.317535484281435 5.887808725837185 1.1575518486276402 0.3620095959132046 0.0271700272219672 0.0048088141850313 0.0486349844586409 0.0001581648012048 0.0033547161428921 +Site of polarized growth 21 56 2.7913160122611766 0.0052494192676371 12.407766990291265 48.44417475728155 0.0465719733262774 0.6407527041886554 6.134712459065642 5.7567427791912475 0.8677611137018515 0.3206519581677468 0.2858612796269977 0.1332928413805449 0.1352776549759777 0.2121066412096609 0.0523560798520111 +Endosome 50 233 2.768098168122796 0.0056384469025141 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 1.3071040168322916e-11 1.502541685951366e-09 7.405023651309469e-12 3.870965974379644e-13 4.310828363088051e-09 +Basolateral plasma membrane 11 47 2.741213471606716 0.0061212723512953 11.907766990291265 41.713592233009706 0.4173504135492652 0.5464661760255546 5.696723454799589 5.533263026209871 1.098008793343998 0.3512755123780914 0.0671474226148655 0.0186549140563941 0.1033422929764065 0.000111900171939 0.0013674597922856 +Trans golgi network transport vesicle 2 13 2.7339709860633685 0.0062575558096236 4.007281553398058 12.91019417475728 -0.165056273529708 0.5953281491980702 2.4210736181324606 1.5961704659812874 0.9219447964283688 0.3231276900084591 0.0014713217280779 0.0003334624710947 0.002509898486982 0.0300655360870906 0.0451666412494461 +Phagocytic vesicle 9 46 2.7320057431631155 0.0062950043643779 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 0.0088607173186997 0.086158736226278 5.368000360583747e-05 0.0001584508875138 0.0235992313294809 +Collagen containing extracellular matrix 10 33 2.729915370101815 0.006335058617753 7.388349514563107 28.936893203883496 0.1094979606259816 0.5901779878192949 3.847790968094583 3.6231320005554526 0.9701213079318116 0.3238613597958452 0.0271700272219672 0.1501018175915273 0.0486349844586409 0.0022446099415609 0.040500073124584 +Late endosome 27 77 2.729380299124509 0.0063453480716764 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 7.556787670162523e-07 5.751585031261305e-05 7.04297716189301e-07 2.6227256514781772e-08 6.868714844635943e-07 +Lumenal side of membrane 4 10 2.6851170064705694 0.0072504418793708 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.0136086826932428 0.1026081339138497 5.563842498563775e-05 0.0001563365146727 0.0004973671187583 +Presynapse 14 98 2.594857085782424 0.0094630257793644 22.813106796116504 90.997572815534 0.4365135448276876 0.6534842370695999 7.919284748658944 8.50627945845188 0.826940228235506 0.3445781590237917 0.027575193700247 0.4061443456431609 0.0210641995738519 0.0867724217460314 0.2191859508649919 +Apical plasma membrane 21 52 2.588529605336081 0.0096386661204581 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 0.137749763153836 0.1813311010194401 0.2022112376683019 0.001685736666845 0.0220872867336108 +Neuromuscular junction 8 23 2.5757263649595936 0.0100029773257974 4.62621359223301 16.633495145631066 0.4855035135155566 0.54061233402628 2.386469186408936 2.9236472131013795 0.8090611388618595 0.3124321260069755 0.2968609783283818 0.1908924307699622 0.0663348012473392 7.239536568685886e-05 0.0001845554743826 +Platelet alpha granule 6 19 2.573311732320076 0.0100730433700875 4.211165048543689 15.902912621359222 0.6039612674990132 0.4510107266729922 2.510477385063311 2.1030009215071965 0.8798256715017497 0.2887985186703408 0.0047509494145314 0.0179094063189584 0.00796664232011 0.0033942963153933 0.0038296417177728 +Vesicle membrane 60 279 2.5605154791977824 0.0104517007295625 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 6.422232071431063e-13 6.3879311097621e-08 4.517157543695894e-17 1.9498879591358798e-16 5.78783662393426e-10 +Phagocytic vesicle membrane 7 28 2.539223819185992 0.0111098723238096 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.0133377930203514 0.0358926009784828 0.000316040607354 0.0001087627785303 0.0091218528537202 +Blood microparticle 6 18 2.5085544191180817 0.0121226293739364 4.735436893203883 17.08252427184466 0.278306270999014 0.48728609275096 2.8336409309630577 1.4740425350178823 1.0421411126986748 0.31816279579515 0.0456983473100118 0.0179094063189584 0.0636449972198752 0.0033942963153933 0.0038296417177728 +Cell body 35 115 2.491232970378141 0.0127300617491454 23.62135922330097 100.2135922330097 -0.2261944565190333 0.6872969325098738 10.154024028815115 9.144365855634126 0.6450340442422253 0.288113363632936 0.4455646517279858 0.1828350446371612 0.3417789266009901 0.0158040830434131 0.0003452605191492 +Golgi membrane 31 142 2.4728999653722465 0.0134021651550899 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.0574227149104675 0.1541980220314314 0.0029092633848811 4.901212416284692e-06 0.000206710540342 +Golgi apparatus subcompartment 16 98 2.455526538017668 0.0140678365297395 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0714703700993311 0.0442732258868589 0.0515740304713025 0.0003769878665062 0.0141335756318235 +Lumenal side of endoplasmic reticulum membrane 3 8 2.441267697260543 0.0146358011524876 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 0.1369226886862704 1.0 0.0006712136127385 0.0008110696558398 0.0013613651941044 +Ficolin 1 rich granule membrane 4 18 2.417082734447505 0.0156454605421603 4.395631067961165 17.803398058252426 0.1552184768165 0.4321380562295095 2.362999644561935 1.270535437467333 1.1498286388022771 0.2935073244440836 0.000139572011172 0.0112943240362007 0.0002865257018003 0.0011317572349641 0.0206839034685982 +Recycling endosome membrane 9 25 2.4119564983289674 0.0158671745759808 6.888349514563107 22.509708737864077 0.1536767921278238 0.6101735952601732 3.1901182670006487 3.1100218387491214 0.9055004805495972 0.3161343906862945 0.4550401045993952 0.3058671484100957 0.0359624367366125 0.0021288846429902 0.0029972169690089 +Ficolin 1 rich granule lumen 21 68 2.301890258022622 0.0213413617428992 21.924757281553397 69.60436893203884 -0.321023421032656 0.5390049696806432 12.227482521949598 3.2622108680133315 1.2098876727829837 0.3651506684866024 0.0539615299706925 0.4047844567784328 0.0839971460237413 0.1140446999459364 0.0005498781417767 +Tertiary granule lumen 5 15 2.287986804043557 0.0221382896012714 5.080097087378641 15.28640776699029 -0.3079983292417204 0.4707564584893597 2.953670086665961 1.2697028582661334 0.9645881412270784 0.2886719366464021 0.0277307016086551 1.0 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0.0438235854673598 +Anchored component of membrane 1 11 2.2303054020784123 0.0257271747953513 3.3228155339805827 7.995145631067961 0.0592794757206457 0.674664582231117 2.351443232708776 1.556376089571428 0.6691813332846253 0.2714844618790992 0.3195763160296334 1.0 0.3714211816154574 0.3191889313297822 0.6752060489618263 +Nuclear envelope lumen 1 5 2.2264790997191923 0.0259821074036357 1.5922330097087378 4.730582524271845 0.2740214243637495 0.4274662744917171 1.0138544466097483 0.5098416377826835 1.1584731829510644 0.3162624936844113 0.0009614964335136 0.0003491251705821 0.0013923625346842 0.0083506419453669 0.002061539822863 +Lamellipodium 19 66 2.174546206572796 0.029664139214282 16.150485436893202 61.599514563106794 -0.240986979460855 0.6581124942552721 8.153364589743493 6.544641308844849 0.7391517842443676 0.3013994617805701 0.4269120951888039 0.2170623616565413 0.2539407109248274 0.1455662085022431 0.3685130798038171 +Ruffle membrane 7 29 2.1710561735012446 0.02992692639909 8.21359223300971 27.68446601941747 -0.3210671894977177 0.600558186056877 4.051609977100661 3.33740953207239 0.7850019161194813 0.2974283996284634 0.1298049423458981 0.3161039234082394 0.0397455353834247 0.0398082827338284 0.0333177078736064 +Golgi lumen 3 6 2.1693833415651724 0.0300535926170018 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.0277307016086551 0.1457663642848915 0.0390334649397651 0.0424141111811751 0.0682397501835214 +Autophagosome 6 33 2.1657484159655644 0.0303304171044309 7.490291262135922 28.23058252427185 0.2382857558920592 0.551676712271876 3.4770262532301657 5.388565442188036 0.9533210099421008 0.3228297396792804 0.0400016925321865 0.3682511930157578 0.0631321797954323 0.0770567400392524 0.1675071972901493 +Platelet alpha granule lumen 3 11 2.149827635760942 0.0315688513343419 3.094660194174758 11.072815533980584 0.6725356672918105 0.3876488961533653 1.8442433739601936 1.3309383633877778 0.9473857774935364 0.2732835416220931 0.191665926491972 0.1201219647894398 0.2263045436956677 0.1318172807011351 0.0355737118947821 +Sarcolemma 8 28 2.134530359877119 0.0327993911850421 6.849514563106796 24.82766990291262 0.1401032497752024 0.6240915375619693 3.1177030936067345 2.404871957871013 0.82647351967221 0.3084890241561867 0.1083889445522632 1.0 0.1468141932972727 0.0014147813856964 0.0060441570275233 +Axon 41 140 2.088694091050677 0.0367352691108628 28.50485436893204 123.48300970873788 -0.1480614837947368 0.66370704402985 11.910975428503043 14.062178243823778 0.8082077724464304 0.3284972271669918 0.2113762162507096 0.299072375232168 0.1837966359480682 0.0295877547234026 0.0414094957955509 +Platelet alpha granule membrane 2 5 2.079962514239614 0.0375289712785522 0.8025316455696202 2.081012658227848 0.2614281433644114 0.3504902455917955 0.7607415908085344 1.052312215951031 1.6089664801163488 0.3217900283945228 0.0040983965897468 0.0573151884822011 0.0058956460302812 0.0026887292270871 0.0182159139614431 +Proteasome core complex 8 15 2.06666936439122 0.038765319801445 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 1.0 1.0 1.0 0.0006430769062578 4.962609141310809e-07 +Intrinsic component of presynaptic membrane 2 6 2.0575237286880443 0.0396358748283738 2.1529126213592233 4.754854368932039 0.3133963453989226 0.4445007611399023 1.2803277273621594 0.9007013061327611 1.0351014517698869 0.3027308229331067 0.1715513885376269 1.0 0.2030300441679912 0.1075130907868997 0.09905667817091 +Trans golgi network 10 72 2.057203061808657 0.0396666971580417 15.419902912621358 63.34466019417476 0.3899535194812628 0.596168565313415 5.947659406670704 9.796108085479462 0.9254595120691144 0.3511819564605877 0.2161299581540008 0.0719063758680329 0.3046519049461358 0.0089567999164934 0.1007531640241738 +Dendritic shaft 4 9 2.0543205062456247 0.0399446812908701 1.2402912621359223 5.310679611650485 0.894315195377243 0.3713817419556685 0.9794132940711298 1.209020515164722 0.8832746734598869 0.2869302240585097 0.1439609493286736 0.0892490045576324 0.1709159600444602 0.3751137360333714 0.0017743753624758 +Desmosome 2 8 2.028938168156111 0.0424645885483898 3.3106796116504853 6.434466019417476 -0.9067356401145186 0.322772712277776 1.496138240676771 0.8579024184165305 1.1482508166012304 0.3043884185116927 0.0092050279194046 0.0847528009868792 0.0131546828557762 0.0089509329804495 0.0544656750173612 +Multivesicular body 8 15 2.0197249291366486 0.0434119277809246 3.7742718446601944 12.094660194174756 0.0270444117783637 0.5442226252774409 2.4800207883335372 2.61498122866677 0.9464580912617488 0.3033802150556732 0.2852239797067621 1.0 0.3329579057594876 0.0778634639331788 0.0137025132522295 +Glial cell projection 3 5 1.9932308630386315 0.0462361730189697 1.4271844660194175 4.439320388349515 0.5256630412856145 0.4795278875555782 1.093688350806908 0.8638969757615467 0.9368809323777078 0.3221784257132529 0.1154630790463651 0.0711332726649859 0.1375212864755611 0.0506052248933858 0.0049531384619904 +Perinuclear region of cytoplasm 59 208 1.987340458590278 0.0468846810345273 41.351941747572816 185.873786407767 0.188099869779145 0.7574745839917925 13.945452720131469 19.27429981182019 0.8259268596181808 0.3356085544002479 0.0001907668011683 0.000650700111479 0.0011965688516775 9.364143880537506e-05 0.000103569818411 +Golgi cisterna membrane 4 16 1.986041099134672 0.047028760562515 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0668350320040178 0.2260688267312995 0.0921147949975289 0.0085171031160944 0.0397377338982377 +Transport vesicle membrane 6 44 1.9817328971850845 0.0475091432356773 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 1.0 1.0 0.1330503697063572 0.0386005660961293 0.2932126486911236 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ae52ae54cd0d233c65360437732c38b38a1c66cd --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 915, + "title": "Average number of proteins per term", + "value": 30.387978142076502 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2e97c5a291b7d6a1777f99fe539ae63cb8894740 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..58e1f9c5ef47f62b3b40152c12f9c33e2486bc4c --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,348 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Vacuolar lumen 0.9199178994323312 4.901993664803547 9.486889661458826e-07 0.000867674168661 0.0008680504040243 65 Q8NHP8,O14773,P15586,O00584,P61916,P06280,Q9UMR5,Q9BTY2,P50897,Q99538,P07602,P06865,Q14108,P04066,P54802,Q8IV08,Q9UM22,P13473,P10619,P10253,O00754,P16278,P17900,P53634,Q92820,Q9Y2E5,P11117,Q13510,P02792,P07686,P38571 31 +Cell surface 0.7573417449509495 4.446253053780196 8.73810094259575e-06 0.0079635191219993 0.0026668806184718 95 P55899,P42892,Q14126,P13591,P01130,Q92859,Q14118,P05067,P11717,Q9Y6N7,P02786,P05556,Q99523,Q13685,P08183,Q13740,Q6YHK3,P19022,P11279,Q08431,Q13641,P51790,O43847,P04439,Q8WTV0,Q08722,P43121,P06756,P01889,P09429,Q92692,P29317,P10321,P08195 34 +Azurophil granule 0.8353177524166552 4.446111176135338 8.743870880234539e-06 0.007968756603551 0.0026668806184718 68 P15586,O00584,P61916,P06280,Q9BTY2,P07602,P06865,P04066,P42785,P13473,P10619,P10253,O00754,P16278,P17900,P53634,Q92820,Q9NQX7,Q92542,P11279,P02792,P07686,P27105 23 +Lysosomal lumen 0.9630000003376642 4.274727417525943 1.9137128054680375e-05 0.0173582194261582 0.0043776180425083 36 Q8NHP8,O14773,P15586,O00584,P61916,P06280,Q9UMR5,P50897,Q99538,P07602,P06865,Q14108,P04066,P54802,Q8IV08,Q9UM22,P13473,P10619,P10253,O00754,P16278,P17900,Q9Y2E5,P11117,Q13510,P07686,P38571 27 +Side of membrane 0.7395065783767959 4.220125217612208 2.441666603791859e-05 0.0220937986418052 0.0043870035131843 83 P55899,P42892,P04439,P01889,P13591,P05556,P08183,P01130,P11279,Q08431,P10619,P10321,P51790,P02786,P17900,Q8TCT8,P43121,P06756 18 +Endocytic vesicle 0.7112950580558627 4.130440347920764 3.6206903794022693e-05 0.0325871317025482 0.0043870035131843 89 Q06481,O43493,P01130,P20645,Q5KU26,P11717,P02786,Q14108,Q07954,Q93050,P13473,O00461,P11279,Q9Y4G8,P51790,P04439,Q8WTV0,P06756,P01889,P10321 20 +Intrinsic component of plasma membrane 0.7171435490262371 4.117163993558387 3.835631486936997e-05 0.0344879544301546 0.0043870035131843 98 Q6PCB8,Q9UIQ6,O60245,P01130,P30825,Q92859,P20645,P05067,P11717,O00400,Q9Y6N7,P02786,Q9NPF0,P78310,P05556,Q07954,Q14517,P48960,Q13740,Q15043,P19022,P33527,Q92542,O15118,P11279,P10586,Q13641,Q9Y4G8,O60637,P51790,P04439,Q8WTV0,P06756,P11166,P01889,O43657,Q9P273,P27105,Q96QD8,P35613,Q15375,P29317,Q9H2J7,P10321,O14786 45 +Azurophil granule lumen 0.8732641924555367 4.041437014468787 5.312465075446582e-05 0.0474477774457564 0.0054010061600374 41 P04066,P15586,O00584,P61916,P02792,P06280,P10619,Q9BTY2,O00754,P16278,P17900,P53634,Q92820 13 +Secretory granule membrane 0.7162552764549794 3.980065031221987 6.889641843565997e-05 0.0610963315917916 0.0063040222868629 81 Q9NV96,O60245,Q06481,P84095,P11717,P07602,Q15643,P42785,Q93050,P13473,P10253,P48960,Q6YHK3,O15260,Q9NQX7,Q92542,P11279,Q08431,P06756,P01889,P27105,P35613,P10321 23 +Endocytic vesicle membrane 0.8118342483025746 3.88876895423456 0.0001007539760227 0.0880722674036161 0.008160451937615 47 Q14108,P01889,Q06481,O43493,P01130,Q07954,P11279,P13473,P20645,Q5KU26,P11717,P02786,P04439,Q8WTV0,P10321 15 +Coated vesicle 0.6824153233501123 3.874093499917995 0.0001070223204933 0.093288230411934 0.008160451937615 93 Q14108,P42892,Q99523,P01889,Q5VW38,O43493,P01130,P10321,P20645,P05067,P11717,P02786,P04439,P53634,O43731 15 +Early endosome 0.6942001478575361 3.853115387825518 0.0001166243958152 0.101220498298425 0.0082085632439216 111 Q9NV96,Q9UIQ6,Q06481,O95219,P01130,P05067,P11717,P02786,Q9Y2I1,Q9H4M9,Q99523,Q07954,Q9UEU0,Q8IV08,Q9HC07,P49768,Q15043,O15400,Q13510,Q92542,P51790,P04439,P42566,P01889,Q9UMY4,Q5VW38,Q8N3F8,Q9UNF0,Q9NP58,Q96L92,P10321,O14786 32 +Vesicle lumen 0.6931828486067162 3.797326464293747 0.0001462651037091 0.1252720527218439 0.0095594692781361 119 P15586,O00584,O00560,P61916,P67870,P06280,Q9BTY2,P05067,P04066,Q9UEU0,Q08380,O75874,P10619,O00754,P16278,P17900,P53634,Q92820,Q8NBX0,Q92520,Q8NBF2,P02792,P07686,Q9Y376,Q99536,P09429,P04080 27 +Transport vesicle 0.6774330825959413 3.7735940812848945 0.0001609124981338 0.1369190426048003 0.0098156623861667 102 Q9NV96,O43493,P20645,P05067,P11717,P50897,O43760,Q99523,Q9GZM5,Q15643,Q9UEU0,P49768,O00461,O15260,Q92542,P11279,P51790,Q7L0J3,P04439,O43731,P01889,Q9Y678,P35606,P10321 24 +Clathrin coated vesicle 0.774542346930819 3.68472290345514 0.0002289515843865 0.1890222698530069 0.012695730602966 49 Q14108,P42892,Q99523,Q5VW38,O43493,P01130,P11717,P02786 8 +Vacuole 0.7264361990053214 3.677125549247452 0.0002358769620223 0.1941461485101432 0.012695730602966 228 P42892,Q9NV96,Q8NHP8,O14773,Q9UIQ6,P01130,P15586,O00584,O75503,P61916,Q5BJF2,P06280,Q9UMR5,P20645,Q9BTY2,P50897,O95772,Q99538,P07602,P06865,Q14108,Q99523,P04066,P42785,Q07954,Q9UEU0,P54802,Q8IV08,Q9UM22,P13473,Q8NCC3,Q93050,P10619,P10253,O00754,P16278,P17900,P53634,Q92820,Q8TCT8,Q9Y2E5,Q9H2V7,P11117,Q9UHG3,Q15043,Q9NQX7,Q13510,Q92542,O15118,P11279,Q8IW92,P02792,P51790,O00115,P07686,P38571,Q8WTV0,Q9NUM4,P04062,P27105,Q13137,P08195 62 +Endoplasmic reticulum lumen 0.7035072529568186 3.564279465936086 0.0003648570622867 0.2838782821839118 0.018546900666242 69 P19022,O43852,Q06481,O43493,Q13438,Q08431,O00584,Q9H173,P07942,Q14118,P11047,Q9BTY2,P05067,Q32P28,Q14257,Q02818,P53634 17 +External side of plasma membrane 0.886363914355491 3.5286720288336957 0.0004176503916679 0.317661857008371 0.0201131635987469 27 P55899,P42892,P05556,P13591,P01130,P08183,P11279,Q08431,P51790,P02786,P43121,P06756 12 +Vacuolar membrane 0.6361941014099252 3.2359033792437164 0.0012125842143837 0.6705029211133693 0.0532021560048569 133 P42892,Q9NV96,Q9Y3E7,Q9UIQ6,P01130,O75503,P20645,O95772,P07602,Q8IY95,Q14108,Q99523,P42785,Q07954,Q9UEU0,P51798,P60520,Q8IV08,Q93050,P13473,P10619,Q9HC07,P10253,P49768,Q9H2V7,Q8TCT8,Q15043,P11117,O15260,Q9NQX7,O15400,Q92542,O15118,P11279,P51790,Q8WTV0,Q9NUM4,Q8N122,Q9BZH6,P04062,P27105,Q13137,P08195 43 +Pigment granule 0.6765244610379018 3.2288283164248095 0.0012429849093094 0.6795530763106788 0.0532021560048569 62 P05556,O14773,O43852,Q92542,P11279,Q93050,P27105,P35613,P02786,Q92820,P55209,P08195,P11166 13 +External encapsulating structure 0.7419849864570376 3.2206107616327246 0.0012791775214282 0.6900042453089379 0.0532021560048569 40 P19022,P13591,P53634,O94898,P07942,Q08380,Q08431,P04080,Q92896,P11047,Q5KU26,Q32P28,P07602 13 +Coated vesicle membrane 0.6812465019548393 3.1955569687166276 0.0013956122806928 0.7213718425037831 0.0555210972536503 58 Q14108,P01889,Q9Y678,O43493,P01130,Q9UEU0,P20645,P10321,P11717,P02786,P04439,O43731 12 +Exocytic vesicle 0.700889989341468 3.161367494342104 0.0015703024518374 0.7625874780770403 0.0598677809763018 45 Q92542,P11279,P51790,P05067,P50897,Q7L0J3,O43760 7 +Recycling endosome 0.6967515505108977 3.134072581264707 0.0017239820741379 0.7937785948102694 0.0603153565764349 45 P05556,P01889,O15400,O14773,Q9UEU0,O15127,Q8N3F8,P51790,Q9UNF0,P05067,P02786,P04439,P10321,Q9Y2I1,Q9H4M9 15 +Apical part of cell 0.645442230011971 3.1331866192522253 0.001729194606389 0.7947615122302039 0.0603153565764349 69 Q9NV96,P19022,P33527,P30825,P01130,P08183,Q9Y4G8,Q14517,P51790,P05067,Q99538,P08195,Q15043 13 +Early endosome membrane 0.6802768500017938 3.103234435654353 0.0019141794235473 0.8267730392977514 0.0603153565764349 52 Q9NV96,P01889,O15400,Q9UMY4,O95219,Q9UEU0,Q06481,Q8IV08,Q9HC07,P10321,P51790,Q9NP58,Q96L92,P49768,P04439,P42566,Q15043,Q9H4M9 18 +Clathrin coated vesicle membrane 0.828524774370524 3.090160367949338 0.0020004844987742 0.8399512221363987 0.0603153565764349 24 Q14108,O43493,P01130,P11717,P02786 5 +Membrane microdomain 0.6271592284979342 3.0781725454204016 0.0020827428462315 0.8515781936197253 0.0603153565764349 73 P05556,P19022,O14773,P78536,O15118,Q8WTV0,O00560,P13473,P27105,Q14118,P07437,P35613,P05067,P50897,P49768,P78310,P10644,P11166 18 +Ficolin 1 rich granule 0.5847367052752765 3.068225220438596 0.0021533426047302 0.8608820171257415 0.0603153565764349 86 Q13510,P42785,P09429,P11279,P15586,P04080,O75874,Q93050,P13473,P67870,Q9UJU6,Q13442,P10253,Q9Y376,P16278,P08238,P09960 17 +Clathrin coated endocytic vesicle 0.8634679631329378 3.064177963183156 0.0021826902698618 0.8645759572973344 0.0603153565764349 19 Q14108,O43493,P01130,P11717,P02786 5 +Clathrin coated endocytic vesicle membrane 0.9088169922391668 3.0390742986573858 0.0023730632095646 0.8862705957093259 0.0603153565764349 15 Q14108,O43493,P01130,P11717,P02786 5 +Endosome membrane 0.6168243802251112 3.01409567531466 0.0025774650993424 0.9057142411449308 0.0620626464710083 142 P55899,P42892,Q9NV96,Q9Y3E7,Q06481,O95219,P01130,O15127,P11717,P02786,O95772,Q9NPF0,Q9H4M9,Q14108,Q99523,P05556,Q9UEU0,Q8IV08,Q93050,P13473,Q9HC07,P49768,Q8TCT8,O00461,Q15043,O15400,Q92542,O15118,P11279,Q15904,P51790,P04439,P42566,Q9NUM4,P01889,Q9UMY4,Q9ULC3,Q8N3F8,O60664,Q9UNF0,Q9NP58,Q96L92,P10321 43 +Distal axon 0.6346613996193232 2.9740546955824847 0.0029389268373123 0.932327634712976 0.062751213884576 65 O94898,O14656,Q92859,A0MZ66,P05067,Q8TAG9,P78310,Q96A49,Q2M2I8,Q99828,P80723,P49768,P08238,Q13561,P51114,Q05682,Q14247,Q13641,P07900,Q06787,P51790,Q6IBS0,Q99720,O75312,Q9UPT5,P43034 26 +Azurophil granule membrane 0.8123145143605263 2.9663262418683476 0.003013806062768 0.9368218269372914 0.062751213884576 23 Q9NV96,Q9NQX7,P42785,Q92542,P11279,P13473,P27105,P10253,P07602 9 +Tertiary granule 0.691764036519389 2.9495260938499284 0.0031826169616204 0.945890116284528 0.062751213884576 41 O15400,Q13510,P42785,P11279,O75874,P04080,Q93050,P13473,P27105,P10253,Q08722,Q92820,P09960 13 +Clathrin coated pit 0.791509224399732 2.9456002852864676 0.0032232863962569 0.9478729109515008 0.062751213884576 25 P01130,P02786,P05067,Q99523 4 +Secretory granule 0.649087467578642 2.9371301051505982 0.0033126509371803 0.9519785345034576 0.0631474084900006 248 P42892,Q9NV96,O60245,Q06481,P15586,O00584,O00560,P61916,P06280,P84095,Q9BTY2,P05067,P11717,P07602,P78310,P06865,P04066,P42785,Q15643,P22466,Q9UEU0,Q08380,Q93050,P13473,P10619,P10253,P48960,O00754,P16278,P17900,P53634,Q92820,Q6YHK3,O15260,Q9NQX7,Q13510,Q92520,Q92542,P11279,Q08431,P02792,P51790,P07686,P06756,P01889,P09429,P04080,P27105,P35613,Q08722,Q9UQB8,P10321 52 +Golgi associated vesicle 0.7399690610852191 2.915738592097408 0.0035484767371942 0.9613276566126104 0.0662623717251583 32 Q99523,Q9Y678,O43493,O43731,P05067,P11717,Q8TCT8 7 +Secretory vesicle 0.6477315463351105 2.8997846616763554 0.0037341910180854 0.9673914309581244 0.0683356956309642 275 P42892,Q9NV96,O60245,Q06481,P15586,O00584,O00560,P61916,P06280,P84095,Q9BTY2,P05067,P11717,P50897,P07602,P78310,O43760,P06865,P04066,P42785,Q15643,P22466,Q9UEU0,Q08380,Q93050,P13473,P10619,P10253,P48960,O00754,P16278,P17900,P53634,Q92820,Q6YHK3,O15260,Q9NQX7,Q13510,Q92520,Q92542,P11279,Q08431,P02792,P51790,P07686,Q7L0J3,P06756,P01889,P09429,P04080,P27105,P35613,Q08722,Q9UQB8,P10321 55 +Basal part of cell 0.6410515307247311 2.840852030411344 0.0044993183585784 0.9838553368855142 0.0776361323660983 53 P19022,P33527,P42785,Q07954,P30825,P01130,P35613,P02786,P08195,P78310,Q15043,P11166 12 +Site of polarized growth 0.6289173979480371 2.7913160122611766 0.0052494192676371 0.9918998279625928 0.0842669935068062 56 O94898,Q9UJU6,Q92859,A0MZ66,P05067,Q8TAG9,P78310,Q96A49,Q99828,P80723,P49768,P08238,Q13561,P51114,Q14247,P07900,Q06787,Q6IBS0,Q99720,O75312,P43034 21 +Endosome 0.6286574880549723 2.768098168122796 0.0056384469025141 0.9943368709278562 0.0861062913854171 233 P55899,P42892,Q9NV96,O14773,Q9UIQ6,Q06481,O43493,P01130,O95219,O15127,P20645,P05067,P11717,P02786,Q99538,P07602,Q9NPF0,O95772,Q9Y2I1,Q14108,Q99523,P05556,Q07954,Q9UEU0,Q8IV08,Q93050,P13473,Q8TCT8,O00461,Q15043,Q13510,Q92542,O15118,P11279,Q9Y4G8,Q15904,P51790,Q96PU5,P04439,Q9NUM4,P10644,P01889,Q9UMY4,Q5VW38,P09429,Q9ULC3,Q8N3F8,P35613,P10321,O14786 50 +Basolateral plasma membrane 0.6360766816178045 2.7412134716067156 0.0061212723512953 0.9963687451212916 0.087969598266423 47 P19022,P33527,Q07954,P30825,P01130,P35613,P02786,P08195,P78310,Q15043,P11166 11 +Trans golgi network transport vesicle 0.8678690336954171 2.7339709860633685 0.0062575558096236 0.9967969537896164 0.087969598266423 13 P11717,O43493 2 +Phagocytic vesicle 0.6360702713300872 2.7320057431631155 0.0062950043643779 0.9969055182258656 0.087969598266423 46 P01889,Q06481,P11279,Q93050,P13473,P51790,P04439,P10321,P06756 9 +Collagen containing extracellular matrix 0.7031313778875009 2.729915370101815 0.006335058617753 0.9970175715162688 0.087969598266423 33 P19022,P13591,P53634,P07942,Q08380,Q08431,P04080,P11047,Q32P28,P07602 10 +Late endosome 0.5731085778920076 2.7293802991245095 0.0063453480716764 0.9970456963466292 0.087969598266423 77 Q9NV96,Q9Y3E7,P01130,P20645,P11717,O95772,Q99538,P07602,Q8IY95,Q14108,Q9UEU0,Q8IV08,P13473,Q9HC07,Q8TCT8,Q15043,O15400,O15118,P11279,Q9Y4G8,P13693,P51790,Q96PU5,Q9NUM4,P10644,Q8N3F8,Q9NP58 27 +Lumenal side of membrane 0.9168071899224736 2.6851170064705694 0.0072504418793708 0.9987167013949282 0.0961471640525264 10 P10619,P01889,Q8TCT8,P04439 4 +Presynapse 0.5382891743198756 2.594857085782424 0.0094630257793644 0.9998333971125004 0.1160444671081476 98 P19022,P49768,O15400,Q92542,Q9UEU0,P11279,Q13641,P51790,P05067,P50897,Q7L0J3,Q9UQB8,O43760,P11166 14 +Apical plasma membrane 0.6077068142870086 2.588529605336081 0.0096386661204581 0.999858350963734 0.1160444671081476 52 Q9NV96,P30825,Q99828,P78536,P08183,P04920,Q14517,O75787,P49768,P08238,Q15043,P19022,P33527,Q12959,O43865,O75955,Q9Y4G8,P51790,P11166,Q16181,P08195 21 +Neuromuscular junction 0.7363909338412149 2.5757263649595936 0.0100029773257974 0.99989884019673 0.1167974241211384 23 P05556,P11047,Q15375,P05067,P49768,Q7L0J3,O43760,P10644 8 +Platelet alpha granule 0.7616314701054631 2.573311732320076 0.0100730433700875 0.9999051837337016 0.1167974241211384 19 Q6YHK3,O60245,Q06481,Q9UEU0,P05067,Q8NBX0 6 +Vesicle membrane 0.6140565614799488 2.5605154791977824 0.0104517007295625 0.9999331883808312 0.1167974241211384 279 P55899,P42892,Q9NV96,Q9UIQ6,Q06481,O43493,P01130,O60245,O95219,O15127,P84095,P20645,Q5KU26,P11717,P02786,O95772,P07602,Q9NPF0,O43760,Q14108,Q99523,P05556,Q15643,P42785,Q07954,Q9UEU0,Q8IV08,Q93050,P13473,P10253,P48960,Q8TCT8,O00461,Q15043,Q6YHK3,O15260,Q9NQX7,Q92542,O15118,P11279,Q08431,Q15904,P51790,Q7L0J3,P04439,Q8WTV0,O43731,Q9NUM4,P06756,P01889,O43924,Q9Y678,Q9UMY4,Q9ULC3,Q8N3F8,P27105,P35613,P35606,Q96L92,P10321 60 +Phagocytic vesicle membrane 0.6919728826516826 2.539223819185992 0.0111098723238096 0.9999636539062444 0.119594507956304 28 P01889,Q06481,P11279,Q93050,P13473,P04439,P10321 7 +Blood microparticle 0.7595765808880245 2.5085544191180817 0.0121226293739364 0.999985767572634 0.1274966192776079 18 P04062,Q08380,O00560,P27105,P02786,P11166 6 +Cell body 0.5408429270844383 2.491232970378141 0.0127300617491454 0.9999918929920758 0.1304378100681911 115 O94898,Q9UJU6,A0MZ66,P05067,P50897,P78310,Q13283,Q96A49,Q99828,Q8TEY7,Q66K74,P04350,P22466,Q9UEU0,O75787,Q13740,P49768,P08238,P51114,P10586,Q9H814,Q9Y4G8,Q06787,Q7L0J3,P78559,O75312,Q8N122,P43034,Q96QD8,P07437,Q15375,Q14168,Q14203,Q9UQB8,P08195 35 +Golgi membrane 0.5579126042586454 2.4728999653722465 0.0134021651550899 0.9999956524497988 0.1318600120097561 142 P13591,Q7LGA3,O00400,P11717,Q6ZRP7,Q10472,Q14108,Q8IZA0,Q15643,P78536,P60520,Q8IV08,Q8NBN3,Q9HC07,Q7L5N7,O00461,O15260,Q92896,P51790,Q10713,Q15392,P04439,O43731,O60476,P11166,P01889,Q9Y678,O43505,P35613,P35606,P10321 31 +Golgi apparatus subcompartment 0.5233510065032181 2.4555265380176676 0.0140678365297395 0.9999976555734372 0.1354954781548597 98 Q99523,Q10472,Q9NX62,Q9BZH6,P04062,O43493,O15127,Q8NBN3,P20645,Q10713,P05067,P11717,P04439,Q96ED9,O00461,Q4J6C6 16 +Lumenal side of endoplasmic reticulum membrane 0.9071503722711708 2.441267697260543 0.0146358011524876 0.9999986162653284 0.1394974797346478 8 P04439,P01889,Q8TCT8 3 +Ficolin 1 rich granule membrane 0.741057922961952 2.417082734447505 0.0156454605421603 0.9999994584147688 0.1449428947173352 18 P11279,P10253,P13473,P42785 4 +Recycling endosome membrane 0.6921685069621568 2.4119564983289674 0.0158671745759808 0.9999995592911374 0.1449428947173352 25 P01889,Q9UEU0,O15127,Q8N3F8,Q9UNF0,P02786,P04439,P10321,Q9H4M9 9 +Ficolin 1 rich granule lumen 0.5432270466262147 2.301890258022622 0.0213413617428992 0.999999997323428 0.189585883444202 68 P15586,Q9UJU6,Q13200,P67870,Q15008,O75874,Q13442,P16278,P08238,Q13510,Q99436,O43242,P07900,Q9Y376,P09960,P51665,P28482,P09429,P04080,P00491,P06737 21 +Tertiary granule lumen 0.7431439263575479 2.287986804043557 0.0221382896012714 0.9999999987298396 0.1929193808110793 15 Q13510,P04080,O75874,Q92820,P09960 5 +Golgi apparatus 0.5838441716093442 2.273746895923663 0.0229812087894489 0.9999999994230092 0.1983755287013756 338 Q9NV96,P13591,O14773,O43493,P01130,Q7LGA3,O75503,O15127,Q92859,P06280,P20645,Q14118,P05067,P11717,P50897,O00400,Q6ZRP7,Q10472,Q8IY95,Q4J6C6,Q14108,Q99523,Q8IZA0,P80303,Q15643,Q8TEY7,Q07954,P22466,Q9UEU0,Q9GZM5,P78536,Q8IV08,Q93050,P60520,Q8NBN3,Q9HC07,A9UHW6,P16278,Q7L5N7,Q02818,P53634,Q96ED9,O00461,Q9NX62,O15260,Q9NQX7,Q92520,Q92542,O15118,Q92896,P51790,Q10713,Q15392,Q96PU5,P04439,O43731,O60476,P11166,P01889,Q9Y678,O43852,P04062,Q5VW38,Q9BZH6,O43505,Q8N3F8,O95456,P35613,P35606,Q9UQB8,P10321 71 +Endolysosome 0.8150998314673656 2.270111226831422 0.0232008353280046 0.999999999530289 0.1983996665899463 10 P01130 1 +Copii coated er to golgi transport vesicle 0.6223478489555718 2.2608328012812096 0.023769612587468 0.9999999997243396 0.2013814399771595 34 P01889,P05067,P04439,P53634,P10321 5 +Endosome lumen 0.9894736468850068 2.2467530958528714 0.0246558108733139 0.9999999998799176 0.2069730912759838 4 P05067,Q9UIQ6 2 +Anchored component of membrane 0.7826611223449587 2.2303054020784123 0.0257271747953513 0.9999999999560722 0.2140033176158772 11 Q6YHK3 1 +Nuclear envelope lumen 0.9265932120506236 2.2264790997191923 0.0259821074036357 0.9999999999654264 0.2141768313002403 5 P05067 1 +Lamellipodium 0.5316895782276512 2.174546206572796 0.029664139214282 0.9999999999989192 0.235034506363732 66 Q9UHY1,Q9UJU6,Q14118,P47756,A0MZ66,P05067,Q99828,P05556,Q14517,P19022,Q14247,O75955,Q6IBS0,P06756,Q13418,Q14444,O60749,P29317,Q9UQB8 19 +Ruffle membrane 0.6262956181856335 2.1710561735012446 0.02992692639909 0.9999999999991566 0.235034506363732 29 P05556,P23396,P78536,Q06481,P51790,P29317,P06756 7 +Golgi lumen 0.8798632458044132 2.1693833415651724 0.0300535926170018 0.9999999999992516 0.235034506363732 6 P05067,O00461,Q9NX62 3 +Autophagosome 0.6114243994081706 2.1657484159655644 0.0303304171044309 0.9999999999994236 0.2351892512758842 33 Q9Y3E7,P11279,Q9ULC3,P13473,P02792,Q13137 6 +Platelet alpha granule lumen 0.7642282986424378 2.149827635760942 0.0315688513343419 0.999999999999821 0.2407124914243573 11 P05067,Q8NBX0,Q9UEU0 3 +Sarcolemma 0.6233243786454364 2.134530359877119 0.0327993911850421 0.999999999999944 0.2459954338878162 28 P05556,P19022,Q92542,P11279,Q14118,Q96QD8,P35613,P11166 8 +Axon 0.5167127824104405 2.0886940910506775 0.0367352691108628 0.9999999999999988 0.2710707357777382 140 Q6PCB8,O94898,Q92859,Q14118,A0MZ66,P05067,P50897,Q9Y6N7,Q8TAG9,P78310,Q96A49,Q99828,P04350,P04792,O75787,P80723,Q13740,P49768,Q13561,P08238,P51114,Q14247,Q12959,Q13641,P07900,Q06787,P51790,Q6IBS0,Q99720,P07197,P78559,O75312,Q9UPT5,Q9P273,P43034,Q96QD8,P46060,P35613,Q14203,Q14168,O14786 41 +Platelet alpha granule membrane 0.8874528990366892 2.079962514239614 0.0375289712785522 0.9999999999999992 0.2747120697590025 5 Q6YHK3,Q06481 2 +Proteasome core complex 0.697216270805416 2.06666936439122 0.038765319801445 0.9999999999999998 0.2811491029318937 15 P28070,P28074,Q99436,P25788,P28072,Q92530,P60900,P49721 8 +Platelet dense granule 0.938186473260046 2.060281981453981 0.0393715914598149 1.0 0.2811491029318937 4 Q08380,P13473 2 +Intrinsic component of presynaptic membrane 0.8505993476540514 2.0575237286880443 0.0396358748283738 1.0 0.2811491029318937 6 P19022,Q92542 2 +Trans golgi network 0.5066701317661408 2.057203061808657 0.0396666971580417 1.0 0.2811491029318937 72 Q9NX62,Q9BZH6,P04062,O43493,O15127,P20645,P05067,P11717,Q96ED9,Q4J6C6 10 +Dendritic shaft 0.7856177705372244 2.0543205062456247 0.0399446812908701 1.0 0.2811491029318937 9 P49768,P78559,Q9UQB8,P05067 4 +Desmosome 0.8028188050143393 2.028938168156111 0.0424645885483898 1.0 0.2899634218043039 8 Q14574,Q02487 2 +Multivesicular body 0.6876269951408703 2.0197249291366486 0.0434119277809246 1.0 0.2942363994040446 15 Q9UQN3,Q9Y3E7,Q9H444,P11279,P13693,Q9NP58,Q96PU5,P10644 8 +Glial cell projection 0.864551643138363 1.9932308630386313 0.0462361730189697 1.0 0.3065659297996908 5 P05556,P05067,Q06787 3 +Perinuclear region of cytoplasm 0.5420470801687233 1.987340458590278 0.0468846810345273 1.0 0.30705428794945 208 O60271,P42892,Q9UIQ6,Q07960,P19525,Q99598,O75503,P26583,Q12834,P20645,A0MZ66,P05067,Q8NC51,P11717,Q8NCE2,Q8TAG9,P02786,Q99538,Q10472,Q8IY95,Q92905,Q96A49,Q99828,P05556,Q99523,Q66K74,Q9H4M9,Q8TEY7,Q9H223,Q9Y3A3,Q9UEU0,O00299,P39687,Q93050,Q14517,Q92530,P16278,P49768,P08238,P55327,P51114,Q9NQX7,O15400,Q12959,O15118,P11279,Q9Y4G8,P07900,Q06787,P06730,Q13177,O95831,O75312,P07942,P43034,P27105,Q15056,Q01105,Q13137 59 +Golgi cisterna membrane 0.673038329074531 1.986041099134672 0.047028760562515 1.0 0.30705428794945 16 O00461,Q99523,Q10472,Q8NBN3 4 +Transport vesicle membrane 0.5344714364099674 1.9817328971850845 0.0475091432356773 1.0 0.30705428794945 44 Q9NV96,P01889,Q7L0J3,P04439,P10321,O43760 6 +Protein lipid complex 0.8550928855253851 1.9572001875293248 0.0503239367879746 1.0 0.3153863161712109 5 P01130 1 +Cornified envelope 0.7810465690049491 1.940426033668111 0.052327935257507 1.0 0.3235139240582359 8 Q14126,Q14574,Q02487 3 +Leading edge membrane 0.5335608534004183 1.9362213933119667 0.0528405913883884 1.0 0.3244908800025198 43 P05556,P23396,P78536,Q06481,P51790,Q9UNF0,P29317,P06756 8 +Neurofilament 0.9011604876509248 1.9236808559674352 0.0543945990999867 1.0 0.3274683459072836 4 O14786 1 +Golgi cisterna 0.621622092647257 1.9182759270044856 0.0550760331800386 1.0 0.3274683459072836 22 P04439,Q99523,Q8NBN3,Q10472,O00461 5 +Specific granule 0.5578103084543271 1.9151546822577343 0.0554727799077912 1.0 0.3274683459072836 37 Q9NV96,P27105,P51790,Q92820,P06756 5 +Filopodium 0.5428837748233738 1.8999848982487568 0.0574351014878611 1.0 0.3347332347859422 40 P05556,Q14517,Q14118,Q9UQB8,P05067,P78310,P06756 7 +Acrosomal membrane 0.8900145462155485 1.8822577965848084 0.0598010216972033 1.0 0.3422239400763233 4 Q08431,Q15643 2 +Proteasome core complex beta subunit complex 0.7847520308122923 1.8648156771605808 0.0622072450648094 1.0 0.3454542925337661 7 P49721,P28070,P28074,P28072 4 +Endolysosome membrane 0.7402104086402783 1.8634605154944528 0.0623975027617005 1.0 0.3454542925337661 9 P01130,Q9NP58 2 +Postsynaptic specialization membrane 0.6875239349585073 1.8609111787610335 0.0627567208709871 1.0 0.3454542925337661 12 P19022,Q12959,Q15375,Q99720,Q14168 5 +Tertiary granule membrane 0.6968950851222419 1.849444855012819 0.0643936035960202 1.0 0.3454542925337661 11 P10253,P27105 2 +Neuron projection terminus 0.6383826856495247 1.8487921366977664 0.0644878332330392 1.0 0.3454542925337661 17 P51790,Q9UQB8,Q13641 3 +Intercalated disc 0.6304539687940447 1.8485385850794045 0.064524467874127 1.0 0.3454542925337661 18 P05556,P19022,Q02487,Q14126 4 +Immunological synapse 0.6562538782609967 1.8303902992139067 0.0671915972515051 1.0 0.3486400631567259 14 P35579,O15400,Q12959,P15311,P17931,P52565,Q8WUM4,Q96L92,Q13740,P10644 10 +Specific granule membrane 0.6335588180777229 1.8236572669501696 0.0682039030656327 1.0 0.3486400631567259 17 Q9NV96,P06756,P27105,Q08722 4 +Intrinsic component of postsynaptic specialization membrane 0.8668919139430838 1.7959128356919534 0.0725083807295119 1.0 0.3574526733453997 4 Q15375 1 +Presynaptic active zone 0.63405057105111 1.78802753255146 0.0737715659330049 1.0 0.3577730464224659 16 Q7L0J3,P05067 2 +Cell cell junction 0.4710228296325897 1.7747088543219136 0.0759459725726303 1.0 0.3638249471411349 120 Q14126,O00560,Q14118,P05067,P78310,P05556,P78536,Q14517,Q14574,P19022,Q02487,Q9Y4G8,Q86VI3,Q7L0J3,P11166,Q9Y624,Q92692,P29317,Q9UQB8 19 +Smooth endoplasmic reticulum 0.6676951169773077 1.7683603319090266 0.0770006837099397 1.0 0.3659741504731811 12 P05067 1 +Sorting endosome 0.8592339244567095 1.7672011476064229 0.0771945475861464 1.0 0.3659741504731811 4 P01130 1 +Trans golgi network membrane 0.5592025241068237 1.7532132433247716 0.0795654106353747 1.0 0.3739648166607824 29 O15127,P20645,Q9HC07,P05067,P11717,P09496,Q9NX62 7 +Lamellipodium membrane 0.7700672934095001 1.7430888988131996 0.0813180874298125 1.0 0.3776956852704489 6 P06756 1 +Autophagosome membrane 0.6222803673902797 1.7274308583521794 0.0840903126359706 1.0 0.3847131803095658 16 P11279,Q9Y3E7,Q13137,P13473 4 +Main axon 0.6584188320123842 1.7247736710526649 0.0845682683844077 1.0 0.3849749530931996 12 P78559,Q14168,P05067,Q14118 4 +Secondary lysosome 0.9774145616641904 1.7194184222198396 0.0855382101637656 1.0 0.3855540014770716 3 P11279,P13473 2 +Autolysosome 0.9774145616641904 1.7194184222198396 0.0855382101637656 1.0 0.3855540014770716 3 P11279,P13473 2 +Postsynaptic density membrane 0.725508354306261 1.711047691479451 0.0870723092326115 1.0 0.3876017412783239 8 Q15375,Q99720,Q14168 3 +Axonal growth cone 0.7453430152283692 1.706352894362385 0.0879423953941263 1.0 0.3887308781914278 7 P08238,A0MZ66,P07900,Q92859 4 +Tim23 mitochondrial import inner membrane translocase complex 0.7601292754362625 1.7036725610063803 0.0884422770937995 1.0 0.3890609785616664 6 Q99595 1 +Late endosome membrane 0.5064310447366593 1.6973263856965248 0.0896349714472894 1.0 0.3924210472453104 42 Q14108,Q9NV96,Q9UEU0,O15118,P11279,Q8IV08,P13473,Q8N3F8,P51790,O95772,Q8TCT8,Q9NUM4,Q15043 13 +Organelle envelope lumen 0.5143163297040834 1.6927369006467934 0.0905055580694518 1.0 0.393271592754485 40 O00584,P05067 2 +Plasma membrane raft 0.5859851625883103 1.6917751201713729 0.0906888590942036 1.0 0.393271592754485 21 P19022,Q14118,Q8WTV0,P10644,P11166 5 +Platelet dense granule lumen 0.9420677361853852 1.6732302846165523 0.0942819706412128 1.0 0.4035664090848744 2 Q08380 1 +Mhc class i protein complex 0.963744427934621 1.67035123065311 0.0948498926681926 1.0 0.4035664090848744 3 P04439,P01889 2 +Mhc protein complex 0.963744427934621 1.67035123065311 0.0948498926681926 1.0 0.4035664090848744 3 P04439,P01889 2 +Ruffle 0.4816180070957016 1.6699531841866695 0.0949286265207283 1.0 0.4035664090848744 59 P05556,P23396,P78536,Q06481,P51790,Q10713,Q9UNF0,P29317,Q9UQB8,P06756 10 +Laminin complex 0.9385026737967924 1.6590910321902188 0.0970974500768102 1.0 0.4035664090848744 2 P07942 1 +Intrinsic component of vacuolar membrane 0.9582806555497014 1.650715969574427 0.0987965853934556 1.0 0.4035664090848744 3 P13473 1 +Cell leading edge 0.4586329702632493 1.6335474330048387 0.102353913250514 1.0 0.4083123251420695 122 Q9UHY1,Q06481,Q13596,P15311,Q9UJU6,Q9H6U6,Q14118,P47756,A0MZ66,P23258,P05067,Q8NCE2,Q2M2I8,Q99828,P05556,P78536,Q9H2G2,O75787,Q14517,P19022,Q14247,O75955,P51790,Q10713,Q6IBS0,P06756,Q13418,Q14444,O60749,P43034,Q9UNF0,Q14168,P29317,Q9UQB8,P23396 35 +Cis golgi network 0.6089944015122091 1.6255464913587514 0.104046166039283 1.0 0.412130917428329 15 O43731,O00461 2 +Golgi stack 0.5306259930691991 1.6171255892226868 0.1058511742604708 1.0 0.4174733812428053 32 P04439,Q14746,Q99523,Q8NBN3,Q10713,Q7L5N7,Q10472,O00461 8 +Ciliary transition zone 0.7010662470529926 1.608606628119897 0.1077023840106876 1.0 0.4229514221878935 8 Q15555,P36405,Q15154,P41208,A6NIH7,Q9Y366 6 +Intrinsic component of golgi membrane 0.6776486033099725 1.5945022065659338 0.1108235969126811 1.0 0.4315046432983118 9 O43505 1 +Synaptic vesicle membrane 0.6072074105888523 1.5863560901914182 0.1126585551704986 1.0 0.4349475864177478 14 O15126,Q7L0J3,Q86Y82,O43760,P09496 5 +Chloride channel complex 0.7541919294419568 1.5661912247342549 0.1173038564664952 1.0 0.449028664193827 5 Q9C0H2 1 +Golgi associated vesicle membrane 0.5676608093184303 1.5478400706280555 0.1216608063102036 1.0 0.4515202298750318 19 P35606,Q9Y678,Q8TCT8,O43731 4 +Cell cell contact zone 0.5359942262591075 1.526000364594523 0.1270097736951634 1.0 0.4611664402026766 26 Q14126,P05556,P19022,Q02487,P11166 5 +Endoplasmic reticulum golgi intermediate compartment membrane 0.5233712178099859 1.5221539270628903 0.1279705163383506 1.0 0.4628182705517425 29 Q15643,Q15904,Q9Y6N7,Q10472,P53634 5 +Ubiquitin conjugating enzyme complex 0.7386317915876954 1.5050268318871962 0.1323171784931456 1.0 0.4663000397503306 5 P49459,Q5VTR2,P61088 3 +Presynaptic membrane 0.5598862323050053 1.504307083301595 0.132502316089438 1.0 0.4663000397503306 19 P49768,Q06787,P19022,Q92542 4 +Integrin complex 0.7891457558050268 1.5023010558368015 0.1330193761068299 1.0 0.4663000397503306 4 P06756 1 +Protein complex involved in cell adhesion 0.7891457558050268 1.5023010558368015 0.1330193761068299 1.0 0.4663000397503306 4 P06756 1 +Clathrin coat 0.5791274487513175 1.5022765782553722 0.1330256949140378 1.0 0.4663000397503306 16 P42566,P11717,P09496 3 +Plasma membrane protein complex 0.443956320233086 1.4906170274260804 0.1360620712461202 1.0 0.4680330646248121 72 O00560,Q92859,Q14118,P02786,P62942,P05556,Q07954,P49768,P19022,Q92542,P04439,P42566,P06756,P01889,P09429,Q9NP58,P08195,P10321,P09496 19 +Actin based cell projection 0.4608462892958174 1.4624592877394589 0.1436153929581065 1.0 0.4778475802060636 55 P05556,Q06787,Q14118,Q14517,Q9UQB8,P05067,Q9BXI6,P78310,P06756 9 +Receptor complex 0.5151682494325219 1.4562258911459394 0.1453301843972942 1.0 0.4813179457491142 28 Q07954,P01130,O00170,Q15375,P05067,P29317,P02786,O14786,P06756 9 +Postsynaptic cytosol 0.6785977936800672 1.433551660683803 0.1517002464895851 1.0 0.4931799263839257 7 Q9UQB8,Q13526 2 +Endoplasmic reticulum 0.4278381879135451 1.4105061905259797 0.1583902698156583 1.0 0.4993352032449152 531 Q6UXD5,Q06481,O43493,O00584,O75503,P61916,Q9BTY2,P05067,Q9NPF0,Q14108,Q99523,Q8IV08,P10619,P53634,Q8TCT8,Q13510,Q92542,O15118,Q08431,Q13641,Q15904,Q15392,Q7L0J3,P04439,Q99720,O43731,Q7Z2K6,P01889,O43852,P04062,P07942,P27105,O95456,Q16850,Q14257,O75844,Q01105,P10321,Q9NV96,Q9BQE5,Q5BJF2,Q9UBM7,P84095,O95302,O00400,O95772,Q10472,P48723,P80303,P07099,Q9UEU0,Q13438,Q9H173,P39687,Q14739,Q96LJ7,Q92530,Q02818,O15260,P19022,P11047,Q32P28,O60476,Q9Y678,P35613,P35606,Q92734,Q9UQB8,P23396,Q9UMX5,O00560,Q14118,Q68D91,P62942,Q8IY95,P78536,O14967 77 +Endoplasmic reticulum golgi intermediate compartment 0.4560396607158413 1.4094047094602584 0.1587155322960585 1.0 0.4993352032449152 53 O15260,P80303,Q02818,Q15643,Q9Y678,Q15904,Q9Y6N7,Q10472,P53634 9 +Photoreceptor connecting cilium 0.6844140392623472 1.4000007474160474 0.1615130946502381 1.0 0.5005953729893656 6 Q15019,Q15555,P36405,P41208,Q9Y366 5 +Aryl hydrocarbon receptor complex 0.8692810457516371 1.384475158141624 0.1662130095224077 1.0 0.5044027044654561 2 O00170 1 +Pericentriolar material 0.7559115024790927 1.3758640824426165 0.1688637170589408 1.0 0.507929025291042 4 Q15154,Q96PY6 2 +Somatodendritic compartment 0.4591090649079334 1.3744253358037786 0.169309675097014 1.0 0.507929025291042 160 O94898,P01130,Q9UJU6,P05067,P50897,Q13283,P05556,P22466,Q9UEU0,Q13740,P49768,P10586,Q9H814,Q13641,Q9Y4G8,Q06787,Q7L0J3,P78559,O75312,Q8N122,Q14444,P43034,Q96QD8,Q15375,Q14168,Q14203,Q9UQB8,P08195 28 +Ciliary rootlet 0.877200700283784 1.3586348571719822 0.1742623239069884 1.0 0.5127114441723581 3 P05067 1 +Chromatoid body 0.8618538324420679 1.3550973662140129 0.1753865377332766 1.0 0.5127114441723581 2 Q08J23 1 +Cell trailing edge 0.6981861433244085 1.3454714186717065 0.1784730451840475 1.0 0.5143001214261405 5 Q14254,P35579,O75955,P15311 4 +Basement membrane 0.6347813620420241 1.3273032882675728 0.1844083765525748 1.0 0.5207829152642159 8 P07942,P11047 2 +Dynein complex 0.5646517225394166 1.3207515497083728 0.1865842194628406 1.0 0.5236949718052123 13 O95219,Q8IVD9,Q96FJ2,O43237,Q9UJW0,Q13561,Q14203,Q13409 8 +Proton transporting v type atpase v0 domain 0.7378841244770935 1.3072566847798828 0.191125549768897 1.0 0.5299390243592146 4 Q93050,O75787 2 +Vacuolar proton transporting v type atpase v0 domain 0.7378841244770935 1.3072566847798828 0.191125549768897 1.0 0.5299390243592146 4 Q93050,O75787 2 +Cop9 signalosome 0.578169522852231 1.2985064878656054 0.1941133483721859 1.0 0.5349810655438257 11 Q7L5N1,P62993,P61201,Q9H9Q2,Q92905 5 +Er to golgi transport vesicle membrane 0.5093945257106084 1.2867234480079806 0.1981906972725267 1.0 0.5378545741366793 23 P04439,P10321,P01889 3 +Multivesicular body membrane 0.6243933973025506 1.2829113862677066 0.1995231232523278 1.0 0.5378545741366793 8 Q9H444,Q9Y3E7,Q9UQN3,Q9NP58,O14964 5 +Sperm connecting piece 0.8434343434343465 1.2824285518082288 0.1996923537013586 1.0 0.5378545741366793 2 P10644 1 +Astrocyte projection 0.8534745061515787 1.2733556881038126 0.2028918539692221 1.0 0.5378545741366793 3 P05067 1 +Plasma membrane region 0.4708039485933452 1.2711978904833705 0.2036582568714198 1.0 0.5378545741366793 201 Q9NV96,P09496,P23396,Q96J42,Q06481,P01130,P30825,Q14118,P05067,P02786,P78310,Q9H4M9,P05556,Q99523,P78536,Q07954,P08183,Q14517,P49768,Q15043,P19022,P33527,Q92542,Q9Y4G8,Q06787,P51790,Q99720,Q8WTV0,P42566,P11233,P10644,P06756,P11166,P35613,Q9UNF0,Q15375,Q14168,P29317,Q9UQB8,P08195,O14786 41 +Eukaryotic translation initiation factor 4f complex 0.6211847451207368 1.269191552879024 0.2043727530767318 1.0 0.5378545741366793 8 Q15056,P23588 2 +Proton transporting v type atpase complex 0.5626337253077929 1.265766317631067 0.2055967573472537 1.0 0.5378545741366793 12 Q15904 1 +F actin capping protein complex 0.6511440789746149 1.2653935503325733 0.2057302860860455 1.0 0.5378545741366793 6 P47756,P52907,P58546 3 +Gamma secretase complex 0.8512496777936067 1.2653755868987622 0.2057367223473636 1.0 0.5378545741366793 3 Q92542 1 +Proteasome complex 0.44062471361838 1.262025743370519 0.2069395231960067 1.0 0.5379251810350743 49 P28074,Q13200,O75832,Q15008,P04792,Q92530,P60900,P49721,Q99436,P54578,P28070,O43242,P25786,Q05086,P28072,P55036,P51665,P25788,Q9BRP4 19 +Cell projection membrane 0.4250212985552858 1.253253514747254 0.2101134599229301 1.0 0.5415600445900877 67 P05556,Q15691,Q96J42,P78536,Q06481,P23396,O75787,P51790,Q9UNF0,P06756,P29317,P08238,Q14168,Q9H4M9,Q99828 15 +Septin cytoskeleton 0.670234909307159 1.2350758319515065 0.2168022830643554 1.0 0.5538455196387695 5 Q15019,Q16181,Q9NVA2,Q9UHD8 4 +Dendrite terminus 0.7148917198387696 1.2198961415724376 0.2225042486987287 1.0 0.5538455196387695 4 P08238,P07900 2 +Caveola 0.5340919991089622 1.2138051360469864 0.2248221445903717 1.0 0.5538455196387695 14 Q8WTV0,P11166 2 +Schaffer collateral ca1 synapse 0.519393226989449 1.2116625455858014 0.2256415819229129 1.0 0.5538455196387695 17 P05556,P47756,Q15375,P11274,Q9UQB8 5 +Non motile cilium 0.5192311630839053 1.2107759059532943 0.2259813017633445 1.0 0.5538455196387695 17 Q01968,Q15555,P46821,Q9UHD8,Q96FJ2,P36405,P35613,P23258,Q15154,P41208,Q16181,Q9Y366 12 +Hippocampal mossy fiber to ca3 synapse 0.7076037870140818 1.1922685228503005 0.2331559727290062 1.0 0.5611150195300495 4 P47756,Q15375 2 +Neuron spine 0.4470779270909383 1.1880669860664808 0.2348070197933551 1.0 0.5611150195300495 40 P05556,Q14247,Q9NVA2,P63000,Q06787,O75787,Q9UQB8,P05067,P46934,P11274,Q14168,P51114 12 +Aggresome 0.5834755238134133 1.180228136460293 0.2379094912669055 1.0 0.566592984018339 9 P49768,P42566 2 +Nucleotide activated protein kinase complex 0.7040968862306862 1.178989109524777 0.238402512401159 1.0 0.566592984018339 4 P10644 1 +Origin recognition complex 0.6194126913057388 1.137039738347892 0.2555216737808108 1.0 0.5874430439935726 6 Q9Y619,Q13416 2 +Cell substrate junction 0.4548697678271122 1.1289185355253322 0.258932200827545 1.0 0.5933221435592898 195 O00560,P84095,Q14118,P67936,P11717,Q13283,Q9UBG0,Q14108,P05556,Q8TEY7,P78536,Q07954,Q14517,P48960,Q13740,Q13308,P19022,Q92542,Q10713,P11233,P43121,P06756,P61513,Q92692,P35613,Q9UNF0,P29317,O14786,P23396 29 +Cilium 0.3844140316650706 1.1081342129955916 0.2678038572192704 1.0 0.6065359637515655 92 Q15691,Q96J42,Q13526,P05067,Q9H4M9,P04350,Q04721,P49768,P28070,Q2M1P5,Q10713,P41208,P10644,Q9P2S5,O43924,Q9BZH6,P43034,P35613,Q15154,A6NIH7,Q14203 21 +Cytoplasmic dynein complex 0.5304643710835039 1.0728960994719223 0.2833177363283008 1.0 0.6321380077626731 11 O95219,Q8IVD9,Q96FJ2,O43237,Q9UJW0,Q13409 6 +Integral component of synaptic vesicle membrane 0.6287134298213256 1.0718073287171423 0.2838065806832781 1.0 0.6321380077626731 5 Q7L0J3,Q86Y82 2 +Ciliary basal body 0.4765061617823271 1.0698865285263517 0.2846703875775951 1.0 0.6322170015376202 22 Q9P2S5,Q9UPT5,Q15691,Q9BZH6,P28070,P15311,Q13526,Q2M1P5,P23258,Q15154,P41208 11 +Snare complex 0.4944236390094883 1.0504143654798257 0.2935276437481762 1.0 0.6378947253670649 16 O15400,O15498,Q9UNK0,O95219,Q9UEU0,Q86Y82,P54920,Q12846,P56962 9 +Lipid droplet 0.4492634411695121 1.0494281022468963 0.2939811298589436 1.0 0.6378947253670649 31 Q8N0X7,O60664,Q7L5N7,O43760,Q99720,Q01105,Q8NBX0,Q9H4M9 8 +Prefoldin complex 0.6691612842331882 1.0474423795581058 0.2948955943500202 1.0 0.6378947253670649 4 Q99471 1 +Cytosolic region 0.568667699902228 1.044782264257046 0.2961236137753444 1.0 0.6390403457651891 8 Q9UQB8,Q13526 2 +Perikaryon 0.4597681226025741 1.04259191640674 0.2971373347160739 1.0 0.6397192029769592 26 O75312,Q9UJU6,Q06787,A0MZ66,Q14168,P05067,Q13283,Q96A49 8 +Apicolateral plasma membrane 0.5947252253009492 1.0376311650741048 0.2994418029075407 1.0 0.6431672527239432 6 P78310 1 +Escrt complex 0.5208927090483129 1.0276910077076618 0.3040951990822456 1.0 0.6436374496060556 11 Q9UQN3,Q9Y3E7,Q9H444,Q99816,Q8WUX9,O14964,Q9BRG1 7 +Myelin sheath abaxonal region 0.6638195768225841 1.0274842705318137 0.3041924883589044 1.0 0.6436374496060556 4 P05556 1 +Filopodium tip 0.578964050581889 1.0221593598232577 0.3067054821137271 1.0 0.6451391175495641 7 Q7L576,Q99828,Q06787,Q9Y4I1 4 +9plus0 non motile cilium 0.5089439870254502 1.004868336009138 0.3149602531320765 1.0 0.6549741627632956 12 Q01968,Q15555,P46821,Q96FJ2,P36405,P35613,P41208,Q9Y366 8 +Retromer complex 0.528191657289452 0.9964806147005332 0.319016681345301 1.0 0.6589170732075631 10 Q9UMY4,Q13596,O60749,O60493,Q9UBQ0 5 +Ciliary membrane 0.605568620508582 0.9817055774751032 0.3262449168638026 1.0 0.66755758814406 5 Q9H4M9 1 +Myofilament 0.7699851411589905 0.9778274636471752 0.3281596654232475 1.0 0.66755758814406 3 P06753,P67936 2 +Striated muscle thin filament 0.7699851411589905 0.9778274636471752 0.3281596654232475 1.0 0.66755758814406 3 P06753,P67936 2 +Mrna cleavage factor complex 0.4822984834390628 0.9650936344837308 0.3344979149707701 1.0 0.66755758814406 15 Q5KU26 1 +Copi vesicle coat 0.5331135932616278 0.9579579010540772 0.3380839875875892 1.0 0.66755758814406 9 P35606,Q9Y678 2 +Amphisome membrane 0.5709364753108037 0.9426266746617388 0.3458718908874367 1.0 0.66755758814406 6 Q9H444,Q9Y3E7,Q9UQN3 3 +Amphisome 0.5709364753108037 0.9426266746617388 0.3458718908874367 1.0 0.66755758814406 6 Q9H444,Q9Y3E7,Q9UQN3 3 +Cyclin dependent protein kinase holoenzyme complex 0.5437525703926336 0.939103301963021 0.3476777091295397 1.0 0.66755758814406 8 Q9P287,P06493 2 +Eukaryotic translation initiation factor 2b complex 0.5698883066773485 0.9384651252997992 0.3480054311964116 1.0 0.66755758814406 6 Q13144,P05198,Q9NR50 3 +Escrt iii complex 0.5936865854419405 0.9358518137048896 0.3493494897954425 1.0 0.6681370804294016 5 Q9H444,Q9Y3E7,Q9UQN3 3 +Copi coated vesicle membrane 0.4831234065847758 0.9137518443103488 0.3608472553148085 1.0 0.6803511497039485 13 Q9Y678,O43731 2 +N terminal protein acetyltransferase complex 0.6328007203928467 0.9127636875283238 0.3613668401706218 1.0 0.6803511497039485 4 Q9GZZ1 1 +Scf ubiquitin ligase complex 0.5513478958196943 0.9094358738287144 0.3631200927953366 1.0 0.6822482236298419 7 Q96K76,Q13309,Q13617 3 +Dendritic tree 0.3890469007855179 0.907819440823604 0.3639736253383769 1.0 0.6824505475094568 121 Q9UJU6,P05067,P50897,Q96A49,P05556,Q66K74,O75787,Q13740,P49768,P08238,P51114,Q14247,Q13641,P07900,Q06787,Q8N2K0,Q7L0J3,P78559,Q8N122,Q14444,Q96QD8,P46060,Q15375,P52294,Q14168,Q9UQB8 26 +Adherens junction 0.3944284039562754 0.8753847352641112 0.3813646026390973 1.0 0.6950636744027452 49 P19022,Q02487,O00560,Q92692,Q9UQB8,P78310 6 +Photoreceptor inner segment 0.5424434159184761 0.8734306231463786 0.3824284055564613 1.0 0.6950636744027452 7 P11166 1 +Dendrite membrane 0.6219592115045462 0.8732499811092269 0.3825268374017931 1.0 0.6950636744027452 4 Q14168 1 +Copi coated vesicle 0.466096321849806 0.8645101679997201 0.3873076970906277 1.0 0.6988692038450898 14 Q9Y678,O43731 2 +Dendritic growth cone 0.7368985728690512 0.8644607402378982 0.3873348383035218 1.0 0.6988692038450898 3 P08238 1 +Dynactin complex 0.5746769352811667 0.8632390061702684 0.388006071642957 1.0 0.6988692038450898 5 Q13561,Q9UJW0 2 +Basal dendrite 0.7329174093880022 0.8592277645903076 0.3902148681858659 1.0 0.7014668062673228 2 P46821 1 +Cytoplasmic stress granule 0.3928035796841033 0.8573318043466194 0.3912615363571576 1.0 0.7016184356077475 45 Q8N122,Q9Y520,Q7Z417,Q14444,Q9UN86,Q14974,Q04637,Q06787,Q14157,P67809,P06730,Q6PKG0,Q99700,Q9BYJ9,Q13283,Q7Z739,O75534,P05198 18 +Hulc complex 0.7344797631371567 0.8562982854700741 0.3918328093940535 1.0 0.7016184356077475 3 P49459 1 +Anchoring junction 0.4552703329903956 0.8401089115930329 0.4008473239321697 1.0 0.7087495085143479 271 Q14126,P23396,O00560,P84095,Q14118,P05067,P11717,P78310,Q9UBG0,Q14108,P05556,Q8TEY7,Q07954,Q14517,Q14574,P48960,Q13740,P19022,Q02487,Q92542,Q9Y4G8,Q86VI3,Q10713,Q7L0J3,P43121,P06756,P11166,Q9Y624,Q92692,P35613,P29317,Q9UQB8,O14786 33 +Proteasome core complex alpha subunit complex 0.5175684615568281 0.7740840800054961 0.4388810712751327 1.0 0.7562639928752287 7 P25788,P60900 2 +Alpha dna polymerase primase complex 0.5477605325519043 0.7624625702293003 0.4457839743768872 1.0 0.7652764288083523 5 P49642,Q14181 2 +Eukaryotic translation initiation factor 2 complex 0.7043090638930173 0.7562417156115656 0.4495042859531901 1.0 0.7702180180658595 3 P20042,P05198 2 +Semaphorin receptor complex 0.7022497495784948 0.7495433491839877 0.4535297811549375 1.0 0.7756630836575099 3 O14786 1 +Endoribonuclease complex 0.4369547178181751 0.7440596330372478 0.4568403990914185 1.0 0.7758080928537202 16 Q5KU26 1 +Postsynaptic recycling endosome 0.6978609625668507 0.7336727322323635 0.4631482211665798 1.0 0.777579123609946 2 Q86Y82 1 +Centriolar satellite 0.4100409582916998 0.7237728368703411 0.4692052081046576 1.0 0.7809627321887199 26 O60271,Q7Z4H7,O75955,Q96PY6,Q86UY6,Q15154 6 +Microtubule associated complex 0.376123360645732 0.7221066789263749 0.4702288922107871 1.0 0.7809627321887199 50 O15344,O95219,A0MZ66,Q13409,Q66K74,P46821,Q96P70,Q96FJ2,O43237,Q9Y6G9,Q13561,Q15555,P33176,P61163,Q2M1P5,P78559,P29372,O94927,Q8IVD9,Q7Z4H7,P43034,Q9UJW0,Q14203 23 +Endoplasmic reticulum exit site 0.4187924008077514 0.7005160769948082 0.4836050685253485 1.0 0.7913524341952467 19 P04439 1 +Wash complex 0.569144079554175 0.6869945866704829 0.4920861397145191 1.0 0.7969182616615663 4 P47756,P52907 2 +Chaperonin containing t complex 0.4776785714285732 0.6666728900959488 0.5049810989779508 1.0 0.8060285054848148 8 P40227,P49368,P50991,P50990,P48643,P17987,Q99832 7 +Gamma tubulin complex 0.675482912332839 0.6642651131198993 0.5065206455232443 1.0 0.8060285054848148 3 P23258,Q96CW5 2 +Membrane coat 0.3846322461270663 0.6601839969405091 0.5091357605960707 1.0 0.8070152242858861 37 P35606,P42566,P11717,Q9Y678 4 +Equatorial microtubule organizing center 0.6752822341057703 0.6564056308470542 0.5115631684108033 1.0 0.8070152242858861 2 Q96CW5 1 +Postsynaptic endosome 0.6717254526049561 0.6525825082586559 0.514025465218215 1.0 0.8070152242858861 3 Q86Y82 1 +Brca1 a complex 0.6734997029114744 0.650445275965544 0.5154046395819945 1.0 0.8070152242858861 2 Q9NWV8 1 +Sperm annulus 0.6698365527488866 0.6467386001426499 0.5178011364554931 1.0 0.8070152242858861 3 Q16181,Q15019 2 +Intrinsic component of organelle membrane 0.3785141370224854 0.6463407554698467 0.5180586992431133 1.0 0.8070152242858861 140 P42892,Q99595,P01889,O15118,O60830,P13473,O43505,Q9UBM7,P10321,O75844,Q6ZRP7,Q7L0J3,P04439,Q8TCT8 14 +Ragulator complex 0.6720142602495611 0.6454949269229283 0.5186065047869957 1.0 0.8070152242858861 2 Q6IAA8 1 +Messenger ribonucleoprotein complex 0.4925524365819814 0.6413035855427913 0.521325460120825 1.0 0.8071736775223227 6 P67809 1 +Smooth endoplasmic reticulum membrane 0.6699346405228827 0.6385901324691514 0.523089602195852 1.0 0.8080436820876329 2 P56962 1 +Myosin ii complex 0.5534742997191147 0.6343261216754154 0.5258680125278425 1.0 0.8088612393944848 4 P60660,P35579 2 +Signal recognition particle 0.4898869720404732 0.6315497036218964 0.527681161108168 1.0 0.8101145342516338 6 P37108,P61011,P49458,O76094,P09132 5 +Neuron projection 0.4283864177037524 0.6132621430455418 0.5397030206708053 1.0 0.8203127307537988 245 P13591,Q6PCB8,O94898,Q9UJU6,Q92859,Q14118,A0MZ66,P05067,P50897,Q9Y6N7,Q8TAG9,P78310,P16949,Q96A49,Q99828,P05556,Q66K74,P04350,P04792,O75787,P80723,Q13740,P49768,Q13561,P08238,P51114,P19022,Q14247,Q12959,P10586,Q13641,Q9Y4G8,P07900,Q06787,P51790,Q6IBS0,Q8N2K0,P41208,Q7L0J3,Q14651,Q99720,P07197,P78559,O75312,Q9UPT5,Q8N122,Q14444,Q9P273,P43034,Q96QD8,P46060,P35613,Q15375,P52294,Q14168,P29317,Q14203,Q9UQB8,O14786 59 +Haus complex 0.545289930586478 0.607406069124831 0.5435814617526065 1.0 0.8231040448296166 4 Q7Z4H7 1 +Podosome 0.4293056991825117 0.6064165314954333 0.5442381935758667 1.0 0.8231040448296166 11 Q9UJU6,Q14247,O75083,P67936 4 +Cytoplasmic side of membrane 0.3620472778045204 0.6024743918898057 0.5468584041893196 1.0 0.82380824613377 49 Q9H444,P62273,Q9NR28,Q12959,P63096,P15311,Q9UBI6,Q8TCT9,Q9H0H5,P17900,P62942,Q8TCT8,Q96A49 13 +Cortical endoplasmic reticulum 0.6586452762923425 0.6016483298048151 0.5474082509498783 1.0 0.82380824613377 2 P50402 1 +Nuclear outer membrane 0.422069680158628 0.5940608556476211 0.552471410975593 1.0 0.8273508036704872 12 P49768,Q99720,Q9UBM7 3 +Proteasome regulatory particle base subcomplex 0.4420958618636713 0.5719138122457519 0.5673803660987926 1.0 0.8451981982137485 9 P17980,P62333,Q99460,P62195,Q13200,P35998,P62191,P55036 8 +Mismatch repair complex 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.8481509491291145 3 P43246 1 +Elongator holoenzyme complex 0.6405659868535678 0.55887178232048 0.5762492284633167 1.0 0.8490428438177071 3 Q9H9T3 1 +Aminoacyl trna synthetase multienzyme complex 0.4149538278224708 0.5441642486167239 0.5863284514452558 1.0 0.8583848529158545 11 P54136,P14868,P47897,Q12904,Q13155,P07814,Q15046,Q9P2J5,O43324,P56192 10 +Anchored component of synaptic vesicle membrane 0.4826048171275719 0.5336958490705017 0.5935519815019801 1.0 0.8661882983641336 5 P20339,P61020,Q15286,P51149 4 +Super elongation complex 0.6351752822341139 0.5280232426722549 0.5974832040171019 1.0 0.8680205557780171 2 Q03111 1 +Zona pellucida receptor complex 0.4772524531668239 0.5161975394791638 0.6057164486192512 1.0 0.8717311241536503 5 P50991,P49368,P17987,P50990 4 +Smn complex 0.4751709782931979 0.5094571496574776 0.610431826559171 1.0 0.874092521598813 5 Q16637,Q8TEQ6,Q9Y3F4,Q9UHI6 4 +Proteasome regulatory particle 0.3860610259079828 0.5051854108567205 0.6134286162111056 1.0 0.8743337753332092 18 P51665,Q15008,P62333,Q99460,Q9UNM6,Q13200,O43242,P55036 8 +Ciliary tip 0.4327884629752526 0.4942425165747595 0.6211349164155078 1.0 0.8789734478414188 8 Q9BW83,Q15555,Q96FJ2,Q2M1P5,Q9Y366 5 +Polar microtubule 0.608430437520245 0.4690723110950339 0.6390179499249258 1.0 0.896962898129195 3 P23258 1 +Rough endoplasmic reticulum 0.3570122710937864 0.4689642102700048 0.6390952182371596 1.0 0.896962898129195 38 P62266,Q5BJF2,P05067,P49768,Q9UQB8 5 +Endocytic vesicle lumen 0.4402141582391563 0.4590529453469338 0.6461961459315462 1.0 0.9007092593344189 6 Q9Y4L1,P07900,P27797,Q92598,O14964 5 +Cul4 ring e3 ubiquitin ligase complex 0.4217233295071113 0.4541902155850632 0.6496919247658104 1.0 0.9007092593344189 8 Q9Y4B6 1 +Epsilon dna polymerase complex 0.4510782936220284 0.4342818459115924 0.6640837851627137 1.0 0.913739343494561 5 Q9NRF9 1 +Bloc complex 0.5986333927510495 0.4232238943017269 0.6721319150241605 1.0 0.9216849240479942 2 O95295 1 +A band 0.4469223907225782 0.4218823582916042 0.6731108874986282 1.0 0.9216849240479942 5 P04075,P06733,O14974,Q03001 4 +Exocyst 0.4172535744425453 0.4074138730064988 0.6837040394523983 1.0 0.9295942930802524 7 Q8TAG9,Q9UPT5 2 +Kinetochore microtubule 0.3963349442738719 0.3972498726395995 0.6911832083306753 1.0 0.9369372379593598 9 Q9UQN3,Q9Y3E7,Q9H444,P50748,Q8WUX9 5 +Photoreceptor outer segment 0.4185897564348331 0.3907753355378496 0.6959633076324994 1.0 0.9406298766377208 6 P35613,Q15555,P46821 3 +Contractile fiber 0.335038194674546 0.3807378076426675 0.7033978116323047 1.0 0.9464838200640572 57 Q9NYL9,Q16527,P67936,P47756,Q14118,Q16512,P62942,P04792,P35659,P60900,P49768,P06753,P51114,Q05682,Q6IBS0,Q9Y376,Q9UNE7,Q03001,P11166,Q13418 20 +Mcm complex 0.4049390062481496 0.3682970072430748 0.7126517838179218 1.0 0.9547238392289876 7 Q9UJA3,P49736,P33991,P33992,P25205,P33993 6 +Cytoplasmic side of endosome membrane 0.5674390968508723 0.3447488036789889 0.7302832247368121 1.0 0.9576267231835488 2 Q9UL25 1 +Ciliary plasm 0.3541575850445188 0.3435858296864391 0.7311577829123828 1.0 0.9576267231835488 18 Q15019,P04350,Q9BZH6,Q15555,Q10713,Q16181,O95352,Q9UHD8,P10644 9 +Stereocilium bundle 0.3966197780047085 0.3428644029085244 0.731700472652236 1.0 0.9576267231835488 7 Q14651,P43034 2 +Cul2 ring ubiquitin ligase complex 0.4530321046373224 0.3414344452261575 0.7327765478105333 1.0 0.9576267231835488 4 Q92990,Q15369,Q13617 3 +Mitotic spindle microtubule 0.3879769255112734 0.3173461163127805 0.7509809885486054 1.0 0.9760619382414402 7 Q7Z4H7,O94927 2 +Endopeptidase complex 0.3258642390553369 0.3024694981331012 0.7622941821258293 1.0 0.985629544709578 57 P28074,Q13200,O75832,O43292,Q15008,P04792,Q92530,P60900,P49721,Q99436,P54578,P28070,O43242,P25786,Q05086,P28072,P55036,P51665,P25788,Q9BRP4 20 +Golgi transport complex 0.4019078983276023 0.2999999125245428 0.7641772223462426 1.0 0.986208968190144 5 Q14746 1 +Nuclear inner membrane 0.3418411351014755 0.2888838039569772 0.7726702981461575 1.0 0.9874800014289168 21 Q99720,O75844 2 +Protein phosphatase type 2a complex 0.3811003472075888 0.2850868136608407 0.7755776322272818 1.0 0.9874800014289168 6 P63151,Q14738,P30154 3 +Lamellar body 0.538918597742139 0.2829220333302251 0.7772366041783751 1.0 0.9874800014289168 2 Q07065 1 +Tight junction 0.3352864862742299 0.2816549585424881 0.778208094585346 1.0 0.9874800014289168 30 P78310,Q9Y624,P29317 3 +Proximal dendrite 0.5356506238859259 0.2764732789459029 0.7821845804262377 1.0 0.988534379958574 2 P49840 1 +Pseudopodium 0.3662185463597136 0.2736812490325502 0.7843295888838941 1.0 0.9898780328672596 8 P28482,P51809,O43707,P26038,P27361 5 +Cytosolic small ribosomal subunit 0.3327480235997536 0.2673038258728489 0.7892352412902186 1.0 0.9933290863556395 32 P62273,P23396,Q9BY44,P62854,P62851,P62847,P62266,P60866,P25398,P08708,P46783,P08865,P46782,P05198 14 +Female germ cell nucleus 0.5204991087344155 0.2483165934714658 0.8038894612625145 1.0 1.0 2 P29966 1 +Extrinsic component of membrane 0.3157520099052811 0.2347295269614249 0.814418668719894 1.0 1.0 66 P19022,P04062,Q96A49,P63096,Q08431,P15311,Q9UBI6,O14656,Q8N3F8,Q06787,Q9H0H5,O95747,Q9UNF0,P52292,O00459,P62942,Q2M2I8 17 +Node of ranvier 0.4999729286967637 0.234046763093057 0.8149486749706703 1.0 1.0 3 Q14118 1 +Annulate lamellae 0.371003524648304 0.231228048024495 0.8171376411861555 1.0 1.0 5 P63241 1 +Cell division site 0.3293771728170179 0.2307128437661341 0.8175378948091461 1.0 1.0 25 P05556,P35579,Q9NVA2,P35580,Q96GX5,Q9H0H5,Q16512,Q96CW5,Q16181,Q9UHD8,P11233 11 +Intrinsic component of endoplasmic reticulum membrane 0.3168680679635452 0.2276412122605668 0.8199251782295056 1.0 1.0 58 P01889,Q8TCT8,O75844,P04439,P10321 5 +Transcription factor tfiih holo complex 0.3959195301276293 0.222618059313028 0.8238327798386482 1.0 1.0 4 P32780 1 +Carboxy terminal domain protein kinase complex 0.3959195301276293 0.222618059313028 0.8238327798386482 1.0 1.0 4 P32780 1 +Postsynaptic cytoskeleton 0.5008912655971558 0.2161489814762183 0.828871620319694 1.0 1.0 2 P07196 1 +Flotillin complex 0.3450327186198617 0.201311470720213 0.8404550338321957 1.0 1.0 6 Q14254,P35221,P22681,O75955,Q9ULV4 5 +Cleavage furrow 0.3221479318110928 0.1951078846647365 0.8453084901285048 1.0 1.0 20 P05556,P35579,P35580,Q96GX5,Q9H0H5,Q16512,Q16181,P11233 8 +Nucleotide excision repair complex 0.3416664409518045 0.1944744552460698 0.8458043956412047 1.0 1.0 6 P18887 1 +Host cellular component 0.3759860479296655 0.1909327426559753 0.8485782871143639 1.0 1.0 4 O60684 1 +Proteasome regulatory particle lid subcomplex 0.3376971139541838 0.1894788802483578 0.8497175063895901 1.0 1.0 7 Q9UNM6,O43242,Q16186,O00231,O00487,P48556 6 +Trna methyltransferase complex 0.372837426120217 0.1863981477936462 0.852132544824433 1.0 1.0 4 P57081 1 +Exon exon junction complex 0.3700951248513522 0.1825524806779503 0.8551491725833662 1.0 1.0 4 Q92900,Q9Y5S9,P38919 3 +Dna replication preinitiation complex 0.316353887399475 0.180531692519495 0.8567351760848845 1.0 1.0 11 Q9BRT9,Q9UBD5,P49736,P33992,Q9BRX5,P33991,P25205,Q14566,O75419,P33993 10 +Intraciliary transport particle 0.4606240713224387 0.1791419698544797 0.8578262278271933 1.0 1.0 3 Q9Y366,Q9BW83 2 +Intraciliary transport particle b 0.4606240713224387 0.1791419698544797 0.8578262278271933 1.0 1.0 3 Q9Y366,Q9BW83 2 +Myosin filament 0.4603654752683657 0.1788358329161355 0.8580666082210369 1.0 1.0 3 P35579 1 +Proteasome accessory complex 0.3190917239318811 0.1780384130869531 0.8586928083533616 1.0 1.0 21 Q13200,Q06323,Q15008,P17980,Q99460,P61289,O00232,P35998,O43242,P43686,P55036,P51665,P62333,P62195,Q9UNM6,P62191,Q16186,O00231,O00487,P48556 20 +Insulin responsive compartment 0.3395777579542168 0.1750808177935864 0.8610161306427719 1.0 1.0 5 Q6IQ22,Q9Y4I1,P20338,P51153 4 +Elongin complex 0.4528974739970299 0.1702946641240885 0.8647784073842786 1.0 1.0 3 Q15369,Q14241 2 +Cul5 ring ubiquitin ligase complex 0.4528974739970299 0.1702946641240885 0.8647784073842786 1.0 1.0 3 Q15369,Q93034 2 +Anaphase promoting complex 0.3156640857653329 0.1641090918454472 0.869645264594813 1.0 1.0 10 Q16763,Q13042,Q9UJX4,Q12834,Q9H1A4,Q9UJX2,P30260,O60566,Q96DE5 9 +M band 0.4466567607726615 0.1635962196460052 0.8700490208957825 1.0 1.0 3 P04075,P06733 2 +Chaperone complex 0.31582843013446 0.1590561592906504 0.8736246282365987 1.0 1.0 23 Q15185,O95456,P08238,Q9UNE7,Q8WXX5 5 +Centriole 0.3156548521210919 0.1587666086741358 0.8738527574862693 1.0 1.0 25 Q9P2S5,Q9P287,P42858,P23258,Q15154,P41208,Q96CW5,Q14203,Q9Y366 9 +Endoplasmic reticulum tubular network 0.3033373063170445 0.1404101782967 0.8883359164020039 1.0 1.0 12 Q9H6H4,P50402,Q14974,Q9NP72,Q9C0E8,Q15042,P61026,Q9NQC3,Q6NUK4,Q8NHH9,Q12797 11 +Bleb 0.3332342449464897 0.1399576696741282 0.8886934358251315 1.0 1.0 4 Q9Y613,Q96RD7,Q13464 3 +Contractile ring 0.3071295233293542 0.1343955838551513 0.8930897735290746 1.0 1.0 6 O43663,Q14118 2 +Cell tip 0.4118870728083227 0.1331993449896475 0.8940357288542327 1.0 1.0 3 P35241,Q9BTU6 2 +Escrt i complex 0.4080237741456185 0.1305002041559704 0.8961706926310395 1.0 1.0 3 Q99816,Q9UK41 2 +Cd95 death inducing signaling complex 0.3988112927191701 0.1245650989934577 0.9008678601045864 1.0 1.0 3 P49327,Q9UNN5 2 +Filtration diaphragm 0.3978015448603748 0.1192678089312982 0.9050631861756911 1.0 1.0 2 P46940 1 +Cell body membrane 0.3839524517087688 0.1163907982289638 0.9073428277797206 1.0 1.0 3 P20020,P55011 2 +Sperm principal piece 0.3839524517087687 0.1163907982289638 0.9073428277797206 1.0 1.0 3 P08237,Q9BW83 2 +Er membrane insertion complex 0.3747399702823199 0.1121201938055806 0.9107281060387457 1.0 1.0 3 O43765,Q7L5D6 2 +Tubular endosome 0.293697978596905 0.1112691258165767 0.9114029373750384 1.0 1.0 4 O75436,Q9UNH7,Q96QK1 3 +Cation transporting atpase complex 0.3612596553773148 0.1069634169925892 0.9148180022141504 1.0 1.0 2 P54709 1 +Sodium potassium exchanging atpase complex 0.3612596553773148 0.1069634169925892 0.9148180022141504 1.0 1.0 2 P54709 1 +Spindle microtubule 0.3059541819544206 0.1059326116131742 0.9156358193089846 1.0 1.0 32 Q9H444,Q9UQN3,Q9Y3E7,Q15691,O94927,Q7Z4H7,P43034,P06493,P36405,P23258,O43663,Q96CW5 12 +Actomyosin 0.3037162002517597 0.1048228355616026 0.9165163897121484 1.0 1.0 28 Q9Y613,P35579,Q9NVA2,Q13418,P35580,Q8WX93,P67936,Q8WUM4,Q9UJW0,Q96AC1,O43707,Q16181,P06753,Q9UHD8,O95817,Q15942 16 +Mmxd complex 0.3432392273402694 0.1014296514959783 0.9192093993552756 1.0 1.0 3 P18074,Q96T76 2 +Myelin sheath adaxonal region 0.3270944741533064 0.1012316937939879 0.9193665379326847 1.0 1.0 2 Q12846 1 +Vcp npl4 ufd1 aaa atpase complex 0.2810826888756604 0.101073870857264 0.9194918198397588 1.0 1.0 6 Q9UNN5,Q96CS3,P55072,Q92890,Q04323 5 +Actin filament bundle 0.3037712718297204 0.0979595053712762 0.9219644486907246 1.0 1.0 30 Q9Y613,P35579,Q9NVA2,Q13418,P35580,Q16181,Q8WX93,P67936,P12814,Q9UJW0,Q96AC1,O43707,Q14651,P06753,Q9UHD8,O95817,Q15942 17 +Clathrin coat of coated pit 0.2873224999029785 0.0976344395130472 0.922222576364365 1.0 1.0 10 Q9UBC2,P42566,P09496 3 +Meiotic spindle 0.3221396731054999 0.0969827315061937 0.922740108058922 1.0 1.0 3 P54652,O14965 2 +Gap junction 0.2658340767172232 0.0966861649903264 0.9229756270893116 1.0 1.0 5 Q96RD7,Q69YQ0,Q07157,Q16643 4 +Transcription factor tfiid complex 0.2726775902186688 0.0924056015046796 0.9263757891151524 1.0 1.0 6 P18074,P35269 2 +Mitochondrial permeability transition pore complex 0.2545346416889751 0.090357778662241 0.9280029071418896 1.0 1.0 5 P21796,P30405,P05141,Q07812 4 +Rna cap binding complex 0.2790044071202215 0.0901574845847696 0.9281620690699734 1.0 1.0 7 Q06787 1 +Microtubule plus end 0.2707621386385446 0.0661660362805095 0.9472456366189268 1.0 1.0 10 Q14203,Q15691,Q15555,Q03001 4 +Dendrite cytoplasm 0.2681133617149985 0.0640568195450776 0.9489249842058728 1.0 1.0 11 Q14254,Q9UQB8,Q8N2K0 3 +Translation preinitiation complex 0.28077344009 0.0614070933154111 0.9510350033740388 1.0 1.0 15 Q9Y262,O15372,O75821,O75822,Q13347,P55884,P05198 7 +Clathrin vesicle coat 0.2613272477922829 0.0506724650891996 0.9595865181280778 1.0 1.0 10 P09496 1 +Polysome 0.2911499415546867 0.0474998682111439 0.9621148353709548 1.0 1.0 46 P62273,P23396,P62913,P62888,Q99700,P62266,Q06787,P25786,P20290,P63173,P60900,Q6PKG0,P51114,P05198 14 +Protein kinase complex 0.2923456760858783 0.0455618459444443 0.9636594800980308 1.0 1.0 26 P32780,P54619,Q9P287,P06493,Q9Y6K9,Q9Y376,P10644 7 +Microtubule end 0.2362499482694409 0.0139717929338184 0.9888524848188118 1.0 1.0 11 Q14203,Q15691,Q15555,Q03001 4 +Dna polymerase complex 0.2579365946402278 0.0030730979816958 0.9975480264259492 1.0 1.0 15 P49005 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..edcf21d5ab68e68332ee1dfaf7e468cf100495b1 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystroglycan complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner acrosomal membrane", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Super elongation complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Symmetric synapse", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC10", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BRPF1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C1orf131", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG4", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD3", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPAGT1", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL13", "METTL14", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGA", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MLEC", "MLLT1", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFB", "NELFCD", "NENF", "NEO1", "NES", "NF2", "NFS1", "NFU1", "NFYB", "NGDN", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC3", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBRM1", "PBXIP1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF10", "TAF15", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBC1D10A", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNDC15", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2A", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UGGT2", "UHRF1", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WASF2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR75", "WDR77", "WDR82", "WFS1", "WIPI2", "WIZ", "WRAP73", "WRNIP1", "XAB2", "XPC", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB33", "ZC3H14", "ZC3H18", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAK1", "AAMP", "ABCB1", "ABCB6", "ABCC1", "ABHD12", "ACP2", "ACTN1", "ACTN4", "ACTR1A", "ADAM17", "ADGRE5", "ADRM1", "AHCYL1", "AIFM1", "AIMP1", "AIMP2", "AIP", "ALCAM", "ALDOA", "ANAPC1", "ANAPC16", "ANAPC5", "ANP32A", "APLP2", "APOL2", "APP", "ARHGAP1", "ARHGDIA", "ARL3", "ASAH1", "ASPH", "ATG7", "ATL2", "ATP1B3", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATXN2", "AURKA", "B4GAT1", "BABAM1", "BAG3", "BAIAP2", "BASP1", "BAX", "BCAS3", "BCCIP", "BCR", "BSG", "BTF3", "BUB1B", "CAB39", "CALCOCO2", "CALD1", "CALR", "CALU", "CAPRIN1", "CAPZA1", "CAPZB", "CBL", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC45", "CDH2", "CDK1", "CETN2", "CHMP2B", "CHMP3", "CHMP4B", "CHMP7", "CIB1", "CKAP4", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLTA", "COG2", "COLEC12", "COPB2", "COPG1", "COPS2", "COPS5", "COPS6", "COPS7B", "CORO1C", "CSDE1", "CSNK2B", "CSRP2", "CSTB", "CTNNA1", "CTSA", "CTSC", "CTTN", "CUL2", "CUL5", "CXADR", "CYFIP1", "CYP51A1", "DAG1", "DARS", "DBN1", "DBNL", "DCAF1", "DCTN1", "DCTN2", "DCTN4", "DDX20", "DEK", "DHCR24", "DHCR7", "DHRS1", "DIABLO", "DLG1", "DNAJC9", "DNASE2", "DSC2", "DSC3", "DSG2", "DST", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL2", "ECE1", "EEF1E1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELOA", "ELOC", "ELP3", "EMB", "EMD", "ENO1", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERCC2", "ERMP1", "EXOC6", "EXOC7", "EZR", "F11R", "FAF1", "FAF2", "FAM3C", "FASN", "FAT1", "FCGRT", "FERMT2", "FHOD1", "FKBP1A", "FKBP9", "FLOT1", "FLOT2", "FMR1", "FTL", "FUCA1", "FUCA2", "FXR1", "G3BP1", "G3BP2", "GAA", "GABARAPL2", "GAL", "GALNT1", "GBA", "GEMIN5", "GET4", "GGH", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLG1", "GLMN", "GM2A", "GNAI1", "GNG12", "GNS", "GOLIM4", "GPAA1", "GPR107", "GRB2", "GSK3A", "GTF2F1", "GTF2H1", "HAUS5", "HAUS6", "HEXA", "HEXB", "HGS", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGB1", "HMGB2", "HOOK2", "HS2ST1", "HSP90AA1", "HSP90AB1", "HSPA13", "HSPA2", "HSPB1", "HSPH1", "HTT", "HYOU1", "IDH1", "IFT27", "IFT52", "IGF2R", "IKBKG", "ILK", "IMPAD1", "IPO9", "IQGAP1", "IQGAP3", "ITGAV", "ITGB1", "ITM2C", "KARS", "KDELR3", "KIAA0319L", "KIF5B", "KIF7", "KNTC1", "KPNA1", "KPNA2", "KPNA6", "KPNB1", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LARP1", "LARS", "LBR", "LDLR", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LNPEP", "LNPK", "LPCAT2", "LRIG2", "LRP1", "LTA4H", "M6PR", "MAN1A2", "MAN2B1", "MAN2B2", "MAP1A", "MAP1B", "MAP1S", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MASTL", "MBLAC2", "MCAM", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MFGE8", "MICALL1", "MID1", "MIF4GD", "MLLT1", "MMS19", "MOB4", "MPG", "MPP2", "MRC2", "MSH2", "MSN", "MTMR14", "MTPN", "MYH10", "MYH9", "MYL6", "MYO5A", "NAA40", "NAA50", "NAGLU", "NAP1L1", "NAPA", "NCAM1", "NCSTN", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NENF", "NEO1", "NHLRC2", "NISCH", "NOTCH2", "NPC1", "NPC2", "NRBP1", "NRDC", "NRP1", "NSUN2", "NUCB1", "NUCB2", "NUDCD3", "NUFIP2", "OCRL", "ORC2", "ORC3", "OS9", "OXSR1", "P3H1", "PAAF1", "PACSIN2", "PAFAH1B1", "PAK2", "PALLD", "PANX1", "PCDH7", "PCM1", "PCYOX1", "PDAP1", "PDCD6IP", "PDE6D", "PFDN5", "PFKM", "PHAX", "PI4K2A", "PIK3R2", "PIN1", "PKN1", "PLA2G15", "PLBD2", "PLD3", "PLIN3", "PLS1", "PMPCA", "PNP", "POLA2", "POLD2", "POLE3", "PPIF", "PPP1R12A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPT1", "PPT2", "PRC1", "PRCP", "PREPL", "PRIM1", "PRKAG1", "PRKAR1A", "PRRC2C", "PSAP", "PSEN1", "PSMA1", "PSMA3", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME3", "PSMF1", "PSMG1", "PTGES3", "PTK7", "PTPRF", "PYGL", "QARS", "QSOX2", "RAB10", "RAB12", "RAB13", "RAB18", "RAB21", "RAB23", "RAB35", "RAB3GAP1", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAC1", "RACGAP1", "RALA", "RANGAP1", "RAPGEF2", "RARS", "RBM8A", "RCN2", "RDX", "REEP3", "REEP4", "RHOG", "RNASET2", "RNF20", "ROBO1", "ROCK1", "RPL11", "RPL30", "RPL37A", "RPL38", "RPS10", "RPS12", "RPS17", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS29", "RPS3", "RPS5", "RPSA", "RPTOR", "RTN4", "SCAMP1", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SDCBP", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SET", "SEZ6L2", "SGTA", "SHTN1", "SIGMAR1", "SIL1", "SKP2", "SLC12A2", "SLC25A15", "SLC25A5", "SLC2A1", "SLC33A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC6A15", "SLC7A1", "SLK", "SMN1*", "SNAPIN", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX4", "SNX6", "SORT1", "SPAG9", "SPART", "SPECC1L", "SPNS1", "SPPL2A", "SRP14", "SRP19", "SRP54", "SRP72", "SRP9", "STARD3NL", "STMN1", "STOM", "STRAP", "STUB1", "STX12", "STX17", "STX4", "STX7", "STX8", "SURF4", "SV2A", "SYAP1", "SYNGR2", "TBC1D10A", "TCP1", "TENM3", "TFG", "TFRC", "TGOLN2", "TIMM17A", "TIMM17B", "TJP1", "TMEM106B", "TMEM165", "TMEM192", "TMEM30A", "TMEM87A", "TMEM97", "TMOD3", "TOR1A", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPT1", "TRIP11", "TSG101", "TSNAX", "TSPAN3", "TSPAN6", "TTYH3", "TUBB", "TUBB4A", "TUBG1", "TUBGCP3", "TWF2", "TXNDC15", "UBAP2L", "UBE2A", "UBE2N", "UBE2S", "UBE3A", "UBXN1", "UFD1", "UNC119B", "UPF1", "USP14", 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0.203966946010782 1.888961693846712e-09 4.824257395412428e-11 1.7041038794170814e-10 1.2319644324415352e-08 4.346622147922913e-06 +Glycosaminoglycan binding 6 19 2.773307285556801 0.0055489695885462 4.978155339805825 17.45631067961165 0.1337124269810174 0.5629551361084434 2.38360266105164 2.069316753377374 0.9690169198659552 0.3148101721496325 0.0018956552183933 0.0039147102095996 0.0037316022130222 0.0009914642019716 0.0040466728259346 +Amide binding 15 109 2.757261242499104 0.005828776281495 22.521844660194176 102.53398058252426 0.8716704131409604 0.4134472412494542 7.596116055031058 7.786365397071367 1.2519470693533183 0.3815633057547212 4.248009699658382e-05 6.2788056077878775e-06 1.1634210003114152e-08 1.1398531438197734e-05 0.0004422626192199 +Integrin binding 9 24 2.746475879293052 0.006023931542324 6.179611650485437 17.859223300970875 -0.3047919940610424 0.5889748230453251 3.568575338460999 2.9934535983178874 0.818684747476362 0.3137832124263354 0.4683377286563981 1.0 0.1744223041589415 0.0001013686539271 0.0040191895499536 +Amyloid beta binding 3 11 2.740757688749446 0.0061297694453936 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.0033107591961438 0.0140700862732742 0.0004487726521249 0.0121856638082503 0.1040239469578102 +Signaling receptor regulator activity 8 20 2.7347597377765145 0.0062425822877203 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 0.0215059099610276 0.0054233896663051 0.0347449548593629 0.0086869143045309 0.0027070136406106 +Serine hydrolase activity 7 21 2.7142495994013665 0.0066426096597427 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 1.0305390318316204e-07 3.375280228925014e-06 3.74141381298495e-07 1.832311031353461e-05 0.0020289288670538 +Monosaccharide binding 5 28 2.676909800143432 0.0074304635880342 6.529126213592233 27.652912621359224 0.1441354722061465 0.6253240236055831 3.188514919494202 2.1774252770244877 0.8383687523157859 0.3062926587902204 0.005770728097185 0.0013622028220488 0.0096414106757913 0.0007319888819485 0.0013172325096431 +Carboxypeptidase activity 4 12 2.674784147230239 0.0074777378300661 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 1.1913797953523649e-06 5.058405266226161e-06 3.008447980086644e-06 0.0002424536403162 0.0053032680205866 +Metallopeptidase activity 9 41 2.66824239363692 0.0076249225734141 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0040387795117739 0.0006152777977496 0.0011028577372738 0.0001367406142163 0.0004595134276763 +Metalloexopeptidase activity 5 20 2.63704440416876 0.0083631883294243 5.395631067961165 20.067961165048544 0.9825976981990544 0.3457114951896768 2.1791777953827336 1.4039620491256346 0.996651753778752 0.2995335114577974 0.0028215617056553 0.0006503204391585 0.0003611645880796 0.0001788568995486 0.0012811473170246 +Heparin binding 5 13 2.61036440256815 0.0090445820613531 3.4344660194174756 11.91504854368932 0.417671776261347 0.5410412518682232 1.977562601051691 1.5719219414069263 0.9122022863658426 0.3149614964035694 0.005417471152029 0.0195557545343205 0.009062215893767 0.0006474302329561 0.0011303287485076 +Serine type exopeptidase activity 5 7 2.6050352906150747 0.009186479730221 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 1.9955484969117337e-11 2.867520455866967e-10 6.275167299951582e-11 1.578631333778629e-08 9.6474859037805e-07 +Glycolipid binding 3 11 2.538662519319449 0.0111277106231595 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 8.963957464742468e-06 1.1619966216201592e-06 1.879762551529629e-05 0.0006430769062578 0.0079931710216612 +Clathrin binding 2 21 2.5187299032975083 0.0117778965378936 4.686893203883495 19.526699029126213 -0.1590034392061156 0.6172327071271504 4.221020336117202 2.9406369062281223 0.7915289073427865 0.2957122200519332 0.0623838765901622 0.0248568883498602 0.0861587362261736 0.1225340986671723 0.2257163036668415 +Pdz domain binding 7 19 2.486145042866435 0.012913532199571 3.9271844660194177 14.419902912621358 0.5491111169746481 0.4670646684125319 2.189901543859342 2.754676868666853 0.9064591556484958 0.2972085908111159 0.3361355940651335 1.0 0.3898210156705143 0.0332787643737564 0.0026509840530202 +Serine type carboxypeptidase activity 4 5 2.425224027222625 0.0152989426369498 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 3.164979610526897e-11 2.549415016831829e-09 8.206937238409767e-11 8.350760865063851e-09 2.6995663558697725e-07 +Scavenger receptor activity 4 5 2.4014135410905646 0.0163318679628732 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 1.9231390410922443e-06 2.460833692014816e-07 6.154716163450247e-08 5.744803073006659e-06 0.000160552482799 +Phosphatidylserine binding 4 11 2.351868632102867 0.0186793706042256 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.0014713217280779 0.0082126449787597 0.0001488581135043 0.0005176459432172 0.010448798153629 +Serine type endopeptidase inhibitor activity 2 7 2.324756009156196 0.0200850104922922 1.924757281553398 5.526699029126213 0.0879544181827763 0.5160396848581311 1.5490895194100334 1.1133635632531 1.045243956687472 0.329000705737948 0.0004587899988766 0.0038211367015083 0.0007914120786236 0.0104402688493973 0.0624183143373935 +Ceramide binding 1 5 2.259990146733002 0.0238218623757302 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0048180551758565 0.0017760204843955 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Lipid binding 25 149 2.253992251790219 0.0241966554197636 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0009817437493692 0.0002876496183475 0.0014277517427225 0.0002556540962278 0.0487339623116933 +Retromer complex binding 2 5 2.231495060498575 0.0256483543466949 1.7864077669902914 4.62378640776699 0.1266826261911074 0.4322045282144987 1.2199831722291083 0.628387698804986 1.1917576639553151 0.3183570223820515 0.0017758793795144 0.000647621121882 0.0025659780541994 0.0007358710981923 0.0053637976870067 +Signaling receptor binding 42 195 2.2227352901924453 0.0262336547756285 37.12135922330097 173.84466019417476 0.0502519457009315 0.7989055459267156 13.136506240654874 17.387785737284005 0.6384544024115351 0.2942228802179928 0.0507045939813284 0.1628125843979193 0.0128235533920846 0.000258512956808 4.5224144848621513e-05 +Enzyme inhibitor activity 17 75 2.218723037843328 0.0265055727130865 21.356796116504853 71.40776699029126 -0.5842185128112483 0.5211739307306301 10.074546289486891 5.702046801992617 0.9551020163875912 0.3521464969762207 0.0766350277284112 0.2515758385923512 0.0441976218050442 0.0032390983165171 0.0076147227352659 +Palmitoyl protein hydrolase activity 1 5 2.203985573245678 0.0275253586934984 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0040983965897468 0.0015075035399645 0.0058956460302812 0.0333651833289618 0.113339965404402 +Modified amino acid binding 3 21 2.1880592302410986 0.0286652881519202 4.446601941747573 21.354368932038835 0.8157790161756342 0.4133026066112408 2.099367243274066 1.7995833767593454 0.9656025978141096 0.3166170247143811 0.0069121244314848 0.0230307909850112 0.0012175599782738 0.0060702567763488 0.0281454476703931 +Protein lipid complex binding 3 5 2.187263582250703 0.0287232876523912 1.3810679611650485 4.075242718446602 0.904959910455646 0.2381476109936121 0.9668941495076666 1.0318560378441015 1.279214127988033 0.237092245379572 0.0040983965897468 0.0015075035399645 0.000188873280149 0.0001472775053537 0.0020183200628615 +Hexosaminidase activity 3 5 2.1757156048808377 0.0295765326210504 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 4.218158680727945e-05 0.0008300469730069 1.0571166088668371e-06 3.972711663948022e-05 0.0005776438679051 +Peptide alpha n acetyltransferase activity 0 5 2.1650673907944755 0.0303825247815821 1.5946601941747574 4.652912621359223 0.3684306572835352 0.4706661875391733 1.308401021876154 0.7685671084114669 0.9855042784289884 0.3024126131037989 0.0785196824488724 0.0479914252810258 0.0938999510605359 0.2191369015278419 0.3934410105686676 +Coreceptor activity 4 5 2.155367685071525 0.0311330730329655 1.5825242718446602 2.983009708737864 -0.1219149568441634 0.543561837621635 1.0242143268256676 0.8574078511459474 0.9958037451472654 0.3174759955577475 1.0 1.0 0.179062604831997 0.0012358112224234 0.0022722304352638 +Clathrin heavy chain binding 2 5 2.152958121790701 0.0313219699435411 0.9563106796116504 4.172330097087379 0.3682910274765735 0.3434838107739949 1.107360186700709 1.195424695125345 1.3132806864166615 0.2873136636013117 0.0017758793795144 0.000647621121882 0.0025659780541994 0.0007358710981923 0.0003337445501144 +Cytokine binding 4 9 2.1315124921050885 0.0330469444121266 1.9344660194174756 5.871359223300971 -0.200397297123543 0.5251679609353982 1.2971501460018051 1.17846992171863 0.8909842648469317 0.2852942278930233 0.2733967462722031 1.0 0.0558103535730672 0.0024377113202794 0.0396063215160503 +Udp glycosyltransferase activity 3 16 2.1250156933777298 0.0335853034323703 5.111650485436893 16.645631067961165 0.3599735227181602 0.3819150449260511 2.50187506268716 3.5246228662547776 1.2344018614792536 0.2994506580113357 0.4595087541947337 0.3092959809067388 0.1674383799538608 0.1107290245039065 0.3022670069394376 +Peptide antigen binding 4 7 2.120762596593236 0.0339417858007706 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.1154630790463651 0.0711332726649859 1.094486762177302e-05 2.050947898007762e-05 0.0005388274165263 +Sodium ion transmembrane transporter activity 2 7 2.1100311623969703 0.0348556717956127 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 1.0 1.0 1.0 0.0734338910721259 0.3092787829323835 +Antigen binding 4 9 2.102183924675656 0.0355371674239406 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.1715513885376269 0.1070183553885475 6.684645425207902e-05 0.0001958127697586 0.0043704316922178 +Steroid binding 4 21 2.0870130578147887 0.036886954212697 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0073202198372533 0.0239365913087713 0.0121710399777804 0.0066284009542843 0.0888810791636133 +Cell adhesion mediator activity 7 23 2.075217220933097 0.037966407297592 4.604368932038835 19.6504854368932 0.0891352963790946 0.5859939536005466 2.8226339588814735 1.3578876933134028 0.8865562849480031 0.302783824259119 0.2793343331559579 1.0 0.3263246311566628 0.0003819251815083 0.0005820343160061 +Threonine type peptidase activity 4 10 2.0663353604536185 0.0387968247754328 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 1.0 1.0 0.1289666473793992 0.0002865546760543 2.7956915548836924e-05 +Fibroblast growth factor binding 1 6 2.053997366673453 0.0399759465808262 1.577669902912621 4.752427184466019 -0.0086330425964155 0.5211057070882402 1.1746870716402014 0.7612387273633048 0.9409186959441384 0.2976181447770583 0.1154630790463651 1.0 0.009201700056446 0.0506052248933858 0.0338099842169397 +Peptidase activator activity 1 12 2.0534158423026194 0.0400322641283439 3.1359223300970873 11.033980582524272 0.0705051228612008 0.5636696767658763 1.7615005942326416 0.954707640712387 0.8762688899555645 0.2957391193753122 0.0261335387625208 0.141543756104335 0.0368247433715485 0.1746199077901094 0.450369534817547 +Chaperone binding 3 42 2.0519777624899267 0.0401718236072241 9.58252427184466 41.577669902912625 0.0857966897601569 0.6702931427923858 4.408782655318593 3.2622117709628737 0.7810306428207174 0.3113373258659207 0.0318748387409637 0.0650462755169659 0.0096196388866906 0.1539030213852019 0.2334873523449409 +Growth factor receptor binding 6 21 2.0353176150237187 0.0418189248709846 5.233009708737864 16.303398058252426 0.6012049824390195 0.4932334837741021 2.455245557470486 2.477606131434232 0.8745174126419827 0.327387299755004 0.0737029175928528 0.237457799625543 0.1012658374302196 0.1505670934775949 0.0167583931949217 +Extracellular matrix binding 3 6 2.0316970653795408 0.0421843331996965 2.1262135922330097 4.490291262135922 -0.1059374832306895 0.5792352498707123 1.334236348624189 1.2472894544280944 0.8854509277358328 0.3082832623553992 0.1783105780413945 1.0 0.0228441699597423 0.0199432580741765 0.0272826327042602 +Mannose binding 2 6 2.013956242668746 0.0440141277781425 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 0.0017758793795144 0.000647621121882 0.0025659780541994 0.0007358710981923 0.0053637976870067 +Glucosidase activity 1 5 1.9923182337482412 0.0463361523338727 1.674757281553398 4.980582524271845 0.3871275652038076 0.3636983138593921 1.1787123504763262 0.1379870912966203 1.1856385826834483 0.2919762169358068 0.0556262242335954 1.0 0.0666860823201616 0.0115035556388008 0.0423042030727838 +Metalloendopeptidase activity 4 15 1.981625362643877 0.0475211863692714 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.2367426782920286 0.1499686155438198 0.2780273254227372 0.0081443152876 0.0046837779345005 +Lipoprotein particle receptor binding 0 11 1.9781806417908143 0.0479083317535875 3.79126213592233 9.766990291262136 -0.3051327745784666 0.5757747561792527 2.388305114434559 1.4511721642834725 0.8004886806424774 0.305710968477508 0.1509425000049774 0.0937235599037543 0.179062604831997 0.3904027877902372 0.6322714034398937 +Aspartic type peptidase activity 3 5 1.974858458807346 0.0482842127478413 1.558252427184466 4.322815533980583 0.4188215059241264 0.4077056154807147 1.0492738378354591 0.9528515379380612 1.1526921677267827 0.3076869616451514 0.0055914837945719 1.0 0.0080257871552124 0.0445602183527292 0.0037759888499611 +Amino acid transmembrane transporter activity 3 13 1.9605760003049284 0.049928504285424 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 1.0 1.0 1.0 0.0159331781494728 0.0435237537141962 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..15462f263e11338856b0791f1f4efb6fc00aadd8 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 1407, + "title": "Average number of proteins per term", + "value": 17.191186922530207 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0797dc40b95e147ad16454cfec88ae84d9a8330b --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7352f84656177c33cc524fbcef06123121e4e935 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,467 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Molecular transducer activity 0.8214238687761575 3.7957356296884206 0.0001472063034786 0.1870897060943791 0.0935967053468775 42 Q92859,P20645,Q5KU26,P11717,Q9Y6N7,Q9UBG0,P05556,Q99523,Q14108,Q07954,P22466,P48960,O15118,P10586,Q99720,Q8WTV0,P06756,Q92692,Q15375,P29317,O14786 21 +Exopeptidase activity 0.8575669253230445 3.564094562467603 0.0003651143212723 0.4017877502847711 0.0935967053468775 32 Q7Z2K6,O14773,Q9UIQ6,P42785,Q9H3G5,Q9HB40,P10619,O75844,P02786,P53634,Q92820,O75976 12 +Hydrolase activity acting on glycosyl bonds 0.8487245352511721 3.483727983473838 0.0004944817754133 0.5013784705812151 0.0935967053468775 31 P04066,P54802,O75503,Q8IW92,P06280,P10253,Q9BTY2,P07686,O00754,P16278,P17900,Q9Y2E5,P06865 13 +Calcium ion binding 0.6309138137490278 3.428556560218578 0.0006068000829573 0.5743027451469166 0.0935967053468775 96 Q14126,O60245,P01130,Q14118,P67936,P61201,O95302,Q9NPF0,Q9H223,Q9H4M9,P80303,O75071,P04350,Q07954,O14967,Q0IIM8,Q9UM22,Q14517,Q14574,P48960,Q04721,Q7L5N7,Q02818,P19022,Q02487,O94813,Q9Y4G8,P13693,P41208,P42566,O60476,O43852,Q14257 33 +Peptide binding 0.6544246808486052 3.389565993249091 0.0007000335696927 0.62666985426072 0.0935967053468775 77 P55899,P42892,Q9NQX7,P01889,O14773,Q9UIQ6,Q07954,P01130,Q15392,P04439,P55786,Q8WTV0,O43731 13 +Carbohydrate binding 0.7231572159375148 3.3411350773938633 0.0008343661928915 0.6910090403895504 0.0935967053468775 48 Q6PK18,Q13438,O75503,Q5KU26,P10253,P11717,O00754,Q32P28,Q10472,Q9UBG0,Q9Y2E5 11 +Hydrolase activity hydrolyzing o glycosyl compounds 0.8856495146991301 3.326050008264902 0.0008808612330692 0.7105920321791412 0.0935967053468775 23 P04066,P54802,Q8IW92,P06280,P10253,Q9BTY2,P07686,O00754,P16278,P17900,Q9Y2E5,P06865 12 +Exogenous protein binding 0.902131525006449 3.279768854309471 0.0010389216784474 0.7683488392730157 0.0935967053468775 20 P05556,Q14108,P13591,O15118,P01130,P11279,Q8WTV0,Q9Y624,Q92692,P35613,P29317,P02786,P78310,P06756 14 +Phospholipid binding 0.5861091802469991 3.0570589713718466 0.0022352029680243 0.9570814266440344 0.0935967053468775 94 Q14108,Q9Y3E7,O14773,Q9UMY4,Q06481,O95219,P09429,Q08431,Q9UM22,Q9Y4G8,Q8NCC3,Q8N3F8,P50897,Q96L92,P07602,Q8WTV0,Q9Y2I1 17 +Growth factor binding 0.8607172443181651 2.990169550132331 0.0027882263315812 0.9803271111184462 0.0935967053468775 18 Q6YHK3,Q99523,Q92896,Q15375,P06756,P11717,P29317,O43847,O14786 9 +Endopeptidase activity 0.6105269711552859 2.8633927297435875 0.0041913070627523 0.9972866251893996 0.0935967053468775 69 Q8TEY7,P42892,O14773,P78536,Q92542,P28070,P28074,P28072,Q10713,O75844,P60900,P49721,Q99538,P53634,Q8TCT8,O43847,Q4J6C6 17 +Peptidase activity 0.5787650309834831 2.793063921115235 0.0052211373536292 0.999367218182479 0.0954707965089404 122 P42892,O14773,Q9UIQ6,Q6GQQ9,P28074,Q9HB40,P02786,Q99538,O75976,Q4J6C6,Q8TEY7,P78536,P42785,P10619,P60900,P49721,P49768,P53634,Q92820,Q8TCT8,Q9H3G5,Q92542,Q9H8M7,P28070,P28072,Q10713,Q9UJ14,Q7Z2K6,O75844,P55786,O43847 31 +Cargo receptor activity 0.9430929580457168 2.788923495747412 0.0052883555751468 0.999424608863695 0.0954707965089404 10 Q14108,Q07954,P01130,Q08380,Q5KU26,P02786,Q9NPF0 7 +Glycosaminoglycan binding 0.8023510465526106 2.773307285556801 0.0055489695885462 0.9996020332870372 0.0954707965089404 19 Q13685,Q06481,P15586,O94813,P05067,O14786 6 +Amide binding 0.5649698639596947 2.7572612424991036 0.005828776281495 0.9997321497940068 0.0954707965089404 109 P55899,P42892,Q9NQX7,P01889,O14773,Q9UIQ6,Q07954,P55786,P01130,Q9UM22,Q15392,P04439,P07602,Q8WTV0,O43731 15 +Integrin binding 0.7615217778448384 2.746475879293052 0.006023931542324 0.9997967965978404 0.0954707965089404 24 P05556,P09429,P07942,Q08431,Q9Y624,P11047,P78310,Q9Y2I1,P06756 9 +Amyloid beta binding 0.9039149786392672 2.740757688749446 0.0061297694453936 0.9998250704942824 0.0954707965089404 11 P01130,Q9NQX7,Q07954 3 +Signaling receptor regulator activity 0.7879316981665286 2.7347597377765145 0.0062425822877203 0.9998508925227751 0.0954707965089404 20 Q9UMX5,Q92520,P09429,P22466,P26583,Q15375,P05067,Q9NPF0 8 +Serine hydrolase activity 0.777088563085856 2.7142495994013665 0.0066426096597427 0.999915379276512 0.1004962558199786 21 O14773,P42785,Q9H3G5,Q9HB40,P10619,P53634,O75976 7 +Monosaccharide binding 0.7161200718118639 2.676909800143432 0.0074304635880342 0.9999722894471376 0.1073589502745206 28 Q6PK18,O75503,Q5KU26,Q32P28,P11717 5 +Carboxypeptidase activity 0.8711912311345287 2.674784147230239 0.0074777378300661 0.9999740855968624 0.1073589502745206 12 P10619,Q9HB40,O75976,P42785 4 +Metallopeptidase activity 0.6487381666641453 2.66824239363692 0.0076249225734141 0.9999789661238068 0.1083663238464015 41 Q7Z2K6,P42892,Q9UIQ6,Q10713,O75844,P02786,P55786,O75976,O43847 9 +Metalloexopeptidase activity 0.7682858016586303 2.63704440416876 0.0083631883294243 0.9999926181545896 0.1153628037205895 20 Q7Z2K6,Q9UIQ6,O75844,P02786,O75976 5 +Heparin binding 0.8393143913706215 2.61036440256815 0.0090445820613531 0.999997193649798 0.1209719575884393 13 Q13685,Q06481,O94813,P05067,O14786 5 +Serine type exopeptidase activity 0.977806145742614 2.6050352906150747 0.009186479730221 0.9999977057681076 0.1209719575884393 7 O14773,P42785,Q9HB40,P10619,O75976 5 +Glycolipid binding 0.8549779619539656 2.538662519319449 0.0111277106231595 0.9999998546980832 0.1436393472182153 11 P07602,O14773,P50897 3 +Clathrin binding 0.7386843830693595 2.5187299032975083 0.0117778965378936 0.9999999424068516 0.1506500038983303 21 P01130,Q07954 2 +Pdz domain binding 0.7442054612744384 2.486145042866435 0.012913532199571 0.9999999885774326 0.1593801737262846 19 P78536,Q9Y624,Q9Y4G8,Q9UQB8,P51790,Q9BXI6,P78310 7 +Serine type carboxypeptidase activity 0.980672019030626 2.4252240272226255 0.0152989426369498 0.9999999996204256 0.1778976222329625 5 P10619,Q9HB40,O75976,P42785 4 +Scavenger receptor activity 0.9741302408563756 2.4014135410905646 0.0163318679628732 0.9999999999133072 0.1868206359655498 5 Q14108,Q08380,Q07954,Q5KU26 4 +Phosphatidylserine binding 0.8108431959774581 2.351868632102867 0.0186793706042256 0.999999999996994 0.1991051093950415 11 Q14108,Q08431,Q8WTV0,Q06481 4 +Serine type endopeptidase inhibitor activity 0.902767752019023 2.324756009156196 0.0200850104922922 0.9999999999996 0.2062745238150017 7 P05067,Q06481 2 +Ceramide binding 0.935629672838313 2.259990146733002 0.0238218623757302 0.999999999999998 0.2347189837709925 5 P07602 1 +Lipid binding 0.5394407206829438 2.253992251790219 0.0241966554197636 0.9999999999999988 0.2347909943145344 149 Q9BQE5,Q9Y3E7,O14773,Q06481,O95219,P61916,P11717,P50897,O95772,P07602,Q9Y2I1,Q14108,Q9UM22,Q8NCC3,O15118,Q08431,P28070,Q9Y4G8,Q8WTV0,P04062,Q9UMY4,P09429,Q8N3F8,Q96L92,A6NIH7 25 +Retromer complex binding 0.9279437440379856 2.231495060498575 0.0256483543466949 1.0 0.2438326659851341 5 Q99523,P11717 2 +Signaling receptor binding 0.5602429736102301 2.2227352901924453 0.0262336547756285 1.0 0.2471215426087823 195 Q9BQE5,Q9UMX5,O95219,O94898,O00560,P26583,P67870,P06280,O00170,Q9Y6K9,P05067,P62942,Q9NPF0,P78310,Q9Y2I1,P05556,Q8TEY7,P78536,Q07954,P22466,P60520,Q13740,P49768,P60983,Q92520,Q92542,Q08431,O94813,Q9Y4G8,Q92896,P11047,O00459,P04439,P11233,P06756,O75312,P01889,P04062,P09429,P07942,Q9Y624,Q15375 42 +Enzyme inhibitor activity 0.518771972451114 2.218723037843328 0.0265055727130865 1.0 0.2471215426087823 75 O94992,Q6YHK3,Q8N122,O43924,P04792,Q9C0C9,Q06481,P62913,P04080,O94813,Q9BTT0,P61201,Q92530,P05067,Q01105,P10644,P60983 17 +Palmitoyl protein hydrolase activity 0.9205457028966446 2.203985573245678 0.0275253586934984 1.0 0.2547906558010024 5 Q9UMR5 1 +Modified amino acid binding 0.6758324527040867 2.1880592302410986 0.0286652881519202 1.0 0.2557826944741427 21 Q14108,Q08431,Q06481 3 +Protein lipid complex binding 0.9160591609861832 2.187263582250703 0.0287232876523912 1.0 0.2557826944741427 5 P01130,Q5KU26,Q8WTV0 3 +Hexosaminidase activity 0.9129653840152684 2.1757156048808377 0.0295765326210504 1.0 0.2600886337363621 5 P17900,P54802,P06865 3 +Coreceptor activity 0.9075230449003776 2.155367685071525 0.0311330730329655 1.0 0.2649139822866445 5 P05556,O14786,P06756,Q92692 4 +Clathrin heavy chain binding 0.9068793284850234 2.152958121790701 0.0313219699435411 1.0 0.2649139822866445 5 P01130,Q07954 2 +Transmembrane receptor protein kinase activity 0.9631391200951238 2.15141780079594 0.0314432374142641 1.0 0.2649139822866445 4 Q15375,P11717,P29317 3 +Transmembrane receptor protein tyrosine kinase activity 0.9631391200951238 2.15141780079594 0.0314432374142641 1.0 0.2649139822866445 4 Q15375,P11717,P29317 3 +Cytokine binding 0.8042535945765699 2.1315124921050885 0.0330469444121266 1.0 0.2767681594515606 9 P05556,Q6YHK3,P06756,O14786 4 +Udp glycosyltransferase activity 0.7009210230029179 2.1250156933777298 0.0335853034323703 1.0 0.2779677760549708 16 P07686,O43505,P06865 3 +Peptide antigen binding 0.8496952097941026 2.120762596593236 0.0339417858007706 1.0 0.2792753954484464 7 P55899,P01889,P04439,Q15392 4 +Sodium ion transmembrane transporter activity 0.8469368926988932 2.1100311623969703 0.0348556717956127 1.0 0.2841357899941116 7 Q9H2J7,Q96QD8 2 +Antigen binding 0.7971538281683922 2.1021839246756557 0.0355371674239406 1.0 0.2873608883073821 9 P55899,P01889,P04439,Q15392 4 +Steroid binding 0.6571253708681662 2.0870130578147887 0.036886954212697 1.0 0.2949896717702196 21 Q14108,P61916,P04062,O15118 4 +Cell adhesion mediator activity 0.6443650836312623 2.0752172209330975 0.037966407297592 1.0 0.3001052531893933 23 Q14126,P05556,Q02487,Q6PCB8,P35613,Q08722,P78310 7 +Threonine type peptidase activity 0.7670073433697402 2.0663353604536185 0.0387968247754328 1.0 0.3036208581596564 10 P49721,P28070,P28072,Q9UJ14 4 +Fibroblast growth factor binding 0.8496824395474915 2.053997366673453 0.0399759465808262 1.0 0.3088620536358709 6 Q92896 1 +Peptidase activator activity 0.7293904691405144 2.0534158423026194 0.0400322641283439 1.0 0.3088620536358709 12 P05067 1 +Chaperone binding 0.554368106053545 2.0519777624899267 0.0401718236072241 1.0 0.3088620536358709 42 P02786,Q14108,P53634 3 +Growth factor receptor binding 0.6476406472543461 2.0353176150237187 0.0418189248709846 1.0 0.3182512493670101 21 P78536,O95219,Q92542,O00560,P05067,P49768 6 +Dipeptidyl peptidase activity 0.9313157161118673 2.0350543720156065 0.0418454023687966 1.0 0.3182512493670101 4 P42785 1 +Extracellular matrix binding 0.8438917746525417 2.0316970653795408 0.0421843331996965 1.0 0.3188745994525919 6 P05556,O94813,P06756 3 +Solute sodium symporter activity 0.92805426932667 2.0230595114030714 0.0430670122613949 1.0 0.320784867635582 4 Q96QD8 1 +Xenobiotic transmembrane transporter activity 0.9279923533181708 2.022831676680316 0.0430905046077647 1.0 0.320784867635582 4 P08183,P33527 2 +Gamma catenin binding 0.9272600729395728 2.0201367333992093 0.0433692065275654 1.0 0.3211603872857086 4 Q14574,Q02487 2 +Mannose binding 0.8392945333246397 2.013956242668746 0.0440141277781425 1.0 0.3225481081511192 6 O75503,P11717 2 +Acetylglucosaminyltransferase activity 0.9251094360621926 2.0122182967407465 0.0441969305911813 1.0 0.3225481081511192 4 P07686,P06865 2 +Volume sensitive anion channel activity 0.9229096168126756 2.004113166304277 0.0450579393466106 1.0 0.3267861889725832 4 Q9C0H2 1 +Proteoglycan binding 0.9215219976218766 1.9989976442693187 0.0456086087514049 1.0 0.3290836539139833 4 P10586,O94813,Q07954 3 +Glucosidase activity 0.8643116704115295 1.9923182337482417 0.0463361523338727 1.0 0.3323087343799706 5 P10253 1 +Metalloendopeptidase activity 0.6798820244921614 1.981625362643877 0.0475211863692714 1.0 0.3376884304119444 15 P42892,Q10713,O75844,O43847 4 +Aspartic type peptidase activity 0.8597246020864461 1.974858458807346 0.0482842127478413 1.0 0.3396794366810637 5 P49768,Q8TCT8,Q92542 3 +Amino acid transmembrane transporter activity 0.6962113979019753 1.9605760003049284 0.049928504285424 1.0 0.3433555876325591 13 Q9H2J7,P08195,Q96QD8 3 +Hormone binding 0.8245707568151579 1.956922261070953 0.0503566088676001 1.0 0.3433555876325591 6 P42892 1 +Cell cell adhesion mediator activity 0.6314242954669786 1.9462114335914025 0.0516293470601194 1.0 0.3486931726385557 21 Q14126,Q02487,Q6PCB8,P35613,Q08722,P78310 6 +Collagen binding 0.7594555361741967 1.9448259505628132 0.0517959296954215 1.0 0.3486931726385557 9 P05556,Q9UBG0 2 +Peptidase regulator activity 0.5747588193371127 1.9291316714594935 0.0537145180616163 1.0 0.356492108078746 33 Q6YHK3,Q06481,Q92530,P05067,P53634 5 +Organic acid transmembrane transporter activity 0.6126449119981845 1.9255889000243336 0.0541557257982467 1.0 0.3577328929489823 24 P30825,P08183,Q96QD8,Q9H2J7,P08195 5 +Glycosphingolipid binding 0.8975459418664522 1.9102623607536688 0.0560994414372708 1.0 0.3688407201039257 4 P07602 1 +Inorganic anion transmembrane transporter activity 0.6177608329219539 1.8965397533669877 0.0578887085150283 1.0 0.3788344785146275 22 P33527,P51790,Q9BXP2,Q15043,Q9C0H2 5 +Beta n acetylhexosaminidase activity 0.8914089354966263 1.887447227517506 0.0591001980103018 1.0 0.382280776825131 4 P17900,P06865 2 +Sphingolipid binding 0.766614804549999 1.8813059608283251 0.0599303106338886 1.0 0.382280776825131 8 P07602 1 +Lysophosphatidic acid binding 0.9937611408199646 1.8776235142724296 0.0604326866440732 1.0 0.382280776825131 2 O14773 1 +Protein tyrosine kinase activity 0.6438466385437404 1.8771810248711849 0.0604932872892334 1.0 0.382280776825131 17 Q15375,O14786,P11717,P29317 4 +Protease binding 0.5695810017150089 1.8740086283267752 0.0609292358756552 1.0 0.382280776825131 32 P05556,P01130,Q13438,P04080,P07602,P06756 6 +Low density lipoprotein particle receptor activity 0.989007724301842 1.8588919748613963 0.0630424518487777 1.0 0.382280776825131 2 P01130 1 +Efflux transmembrane transporter activity 0.8836164314367637 1.8584200936989432 0.0631093810071754 1.0 0.382280776825131 4 P08183,P33527 2 +Cytokine activity 0.798007620225974 1.853222249149665 0.0638505099317563 1.0 0.382280776825131 6 Q92520 1 +Thiolester hydrolase activity 0.653808611838723 1.852170473878416 0.0640013472065688 1.0 0.382280776825131 15 Q9UMR5 1 +G protein coupled receptor activity 0.8814012920495973 1.8501571874324425 0.0642908974999252 1.0 0.382280776825131 4 P48960,P22466 2 +Endopeptidase regulator activity 0.5825730078010336 1.8472396738173071 0.0647124117529944 1.0 0.382280776825131 27 Q6YHK3,Q92530,P05067,Q06481 4 +Sterol binding 0.6452042491809485 1.845106024090136 0.0650221170806217 1.0 0.382280776825131 16 Q14108,P61916,O15118 3 +Galactoside binding 0.98425430778372 1.8401454229308472 0.0657468901068949 1.0 0.382280776825131 2 P06280 1 +Channel inhibitor activity 0.7944725154272195 1.839345957112688 0.0658643175205095 1.0 0.382280776825131 6 Q96PU5,Q9UKS6,P62942 3 +Cysteine type endopeptidase activity 0.5907309861169682 1.8284950784092369 0.0674752836374359 1.0 0.382280776825131 25 Q99538 1 +G protein alpha subunit binding 0.8734553763801279 1.8204765237696152 0.0686864681940164 1.0 0.382280776825131 4 P80303,P11717 2 +Tau protein binding 0.6164443505316891 1.817047771882563 0.0692097988508351 1.0 0.382280776825131 19 Q02790,P08238,Q13526,P07900,Q14203,Q99538,P78559 7 +Beta galactosidase activity 0.977421271538919 1.81317233862047 0.0698052447719372 1.0 0.382280776825131 2 P16278 1 +Rna strand annealing activity 0.8175257324098062 1.8129575051116305 0.0698383757850895 1.0 0.382280776825131 5 Q15056,P23588,Q06787 3 +Apolipoprotein binding 0.871184736798768 1.8119834070325112 0.0699887604067139 1.0 0.382280776825131 4 Q07954 1 +Beta 2 microglobulin binding 0.9738562091503278 1.799088386004971 0.0720047005082886 1.0 0.382280776825131 2 P55899 1 +Cholesterol binding 0.6621784736284952 1.7985778821807945 0.0720854786558597 1.0 0.382280776825131 13 Q14108,P61916,O15118 3 +Peptide receptor activity 0.9735591206179448 1.7979143957563388 0.0721905744745756 1.0 0.382280776825131 2 P22466 1 +Pattern recognition receptor activity 0.9732620320855624 1.7967403559848198 0.0723768490513092 1.0 0.382280776825131 2 Q5KU26 1 +Transforming growth factor beta binding 0.9720736779560312 1.7920437054247478 0.0731259653133906 1.0 0.382280776825131 2 Q6YHK3 1 +Laminin binding 0.8118491082176984 1.7910113328623938 0.0732914764048544 1.0 0.382280776825131 5 P05556,O94813 2 +Aspartic endopeptidase activity intramembrane cleaving 0.8644470868014228 1.7867525357016565 0.0739774938553048 1.0 0.382280776825131 4 P49768,Q8TCT8,Q92542 3 +Protein binding involved in heterotypic cell cell adhesion 0.7650707458552722 1.7859548320491694 0.0741065717593203 1.0 0.382280776825131 7 Q14126,Q02487,P78310 3 +Ether hydrolase activity 0.8101958153680843 1.784612589428523 0.0743241779445114 1.0 0.382280776825131 5 P34913,P07099 2 +Epoxide hydrolase activity 0.8101958153680843 1.784612589428523 0.0743241779445114 1.0 0.382280776825131 5 P34913,P07099 2 +Phosphatidylcholine binding 0.7629678959115502 1.7774955893500295 0.0754867358824449 1.0 0.382280776825131 7 Q14108 1 +L amino acid transmembrane transporter activity 0.6999955021475067 1.7744954370510595 0.0759812361818226 1.0 0.382280776825131 10 P30825,P08195,Q96QD8 3 +Palmitoyl coa hydrolase activity 0.7759356147984289 1.7663057237758135 0.077344571848029 1.0 0.382280776825131 6 P50897 1 +Mannosidase activity 0.7755580326342945 1.7648132264980927 0.0775951609954219 1.0 0.382280776825131 6 Q9Y2E5,O00754 2 +Ephrin receptor activity 0.9649435531788472 1.7638479097838546 0.0777575888288795 1.0 0.382280776825131 2 Q15375 1 +Amino acid sodium symporter activity 0.964349376114082 1.761497081077649 0.0781543066124859 1.0 0.382280776825131 2 Q96QD8 1 +Organic acid sodium symporter activity 0.964349376114082 1.761497081077649 0.0781543066124859 1.0 0.382280776825131 2 Q96QD8 1 +Lipid transporter activity 0.601986858618877 1.759124019968516 0.0785564459062924 1.0 0.382280776825131 20 Q9NV96,P33527,O15118,P08183,P61916,P17900 6 +Flippase activity 0.9619726678550218 1.752092042769014 0.0797579823113694 1.0 0.382280776825131 2 P08183 1 +Gtpase inhibitor activity 0.7722845723244232 1.751866284199285 0.0797968032326601 1.0 0.382280776825131 6 O94813 1 +Dna n glycosylase activity 0.8001972953768767 1.7458496025797403 0.0808370891340624 1.0 0.382280776825131 5 P13051,P23396 2 +Aromatic amino acid transmembrane transporter activity 0.9598930481283424 1.743860433052184 0.0811834294887439 1.0 0.382280776825131 2 P08195 1 +Hydrolase activity acting on ether bonds 0.7531833944325891 1.7380531595324296 0.0822014472904468 1.0 0.382280776825131 7 P34913,P07099 2 +Omega peptidase activity 0.5554268754945249 1.729116717281909 0.0837882077676142 1.0 0.382280776825131 29 Q8TEY7,Q9H8M7,Q9HBH5,Q6GQQ9,Q9UJ14,Q92820 6 +Axon guidance receptor activity 0.955436720142603 1.726214695627618 0.0843087951952337 1.0 0.382280776825131 2 Q15375 1 +Anion channel activity 0.6580192136517848 1.722891940897343 0.0849080680057079 1.0 0.382280776825131 12 Q9C0H2 1 +Galactosidase activity 0.9777117384843984 1.7204840738434557 0.0853444861888086 1.0 0.382280776825131 3 P16278,P06280 2 +Anion transmembrane transporter activity 0.4951811569836247 1.7173674090453137 0.0859120625629452 1.0 0.382280776825131 51 P11166,P33527,P30825,Q96QD8,P51790,Q9BXP2,O00400,P08195,Q15043,Q9C0H2 10 +C x3 c chemokine binding 0.9527629233511596 1.7156231888251694 0.0862310314955099 1.0 0.382280776825131 2 P06756 1 +Gdp dissociation inhibitor activity 0.7913602027903531 1.711498605225627 0.0869891084428087 1.0 0.3824802361844746 5 P52565,P55010,P43487 3 +Lipoprotein particle receptor activity 0.973551263001486 1.7055608181273278 0.0880898797256493 1.0 0.3843443525258017 3 P01130,Q07954 2 +Low density lipoprotein particle binding 0.973551263001486 1.7055608181273278 0.0880898797256493 1.0 0.3843443525258017 3 P01130,Q5KU26 2 +Secondary active transmembrane transporter activity 0.5675401800791817 1.689515294597956 0.0911207233618125 1.0 0.3932725698468412 25 Q96QD8,P51790,Q9BXP2,O00400,Q9H2J7,P08195,Q15043 7 +Threonine type endopeptidase activity 0.7197531120729921 1.6870023905956415 0.0916028922826137 1.0 0.3941445548673931 8 P49721,P28070,P28074,P28072 4 +Phosphatidic acid binding 0.8363410106542304 1.6810610874797012 0.0927510496725321 1.0 0.3978680697843069 4 Q8N3F8,Q9Y4G8 2 +Growth factor activity 0.7540266752547395 1.679408955286288 0.0930723691747972 1.0 0.398032897960303 6 Q9NPF0,Q9UMX5,P60983 3 +Aminopeptidase activity 0.6145063964850558 1.6536870564392383 0.0981911139037245 1.0 0.4132121391892944 15 Q9UIQ6 1 +Ganglioside binding 0.9588436376730576 1.652739740771258 0.0983838426641177 1.0 0.4132121391892944 3 P07602 1 +Insulin like growth factor binding 0.9549874167200236 1.6388751435508722 0.1012392653777962 1.0 0.4192901221115258 3 P11717 1 +Alcohol binding 0.6026558485056995 1.6255983534715734 0.1040351257160647 1.0 0.4267563320189595 16 Q14108,P61916,O15118 3 +G protein coupled receptor binding 0.5332417883756985 1.6171246672776969 0.1058513732291388 1.0 0.4304418558768738 31 Q8TEY7,P22466,P63096,O00560,Q9Y4G8,O43776,P48681,P46934,Q96J02,P11233 10 +Solute cation symporter activity 0.6627341405744563 1.6085538832613029 0.1077139250547258 1.0 0.4340232566408352 10 Q9H2J7,Q9BXP2,O00400,Q96QD8 4 +Four way junction dna binding 0.7331198391215661 1.5959647034370747 0.1104966740213508 1.0 0.4391774586102844 6 O15347,P09429 2 +Proline rich region binding 0.7311765989158812 1.5881851637153572 0.1122444749666651 1.0 0.441675423849353 6 P07737,Q9UQB8 2 +Sulfur compound binding 0.4820651226803928 1.5859629934956094 0.1127477045369684 1.0 0.441675423849353 46 Q13685,Q07954,Q06481,P15586,O94813,P05067,O14786 7 +Laminin 1 binding 0.9197860962566868 1.5848138387056534 0.1130086372322438 1.0 0.441675423849353 2 O94813 1 +Extracellular matrix structural constituent 0.9387815750371472 1.5805521913297622 0.1139804645145856 1.0 0.443012468431 3 P07942,Q08431 2 +Metalloaminopeptidase activity 0.626630117885497 1.5740965305250714 0.1154651345532828 1.0 0.4438782631597514 12 Q9UIQ6 1 +Abc type xenobiotic transporter activity 0.93496847478651 1.5668182130015853 0.1171571889867246 1.0 0.4469345615684454 3 P08183 1 +Neutral amino acid transmembrane transporter activity 0.7255856862088694 1.5657817834792551 0.1173997122905232 1.0 0.4469345615684454 6 Q96QD8 1 +Hexosyltransferase activity 0.5112050780940828 1.5652224213471977 0.117530766013024 1.0 0.4469345615684454 36 O43505,P07686,P04062,P06865 4 +Sulfatide binding 0.9328433406775885 1.5591624623764937 0.1189579328815528 1.0 0.4494499774724007 3 O14773 1 +Voltage gated chloride channel activity 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.4494499774724007 2 P51790 1 +Chemoattractant activity 0.8036610868034322 1.5574154432759917 0.1193718819081679 1.0 0.4494499774724007 4 P26583,P09429 2 +Chemokine binding 0.9322436849925708 1.5570020398009952 0.119470001119174 1.0 0.4494499774724007 3 P05556,P06756 2 +Channel regulator activity 0.5683109111847022 1.5514729147202917 0.1207883933305402 1.0 0.453198051776187 19 Q9UKS6,O15400,Q9UNK0,Q12959,Q9UEU0,P46934,Q96PU5,P62942 8 +Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication 0.7479678013660205 1.5417450766100718 0.1231355534242828 1.0 0.4543359786857823 5 Q02487 1 +Gated channel activity 0.5983060079143467 1.5414883430916568 0.1231979778267877 1.0 0.4543359786857823 14 P51790,Q9C0H2 2 +Phospholipid transporter activity 0.7163506785147368 1.528711862434171 0.1263358902429114 1.0 0.4547188619237223 6 P08183 1 +Lipopolysaccharide binding 0.7017234667928632 1.528595876643206 0.1263646588572675 1.0 0.4547188619237223 7 P28070,Q8WTV0,P09429 3 +Chloride channel inhibitor activity 0.7952263298902316 1.5254003746264195 0.1271592653833102 1.0 0.4552495837005534 4 O15400,Q9UEU0 2 +Symporter activity 0.6149203119699024 1.5181208001362765 0.1289839484707409 1.0 0.4595021801446602 12 Q9H2J7,Q9BXP2,O00400,Q96QD8 4 +Toxic substance binding 0.9022578728461113 1.5152268322391762 0.1297149701987354 1.0 0.4597203099990448 2 P34913 1 +5 3 exodeoxyribonuclease activity 0.8989898989899022 1.5022553541598642 0.1330311740326322 1.0 0.4670552161979028 2 Q8IV08 1 +Vitamin transmembrane transporter activity 0.6938558006663593 1.4963132475387533 0.1345720445015832 1.0 0.4686028544339976 7 P33527,P04062 2 +5 3 exonuclease activity 0.6923246972347955 1.4900241454341094 0.1362178873230313 1.0 0.4686028544339976 7 Q8IV08 1 +Tap binding 0.7331567589347477 1.4834687830272677 0.1379499044401531 1.0 0.4707576358985523 5 P04439,P01889 2 +Tetrapyrrole binding 0.5624084504349561 1.4804170320134216 0.138761987421498 1.0 0.4707576358985523 18 Q9NPF0,Q9NP58,Q16850 3 +Quaternary ammonium group binding 0.6157803037796292 1.4753807353536457 0.1401102116845778 1.0 0.4707576358985523 11 Q14108 1 +Phosphatase inhibitor activity 0.7030923008543419 1.4753650922047954 0.1401144150230253 1.0 0.4707576358985523 6 Q01105,Q9BTT0 2 +Chloride channel regulator activity 0.7310933029568147 1.4753395696668448 0.1401212731769627 1.0 0.4707576358985523 5 O15400,Q9UEU0 2 +L ornithine transmembrane transporter activity 0.8906714200831873 1.4692462890909888 0.1417659992309912 1.0 0.4715478981513111 2 P30825 1 +Amino acid cation symporter activity 0.9062094652728117 1.4631608338507782 0.1434233750452913 1.0 0.4737011471566312 3 Q96QD8 1 +Gtpase activating protein binding 0.7255634550951341 1.4535434955351416 0.1460729123314061 1.0 0.4782349541680393 5 P36405,Q13526,P07437 3 +Deoxyribonuclease activity 0.5472274630411905 1.4504024798402964 0.1469463159819475 1.0 0.4788066891813703 20 O00115,Q8IV08,Q9UQ84,P23396 4 +Cysteine type peptidase activity 0.4636616883193666 1.4427352505549471 0.1490950651536446 1.0 0.4836718021432398 47 Q8TEY7,Q9H8M7,Q6GQQ9,Q99538,P53634,Q92820 6 +Cyclin dependent protein serine threonine kinase regulator activity 0.7221993787674179 1.4402769422642854 0.1497890622047912 1.0 0.4844901391313593 5 O94992 1 +Transferrin receptor binding 0.7209942521446076 1.4355232451878075 0.1511380492311562 1.0 0.4855258017907771 5 Q9Y6K9,O60749,O95219 3 +Anion cation symporter activity 0.8947401997785696 1.4218164868473018 0.1550795321379019 1.0 0.4884970769597463 3 Q9BXP2 1 +Fibronectin binding 0.8946306958331529 1.4214218182191771 0.1551941673070409 1.0 0.4884970769597463 3 P06756 1 +Atpase coupled inorganic anion transmembrane transporter activity 0.8913085845394766 1.4094493709503342 0.1587023341289128 1.0 0.4896802283319746 3 P33527 1 +Phosphoprotein binding 0.501916976232192 1.408179283141292 0.1590779891133424 1.0 0.489765275016352 31 P28482,O15344,P62258,Q8IWS0,Q02790,Q13526,P43034,P06400,P07737,P62993,P46108,O00459,P11717,P46934,P29372,Q92541,Q9NWS0 17 +Antiporter activity 0.6002928036278924 1.4027382014516103 0.1606949212215158 1.0 0.4916007533896219 11 P51790,P08195 2 +Oxidized dna binding 0.6839131923816194 1.3979771276341386 0.1621199357304794 1.0 0.4916007533896219 6 P43246,P18887,P23396 3 +Enzyme activator activity 0.4322907932100349 1.392125196759867 0.1638844894276325 1.0 0.4943771445350883 118 Q07960,P55201,Q9UJU6,Q9H6U6,Q12834,P43487,P05067,Q9BXI6,Q8TC07,P07602,O43169,Q0IIM8,Q86X10,P10619,Q9H0H5,Q9H6Z4,P17900,P53634,P35269,Q6IN85,P60983,Q02750,Q9Y4G8,Q86VI3,P52565,Q9Y376,Q13177,Q8N122,Q9H2M9,P46060,P11274,O14786 32 +Rage receptor binding 0.8863124155621875 1.3914479193784386 0.1640896421449085 1.0 0.4943771445350883 3 P09429 1 +Protein serine threonine kinase inhibitor activity 0.6288003053669072 1.3805529223875426 0.1674164668641014 1.0 0.4969495117893605 9 O94992,Q8N122,P04792,P10644,Q99828 5 +Camp binding 0.8820970311246417 1.376264409722726 0.1687397873351297 1.0 0.4969495117893605 3 Q9Y4G8 1 +Calcium channel inhibitor activity 0.8669043374925742 1.3750703344448791 0.1691096403537733 1.0 0.4969495117893605 2 P62942 1 +Cyclic nucleotide binding 0.7551757981954976 1.3730635702875975 0.1697325849806334 1.0 0.4969495117893605 4 Q9Y4G8 1 +Single stranded dna exodeoxyribonuclease activity 0.7541371893521512 1.369110049015289 0.1709648775890333 1.0 0.4969495117893605 4 Q8IV08 1 +Solute cation antiporter activity 0.8757671088120448 1.3534746706087943 0.1759040366481437 1.0 0.5030426413901182 3 P51790 1 +Map kinase kinase activity 0.6978887897710285 1.3442967265062689 0.1788524537044777 1.0 0.5082124114600147 5 Q02750,P28482,P36507,Q96KB5 4 +Protein kinase a catalytic subunit binding 0.6704046507873898 1.3433563489125648 0.1791566141323151 1.0 0.5082124114600147 6 P10644 1 +Sterol transporter activity 0.6544123803026389 1.333739985861884 0.1822890853880405 1.0 0.511926295143481 7 P61916 1 +Active ion transmembrane transporter activity 0.4507263429954958 1.329252846761109 0.183764565254066 1.0 0.5121125096491874 44 Q96QD8,P51790,Q9BXP2,O00400,Q9H2J7,P08195,Q15043 7 +Adrenergic receptor binding 0.6887399902927434 1.3081529296675782 0.1908214437376791 1.0 0.5254814696512893 5 Q9Y4G8,P46934,O14745 3 +Beta catenin binding 0.5312692366583555 1.308079033969166 0.1908465039032045 1.0 0.5254814696512893 18 P19022,P78310,Q13526,Q8WZA0 4 +Voltage gated channel activity 0.5792546729686441 1.3036292786543835 0.1923600129088065 1.0 0.5262020728320854 11 P51790,P06756 2 +Ubiquitin like protein conjugating enzyme activity 0.6291951782946174 1.3034368645291028 0.1924256577728846 1.0 0.5262020728320854 8 P49459,Q9Y3C8,Q9C0C9,P61088 4 +Coa hydrolase activity 0.6286406176687891 1.3010668098245677 0.1932355872693278 1.0 0.5262020728320854 8 P50897 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.6861766188928785 1.2980263379987491 0.1942782846315291 1.0 0.5277018271748293 5 Q9UHG3,Q6ZRP7 2 +Chemokine receptor binding 0.6852057917621861 1.294191254842526 0.1955993667348641 1.0 0.528898029147643 5 Q96J02,P48681 2 +Mismatch repair complex binding 0.7318668252080811 1.2843717507604695 0.1990119123637728 1.0 0.5303215164693719 4 Q9UJA3,P43246,P52701 3 +Fad binding 0.5903588220859575 1.2805070758089014 0.200366857823184 1.0 0.531917299919283 10 Q8NB78,Q15392 2 +Sulfotransferase activity 0.8413547237076692 1.2742444497677192 0.2025767966887661 1.0 0.533360788318159 2 Q7LGA3 1 +Supercoiled dna binding 0.6763333206892637 1.2591494580042637 0.2079763531729714 1.0 0.5401887622772377 5 P09429,P23396 2 +Nucleobase containing compound kinase activity 0.5104246567662336 1.2548091616321972 0.209548045955942 1.0 0.5419744497426662 21 O94992,Q5KU26,Q9BZX2 3 +Nucleoside triphosphatase regulator activity 0.392973448319619 1.2457936162420618 0.2128401738308609 1.0 0.5454756367577802 87 Q07960,P43487,Q9BXI6,Q8TC07,P80303,Q0IIM8,O00410,Q86X10,Q9NR50,O95373,P55010,Q9H0H5,Q9H6Z4,Q02818,P24534,O94813,Q9Y4G8,Q86VI3,P52565,Q9H2M9,O43924,A4D1U4,P29692,P46060,Q13144,O14786 26 +Lys48 specific deubiquitinase activity 0.6681782940716219 1.226960390045769 0.2198374788199819 1.0 0.5497881875393587 5 Q9H8M7 1 +Transition metal ion transmembrane transporter activity 0.8401188707280838 1.2255072038504875 0.2203841775211075 1.0 0.5497881875393587 3 Q9HC07,Q15043 2 +Manganese ion transmembrane transporter activity 0.8401188707280838 1.2255072038504875 0.2203841775211075 1.0 0.5497881875393587 3 Q9HC07,Q15043 2 +Mitogen activated protein kinase kinase binding 0.8276886512180663 1.220590325337765 0.2222411712160403 1.0 0.552461710072383 2 Q13526 1 +Voltage gated anion channel activity 0.6387588416009429 1.215257612950478 0.2242678529102084 1.0 0.5535874895520408 6 P51790 1 +Ubiquitin like modifier activating enzyme activity 0.5897519155522836 1.2080102654840548 0.2270433137604857 1.0 0.5573544262023286 9 Q8TBC4,O95396,Q9UBT2,O95352,Q13564 5 +Endodeoxyribonuclease activity 0.5420462153002392 1.207953486647298 0.2270651541766306 1.0 0.5573544262023286 13 O00115,Q9UQ84,P23396 3 +Glycosyltransferase activity 0.4294501856189645 1.169248242859661 0.2423036293323945 1.0 0.582771293112272 49 O43505,P07686,P04062,P06865 4 +Actin monomer binding 0.6517961134727117 1.162396474706813 0.2450744546023626 1.0 0.5884296205213724 5 P07737,Q6IBS0 2 +Kinase regulator activity 0.428417201522046 1.1548573405439448 0.2481488511756218 1.0 0.5897726918988173 47 O94992,Q8N122,Q9H9T3,P04792,P54619,Q9P287,P60983,Q02750,P67870,Q9Y376,O00459,Q13177,P08238,P10644,Q99828 15 +Protein self association 0.5311323969287497 1.1533812947519322 0.2487539156411142 1.0 0.5902137593710755 13 P53634 1 +High density lipoprotein particle binding 0.8151693979807844 1.136574603452834 0.2557161618535502 1.0 0.6016599326554265 3 Q8WTV0 1 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.8042186571598386 1.1290832719163009 0.2588627072948704 1.0 0.6025037727794043 2 O94992 1 +Sodium channel inhibitor activity 0.8039215686274557 1.127931143560965 0.2593489999716007 1.0 0.6025037727794043 2 Q96PU5 1 +Phosphatidylinositol 3 phosphate binding 0.6044387575610266 1.1270776441899697 0.2597096544519108 1.0 0.6025037727794043 7 Q9UMY4,O95219 2 +Transforming growth factor beta receptor binding 0.6899524375743087 1.1255477466492296 0.260356996339643 1.0 0.6025037727794043 4 P62942,Q9UNH7,Q8WUH2 3 +Hydrolase activity hydrolyzing n glycosyl compounds 0.5708200139157318 1.1242206076363384 0.260919449155111 1.0 0.602654306373814 9 P29372,P13051,P23396 3 +Translation initiation factor activity 0.4457659616463924 1.1134756567275677 0.2655041976423047 1.0 0.6032994164730037 37 Q14240,O60841,O75821,Q13347,Q92905,P60842,O43583,Q9NR50,P55010,O00303,P23588,Q9Y262,Q04637,P06730,P55884,P05198,P49770,Q9BY44,O15372,P20042,O75822,Q15056,Q13144 23 +Cytoskeletal anchor activity 0.5996859509670598 1.107459163342484 0.2680954587206359 1.0 0.605474013515144 7 Q8TD16,O00560,Q9UQB8 3 +Ribosomal small subunit binding 0.536713674507734 1.1024439978380214 0.2702686925537372 1.0 0.6057625460222553 11 Q15056,P23588,P13051 3 +14 3 3 protein binding 0.6820341774151035 1.0957297646799886 0.2731970529563776 1.0 0.6068958089814208 4 Q8N122 1 +Epidermal growth factor receptor binding 0.5804704633257978 1.0951070206112858 0.2734697533007966 1.0 0.6068958089814208 8 P62993,O60749,O95219,Q99700 4 +Ephrin receptor binding 0.579684953400755 1.091754176226138 0.2749411654096567 1.0 0.6072876290916595 8 P62993,Q15375,O00560 3 +Monooxygenase activity 0.5628424207282283 1.0889430142564138 0.2761790161355881 1.0 0.6077146633927867 9 Q16850 1 +Calcium channel regulator activity 0.6742653487228498 1.0665577247264544 0.2861715991196498 1.0 0.6166055742133956 4 Q9UKS6,P62942 2 +Protein carboxyl o methyltransferase activity 0.791976225854384 1.0546340593571888 0.2915927204181294 1.0 0.620682235443734 3 Q9H993,O60725 2 +Phosphotyrosine residue binding 0.5383445374401635 1.0427420222640655 0.2970677898427427 1.0 0.6285329027199082 10 P28482,Q06124,P46108,P62993,P07737,O00459,P27361 7 +Ubiquitin protein transferase inhibitor activity 0.5664798838962883 1.0354685391114191 0.3004501516361013 1.0 0.6293274901577475 8 P62829,P60866,P62913 3 +Annealing activity 0.5330060650747473 1.0184030745844823 0.3084864416617547 1.0 0.6372470516529652 10 Q15056,P23588,Q06787 3 +Tpr domain binding 0.6144314626847693 1.0160995806386737 0.3095819687432493 1.0 0.6372470516529652 5 P08238,P07900 2 +Metal ion transmembrane transporter activity 0.4479963513347994 1.0137594107606511 0.31069756747259 1.0 0.6372470516529652 28 Q96QD8,Q9HC07,Q9BXP2,Q9H2J7,P08195,Q15043,P06756 7 +L ascorbic acid binding 0.5600686376614576 1.0082077732943384 0.3133547269518058 1.0 0.6388783752536855 8 Q6PK18,Q32P28 2 +Tropomyosin binding 0.7697563874034494 0.9967649794260228 0.3188786007130186 1.0 0.6455571096449169 2 Q05682 1 +Ccr chemokine receptor binding 0.7740501671640794 0.9919487969714156 0.3212225035482405 1.0 0.6484362446088586 3 P48681 1 +Camp dependent protein kinase regulator activity 0.7723370756346991 0.9859932226774796 0.3241364386108554 1.0 0.6498015246654172 3 P10644 1 +N acetyltransferase activity 0.473106556676376 0.9825501088755676 0.3258289094781803 1.0 0.6503721052337178 18 Q86UY6 1 +Structural constituent of postsynapse 0.6027436446032118 0.9707754592017976 0.3316601057501211 1.0 0.6529471952122052 5 P07196,Q12959,P12814 3 +Insulin receptor binding 0.5663837425122963 0.9706389112948708 0.3317281220885353 1.0 0.6529471952122052 7 O60749,O95219 2 +Potassium channel regulator activity 0.577731978743778 0.969662211052716 0.3322148924037029 1.0 0.6529471952122052 6 Q96PU5,Q12959 2 +Translation factor activity rna binding 0.4027733354845864 0.961108737601333 0.3364974968286074 1.0 0.6584867566590411 54 Q14240,O60841,O75821,Q13347,Q92905,P60842,O00178,O43583,Q9NR50,P55010,O00303,P24534,P23588,P15170,Q9Y262,P62495,Q04637,P63241,P06730,P26641,P55884,P05198,P49770,Q9BY44,O15372,Q7Z2Z2,P20042,O75822,Q15056,P29692,Q13144 31 +Iron ion binding 0.4499491950573597 0.9592380619953148 0.3374388299533679 1.0 0.6586755382412476 25 Q6PK18,Q16850,Q32P28,P02792 4 +Scaffold protein binding 0.4577625329421582 0.9572653054466485 0.3384333622732387 1.0 0.6595231865906467 22 Q8IWS0,Q02750,P07900,Q16543,P46108,Q96RD7,P07602,Q9UQB8 8 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.643984802891715 0.9538684100567008 0.3401502556640976 1.0 0.6610378587284328 4 P06493 1 +Protein folding chaperone 0.4414985771195809 0.9252364846606465 0.3548429091984046 1.0 0.6765094488376089 26 P48723,P04792,O14967,O14656,P07900,P08238 6 +Protein phosphorylated amino acid binding 0.4661364220068697 0.9197739451294932 0.3576909015943621 1.0 0.6810163715064513 17 P28482,P62258,Q13526,P27361,Q06124,P46108,P07737,P62993,O00459,P46934,Q92541 11 +Map kinase phosphatase activity 0.7468805704099861 0.9107830600030652 0.3624096898097062 1.0 0.6881382369261224 2 Q99956 1 +Dynactin binding 0.562229501085187 0.9081328164101944 0.363808054231741 1.0 0.6894948493917343 6 Q8TD16,Q9UNH7,P43034 3 +Sulfur compound transmembrane transporter activity 0.50628589387909 0.8971869112578458 0.3696191882489836 1.0 0.6943313723181842 10 O00400 1 +Cation transmembrane transporter activity 0.3771735595776014 0.8884547758207121 0.3742961720840996 1.0 0.695954630715955 75 P30825,Q13423,Q93050,Q96QD8,P51790,Q9BXP2,O00400,O43772,Q9H2J7,P08195,P06756 11 +Dynein light intermediate chain binding 0.5551925668262442 0.880390799410952 0.3786476389967657 1.0 0.7001150706160072 6 Q96ED9 1 +Translation activator activity 0.5740391079154031 0.8608210427416088 0.3893366135799918 1.0 0.70880410027435 5 A9UHW6 1 +Non membrane spanning protein tyrosine phosphatase activity 0.7296494355317932 0.847276892730634 0.3968408031953321 1.0 0.717803633954956 2 P24666 1 +Mutlalpha complex binding 0.7316493313521555 0.8467712005060888 0.3971226636223917 1.0 0.717803633954956 3 P43246,P52701 2 +Nedd8 specific protease activity 0.7277559609748684 0.8337105628367564 0.4044441044058291 1.0 0.7231672841284936 3 Q92905 1 +Lipase activity 0.4463321203686619 0.8328598641816498 0.4049237677414374 1.0 0.7231672841284936 18 Q8IV08,Q8NHP8,Q8NCC3 3 +Phosphatidylinositol bisphosphate phosphatase activity 0.5643160074436783 0.8241290829302287 0.4098662167607547 1.0 0.7260645339154894 5 Q10713,Q8NCE2 2 +N acyltransferase activity 0.4364349452265644 0.818061690984903 0.4133219621635864 1.0 0.7296175034528513 21 Q86UY6 1 +Inorganic molecular entity transmembrane transporter activity 0.3605519327736137 0.8139953116914111 0.415647636780377 1.0 0.7317710660556018 82 P33527,P51798,Q13423,Q93050,Q15043,Q96QD8,Q9HC07,P51790,Q9BXP2,O00400,Q9H2J7,Q9C0H2,P08195,P06756 14 +Translation initiation factor binding 0.4463419685302617 0.811889942769125 0.4168547858502123 1.0 0.7317710660556018 17 O75312,Q13144,P20042,Q04637,Q06787,P55010,P06730,Q6PKG0,O00303,P55884 10 +Procollagen proline dioxygenase activity 0.6042778816480451 0.8096264615426092 0.4181548948889153 1.0 0.7317710660556018 4 Q32P28 1 +Peptidyl proline dioxygenase activity 0.6042778816480451 0.8096264615426092 0.4181548948889153 1.0 0.7317710660556018 4 Q32P28 1 +Glucocorticoid receptor binding 0.7183600713012529 0.8063589493978842 0.4200359094100878 1.0 0.7335228890126323 2 Q02790 1 +Dynein heavy chain binding 0.7194650817236263 0.8060767213953842 0.4201986130377979 1.0 0.7335228890126323 3 O43237,Q13409 2 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.7185919121321823 0.8031811124043853 0.4218700607187207 1.0 0.7355280984278066 3 Q8NCE2 1 +Macrolide binding 0.5242563054841056 0.8005903115569787 0.4233688613893576 1.0 0.7355399964537557 7 P62942,Q02790,Q9Y680 3 +Fk506 binding 0.5242563054841056 0.8005903115569787 0.4233688613893576 1.0 0.7355399964537557 7 P62942,Q02790,Q9Y680 3 +Translation regulator activity 0.3616227349454237 0.7962659429978242 0.4258774762676938 1.0 0.7376500853125998 80 P19525,O75821,O60841,P04818,P27635,Q13347,P49588,Q92905,O00178,O43583,Q9Y6M1,Q9NR50,P55010,A9UHW6,O00303,P51114,P24534,P23588,Q9Y262,P15170,P62495,Q06787,P63241,P35268,P06730,P26641,P55884,P05198,P49770,O15372,Q7Z2Z2,P20042,O75822,P29692,Q15056,Q6PKG0,Q13144 37 +Intramembrane lipid transporter activity 0.5976712180521917 0.7861496399274961 0.4317798255542984 1.0 0.740774008663962 4 P08183 1 +Translation termination factor activity 0.7121212121212175 0.7840059558689866 0.4330366155792924 1.0 0.740774008663962 2 P15170 1 +Dna binding bending 0.553500271389603 0.7837172751518217 0.4332060236497268 1.0 0.740774008663962 5 O15347,P09429 2 +Cxcr chemokine receptor binding 0.7115270350564523 0.7818872469070832 0.43428084053136 1.0 0.740774008663962 2 Q96J02 1 +Protein transmembrane transporter activity 0.4602508015858672 0.7710926482410012 0.4406520179189899 1.0 0.7443580686004014 12 Q99595 1 +Nadp binding 0.4348886005793533 0.7693311111974822 0.4416967726733398 1.0 0.7443580686004014 18 Q13423,Q14739,Q9UBM7 3 +Protein homodimerization activity 0.4164460189693354 0.752444141897102 0.4517840093716618 1.0 0.7594505390512882 187 Q14108,P42892,P34913,Q06481,O94813,Q9P273,Q9Y624,P27105,P06280,O95772,P16278,P02786,P07602,Q8TCT8,Q13137 15 +Semaphorin receptor activity 0.7022497495784948 0.7495433491839877 0.4535297811549375 1.0 0.7614754201491611 3 O14786 1 +Organic anion transmembrane transporter activity 0.4013254586092774 0.7458346563676709 0.4557673019077453 1.0 0.7619863761729592 34 P33527,P30825,Q96QD8,O00400,P08195 5 +Map kinase activity 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.7705529598581369 2 P28482 1 +Phospholipid transfer activity 0.6954842543077897 0.7253931782935685 0.4682108568799159 1.0 0.7730214964151716 2 Q9Y255 1 +Atpase coupled intramembrane lipid transporter activity 0.6946869600416447 0.725103836413988 0.4683883310202901 1.0 0.7730214964151716 3 P08183 1 +Insulin like growth factor receptor binding 0.6941772178793766 0.7234658801375379 0.4693937090382545 1.0 0.7730214964151716 3 P46108 1 +Hyaluronic acid binding 0.6939988116458764 0.7202350947449135 0.4713802593826954 1.0 0.7738996790565374 2 O75330 1 +Calcium ion transmembrane transporter activity 0.43159810835836 0.7159593414082418 0.4740164548768488 1.0 0.777320689990357 16 Q9HC07,P08195,P06756 3 +Type i transforming growth factor beta receptor binding 0.6897473997028242 0.7092826217285741 0.4781491104758217 1.0 0.7813656195580502 3 P62942,Q9UNH7 2 +Kinase inhibitor activity 0.4143001276779557 0.6886321264042644 0.4910547986756302 1.0 0.7930142950931335 21 O94992,Q8N122,P04792,Q99828,P10644,P60983 6 +Transporter activity 0.4087101834221777 0.6788861584678227 0.4972099965770324 1.0 0.7963751221098492 185 Q9NV96,O96000,P30825,Q13423,P61916,Q9BXP2,O00400,Q8NE01,Q8IXU6,Q9C0H2,Q9BSK2,P51798,P08183,Q93050,Q9HC07,O43772,P17900,Q9H2V7,Q15043,P33527,O15118,P51790,Q7L0J3,Q8WTV0,P06756,P11166,Q99595,P04062,O60830,Q96QD8,O43678,Q9H2J7,P08195 33 +Nucleoside diphosphate kinase activity 0.5245316681534407 0.6780135308480538 0.4977631140717675 1.0 0.7963751221098492 5 P15531,P23919,P30085,P27144 4 +Beta 2 adrenergic receptor binding 0.6798541763282713 0.6779505211655644 0.4978030656125149 1.0 0.7963751221098492 3 P46934 1 +Macromolecule transmembrane transporter activity 0.4345476163814308 0.6761707688519659 0.4989322292584242 1.0 0.7963751221098492 13 Q99595 1 +Glucosyltransferase activity 0.4446949822713963 0.6747547057767359 0.4998316216951792 1.0 0.7963751221098492 11 P04062 1 +Kinesin binding 0.4550346517228332 0.6702450262316842 0.5027016050929214 1.0 0.7978848185105618 10 O60271,A0MZ66,O14656 3 +Phosphatidylinositol binding 0.3663293875432611 0.6652969912006805 0.5058605546586148 1.0 0.7988168354710112 60 Q9UMY4,O95219,Q06481,Q96L92,Q8WTV0,Q9Y2I1 6 +Gtpase activator activity 0.3672956008551569 0.647342261017474 0.5174104557744288 1.0 0.8065834239699928 50 Q07960,Q14C86,P43487,Q9BXI6,Q8TC07,Q8N6T3,Q4KMP7,Q0IIM8,Q86X10,Q9H0H5,Q9H6Z4,P50395,Q9Y4G8,O60343,Q86VI3,P52565,Q9H2M9,Q01968,O00429,P46060,P11274,O14786 22 +1 4 alpha oligoglucan phosphorylase activity 0.6683506686478466 0.6421554219407294 0.5207722738737668 1.0 0.8096426401551269 3 P06737,Q13126 2 +Molecular function regulator 0.4451823506283386 0.641052973259801 0.5214882663813942 1.0 0.8098609169962712 316 P54619,Q06481,Q07960,P19525,P55201,P17931,P43487,P05067,P07602,Q9NPF0,Q8TC07,Q99828,P22466,O00410,P10619,O95373,P17900,P53634,P63151,Q6YHK3,Q12959,Q02750,O94813,P54578,O43242,P07900,P52565,O43924,Q14558,O60256,A4D1U4,P29692,P46060,Q15375,P11274,Q69YN2,Q01105,O14786,Q9H9T3,Q13200,O14737,P07737,P42771,P46934,Q4KMP7,P80303,Q15008,Q9UEU0,Q9H173,P55010,Q92530,Q02818,O94992,Q92520,Q9BTT0,Q9Y4G8,Q86VI3,O00459,Q96PU5,P10644,Q8N122,P09429,P04080,Q9UMX5,P78318,P26583,P67870,Q9BXI6,P62942,Q0IIM8,Q86X10,Q9NR50,Q9H6Z4,Q6IN85,P60983,P24534,O95429,O15400,Q9Y376,P11233,Q9C0C9,P62913,Q9P287,Q9UJU6,Q12834,P61201,P04792,O43169,P60866,Q9H0H5,Q86XL3,P08238,P35269,Q9UKS6,Q13177,Q9H2M9,P51858,Q13144,Q9H6U6 99 +Carboxylic acid binding 0.3795134956265022 0.6355861595742466 0.5250461928215857 1.0 0.8126952621561838 38 P07602,P11717 2 +Phosphatase regulator activity 0.4045813111778361 0.6324422289960082 0.5270979471464039 1.0 0.8139576572256293 21 P19525,P78318,P17931,Q9BTT0,Q86XL3,Q01105,P35269,Q6IN85 8 +Endonuclease activity 0.3756030396606045 0.6205339604818252 0.5349063026856724 1.0 0.8204983159709731 39 Q99598,O00584,O00115,Q9UQ84,P18887,P23396 6 +Thyroid hormone receptor binding 0.4768495597480513 0.6170427986239047 0.5372064965219385 1.0 0.8204983159709731 7 Q15648,P32780 2 +Actinin binding 0.4767008772804956 0.6164858505009237 0.5375739077093102 1.0 0.8204983159709731 7 Q04206,Q16527,Q14118 3 +Snap receptor activity 0.421883786765696 0.6159941035037586 0.537898411473908 1.0 0.8204983159709731 13 O15400,O15498,Q9UNK0,Q9UEU0,Q86Y82,Q12846,P56962 7 +Eukaryotic initiation factor 4e binding 0.6593428151649198 0.6146400683794433 0.5387924469314302 1.0 0.8204983159709731 3 Q6PKG0 1 +Sodium channel regulator activity 0.4848745952032739 0.613326113459826 0.5396607300850189 1.0 0.8208677267347261 6 Q96PU5,P46934 2 +Fructose 6 phosphate binding 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.8284081063224603 3 Q01813,P08237 2 +Phosphofructokinase activity 0.6526002971768214 0.5943589310356788 0.5522720708816402 1.0 0.8284081063224603 3 Q01813,P08237 2 +Fructose binding 0.6511144130757811 0.5899270907766382 0.5552395308262996 1.0 0.8310872551836208 3 P17858,P08237 2 +Histone acetyltransferase binding 0.4768426569023327 0.5844641193638461 0.5589080986598944 1.0 0.8348022237945557 6 Q9H6U6,Q15650 2 +Ubiquitin ubiquitin ligase activity 0.4674204105920994 0.5820060142376672 0.5605626298317969 1.0 0.835020433452974 7 Q14139,P61086,O95155,Q13356,O95071,Q9UNE7 6 +Protein kinase activity 0.3338592794194408 0.5754120700180906 0.565012642976523 1.0 0.835020433452974 85 P54619,Q9UHY1,P19525,Q96KB5,Q15118,P67870,P11717,Q9Y4B6,P25440,Q2M2I8,Q9H2G2,Q13308,Q05682,Q02750,O95747,Q9P289,Q13177,Q13418,O14976,Q96PY6,P06493,Q15375,P11274,P29317,Q96SB4,O14786 26 +Protein transporter activity 0.4063028361301107 0.5750412594101263 0.5652633931772186 1.0 0.835020433452974 15 Q99595 1 +Ap 2 adaptor complex binding 0.6485442661913328 0.569411974412891 0.5690765924623049 1.0 0.8392984964302548 2 Q2M2I8 1 +Small protein activating enzyme binding 0.6421991084695406 0.5636321263928419 0.5730045181573984 1.0 0.8433235952379284 3 Q9UBE0,Q9UBT2 2 +Abc type transporter activity 0.4292481428748324 0.5609839652398023 0.5748084682798937 1.0 0.8433321322938587 10 P08183 1 +Enzyme regulator activity 0.4239311150888719 0.5478864801470804 0.5837698526703419 1.0 0.8520375339286006 249 P54619,Q07960,P19525,P55201,Q06481,P17931,P43487,P05067,Q8TC07,P07602,Q99828,O00410,P10619,O95373,P17900,P53634,P63151,Q6YHK3,Q02750,O94813,P54578,O43242,P07900,P52565,O43924,Q14558,O60256,A4D1U4,P29692,P46060,P11274,Q69YN2,Q01105,O14786,Q9H9T3,Q13200,O14737,P42771,Q4KMP7,P80303,P55010,Q92530,Q02818,O94992,Q9BTT0,Q9Y4G8,Q86VI3,O00459,P10644,Q8N122,P04080,P78318,P67870,Q9BXI6,Q0IIM8,Q86X10,Q9NR50,Q9H6Z4,Q6IN85,P60983,P24534,Q9Y376,Q9C0C9,P62913,Q9P287,Q9UJU6,Q12834,P61201,P04792,O43169,P60866,Q9H0H5,Q86XL3,P08238,P35269,Q13177,Q9H2M9,Q13144,Q9H6U6 79 +Proteasome binding 0.4092622163525663 0.536779790417367 0.5914197330381867 1.0 0.8593064106382748 12 O95456 1 +Phosphatase activator activity 0.482503073170652 0.5333610355061527 0.5937836844598319 1.0 0.8601737582622058 5 Q6IN85 1 +Lipase activator activity 0.6357694592988793 0.5298303974755593 0.5962295275158171 1.0 0.8610147492774282 2 Q12846 1 +Phosphate ion binding 0.4792673810093771 0.5227571368351476 0.60114327134975 1.0 0.8636219667669065 5 P00491,Q8NCH0 2 +S adenosyl l methionine binding 0.6330956625074355 0.5217226119992989 0.6018634784977546 1.0 0.8636219667669065 2 Q99873 1 +Ion transmembrane transporter activity 0.3450077144353927 0.5213233437565743 0.6021415418609348 1.0 0.8636219667669065 110 P11166,P33527,P51798,P30825,Q13423,Q93050,Q15043,Q96QD8,Q9HC07,P51790,Q9BXP2,O43772,O00400,Q9H2J7,Q9C0H2,P08195,P06756 17 +Cyclin dependent protein kinase activity 0.4775498067201988 0.5171634395148083 0.6050420714175335 1.0 0.8660164745518512 5 P24941,P11802,P21127,P06493 4 +Peroxisome targeting sequence binding 0.6298276886512264 0.5118992051950619 0.6087215544580522 1.0 0.8695139361649539 2 Q9NXR7 1 +Protein serine threonine kinase activator activity 0.4312949431581804 0.4887709578645421 0.6250038611712674 1.0 0.884262618634248 8 Q02750,P36507,Q9Y376,P46940 4 +Intramolecular transferase activity phosphotransferases 0.5071343638525442 0.4881911224551678 0.6254144720749502 1.0 0.884262618634248 4 P36871,O95394,P18669 3 +Demethylase activity 0.4065351493599795 0.4689400953447092 0.6391124556388903 1.0 0.8931969976797154 10 Q16850 1 +Cytokine receptor binding 0.3709321888918592 0.4682993217102874 0.6395705534251843 1.0 0.8931969976797154 25 P78536,O00560,Q8WUH2,Q9Y5K6,P62993,O43776,P30046,P48681,Q8WXW3,P62942,Q9UNH7,Q96J02 12 +Translation elongation factor activity 0.3894257671102196 0.4672179331418199 0.6403439645383997 1.0 0.8931969976797154 13 P24534,O00178,P26641,P63241 4 +Proteasome activating activity 0.4417013682331861 0.4639204316906498 0.6427047538244819 1.0 0.8943998999505185 6 P17980,P62333,P62195,P35998,P62191 5 +Nitric oxide synthase regulator activity 0.6058408845970267 0.4621793240864078 0.6439527290498659 1.0 0.8944141063900901 3 P08238 1 +L lactate dehydrogenase activity 0.608734402852059 0.4508866029133952 0.6520712796609458 1.0 0.8985938202575423 2 P00338 1 +Lactate dehydrogenase activity 0.608734402852059 0.4508866029133952 0.6520712796609458 1.0 0.8985938202575423 2 P00338 1 +Amide transmembrane transporter activity 0.4274766055896996 0.4411267777130742 0.6591212187328241 1.0 0.9022360750756384 7 O00400 1 +Dna secondary structure binding 0.3899359048385562 0.4399467962119508 0.6599756416672637 1.0 0.9022360750756384 11 O15347,P09429 2 +Phosphoserine residue binding 0.4249266134442968 0.4326174348149651 0.6652927211499908 1.0 0.9022360750756384 7 Q92541,Q13526,P46934 3 +Active transmembrane transporter activity 0.3273216327929744 0.4323327378816057 0.6654995965163808 1.0 0.9022360750756384 79 P33527,O96000,P08183,Q96QD8,P51790,Q9BXP2,O00400,O43678,Q9H2J7,Q15043,P08195 11 +Atpase binding 0.358973627877216 0.4315094974032505 0.6660979484231462 1.0 0.9022360750756384 30 Q92542,P60520,Q93050,P49768,Q9NUM4 5 +Amp binding 0.4236382756319803 0.4283431330051048 0.6684013202031807 1.0 0.9022360750756384 7 P06737,P07741 2 +Atpase regulator activity 0.4130344162756572 0.4235699604044147 0.6718794668519046 1.0 0.9022360750756384 8 Q9H173 1 +Adenyl nucleotide exchange factor activity 0.4130344162756572 0.4235699604044147 0.6718794668519046 1.0 0.9022360750756384 8 Q9H173 1 +Ubiquitin like protein conjugating enzyme binding 0.4004748486585304 0.4122062912761901 0.6801882262821677 1.0 0.907899255966585 9 P23396 1 +Structural constituent of muscle 0.4184864763478848 0.4114220015982955 0.6807631236991807 1.0 0.907899255966585 7 P60660,Q14118,P67936 3 +7s rna binding 0.4180303481106963 0.4099372545151094 0.6818519759231847 1.0 0.9079490966350124 7 P37108,P61011,P49458,Q9UHB9,O76094,P09132 6 +Zinc ion binding 0.3515982161735553 0.4070958100336543 0.6839376206555734 1.0 0.9079490966350124 133 Q8TEY7,P42892,O75312,Q12899,Q9UIQ6,Q8NB78,Q6GQQ9,Q969R5,Q8NCC3,Q9Y3Z3,Q9NWV4,P55786,P29372,O75976,P09960 15 +Beta tubulin binding 0.368256121674209 0.404754952455643 0.6856576444034745 1.0 0.9079490966350124 17 Q66K74,O75347,P60520,Q9H0H5,Q9HC35,Q9H6U6 6 +Hydrolase activity acting on carbon nitrogen but not peptide bonds 0.3630538620381513 0.4032624119653764 0.6867551903799651 1.0 0.9079490966350124 22 Q13510 1 +Translation regulator activity nucleic acid binding 0.335185052654204 0.4015613526584932 0.6880068771572592 1.0 0.9079490966350124 64 O75821,O60841,P04818,Q13347,Q92905,O00178,O43583,Q9NR50,P55010,A9UHW6,O00303,P24534,P23588,P15170,Q9Y262,P62495,Q04637,P63241,P06730,P26641,P55884,P05198,P49770,O15372,Q7Z2Z2,P20042,O75822,Q15056,P29692,Q6PKG0,Q13144 31 +Histone threonine kinase activity 0.4765265229584978 0.4015102221790224 0.6880445136427804 1.0 0.9079490966350124 4 Q9Y4B6 1 +Nuclease activity 0.3324580253584188 0.4014785583902381 0.6880678213361338 1.0 0.9079490966350124 69 Q99598,Q9HBH5,O00584,Q8IV08,Q9Y3Z3,O00115,Q9UQ84,P18887,P23396 9 +Cis trans isomerase activity 0.3536910844963947 0.396239155332915 0.6919286083919127 1.0 0.9079490966350124 29 O00170,O95302,P62942,Q13526 4 +Phosphoric ester hydrolase activity 0.3323773389334155 0.3950002515162302 0.6928427023522037 1.0 0.9079490966350124 68 P34913,P10586,Q9H0R4,Q8IV08,Q9H0C8,Q9Y3Z3,Q10713,P11117,Q9NX62 9 +Transition metal ion binding 0.3839270913263213 0.3949496128255493 0.6928800743600474 1.0 0.9079490966350124 187 P42892,Q9UIQ6,Q06481,Q6GQQ9,P05067,Q10472,O75976,Q8TEY7,Q12899,Q8NB78,Q8NCC3,Q969R5,P02792,Q9Y3Z3,Q32P28,Q9NWV4,P29372,P09960,Q6PK18,O75312,P55786,Q16850,Q9BU89 23 +Tau protein kinase activity 0.4173111243307537 0.386893134897965 0.6988353237156804 1.0 0.9129631387817664 6 Q00535,P49841,P49840,Q7KZI7,O75116 5 +Kinase activator activity 0.3609238549587041 0.36399501395176 0.7158617326616334 1.0 0.926307106156613 16 Q8N122,Q9Y376,Q13177 3 +Leucine zipper domain binding 0.5730837789661423 0.3581358780961459 0.7202416305155186 1.0 0.926307106156613 2 Q9NY61 1 +Phosphatase binding 0.3320590245148355 0.3566878652101762 0.7213254909467226 1.0 0.9268538500109944 47 P19022,Q12959,P78318,P17931,P62993,Q86XL3,O00459,O60493,P53634,P35269,P56962 11 +Notch binding 0.4560639364158612 0.3488448473436635 0.727205792495853 1.0 0.9335570712058988 4 P78536 1 +Dna polymerase binding 0.3730363828706451 0.3428589286639998 0.7317045911392497 1.0 0.9365622892716698 10 P07900,P08238,P09429,Q9BXW9 4 +Ubiquitin binding 0.3438550870284895 0.3414361281399111 0.7327752810710184 1.0 0.9365622892716698 33 Q8TEY7,P04792,Q9UNZ2,P61088,Q99816,P49459,Q9Y6K9,P45974,P46934,O14964,Q9H1I8,P54727,Q96FW1,Q04323 14 +Protein phosphatase 2a binding 0.3695732171080436 0.330615967694699 0.7409345834247785 1.0 0.9417967247555344 10 P78318 1 +Microtubule plus end binding 0.3771341471309794 0.330546334105774 0.7409871885603245 1.0 0.9417967247555344 9 Q15691,Q15555,P43034,Q14203,Q03001 5 +Phosphatidylinositol phosphate phosphatase activity 0.3900088740966121 0.3232601629537842 0.7464982210682725 1.0 0.9462369342730264 7 Q10713 1 +Ubiquitination like modification dependent protein binding 0.4067796610169556 0.3120072317044763 0.7550350273901578 1.0 0.9481760907760396 5 Q16658,Q99543,P14735,Q12888 4 +Small ribosomal subunit rrna binding 0.3905660765237393 0.3101014045343331 0.7564838442152362 1.0 0.9481760907760396 6 P23396 1 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.342545829275373 0.3032099678232241 0.7617298531477568 1.0 0.9481760907760396 25 Q8IV08,Q9HBH5 2 +Dynein intermediate chain binding 0.3686587323095275 0.3026194003572925 0.7621799279798869 1.0 0.9481760907760396 9 Q96FJ2,P42858,P62826,P43034 4 +Clathrin light chain binding 0.5407011289364347 0.2864953905396598 0.7744987234021263 1.0 0.9573663230382938 2 O00291 1 +Protein phosphatase regulator activity 0.3415435082797451 0.2834524417401539 0.776830033239398 1.0 0.9587718041823096 18 P19525,P78318,P17931,Q86XL3,Q01105,Q6IN85 6 +Protein disulfide reductase nad p activity 0.3945881653285851 0.2825412172398607 0.7775285466044819 1.0 0.958792870352766 5 P00558,Q6DKJ4,P00390,Q16881 4 +Polyubiquitin modification dependent protein binding 0.3421303539331015 0.2798423416584047 0.77959846502143 1.0 0.9596632023492144 16 Q6GQQ9,P42566,Q9Y6K9 3 +K63 linked polyubiquitin modification dependent protein binding 0.422121802950534 0.2720811974600347 0.7855595866204368 1.0 0.9614635311374736 4 Q6GQQ9 1 +Alpha tubulin binding 0.3756438854219994 0.2712174749641392 0.786223773443236 1.0 0.9614635311374736 6 Q9HC35 1 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.5311942959001867 0.2678938064691534 0.788781061233816 1.0 0.9625454927632082 2 O95881 1 +G protein activity 0.3403874813711059 0.2648847251540851 0.7910982657231118 1.0 0.963305810069343 13 P61020,P60953,P61225,P63000,Q9H0U4,P20339,P51149,Q15286,P51148,P20338,P11233,P62820 12 +Molecular function inhibitor activity 0.3409337823667424 0.2576259033992817 0.7966956363417372 1.0 0.9659781931358716 11 Q96PU5,Q9UKS6,P62942 3 +Low density lipoprotein particle receptor binding 0.3463371054198864 0.2529798261673622 0.8002838026260897 1.0 0.9676997145613174 10 P30533,O95782,Q96CW1,Q00610,O00213,Q15036,P31689,Q13492,P14625 9 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.3301877495479668 0.2512331078143863 0.801633888895378 1.0 0.9676997145613174 32 Q6PK18,Q8NB78,Q16850,Q32P28,O15121,Q9BU89 6 +Anaphase promoting complex binding 0.5089752788688341 0.2489653031809743 0.8033876205327022 1.0 0.9676997145613174 3 Q12834 1 +Cell adhesion molecule binding 0.3982256100286817 0.2481618072419897 0.8040092155807961 1.0 0.9676997145613174 251 Q9UQN3,Q15691,Q07960,P43487,P47756,A0MZ66,Q8NC51,Q9NTK5,Q14847,O00299,Q02487,Q14247,Q12959,Q08431,Q6IBS0,P06756,P07942,Q9P273,Q9Y624,O60749,P29692,P46060,P29317,Q16181,P08195,Q14126,Q9H444,Q6PCB8,Q13596,P15311,P07737,P78310,Q9Y2I1,P05556,Q96TA1,Q9H2G2,Q9Y5K6,P55010,P20810,P22061,P19022,Q05682,P63104,Q9NSV4,P10586,Q08379,P11047,P28072,Q9Y6W5,Q9UHX1,Q03001,P09429,Q8N3F8,Q92692,Q15056,P35613,Q08722,Q9UQB8,Q8WU90,Q9NYL9,Q9UBC2,Q9UGI8,O00560,Q15417,O43707,O60645,O60763,Q9BXI6,P08865,Q9H4M9,P35579,P78536,O75874,Q9NUQ8,P49768,Q13308,P42566,P05198,O60664,Q9UNF0,Q9UJU6,Q9H223,P08238,P26641,Q13177,Q6PKG0 86 +Mhc class ii protein complex binding 0.364971978004475 0.2452959930083044 0.8062272541122384 1.0 0.9690792429405816 6 P08238,P62258,P07900 3 +Kinetochore binding 0.5172311348782064 0.2426208274127492 0.8082991452788899 1.0 0.9702833453542172 2 Q7Z460 1 +C3hc4 type ring finger domain binding 0.5034175334323938 0.2396510860876528 0.8106007575838965 1.0 0.9707260688071646 3 P0DMV9,P31689 2 +Phosphodiesterase i activity 0.5154486036839103 0.2395705392402606 0.8106632060045618 1.0 0.9707260688071646 2 P27695 1 +Muscle alpha actinin binding 0.4033888228299567 0.2358188774796292 0.8135732191102212 1.0 0.97201451297547 4 Q96HC4,Q8WX93,Q9NR12 3 +Acyltransferase activity 0.3178049625629585 0.235488688426894 0.8138294573581999 1.0 0.97201451297547 58 Q86UY6,Q9UJ14,Q8NCC3 3 +Uridylyltransferase activity 0.5127748068924667 0.2350698451198012 0.8141545230709568 1.0 0.97201451297547 2 Q16851 1 +Damaged dna binding 0.3271656441027295 0.231937909430465 0.8165862397861496 1.0 0.97201451297547 31 P09429,P26583,P29372,P13051,P23396 5 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.3712025826967776 0.2316287374399381 0.8168263851961255 1.0 0.97201451297547 5 Q68D91 1 +Co smad binding 0.5062388591800489 0.2244451639298786 0.8224109312303076 1.0 0.9756850817316276 2 Q9UPN9 1 +Histone kinase activity 0.3418177780371343 0.2211302168766935 0.8249910429142193 1.0 0.9757243461847136 9 Q9Y4B6,P06493 2 +Ubiquitin conjugating enzyme binding 0.3654475170978352 0.2202710812448604 0.8256600408900125 1.0 0.9757243461847136 5 Q9Y4X5,O75150,Q9BTE7,Q9UBS8 4 +Poly g binding 0.3537989292992045 0.2199206221085955 0.8259329753418578 1.0 0.9757243461847136 6 Q86TB9 1 +Protein phosphatase activator activity 0.3881609491250098 0.2096724447510264 0.8339233333741807 1.0 0.9826885511369114 4 Q6IN85 1 +Copper chaperone activity 0.4808320950965841 0.2052551829084585 0.8373727573853083 1.0 0.9842802586809763 3 O43819,Q99497 2 +Metallochaperone activity 0.4808320950965841 0.2052551829084585 0.8373727573853083 1.0 0.9842802586809763 3 O43819,Q99497 2 +Hydrolase activity acting on ester bonds 0.3600924572105164 0.2025908499014228 0.8394548424219241 1.0 0.9859039760330944 176 P34913,Q8NHP8,P15586,O00584,Q8IV08,Q8NCC3,Q9UMR5,O00115,P50897,P38571,P11117 11 +Profilin binding 0.3781212841854771 0.1940805717309693 0.8461127938962685 1.0 0.9912412164962944 4 P42858,Q14247,Q8N8S7 3 +Protein tyrosine phosphatase activity 0.3190132298942701 0.1924745162806069 0.8473705277606036 1.0 0.9916060293899652 14 P10586,Q9ULE6,P24666,P51452,Q8NCE2,Q99956 6 +Intermediate filament binding 0.3766349583828637 0.1918831626569765 0.847833726621271 1.0 0.9916060293899652 4 P48681,Q99959,P08670 3 +Glutamate receptor binding 0.3382921749479337 0.1907696722143805 0.8487060503486707 1.0 0.9918018379074582 7 O00291,O75955,Q15334,O14745,P23634,P27824 6 +Adenylate cyclase binding 0.4774212715389327 0.1838960139513054 0.8540950318891256 1.0 0.9933476549922544 2 Q02952 1 +Organophosphate ester transmembrane transporter activity 0.3175116870333632 0.1836052657511106 0.8543231318815989 1.0 0.9933476549922544 13 O00400 1 +Nucleotide transmembrane transporter activity 0.3175116870333632 0.1836052657511106 0.8543231318815989 1.0 0.9933476549922544 13 O00400 1 +Smad binding 0.3172638250943325 0.1827797128645279 0.8549708672321392 1.0 0.9933476549922544 13 O95373,Q9UNE7,P62942,Q9H6Z4 4 +Large ribosomal subunit rrna binding 0.365933412604033 0.1768999321914605 0.8595869918846524 1.0 0.9950124499139764 4 P62829,P30050,P05388 3 +Mhc protein complex binding 0.3293656473070552 0.1719984958578414 0.863438711508606 1.0 0.9970074319830944 7 P08238,P62258,P07900 3 +Histone deacetylase activity h3 k14 specific 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.9970074319830944 2 Q92769 1 +Nad dependent protein deacetylase activity 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.9970074319830944 2 Q92769 1 +1 alkyl 2 acetylglycerophosphocholine esterase activity 0.4652406417112443 0.1697498402872916 0.8652068759426852 1.0 0.9970074319830944 2 Q15102 1 +Deoxynucleoside kinase activity 0.4469539375928694 0.1639062432586379 0.8698049521635953 1.0 1.0 3 P27707,P55263 2 +Calcium dependent protein kinase activity 0.4404160475482932 0.1572897356557045 0.8750165093305384 1.0 1.0 3 Q16512,Q16513 2 +Protein kinase c activity 0.4404160475482932 0.1572897356557045 0.8750165093305384 1.0 1.0 3 Q16512,Q16513 2 +Dihydropyrimidinase activity 0.4530600118835558 0.1572890343334612 0.8750170620254456 1.0 1.0 2 Q14195 1 +Lipase binding 0.4524658348187902 0.156722863657645 0.8754632671560814 1.0 1.0 2 P30533 1 +Syntaxin binding 0.3113968394867531 0.1556531152459029 0.8763064552245661 1.0 1.0 16 Q15833,O15400,P49755,Q9UNK0,Q08379,P54920 6 +Sh3 domain binding 0.3137957737875234 0.1545713264636011 0.8771592764388567 1.0 1.0 27 Q16204,P78536,Q07960,Q96JJ3,Q9Y5K6,P62993,P46108,Q9Y6W5,P42566 9 +Atpase coupled transmembrane transporter activity 0.314579752070437 0.1525769982639592 0.8787318653125786 1.0 1.0 24 P08183,P33527,P51798 3 +Ubiquitin protein transferase regulator activity 0.3069312090842289 0.1494923734210626 0.881165126876817 1.0 1.0 13 P62829,P62913,P60866,Q12834,P46777 5 +Pre mirna binding 0.3214391911983412 0.1491142991481636 0.8814634429473771 1.0 1.0 5 O75569,P62826,Q9HAV4,Q9UPY3 4 +Ionotropic glutamate receptor binding 0.3379904875148558 0.1445341369884154 0.8850787020240494 1.0 1.0 4 O75955,Q15334,P27824 3 +Mismatched dna binding 0.314954725918104 0.1409518117446106 0.8879080108315434 1.0 1.0 5 P43246,P52701 2 +Dna insertion or deletion binding 0.314954725918104 0.1409518117446106 0.8879080108315434 1.0 1.0 5 P43246,P52701 2 +Transketolase or transaldolase activity 0.4202080237741477 0.1394532186781509 0.8890920207283823 1.0 1.0 3 P37837,P29401 2 +Protein tyrosine kinase binding 0.3094554233614794 0.1385120535241283 0.8898357441033333 1.0 1.0 20 P05556,O75312,Q96JJ3,P46108,O00459 5 +Snare binding 0.3102013009018778 0.1335828292047615 0.8937324627929757 1.0 1.0 30 Q15833,O15400,Q9UNK0,P49755,Q9UEU0,P60520,Q08379,O95487,O60645,Q86Y82,P54920,Q12846,P56962 13 +Oxygen sensor activity 0.4212715389186139 0.1320465421853976 0.8949474786882232 1.0 1.0 2 Q99497 1 +Signaling receptor complex adaptor activity 0.3035360332486779 0.1291975151971457 0.8972013623182642 1.0 1.0 6 O60271,P46108,Q06124 3 +Calmodulin dependent protein kinase activity 0.4159239453357229 0.1287370649030933 0.8975657058782116 1.0 1.0 2 P46020 1 +N6 methyladenosine containing rna binding 0.3012346011758575 0.1259712214424181 0.8997547050329784 1.0 1.0 6 Q7Z739 1 +Amidine lyase activity 0.3163259831927497 0.1257337843434481 0.8999426580384631 1.0 1.0 4 Q8WUX2 1 +Phosphatidylinositol 3 kinase binding 0.400000000000002 0.1252922240927332 0.9002922079504572 1.0 1.0 3 O14654,P50570 2 +Complement binding 0.3958395245170895 0.1227960867683552 0.9022685731152776 1.0 1.0 3 P27797,Q07021 2 +Gamma tubulin binding 0.3017464007687583 0.1220662570700169 0.9028465449545732 1.0 1.0 7 Q9H0H5,Q96CW5 2 +Pentosyltransferase activity 0.3000298240381636 0.1208388837575285 0.9038186509707722 1.0 1.0 15 Q9NRG1,Q7Z4H8,P09874,P43490,P07741,Q9UGN5,P00491,P00492,Q9ULX3,Q06203,Q8NBL1,P11172,Q9H974,Q13126 14 +Phosphatidylinositol 3 kinase regulatory subunit binding 0.3998811645870586 0.1202258137158066 0.9043042696951882 1.0 1.0 2 P50570 1 +Syntaxin 1 binding 0.3076694411414932 0.1196179800889338 0.9047857759425824 1.0 1.0 4 Q15833,O75150,P46459 3 +Protein tyrosine serine threonine phosphatase activity 0.2949747249479705 0.1193577009113164 0.9049919714507686 1.0 1.0 5 Q8WUK0,Q99956,P51452,Q13614 4 +Death domain binding 0.306183115338876 0.1186427708851282 0.905558378376944 1.0 1.0 4 P63244,Q07812,Q07820 3 +Nadplus adp ribosyltransferase activity 0.299048751486317 0.114254357207391 0.9090361631600812 1.0 1.0 4 P09874,Q9ULX3,Q9UGN5 3 +Keratin filament binding 0.3764111705288245 0.1111144759904266 0.9115255696463244 1.0 1.0 2 P08670 1 +Wd40 repeat domain binding 0.2925089179548072 0.1106400038095048 0.9119018237583832 1.0 1.0 4 P40227,Q96K76,Q99459 3 +Cullin family protein binding 0.2925089179548064 0.1106400038095045 0.9119018237583834 1.0 1.0 4 P63208,Q9BTE7,O60826 3 +Acetyltransferase activity 0.3068236349288947 0.1101333424982261 0.9123036254985326 1.0 1.0 33 Q86UY6 1 +Phosphatidylinositol phosphate 4 phosphatase activity 0.3672014260249626 0.108450055604709 0.9136386966123268 1.0 1.0 2 Q01968 1 +K48 linked polyubiquitin modification dependent protein binding 0.2809991079393497 0.1072636276611674 0.9145798389440944 1.0 1.0 5 Q92890,Q9NRR5,P55072,Q04323 4 +Ligase activity forming phosphoric ester bonds 0.3545319465081744 0.1046325166022993 0.9166674117996 1.0 1.0 3 P18858,Q9Y3I0 2 +5s rrna binding 0.2839602806065174 0.1042683106839518 0.9169564252172424 1.0 1.0 6 Q9NZM5,P62913 2 +Fucosyltransferase activity 0.3475935828877096 0.1041509243527397 0.917049578775544 1.0 1.0 2 Q9Y2G5 1 +Sequence specific mrna binding 0.289325642206816 0.1036278780349242 0.9174646632922344 1.0 1.0 7 P62495,Q06787,P04818 3 +1 phosphatidylinositol 4 kinase activity 0.3098633392751134 0.0996804612654076 0.9205980129241802 1.0 1.0 2 Q9BTU6 1 +Passive transmembrane transporter activity 0.3028311703060113 0.0984031401236056 0.921612181325645 1.0 1.0 39 P51790,Q9C0H2 2 +Acidic amino acid transmembrane transporter activity 0.2607790663098492 0.0937007113430762 0.9253469051951266 1.0 1.0 5 Q9UPY5,O75746,Q15758,Q9H936 4 +Histone arginine n methyltransferase activity 0.2632986627043113 0.0915247883000204 0.9270756106789776 1.0 1.0 3 O14744,Q99873 2 +Vitamin d receptor binding 0.2537180249851191 0.0762845031366094 0.9391927546215386 1.0 1.0 6 Q9NPJ6,Q9Y2W1,Q15648,O60244,O75448 5 +Mrna methyltransferase activity 0.2495538370017762 0.0733386137462106 0.941536665089663 1.0 1.0 6 Q8N1G2,Q7L0Y3,O43148,Q9HCE5,Q08J23 5 +O methyltransferase activity 0.2621339226692107 0.0716070395046526 0.942914637745108 1.0 1.0 7 Q9H993,O60725 2 +Udp glucosyltransferase activity 0.2588515322820641 0.0684754770063234 0.9454071407602924 1.0 1.0 7 Q7Z4H8,P46976,Q9NYU1,Q8NBL1,P13807,Q9Y673 6 +Protein heterodimerization activity 0.2958783498137688 0.0646300409564791 0.948468565480932 1.0 1.0 67 P05556,O00560,Q86X10,Q9P273,Q06787,P43034,Q9Y6K9,Q92530,O00459,Q9NRF9,Q13564,P06865 12 +G protein beta gamma subunit complex binding 0.2466350223103365 0.0581041545175274 0.9536656651598204 1.0 1.0 7 P41208 1 +Ubiquitin like protein binding 0.2953795986895101 0.0453034011875784 0.9638654764680834 1.0 1.0 37 Q8TEY7,P04792,Q9UNZ2,P61088,Q99816,Q9H1I8,P49459,Q9Y6K9,P45974,Q8NC51,P46934,O14964,P54727,Q9UBT2,Q96FW1,Q04323 16 +Receptor tyrosine kinase binding 0.2706333066294076 0.0237386339807003 0.981061089220112 1.0 1.0 16 O75312,Q96JJ3,O00459 3 +Nucleobase containing compound transmembrane transporter activity 0.2625434429787021 0.0137491674831945 0.9890300971667076 1.0 1.0 15 O00400 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b0ecee09a0db53c39a7f41130ae2e52ac727517c --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co receptor binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Ige binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide hormone activity", "Neuropeptide receptor activity", "Neuropeptide receptor binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur amino acid transmembrane transporter activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf131", "C1orf35", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GID4", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLPH3", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGI3", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFB", "NELFCD", "NEMF", "NENF", "NEO1", "NES", "NET1", "NF2", "NFS1", "NFU1", "NFYB", "NGDN", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TATDN1", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM106B", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMEM38B", "TMEM43", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", 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0.0711332726649859 1.094486762177302e-05 0.0003832983840783 0.0049531384619904 +Abnormal aortic valve physiology 7 40 2.5782371597774043 0.009930581599419 8.133495145631068 38.407766990291265 0.3164235083362472 0.5832127363016096 3.634936253961654 4.470913316924635 0.8570668738614753 0.3290269262839486 0.0657676989389297 0.4308176920885813 0.025600369736322 0.0067262795093058 0.1039863786928125 +Limb ataxia 7 26 2.5675787265342502 0.0102411531519748 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0013222283947593 0.0029741493546945 0.0026232179628348 8.541553079506396e-05 0.0020586259473287 +Abnormal autonomic nervous system physiology 4 29 2.554912108179649 0.0106214614019031 8.24757281553398 32.320388349514566 0.4638475540870246 0.4509985093876737 3.0051523606495087 3.6502788621576223 1.089960321271389 0.3249871136051702 0.0238915801945627 0.0060673937801388 0.006515948460693 0.0379484136991646 0.0763793310526922 +Macroglossia 8 35 2.5520879015121203 0.0107079499595026 8.597087378640778 33.800970873786405 0.2378332400826553 0.526108686434358 3.4819634097071916 3.0993577519995683 1.045257905641647 0.335668429128709 0.0094862494346252 0.3958501174260305 0.0032262047126005 0.0008482797638478 0.0604882113043601 +Chronic diarrhea 3 18 2.548084452986917 0.0108316245649147 4.514563106796117 18.550970873786408 0.2309588263877121 0.4319883908654413 2.0282666456418785 2.0703229027090826 1.177819281609388 0.3206617066576645 0.0065179254011117 0.2067156970649581 0.0011244794942918 0.0272622697998741 0.0256439269364036 +Abnormality of glycolipid metabolism 4 7 2.547947372956948 0.0108358816344493 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 8.260784500368952e-07 1.2998708524751297e-05 1.9890785041035153e-08 1.902860843189295e-06 5.542830198350017e-05 +Abnormal cerebral artery morphology 2 16 2.5285045212595003 0.0114549611055425 3.6893203883495143 15.189320388349516 0.1461288400266414 0.5737075812512653 2.321403685727363 2.2061437876789474 0.9153426901574684 0.3191805767887729 0.0073202198372533 0.0239365913087713 0.0121710399777804 0.0311941867040692 0.0888810791636133 +Progressive neurologic deterioration 5 19 2.527856917131443 0.01147611109619 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.0050775930259089 0.0187248462666395 0.0008016777344491 0.00057064251751 0.0171255123594616 +Foam cells 4 6 2.514918621745887 0.0119059861954755 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 2.7880368387547653e-07 0.0385773062479974 4.489622950296432e-09 4.402192379002321e-07 1.3367261604228735e-05 +Clumsiness 4 21 2.514738783320672 0.0119120606109297 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 4.557198944336205e-05 0.0017444833819082 0.0001111606586644 0.0066284009542843 0.03080273588529 +Abnormal oral mucosa morphology 10 61 2.514231002651602 0.0119292267908863 12.099514563106796 58.75485436893204 0.3909737086326091 0.6033731457854445 5.163567269709676 5.859238885605998 0.9283175157401292 0.3479637416005023 0.0701126248187899 0.6124177022714303 0.0111235313714806 0.0071714841181843 0.0832994475888181 +Abnormal retinal vascular morphology 7 51 2.4902986923679755 0.0127635778408408 11.550970873786408 50.40291262135922 0.374132464893944 0.4137648703700375 4.646725961814426 4.349733979382428 1.4638612584769457 0.3720428539009304 0.0016135851703204 0.040162898931708 0.0001357276449293 0.0046732560283147 0.1355124819775376 +Abnormal mitral valve physiology 9 42 2.482772112011274 0.0130364457447016 9.37621359223301 38.37864077669903 0.2302649184785056 0.5746059188976989 3.903784227411165 4.570093803830835 0.8587145467195402 0.3157753352621624 0.0644013389683458 0.1058856107488554 0.0248840898146938 0.0004308768069952 0.021690291144078 +Macular degeneration 3 13 2.472194242787748 0.0134286530115981 3.5072815533980584 13.201456310679612 0.7081764422831481 0.3007939344006393 1.5711122114355351 1.3240485924903622 1.388921785741595 0.3097317018961461 0.0668350320040178 0.2260688267312995 0.0142951840993497 0.0376866621833409 0.2469963169810251 +Arthralgia 7 36 2.471469791582156 0.0134558919200489 8.067961165048544 33.66019417475728 0.4973169065736986 0.5336317295986659 3.339269543758109 3.852381429809718 0.8994568503620952 0.3283969638661596 0.0085583503221168 0.0846927074460255 0.0028349238604318 0.002856471114128 0.0221657817876628 +Abnormal macrophage morphology 4 6 2.461805932394218 0.0138239444269145 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 6.897469018601627e-06 0.0756950383436983 3.290290363905812e-07 2.923978855186412e-05 0.0007525839576665 +Hypotension 5 26 2.4497486227592984 0.014295597861043 5.793689320388349 25.03640776699029 0.6365055246627263 0.462216755489837 2.8014661523044153 2.878803471228818 0.9034755319984747 0.3145597767048137 0.0856229888655945 0.2560754722464486 0.0209290225413289 0.0033194180753683 0.0082674211913202 +Abnormal systemic arterial morphology 25 145 2.4478413414025355 0.0143714924284539 26.512135922330096 139.09223300970874 -0.0457047476890588 0.6345296488429398 8.296820557307836 14.036057514403687 1.004196439476248 0.3481529181225943 6.220199940421012e-05 0.0110171777183305 4.799875219039508e-06 8.048027433741673e-06 0.0022559462511385 +Retinal degeneration 7 54 2.446651910735191 0.0144190019886398 11.890776699029129 56.16747572815534 0.249024006789609 0.518990175786131 4.729602333356375 6.268553853518324 1.1275766261124216 0.3578686327011649 0.0192077657324274 0.0660022239528654 0.0108581919062207 0.0433911008848294 0.4481084986123512 +Abnormal tongue morphology 14 75 2.442658999807828 0.0145795057865505 16.939320388349515 69.1116504854369 0.4277424777250148 0.5766387697572775 5.679438944349523 6.766002978496539 0.9505300446189564 0.3567930620053219 0.0979567535704115 0.6563757710533937 0.00513337455605 0.0007968358827935 0.0336265347831016 +Cerebral inclusion bodies 3 14 2.4419323491939684 0.0146088839145415 3.844660194174758 13.655339805825244 0.5051551663301821 0.4226246963159299 1.8115448621120656 1.6612796655742368 1.090041660052819 0.3107400387490911 0.0023797484711094 0.0112943240362007 0.0040346592713098 0.0081443152876 0.0206839034685982 +Hypersplenism 3 8 2.438612515118055 0.0147437680608788 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 0.0072960555134274 0.0027067874988798 0.0004672463302539 0.0005013179159177 0.0007525839576665 +Hallucinations 7 48 2.4377331313163317 0.0147796806133586 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 0.0013015424048419 0.0014196759684226 0.0029612996216462 0.0030409582401221 0.0092647359154464 +Abnormal form of the vertebral bodies 17 88 2.4363722327937496 0.0148354093861038 19.968446601941743 83.88349514563107 0.6644002102675167 0.5345165392282933 7.187939907318809 8.37593753149639 0.9881357365384656 0.3722270618536288 0.0499487852126237 0.1193188519497329 0.0940079969548859 0.0010261989167063 0.0043667772194004 +Urinary glycosaminoglycan excretion 3 6 2.4349153633419105 0.0148952733026992 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 5.205315512859705e-06 4.844157765872774e-05 1.094486762177302e-05 0.0003832983840783 0.0049531384619904 +Psychomotor deterioration 2 9 2.432725462303144 0.0149856584870677 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 0.0001402743658599 3.066034551708988e-05 0.0002437892001771 0.0034327477034809 0.0228394808772788 +Abnormal rib cage morphology 13 78 2.42746979542396 0.0152045528449047 17.694174757281555 75.7135922330097 0.5488633555797945 0.5379800174608891 5.594611229067785 9.71314341791714 0.9782995531616954 0.3690468558866111 0.0551015861213607 0.1268711753712451 0.1028108057738298 0.0214029501811285 0.172667232828472 +Increased cerebral lipofuscin 3 5 2.425790845983656 0.0152750706624122 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 8.260784500368952e-07 1.0515666421094113e-07 1.7486004913858212e-06 6.494328716879693e-05 0.0009257875785001 +Periventricular white matter hyperintensities 2 8 2.415425606270306 0.0157168327439225 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0002205530010257 0.0023758658868836 0.0003823532959252 0.0052676758380378 0.0338099842169397 +Mucosal telangiectasiae 3 10 2.4037545784110868 0.0162276635931302 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0014713217280779 0.0003334624710947 0.002509898486982 0.0044816860022438 0.0451666412494461 +Parkinsonism 9 35 2.3980510375886284 0.0164825684629998 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0328380085431387 0.0663917661810799 0.0015255239830935 0.0049682424819734 0.008797449771973 +Follicular hyperkeratosis 2 8 2.394469790359883 0.0166444145174582 1.6237864077669903 6.281553398058253 0.163232926315914 0.5516766232178576 1.549104731430856 1.0986971607463736 0.8802887205766023 0.2969102369878216 0.0001402743658599 0.0017760204843955 0.0002437892001771 0.0034327477034809 0.0228394808772788 +Oligosacchariduria 3 5 2.390558032048024 0.0168227903065765 2.4611650485436893 4.978155339805825 0.0914492290535993 0.2254706360721404 1.281286747781515 0.9537908500181173 1.6653598868357138 0.2594196870884814 2.7880368387547653e-07 0.0385773062479974 5.917417658315479e-07 2.2502069418558096e-05 0.0003337445501144 +Hyperkeratosis 8 62 2.3785238237627757 0.0173821136674316 13.094660194174756 57.89563106796116 0.1723425509703818 0.5977105968768013 4.958396882240626 5.528503400059701 0.8720789465254253 0.3306400628576269 0.0019570479599773 0.0078469619445788 0.0049660902785127 0.0060885090037902 0.0507669399819131 +Sepsis 2 22 2.3524602667402315 0.0186496821212309 3.8567961165048543 18.944174757281555 0.35575678916449 0.5917235453265804 2.566849420734061 2.7162384842720413 0.8248844983225841 0.3143879015041122 0.0856229888655945 0.0348230103466341 0.0209290225413289 0.1804107268936248 0.5656452495630921 +Cupped ear 3 13 2.350492270082988 0.0187485970758705 2.3179611650485437 12.764563106796116 0.7982932305779684 0.4421342276468993 1.7676619735856678 1.9903667402216707 0.7602182664838703 0.2945303748359003 0.3083107652154563 0.1988423464133734 0.0718258186813318 0.3010844649684869 0.174947649934789 +Increased circulating antibody level 5 14 2.341818635235888 0.019190037596237 3.2402912621359223 15.145631067961164 0.5908116743587006 0.4340890712285613 1.9578142936372311 2.533878285328643 0.9673694377645128 0.2975830104493745 0.3575967580900071 0.2336798458054532 0.4135270958140081 0.1448032950165304 0.0465202107555725 +Pulmonary infiltrates 2 6 2.323911446692542 0.0201302406394749 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.191665926491972 1.0 0.0265618978442646 0.0247234076565489 0.1309583783231107 +Abnormal morphology of the conjunctival vasculature 2 7 2.3169743200529163 0.0205051306921921 2.6359223300970873 7.330097087378641 0.3791669082255805 0.3264494094231241 1.4642904354684148 1.4524057679745994 1.3542312898692437 0.2989163062985944 0.0004587899988766 0.0001017478453213 0.0007914120786236 0.0104402688493973 0.0624183143373935 +Progressive psychomotor deterioration 3 8 2.311364997130854 0.0208127026450597 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0040983965897468 0.0573151884822011 0.000188873280149 0.0001472775053537 0.0020183200628615 +Increased bone mineral density 7 24 2.30910028437794 0.0209380169921165 6.242718446601942 24.75 1.1480702818250033 0.3148175930983396 2.4533156459354677 2.2345749579547443 1.0849696139569316 0.312718333498069 0.1270753973132237 0.0533785743764077 0.0384628064123942 0.0024819922622898 0.0311266180128976 +Abnormal arterial physiology 7 29 2.307660010007206 0.0210180539482092 6.218446601941747 26.953883495145632 0.6799967252485163 0.4871419269266132 2.869465887610158 2.4604264895945303 0.8630108658008876 0.3264277839815205 0.1692915635889003 0.0732573258319426 0.0599224496562618 0.0237395007847449 0.0753921627758266 +Abnormal pulmonary interstitial morphology 3 30 2.299411770590181 0.0214815681885414 6.371359223300971 30.5995145631068 0.4103689768813533 0.4555813960836699 3.330566746297264 2.186076806332745 1.1224431747517174 0.329794447909787 0.0281740632520034 0.0597604037758126 0.0450913351422118 0.1359283502231961 0.5617932813103594 +Abnormal exteroceptive sensation 8 56 2.297883020284324 0.021568447942768 10.759708737864075 52.02427184466019 0.4941713240335635 0.5557419524937993 3.9194595318694754 5.696566262954939 0.9102536370390476 0.3437672640084617 0.0265537390997117 0.0046881619119119 0.0024059724979233 0.0069786833473203 0.038657228672346 +Tissue ischemia 5 23 2.2827309184454374 0.0224462233750191 4.669902912621359 20.01941747572815 0.4670703905456849 0.5376214087969519 2.554791232762714 1.8952192409705757 0.8387891641382008 0.309595447618788 0.1189734911484879 0.0496758524768897 0.0347449548593629 0.0326937613140359 0.1445179295897953 +Acute coronary syndrome 4 19 2.277999819144953 0.0227265883738789 4.315533980582524 18.70145631067961 0.2769714958633372 0.5546791842077856 2.372465731449787 1.7054162193144966 0.8386723383602402 0.2931039621058641 0.0559096038955752 0.0221396463904123 0.0108633849740392 0.0055460197819823 0.0772454186514108 +Ovoid vertebral bodies 2 8 2.2773538996322107 0.0227651006744262 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0006223592227998 0.0046633751497463 0.0010709052035729 0.0138257504316944 0.0798154053066686 +Osteolysis 6 29 2.270080985821925 0.0232026697682932 5.286407766990291 27.73543689320388 0.5057473150905948 0.5186942536500823 2.7835351045722914 3.2828484188526224 0.8911453392732208 0.3083503296551068 0.0133377930203514 0.2597451867723493 0.0218582842409203 0.0163483070474244 0.0026068114295301 +Dermal atrophy 5 31 2.265455489267165 0.0234847425018966 5.320388349514563 26.895631067961165 0.7910895542770026 0.4477466139002859 2.6272049167180267 2.645986214694848 0.8422228280317593 0.3177571120785681 0.1189734911484879 0.3024216363859021 0.0347449548593629 0.0086869143045309 0.1445179295897953 +Abnormal coronary artery morphology 2 7 2.262085993364072 0.0236920908131974 1.9757281553398056 6.191747572815534 -0.2703065107883424 0.4168780216498282 1.563973407479924 1.1080595539570373 1.1225154197172134 0.2930835784447153 0.0035736152074797 0.1706778675257841 0.0060217503205503 0.0649283885443843 0.2822516950414785 +Abnormal vertebral morphology 20 112 2.2595580190720024 0.0238486955852772 25.18446601941747 107.1383495145631 0.7050611944944222 0.5078087978506296 8.434496402822974 10.278065304429203 1.0858158093436174 0.3796440707216367 0.0149784340174164 0.0194799622426816 0.0370549257844476 0.0008224707990169 0.0036537640417625 +Paresthesia 5 26 2.2591438959361207 0.0238744353911777 5.66747572815534 23.635922330097088 0.7476018604198311 0.4719429115693522 2.535880467324221 3.039141242047335 0.8424234714329004 0.3217041155902614 0.0230810279302175 0.0058478787222266 0.0062190088773383 0.0098712464387859 0.0722113180084966 +Glomerulopathy 2 10 2.255421583716382 0.0241068792309577 2.820388349514563 9.96359223300971 0.665958332940798 0.3017859836474246 1.512655943869742 0.8764085521210618 1.2285906000166364 0.2785070215881056 0.0148267428903527 0.0055832614279084 0.0014058650888959 0.017764157863851 0.09905667817091 +Retinal dysplasia 4 9 2.2529190867976747 0.0242642511699926 2.6990291262135924 7.878640776699029 0.934970332417222 0.3353928049199215 1.4834684590696818 1.182325377441881 0.8740525348763903 0.2730031671079428 1.0 1.0 0.2030300441679912 0.017764157863851 0.0043704316922178 +Abnormality of the tongue 17 99 2.250130360191483 0.0244406713494098 22.424757281553397 89.52912621359224 0.5421010507218363 0.5607339999720974 6.938472222740965 9.436122816051313 0.9593463898963266 0.3606735981467843 0.0697240995373476 0.740817890060099 0.0050691064660699 0.0009908214482926 0.024025396868752 +Cardiomegaly 10 35 2.2498332396934124 0.0244595331243888 8.490291262135923 34.762135922330096 0.0974375624133147 0.5220140632172088 3.5269287104729803 2.3403848536252574 1.0599377415868538 0.3263143509209658 0.0056701427298803 0.0090901991927659 0.0016898291272514 0.0002844112557687 0.0035274529804402 +Facial hypotonia 1 10 2.2468568384811825 0.0246491778847057 3.0728155339805827 10.716019417475728 -0.1881823532146107 0.5709644623686712 2.0761097944457676 1.2750159639631284 0.8616316082230207 0.3072754177969913 0.0310394603318191 1.0 0.0435975481844182 0.2012424218570439 0.4989028149926751 +Unusual infection by anatomical site 3 14 2.246720745928615 0.0246578795454706 3.907766990291262 13.49271844660194 0.7293808434681487 0.4605880442375236 1.9820157102817233 2.372464489866843 0.7897149485111757 0.3081613942392058 0.3195763160296334 0.2067156970649581 0.0774589481602222 0.1067440658746814 0.1947782280968408 +Platyspondyly 8 34 2.245739440108836 0.0247207023507007 8.28640776699029 33.730582524271846 0.6662607465302498 0.4948187493576657 3.3732974430890796 4.074278380383408 0.9978722835718216 0.3450714604006198 0.0299940149088271 0.3361355940595682 0.047891776654715 0.0009186761927776 0.0193099294165308 +Orthostatic hypotension 2 13 2.2414111740824008 0.0249994533761794 3.6262135922330097 14.315533980582524 0.2234754096973065 0.4106322335953559 1.878879089774009 1.367959097892007 1.1506876393484995 0.291561214686976 0.2048067767459769 0.1287528218161406 0.0305060181117638 0.0300655360870906 0.1539585868211262 +Hyperintensity of cerebral white matter on mri 4 21 2.238948752072893 0.0251592508508882 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 0.0004718739175282 0.0204019662414969 0.0009534889418974 0.0045948289685349 0.0664883963333954 +Abnormal urine cytology 4 39 2.2374035379754185 0.0252599775170179 7.905339805825243 38.74029126213592 0.1397968004380557 0.6345678609070249 4.377598604797632 3.4861762947224593 0.775500557033054 0.3063073533495467 0.0539615299706925 0.093603257631803 0.0195932975716513 0.0434375027766798 0.139715187901143 +Progressive spastic quadriplegia 1 8 2.2342237553788884 0.0254683541355156 2.6407766990291264 8.094660194174757 0.8041722661618813 0.2980182786117089 1.3079619433616207 1.0302561803519357 1.23715789109981 0.2930725496255146 0.0028240506634377 0.0479914252810258 0.004071454093033 0.0234889728544392 0.010684483318579 +Abnormal midbrain morphology 3 12 2.23164262572674 0.0256385920352275 2.155339805825242 7.762135922330097 0.7338155730112543 0.3990028707572332 1.3492700763379188 1.674109907241791 0.9359553327569134 0.2948227663961126 0.3984836434715033 1.0 0.1235163706059048 0.0645029072929147 0.1837162306077457 +Abnormality of the ribs 12 66 2.230981369961982 0.0256823630924558 15.46359223300971 63.26456310679612 0.6596881680500318 0.4822792711086646 5.162987649103379 7.327989071924885 1.0464354559452582 0.3722680363619953 0.0846190597046506 0.2643557331790067 0.1402699688168154 0.0114548238913975 0.0733827537651485 +Abnormal heart sound 2 6 2.228554014204934 0.0258435936572745 1.6262135922330097 5.065533980582524 0.0895700854459297 0.4481870945716114 1.1828434692827956 1.0014923118961363 1.1311355032809087 0.3141022336032418 0.0230572634873926 0.1330370821365251 0.0325598174288622 0.0329460998536745 0.1659016353191164 +Delusions 3 20 2.225508706169941 0.026047107326595 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0327496360061982 0.1583124314184509 0.0459506122728715 0.0100334254948701 0.0063226090272968 +Elevated pulmonary artery pressure 9 27 2.2197756326888136 0.0264340018036595 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.1635242481649697 0.0704839558103872 0.0567924573004668 0.0059914172581948 0.0111044401007954 +Blindness 14 84 2.2187707016656866 0.0265023282091099 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 0.0055683384589375 0.0736360802948869 0.0007335550889116 0.003515877849672 0.0337869858447665 +Prolonged neonatal jaundice 2 18 2.2184930190692262 0.0265212350482542 4.946601941747573 18.174757281553397 -0.101310924906929 0.5918835161037648 2.7336563066184225 2.809232989559863 0.8382795367545739 0.2869314667709456 0.0047509494145314 0.1868885334554594 0.00796664232011 0.0824073873197279 0.1466332856037892 +Infantile axial hypotonia 3 10 2.2160502911415096 0.0266880580735455 3.0970873786407767 9.91747572815534 0.2141703344813526 0.3664899290512883 1.6385203075306134 1.5973234399272347 1.21609252960959 0.2741067096589152 0.0018022058235508 0.1373006943976843 0.0030667784637357 0.0057743966142769 0.0560616912320164 +Avascular necrosis 5 23 2.20567669971884 0.0274066444755092 5.070388349514563 21.203883495145632 0.6420454351604097 0.3947374085674277 2.2614105153836106 2.2592172512550373 1.1319127818663337 0.3183649666305153 0.0784025564630051 0.2449590299452383 0.0182749379957494 0.0025564989720558 0.0060616304531859 +Skeletal muscle hypertrophy 9 46 2.1969374111018385 0.0280249165316659 9.978155339805824 43.95873786407767 0.2882267398053342 0.5822719825831179 4.164926192558732 4.192080647433412 0.9226697759716594 0.3424177343120818 0.0224771937120527 0.4795806297081992 0.0095229572911991 0.0050022469325498 0.1102476902143204 +Increased blood pressure 11 74 2.1934270172802943 0.0282766275410843 14.75242718446602 72.72572815533981 -0.0838526898771034 0.6483550700417918 5.81568593088035 8.647072471875523 0.7817693388204221 0.3145908447533387 0.3575560809910112 0.1357113467114961 0.1133593840721368 0.0264761399240129 0.1367674850692352 +Abnormality of femur morphology 15 71 2.191650611699865 0.0284047444484996 17.20873786407767 66.68203883495146 0.8363246416857221 0.4265359075043799 5.791282481104246 7.777760660479065 1.2398669594969238 0.3848538433547022 0.0212286417125704 0.0701955688763637 0.0426132658625168 0.0002990287462504 0.0068705709277622 +Ventricular arrhythmia 6 41 2.191616166975921 0.0284072335854037 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.0013606920500565 0.0876325329480415 0.0030917023376328 0.0117065019059818 0.2219073979752139 +Neuronal loss in central nervous system 2 15 2.191269530975096 0.0284322935873373 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0245754818920448 0.1373006943976843 0.0346664630686661 0.0359651779911995 0.0560616912320164 +Abnormality of lipoprotein cholesterol concentration 2 15 2.1910889615707654 0.0284453553701413 3.594660194174758 13.79126213592233 0.146670453757452 0.3159030988618912 2.0804850608489107 1.8940687593815968 1.3545369944331518 0.2589389983473483 0.0245754818920448 0.1373006943976843 0.0030667784637357 0.0359651779911995 0.0560616912320164 +Multifactorial inheritance 3 14 2.190048177012604 0.0285207430286227 2.8470873786407767 12.20873786407767 0.2163196238382478 0.6167290651157903 2.134646298009975 1.5964527909741115 0.7740633808165153 0.2982305852514722 0.2048067767459769 0.1287528218161406 0.0305060181117638 0.0044816860022438 0.0451666412494461 +Bilateral talipes equinovarus 2 5 2.178854599523664 0.0293424713729533 1.2160194174757282 5.072815533980583 0.5190331925889594 0.4052637886709829 1.0991769558198925 1.20659145801502 1.0429198424686923 0.2748805198506031 0.0934764824591146 1.0 0.0058956460302812 0.0026887292270871 0.0182159139614431 +Eyelid myoclonus 2 10 2.177820562854453 0.0294193983808821 2.004854368932039 9.531553398058252 0.5187806868364082 0.4301345640798078 1.347408778242444 0.9835908626114443 0.9516679014482394 0.2768543779231988 0.2241232989350378 1.0 0.2636091346473535 0.1746199077901094 0.1905468417868487 +Abnormality of the alveolar ridges 3 7 2.177236267676719 0.0294629436034521 2.1092233009708736 6.368932038834951 1.3424122348723253 0.2105791674194365 1.182482323454481 1.3741037061958896 0.9200079991465796 0.2386077675723682 0.2112978307962688 1.0 0.0027797273347076 0.0051006501172469 0.012132108209414 +Perseveration 2 9 2.175910717881655 0.0295619372258935 2.228155339805826 7.747572815533981 0.2549642857282638 0.5145676770156781 1.6269524477167985 1.327223882767772 0.9406545169811942 0.3029494680332692 0.1298272630870375 0.0802348466038066 0.0117676307173903 0.0635022977163126 0.0470360579614364 +Barrel shaped chest 3 5 2.1748229021355323 0.0296433901727564 1.674757281553398 4.473300970873787 1.1869997902874323 0.2609030887925388 1.0385967424919742 0.917344085691108 0.8975397916941404 0.2534223349008651 0.1081933924999157 0.066549445548378 0.1289666473793992 0.0002865546760543 0.0037759888499611 +Undetectable electroretinogram 2 5 2.171978115450865 0.0298573136529496 1.7427184466019416 4.415048543689321 1.0664751707047182 0.1916317897201908 0.9612998826677368 0.7632752290710167 1.383034454070232 0.2429274936147374 0.0048180551758565 0.0017760204843955 0.0002437892001771 0.0034327477034809 0.0228394808772788 +Arterial stenosis 3 14 2.1697762872145496 0.0300237975843149 3.703883495145631 14.097087378640778 -0.1012288199392378 0.6674696362750959 2.243585130734692 2.232872515836187 0.6964074865780938 0.2833589826178254 0.0930363205394527 0.2670314735990955 0.0237837250606552 0.0676165417704692 0.3690218081573729 +Abnormal ldl cholesterol concentration 2 14 2.159514939223972 0.0308102395999509 3.3907766990291264 12.616504854368932 0.1598459071865069 0.3035988995241804 1.922077248743316 1.8231306205769169 1.371220486686296 0.2515253044142337 0.0187491014912179 0.1201219647894398 0.0020204438885922 0.0247234076565489 0.0355737118947821 +Abnormal large intestine physiology 2 20 2.1510052912584774 0.0314757820463384 5.104368932038835 20.50242718446602 0.3008286810865617 0.501154789704215 2.3382177969194613 2.943232146467361 0.9913296101531662 0.3267316971730095 0.0559096038955752 0.0221396463904123 0.0774589481602222 0.1067440658746814 0.1947782280968408 +Disproportionate short stature 7 26 2.1508957899815884 0.0314844259193305 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.5183971162381186 1.0 0.2171594264364444 0.0014512659904693 0.0289723687417025 +Abnormal endocardium morphology 4 16 2.150446569328244 0.0315199080644723 3.766990291262136 14.5752427184466 0.4111751310040221 0.5391262081434103 1.9531099596461143 1.4352255968673668 0.8293137150283321 0.3006328742463684 0.2910660683117588 0.1868885334554594 0.0636449972198752 0.0033942963153933 0.0520328360234653 +Cirrhosis 6 38 2.1492584127771 0.0316139211764865 7.813106796116505 38.04126213592233 -0.1452161322848621 0.4839588586854018 3.471314216064694 3.703939959360424 1.1276079613645364 0.3330627717006385 0.0421826517474328 0.078908455169182 0.0140469368115112 0.0084996601315941 0.041601757725466 +Abnormal biliary tract morphology 4 23 2.148488560706741 0.0316749641735434 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 0.0690993947194993 0.027703186905031 0.0951370618475993 0.0092216123798009 0.043045103354355 +Visual loss 9 53 2.1457907401096024 0.0318896777511543 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0382041631400203 0.007032737188996 0.0042602902765784 0.0142430684063797 0.1398224860007888 +Heterogeneous 13 44 2.1419258725043595 0.0321994475299116 10.235436893203884 42.58009708737864 0.5995354724013603 0.4531415918363276 4.134323127398932 5.0637577656341985 1.0306945905630256 0.3367867805298957 0.0259459780596812 0.029947979425984 0.0113995491624377 0.0197699662563586 0.0010885129199153 +Neurofibrillary tangles 2 5 2.1359242500385323 0.0326855886374555 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 0.0001774834639225 0.0020655426456597 0.0003080716102714 0.0042908003473226 0.0037759888499611 +Hyperlipoproteinemia 2 11 2.134581204582231 0.0327952340737027 2.4902912621359223 9.300970873786408 -0.2334402023779523 0.3281082864585681 1.5602473393108425 1.5443913650600527 1.2897346825889175 0.2523514437001098 0.0113114865314974 0.0937235599037543 0.0009244711113057 0.0120645849010356 0.0708751155690715 +Increased ldl cholesterol concentration 2 11 2.134581204582231 0.0327952340737027 2.466019417475728 9.092233009708735 -0.2239097220499274 0.320127491790266 1.5379694972203586 1.5316207115206113 1.3088687012404925 0.2512376917026361 0.0092050279194046 0.0847528009868792 0.0006712136127385 0.0089509329804495 0.0544656750173612 +Recurrent skin infections 4 20 2.1333895419879907 0.0328927842446986 3.8762135922330097 14.419902912621358 -0.0929914883044618 0.6374328687097303 2.8158216709397097 2.2144477034580747 0.7248321552407455 0.2788775621452306 0.0784025564630051 0.2449590299452383 0.1075014480598519 0.1623088290800169 0.143641072876532 +Abnormality of pulmonary circulation 9 31 2.1331570743606 0.0329118431055497 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.2164712900591845 0.0966324665930835 0.0877302870164678 0.0157092440877508 0.0355554422706211 +Intestinal polyp 0 18 2.131533402990095 0.0330452236221974 4.274271844660194 19.40776699029126 0.2353302452404326 0.6680662950816225 3.2027018635944486 2.607632163305349 0.6382199307676231 0.2804206802572125 0.3575967580900071 0.2336798458054532 0.4135270958140081 0.7378001234946985 0.933179374802002 +Abnormal lower motor neuron morphology 4 10 2.1312929232166207 0.0330650177160711 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.1850152793775121 1.0 0.0018000470176383 0.0222629680099487 0.0063685282240186 +Angina pectoris 2 5 2.128873962522007 0.0332646895193069 1.327669902912621 4.009708737864078 0.5754052050374406 0.3094934726297071 0.9887284212744736 0.8894761808679401 1.2599650807227574 0.2579742849945131 0.0102339970863349 0.0038211367015083 0.0146091852998709 0.0104402688493973 0.0624183143373935 +Cognitive impairment 25 174 2.126287657443688 0.0334793151170278 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 2.853414299613828e-06 5.316163123383402e-05 5.8798213897175173e-08 3.883945465198223e-05 0.001219926291732 +Coxa valga 6 23 2.125405009859905 0.03355283261555 5.245145631067961 19.95145631067961 0.3761170106319844 0.4485543113651226 2.6522752145550523 3.395824508532713 1.0354006500412785 0.2987185055269495 0.0151748347862839 0.270648213584465 0.0247799010891251 0.000903148993151 0.0120813031454948 +Aortic valve stenosis 2 10 2.1210591189127603 0.0339168276683166 2.796116504854369 9.395631067961164 0.7980634307089747 0.2889050866980456 1.488527149166336 2.3205038664019155 1.1792618257802154 0.2672367246557839 0.2968609783283818 1.0 0.3460310778663031 0.0870629174096409 0.1558648118264061 +Recurrent bacterial infections 7 23 2.1199476183535944 0.0340104630007604 5.436893203883495 18.847087378640776 0.0115599015584955 0.6014605464611277 3.463176337961712 2.7285645186014564 0.8506926330324409 0.3001404261676266 0.0338163079731626 1.0 0.0537433156025904 0.1632106984779044 0.0611194570858546 +Diplopia 4 22 2.116473340145927 0.0343045702841366 4.759708737864078 19.759708737864077 0.1260996986004586 0.6575168692920278 2.7043704133572564 2.5671615379185453 0.7043606761923874 0.2798538828984989 0.3469532683251365 0.2260688267312995 0.0921147949975289 0.0085171031160944 0.1079287008920704 +Atrophic scars 1 8 2.115994026458201 0.0343453156227375 1.885922330097087 6.512135922330097 0.5685434576691318 0.3662510848055916 1.2401440073700836 1.3264846238284391 1.0819526112515987 0.274421474936134 0.0160900301160464 0.1114073342812727 0.0228441699597423 0.1154739846724814 0.3280048671308403 +Delayed fine motor development 3 10 2.112395236222155 0.0346525632643515 2.45873786407767 8.847087378640778 0.0522995867846302 0.5597228848853018 1.6267623331532826 1.6320266340083258 0.8779555463846763 0.2976557667806174 0.1783105780413945 0.1114073342812727 0.2108642126213972 0.0199432580741765 0.0272826327042602 +Fasciculations 11 40 2.111296200159751 0.0347468604571601 9.201456310679612 36.5 0.4731561459207285 0.4826265043963199 3.4648999783170837 3.557775567723639 1.0532476984865673 0.3454376907067654 0.0192581415930694 0.046072228335376 0.0005997641678419 0.0015399081103358 2.767901903609281e-05 +Abnormality of the upper respiratory tract 13 101 2.109078092439889 0.0349378415040038 19.66504854368932 95.80582524271844 0.4534569687157453 0.5959175600884278 6.924659870205313 10.36312380503997 0.9632839800839448 0.3651113920771414 0.0102390981425996 0.0565240228775174 0.0084884289049757 0.0296600289329144 0.0868406761305628 +Meningitis 1 6 2.100085133352111 0.0357213528531115 2.179611650485437 6.274271844660194 0.789971069936712 0.3622376484019577 1.3480557177345056 1.3864875660317604 0.9776190102947984 0.2839276823170232 0.2177365324780222 0.1373006943976843 0.0346664630686661 0.1658780833937837 0.4336067804253886 +Emg neuropathic changes 2 22 2.098939215379093 0.0358222593653312 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 0.005770728097185 0.0204019662414969 0.0096414106757913 0.0966974979109908 0.174947649934789 +Chronic pulmonary obstruction 0 6 2.098873590021117 0.0358280455133015 1.7912621359223302 6.975728155339806 0.7151400882135658 0.3422892186915894 1.3201652438579738 1.3051032038511063 1.0511250125541778 0.2765518721331778 0.1509425000049774 0.0937235599037543 0.179062604831997 0.3904027877902372 0.6322714034398937 +Abnormality of skull ossification 4 14 2.0978949852639284 0.0359144231073385 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.2429761091428759 0.1541506060207377 0.2851312580635185 0.0013008093576653 0.0010690688695759 +Oculomotor apraxia 15 29 2.0872306906228046 0.0368672864856622 5.648058252427185 24.56553398058253 0.4636956319177163 0.5717143314512599 2.6876056974482267 2.699887889853458 0.7708144058365661 0.3119126109104529 0.1380746617495529 0.0584635742500571 0.0437228444640497 0.0457163514521504 0.094428031243587 +Increased circulating lactate dehydrogenase concentration 1 13 2.084340518302608 0.0371292042100226 3.1092233009708736 14.009708737864075 -0.0898359396000094 0.4215562670860733 1.75300363001213 1.740411432392157 1.117422097583478 0.2860320368252682 0.2177365324780222 1.0 0.0346664630686661 0.1658780833937837 0.4336067804253886 +Abnormal visual fixation 3 7 2.0785965330047587 0.0376544499179145 2.1237864077669903 6.516990291262136 0.3282606812074232 0.2644845064785266 1.2333226229346623 1.2136771814929264 1.4687997702265556 0.2650474123539905 0.0092050279194046 0.0847528009868792 0.0131546828557762 0.0008110696558398 0.0098879726868235 +Pedal edema 2 7 2.075754173929312 0.037916692689897 2.092233009708738 7.211165048543689 0.6115824815809859 0.289867756561444 1.3297338459429695 1.219410808682535 1.3115580791228945 0.2762999280116011 0.191665926491972 0.1201219647894398 0.2263045436956677 0.0247234076565489 0.1309583783231107 +Subcutaneous nodule 2 17 2.072774629132652 0.0381932586317634 5.174757281553398 17.716019417475728 0.7715929851765809 0.3892857335439222 2.3624373807533945 1.5246949972287631 1.0645096840549642 0.3076166958299045 0.0713888723716441 0.2336798458054532 0.0158208073938894 0.1448032950165304 0.2686893480606078 +Confusion 5 19 2.0702985453960467 0.0384243957279559 4.924757281553398 17.62378640776699 0.5770193034786405 0.489615172337713 2.480343831732211 2.1535063377225914 0.8853427180085949 0.3168581188371634 0.0559096038955752 0.2067156970649581 0.0108633849740392 0.0272622697998741 0.0256439269364036 +Abdominal pain 8 81 2.069014210114852 0.0385447532525209 16.96359223300971 83.16504854368932 0.3964756684912572 0.6430718197673689 7.055682465717051 7.337689760207977 0.7784486666855822 0.3354599982921351 0.2397796005485705 0.0816493973548617 0.0535415398559931 0.0689090828353692 0.3154768182111067 +Middle age onset 2 11 2.067112675519581 0.0387235379831931 2.3567961165048543 10.058252427184469 0.2336229973862058 0.5304493567741497 1.7477801252441654 0.9661779642543156 0.8480559321463624 0.276826590957438 0.0148267428903527 0.1070183553885475 0.0210734332562196 0.017764157863851 0.09905667817091 +Inappropriate behavior 2 18 2.0658609251628564 0.0388416133531561 4.111650485436893 16.885922330097088 0.1384539200488892 0.5568708768969491 2.346689507546719 2.02390948073287 0.8632293435648196 0.2961880037432384 0.0456983473100118 0.1868885334554594 0.00796664232011 0.0824073873197279 0.0520328360234653 +Postaxial hand polydactyly 8 17 2.0608729775082306 0.0393151599176111 3.5388349514563107 12.196601941747574 0.7545932459489302 0.4236334481994441 1.874961903028305 2.911758569621324 0.8289474601419616 0.2879125852873546 1.0 1.0 0.5377799970023095 0.0028785511504589 0.0132476040767509 +Cheilitis 1 6 2.0597115786799263 0.0394261218441374 1.9150485436893203 4.036407766990291 -0.681022701867273 0.4175846266840705 1.2307022021045015 1.1642467912807983 0.979646464594008 0.301176414936982 0.0048180551758565 0.0619434524836269 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Hypohidrosis 2 9 2.05789726630151 0.039599996224505 3.094660194174758 9.514563106796116 -0.4756466337815434 0.4523993517066125 1.8560503610582415 1.4455427150946332 0.9891348536021548 0.3071923224725194 0.2552924739487913 0.1624541869963563 0.0483495219963649 0.0569111676931314 0.2554523730097116 +Cardiac arrest 5 35 2.0563890465507733 0.0397450312447087 6.805825242718447 30.883495145631063 0.2033061782403586 0.6221461087652603 3.558275606223926 3.756679412878012 0.8139232597509225 0.305898290763257 0.0247174585723989 0.3161039234082394 0.0068221584627764 0.0026746302438548 0.0333177078736064 +Focal non motor seizure 2 11 2.0560883507256107 0.0397740009046323 2.779126213592233 9.473300970873789 0.0084656133548897 0.6464403812634476 2.065023381609613 1.237271417233086 0.6882627629188746 0.2666918927057338 0.2793343331559579 0.1788224008957527 0.3263246311566628 0.2555664496894125 0.3092787829323835 +Hydrops fetalis 7 43 2.056035219264533 0.0397791215621694 10.383495145631068 42.85436893203884 0.0422302936304952 0.5660977362192432 5.636524390210048 3.6334683929983864 0.9704238719472263 0.3260500973307448 0.0348097020403367 0.3523884632837075 0.0552577125191105 0.0056343267091593 0.01028970028679 +Aplasia hypoplasia involving the vertebral column 4 15 2.052113588295749 0.040158624672177 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 0.0476798475193373 0.1908924307699622 0.0663348012473392 0.0037658297098364 0.0171255123594616 +Abdominal distention 3 23 2.051818345851077 0.0401873196855946 5.485436893203883 22.050970873786408 -0.0003338754339785 0.4183345800599354 2.797759428334228 3.5457925331964995 1.149073376880733 0.2861614172485306 0.4813146908943624 0.326192706464958 0.1849845964283991 0.1315761252418354 0.3508942766396105 +Recurrent bacterial skin infections 3 5 2.05040349707324 0.0403250722194363 0.9393203883495146 2.1480582524271843 -0.2974533292028328 0.4733169027452826 0.6993113979708095 0.8418202172435947 1.31519603918757 0.3502229875945362 0.1226742139485862 1.0 0.1459927402947744 0.0569248849368824 0.0063533232968262 +Abnormality of skin adnexa physiology 6 41 2.047284641388532 0.0406301450019128 10.475728155339803 41.90533980582524 -0.4059059261308879 0.6040498024970644 4.977316819554185 4.6166930785595195 0.7738283426447101 0.3175601635292085 0.2586407265060255 0.1185798153291669 0.0309622376784825 0.0757785059975643 0.3767361514168116 +Emg chronic denervation signs 1 12 2.047089474737256 0.0406493002176842 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 0.0160900301160464 0.1114073342812727 0.0228441699597423 0.1154739846724814 0.1093101132411038 +Vertebral compression fracture 3 18 2.042003513850758 0.0411511827770174 3.718446601941748 15.771844660194176 0.638605685637545 0.4585378455721924 1.8270750975800616 1.3728941491613926 0.8197174983565503 0.2921971535023096 0.191665926491972 0.1201219647894398 0.2263045436956677 0.0033995973847004 0.0012998754323988 +Abnormality of humoral immunity 8 59 2.040548164794768 0.0412957589406404 11.274271844660197 56.02669902912621 0.2236266828854534 0.674955898838158 5.483870276333484 5.712935906905208 0.7522335434112123 0.3241379607555358 0.0382041631400203 0.1778097782829715 0.0670588556929843 0.1822830702553526 0.2301678128932489 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13.82766990291262 0.3069722257003373 0.4002472963954175 2.1227792341357876 2.102220603041329 1.0976485702648275 0.2780557299464236 0.0538078303441176 0.0212633176973237 0.0746250944081647 0.0254140783095469 0.0717558982580182 +Abnormal lactate dehydrogenase level 4 18 2.02517586297021 0.0428493092184671 4.143203883495145 17.87621359223301 -0.1889046507521062 0.4455642582293665 2.002759607594022 2.089436499733168 1.1284322896017482 0.2992123479577444 0.3251409200185139 1.0 0.0803264485176453 0.0291888164392555 0.0829547176041151 +Abnormality of the 5th toe 6 12 2.0246929140981877 0.0428989066888247 2.9223300970873787 8.259708737864077 1.1073405288994291 0.2882520454965396 1.560677724258624 2.165041741031587 0.9522253135241228 0.2721172964763348 1.0 1.0 0.4363210249842685 0.0133513277547448 0.0219335059982234 +Postaxial foot polydactyly 6 12 2.0246929140981877 0.0428989066888247 2.9101941747572817 8.179611650485437 1.1164564935210708 0.2854713626620553 1.5514456024758956 2.174827712105029 0.9565986562813577 0.2724819159224514 1.0 1.0 0.3714211816154574 0.0055460197819823 0.0072430636656091 +Biliary tract abnormality 4 26 2.022979296347671 0.0430752821092728 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0955479813724685 0.0391768542263283 0.1300768221953693 0.0197625026052712 0.0906618761530448 +Macrogyria 2 6 2.0154062178163783 0.0438621034774142 1.5024271844660195 5.648058252427185 0.9880312678764684 0.314713035809367 1.057793055191099 0.9137148736849272 0.850980571286911 0.2493075505833739 1.0 1.0 0.1951188871774342 0.099708835751112 0.0892170338783466 +Bone pain 5 21 2.0134350208421505 0.0440688844573118 4.975728155339806 22.203883495145632 0.6350188771758896 0.4127751797545932 2.519707411717398 2.310210444333206 1.0375367125895096 0.3016728005813124 0.0690993947194993 0.027703186905031 0.0951370618475993 0.0400103397181721 0.0138300064936424 +Abnormality of the autonomic nervous system 9 51 2.013377870827345 0.044074891818242 13.00485436893204 55.26699029126213 0.3670512850033909 0.5541466916846621 4.587866620164831 7.685983818115474 0.9605273369537758 0.3522477471453715 0.2013626772501697 0.0660022239528654 0.1163661783407936 0.1832723486519353 0.4481084986123512 +Abnormal leukocyte physiology 8 65 2.0126157883546303 0.044155064704809 12.00728155339806 62.28398058252427 0.2079341111276809 0.7071752426147094 5.830739215100783 6.432203240250949 0.7011486106506812 0.3175728838622644 0.0496911623024371 0.2026710555234917 0.0857565820507106 0.2360736878493645 0.3163302096033431 +Sparse body hair 5 12 2.006403321721796 0.0448132342111169 3.342233009708738 10.08252427184466 -0.3030063928435675 0.4907312013716142 2.1342930127217956 1.1418709893008905 0.9575476201653794 0.2935588277766331 0.00118147877086 0.1201219647894398 0.0020204438885922 0.0003605515781946 0.0012998754323988 +Thickened skin 14 108 2.0063611507300245 0.0448177300685148 22.009708737864077 100.32766990291262 0.4385550996860712 0.6098739890089617 6.832596267878453 10.09935648280444 0.8592900670649001 0.3543867989618216 0.006447569535115 0.0432872408847351 0.0170335461122621 0.0026596686673569 0.024025396868752 +Endocarditis 2 6 2.004126310939889 0.0450565316223214 1.6699029126213591 5.055825242718447 1.0315066990472646 0.3137673633075574 1.128951309195931 0.7031759081548564 0.9300019606367588 0.2935479974969262 1.0 1.0 0.1116045715736199 0.0026887292270871 0.0182159139614431 +Recurrent respiratory infections 18 132 1.99953509896782 0.0455504881523605 25.609223300970875 121.247572815534 0.0941290126879241 0.6911276937216804 9.844431296528938 12.211401203444838 0.8452074084239468 0.3237848271674418 0.0017867400145096 0.0254310510346749 0.0018779004123337 0.0205793512768054 0.1631949984927564 +Flared iliac wing 3 7 1.999340479900228 0.0455715271356433 1.364077669902913 5.334951456310679 0.5405486604626366 0.4179648529865938 0.9746649281279828 1.0213458413978087 0.9547768473806943 0.2811422579068001 0.1154630790463651 1.0 0.1375212864755611 0.0003832983840783 0.0049531384619904 +Joint swelling 1 7 1.9962276556110723 0.0459091484814861 1.6650485436893203 6.740291262135922 0.3109744271340265 0.4064008040369078 1.2500259211187394 1.1979059044612257 1.115547263835383 0.290400539923086 0.1509425000049774 1.0 0.179062604831997 0.0846217526668656 0.2546657991273667 +Abnormal femoral neck head morphology 9 47 1.994307755922345 0.0461184321745362 11.097087378640778 44.88834951456311 0.710356821644891 0.4647128189516342 4.081724752298962 5.521112188696193 0.9531654138623804 0.3489729073692786 0.0847137862779167 0.4664619130311752 0.1286355874014914 0.0010778332129242 0.0209466710807101 +Gait ataxia 8 73 1.9853395739155544 0.0471067039296486 14.351941747572816 68.35194174757281 0.6787136514518399 0.4783255809544575 5.256980668043156 6.678826209042067 1.046898326537344 0.3693668840587258 0.0022150605048207 0.0085414395311053 0.0011605386558807 0.0198305799367777 0.1817646493603847 +Abnormality of lysosomal metabolism 2 5 1.9852887151911327 0.0471123588396857 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.00227122160607 0.0432957136582515 0.0032780640178306 0.0190953097419897 0.0077568745967145 +Anarthria 1 7 1.9844076263358967 0.0472104165405808 1.3131067961165048 6.509708737864078 0.7919989281491029 0.3725746548429688 1.0710321028305447 0.7679267970658434 0.9858894880388938 0.2988917867777952 0.100864684735291 1.0 0.0069232563631819 0.0388074443523606 0.1297945989547683 +Mesomelia 3 8 1.982361759048232 0.0474387663761448 1.733009708737864 6.512135922330097 0.3881302362797289 0.5294186835797253 1.326202575683821 0.8460922744387435 0.8812258650629952 0.3075560327587827 1.0 1.0 1.0 0.00251045639703 0.0272826327042602 +Scarring 3 31 1.980304581096014 0.0476693143555329 7.41747572815534 30.87378640776699 -0.1258492688784176 0.6582841673370581 3.825119509129044 3.6852622033956304 0.7192518810653888 0.2892438224654526 0.0539615299706925 0.4047844567784328 0.0195932975716513 0.2545314791993786 0.5857606775270319 +Corpus callosum atrophy 1 16 1.9777669724860585 0.0479550009971263 3.8907766990291264 14.728155339805824 0.1983845931768132 0.4648037373286657 2.580775148596329 1.1570314775092398 1.0666401582531118 0.3051438618178521 0.0113114865314974 0.0937235599037543 0.0161297090986061 0.0846217526668656 0.2546657991273667 +Abnormal circulating copper concentration 2 6 1.9774341348907136 0.0479925787183885 1.8422330097087376 5.575242718446602 0.7192357902216235 0.3771156375814327 1.260629702441343 1.0104640332277932 0.9717173289058264 0.2836036003591781 0.0633191306420368 1.0 0.0758460972151271 0.0150927838189798 0.0053637976870067 +Abnormality of ocular smooth pursuit 5 23 1.97727565639858 0.0480104798037643 4.682038834951456 21.37864077669903 0.0972872224819478 0.6513359289956454 2.6381016487564417 2.4440000033939624 0.6867806254805304 0.2771147721624212 0.0073202198372533 0.2145132052110039 0.0121710399777804 0.0311941867040692 0.03080273588529 +Hyperkalemia 2 6 1.9654755810774085 0.0493592192225751 1.300970873786408 4.606796116504855 0.0827950259466108 0.5748873450366397 1.1519080958512211 1.0953353997945885 0.853963314238104 0.2881176737562291 1.0 1.0 1.0 0.0333651833289618 0.0182159139614431 +Coronary artery atherosclerosis 1 5 1.9647212921865929 0.0494465041871841 1.6553398058252426 4.014563106796117 -0.4144574634725804 0.4762357228627029 1.1417265205112812 1.0679721976482213 1.0168657616849337 0.313346587522578 0.0187491014912179 0.1201219647894398 0.0265618978442646 0.1318172807011351 0.3640245481081547 +Aspiration 1 11 1.9609164981017515 0.0498887644383336 2.6699029126213594 9.79126213592233 -0.0172085582186148 0.5174459915750989 2.0521754950341604 1.2464011724725987 1.0157484074741647 0.3174080591477043 0.0092050279194046 0.0847528009868792 0.0131546828557762 0.0703212183088513 0.0544656750173612 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ded576d30fa85e3940bb4447928966420d5b0e7a --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 4610, + "title": "Average number of proteins per term", + "value": 24.55531453362256 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ca809bbef2f7a7904c52c2d01f2de1ab20fca2d --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1e666189ba92da0a6aa7c12a8743025d72334cda --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1540 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Splenomegaly 0.714876330204904 4.1719593331347395 3.0199154380072812e-05 0.1299635780234527 0.1392181016921402 87 P15586,P61916,P07602,Q14108,P04066,P54802,Q14739,P10253,O00754,P16278,Q13510,O15118,P28070,Q15904,Q10713,P38571,Q15392,P01889,P04062 19 +Corneal opacity 0.706899219468571 3.4262390414621926 0.0006120015234267 0.9405244933197866 0.2290535679525762 61 P34913,P04066,Q13510,P04062,P01130,Q9P273,Q9ULC3,O43505,Q9UBM7,P06280,Q14118,P10619,Q15056,O00754,P16278,O75844 16 +Abnormality of the spleen 0.6480658940684102 3.4030072827721827 0.0006664850398767 0.9537419777178864 0.2290535679525762 122 P15586,P61916,P07602,Q14108,P04066,P54802,Q14739,P10619,P10253,O00754,P16278,Q13510,O15118,P28070,Q15904,Q10713,P07686,P38571,Q15392,P11166,P01889,P04062 22 +Mental deterioration 0.6286038480134982 3.3807498467804846 0.0007228832149663 0.9643389671418888 0.2290535679525762 100 Q14108,Q13510,P04062,O15118,P54802,O75503,P61916,P02792,P05067,P07686,P50897,P16278,P17900,P07602,Q9NUM4,P06865 16 +Diarrhea 0.6406024681446666 3.1833630433996705 0.0014557496294536 0.9987884991422854 0.2290535679525762 73 Q6YHK3,P42892,P01889,Q13510,P15586,P54802,P06280,Q15904,P07686,P38571,P02786 11 +Abnormality of the vasculature of the eye 0.6237926308699436 3.0516319673699077 0.0022760097485474 0.999972583444108 0.2290535679525762 73 P04439,P01889,P04066,Q13510,P28070,Q14739,Q96PY6,P06280,P10619,P07686,P16278,P02786,P17900,P07602,P06865 15 +Loss of speech 0.8292496796025121 2.972248918116742 0.0029562689947999 0.9999988183330708 0.2290535679525762 21 O15118,P61916,O00754,P50897,P17900,P07602 6 +Arteriosclerosis 0.8805269249663092 2.9674756856765576 0.0030025602948613 0.999999046021854 0.2290535679525762 16 P34913,Q13510,O15118,P01130,P61916,P38571,P16278 7 +Dementia 0.6426514920616763 2.9340872413504084 0.0033453016548281 0.999999804497693 0.2290535679525762 59 Q14108,Q13510,O15118,P61916,P02792,P05067,P17900,P07602,Q9NUM4,P06865 10 +Abnormal systemic blood pressure 0.5667821666870521 2.9009714903750012 0.0037200772234777 0.9999999654733438 0.2290535679525762 92 P42892,P01889,P04062,O94898,P01130,Q13423,P06280,O00170,Q10713,O43772,P07686,P38571,O75844,P07602,P10644 15 +Abnormality of the lymphatic system 0.603472062494395 2.8771269845478353 0.0040131406431938 0.9999999911052152 0.2290535679525762 145 P15586,P61916,P07602,Q14108,P04066,P54802,Q14739,P10619,P10253,O00754,P16278,Q13510,O15118,P28070,Q15904,Q10713,P07686,P38571,Q15392,P10644,P11166,P01889,P04062,Q9ULC3 24 +Abnormal heart valve physiology 0.5596698985721399 2.86084277405798 0.0042251653178568 0.9999999966666142 0.2290535679525762 89 P01889,P19022,P04062,P01130,Q9ULC3,Q96PY6,P06280,Q15904,O00170,P49459,O00459,O00754,P16278,O75844,Q96PU5,P10644 16 +Abnormality of corneal stroma 0.874026352938968 2.839185915023622 0.0045228796615717 0.9999999991601266 0.2290535679525762 14 P34913,Q13510,P04062,P01130,P10619,P16278 6 +Ascites 0.7764340754035023 2.8242731878002645 0.0047387974788568 0.9999999996910316 0.2290535679525762 24 Q14108,Q13510,P04062,O15118,P61916,Q14739,P38571 7 +Juvenile onset 0.6563490678693347 2.806571826108196 0.0050071748193911 0.999999999910882 0.2290535679525762 43 O14773,Q13510,P22466,O15118,P54802,P06280,P16278 7 +Abnormal conjunctiva morphology 0.7476410995824414 2.804125421491902 0.0050453274470405 0.9999999999253216 0.2290535679525762 27 P01889,P04066,Q13510,Q14739,P06280,P10619,P02786 7 +Abnormal circulating cholesterol concentration 0.7027988258111348 2.789864568171389 0.0052730093509005 0.999999999973999 0.2290535679525762 35 P34913,P01130,P61916,Q9UBM7,Q15904,P38571,Q15392,P07602 8 +Abnormal atrioventricular valve physiology 0.6310018216915203 2.7809204726267054 0.0054205014052988 0.9999999999868748 0.2290535679525762 54 P01889,P19022,P04062,P01130,Q96PY6,P06280,O00170,P49459,Q15904,O00459,O00754,O75844,P10644 13 +Abnormality of head blood vessel 0.7596014691097424 2.7780734907284823 0.0054682249040183 0.9999999999894794 0.2290535679525762 25 Q13510,P01130,P10619,P16278,P17900,P07602,P06865 7 +Cherry red spot of the macula 0.9637009039452012 2.764199849528755 0.005706257826253 0.9999999999965102 0.2290535679525762 9 Q13510,P10619,P16278,P17900,P07602,P06865 6 +Coarse facial features 0.6111073584302611 2.7609943906011556 0.0057625666141214 0.9999999999973122 0.2290535679525762 63 P04066,P15586,Q7LGA3,P54802,P06280,P10619,O00170,P07686,O00754,P16278,O95831 11 +Abnormal tissue metabolite concentration 0.8340029236713901 2.7577481400131014 0.0058201021404249 0.9999999999979416 0.2290535679525762 16 P17900,P07602,P06865,P06280 4 +Abnormal circulating lipid concentration 0.5603685417590449 2.74301995604357 0.0060876985703566 0.9999999999994048 0.2290535679525762 82 P34913,P01130,P28070,P61916,Q14739,Q9UBM7,P06280,Q15056,Q15904,O43772,P38571,Q15392,O75844,P07602 14 +Hepatosplenomegaly 0.6713703740956781 2.7362942428022916 0.0062135439056267 0.999999999999668 0.2290535679525762 39 Q13510,P51798,P04062,Q14739,P10619,Q9Y3Z3,P07686,O00754,P16278,P38571,P11166 11 +Skin nodule 0.7764478155599764 2.711026936326786 0.0067075177031363 0.9999999999999664 0.2324936587327722 21 P01130,P34913,Q13510,P06280 4 +Abnormal urine carbohydrate level 0.8950432374244314 2.7045054813063447 0.0068406141114054 0.999999999999982 0.2353375451759641 11 P10253,P04066,O00754 3 +Abnormality of extrapyramidal motor function 0.5599607395339085 2.6887126554039993 0.0071728132645214 0.999999999999996 0.2397375620286079 80 Q99720,P04062,P06753,P02792,Q06787,Q15056,P05067,P07686,P16278,P49768,P17900,P07602,Q15043,Q9NUM4,P06865,P11166 16 +Abnormality of the gingiva 0.6278835349054624 2.683707044001135 0.0072810876163755 0.9999999999999976 0.2397375620286079 47 Q14108,P04062,Q14739,Q9UBM7,O00754,P16278,Q15392,P53634,P10644 9 +Ectopic calcification 0.6083615183534472 2.6660176663551054 0.0076755659385012 0.9999999999999996 0.2440300619068335 58 P04062,P01130,O00584,Q14739,Q9UBM7,P05067,P38571,O75844,P53634,P10644,P11166 11 +Abnormal retinal artery morphology 0.7601538089846412 2.663209683305427 0.0077399167382514 0.9999999999999996 0.2443905216667075 22 Q13510,Q96PY6,P10619,P07686,P16278,P17900,P07602,P06865 8 +Arthritis 0.6524956173126661 2.6527360732962344 0.0079842273699901 1.0 0.2474997543300085 40 Q14108,P01889,Q13510,P04062,Q14739,P06280,O00170,O75844,P10321 9 +Abnormal vascular physiology 0.6106799906600675 2.6327597473431346 0.008469423418425 1.0 0.2535327399931135 54 Q14108,P01889,Q8IZA0,P04062,O96000,Q14739,P06280,P11047,Q15056,P49459,Q9Y6K9,P05067,O75844 13 +Supranuclear gaze palsy 0.7633861891956637 2.612484129336063 0.0089886865619819 1.0 0.2578579589797505 20 Q99720,O15118,P61916,P02792,P07602 5 +Dysostosis multiplex 0.977798252333657 2.605006307008016 0.00918725687576 1.0 0.2582515499832551 7 P04066,P15586,P54802,P10619,O00754 5 +Exaggerated startle response 0.9468481409632828 2.5929541455648737 0.0095155456608098 1.0 0.2658585787656559 8 P17900,P16278,P06865 3 +Abnormal aortic valve physiology 0.6412058416494252 2.5782371597774043 0.009930581599419 1.0 0.2708874625640348 40 P01889,P04062,P01130,O00754,P16278,O75844,Q96PU5 7 +Limb ataxia 0.7128666848651458 2.5675787265342502 0.0102411531519748 1.0 0.276091906611719 26 Q14108,O14773,P04062,Q9H173,Q8IV08,Q10713,O00754 7 +Abnormal autonomic nervous system physiology 0.6909165573727383 2.554912108179649 0.0106214614019031 1.0 0.2823931773650756 29 P42892,P07602,P07686,P06280 4 +Macroglossia 0.6640464513372136 2.5520879015121203 0.0107079499595026 1.0 0.2823931773650756 35 P04066,Q7LGA3,O00170,P10253,Q10713,P07686,O00754,P16278 8 +Chronic diarrhea 0.7676457864146854 2.548084452986917 0.0108316245649147 1.0 0.2823931773650756 18 P02786,Q15904,Q13510 3 +Abnormality of glycolipid metabolism 0.9623135491587368 2.547947372956948 0.0108358816344493 1.0 0.2823931773650756 7 P17900,P07602,P06865,P06280 4 +Abnormal cerebral artery morphology 0.784562454615744 2.5285045212595003 0.0114549611055425 1.0 0.2823931773650756 16 P01130,P05067 2 +Progressive neurologic deterioration 0.7525203812055935 2.527856917131443 0.01147611109619 1.0 0.2823931773650756 19 P04062,P54802,P07686,P16278,P07602 5 +Foam cells 0.9726205865865768 2.514918621745887 0.0119059861954755 1.0 0.2823931773650756 6 Q13510,P61916,P16278,O15118 4 +Clumsiness 0.7379102777852268 2.514738783320672 0.0119120606109297 1.0 0.2823931773650756 21 P07602,O75503,O14773,O00754 4 +Abnormal oral mucosa morphology 0.5830093503985516 2.514231002651602 0.0119292267908863 1.0 0.2823931773650756 61 Q14108,P01889,P04062,Q14739,Q9UBM7,O00754,P16278,Q15392,P53634,P10644 10 +Abnormal retinal vascular morphology 0.5957207240241541 2.4902986923679755 0.0127635778408408 1.0 0.2927367853048565 51 Q13510,P10619,P07686,P16278,P17900,P07602,P06865 7 +Abnormal mitral valve physiology 0.6152566760622636 2.482772112011274 0.0130364457447016 1.0 0.2975149251637355 42 P01889,P04062,P01130,P06280,O00170,P49459,O00459,O00754,O75844 9 +Macular degeneration 0.8079230178549427 2.472194242787748 0.0134286530115981 1.0 0.3025934719581734 13 P04439,Q13510,P50897 3 +Arthralgia 0.646312969345435 2.471469791582156 0.0134558919200489 1.0 0.3025934719581734 36 P01889,Q13510,P01130,P28070,P02792,P06280,O00170 7 +Abnormal macrophage morphology 0.9581175630807642 2.461805932394218 0.0138239444269145 1.0 0.3093610864469722 6 Q13510,P61916,P16278,O15118 4 +Hypotension 0.6917486355244304 2.4497486227592984 0.014295597861043 1.0 0.3167408986894589 26 P04062,Q13423,O43772,P07686,P07602 5 +Abnormal systemic arterial morphology 0.5571768501099769 2.4478413414025355 0.0143714924284539 1.0 0.3167408986894589 145 P01130,Q7LGA3,P61916,Q9UBM7,P05067,P07602,P06865,P10619,P10253,P16278,P17900,P34913,P19022,Q13510,O15118,P07686,O00459,P38571,Q96PU5,P10644,P01889,P04062,Q96PY6,Q15056,O75844 25 +Retinal degeneration 0.5856485389850656 2.446651910735191 0.0144190019886398 1.0 0.3167408986894589 54 O14773,Q13510,P04062,O75503,O00754,P50897,P04439 7 +Abnormal tongue morphology 0.5445443057342316 2.442658999807828 0.0145795057865505 1.0 0.3176743153114924 75 P01889,O43924,P04066,Q7LGA3,Q9UBM7,Q96PY6,Q15056,O00170,P10253,Q10713,P07686,O00754,P16278,O75844 14 +Cerebral inclusion bodies 0.7850336581769436 2.4419323491939684 0.0146088839145415 1.0 0.3176743153114924 14 P61916,P05067,O15118 3 +Hypersplenism 0.906462083676464 2.438612515118055 0.0147437680608788 1.0 0.3179037496548311 8 Q14108,P07602,P38571 3 +Hallucinations 0.5923173194930171 2.4377331313163313 0.0147796806133586 1.0 0.3179037496548311 48 Q9BQE5,P04062,O75503,P05067,O00754,P50897,P07602 7 +Abnormal form of the vertebral bodies 0.5126333974027726 2.4363722327937496 0.0148354093861038 1.0 0.3179037496548311 88 P04066,Q15643,P51798,P15586,P54802,Q14739,Q9UBM7,Q96PY6,Q15056,O00170,Q10713,Q9Y6K9,O00754,P16278,Q32P28,O95831,P10644 17 +Urinary glycosaminoglycan excretion 0.9508098158825382 2.4349153633419105 0.0148952733026992 1.0 0.3179037496548311 6 P15586,P54802,P04066 3 +Psychomotor deterioration 0.8786098369343602 2.4327254623031433 0.0149856584870677 1.0 0.3183589199326382 9 P07602,P50897 2 +Abnormal rib cage morphology 0.5353848978908177 2.42746979542396 0.0152045528449047 1.0 0.3215274707110589 78 P04066,Q15643,P15586,P54802,Q14739,Q9UBM7,Q96PY6,Q9Y6K9,O00754,P16278,O75844,Q32P28,O95831 13 +Increased cerebral lipofuscin 0.9808279631512088 2.425790845983656 0.0152750706624122 1.0 0.3215437249028341 5 O75503,O14773,P50897 3 +Periventricular white matter hyperintensities 0.9004609478613816 2.415425606270306 0.0157168327439225 1.0 0.3222304569211935 8 P07602,O75503 2 +Mucosal telangiectasiae 0.8472811592835195 2.4037545784110868 0.0162276635931302 1.0 0.3295573971996929 10 P10619,Q8IZA0,P06280 3 +Parkinsonism 0.6395353345999457 2.3980510375886284 0.0164825684629998 1.0 0.3332659676071469 35 Q99720,P04062,P02792,Q06787,P05067,P49768,P07602,Q9NUM4,Q15043 9 +Follicular hyperkeratosis 0.8950518215512999 2.394469790359883 0.0166444145174582 1.0 0.3350687813339846 8 Q14574,Q07954 2 +Oligosacchariduria 0.971153570245176 2.3905580320480233 0.0168227903065765 1.0 0.3371872317970337 5 P10253,P04066,O00754 3 +Hyperkeratosis 0.5639204794160938 2.3785238237627753 0.0173821136674316 1.0 0.3441239944155179 62 Q02487,P04066,P04062,Q07954,P06280,Q14574,O75844,P53634 8 +Sepsis 0.7008294793139069 2.3524602667402315 0.0186496821212309 1.0 0.3538067266620361 22 P02786,P42892 2 +Cupped ear 0.7807207522475548 2.350492270082988 0.0187485970758705 1.0 0.354225543113783 13 P42892,P78318,Q15392 3 +Increased circulating antibody level 0.7633030790343392 2.341818635235888 0.019190037596237 1.0 0.3610860135455216 14 Q14108,P04062,P28070,Q9Y6K9,P13051 5 +Pulmonary infiltrates 0.9208875349461044 2.323911446692542 0.0201302406394749 1.0 0.3726924070199989 6 P01889,Q13510 2 +Abnormal morphology of the conjunctival vasculature 0.9007202097429808 2.3169743200529163 0.0205051306921921 1.0 0.3766081772550037 7 P04066,P06280 2 +Progressive psychomotor deterioration 0.8737350946923693 2.311364997130854 0.0208127026450597 1.0 0.3807403142608151 8 P07602,P07686,P16278 3 +Increased bone mineral density 0.6803457259372939 2.30910028437794 0.0209380169921165 1.0 0.3814694043356081 24 Q14108,P04062,P54802,Q14739,Q15056,Q15392,Q15043 7 +Abnormal arterial physiology 0.6489472195447575 2.307660010007206 0.0210180539482092 1.0 0.3814694043356081 29 P01889,Q14739,P06280,Q15056,Q9Y6K9,P05067,O75844 7 +Abnormal pulmonary interstitial morphology 0.6440804583472634 2.299411770590181 0.0214815681885414 1.0 0.388353056271278 30 Q14108,Q8IZA0,Q13510 3 +Abnormal exteroceptive sensation 0.5632416751398189 2.297883020284324 0.021568447942768 1.0 0.3884005664693772 56 P01889,P54802,P06280,O00170,P05067,P07686,P07602,O95831 8 +Tissue ischemia 0.6818375151308507 2.2827309184454374 0.0224462233750191 1.0 0.4021455504293668 23 P01889,P06280,Q15056,P05067,O75844 5 +Acute coronary syndrome 0.7033557168294634 2.2779998191449535 0.0227265883738789 1.0 0.4036427465734812 19 P01130,P01889,O75844,P06280 4 +Ovoid vertebral bodies 0.8650720033686042 2.2773538996322107 0.0227651006744262 1.0 0.4036427465734812 8 P15586,P54802 2 +Osteolysis 0.6426787038202962 2.270080985821925 0.0232026697682932 1.0 0.4067083940373829 29 Q14108,P04062,Q9Y6K9,O00754,O75844,P53634 6 +Dermal atrophy 0.6348851968213645 2.2654554892671652 0.0234847425018966 1.0 0.4084675191280667 31 Q07954,O00170,O75844,Q15392,P53634 5 +Abnormal coronary artery morphology 0.8863306499098127 2.262085993364072 0.0236920908131974 1.0 0.4084675191280667 7 P01130,P16278 2 +Abnormal vertebral morphology 0.5141084689354061 2.2595580190720024 0.0238486955852772 1.0 0.4084675191280667 112 P15586,Q9UBM7,O00170,Q9Y6K9,Q14108,P04066,Q15643,P51798,P54802,Q14739,P10619,O00754,P16278,Q10713,Q32P28,O95831,P10644,P04062,Q96PY6,Q15056 20 +Paresthesia 0.6582313929850495 2.2591438959361207 0.0238744353911777 1.0 0.4084675191280667 26 P01889,P54802,P06280,O00170,P05067 5 +Glomerulopathy 0.8115942558155314 2.255421583716382 0.0241068792309577 1.0 0.4084675191280667 10 Q14108,P06280 2 +Retinal dysplasia 0.8339015968169438 2.2529190867976747 0.0242642511699926 1.0 0.4084675191280667 9 O43924,O43505,Q10713,Q14118 4 +Abnormality of the tongue 0.5025812406564867 2.250130360191483 0.0244406713494098 1.0 0.4084675191280667 99 P01889,O43924,P04066,Q13510,Q7LGA3,Q9UBM7,Q96PY6,Q15056,O00170,P10253,Q10713,P07686,O00754,P16278,O75844,P67870,O95831 17 +Cardiomegaly 0.6163761056672579 2.2498332396934124 0.0244595331243888 1.0 0.4084675191280667 35 P04066,Q8NBF2,P04062,P54802,P13473,Q14739,Q15056,P10253,P07686,P10644 10 +Facial hypotonia 0.8095531859042887 2.2468568384811825 0.0246491778847057 1.0 0.4084675191280667 10 P10253 1 +Unusual infection by anatomical site 0.742908218983045 2.246720745928615 0.0246578795454706 1.0 0.4084675191280667 14 P02786,P01889,Q14739 3 +Platyspondyly 0.61998055265011 2.245739440108836 0.0247207023507007 1.0 0.4084675191280667 34 Q15643,P04066,Q14739,Q96PY6,O00754,P16278,Q32P28,O95831 8 +Orthostatic hypotension 0.7566838417813626 2.2414111740824008 0.0249994533761794 1.0 0.4115981430863836 13 P07602,P07686 2 +Hyperintensity of cerebral white matter on mri 0.6853399046449081 2.2389487520728935 0.0251592508508882 1.0 0.4127549694754259 21 P17900,P07602,O75503,P10253 4 +Abnormal urine cytology 0.5958828356392054 2.2374035379754185 0.0252599775170179 1.0 0.4129379303313922 39 Q14108,P01889,Q6YHK3,P06280 4 +Progressive spastic quadriplegia 0.8541360385331941 2.2342237553788884 0.0254683541355156 1.0 0.4148731892746538 8 P07602 1 +Abnormal midbrain morphology 0.7689716368308324 2.2316426257267397 0.0256385920352275 1.0 0.414976101059732 12 O43924,P04062,P02792 3 +Abnormality of the ribs 0.5384913579366413 2.230981369961982 0.0256823630924558 1.0 0.414976101059732 66 Q15643,P15586,P54802,Q14739,Q9UBM7,Q96PY6,Q9Y6K9,O00754,P16278,Q32P28,O75844,O95831 12 +Thickened ribs 0.9848394768133172 2.230040997936621 0.0257447212371113 1.0 0.414976101059732 4 P15586,P54802,O00754 3 +Abnormal heart sound 0.8954877146947806 2.228554014204934 0.0258435936572745 1.0 0.415118351080263 6 P01130,P10253 2 +Delusions 0.6881484196179155 2.2255087061699412 0.026047107326595 1.0 0.4156484720238009 20 P07602,P04062,O00754 3 +Elevated pulmonary artery pressure 0.6445806104128425 2.2197756326888136 0.0264340018036595 1.0 0.4156484720238009 27 Q14108,P01889,Q8IZA0,P04062,O96000,P11047,P49459,Q9Y6K9,O75844 9 +Blindness 0.4969687545961041 2.2187707016656866 0.0265023282091099 1.0 0.4156484720238009 84 Q6YHK3,P01889,P51798,O96000,O43505,P11047,O00170,P07686,O00459,P16278,P50897,P17900,P07602,P06865 14 +Prolonged neonatal jaundice 0.7015703551298578 2.2184930190692262 0.0265212350482542 1.0 0.4156484720238009 18 P61916,O15118 2 +Infantile axial hypotonia 0.8022288585224563 2.2160502911415096 0.0266880580735455 1.0 0.4156484720238009 10 P17900,P07602,O00754 3 +Avascular necrosis 0.6678142432606092 2.20567669971884 0.0274066444755092 1.0 0.4254027980878704 23 Q14108,P01889,P04062,O00754,O75844 5 +Skeletal muscle hypertrophy 0.5616579904279339 2.1969374111018385 0.0280249165316659 1.0 0.4273159556600014 46 P04066,Q7LGA3,Q15056,O00170,P10253,Q10713,P07686,O00754,P16278 9 +Increased blood pressure 0.518083896536435 2.1934270172802943 0.0282766275410843 1.0 0.4273159556600014 74 P42892,P01889,P04062,O94898,P01130,P06280,O00170,Q10713,P38571,O75844,P10644 11 +Abnormality of femur morphology 0.5241617281568209 2.1916506116998655 0.0284047444484996 1.0 0.4273159556600014 71 P04066,Q15643,Q9BXW9,P04062,Q7LGA3,Q9H173,Q9ULC3,Q14739,P06280,O00754,P16278,Q32P28,O75844,P07602,O95831 15 +Ventricular arrhythmia 0.5790713883909324 2.191616166975921 0.0284072335854037 1.0 0.4273159556600014 41 Q14126,P42892,Q02487,P13473,P10253,O43772 6 +Neuronal loss in central nervous system 0.7229238911179765 2.1912695309750956 0.0284322935873373 1.0 0.4273159556600014 15 P07602,O15118 2 +Abnormality of lipoprotein cholesterol concentration 0.7228863607825493 2.1910889615707654 0.0284453553701413 1.0 0.4273159556600014 15 P01130,P34913 2 +Multifactorial inheritance 0.7308655741569875 2.190048177012604 0.0285207430286227 1.0 0.4273159556600014 14 P42892,P10321,P01889 3 +Cataplexy 0.9709764831667572 2.179882637740831 0.0292661622387013 1.0 0.4338286625282764 4 P61916 1 +Bilateral talipes equinovarus 0.913805973160404 2.178854599523664 0.0293424713729533 1.0 0.4338286625282764 5 O00754,Q15392 2 +Eyelid myoclonus 0.7931767044695983 2.177820562854453 0.0294193983808821 1.0 0.4338286625282764 10 Q01105,Q13510 2 +Abnormality of the alveolar ridges 0.8642648771624795 2.177236267676719 0.0294629436034521 1.0 0.4338286625282764 7 P53634,O43924,Q15392 3 +Perseveration 0.8150470523179272 2.175910717881655 0.0295619372258935 1.0 0.4338286625282764 9 P61916,Q9NUM4 2 +Barrel shaped chest 0.9127263777874172 2.1748229021355323 0.0296433901727564 1.0 0.4338286625282764 5 Q15643,Q14739,P04066 3 +Undetectable electroretinogram 0.911964881274022 2.1719781154508655 0.0298573136529496 1.0 0.4355766327218285 5 O14773,P50897 2 +Arterial stenosis 0.7265777098036547 2.1697762872145496 0.0300237975843149 1.0 0.4357448362791902 14 P01130,P34913,P01889 3 +Abnormal ldl cholesterol concentration 0.7244111897707657 2.159514939223972 0.0308102395999509 1.0 0.4418133034898581 14 P01130,P34913 2 +Abnormal large intestine physiology 0.6740700555963317 2.1510052912584774 0.0314757820463384 1.0 0.4418133034898581 20 P07602,P06280 2 +Disproportionate short stature 0.6395389946069838 2.1508957899815884 0.0314844259193305 1.0 0.4418133034898581 26 Q15643,Q7LGA3,Q14739,Q9UBM7,Q32P28,P16278,Q15392 7 +Abnormal endocardium morphology 0.7060723463687048 2.150446569328244 0.0315199080644723 1.0 0.4418133034898581 16 P01889,P04062,P10644,P06280 4 +Cirrhosis 0.5877259803257981 2.1492584127770997 0.0316139211764865 1.0 0.4418133034898581 38 Q14108,P04062,Q14739,Q15904,P11717,P38571 6 +Abnormal biliary tract morphology 0.6574903019819938 2.148488560706741 0.0316749641735434 1.0 0.4418133034898581 23 Q14108,P07602,P04062,Q14739 4 +Visual loss 0.5475252834594827 2.1457907401096024 0.0318896777511543 1.0 0.4418133034898581 53 P01889,O14773,O75503,O00170,Q10713,Q92734,P50897,P04439,P07602 9 +Heterogeneous 0.5559334058398403 2.1419258725043595 0.0321994475299116 1.0 0.4418253091915597 44 Q14126,P01889,Q9BQE5,P51798,P61916,Q9Y619,P05067,P11717,O75844,P49768,P06753,P53634,P29372 13 +Neurofibrillary tangles 0.9023332457715358 2.1359242500385323 0.0326855886374555 1.0 0.4418253091915597 5 P61916,P05067 2 +Hyperlipoproteinemia 0.7607557978238954 2.134581204582231 0.0327952340737027 1.0 0.4418253091915597 11 P01130,P34913 2 +Increased ldl cholesterol concentration 0.7607557978238954 2.134581204582231 0.0327952340737027 1.0 0.4418253091915597 11 P01130,P34913 2 +Recurrent skin infections 0.6707596742741957 2.1333895419879907 0.0328927842446986 1.0 0.4418253091915597 20 P02786,P49459,P78536,P53634 4 +Abnormality of pulmonary circulation 0.6135306334265614 2.1331570743606 0.0329118431055497 1.0 0.4418253091915597 31 Q14108,P01889,Q8IZA0,P04062,O96000,P11047,P49459,Q9Y6K9,O75844 9 +Abnormal lower motor neuron morphology 0.7822142379920216 2.1312929232166207 0.0330650177160711 1.0 0.4418253091915597 10 P49768,Q99720,Q13510,Q9NUM4 4 +Angina pectoris 0.9004539396274157 2.128873962522007 0.0332646895193069 1.0 0.4432050382741717 5 P01130,P06280 2 +Cognitive impairment 0.5405860320245424 2.126287657443688 0.0334793151170278 1.0 0.4432050382741717 174 Q9BQE5,O75503,P61916,P06280,P05067,P50897,P07602,P06865,Q14108,P54802,P13473,P16278,P17900,Q13510,O15118,P02792,Q10713,P07686,Q99720,Q9NUM4,O95831,P11166,P10644,P01889,P04062 25 +Coxa valga 0.653343036007746 2.1254050098599055 0.03355283261555 1.0 0.4432050382741717 23 Q15643,P04066,Q9H173,O00754,P16278,O75844 6 +Aortic valve stenosis 0.7798109490853202 2.1210591189127603 0.0339168276683166 1.0 0.4458736812753389 10 P04062,P16278 2 +Recurrent bacterial infections 0.6523642015054805 2.1199476183535944 0.0340104630007604 1.0 0.4458736812753389 23 P78536,Q15904,P49459,Q9Y6K9,O00754,P53634,P13051 7 +Diplopia 0.6572741505960061 2.116473340145927 0.0343045702841366 1.0 0.4458736812753389 22 O00170,O14773,P04062,P01889 4 +Atrophic scars 0.8244364421315441 2.115994026458201 0.0343453156227375 1.0 0.4458736812753389 8 Q07954 1 +Delayed fine motor development 0.7777785475028535 2.112395236222155 0.0346525632643515 1.0 0.4458736812753389 10 O94992,Q5KU26,P19022 3 +Fasciculations 0.5726883669420164 2.111296200159751 0.0347468604571601 1.0 0.4458736812753389 40 Q13510,Q9H0U9,Q14203,P06280,P07686,Q9NUM4,Q92734,P49768,Q8TD16,P07602,O95831 11 +Abnormality of the upper respiratory tract 0.4896856489896035 2.109078092439889 0.0349378415040038 1.0 0.4461591394278602 101 P01889,P04066,Q13510,P15586,P54802,P28070,Q14739,Q9UBM7,Q96PY6,O00754,P16278,P07602,P10644 13 +Decerebrate rigidity 0.9505829784621154 2.105654253710218 0.0352343962584102 1.0 0.4487032230698106 4 P07602 1 +Meningitis 0.8616927542788484 2.100085133352111 0.0357213528531115 1.0 0.4523647282099193 6 P02786 1 +Emg neuropathic changes 0.6540869107166921 2.098939215379093 0.0358222593653312 1.0 0.4523647282099193 22 P07602,O14773 2 +Abnormality of skull ossification 0.7114561114139084 2.0978949852639284 0.0359144231073385 1.0 0.4523647282099193 14 P54802,Q15643,Q14739,O75844 4 +Oculomotor apraxia 0.6125772034679404 2.0872306906228046 0.0368672864856622 1.0 0.4597530111747927 29 P28482,O43924,O14773,O00429,P04062,Q9Y3C8,Q99700,O43292,Q10713,P05067,P18887,P11274,P49768,Q69YN2,Q9UNE7 15 +Increased circulating lactate dehydrogenase concentration 0.7226199451775437 2.084340518302608 0.0371292042100226 1.0 0.4612408955589266 13 P10253 1 +Abnormal visual fixation 0.8388757898387255 2.0785965330047587 0.0376544499179145 1.0 0.4653807349104185 7 Q5KU26,Q13510,P04062 3 +Pedal edema 0.8381482497931728 2.075754173929312 0.037916692689897 1.0 0.4657960907207134 7 Q14108,P04062 2 +Subcutaneous nodule 0.6819627031457227 2.072774629132652 0.0381932586317634 1.0 0.4657960907207134 17 Q13510,P06280 2 +Confusion 0.6636170709301535 2.0702985453960467 0.0384243957279559 1.0 0.4673785337885937 19 P01889,P05067,O00754,P49768,P11166 5 +Abdominal pain 0.4884818966588918 2.069014210114852 0.0385447532525209 1.0 0.4676087170897934 81 Q14108,P42892,P01889,P04062,Q13423,P06280,P07686,P10644 8 +Middle age onset 0.7454623929519248 2.0671126755195814 0.0387235379831931 1.0 0.4685446459383741 11 P07602,P02792 2 +Inappropriate behavior 0.6718607491834248 2.0658609251628564 0.0388416133531561 1.0 0.4687430302566752 18 P17900,P07602 2 +Postaxial hand polydactyly 0.6796190575899197 2.0608729775082306 0.0393151599176111 1.0 0.4714183814951187 17 O43924,Q96J42,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q10713,O00459 8 +Cheilitis 0.8511683914774151 2.0597115786799263 0.0394261218441374 1.0 0.4714183814951187 6 Q14574 1 +Hypohidrosis 0.7864777011732942 2.05789726630151 0.039599996224505 1.0 0.4714183814951187 9 P07686,P06280 2 +Cardiac arrest 0.58675499982042 2.0563890465507733 0.0397450312447087 1.0 0.4714183814951187 35 P01889,Q02487,P04062,P01130,O43772 5 +Focal non motor seizure 0.7429746295376394 2.0560883507256107 0.0397740009046323 1.0 0.4714183814951187 11 Q01105,P22466 2 +Hydrops fetalis 0.5497339730051354 2.056035219264533 0.0397791215621694 1.0 0.4714183814951187 43 Q15643,Q13510,P04062,Q14739,Q96PY6,P10619,P16278 7 +Aplasia hypoplasia involving the vertebral column 0.6942374543861816 2.052113588295749 0.040158624672177 1.0 0.4738198049887245 15 O95831,P04066,Q14739,P16278 4 +Abdominal distention 0.640197355440876 2.0518183458510775 0.0401873196855946 1.0 0.4738198049887245 23 P07602,P04062,P38571 3 +Recurrent bacterial skin infections 0.87962638717506 2.05040349707324 0.0403250722194363 1.0 0.4742310789071471 5 P49459,P78536,P53634 3 +Abnormality of skin adnexa physiology 0.5587345092994487 2.047284641388532 0.0406301450019128 1.0 0.4744133519076561 41 P01889,P04066,P04080,P06280,O00170,P07686 6 +Emg chronic denervation signs 0.7280004273526385 2.047089474737256 0.0406493002176842 1.0 0.4744133519076561 12 P07602 1 +Vertebral compression fracture 0.6672650809534124 2.042003513850758 0.0411511827770174 1.0 0.4776139325429894 18 Q14108,O00170,P04062 3 +Abnormality of humoral immunity 0.5264836487376026 2.040548164794768 0.0412957589406404 1.0 0.4776139325429894 59 Q14108,P04062,P28070,Q15904,Q9Y6K9,O00754,P02786,P13051 8 +Tachycardia 0.6266927229025053 2.0399347651673265 0.0413568235652697 1.0 0.4776139325429894 25 Q14126,P42892,O43772 3 +Osteoarthritis 0.7387812178116809 2.0374745204244524 0.0416025127464827 1.0 0.4776139325429894 11 Q14108,P01889,P04062,O75844 4 +Cachexia 0.665616682447996 2.0334301065760343 0.0420090882452477 1.0 0.4805506124332309 18 P07602,Q99720,P38571 3 +Eeg with spike wave complexes 0.681017845177651 2.0260406737182315 0.0427606167469214 1.0 0.4855184609382583 16 Q14108,O75503,P11166 3 +Abnormal lactate dehydrogenase level 0.6640311900640751 2.02517586297021 0.0428493092184671 1.0 0.4855184609382583 18 Q9H173,P10253,O43505,P38571 4 +Abnormality of the 5th toe 0.7230873802458837 2.0246929140981873 0.0428989066888247 1.0 0.4855184609382583 12 O43924,Q96J42,Q14739,Q9UBM7,Q96PY6,Q10713 6 +Postaxial foot polydactyly 0.7230873802458837 2.0246929140981873 0.0428989066888247 1.0 0.4855184609382583 12 O43924,Q96J42,Q14739,Q9UBM7,Q96PY6,Q10713 6 +Biliary tract abnormality 0.6177574952657867 2.022979296347671 0.0430752821092728 1.0 0.4855184609382583 26 Q14108,P07602,P04062,Q14739 4 +Macrogyria 0.8396699580689652 2.0154062178163783 0.0438621034774142 1.0 0.4928688820561006 6 O43505,Q15392 2 +Bone pain 0.6436429070539055 2.0134350208421505 0.0440688844573118 1.0 0.4928688820561006 21 Q14108,P04062,P51798,P07602,P10644 5 +Abnormality of the autonomic nervous system 0.5326602077214266 2.0133778708273455 0.044074891818242 1.0 0.4928688820561006 51 P42892,P04062,Q9BXW9,Q9H0U9,Q9UBM7,P06280,Q10713,P07686,P07602 9 +Abnormal leukocyte physiology 0.5140576977017874 2.0126157883546303 0.044155064704809 1.0 0.4928688820561006 65 Q14108,P04062,P28070,Q15904,Q9Y6K9,O00754,P02786,P13051 8 +Visual fixation instability 0.9246218880012038 2.0104224371465467 0.0443864977413512 1.0 0.4942554458638392 4 Q5KU26,Q13510 2 +Sparse body hair 0.7190844070317867 2.0064033217217956 0.0448132342111169 1.0 0.4966580183073402 12 Q02487,Q9BZH6,P04080,Q14574,P53634 5 +Thickened skin 0.484926565317816 2.0063611507300245 0.0448177300685148 1.0 0.4966580183073402 108 Q14126,Q02487,P04066,P04062,Q07954,P28070,Q15126,Q14739,P06280,Q14574,O00170,P16278,O75844,P53634 14 +Endocarditis 0.8367508436960451 2.0041263109398892 0.0450565316223214 1.0 0.4969153367916316 6 P01889,P04062 2 +Recurrent respiratory infections 0.502221123767551 1.99953509896782 0.0455504881523605 1.0 0.4984286269153769 132 P01889,P04066,P53634,Q13510,P04062,Q15643,P15586,P54802,P78318,P51798,P11047,Q15056,P10253,P49459,P16278,P02786,P07602,P13051 18 +Flared iliac wing 0.818671586201981 1.9993404799002277 0.0455715271356433 1.0 0.4984286269153769 7 Q15643,O95831,P16278 3 +Dyspareunia 0.9210083446652366 1.9971034710609756 0.0458139439584055 1.0 0.4984286269153769 4 O00170,P01889 2 +Joint swelling 0.8178814893715252 1.9962276556110723 0.0459091484814861 1.0 0.4984286269153769 7 Q13510 1 +Abnormal femoral neck head morphology 0.5338646369572752 1.994307755922345 0.0461184321745362 1.0 0.4984286269153769 47 Q15643,P04066,Q9H173,Q7LGA3,Q14739,O00754,P16278,O75844,O95831 9 +Gait ataxia 0.4965767645474134 1.9853395739155544 0.0471067039296486 1.0 0.5049652442043571 73 Q14108,O14773,O15118,Q9H173,Q8IV08,O00754,P07602,Q9NUM4 8 +Abnormality of lysosomal metabolism 0.8624639668186908 1.9852887151911327 0.0471123588396857 1.0 0.5049652442043571 5 P07602,Q13510 2 +Anarthria 0.8148836470570152 1.9844076263358972 0.0472104165405808 1.0 0.5049652442043571 7 P02792 1 +Mesomelia 0.7913366053757638 1.982361759048232 0.0474387663761448 1.0 0.5051851475379463 8 Q15643,Q14739,Q9UBM7 3 +Scarring 0.5892675822405434 1.980304581096014 0.0476693143555329 1.0 0.5051851475379463 31 Q92542,P53634,Q07954 3 +Corpus callosum atrophy 0.6713922272756759 1.9777669724860585 0.0479550009971263 1.0 0.5053157805829996 16 O75503 1 +Abnormal circulating copper concentration 0.8298564124861049 1.9774341348907136 0.0479925787183885 1.0 0.5053157805829996 6 Q8NB90,Q15904 2 +Abnormality of ocular smooth pursuit 0.6269951054814897 1.97727565639858 0.0480104798037643 1.0 0.5053157805829996 23 O14773,Q06787,P02792,Q10713,O00754 5 +Abducens palsy 0.9145426862306644 1.9732343134932624 0.0484688727659201 1.0 0.5066700758523627 4 P07602 1 +Hyperkalemia 0.826773539746573 1.9654755810774085 0.0493592192225751 1.0 0.512243560231278 6 Q13423,P11166 2 +Coronary artery atherosclerosis 0.8570647357873182 1.9647212921865929 0.0494465041871841 1.0 0.512243560231278 5 P01130 1 +Aspiration 0.7216247134737108 1.9609164981017513 0.0498887644383336 1.0 0.515666376817754 11 P06865 1 +Abnormal substantia nigra morphology 0.8557647097916297 1.959763263849551 0.050023466885074 1.0 0.5156884436934803 5 P02792 1 +Abnormal anterior horn cell morphology 0.8247384816846971 1.9575737832878028 0.0502800461468257 1.0 0.5156884436934803 6 Q13510,Q92734 2 +Airway obstruction 0.6951435861968849 1.9555355119539115 0.050519896076469 1.0 0.5156884436934803 13 P06280 1 +Protuberant abdomen 0.8063413765505304 1.9506480245289617 0.0510989301660735 1.0 0.5156884436934803 7 P04062,P38571 2 +Abnormal epidermal morphology 0.62684959682879 1.9476193200760137 0.0514605302695714 1.0 0.5174503071520314 22 Q14574,Q02487,Q07954,P01889 4 +Skin vesicle 0.6933617623692241 1.9471184100400785 0.0515205403433367 1.0 0.5174503071520314 13 Q14574 1 +Esophageal varix 0.9053997370665186 1.9394001935142704 0.0524526269889 1.0 0.5227180357581741 4 P38571 1 +Bloody diarrhea 0.8026226582775848 1.9359152829347697 0.0528780776346691 1.0 0.5227180357581741 7 Q6YHK3 1 +Proportionate short stature 0.5645979851498562 1.9344380579001872 0.053059291000586 1.0 0.5227180357581741 36 Q15643,Q9H173,Q14739,P10619,P16278,Q15392 6 +Chronic fatigue 0.8019653699366496 1.9333089891497184 0.0531981451153205 1.0 0.5227180357581741 7 P07602 1 +Orthostatic hypotension due to autonomic dysfunction 0.7565822629393947 1.932721752340646 0.0532704840598492 1.0 0.5227180357581741 9 P07602 1 +Acne 0.6619211384666079 1.930011313511062 0.0536054359705313 1.0 0.5227180357581741 16 P01889,O00170,Q92542 3 +Abnormal pharynx morphology 0.5549445051782949 1.9238153519252408 0.0543777324312431 1.0 0.5255374140629575 38 P15586,P54802,Q13510,P16278 4 +Agnosia 0.7337180393985007 1.922475438427656 0.0545459612519239 1.0 0.526001854855782 10 Q9UQN3,P60866,P05067,P49768,Q9NUM4 5 +Abnormal aldolase level 0.9006042508142826 1.9216168338985768 0.0546539888234098 1.0 0.526001854855782 4 Q9H173,O43505 2 +Mutism 0.6512661788586976 1.915591305998153 0.0554171370552505 1.0 0.5303281894859767 17 Q13510,P02792 2 +Severe short stature 0.5993419070150405 1.9133346699630596 0.0557052220191069 1.0 0.5303281894859767 26 P10619,Q15643,P16278,Q15392 4 +Vascular calcification 0.812966626653979 1.9117459672233317 0.0559087852690205 1.0 0.5303281894859767 6 P01130 1 +Dilatation of the cerebral artery 0.7306579900851952 1.909138960425253 0.0562441679514627 1.0 0.5324139923126141 10 P10253 1 +Beaking of vertebral bodies 0.7940602915301062 1.9019107688320696 0.0571828211013412 1.0 0.5379853168922102 7 P04066 1 +Abnormal sella turcica morphology 0.7929068738985824 1.8973213997290432 0.0577855323029659 1.0 0.5380604710171819 7 O00754 1 +Abnormal saccadic eye movements 0.6018284568243757 1.894278454509114 0.0581880592783028 1.0 0.5380604710171819 25 Q8IV08,O14773,P04062,Q10713 4 +Transient ischemic attack 0.7472970515746247 1.8935011167730489 0.0582912598481786 1.0 0.5380604710171819 9 P06280 1 +Telangiectasia of the skin 0.6169762765054881 1.892116844514854 0.05847541447542 1.0 0.5380604710171819 22 Q8IZA0,Q14739,P06280 3 +Inflammatory abnormality of the eye 0.5325018516731644 1.8919047998363228 0.0585036661625388 1.0 0.5380604710171819 42 P01889,P04080,P28070,Q14739,Q9Y6K9,P02786,P04439 7 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9970291146761736 1.8904923952200277 0.058692136705956 1.0 0.5380604710171819 2 O14773 1 +Cutaneous abscess 0.8072991233294563 1.8896106077036317 0.0588100574227974 1.0 0.5380604710171819 6 P49459,P53634 2 +Abnormal ilium morphology 0.6295212311181457 1.8879712370887356 0.0590298119276735 1.0 0.5380604710171819 19 P01889,Q15643,O00754,P16278,O95831 5 +Anorexia 0.588976997561212 1.886455640763704 0.0592335806965107 1.0 0.5380604710171819 27 Q14108,P01889,P04062,Q13423,P06280 5 +Abnormal femoral neck morphology 0.5444120234673242 1.8796196875105031 0.0601599281536082 1.0 0.5437985662512433 39 Q15643,P04066,Q9H173,O00754,P16278,O75844,O95831 7 +Abnormality of secondary sexual hair 0.7231847202780718 1.8764905937303344 0.0605879451205706 1.0 0.5465957475652263 10 Q14574,Q02487 2 +Vertical supranuclear gaze palsy 0.6901239086217696 1.8729823616145005 0.0610708207021648 1.0 0.5498759442128516 12 P61916,O15118 2 +Enlarged thorax 0.6424988399488357 1.8701863563726095 0.061457943687587 1.0 0.5520182817337572 17 Q15643,P04066,Q14739,O75844 4 +Abnormal visual electrophysiology 0.5159927427428866 1.8690861977195332 0.0616108229610279 1.0 0.5520182817337572 49 P07602,O75503,O14773,P50897 4 +Ecchymosis 0.6638805396265053 1.8678159491018815 0.0617877295823467 1.0 0.5520182817337572 14 Q6YHK3,O00170,P04062 3 +Abnormal lymphocyte morphology 0.5650635056074641 1.865488746350888 0.0621129281599124 1.0 0.5538502878475751 33 P04066,O00754,P16278 3 +Eeg with polyspike wave complexes 0.762073775867969 1.8626310970767943 0.0625141860857967 1.0 0.5552801500106415 8 Q14108,P11166 2 +Abnormal epiglottis morphology 0.829976388284281 1.8609583406274937 0.0627500599669961 1.0 0.5558787310471521 5 Q13510 1 +Asymmetric septal hypertrophy 0.9878193701723116 1.8542067179373125 0.0637095913560514 1.0 0.5597665609045993 2 P15586 1 +Breast hypoplasia 0.8281527575569383 1.8539394805207192 0.0637478187581159 1.0 0.5597665609045993 5 Q9Y6K9,Q9BZH6 2 +Vascular skin abnormality 0.4793870273753934 1.851323978524245 0.0641229584634497 1.0 0.5606601520574425 121 Q14108,Q6YHK3,Q8IZA0,P01889,P04066,P04062,Q07954,Q9BXW9,P78536,Q14739,Q9UBM7,P06280,P10619,O00170,Q9Y6K9,P16278,O75844,P10644 18 +Temporal cortical atrophy 0.7809012362927785 1.8494310958478817 0.0643955887636877 1.0 0.5606601520574425 7 O43924,Q9NUM4,Q96PY6 3 +Angular cheilitis 0.8809569466814333 1.8484990875227625 0.0645301762612375 1.0 0.5606601520574425 4 Q14574 1 +Erlenmeyer flask deformity of the femurs 0.8807821211367286 1.8478466609804427 0.0646245285715072 1.0 0.5606601520574425 4 P07602,P04062 2 +Abnormal pulmonary thoracic imaging finding 0.6302244115542154 1.847319066170465 0.0647009112569543 1.0 0.5606601520574425 18 P01889,Q13510 2 +Diminished motivation 0.5879173631910268 1.8446298896300208 0.0650913959590053 1.0 0.5618916280249737 26 P04062,Q06787,P49768,P17900,Q9NUM4,P06865 6 +Chorioretinal dysplasia 0.7958150856340719 1.844617966100768 0.0650931316465701 1.0 0.5618916280249737 6 O43505 1 +Hypercholesterolemia 0.6583966598432061 1.8409201581623016 0.0656332598786408 1.0 0.564404198252883 14 P01130,Q15904 2 +Abnormal placenta morphology 0.7341954204250588 1.8378912575761064 0.0660784306076078 1.0 0.564404198252883 9 P16278 1 +Cardiovascular calcification 0.733872634104151 1.836517280061034 0.06628118881643 1.0 0.564404198252883 9 P01130,P04062 2 +Inflammation of the large intestine 0.6815582809662597 1.8331569930549352 0.0667792275089107 1.0 0.564404198252883 12 P08183 1 +Neck muscle weakness 0.6424060361234089 1.8308181895901057 0.067127684445525 1.0 0.564404198252883 16 P11047,Q99720,P07602 3 +Somatic sensory dysfunction 0.4672393230033483 1.830368968558499 0.0671947846628744 1.0 0.564404198252883 108 P01889,O14773,P54802,Q8IV08,P06280,O00170,P05067,P07686,O00400,P07602,O95831,P11166 12 +Hypopigmented skin patches 0.5712716856532782 1.8298300597100297 0.067275354391554 1.0 0.564404198252883 29 Q8IZA0,P53634,Q9BXW9,P49459,P07602 5 +Xanthelasma 0.9809863339275112 1.8272488159277895 0.0676623671685687 1.0 0.564404198252883 2 P01130 1 +Tendon xanthomatosis 0.9809863339275112 1.8272488159277895 0.0676623671685687 1.0 0.564404198252883 2 P01130 1 +Schizophrenia 0.6181875207116927 1.826533338467319 0.0677699642249125 1.0 0.564404198252883 19 P07602,P04062 2 +Abnormal choroid morphology 0.5652608532602384 1.826411370660796 0.0677883203836968 1.0 0.564404198252883 31 O43505,Q14118,Q9Y619,Q9Y6K9,Q10713,P29317,P04439 7 +Hypointensity of cerebral white matter on mri 0.753049723339819 1.825419022696607 0.0679378208342442 1.0 0.564404198252883 8 P49459,P07602 2 +Recurrent abscess formation 0.8736850033938868 1.821335140738836 0.068555927812874 1.0 0.5663849950131705 4 P49459,P53634 2 +Parkinsonism with favorable response to dopaminergic medication 0.6901522405480764 1.818827081766878 0.0689378153052899 1.0 0.5677273950093116 11 P07602 1 +Bilateral tonic clonic seizure with generalized onset 0.689936242849281 1.8178447330409404 0.0690878673753196 1.0 0.5677273950093116 11 Q13510,P04062 2 +Abnormal atrioventricular conduction 0.6534485278759639 1.816587168399416 0.0692803496747964 1.0 0.5680595612344095 14 P06280 1 +Calcification of the aorta 0.818109124741665 1.8152107979532788 0.069491520936689 1.0 0.5680595612344095 5 P01130 1 +Progressive visual loss 0.5928514157970164 1.810196301649078 0.0702653509435522 1.0 0.5700458350558127 24 O75503,O14773,P50897 3 +Leukonychia 0.7698115673999864 1.805002719691443 0.0710742564469311 1.0 0.5700458350558127 7 Q14574 1 +Abnormality of nail color 0.7698115673999864 1.805002719691443 0.0710742564469311 1.0 0.5700458350558127 7 Q14574 1 +Abscess 0.6869712904174177 1.8043505954302437 0.0711763627948316 1.0 0.5700458350558127 11 P49459,P53634 2 +Cerebral calcification 0.5555581414853391 1.8026592937689687 0.0714417387710011 1.0 0.5700458350558127 33 O00584,Q14118,P05067,P53634,P11166 5 +Disproportionate short limb short stature 0.6011434084825888 1.8024004240435905 0.0714824285386552 1.0 0.5700458350558127 22 Q15643,Q7LGA3,Q14739,Q9UBM7,Q32P28,Q15392 6 +Generalized hyperkeratosis 0.8142017050937813 1.800111166197271 0.0718430868042141 1.0 0.5700458350558127 5 P04066 1 +Abnormality of the axillary hair 0.7461025556310353 1.7966813757194335 0.0723862173038423 1.0 0.5701339556275424 8 Q14574,Q02487 2 +Cerebral white matter atrophy 0.5904513789113552 1.7961057936413451 0.0724776932048871 1.0 0.5701339556275424 24 O75503 1 +Macular purpura 0.6356069599876546 1.7960125849016215 0.0724925155498006 1.0 0.5701339556275424 16 Q6YHK3,O00170,P04062,P10644 4 +Gingival overgrowth 0.5741848284366725 1.7956182505071354 0.0725552512973075 1.0 0.5701339556275424 27 Q14739,Q9UBM7,O00754,P16278,P10644 5 +Onychogryposis 0.8667569832707959 1.795407423979732 0.0725888105001275 1.0 0.5701339556275424 4 P53634,Q9Y6K9 2 +Saccadic smooth pursuit 0.8666014917819651 1.794824975843049 0.0726815901883495 1.0 0.5701339556275424 4 Q10713,O14773 2 +Diabetes insipidus 0.6414291280573492 1.7900749121221828 0.0734418693157581 1.0 0.5710562270890864 15 Q9Y6N7,P01889,P06280 3 +Dysgraphia 0.6341544838303266 1.788560860551757 0.0736855659389812 1.0 0.5710562270890864 16 P60866,Q15056,P05067,P49768,Q9NUM4 5 +Progressive gait ataxia 0.6715378655425347 1.7863629954335816 0.0740405031077831 1.0 0.5710562270890864 12 O14773 1 +Abnormality of the biliary system 0.4704370721002284 1.78404101665103 0.0744170004778885 1.0 0.5710562270890864 118 Q14108,P04066,Q13510,P04062,O15118,P61916,Q14739,Q9UBM7,Q15904,Q10713,P38571,P07602,P10644,P11166 14 +Abnormal blistering of the skin 0.5831763862955802 1.783443452758198 0.0745141451868314 1.0 0.5710562270890864 25 Q14574,Q02487,Q9Y6K9,P01889 4 +Cardiorespiratory arrest 0.8634698130654224 1.783089301995156 0.0745717676155379 1.0 0.5710562270890864 4 O43772,P13473 2 +Abnormal pericardium morphology 0.701051313523864 1.7791614365180677 0.075213298723276 1.0 0.5733100680005105 10 Q14108,P01889 2 +Hyperhidrosis 0.5574697815052995 1.7759049181979625 0.0757485901958017 1.0 0.5747257507252052 31 O00170,P04066,P01889,P07686 4 +Type ii lissencephaly 0.9679144385026738 1.7755993875801164 0.0757989710284001 1.0 0.5747257507252052 2 P07942 1 +Recurrent gastroenteritis 0.8593646223493059 1.7676916217970748 0.0771124713958013 1.0 0.5827680215322036 4 O00754 1 +Restrictive ventilatory defect 0.6673242890373158 1.7666213950355822 0.0772916554507818 1.0 0.5831661728774212 12 P16278 1 +Female sexual dysfunction 0.7757408846561722 1.765536022387923 0.0774737216603498 1.0 0.5834931312785381 6 P01889,O00170 2 +Psoriasiform dermatitis 0.8581930563005871 1.7632944927903704 0.0778508336722088 1.0 0.5845152169851507 4 P01889,P10321 2 +Uveitis 0.7165055650696863 1.762321587786326 0.0780149784914658 1.0 0.584605118067317 9 P01889 1 +Myoclonus 0.4555432418908466 1.761721092880389 0.0781164322623573 1.0 0.584605118067317 102 Q14108,O14773,Q13510,P04062,P04080,O75503,Q9Y4G8,P02792,P67870,Q9H0U9,Q10713,P05067,P50897,P07602,Q01105,P11166 16 +Hyperorality 0.7745067296531133 1.7606566929932146 0.0782965268178712 1.0 0.5850032230638355 6 P49768,Q14203,Q9NUM4 3 +Dermatological manifestations of systemic disorders 0.4697188740378948 1.759647466788379 0.0784675980867262 1.0 0.5850136225018217 74 P04066,O15118,P61916,Q14739,Q15904,O43772,P38571,O75844,P10644 9 +Bifid tongue 0.8032405359807113 1.7576596307998158 0.0788054405570406 1.0 0.5850136225018217 5 Q9UBM7 1 +Abnormality of cardiovascular system electrophysiology 0.4693095803661545 1.7573942504004274 0.0788506326639681 1.0 0.5850136225018217 120 P42892,P01889,Q02487,P04062,Q07954,P01130,P13473,P06280,P10253,O43772,P07602 11 +Spinal muscular atrophy 0.6535168690022437 1.7569142656333931 0.0789324236867967 1.0 0.5850136225018217 13 Q13510 1 +Abnormality of skin physiology 0.4541266379087667 1.755770614990646 0.0791275837619893 1.0 0.585518717725154 101 P01889,P49768,P78536,Q92542,Q07954,P28070,Q15126,Q14739,Q9UBM7,O00170,P49459,Q9Y6K9,P38571,P02786,Q8ND04,P53634,P10321 17 +Bulbar signs 0.6524441962944141 1.7517426843229285 0.0798180636864573 1.0 0.5876747347366768 13 P07602,P04062,Q92734,Q99720,Q15043 5 +Abnormality of the gallbladder 0.5297242442583907 1.746442884897734 0.0807340235323665 1.0 0.5876747347366768 38 P07602,P04066,P04062,Q9UBM7 4 +Lymphedema 0.6258686680583829 1.745943485339154 0.0808207726148939 1.0 0.5876747347366768 16 Q14739,P06280 2 +Vacuolated lymphocytes 0.9845468053491828 1.7449810098477008 0.0809881746139669 1.0 0.5876747347366768 3 P04066,O00754 2 +Angiokeratoma 0.9845468053491828 1.7449810098477008 0.0809881746139669 1.0 0.5876747347366768 3 P04066,P06280 2 +Hamartoma of tongue 0.7999359760955302 1.7448350180235026 0.0810135913354141 1.0 0.5876747347366768 5 O43924,Q96PY6 2 +Elevated circulating alanine aminotransferase concentration 0.7121762078155152 1.743744537108274 0.0812036455590592 1.0 0.5876747347366768 9 Q15904,P10253 2 +Diffuse cerebral atrophy 0.5984780008442518 1.7396125151241812 0.0819270801969564 1.0 0.5894497752438758 20 Q06787,P07602,Q10713,P16278 4 +Gingival bleeding 0.6723123223245345 1.7373740981042225 0.0823211601394726 1.0 0.5894497752438758 11 Q14108,P04062 2 +Abnormal erythrocyte sedimentation rate 0.7529587992972994 1.737146233264753 0.0823613624654431 1.0 0.5894497752438758 7 P01889,P28070 2 +Metaphyseal cupping 0.8510665113893762 1.7365206110112794 0.0824718232174186 1.0 0.5894497752438758 4 Q15643,Q14739 2 +Abnormal intraocular pressure 0.7511123856060812 1.7296877137603723 0.083686084998815 1.0 0.5902082601076081 7 P04439 1 +Abnormality of the pharynx 0.4987506134341665 1.7276459124916244 0.0840517260762363 1.0 0.5902082601076081 48 P15586,P54802,Q13510,P16278 4 +Sea blue histiocytosis 0.9794947994056468 1.7268770083780365 0.0841897543976659 1.0 0.5902082601076081 3 P61916,P16278 2 +Abnormal blood potassium concentration 0.6471222754179169 1.7260464501139463 0.0843390564924333 1.0 0.5902082601076081 13 Q13423,O00170,P11166 3 +Hypoplastic vertebral bodies 0.7656243283535704 1.725482221791794 0.0844406049803687 1.0 0.5902082601076081 6 Q14739,P16278 2 +Papule 0.5994203224617104 1.7239119183079363 0.084723745423491 1.0 0.5902082601076081 19 P01889,Q07954 2 +Depressed nasal ridge 0.5868747019750475 1.7208085136203757 0.0852855770195533 1.0 0.5902082601076081 22 O00754,P16278 2 +Purpura 0.5988121981762539 1.7205684473025296 0.0853291631695034 1.0 0.5902082601076081 19 Q6YHK3,O00170,P04062,P10644 4 +Respiratory arrest 0.7277600150210232 1.7204418346664103 0.0853521580589826 1.0 0.5902082601076081 8 Q9H0U9,O43772,P13473 3 +Toxemia of pregnancy 0.7636599433370923 1.7176898938261729 0.0858531937025102 1.0 0.5902082601076081 6 O43772 1 +Arm dystonia 0.7633776449186569 1.716569681626541 0.0860578260220563 1.0 0.5902082601076081 6 P02792 1 +Heart block 0.57187838901192 1.715666457206055 0.0862231073681387 1.0 0.5902082601076081 25 O43772,Q07954,P06280 3 +Premature ventricular contraction 0.7467804418752946 1.7121708829497166 0.0868651816360546 1.0 0.5904387737126229 7 Q14126,O43772 2 +Bone marrow foam cells 0.9750371471025262 1.710891564932694 0.0871011320398158 1.0 0.5904387737126229 3 P61916,O15118 2 +Recurrent aspiration pneumonia 0.7462126416148576 1.7098730377756473 0.0872893532312213 1.0 0.5904387737126229 7 Q13510,P04062 2 +Frontotemporal dementia 0.6662854977215645 1.7097149029063743 0.0873186055606987 1.0 0.5904387737126229 11 P49768,P05067,Q9NUM4 3 +Alkalosis 0.7903147118319201 1.707429206752143 0.0877423056004607 1.0 0.5906334218396753 5 P01889,O00170 2 +Disproportionate short trunk short stature 0.7901100974637406 1.706632647783567 0.0878903530112835 1.0 0.5906334218396753 5 P16278 1 +Sudden death 0.5537940893134975 1.7040388717929864 0.0883738253776049 1.0 0.5914878745204762 28 Q14126,P01130,Q02487,P01889 4 +Abnormal metacarpal morphology 0.5406976289343205 1.703583080514315 0.0884590046161517 1.0 0.5914878745204762 33 O43924,Q15643,Q9H173,Q14739,Q96PY6,Q32P28,P16278,P10644,Q9NX62 9 +Petechiae 0.664188494596207 1.7000746675798393 0.0891168815744634 1.0 0.5931907814448584 11 Q6YHK3,P04062,P10644 3 +Abnormal macular morphology 0.5584139143487007 1.697790718584075 0.0895472682925786 1.0 0.5931907814448584 27 P04439,Q13510,P50897 3 +Aplasia hypoplasia involving the sinuses 0.7568056765028004 1.690463589985474 0.0909392983149799 1.0 0.595422417001872 6 P04066,P10644 2 +Young adult onset 0.6617003494732034 1.6886254822345348 0.0912912241522747 1.0 0.595422417001872 11 P07602 1 +Heparan sulfate excretion in urine 0.9679317446150196 1.6853904920293 0.0919132568482019 1.0 0.5975632069097827 3 P15586 1 +Abnormality of the phalanges of the hallux 0.8369682448783866 1.6834269631852032 0.0922924672214917 1.0 0.5984082614501786 4 Q9ULC3,Q96PY6 2 +Cerebellar cortical atrophy 0.8361423377727231 1.6803116461367682 0.0928966963120974 1.0 0.6006364235606859 4 Q9H173 1 +Mixed hearing impairment 0.7371648446537464 1.673200204021057 0.0942878902142041 1.0 0.6039372059936944 7 O00754 1 +Abnormal auditory evoked potentials 0.7161332566654783 1.6718541617821483 0.0945530835383374 1.0 0.6039372059936944 8 P07602 1 +Female hypogonadism 0.7799711375491314 1.6671091634198132 0.0954927003819317 1.0 0.6039372059936944 5 O00170,O75844 2 +Sparse or absent eyelashes 0.5587731098406599 1.6670370028206332 0.0955070473192871 1.0 0.6039372059936944 26 Q14574,O75844,Q02487,Q07954 4 +Bilateral tonic clonic seizure with focal onset 0.8323939922095146 1.666166333648935 0.0956802894511466 1.0 0.6039372059936944 4 P07602 1 +Tongue nodules 0.8320451843043947 1.6648494804898215 0.0959427893456927 1.0 0.6039372059936944 4 O43924,Q96PY6,Q2M1P5 3 +Elevated serum acid phosphatase 0.8315932664697425 1.6631432219799345 0.096283769807834 1.0 0.6039372059936944 4 P07602 1 +Fatigue 0.4417211499622513 1.662179300948512 0.0964768290032969 1.0 0.6039372059936944 83 P01889,P04062,Q13423,Q14739,P02792,P06280,O00170,P07602,P10644,Q4J6C6 10 +Supravalvular aortic stenosis 0.7344124726066663 1.6620233122171677 0.0965081003438914 1.0 0.6039372059936944 7 P01130 1 +Joint stiffness 0.4806233749493215 1.661573068631993 0.0965984069654417 1.0 0.6039372059936944 59 P01889,P15586,P54802,O00754,P16278 5 +Collectionism 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Lack of insight 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Eeg with continuous slow activity 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Expressive aphasia 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Senile plaques 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Alexia 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Grammar specific speech disorder 0.8309476534089348 1.6607053860140664 0.0967726311586409 1.0 0.6039372059936944 4 P49768,Q9NUM4 2 +Aplasia hypoplasia involving the nose 0.5447002654574312 1.6603304132720835 0.0968480006180561 1.0 0.6039372059936944 29 O94992,P63241,Q8NB90,Q5KU26,P49459,O75844,P10644 7 +Postaxial polydactyly 0.5572834801780067 1.6578721462767378 0.0973432752732219 1.0 0.6039737537140688 26 O43924,Q96J42,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q10713,O00459 8 +Central apnea 0.6920915254726462 1.6571573781245457 0.09748766113601 1.0 0.6040566099959762 9 P07602,Q10713 2 +Epiphora 0.7759614624837298 1.6514511108806096 0.0986464957119921 1.0 0.6076081304425054 5 Q07954 1 +Abnormality of the metacarpal bones 0.5045601043970432 1.65109172906906 0.0987198459222205 1.0 0.6076081304425054 41 O43924,Q15643,Q9BXW9,Q9H173,Q14739,Q9UBM7,Q96PY6,Q32P28,P16278,P10644,Q9NX62 11 +Fatiguable weakness of proximal limb muscles 0.8274850337096961 1.647625328414708 0.0994295795941582 1.0 0.6104174014490962 4 Q92734 1 +Abnormal larynx morphology 0.5449112301800204 1.6475692274876974 0.0994410994551564 1.0 0.6104174014490962 28 P07602,Q13510,Q14739 3 +Septo optic dysplasia 0.8264731187387501 1.643801188656455 0.1002172757644646 1.0 0.6109184668029637 4 Q9Y6N7 1 +Prominent sternum 0.934640522875819 1.6437696352613644 0.1002237957659266 1.0 0.6109184668029637 2 P16278 1 +Unexplained fevers 0.745041331581252 1.6436050600136267 0.1002578080753022 1.0 0.6109184668029637 6 Q9HC07,P07602 2 +Elevated circulating growth hormone concentration 0.9343434343434353 1.642590914664235 0.1004676017903569 1.0 0.6109184668029637 2 O00170 1 +Pituitary prolactin cell adenoma 0.9343434343434353 1.642590914664235 0.1004676017903569 1.0 0.6109184668029637 2 O00170 1 +Venous thrombosis 0.6297896629411224 1.6419293014118144 0.100604656573308 1.0 0.6109184668029637 13 P01889,P10644 2 +Pleural effusion 0.6514390525618314 1.6412866683820808 0.1007379221739241 1.0 0.6109184668029637 11 P01889 1 +Multiple prenatal fractures 0.7082629941852128 1.6388553568746744 0.1012433871276092 1.0 0.6109184668029637 8 Q32P28,P06753,O75718,Q14739 4 +Abnormal libido 0.8247489157092395 1.637283572331985 0.1015712318009827 1.0 0.6109184668029637 4 O00170 1 +Hypocholesterolemia 0.7077407605456398 1.63666268892526 0.1017009690796901 1.0 0.6109184668029637 8 P07602 1 +Hyperlipidemia 0.5307316450864263 1.6365687255439807 0.1017206147761942 1.0 0.6109184668029637 33 P01130,P28070,P06280,O75844,P38571 5 +Anophthalmia 0.6394040512362911 1.634879076940862 0.1020743994157875 1.0 0.6109184668029637 12 Q96J42,O43505,Q14118 3 +Recurrent infection of the gastrointestinal tract 0.7271313794224172 1.6324106652330956 0.1025930038783597 1.0 0.6126343884446096 7 O00754 1 +Incoordination 0.4608137450749815 1.6312684384037723 0.1028336899727146 1.0 0.6128434346835955 71 O14773,Q13510,P04062,O75503,P11047,O00754,P07602,Q01105 8 +Morning myoclonic jerks 0.93137254901961 1.6308026305518877 0.1029319722205444 1.0 0.6128434346835955 2 Q14108 1 +Tetraplegia 0.627167741659062 1.629149448773607 0.103281385342115 1.0 0.6128434346835955 13 O95831,Q13423,Q8NBF2,Q92734 4 +Communicating hydrocephalus 0.7702434184981385 1.6290959882050975 0.1032927003794259 1.0 0.6128434346835955 5 O00754 1 +Subcortical band heterotopia 0.7694372940041048 1.6259420159218247 0.1039619909218121 1.0 0.6130230958912031 5 P07942,P43034 2 +Subcortical heterotopia 0.7694372940041048 1.6259420159218247 0.1039619909218121 1.0 0.6130230958912031 5 P07942,P43034 2 +Infectious encephalitis 0.6665866824490503 1.6258204075505862 0.103987865723844 1.0 0.6130230958912031 10 P01889,Q14739 2 +Congenital hypothyroidism 0.8192208856777795 1.6163735069887646 0.106013582766979 1.0 0.6217844994348262 4 Q13423 1 +Mitral stenosis 0.7656284636577764 1.6110322389912823 0.1071726958747687 1.0 0.6250622750282703 5 P04062,O75844 2 +Abnormalities of placenta or umbilical cord 0.5992283093209005 1.6077140342180132 0.107897823457203 1.0 0.6250622750282703 16 P16278 1 +Abnormal hypothalamus morphology 0.7642204612140668 1.605517421986249 0.1083799822349396 1.0 0.6252278901062999 5 P19022,O43924 2 +Macular atrophy 0.7196550383866716 1.60193764488932 0.1091693989204583 1.0 0.6252278901062999 7 P04439 1 +Molar tooth sign on mri 0.7195142369696664 1.601363124356263 0.1092965152348919 1.0 0.6252278901062999 7 O43924,Q10713 2 +Peripheral opacification of the cornea 0.943807726624182 1.5986495097090243 0.1098985022418967 1.0 0.6252278901062999 3 P01130 1 +Hepatic fibrosis 0.5278365647759145 1.598470663949349 0.1099382691547192 1.0 0.6252278901062999 32 Q13510,P04062,Q15904,Q10713,P38571 5 +Pustule 0.8136806674620958 1.5953973916023774 0.1106233989461502 1.0 0.6262491709500894 4 P53634,P78536 2 +Osteopenia 0.4551812650265097 1.594431405779343 0.1108394429040897 1.0 0.6262491709500894 72 Q14108,Q9BZH6,P04062,O00170,O00754,Q32P28,O75844,P07602,P10644 9 +Abnormality of visual evoked potentials 0.5724655537768731 1.5937768497815838 0.1109860244395277 1.0 0.6262491709500894 20 O75503 1 +Hepatitis 0.6025080136036832 1.5923412179078915 0.1113080563360426 1.0 0.6272984593021477 15 Q9Y619,Q9H9C1,P11717 3 +Thoracolumbar kyphosis 0.7603173561213472 1.590221235884179 0.1117849453797177 1.0 0.6284495100006082 5 O00754 1 +Occipital encephalocele 0.8116368568568754 1.5876544383686808 0.1123645010004514 1.0 0.6309383064702574 4 P07942,O43505 2 +Abdominal obesity 0.730764835050962 1.5865362283030606 0.1126177206920366 1.0 0.6314384483628657 6 O75312,O00170 2 +Submucous cleft of soft and hard palate 0.550486285874196 1.586051997206612 0.1127275147511146 1.0 0.6314384483628657 25 Q7LGA3,P62266,O43505,Q14118,Q9Y619,O75844,Q15392,Q08J23 8 +Oromandibular dystonia 0.7581534154756725 1.581735467329157 0.1137099723931953 1.0 0.6330252037872264 5 Q99720 1 +Capillary hemangioma 0.7294967887121582 1.5814571968996718 0.1137735383834002 1.0 0.6330252037872264 6 Q7LGA3 1 +Nail pits 0.9185977421271556 1.5800961541517011 0.1140848479242837 1.0 0.6330252037872264 2 P10321 1 +Broad based gait 0.5540627991654397 1.5799406282267083 0.1141204638193398 1.0 0.6330252037872264 24 O14773,Q9NUM4 2 +Psychosis 0.5217631278156344 1.5758798248889567 0.1150535013528726 1.0 0.6344457431061516 33 O15118,P61916,P02792,O00170,P49768,Q9NUM4,P10644 7 +Stillbirth 0.6155841591415877 1.572522199060394 0.1158294949997844 1.0 0.6355242227688876 13 Q15643,P04062,O75844 3 +Fever 0.434288845449244 1.5680302596308662 0.1168740706370012 1.0 0.6376206693923976 82 P01889,Q13510,P28070,Q0IIM8,Q14739,P06280,Q9NR50,Q9HC07,P10253,P38571,P07602,P10644 12 +Loss of voice 0.9334983954042064 1.561522388340402 0.1184005456183647 1.0 0.6395336532527215 3 Q13510 1 +Ventricular tachycardia 0.6021336115642117 1.5608015060579743 0.1185705919977704 1.0 0.6395336532527215 14 Q14126,O43772 2 +Hypokinesia 0.6130781488944629 1.5602367382030895 0.1187039468279198 1.0 0.6395336532527215 13 O95831,P13473,P04062 3 +Opsoclonus 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.6395336532527215 2 P04062 1 +Hip osteoarthritis 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.6395336532527215 2 P01889 1 +Saccadic oscillation 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.6395336532527215 2 P04062 1 +Extramedullary hematopoiesis 0.8018829145897026 1.5506690861472192 0.1209810065415273 1.0 0.6418885461365712 4 Q14739 1 +Multifocal cerebral white matter abnormalities 0.7492215579674065 1.546671623845992 0.1219424489429121 1.0 0.6439645703551187 5 Q9Y3Z3,P10253 2 +Weak cry 0.6488664079067373 1.546209083393006 0.1220540805017382 1.0 0.6439645703551187 10 P11047,Q13510 2 +Nasogastric tube feeding in infancy 0.6663989754970626 1.5454909816850544 0.1222275486031949 1.0 0.6439645703551187 9 P07602,Q92734 2 +Biparietal narrowing 0.6093423904431989 1.5419004665368925 0.1230977825783234 1.0 0.6470704420593744 13 O43924,Q10713,Q9UBM7,Q2M1P5 4 +Subcutaneous hemorrhage 0.4972403877818726 1.5390022002739887 0.1238037590914558 1.0 0.647826707618174 39 Q14108,Q6YHK3,P04062,Q9BXW9,O00170,P10644 6 +Delayed ability to sit 0.5857609552876821 1.5371737864339314 0.1242507577599565 1.0 0.6487014807556967 16 Q9H2M9,P43034,Q14118,P10253,Q10713 5 +Alzheimer disease 0.907605466428999 1.5364556323593737 0.1244266713811095 1.0 0.6487014807556967 2 P05067 1 +Irritability 0.4348472496813594 1.5349952742964814 0.1247849888461332 1.0 0.6487014807556967 80 O94992,P01889,P49768,Q13510,Q8NBF2,Q0IIM8,Q06787,Q5KU26,O43772,P50897,O95831,P07602,Q9NUM4,P11166 14 +Red eye 0.5617373091953075 1.5330453168044686 0.1252646896481972 1.0 0.6487014807556967 20 P02786,P01889,Q14739 3 +Primitive reflex 0.7028032761290152 1.5330219003887378 0.1252704589434214 1.0 0.6487014807556967 7 P49768,P17900 2 +Hypomimic face 0.5965741746897981 1.5327402115333677 0.125339877179313 1.0 0.6487014807556967 14 P04062,P02792 2 +Abnormal metatarsal morphology 0.5416218027139574 1.5318694680277214 0.1255546491963841 1.0 0.6487014807556967 25 Q9H173,Q9ULC3,O43505,Q9UBM7,Q96PY6,Q15392,P10644 7 +Coarse hair 0.5611727633539583 1.529840485224384 0.1260562177335653 1.0 0.6487014807556967 20 P15586 1 +Hypoplasia of the odontoid process 0.7448262665932297 1.5293958815603794 0.1261663328143125 1.0 0.6487014807556967 5 P16278 1 +Abnormal iliac wing morphology 0.6258200341739057 1.522295541201859 0.1279350448011604 1.0 0.6531346141011625 11 Q15643,O95831,P16278 3 +Adrenal hypoplasia 0.6430335149348452 1.5199011249652945 0.1285358276959405 1.0 0.6533275260920048 10 O75844,Q9Y6N7 2 +Abnormal chorioretinal morphology 0.5208679698658418 1.519774357438872 0.1285676959446826 1.0 0.6533275260920048 30 O43505,Q14118,Q9Y619,Q9Y6K9,Q10713,P04439 6 +Weak voice 0.6798219215538336 1.518932499727098 0.1287794874397962 1.0 0.6533275260920048 8 Q14203,P04062,P02792,O75787 4 +Abnormality of the odontoid process 0.7135745565412184 1.5175535773694422 0.1291269772569916 1.0 0.6534708605555736 6 P16278 1 +Cyanosis 0.5685421303197981 1.5141097730639552 0.1299980003562733 1.0 0.6548332785048528 18 O75844,P04066,O43772 3 +Vertebral hypoplasia 0.6239539112405499 1.5135865824973078 0.1301307262801494 1.0 0.6548332785048528 11 Q14739,P16278 2 +Metatarsus valgus 0.9200594353640416 1.5130914765163477 0.1302564243793817 1.0 0.6548332785048528 3 Q9H173,O43505 2 +Progressive spasticity 0.5743104121313853 1.5097462749271573 0.1311081785677093 1.0 0.6567181017473495 17 P07602 1 +Underdeveloped nasal alae 0.5423665198753221 1.5094965993526668 0.1311719236845177 1.0 0.6567181017473495 24 O94992,P63241,Q8NB90,Q5KU26,P49459 5 +Focal impaired awareness seizure 0.5539295547371691 1.5082913776602314 0.1314799690296157 1.0 0.6567181017473495 21 P19022,Q01105,P67870,P22466 4 +Absent or minimally ossified vertebral bodies 0.7900533190223793 1.5057497222975822 0.1321314344940063 1.0 0.6567181017473495 4 Q15643 1 +Telangiectasia 0.4960390907418687 1.504358166653826 0.1324891695445191 1.0 0.6567181017473495 38 P10619,Q8IZA0,P06280 3 +Impaired mastication 0.6956864978321975 1.503830159253218 0.1326251035258403 1.0 0.6567181017473495 7 P11047,P01889 2 +Ankle clonus 0.5907192390781759 1.5031210237151005 0.1328078383261153 1.0 0.6567181017473495 14 P07602,Q15043 2 +Opisthotonus 0.5322900970375417 1.5028912101341088 0.1328671000373953 1.0 0.6567181017473495 26 P07602,Q99720,P11117 3 +Dysphagia 0.4606351769550406 1.5022188222665387 0.133040605353726 1.0 0.6567181017473495 143 P15586,P61916,P67870,P05067,P07602,Q14108,Q8IZA0,O75874,Q14739,P49768,P06753,Q13510,O15118,Q8N0X7,P02792,P63241,P11047,Q06787,Q99720,P01889,P04062,Q96PY6,Q92734,Q01105 24 +Impaired smooth pursuit 0.5661558916932641 1.5010128460155965 0.1333522390199997 1.0 0.6567181017473495 18 O00754,P02792 2 +Frontotemporal cerebral atrophy 0.7094446254966738 1.5009419497922574 0.133370576723443 1.0 0.6567181017473495 6 P49768,Q9UQN3,Q9NUM4 3 +Abnormal cardiac ventricular function 0.5560144882793756 1.5005173327207515 0.1334804471447432 1.0 0.6567181017473495 20 P01130,P10253 2 +Micrographia 0.9160371327331298 1.4985915280582702 0.1339796318915564 1.0 0.6577700777636585 3 P02792 1 +Myoclonic seizure 0.4639878931602427 1.4960642199515255 0.1346369207749611 1.0 0.6582103354381643 56 Q13510,P04062,O75503,Q8NB90,P07686,P16278,P07602 7 +Abnormal eyelid physiology 0.6743549963343834 1.495771423020018 0.1347132306908953 1.0 0.6582103354381643 8 P49588,P04350,O14656,P02792 4 +Ventricular hypertrophy 0.4875377750752601 1.4944089694264122 0.1350687586387209 1.0 0.6582103354381643 40 P06280,O00170,P10253,O43772,O75844 5 +Right ventricular cardiomyopathy 0.7075560777771254 1.4933411716805935 0.135347903529182 1.0 0.6588741660713084 6 Q02487 1 +Limb dystonia 0.5771976851941165 1.4921065876968929 0.1356712051738586 1.0 0.6593334942021163 16 Q99720,P02792 2 +Agyria 0.7352946432710575 1.4918887782101318 0.1357283049886786 1.0 0.6593334942021163 5 P43034,Q14118 2 +Thickened calvaria 0.6730247281301889 1.4901308154530546 0.1361898430810675 1.0 0.65939307351756 8 O00754 1 +Premature loss of primary teeth 0.9135215453194654 1.4895225588082404 0.1363498174796218 1.0 0.65939307351756 3 P04080,P53634 2 +Pathologic fracture 0.5704751295528927 1.4891200966071627 0.1364557466671914 1.0 0.65939307351756 17 Q14108 1 +Aortic regurgitation 0.5343101216090216 1.4869795701121744 0.1370202068407267 1.0 0.6607282304082412 25 P01889,O00754,O75844 3 +Slow saccadic eye movements 0.6178953162226666 1.4852761777440708 0.1374706796943672 1.0 0.6614687852987684 11 Q8IV08 1 +Poor wound healing 0.7053287304685184 1.4843732904032816 0.1377099165831294 1.0 0.6614687852987684 6 P04062 1 +Xanthomatosis 0.9115978140094022 1.4825871183548995 0.1381841416990505 1.0 0.6621921967075085 3 P01130 1 +Duplication involving bones of the feet 0.5411073820323828 1.4772304369947546 0.1396138775523512 1.0 0.6662000178994498 23 O43924,Q96J42,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q10713 7 +Increased intracranial pressure 0.5517459218360274 1.4761977304357363 0.1398908186443443 1.0 0.6662000178994498 20 P60866,P07602,P10644,P01889 4 +Polar cataract 0.9093060262688596 1.4743246629762226 0.1403941978322 1.0 0.6662000178994498 3 P29317 1 +Pituitary growth hormone cell adenoma 0.7817165064612224 1.474059393846187 0.1404656003033113 1.0 0.6662000178994498 4 O00170 1 +Agitation 0.4982193471069581 1.4733337165594416 0.1406610735084748 1.0 0.6664414685242228 36 P42892,P04062,Q96PY6,P05067,P49768,P10644 6 +Epistaxis 0.5841524192814337 1.4698228929798898 0.1416097272064083 1.0 0.6684670947974621 14 P01889,P04062 2 +Recurrent cutaneous abscess formation 0.9078751857355128 1.469166128092526 0.1417877350663849 1.0 0.6684670947974621 3 P49459,P53634 2 +Retinal detachment 0.5602494790813627 1.468536201015349 0.1419586303268363 1.0 0.6684670947974621 18 P04439,Q9P273,O43505,Q14118 4 +Aganglionic megacolon 0.5663933423100309 1.4671318176656307 0.1423402002013154 1.0 0.6695799213551675 17 P42892,Q10713,Q9UBM7 3 +Spoken word recognition deficit 0.7270901511157 1.45956249299457 0.1444103537360348 1.0 0.674500233762027 5 P49768,Q9NUM4 2 +Thick lower lip vermilion 0.4662589708716462 1.4564738623777052 0.1452616699997064 1.0 0.6750567527204101 45 P04066,P15586,P06280,O00170,P11166 5 +Acne inversa 0.6981507777948698 1.4554482404369198 0.1455452096246394 1.0 0.6755246437887565 6 Q92542 1 +Thoracic kyphosis 0.5812379222410102 1.4550192078061936 0.1456639440213727 1.0 0.6755246437887565 14 O00754,P04062 2 +Bimanual synkinesia 0.9036983985211512 1.454108058892505 0.1459163496295716 1.0 0.6755246437887565 3 P19022 1 +Reduced visual acuity 0.4389347024089855 1.4535048401855766 0.1460836367962985 1.0 0.6755246437887565 119 Q6YHK3,P01889,P51798,O96000,Q9P273,O43505,Q9NR50,P11047,O00170,Q10713,P07686,O00459,P16278,P50897,P17900,P07602,Q15043,P06865 18 +Muscle flaccidity 0.9034638364545298 1.45326244313606 0.1461509006989043 1.0 0.6755246437887565 3 P13473 1 +Abnormal periventricular white matter morphology 0.4780399923209741 1.451109747726855 0.1467493026266766 1.0 0.6755246437887565 41 P07602,O75503 2 +Weight loss 0.4411192474362989 1.450326621007162 0.1469674588816438 1.0 0.6755246437887565 71 P42892,P01889,Q99720,P04062,P38571,O75844,P07602 7 +Abnormal blood transition element cation concentration 0.6007955575656216 1.4503023150477687 0.1469742337787685 1.0 0.6755246437887565 12 Q15904 1 +Agenesis of cerebellar vermis 0.9006979749596 1.4432915657329466 0.1489383547069762 1.0 0.68115656269758 3 O43924 1 +Respiratory failure requiring assisted ventilation 0.7227994000870832 1.4426435404283409 0.1491209113928964 1.0 0.6812201279923195 5 P10253 1 +Abnormality of the ischium 0.9001040986934624 1.441150733726826 0.1495421032257566 1.0 0.6812201279923195 3 Q8IZA0 1 +Memory impairment 0.4839086656466711 1.440641267550252 0.1496860554518944 1.0 0.6812201279923195 39 P07602,P05067,Q9NUM4 3 +Prenatal maternal abnormality 0.5981409885044426 1.4375231087941562 0.1505694114369031 1.0 0.6837815128572945 12 O43772 1 +Limb fasciculations 0.7719662330569791 1.4369698984656245 0.1507265468873315 1.0 0.6837815128572945 4 Q92734 1 +Premature loss of teeth 0.5870734947800669 1.4320845912504827 0.1521196137103242 1.0 0.6867791707446828 13 P04080,P53634,P51798,O75844 4 +Fibrous tissue neoplasm 0.5467951066087526 1.4306536866587294 0.152529492727363 1.0 0.6869628778157216 19 Q07954,Q15392 2 +Abnormal foot bone ossification 0.7693243201402209 1.4269166017889474 0.1536039349025628 1.0 0.6869628778157216 4 Q15643 1 +Fat malabsorption 0.6393092822320192 1.4268078124158012 0.1536352987045572 1.0 0.6869628778157216 9 P38571 1 +Ambiguous genitalia male 0.8951707015771426 1.4233680973567062 0.1546294756767636 1.0 0.6896345293746488 3 Q15392 1 +Gastrointestinal inflammation 0.5421891310397857 1.4215783595277098 0.1551486907335744 1.0 0.6896345293746488 20 P08183 1 +Tracheal stenosis 0.7173581328435981 1.4211769141792672 0.15526533430262 1.0 0.6896345293746488 5 Q9UBM7 1 +Sparse eyelashes 0.5511919422994915 1.41857576977361 0.1560227341422524 1.0 0.6909364115233273 18 Q14574,Q02487,O75844 3 +Hypopigmentation of the skin 0.4574770487658768 1.4156447402174224 0.156879545089108 1.0 0.6933985645836895 52 O75312,Q8IZA0,P53634,P51798,Q9BXW9,P49459,Q9Y6K9,P07602 8 +Joint contracture of the hand 0.4594614552500943 1.4126810077428116 0.1577495383106895 1.0 0.6950047816864334 48 P42892,Q8IZA0,Q9ULC3,Q9Y6K9,O75844,Q15392,P06753 7 +Abnormal neuron morphology 0.5046568663164428 1.412386374943423 0.1578362260769465 1.0 0.6950047816864334 30 Q13510,Q96PY6,Q92734,P49768,Q99720,Q9NUM4 6 +Motor neuron atrophy 0.5301677969899776 1.4118151793621556 0.1580043877798174 1.0 0.6950047816864334 23 Q13510,Q96PY6,Q92734,P49768,Q99720 5 +Kinetic tremor 0.4951759498120702 1.411690819310323 0.1580410177361406 1.0 0.6950047816864334 34 Q14108,P07602 2 +Ascending tubular aorta aneurysm 0.7144599528055124 1.4097387437087507 0.1586168400923175 1.0 0.6950047816864334 5 P01889,O75844 2 +Decreased urine output 0.875222816399291 1.4080016036676295 0.1591305951310111 1.0 0.6950047816864334 2 O43772 1 +Oliguria 0.875222816399291 1.4080016036676295 0.1591305951310111 1.0 0.6950047816864334 2 O43772 1 +Lacrimation abnormality 0.5485210194876681 1.4038085551637305 0.1603758657270844 1.0 0.6964355563361795 18 Q15043,Q07954 2 +Osteolysis involving bones of the upper limbs 0.633645379505478 1.4018911981610234 0.1609477392556373 1.0 0.6964355563361795 9 P53634 1 +Metatarsus adductus 0.5905242710348322 1.4008018026260691 0.1612733494536264 1.0 0.6964355563361795 12 Q9H2M9,Q9ULC3,Q9UBM7,Q15392,Q08J23 5 +Cholestasis 0.4264229067943786 1.4005213098177098 0.1613572666318528 1.0 0.6964355563361795 77 Q13510,O15118,P61916,Q14739,Q9UBM7,Q15904,P38571,P10644 8 +Abnormal delivery 0.5318494892675011 1.4000628707238552 0.1614944923478039 1.0 0.6964355563361795 22 Q6YHK3,O75718,Q9UBM7,Q9Y619,O75844,P06753 6 +Dyspnea 0.4258298271367436 1.3977652074277531 0.1621835855549633 1.0 0.6969543045570662 109 P01889,Q02487,Q13510,P04062,Q15643,P01130,Q96PY6,P06280,P11047,P10253,O75844,P07602,O95831,P10644 14 +Epidermal acanthosis 0.5893876141839584 1.3953152461633438 0.1629207965022225 1.0 0.6969543045570662 12 Q14574 1 +Abnormally ossified vertebrae 0.7103314846326072 1.3934405139410824 0.1634866216265602 1.0 0.6969543045570662 5 Q15643 1 +Hepatic failure 0.4547736843210651 1.393183396790832 0.1635643391971906 1.0 0.6969543045570662 52 P01889,Q13510,O15118,O43772,P38571 5 +Multiple lentigines 0.7100802854594022 1.3924486847476418 0.1637865705682797 1.0 0.6969543045570662 5 Q02750,P28482,P10644,Q06124 4 +Abnormal eyelash morphology 0.416336629739071 1.3884623167320878 0.1649963118985968 1.0 0.6969543045570662 82 O94992,Q02487,Q07954,Q9UBM7,Q5KU26,Q14574,O75844,Q4J6C6 8 +Periauricular skin pits 0.5779532695070502 1.386880474935521 0.1654782125298688 1.0 0.6969543045570662 13 P49459,Q07954 2 +Absent facial hair 0.6136228621090567 1.3865816061442913 0.1655693803342988 1.0 0.6969543045570662 10 Q07954 1 +Status epilepticus 0.4554585254543605 1.3842014155444309 0.1662967900524885 1.0 0.6969543045570662 49 P42892,P07602,Q13510,Q15392 4 +Ambiguous genitalia 0.521723438768004 1.3841312148924951 0.1663182804896128 1.0 0.6969543045570662 24 Q96PY6,Q9H0U9,Q9UBM7,Q15392 4 +Thickened nuchal skin fold 0.561759754449608 1.3817210232463808 0.1670573766888412 1.0 0.6969543045570662 15 Q15643,Q9NUM4 2 +Slowly progressive 0.4467098951348696 1.3799995962142573 0.1675867691543098 1.0 0.6978997342379117 60 O00584,Q8IV08,O14773 3 +Low levels of vitamin d 0.6283088184571672 1.3783871989627383 0.1680837735436657 1.0 0.6980272516908698 9 Q01968,P62913,Q7Z2Z2,P46783,Q5F1R6 5 +Cerebral palsy 0.5857893343541885 1.3779359848384052 0.1682230534986022 1.0 0.6980272516908698 12 Q6YHK3,O00170 2 +Decreased circulating antibody level 0.4555089973925398 1.3767234866073352 0.168597754457817 1.0 0.6987364928018412 47 P02786,Q15904,O00754,P13051 4 +Posterior pituitary dysgenesis 0.7056554439019957 1.374975268661678 0.1691391121546002 1.0 0.6999383366541355 5 Q9Y6N7 1 +Vasculitis 0.6457917924305429 1.3742953104218585 0.1693500216182406 1.0 0.7001496082276271 8 P01889,Q9Y3Z3 2 +Genu valgum 0.4842554064188434 1.3736869106182474 0.1695389022264288 1.0 0.7001496082276271 36 O75312,P51798,Q7LGA3,Q8N0X7,Q9ULC3,Q15056,Q9Y619,O00754,P16278,Q04721,Q9NX62 11 +Abnormal sacrum morphology 0.4944464288698305 1.3726615994124372 0.1698575723204889 1.0 0.7001496082276271 32 P01889,P04066,Q9ULC3,P43034,Q14739,Q15056 6 +Abnormal cornea morphology 0.4563103775338081 1.370468673092055 0.170540647900721 1.0 0.7013312995738838 156 O15347,Q9BXW9,P01130,Q7LGA3,Q9UBM7,P06280,Q14118,P04066,Q14739,P10619,O00754,P16278,P34913,Q13510,Q8ND04,P01889,P04062,Q9P273,Q9ULC3,O43505,Q15056,O75844 22 +Brisk reflexes 0.5192724923591078 1.3691649807711266 0.1709477098584644 1.0 0.7017532880209447 24 Q99720,P02792 2 +Pruritus 0.5227270043626981 1.3671330626507026 0.1715836016675385 1.0 0.7031114699443133 23 P38571,Q14739,Q07954 3 +Abnormal cry 0.5735084929192217 1.364807878403992 0.1723134419652958 1.0 0.7036349524340224 13 P11047,Q13510,Q9H0U9 3 +Bacterial endocarditis 0.8787080124491162 1.364061188576417 0.1725483085771957 1.0 0.7036349524340224 3 P04062 1 +Abnormality of the ankles 0.4548993527611255 1.362736528174597 0.1729655612180436 1.0 0.7037698474979533 44 Q14118,Q15056,O00754,O75844,P06753,P07602,Q15043 7 +Delayed puberty 0.4478225941853601 1.3591128129929058 0.1741108432547267 1.0 0.7051163244476591 56 Q14108,P04062,P06280,O00170,O75844,Q9Y6N7 6 +Hypoplasia of olfactory tract 0.8627450980392197 1.3586207264777466 0.1742668039078401 1.0 0.7051163244476591 2 O43924 1 +Central y shaped metacarpal 0.8627450980392197 1.3586207264777466 0.1742668039078401 1.0 0.7051163244476591 2 O43924 1 +Lobulated tongue 0.8627450980392197 1.3586207264777466 0.1742668039078401 1.0 0.7051163244476591 2 O43924 1 +Decreased circulating copper concentration 0.8771088594998563 1.3583042556048055 0.1743671604924797 1.0 0.7051163244476591 3 Q15904 1 +Abnormal tongue physiology 0.530654228837125 1.3553587488667032 0.1753032857008853 1.0 0.7054914163361636 20 P10253,Q13510,O95831 3 +Abnormal cerebral vascular morphology 0.4307985402296661 1.3542997248785698 0.1756407739029608 1.0 0.7054914163361636 71 Q6YHK3,P04062,P01130,P06280,P10253,P05067 6 +Abnormal paranasal sinus morphology 0.5161418327309986 1.3500247212345096 0.1770080532594324 1.0 0.7054914163361636 24 P28070,P04066,O00754,P10644 4 +Small epiphyses 0.7482549972942454 1.3467203040769156 0.1780703304631015 1.0 0.7054914163361636 4 Q15643 1 +Progressive microcephaly 0.4522873382452429 1.3443483025271303 0.1788357828160822 1.0 0.7054914163361636 45 O94992,Q5KU26,Q15043,P50897 4 +Metaphyseal chondrodysplasia 0.6976428170837579 1.3433250084317971 0.1791667576731817 1.0 0.7054914163361636 5 Q7Z2Z2,Q5F1R6,O95831 3 +Cutaneous photosensitivity 0.5103467812228528 1.338689137921233 0.1806718938406875 1.0 0.7082768973869615 25 Q14108,P04080,Q15126,Q9UBM7,Q9Y3Z3,Q9NP58 6 +Abnormality of lower lip 0.4352873812531744 1.3361127517025837 0.1815124226489974 1.0 0.7092020007135176 66 P04066,P04062,P15586,Q7LGA3,P06280,O00170,P11166 7 +Horizontal nystagmus 0.5174904125938156 1.3356015629846654 0.1816795390056966 1.0 0.7092020007135176 23 P07602,P04062,O14773,O95831 4 +Abnormal lumbar spine morphology 0.602271876827084 1.3348786844696932 0.1819160552162979 1.0 0.7095033964019742 10 O00754 1 +Prominent forehead 0.4194663818949625 1.332820977457492 0.1825905599137625 1.0 0.7105145034877751 77 O75312,P19022,P04066,Q15643,P15586,Q7LGA3,Q14739,Q06787,Q10713,O00754,Q15392,P29372,P11233,P11166 14 +Decreased circulating total igm 0.6178394080352313 1.3322081454162027 0.182791800680369 1.0 0.7105145034877751 9 Q15904 1 +Rhizomelia 0.5666354725509655 1.330627364668333 0.18331165377263 1.0 0.7118971108690382 13 Q9UBM7,Q15392 2 +Micromelia 0.512744001997184 1.3292220571491498 0.1837747200886379 1.0 0.7118971108690382 24 Q15643,O75874,Q14739,Q9UBM7,Q2M1P5,Q15392,P10644 7 +Pericardial effusion 0.6939937276317234 1.3289088048006057 0.1838780586169648 1.0 0.7118971108690382 5 Q14108 1 +Aspiration pneumonia 0.5044613335185596 1.3278475603333484 0.1842284714244604 1.0 0.7118971108690382 26 Q13510,P04062,P78318,Q92734,P16278,P06753 6 +Abnormality of adrenal morphology 0.4950873408944442 1.3252315644973056 0.1850943592595593 1.0 0.7142731170230168 28 Q9BZH6,O75844,P38571,Q9Y6N7,P10644 5 +Limb myoclonus 0.6658799630617798 1.3250471067422362 0.1851555277372538 1.0 0.7142731170230168 6 Q13510 1 +Multiple rib fractures 0.8541295306001223 1.324587010298455 0.1853081665855809 1.0 0.7142731170230168 2 Q15643 1 +Pulmonary fibrosis 0.5244239378488109 1.3194686566835854 0.1870124819683409 1.0 0.7174218341478 20 Q8IZA0 1 +Adult onset 0.4279041622166318 1.314560659693958 0.1886575989466679 1.0 0.7192639874868575 70 P04062,O15118,Q8IV08,Q15126,Q9Y4G8,P02792,Q06787,Q92734,P49768,P07602 10 +Action tremor 0.4409770483984527 1.3144634314796249 0.1886902964468813 1.0 0.7192639874868575 58 Q14108,P07602,O14773,Q99720 4 +Degeneration of the lateral corticospinal tracts 0.6632343373769402 1.3143392639605007 0.1887320596152224 1.0 0.7192639874868575 6 O00400 1 +Apraxia 0.4263731363695471 1.3128824642793433 0.1892225566677638 1.0 0.7192639874868575 71 Q96PZ0,O43924,O14773,P04062,Q7LGA3,Q8N0X7,Q9Y619,Q10713,P05067,P49768,Q9NUM4,P11166 12 +Muscle stiffness 0.5170623787156436 1.3124195121846756 0.1893786268710136 1.0 0.7192639874868575 22 Q9H173,Q15392,P06753,P07602,P11166 5 +Respiratory tract infection 0.4578473255374773 1.3117842754706102 0.1895929319659708 1.0 0.7192639874868575 168 P15586,P78318,P02786,P07602,P04066,Q15643,P51798,P54802,Q0IIM8,P10253,P49459,O00754,P16278,P53634,Q13510,P11047,P01889,P04062,Q15056,Q92734,P13051 21 +Esodeviation 0.4664126596657311 1.3102860195012562 0.1900990951721628 1.0 0.7192639874868575 39 O94992,O43924,P04062,Q9P273,Q5KU26 5 +Encephalocele 0.5523746663621606 1.307676617472049 0.1909830174786373 1.0 0.7192639874868575 14 P07942,Q10713,O43505 3 +Y shaped metacarpals 0.8630014858841014 1.3075633143402043 0.1910214667778491 1.0 0.7192639874868575 3 O43924,Q96PY6 2 +Duplication of phalanx of hallux 0.8630014858841013 1.3075633143402043 0.1910214667778491 1.0 0.7192639874868575 3 Q9ULC3,Q96PY6 2 +Lethal skeletal dysplasia 0.8626274150335442 1.3062191684553823 0.1914780360353583 1.0 0.7192639874868575 3 Q15643 1 +Breech presentation 0.6476648189204681 1.3058434620407635 0.1916057965816111 1.0 0.7192639874868575 7 Q9Y619,Q9UBM7,P06753 3 +Infantile muscular hypotonia 0.4239882984716711 1.3034983284867812 0.1924046866642976 1.0 0.7194985946997605 72 Q13510,P10253,O00754,P16278,P17900,P07602 6 +Neonatal alloimmune thrombocytopenia 0.7364714197402427 1.3018828894150296 0.1929564225046116 1.0 0.7202664840050685 4 Q6YHK3 1 +Abnormality of temperature regulation 0.4132400963743103 1.29931046752401 0.1938374035247783 1.0 0.7225933359743079 105 P01889,Q13510,P51798,P28070,Q0IIM8,Q14739,Q9H0U9,P06280,Q9NR50,P10253,O43772,P38571,P07602,P10644 14 +Restrictive behavior 0.6458655474903876 1.298402344770857 0.194149113830516 1.0 0.7225933359743079 7 P49768,Q9NUM4 2 +Sparse eyebrow 0.475993249781599 1.2950670717138637 0.1952970928977757 1.0 0.7225933359743079 35 Q14574,Q02487,Q07954 3 +Calcinosis 0.6851481919881863 1.2939637204648022 0.1956779525893317 1.0 0.7225933359743079 5 O75844 1 +Laryngeal dystonia 0.8591511413102253 1.293731652340237 0.1957581281469038 1.0 0.7225933359743079 3 P02792 1 +Increased vertebral height 0.8591381872213971 1.2936851315643103 0.1957742031739502 1.0 0.7225933359743079 3 O00754,Q04721 2 +Uric acid nephrolithiasis 0.8452168746286397 1.2894471588397074 0.1972426754869656 1.0 0.7234823655155135 2 P07741 1 +Macroscopic hematuria 0.8452168746286397 1.2894471588397074 0.1972426754869656 1.0 0.7234823655155135 2 P07741 1 +Decreased facial expression 0.4859727363737236 1.2874524356283197 0.1979366379667513 1.0 0.7236224433201615 30 P04062,P19525,P02792,O75787,Q06787,P06753,Q14203,Q15043,Q9BUK6 9 +Anteverted ears 0.8440285204991114 1.2847677179987531 0.1988734663542639 1.0 0.7256669186799081 2 O15347 1 +Dilation of virchow robin spaces 0.8440285204991099 1.284767717998747 0.1988734663542661 1.0 0.7256669186799081 2 P43034 1 +Frontal lobe dementia 0.7318050680318191 1.2841369394731603 0.1990940450608376 1.0 0.7256669186799081 4 P02792 1 +Abnormal immune system morphology 0.4505533619273743 1.2840469706635214 0.1991255210694325 1.0 0.7256669186799081 160 Q14126,Q9BXW9,P61916,Q9Y6K9,P02786,Q14108,P04066,P51798,Q14739,P49459,O00754,P16278,P49768,P53634,Q13510,O15118,P28070,Q15904,Q9Y3Z3,P38571,P10644,O75312,P01889,P04062 24 +Postural instability 0.5268263439365157 1.283337514648388 0.1993738549850603 1.0 0.7259980027497063 18 O75503 1 +Short thorax 0.681860707697679 1.2809780670426876 0.2002013700410603 1.0 0.72764204988876 5 Q15643 1 +Acquired abnormal hair pattern 0.6229788844972886 1.2768634624621114 0.2016504555468337 1.0 0.7293560536430934 8 O75844,P11166 2 +Focal emotional seizure 0.6051924518932598 1.276326889119417 0.2018399887629449 1.0 0.7293560536430934 9 Q01105 1 +Spotty hypopigmentation 0.8540239664985891 1.2753270354151007 0.2021935124277123 1.0 0.7293560536430934 3 P49459 1 +Skin ulcer 0.4802425825127343 1.2753240040312634 0.2021945849361981 1.0 0.7293560536430934 32 P01889,Q8IZA0,P04062,Q14739,Q9Y6K9 5 +Poor head control 0.4132802841672067 1.2722947492204115 0.2032684135154079 1.0 0.730247657484772 77 O94992,O96000,Q14118,P11047,Q5KU26,Q10713,P17900,P07602,P06865 9 +Absent hair 0.5638296685186424 1.2715713357977645 0.2035254666216968 1.0 0.730247657484772 12 Q07954 1 +Mild short stature 0.8527377280904229 1.27071260526978 0.2038309095295347 1.0 0.7306846756851907 3 Q14739 1 +High frequency sensorineural hearing impairment 0.851201126158696 1.2652014785244603 0.2057991126002076 1.0 0.7314452361521542 3 Q13510 1 +Erectile dysfunction 0.5867697188398927 1.264109326666276 0.2061907894920474 1.0 0.7314452361521542 10 O00170,Q9BZH6,P07686 3 +Impotence 0.5867697188398927 1.264109326666276 0.2061907894920474 1.0 0.7314452361521542 10 O00170,Q9BZH6,P07686 3 +Abnormal myeloid leukocyte morphology 0.4081865268448774 1.2631387860662528 0.2065393071957832 1.0 0.7314452361521542 103 Q14126,P01889,Q13510,Q9BXW9,O15118,P61916,Q14739,P49459,P16278,P38571,P02786,P10644 12 +Slurred speech 0.6019481202911645 1.2619786029086375 0.2069564858753909 1.0 0.7314452361521542 9 Q69YN2,Q8N0X7,P16278,O75787 4 +Resting tremor 0.5084832348628914 1.2613441067133435 0.2071848965609102 1.0 0.7314452361521542 22 P07602,P02792 2 +Absent hypoplastic paranasal sinuses 0.8496172480095723 1.259522546462019 0.2078416517548742 1.0 0.7314452361521542 3 P04066 1 +Abnormality of the wrist 0.481575035293426 1.2578837314954026 0.2084338080398924 1.0 0.7314452361521542 30 Q15643,Q13510,P11047,O75844,P16278 5 +Atrioventricular canal defect 0.5605960158252998 1.255873137278387 0.2091619693717294 1.0 0.7314452361521542 12 P19022,Q9UBM7 2 +Abnormal oral frenulum morphology 0.5274363475988424 1.255627913015279 0.2092509062699563 1.0 0.7314452361521542 17 O43924,Q69YQ0,Q96PY6,Q2M1P5,P11274,O75844 6 +Abnormal morphology of the limbic system 0.5690879075894197 1.2556026421308957 0.2092600729640028 1.0 0.7314452361521542 11 Q01105,Q96PY6 2 +Visual agnosia 0.8481426448737002 1.254237067794385 0.2097558504203411 1.0 0.7314452361521542 3 P49768,Q9NUM4 2 +Anomic aphasia 0.8481426448737002 1.254237067794385 0.2097558504203411 1.0 0.7314452361521542 3 P49768,Q9NUM4 2 +Abnormal thoracic spine morphology 0.4927312163404028 1.2533889167262189 0.2100642030165456 1.0 0.7314452361521542 26 P04062,O00459,O00754,O75844,O95831 5 +Pituitary adenoma 0.5684918928152574 1.2527852034102045 0.210283887974084 1.0 0.7316292253286999 11 O75874,O00170,P10644 3 +Abnormal larynx physiology 0.5317543545491346 1.2506118068600705 0.2110761408576946 1.0 0.7328575247966318 16 Q9UQN3,Q13510,Q9H0U9,Q96PY6,Q99700,Q14203 6 +Gray matter heterotopia 0.4804025140195705 1.249990475038111 0.2113030268055789 1.0 0.7329623427943707 30 P19022,P07942,O43505,Q06787,Q9UBM7,P43034,P35606,Q96PU5 8 +Vertigo 0.502687049122516 1.2461178665919463 0.2127211264351332 1.0 0.7351217073097409 23 O00170,P01889,P06280 3 +Abnormality of hair texture 0.4366046046214971 1.246048878228147 0.2127464512467569 1.0 0.7351217073097409 53 Q02487,P51798,P04080,P15586,P54802,P62266,Q9Y6K9,O75844,Q08J23 9 +Toe walking 0.4909224366366947 1.2418765796658435 0.2142821024179717 1.0 0.7377535315046793 26 Q8ND04,Q99720,P06753,P07602,O95831 5 +Shoulder girdle muscle weakness 0.5574486685618176 1.2405873666242606 0.214758221285682 1.0 0.7377535315046793 12 P06753,P07602 2 +Bilateral cryptorchidism 0.5647953094214507 1.2353071058260732 0.2167162301596117 1.0 0.7422450379166493 11 P37268,P78318,O43924,Q2M1P5 4 +Rapidly progressive 0.5559759882419159 1.2334329834794195 0.2174142655244666 1.0 0.7425222244641521 12 Q14108,P49768 2 +Abnormal pupillary function 0.6299219740406693 1.2324422088243163 0.2177839419981495 1.0 0.7425222244641521 7 P07602 1 +Abnormal circulating igm level 0.5331320756173202 1.2320837029376857 0.2179178184982568 1.0 0.7425222244641521 15 Q15904,P13051 2 +Abnormal vascular morphology 0.4783552295609388 1.2290543250931454 0.2190514385088477 1.0 0.7441663849391643 230 P42892,Q9BXW9,P01130,Q7LGA3,P61916,Q9UBM7,P05067,P07602,P06865,Q15643,P10619,P10253,P49459,P16278,P17900,P34913,P19022,Q13510,O15118,P07686,O00459,P38571,Q15392,Q96PU5,Q8ND04,P10644,P01889,P04062,Q9ULC3,Q96PY6,Q15056,O75844 32 +Abnormal csf protein level 0.5549854077515812 1.228620019336084 0.2192143060189555 1.0 0.7441663849391643 12 P07602 1 +Hirsutism 0.4252366782178185 1.2252192202981005 0.220492634600933 1.0 0.7473127695812755 64 P15586,P54802,O00170,P49459,P16278,P53634 6 +Dysuria 0.6099027670767967 1.220934059472873 0.2221109874574389 1.0 0.7505727467442829 8 P01889,O00170,Q8N0X7,P07741 4 +Peg shaped maxillary lateral incisors 0.8276886512180663 1.220590325337765 0.2222411712160403 1.0 0.7505727467442829 2 Q96PY6 1 +Ventricular preexcitation 0.6096934922265762 1.2200387767535863 0.2224501755067016 1.0 0.7507286303703475 8 P13473 1 +Abnormality of the knee 0.3937632165858873 1.2171450662854513 0.2235490266936934 1.0 0.7514267478114288 91 Q7LGA3,Q15643,P51798,Q86XL3,O00754,P16278,Q04721,P06753,Q9NX62,Q13510,Q8N0X7,P11047,O00459,Q96PU5,Q8TD16,O95831,O75312,Q9ULC3,Q15056,Q9Y619 20 +Fetal ultrasound soft marker 0.5089335479958851 1.215530892161039 0.2241636738578472 1.0 0.751559662897946 19 Q15643,Q9NUM4 2 +Abnormality of bone mineral density 0.432513926111258 1.213891488597774 0.2247891635411965 1.0 0.752334271583132 142 Q9BXW9,P06280,O00170,P07602,Q14108,Q15643,P51798,P54802,Q14739,O00754,P16278,Q15043,Q13510,Q32P28,Q15392,O95831,P10644,Q9BZH6,P04062,Q15056,O75844 21 +Bilateral polymicrogyria 0.5910711591609027 1.2138494671948254 0.2248052125479209 1.0 0.752334271583132 9 Q01105 1 +Abnormal thrombocyte morphology 0.4204391302030008 1.2122636424105364 0.2254114765352026 1.0 0.752334271583132 125 Q6YHK3,Q14108,P01889,Q13510,P04062,Q9BXW9,P51798,P28070,Q14739,Q8NB90,Q15904,P38571,P02786,P07602,P10644 15 +Spastic diplegia 0.4936975038624508 1.2121068621160125 0.2254714773134107 1.0 0.752334271583132 24 P07602 1 +Lack of skin elasticity 0.5244383582846971 1.2114502457928782 0.2257228922954239 1.0 0.752334271583132 16 O00170,O75844 2 +Eunuchoid habitus 0.8358995200965873 1.2104216616805723 0.2261171340112642 1.0 0.7525842582038593 3 Q9BZH6 1 +Abnormality of primary teeth 0.5286667764622596 1.208659508526812 0.2267936839180149 1.0 0.7525842582038593 15 P04080,P53634,Q9ULC3,O75844 4 +Myopathic facies 0.6628042595144973 1.2057634807791586 0.2279087002659405 1.0 0.7525842582038593 5 P06753 1 +Aplasia hypoplasia of the eyebrow 0.4380506706625776 1.197042934569695 0.231289820528427 1.0 0.7573152721191644 43 Q14574,Q02487,Q07954 3 +Abnormal circulating ceruloplasmin concentration 0.7086391648318298 1.1961910731601593 0.2316220036481127 1.0 0.7573152721191644 4 O00400 1 +Short ribs 0.5482589255526709 1.1959260602421278 0.2317254144241058 1.0 0.7573152721191644 12 Q15643,Q14739,Q96PY6 3 +Abnormal shape of the frontal region 0.4097744488233985 1.1953764844344708 0.2319399690542842 1.0 0.7573152721191644 113 Q9BXW9,P15586,O00170,Q9Y6K9,Q4J6C6,P04066,Q15643,P51798,Q14739,O00754,P16278,P19022,Q06787,P63241,O00459,Q15392,Q8ND04,P29372,O43924,P43034 20 +Coronal craniosynostosis 0.6336275428517311 1.1944955137624218 0.232284194557846 1.0 0.7573152721191644 6 Q9NX62 1 +Developmental regression 0.4226420332339888 1.1896595310643376 0.2341802374062291 1.0 0.7615873893801722 131 O14773,Q13510,O75503,P06280,P07686,P16278,P17900,P07602 8 +Gonosomal inheritance 0.4169412094629012 1.1894609375431708 0.2342583336531636 1.0 0.7615873893801722 68 O15347,P78318,Q0IIM8,P13473,Q06787,P06280,Q15904,P49459,Q9Y6K9,O95831 10 +Abnormal thalamic size 0.8193701723113529 1.1880547677167443 0.2348118331910791 1.0 0.7623116556414611 2 P11166 1 +Mask like facies 0.5371229514412489 1.1833410530359192 0.2366740088859393 1.0 0.7635179712835413 13 P04062,P19525,Q06787,O75787,Q99700,Q14203 6 +Conical incisor 0.8279346210995547 1.1819916546467384 0.2372090122098602 1.0 0.7646535703237237 3 Q9Y6K9,Q96PY6 2 +Deposits immunoreactive to beta amyloid protein 0.8275952047233659 1.1807816041612968 0.237689493768741 1.0 0.7646535703237237 3 P05067 1 +Finger agnosia 0.8275952047233659 1.1807816041612968 0.237689493768741 1.0 0.7646535703237237 3 P05067 1 +Neoplasm of the gastrointestinal tract 0.3866765679475521 1.1787341861971403 0.2385040383155432 1.0 0.7647949361263028 87 P42892,P11717 2 +Abnormality of the peripheral nervous system 0.3960149706794306 1.177823405282791 0.2388670157178329 1.0 0.7647949361263028 98 P42892,Q99720,P04062,Q9NSV4,Q9UBM7,P06280,Q10713,P07686,Q92734,P07602,O95831 11 +Abnormal right ventricle morphology 0.5827922492349825 1.177203642248262 0.2391142352674888 1.0 0.7647949361263028 9 P11047,P06753,P19022 3 +Abnormal electroretinogram 0.46377610003895 1.1756694963102905 0.239726972568262 1.0 0.7647949361263028 33 O14773,P50897 2 +Death in infancy 0.4151702979682822 1.1730209674990857 0.240787397510358 1.0 0.7652874689517247 68 Q15643,P04062,Q9BZH6,Q15904,P38571,P16278,Q9Y6N7,P07602 8 +Mitral valve calcification 0.7018146760533241 1.1703529114630935 0.2418589770301444 1.0 0.7652874689517247 4 P04062 1 +Cardiac valve calcification 0.7018146760533241 1.1703529114630935 0.2418589770301444 1.0 0.7652874689517247 4 P04062 1 +Increased susceptibility to fractures 0.4250164459410697 1.169276488167878 0.2422922528443809 1.0 0.7652874689517247 57 Q14108,Q15643,P51798,P04062,Q9BZH6,O75874,Q14739,Q32P28,P10644 9 +Polyneuropathy 0.4980938226912205 1.1670060873996846 0.2432079112141121 1.0 0.7652874689517247 20 P07602 1 +Tonic seizure 0.4707839250740482 1.1650745680616703 0.2439888102564309 1.0 0.7652874689517247 28 P07602,Q01105,P43034,P67870 4 +Transposition of the great arteries 0.6521780315039725 1.1638996392951386 0.2444646858019394 1.0 0.7652874689517247 5 O75844 1 +Cardiac conduction abnormality 0.4618906442470354 1.1624652160873212 0.2450465459358992 1.0 0.7652874689517247 33 Q07954,P06280 2 +Abnormal rib ossification 0.6996955947148648 1.1623383180717946 0.2450980676550602 1.0 0.7652874689517247 4 Q5F1R6,Q14739 2 +Dysmetria 0.4200070569237915 1.1608141821348128 0.245717474252314 1.0 0.7652874689517247 62 O14773,Q8IV08,Q8N0X7,O75503,Q06787,Q15056,Q10713,O15121,Q9NUM4 9 +Entropion 0.5636586229603346 1.1584207594014315 0.246692371537416 1.0 0.7668589567009361 10 P01889 1 +Aortic valve calcification 0.8205749851574354 1.1557830527978008 0.2477699066870258 1.0 0.7676204770344013 3 P04062 1 +Agenesis of incisor 0.6496892076565173 1.154106134778941 0.2484566585612904 1.0 0.7686258667505582 5 Q96PY6 1 +Abnormal circulating igg level 0.5134867142257991 1.1527387196398775 0.2490176437491891 1.0 0.7686258667505582 16 Q15904,P13051 2 +Abnormal social behavior 0.4104277132501513 1.1508036435260145 0.2498130255173922 1.0 0.7686258667505582 70 O94992,O96000,Q8NB90,Q5KU26,Q15056,P05067,P49768,P07602,P11166 9 +Pancreatic fibrosis 0.6965288062555859 1.1503693481428323 0.2499917792238353 1.0 0.7686258667505582 4 Q96PY6 1 +Malabsorption 0.4245972624803586 1.1489044687451369 0.2505953747778935 1.0 0.7686258667505582 54 P01889,Q14739,P38571,P06280 4 +Vestibular dysfunction 0.4681524099825611 1.1476462896057582 0.2511146122431751 1.0 0.7686841716075944 28 O00170,P01889,Q15043,P06280 4 +Craniofacial osteosclerosis 0.8181620833820766 1.147204380829954 0.2512971614332158 1.0 0.7687325243577471 3 Q15043 1 +Glioblastoma multiforme 0.5924596260435843 1.1463270599300115 0.2516598504197547 1.0 0.7693315055935471 8 O75874,P43246,P60866,P42771 4 +Porencephalic cyst 0.6211821072760454 1.144185392082444 0.2525467599374948 1.0 0.7710202406038751 6 P07942 1 +Abnormal carotid artery morphology 0.5160722892044036 1.142516220241537 0.253239507751918 1.0 0.771602201411991 15 P01130,Q15056,O75844 3 +Generalized osteosclerosis 0.816611035049063 1.1416937421471534 0.2535813429046207 1.0 0.7721334153172402 3 Q15392 1 +Congenital hepatic fibrosis 0.620332840278967 1.1407554289662083 0.253971713157842 1.0 0.77238894032311 6 Q96HP0,Q10713,Q96J42 3 +Hypothalamic hamartoma 0.8162520235195603 1.1404186681061863 0.2541119190927474 1.0 0.77238894032311 3 O43924 1 +Abnormal arachnoid mater morphology 0.5596934668815394 1.140284241790537 0.2541679007527457 1.0 0.77238894032311 10 Q15904 1 +Prominent antihelix 0.8065953654188966 1.138306416667825 0.2549925555485424 1.0 0.7732875160605656 2 P98175 1 +Decreased circulating igg level 0.5363642682122739 1.1380827882195927 0.2550859144417563 1.0 0.7732875160605656 12 Q15904 1 +Patchy alopecia 0.692666825434513 1.135787003720674 0.256045717510275 1.0 0.7736221092756818 4 O75844 1 +Oculogyric crisis 0.5435413267320374 1.1347447003617364 0.2564823023388061 1.0 0.7736221092756818 11 Q01105 1 +Optic disc coloboma 0.6443102663591662 1.1329580754804618 0.2572318596482406 1.0 0.7746412928129544 5 Q10713 1 +Short stepped shuffling gait 0.8130757800891536 1.1291452173414416 0.2588365791542961 1.0 0.7773528533558991 3 Q14203,P04062 2 +Epiphyseal stippling 0.5340819897651766 1.1269833012046262 0.259749541303127 1.0 0.7790796261596717 12 Q14739,Q9UBM7 2 +Decreased circulating iga level 0.5708540006278987 1.1243709614782942 0.2608556857393926 1.0 0.7802134769568457 9 Q15904,P13051 2 +Episodic pain 0.5334802935636214 1.124057143785939 0.260988784611331 1.0 0.7802134769568457 12 P07686 1 +Proptosis 0.4210735077953169 1.1237297154472836 0.2611277061975221 1.0 0.7802134769568457 55 O94992,Q9UBM7,Q5KU26,O00754,Q32P28,O75844,Q15043,Q9NX62 8 +Dysarthria 0.4419282814351136 1.1236935920879043 0.2611430357796991 1.0 0.7802134769568457 171 O14773,P15586,O75503,P61916,P07602,Q14108,Q9H173,Q8IV08,O00754,O15118,P02792,Q10713,P07686,Q9NUM4,P11166,Q9BZH6,P04062,P04080,Q96PY6,Q15056 20 +Limited hip movement 0.5251019703808371 1.1232157638729978 0.2613458691341694 1.0 0.780313767298265 13 P06753,Q7LGA3,O75844 3 +Contractures of the joints of the upper limbs 0.4048476620893585 1.1214474270868118 0.26209745787793 1.0 0.7805357111222593 72 P42892,Q8IZA0,O75844,Q15392,Q99720 5 +Impaired proprioception 0.4383311062042783 1.1209595936653256 0.2623050622045542 1.0 0.7806496686655874 40 P54802,Q8IV08,O14773 3 +Nephrotic syndrome 0.4679288650349931 1.1193835238271856 0.2629765568864475 1.0 0.7821431788687244 27 Q14108,P11047,P06280 3 +Aplasia hypoplasia of the retina 0.6873726172797934 1.1158241670326037 0.2644974069852006 1.0 0.7841370072037138 4 Q9Y6K9 1 +Left ventricular hypertrophy 0.4741616389507878 1.1120024392978256 0.2661371015399307 1.0 0.7870226570663151 25 P10253,P06280 2 +Bilateral sensorineural hearing impairment 0.4737248278658832 1.109251143395762 0.2673218551440639 1.0 0.7873407410707183 25 P07602 1 +Nephropathy 0.4854718478720157 1.107750927607755 0.2679693984229832 1.0 0.7876877202107968 21 Q14108,Q10713,P43034,P06280 4 +Bruising susceptibility 0.4559573534653895 1.1074782545284807 0.2680872088960391 1.0 0.7876877202107968 32 Q14108,P04062,Q9BXW9,O00170,P10644 5 +Elevated circulating aspartate aminotransferase concentration 0.5298620226548089 1.1064622269719195 0.2685265046346234 1.0 0.7880279523286192 12 Q15904 1 +Oral pharyngeal dysphagia 0.5090776372268613 1.1057530310901402 0.2688334296216714 1.0 0.7880279523286192 15 Q01105,Q13510 2 +Hydrocephalus 0.3963936341375393 1.1056298573016476 0.2688867611741687 1.0 0.7880279523286192 77 O75312,P04062,Q9BXW9,P51798,P07942,O43505,Q9UBM7,Q14118,Q10713,O00459,O00754,Q15392,Q08J23,P10644,P11166 15 +Abnormality of the lymph nodes 0.4445564351576646 1.1045431687813152 0.2693575882357897 1.0 0.7880313624411789 37 P01889,Q13510,P28070,P13051,P10644 5 +Emg abnormality 0.3989834127889581 1.1031934191977766 0.2699431785480606 1.0 0.7880313624411789 75 Q14126,O14773,Q13510,P13473,P11047,Q92734,P49768,P07602 8 +Personality changes 0.4993783574791737 1.101997189657043 0.2704628933988644 1.0 0.7880313624411789 17 P04062,Q9NR50,Q13144,P49768,Q14203,Q9NUM4 6 +Atelectasis 0.5512539165172656 1.101695648227548 0.2705940095133448 1.0 0.7880313624411789 10 Q13510 1 +Skeletal dysplasia 0.422351328576972 1.0993801864803752 0.2716022694068103 1.0 0.7894618297385849 44 Q15643,Q9BZH6,Q14739,P10619,P16278,O95831 6 +Jaundice 0.4162438153177081 1.0988412094959157 0.2718373337685076 1.0 0.7895815148663815 58 O15118,P61916,Q14739,Q15904,P38571,P10644 6 +Abnormal left ventricle morphology 0.4587408406555697 1.0937724891828708 0.2740547726912492 1.0 0.7935882550921225 29 P10253,P06280 2 +Intracranial hemorrhage 0.4676645056261818 1.0932465101625928 0.2742855812145228 1.0 0.7936080423384612 26 Q6YHK3,P05067,P04062 3 +Abnormality of vitamin d metabolism 0.5493452185334816 1.0929724309364457 0.2744059044441447 1.0 0.7936080423384612 10 Q01968,P62913,Q7Z2Z2,P46783,Q5F1R6 5 +Male sexual dysfunction 0.5269368113009493 1.0922400609256 0.2747275982928698 1.0 0.7940351522399587 12 O00170,Q9BZH6,P07686 3 +Skin pit 0.4972043127077418 1.0900717234336172 0.2756815510165766 1.0 0.7953015958613382 17 P49459,Q07954 2 +Aplasia hypoplasia of the skin 0.4128169573456021 1.088761054701437 0.2762592699030999 1.0 0.7954748496272894 61 Q07954,Q15126,O00170,O75844,Q15392,Q96PU5,P53634 7 +Hypoplasia of the iris 0.631652167625741 1.0833070859853688 0.2786721411262225 1.0 0.7977526653880528 5 Q7LGA3 1 +Abnormal circulating iga level 0.5083291736346538 1.081185920983354 0.2796144194376275 1.0 0.7982894034988347 14 Q15904,P13051 2 +Shuffling gait 0.524498361873533 1.0803869410116045 0.2799699086400744 1.0 0.7982894034988347 12 P04062 1 +Kyphosis 0.4245940799999348 1.0803027898641566 0.2800073677782246 1.0 0.7982894034988347 149 O15347,Q7LGA3,Q9UBM7,Q5KU26,O00170,Q9Y6K9,Q14108,P04066,Q9H173,Q14739,Q9HC07,O00754,P16278,P06753,O94992,Q8N0X7,O00459,Q32P28,O95831,P10644,P01889,P04062,Q9ULC3,Q15056,O75844 25 +Supernumerary spleens 0.5314091433592499 1.07736178335856 0.281318670420692 1.0 0.8005426361971545 11 Q15904,Q9ULC3 2 +Thick vermilion border 0.3920290483341727 1.076736656816604 0.2815979309757423 1.0 0.8008429745824629 78 Q96PZ0,P04066,P15586,P06280,Q15056,O00170,Q9Y619,Q8ND04,Q01105,Q08J23,P11166 11 +Raynaud phenomenon 0.6038256644555873 1.074201964127616 0.2827321722798332 1.0 0.8014526400136338 6 Q14739,O75844 2 +Absence of pubertal development 0.6292617796785827 1.073952242097319 0.2828440868995356 1.0 0.8014526400136338 5 O75844 1 +Dysgenesis of the cerebellar vermis 0.7890671420083237 1.0705585901632948 0.2843679513175163 1.0 0.8014526400136338 2 Q10713 1 +Acute hepatic failure 0.5145000762945083 1.0701905702920391 0.2845335379822713 1.0 0.8014526400136338 13 P38571 1 +Leukopenia 0.4178190129632396 1.067164764513319 0.2858974405864249 1.0 0.8014526400136338 47 Q14108,P04062,Q15904,P38571,P10644 5 +Abnormality on pulmonary function testing 0.478403107515399 1.0659668690184003 0.2864386189282786 1.0 0.8014526400136338 21 P16278 1 +Depression 0.3960302994928614 1.0654316679174267 0.2866806324863089 1.0 0.8014526400136338 111 P01889,Q9BZH6,P04062,Q96PY6,P06280,O00170,O00754,P50897,P07602,Q9NUM4,P10644,P11166 12 +Aplasia hypoplasia involving the skeletal musculature 0.5430523984769298 1.0642278227509496 0.2872255058897912 1.0 0.8014526400136338 10 Q9H173,O43505,Q14118 3 +Bundle branch block 0.501023272890405 1.0634155926582998 0.28759352468229 1.0 0.8014526400136338 15 P06280 1 +Mortality aging 0.399621536123067 1.0623302307239644 0.2880857950192217 1.0 0.8014526400136338 116 Q15643,P04062,Q9BZH6,Q14739,Q15056,Q15904,P05067,P07686,P16278,P38571,O75844,Q9Y6N7,P07602,O43678 14 +Preaxial polydactyly 0.4821327232246131 1.061979946738714 0.2882447889680271 1.0 0.8014526400136338 19 O43924,Q96J42,Q9BXW9,Q9ULC3,Q96PY6,Q2M1P5 6 +Abnormality of circulating adrenocorticotropin level 0.5275119780086898 1.0589447449395506 0.2896249448002144 1.0 0.8043198768246917 11 Q13423,O00170 2 +Gingival fibromatosis 0.7923317078321581 1.0558833764903428 0.291021499768656 1.0 0.8059208222349139 3 Q15392 1 +Hepatomegaly 0.4394372617537493 1.055215979756704 0.2913265574140766 1.0 0.8059208222349139 178 Q14108,P04066,Q13510,O15118,P15586,P54802,P61916,Q15904,P10253,O43772,O00754,P16278,P07686,P38571,P07602 15 +Dystrophic toenail 0.5866231665501664 1.0536344172589636 0.292050325464972 1.0 0.8059208222349139 7 O75844 1 +Abnormal pupillary light reflex 0.6703047597559351 1.0517211301035054 0.2929275135923954 1.0 0.8059208222349139 4 P07602 1 +Slow pupillary light response 0.6703047597559351 1.0517211301035054 0.2929275135923954 1.0 0.8059208222349139 4 P07602 1 +Asymmetry of the ears 0.7837195484254335 1.050026739965934 0.2937058188431605 1.0 0.8059411062076463 2 Q9H2M9 1 +Branchial cyst 0.7837195484254333 1.0500267399659329 0.2937058188431611 1.0 0.8059411062076463 2 P27635 1 +Abnormal cortical bone morphology 0.4943383430904614 1.0499564881477697 0.2937381184042573 1.0 0.8059411062076463 16 P35606,O00754,P51798 3 +Preaxial foot polydactyly 0.5968783985739025 1.0462745147751744 0.2954343083066066 1.0 0.806820783420761 6 Q9ULC3,Q96PY6,Q2M1P5 3 +Pectus carinatum 0.4338380404201091 1.0439842010903095 0.2964926992412147 1.0 0.8079776812415804 38 Q15643,Q9H173,Q96PY6,Q2M1P5,Q9Y619,O00754,P16278,Q04721 8 +Increased circulating igm level 0.5842205369206466 1.043753186878629 0.2965995953004658 1.0 0.8079776812415804 7 P13051 1 +Abnormal acetabulum morphology 0.476802425393577 1.043101845098633 0.2969011262523291 1.0 0.8079776812415804 20 Q15643,P16278 2 +Nonimmune hydrops fetalis 0.4521110978017913 1.0411371033119527 0.2978119216410881 1.0 0.8095005653097974 28 P04062,P62913,O96000,Q14739,P10619 5 +Cholestatic liver disease 0.5834746732537408 1.0406870617527264 0.2980208099284045 1.0 0.8095910039893605 7 Q9H9C1,Q04721,Q9UBM7 3 +Metaphyseal widening 0.4733919960275005 1.0363290659152418 0.3000486505456294 1.0 0.8127052168127802 21 Q15643,Q14739,P16278 3 +Urinary urgency 0.550679964829143 1.0352401758184302 0.3005567605444148 1.0 0.8131259777639391 9 P04062 1 +Opportunistic infection 0.7792632204396959 1.032971381192728 0.3016172918033368 1.0 0.8141510276360131 2 Q9Y6K9 1 +Dyslexia 0.5361906043534099 1.032918430958967 0.3016420727119979 1.0 0.8141510276360131 10 P49768,Q9NUM4,P11166 3 +Cardiac diverticulum 0.6651343731160915 1.0323920196022256 0.3018885089264524 1.0 0.8143393950561416 4 P60866,P43246 2 +Elongated superior cerebellar peduncle 0.7768865121806356 1.0238964254545817 0.3058841987713849 1.0 0.8198407885674911 2 Q10713 1 +Migraine 0.4629758242561321 1.02188179451569 0.306836850024438 1.0 0.8209622046504117 24 O00170,P05067,P01889 3 +Hand polydactyly 0.4304611303489816 1.0186282200552073 0.3083795016204931 1.0 0.8239692206108451 38 O43924,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q10713,O00459 7 +Respiratory failure 0.3972775980818993 1.0159042594809975 0.3096749803103524 1.0 0.8239692206108451 69 Q13510,Q8TD16,P61916,Q96PY6,Q14118,Q9Y619,P10253,Q92734,P06753,P07602 10 +Femoral bowing 0.5462115321304727 1.0155442826380536 0.3098464489609149 1.0 0.8239692206108451 9 O00754 1 +Minicore myopathy 0.7792676820550128 1.0101268431944008 0.3124345230823162 1.0 0.8267064672618778 3 P51114 1 +Acute kidney injury 0.6575084959055695 1.0039721100809702 0.315392056876016 1.0 0.8311709189981656 4 P07741 1 +Photophobia 0.4331345932760561 1.0028828146953894 0.3159174052660147 1.0 0.8311709189981656 36 P04439,P07602,P01889 3 +Rigidity 0.4032068386968581 1.002638377563121 0.3160353719669186 1.0 0.8311709189981656 61 P04062,P02792,P16278,Q15392,P07602 5 +Abnormal pyramidal sign 0.4036249151854787 1.0016620928192306 0.3165068207120713 1.0 0.8311709189981656 129 P01889,O14773,P04066,Q99720,P02792,O00400,O00754,O95831,P17900,P07602,Q9NUM4,Q15043,P11166 13 +Abnormality of the calf 0.3986525055156502 1.000210900992306 0.317208454893765 1.0 0.8318913114057426 66 O75312,Q15643,P51798,Q7LGA3,Q8N0X7,Q9ULC3,Q96PY6,Q2M1P5,Q15056,Q9Y619,O00754,Q04721,P16278,Q32P28,O95831,Q9NX62 16 +Urinary incontinence 0.4093743480540938 0.9970099951391004 0.318759658394212 1.0 0.8321888122001302 47 P07602,P07686,Q99720,O94898 4 +Soft tissue sarcoma 0.4381377443984954 0.995450558099176 0.319517179521525 1.0 0.8321888122001302 33 Q07954,Q15392 2 +Lower limb hyperreflexia 0.4640393943891122 0.9949829169738864 0.3197445729415891 1.0 0.832310830751398 22 O00400,Q14739,P02792 3 +Erythema 0.4613824279846714 0.994553962539836 0.3199532477755094 1.0 0.8323840136823353 23 O00170,Q9Y6K9,Q07954,P01889 4 +Gastrointestinal hemorrhage 0.4420542260492858 0.9900933245501942 0.3221285058897485 1.0 0.8360102603929462 30 Q6YHK3,P01889 2 +Unilateral renal agenesis 0.4692224183185365 0.9878880468644492 0.3232074801062532 1.0 0.8376787272274032 19 O75179,Q7LGA3,Q9UBM7,P35606,P10644 5 +Coloboma 0.4057186283676975 0.9865510493398756 0.323862777489621 1.0 0.8376787272274032 54 O15347,O43924,P78318,Q9P273,O43505,Q9UBM7,Q14118,Q2M1P5,Q10713,Q9NP58,Q04721 11 +Abnormal corneal epithelium morphology 0.4738147862140685 0.9865208232616028 0.3238776020774383 1.0 0.8376787272274032 18 P01889,Q14739,O75844 3 +Chest pain 0.4824739373372501 0.9862973113481504 0.3239872387519436 1.0 0.8376787272274032 16 P01889,P19022 2 +Thick eyebrow 0.4081438260196539 0.9840015995892344 0.3251147264100762 1.0 0.8382432263704985 45 P15586,P04066 2 +Recurrent fever 0.4969870864124316 0.9827319132693724 0.3257393996600735 1.0 0.8384470309508312 13 Q13510 1 +Absent hand 0.7696879643387823 0.9767965855591424 0.3286698667873398 1.0 0.8428672841283638 3 Q96HP0,Q9Y6K9 2 +Sclerocornea 0.4878651808608492 0.975923867734296 0.3291021933689924 1.0 0.8428672841283638 14 Q9P273,Q9UBM7 2 +Bowing of the legs 0.4042458058596745 0.9738315009449732 0.3301402094209436 1.0 0.8441188937496117 54 O75312,Q15643,P51798,Q7LGA3,Q8N0X7,Q9ULC3,Q2M1P5,Q15056,Q9Y619,O00754,Q04721,P16278,Q32P28,Q9NX62 14 +Abnormal gallbladder morphology 0.4392423554611758 0.9709473673956543 0.3315744887996525 1.0 0.8450894950702704 30 P07602,P04062 2 +Myositis 0.5352914663222464 0.9675156858587032 0.3332863036549085 1.0 0.8450894950702704 9 P01889,P28070 2 +Cystic hygroma 0.5352104361600224 0.9671599411060046 0.3334640843803234 1.0 0.8450894950702704 9 Q15643 1 +Reduction of neutrophil motility 0.6473909395342559 0.9664490773484852 0.3338195163824213 1.0 0.8450894950702704 4 Q7Z2Z2,Q5F1R6 2 +Proximal femoral epiphysiolysis 0.6473909395342559 0.9664490773484852 0.3338195163824213 1.0 0.8450894950702704 4 Q7Z2Z2,Q5F1R6 2 +Abnormality of vitamin e metabolism 0.6473909395342559 0.9664490773484852 0.3338195163824213 1.0 0.8450894950702704 4 Q7Z2Z2,Q5F1R6 2 +Deformed rib cage 0.6473909395342559 0.9664490773484852 0.3338195163824213 1.0 0.8450894950702704 4 Q7Z2Z2,Q5F1R6 2 +Abnormal heart valve morphology 0.3778102720794404 0.962563181424513 0.3357667819880336 1.0 0.8477365280414754 80 P01889,P04062,Q9BXW9,P51798,P06280,Q15056,O75844,P16278,Q96PU5,P06753,P10644 11 +Abnormal cell proliferation 0.7654596770125052 0.9621514828263316 0.3359735162796415 1.0 0.8477365280414754 3 P17812 1 +Abnormality of neutrophil physiology 0.5996110541593087 0.9586751673772907 0.3377224121972957 1.0 0.8477365280414754 5 Q7Z2Z2,Q5F1R6 2 +Immunodeficiency 0.3982727518258318 0.9582810983626534 0.337921032413349 1.0 0.8477365280414754 61 P02786,P13051,Q8NB90,O00754 4 +Abnormality of the plantar skin of foot 0.4136875624890523 0.9524516871855914 0.3408679568069011 1.0 0.850098136878171 41 Q14126,P53634,Q02487 3 +Abnormality of the gastric mucosa 0.4797648217020441 0.951813575712426 0.3411915358310402 1.0 0.850098136878171 15 P04062,Q14739 2 +Thoracic hypoplasia 0.4334971404814575 0.9511597155578172 0.3415233047585029 1.0 0.850098136878171 32 Q15643,P04062,P51798,Q14739,Q96PY6 5 +Upper limb spasticity 0.5459793435450224 0.948507587025767 0.3428711122251013 1.0 0.850098136878171 8 Q99720 1 +Diminished movement 0.4556441906012733 0.9445392919483582 0.3448941329833008 1.0 0.850098136878171 22 O95831,P06753,P04062,P13473 4 +Global brain atrophy 0.4595521235805836 0.9426266489564046 0.3458719040402367 1.0 0.850098136878171 20 P07602 1 +Generalized hyperpigmentation 0.4888326705576264 0.9421217142339732 0.3461303284559516 1.0 0.8501123144283095 13 Q13423 1 +Stomach cancer 0.5156341463243131 0.939454428245414 0.3474974794218386 1.0 0.8502653962917379 10 P60866,P42771,P10644 3 +Focal dystonia 0.4496415326506817 0.9390996049684855 0.347679607077116 1.0 0.8502653962917379 24 Q99720,P02792 2 +Abnormal aortic valve morphology 0.4173345427875994 0.9386126865202996 0.3479296368160489 1.0 0.8502653962917379 39 P01889,P04062,P06280,Q15056,O75844 5 +Cerebral hamartoma 0.6393251361325185 0.9367034718601828 0.348911109866715 1.0 0.8505976819066928 4 O43924 1 +Reticulocytosis 0.4799025649013194 0.9350759521683494 0.349749158664955 1.0 0.8518310637014262 14 Q8NBF2,P51798,P11166 3 +Neoplasm of the skin 0.4017140382488303 0.9309567242979486 0.3518759502538182 1.0 0.8536544518250514 45 P53634,Q15126,P10644,Q07954 4 +Upper limb asymmetry 0.7513368983957265 0.9273937795205842 0.3537221191746287 1.0 0.8545403642312897 2 P07437 1 +Abnormal blood monovalent inorganic cation concentration 0.4548930992373462 0.9269202024223429 0.353967967142657 1.0 0.8545403642312897 21 Q13423,O00170,P11166 3 +Difficulty walking 0.3756674316427097 0.9260292313626396 0.3544307893081058 1.0 0.8545403642312897 79 P07602,O14773,P02792,Q13510 4 +Abnormal anatomic location of the heart 0.4849811330154727 0.9229765856520072 0.356019407279275 1.0 0.8564008110181405 13 P19022,Q10713,O75844 3 +Pain 0.4293720598596686 0.9226578827629404 0.356185520915445 1.0 0.8564008110181405 182 P42892,P01130,Q13423,P06280,O00170,P07602,Q14108,P51798,Q07954,O75874,Q14739,Q15043,P19022,Q13510,P28070,P02792,P07686,P10644,P01889,P04062,Q96PY6,Q15056,O75844 23 +Restlessness 0.4069289916277231 0.9220867384233136 0.3564833337649133 1.0 0.8564008110181405 42 P42892,P04062,P05067,Q9NUM4,P10644 5 +Disinhibition 0.3960670596556507 0.9208915118290324 0.3571070706366626 1.0 0.8564008110181405 58 P19022,P04062,Q06787,P02792,P05067,P49768,Q14203,Q9NUM4 8 +Abnormal meningeal morphology 0.4536111905964791 0.9193449842870008 0.3579151556262308 1.0 0.8564008110181405 21 Q15904,Q10713 2 +Neonatal hyperbilirubinemia 0.6345493076568126 0.9191684792983174 0.3580074553656351 1.0 0.8564008110181405 4 P49459 1 +Abnormal lower limb bone morphology 0.4240240472996535 0.9178892335591056 0.3586768588029201 1.0 0.8564008110181405 173 Q96PZ0,Q9BXW9,Q7LGA3,Q9UBM7,P06280,Q14118,P07602,P04066,Q15643,P51798,Q9H173,Q14739,P49459,O00754,P16278,Q9NX62,Q13510,Q8N0X7,Q06787,Q10713,Q32P28,Q15392,O95831,P10644,O43924,P04062,Q9ULC3,O43505,Q96PY6,Q9Y619,O75844,Q08J23 32 +Abnormal platelet volume 0.5239426654298959 0.9178023812485072 0.3587223353744098 1.0 0.8564008110181405 9 Q15477,P35579,O15143,Q14739 4 +Striae distensae 0.5107589763519078 0.917389080347762 0.3589387927361436 1.0 0.8564740344273406 10 O00170 1 +Sensorimotor neuropathy 0.4274011858012733 0.9086505593957688 0.3635346094057579 1.0 0.8619601785994616 32 O94992,Q5KU26,P07602,O95831 4 +Microtia third degree 0.745989304812839 0.9074696458465494 0.3641584941673352 1.0 0.8622274472869139 2 Q9Y619 1 +Muscle fibrillation 0.4635119985585421 0.9054267544997688 0.3652393472036315 1.0 0.8622274472869139 17 P04792,Q13510,Q9H0U9,Q92734,Q8NCE2,O95831 6 +Eeg with focal spike waves 0.6294944454741 0.9006767337508823 0.3677602226331089 1.0 0.8622274472869139 4 P11166 1 +Abnormal epiphysis morphology of the phalanges of the hand 0.4935537743344365 0.8992165161776037 0.3685373446647908 1.0 0.8622274472869139 11 Q15643,Q9ULC3,P10644 3 +Supernumerary tooth 0.5593015827454391 0.8965743057081778 0.3699461138041449 1.0 0.8622274472869139 6 Q9UBM7 1 +Postural tremor 0.4497180927645613 0.8963498092052927 0.3700659644879562 1.0 0.8622274472869139 21 O14773 1 +Gangrene 0.5056260092025406 0.8942103979484703 0.3712093299295276 1.0 0.8634081790994562 10 P01889 1 +Hip contracture 0.5055096265620296 0.8936855405575568 0.3714901639298302 1.0 0.8636256458479664 10 P06753,Q7LGA3 2 +Abnormality of the larynx 0.3964803148139342 0.892688852480934 0.3720238217322023 1.0 0.8640473044491344 49 Q9UQN3,Q13510,Q14739,Q9UBM7,P27635,P07737,Q9H0U9,Q2M1P5,Q96PY6,P42771,Q14203,Q99700,P07602 13 +Polyhydramnios 0.3959710953939886 0.890459399548394 0.3732192597106956 1.0 0.8640714076255348 50 Q15643,Q70HW3,P51798,P62913,P04062,Q14739,Q9UBM7,P27635,Q2M1P5,P43034,O75844,P06753 12 +Bradykinesia 0.4327069431310538 0.88924101733291 0.3738735631004575 1.0 0.8640714076255348 27 P04062,Q06787,P02792,P06753,Q15043 5 +Abnormal femoral head morphology 0.4518090690847952 0.8880877776256676 0.3744935366576414 1.0 0.8640714076255348 19 Q9H173,Q7LGA3,P16278 3 +Widely spaced teeth 0.4255034085123901 0.885786280380403 0.3757327042291742 1.0 0.8640714076255348 31 O00754,P16278 2 +Chorioretinal hypopigmentation 0.7394533571004209 0.8832636838342496 0.3770938204506187 1.0 0.8656680282534729 2 Q9Y619 1 +Neurodegeneration 0.4270160553935058 0.8802915922266511 0.3787013661634453 1.0 0.868131923427888 29 P17900,Q9Y3Z3,P02792,Q96PY6 4 +Generalized myoclonic seizure 0.3982526906555737 0.8764258707375036 0.3807985592214862 1.0 0.870342765498786 43 Q13510,P04062,Q8NB90,P16278,P07602 5 +Abnormal lung lobation 0.4862702946481041 0.8652363937252151 0.3869090539513136 1.0 0.8795121985776901 11 Q9UBM7 1 +Adrenocortical carcinoma 0.6195922613149468 0.8646710795957654 0.3872193471704759 1.0 0.8795676199517184 4 P10644 1 +Unusual infection 0.4403735365624033 0.8632994027557503 0.3879728724901008 1.0 0.879599933305701 217 Q9BXW9,O94898,P15586,Q13423,P78318,Q9UBM7,Q9Y6K9,P02786,P07602,P04066,Q15643,P51798,P78536,O75179,P54802,Q14739,P10253,P49459,O00754,P16278,P49768,P06753,P53634,Q13510,Q8NBF2,P28070,P11047,Q15904,P10644,P11166,P01889,P04062,Q15056,P13051 34 +Abnormality of dermal melanosomes 0.73380867498515 0.8624949903177521 0.388415188674124 1.0 0.879599933305701 2 Q9Y4I1 1 +Cerebral cortical atrophy 0.373985381204474 0.8619703120111318 0.3887038549879364 1.0 0.879599933305701 107 O94992,O43924,P04062,Q7LGA3,O75503,P43034,Q96PY6,Q06787,Q8NB90,Q5KU26,Q15056,Q9Y6K9,P05067,O00754,Q9Y619,P49768,Q8TD16,Q9NUM4 18 +Micropenis 0.3845455371582176 0.8613478699333286 0.3890464780933458 1.0 0.879599933305701 65 O75312,P42892,P19022,Q9BZH6,Q9BXW9,O43505,Q9UBM7,Q96PY6,P49459,Q9Y3Z3,Q10713 11 +Posterior pharyngeal cleft 0.7332144979203858 0.8603164678694836 0.3896146176046169 1.0 0.8800212577938676 2 P29372 1 +Abnormal natural killer cell physiology 0.7340267459138194 0.8547716675177199 0.3926775660901775 1.0 0.8840290150178506 3 Q15833,Q9Y6K9 2 +Anencephaly 0.4608129897134574 0.8528118165915219 0.3937636699442763 1.0 0.8841941151695636 15 Q9Y3Z3,Q96J42,O43505 3 +Abnormal tricuspid valve physiology 0.4401651645960421 0.8516708818516536 0.3943967862398265 1.0 0.8845089805177969 22 Q15904,P19022,P10644 3 +Thin ribs 0.4698802215660506 0.8482089403492707 0.3963216191076084 1.0 0.8845089805177969 13 O95831,Q9Y619,Q32P28,O75844 4 +Sound sensitivity 0.5078381406455913 0.8477288060099405 0.3965890199936124 1.0 0.8845089805177969 9 P17900 1 +Hyperacusis 0.5078381406455913 0.8477288060099405 0.3965890199936124 1.0 0.8845089805177969 9 P17900 1 +Reduced factor xiii activity 0.7296494355317931 0.847276892730634 0.3968408031953321 1.0 0.8845089805177969 2 Q02750 1 +Pectus excavatum of inferior sternum 0.7296494355317931 0.847276892730634 0.3968408031953321 1.0 0.8845089805177969 2 Q02750 1 +Reduced factor xii activity 0.7296494355317931 0.847276892730634 0.3968408031953321 1.0 0.8845089805177969 2 Q02750 1 +Amegakaryocytic thrombocytopenia 0.7296494355317931 0.847276892730634 0.3968408031953321 1.0 0.8845089805177969 2 Q02750 1 +Abnormality of facial musculature 0.3607343888503206 0.8472156463323137 0.3968749340079271 1.0 0.8845089805177969 84 Q13510,P04062,P02792,P10253,O00754,Q15043 6 +Biconcave vertebral bodies 0.535656272552983 0.8461290214065699 0.3974807724698299 1.0 0.8845089805177969 7 O00170 1 +Lateral clavicle hook 0.5697110878827585 0.8444487624134787 0.3984186835820724 1.0 0.8845089805177969 5 Q96PY6 1 +Pneumonia 0.3891963715972618 0.8435668940675534 0.398911470471774 1.0 0.8845089805177969 54 Q13510,P04062,P78318,O00754,P16278,Q92734,P06753 7 +Hyposmia 0.4521336680248431 0.843366654402629 0.3990234152301695 1.0 0.8845089805177969 17 P04062,Q15043 2 +Abnormality of upper limb joint 0.3784672146888653 0.842623850281808 0.3994388478854962 1.0 0.8845089805177969 115 P42892,Q8IZA0,Q13510,Q15643,Q7LGA3,Q9H173,Q9ULC3,P11047,Q15056,P16278,Q15392,O75844,O95831,P10644 14 +Palpitations 0.4405994781665917 0.8425716587148108 0.3994680471666059 1.0 0.8845089805177969 21 Q14126,Q02487 2 +Congenital malformation of the right heart 0.4925592985119433 0.8354989196227849 0.4034368549835951 1.0 0.8870976596913814 10 P01889 1 +Limitation of joint mobility 0.3650283095527675 0.8352794059640887 0.403560409881788 1.0 0.8870976596913814 99 P01889,P15586,P54802,Q7LGA3,O75874,P11047,Q15056,O00754,P16278,O75844,P06753 11 +X linked recessive inheritance 0.3891684654761556 0.8348789477672323 0.4037858691273037 1.0 0.8870976596913814 51 P78318,P00492,P27635,P06280,O75787,Q15904,P49459,Q9Y6K9,P98175,P29372,O95831 11 +Aplasia hypoplasia of the breasts 0.504314356882881 0.8324867977853906 0.4051342271113334 1.0 0.8876527010428625 9 Q9Y6K9,Q9BZH6 2 +Amyotrophic lateral sclerosis 0.4499849177423711 0.8316784529218829 0.4055904660542988 1.0 0.8876527010428625 17 Q9UQN3,Q99720,Q96PY6,Q99700,P49768,Q14203 6 +Abnormal diaphysis morphology 0.3737069488223424 0.8314887303485329 0.4056975920719794 1.0 0.8876527010428625 73 O75312,Q15643,Q96J42,P51798,Q7LGA3,Q8N0X7,Q9ULC3,Q14739,Q2M1P5,Q9HC07,O00170,Q15056,Q9Y619,O00754,Q04721,P16278,Q32P28,Q9NX62 18 +Malignant hyperthermia 0.6079072532699081 0.8225954611660143 0.4107380806169396 1.0 0.8901059503181193 4 P36871,P50570,Q8NCE2 3 +Clonus 0.4130856823782083 0.8186663988572771 0.4129767724110613 1.0 0.8901059503181193 33 Q99720,Q8N0X7,O00400,P07602,Q15043 5 +Brain neoplasm 0.6058263971462458 0.8151537736776975 0.4149842943678345 1.0 0.8901059503181193 4 Q04206,P28340,P06400 3 +Neoplasm of the adrenal cortex 0.5382292905691887 0.8141044150229668 0.415585136847282 1.0 0.8901059503181193 6 O75874,P10644 2 +Decreased calvarial ossification 0.6049228855990403 0.8119276464957911 0.4168331496111752 1.0 0.8902875925838759 4 O75844 1 +Leukoencephalopathy 0.3600125376024992 0.8078707004035354 0.4191650197314513 1.0 0.891717000905395 96 P07942,O00584,O75503,P17900,P07602 5 +Echolalia 0.4610644624656721 0.8048379491441747 0.4209131994376258 1.0 0.8930027602915962 13 P49768,Q9UQN3,P49459,Q9NUM4 4 +Omphalocele 0.4670203410507749 0.8032053239109787 0.4218560688413459 1.0 0.8930027602915962 12 Q9ULC3,Q14739 2 +Abnormality of the nail 0.3845204491178158 0.8031289273247124 0.4219002195043593 1.0 0.8930027602915962 128 P42892,Q02487,P04066,P04080,Q14739,P02792,Q15056,Q14574,O00170,P49459,Q9Y6K9,O75844,P53634,P10321,P10644 15 +Dyscalculia 0.46638784634775 0.8001979194974774 0.4235961350322383 1.0 0.8946895547164166 12 P49768,Q9NUM4,Q06787 3 +Lumbar hyperlordosis 0.4402885865989047 0.7992617822109519 0.424138634365488 1.0 0.8952743152128663 18 P06753,Q96J02,P04066,Q14118 4 +Facial hypertrichosis 0.3817330234928024 0.7985111956272769 0.4245738988428109 1.0 0.8954645574688793 59 P49459,P15586,O00170,P54802 4 +Abnormality of tibia morphology 0.4529528462621124 0.7977669602646468 0.4250057379049692 1.0 0.8954645574688793 14 O95831,Q32P28 2 +Stroke 0.4080104293513653 0.793506584421719 0.4274827345981695 1.0 0.8968412747748643 34 P05067,P06280 2 +Muscular hypotonia of the trunk 0.3611900494937867 0.7918081867993487 0.4284725280112178 1.0 0.8968412747748643 80 P19022,Q8NBF2,P43034,Q8NB90,Q9Y3Z3,O00459,O00754,Q96PU5,P17900,P07602,Q08J23,Q15043 12 +Generalized onset seizure 0.3706253054624495 0.7912564369631337 0.4287943638797491 1.0 0.8968412747748643 111 Q14108,Q13510,P04062,O75503,P02792,Q8NB90,P16278,P07602 8 +Abnormal pleura morphology 0.4316519224193879 0.7899619202429473 0.4295500075277441 1.0 0.8968412747748643 21 P01889 1 +Diastasis recti 0.59837411555443 0.788639079799734 0.430322983167958 1.0 0.8976420599114419 4 Q96JJ3,Q8NCH0 2 +Preaxial hand polydactyly 0.4569455487491112 0.7846607829217691 0.4326524819893653 1.0 0.8999857715471693 13 Q96J42,Q9BXW9,O96028,Q96PY6,Q2M1P5 5 +Abnormal head movements 0.4676898741793089 0.7792557309067027 0.4358290865914693 1.0 0.9015015589768894 11 Q99720,Q06787,P11166 3 +Cessation of head growth 0.5187536082394913 0.7787690398085858 0.436115778491936 1.0 0.9015015589768894 7 Q05086,Q13144,Q9NR50 3 +Mandibular aplasia 0.5954036399754743 0.7781325000985949 0.4364909047450127 1.0 0.9015015589768894 4 O75419,Q9Y619 2 +Dysdiadochokinesis 0.4434138802784364 0.7780969162515022 0.4365118805409658 1.0 0.9015015589768894 16 P18887,O75503,Q06787 3 +Abnormal abdomen morphology 0.4352840898009318 0.7755075547980513 0.438039803060354 1.0 0.9015015589768894 224 Q14108,P01889,P04066,Q13510,O15118,P15586,P54802,P61916,P10619,Q15904,P10253,O43772,O00754,P16278,P07686,P38571,Q15392,P07602 18 +Tongue fasciculations 0.4606093859651015 0.7727893412300838 0.4396470624760202 1.0 0.901990635520451 12 Q13510,O95831 2 +Acute phase response 0.4222276131015759 0.7693629918900285 0.441677851874557 1.0 0.9041451585886802 24 P28070,P02792,P01889 3 +Abnormal sweat gland morphology 0.707568146611099 0.7668794205407278 0.4431532104064928 1.0 0.9043542717901424 3 O75844 1 +Flat face 0.4132524774767805 0.7622993224583406 0.4458813781946991 1.0 0.9072258122820476 27 Q15643,O00754 2 +Episodic tachypnea 0.4760367978708947 0.7620173545494409 0.4460496464133245 1.0 0.9072258122820476 10 O43924 1 +Calvarial hyperostosis 0.5462920208272017 0.7570473402281783 0.4490215011256364 1.0 0.9098746940208516 5 Q15043 1 +Axial muscle weakness 0.5891956081613552 0.7562956743089088 0.4494719410528704 1.0 0.9098746940208516 4 P11047 1 +Iris coloboma 0.3910255898029812 0.7552396967417255 0.4501051740580304 1.0 0.9098746940208516 40 P78318,Q9P273,O43505,Q9UBM7,Q10713 5 +Plantar hyperkeratosis 0.4019696572809032 0.7504246007526264 0.4529990191145248 1.0 0.9098746940208516 34 P53634,Q02487 2 +Abnormality of the chin 0.3570687871214456 0.7493276556088069 0.4536597429635549 1.0 0.9098746940208516 80 P19022,Q07954,Q7LGA3,P67870,Q06787,P11047,O00170,Q15056,O00754,P16278,O75844,P11233,P10644 13 +Keratoconjunctivitis 0.4726320511251712 0.7470025254428743 0.4550620364062938 1.0 0.9098746940208516 10 P01889 1 +Stomatocytosis 0.7013271079669041 0.7465482030315241 0.455336324509187 1.0 0.9098746940208516 3 P11166 1 +Abnormal blood ion concentration 0.3678382177661685 0.7451936792559841 0.4561546433956502 1.0 0.9098746940208516 70 P11166,P51798,Q13423,Q8NB90,O00170,Q15904,Q15056,Q9NP58,P10644,Q15043,Q4J6C6 11 +Azoospermia 0.448560582988636 0.7437833920513625 0.457007529209553 1.0 0.9108537439066318 13 Q13423,Q9BZH6,P04062 3 +Pancytopenia 0.3991468895593645 0.7413948791344958 0.4584540485131061 1.0 0.9117658169307244 35 Q14108,P04062,O00754,P10644 4 +Poor motor coordination 0.4477464194850171 0.7398296784688426 0.4594033482968971 1.0 0.9118859550907816 13 O75503,Q10713 2 +Irregular menstruation 0.5187494768029989 0.7392399730012441 0.4597612920881309 1.0 0.9118859550907816 6 O00170,P10644 2 +Ulnar deviation of the hand or of fingers of the hand 0.4589079556001867 0.7390569485976642 0.4598724173355157 1.0 0.9118859550907816 11 Q9H2M9,P11274,Q14739,Q9UBM7 4 +Abnormality of the diencephalon 0.3987418148018277 0.7384719320386699 0.4602277172792064 1.0 0.9118859550907816 35 P19022,O43924,Q9BZH6,P02792,P11166 5 +Neoplasm of the tongue 0.4703348343586362 0.7368995594295047 0.4611834319856605 1.0 0.9130392367040452 10 O43924,Q96PY6 2 +Abnormal temper tantrums 0.4943278095614831 0.7337541989539278 0.4630985593909624 1.0 0.9134571751409496 8 P04062 1 +Large earlobe 0.4943199943573316 0.7337224035777398 0.4631179413672384 1.0 0.9134571751409496 8 Q04721,Q15392 2 +Weakness of muscles of respiration 0.3963360639170513 0.7332549659066178 0.4634029364235559 1.0 0.9134571751409496 36 P06753,P10253,Q13510,O95831 4 +Ulnar deviation of finger 0.4936210101176276 0.7308797429829781 0.4648526101693422 1.0 0.9134571751409496 8 Q9H2M9,P11274,Q9UBM7 3 +Abnormality of the distal phalanges of the toes 0.5388966908011732 0.7299254289730229 0.4654357677421192 1.0 0.9141398304401918 5 O75844 1 +Abnormal proximal phalanx morphology of the hand 0.5388199779780412 0.729645433289708 0.4656069432589647 1.0 0.9141398304401918 5 Q9ULC3 1 +Lower limb spasticity 0.3463816789258598 0.7260443270319407 0.4678115968622929 1.0 0.9148818550201334 86 P04062,Q99720,P07942,O00400,O00754,O43678,P07602,O95831,P11166 9 +Posterior fossa cyst 0.694295900178259 0.7212656780408835 0.4707460695729755 1.0 0.9148818550201334 2 Q9UHX1 1 +Mandibular prognathia 0.3921859103856241 0.7160292404368672 0.4739732939123389 1.0 0.9148818550201334 37 P67870,P11047,O00170,O00754,P16278,P10644 6 +Death in adulthood 0.4343065408692583 0.7159818393356381 0.4740025627134978 1.0 0.9148818550201334 15 P05067 1 +Generalized hyperreflexia 0.5348010650303621 0.715016901121687 0.4745985998807707 1.0 0.9148818550201334 5 P11166 1 +Hypertrichosis 0.3596353354125125 0.7148281206461925 0.4747152566915269 1.0 0.9148818550201334 106 P15586,P54802,Q8NB90,O00170,P49459,O00754,P16278,P53634 8 +Babinski sign 0.3495477318079394 0.712172493266199 0.4763579679565726 1.0 0.9150818441328534 94 O14773,Q99720,P02792,O00400,O00754,P07602,O95831,Q15043,P11166 9 +Aplasia hypoplasia of the tongue 0.5017190004365464 0.7119875983740296 0.4764724556302824 1.0 0.9150818441328534 7 Q9UBM7,Q96PY6 2 +Generalized muscle weakness 0.3963712816559626 0.7105713669178821 0.4773498916787762 1.0 0.9150818441328534 34 Q96PY6,P11047,P10253,Q9NP58,P06753,O95831 6 +Abnormal eyebrow morphology 0.400375579396621 0.7105198176132818 0.4773818460775618 1.0 0.9150818441328534 165 O94992,P19022,Q02487,P04066,O43924,Q07954,P15586,P54802,Q7LGA3,Q8NB90,Q5KU26,Q14574,O00170,P49459,O00754,O75844,Q10713 17 +Hypoplasia of the brainstem 0.4022676906025825 0.709766400436027 0.4778490080869237 1.0 0.9150818441328534 28 P07942,O43505,P43034,P07437,Q10713,Q13409 6 +Keratitis 0.4412344689524348 0.7083146984777553 0.4787498513329695 1.0 0.9150818441328534 13 P01889,Q14739 2 +Hypertrophic cardiomyopathy 0.3636445208397341 0.7069447640564842 0.4796008042837107 1.0 0.9150818441328534 112 P01889,Q9BXW9,P15586,P54802,Q13423,P13473,P06280,Q15056,O00170,P10253,O43678,P16278 12 +Dicarboxylic aciduria 0.4097511825853013 0.7063530310854936 0.479968622110037 1.0 0.9150818441328534 25 Q9NPF0 1 +Vascular tortuosity 0.5744810215723896 0.7052440064062343 0.4806583996141773 1.0 0.9150818441328534 4 P05067 1 +Abnormal spermatogenesis 0.4344435598459014 0.7048157285136777 0.4809249190985618 1.0 0.9150818441328534 14 Q13423,Q9BZH6,P04062 3 +Osteopetrosis 0.6880869538774635 0.7039902739938951 0.4814388305651669 1.0 0.9150818441328534 3 Q15392 1 +Wormian bones 0.4179752870579092 0.7022110452882429 0.4825475584083385 1.0 0.9154503062808398 20 Q32P28,O95831,Q04721,O75844 4 +Abnormal morphology of the radius 0.4328898192104067 0.6970823833148502 0.4857512383367501 1.0 0.917143311085502 14 Q15643,Q32P28 2 +Neoplasm of the male external genitalia 0.4612272280884011 0.6970821711588365 0.4857513711001657 1.0 0.917143311085502 10 Q13423 1 +Abnormal superior cerebellar peduncle morphology 0.6851792795883066 0.6947549071758744 0.487208911774478 1.0 0.9175470259250644 3 Q10713 1 +Aplasia hypoplasia involving the metacarpal bones 0.4051584193898448 0.6927234402248407 0.4884831260136799 1.0 0.918092933415687 26 Q15643,Q9H173,Q14739,Q32P28,P10644,Q9NX62 6 +Abnormal bleeding 0.3591095203839174 0.6917943777218167 0.4890664679035825 1.0 0.918092933415687 108 Q14108,P01889,Q6YHK3,P04062,Q9BXW9,Q14739,O00170,Q9Y6K9,P05067,O75844,Q96PU5,P10644,P11117 13 +Abnormal brain positron emission tomography 0.4839396635625884 0.6917387907002019 0.4891013819035366 1.0 0.918092933415687 8 P49768,Q9NUM4 2 +Amaurosis fugax 0.470901090004538 0.6901627815252 0.4900918257683624 1.0 0.9184546088373046 9 P01889 1 +Abnormality of periauricular region 0.4070495013584158 0.6895033574072861 0.4905065611621353 1.0 0.9184546088373046 25 P49459,Q07954 2 +Spastic tetraparesis 0.4045778296811794 0.6890374392113491 0.4907997074836303 1.0 0.918464430680527 26 P07602 1 +Obsessive compulsive behavior 0.3721504494688032 0.6872124186235887 0.4919488797137821 1.0 0.9186513239154268 44 O75503,Q15056,P49459,P49768,Q9NUM4 5 +Fractures of the long bones 0.6826343514820556 0.6867060288901164 0.4922679970151979 1.0 0.9186513239154268 3 P51798 1 +Zonular cataract 0.4307359478054393 0.6863824199225692 0.4924719874400296 1.0 0.9186513239154268 14 P02792 1 +Heterotropia 0.3708980627408711 0.6849294815482869 0.4933884212179695 1.0 0.9197414564556572 54 O94992,O43924,P04062,Q9P273,Q5KU26 5 +Bilateral tonic clonic seizure 0.3469479158359176 0.6838207976207136 0.4940883320151461 1.0 0.9202475261313708 94 Q13510,P04062,P22466,P04080,Q14739,Q96PY6,Q8NB90,P07686,P07602,Q01105,Q9NUM4,P11166 12 +Long palpebral fissure 0.4035281335343167 0.6823767556639506 0.4950007498219353 1.0 0.9202475261313708 26 O94992,Q5KU26,O00459 3 +Trichorrhexis nodosa 0.680661479164516 0.6804888640036554 0.4961949706110808 1.0 0.9205863791064378 3 P18074 1 +Hypoplastic labia minora 0.5249402115534352 0.6794747928248251 0.4968370740166632 1.0 0.9205863791064378 5 Q9H2M9,Q9Y619 2 +Clitoral hypoplasia 0.5249402115534352 0.6794747928248251 0.4968370740166632 1.0 0.9205863791064378 5 Q9H2M9,Q9Y619 2 +Decreased fertility in females 0.4931956632163853 0.6790717330298794 0.497092411845248 1.0 0.9206894409829623 7 O00170,Q96RD7,Q15645 3 +Aplasia hypoplasia of toe 0.3887227194221611 0.6776796329631953 0.4979748427981625 1.0 0.9212134932983664 36 Q9H2M9,Q96PZ0,Q8IWS0,Q13510,Q7LGA3,Q9UBM7,Q96PY6,Q04721,P10644,Q9NX62 10 +Cerebral white matter hypoplasia 0.5017468286975661 0.6752660580596568 0.4995067442935794 1.0 0.9219272831260152 6 O43776,P11166 2 +Abnormal bone structure 0.4077362673222877 0.6739945575032147 0.5003147738253311 1.0 0.9219272831260152 184 Q9BXW9,Q9UBM7,P06280,O00170,Q9Y6K9,P07602,Q14108,Q15643,P51798,O75874,P54802,Q14739,O00754,P16278,P53634,Q15043,Q13510,Q32P28,Q15392,O95831,P10644,Q9BZH6,P04062,Q15056,P35606,O75844 26 +Abnormality of vitamin a metabolism 0.5228610679045234 0.6720479033080108 0.5015532006374976 1.0 0.9221421186853634 5 Q7Z2Z2,Q5F1R6 2 +Spastic tetraplegia 0.3778175906893461 0.6707615716857385 0.5023724317161777 1.0 0.9221421186853634 41 P04066 1 +Abnormal elasticity of skin 0.3641982680632015 0.6666868346608301 0.5049721899294477 1.0 0.9242037512649902 64 P04062,Q15056,Q15904,O00170,O00754,O75844,P10644 7 +Anterior rib cupping 0.5191624131355321 0.6588967654068558 0.5099620631085924 1.0 0.925196816580327 5 Q5F1R6,O95831 2 +Highly arched eyebrow 0.3638839335664349 0.6580760803398699 0.5104892451328169 1.0 0.925788914265258 63 O94992,O43924,Q7LGA3,Q8NB90,Q5KU26,O00754 6 +Abnormal uvea morphology 0.3541985723646238 0.6556717471916388 0.5120353510047075 1.0 0.9273656903948614 106 P01889,Q9BXW9,P78318,Q7LGA3,Q9P273,O43505,Q9UBM7,Q14118,P11047,Q15056,Q10713,P29317,P04439,P10644 14 +Abnormality of the cervical spine 0.3596295952831483 0.6548479129634818 0.5125656787692205 1.0 0.9273656903948614 113 P04066,Q15643,P15586,Q7LGA3,Q9ULC3,Q9UBM7,P49459,O00754,P16278,O95831,P11166 11 +Sensory axonal neuropathy 0.422187657789186 0.6544140659908876 0.5128450746352691 1.0 0.9275071769590392 15 Q8IV08 1 +Pulmonary hypoplasia 0.3922943657673501 0.6521625745712312 0.5142963004102652 1.0 0.9283108633090535 30 Q15643,Q14739,Q9UBM7,Q96PY6,O75844 5 +Abnormal greater sciatic notch morphology 0.5584982846742835 0.651057082078307 0.5150096396815067 1.0 0.9287104772621616 4 Q5F1R6 1 +Reduced forced vital capacity 0.6709479819308622 0.6501747811636098 0.5155793290554875 1.0 0.929117372454448 3 P06753 1 +Dysphonia 0.3890208140384003 0.6495782211032257 0.5159647048045326 1.0 0.929117372454448 33 Q13510,Q9H173,P02792,Q15056,Q14203 5 +Male hypogonadism 0.4733688720764124 0.6495420024088827 0.5159881067669252 1.0 0.929117372454448 8 O00170 1 +Nail dystrophy 0.388978904206947 0.649285394776257 0.5161539242637401 1.0 0.929117372454448 33 P49459,P53634,O75844 3 +Colon cancer 0.4286797241438159 0.6481658766476674 0.5168776697348063 1.0 0.9297744665424812 13 Q15645,P43246,P42771,P52701,P10644 5 +Medullary nephrocalcinosis 0.6726084373143266 0.6474732427231716 0.5173257064384955 1.0 0.9297744665424812 2 O14656 1 +Partial albinism 0.6720142602495611 0.6454949269229283 0.5186065047869957 1.0 0.9307663300004272 2 Q9Y4I1 1 +Microglossia 0.5152468524850902 0.6450618791954019 0.5188870863559865 1.0 0.9307663300004272 5 Q9UBM7 1 +Periventricular heterotopia 0.4278462482125293 0.644204546385685 0.5194428031637166 1.0 0.931263931171237 13 Q96PU5,P19022,Q9UBM7 3 +Pace of progression 0.39951977189927 0.6440106777214761 0.5195685099723257 1.0 0.931263931171237 174 Q14108,O14773,Q13510,P04062,P07942,P15586,O00584,P54802,Q8IV08,P02792,P35606,Q10713,O00400,Q99720,O95831,Q15043 16 +Neonatal death 0.4220329459113043 0.6434075085562505 0.5199597125928861 1.0 0.9316029051897416 14 P04062,Q14739 2 +Abnormality of epiphysis morphology 0.3612763700261471 0.6398111916234188 0.5222953557583616 1.0 0.9346978222228444 64 Q15643,P51798,Q9H173,Q7LGA3,Q9ULC3,Q14739,Q9UBM7,Q96PY6,P16278,O95831,P10644 11 +Gowers sign 0.4109508310803373 0.6380537967672819 0.5234386613658855 1.0 0.9360171562826732 18 P06753,Q13510,Q14118 3 +Abnormal upper limb bone morphology 0.3475506245716872 0.6361269935082694 0.5246936528121653 1.0 0.9368077999473594 100 O43924,Q15643,Q9BXW9,Q7LGA3,Q9H173,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q15056,Q32P28,O75844,P16278,P53634,P10644,Q9NX62 16 +Paraplegia 0.3636462077646881 0.6300650447788069 0.5286520285190586 1.0 0.9402337389941592 57 Q9BZH6,P04062,P07942,O00400,O00754,O43678,O95831,P11166 8 +Stomatitis 0.4295891752160568 0.6282568681723646 0.5298356819085348 1.0 0.9414493291330244 12 P01889 1 +Progressive 0.3586315302428827 0.627226976688382 0.530510462359614 1.0 0.9414493291330244 115 Q13510,P04062,P07942,P15586,P54802,P02792,O00400,Q99720,O95831,Q15043 10 +Small earlobe 0.5101375963516454 0.6271501520892523 0.5305608149864636 1.0 0.9414493291330244 5 P10586 1 +Macrocephaly at birth 0.6660724896019085 0.6258478593756066 0.531414736869972 1.0 0.9422392065271428 2 Q8NCE2 1 +Abnormality of bone marrow cell morphology 0.3640797416568889 0.6223813614347707 0.5336911332638543 1.0 0.943802217157111 52 Q14108,P04062,Q9BXW9,Q14739,O00754,P10644 6 +Broad foot 0.466069515202794 0.6207726147735898 0.53474924401706 1.0 0.943802217157111 8 O00170,O95831,P27635 3 +Neoplasm of the peripheral nervous system 0.410666571161229 0.6207668868791522 0.534753013278606 1.0 0.943802217157111 17 Q07954 1 +Cavernous hemangioma 0.4859079596636266 0.6170701925723396 0.5371884283593416 1.0 0.9457726066677756 6 Q02750,P36507,Q8NCE2,Q15437 4 +Branchial anomaly 0.4532076657605233 0.6169238032911409 0.5372849855403401 1.0 0.9457726066677756 9 Q9UHX1,P11274,P27635,O15160 4 +Eeg with generalized slow activity 0.4268534715432427 0.6157712789258885 0.5380454857468036 1.0 0.9463524186542406 12 O75503,Q9NUM4,P11166 3 +Increased head circumference 0.3646108949379212 0.6106393697446445 0.5414383528861939 1.0 0.948339972190484 125 P78318,Q7LGA3,Q14118,P07602,Q15643,P51798,O75179,Q14739,Q9NR50,P49459,O00754,P19022,Q06787,Q10713,P07686,O00459,Q15392,P11166,P07942,O43505,O75844 21 +Cranial hyperostosis 0.41509523218516 0.6094797045786706 0.5422065212133718 1.0 0.9486167306891634 14 O00754,Q15043 2 +Typical absence seizure 0.4149654488601815 0.6088480599906713 0.5426251544449798 1.0 0.9486167306891634 14 Q01105,Q13510,P11166 3 +Abnormality of the spinal cord 0.3480229407786649 0.5992156592488455 0.5490290817344488 1.0 0.9528136127573696 75 Q9BXW9,Q9ULC3,Q15056,Q10713,O00400,P05067,P16278,O00754 8 +Hallux valgus 0.4090067227117608 0.599061647290076 0.5491317759033711 1.0 0.9528136127573696 16 P04062 1 +Foot acroosteolysis 0.4807298684715458 0.5983785998338523 0.5495873416660055 1.0 0.9528136127573696 6 O75844 1 +Osteolysis involving bones of the feet 0.4807298684715458 0.5983785998338523 0.5495873416660055 1.0 0.9528136127573696 6 O75844 1 +Generalized onset motor seizure 0.3594666780501148 0.596444612849309 0.5508782445719547 1.0 0.9536420230855092 58 Q13510,P04062,Q8NB90,P16278,P07602 5 +Abnormal male reproductive system physiology 0.3741360677919618 0.595477546809917 0.5515243034254254 1.0 0.954043916994826 38 Q9BZH6,P04062,Q9BXW9,Q13423,Q15056,O00170,P07686 7 +Recurrent hand flapping 0.6517955460559501 0.5919569429216273 0.5538794212634661 1.0 0.9566819528005168 3 Q06787 1 +Hypoplasia of the frontal lobes 0.4583660252840785 0.5907709573082771 0.5546738969613598 1.0 0.956965756539506 8 P35606,Q9UBM7 2 +Abnormal odontoid tissue morphology 0.360207476326032 0.589416822314271 0.5555816944710794 1.0 0.9571119624483094 44 Q15643,Q9UBM7,Q15056,Q9Y6K9,P16278 5 +Widow s peak 0.5393975771881022 0.5882960743520099 0.5563335800973344 1.0 0.957787140769207 4 Q69YQ0,P29372 2 +Chronic neutropenia 0.4677950923605626 0.5833869115682541 0.5596328667366157 1.0 0.9597870221933774 7 Q7Z2Z2,Q5F1R6,Q9Y3A5 3 +Abnormality of lower limb metaphyses 0.444416847762478 0.5812455058256667 0.5610750021484965 1.0 0.9598128360208472 9 Q15643 1 +Abnormality of the foot musculature 0.6477010170993021 0.5797989692369461 0.5620501927827235 1.0 0.9598128360208472 3 Q8NCE2 1 +Supernumerary nipple 0.418471312929256 0.5778384865141134 0.5633731687386596 1.0 0.9598128360208472 12 P19022,Q7LGA3 2 +Arnold chiari malformation 0.393473148288298 0.5755789628927211 0.5648998038394044 1.0 0.9598128360208472 22 O00754,Q15043 2 +Persistence of primary teeth 0.4742843092835054 0.5753633776498243 0.5650455667646415 1.0 0.9598128360208472 6 O75844 1 +Lower limb hypertonia 0.4171626682893888 0.5719628558583323 0.5673471391295344 1.0 0.9598128360208472 12 O00400 1 +Hypoplastic nipples 0.4214072017292093 0.5719610448533862 0.5673483660659226 1.0 0.9598128360208472 11 P10586,Q9Y6K9 2 +Fetal akinesia sequence 0.4732990790594691 0.5718709974864201 0.5674093737918682 1.0 0.9598128360208472 6 P04062 1 +Cone shaped epiphyses of the phalanges of the hand 0.4315118285706556 0.5703927929274941 0.5684113166574074 1.0 0.9598128360208472 10 Q15643,P10644 2 +Neoplasm of the larynx 0.4928501040985481 0.56782665996319 0.5701526752415744 1.0 0.9598128360208472 5 P43246,P42771 2 +Spastic paraplegia 0.3572896994137098 0.5657486599400086 0.5715646514697084 1.0 0.9598128360208472 53 P04062,P07942,Q8N0X7,O00400,O00754,O43678,Q92734,O95831,P11166 9 +Decreased circulating acth level 0.4713047600811268 0.5648230552760413 0.5721941237307093 1.0 0.9598128360208472 6 O00170 1 +Abnormality of earlobe 0.386860021105313 0.5647392260929686 0.572251149369627 1.0 0.9598128360208472 25 Q8IWS0,P63000,P10586,Q7LGA3,Q04721,P11274,Q15392,P98175 8 +Disseminated intravascular coagulation 0.4624758284786556 0.5638749493497889 0.5728392396085265 1.0 0.9598128360208472 7 P38571 1 +Dry skin 0.3729812867064542 0.5635178253158776 0.5730823255356865 1.0 0.9598128360208472 36 P04066,Q02750,P04080,P37268,P49459,Q9Y3Z3,P42771,Q04721,Q8ND04,P18074,Q08J23,Q15650 12 +Functional abnormality of male internal genitalia 0.3795252508603918 0.5631794297460133 0.5733127085819656 1.0 0.9598128360208472 29 Q9BZH6,P04062,Q13423,Q15056,O00170 5 +Wide mouth 0.3515573800093748 0.5617544580625572 0.5742833249292385 1.0 0.9598128360208472 66 P15586,Q7LGA3,Q9UBM7,P49459,P16278,Q01105,P11166 7 +Tibial torsion 0.645870469399889 0.56101478700336 0.5747874567874598 1.0 0.9598128360208472 2 Q9Y5S9 1 +Limited wrist movement 0.490715408440104 0.5606487265524382 0.5750370271775567 1.0 0.9598128360208472 5 O75844 1 +Excessive salivation 0.3791051025833761 0.5604187397948227 0.575193852304668 1.0 0.9598128360208472 29 P15586 1 +Abnormal fear anxiety related behavior 0.3524703343677889 0.5602643895700314 0.5752991131509106 1.0 0.9598128360208472 115 P19022,Q9BZH6,Q7LGA3,O75503,Q96PY6,P06280,O00170,O00754,P17900,Q9NUM4,P10644,P11166 12 +Renal agenesis 0.3566112061853204 0.5599411850622431 0.5755195555323562 1.0 0.9598128360208472 53 O43924,Q9BZH6,Q9BXW9,P62913,O75179,P60866,Q7LGA3,Q9UBM7,P35606,Q86XL3,Q15392,P10644 12 +Non motor seizure 0.3569355196644926 0.5596457509940482 0.5757210919250357 1.0 0.9598128360208472 49 Q13510,P22466,P04080,Q8NB90,Q01105,P11166 6 +Abnormality of the phalanges of the toes 0.3918370668092937 0.5596040676424161 0.5757495297588564 1.0 0.9598128360208472 21 Q9BXW9,Q7LGA3,Q9ULC3,Q96PY6,P49459,Q04721,O75844 7 +Tetraplegia tetraparesis 0.3566886422751614 0.5584517736521534 0.5765359273532897 1.0 0.9598128360208472 51 Q8NBF2,Q13423,Q96PY6,Q92734,P49768,P17900,P07602,O95831 8 +Mesoaxial polydactyly 0.6401809394374411 0.5577520204327056 0.5770137298683946 1.0 0.9598128360208472 3 O43924 1 +Neoplasm of the parathyroid gland 0.529384076135704 0.5563747432295328 0.5779547011076709 1.0 0.9598128360208472 4 P10644 1 +Abnormality of the parathyroid morphology 0.529384076135704 0.5563747432295328 0.5779547011076709 1.0 0.9598128360208472 4 P10644 1 +Parathyroid adenoma 0.529384076135704 0.5563747432295328 0.5779547011076709 1.0 0.9598128360208472 4 P10644 1 +X linked dominant inheritance 0.3866578784566239 0.5527387562907324 0.5804423107233325 1.0 0.9604590999406184 24 Q9Y6K9,P13473 2 +Abnormal number of permanent teeth 0.6376812707150816 0.5505070744103745 0.5819716259795238 1.0 0.9613852101379268 3 Q9ULC3 1 +Contractures involving the joints of the feet 0.3899754123153621 0.5490589710771939 0.5829649807120738 1.0 0.9613852101379268 21 Q8TD16,Q8IZA0,P63241 3 +Hypoplasia of the radius 0.4259363580442241 0.5472900185744924 0.5841795001604051 1.0 0.9613852101379268 10 Q15643 1 +Genu varum 0.4156734653999386 0.5472472413047769 0.5842088845642095 1.0 0.9613852101379268 11 Q15643,Q9ULC3 2 +Abnormality of hepatobiliary system physiology 0.3310919128273031 0.5457104732529153 0.5852649715461224 1.0 0.9613852101379268 85 P01889,Q13510,O15118,O43772,P38571 5 +Lipoatrophy 0.3891236736942134 0.5442433380015249 0.5862740327134706 1.0 0.9613852101379268 21 Q14126,P49768,P04066 3 +Abnormal liver morphology 0.4225180073387986 0.5427621651432198 0.5872935662527119 1.0 0.9613852101379268 246 P01130,P15586,P61916,P11717,P07602,Q14108,P04066,P54802,P10619,P10253,O43772,O00754,P16278,P53634,Q13510,O15118,Q15904,P07686,P38571 19 +Abnormality of the nasal dorsum 0.3548192919993005 0.542649803593507 0.5873709413933623 1.0 0.9613852101379268 51 O75312,Q9Y3Z3,O00754,P16278,O75844,P10644 6 +Retinal atrophy 0.3790412427381786 0.5421123064953349 0.5877411413917044 1.0 0.9614927827593178 27 P04439,Q7LGA3,P04062 3 +Cone shaped epiphysis 0.4003741904740465 0.538631057961176 0.590141452880647 1.0 0.9643928031831912 14 Q15643,O95831,P10644 3 +Abnormality of the hepatic vasculature 0.4135016542893764 0.5379562058413767 0.590607283552 1.0 0.9648120401044366 11 P38571 1 +Verrucae 0.5229774271425858 0.5363385208143219 0.5917246125975439 1.0 0.9662948863176328 4 Q9Y6K9 1 +Respiratory distress 0.3523299606259959 0.5334953426101684 0.5936907341702962 1.0 0.9670526218579396 58 Q15643,Q13510,P04062,P11047,P10253,P07602 6 +Thick hair 0.432415085927799 0.5334220902216033 0.5937414293282364 1.0 0.9670526218579396 9 Q9H9E3,Q9Y487,Q96PY6,Q9BUK6 4 +Edema of the dorsum of hands 0.6357694592988792 0.5298303974755599 0.5962295275158167 1.0 0.9678582435432836 2 Q9Y5S9 1 +Edema of the dorsum of feet 0.6357694592988792 0.5298303974755599 0.5962295275158167 1.0 0.9678582435432836 2 Q9Y5S9 1 +Abnormal cartilage morphology 0.4076612863415677 0.5297136654771933 0.5963104717247991 1.0 0.9678582435432836 12 Q7LGA3 1 +Tooth malposition 0.3310683606934553 0.5198300423901883 0.6031820382370618 1.0 0.9723470654984387 93 O15347,P51798,Q14739,Q9UBM7,Q15056,O00170,O00754,O75844,P16278,P06753,Q01105,P10644 12 +Broad neck 0.4011255300464184 0.519792071395342 0.6032085060517463 1.0 0.9723470654984387 13 P49459,P11166 2 +Short nail 0.4580907082998084 0.5188846452271084 0.603841185986902 1.0 0.9723470654984387 6 O75844 1 +Posteriorly rotated ears 0.3507466711769954 0.5167334217219209 0.6053422619521336 1.0 0.972994106931928 118 P42892,P19022,O43924,P04062,Q7LGA3,O43505,Q9UBM7,Q14118,Q15056,Q9HC07,P07437,Q10713,Q9Y619,Q08J23,Q15392,Q8ND04,P11233,Q4J6C6 18 +Abnormal enzyme coenzyme activity 0.3967730517855593 0.513111324022259 0.6078734507011401 1.0 0.9740342744985248 191 P61916,P07602,Q9H173,Q14739,P10619,P10253,O43772,O00754,P16278,Q13510,O15118,P28070,P11047,Q15904,P07686,P38571,P01889,P04062,O43505 19 +Dialeptic seizure 0.3496786309173087 0.5053885902201858 0.6132859310799659 1.0 0.977898604082743 56 P19022,Q13510,P22466,P04080,Q8NB90,Q01105,P11166 7 +Intestinal malrotation 0.3699269801049824 0.5030817733317772 0.6149067807940605 1.0 0.9782986844468132 30 O75312,Q8NCH0,Q14739,Q9UBM7,Q96PY6,Q04721,Q15392 7 +Abnormal motor evoked potentials 0.6268568033274002 0.5030524003787562 0.6149274314004902 1.0 0.9782986844468132 2 Q9UNE7 1 +Ureteral duplication 0.4454800702134292 0.5029616521280654 0.614991233736847 1.0 0.9782986844468132 7 O75844 1 +Abnormal sternum morphology 0.3475791896500819 0.4988685550527597 0.6178719877458776 1.0 0.980156520516272 116 P78318,Q7LGA3,Q8NCH0,Q15643,Q9H173,Q14739,O43776,O00754,P16278,Q04721,P98175,P06753,Q9BUK6,Q13510,Q02750,O96028,Q96JJ3,Q06787,Q2M1P5,Q96J02,O95831,Q9H2M9,P04062,O75718,Q96PY6,P07437,Q15056,Q9Y619,Q08J23 29 +Aplasia hypoplasia involving bones of the feet 0.3419471847442925 0.4975858354882568 0.6187759893994347 1.0 0.9809031099957718 70 Q15643,Q13510,Q9H173,Q7LGA3,Q8N0X7,Q9ULC3,Q9UBM7,Q06787,Q96PY6,P49459,Q08J23,P10644,Q9NX62 13 +Nephrolithiasis 0.3798458337610561 0.497312054567359 0.6189690123595879 1.0 0.9809031099957718 22 P07741,P00492,Q15056,O00170,Q4J6C6 5 +Short clavicles 0.4134851954254701 0.496617570604154 0.6194587602212038 1.0 0.9810723616338194 10 O75844 1 +Difficulty standing 0.5098364386881568 0.496255362394735 0.6197142553313844 1.0 0.9810723616338194 4 Q92734 1 +Hoarse voice 0.371455523857616 0.4942658419569351 0.6211184453179484 1.0 0.9826204642813116 27 Q13510,Q8N0X7,Q15056,O00170,P06753 5 +Brittle hair 0.3874871906010148 0.4910005373585636 0.6234260674897296 1.0 0.983859270699366 16 Q02750,P62266,O75844,P18074,Q9Y487 5 +Cns hypomyelination 0.3546799284846849 0.4909524789041967 0.6234600585565941 1.0 0.983859270699366 41 Q8NB90,Q99720,P07686 3 +Hyperostosis 0.3872510434569248 0.4898372018521907 0.6242491034263873 1.0 0.983859270699366 16 O00754,Q15043 2 +Scaling skin 0.4113597398549214 0.488104650573917 0.6254757171694494 1.0 0.9840201251220324 10 P78536,O75844 2 +Hammertoe 0.3827298546487402 0.487786874827155 0.625700809133009 1.0 0.9840201251220324 18 Q8N0X7,Q6UWE0,O14656,Q9UBM7,P49588,Q99720 6 +Specific learning disability 0.3408691161289327 0.487332491050354 0.6260227260797473 1.0 0.9840201251220324 70 Q9H173,Q8N0X7,P62266,O43505,Q06787,Q14118,Q9Y619,Q10713,O00754,P49768,Q9NUM4,P10644,P11166 13 +Selective tooth agenesis 0.4404657246538056 0.485443141624986 0.6273620360453651 1.0 0.9840201251220324 7 Q96PY6 1 +Excessive wrinkling of palmar skin 0.6203208556149821 0.4838761157878696 0.6284737918179439 1.0 0.9840201251220324 2 Q9Y487 1 +Palmoplantar cutis laxa 0.6203208556149821 0.4838761157878696 0.6284737918179439 1.0 0.9840201251220324 2 Q9Y487 1 +Abnormal esophagus morphology 0.3471909482215083 0.4836879975299082 0.6286073125689269 1.0 0.9840201251220324 44 Q15056,P01889,P04062,P38571 4 +Peptic ulcer 0.3970749640940143 0.483572327570908 0.6286894177018363 1.0 0.9840201251220324 12 P04062 1 +Abnormality of the costochondral junction 0.6121058835487018 0.4789481470219705 0.6319755176365098 1.0 0.9853345613982724 3 Q5F1R6 1 +Enlargement of the costochondral junction 0.6121058835487018 0.4789481470219705 0.6319755176365098 1.0 0.9853345613982724 3 Q5F1R6 1 +Proximal femoral metaphyseal irregularity 0.6121058835487018 0.4789481470219705 0.6319755176365098 1.0 0.9853345613982724 3 Q5F1R6 1 +Macrotia 0.3261027574337595 0.4786741589952948 0.6321704520170714 1.0 0.9853345613982724 84 Q7LGA3,Q9P273,O00170,P49459,O00754,P16278,Q8ND04,Q01105,P11166 9 +Localized skin lesion 0.4086220349447569 0.4766423163910404 0.6336168450397879 1.0 0.9853345613982724 224 Q9BXW9,P01130,Q7LGA3,P06280,O00170,P07602,Q8IZA0,Q07954,Q14739,Q14574,P49459,P53634,P34913,Q02487,Q13510,Q92542,Q15126,Q15392,Q96PU5,P10644,P01889,P04062,Q9ULC3,Q15056,O75844 25 +Right ventricular hypertrophy 0.4647753521903853 0.4763588545798855 0.633818742440269 1.0 0.9853345613982724 5 P11047 1 +Torsion dystonia 0.502398927363265 0.4742112844846837 0.6353492471622513 1.0 0.9858498920962566 4 P04350,P11166 2 +Impairment of activities of daily living 0.3453437597513375 0.4721698240114669 0.6368055768124128 1.0 0.9863209623941592 58 P07602,P07686,Q99720,O94898 4 +Thoracic scoliosis 0.3942255746765929 0.4713372526207571 0.6373999170210536 1.0 0.9863209623941592 12 P06753,O00459,O75844 3 +Xerostomia 0.3833786542902241 0.4708394546404518 0.637755387019648 1.0 0.9863209623941592 16 Q9UQN3,Q14739,Q96PY6,Q99700,Q14203 5 +Panniculitis 0.4350651627646621 0.4668256009744019 0.6406246578972175 1.0 0.9863209623941592 7 P28070 1 +Constitutional symptom 0.4164815671536986 0.4665977503515895 0.6407876968265742 1.0 0.9863209623941592 248 Q14126,P42892,O94898,P01130,Q13423,P06280,O00170,P07602,Q4J6C6,Q14108,Q07954,Q14739,O00754,Q15043,P19022,Q02487,Q13510,P28070,P02792,P07686,Q99720,P10644,P11166,P01889,P04062,Q96PY6,O75844 27 +Microcornea 0.3623565596937482 0.4654101729795247 0.6416377504589594 1.0 0.9872997428624176 33 O15347,Q9H2M9,Q96J42,Q9P273,Q9ULC3,O43505,Q14118,P07437 8 +Short nose 0.3342368377259294 0.4648292386080748 0.6420537475462498 1.0 0.9876102022650022 103 O94992,P42892,Q15643,P04062,Q5KU26,O75844,Q15392,P10644,Q9NX62 9 +Adenomatous colonic polyposis 0.6056463595839539 0.4616637248527644 0.6443224885061181 1.0 0.989119770900168 3 P28340,P20585 2 +Abnormality of the antitragus 0.604768196711564 0.4593399488980737 0.6459900642618384 1.0 0.9909507561934554 3 Q9H2M9 1 +Generalized abnormality of skin 0.4090144851883037 0.4588038389605585 0.6463750377166422 1.0 0.9909507561934554 229 Q9BXW9,P61916,Q9UBM7,P06280,O00170,Q9Y6K9,Q14108,Q8IZA0,P04066,P78536,Q07954,Q14739,P10619,O43772,P16278,Q6YHK3,O15118,Q15126,Q15904,P38571,P10644,P11166,P01889,P04062,P04080,Q15056,O75844 27 +Protruding tongue 0.3935723500027503 0.4547065862621803 0.6493203419217646 1.0 0.9921666477491996 11 Q10713 1 +Abnormal renal cortex morphology 0.3434569926503272 0.4479525746591895 0.6541874239206229 1.0 0.9971176831739283 53 Q14108,P06280 2 +Female infertility 0.5997058713669712 0.4460680491467574 0.6555480915607448 1.0 0.9971176831739283 3 Q96RD7 1 +Spinal canal stenosis 0.4287040830995832 0.4452459103858028 0.6561420520155445 1.0 0.9971176831739283 7 O00170 1 +Advanced eruption of teeth 0.3912201713013917 0.4451430153873091 0.6562164046145209 1.0 0.9971176831739283 11 O75844,Q9UBM7 2 +Abnormal retinal morphology 0.4061674810357031 0.4446266183005041 0.6565896079498033 1.0 0.9971176831739283 225 P04439,P01889,O43924,O14773,Q13510,P04062,O75503,Q9P273,O43505,P10619,P07686,O00754,P50897,P16278,P17900,P07602,P06865 17 +Short long bone 0.3585721515783731 0.439733216533441 0.660130341858649 1.0 0.998425484241592 33 Q15643,Q9H173,Q96PY6,P16278,P10644 5 +Frequent falls 0.3497471445165193 0.4392784889901277 0.6604597588426362 1.0 0.9985960932320606 40 P07602,Q13510,P04062 3 +Bifid uvula 0.3552575002018925 0.4369489250606728 0.6621483891812496 1.0 0.9995101748937658 36 P78318,P62266,O43505,Q14118,Q9Y619,Q15392 6 +Myofibrillar myopathy 0.4892984542211528 0.4365947761984395 0.6624052517417753 1.0 0.9995706090113206 4 Q9Y281,Q13642,O95817 3 +Pierre robin sequence 0.4252726291519366 0.433768269573658 0.6644567254963385 1.0 1.0 7 O75179 1 +Broad nasal tip 0.341742489346736 0.433378040847647 0.6647401508670598 1.0 1.0 49 O43924,P10586,Q7LGA3,P16278,O95831 5 +Paraparesis 0.3591558335266582 0.4302277035915061 0.667030011514921 1.0 1.0 28 Q9Y3Z3,Q8N0X7,Q13510,P04062 4 +Dental crowding 0.365742815678077 0.4293985734879706 0.6676331917444194 1.0 1.0 24 O75844,Q01105,Q9UBM7 3 +Abnormality of blood circulation 0.3332927351236665 0.4293239520684152 0.6676874882945592 1.0 1.0 72 Q6YHK3,P01889,P04062,Q14739,P05067,O75844,P10644 7 +Poikilocytosis 0.3766870552560729 0.428706622458089 0.6681367406064564 1.0 1.0 14 O14656,Q9NP58,Q8NBF2,P11166 4 +Ependymoma 0.4304133148073885 0.4275125730482402 0.6690060293662947 1.0 1.0 6 O75874,P42771 2 +Generalized hirsutism 0.3583181784006093 0.4256492325251765 0.6703634601082735 1.0 1.0 29 Q96JJ3,P07437,O00170,P49459,Q04721,P53634 6 +Abnormality of facial soft tissue 0.3468142634343186 0.4256331302735404 0.6703751951872008 1.0 1.0 124 Q13510,P04062,P51798,P28070,Q0IIM8,P02792,Q9UBM7,P11047,O00170,P10253,Q15056,O00754,O75844,Q15043 14 +Waddling gait 0.3582873310611259 0.4254523467201435 0.6705069530431302 1.0 1.0 29 Q13510,Q14118,P11047,P06753,Q4J6C6 5 +Eeg with abnormally slow frequencies 0.3661497694102684 0.4253131243459309 0.6706084273751625 1.0 1.0 23 O75503,Q9NUM4,P11166 3 +Nonprogressive 0.4294015253689465 0.4243112238720495 0.6713388547959227 1.0 1.0 6 Q10713,Q9BUF5 2 +Abnormality of taste sensation 0.5907875185735526 0.4232128294293442 0.6721399872333362 1.0 1.0 3 Q12756,O95163 2 +Increased total bilirubin 0.4830558858501703 0.4192433882240742 0.6750382655533631 1.0 1.0 4 P14314,P08237,Q9UGP8 3 +Myalgia 0.3449746531505177 0.416704351429404 0.6768946711481332 1.0 1.0 41 P01889,P06280 2 +Akinesia 0.3835877872793659 0.4145346757198327 0.6784825775319816 1.0 1.0 11 Q14203,P51114,P04062 3 +Renal cortical microcysts 0.5950683303624575 0.4137140866719387 0.6790835093953551 1.0 1.0 2 Q6PGP7 1 +Congenital bilateral hip dislocation 0.594771241830075 0.4129276917043867 0.6796595918015271 1.0 1.0 2 Q02809 1 +Proximal muscle weakness 0.3333126204018102 0.4094824198861028 0.6821856656050829 1.0 1.0 69 Q13510,P13473,Q14118,P11047,P10253,Q92734,P06753,Q99720 8 +Anal stenosis 0.4792634341082828 0.4088908086072979 0.6826197945456889 1.0 1.0 4 Q69YQ0,Q08J23 2 +Holoprosencephaly 0.3759735847625511 0.4085492423643602 0.6828704863341741 1.0 1.0 13 Q9UBM7 1 +Moderately reduced visual acuity 0.5849071454045878 0.4085214586998002 0.6828908796322921 1.0 1.0 3 P63000 1 +Deep palmar crease 0.3791534469756693 0.408069751886716 0.683222466332783 1.0 1.0 12 Q69YQ0,Q02750,Q96AX1,O00170,P98175,Q9Y487 6 +Impaired temperature sensation 0.423907978432179 0.4071152326446152 0.6839233560819371 1.0 1.0 6 P04792,P07686 2 +Cerebral hypomyelination 0.3668057756501093 0.4062018720281401 0.684594278703055 1.0 1.0 18 Q8NB90,P04350,Q9NR50 3 +Craniofacial dysostosis 0.4409963264912206 0.4045125920825094 0.6858358201074009 1.0 1.0 5 P10644 1 +Abnormality of limb epiphysis morphology 0.353260972178572 0.4039543419346946 0.6862462944581824 1.0 1.0 33 Q15643,Q9H173,Q7LGA3,Q9ULC3,O95831,P10644 6 +Painless fractures due to injury 0.5906120023767178 0.402017594288219 0.6876710778074131 1.0 1.0 2 Q12756 1 +Spina bifida occulta 0.3658876401055352 0.4015862748192136 0.6879885325567718 1.0 1.0 18 Q15056,Q9Y6K9,Q9ULC3 3 +Brachycephaly 0.3333460211248207 0.3986299342229137 0.690165901654989 1.0 1.0 67 P04066,P04062,Q9ULC3,Q96PY6,O00754,P10644 6 +Limb girdle muscle weakness 0.3558671785626368 0.3976649026899654 0.690877211916979 1.0 1.0 27 P06753,P07602,Q14118 3 +Focal motor seizure 0.3628269368324678 0.3970428796839537 0.691335840481837 1.0 1.0 20 Q01105,O75503,P67870 3 +Breast aplasia 0.4743811268053162 0.3957786569172856 0.6922683232211668 1.0 1.0 4 Q9Y6K9 1 +Abnormality of hair growth 0.4201595743459483 0.3955663936873209 0.6924249330314953 1.0 1.0 6 P04080,P78536 2 +Natal tooth 0.4041994454470897 0.3932483976213266 0.6941360269924073 1.0 1.0 8 O75844 1 +Cough 0.3572756056117728 0.3875881322407998 0.6983208528133682 1.0 1.0 25 P01889,P04062,P10644 3 +Prominent nasolabial fold 0.4172371572422625 0.386669112395441 0.6990011855853071 1.0 1.0 6 O14656,Q8NCH0 2 +Paraplegia paraparesis 0.3185241932410257 0.3863048038086927 0.6992709432000255 1.0 1.0 83 Q13510,P04062,Q9BZH6,P07942,Q8N0X7,Q9Y3Z3,O00400,O00754,O43678,Q92734,O95831,P11166 12 +Neoplasm of the endocrine system 0.3439197529412776 0.3841605181746014 0.7008594792071556 1.0 1.0 39 P42892,O00170,P10644 3 +Vascular neoplasm 0.348632887852643 0.3834903562857403 0.7013562193096092 1.0 1.0 35 P10619,Q7LGA3 2 +Suicidal ideation 0.5737716918841237 0.3815556641643897 0.702790975296752 1.0 1.0 3 Q14203 1 +Neoplasm of the stomach 0.359592287774865 0.3815185250088685 0.7028185278494434 1.0 1.0 21 Q15645,P60866,P43246,P42771,Q07812,P10644 6 +Relative macrocephaly 0.3502223338992017 0.3798470363609487 0.7040589645473658 1.0 1.0 32 Q7LGA3,O75844,Q15392 3 +Amelogenesis imperfecta 0.4666176673454613 0.3754421810993132 0.7073316393403661 1.0 1.0 4 Q9HC07,Q6P4Q7 2 +Limb joint contracture 0.3275188385188085 0.3748585580365211 0.7077656612731902 1.0 1.0 105 P42892,Q8IZA0,Q8TD16,Q7LGA3,Q9ULC3,Q14118,P63241,Q9Y619,Q9Y6K9,O00459,O75844,Q15392,P06753,Q99720 14 +Elevated hepatic transaminase 0.3257049773159434 0.3725886687446983 0.7094546075898709 1.0 1.0 103 P01889,Q13510,P28070,Q14739,Q15904,P10253,O43772,P38571 8 +Pulmonary artery stenosis 0.3614944267602492 0.3720646279785323 0.70984473155592 1.0 1.0 17 Q15056,P49459,P51798,Q04721 4 +Tall stature 0.3343259460533949 0.3715261939375773 0.7102456498798606 1.0 1.0 54 Q96PZ0,P04350,Q13423,Q7LGA3,P43034,O00170,O00754,P06753,P10644 9 +Self mutilation 0.3718418067482375 0.3687910101512272 0.7122835059609023 1.0 1.0 11 Q10713,Q9UBM7 2 +Axonal degeneration 0.4108598588227102 0.367587360374333 0.7131809409279981 1.0 1.0 6 Q92734,Q6UWE0,Q9UHD8,Q9Y5B0 4 +Esophageal carcinoma 0.5769459298871168 0.3675074537438997 0.7132405329634857 1.0 1.0 2 P42224 1 +Abnormal bronchus physiology 0.410800124452314 0.367410834782203 0.7133125909057092 1.0 1.0 6 Q9H0U9 1 +Bronchospasm 0.410800124452314 0.367410834782203 0.7133125909057092 1.0 1.0 6 Q9H0U9 1 +Disproportionate tall stature 0.348698319468944 0.3649195275229676 0.7151714771777167 1.0 1.0 28 O00754 1 +Somatic mutation 0.3376624084277404 0.3614441912522463 0.7177674177898021 1.0 1.0 41 P11717 1 +Decreased circulating progesterone 0.4080484298525709 0.3593243569412471 0.7193524551883801 1.0 1.0 6 Q13144,Q9NR50 2 +Abnormal circulating progesterone level 0.4080484298525709 0.3593243569412471 0.7193524551883801 1.0 1.0 6 Q13144,Q9NR50 2 +Abnormality of circulating enzyme level 0.3195706628371322 0.3591397220438059 0.719490567218017 1.0 1.0 97 Q14126,Q9H173,O43505,P13473,Q14118,Q15056,Q9HC07,P10253,O43772,Q92734,P49768,O95831 12 +Triangular mouth 0.3938091749004511 0.3587201943716303 0.7198044196055291 1.0 1.0 8 P11047,Q10713 2 +Underdeveloped supraorbital ridges 0.3607637096418122 0.358389478522745 0.7200518643746698 1.0 1.0 14 P98175,Q9ULC3,Q08J23 3 +Abnormality of lower limb epiphysis morphology 0.3596420909878536 0.3580884797002522 0.7202771000756356 1.0 1.0 16 Q9H173,Q7LGA3 2 +Redundant neck skin 0.4070403837675985 0.3563843310660794 0.7215527620868698 1.0 1.0 6 O96000 1 +Neoplasm of the oral cavity 0.3596695285092255 0.3536811929880035 0.7235778185829684 1.0 1.0 14 O43924 1 +Cutaneous syndactyly 0.375232859820801 0.3507077901447577 0.7258075806427915 1.0 1.0 10 Q9Y619,P27635,Q2M1P5 3 +Cerebellar vermis atrophy 0.3647932947819809 0.3503423786364495 0.7260817644919269 1.0 1.0 12 Q10713 1 +Paralysis 0.3317887444307928 0.3502170800778589 0.7261757894313932 1.0 1.0 54 P04062,P51798,Q96PY6,P10253,Q9NP58,P17900,Q14203,P11166 8 +Lipodystrophy 0.3415202817788851 0.3483300535021023 0.7275923259980437 1.0 1.0 37 Q14126,P04066,P28070,O75844,P49768 5 +Ectrodactyly 0.3545157147939484 0.3453285750665127 0.7298473666711698 1.0 1.0 18 Q99720 1 +Polydactyly 0.3307538583506804 0.3420654051842077 0.7323016714247927 1.0 1.0 55 O43924,Q9ULC3,Q14739,Q9UBM7,Q96PY6,Q10713,O00459 7 +Abnormal gastrointestinal motility 0.3464613237540402 0.3407682020253155 0.7332780903081566 1.0 1.0 27 P06280 1 +Male reproductive system neoplasm 0.3592440758524401 0.3387059877333272 0.734831229469652 1.0 1.0 13 Q13423 1 +Aplasia hypoplasia of the lungs 0.3401429934444323 0.3386825080527629 0.7348489192508751 1.0 1.0 37 Q15643,Q14739,Q9UBM7,Q96PY6,O75844 5 +Blue irides 0.3788648634014291 0.3363683875546489 0.7365930851325748 1.0 1.0 9 P10644 1 +Fair hair 0.4508692423933164 0.3362121648944282 0.736710880078947 1.0 1.0 4 Q05086,P10644 2 +Abnormal epiphyseal ossification 0.3539192485788611 0.3361755927198794 0.7367384571089037 1.0 1.0 17 Q14739,Q9UBM7 2 +Congestive heart failure 0.3278739727396579 0.3358300105165105 0.7369990580412344 1.0 1.0 64 P06280,Q15056,P10253,Q9Y6K9,P16278,P10644 6 +Variable expressivity 0.3113337361040078 0.3349225765322623 0.7376834910743377 1.0 1.0 85 P04350,Q70HW3,Q13510,P06753,Q8TD16,Q9BUF5,P43034,Q14118,Q9Y3Z3,Q13885,Q9H061,O15121,P17900,P07602,Q9NUM4,P11166 16 +Aplasia hypoplasia of the patella 0.4153425326650486 0.3338423570367131 0.7384985189559423 1.0 1.0 5 O75419,Q9Y619 2 +Arthrogryposis multiplex congenita 0.3303983769589915 0.3338218957809631 0.7385139598560113 1.0 1.0 43 P04062,P06753,O75844,Q15392,Q8TD16 5 +Infection related seizure 0.3475091826380531 0.3312897255742175 0.7404256513525118 1.0 1.0 25 P05067 1 +Thoracic aortic aneurysm 0.3407601098148292 0.3298295808179203 0.7415287347035804 1.0 1.0 35 P01889,Q7LGA3,Q06787,Q15056,O75844,P06753 6 +Pelvic kidney 0.3760061684011873 0.3267732482196059 0.743839394455418 1.0 1.0 9 Q15056 1 +Aplasia hypoplasia of metatarsal bones 0.3820728402103741 0.3213071894674182 0.747977608636551 1.0 1.0 8 Q9H173 1 +Absent septum pellucidum 0.3352335870691475 0.3211853008541065 0.7480699707340102 1.0 1.0 39 Q9BZH6,O43505,Q14118,Q15392,Q9Y6N7,O60524,Q08J23,Q13409 8 +Neoplasm of the pituitary gland 0.3514357866481661 0.3208320951906058 0.748337635641775 1.0 1.0 16 O75874,O00170,P10644 3 +Abnormality of alkaline phosphatase level 0.3462332927008934 0.3187606175073922 0.7499080442433952 1.0 1.0 24 P51798,Q96JJ3,Q14739,P38571,Q9H9E3 5 +Abnormal blood phosphate concentration 0.3659587443431422 0.3180150350992609 0.750473532139486 1.0 1.0 10 P10644 1 +Chylothorax 0.4429372928900194 0.3175252999836167 0.7508450453276521 1.0 1.0 4 Q02750 1 +Generalized tonic seizure 0.3473868858433535 0.3173149766121497 0.751004614431932 1.0 1.0 21 Q14746,Q01105,P43034,P67870 4 +Short foot 0.340905410817266 0.3164144767113663 0.7516879301767863 1.0 1.0 29 Q15643,Q8N0X7,Q06787,P49459,Q9NX62 5 +Complete atrioventricular canal defect 0.4405469678953517 0.3120393518272986 0.7550106169212729 1.0 1.0 4 O75419,Q9UHX1,P17612 3 +Renal duplication 0.3711351089923656 0.3106770358279861 0.7560461566907213 1.0 1.0 9 Q15056 1 +Abnormal urine protein level 0.3266358907977877 0.3102366139133338 0.7563810292650746 1.0 1.0 58 Q14108,P04062,P06280,Q15056,P11047 5 +Aplasia hypoplasia affecting the eye 0.3164636883661982 0.3081381907486685 0.7579771820833676 1.0 1.0 99 O15347,O75312,O43924,Q9BZH6,Q9BXW9,Q7LGA3,Q9P273,O43505,Q9UBM7,Q14118,P11047,Q15056,P07437,Q9Y6K9,Q9NP58,Q9Y6N7,P11166 17 +Abnormal clavicle morphology 0.3448036933774394 0.3072476880956703 0.7586548499033867 1.0 1.0 23 Q15643,Q14739,Q96PY6,Q9Y619,O75844 5 +Abnormality of skin pigmentation 0.3428593023833187 0.30553035392771 0.7599622553602856 1.0 1.0 134 Q9BXW9,Q13423,Q7LGA3,O00170,Q9Y6K9,P07602,Q8IZA0,P51798,Q14739,P49459,P53634,Q8ND04,P10644,O75312,P04062,P07437,Q9NP58,O75844,Q08J23 19 +Motor seizure 0.324913912610764 0.3044848553039235 0.7607585290747725 1.0 1.0 110 Q13510,P04062,O75503,Q8NB90,P07686,P16278,P07602 7 +Acral ulceration 0.5384843982169406 0.303980688134479 0.761142604036563 1.0 1.0 3 Q12756,Q9H4A3 2 +Autoamputation of digits 0.5384843982169406 0.303980688134479 0.761142604036563 1.0 1.0 3 Q12756,Q9H4A3 2 +Pancreatic cysts 0.3872694824509203 0.3012546219699702 0.7632203408858376 1.0 1.0 6 Q14697,Q96J42,Q9NQH7,O15078,Q9Y5S9 5 +Cystic liver disease 0.3872694824509169 0.3012546219699613 0.7632203408858445 1.0 1.0 6 Q14697,Q96J42,P14314,O15078,Q9UGP8 5 +Abnormal circulating creatinine concentration 0.3872694824509153 0.3012546219699569 0.7632203408858478 1.0 1.0 6 Q16658,Q14697,Q10471,P00492,O95163 5 +Abnormality of the pulmonary vasculature 0.3241471908230782 0.3005229393250139 0.763778301553993 1.0 1.0 44 Q96PZ0,P51798,Q7LGA3,O75718,Q15056,P49459,Q04721,Q15392,Q8ND04 9 +Wide cranial sutures 0.3816809058148294 0.2993641659502991 0.7646622005675783 1.0 1.0 7 O75718,O75844 2 +Patent ductus arteriosus 0.3063318539893678 0.2978628650517594 0.7658078315298029 1.0 1.0 88 P42892,Q15643,Q9BXW9,Q9ULC3,Q9UBM7,Q15056,P49459,O75844,Q15392,Q96PU5 10 +Fused cervical vertebrae 0.3811365664980676 0.2978342316234026 0.7658296864620324 1.0 1.0 7 Q9Y2W2,Q9UHB7,Q9NVI1,Q9Y5S9,Q9UHX1,P21333 6 +Abnormal cellular phenotype 0.3801394970656814 0.297011901549755 0.7664574228069057 1.0 1.0 197 O14773,Q9BXW9,O96000,P15586,O75503,Q9Y6K9,P02786,P07602,Q4J6C6,Q14108,P78536,Q14739,O43772,O00754,Q13510,P28070,Q15126,Q15904,P11166,P04062,O43678,O75844,P13051 23 +Conical tooth 0.3597782576059186 0.296901486946852 0.766541720913593 1.0 1.0 10 Q9Y6K9,Q12959,Q96PY6 3 +Kyphoscoliosis 0.3249756413994302 0.2949531352478644 0.7680296804590712 1.0 1.0 57 O15347,O94992,P04350,Q8N0X7,Q9ULC3,Q9HC07,Q5KU26,Q9Y6K9,Q04721,O75844,P06753 11 +Severe muscular hypotonia 0.3366805050381611 0.2945925939776372 0.768305120385588 1.0 1.0 33 O43505,P67870,P06753,Q01105,O95831 5 +Abnormality of the distal phalanx of the thumb 0.4326778134486715 0.2944644308374709 0.76840303923901 1.0 1.0 4 Q2M1P5 1 +Simplified gyral pattern 0.3372422545310749 0.2939887380753081 0.7687665090292213 1.0 1.0 29 O94992,Q5KU26,P35606,Q86XL3,Q13409 5 +Symphalangism of middle phalanx of finger 0.5442661913250261 0.2937599608098957 0.7689413324549739 1.0 1.0 2 Q15233 1 +Abnormality of the septum pellucidum 0.3242891940589768 0.2928582576555121 0.7696304961790053 1.0 1.0 48 Q9BZH6,O43505,P43034,Q14118,Q15392,Q9Y6N7,O60524,Q8ND04,Q08J23,Q13409 10 +Speech articulation difficulties 0.3987511150758337 0.292383939633199 0.7699930863224556 1.0 1.0 5 Q8N3U4,P42858,Q12959,P08754 4 +Heterophoria 0.531946508172364 0.2909943952386282 0.7710556060707483 1.0 1.0 3 Q9ULH0,Q9UHB7 2 +Abnormal platelet morphology 0.3828078524687606 0.2895105799327617 0.7721906847734397 1.0 1.0 6 O00203,Q86YV9,O75845,P12814,P27797 5 +Aphasia 0.3279937138989885 0.2895057230475014 0.7721944009617752 1.0 1.0 41 P05067,Q9NUM4 2 +Hyperhomocystinemia 0.5418894830659621 0.288899477056117 0.7726583039213304 1.0 1.0 2 Q99707 1 +High pitched voice 0.3492613642038349 0.2861357824831659 0.7747741262814385 1.0 1.0 11 O75844 1 +Nocturnal hypoventilation 0.5395127748069042 0.2841087783095491 0.7763270199278733 1.0 1.0 2 Q9Y281 1 +Large intestinal polyposis 0.3626079190235139 0.283298059490479 0.7769483646849795 1.0 1.0 9 P04637,P20585,Q15437,Q07864,P42771,O96017,P28340,Q9UPY3 8 +Colorectal polyposis 0.3626079190235139 0.283298059490479 0.7769483646849795 1.0 1.0 9 P04637,P20585,Q15437,Q07864,P42771,O96017,P28340,Q9UPY3 8 +Receptive language delay 0.3428197827616507 0.282830574411844 0.7773067158330038 1.0 1.0 16 Q8NB90 1 +Self injurious behavior 0.322640949172875 0.2797487706985155 0.7796702579474744 1.0 1.0 48 P19022,Q9UBM7,P67870,Q8NB90,P49459,Q10713,Q8ND04,Q01105 8 +Prominent nasal bridge 0.3227412146726655 0.278931194181246 0.7802976287179177 1.0 1.0 49 O43924,P42892,Q10713 3 +Patellar aplasia 0.4250732204221527 0.2782000026533126 0.780858832823569 1.0 1.0 4 O75419,Q9Y619 2 +Secondary microcephaly 0.3120038356919677 0.2781964069319805 0.7808615928938583 1.0 1.0 79 O94992,Q14746,P43034,Q9NR50,Q9HC07,Q5KU26,P50897,Q15043,P11166 9 +Abnormal serum interleukin level 0.5243348270573717 0.2764425113922429 0.7822082089554183 1.0 1.0 3 Q15833 1 +Abnormal labia minora morphology 0.372810731602756 0.274937367903703 0.7833643575726463 1.0 1.0 7 Q9H2M9,Q9Y619 2 +Vertebral wedging 0.533868092691634 0.2730117718116034 0.7848441666091035 1.0 1.0 2 Q96AY3 1 +Fatigable weakness of bulbar muscles 0.3405237923046326 0.2729102925619027 0.7849221744328068 1.0 1.0 16 Q9UQN3,Q96PY6,Q99700,P06753,Q14203 5 +Thick cerebral cortex 0.4221380477475918 0.2721145770901423 0.7855339214238912 1.0 1.0 4 P43034 1 +Aplasia hypoplasia of the earlobes 0.3756271817337179 0.2711756482466736 0.786255941378879 1.0 1.0 6 P10586 1 +Abnormal oral physiology 0.3220175982051431 0.2709779757578477 0.7864079715341592 1.0 1.0 58 P01889,P15586,Q8N0X7,Q14739,Q96PY6,P11047,P06753,Q14203,P10644 9 +Abnormal left ventricular outflow tract morphology 0.4212247324613417 0.2702430532090236 0.7869732727526386 1.0 1.0 4 O43684,Q15645,Q06124 3 +Subvalvular aortic stenosis 0.4212247324613417 0.2702430532090236 0.7869732727526386 1.0 1.0 4 O43684,Q15645,Q06124 3 +Psychomotor retardation 0.3267794589641097 0.2701004633556206 0.7870829656488056 1.0 1.0 40 P04062,P07942,Q9H173,P11047,O00400,P16278 6 +Tapered finger 0.3288562253611203 0.2675817018201922 0.789021317333396 1.0 1.0 38 P42892 1 +Decreased testicular size 0.3364786115134639 0.2655417225147606 0.7905921731492618 1.0 1.0 24 O75312,Q9UJA3,Q9BZH6,O43505,Q06787,P27635 6 +Abnormality of salivation 0.3198841597787186 0.2647049063618711 0.7912367975550587 1.0 1.0 45 P01889,P15586,Q8N0X7,Q14739,Q96PY6 5 +Ovotestis 0.5294117647058945 0.2645314445757356 0.7913704382181304 1.0 1.0 2 P53701 1 +Aggressive behavior 0.3103418019675059 0.2616631827426534 0.7935811276860218 1.0 1.0 79 P54802,O75503,Q9UBM7,P49459,Q10713,Q9NUM4 6 +Open mouth 0.3311420970512503 0.2590069572623077 0.7956298725039321 1.0 1.0 33 Q96PZ0,P04350,P04062,P62266,P67870,Q86XL3,Q10713,P10644 8 +Hypocalcemia 0.3368956517177572 0.2574202149470354 0.796854399296457 1.0 1.0 16 P10644,Q4J6C6 2 +Decreased methylcobalamin 0.5249554367201508 0.2562995340994442 0.7977195569771482 1.0 1.0 2 Q99707 1 +Angiofibromas 0.4136406328607728 0.2551091200102853 0.7986388204168762 1.0 1.0 4 P43246,P52701 2 +Adenoma sebaceum 0.4136406328607728 0.2551091200102853 0.7986388204168762 1.0 1.0 4 P43246,P52701 2 +Abnormal pulmonary valve morphology 0.3359352116954613 0.2539259978721563 0.7995527295062772 1.0 1.0 15 P51798,P10644 2 +Peripheral pulmonary artery stenosis 0.3396573484488652 0.2533576766475417 0.7999918300163142 1.0 1.0 11 Q15056,P49459 2 +Emotional lability 0.3196180332513501 0.2532967063476882 0.8000389410941788 1.0 1.0 60 Q8N0X7,P02792,Q9NR50,Q96PY6,O00170,O43678,P07602,P10644 8 +Abnormal atrioventricular valve morphology 0.3297678933485209 0.2528700425602745 0.8003686398455874 1.0 1.0 34 Q15056,P06753,P04062,O75844 4 +Hypoplastic heart 0.4111177170035553 0.2502368118060695 0.8024042189066487 1.0 1.0 4 P24468,Q12768,O60826 3 +Pyoderma gangrenosum 0.5193107546048847 0.2462298965616261 0.8055042737418088 1.0 1.0 2 O75083 1 +Low set posteriorly rotated ears 0.3096216291613854 0.2460565502292066 0.8056384570608801 1.0 1.0 78 Q9H2M9,O43924,Q8NCH0,P04062,Q96J42,Q02750,Q9UBM7,P07437,Q15056,Q2M1P5,P37268,Q10713,Q15392,P98175,Q96J02,Q08J23,Q4J6C6 17 +Narrow foot 0.5187165775401184 0.2451931949700699 0.8063068452268405 1.0 1.0 2 O60828 1 +Muscle fiber atrophy 0.3331236764445685 0.2448180705766729 0.8065973013275309 1.0 1.0 22 P11047,Q99720 2 +Agenesis of maxillary incisor 0.5178253119429717 0.2436464511392721 0.8075046493649529 1.0 1.0 2 P41227 1 +Aplasia hypoplasia involving bones of the lower limbs 0.3027762392205914 0.2417957139765247 0.8089384601396037 1.0 1.0 90 Q15643,Q13510,Q9H173,Q7LGA3,Q9ULC3,Q8N0X7,Q9UBM7,Q96PY6,Q06787,Q9Y619,P49459,Q08J23,O95831,P10644,Q9NX62 15 +Recurrent urinary tract infections 0.3278733579672758 0.2406615479555481 0.809817443394411 1.0 1.0 34 Q15056,Q13423,O00754,O94898 4 +Increased blood urea nitrogen 0.5154486036839101 0.2395705392402604 0.810663206004562 1.0 1.0 2 O95163 1 +Aplasia hypoplasia of the radius 0.3322650675345217 0.2385311238514047 0.8114691785368375 1.0 1.0 17 Q15643,P10644,Q9UBM7 3 +Bilateral microphthalmos 0.3743158569101587 0.2379683506928905 0.8119056416202393 1.0 1.0 5 P18074 1 +Recurrent mycobacterial infections 0.5142602495543751 0.2375591613675772 0.8122230282826908 1.0 1.0 2 P42224 1 +Cupped ribs 0.3577092372900916 0.2359145892683802 0.8134989471448126 1.0 1.0 7 Q5F1R6,O95831 2 +Abnormal thrombosis 0.3292390239051586 0.2299691324942203 0.8181157556178342 1.0 1.0 25 P01889,P10644,P38571 3 +Rotary nystagmus 0.3998216409036818 0.2294242905543144 0.8185391584636736 1.0 1.0 4 Q5T8D3,Q14738,Q9Y4R8 3 +Lower limb metaphyseal irregularity 0.3995243757431496 0.2288988421213822 0.8189475405330178 1.0 1.0 4 P61011,Q5F1R6,Q9Y3A5 3 +Increased circulating igg level 0.4965824665676095 0.2286565918350208 0.8191358356411118 1.0 1.0 3 O95394,P29144 2 +Recurrent herpes 0.3989298454221044 0.2278513798127863 0.8197617817661285 1.0 1.0 4 P54132,P42224,P29144 3 +Abnormal thyroid hormone level 0.5062388591800486 0.2244451639298781 0.8224109312303081 1.0 1.0 2 O14654 1 +Neoplasm of the rectum 0.3270721526535394 0.222077532665418 0.8242535275115546 1.0 1.0 14 Q16658,P04637,P21912,P20585,P60866,Q15437,Q07864,P43246,P42771,P52701,O96017,P28340,Q9UPY3 13 +Slender build 0.3264405491102705 0.219711538925316 0.8260958174826094 1.0 1.0 14 P06753,P10644 2 +Conjugated hyperbilirubinemia 0.3642001329466171 0.2178715389642822 0.8275292030772274 1.0 1.0 5 P11166 1 +Abnormality of the calcaneus 0.3501334692049461 0.2176102127550928 0.827732826550813 1.0 1.0 7 Q14739 1 +Eeg with multifocal slow activity 0.340279845192017 0.2168052874411122 0.8283600911837763 1.0 1.0 9 Q96F07,O95319,P61981,Q00610,Q08209,Q9GZZ9,Q05639,P49588 8 +Bladder neoplasm 0.3452380952380973 0.2163104790719049 0.8287457413039259 1.0 1.0 8 P04637,P63167,O14965,P06400,Q07812,O96017,O60566 7 +Leiomyosarcoma 0.3452380952380973 0.2163104790719049 0.8287457413039259 1.0 1.0 8 P04637,P63167,O14965,Q07812,O96017,O60566,P07954 7 +Hereditary nonpolyposis colorectal carcinoma 0.3452380952380971 0.2163104790719041 0.8287457413039265 1.0 1.0 8 P04637,P63167,P52701,O14965,Q07812,O96017,O60566 7 +Spastic paraparetic gait 0.3620143695524435 0.2137204994892181 0.8307650243949989 1.0 1.0 5 Q15043 1 +Sarcoma 0.3146254145218925 0.2108710810634188 0.8329878706806872 1.0 1.0 60 P08708,P42771,Q07954,P42766,P60866,O75874,Q07812,Q01844,P62273,Q15645,Q02750,Q96JJ3,P06400,P46777,Q15392,P10644,P62913,P43246,P46783 19 +Antiphospholipid antibody positivity 0.4964349376114159 0.2095067975118531 0.8340526294846136 1.0 1.0 2 P42224 1 +Lower limb asymmetry 0.3485801440545036 0.2087025808571856 0.8346804252755522 1.0 1.0 6 P28482,P07437 2 +Lower limb amyotrophy 0.3247765591693272 0.20775145224696 0.8354230409554004 1.0 1.0 18 Q8TD16,P06753,O00400,Q92734 4 +Generalized joint laxity 0.3253055332352143 0.2075731921586114 0.8355622379949925 1.0 1.0 12 Q9UHX1,Q9BZH6,Q9BUK6,Q8NCH0 4 +Sleep disturbance 0.3483258398251964 0.2063628641144073 0.8365074766299283 1.0 1.0 156 P15586,Q7LGA3,O75503,Q9UBM7,P67870,O00170,P50897,P54802,Q9H0U9,P06753,Q8N0X7,P02792,Q06787,P11047,O95831,P11166,P04062,Q15056,Q14203,Q01105,Q08J23 21 +Functional abnormality of the gastrointestinal tract 0.404638146383782 0.2063582647754536 0.8365110690600712 1.0 1.0 288 P42892,P15586,P61916,Q9UBM7,P06280,P67870,P05067,P07602,Q14108,Q8IZA0,P78536,P08183,O75874,Q14739,Q9H0U9,O00754,P49768,P06753,Q6YHK3,Q13510,O15118,Q8N0X7,P02792,P63241,P11047,Q06787,Q96PU5,Q99720,P29372,P01889,P04062,P62913,Q96PY6,Q15056,Q9Y619,Q92734,Q01105 37 +Abnormality of female external genitalia 0.3213399539000055 0.2053720735640059 0.8372814373020221 1.0 1.0 36 Q9Y619,P10644,Q9UBM7,Q15392 4 +Aplasia hypoplasia of the palmar creases 0.4805349182763762 0.2048394929443349 0.837697530275588 1.0 1.0 3 Q99567,Q8NCH0 2 +Abnormality of circulating glucocorticoid level 0.323626195563919 0.2043590299389885 0.8380729439098182 1.0 1.0 13 Q13423 1 +Abnormality of corneal size 0.3120167030108655 0.2042656297552359 0.8381459271768075 1.0 1.0 45 O15347,Q9H2M9,Q96J42,Q9P273,Q9ULC3,O43505,Q14118,P07437,Q15056,Q8NCH0 10 +Aplasia hypoplasia of the sternum 0.3845155331362654 0.2038598728977637 0.8384630033200464 1.0 1.0 4 Q9Y619 1 +Horizontal eyebrow 0.3441028618549928 0.2036673882517067 0.8386134284112041 1.0 1.0 7 P78536 1 +Primary microcephaly 0.3219217248523249 0.203010101818533 0.8391271365096615 1.0 1.0 14 Q8NB90 1 +Limitation of knee mobility 0.3837693222354277 0.2026913175105929 0.8393763099400309 1.0 1.0 4 Q14315,O14656,P55072 3 +Potter facies 0.491087344028534 0.2018595236357326 0.8400265460937928 1.0 1.0 2 P22314 1 +Abnormal blood chloride concentration 0.4781575037147118 0.201548272125595 0.8402698880574397 1.0 1.0 3 Q9H4A3,Q9UNF1 2 +Vaginal neoplasm 0.382877526753858 0.2013042525537128 0.8404606775734755 1.0 1.0 4 O43684,O60566,Q15645 3 +Lung adenocarcinoma 0.3825802615933378 0.2008441891983654 0.8408204088960967 1.0 1.0 4 Q14790,Q92560,P30154 3 +Central primitive neuroectodermal tumor 0.382580261593328 0.2008441891983501 0.8408204088961087 1.0 1.0 4 O96017,P42771,Q9UPY3 3 +Abnormal ovarian physiology 0.3208586009258214 0.1991019500804111 0.8421829958256022 1.0 1.0 28 Q9UJA3,Q9BZH6,Q06787,Q9NR50,O00170,O75844 6 +Abnormal c reactive protein level 0.4757800891530477 0.198317915824937 0.8427963352645118 1.0 1.0 3 P14174,P22314 2 +Aplasia hypoplasia of the abdominal wall musculature 0.3807966706301915 0.1981078571865629 0.8429606775227216 1.0 1.0 4 P22681,Q6NUK1,Q06124 3 +Abnormal astrocyte morphology 0.3218531364844491 0.1975217401395055 0.8434192703798669 1.0 1.0 19 O95831,O75874,Q9NUM4 3 +Erythrocyte inclusion bodies 0.380202140309147 0.1972049023596613 0.8436671944202414 1.0 1.0 4 Q9Y606,P11413,P08865 3 +Pulmonary artery atresia 0.4734026745913835 0.1951482506526646 0.8452768900781749 1.0 1.0 3 Q96HP0,Q8WYQ5 2 +Nail dysplasia 0.3209192487956622 0.1948323705185157 0.8455241798593391 1.0 1.0 33 P42892 1 +Adrenal insufficiency 0.3200212392443219 0.1943385888839066 0.8459107720116741 1.0 1.0 28 Q13423,P38571 2 +Branchial fistula 0.3411526568289577 0.1934461383677861 0.8466095845767803 1.0 1.0 6 P28482,P11274,O15160 3 +Thenar muscle atrophy 0.4716196136701353 0.1928107142670704 0.8471072121676313 1.0 1.0 3 P41250,O60568 2 +Dilated cardiomyopathy 0.3145329612040836 0.1920657620386904 0.8476906935128241 1.0 1.0 41 P13473,P16278 2 +Craniosynostosis 0.3177371576871188 0.1915607607453328 0.8480862815912515 1.0 1.0 38 P51798,Q9ULC3,Q9Y619,O00754,Q9NX62 5 +Cystic renal dysplasia 0.4827688651218201 0.1906574814502059 0.8487939524303372 1.0 1.0 2 Q8TD19 1 +Elevated circulating long chain fatty acid concentration 0.4827688651218158 0.1906574814502005 0.8487939524303414 1.0 1.0 2 P40855 1 +Renal insufficiency 0.302272289482625 0.1903302508744685 0.8490503501249216 1.0 1.0 80 Q14108,P01889,Q9BXW9,O94898,P06280,P11047,Q15056,Q10713 8 +Abnormal sternal ossification 0.3744986669467168 0.1887747411995018 0.8502693694857992 1.0 1.0 4 Q9Y619 1 +Pediatric onset 0.3908463640810765 0.1883492974088449 0.8506028430718402 1.0 1.0 245 O14773,O00584,P06280,O00400,P07602,P06865,P22466,P54802,Q9H173,Q14574,P49459,P16278,Q02487,Q13510,O15118,Q15904,Q10713,P07686,P38571,O95831,P11166 21 +Arterial rupture 0.4803921568627551 0.1876102611103243 0.8511821818785743 1.0 1.0 2 Q02809 1 +Aplasia hypoplasia of the clavicles 0.3185955915731397 0.1872299769112363 0.8514803222308922 1.0 1.0 13 Q15643,O75844 2 +Atonic seizure 0.3213515158810871 0.1864398451443538 0.8520998482530819 1.0 1.0 24 Q01105,Q13510,P67870,P11166 4 +Tetraparesis 0.3160295493351934 0.1863916097915759 0.8521376715581133 1.0 1.0 39 P07602 1 +Hyperchloremic acidosis 0.4780154486036979 0.1846304747854329 0.8535188814388146 1.0 1.0 2 Q9H4A3 1 +Pseudohypoaldosteronism 0.4780154486036979 0.1846304747854329 0.8535188814388146 1.0 1.0 2 Q9H4A3 1 +Abnormality of the adrenal glands 0.3114124008776252 0.1838377363308542 0.8541407513151285 1.0 1.0 60 Q9BZH6,Q13423,O00170,P38571,Q9Y6N7,O75844,P10644 7 +Abnormality of upper limb epiphysis morphology 0.3190754830785287 0.1832575560989128 0.8545959356937385 1.0 1.0 18 Q15643,Q9ULC3,P10644 3 +Eversion of lateral third of lower eyelids 0.4762329174094022 0.1824396258429783 0.8552377306616612 1.0 1.0 2 P61978 1 +Abnormal dlco 0.4756387403446369 0.1817176840790624 0.8558042871467011 1.0 1.0 2 O95453 1 +Chronic axonal neuropathy 0.4606818720351903 0.1792104923762667 0.8577724253740973 1.0 1.0 3 P04792 1 +Pancreatic adenocarcinoma 0.3296872366987962 0.1782921488658085 0.8584935443299957 1.0 1.0 8 P60866,P43246,P42771,P52701 4 +Lipid accumulation in hepatocytes 0.3071075187019407 0.1773846759730662 0.8592062432499641 1.0 1.0 71 P01130,Q15904,O43772 3 +Abnormal nephron morphology 0.310342418372759 0.1760547341530569 0.860250942291914 1.0 1.0 61 Q14108,P01889,P06280,P11047,Q15056 5 +Milia 0.3647443519619429 0.1753253960129727 0.8608239576915746 1.0 1.0 4 P50336,Q9H4L7,P23229 3 +Urethral stricture 0.3647443519619394 0.1753253960129683 0.8608239576915782 1.0 1.0 4 O75419,P23229,P09884 3 +Menorrhagia 0.4573551263001503 0.1753233625012945 0.8608255554529636 1.0 1.0 3 P35579,P49257 2 +Juvenile myelomonocytic leukemia 0.4568641491537673 0.1747594275637233 0.8612686697641039 1.0 1.0 3 Q02750 1 +Myeloid leukemia 0.4568641491537673 0.1747594275637233 0.8612686697641039 1.0 1.0 3 Q02750 1 +Abnormality of the hallux 0.3101068020016631 0.173276408772239 0.8624341662622652 1.0 1.0 53 Q96PZ0,P04792,P04062,Q7LGA3,Q9ULC3,Q96PY6,Q2M1P5,Q15056,P49459,P10644 10 +Abnormal myocardium morphology 0.356755881546835 0.1731388368899228 0.8625422984854749 1.0 1.0 175 Q14108,P01889,Q14126,Q02487,P04062,P15586,P54802,Q13423,P13473,P06280,P10253,O43772,P16278 13 +Retinal coloboma 0.3177816169917536 0.1696990694290278 0.8652468059452665 1.0 1.0 10 Q9H2M9,Q10713 2 +Multiple joint contractures 0.3153214940354983 0.1686672181330029 0.8660584054346894 1.0 1.0 19 O75844,Q15043 2 +Osteomalacia 0.3587990487514747 0.1677205714828108 0.8668031117373585 1.0 1.0 4 P53680,Q9Y617,Q01968 3 +Failure to thrive in infancy 0.3162936362134445 0.1668929134720379 0.867454309178461 1.0 1.0 31 Q15056,P42892 2 +Temporal optic disc pallor 0.4625668449198008 0.1668729218414773 0.8674700396140334 1.0 1.0 2 O00429 1 +Morning glory anomaly 0.4625668449198008 0.1668729218414773 0.8674700396140334 1.0 1.0 2 O00429 1 +Abnormality of globe size 0.3082114238075448 0.1655499702565389 0.8685111218083605 1.0 1.0 65 O15347,O43924,Q96J42,Q9BXW9,Q9P273,O43505,Q14118,Q2M1P5,P07437,Q9Y6K9,O00459,Q9NP58,P11166 13 +Abnormal esophagus physiology 0.3842489579444217 0.1650096200810078 0.8689364101257482 1.0 1.0 233 P15586,P61916,Q9UBM7,P06280,P67870,P05067,P07602,Q14108,Q8IZA0,O75874,Q14739,Q9H0U9,P49768,P06753,Q13510,O15118,Q8N0X7,P02792,P63241,P11047,Q06787,Q96PU5,Q99720,P01889,P04062,Q96PY6,Q15056,Q92734,Q01105 29 +Abnormality of the posterior pituitary 0.3103670506134101 0.1634728851447302 0.870146120476627 1.0 1.0 11 Q9Y6N7 1 +Albinism 0.4454680534918294 0.1623650064054672 0.8710184259938596 1.0 1.0 3 Q86YV9,O00203 2 +Abnormality of the nasal tip 0.3042419249440571 0.1614004970651454 0.8717779752044654 1.0 1.0 101 P42892,O43924,P10586,Q7LGA3,O75844,P16278,Q8ND04,O95831 8 +Yellow white lesions of the retina 0.4569221628045284 0.161062463523275 0.8720442039738547 1.0 1.0 2 P06400 1 +Overhanging nasal tip 0.440416047548293 0.1572897356557042 0.8750165093305386 1.0 1.0 3 P17612,Q9H9E3 2 +Chronic constipation 0.3136400555216305 0.1554535566113749 0.876463765215961 1.0 1.0 29 P49459,P78318,Q7LGA3,P04062 4 +Poor eye contact 0.307695493296163 0.1528842836219262 0.8784895300524576 1.0 1.0 42 O94992,Q5KU26,Q8NB90,O96000 4 +Viral encephalitis 0.4483065953654332 0.1528653931606582 0.8785044273584255 1.0 1.0 2 P42224 1 +Skin appendage neoplasm 0.3459362210949915 0.1527701458029881 0.8785795415330486 1.0 1.0 4 P43246,Q15437 2 +Csf pleocytosis 0.3454341830875955 0.1522275329790511 0.879007478846753 1.0 1.0 4 Q9Y3Z3 1 +Abnormal number of incisors 0.3178708826607151 0.1521116470991491 0.8790988780505891 1.0 1.0 8 Q96PY6 1 +Prolonged bleeding following procedure 0.4471182412358934 0.1517969051160143 0.8793471232076273 1.0 1.0 2 P49257 1 +Lissencephaly 0.3075666372865659 0.1513839641000607 0.8796728384710837 1.0 1.0 55 Q9H2M9,P07942,O43505,P43034,Q14118,Q96PY6,P35606,Q86XL3,O00459,Q9H9C1,Q15392 11 +Laryngeal cleft 0.4465240641711366 0.1512682117111555 0.8797641440768942 1.0 1.0 2 Q69YQ0 1 +Abnormality of the fetal cardiovascular system 0.3421521997621832 0.1487545868310862 0.8817472862971525 1.0 1.0 4 P26196,Q12768,O60826 3 +Atypical absence seizure 0.3406648590394024 0.1472228532365079 0.8829561228656599 1.0 1.0 4 P43034 1 +Abnormal patella morphology 0.3120957498148695 0.1454830447964993 0.8843295016180956 1.0 1.0 27 Q9ULC3,Q15056,Q9Y619,Q96PU5,Q9NX62 5 +Chronic leukemia 0.3388943495560852 0.1454334750011351 0.8843686363860694 1.0 1.0 4 Q9Y3Z3 1 +Scrotal hypoplasia 0.3108962091655313 0.1447527838408155 0.8849060625142218 1.0 1.0 20 Q9H2M9,Q8IWS0,Q9H0U9,Q9UBM7,P07437,P48444,O15160,P18074,Q8IY17 9 +Increased nuchal translucency 0.308414403005992 0.1446386095904082 0.88499621170906 1.0 1.0 16 Q9UBM7 1 +Autosomal dominant germline de novo mutation 0.4243684992570596 0.142812532080428 0.886438239369483 1.0 1.0 3 P28482,Q9HCK8 2 +Abnormal large intestine morphology 0.3014976777172717 0.1412180516205782 0.8876976858517733 1.0 1.0 74 P08708,P42771,P08183,P42766,P60866,Q07812,O15160,O15143,P62273,Q15645,Q2M1P5,P46777,P10644,Q15833,P01889,P62913,Q15056,P43246,P46783,O75844,Q08J23 21 +Gaze evoked nystagmus 0.3056568873445662 0.1388458047034262 0.8895719975904788 1.0 1.0 10 Q9UNE7,Q10713,Q99700 3 +Transient neutropenia 0.3128819049277064 0.1384644024774904 0.8898734012873881 1.0 1.0 5 Q7Z2Z2,Q5F1R6 2 +Hypoamylasemia 0.3128819049277064 0.1384644024774904 0.8898734012873881 1.0 1.0 5 Q7Z2Z2,Q5F1R6 2 +Abnormal cranial nerve physiology 0.2998982843245758 0.1380496437918237 0.8902011830433922 1.0 1.0 76 P01889,Q13510,P51798,Q9BXW9,O75874,P11047,O00170,Q92734,P07602,Q15043 10 +Abnormality of adrenal physiology 0.3111973553766134 0.137869398217513 0.8903436360908816 1.0 1.0 35 Q13423,O00170,P38571 3 +Recurrent bronchopulmonary infections 0.3098424026167203 0.134922381830578 0.8926732432149878 1.0 1.0 5 P26639,Q9Y2Q5,P18074,Q96AX1 4 +Panhypogammaglobulinemia 0.3098424026167201 0.1349223818305775 0.8926732432149882 1.0 1.0 5 Q15477,Q6PGP7,P18074,P26639 4 +Malrotation of small bowel 0.3263697626587731 0.1338058449650526 0.8935561051491543 1.0 1.0 4 Q8NCH0 1 +Gastritis 0.3062741599762179 0.1309225375109568 0.8958365857811248 1.0 1.0 5 P49327,Q6PGP7,Q15477,P50851 4 +Abnormal glial cell morphology 0.304601494967303 0.1292074179051221 0.8971935267746094 1.0 1.0 62 P04062,O75874,Q9NR50,Q10713,Q9NUM4,O00754,Q92734,O95831 8 +Aplasia hypoplasia involving forearm bones 0.3056657487605783 0.1277589908786097 0.8983397045725205 1.0 1.0 19 Q15643,P10644,Q9UBM7 3 +Narrow mouth 0.3028204344576485 0.1271991738211503 0.8987827592657944 1.0 1.0 68 Q96PZ0,P04062,P55201,Q7LGA3,P43034,P27635,P07437,Q9Y619,O00459,Q04721,O75844,Q15392,Q9NX62 13 +Hypotelorism 0.3094385078390535 0.1258187971222651 0.8998753620657787 1.0 1.0 34 Q9H2M9,Q9BXW9,Q8TD30,Q15904,O43776,P57081,P48444,P18074,Q08J23,Q9BUK6 10 +Hypopigmented macule 0.3006244424620962 0.1249336604609797 0.9005760699368508 1.0 1.0 5 Q9NP58,Q15233,Q15149,Q9H488 4 +Neoplasm of the tracheobronchial system 0.3988112927191699 0.1245650989934575 0.9008678601045867 1.0 1.0 3 P30154,Q9UPY3 2 +Broad chin 0.4084967320261525 0.1245418992372295 0.900886227803562 1.0 1.0 2 P55011 1 +Abnormality of the sense of smell 0.3087373177584966 0.1242186779680561 0.9011421338951742 1.0 1.0 24 P04062,Q15043 2 +Impaired vibratory sensation 0.3090907949691501 0.1239567432110233 0.9013495247537182 1.0 1.0 32 O00400,Q8N0X7,O14773,Q06787 4 +Hemivertebrae 0.2974103800224164 0.1208396860316328 0.9038180155052054 1.0 1.0 13 Q9Y6K9,P63241 2 +Heat intolerance 0.3008033323415731 0.1205795761186385 0.9040240466861268 1.0 1.0 7 Q02750,P00338,P61978,Q05086,P36507,Q9H488 6 +Aplasia of the semicircular canal 0.3998811645870533 0.1202258137158041 0.9043042696951902 1.0 1.0 2 Q06124 1 +Morphological abnormality of the vestibule of the inner ear 0.3998811645870533 0.1202258137158041 0.9043042696951902 1.0 1.0 2 Q06124 1 +Alveolar cell carcinoma 0.3986928104575264 0.1196745146145492 0.9047409896304788 1.0 1.0 2 P30154 1 +Acanthocytosis 0.3062648917708988 0.1186958694589852 0.9055163091082798 1.0 1.0 4 O14656 1 +Abnormality of the abdominal wall 0.3119100697648019 0.1184945292695951 0.905675829569416 1.0 1.0 116 P04066,Q15643,Q9BXW9,Q9ULC3,Q14739,Q9UBM7,Q15056,Q10713,O00754,O75844,P16278,Q32P28 12 +Contractures of the joints of the lower limbs 0.3035047833797991 0.1184437317498301 0.9057160766999272 1.0 1.0 56 Q8IZA0,Q8IWS0,Q8TD16,Q7LGA3,P27635,Q14118,P63241,P37268,Q86XL3,O00459,P06753,Q99720,Q08J23 13 +Sparse scalp hair 0.3080905411854396 0.1177370719446856 0.9062759918892288 1.0 1.0 34 Q14574 1 +Uterus didelphys 0.3921568627451139 0.1168233450180779 0.9070000437703476 1.0 1.0 2 O14974 1 +Tricuspid valve prolapse 0.3836552748885607 0.1162438966109894 0.9074592480753358 1.0 1.0 3 Q9NX14,P53701 2 +Subglottic stenosis 0.3836552748885605 0.1162438966109894 0.9074592480753358 1.0 1.0 3 Q7Z2Z2,Q9UHB7 2 +Ovarian carcinoma 0.3824665676077287 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q8WX93,P42771 2 +Functional intestinal obstruction 0.3824665676077287 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q8WX93,P42771 2 +Choriocarcinoma 0.3824665676077285 0.1156625168809366 0.9079200140117194 1.0 1.0 3 O96017,P42771 2 +Extrahepatic cholestasis 0.3824665676077287 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q8WX93,P42771 2 +Peritoneal abscess 0.3824665676077287 0.1156625168809366 0.9079200140117194 1.0 1.0 3 Q8WX93,P42771 2 +Fatigable weakness of swallowing muscles 0.2958850930369977 0.1150871146344236 0.9083760730700728 1.0 1.0 14 Q9UQN3,Q14203,Q96PY6,Q99700 4 +Aplasia hypoplasia involving the musculature of the upper limbs 0.3835412953060141 0.1135075609574948 0.909628169046488 1.0 1.0 2 Q9Y5S9 1 +Increased density of long bones 0.3835412953060078 0.1135075609574925 0.9096281690464898 1.0 1.0 2 Q13126 1 +Hyperaldosteronism 0.3823529411764774 0.1130874525881129 0.9099612225598674 1.0 1.0 2 Q01968 1 +Abnormality of mouth size 0.3159097989663714 0.1130547061186415 0.909987183971477 1.0 1.0 122 P11166,P04062,P15586,Q7LGA3,Q9UBM7,P49459,O00459,O75844,P16278,Q15392,Q01105,Q9NX62 12 +Vitreous hemorrhage 0.2906008328375884 0.1120930378643631 0.9107496376156844 1.0 1.0 6 P29992,O15484,P06400,Q92560,P35222 5 +Hand clenching 0.2969532468045896 0.1116779761579516 0.9110787425523212 1.0 1.0 8 Q8TD16,O14656 2 +Abnormal b cell subset distribution 0.3735225270246248 0.1115983703709409 0.9111418642074148 1.0 1.0 3 P17812 1 +Short chin 0.2899228437329752 0.110681534913873 0.91186888900633 1.0 1.0 11 Q08J23,O75844 2 +Joint hemorrhage 0.3740344622697676 0.110382622748383 0.912105933946181 1.0 1.0 2 P49257 1 +Blistering by anatomical location 0.364635958395247 0.1080730736593912 0.9139377271360504 1.0 1.0 3 Q9H4L7,P23229 2 +Oral mucosal blisters 0.3645276292335239 0.1077596812035054 0.914186326328044 1.0 1.0 2 P23229 1 +Aplasia hypoplasia of the bladder 0.3645276292335239 0.1077596812035054 0.914186326328044 1.0 1.0 2 P23229 1 +Axillary pterygium 0.3645276292335239 0.1077596812035054 0.914186326328044 1.0 1.0 2 P23229 1 +Hypoplastic dermoepidermal hemidesmosomes 0.3645276292335239 0.1077596812035054 0.914186326328044 1.0 1.0 2 P23229 1 +Blistering by histological location 0.3645276292335239 0.1077596812035054 0.914186326328044 1.0 1.0 2 P23229 1 +Acral blistering 0.3645276292335189 0.1077596812035043 0.914186326328045 1.0 1.0 2 Q9H4L7 1 +Hamartomatous polyposis 0.3619613670133748 0.1071058319572738 0.914705020552006 1.0 1.0 3 P20585,Q15437 2 +Bone cyst 0.3618538324420777 0.1071043974308878 0.9147061585921884 1.0 1.0 2 Q15437 1 +Follicular thyroid carcinoma 0.3618538324420777 0.1071043974308878 0.9147061585921884 1.0 1.0 2 Q15437 1 +Conjunctival hamartoma 0.3618538324420777 0.1071043974308878 0.9147061585921884 1.0 1.0 2 Q15437 1 +Abnormal placental membrane morphology 0.3615567439096925 0.1070336992566203 0.9147622451686706 1.0 1.0 2 Q9H4L7 1 +Severe hearing impairment 0.3615567439096926 0.1070336992566203 0.9147622451686706 1.0 1.0 2 Q06124 1 +Cleft soft palate 0.3021271183946735 0.1067677474310241 0.91497323500172 1.0 1.0 59 O75312,P62913,P78318,P60866,P62266,O43505,Q96PY6,Q14118,Q9Y619,Q15392 10 +Hydranencephaly 0.3586924219910867 0.1059797000090982 0.9155984585139534 1.0 1.0 3 Q92917,Q53EZ4 2 +Staring gaze 0.3550207961972744 0.1055805521004846 0.9159151556687936 1.0 1.0 2 P42858 1 +Choking episodes 0.3550207961972744 0.1055805521004846 0.9159151556687936 1.0 1.0 2 P42858 1 +Aqueductal stenosis 0.2818073721759748 0.1055096251727393 0.915971432837554 1.0 1.0 4 Q15427,P57740,P57081 3 +Cutaneous syndactyly of toes 0.3567458267947899 0.1053376042122799 0.9161079250975092 1.0 1.0 3 P27635 1 +Hypoplasia of teeth 0.3027600574550558 0.1052654517096423 0.916165176172103 1.0 1.0 21 P04080,O75844 2 +Reticular hyperpigmentation 0.3475935828877144 0.1041509243527406 0.9170495787755432 1.0 1.0 2 P09884 1 +Long eyelashes 0.3028234727634499 0.1038529780797516 0.9172860233017764 1.0 1.0 40 O94992,P62266,Q5KU26,Q9Y619,Q4J6C6 5 +Fibrosarcoma 0.3446226975638829 0.1036397088749828 0.9174552742024672 1.0 1.0 2 Q13126 1 +Atrophy degeneration involving the corticospinal tracts 0.2913330904916986 0.1036035374749356 0.9174839802747888 1.0 1.0 13 Q15056,O00400 2 +Abnormality of urinary uric acid concentration 0.3480432242265914 0.1027143639296884 0.9181896731773628 1.0 1.0 3 P00492 1 +Spontaneous abortion 0.3473997028231819 0.1025357725260475 0.9183314200995064 1.0 1.0 3 P50570,Q8NCE2 2 +Fatigable weakness of respiratory muscles 0.2943412183472726 0.1023452280930398 0.9184826569311052 1.0 1.0 15 Q9UQN3,Q14203,Q96PY6,Q99700 4 +T cell lymphoma 0.2728894173602768 0.1019164387046076 0.9188230017063096 1.0 1.0 4 P49327,Q07864,P52701 3 +Anotia 0.3449032190749475 0.1018620922269888 0.918866139424148 1.0 1.0 3 Q9Y619 1 +Bronchomalacia 0.3420505200594371 0.1011286801848831 0.919448311253461 1.0 1.0 3 O75369,P63000 2 +Prominent veins on trunk 0.3396731054977732 0.1005461945913985 0.9199107106405656 1.0 1.0 3 P36543,Q9Y487 2 +Abnormal subcutaneous fat tissue distribution 0.3396731054977731 0.1005461945913985 0.9199107106405656 1.0 1.0 3 P36543,Q9Y487 2 +Abnormal circulating apolipoprotein concentration 0.3396731054977732 0.1005461945913985 0.9199107106405656 1.0 1.0 3 P36543,Q9Y487 2 +Abnormal cutaneous elastic fiber morphology 0.3396731054977732 0.1005461945913985 0.9199107106405656 1.0 1.0 3 P36543,Q9Y487 2 +Abnormality of amino acid metabolism 0.3095662507427306 0.0996593639853287 0.920614762714292 1.0 1.0 2 P18074 1 +Lipoma 0.2699673770489755 0.0993219080613803 0.9208826843022369 1.0 1.0 5 P27635 1 +Thyroiditis 0.2782238688838489 0.0980157943954882 0.9219197516443962 1.0 1.0 6 Q96J02,P50851 2 +Abnormality of thalamus morphology 0.2980792232693657 0.0971850990008865 0.9225794013005748 1.0 1.0 19 P02792 1 +Aplasia hypoplasia of the eyelid 0.2870043812237117 0.0970117869130409 0.9227170339998814 1.0 1.0 12 Q9Y3Z3,P63241 2 +Abnormal circulating bilirubin concentration 0.3027810898894262 0.0959082738512786 0.9235934232929068 1.0 1.0 29 P49459,P43034,Q14739,P11166 4 +Scaphocephaly 0.310846953937595 0.0952793597765506 0.9240929365724124 1.0 1.0 3 P48444,P40855 2 +Numerous pigmented freckles 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Tiger tail banding 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Increased mean corpuscular hemoglobin concentration 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Concave nail 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Abnormal mean corpuscular hemoglobin concentration 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Low set nipples 0.3096582466567627 0.0951232196439493 0.9242169550904548 1.0 1.0 3 P26639,P18074 2 +Alacrima 0.2619684805233488 0.0943801628123602 0.9248071732403856 1.0 1.0 5 Q7Z392,O95163,Q03001,P55011 4 +Polygenic inheritance 0.2730517549077825 0.092770862344359 0.9260855996380016 1.0 1.0 6 P04637,P50454,P35658,P11274,Q07812 5 +Genetic anticipation 0.2841010401188729 0.0926333351827899 0.926194859952707 1.0 1.0 3 Q9UBB4,Q99700 2 +Hypoplasia of the ear cartilage 0.2817236255572087 0.0924724390826052 0.926322687803627 1.0 1.0 3 P57740,P57081 2 +Olivopontocerebellar hypoplasia 0.2665676077265996 0.0916588600341594 0.9269690846774028 1.0 1.0 3 P30153,Q99700 2 +Multiple enchondromatosis 0.2710267967806191 0.0908166295722315 0.9276382961679586 1.0 1.0 6 O75874,O15160 2 +Centrally nucleated skeletal muscle fibers 0.2835785793997329 0.0900407083500756 0.9282548656051656 1.0 1.0 10 P06753,Q9H173,P51114,Q8NCE2 4 +Early onset of sexual maturation 0.2973355684201547 0.0891047013983294 0.928998701084121 1.0 1.0 43 Q13423,Q7LGA3,O75874,Q9ULC3,Q9UBM7,P63241,Q15056,O00170 8 +Wide intermamillary distance 0.2988031590841248 0.0886188730053576 0.9293848086078856 1.0 1.0 21 P49459,Q9BZH6,Q9UBM7 3 +Asymmetric growth 0.2827980859760949 0.0852018802360918 0.932100895806691 1.0 1.0 9 P28482,Q9Y6K9,P07437 3 +Morphological abnormality of the pyramidal tract 0.2997891015348686 0.0849104851114253 0.9323325559804658 1.0 1.0 23 Q15056,Q9Y619,O00400,O95831,P11166 5 +Cerebellar malformation 0.2992271513660346 0.0834571272626615 0.93348806590578 1.0 1.0 59 Q96J42,O43505,Q9UBM7,Q14118,P07437,Q15056,Q04721,O00754,Q15043 9 +Decreased lacrimation 0.2620464009518065 0.0828027314815225 0.9340083971804513 1.0 1.0 6 P55011,Q7Z392,O95163,Q10567,Q03001 5 +Abnormal aggressive impulsive or violent behavior 0.3029279304952428 0.0817262749513994 0.9348643838562758 1.0 1.0 109 P19022,P54802,O75503,Q9UBM7,P67870,Q8NB90,P49459,Q10713,P49768,Q8ND04,Q01105,Q9NUM4,P11166 13 +Generalized hypopigmentation 0.2785572311816996 0.0779095296451627 0.9379000188942964 1.0 1.0 9 O75312,O00203,Q01968 3 +Neoplasm of the liver 0.3007218143579179 0.0757061801103472 0.9396528590900024 1.0 1.0 36 Q10713,P11717 2 +Cerebellar atrophy 0.327949129436791 0.075628197407836 0.9397149024145972 1.0 1.0 144 Q14108,O75312,O14773,P51798,Q9H173,Q8IV08,O75503,Q8N0X7,Q06787,P07437,Q10713,O00400,O00754,O15121,P18887,Q15043 16 +Hypoplasia of penis 0.3015075882288281 0.0752219313394793 0.9400381351012856 1.0 1.0 108 O75312,P42892,P19022,Q9BZH6,Q9BXW9,O43505,Q9UBM7,Q96PY6,Q15056,Q14118,P49459,Q10713,Q9H0U9,Q9Y3Z3,P43034,Q9Y6N7 16 +Autoimmune antibody positivity 0.2768681155105636 0.0750981747966441 0.940136600027072 1.0 1.0 9 P49327,Q13546,P53621,P22314,O95394,P61011,Q96J02,P42224 8 +Neoplasm of striated muscle 0.2732142857142876 0.0749744127753492 0.9402350702268952 1.0 1.0 8 P04637,Q15645,O60566,P42771,O43684,O96017,Q9UPY3 7 +Rhabdomyosarcoma 0.2732142857142876 0.0749744127753492 0.9402350702268952 1.0 1.0 8 P04637,Q15645,O60566,P42771,O43684,O96017,Q9UPY3 7 +Broad forehead 0.2964596598932891 0.0747361424711399 0.9404246505398676 1.0 1.0 42 P19022,P55201,P78318,P27635,Q2M1P5,Q15056,O00170,O00754,Q04721,Q8NCH0 10 +Alopecia 0.2939247800326602 0.0745892856287211 0.9405414992050058 1.0 1.0 44 P01889,P04080,P02792,Q9Y6K9,O75844 5 +Retrognathia 0.2858576698515499 0.0712853452684519 0.9431706583377508 1.0 1.0 85 P04062,Q7LGA3,Q8NB90,O75844,Q15392,Q4J6C6 6 +Aplastic anemia 0.2732956236975223 0.0693261359574292 0.9447300222955048 1.0 1.0 9 Q9NPE3,Q7Z2Z2,O76094,Q9H1A4,P61011,Q9Y3A5,Q9NX24,Q5F1R6 8 +Gastrostomy tube feeding in infancy 0.2988735046588473 0.0691468388048466 0.944872738246787 1.0 1.0 38 P67870,Q8NB90,O15121,Q99720,Q01105,Q96J02 6 +Shawl scrotum 0.2425223287162458 0.068813793147008 0.9451378387713336 1.0 1.0 6 Q9Y619 1 +Chronic lung disease 0.2712116701399178 0.0660677352528469 0.9473238982459948 1.0 1.0 9 Q8N3U4,Q13546,Q14683,Q9UHB7,P50454,P50851,P54132,Q96J02 8 +Posterior embryotoxon 0.2913995560154591 0.0646734858218068 0.9484339738631362 1.0 1.0 20 Q15056,Q7LGA3 2 +Aplasia hypoplasia of the nipples 0.287438242332813 0.0608581594050066 0.9514721716047556 1.0 1.0 18 P10586,Q9Y6K9 2 +Cerebral hypoplasia 0.27588585421081 0.0581000676291555 0.9536689205254922 1.0 1.0 14 P35606,Q9UBM7 2 +Radial deviation of the hand or of fingers of the hand 0.2659321024419248 0.0580157856674846 0.9537360545609316 1.0 1.0 10 P46100,Q15427,P38919,O75369,Q02750,Q06124,O43175,P21333,P41227 9 +Hypoventilation 0.2758025967805566 0.0578832006583551 0.953841664616802 1.0 1.0 14 P11047,P06753 2 +Abnormal circulating androgen level 0.2794470145856849 0.0576513127080478 0.9540263759784416 1.0 1.0 15 Q13423 1 +Serositis 0.2894295715896862 0.0571353272734657 0.9544373952805816 1.0 1.0 20 P01889 1 +Abnormality of the tarsal bones 0.2935688635986121 0.0546820549252916 0.9563917660648992 1.0 1.0 24 Q9UPT5,O14656,Q14739,O75787,O75844,P98175,P18074 7 +Abnormality of the nasolabial region 0.2402085095431084 0.0534195133572577 0.9573976579987618 1.0 1.0 7 O14656,Q8NCH0 2 +Abnormality of peripheral nerves 0.2922350744360554 0.051769239947854 0.9587125656379714 1.0 1.0 47 P04792,Q99720,Q6UWE0,Q9Y619,O15121,Q92734,P07602,O95831 8 +Abnormality of urine homeostasis 0.3577688178921471 0.0508917818667883 0.9594117541457884 1.0 1.0 198 Q14108,Q6YHK3,P01889,P04066,P04062,P15586,P54802,Q13423,P06280,P10253,O43772,O00754,P16278,Q9NPF0 14 +Abnormality of the inner ear 0.2604634393101407 0.0493410173238506 0.9606475322103292 1.0 1.0 10 P10644 1 +Intermittent diarrhea 0.2511904761904787 0.0492896654258805 0.9606884553040738 1.0 1.0 8 P46100,P04637,Q9UER7,P42771,Q4G176,Q8WX93,Q9H9E3 7 +Tics 0.2335614400476127 0.0490962326490418 0.960842605699306 1.0 1.0 7 P46109,P28482,Q8WXI9,Q01082,P11274,Q9UHX1 6 +Unsteady gait 0.293664453810849 0.0484497186051662 0.961357836083876 1.0 1.0 52 O75503,Q14118,Q10713,O95831,P11166 5 +Retinal hemorrhage 0.2301497328704704 0.0470732343462716 0.9624548595795774 1.0 1.0 7 Q9Y6K9,Q9Y487 2 +Heterotaxy 0.2270157691163375 0.045327036743749 0.9638466373754098 1.0 1.0 7 Q7LBC6,O96028,Q9H3P2,P24468,Q5H8A4,Q13363 6 +High myopia 0.2550827467849584 0.0435058975688645 0.9652982633989884 1.0 1.0 9 Q9Y487,P27635,Q14118 3 +Hypophosphatemia 0.2226418595122201 0.04306258390142 0.96565164533681 1.0 1.0 7 P53680,Q01968,P51798 3 +Vascular dilatation 0.2925093851971124 0.0409276830194788 0.967353548074197 1.0 1.0 69 P01889,Q7LGA3,Q06787,Q15056,P10253,Q9Y3Z3,O75844,Q96PU5,P06753,P10644 10 +Enchondroma 0.2529523657693791 0.0408697501397226 0.9673997331813232 1.0 1.0 9 O75874 1 +Limb undergrowth 0.2924817755551818 0.0396960645650199 0.9683354392278742 1.0 1.0 52 Q15643,Q9BXW9,Q14739,Q9UBM7,Q96PY6,Q15392,P10644 7 +Hyperlordosis 0.2927072357171424 0.0392822534425197 0.9686653553963512 1.0 1.0 53 P04066,Q14118,Q15056,P16278,P06753 5 +Abnormal emotion affect behavior 0.3757491996098886 0.0379332065233891 0.9697409371168072 1.0 1.0 241 O75503,Q9UBM7,P67870,Q5KU26,O00170,P50897,P07602,P06865,P54802,Q0IIM8,Q9NR50,P49459,O43772,P49768,P17900,O94992,P19022,Q13510,Q8NBF2,Q8N0X7,P02792,Q06787,Q10713,Q8ND04,Q9NUM4,O95831,P11166,P10644,P01889,P04062,Q96PY6,Q8NB90,O43678,Q01105 34 +Partial duplication of the phalanx of hand 0.2858071976484386 0.0369090466425014 0.9705575264860188 1.0 1.0 21 P62273,Q9BXW9,P62913,P42766,P60866,Q2M1P5,P08708,P46783 8 +Abnormal uvula morphology 0.2915895603878054 0.0359335043990716 0.9713353804632372 1.0 1.0 41 Q9BXW9,P78318,P62266,O43505,Q14118,Q9Y619,Q15392 7 +Generalized limb muscle atrophy 0.2358661162772566 0.0357626737622998 0.9714715960382094 1.0 1.0 8 P06753,P49589 2 +Abnormality of the shoulder girdle musculature 0.2938748003722276 0.0355931546192569 0.9716067666873828 1.0 1.0 34 P11047,P06753,P07602 3 +Abnormal incisor morphology 0.2811690961623541 0.0344477472867089 0.972520109215952 1.0 1.0 19 Q7LGA3,Q9Y6K9,Q96PY6 3 +Hemiparesis 0.2794997173452698 0.0341545604101194 0.9727539009208586 1.0 1.0 18 P01889 1 +Thin skin 0.2897711393432109 0.0338355982440481 0.9730082488945204 1.0 1.0 28 Q06787,O00170,O75844,Q96PU5,P10644 5 +Abnormality of the neck 0.3443047354087391 0.0301311041081781 0.9759624944960072 1.0 1.0 177 P19022,Q15643,Q07954,O96000,P15586,Q7LGA3,Q9ULC3,Q14739,Q9UBM7,Q15056,P49459,O00754,P16278,O75844,O95831,Q99720,Q9NUM4,P11166 18 +Periorbital edema 0.2886506075215792 0.028659123924734 0.977136457348024 1.0 1.0 26 Q15056,O00170,P28070 3 +Abnormal talus morphology 0.2769946459371152 0.0260893009992821 0.9791861107252466 1.0 1.0 18 Q9UPT5,O14656,O75844,P98175,P18074 5 +Abnormal shape of the occiput 0.2912444925066522 0.0251098853943915 0.979967315264874 1.0 1.0 32 Q2M1P5,P62266,O00754,Q04721 4 +Abnormality of the antihelix 0.2524608610880631 0.0247676190315064 0.9802403194006866 1.0 1.0 12 P98175,Q9H2M9,Q08J23,P27635 4 +Osteoporosis 0.2902247294828651 0.0215134790067982 0.982836051259298 1.0 1.0 69 Q15643,Q13510,Q9BZH6,O00170,P16278,P10644 6 +Glossoptosis 0.2112469825831542 0.020449782630576 0.9836845713432144 1.0 1.0 8 P98175,O15160 2 +Papilledema 0.2813939278705317 0.0204360712932869 0.9836955091217848 1.0 1.0 21 P04062 1 +Axonal loss 0.2000000000000024 0.0156650743825019 0.9875015901820838 1.0 1.0 8 Q9NX46,P17480,P35251,O95817,Q8N9N2,Q27J81,Q15650 7 +Tremor 0.3429000683635215 0.0156212317016806 0.9875365673003562 1.0 1.0 177 Q14108,O43924,O14773,Q13510,Q99720,P04062,Q9BZH6,P04080,O75503,P02792,Q15056,Q10713,O95831,P07602,Q9NUM4,Q15043,P11166 17 +Abnormality of muscle size 0.3542818716427704 0.0142994988980921 0.9885910394124606 1.0 1.0 198 Q7LGA3,O00170,O00400,P04066,Q9H173,P13473,P10253,O00754,P16278,Q13510,P11047,Q10713,P07686,O00459,Q99720,O95831,P10644,O43505,Q96PY6,Q15056 20 +Abnormal nerve conduction velocity 0.2854047332849723 0.0113126469926972 0.9909740061415292 1.0 1.0 45 P04792,Q99720,Q6UWE0,Q9Y619,O15121,P07602,O95831 7 +Abnormality iris morphology 0.2797896810668049 0.0109746793586565 0.9912436485547153 1.0 1.0 85 Q9BXW9,P78318,Q7LGA3,Q9P273,O43505,Q9UBM7,P11047,Q15056,Q10713,P10644 10 +Truncus arteriosus 0.2216044441856951 0.0106110737654922 0.9915337469454052 1.0 1.0 9 Q9UHX1,P11274 2 +Vertebral fusion 0.2272185824895745 0.008633650930681 0.9931114287980888 1.0 1.0 10 Q9Y2W2,O75369,O96028,Q9UHB7,Q9NVI1,Q9Y5S9,Q9UHX1,P21333,Q13363 9 +Patellar dislocation 0.275929172066019 0.0084307539406783 0.993273311281061 1.0 1.0 20 Q96PU5,Q9NX62 2 +Abnormality of fluid regulation 0.3337584382938498 0.0083007528088847 0.9933770335473252 1.0 1.0 163 Q14108,P01889,Q13510,P04062,Q15643,O96000,P28070,Q14739,Q9UBM7,P06280,P10619,O00170,P11047,Q96PY6,Q15056,P16278,P04439,P10644 18 +Abnormal aortic morphology 0.2963292065654609 0.0067878895061169 0.9945840893527468 1.0 1.0 110 P01889,P19022,P04062,Q9BXW9,P62913,P01130,Q7LGA3,Q9UBM7,Q06787,Q15056,Q9Y3Z3,O00459,O75844,Q96PU5,P06753 15 +Glioma 0.2529740735671189 0.0049675283439139 0.996036502129816 1.0 1.0 14 P60866,O75874,P43246,P42771,P52701 5 +Abnormality of dental structure 0.2854073931902367 0.0047227978776873 0.9962317664979008 1.0 1.0 76 Q15643,P51798,P04080,Q9UBM7,Q96PY6,Q15056,Q9Y6K9,P16278,O75844 9 +Papilloma 0.2380810488677002 0.0024983769896461 0.9980065856466744 1.0 1.0 12 P04637,P21912,P20585,Q8IWT6,Q15437,Q9Y6K9,P19447,P29144,P18074,P16615,Q99828 11 +Abnormal lung development 0.2861104395717042 0.0018982921937944 0.998485382876336 1.0 1.0 49 Q15643,Q14739,Q9UBM7,Q96PY6,O75844 5 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..85aa6a6f4cfebfeab458895631dc4cb5ee4e4472 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal bowman capsule morphology", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Biconvex vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical c2 c3 vertebral fusion", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal autonomic seizure", "Focal aware seizure", "Focal cognitive seizure with deja vu jamais vu", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hippocampal atrophy", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychic epileptic aura", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocerebellar cyst", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spondylometaphyseal dysplasia", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary cusp", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APRT", "ARCN1", "ARFGEF2", "ARHGDIA", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATP1A1", "ATP2A2", "ATP2B4", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "ATXN2", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAP1", "BAX", "BAZ1B", "BCAP31", "BCKDHA", "BCKDHB", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRD4", "BRPF1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALR", "CAMK2G", "CAPN1", "CAPN5", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD109", "CD2AP", "CD320", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDKN2A", "CELF2", "CENPF", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD2", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CIB1", "CISD2", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG2", "COG4", "COG5", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DPAGT1", "DPM1", "DPP9", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHA2", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FAH", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IKBKB", "IKBKG", "IMPA1", "IMPAD1", "INF2", "INPPL1", "INTS1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITGA6", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KIRREL1", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN1B1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MDH1", "MDH2", "MECP2", "MECR", "MED23", "MED25", "MESD", "MFN2", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS14", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK1", "NEK9", "NELFA", "NEMF", "NF2", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NT5C3A", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PKP2", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSEN1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRSL1", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNF213", "RNPC3", "ROBO1", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "SALL2", "SAMHD1", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC44A1", "SLC5A6", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D8B", "TBCD", "TBCE", "TBL2", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIMM50", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM106B", "TMEM126A", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBA5", "UBE2A", "UBE3A", "UBE4A", "UBE4B", "UBIAD1", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR11", "WDR26", "WDR36", "WDR4", "WFS1", "WIPI2", "WNK1", "XPC", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF292", "ZNF687", "ZPR1"], "leading_proteins": ["AARS", "ABCB1", "ABCB6", "ACBD5", "ACP2", "ACSF3", "ACTN1", "ADAM17", "ADPRHL2", "AFF4", "AIFM1", "AIP", "ANAPC1", "ANKLE2", "ANKRD17", "AP1B1", "AP2S1", "AP3B1", "APOL2", "APP", "APRT", "ARCN1", "ARPC1B", "ASAH1", "ASCC1", "ATP2A2", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1E1", "ATRX", "ATXN10", "ATXN2", "AURKA", "B4GAT1", "BAG3", "BAP1", "BAX", "BCR", "BICD2", "BLM", "BRPF1", "BUB1B", "BUB3", "CALR", "CAPN5", "CARS", "CASP8", "CBL", "CCDC22", "CD109", "CD320", "CDC45", "CDH2", "CDKN2A", "CELF2", "CEP290", "CEP55", "CFL2", "CHD8", "CHEK2", "CHMP2B", "CHST14", "CIB1", "CLCN7", "CLN5", "CLTC", "CNNM4", "COG2", "COG4", "COLEC12", "COPA", "COPB2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNB1", "CTPS1", "CTSA", "CTSC", "CWF19L1", "CYFIP2", "DAG1", "DAXX", "DCTN1", "DDX6", "DEGS1", "DGCR8", "DHCR24", "DHCR7", "DIAPH3", "DICER1", "DLG1", "DNAJC21", "DNM1L", "DNM2", "DOCK6", "DSC2", "DSC3", "DSG2", "DST", "DYNC1I2", "DYNLL1", "ECE1", "EEF1A2", "EFL1", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF4A3", "EIF4H", "EIF5A", "ELMO2", "ELP1", "EPHA2", "EPHX2", "ERCC2", "ERCC3", "EWSR1", "EXOC7", "FANCD2", "FANCI", "FASN", "FDFT1", "FH", "FHL1", "FKBP10", "FLNA", "FLNB", "FLNC", "FMR1", "FSCN1", "FTL", "FUCA1", "FXR1", "G6PD", "GAA", "GAL", "GALNT2", "GANAB", "GARS", "GATAD2B", "GBA", "GLA", "GLB1", "GM2A", "GNA11", "GNAI3", "GNS", "GPAA1", "GPKOW", "GPT2", "HCCS", "HEXA", "HEXB", "HEXIM1", "HLA-A", "HLA-B", "HLA-C", "HMGB3", "HNRNPK", "HPRT1", "HPS6", "HS2ST1", "HSPB1", "HTT", "IDH1", "IGBP1", "IGF2R", "IKBKG", "IMPAD1", "INF2", "IRS4", "ITCH", "ITGA6", "KDM3B", "KIAA0319L", "KIDINS220", "KIF1A", "KIF7", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LBR", "LDHA", "LDLR", "LIPA", "LMAN1", "LRBA", "LRIG2", "LRP1", "LRRC8A", "LRSAM1", "MAGED2", "MAN2B1", "MAP2K1", "MAP2K2", "MAPK1", "MCM8", "MIF", "MPG", "MSH2", "MSH3", "MSH6", "MSTO1", "MTAP", "MTMR14", "MTR", "MYH9", "MYO5A", "NAA10", "NAGLU", "NARS", "NCSTN", "NDUFA2", "NDUFB10", "NDUFB11", "NEDD4L", "NEK1", "NEK9", "NELFA", "NEMF", "NHLRC2", "NHP2", "NNT", "NONO", "NOP10", "NOTCH2", "NPC1", "NPC2", "NR2F2", "NSD2", "NSUN2", "NUP107", "NUP214", "NUP88", "OCRL", "P3H1", "PAFAH1B1", "PALLD", "PANX1", "PARN", "PDE6D", "PEX19", "PFKM", "PFN1", "PGM1", "PGM3", "PHF6", "PHGDH", "PIGG", "PIK3R2", "PLD3", "PLEC", "PLOD1", "PLOD3", "PMPCA", "PMVK", "PNPLA6", "POFUT1", "POLA1", "POLD1", "POLE", "POLR1C", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PSAP", "PSAT1", "PSEN1", 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setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 31 49 4.681936668370986 2.8417728510365947e-06 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 4.642352801522984e-37 1.6324596881734863e-24 9.126369935765616e-40 1.5076998302279734e-30 1.4579954179381388e-21 +Cell adhesion molecules cams 12 14 3.0687364014876417 0.0021496617487581 4.043689320388349 9.91019417475728 0.3640395302172229 0.4325707543794381 2.3114392567097153 2.512916721209252 1.1817978240178808 0.3174557953274378 0.0713888723716441 0.2336798458054532 0.0001773541479557 3.659146914367175e-10 1.3219039302405263e-06 +Galactose metabolism 2 13 2.7459200057287902 0.0060341474698837 4.58252427184466 13.216019417475728 -0.1782313827276002 0.4435757909481123 2.9055496675792862 0.5161805957123455 1.1764125997304256 0.3166437961140673 0.0003886260619154 0.0847528009868792 0.0006712136127385 0.0089509329804495 0.0544656750173612 +Other glycan degradation 7 8 2.68768319235083 0.0071949623790825 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 6.90608102767741e-10 3.8887516945815136e-05 2.2898908765267025e-11 2.993782432894179e-10 6.983804903918182e-08 +Ecm receptor interaction 6 9 2.49045767477704 0.0127578690315837 1.6650485436893203 4.555825242718447 0.2096433457400827 0.4422389760138975 1.377503633308977 1.8273249716413784 1.143329174769281 0.3102717144634864 1.0 1.0 0.0690620672163432 0.004165624514577 0.0050026695308212 +Axon guidance 5 27 2.452517082124166 0.0141860643680036 8.555825242718447 23.703883495145632 -0.5599721042699952 0.5024934418739405 4.39376102780521 3.606181917937803 0.90571396816964 0.3154927590117977 0.5340255411649593 1.0 0.6018020784024207 0.026089354764215 0.083221520742866 +Endocytosis 10 55 2.41466170083306 0.0157498303444931 12.91747572815534 50.817961165048544 -0.329352892192332 0.6002469256948284 6.258430076793212 7.535892607816947 0.8450068005539967 0.3196736085380035 0.3665308143614397 0.1795690337818556 0.0683160276894945 0.1859519013031985 0.0816575690086568 +Glycosaminoglycan degradation 4 5 2.408996536850783 0.0159964497695472 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 1.9231390410922443e-06 2.3666612945957126e-05 6.154716163450247e-08 5.744803073006659e-06 0.000160552482799 +Small cell lung cancer 6 15 2.351837920441787 0.0186809128569462 3.684466019417475 11.740291262135925 -0.0428587473816435 0.612223606985984 2.482453268327089 3.400889077448442 0.8074601887401521 0.2924300309032475 1.0 1.0 0.5142525268330266 0.0086869143045309 0.0642903416117007 +Antigen processing and presentation 3 19 2.2093793403091824 0.0271482667937146 5.337378640776699 16.74757281553398 0.2387870946403815 0.5680791453500826 2.8523982282892524 1.5499354612429144 0.9338462051385796 0.3189030666688743 0.2733967462722031 0.1747599807978781 0.006477682080963 0.0146129998399771 0.0396063215160503 +Viral myocarditis 4 14 2.1620897767121403 0.0306112568881622 4.031553398058253 11.228155339805824 0.0319814940949768 0.5543700591424958 2.250452924114055 1.5125313108034515 0.956572263574295 0.3192370987906132 1.0 1.0 0.0532804729840314 0.0133642522995781 0.0359117122080593 +Sphingolipid metabolism 3 12 2.0737653253237447 0.0381011109522371 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 0.0010512986284106 0.1157751708195439 0.0018000470176383 0.002932051876052 0.0063685282240186 +Natural killer cell mediated cytotoxicity 3 17 2.0481072607707693 0.0405494906308494 4.859223300970874 15.269417475728156 0.0010910938828692 0.6578096713542636 2.9270395558972484 2.707009357328761 0.724843022952491 0.2863674189596557 1.0 1.0 0.1367168788611213 0.0774145056148102 0.218372295560768 +Type i diabetes mellitus 2 5 1.9729506284460243 0.0485011875986265 1.7597087378640777 4.854368932038835 0.2295754227924032 0.537404328385132 1.0159064595639915 0.605921700063298 0.9114211067852314 0.3048453574503886 1.0 1.0 0.009201700056446 0.0052676758380378 0.0338099842169397 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d8b83b19685ada237904f157692a1da6159a4bd7 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.27777777777778 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b07c3f22aa7e3899f3dceff32fb9fe859763aa6f --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..26bb3fac045ab68c19c6049d391a7b1396db3533 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,82 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.9415647982308268 4.681936668370986 2.8417728510365947e-06 0.0005113890360292 0.0005115191131867 49 O14773,P15586,O75503,P61916,P06280,Q9UMR5,P11717,P50897,Q99538,P07602,P06865,Q14108,Q99523,P04066,P54802,P13473,Q8NCC3,P10619,P10253,O00754,P16278,P17900,P53634,P11117,Q13510,O15118,P11279,Q15904,O00115,P07686,P38571 31 +Cell adhesion molecules cams 0.9275643069109272 3.0687364014876417 0.0021496617487581 0.3211503509187801 0.1268541519296997 14 P05556,P01889,P19022,P13591,P10586,Q9Y624,Q92859,Q92896,Q13740,P04439,P10321,P06756 12 +Galactose metabolism 0.8706534883650245 2.7459200057287902 0.0060341474698837 0.6635940861683862 0.1295093228234863 13 P10253,P06280 2 +Other glycan degradation 0.9720238095238096 2.68768319235083 0.0071949623790825 0.7274068179789921 0.1295093228234863 8 P04066,Q9BTY2,P07686,O00754,P16278,Q9Y2E5,P06865 7 +Ecm receptor interaction 0.8931754568546632 2.4904576747770397 0.0127578690315837 0.9008568893782014 0.1799600599074069 9 P05556,P07942,P11047,Q08722,Q7L0J3,P06756 6 +Axon guidance 0.684737376493747 2.452517082124166 0.0141860643680036 0.9236003160518732 0.1799600599074069 27 O94813,Q15375,P29317,Q9Y6N7,O14786 5 +Endocytosis 0.579946340499503 2.41466170083306 0.0157498303444931 0.9425897156493552 0.1799600599074069 55 P01889,Q9Y3E7,P09496,P01130,P02786,P04439,P42566,P10321,Q9H4M9,Q96PU5 10 +Glycosaminoglycan degradation 0.9762117157300012 2.408996536850783 0.0159964497695472 0.9451218121398526 0.1799600599074069 5 P15586,P54802,P16278,P06865 4 +Small cell lung cancer 0.7566241272988269 2.351837920441787 0.0186809128569462 0.966438272213492 0.1977979008382548 15 P05556,P07942,Q13309,P11047,O00459,P06756 6 +Antigen processing and presentation 0.6901167974476946 2.2093793403091824 0.0271482667937146 0.992946604227372 0.262655265861289 19 P04439,Q99538,P01889 3 +Viral myocarditis 0.7249545778401563 2.1620897767121403 0.0306112568881622 0.9962877689238584 0.262655265861289 14 P04439,P01889,P78310,P10321 4 +Glycosphingolipid biosynthesis ganglio series 0.9568965517241368 2.128689945736516 0.0332799212276035 0.9977398720989984 0.262655265861289 4 P07686,P16278,P06865 3 +Autoimmune thyroid disease 0.9512578507468435 2.108118944924114 0.0350207021148385 0.9983660478248758 0.262655265861289 4 P04439,P01889 2 +Allograft rejection 0.9512578507468435 2.108118944924114 0.0350207021148385 0.9983660478248758 0.262655265861289 4 P04439,P01889 2 +Graft versus host disease 0.9512578507468435 2.108118944924114 0.0350207021148385 0.9983660478248758 0.262655265861289 4 P04439,P01889 2 +Sphingolipid metabolism 0.733868476495486 2.0737653253237447 0.0381011109522371 0.9990810409358007 0.2703299375389963 12 Q13510,P16278,P06280 3 +Natural killer cell mediated cytotoxicity 0.6771088579562528 2.0481072607707693 0.0405494906308494 0.9994191499968084 0.2703299375389963 17 P04439,P01889,P10321 3 +Renin angiotensin system 0.9209771033237096 1.9969882539899515 0.0458264589904298 0.9997847582509206 0.2751058758507723 4 Q9UIQ6 1 +Type i diabetes mellitus 0.8592238218729739 1.9729506284460243 0.0485011875986265 0.9998701370985678 0.281619798959767 5 P04439,P01889 2 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.6410564973450184 1.9046896643240752 0.0568204233183122 0.9999732705600098 0.3099295817362488 18 P05556,Q14126,P19022,Q02487,P06756 5 +Steroid biosynthesis 0.6943424368037965 1.8378649125169904 0.0660823135432147 0.9999954757351514 0.3280941489599634 11 Q16850,P38571,Q15392 3 +Renal cell carcinoma 0.6102832342849264 1.783445171726632 0.0745138655892159 0.9999991157298184 0.3280941489599634 19 Q15369,P28482,P63000,Q02750,Q13617,P62993,Q16512,Q06124,P36507,O00459,P46108,Q13177,P27361,P11166 14 +Amino sugar and nucleotide sugar metabolism 0.6004320764714632 1.750483251938591 0.0800349616177482 0.9999996988116606 0.3350300718882485 20 P06865 1 +Pathways in cancer 0.4878646079202779 1.7224218484662004 0.0849931286627669 0.9999998861366434 0.3392929837008412 59 P62993,Q9Y6K9,P42771,P05556,Q13617,Q07812,P06753,P08238,P63000,Q02750,Q13309,P07900,P11047,O00459,P11233,P11166,P06756,P28482,Q16204,P07942,P46108,Q92734,P11274 23 +Glycosphingolipid biosynthesis globo series 0.975631500742942 1.7130235511499157 0.0867082069457705 0.9999999187693538 0.3392929837008412 3 P06865,P06280 2 +Epithelial cell signaling in helicobacter pylori infection 0.5732467683979205 1.6672983383705158 0.0954550968970735 0.9999999856310992 0.3520723799775374 23 Q9Y624,Q15904,Q9Y6K9,Q93050 4 +O glycan biosynthesis 0.945412131189128 1.604424843368764 0.1086204385528746 0.9999999989736844 0.3620681285095821 3 O43505 1 +Notch signaling pathway 0.6614521487947851 1.5238849602244449 0.1275374510873939 0.9999999999784016 0.4173952944678345 9 P49768,P78536,Q92542 3 +Prion diseases 0.6275655575015944 1.4499136846186167 0.1470825907306365 0.9999999999996342 0.46001481481016 10 Q02750,P13591,Q07812,P11047 4 +Gap junction 0.5554928796270462 1.442322386716769 0.1492114476102739 0.9999999999997669 0.46001481481016 18 P28482,P04350,P63096,Q02750,Q9BUF5,P06493,P07437,P62993,Q13885,P36507,P27361 11 +Dilated cardiomyopathy 0.5979851420651051 1.4367725458028695 0.1507826337433302 0.9999999999998328 0.46001481481016 12 P05556,P06753,P06756,Q14118 4 +Hypertrophic cardiomyopathy hcm 0.5933365366341433 1.4143692154988905 0.157253523944145 0.9999999999999578 0.4640267919663296 12 P05556,P67936,Q14118,P06753,P06756 5 +Dorso ventral axis formation 0.6978887897710181 1.3442967265062282 0.1788524537044908 0.9999999999999996 0.5093329603771005 5 Q02750,P28482,P62993,Q04721 4 +Non small cell lung cancer 0.5706825195033949 1.3048131458861665 0.1919564816810757 1.0 0.5093329603771005 12 P28482,Q02750,P06400,P62993,P36507,O00459,P42771 7 +Base excision repair 0.5241702612087339 1.3024317650552677 0.1927688296966048 1.0 0.5093329603771005 19 P09429,P49005,Q9NRF9,P29372,P13051 5 +Focal adhesion 0.4632836290321724 1.2637593299273542 0.2063164228106502 1.0 0.5160080290079562 38 P05556,P28482,P63000,Q02750,Q13418,P07942,P62993,Q16512,P11047,P46108,O00459,Q13177,P06756 13 +T cell receptor signaling pathway 0.5143013707683401 1.260991811468255 0.2073117973925722 1.0 0.5160080290079562 20 P28482,Q12959,Q02750,P62993,Q16512,Q9Y6K9,P36507,O00459,Q13177,Q04206 10 +Melanoma 0.600500594923556 1.2555754886358763 0.2092699228754488 1.0 0.5160080290079562 9 P28482,Q02750,P06400,P36507,O00459,P42771 6 +Aldosterone regulated sodium reabsorption 0.5969805737072231 1.1656580216496406 0.2437527388663438 1.0 0.5714475969439384 8 O00459 1 +Regulation of actin cytoskeleton 0.4229156347738628 1.13960303735331 0.2544517193707287 1.0 0.5714475969439384 55 P15311,P07737,Q16512,O43707,P23528,P05556,P35579,Q9UBI6,O15143,Q9NSV4,Q02750,P63000,Q86VI3,Q9Y6W5,O00459,Q13177,P06756,P35080,P28482,P46108,Q9UQB8 21 +Colorectal cancer 0.5360257151357589 1.1364362648246806 0.2557740255887515 1.0 0.5714475969439384 12 P28482,P63000,Q02750,P43246,O00459,Q07812 6 +Erbb signaling pathway 0.503472316150924 1.124449646752653 0.2608223204737423 1.0 0.5714475969439384 17 P28482,Q02750,P46108,P62993,Q16512,P36507,O00459,Q13177,P27361 9 +Arachidonic acid metabolism 0.6341236969734533 1.0929871499840298 0.2743994417347215 1.0 0.5714475969439384 5 P34913 1 +Leukocyte transendothelial migration 0.4759133893562211 1.08325841815358 0.2786937364362019 1.0 0.5714475969439384 23 P05556,Q9Y624 2 +Pathogenic escherichia coli infection 0.4706818261507587 1.0202969052249995 0.3075876706361493 1.0 0.6149357437298675 21 P05556,P04350,Q14247,P63104,P15311,Q9BUF5,P07437,Q13885,O15143,P19338 10 +Leishmania infection 0.5757714430226643 1.0090618697434206 0.3129449632437528 1.0 0.6149357437298675 7 P05556,P28482,P49006,Q04206 4 +Prostate cancer 0.4773311537205429 1.0062392590884324 0.31430049123971 1.0 0.6149357437298675 18 P28482,Q02750,P07900,P06400,P62993,P36507,O00459,Q9Y6K9,P08238,Q04206 10 +Pancreatic cancer 0.4783159352352756 0.9640105461736136 0.3350406385142586 1.0 0.6234381157340018 16 P28482,P63000,Q02750,P06400,Q9Y6K9,O00459,P42771,P11233 8 +Proteasome 0.4275718422329614 0.9621436366716126 0.33597745701857 1.0 0.6234381157340018 36 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,P25786,P28072,Q92530,P60900,P49721,P55036 14 +Endometrial cancer 0.5045818660387058 0.9508920312046668 0.3416591874621995 1.0 0.6234381157340018 11 P28482,Q13418,Q02750,P62993,P36507,O00459 6 +Ether lipid metabolism 0.5729618038278326 0.9506744835351426 0.3417696451180627 1.0 0.6234381157340018 6 Q7L5N7 1 +Bladder cancer 0.5459701106474156 0.948468574524244 0.342890963653701 1.0 0.6234381157340018 8 P28482,Q02750,P06400,P36507,P42771 5 +Thyroid cancer 0.5002758124059694 0.8701162046412836 0.3842369028753749 1.0 0.6743003286484623 10 P28482,Q16204,Q02750,P36507,Q92734,P06753 6 +Glioma 0.4654867080433543 0.861403915434269 0.3890156203317332 1.0 0.6743003286484623 14 P28482,Q02750,P06400,P62993,P36507,O00459,P42771 7 +Chronic myeloid leukemia 0.4413691680579755 0.8588832271830676 0.3904049440243167 1.0 0.6743003286484623 22 P28482,Q02750,Q06124,P62993,P06400,P46108,Q9Y6K9,P42771,P36507,O00459,P11274,Q04206,P27361 13 +Ubiquitin mediated proteolysis 0.3925306137287004 0.8565654530058961 0.3916850852253564 1.0 0.6743003286484623 47 O15344,Q12834,P63208,P46934,Q16763,Q15369,P61088,Q13617,P49459,Q13356,Q9UBT2,P68036,Q13309,Q05086,Q96PU5,Q9UNE7,P29372,Q96J02,Q9C0C9,Q8TBC4 20 +Drug metabolism other enzymes 0.525749084647929 0.8065288146976529 0.4199380004030084 1.0 0.6998966673383474 7 Q9BZX2 1 +Vibrio cholerae infection 0.4286933850548799 0.7952919981654923 0.4264436671162175 1.0 0.7039064934780387 23 Q15904,O43731 2 +B cell receptor signaling pathway 0.4495950172122619 0.7808031873669036 0.4349182591175677 1.0 0.7039064934780387 14 P28482,P63000,Q02750,P62993,P36507,O00459,Q9Y6K9,Q04206 8 +Fc epsilon ri signaling pathway 0.475845035073889 0.761170421547987 0.4465552826951366 1.0 0.7050872884660053 10 P28482,P63000,Q02750,P62993,P36507,O00459 6 +Neurotrophin signaling pathway 0.3944004455704042 0.6791109542546442 0.4970675621827927 1.0 0.7647193264350657 32 Q99523,P28482,P62258,P63104,P63000,Q02750,Q06124,P62993,P27348,P52565,P36507,O00459,Q04917,P46108,Q07812,P49768,Q04206,P27361 18 +Toll like receptor signaling pathway 0.4299658232864369 0.6542866704448467 0.5129271319716329 1.0 0.7693906979574493 13 P28482,P63000,Q02750,P36507,O00459,Q9Y6K9,Q04206 7 +Snare interactions in vesicular transport 0.421883786765696 0.6159941035037586 0.537898411473908 1.0 0.7823027302949515 13 O15400,O15498,Q9UNK0,Q9UEU0,Q86Y82,Q12846,P56962 7 +Glycerophospholipid metabolism 0.4029783097926156 0.5950052391533376 0.5518399689136821 1.0 0.7823027302949515 18 Q8NCC3 1 +Abc transporters 0.4473343184856649 0.5930288962726052 0.5531618139435797 1.0 0.7823027302949515 9 P08183,P33527 2 +Gnrh signaling pathway 0.4169148302560988 0.5104410754908499 0.6097424862335759 1.0 0.8136510915622152 10 P28482,P60953,P29992,Q02750,P17612,P62993,P36507,P27361,P17252 9 +Chemokine signaling pathway 0.3691004002139628 0.4795123034154301 0.6315742176116643 1.0 0.8298055413875882 27 P28482,P63000,Q02750,P63096,Q9UBI6,P62993,Q16512,P46108,Q9Y6K9,O00459 10 +Jak stat signaling pathway 0.435512336109604 0.4683570173113998 0.6395293004208096 1.0 0.8317360679968965 7 O00459 1 +Apoptosis 0.3685088531511438 0.4334806518051776 0.6646656192911395 1.0 0.8545700819457508 22 O00459,O95831,P10644 3 +Vasopressin regulated water reabsorption 0.3700189832897348 0.4224356411281998 0.6727070676514391 1.0 0.8551661162133797 18 Q96FJ2,O43237,P52565,Q9UJW0,Q13561,Q14203,Q12846,Q13409 8 +Tgf beta signaling pathway 0.400992124576614 0.4140884575210488 0.6788093256754542 1.0 0.8551661162133797 9 P28482,Q7Z3T8,P63208,P30154,P27361,P30153 6 +Acute myeloid leukemia 0.3804248911179431 0.4133066338879728 0.6793819701028516 1.0 0.8551661162133797 12 P28482,Q02750,P62993,P36507,O00459,Q9Y6K9,Q04206 7 +Adherens junction 0.3606196238164055 0.3941475797564038 0.6934720847395492 1.0 0.8608618982973715 23 P10586,Q9UQB8,Q92692 3 +Nod like receptor signaling pathway 0.3482356462372397 0.2873734088405811 0.7738264195627227 1.0 0.9040701259890048 12 P08238,P28482,Q9Y6K9,P07900 4 +Alzheimers disease 0.3196048359048873 0.25955042762421 0.7952105790304211 1.0 0.9117063963406102 63 P78536,Q07954,Q92542,O96000,P05067,O43678 6 +Vegf signaling pathway 0.3237161313703646 0.2046697813347364 0.8378301315910028 1.0 0.9544900233315222 13 Q02750,O00459,P04792,P63000 4 +Basal transcription factors 0.2868622417948866 0.1076094181778604 0.9143055257527236 1.0 0.9930783112013544 6 P32780 1 +Phosphatidylinositol signaling system 0.2882101446908731 0.0950731715386268 0.9242567075400084 1.0 0.9930783112013544 13 Q10713 1 +Rig i like receptor signaling pathway 0.2784261564982729 0.0848379881923141 0.9323901921834938 1.0 0.9930783112013544 11 Q13526 1 +Glutathione metabolism 0.2953332693227842 0.0694891829847277 0.9446002425686016 1.0 1.0 22 Q9UJ14 1 +P53 signaling pathway 0.2457810191107904 0.0018900934444107 0.9984919245201516 1.0 1.0 13 Q07812,P06493 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e19707ff94acc84d6fe36b0b37da832d833c8c7f --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP3", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCKDHA", "BCKDHB", "BCR", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBR1", "CCDC12", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CGN", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "COASY", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DNA2", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPAGT1", "DPM1", "DPYSL2", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "EXO1", "EXOC3", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTSE1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "IKBKG", 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0.1499686155438198 0.0412914524019695 0.0458410907711806 0.2160393117631846 +Ecm proteoglycans 6 7 2.3943153543802143 0.0166514251672809 1.308252427184466 3.344660194174758 0.0515483058029464 0.4311087134715219 1.2462097309690974 1.5288950356918125 1.2554686353374669 0.3146868823829197 0.2613762066892051 0.1665759675679584 0.0507931717892238 0.0002459179565343 0.0018029983207632 +Stimuli sensing channels 4 9 2.3866854911112423 0.0170010284910913 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.0380950107843236 0.1706778675257841 0.0532804729840314 0.0133642522995781 0.0359117122080593 +Keratan sulfate keratin metabolism 4 5 2.3818847191669743 0.0172242885824096 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.000325764016582 0.0030581061915538 1.879762551529629e-05 4.060119731401367e-05 0.0010238181908857 +Mhc class ii antigen presentation 12 51 2.357306282440742 0.0184080569568465 14.065533980582524 53.91990291262136 0.0378305751056327 0.7050016235886306 7.205585512568872 4.251886159447844 0.7481875393236335 0.3070805603530936 0.0478917766550272 0.086158736226278 0.074977025310764 0.4432149385971948 0.0235992313294809 +Antigen processing cross presentation 13 55 2.35239066747606 0.018653172498583 13.364077669902912 51.03883495145631 0.6606344305939695 0.5456453275819227 6.483621701094183 2.525298521609755 1.0422529083240153 0.3659829171921698 0.1298049423458981 0.0546342218360011 0.0009276159222364 2.378163424288293e-06 6.91621639068202e-07 +Transport of small molecules 30 164 2.3513238439554427 0.0187067448673183 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 0.0034461099981992 0.0365561690816371 0.0011289483032464 2.517558416262504e-09 6.52382448698121e-06 +Interferon gamma signaling 5 13 2.3454415724709774 0.0190045569693633 3.4174757281553396 12.29126213592233 0.3504356398232429 0.5841793314671695 2.235087678151022 1.9577134867833192 0.8232177003646645 0.3100303898066223 1.0 1.0 0.0891217330395956 0.0354428499477605 0.0365963272398627 +Amyloid fiber formation 2 8 2.340180607009948 0.0192744165520166 2.233009708737864 6.37378640776699 -0.2774936642640803 0.43935586458948 1.249884526667495 1.3460089271800024 1.1189280269465711 0.3074138199875801 0.0044373898287515 0.1828652209005429 0.0074499229745329 0.0778634639331788 0.3228304985102302 +Rac2 gtpase cycle 7 40 2.3047116219718022 0.0211827295639952 8.905339805825243 34.74757281553398 0.8419178475366841 0.4471774138928159 4.131135699306596 3.707034631516275 0.9898490308362274 0.3561406142763811 0.4855704125934285 0.3295231102555642 0.1885261979805918 0.0007811205562282 0.0018139393434046 +Metabolism of carbohydrates 9 99 2.300871331155072 0.0213989050202432 24.106796116504853 96.5728155339806 -0.5221362188572046 0.5396051441609171 9.448031203305042 5.564453656914835 0.9880396829037232 0.3520896380798738 0.0012201653666371 0.0753845271099522 0.0007831431684808 0.0103261806002204 0.1825527330389258 +Integrin cell surface interactions 4 6 2.2872435816394905 0.0221816095154911 1.633495145631068 4.203883495145631 0.3179111363730327 0.4479127776597527 1.2499104501809644 0.9864049002328192 1.1220147725505705 0.3186356661300093 1.0 1.0 0.3060304729743218 0.0121856638082503 0.0324377486516598 +Amino acid transport across the plasma membrane 3 6 2.248387144587056 0.0245515141990217 1.6019417475728157 3.9466019417475726 0.6798215426479346 0.3497589750262466 1.2195001827124836 1.03907310581091 1.144086667263588 0.2965730694092905 1.0 1.0 1.0 0.0006430769062578 0.0079931710216612 +Laminin interactions 3 5 2.206258766339496 0.0273658866934589 1.1820388349514563 2.4514563106796117 -0.1747267989791531 0.4408051094089246 1.0535965765247446 1.2809556564230908 1.3052071677595742 0.3169431262072641 1.0 1.0 0.2030300441679912 0.0021324559374895 0.0236194052560011 +Signaling by erbb4 6 9 2.179127474602482 0.0293221997546853 2.453883495145631 7.257281553398058 0.4395977843708076 0.5106764734442939 1.5549199917041956 1.4851433811168728 0.8250198774172108 0.2950845076560141 0.2552924739487913 1.0 0.299132167535026 0.5900138775011101 0.0015247609081843 +Transferrin endocytosis and recycling 2 11 2.1761510695700097 0.029543966274371 3.186893203883495 10.822815533980584 0.6564894823668704 0.3913498590234048 1.8751111444734605 0.7728172110534567 1.0012961103567426 0.2928480452979678 0.0092050279194046 0.0847528009868792 0.0131546828557762 0.0089509329804495 0.0544656750173612 +Transport of inorganic cations anions and amino acids oligopeptides 3 12 2.1736740451764502 0.0297296232144195 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 1.0 1.0 1.0 0.0219504556074559 0.1653068273939545 +Signaling by notch4 19 43 2.1643775539163768 0.0304353850607468 12.74271844660194 42.689320388349515 0.5846962923720355 0.527528574888472 7.095179574371064 1.5202779907622044 1.22282479858509 0.3678962187540617 0.4414139941253555 1.0 0.5045129832066302 0.0294581500767194 0.0005937804181134 +Degradation of the extracellular matrix 5 12 2.163321947149354 0.0305164262035924 2.9854368932038833 8.45631067961165 -0.2764356066249684 0.4712903139856545 1.609975442554694 2.058733228327538 1.0124241638389404 0.2958639735684837 0.3680688343567227 1.0 0.4250358756773005 0.0474607851235824 0.0539791573859534 +Rhoj gtpase cycle 4 22 2.131862941021633 0.0330181155409519 6.264563106796117 21.990291262135923 -0.0841193333663617 0.6459480100408814 3.4416645545740954 3.7005513775234418 0.7389839366629946 0.2849144110201534 0.3628540514200035 0.237457799625543 0.4193097117028734 0.0107491623339001 0.0501645149458417 +Signal transduction by l1 4 12 2.11605678779245 0.0343399780763291 4.070388349514563 9.233009708737864 -0.3392645130539325 0.5305438109374768 2.313404762845765 1.6307356341981385 0.8207346553674568 0.2915088813020959 1.0 1.0 0.179062604831997 0.0012358112224234 0.0022722304352638 +Rhoq gtpase cycle 3 21 2.1087664400928205 0.0349647467259741 6.293689320388349 21.5873786407767 -0.1566130496377216 0.6616175057460224 3.609407742690307 3.506531481590953 0.7151985080066273 0.2896582153910753 0.3834615031303653 0.2523879312119707 0.4418810858922499 0.0556276904991455 0.1591907444431843 +Rnd1 gtpase cycle 3 17 2.0954612977846523 0.0361300054071218 3.9854368932038833 14.514563106796116 0.208877848589142 0.4518727246968532 2.1999076665085657 2.249548294118384 1.053267386868326 0.2884669841419 0.034496077063378 0.0133509861907553 0.0483495219963649 0.0110758722051871 0.0291816562890673 +Rhoa gtpase cycle 9 52 2.077491079431503 0.0377562577247654 11.383495145631068 46.157766990291265 0.7285935948010234 0.4866370775942555 5.135874153241841 5.803151375541917 0.959659542192298 0.3649179877597411 0.2979395130958837 0.4847391385004878 0.1443148752822858 0.001620105919091 0.0624651091924945 +Innate immune system 51 302 2.0751638942112542 0.0379713476579528 58.13106796116505 283.2621359223301 0.0553962685980947 0.7001179978548713 23.17655548398375 21.516966060472942 1.144037613250001 0.3669222261646001 1.512661992867024e-12 1.0723280730116973e-06 1.0239563319625248e-13 3.3987462780114946e-11 1.4011664831718122e-14 +Nuclear signaling by erbb4 4 5 2.059190611319733 0.0394759822226249 1.4053398058252426 3.907766990291262 0.3269683783863283 0.47748107812511 0.9991601478426048 0.8511772909670066 0.977051579872254 0.2957436340532913 0.1369226886862704 1.0 0.1626892876910785 0.3594428044513148 0.0013613651941044 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 5 13 2.0573445041145 0.0396530992923989 2.342233009708738 10.851941747572816 0.4093935303592591 0.5118730029355861 2.0859825428338192 2.5513980779067897 0.8583599781783465 0.2979240057989124 0.2910660683117588 0.1868885334554594 0.339526513295544 0.2737930251240831 0.0153479918417224 +Rac1 gtpase cycle 9 52 2.042123760849095 0.0411392564937014 9.54368932038835 42.69417475728155 0.2253898329174695 0.7210992809311206 5.10525466787569 6.274363391568892 0.623641978517273 0.2923111346436422 0.7139939392500794 0.528966667701962 0.441114647154086 0.0121753661989153 0.0675516921198531 +Glycogen metabolism 0 10 2.0253018629998447 0.0428363773515934 3.424757281553398 9.71359223300971 -0.0094610401248948 0.5726993883286675 2.26661474821283 1.434833540880879 0.8643148422001711 0.3023813170106142 0.1509425000049774 1.0 0.179062604831997 0.3904027877902372 0.2546657991273667 +O linked glycosylation 2 5 2.025138329406163 0.0428531620702208 1.766990291262136 4.330097087378641 0.8603336668848929 0.3169450005244383 1.1529100664253755 1.1773621125091884 1.0771631098821022 0.279831511700265 1.0 1.0 1.0 0.2102212619820596 0.2421884168027767 +Tnf signaling 5 12 2.024845969164062 0.0428831831202656 2.483009708737864 7.453883495145631 -0.1605863100031888 0.5145933999381181 1.812095999809916 2.782628056181418 0.9651354531750088 0.3033674958721901 0.2733967462722031 1.0 0.3196260593385788 0.2464598217650195 0.010788368915323 +Rhob gtpase cycle 6 27 2.0175880748395465 0.0436341798686246 6.548543689320389 22.475728155339805 -0.1484967621114408 0.5912272578357135 3.4430276831201954 4.42706736346575 0.8901000359800968 0.3110947621026433 0.4321434788255112 0.288471198078913 0.1468141932972727 0.0014147813856964 0.0184969351752434 +Non integrin membrane ecm interactions 4 11 2.017463697922657 0.0436471457306542 2.3810679611650487 5.682038834951456 -0.0725412144856926 0.5776386594360561 1.652573992657068 1.8534585143755615 0.8819938971562727 0.3098953498776026 1.0 1.0 0.3060304729743218 0.0121856638082503 0.0324377486516598 +Rhog gtpase cycle 7 41 2.005095769944612 0.0449528096223754 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 0.4414139941253555 0.295480255529908 0.1536294983436044 0.0003185447421997 0.0005937804181134 +Diseases of metabolism 8 48 2.004845314724707 0.0449795864094733 10.91747572815534 43.34708737864078 -1.309770160040866 0.249752463847892 4.21831253208471 4.914651787893876 1.4623549850590434 0.3091348346884224 9.080678455116852e-05 0.0004322926390732 4.140049582117231e-05 0.0047598111499749 0.0259933892636634 +Death receptor signalling 7 28 1.985438209873045 0.0470957383636623 5.645631067961165 23.54126213592233 -0.1102863609457894 0.6465088441574995 3.539054689729852 5.442171393384637 0.8141573628490125 0.3087559956450991 0.2556169370591458 1.0 0.3296925469859509 0.5649574510114895 0.2306589812452646 +Dap12 interactions 3 6 1.982554195494673 0.0474172480535286 1.7087378640776698 5.080097087378641 0.3818159854359121 0.5292922195385862 1.2038051963263134 1.0775250274350003 0.8665701791995095 0.3082952402815833 1.0 1.0 0.1871299927573601 0.0138257504316944 0.0172333771485565 +Antigen processing ubiquitination proteasome degradation 32 91 1.9749672916120729 0.0482718599693174 25.228155339805824 89.88592233009709 0.3040503636743611 0.5349081840989588 12.844717984151089 7.994482069951932 1.4235342488403817 0.383588489924638 0.8736769220325334 0.7118520401336006 0.9174859436133374 0.1587494062285357 0.0201146124962544 +Keratinization 2 8 1.966075944699169 0.0492898386410456 2.8470873786407767 5.691747572815534 -0.6850619911507018 0.3520169434460188 1.399866936164618 1.016671637173928 1.2355195198288238 0.313798966027817 0.0160900301160464 0.1114073342812727 0.0228441699597423 0.0199432580741765 0.1093101132411038 +Formation of the cornified envelope 2 8 1.966075944699169 0.0492898386410456 2.8470873786407767 5.691747572815534 -0.6850619911507018 0.3520169434460188 1.399866936164618 1.016671637173928 1.2355195198288238 0.313798966027817 0.0160900301160464 0.1114073342812727 0.0228441699597423 0.0199432580741765 0.1093101132411038 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..aaa0aaf1e6594db09a3765c670e715573a3c3d86 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 1404, + "title": "Average number of proteins per term", + "value": 19.97150997150997 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..383ab956865da799d5fc611fbfba0fc0720a4fc5 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4e16761e82777cbbda045804484add38ff5d0c5e --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,601 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Trans golgi network vesicle budding 0.810582809320939 3.5840433597241805 0.0003383158852539 0.3781621243418644 0.1899986043457336 39 Q99523,O43493,P15586,P02792,O00115,P05067,P11717,P02786,O75976 9 +Neutrophil degranulation 0.6946655687907072 3.5306612560188824 0.0004145222512059 0.4412817163918333 0.1899986043457336 178 Q9NV96,P15586,O00584,O00560,P61916,P06280,P84095,Q9BTY2,P11717,P07602,P04066,P42785,Q93050,P13473,P10619,P10253,P48960,O00754,P16278,P17900,P53634,Q92820,O15260,Q9NQX7,Q13510,Q92542,P11279,P02792,P07686,P04439,P06756,P01889,P09429,P04080,P27105,Q08722,P10321 37 +Response to elevated platelet cytosolic ca2 0.7626449452872562 3.25940449190504 0.0011164636442684 0.7916197295494328 0.1899986043457336 38 Q6YHK3,O43852,O60245,Q06481,Q9UEU0,Q08380,P13473,P05067,P07602 9 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.8739264324399318 3.148662019193787 0.0016401977309543 0.9002140848500865 0.1899986043457336 20 P19022,O43852,Q06481,O43493,P07942,Q08431,Q9BTY2,P05067,Q02818 9 +Golgi associated vesicle biogenesis 0.7780483576971116 3.1314229542211773 0.0017396142462942 0.9132344219085496 0.1899986043457336 32 Q99523,O43493,P11717,P02786,O75976 5 +Glycosphingolipid metabolism 0.9159721414626446 3.06993478668552 0.0021410551524847 0.9506720334067896 0.1899986043457336 15 Q13510,P06280,P10619,P07686,P16278,P17900,P07602,P06865 8 +Cargo recognition for clathrin mediated endocytosis 0.7433110106238391 3.0312313896402614 0.0024355852032391 0.9674094436884456 0.1899986043457336 35 Q14108,O43493,P01130,P20645,P11717,P02786 6 +Sphingolipid metabolism 0.7890465749568384 3.0273753555045544 0.0024668742708808 0.9688135169620132 0.1899986043457336 27 Q13510,P06280,P10619,P07686,P16278,P17900,P07602,P06865 8 +Glycosaminoglycan metabolism 0.9045210093015522 2.88980107222406 0.0038548567761607 0.9955846910244353 0.1899986043457336 13 P15586,P54802,O43505,P07686,P16278,P06865 6 +Extracellular matrix organization 0.6947587947157178 2.884954542772914 0.003914701823485 0.995941848044356 0.1899986043457336 39 P05556,P13591,P78536,Q92542,P07942,Q9Y624,Q14118,P11047,P35613,P05067,Q32P28,Q08722,P06756 13 +Clathrin mediated endocytosis 0.6258311992752068 2.7959566262045583 0.0051746344596375 0.9993135994601072 0.1899986043457336 58 Q14108,O43493,P01130,P20645,P11717,P02786 6 +Plasma lipoprotein clearance 0.8638393696099159 2.7947245840627652 0.0051943947201975 0.9993324773360344 0.1899986043457336 14 P01130,P61916,P38571,O15118 4 +Lysosome vesicle biogenesis 0.8547113920895731 2.754667429722185 0.005875182105657 0.9997447028703772 0.1943612173444609 14 P15586,O00115,P05067 3 +Plasma lipoprotein assembly remodeling and clearance 0.8088370349926478 2.746837322749267 0.006017297243021 0.9997911314974464 0.1943612173444609 18 P01130,P61916,P38571,O15118 4 +Gpcr ligand binding 0.9263941983193946 2.7231380481602216 0.0064665030668529 0.9998892740208568 0.1943612173444609 10 P42892,P07602,P05067,P22466 4 +Binding and uptake of ligands by scavenger receptors 0.9249461342474946 2.614953275489756 0.0089239662505873 0.999996578695859 0.2237365824254396 9 P02792,Q07954,Q5KU26 3 +Ldl clearance 0.8545334083272298 2.60423196700466 0.0092080412075887 0.9999977123351388 0.2268085939553447 12 P01130,P61916,O15118 3 +Diseases of carbohydrate metabolism 0.9338982314017744 2.5437852356023236 0.0109658484291876 0.9999998109187124 0.2296463199871466 8 P15586,P54802,P10253 3 +Cell surface interactions at the vascular wall 0.7485865424686036 2.5378303967037423 0.0111542025772639 0.9999998552844248 0.2296463199871466 20 P05556,Q9Y624,Q92896,P35613,O00459,P78310,P08195,P06756 8 +Ion channel transport 0.706816783645472 2.5339989987198517 0.0112769053950787 0.9999998784237744 0.2296463199871466 26 Q93050,P27105,Q15904,P51790,Q96PU5,Q9C0H2 6 +Iron uptake and transport 0.7449360529657951 2.4898188647663013 0.012780821408991 0.9999999856559564 0.2296463199871466 19 P02786,Q15904,P02792 3 +Rac3 gtpase cycle 0.6365361991210281 2.474316467320806 0.0133491389638304 0.999999993609234 0.2296463199871466 38 Q14126,P05556,Q9NSV4,Q14739,O00459,P29317,P02786,P43121 8 +Peptide ligand binding receptors 0.9398460231468312 2.464439790957655 0.0137227616877715 0.999999996244994 0.2296463199871466 7 P42892,P07602,P05067 3 +Class a 1 rhodopsin like receptors 0.9398460231468312 2.464439790957655 0.0137227616877715 0.999999996244994 0.2296463199871466 7 P42892,P07602,P05067 3 +Slc mediated transmembrane transport 0.6743943221773268 2.437488890240626 0.014789668676483 0.999999999178408 0.240821553863106 28 Q6PCB8,P30825,Q96QD8,O00400,Q9H2J7,P08195,Q15043,P11166 8 +G alpha i signalling events 0.7026155093952205 2.4314817482628075 0.0150372059176748 0.9999999994226548 0.240821553863106 24 P07602,P05067 2 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.9306753942279028 2.4301088387026444 0.0150942893365391 0.9999999994677736 0.240821553863106 7 P05556,P01889,Q5KU26,P04439,P78310,P10321 6 +Netrin 1 signaling 0.8480430464032925 2.406892201373077 0.0160889181265027 0.9999999998711702 0.2455308809740195 10 O94813,Q92859 2 +Ecm proteoglycans 0.9211544183278718 2.3943153543802143 0.0166514251672809 0.9999999999422808 0.2513828057512086 7 P05556,P13591,P07942,P11047,P05067,P06756 6 +Stimuli sensing channels 0.8670685514060353 2.3866854911112423 0.0170010284910913 0.9999999999649652 0.2526231075324406 9 Q96PU5,P51790,P27105,Q9C0H2 4 +Keratan sulfate keratin metabolism 0.9687778768956254 2.3818847191669743 0.0172242885824096 0.9999999999745318 0.2526231075324406 5 P15586,P07686,P16278,P06865 4 +Mhc class ii antigen presentation 0.577785294769419 2.357306282440742 0.0184080569568465 0.9999999999953108 0.2560397667555927 51 P04350,Q9BUF5,O43237,Q14203,P47756,P10619,Q9H0H5,Q13885,Q99538,P53634,P09496,Q13409 12 +Antigen processing cross presentation 0.5717674609300034 2.35239066747606 0.018653172498583 0.9999999999966976 0.2560397667555927 55 P01889,Q9UIQ6,P09429,P28070,P28074,P10321,P28072,Q9Y6K9,Q92530,P49721,P04439,Q9UBG0,P06756 13 +Transport of small molecules 0.5583023364825639 2.3513238439554427 0.0187067448673183 0.9999999999969412 0.2560397667555927 164 Q6PCB8,P01130,P30825,P61916,O00400,P02786,Q9C0H2,P08183,Q13438,Q93050,Q92530,P49721,Q15043,P33527,O15118,P28070,P02792,Q15904,P51790,P28072,Q10713,P38571,Q96PU5,Q8WTV0,P10644,P11166,P27105,Q96QD8,Q9H2J7,P08195 30 +Interferon gamma signaling 0.779600693172143 2.3454415724709774 0.0190045569693633 0.9999999999980026 0.2560397667555927 13 P01889,P13591,Q12899,P04439,P10321 5 +Amyloid fiber formation 0.8811023246112707 2.340180607009948 0.0192744165520166 0.9999999999986426 0.2560397667555927 8 P05067,Q92542 2 +Rac2 gtpase cycle 0.6006106561234664 2.3047116219718022 0.0211827295639952 0.9999999999999118 0.2679489759651412 40 Q14126,P05556,Q9NSV4,Q14739,P29317,P02786,P43121 7 +Metabolism of carbohydrates 0.5078757677957336 2.3008713311550717 0.0213989050202432 0.9999999999999354 0.2679489759651412 99 P15586,P54802,O43505,P10253,P07686,O00754,P16278,Q9Y2E5,P06865 9 +Integrin cell surface interactions 0.9110878392806904 2.2872435816394905 0.0221816095154911 0.999999999999979 0.2711946275176071 6 P05556,P35613,Q9Y624,P06756 4 +Amino acid transport across the plasma membrane 0.9007479298331288 2.248387144587056 0.0245515141990217 0.9999999999999992 0.2744493783185691 6 Q9H2J7,P08195,Q96QD8 3 +Laminin interactions 0.921156212349078 2.206258766339496 0.0273658866934589 1.0 0.2929872418644595 5 P05556,P07942,P06756 3 +Keratan sulfate degradation 0.9759215219976214 2.1978026881336152 0.0279631698075766 1.0 0.2929872418644595 4 P15586,P16278,P06865 3 +Signaling by erbb4 0.8158312261501386 2.179127474602482 0.0293221997546853 1.0 0.2981456499503214 9 P78536,Q92542,P62993,P61201,P49768,P16949 6 +Transferrin endocytosis and recycling 0.770238247816365 2.1761510695700097 0.029543966274371 1.0 0.2981456499503214 11 P02786,Q15904 2 +Transport of inorganic cations anions and amino acids oligopeptides 0.7560069440378161 2.1736740451764502 0.0297296232144195 1.0 0.2981456499503214 12 Q9H2J7,P08195,Q96QD8 3 +Signaling by notch4 0.5645491411167696 2.1643775539163768 0.0304353850607468 1.0 0.2996158209079982 43 P28074,Q13200,O75832,Q15008,Q92530,Q04721,P60900,P49768,P49721,P63104,Q92542,Q99436,P28070,O43242,P25786,P28072,P55036,P51665,P25788 19 +Degradation of the extracellular matrix 0.753701051389959 2.163321947149354 0.0305164262035924 1.0 0.2996158209079982 12 P78536,Q92542,P07942,P11047,P35613 5 +Endosomal vacuolar pathway 0.9640309155766932 2.15466065273199 0.0311883989851171 1.0 0.3040868901048923 4 P04439,Q9UIQ6,P01889 3 +Rhoj gtpase cycle 0.6600770234329184 2.131862941021633 0.0330181155409519 1.0 0.3132259068884897 22 P02786,Q86VI3,P27105,Q9NSV4 4 +Scavenging by class a receptors 0.9562745935649052 2.1264228652855337 0.0334680655632348 1.0 0.3153635171193408 4 Q5KU26 1 +Signal transduction by l1 0.7432083791978842 2.11605678779245 0.0343399780763291 1.0 0.3192935709878552 12 P05556,P13591,P06756,O14786 4 +Rhoq gtpase cycle 0.6611337387303597 2.1087664400928205 0.0349647467259741 1.0 0.3210539720987284 21 P02786,P27105,Q9NSV4 3 +Rnd1 gtpase cycle 0.6864391282972092 2.0954612977846523 0.0361300054071218 1.0 0.3210539720987284 17 P02786,O75976,P29317 3 +Rhoa gtpase cycle 0.539858573629164 2.077491079431503 0.0377562577247654 1.0 0.3290850130355913 52 O60245,Q9NSV4,Q14739,Q8NBN3,Q86VI3,P27105,Q15904,P02786,P43121 9 +Innate immune system 0.5685920416500495 2.0751638942112542 0.0379713476579528 1.0 0.3290850130355913 302 Q9NV96,P15586,O00584,P28074,P61916,O00560,Q13526,P06280,P84095,P67870,Q9BTY2,P05067,P11717,Q99538,P07602,Q13685,P04066,P42785,Q8IV08,Q93050,P13473,P10619,P10253,P48960,Q92530,O00754,P16278,P49721,P17900,P53634,Q92820,O15260,Q9NQX7,Q13510,Q92542,P11279,P28070,P02792,P28072,P07686,O00459,P04439,P06756,P01889,P09429,P04080,P27105,Q86VP1,Q08722,Q9UQB8,P10321 51 +Nuclear signaling by erbb4 0.881950639310126 2.059190611319733 0.0394759822226249 1.0 0.3326408237616184 5 P49768,P16949,P78536,Q92542 4 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7168280205124923 2.0573445041145 0.0396530992923989 1.0 0.3326408237616184 13 Q13685,P61088,Q9Y6K9,P05067,P08238 5 +Hyaluronan metabolism 0.936712177393364 2.054873523903674 0.0398912223353131 1.0 0.3326408237616184 4 P06865 1 +Hyaluronan uptake and degradation 0.936712177393364 2.054873523903674 0.0398912223353131 1.0 0.3326408237616184 4 P06865 1 +Rac1 gtpase cycle 0.5353083865902012 2.042123760849095 0.0411392564937014 1.0 0.3326408237616184 52 P05556,Q9NSV4,Q14739,Q86VI3,O00459,P29317,P02786,P43121,Q9Y2I1 9 +O linked glycosylation 0.8729545704198425 2.025138329406163 0.0428531620702208 1.0 0.3326408237616184 5 Q10472,O43505 2 +Tnf signaling 0.7231209133764016 2.024845969164062 0.0428831831202656 1.0 0.3326408237616184 12 P78536,Q6GQQ9,Q86VP1,Q9Y6K9,Q8TCT8 5 +Sialic acid metabolism 0.9270100861023276 2.0192165854352293 0.0434647132215593 1.0 0.3330466989447744 4 P10619 1 +Rhob gtpase cycle 0.6105962887120963 2.0175880748395465 0.0436341798686246 1.0 0.3330466989447744 27 O60245,Q9NSV4,P27105,Q86VI3,P02786,P43121 6 +Non integrin membrane ecm interactions 0.7342828212929049 2.0174636979226572 0.0436471457306542 1.0 0.3330466989447744 11 P05556,P07942,P06756,P11047 4 +Rhog gtpase cycle 0.5528530752961393 2.005095769944612 0.0449528096223754 1.0 0.3377076968925162 41 Q14126,P05556,Q14739,P84095,P29317,P02786,P43121 7 +Diseases of metabolism 0.5343916563455173 2.004845314724707 0.0449795864094733 1.0 0.3377076968925162 48 P15586,P54802,P10619,P10253,P07686,P16278,Q9NPF0,P06865 8 +Death receptor signalling 0.5988613151323037 1.985438209873045 0.0470957383636623 1.0 0.3426964111106947 28 P78536,Q92542,Q6GQQ9,Q86VP1,Q9Y6K9,P49768,Q8TCT8 7 +Dap12 interactions 0.8311774658637017 1.982554195494673 0.0474172480535286 1.0 0.3426964111106947 6 P10321,P01889,O00459 3 +Heparan sulfate heparin hs gag metabolism 0.9159174781620248 1.9783136314593792 0.0478933362675053 1.0 0.3430726740794771 4 P54802,P16278 2 +Antigen processing ubiquitination proteasome degradation 0.4675037892298526 1.9749672916120729 0.0482718599693174 1.0 0.3440288903397043 91 Q9UIQ6,P28074,Q13200,Q12834,O75832,P46934,Q9Y4B6,Q16763,Q15008,P61088,Q13617,P49459,Q92530,P60900,P49721,P28070,Q13309,Q99436,O43242,P25786,Q05086,P28072,Q96PU5,Q9UNE7,Q96J02,P55036,P51665,Q9C0C9,Q8TBC4,Q6UWE0,P25788,P55786 32 +Keratinization 0.7873351091743113 1.966075944699169 0.0492898386410456 1.0 0.3477534344323019 8 Q14574,Q02487 2 +Formation of the cornified envelope 0.7873351091743113 1.966075944699169 0.0492898386410456 1.0 0.3477534344323019 8 Q14574,Q02487 2 +Role of abl in robo slit signaling 0.902503867816454 1.928664320751594 0.0537725483384525 1.0 0.3561163106942802 4 O94813 1 +Signaling by notch3 0.814873041190759 1.9191813693880493 0.0549613844913028 1.0 0.3585834961065766 6 P67809,Q92542 2 +Platelet activation signaling and aggregation 0.5087655291095403 1.9179942567984525 0.0551117393836826 1.0 0.3585834961065766 61 Q6YHK3,Q13685,Q92520,O60245,Q06481,Q9UEU0,O43852,Q08380,P13473,P84095,P05067,P07602 12 +Myogenesis 0.8129184798879994 1.9115581169590763 0.0559328957602138 1.0 0.3585834961065766 6 P19022,Q92859 2 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5769639359863928 1.9017616314656467 0.0572023244463002 1.0 0.3634030023647309 31 O60884,Q15185,P54652,P47756,Q13409,P04350,Q96FJ2,O43237,Q9Y6G9,P31689,P08238,Q13561,Q02790,P52907,P61163,Q9BUF5,P07900,Q13885,Q9UJW0,Q14203 20 +Hemostasis 0.493570587670481 1.8997294272199097 0.0574686364670253 1.0 0.3634502954941605 134 O60245,Q06481,P84095,P05067,P07602,P78310,P05556,Q13685,P42785,Q9UEU0,Q08380,P13473,Q6YHK3,Q92520,Q92896,O00459,P10644,P06756,O43852,Q9Y624,P35613,P08195 22 +Signaling by vegf 0.5790200906750737 1.8961114714302456 0.0579453060233976 1.0 0.3648215679679385 30 Q13685,P04792,P63000,Q96JJ3,O43865,P07900,P46108,Q9Y6W5,O00459,Q13177,Q9UQB8,O14786,P06756 13 +Rnd2 gtpase cycle 0.624666364754131 1.884279978940362 0.0595271141006337 1.0 0.366814287522069 20 P02786,Q9Y2I1,P29317 3 +Retrograde transport at the trans golgi network 0.6198479859578891 1.8820487573039817 0.0598293958992548 1.0 0.366814287522069 21 P11717,O43493 2 +Sema3a pak dependent axon repulsion 0.764285714285715 1.871731919226249 0.0612437012460547 1.0 0.3722344439370598 8 P63000,Q9UIW2,P07900,Q16512,Q13177,P08238,O14786 7 +Eph ephrin mediated repulsion of cells 0.6634309405768181 1.8656137401251456 0.0620954258676544 1.0 0.3751925841889331 14 P49768,Q15375,Q92542,P29317 4 +Intra golgi and retrograde golgi to er traffic 0.4649232897114667 1.864404893719381 0.0622648661795024 1.0 0.3751925841889331 101 Q14746,O43493,P47756,P20645,P11717,Q10472,Q8TBA6,Q13409,P04350,Q15643,O43237,Q9H0H5,P54920,O00461,O15260,Q9BUF5,Q8TD16,O60476,O43731,Q9H2M9,Q9Y678,O60664,P43034,P35606,Q13885,Q14203 26 +Class i mhc mediated antigen processing presentation 0.4772232261336008 1.8598908085520045 0.0629009760223318 1.0 0.3757998737674631 117 Q9UIQ6,P28074,Q12834,Q9Y6K9,Q9Y4B6,Q9UBG0,P61088,P49459,Q92530,P60900,P49721,P28070,Q13309,Q99436,P28072,Q96PU5,P04439,Q96J02,P06756,P01889,Q9C0C9,P09429,Q8TBC4,Q6UWE0,P55786,P10321 26 +Regulation of tnfr1 signaling 0.7354370101599833 1.8431744903333096 0.0653035381556565 1.0 0.3832970201336629 9 Q6GQQ9,Q86VP1,Q8TCT8 3 +Hs gag degradation 0.9842543077837196 1.8401454229308456 0.0657468901068951 1.0 0.3832970201336629 2 P54802 1 +Chondroitin sulfate dermatan sulfate metabolism 0.8774196336824185 1.8352922665346063 0.0664623963180046 1.0 0.3832970201336629 4 P06865 1 +Diseases associated with glycosaminoglycan metabolism 0.8774196336824185 1.8352922665346063 0.0664623963180046 1.0 0.3832970201336629 4 P06865 1 +Inactivation of cdc42 and rac1 0.876588469582815 1.8321872265699752 0.0669235312677323 1.0 0.3832970201336629 4 O94813 1 +Interleukin 1 signaling 0.5127293969329739 1.831556795426886 0.0670174786717041 1.0 0.3832970201336629 47 P28074,Q13200,O75832,Q9Y6K9,P05067,Q15008,P61088,Q92530,P60900,P49721,Q02750,Q99436,P28070,O43242,P25786,P28072,P55036,P51665,P09429,P25788 20 +Visual phototransduction 0.7531317735949254 1.825757967856604 0.0678867271800285 1.0 0.3843415853979492 8 P01130 1 +Interferon alpha beta signaling 0.711410824863923 1.824832828306473 0.0680262602559476 1.0 0.3843415853979492 10 P04439,P01889,P10321 3 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.774529626610912 1.8239267668486907 0.068163144418867 1.0 0.3843415853979492 7 Q9Y6K9,P05067,P09429 3 +Diseases associated with glycosylation precursor biosynthesis 0.7726065414383387 1.8162172385368824 0.0693370547436798 1.0 0.3893968994405057 7 P10619 1 +Role of phospholipids in phagocytosis 0.8703083599962488 1.80870405564772 0.070496992585638 1.0 0.3920823259017301 4 Q8IV08 1 +Chaperone mediated autophagy 0.7707146361703091 1.8086274261158768 0.0705089046929305 1.0 0.3920823259017301 7 P08238,O60664,P13473 3 +Regulation of runx3 expression and activity 0.5419140192806082 1.8050963003918423 0.0710596139075097 1.0 0.3920823259017301 37 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,P42771,Q92530,P60900,P49721,P55036 16 +Cs ds degradation 0.9753416518122408 1.804957587878303 0.0710813190900347 1.0 0.3920823259017301 2 P06865 1 +Mtor signalling 0.6442234672811231 1.804126147368067 0.0712115335505279 1.0 0.3920823259017301 15 P23588,Q8N122,Q96B36,P06730,Q9Y376,Q15382,P62942 7 +Scf skp2 mediated degradation of p27 p21 0.5231400964271351 1.7888798196502695 0.0736341724595104 1.0 0.4034484727676335 41 P51665,Q15008,Q99436,P28074,Q13200,Q13309,P28070,O43242,O75832,P25786,P25788,P28072,Q92530,P60900,P49721,P55036 16 +Met promotes cell motility 0.7434059999821059 1.7855060808593972 0.0741792658883584 1.0 0.4034484727676335 8 P05556,P07942,P62993,P11047 4 +Regulated proteolysis of p75ntr 0.8637100231076629 1.783989793382446 0.0744253236800691 1.0 0.4034484727676335 4 P78536,Q92542 2 +Advanced glycosylation endproduct receptor signaling 0.7205898202344699 1.7798176102270415 0.0751058146416738 1.0 0.4055713990650389 9 P05067 1 +Activation of rac1 0.7772230776364204 1.7713933859702469 0.076495307688702 1.0 0.4083627832507135 6 O94813 1 +Activated notch1 transmits signal to the nucleus 0.8593935790725286 1.7678002865144002 0.0770942970155659 1.0 0.4100014886736914 4 P49768,P78536,Q92542 3 +Transport of bile salts and organic acids metal ions and amine compounds 0.7559659959602494 1.749283694499395 0.0802419930551312 1.0 0.4206581127051985 7 Q9H2J7,Q6PCB8,Q15043 3 +Mucopolysaccharidoses 0.9845468053491828 1.7449810098477008 0.0809881746139669 1.0 0.4206581127051985 3 P15586,P54802 2 +Adaptive immune system 0.511158604000877 1.7448132183487393 0.081017387146437 1.0 0.4206581127051985 191 Q9UIQ6,P28074,Q12834,P62993,Q5KU26,Q9Y6K9,Q9Y4B6,Q99538,P62942,P78310,Q9UBG0,Q13409,P05556,P04350,P61088,P10619,Q9H0H5,P49459,Q92530,P60900,P49721,P53634,P28070,Q13309,Q99436,Q9BUF5,P28072,O00459,Q13177,Q96PU5,P04439,Q96J02,P06756,P01889,Q9C0C9,P09429,Q8TBC4,Q6UWE0,Q14203,Q92692,P25788,P55786,P10321,P09496 44 +Regulation of commissural axon pathfinding by slit and robo 0.9554367201426032 1.726214695627618 0.0843087951952337 1.0 0.4246749801278145 2 O94813 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.621925708015395 1.7255992774887765 0.0844195294414873 1.0 0.4246749801278145 16 P04439,P01889 2 +Rnd3 gtpase cycle 0.5988441844649293 1.720744336121852 0.0852972272452678 1.0 0.4246749801278145 19 O75976,Q9Y2I1,P29317 3 +Cilium assembly 0.4820185371941871 1.7150840586246645 0.086329816591669 1.0 0.4258520919607399 63 Q15691,P23258,O60645,Q8TAG9,Q13409,P62258,P04350,Q15643,Q13561,Q9BUF5,P07900,Q10713,P41208,Q9Y366,Q9UPT5,O43924,O94927,Q7Z4H7,P43034,P06493,P36405,P07437,Q13885,Q15154,A6NIH7,Q14203 26 +Sensory perception 0.560482773321638 1.7106806796876874 0.0871400761753014 1.0 0.4277785557696614 27 P01130 1 +Mapk family signaling cascades 0.4391005762172469 1.7074453128709688 0.0877393142142357 1.0 0.4286565137985402 89 P13591,P28074,Q13200,O75832,P62993,Q15008,P04792,Q96P70,Q92530,P60900,P49721,Q12959,P63000,Q02750,P28070,Q99436,O43242,Q9Y4G8,P25786,P28072,O00459,Q13177,Q99956,P55036,P51665,P28482,O43924,P20618,P25788,P06493,Q16181,Q14168,O60725 33 +Post chaperonin tubulin folding pathway 0.7035002479369477 1.7064219790691348 0.0879295412920082 1.0 0.4286565137985402 9 O75347,P04350,Q9BUF5,Q99426 4 +Cross presentation of soluble exogenous antigens endosomes 0.5237664719430537 1.7040497671775323 0.0883717900345351 1.0 0.4293217758079145 38 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,Q9UBG0,P55036 16 +E2f enabled inhibition of pre replication complex formation 0.7577407867761804 1.6941813296334067 0.0902308315083104 1.0 0.4354091885167171 6 Q9Y619,Q9UJA3,Q13416 3 +Semaphorin interactions 0.5863960483259795 1.694106397648082 0.0902450668506871 1.0 0.4354091885167171 21 P05556,P35579,P63000,Q9UIW2,P07900,Q16512,Q13177,P60660,P08238,O14786,P23528 11 +Autophagy 0.4911568842067274 1.6916620172945704 0.0907104344258613 1.0 0.4361556504585936 52 Q9UQN3,Q9Y3E7,P54619,P67870,Q8NCE2,Q13409,P04350,P61088,P60520,O43237,P13473,P08238,Q9NS69,Q9BUF5,Q8N4H5,Q8N122,O60664,Q13885,Q15382 19 +Signaling by notch1 pest domain mutants in cancer 0.7200995633082562 1.6884512206172968 0.0913246451870333 1.0 0.4363840705071019 8 P78536,Q92542 2 +Pi3k akt signaling in cancer 0.6805429390099731 1.6881649451629617 0.0913795703198632 1.0 0.4363840705071019 10 Q96B36,O00459,P84095 3 +Synthesis of substrates in n glycan biosythesis 0.6370211747021409 1.6771029757064926 0.0935223470217301 1.0 0.440727037526187 13 P10619 1 +E2f mediated regulation of dna replication 0.6364326213053763 1.6742444195648565 0.0940825728813516 1.0 0.440727037526187 13 P49642,Q9UJA3,Q13416,P09884,P06400,P06493,Q9Y619,Q14181,P30154,P30153 10 +L1cam interactions 0.4932330317400784 1.6697523471005509 0.0949683720984841 1.0 0.441326249450218 45 P13591,P15311,O00560,P67870,A0MZ66,P05556,P04350,Q96P70,Q13740,Q12959,P63000,Q02750,Q9BUF5,P11047,P06756,P07942,Q13885,P09496,O14786 19 +Cdc42 gtpase cycle 0.5292528098031075 1.668364023781735 0.0952434854582735 1.0 0.441326249450218 35 Q9NSV4,Q14739,P27105,Q86VI3,O00459,P02786 6 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.5879771286866493 1.660810519908062 0.0967515076858287 1.0 0.4453741534127985 19 P09429,Q13526,Q86VP1,Q9Y6K9,P05067,P08238 6 +Uptake and actions of bacterial toxins 0.7121918009518075 1.6553390031354258 0.0978557514664273 1.0 0.4454388862042279 8 Q02750,P07900,Q7L0J3,P08238,Q16881 5 +Ras processing 0.8292969165823413 1.6544708072857834 0.0980318900165153 1.0 0.4454388862042279 4 O43924 1 +Signaling by notch1 0.6729881614388797 1.6544573280437482 0.0980346266646057 1.0 0.4454388862042279 10 P49768,P78536,Q92542 3 +Traf6 mediated nf kb activation 0.7112917346121836 1.6515645762092448 0.0986233463577574 1.0 0.4466683170525533 8 P05067,P09429 2 +Interleukin 1 family signaling 0.4877691719013224 1.645898863497879 0.0997845829902337 1.0 0.4504744518272932 49 P28074,Q13200,O75832,Q9Y6K9,P05067,Q15008,P61088,Q92530,P60900,P49721,Q02750,Q99436,P28070,O43242,P25786,P28072,P55036,P51665,P09429,P25788 20 +Negative regulation of notch4 signaling 0.5109299549794549 1.6390705604478022 0.1011985653874745 1.0 0.4553935442436353 39 P51665,Q15008,P63104,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Metabolism of fat soluble vitamins 0.7244278457444214 1.6213988516872533 0.104932126887054 1.0 0.4706859621387342 7 P01130 1 +Vesicle mediated transport 0.52380960638261 1.6140023593592034 0.1065269145277596 1.0 0.4721458072081609 271 Q9UQN3,Q9Y3E7,Q14746,P54619,Q9UIQ6,O43493,P01130,P15586,P47756,Q5KU26,P20645,P62993,P05067,P11717,P61201,Q9BXI6,Q8TAG9,P02786,Q8TBA6,Q8TC07,Q10472,O75976,Q9H9Q2,Q13409,Q14108,Q99523,P04350,Q15643,Q07954,P60520,Q0IIM8,Q86X10,Q9H0H5,P53634,P54920,O00461,O15260,Q9UKS6,Q9BUF5,P02792,O00115,Q9H3P7,Q8TD16,Q8WTV0,O43731,O60476,P42566,P11233,Q9H2M9,Q9Y678,Q9NVZ3,O60664,P43034,P35606,Q9UNF0,Q13885,Q92734,Q14203,P09496 59 +Syndecan interactions 0.7223443268769181 1.612906528926244 0.1067648165331909 1.0 0.4721458072081609 7 P06756 1 +Copi independent golgi to er retrograde traffic 0.5366641823199476 1.608484883696079 0.1077290242514847 1.0 0.4721458072081609 29 Q9H2M9,P04350,Q8TD16,Q9BUF5,O43237,P43034,P47756,Q13885,Q10472,Q14203,Q13409 11 +Cdc6 association with the orc origin complex 0.8162357553048947 1.6050737418458558 0.1084775771708517 1.0 0.4721458072081609 4 Q9Y619,Q13416 2 +O linked glycosylation of mucins 0.945412131189128 1.604424843368764 0.1086204385528746 1.0 0.4721458072081609 3 O43505 1 +Diseases of glycosylation 0.5571148541520426 1.5982482905263438 0.109987730437411 1.0 0.4745815126633343 24 P10619,P16278,P07686,P06865 4 +Crmps in sema3a signaling 0.7328380148577971 1.5948366882202998 0.1107487604403283 1.0 0.4745815126633343 6 O14786 1 +Rhoc gtpase cycle 0.5196437791422385 1.580956156553489 0.1138880627964791 1.0 0.4784932745949246 34 Q9NSV4,Q14739,P27105,P02786,P43121 5 +Met activates ptk2 signaling 0.9387815750371472 1.5805521913297622 0.1139804645145856 1.0 0.4784932745949246 3 P07942,P05556 2 +Transcriptional regulation by runx3 0.4950542530575558 1.5798472076206052 0.1141418616210931 1.0 0.4784932745949246 41 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,P42771,Q92530,P60900,P49721,P25440,P55036 17 +Activation of ampk downstream of nmdars 0.7287057572157362 1.5782879978960662 0.114499461940555 1.0 0.4784932745949246 6 P04350,Q9BUF5,Q13885 3 +Elastic fibre formation 0.9379971571896916 1.577727177421241 0.1146282999067223 1.0 0.4784932745949246 3 P06756 1 +Molecules associated with elastic fibres 0.9379971571896916 1.577727177421241 0.1146282999067223 1.0 0.4784932745949246 3 P06756 1 +Vitamin d calciferol metabolism 0.9377270930815124 1.576754528453827 0.1148520181898073 1.0 0.4784932745949246 3 Q99538 1 +Mtorc1 mediated signalling 0.625339077845009 1.5679367404740805 0.1168958963510977 1.0 0.483577878302621 12 P23588,Q8N122,Q96B36,P06730,P62942 5 +Constitutive signaling by aberrant pi3k in cancer 0.7239101098370286 1.5590617189266365 0.1189817730182767 1.0 0.4847232419606647 6 O00459,P84095 2 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.752082691861056 1.5579100525713736 0.1192545718860094 1.0 0.4847232419606647 5 O00459 1 +Translation of replicase and assembly of the replication transcription complex 0.7520656358672297 1.5578430748426202 0.1192704521822598 1.0 0.4847232419606647 5 Q9H444,Q9Y3E7,Q9UQN3 3 +Cholesterol biosynthesis 0.5813520894484114 1.5475273351417331 0.1217361382319524 1.0 0.4905210389689173 17 Q16850,Q14739,Q9UBM7,Q15392 4 +Signaling by egfr 0.5981520683725445 1.5407109805657857 0.123387143159884 1.0 0.4907522634461112 14 Q13685,P78536,Q9UBC2,Q06124,P62993,O14964,P42566 7 +Nrif signals cell death from the nucleus 0.9076054664289984 1.536455632359372 0.1244266713811099 1.0 0.4920987228706433 2 Q92542 1 +Synthesis of pc 0.7453081174839626 1.531290443571049 0.1256976263427458 1.0 0.4957288409697054 5 P35790 1 +Chl1 interactions 0.923779599019267 1.5265008159533098 0.1268851873964838 1.0 0.49761676844878 3 O14786 1 +Raf independent mapk1 3 activation 0.6983040761678068 1.5145726344879415 0.1298806666896794 1.0 0.5079455599785793 7 P28482,Q02750,P06493,Q06124,P36507,Q99956 6 +Insulin receptor recycling 0.6362928623033198 1.489440149827434 0.1363715025867313 1.0 0.5258009223393774 10 Q15904 1 +The role of gtse1 in g2 m progression after g2 checkpoint 0.4677623009017562 1.4846010835284813 0.1376495282807315 1.0 0.5263051013701939 49 Q15691,P28074,Q13200,O75832,Q15008,P04350,Q92530,P60900,P49721,P08238,Q99436,P28070,Q9BUF5,O43242,P07900,P25786,P28072,P55036,P51665,P25788,P06493,Q13885 22 +Dap12 signaling 0.7841921732972922 1.4834725079796705 0.1379489154588542 1.0 0.5263051013701939 4 P62993,O00459 2 +Signaling by insulin receptor 0.5731794634475664 1.4709050007337137 0.1413168100934627 1.0 0.5322726738855753 16 Q15904,O00459,Q93050 3 +Noncanonical activation of notch3 0.9078751857355128 1.469166128092524 0.1417877350663854 1.0 0.5322726738855753 3 P67809,Q92542 2 +Notch3 activation and transmission of signal to the nucleus 0.9078751857355128 1.469166128092524 0.1417877350663854 1.0 0.5322726738855753 3 P67809,Q92542 2 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.7766738850097382 1.4548804937534716 0.1457023488713722 1.0 0.5412069552000093 4 P46108,Q96JJ3 2 +Rhoh gtpase cycle 0.5411416470597434 1.454854433522328 0.1457095648615409 1.0 0.5412069552000093 22 P02786,P27105 2 +Erks are inactivated 0.6972040452111833 1.4516305150152022 0.1466043692291827 1.0 0.5416645642046646 6 P28482,Q14738,P51452,P30154,P27361 5 +Negative regulation of the pi3k akt network 0.5884139346520513 1.4387180025944564 0.1502304365804341 1.0 0.5492800337472121 13 P28482,P63000,Q14738,Q06124,P84095,P62993,O00459,P30154,P27361 9 +Insulin receptor signalling cascade 0.6935280607283205 1.4368014949130237 0.1507744055238793 1.0 0.5498370528714976 6 P62993,P28482,O00459,Q06124 4 +Signalling to ras 0.8814616755793225 1.4327235886962637 0.1519368455650367 1.0 0.5509159919250893 2 P11233 1 +Ephrin signaling 0.7199674476355347 1.4314724915916062 0.1522948453718184 1.0 0.5509159919250893 5 Q13177,O00560,P63000 3 +Alk mutants bind tkis 0.6778009684826143 1.4302689958245611 0.1526398296715525 1.0 0.5509159919250893 7 P10644 1 +Uptake and function of diphtheria toxin 0.7691623596008825 1.4263002528525108 0.1537816916662602 1.0 0.5536140899985368 4 P08238,P07900 2 +Cobalamin cbl vitamin b12 transport and metabolism 0.7172194220586695 1.4206295333028016 0.1554244880238315 1.0 0.5557695028896192 5 Q9NPF0 1 +Gap junction assembly 0.7672698006565444 1.4190977283729485 0.1558705261323199 1.0 0.5557695028896192 4 P04350,Q9BUF5 2 +Transport of connexons to the plasma membrane 0.7672698006565444 1.4190977283729485 0.1558705261323199 1.0 0.5557695028896192 4 P04350,Q9BUF5 2 +Aggrephagy 0.5672634209120662 1.4103523633817443 0.1584356639459363 1.0 0.5589036989449614 15 P04350,P61088,Q13409,Q96FJ2,Q9BUF5,O43237,P07900,Q9Y6G9,Q13885,P08670 10 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5660749401913933 1.4041739454734057 0.1602670583581731 1.0 0.5629876359180168 15 Q99471,P04350,P50991,P61758,Q9UHV9,Q9BUF5,P50990,Q13885,Q9BVA1,P17987,Q99832 11 +Basigin interactions 0.6517951656039699 1.3998839673518584 0.1615480678385052 1.0 0.5629876359180168 8 P05556,P08195 2 +Other semaphorin interactions 0.8731431966726113 1.3997651434285825 0.1615836589886679 1.0 0.5629876359180168 2 P05556 1 +Assembly and cell surface presentation of nmda receptors 0.6162462813812737 1.3985139166981833 0.1619587965282334 1.0 0.5629876359180168 10 Q14168,P04350,Q9BUF5,Q13885 4 +Signaling by notch 0.4477146083008232 1.3974753009466627 0.1622706889494343 1.0 0.5629876359180168 61 P28074,Q13200,O75832,Q15008,P78536,Q92530,Q04721,P60900,P49768,P49721,P63104,Q92542,Q99436,P28070,O43242,P25786,P67809,P28072,Q96J02,P55036,P51665,P25788 22 +Cyclin a cdk2 associated events at s phase entry 0.458760080149251 1.3936326214478592 0.1634285723809521 1.0 0.5629876359180168 44 P51665,Q15008,Q99436,P28074,Q13200,Q13309,P28070,O43242,O75832,P25786,P25788,P28072,Q92530,P60900,P49721,P55036 16 +Irs mediated signalling 0.759732074286544 1.3904073318888772 0.1644052213150904 1.0 0.5629876359180168 4 O00459 1 +Hur elavl1 binds and stabilizes mrna 0.6814435292651008 1.3879969365292166 0.165137977961683 1.0 0.5641209758107129 6 Q01105 1 +Membrane trafficking 0.5003393331990529 1.3710550338260987 0.170357800886054 1.0 0.5777351508309657 263 Q9UQN3,Q9Y3E7,Q14746,P54619,Q9UIQ6,O43493,P01130,P15586,P47756,P20645,P62993,P61201,P05067,P11717,Q9BXI6,Q8TAG9,P02786,Q8TBA6,Q8TC07,Q10472,O75976,Q9H9Q2,Q13409,Q14108,Q99523,P04350,Q15643,P60520,Q0IIM8,Q86X10,Q9H0H5,P53634,P54920,O00461,O15260,Q9UKS6,Q9BUF5,P02792,O00115,Q9H3P7,Q8TD16,P42566,O43731,O60476,P11233,Q9H2M9,Q9Y678,Q9NVZ3,O60664,P43034,P35606,Q9UNF0,Q13885,Q92734,Q14203,P09496 56 +Cdt1 association with the cdc6 orc origin complex 0.4671927010799546 1.368257263058605 0.171231563015197 1.0 0.5789425652037232 41 P51665,Q15008,Q9UJA3,Q99436,P28074,Q13200,P28070,Q13416,O43242,O75832,P25786,P25788,P28072,Q9Y619,Q92530,P60900,P49721,P55036 18 +Late endosomal microautophagy 0.592754640634043 1.367276873081543 0.1715385378381402 1.0 0.5789425652037232 11 Q9UQN3,Q9Y3E7,Q9H444,Q99816,O60664,Q8WUX9 6 +Cell junction organization 0.5335820251065112 1.3559027076760355 0.1751301259043061 1.0 0.5849477965060624 19 P05556,P19022,Q9Y624 3 +Hsf1 dependent transactivation 0.555663962799186 1.349952027302271 0.1770313714148645 1.0 0.5849477965060624 15 Q8N122,P04792,Q15185,P07900,P08238,Q96B36 6 +Energy dependent regulation of mtor by lkb1 ampk 0.6400595394191688 1.3498393145688148 0.1770675309936442 1.0 0.5849477965060624 8 Q8N122,Q9Y376,Q15382 3 +Cd28 dependent vav1 pathway 0.6985282307335506 1.3468228219920906 0.1780373026710069 1.0 0.5867708285213468 5 P62993,Q13177,P63000 3 +Displacement of dna glycosylase by apex1 0.8733860235098947 1.3449057133671465 0.1786556849641751 1.0 0.5870615586771543 3 P13051 1 +Diseases associated with o glycosylation of proteins 0.87072808320951 1.3353431345368345 0.1817640671299558 1.0 0.5921038288873736 3 O43505,Q14118 2 +Signaling by notch2 0.8707280832095101 1.3353431345368345 0.1817640671299558 1.0 0.5921038288873736 3 P49768,Q92542 2 +Notch2 activation and transmission of signal to the nucleus 0.8707280832095101 1.3353431345368345 0.1817640671299558 1.0 0.5921038288873736 3 P49768,Q92542 2 +Cell cell junction organization 0.616403902416745 1.325870085691003 0.1848827331606557 1.0 0.5996421352404784 9 P19022,Q9Y624 2 +Nod1 2 signaling pathway 0.6512567270576245 1.3206954444955494 0.1866029336535581 1.0 0.6031129421484474 7 Q9Y6K9,Q13685,P61088 3 +Hedgehog off state 0.4450030513412645 1.3169009155211828 0.187871839583579 1.0 0.6031129421484474 53 P28074,Q13200,O75832,Q15008,P04350,Q92530,P60900,P49721,Q99436,P28070,Q9BUF5,O43242,P25786,Q2M1P5,P28072,Q9Y366,Q96J02,P55036,P10644,P51665,P25788,Q13885 22 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6501379215655447 1.3160697923852722 0.1881506187044301 1.0 0.6031129421484474 7 P49642,P06400,Q14181,P30154,P30153 5 +Regulation of hmox1 expression and activity 0.4478994120872642 1.3089181290592178 0.1905620849220508 1.0 0.6066874540375496 45 P51665,Q15008,Q99436,P28074,Q13200,Q13309,Q8TCT9,P67870,O75832,P28070,O43242,P25786,P28072,Q92530,P25788,P60900,P49721,P55036 18 +Orc1 removal from chromatin 0.4445819141216887 1.3032776330225193 0.1924799943574313 1.0 0.6088860876335658 51 P28074,Q13200,Q13416,O75832,Q15008,Q92530,P60900,P49721,Q9UJA3,Q99436,Q13309,P28070,O43242,P25786,P28072,P55036,P51665,P25788,Q9Y619 19 +Regulation of pten stability and activity 0.4585838466468231 1.3020997130009004 0.1928823012721596 1.0 0.6088860876335658 41 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P67870,O75832,P25786,P25788,P28072,Q92530,P46934,P60900,P49721,Q9UNE7,P55036 18 +Leishmania infection 0.4466810713111964 1.2967088558012274 0.1947313811301465 1.0 0.6116395058316012 44 P78536,P63000,P63096,Q96JJ3,Q9UBI6,O43865,Q9UQB8,P62993,P46108,Q9Y6W5,P05067,P08238,O15143,P10644 14 +Cargo trafficking to the periciliary membrane 0.5127085045732619 1.2865181764256473 0.1982622794400161 1.0 0.6149850046410327 22 A6NIH7,O43924 2 +Eph ephrin signaling 0.4794769602622226 1.2852264560540525 0.1987131611928172 1.0 0.6149850046410327 33 Q92542,O00560,Q15375,P29317,P49768,O15143,P09496 7 +Fatty acyl coa biosynthesis 0.5382143147115135 1.2851403307322555 0.1987432503215831 1.0 0.6149850046410327 16 Q9UMR5 1 +Intraflagellar transport 0.5644900611831283 1.2747763861043986 0.202388401077654 1.0 0.6204220853996205 12 P04350,Q15643,Q96FJ2,Q9BUF5,Q13885,Q92973,Q9BVA1,Q9Y366 8 +Epha mediated growth cone collapse 0.5875685083513977 1.2677593691003264 0.2048838960684031 1.0 0.6215754575443588 10 Q15375 1 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.6031287924673181 1.2672007084572678 0.2050835325341058 1.0 0.6215754575443588 9 Q16763,P49459,P45974 3 +Ire1alpha activates chaperones 0.4947172614346753 1.2660204109087558 0.2055057748564981 1.0 0.6215754575443588 26 O14773 1 +Tcr signaling 0.4410489912511995 1.265536362791042 0.2056791218813756 1.0 0.6215754575443588 49 P28074,Q13200,O75832,Q16512,P63208,Q9Y6K9,Q15008,P61088,Q92530,P60900,P49721,Q99436,P28070,O43242,P25786,P28072,O00459,Q13177,Q04206,P55036,P51665,P62333,P20618,P25788 24 +Recruitment of mitotic centrosome proteins and complexes 0.4764930876496699 1.264464572497557 0.2060633288104563 1.0 0.6215754575443588 33 Q15691,P04350,O94927,Q7Z4H7,P43034,P07900,P06493,P07437,P23258,Q15154,P41208,Q96CW5,Q13561,Q14203,Q13409 15 +Cell cell communication 0.4822692374503997 1.2625551307019536 0.2067491016190994 1.0 0.6215754575443588 30 P05556,P19022,Q9Y624,Q92692,O00459 5 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8448513851844998 1.2424460724161048 0.214072025796665 1.0 0.6340867599546788 3 Q9Y624 1 +Cytosolic sulfonation of small molecules 0.7193444079834012 1.2367935882363754 0.2161637230644899 1.0 0.6363947432306062 4 Q9NX62 1 +Notch4 activation and transmission of signal to the nucleus 0.8412978263779634 1.2297252057918793 0.2188000246593324 1.0 0.6409662974805502 3 Q92542 1 +Rhou gtpase cycle 0.509460434813196 1.2185419655191774 0.223018087501944 1.0 0.6476119604539796 19 P62993,O00459,P29317,O14964,Q13177,Q03001 6 +Regulation of runx2 expression and activity 0.4402867800459553 1.214901371210098 0.2244037107590848 1.0 0.6482773866373562 43 P51665,Q15008,Q99436,P28074,Q13200,Q13309,P28070,O43242,O75832,P25786,P25788,P28072,Q92530,P60900,P49721,Q9UNE7,P55036 17 +Mapk6 mapk4 signaling 0.4339220174106532 1.2101055814214674 0.2262383817400906 1.0 0.6494226113014121 50 P28074,Q13200,O75832,Q15008,P04792,Q92530,P60900,P49721,P63000,Q99436,P28070,O43242,P25786,P28072,Q13177,P55036,P51665,P20618,P25788,P06493,Q16181 21 +Ncam signaling for neurite out growth 0.6244973979866296 1.2099989713756272 0.2262792875922628 1.0 0.6494226113014121 7 P13591 1 +Sealing of the nuclear envelope ne by escrt iii 0.5589922684351711 1.207858196840869 0.2271018115000287 1.0 0.6494226113014121 11 Q9H444,Q9UQN3,Q9Y3E7,P04350,Q9BUF5,Q13885,Q8WUX9 7 +Mastl facilitates mitotic progression 0.6633281905024602 1.207829392216352 0.2271128932685138 1.0 0.6494226113014121 5 P06493,P30154,Q96GX5 3 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5840510120375246 1.1827755324102878 0.2368981199966533 1.0 0.66660012335073 9 P07942,Q16850,P11047 3 +Attenuation phase 0.5534777875824646 1.1817657434062392 0.2372986639131831 1.0 0.66660012335073 11 P08238,P04792,P07900,Q15185 4 +Intra golgi traffic 0.5078578271924178 1.1773821086854204 0.2390430276395272 1.0 0.66660012335073 18 Q14746,Q15643,Q8TBA6,O60476,P54920,O00461 6 +Nucleotide salvage 0.6163335003724164 1.176232098957956 0.2395021408698285 1.0 0.66660012335073 7 P00492,Q9BZX2,P07741 3 +Translocation of slc2a4 glut4 to the plasma membrane 0.4568888700454679 1.176171197624871 0.2395264715607157 1.0 0.66660012335073 36 Q9UPT5,P35579,P62258,P04350,Q9UIQ6,P54619,P63104,P63000,Q86X10,Q9BUF5,O60343,P27348,Q13885,O60645,Q8TAG9,P11233,Q12846 17 +Toll like receptor cascades 0.4723295617950432 1.175304287687258 0.2398729997372124 1.0 0.66660012335073 28 Q99538,P05067,P09429 3 +Fcgamma receptor fcgr dependent phagocytosis 0.4563347681586652 1.1721455125665572 0.2411386399183162 1.0 0.66660012335073 36 P28482,P63000,Q96JJ3,Q8IV08,O43865,P07900,Q9UQB8,P62993,Q16512,P46108,Q9Y6W5,O00459,P08238,O15143,P23528 15 +Formation of tubulin folding intermediates by cct tric 0.5427504309868416 1.1691409965149433 0.2423468288398425 1.0 0.66660012335073 12 P04350,P50991,Q9BUF5,P50990,Q13885,Q9BVA1,P17987,Q99832 8 +Anchoring of the basal body to the plasma membrane 0.4646879748142205 1.1679980716710834 0.2428075427188851 1.0 0.66660012335073 32 Q15691,P04350,O94927,Q7Z4H7,P43034,P07900,P06493,P07437,Q15154,P41208,Q13561,Q14203,Q13409 13 +Fc epsilon receptor fceri signaling 0.4259105867459337 1.1653765247609544 0.2438666153957844 1.0 0.66660012335073 55 P28074,Q13200,O75832,P62993,Q9Y6K9,Q15008,P61088,Q92530,P60900,P49721,P63000,Q99436,P28070,O43865,O43242,P25786,P28072,O00459,Q13177,P55036,P51665,P28482,P20618,P25788 24 +Signaling by gpcr 0.4296578468161911 1.1606229378970907 0.2457952730675545 1.0 0.66660012335073 45 P42892,P07602,P05067,P22466 4 +Negative regulators of ddx58 ifih1 signaling 0.5956048162558923 1.159774788722973 0.2461405112247923 1.0 0.66660012335073 8 Q86VP1,Q13526 2 +Negative feedback regulation of mapk pathway 0.6976813317479136 1.154724185881798 0.2482033919796933 1.0 0.6675815370488327 4 Q02750,P28482,P36507 3 +Mapk3 erk1 activation 0.6976813317479134 1.1547241858817958 0.2482033919796942 1.0 0.6675815370488327 4 Q02750,Q06124,P06493 3 +Nuclear receptor transcription pathway 0.808674985145575 1.146385404448215 0.2516357191681058 1.0 0.6741264056032376 2 Q15648 1 +Signalling to erks 0.5607941894021737 1.1453186536624655 0.2520771815824072 1.0 0.6741264056032376 10 P28482,Q02750,P46108,P62993,P36507,P27361,P11233 7 +Ret signaling 0.606699238632637 1.1364134766463108 0.2557835582107697 1.0 0.6793793816793937 7 O00459 1 +Metabolism of polyamines 0.4460688991210831 1.135593993861761 0.2561265236915342 1.0 0.6793793816793937 38 P51665,Q15008,Q99436,P28074,Q13200,P28070,P19623,O43242,O75832,P25786,P25788,P28072,Q92530,P60900,P49721,P55036 16 +Carboxyterminal post translational modifications of tubulin 0.6440201069841758 1.131818026875346 0.2577109472617853 1.0 0.6793793816793937 5 P04350,Q9BUF5 2 +Downregulation of erbb4 signaling 0.8039215686274528 1.1279311435609534 0.2593489999716056 1.0 0.6793793816793937 2 Q96J02 1 +Runx3 regulates p14 arf 0.8027332144979222 1.1233243586009756 0.2612997621843822 1.0 0.6793793816793937 2 P42771 1 +Hedgehog ligand biogenesis 0.4286476830943947 1.1217260753998135 0.2619789261480159 1.0 0.6797650921980029 43 P51665,Q15008,P78536,Q13438,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 17 +Auf1 hnrnp d0 binds and destabilizes mrna 0.431527964206999 1.1175455146337838 0.2637611502277881 1.0 0.6797650921980029 42 P51665,Q15008,P04792,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Signaling by met 0.4870936443779051 1.1173321060995025 0.2638523527206196 1.0 0.6797650921980029 21 P05556,Q96P70,P07942,P62993,P11047,P46108,O14964,P42566 8 +Metabolism of steroids 0.428095574373611 1.1172933258132611 0.2638689282392532 1.0 0.6797650921980029 43 P04062,Q14739,Q9UBM7,Q16850,Q15392,O95772,Q99538 7 +Abc family proteins mediated transport 0.4193453346219297 1.114162391445432 0.2652095263962479 1.0 0.6802095568215656 56 P28074,Q13200,O75832,Q15008,P08183,Q13438,Q92530,P60900,P49721,P33527,Q99436,P28070,O43242,P25786,P28072,P55036,P05198,P51665,P20042,P25788,Q9NP58 21 +Purine salvage 0.6391226596931691 1.1125884622082167 0.2658852179714486 1.0 0.6802095568215656 5 P00492,P07741 2 +Aryl hydrocarbon receptor signalling 0.8083209509658253 1.112294642197288 0.2660114867649903 1.0 0.6802095568215656 3 O00170,P08238 2 +Extra nuclear estrogen signaling 0.5306775820461701 1.1104278736533415 0.2668146925267094 1.0 0.6802095568215656 12 P04792,P63096,Q9UBI6,P07900,O00459 5 +Transcriptional regulation by runx2 0.4195661147093066 1.1012133865766596 0.27080379687064 1.0 0.688360835465341 53 P28074,P17931,Q13200,O75832,Q15008,Q92530,Q07812,P49721,P60900,Q99436,Q13309,P28070,O43242,P25786,P28072,Q9UNE7,P55036,P51665,P28482,P25788,P06493 21 +Recruitment of numa to mitotic centrosomes 0.4458294453944477 1.0956579076127937 0.2732285097547486 1.0 0.6912534212177434 36 Q15691,P04350,O94927,Q7Z4H7,Q9BUF5,P43034,P07900,P06493,P07437,Q13885,Q15154,P41208,Q13561,Q14203,Q13409 15 +Transport to the golgi and subsequent modification 0.3889195105610509 1.09205900951847 0.2748071648885259 1.0 0.6939375170926088 81 Q14746,P47756,O15027,O60763,Q13409,P04350,P04066,P49755,Q96FJ2,O43237,Q12907,Q13561,P53634,P54920,P56962,Q08379,P52907,Q9BUF5,O60476,O43731,Q9H9E3,Q9Y678,P48444,P35606,Q13885,Q92734,Q14203 27 +Diseases of immune system 0.6798653983245662 1.0875771876965703 0.2767818060290929 1.0 0.6976690406909273 4 P09429 1 +G1 s dna damage checkpoints 0.4305826987713221 1.0847780089814596 0.2780199876599174 1.0 0.6985993005687587 41 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,P42771,Q92530,P60900,P49721,P55036 16 +Gpvi mediated activation cascade 0.6040776848373004 1.0752161174802073 0.2822779810589135 1.0 0.7006459641921341 6 P84095 1 +Lipophagy 0.6764687931833048 1.0748226398673706 0.2824541422597919 1.0 0.7006459641921341 4 O60664 1 +Nef and signal transduction 0.789067142008321 1.0705585901632857 0.2843679513175206 1.0 0.7041492127862414 2 Q13177 1 +Stabilization of p53 0.431061717223665 1.0650035203313823 0.2868743367051223 1.0 0.7052866319122086 40 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,P42771,Q92530,P60900,P49721,P55036 16 +Signaling by ntrk3 trkc 0.6736565839989636 1.0642756272704066 0.2872038557271956 1.0 0.7052866319122086 4 P62993 1 +Recycling of eif2 gdp 0.5891363734533103 1.063977266505299 0.2873389981864553 1.0 0.7052866319122086 7 Q13144,P49770,P05198,Q9NR50 4 +Downstream signaling events of b cell receptor bcr 0.4178659430834707 1.062742259462832 0.2878988508309907 1.0 0.7054275507272444 44 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q9Y6K9,Q92530,P60900,P49721,P62942,P55036 17 +Asymmetric localization of pcp proteins 0.4351280520044375 1.0536640252620582 0.2920367649127471 1.0 0.7118396144748211 38 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 15 +Signaling by ntrk2 trkb 0.6228818446844355 1.049022768926449 0.294167639210976 1.0 0.715201495905481 5 P62993,P63000 2 +Degradation of axin 0.4359068814752482 1.0405611430332742 0.2980792730409896 1.0 0.7189967435648401 37 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 15 +Signaling by mapk mutants 0.7810457516339896 1.0397873910214672 0.2984386884402532 1.0 0.7189967435648401 2 Q99956 1 +Cellular response to hypoxia 0.4276730430843524 1.038869889647 0.298865251716184 1.0 0.7189967435648401 40 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,Q13617,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Signaling by the b cell receptor bcr 0.4142221486295339 1.037310659108448 0.2995910997552837 1.0 0.7189967435648401 47 P28074,Q13200,O75832,P62993,Q9Y6K9,P62942,Q15008,Q92530,P60900,P49721,Q99436,P28070,O43865,O43242,P25786,P28072,P55036,P51665,P25788 19 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6196929198538755 1.0365848348423112 0.2999293839185131 1.0 0.7189967435648401 5 Q9UIW2,O14786 2 +Rho gtpases activate nadph oxidases 0.5943764428760542 1.0362316544457968 0.30009408242806 1.0 0.7189967435648401 6 P28482,Q13526,P63000 3 +Signaling by hedgehog 0.4049586367938487 1.0255081182490495 0.3051234968327008 1.0 0.7240427949467142 62 P28074,Q13200,O75832,Q15008,P04350,P78536,Q13438,Q92530,P60900,P49721,Q99436,P28070,Q9BUF5,O43242,P25786,Q2M1P5,P28072,Q96J02,Q9Y366,P55036,P10644,P51665,P25788,Q13885 24 +Activation of kainate receptors upon glutamate binding 0.7835929064482278 1.0252391399929597 0.3052503643856132 1.0 0.7240427949467142 3 Q12959 1 +G protein mediated events 0.5131194516337086 1.0251210698325048 0.3053060649651522 1.0 0.7240427949467142 12 P52292,O43865,P10644,P63096 4 +Degradation of dvl 0.4305424410212038 1.0192390216615472 0.308089505371228 1.0 0.7257678952033626 38 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 15 +Regulation of ras by gaps 0.4305424410212038 1.0192390216615472 0.308089505371228 1.0 0.7257678952033626 38 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 15 +Aurka activation by tpx2 0.4394358881470742 1.00460303110734 0.3150880371511668 1.0 0.7364901655509879 33 Q15691,P04350,O94927,Q7Z4H7,P43034,P07900,P06493,P07437,Q15154,P41208,Q13561,Q14203,Q13409 13 +Clec7a dectin 1 signaling 0.4096311084723392 1.0034008972366493 0.3156674713788727 1.0 0.7364901655509879 49 P28074,Q13200,O75832,Q9Y6K9,Q15008,P61088,Q92530,P60900,P49721,Q99436,P28070,O43865,O43242,P25786,P28072,P55036,P51665,Q8TBC4,P25788 19 +Long term potentiation 0.6099826008072019 0.9988161724703338 0.3178837501822489 1.0 0.7364901655509879 5 Q14168 1 +Ras activation upon ca2 influx through nmda receptor 0.6099826008072019 0.9988161724703338 0.3178837501822489 1.0 0.7364901655509879 5 Q14168 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.6099826008072019 0.9988161724703338 0.3178837501822489 1.0 0.7364901655509879 5 Q14168 1 +Unblocking of nmda receptors glutamate binding and activation 0.6099826008072019 0.9988161724703338 0.3178837501822489 1.0 0.7364901655509879 5 Q14168 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.5821489899957079 0.987282893506963 0.3235039744157131 1.0 0.7368825556946096 6 P62993,P42566 2 +Dscam interactions 0.7670825906120058 0.9866284704901844 0.3238248077706362 1.0 0.7368825556946096 2 P63000 1 +Constitutive signaling by egfrviii 0.6050338048077102 0.9796350442383706 0.3272662999622 1.0 0.7368825556946096 5 P62993,P07900 2 +Signaling by erbb2 ecd mutants 0.6050338048077102 0.9796350442383706 0.3272662999622 1.0 0.7368825556946096 5 P62993,P07900 2 +Signaling by egfr in cancer 0.6050338048077102 0.9796350442383706 0.3272662999622 1.0 0.7368825556946096 5 P62993,P07900 2 +Signaling by erbb2 in cancer 0.6050338048077102 0.9796350442383706 0.3272662999622 1.0 0.7368825556946096 5 P62993,P07900 2 +Constitutive signaling by ligand responsive egfr cancer variants 0.6050338048077102 0.9796350442383706 0.3272662999622 1.0 0.7368825556946096 5 P62993,P07900 2 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.4060140588743378 0.9783441269007616 0.327904152228623 1.0 0.7368825556946096 51 Q14240,O75821,P62851,P62847,P62249,P62266,Q13347,P62854,P08708,P08865,P60866,O00303,P46782,P23588,Q9Y262,P62273,Q04637,P06730,P55884,P05198,O15372,P20042,P25398,O75822,Q15056,P46783,P23396 27 +Pcp ce pathway 0.4064573514648296 0.9745517997162118 0.3297826326630586 1.0 0.7396402815637928 48 P51665,Q15008,P09496,P63000,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P07737,P25786,P28072,Q92530,P60900,P49721,P55036 18 +Cd163 mediating an anti inflammatory response 0.7620320855615026 0.9675410440797624 0.3332736334133639 1.0 0.7439281490472591 2 P78536 1 +Synaptic adhesion like molecules 0.5771129612465998 0.9671956793830654 0.3334462216847857 1.0 0.7439281490472591 6 P10586,O75955,Q12959 3 +Dna replication initiation 0.5497438918412835 0.9644271390442986 0.3348318213463919 1.0 0.74401195283858 8 P49642,Q14181,Q9NR33,Q9NRF9 4 +Tie2 signaling 0.7644669013728935 0.958719098449216 0.3377002745333368 1.0 0.746420935663643 3 O00459 1 +Dectin 1 mediated noncanonical nf kb signaling 0.4109873768314311 0.9544264445023805 0.3398678256786389 1.0 0.746420935663643 42 P51665,Q15008,Q8TBC4,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Degradation of gli1 by the proteasome 0.4104999064478954 0.9505433531905468 0.3418362362766565 1.0 0.746420935663643 42 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,Q96J02,P55036 16 +Switching of origins to a post replicative state 0.3969022158032637 0.9337592877582298 0.3504280746247423 1.0 0.7580909349354981 59 P28074,Q13200,Q13416,O75832,Q16763,Q15008,Q92530,P60900,P49721,Q9UJA3,Q99436,Q13309,P28070,O43242,P25786,P28072,P55036,P51665,P25788,Q9Y619 20 +Dag and ip3 signaling 0.5418842508100613 0.9312203211430996 0.351739608236421 1.0 0.7597575537906694 8 O43865,P10644 2 +Heme degradation 0.5901389400021491 0.9222256671980624 0.3564108774370567 1.0 0.7614318107459741 5 P33527 1 +Signaling by fgfr4 0.5518021114630275 0.9112776909647092 0.3621490778841445 1.0 0.762012907904084 7 P62993,P28482,P27361,Q06124 4 +Signaling by fgfr3 0.5518021114630275 0.9112776909647092 0.3621490778841445 1.0 0.762012907904084 7 P62993,P28482,P27361,Q06124 4 +Signaling by fgfr1 0.5518021114630275 0.9112776909647092 0.3621490778841445 1.0 0.762012907904084 7 P62993,P28482,P27361,Q06124 4 +Signal regulatory protein family interactions 0.7493827589811465 0.9068790132915706 0.3644707803758606 1.0 0.7648983193538242 3 Q08722 1 +Sumoylation of immune response proteins 0.7453951277480749 0.905262351210604 0.3653264167129173 1.0 0.7655496851715462 2 Q9Y6K9 1 +Rhobtb3 atpase cycle 0.6294954244534661 0.9006803080438053 0.3677583216615141 1.0 0.768162733715018 4 O60664 1 +P75 ntr receptor mediated signalling 0.4605386534891764 0.8891854175239736 0.3739034385882875 1.0 0.768162733715018 17 P78536,Q92542 2 +Negative regulation of fgfr3 signaling 0.557070761760574 0.887782543682583 0.3746577346107127 1.0 0.768162733715018 6 P62993,P28482,P27361,Q06124 4 +Negative regulation of fgfr4 signaling 0.557070761760574 0.887782543682583 0.3746577346107127 1.0 0.768162733715018 6 P62993,P28482,P27361,Q06124 4 +Negative regulation of fgfr2 signaling 0.557070761760574 0.887782543682583 0.3746577346107127 1.0 0.768162733715018 6 P62993,P28482,P27361,Q06124 4 +Negative regulation of fgfr1 signaling 0.557070761760574 0.887782543682583 0.3746577346107127 1.0 0.768162733715018 6 P62993,P28482,P27361,Q06124 4 +Spry regulation of fgf signaling 0.557070761760574 0.887782543682583 0.3746577346107127 1.0 0.768162733715018 6 P62993,P28482,P27361,Q06124 4 +Cell death signalling via nrage nrif and nade 0.5028171417553665 0.8815520791919946 0.3780190791583362 1.0 0.768162733715018 10 Q92542 1 +Proton coupled monocarboxylate transport 0.7402577273537994 0.8758275219005224 0.3811238057920039 1.0 0.768162733715018 3 Q6PCB8 1 +Generation of second messenger molecules 0.6192803674749453 0.8635419810133041 0.3878395480747914 1.0 0.768162733715018 4 Q13177 1 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3924722331741637 0.8607939360962059 0.3893515453744545 1.0 0.768162733715018 50 Q16763,P51665,Q15008,Q99436,P28074,Q13200,Q13309,P28070,Q12834,O75832,O43242,P25786,P28072,P25788,Q92530,P60900,P49721,P55036 18 +Egfr downregulation 0.5102808282909137 0.8583152978533947 0.3907183844425146 1.0 0.768162733715018 9 P62993,P42566,O14964 3 +Hedgehog on state 0.3959922480812881 0.858116815831777 0.3908279627873794 1.0 0.768162733715018 43 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,Q2M1P5,P28072,Q92530,P60900,P49721,Q96J02,P55036 17 +Neddylation 0.3774174989518302 0.8569574752951908 0.3914683866701982 1.0 0.768162733715018 72 P28074,Q13200,O75832,P61201,Q9H9Q2,Q92905,Q15008,Q13617,Q92530,P60900,P49721,Q99436,Q13309,Q7L5N1,P28070,O43242,Q9BW61,P25786,P28072,P55036,P51665,Q8TBC4,P20618,P25788,Q13564 25 +Signal amplification 0.5360650692497247 0.8477696570022109 0.3965662646414145 1.0 0.768162733715018 7 Q13685,P63096 2 +Pi 3k cascade fgfr1 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Activated ntrk2 signals through frs2 and frs3 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Pi 3k cascade fgfr4 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Signaling by flt3 itd and tkd mutants 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Frs mediated fgfr4 signaling 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Pi 3k cascade fgfr3 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Stat5 activation 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Frs mediated fgfr3 signaling 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Stat5 activation downstream of flt3 itd mutants 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Frs mediated fgfr2 signaling 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Met activates ptpn11 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Pi 3k cascade fgfr2 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Frs mediated fgfr1 signaling 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.768162733715018 2 P62993 1 +Other interleukin signaling 0.7310549777117392 0.8447740430890229 0.3982370097656 1.0 0.768162733715018 3 Q15833,Q12846 2 +Small interfering rna sirna biogenesis 0.6140483288516412 0.844649428849377 0.3983066026670463 1.0 0.768162733715018 4 Q15631,Q99598 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4937052606134171 0.8406290860125335 0.4005557589820496 1.0 0.771440721002466 10 Q9BU89,P63241 2 +Rhod gtpase cycle 0.4195718527107324 0.8369820326923878 0.4026026675347787 1.0 0.7727758157787357 30 Q07960,Q9NSV4,Q9UIW2,Q14739,Q9H0H5,O00459,P43121 7 +Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.7266785502079667 0.8364528139415052 0.4029002116453237 1.0 0.7727758157787357 2 Q06124 1 +Abc transporter disorders 0.3900774150790759 0.8347908136045726 0.4038354990651582 1.0 0.7733798191261608 45 P51665,Q15008,Q13438,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q9NP58,Q92530,P60900,P49721,P55036 17 +Constitutive signaling by overexpressed erbb2 0.610797831309651 0.8329593767991035 0.4048676403545073 1.0 0.7733798191261608 4 P62993,P07900 2 +Cell extracellular matrix interactions 0.5295272999135179 0.8215932301507327 0.4113084435520409 1.0 0.7810821985410892 7 P05556 1 +Metabolism of lipids 0.4247168929174327 0.8209381474261546 0.4116815006555598 1.0 0.7810821985410892 191 Q9UBM7,P06280,Q9UMR5,P50897,O95772,Q99538,P07602,P06865,Q8IV08,Q14739,Q8NCC3,P10619,O43772,P16278,P17900,P34913,P33527,Q13510,Q15126,Q10713,P07686,Q15392,P04062,P35790,Q16850 25 +Fceri mediated nf kb activation 0.3869522510370945 0.8089477623209771 0.418545194189746 1.0 0.7887751042179911 45 P51665,Q15008,P61088,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q9Y6K9,Q92530,P60900,P49721,P55036 17 +Condensation of prometaphase chromosomes 0.4970467037852144 0.8011714169577479 0.4230324160436431 1.0 0.7919955147981586 9 P67870,P06493 2 +Signaling by pdgf 0.5103385721133578 0.7994154585674588 0.4240495497777983 1.0 0.7919955147981586 8 P62993,O00459 2 +Downstream signal transduction 0.5103385721133578 0.7994154585674588 0.4240495497777983 1.0 0.7919955147981586 8 P62993,O00459 2 +Downstream signaling of activated fgfr4 0.717081364503197 0.7981786498791578 0.4247668252443115 1.0 0.7919955147981586 3 P62993 1 +Downstream signaling of activated fgfr2 0.717081364503197 0.7981786498791578 0.4247668252443115 1.0 0.7919955147981586 3 P62993 1 +Downstream signaling of activated fgfr1 0.717081364503197 0.7981786498791578 0.4247668252443115 1.0 0.7919955147981586 3 P62993 1 +Downstream signaling of activated fgfr3 0.717081364503197 0.7981786498791578 0.4247668252443115 1.0 0.7919955147981586 3 P62993 1 +Mitotic g1 phase and g1 s transition 0.3607342800464851 0.7871121011288846 0.4312162461002511 1.0 0.8008301713290378 80 P12004,P28074,Q13200,P04818,Q13416,O75832,P63208,P42771,P49642,Q15008,Q92530,P60900,P49721,P63151,Q9UJA3,P28070,Q13309,Q99436,O43242,P25786,P06400,P28072,Q9NR33,Q9NRF9,O75419,P55036,P51665,P62333,P20618,P25788,P06493,Q9Y619,P30154 33 +Met activates rap1 and rac1 0.5522960937321915 0.7792466145826613 0.4358344556850948 1.0 0.8037361017570881 5 P46108,P62993,P63000 3 +Unfolded protein response upr 0.3861796116385472 0.7786254403517242 0.4362003884379999 1.0 0.8037361017570881 43 O14773 1 +C type lectin receptors clrs 0.381704003938032 0.7785993747131011 0.4362157475348298 1.0 0.8037361017570881 54 P28074,Q13200,O75832,Q9Y6K9,Q15008,P61088,Q92530,P60900,P49721,Q99436,P28070,O43865,O43242,P25786,P28072,Q13177,P55036,P51665,Q8TBC4,P20618,P25788 21 +Interleukin receptor shc signaling 0.7105324304061515 0.7765932194075611 0.4373988032584146 1.0 0.8041574081282823 3 O00459 1 +Tnfr2 non canonical nf kb pathway 0.3885440010194945 0.7754282267532739 0.4380866612192453 1.0 0.8041574081282823 42 P51665,Q15008,Q8TBC4,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Mapk1 erk2 activation 0.7096582466567618 0.7737248262474897 0.4390935354912662 1.0 0.8041574081282823 3 P28482,Q06124 2 +Uptake and function of anthrax toxins 0.7096582466567619 0.7737248262474882 0.439093535491267 1.0 0.8041574081282823 3 Q02750,Q8WUM4 2 +Gab1 signalosome 0.7092142006087127 0.7722690041599868 0.4399551194649271 1.0 0.8041574081282823 3 P62993 1 +Met activates ras signaling 0.7090638930163458 0.7717763976935458 0.4402468731000075 1.0 0.8041574081282823 3 P62993,Q96P70 2 +Gap junction trafficking and regulation 0.4772398766471676 0.7673341919598482 0.4428828442609678 1.0 0.8042839181719836 10 P04350,Q9BUF5,P09496 3 +Adherens junctions interactions 0.5149283531751078 0.7636672356006605 0.4450655706488695 1.0 0.8042839181719836 7 P19022 1 +Beta catenin independent wnt signaling 0.3790051672329099 0.7525086956452136 0.4517452025344568 1.0 0.8070308685258051 53 P28074,Q13200,O75832,P07737,Q15008,Q9UBI6,Q92530,P60900,P49721,P63000,Q99436,P28070,O43242,P25786,P28072,P55036,P51665,P25788,P09496 19 +Sumo is conjugated to e1 uba2 sae1 0.7032085561497383 0.7524186534993755 0.451799332379831 1.0 0.8070308685258051 2 Q9UBT2 1 +Processing and activation of sumo 0.7032085561497383 0.7524186534993755 0.451799332379831 1.0 0.8070308685258051 2 Q9UBT2 1 +Sumo is transferred from e1 to e2 ube2i ubc9 0.7032085561497383 0.7524186534993755 0.451799332379831 1.0 0.8070308685258051 2 Q9UBT2 1 +Vasopressin regulates renal water homeostasis via aquaporins 0.5444080649610095 0.7501141889674277 0.453185934553864 1.0 0.8074531118193211 5 P10644 1 +Glucagon signaling in metabolic regulation 0.5444080649610095 0.7501141889674277 0.453185934553864 1.0 0.8074531118193211 5 P10644 1 +Processing of intronless pre mrnas 0.4319450398830124 0.7340949222481016 0.4628908880562044 1.0 0.8094479345494426 17 Q5KU26 1 +Signal attenuation 0.6974739970282329 0.7340804586888859 0.46289970256074 1.0 0.8094479345494426 3 P62993,P28482 2 +Pyroptosis 0.4940912079567198 0.7327917278295554 0.4636854673890471 1.0 0.8094479345494426 8 Q9UQN3,Q9Y3E7,Q9H444,P09429,Q07812 5 +Activation of the ap 1 family of transcription factors 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.8094479345494426 2 P28482 1 +Signaling by activin 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.8094479345494426 2 P28482 1 +Signaling by nodal 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.8094479345494426 2 P28482 1 +Pp2a mediated dephosphorylation of key metabolic factors 0.6965824665676087 0.7312051317797061 0.4646538661051009 1.0 0.8094479345494426 3 Q14738,P30154 2 +Defective cftr causes cystic fibrosis 0.3774626480240961 0.7308524849029145 0.4648692612647136 1.0 0.8094479345494426 44 P51665,Q15008,Q13438,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Apc c mediated degradation of cell cycle proteins 0.3748487529864438 0.728773312678907 0.4661403387759841 1.0 0.8094479345494426 57 P28074,Q13200,Q12834,O75832,Q16763,Q15008,Q92530,P60900,P49721,Q99436,Q13309,P28070,O43242,P25786,P28072,P55036,P51665,P25788,P06493 19 +Ovarian tumor domain proteases 0.4800323661403919 0.7286010464031214 0.4662457382387202 1.0 0.8094479345494426 9 Q6GQQ9,Q9Y6K9,P06493 3 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5802827456663554 0.7252482994996439 0.4682997167867184 1.0 0.8107186219094361 4 O00459 1 +Response of eif2ak1 hri to heme deficiency 0.6927233645106201 0.7188008223939063 0.4722636508911613 1.0 0.8126009517490996 3 P05198 1 +Signaling by receptor tyrosine kinases 0.3745622690366331 0.7187728395633507 0.4722808950336647 1.0 0.8126009517490996 125 Q9UBC2,Q16543,P62993,P61201,P52434,P46934,P16949,P05556,Q13685,P78536,P04792,Q96P70,Q93050,O14964,Q07812,P49768,P35269,Q92542,P63000,Q02750,Q96JJ3,O43865,P07900,P11047,Q15904,Q9Y6W5,O00459,Q13177,Q9UNE7,P42566,Q96J02,Q9Y487,P11233,P06756,P28482,P07942,P46108,P30154,Q9UQB8,P09496,O14786 41 +Phase i functionalization of compounds 0.4342828729850491 0.7158608801203299 0.4740772560119737 1.0 0.81469155189469 15 O43169,O00170,Q16850,P07099 4 +Ca dependent events 0.5000471284482474 0.7055028384319234 0.4804973661629079 1.0 0.8153671929755452 7 P52292,P10644 2 +Irak1 recruits ikk complex 0.6883801875788216 0.7049239329375137 0.4808575753445518 1.0 0.8153671929755452 3 Q9Y6K9 1 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.6883801875788215 0.704923932937513 0.4808575753445523 1.0 0.8153671929755452 3 Q9Y6K9 1 +Activated tak1 mediates p38 mapk activation 0.6883801875788215 0.704923932937513 0.4808575753445523 1.0 0.8153671929755452 3 Q9Y6K9 1 +Rho gtpases activate iqgaps 0.4495978756691255 0.6968201726179001 0.4859153400554219 1.0 0.8229495023375301 11 P04350,Q9BUF5,Q13885,Q86VI3 4 +Mitotic g2 g2 m phases 0.346928304485752 0.6927947854260422 0.4884383451392804 1.0 0.825778461514214 93 Q15691,P28074,Q13200,O75832,P23258,Q13409,Q15008,P04350,Q92530,P60900,P49721,Q13561,P63151,P08238,P28070,Q99436,Q9BUF5,O43242,P07900,P25786,P28072,P41208,P55036,P51665,O94927,Q7Z4H7,P20618,P43034,P25788,P06493,P07437,Q13885,Q15154,P30154,Q14203 35 +Budding and maturation of hiv virion 0.4373190727791677 0.689464876187185 0.4905307692020622 1.0 0.8264819301827554 13 Q9UQN3,Q9Y3E7,Q9H444,Q8WUX9,Q8WUM4,Q96PU5 6 +Prolonged erk activation events 0.4831609003224653 0.6886100139224626 0.4910687176280477 1.0 0.8264819301827554 8 P28482,Q02750,P46108,P36507,P27361 5 +Regulation of insulin secretion 0.4278152982841114 0.6719126274096711 0.5016393210353964 1.0 0.8394536433059554 14 P11166,O43865,P10644,P63096 4 +Folding of actin by cct tric 0.4776785714285732 0.6666728900959488 0.5049810989779508 1.0 0.8419918971846387 8 P40227,P49368,P50991,P50990,P48643,P17987,Q99832 7 +Sars cov 1 infection 0.4235099013586243 0.6610931431129141 0.508552582364115 1.0 0.8432096891703594 15 Q9UQN3,Q9Y3E7,Q9H444,Q8WUX9,Q10472 5 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.3764645723925322 0.6601739423660212 0.509142212131898 1.0 0.8432096891703594 41 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,Q96J02,P55036 16 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.4970759064555765 0.657952608067159 0.5105685844514256 1.0 0.8443325000822163 6 Q9UBI6,P10644,P46940 3 +Rhof gtpase cycle 0.4127236058508528 0.6476790102863569 0.5171925827846824 1.0 0.8512759510312943 18 Q07960,Q9NSV4,P47756,O00459,P43121 5 +Dna replication pre initiation 0.360397244584226 0.6376542576759652 0.5236987679209975 1.0 0.8561246624865123 65 P28074,Q13200,Q13416,O75832,P49642,Q15008,Q92530,P60900,P49721,Q9UJA3,Q99436,P28070,Q14974,O43242,P25786,P28072,Q9NR33,Q9NRF9,O75419,P55036,P51665,P20618,P25788,Q9Y619,O60684,P52294 26 +Myoclonic epilepsy of lafora 0.6678550207962042 0.6317157115368889 0.5275726595888384 1.0 0.8592946798871567 2 P46976 1 +Adora2b mediated anti inflammatory cytokines production 0.4548881041285346 0.6238012238243934 0.5327581358269626 1.0 0.8617424224666539 9 P10644,P63096 2 +Biosynthesis of specialized proresolving mediators spms 0.6611739095226821 0.6201951496852669 0.5351293144183848 1.0 0.8624599920997164 3 P34913 1 +Glycogen synthesis 0.5072851620576948 0.6172222198850194 0.5370881616107763 1.0 0.8624599920997164 5 P13807,P36871,P46976,Q16851 4 +Fceri mediated mapk activation 0.4636970564585999 0.6114920317704546 0.5408738919199274 1.0 0.8624599920997164 8 P62993,P28482,Q13177,P63000 4 +Adp signalling through p2y purinoceptor 12 0.5461120048146878 0.6100906048545838 0.5418017899087961 1.0 0.8624599920997164 4 P63096 1 +Gaba receptor activation 0.5461120048146878 0.6100906048545838 0.5418017899087961 1.0 0.8624599920997164 4 P63096 1 +Gaba b receptor activation 0.5461120048146878 0.6100906048545838 0.5418017899087961 1.0 0.8624599920997164 4 P63096 1 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4246126340881604 0.6055817531983947 0.5447925219952023 1.0 0.8652955324035069 12 P40227,P78371,P49368,P29992,P50991,Q9UBI6,P67870,P50990,P48643,P17987,Q99832 11 +Oncogene induced senescence 0.4731965767601537 0.6033998078475602 0.5462427500326215 1.0 0.8656036354918741 7 P28482,P42771,P06400 3 +Regulation of plk1 activity at g2 m transition 0.3765243355846923 0.600491636377895 0.5481786331605067 1.0 0.8657580175344378 37 Q15691,P04350,O94927,Q7Z4H7,P43034,P07900,P06493,P07437,Q15154,P41208,Q13561,Q14203,Q13409 13 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4482795145092977 0.5968589269441723 0.5506015715604791 1.0 0.8657580175344378 9 P27348,P62258,P63104,P06493 4 +Ticam1 rip1 mediated ikk complex recruitment 0.5420213195501771 0.5967764682973162 0.5506566308107215 1.0 0.8657580175344378 4 Q9Y6K9 1 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.397123139848773 0.5896849044749793 0.5554019174990297 1.0 0.8702949689382117 21 P10619 1 +Uch proteinases 0.3600091175964028 0.5859342346668054 0.557919710333104 1.0 0.8717759064841942 46 P51665,Q15008,Q8NB78,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,Q92530,P60900,P49721,P55036 16 +Regulated necrosis 0.3963631502492892 0.5798235229781404 0.5620336329120357 1.0 0.8755031005383588 20 Q9UQN3,Q9Y3E7,Q9H444,P09429,O00560,O75955,P07900,Q16543,Q8WUX9,Q8WUM4,Q07812,Q9UNE7 12 +Cyclin d associated events in g1 0.4231337292962314 0.5794532558593858 0.5622833785620611 1.0 0.8755031005383588 11 Q13309,P06400,P63208,P42771,P30154,P63151 6 +Er to golgi anterograde transport 0.34369926058568 0.576737431952156 0.5641168418798626 1.0 0.8755031005383588 77 Q14746,P47756,O15027,O60763,Q13409,P04350,P49755,Q96FJ2,O43237,Q12907,Q13561,P53634,P54920,P56962,Q08379,P52907,Q9BUF5,O43731,Q9H9E3,Q9Y678,P48444,P35606,Q13885,Q92734,Q14203 25 +Signaling by flt3 fusion proteins 0.4953897920509148 0.5764103877281482 0.5643378247772184 1.0 0.8755031005383588 5 Q15643 1 +Integrin signaling 0.4942202384121949 0.5724516068280524 0.5670160620628164 1.0 0.876625478906722 5 P62993 1 +Platelet aggregation plug formation 0.4942202384121949 0.5724516068280524 0.5670160620628164 1.0 0.876625478906722 5 P62993 1 +Glycerophospholipid biosynthesis 0.3780293974435667 0.5665214213452352 0.5710393751073923 1.0 0.876625478906722 32 Q8IV08,Q8NCC3 2 +Interleukin 2 family signaling 0.4922460526201834 0.5657920742138045 0.571535134986223 1.0 0.876625478906722 5 O00459 1 +Diseases of mismatch repair mmr 0.6422770920007483 0.5638598836162306 0.572849493510156 1.0 0.876625478906722 3 P43246 1 +Purine ribonucleoside monophosphate biosynthesis 0.4400119083060594 0.5635681686906422 0.5730480550221966 1.0 0.876625478906722 9 P30520,P22102,P49915,O15067,Q06203,P31939,P30566,P22234 8 +Protein folding 0.371462330776869 0.552574366896717 0.5805548983673523 1.0 0.8789636132381871 36 Q99471,P04350,Q99426,P04062,O75347,Q9UBI6,Q9BUF5,P67870,O95302,Q13885 10 +Copi mediated anterograde transport 0.3550392379695429 0.551972196513929 0.5809674024822205 1.0 0.8789636132381871 56 Q14746,O15498,P47756,O60763,Q8N6T3,Q13409,P04350,P49755,Q96FJ2,O43237,Q9Y6G9,Q13561,P54920,Q08379,P52907,Q9BUF5,O43731,Q9H9E3,Q9Y678,P48444,Q13885,P35606,Q9UJW0,Q14203 24 +Assembly of the orc complex at the origin of replication 0.4465696487587133 0.5456221567050279 0.5853256907656164 1.0 0.8836529783171241 8 Q9Y619,O60684,Q13416 3 +Ikk complex recruitment mediated by rip1 0.484490448124951 0.5399160242814551 0.5892549464233039 1.0 0.8886293714052831 5 Q9Y6K9 1 +Rhov gtpase cycle 0.3931058023842089 0.5293677665229685 0.5965503540883748 1.0 0.896741645760255 17 P06753,P29317,P67936 3 +Selective autophagy 0.3724108927791206 0.5233314204763099 0.6007436392387953 1.0 0.8973183203027573 31 P04350,Q9NS69,P54619,P61088,Q9BUF5,O43237,P67870,O60664,Q13885,Q8N4H5,Q13409 11 +Cytochrome c mediated apoptotic response 0.5184520141680705 0.5223771079130839 0.6014077915989278 1.0 0.8973183203027573 4 P28482,Q9NR28 2 +Formation of apoptosome 0.5184520141680705 0.5223771079130839 0.6014077915989278 1.0 0.8973183203027573 4 P28482,Q9NR28 2 +Signaling by tgf beta receptor complex 0.3863889332890301 0.5212864511188373 0.6021672380131409 1.0 0.8974976668476113 19 Q96PU5,Q9Y624 2 +Intracellular signaling by second messengers 0.3276294542628822 0.5192666742119079 0.6035747896056134 1.0 0.8986415743438825 89 P28074,Q13200,P67870,O75832,P84095,P62993,P46934,Q15008,Q92530,P60900,P49721,Q96B36,P63000,P28070,Q99436,O43865,O43242,P25786,P28072,O00459,Q9UNE7,P55036,P10644,Q8N122,P28482,P51665,P20618,P25788,P52292,Q15382 30 +Biological oxidations 0.3514098245176222 0.5163880667969238 0.6055833986053958 1.0 0.8987728241458517 45 O00170,Q16850,Q9UJ14,P07099 4 +Phosphorylation of emi1 0.5153686519852457 0.5129583589995588 0.6079804492805456 1.0 0.8987907204820774 4 Q12834 1 +Sema4d in semaphorin signaling 0.4474157746080469 0.5097821307239753 0.6102041059500458 1.0 0.9004314388126574 7 P60660,P35579,P63000 3 +E3 ubiquitin ligases ubiquitinate target proteins 0.3865865399338192 0.5079395884407673 0.6114957103273628 1.0 0.9008814032524842 18 P04439 1 +Processing of capped intronless pre mrna 0.383611882236557 0.5062821650467875 0.6126585814651901 1.0 0.9016484783827328 19 Q5KU26 1 +Synthesis of diphthamide eef2 0.6208279150828973 0.5028067980644929 0.6151001136458678 1.0 0.9042937796427208 3 Q9H2P9 1 +Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.6253713606654868 0.4986592651382416 0.6180194461851662 1.0 0.9066131991384376 2 P12814 1 +Regulation of signaling by cbl 0.443855343630985 0.4972614915391284 0.6190046635387287 1.0 0.9066131991384376 7 P62993,O00459 2 +Myd88 independent tlr4 cascade 0.3797304192483589 0.4966558694639851 0.6194317475851698 1.0 0.9066131991384376 22 P05067,P09429 2 +Regulation of mrna stability by proteins that bind au rich elements 0.3465826433111068 0.496224175956981 0.6197362558275483 1.0 0.9066131991384376 62 P28074,Q13200,O75832,Q15008,P04792,P39687,Q92530,P60900,P49721,P63104,Q99436,P28070,O43242,P25786,P28072,P55036,P51665,P25788,Q01105 19 +Cytosolic trna aminoacylation 0.378475336322881 0.4959829208211487 0.619906460949359 1.0 0.9066131991384376 23 P54136,P49591,Q13155,P26640,P49588,Q9P2J5,P26639,O43324,P56192,O43776,P41252,Q9NSD9,Q9Y285,Q12904,P47897,P54577,P14868,P07814,P41250,Q15046,P49589,P23381 22 +Downregulation of erbb2 signaling 0.4490389017980463 0.4882349842337646 0.625383407256217 1.0 0.9080023824071652 6 Q9UNE7,P07900 2 +Nervous system development 0.4082837589861848 0.4819808321982123 0.6298195627815373 1.0 0.9125558990147352 222 Q92859,P27635,A0MZ66,Q12959,Q92542,Q02750,O94813,O43242,P07900,P25786,P35268,P06756,P07942,Q15375,Q16850,P63173,P29317,O14786,P13591,P15311,Q13200,O75832,P07737,P08708,Q9Y6N7,P60660,P05556,Q15008,Q96P70,Q13617,Q92530,Q13740,P49721,P46782,P62273,P63000,P62888,P28070,P11047,P28072,O00459,P55036,P35080,P51665,P28482,P20618,P25398,P30050,P46783,P23396,P28074,O00560,P67870,Q14118,Q16512,P08865,P23528,Q8TEY7,P62829,P35579,P42766,P60900,P49768,P62913,P61513,P09496,P62266,P62993,P04350,P60866,Q9UIW2,P08238,O15143,Q99436,Q9BUF5,Q13177,P25788,Q13885 78 +Golgi to er retrograde transport 0.3365269705712675 0.4682735636559879 0.6395889710839087 1.0 0.9201165729373826 73 O15260,Q9H2M9,P04350,Q9Y678,Q8TD16,Q9BUF5,O43237,P43034,P47756,Q9H0H5,P35606,Q13885,Q10472,Q14203,O43731,P54920,Q13409 17 +Signaling by tgfb family members 0.3751342408831872 0.4628325417946007 0.643484403705334 1.0 0.9217680226551204 20 Q96PU5,Q9Y624 2 +Association of tric cct with target proteins during biosynthesis 0.3743198190756177 0.4584271248962278 0.6466456077619183 1.0 0.9235914886040012 20 P04062 1 +Cd28 co stimulation 0.4124018694217368 0.4563246195575077 0.6481565626233499 1.0 0.9248087539869748 9 P62993,Q13177,O00459,P63000 4 +Toll like receptor tlr1 tlr2 cascade 0.3739571168256356 0.4546848651839356 0.6493359707579698 1.0 0.9253896024332388 19 P05067,P09429 2 +Toll like receptor 9 tlr9 cascade 0.3718286885211576 0.4478354601769417 0.6542719496568417 1.0 0.9298532416766604 21 P05067,P09429 2 +Synthesis of dna 0.3203190831931321 0.4440267449148578 0.6570232477102429 1.0 0.9327205660113054 86 P12004,P28074,Q13200,Q13416,O75832,P63208,Q16763,P49642,Q15008,Q9BRT9,Q92530,P60900,P49721,Q9UJA3,P28070,Q13309,Q99436,O43242,P25786,P28072,Q9NR33,Q9NRF9,O75419,P55036,P51665,P62333,Q9BRX5,P20618,P18858,P25788,Q9Y619,P49005 32 +Flt3 signaling 0.4912579979871147 0.4421193280024016 0.6584028587339881 1.0 0.933734963295474 4 P62993 1 +Signaling by alk in cancer 0.3577020030680963 0.4394875627563918 0.6603082919512293 1.0 0.935492272350682 34 P67936,P62993,Q92734,Q9HC35,P06753,Q14203,P10644 7 +Endosomal sorting complex required for transport escrt 0.3782267237272141 0.4356720928332509 0.6630746562733048 1.0 0.9375535113229212 14 Q9UQN3,Q9Y3E7,Q9H444,Q99816,Q8WUX9,O14964,Q9BRG1 7 +G protein beta gamma signalling 0.5947801096151688 0.4333604542432304 0.664752925248234 1.0 0.9375535113229212 3 Q9UBI6 1 +G beta gamma signalling through cdc42 0.5947801096151688 0.4333604542432304 0.664752925248234 1.0 0.9375535113229212 3 Q9UBI6 1 +Anti inflammatory response favouring leishmania parasite infection 0.3767642623169771 0.4329281474899083 0.665066970491303 1.0 0.9375535113229212 15 P78536,P63096,O43865,Q9UBI6,P10644 5 +Hsf1 activation 0.3815402365582017 0.4325776825669398 0.6653216056383777 1.0 0.9375535113229212 13 Q02790,P04792,Q15185,P07900,P08238 5 +Role of lat2 ntal lab on calcium mobilization 0.5905303977260015 0.422564073905247 0.6726133430028134 1.0 0.940586786430229 3 O00459 1 +Flt3 signaling in disease 0.4207284945220699 0.4187519609420305 0.6753974166173271 1.0 0.9430663412529424 7 Q15643 1 +Phospholipid metabolism 0.3395479700960449 0.4145287346191971 0.6784869275708854 1.0 0.9446267343758922 51 P35790,Q8IV08,Q8NCC3,P67870,Q10713,O00459 6 +Collagen biosynthesis and modifying enzymes 0.3834556263865606 0.4140105725994997 0.6788663639496262 1.0 0.9446267343758922 11 Q32P28,P13674 2 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4406779661017033 0.403590026713063 0.6865142208112298 1.0 0.9507177044530616 5 P17612,Q14738,P30154,P30153 4 +Activation of bad and translocation to mitochondria 0.4191461236081376 0.3924702498270574 0.6947107888963626 1.0 0.9538095418873302 6 P27348,P62258,P63104 3 +Listeria monocytogenes entry into host cells 0.4038629136531229 0.3921104444753536 0.6949766106486743 1.0 0.9538095418873302 8 P62993,P42566 2 +Ptk6 regulates cell cycle 0.5831847890671521 0.3830040853476848 0.7017167349629914 1.0 0.95781868031728 2 P11802 1 +Cytoprotection by hmox1 0.3336699981518314 0.3806838674674664 0.703437841018614 1.0 0.958860901737994 62 P28074,Q13200,P67870,O75832,Q15008,Q92530,P60900,P49721,P33527,Q99436,Q13309,Q8TCT9,P28070,O43242,P25786,P28072,P30043,Q15648,P55036,P51665,P25788 21 +Signaling by pdgfr in disease 0.4070748972959839 0.3749587841836208 0.7076911195139646 1.0 0.9637229212391912 7 O00459 1 +G alpha z signalling events 0.429518794913486 0.3719570603198059 0.7099248200857704 1.0 0.9658279529073852 5 P63096 1 +Striated muscle contraction 0.4288753836524481 0.370175924283423 0.7112514140733945 1.0 0.9666960168044976 5 Q9NYL9,P06753,P67936 3 +Sema4d induced cell migration and growth cone collapse 0.4107674003569401 0.3673141469188298 0.7133847027952176 1.0 0.9677218577048168 6 P35579,P35580,Q13464,P60660,O75116 5 +Polb dependent long patch base excision repair 0.4095776323616906 0.3638072984533316 0.7160019122158141 1.0 0.9686791555262432 6 P09874,P27695,Q9NX46,P18858,P39748 5 +Protein ubiquitination 0.35083790894063 0.3503292274131116 0.726091633070653 1.0 0.974101340155518 25 P04439 1 +Suppression of phagosomal maturation 0.3982782936019425 0.3478679874193765 0.7279393278415289 1.0 0.974101340155518 7 Q14974,P52294,O14964 3 +Negative regulation of met activity 0.3901913256676666 0.3470015910387869 0.7285901234787597 1.0 0.974101340155518 8 P62993,P42566 2 +Adrenaline noradrenaline inhibits insulin secretion 0.5540625436333058 0.3367011618431622 0.7363421874382123 1.0 0.97473383629304 3 P63096 1 +Map3k8 tpl2 dependent mapk1 3 activation 0.4157070958811859 0.3347922519596678 0.7377818056166128 1.0 0.97473383629304 5 Q02750,Q9Y6K9 2 +Golgi cisternae pericentriolar stack reorganization 0.3626447552746666 0.334234973712274 0.7382022547978635 1.0 0.97473383629304 11 P28482,Q08379,P06493,O60763,P27361 5 +Signaling by interleukins 0.3276875619809852 0.3341950541437222 0.7382323758837139 1.0 0.97473383629304 110 P28074,Q13200,P40222,O75832,Q06124,O00170,P62993,Q9Y6K9,P05067,P63208,Q13126,P23528,P05556,Q15008,P61088,Q99460,Q92530,P60900,P49721,P08670,P63104,Q02750,P28070,P52907,Q99436,O43242,P07900,P25786,P51809,P28072,O00459,P51452,Q13177,Q04206,Q14738,P11233,P55036,Q12846,Q15833,P51665,P28482,P62333,P09429,Q53EL6,P20618,Q9UNM6,P25788,P46108,O00231,P30154,P26038,P27361,P30153 53 +G alpha s signalling events 0.4148278633614153 0.3325041348927869 0.7395086179600139 1.0 0.97473383629304 5 P63096 1 +Scavenging by class f receptors 0.4485731272294748 0.3307271932794161 0.7408505598649582 1.0 0.97473383629304 4 P27797,Q92598,P07900 3 +Nephrin family interactions 0.3762639034246335 0.3276338741964749 0.7431885064848909 1.0 0.97473383629304 9 P46940,O00459,Q9Y5K6,O43707 4 +Maturation of sars cov 1 nucleoprotein 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.97473383629304 2 P49840 1 +Tnfr1 induced nfkappab signaling pathway 0.3895890256256678 0.3220338219981325 0.7474270719696792 1.0 0.97473383629304 7 Q6GQQ9 1 +Unwinding of dna 0.3590664229701853 0.3211118519133278 0.748125629017957 1.0 0.97473383629304 11 Q9BRT9,Q9UJA3,O75419 3 +Opioid signalling 0.3479162403427973 0.3209102392242671 0.7482784142275414 1.0 0.97473383629304 19 P28482,P63096,O43865,Q9UBI6,P52292,P30154,P10644 7 +Tp53 regulates transcription of genes involved in cytochrome c release 0.4419126276111942 0.3151652972984644 0.7526361526086498 1.0 0.976864389734246 4 Q07812 1 +Costimulation by the cd28 family 0.3505276254374722 0.315038391876249 0.7527325044169366 1.0 0.976864389734246 15 P63000,P62993,Q16512,O00459,P30154,Q13177,Q14738 7 +Aquaporin mediated transport 0.3910126154275934 0.3113106687748568 0.7555644574763001 1.0 0.9786093157718868 6 P10644 1 +Suppression of apoptosis 0.4041034790365838 0.3053734345331918 0.7600817522662322 1.0 0.9835527927942764 5 P28482,P27361,Q63HN8,P49840 4 +Protein protein interactions at synapses 0.3464158843403313 0.2974612961576225 0.7661143525684642 1.0 0.9848600230585436 15 P10586,Q9UJU6,Q14168,Q12959 4 +Degradation of beta catenin by the destruction complex 0.3251125541568762 0.2966893253816788 0.7667037074095358 1.0 0.9848600230585436 50 P51665,Q15008,Q99436,P28074,Q13200,P28070,O43242,P20618,O75832,P25786,P25788,P28072,Q92530,P60900,P49721,P55036 16 +Negative regulation of mapk pathway 0.3470514285582378 0.2830318550527885 0.7771524181462293 1.0 0.9928976218956848 12 P28482,Q14738,Q02750,P36507,P30154,Q99956,P27361 7 +Metalloprotease dubs 0.4262782401902366 0.2807294978426762 0.7789178821689626 1.0 0.9928976218956848 4 O00487,Q9NXR7,Q9NWV8 3 +Phenylalanine metabolism 0.5359477124183094 0.2770540435451513 0.7817386089112541 1.0 0.9939175285185504 2 P61457 1 +Dna damage reversal 0.3910199226880818 0.2742885530344519 0.7838628806653598 1.0 0.9939175285185504 5 Q6P6C2,Q8N9N2,Q8N3C0,Q9H1I8 4 +Josephin domain dubs 0.5185735512630032 0.2658385326956047 0.7903635658148858 1.0 0.9977129954565648 3 P54727,P54725 2 +Ikba variant leads to eda id 0.5176607283114181 0.2641910906601526 0.7916326758822032 1.0 0.9977129954565648 3 Q9Y6K9 1 +Smooth muscle contraction 0.3409511109737962 0.2576840375330143 0.796650766378693 1.0 1.0 11 Q05682,P67936,Q13177,P60660,P06753 5 +Synthesis of udp n acetyl glucosamine 0.5129271916790507 0.2557920454885009 0.7981114164089997 1.0 1.0 3 Q06210,O95394 2 +Tp53 regulates transcription of cell death genes 0.3826940231935876 0.2557037058714249 0.7981796334110423 1.0 1.0 5 P49327,Q13625,Q9Y255,Q07812 4 +Rho gtpase cycle 0.359045750351227 0.2545007999929541 0.7991086861298993 1.0 1.0 166 Q14126,P05556,Q9BZH6,O60245,Q9NSV4,Q14739,P27105,P84095,Q8NBN3,Q15904,Q86VI3,O00459,P29317,P02786,Q9Y2I1,O75976,P43121 17 +Ub specific processing proteases 0.3111637446816734 0.2455272797602584 0.8060481882827464 1.0 1.0 76 P28074,Q13200,Q12834,O75832,Q9Y6K9,Q8TEY7,Q15008,Q96K76,Q92530,O14964,P60900,O60493,P49721,Q99436,Q13309,P54578,P28070,O43242,P25786,P28072,P55036,P51665,P20618,P25788,Q96FW1 25 +Caspase mediated cleavage of cytoskeletal proteins 0.3649613325401507 0.2452709475378812 0.8062466453178962 1.0 1.0 6 Q13813,P35611,Q14790,Q9UJU6,P08670 5 +Met receptor recycling 0.3765105099783163 0.2425193434512074 0.8083777702458979 1.0 1.0 5 P46108,P20338,P62993 3 +Signaling by kit in disease 0.361944721426646 0.2382399913925851 0.8116949612646609 1.0 1.0 6 O00459 1 +Signaling by erbb2 0.3344015327951036 0.2360774099336723 0.8133726028129031 1.0 1.0 11 P62993,Q9UNE7,P07900 3 +Er quality control compartment erqc 0.3591403738472827 0.2318227976982916 0.8166756493485512 1.0 1.0 6 Q13438 1 +Platelet sensitization by ldl 0.3690635417992418 0.227352392465567 0.8201497362671688 1.0 1.0 5 Q14738,P30154,Q06124 3 +Galactose catabolism 0.5068330362448128 0.2253889677205608 0.8216766933493875 1.0 1.0 2 P51570 1 +Dna replication 0.3017057961189013 0.2126210642872393 0.8316225401759665 1.0 1.0 92 P12004,P28074,Q13200,Q13416,O75832,Q16763,P49642,Q15008,Q9BRT9,Q92530,P60900,P49721,Q9UJA3,P28070,Q13309,Q14974,Q99436,O43242,P25786,P28072,Q9NR33,Q9NRF9,O75419,P55036,P51665,P62333,Q9BRX5,P20618,P18858,P25788,Q9Y619,O60684,P52294,P49005 34 +Activation of bh3 only proteins 0.3239958708981709 0.186586012568751 0.8519852344987613 1.0 1.0 10 P27348,Q96FJ2,P62258,P63104 4 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.465973254086183 0.1856319597091011 0.8527333889271522 1.0 1.0 3 P28482,P27361 2 +Vxpx cargo targeting to cilium 0.3231089934484784 0.184132383700048 0.8539096022801926 1.0 1.0 10 Q9UPT5,Q96KP1,Q8IYI6,O00471,Q92538,Q9NV70,O60645,Q8TAG9,P18085 9 +Diseases of mitotic cell cycle 0.3160405485986792 0.181884067195255 0.8556737084708617 1.0 1.0 14 P46100,Q13042,Q16763,P11802,Q13309,Q9UJX4,Q9H1A4,P06400,Q9UER7,Q9UJX2,P30260,P24941,Q96DE5 13 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3157581173667046 0.1788026815234618 0.8580926396655324 1.0 1.0 11 Q16763,Q13042,P30260,Q9UJX4,Q12834,Q9H1A4,Q9UJX2,O43684,O60566,Q96DE5 10 +Apc cdc20 mediated degradation of nek2a 0.3157581173667046 0.1788026815234618 0.8580926396655324 1.0 1.0 11 Q16763,Q13042,P30260,Q9UJX4,Q12834,Q9H1A4,Q9UJX2,O43684,O60566,Q96DE5 10 +Apc c cdc20 mediated degradation of cyclin b 0.3157581173667039 0.1788026815234598 0.858092639665534 1.0 1.0 11 Q16763,Q13042,Q9UJX4,Q12834,P06493,Q9H1A4,P14635,Q9UJX2,P30260,Q96DE5 10 +Transcriptional regulation by ventx 0.3159463487332394 0.1784125028352651 0.8583990309873082 1.0 1.0 13 Q16763,Q9HCE1,Q13042,P04637,Q9UJX4,Q96DE5,Q9H1A4,P42771,Q9UJX2,P30260,Q04206,P35222 12 +Map2k and mapk activation 0.3148589641927151 0.1762062774238466 0.8601318892803986 1.0 1.0 11 P28482,Q02750,Q9Y2Q5,P36507,P46940,P27361 6 +Fceri mediated ca 2 mobilization 0.3393736547872499 0.1747625646135656 0.8612662046927297 1.0 1.0 5 P62993 1 +Ripk1 mediated regulated necrosis 0.3148314608175263 0.1743428757788626 0.8615960051778637 1.0 1.0 12 O00560,O75955,P07900,Q16543,Q8WUM4,Q9UNE7 6 +Maturation of sars cov 2 nucleoprotein 0.3386856972940925 0.1736942510115208 0.8621057558760647 1.0 1.0 5 Q99873,Q96SB4,P49841,P49840 4 +Synthesis of leukotrienes lt and eoxins ex 0.4530478902938755 0.1704610135632388 0.8646475922715344 1.0 1.0 3 P33527 1 +P75ntr negatively regulates cell cycle via sc1 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 1.0 2 Q92769 1 +Wnt ligand biogenesis and trafficking 0.3331242316278401 0.1653067409139144 0.8687025533327326 1.0 1.0 5 O60493,Q9UBQ0 2 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3156640857653323 0.1641090918454452 0.8696452645948145 1.0 1.0 10 Q16763,Q13042,Q13309,Q9UJX4,Q9H1A4,P06400,Q9UJX2,P30260,Q96DE5 9 +Apoptotic factor mediated response 0.3215306221510721 0.1599653793934565 0.8729083462158143 1.0 1.0 8 P28482,Q9NR28,P42771,Q07812,P27361 5 +Copii mediated vesicle transport 0.3146288279443902 0.158719152470525 0.8738901479709842 1.0 1.0 30 P49755,Q08379,O95487,Q12907,O15027,Q92734,O60763,P53634,P54920,P56962 10 +Robo receptors bind akap5 0.4404160475482931 0.1572897356557045 0.8750165093305384 1.0 1.0 3 P13861,P17612 2 +Acetylcholine regulates insulin secretion 0.4404160475482929 0.1572897356557042 0.8750165093305386 1.0 1.0 3 P29992,P29966 2 +Atf6 atf6 alpha activates chaperone genes 0.4398216939078767 0.156709266148542 0.8754739839850489 1.0 1.0 3 P27797,P25208 2 +Atf6 atf6 alpha activates chaperones 0.4398216939078767 0.156709266148542 0.8754739839850489 1.0 1.0 3 P27797,P25208 2 +Metabolism of nitric oxide nos3 activation and regulation 0.3256021409455897 0.1546624846799136 0.8770874069304875 1.0 1.0 5 P07900,P50570,O75608,Q9Y314 4 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3155701101518258 0.1528797393356841 0.8784931137419905 1.0 1.0 9 Q16763,Q13042,Q9UJX4,Q12834,Q9H1A4,Q9UJX2,P30260,Q96DE5 8 +Mismatch repair 0.3059717349033692 0.1479459133662058 0.882385453249463 1.0 1.0 12 P18858,P43246,Q9UQ84,P52701,P49005 5 +Runx2 regulates osteoblast differentiation 0.3386629049043839 0.145202279923178 0.8845511658944811 1.0 1.0 4 P28482,P06400 2 +Phase ii conjugation of compounds 0.3104649847872166 0.137735100303968 0.8904497777367966 1.0 1.0 29 Q9UJ14 1 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.4146235896498497 0.1351888573146894 0.8924625567919007 1.0 1.0 3 P62993 1 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.3063652587745326 0.1332736219729288 0.893976988098599 1.0 1.0 6 O14920,Q7Z434,Q14258,Q14790,Q9Y6K9 5 +Signaling by robo receptors 0.3293514611988183 0.1329557335815101 0.8942283890889002 1.0 1.0 138 P23396,P28074,Q13200,P62266,P27635,O75832,P07737,P08708,Q14118,Q16512,Q9Y6N7,P08865,Q8TEY7,P62829,Q15008,P60866,Q13617,Q92530,P60900,P49721,P46782,P62273,P63000,P62888,P28070,O94813,Q99436,O43242,P25786,P35268,P28072,Q13177,P55036,P35080,P51665,P62913,P61513,P20618,P25398,P30050,P25788,P46783,P63173,O14786 44 +Assembly of the hiv virion 0.4080237741456185 0.1305002041559704 0.8961706926310395 1.0 1.0 3 Q99816,Q9UK41 2 +Infection with mycobacterium tuberculosis 0.300752079905815 0.1303885059542943 0.8962590598777198 1.0 1.0 14 P28482,Q14974,Q9UI12,P52294,O14964 5 +Response of mtb to phagocytosis 0.300752079905815 0.1303885059542943 0.8962590598777198 1.0 1.0 14 P28482,Q14974,Q9UI12,P52294,O14964 5 +Collagen formation 0.3001310733732247 0.1284059326718431 0.8978277364317435 1.0 1.0 14 Q32P28,P13674 2 +Interleukin 3 interleukin 5 and gm csf signaling 0.2985506311986901 0.1270939048336136 0.8988660755806088 1.0 1.0 12 P46108,O00459,P62993 3 +Calnexin calreticulin cycle 0.2960857897784165 0.1256863644591372 0.8999801958516591 1.0 1.0 11 Q13438 1 +Thrombin signalling through proteinase activated receptors pars 0.2998226019103468 0.1241173950542696 0.9012223253951476 1.0 1.0 5 P28482,Q9UBI6 2 +Regulation of localization of foxo transcription factors 0.3105365544074835 0.1215602872155288 0.9032472663821668 1.0 1.0 4 P63104 1 +Activation of nima kinases nek9 nek6 nek7 0.3091557669441075 0.1206147565144732 0.9039961801708156 1.0 1.0 4 P14635,Q8TD19,P06493 3 +Clec7a inflammasome pathway 0.3986928104575242 0.1196745146145484 0.9047409896304794 1.0 1.0 2 Q04206 1 +Fcgr3a mediated il10 synthesis 0.3010050068631201 0.118915013712303 0.9053426869415118 1.0 1.0 8 P10644 1 +Regulation of tp53 activity through methylation 0.3824665676077286 0.1156625168809366 0.9079200140117194 1.0 1.0 3 O14744,O96017 2 +Gp1b ix v activation signalling 0.3835412953060107 0.1135075609574937 0.9096281690464888 1.0 1.0 2 P63104 1 +Ion homeostasis 0.2895442359249439 0.1097857797907558 0.912579268951008 1.0 1.0 11 P05023,O43865,P17612,Q13555,P20020,P54709,P30626,P23634,P17252,Q12797 10 +Cardiac conduction 0.2895442359249439 0.1097857797907558 0.912579268951008 1.0 1.0 11 P05023,O43865,P17612,Q13555,P20020,P54709,P30626,P23634,P17252,Q12797 10 +Type i hemidesmosome assembly 0.3646359583952472 0.1080730736593915 0.91393772713605 1.0 1.0 3 P23229,Q03001 2 +Assembly of collagen fibrils and other multimeric structures 0.3646359583952472 0.1080730736593915 0.91393772713605 1.0 1.0 3 P23229,Q03001 2 +Glycerophospholipid catabolism 0.3535353535353613 0.1052765015072323 0.9161564084260378 1.0 1.0 2 Q8IY17 1 +Traf3 dependent irf activation pathway 0.3532382650029825 0.1052168097651423 0.9162037724951352 1.0 1.0 2 Q14258 1 +Traf6 mediated induction of tak1 complex within tlr4 complex 0.3511586452763009 0.1048092074222727 0.9165272038265692 1.0 1.0 2 Q6SZW1 1 +Nf kb is activated and signals survival 0.3440285204991168 0.1035413906717356 0.9175333010008352 1.0 1.0 2 Q04206 1 +P75ntr signals via nf kb 0.3440285204991168 0.1035413906717356 0.9175333010008352 1.0 1.0 2 Q04206 1 +Rap1 signalling 0.2743757431628961 0.1024749602260834 0.9183796870486018 1.0 1.0 4 P17612,P17252,P63104 3 +Fbxw7 mutants and notch1 in cancer 0.3229352346999498 0.1007928817486601 0.9197148776061526 1.0 1.0 2 P63208 1 +Ion transport by p type atpases 0.2892857142857165 0.0987641205556739 0.9213255568166958 1.0 1.0 8 P05023,Q13555,P20020,P54709,P30626,P23634,Q9HD20 7 +Synthesis of ip3 and ip4 in the cytosol 0.3280832095096603 0.0980550120549284 0.9218886104874608 1.0 1.0 3 P19174,Q01968 2 +Synthesis of ip2 ip and ins in the cytosol 0.3263001485884123 0.0977196103307943 0.922154943291504 1.0 1.0 3 Q01968,Q9NPH2 2 +Enos activation 0.325408618127788 0.097556387514483 0.9222845569665168 1.0 1.0 3 O75608,P07900 2 +Prolactin receptor signaling 0.3230312035661241 0.0971353746236636 0.9226188887897376 1.0 1.0 3 P63208,Q06124 2 +Disinhibition of snare formation 0.3075780089153067 0.0948597901658812 0.9244261952431436 1.0 1.0 3 P17252,Q12846 2 +Pre notch processing in the endoplasmic reticulum 0.3004457652303142 0.0940461629923123 0.925072486446226 1.0 1.0 3 Q04721,Q9H488 2 +Methionine salvage pathway 0.296879643387818 0.093687697942828 0.9253572429111816 1.0 1.0 3 P17174,Q13126 2 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.257057949479943 0.0913025625540934 0.92725218187184 1.0 1.0 3 P28482,P27361 2 +Trna modification in the nucleus and cytosol 0.2788809150627778 0.0858067337461849 0.9316200534692428 1.0 1.0 11 Q96PZ0,P57081,Q08J23 3 +Neurexins and neuroligins 0.2830135328808888 0.0855813031383912 0.931799261855628 1.0 1.0 9 Q14168 1 +Rho gtpases activate paks 0.2837282595685597 0.0832240111800104 0.9336734208043812 1.0 1.0 13 P35579,Q14247,P63000,Q16512,Q13177,P60660 6 +Condensation of prophase chromosomes 0.2810057753163892 0.0825440800258772 0.9342140671147 1.0 1.0 12 Q01105,Q6IBW4 2 +Deadenylation of mrna 0.2839947744700705 0.0800407217898638 0.9362048685433102 1.0 1.0 14 P23588,Q9HBH5 2 +Cd209 dc sign signaling 0.2474411535739429 0.0719208224931805 0.9426649190062352 1.0 1.0 6 Q16512,Q13177 2 +Cyclin a b1 b2 associated events during g2 m transition 0.2741380597217399 0.0706660172002309 0.9436635675420004 1.0 1.0 9 P63151,P06493 2 +Signaling by moderate kinase activity braf mutants 0.2750297973778314 0.06893177570524 0.9450439253114666 1.0 1.0 12 P28482,Q9Y490,Q02750,P30086,Q13555,P46940,P36507,P18206,P35232,P41240,P27361 11 +Rho gtpases activate wasps and waves 0.2905893073694556 0.0684440162542119 0.9454321840541926 1.0 1.0 19 P28482,Q96F07,P63000,Q9NZQ3,Q9UQB8,P62993,Q9Y6W5,O15143 8 +Deubiquitination 0.2883670691633284 0.0650654942814679 0.9481218537674132 1.0 1.0 93 Q6GQQ9,P28074,Q13200,Q12834,O75832,Q9Y6K9,Q8TEY7,Q15008,Q8NB78,Q96K76,Q92530,O14964,P60900,P49721,O60493,P28070,P54578,Q13309,Q99436,O43242,P25786,P28072,P55036,P51665,P20618,P25788,P06493,P45974,Q96FW1 29 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.2636904761904785 0.0629172553371367 0.9498323942951648 1.0 1.0 8 P04637,Q99873,P12004,O14965,P06493,P14635,Q07812 7 +Vegfr2 mediated vascular permeability 0.2627876944844718 0.0537030841779541 0.9571717255313004 1.0 1.0 9 Q13177,P07900,P63000 3 +Signaling by scf kit 0.2578830740538123 0.045449747626059 0.9637488290566982 1.0 1.0 10 O00459 1 +Metabolism of porphyrins 0.253356015770144 0.038253874223604 0.969485266881882 1.0 1.0 11 P33527 1 +Platelet homeostasis 0.2519356759976142 0.0369669531343532 0.970511355299302 1.0 1.0 10 P23634,Q9UBI6,Q06124,P20020,P30154,P30626,P16615,Q14738,P30153 9 +Regulation of tp53 expression and degradation 0.2520107238605985 0.0361288847111939 0.971179590688589 1.0 1.0 11 P04637,Q9UER7,P06493,P42771,P30154,O96017,Q93009,P24941,P42345,P30153 10 +Programmed cell death 0.2919316910237975 0.0345941117829763 0.9724033968077292 1.0 1.0 101 Q14126,Q9UQN3,Q9H444,Q9Y3E7,P28074,Q13200,O00560,P26583,Q9UJU6,O75832,Q16543,P42771,Q15008,P62258,Q96FJ2,Q8WUX9,Q92530,Q8WUM4,Q07812,P49721,P60900,P63104,P28070,Q99436,Q14974,O75955,O43242,P07900,P25786,P27348,P28072,Q9P289,Q13177,Q9UNE7,P55036,Q14254,P51665,P28482,Q9NR28,O00429,P09429,P20618,P25788,P52294 44 +Piwi interacting rna pirna biogenesis 0.2367575966396566 0.0182948236833785 0.9854036568790324 1.0 1.0 10 P52434,Q9Y2W6 2 +Nuclear events stimulated by alk signaling in cancer 0.2333774208727714 0.0104616440607599 0.9916529679817884 1.0 1.0 11 Q9HC35,P28482,P33176,P63208 4 +Regulation of expression of slits and robos 0.307136772652772 0.0082475252863645 0.9934195015120162 1.0 1.0 124 P28074,Q13200,P62266,P27635,O75832,Q14118,P08708,Q9Y6N7,P08865,Q8TEY7,P62829,Q15008,P60866,Q13617,Q92530,P60900,P49721,P46782,P62273,P62888,P28070,O94813,Q99436,O43242,P25786,P35268,P28072,P55036,P51665,P62913,P61513,P20618,P25398,P30050,P25788,P46783,P63173,P23396 38 +Copi dependent golgi to er retrograde traffic 0.2865152064826539 0.0079873849751251 0.9936270566110764 1.0 1.0 48 O15260,P04350,Q9Y678,Q9BUF5,Q9H0H5,P35606,O43731,P54920 8 +Diseases of dna repair 0.2072467859100269 0.0014898412274589 0.9988112791263156 1.0 1.0 9 P43246,Q9UQ84 2 +Amino acids regulate mtorc1 0.2447093889716883 8.564162838414795e-05 0.9999316678670338 1.0 1.0 13 Q6IAA8,Q8N122,P36543,P21281,P21283,P38606,Q9Y2Q5,Q9UI12,Q15382,Q96EE3,P42345,P61421 12 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0198fe131bae4ffc2f3456619c0dbc4965a36460 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell death genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by membrane tethered fusions of pdgfra or pdgfrb", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCKDHA", "BCKDHB", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRD1", "BRD2", "BRD4", "BRD7", "BRPF1", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CDS2", "CENPF", "CENPI", "CEP290", "CERS1", "CERS2", "CETN2", "CFL1", "CGN", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "COASY", "COG2", "COG4", "COG5", "COG7", "COLEC12", "COLGALT1", "COMMD3", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FOXK1", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP2", "HECTD1", "HECTD3", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "IKBKG", "ILF2", "ILK", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INCENP", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRP1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYN", "LYPLA1", "LZTFL1", "M6PR", "MAGED2", "MAGT1", "MAIP1", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL14", "MFAP1", "MFGE8", "MFN1", "MFN2", "MGA", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MLEC", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO5A", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NEO1", "NET1", "NF2", "NFS1", "NFYB", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRP1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP2", "NUCB1", "NUDC", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCK2", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "POFUT1", "POFUT2", "POGLUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIPK1", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLIT2", "SLK", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPOPL", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX17", "STX18", "STX4", "STX5", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE1", "SYNE2", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM30A", "TMEM87A", "TMF1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRMT10C", "TRMT6", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGGT2", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WBP11", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WFS1", "WIPI2", "WNK1", "XAB2", "XPC", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZFYVE16", "ZNF512B", "ZNF638", "ZW10", "ZZZ3"], "leading_proteins": ["AAMP", "AARS", "ABCB1", "ABCB6", "ABCC1", "ACBD3", "ACTN1", "ACTN4", "ACTR1A", "ADAM17", "ADD1", "ADGRE5", "ADPRHL2", "ADSL", "ADSS", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AKT1S1", "ALCAM", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC5", "ANP32A", "APEX1", "APLP2", "APP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARHGAP1", "ARL3", "ARPC1B", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASPH", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B4GAT1", "BABAM1", "BABAM2", "BAIAP2", "BAX", "BICD2", "BLVRB", "BRD2", "BSG", "BUB1B", "BUB3", "CAB39", "CALD1", "CALR", "CALU", "CAMK2G", "CAPZA1", "CAPZB", "CARS", "CASP8", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC45", "CDH2", "CDK1", "CDK2", "CDK4", "CDKN2A", "CETN2", "CFL1", "CHEK2", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP7", "CLCN3", "CLTA", "COG2", "COG4", "COLEC12", "COPB2", "COPG1", "COPS2", "COPS5", "COPS6", "COPS7B", "CPD", "CRK", "CSK", "CSNK2B", "CSTB", "CTNNB1", "CTSA", "CTSC", "CTTN", "CUL2", "CXADR", "CYB5B", "CYFIP2", "CYP51A1", "DAG1", "DARS", "DAXX", "DBNL", "DCAF1", "DCTN1", "DCTN2", "DCTN4", "DDA1", "DHCR24", "DHCR7", "DIABLO", "DIAPH3", "DLG1", "DNAJA1", "DNAJA2", "DNASE2", "DNM1L", "DNM2", "DOHH", "DPH5", "DSC2", "DSC3", "DSG2", "DST", "DUSP3", "DUSP9", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL2", "ECE1", "EEF1E1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELMO2", "EMB", 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2.380735528549487 0.0172781117023785 18.929611650485437 83.0752427184466 0.8523996335219438 0.5089902911900335 9.09856474570077 6.061710858604258 1.0800674607776464 0.3865214102951685 0.2140056698765613 0.2497517831337832 0.3019629878316038 0.2035199245635404 0.0013981409421044 +Primary focal segmental glomerulosclerosis fsgs 6 21 2.376239630373909 0.0174901001393108 4.497572815533981 18.5995145631068 -0.0498192290963992 0.5829800426962075 3.120165220301555 1.925127598162104 0.8734481917322797 0.2898073783973391 0.080787090338714 0.0327224420542492 0.0191373699896123 0.0027943802514918 0.0219335059982234 +Proteasome degradation 18 42 2.2963699531280817 0.0216547374586641 12.050970873786408 41.16504854368932 0.6913339882315582 0.5158259179783452 5.889337413827548 1.124286935861288 1.1356581007954978 0.3607938079641982 1.0 1.0 0.0891217330395956 0.0014327621348651 0.0001452325992069 +Splicing factor nova regulated synaptic proteins 2 18 2.246612650502344 0.0246647929861159 4.776699029126213 15.150485436893204 -0.2758516323768686 0.5913314208771131 2.7489875941720214 2.1125318995193765 0.7784992183301543 0.2875817435057189 0.0230572634873926 0.0087935329278829 0.0325598174288622 0.0329460998536745 0.1659016353191164 +Complement system in neuronal development and plasticity 2 14 2.1999868318992446 0.0278078293065557 2.9563106796116503 10.305825242718448 -0.0407414562652891 0.5874540694178116 2.110545408868441 2.54735062226637 0.8496208467087996 0.3054012624293282 0.0668350320040178 0.2260688267312995 0.0142951840993497 0.1335053000482259 0.4687829092097882 +Alzheimers disease and mirna effects 23 88 2.1787301854635976 0.0293517179709703 19.78640776699029 84.62864077669903 0.8675405351918691 0.5019659822826982 9.06411947478317 6.212690980603589 1.0744065053186531 0.3869842050583563 0.2203922842647054 0.2552254179082389 0.3100332756868921 0.2139557953645005 0.0016809123628817 +Cholesterol biosynthesis with skeletal dysplasias 3 6 2.1524312671873664 0.0313634032922534 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 1.0 1.0 0.0666860823201616 1.1471144328347477e-05 0.0001735559058557 +Statin inhibition of cholesterol production 2 7 2.1365090555090256 0.0326379436624977 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.0055914837945719 0.0020655426456597 0.0003080716102714 0.0042908003473226 0.0037759888499611 +Sphingolipid metabolism in senescence 2 13 2.109099145680175 0.0349360245967818 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.0148267428903527 1.0 0.0210734332562196 0.017764157863851 0.0236194052560011 +Folate metabolism 1 14 2.074214741307633 0.0380593717715587 2.9223300970873787 14.66504854368932 0.4885827184030638 0.4716393281670001 2.01903235685469 1.6964960312512605 0.9273691097933516 0.2947258147319118 0.2429761091428759 0.1541506060207377 0.0435975481844182 0.2012424218570439 0.4989028149926751 +Ferroptosis 4 26 2.056227617315141 0.0397605814454826 6.247572815533981 23.589805825242717 0.9586016481897424 0.3324276931898122 2.8577723913591164 2.1450310521583007 1.2134257594151 0.3161491716459103 0.0645963387267349 0.2222355866483168 0.0891217330395956 0.0078507588763973 0.0112872973833843 +Copper homeostasis 1 6 2.044230080670555 0.0409308228338076 2.424757281553398 7.135922330097087 0.5903026015483873 0.4117931054097133 1.5206247723778896 1.8697829357915037 1.0031617247546825 0.3013602819658685 0.2793343331559579 0.1788224008957527 0.3263246311566628 0.6287574181217924 0.5873216584654045 +Selenium micronutrient network 1 12 2.0270396995705378 0.0426583528323991 2.7766990291262137 11.762135922330096 -0.024819515047186 0.5435700665428025 2.3020971394608045 1.5206422062369562 0.8512283156860216 0.2707389391754307 0.2852239797067621 0.1828652209005429 0.0609936469852355 0.2646794233181401 0.6008853076934467 +Metapathway biotransformation phase i and ii 4 22 1.982020885816664 0.0474769031151325 5.674757281553398 21.74757281553398 1.0367643596879972 0.3247805075973627 2.26648088910968 1.8784337960788755 0.9302956939670612 0.2816826074355951 0.0856229888655945 0.2560754722464486 0.1170412325774002 0.0153040129106345 0.167212369248385 +Development of ureteric collection system 2 5 1.972908261371341 0.0485060152247951 2.121359223300971 4.502427184466019 -0.1848819296721689 0.5528649962119888 1.334686646285994 0.8632147704039412 0.8677792676762702 0.3025180950966701 0.2910660683117588 1.0 0.339526513295544 0.0824073873197279 0.3363841302805421 +Oxysterols derived from cholesterol 1 6 1.971111662219495 0.0487111050772708 2.254854368932039 7.33252427184466 0.1962044165430426 0.4767358733288924 1.826344624524478 1.1378784708655931 1.058988657917013 0.30869858242651 0.1298272630870375 1.0 0.1543818096433915 0.0635022977163126 0.1998160014011807 +Pregnane x receptor pathway 0 5 1.966925625926467 0.0491917857226342 1.1893203883495145 4.766990291262136 0.5016334176412254 0.4430864332327935 1.2160266844733736 0.6855496483071739 1.011470017110033 0.3166911340775686 0.1081933924999157 0.066549445548378 0.1289666473793992 0.2927467368934597 0.5034522087350044 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cc020fe2f7077e580d717567dcc15d95920dda30 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 609, + "title": "Average number of proteins per term", + "value": 11.178981937602627 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ee3a3a9d82c87cadd37464d55e105354275dd39f --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..49202557969c35cb2196a0a0faa7ad4fdd95c289 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,243 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ebola virus infection in host 0.7133481916736375 3.181788630784318 0.00146368597293 0.5901802083459554 0.2166807274572664 43 P05556,P01889,P78536,P05198,O15118,Q08431,P61916,O00459,P04439,P42566,P10321,P06756 12 +Degradation pathway of sphingolipids including diseases 0.9742874094249896 2.5210011661726743 0.0117021464254252 0.9992296253953716 0.3327372742403233 6 P17900,P06865,P16278,P06280 4 +Allograft rejection 0.8665677552406928 2.4828075969582692 0.0130351472645127 0.9996613684386476 0.3327372742403233 10 P08183,P01889,P04439 3 +7oxoc and 7betahc pathways 0.9064104389619764 2.438413252658931 0.0147518988579453 0.999882706383998 0.3327372742403233 8 P34913,P61916,O15118 3 +Pi3kakt signaling pathway 0.5938459946739044 2.4178578082572746 0.0156121762434562 0.9999310973427936 0.3359254451604929 44 Q16543,P62993,Q9Y6K9,P05556,Q9UBI6,P08238,P63151,P23588,P63000,Q02750,P07900,P11047,P06730,O00459,P06756,Q8N122,P28482,P07942,Q15382,P30154,P29317 21 +Glycosaminoglycan degradation 0.9762117157300012 2.408996536850783 0.0159964497695472 0.9999456788200624 0.3359254451604929 5 P15586,P54802,P16278,P06865 4 +Alzheimers disease 0.508720124816894 2.380735528549487 0.0172781117023785 0.9999754385942832 0.3435958382206551 86 P19525,P28074,P67870,P05067,P04350,P78536,Q07954,P60900,P49768,P49721,Q92542,Q02750,P28070,Q99436,Q9BUF5,O43242,P28072,O00459,P05198,P25788,P07437,Q13885,Q13564 23 +Primary focal segmental glomerulosclerosis fsgs 0.7112855306843617 2.376239630373909 0.0174901001393108 0.9999784625911676 0.3435958382206551 21 P05556,Q14108,P19022,Q14517,P11047,P06756 6 +Proteasome degradation 0.5885324494343468 2.2963699531280817 0.0216547374586641 0.99999837924589 0.3663624128913313 42 P51665,Q15008,P01889,Q99436,P28074,Q13200,P28070,O43242,P25788,O75832,P25786,P28072,P46934,P60900,P49721,P04439,P10321,P55036 18 +Splicing factor nova regulated synaptic proteins 0.7071033645365336 2.246612650502344 0.0246647929861159 0.999999751843338 0.3663624128913313 18 Q06481,Q92859 2 +Complement system in neuronal development and plasticity 0.7329715682651942 2.1999868318992446 0.0278078293065557 0.999999965243132 0.3803233243472542 14 Q08431,Q5KU26 2 +Alzheimers disease and mirna effects 0.4856615909623183 2.1787301854635976 0.0293517179709703 0.9999999867964372 0.3803233243472542 88 P19525,P28074,P67870,P05067,P04350,P78536,Q07954,P60900,P49768,P49721,Q92542,Q02750,P28070,Q99436,Q9BUF5,O43242,P28072,O00459,P05198,P25788,P07437,Q13885,Q13564 23 +Familial hyperlipidemia type 4 0.964755636245445 2.157295231188232 0.03098266834748 0.999999995258554 0.3875834423987085 4 P01130 1 +Cholesterol biosynthesis with skeletal dysplasias 0.8754056745267107 2.1524312671873664 0.0313634032922534 0.99999999626774 0.3875834423987085 6 Q16850,Q9UBM7,Q15392 3 +Statin inhibition of cholesterol production 0.8537484540705418 2.1365090555090256 0.0326379436624977 0.9999999983260957 0.3897354449110022 7 P01130,Q07954 2 +Sphingolipid metabolism in senescence 0.727947708947489 2.109099145680175 0.0349360245967818 0.9999999996067512 0.3940007218414836 13 Q13510,P16278 2 +Folate metabolism 0.7065022907593571 2.074214741307633 0.0380593717715587 0.9999999999453872 0.4214210437978046 14 P01130 1 +Ferroptosis 0.6233876764378944 2.0562276173151415 0.0397605814454826 0.9999999999814162 0.4248104228122622 26 P02786,P08195,P02792,Q96QD8 4 +Copper homeostasis 0.8471445486214253 2.044230080670555 0.0409308228338076 0.9999999999911569 0.4297736397549805 6 P05067 1 +Selenium micronutrient network 0.723601605262156 2.0270396995705378 0.0426583528323991 0.9999999999970504 0.4403209639818828 12 P01130 1 +Metapathway biotransformation phase i and ii 0.6330002772692136 1.9820208858166637 0.0474769031151325 0.9999999999998634 0.475121933011137 22 P34913,Q7LGA3,Q86UY6,Q16850 4 +Development of ureteric collection system 0.8592127020751724 1.972908261371341 0.0485060152247951 0.9999999999999292 0.475121933011137 5 O94813,Q9Y6N7 2 +Oxysterols derived from cholesterol 0.8282260463848033 1.971111662219495 0.0487111050772708 0.999999999999938 0.475121933011137 6 P34913 1 +Vitamin d receptor pathway 0.702844102403821 1.9318204466323012 0.0533816715011981 0.9999999999999968 0.475121933011137 12 P08183,P48960 2 +Head and neck squamous cell carcinoma 0.6455131840012415 1.9281895859839573 0.0538315490603751 0.9999999999999976 0.475121933011137 18 Q8N122,Q14517,P06730,O00459,Q04721,P62942 6 +Arrhythmogenic right ventricular cardiomyopathy 0.6410564973450184 1.9046896643240752 0.0568204233183122 0.9999999999999996 0.4943376828693168 18 P05556,Q14126,P19022,Q02487,P06756 5 +Proximal tubule transport 0.6996965522396792 1.8621379162997125 0.062583652712201 1.0 0.5257488445154956 11 P08183,P08195 2 +Small cell lung cancer 0.6323481632016371 1.8585953664478836 0.0630845143836131 1.0 0.5257488445154956 18 P05556,P07942,P11047,O00459,P06756 5 +Focal adhesion pi3kaktmtorsignaling pathway 0.5141229358479077 1.8423769195080644 0.0654200354678378 1.0 0.5257488445154956 47 P05556,P23588,Q8N122,Q02750,P07942,P07900,P62993,P11047,P06730,Q9Y6K9,Q9Y376,O00459,Q15382,P29317,P08238,Q96B36,P06756,P11166 18 +Familial hyperlipidemia type 2 0.9809863339275112 1.8272488159277895 0.0676623671685687 1.0 0.5257488445154956 2 P01130 1 +Aryl hydrocarbon receptor pathway wp2586 0.725616593723863 1.8013115816049756 0.0716537834068737 1.0 0.5257488445154956 9 P28482,Q02750,P07900,Q16543,P06400,O00170 6 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.7184049865094239 1.7704618402357504 0.0766502358766025 1.0 0.5403136205062528 9 P05556,Q8N122,Q13418,Q15118,P06730,Q96B36 6 +Fluoropyrimidine activity 0.6562621683991167 1.7701380855622602 0.0767041403638479 1.0 0.5403136205062528 13 Q92820 1 +Integrinmediated cell adhesion 0.5680045883168685 1.757401228971053 0.078849444000721 1.0 0.5403136205062528 27 P05556,P28482,P63000,Q02750,Q13418,P62993,P46108,O00459,Q13177,P06756 10 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.7940614488484068 1.722007496290792 0.08506816055478 1.0 0.5403136205062528 5 P61201,P06753,P22466 3 +Familial hyperlipidemia type 3 0.973551263001486 1.7055608181273278 0.0880898797256493 1.0 0.5403136205062528 3 P01130,Q07954 2 +Familial hyperlipidemia type 5 0.97316958917999 1.7041913495305092 0.088345344779251 1.0 0.5403136205062528 3 P01130 1 +Familial hyperlipidemia type 1 0.97316958917999 1.7041913495305092 0.088345344779251 1.0 0.5403136205062528 3 P01130 1 +P53 transcriptional gene network 0.6604911665574298 1.6830572289394756 0.0923640132625678 1.0 0.544266828605518 11 P04066 1 +Irinotecan pathway 0.9423648247177672 1.674408386774169 0.0940503656610038 1.0 0.544266828605518 2 O15118 1 +Genes controlling nephrogenesis 0.7135805063180252 1.6611603263414785 0.0966812512215262 1.0 0.544266828605518 8 P05556,Q13418,O94813,P11047,Q04721 5 +Notch signaling 0.7131466974132968 1.6593421289667367 0.097046870531587 1.0 0.544266828605518 8 P49768,P78536,Q92542 3 +Inflammatory response pathway 0.9385026737967924 1.6590910321902188 0.0970974500768102 1.0 0.544266828605518 2 P07942 1 +Monoamine transport 0.9292929292929304 1.6225497587189155 0.1046856879981241 1.0 0.544266828605518 2 O15127 1 +Aryl hydrocarbon receptor pathway wp2873 0.7683615819208968 1.621732387048756 0.1048606610153317 1.0 0.544266828605518 5 O00170,Q07812,P07900,Q15185 4 +Imatinib and chronic myeloid leukemia 0.8188488158268921 1.614965404237307 0.1063181870179996 1.0 0.544266828605518 4 P08183 1 +Hippomerlin signaling dysregulation 0.563383529917199 1.609322132707727 0.1075459219583405 1.0 0.544266828605518 23 P05556,P19022,P29317,P10644,P06756 5 +Tcell receptor tcr signaling pathway 0.5779258201098986 1.6050658988529003 0.1084793029948201 1.0 0.544266828605518 19 P28482,Q02750,Q9UJU6,Q06124,P62993,Q16512,P46108,Q9Y6K9,P36507,O00459,Q04206,P27361,P08670 13 +Alpha 6 beta 4 signaling pathway 0.6430746602616081 1.6025587506104473 0.1090321068799231 1.0 0.544266828605518 11 P07942,O00459,P11047 3 +Vitamin b12 metabolism 0.6970025006279451 1.59149620315782 0.111497949227767 1.0 0.5520508217862611 8 P01130 1 +Malignant pleural mesothelioma 0.452634699500926 1.5859984489291774 0.1127396614115703 1.0 0.5536972080616639 73 P05556,Q8N122,P19022,Q02487,P11166,P09429,P07942,P67870,P11047,Q14574,P29317,Q96B36,Q08722,P08195,P06756 15 +Nuclear receptors metapathway 0.4745575179396544 1.5697803795291236 0.1164662137030516 1.0 0.5541244073840504 54 P08183,Q08431,P02792,P27105,O00170,P29317,Q9H2J7,Q15043 8 +Synaptic signaling pathways associated with autism spectrum disorder 0.6319625697245168 1.5509239577109315 0.1209199082764174 1.0 0.5664632626179862 11 Q8N122,P54619,Q05086,O00459,Q15382 5 +Translation factors 0.5003526117963328 1.51124590108186 0.1307258116453475 1.0 0.5985866112181705 37 P19525,Q14240,O60841,O75821,Q13347,P60842,Q9NR50,P55010,O00303,O75153,P24534,P23588,P62495,Q04637,P63241,P06730,P26641,P55884,P05198,P49770,O15372,P20042,O75822,Q15056,P29692,Q13144 26 +Metabolic pathway of ldl hdl and tg including diseases 0.91483170285774 1.4942458617041958 0.1351113696325585 1.0 0.5986635384743854 3 P01130 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6928691144588782 1.4922606137304797 0.1356308377008619 1.0 0.5986635384743854 7 Q8N122,Q15118,O00459 3 +Inclusion body myositis 0.907875185735513 1.469166128092526 0.1417877350663849 1.0 0.5986635384743854 3 P05067,Q92542 2 +Glucocorticoid receptor pathway 0.6673359761605431 1.4659890014036043 0.142651283243377 1.0 0.5986635384743854 8 Q08431 1 +Tgfbeta signaling pathway 0.5067756009187703 1.45656014886673 0.1452378348640177 1.0 0.5986635384743854 32 P05556,P63000,Q02750,Q15118,P06493,P62993,P05067,O00459,O14964,Q13177,Q96PU5,Q96J02,Q92905 13 +Spinal cord injury 0.5429380324100024 1.4446890619568389 0.1485452436241636 1.0 0.5986635384743854 21 P63000,O94813,P17931,P06493,Q08722,P62942 6 +Nephrotic syndrome 0.5884030153760655 1.438663977802391 0.1502457500961469 1.0 0.5986635384743854 13 Q14108,O75844 2 +Vitamin d metabolism 0.8986016070487246 1.4357346376860936 0.1510778650222417 1.0 0.5986635384743854 3 P04062 1 +Complement system 0.5973560268828976 1.4337423536880771 0.1516458009131169 1.0 0.5986635384743854 12 P07942 1 +Network map of sarscov2 signaling pathway 0.5048159667249013 1.4134450668584209 0.1575249025474283 1.0 0.6086826642737531 30 Q8N122,Q08380,P60520,P06730,Q9Y6K9,Q15382,Q96B36,Q96J02 8 +Regulation of actin cytoskeleton 0.4799433443653297 1.4112196011765696 0.1581798722701273 1.0 0.6086826642737531 39 P15311,P07737,Q16512,P23528,Q96F07,P35580,Q9UBI6,P12814,Q9NSV4,Q02750,P63000,Q9Y6W5,P36507,O00459,Q13177,P28482,Q9UQB8,P46108,P46940,P26038,P27361 21 +Nanoparticlemediated activation of receptor signaling 0.686573112777274 1.4087228053343914 0.1589171488005365 1.0 0.6086826642737531 6 P05556,Q02750,P62993 3 +Orexin receptor pathway 0.5379075459826426 1.39703478695186 0.1624031104526451 1.0 0.6181468391603804 20 P01130,O00459 2 +Purine metabolism 0.665605146426848 1.3799729063709318 0.1675949870215349 1.0 0.6261677735957962 7 P00492,P07741 2 +Dna damage response only atm dependent 0.5315298054854158 1.3603959113949124 0.1737046716259223 1.0 0.6369657561755947 20 P01130,Q15118,O00459,P09429 4 +Nephrogenesis 0.8621509209744502 1.3562717562604538 0.1750127184192502 1.0 0.6369657561755947 2 Q04721 1 +Met in type 1 papillary renal cell carcinoma 0.5265863105080616 1.3494926351078675 0.1771787843554442 1.0 0.6369657561755947 21 P28482,P63000,Q02750,P62913,Q06124,P62993,Q16512,P46108,P36507,O00459,Q13177,Q92733,P27361 13 +Mapk cascade 0.6978887897710288 1.3442967265062702 0.1788524537044773 1.0 0.6369657561755947 5 Q02750,P28482,P36507,P62993 4 +Hippo signaling regulation pathways 0.5371600700462994 1.3086650569258464 0.1906478331561762 1.0 0.652272642652311 17 P19022,P29317 2 +Sterol regulatory elementbinding proteins srebp signaling 0.4859512976231864 1.300255996684887 0.1935132441873208 1.0 0.6583774620674772 31 P01130,Q8WTV0 2 +Thyroid hormones production and peripheral downstream signaling effects 0.5281970089144382 1.2909739420951607 0.1967127134193931 1.0 0.66554468040228 18 Q8N122,P62993,Q15382,Q96B36,P06756 5 +Focal adhesion 0.4632836290321724 1.2637593299273542 0.2063164228106502 1.0 0.6718038476250511 38 P05556,P28482,P63000,Q02750,Q13418,P07942,P62993,Q16512,P11047,P46108,O00459,Q13177,P06756 13 +Hair follicle development cytodifferentiation part 3 of 3 0.6772200770804349 1.2626509170136666 0.2067146607043311 1.0 0.6718038476250511 5 Q02487,P78536 2 +Interferon type i signaling pathways 0.5272137282190479 1.254412101826868 0.2096922561108836 1.0 0.6718038476250511 17 P23588,Q8N122,Q53EL6,P06730,O00459 5 +Hepatocyte growth factor receptor signaling 0.56022579603788 1.2540754050310463 0.2098145990115312 1.0 0.6718038476250511 12 P05556,P28482,Q02750,Q06124,P46108,P62993,Q16512,P36507,P27361 9 +Ras signaling 0.4870276899554418 1.24348608845087 0.213688764212502 1.0 0.6718038476250511 27 P28482,P63000,Q02750,Q9UBI6,Q06124,P62993,Q16512,Q9Y6K9,P36507,O00459,P29317,Q13177,Q04206,P27361,P11233 15 +Base excision repair 0.5107773011968286 1.2405902525761534 0.2147571546247539 1.0 0.6718038476250511 20 P09429,P49005,Q9NRF9,P29372,P13051 5 +Nrp1triggered signaling pathways in pancreatic cancer 0.5572396188740844 1.2395718623118226 0.2151337934268282 1.0 0.6718038476250511 12 P28482,P63000,Q02750,Q9UIW2,P36507,Q04206,O14786 7 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.5332723661135724 1.2328193594428902 0.217643166846011 1.0 0.6718038476250511 15 Q12959,Q02750,Q15118,P27361,P62993,Q16512,P36507,Q9Y6K9,O95433 9 +Bladder cancer 0.606775610653052 1.2075559767689426 0.2272181013652505 1.0 0.6718038476250511 8 P28482,Q02750,P06400,O00459,P42771 5 +Kallmann syndrome 0.7098692033293644 1.2008521926044948 0.2298085418148761 1.0 0.6718038476250511 4 P62993,P28482,Q06124 3 +Brainderived neurotrophic factor bdnf signaling pathway 0.4340441864271762 1.1986498980886064 0.2306641071904258 1.0 0.6718038476250511 46 Q99523,P19022,P13591,P78536,P10586,P84095,P67809,Q9Y6K9,O00459,P05198 10 +Sarscov2 and covid19 pathway 0.707836859364736 1.1931514476756633 0.2328100656545335 1.0 0.6718038476250511 4 Q8WTV0 1 +Rac1pak1p38mmp2 pathway 0.5148403556148443 1.1867439771002095 0.2353286227764521 1.0 0.6718038476250511 17 P05556,P28482,P63000,P46108,P62993,P43246,Q9Y6K9,Q16512,Q07812,Q04206,P16949 11 +Ketogenesis and ketolysis 0.6274536181534277 1.1695279107655894 0.2421910028069316 1.0 0.6718038476250511 6 O43772 1 +Notch signaling pathway 0.5109179440958572 1.1652607054411332 0.2439134797008315 1.0 0.6718038476250511 17 P78536,Q92542,O00459,Q04721,P49768 5 +Canonical and noncanonical notch signaling 0.8224367690018013 1.1624071660604005 0.2450701138183051 1.0 0.6718038476250511 3 P49768 1 +Sudden infant death syndrome sids susceptibility pathways 0.4682656662734944 1.1576278066279526 0.2470159566575591 1.0 0.6718038476250511 29 P42892,P67809,P10644 3 +Serotonin receptor 2 and elksrfgata4 signaling 0.6976813317479136 1.154724185881798 0.2482033919796933 1.0 0.6718038476250511 4 Q02750,P28482,P36507 3 +Serotonin receptor 467 and nr3c signaling 0.6976813317479136 1.154724185881798 0.2482033919796933 1.0 0.6718038476250511 4 Q02750,P28482,P36507 3 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.6976813317479105 1.154724185881785 0.2482033919796986 1.0 0.6718038476250511 4 P19022,P28482,P08670 3 +Supression of hmgb1 mediated inflammation by thbd 0.6798653983245662 1.0875771876965703 0.2767818060290929 1.0 0.7248543322398626 4 P09429 1 +Nucleotidebinding oligomerization domain nod pathway 0.5293552761569168 1.067654435293749 0.2856764190138126 1.0 0.7403274007634548 11 Q13685,P63000,Q7L5N1,P07900,Q9Y6K9 5 +Kisspeptinkisspeptin receptor system in the ovary 0.5996757312871382 1.0575125964007204 0.2902777088740991 1.0 0.7451892826581339 6 Q02750,Q15118,P28482,P36507 4 +Hijack of ubiquitination by sarscov2 0.6245259909852234 1.0554416168734606 0.2912233978204201 1.0 0.7451892826581339 5 Q8TBC4,Q13564,Q13617 3 +Hair follicle development organogenesis part 2 of 3 0.6703348055796288 1.0518335874794331 0.2928759061904689 1.0 0.7462821207949604 4 P13591 1 +Sphingolipid pathway 0.5492973346959895 1.0291435420790251 0.303412227836461 1.0 0.7541961091934889 9 Q13510 1 +Pathogenic escherichia coli infection 0.4706818261507587 1.0202969052249995 0.3075876706361493 1.0 0.755750514981073 21 P05556,P04350,Q14247,P63104,P15311,Q9BUF5,P07437,Q13885,O15143,P19338 10 +Ciliopathies 0.4682048009909573 1.020014641995179 0.3077215166275282 1.0 0.755750514981073 22 O43924,Q10713,Q9ULC3 3 +15q112 copy number variation syndrome 0.6605231866825128 1.0151938929080473 0.3100134111717858 1.0 0.755750514981073 4 Q9BSJ2,Q06787,Q96CW5 3 +Tcell activation sarscov2 0.4816125896082365 1.0045418715480472 0.3151174994640611 1.0 0.755750514981073 17 Q8N122,P28482,Q02750,P62993,P36507,P42771,Q15382,Q9Y6K9,Q07812,Q04206 10 +Nrf2 pathway 0.4516546052735338 0.99048753593558 0.3219358783736579 1.0 0.758962229936051 26 P02792,Q9H2J7,Q15043,P29317 4 +Disruption of postsynaptic signaling by cnv 0.5392188644038127 0.9847700893688248 0.3247370158588065 1.0 0.758962229936051 9 Q14168,Q12959,Q06787 3 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.5695755907460733 0.9836868099574132 0.3252695271154504 1.0 0.758962229936051 7 P28482,Q96KB5,Q02750,P06730,P36507 5 +Target of rapamycin tor signaling 0.5031614906585622 0.9768535599732744 0.3286416556362601 1.0 0.7639036957346658 12 Q8N122,P54619,Q96B36,Q15382,P62942 5 +Fragile x syndrome 0.4040321285509856 0.951141800953369 0.3415323975416311 1.0 0.7712337146989036 46 Q8N122,P09496,Q15118,Q06787,Q14118,P62993,P06730,P05067,Q96B36,P10644 10 +Endochondral ossification 0.5589850919691073 0.9404652662142028 0.3469789580097107 1.0 0.7712337146989036 7 Q96QD8 1 +Endochondral ossification with skeletal dysplasias 0.5589850919691073 0.9404652662142028 0.3469789580097107 1.0 0.7712337146989036 7 Q96QD8 1 +Erbb signaling pathway 0.4645202824911006 0.9344411143607418 0.3500763978750023 1.0 0.7712337146989036 18 P28482,Q02750,P46108,P62993,Q16512,P36507,O00459,Q13177,P27361 9 +Cannabinoid receptor signaling 0.5684025737477939 0.9325704298867716 0.3510418068183412 1.0 0.7712337146989036 6 P10644,Q8NCG7 2 +Ebsteinbarr virus lmp1 signaling 0.5667168154991662 0.9258881134475028 0.3545041292033435 1.0 0.7712337146989036 6 P28482,Q9Y6K9,P07900 3 +Melanoma 0.4742457657080259 0.922916118323355 0.3560509201753075 1.0 0.7712337146989036 15 P28482,P63000,Q02750,P06400,P62993,Q16512,P36507,O00459,P42771,Q07812 10 +Erk pathway in huntingtons disease 0.7474747474747516 0.912993639821517 0.3612458865965999 1.0 0.7719254208327346 2 P28482 1 +Prostaglandin and leukotriene metabolism in senescence 0.7488855869242208 0.9051808858167228 0.3653695663442273 1.0 0.775568715611275 3 P09960,P63096 2 +Regulatory circuits of the stat3 signaling pathway 0.5339202644952606 0.897700666046654 0.3693451542848582 1.0 0.775568715611275 8 Q8N122,P16949 2 +Il6 signaling pathway 0.485202059376385 0.8901818911946738 0.3733682266290954 1.0 0.7761428397150615 12 P28482,P63000,Q02750,Q06124,P62993,P36507,O00459 7 +Joubert syndrome 0.4516923919360553 0.887420243729179 0.3748526884869423 1.0 0.7764805690086661 19 O43924,Q10713,Q15154,P41208 4 +Hypertrophy model 0.7346999405822978 0.8657655484873302 0.3866187456042094 1.0 0.7913788658647697 2 P06730 1 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4377128658755697 0.8651051863685612 0.3869810583598054 1.0 0.7913788658647697 24 Q16850,Q14739,Q9UBM7,Q15392 4 +Pilocytic astrocytoma 0.7296494355317934 0.8472768927306348 0.3968408031953316 1.0 0.8060076257328421 2 P62993 1 +Hepatitis b infection 0.4316250715051002 0.8436195243819177 0.3988820504290187 1.0 0.8070404276122006 25 P28482,P63104,Q02750,P62993,P27348,Q15904,Q9Y6K9,O00459,Q07812,Q04206 10 +Autophagy 0.4904454455108039 0.8260462471101797 0.4087778579584602 1.0 0.8162154606449255 10 Q8N122,Q96B36 2 +Praderwilli and angelman syndrome 0.5289140756301813 0.8191449452674268 0.4127037214109199 1.0 0.8197435493450986 7 Q05086,P42771,Q15154 3 +Mirna regulation of prostate cancer signaling pathways 0.4877999490766181 0.8142360487136734 0.4155097377684078 1.0 0.8197435493450986 10 Q02750,Q8NCF5,Q9Y6K9,P62993 4 +Proteoglycan biosynthesis 0.604192336089423 0.8093213797046204 0.4183303116603927 1.0 0.8218166445199326 4 Q9NX62 1 +Glioblastoma signaling pathways 0.4446736405415001 0.7847530139849845 0.4325983934039006 1.0 0.8417010274216468 16 P28482,Q02750,P06400,P62993,P36507,O00459,P42771,P52701 8 +Ethanol metabolism production of ros by cyp2e1 0.7094474153297736 0.7744860152106138 0.4386434350896933 1.0 0.846986260843624 2 Q02750 1 +Resistin as a regulator of inflammation 0.5226904829126441 0.7542618241064005 0.4506920208047233 1.0 0.8550512170407368 6 P28482,Q9Y6K9,Q04206 3 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.4404768261675537 0.7476013527217096 0.4547006485578513 1.0 0.8573148451137196 15 P55209,O75844 2 +Angiotensin ii receptor type 1 pathway 0.6986014556174549 0.7377218145008031 0.4606835131469939 1.0 0.8623524271677969 3 P28482 1 +Neovascularisation processes 0.6974739970282328 0.7340804586888845 0.4628997025607408 1.0 0.8623524271677969 3 Q04206,P28482 2 +Mapk pathway in congenital thyroid cancer 0.6974739970282327 0.7340804586888837 0.4628997025607413 1.0 0.8623524271677969 3 Q02750,P36507 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4427600292853416 0.715679886858216 0.4741890329019163 1.0 0.8665828037668527 13 O15372,O75821,P20042,O75822,Q13347,P55010,P55884,P05198 8 +Egfr tyrosine kinase inhibitor resistance 0.4340600434454111 0.7147221950825798 0.4747807202416674 1.0 0.8665828037668527 15 Q02750,P62993,P06730,O00459,Q07812 5 +Il9 signaling pathway 0.4896324302519154 0.7147008122452595 0.4747939357496411 1.0 0.8665828037668527 8 P28482,Q02750,P62993,P36507,O00459 5 +Prolactin signaling pathway 0.4168405990436498 0.712640080061791 0.4760685035693281 1.0 0.8665828037668527 22 P05556,P28482,P63104,P63000,Q02750,Q06124,P62993,Q16512,P36507,O00459,Q04206 11 +Purine metabolism and related disorders 0.4460667461263057 0.7044199803593472 0.4811712666916623 1.0 0.8669624302225514 12 P30520,Q9BY32,P07741,P22102,P31153,P00491,P00492,Q06203,P31939,P30566,P22234 11 +Cellular proteostasis 0.6869795814859763 0.7004681545542407 0.4836349861550191 1.0 0.8688309928271583 3 Q99471 1 +Physicochemical features and toxicityassociated pathways 0.4302388022098761 0.695232085410893 0.4869098677678494 1.0 0.8721414984430008 15 P35080,P28482,Q02750,P62993,P07737,P07197 6 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.4592300375541569 0.6884048138030163 0.4911978932788563 1.0 0.8771964815130111 10 P05556,Q16512,Q13177 3 +Neurodegeneration with brain iron accumulation nbia subtypes pathway 0.4277563709651429 0.6826094834147509 0.4948536399793912 1.0 0.8786176873103477 15 Q8N122,Q96B36,Q15382,P02792 4 +Tolllike receptor signaling pathway 0.4299658232864369 0.6542866704448467 0.5129271319716329 1.0 0.8938574619367246 13 P28482,P63000,Q02750,P36507,O00459,Q9Y6K9,Q04206 7 +Cholesterol biosynthesis pathway 0.423756825735714 0.6518850732329959 0.5144753149209238 1.0 0.8938574619367246 14 Q16850,Q9UBM7 2 +Tolllike receptor signaling related to myd88 0.5581931405593364 0.6500365717507577 0.5156685985632363 1.0 0.8938574619367246 4 P28482,Q9Y6K9 2 +Chemokine signaling pathway 0.3998777708639308 0.6324900988411902 0.5270666762545444 1.0 0.9041791713775142 24 P28482,P63000,Q02750,P63096,Q9UBI6,P62993,Q16512,P46108,Q9Y6K9,O00459 10 +16p112 distal deletion syndrome 0.4564263030875589 0.6301118382686454 0.5286214148376938 1.0 0.9042989933599874 9 P62993,Q9H2V7 2 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.4770901126207258 0.6179441766533168 0.5366121370791543 1.0 0.915397175017381 7 Q9UPY5,Q9Y6K9 2 +Estrogen signaling pathway 0.4835388620852917 0.6084966668003527 0.542858115994862 1.0 0.9228513822342292 6 Q02750,Q9Y6K9 2 +Epo receptor signaling 0.4533882213329201 0.5715968068811118 0.5675951592063544 1.0 0.933956311816447 8 P28482,Q02750,Q15118,P62993,P36507 5 +Modulators of tcr signaling and t cell activation 0.4109157477163013 0.5647419748364247 0.5722492794666292 1.0 0.933956311816447 13 Q9Y6K9,O00459,O96000 3 +Parkinubiquitin proteasomal system pathway 0.3733303118570584 0.5563179106292658 0.577993545283022 1.0 0.933956311816447 35 Q13200,P54652,O75832,Q9BVA1,Q15008,P04350,Q99460,P68036,Q9BUF5,O43242,Q9UNE7,P55036,P51665,P62333,Q9UNM6,Q0VDF9,P34932,P07437,Q13885,O00231 20 +Nonsmall cell lung cancer 0.3952652035236277 0.5537716251417533 0.5797351496508645 1.0 0.9340177411041706 18 P28482,Q02750,Q15118,P62993,O00459,P42771,Q07812,Q9HC35 8 +Oxidation by cytochrome p450 0.4674698315558155 0.551352558665447 0.5813920154707457 1.0 0.9342156660202748 6 Q16850 1 +Ectoderm differentiation 0.3870836308538016 0.5461840020436773 0.5849394618783288 1.0 0.93744245337869 23 O00560,P26583,P16278 3 +Il7 signaling pathway 0.443084319049625 0.5324817160830165 0.5943924019406421 1.0 0.947604640790186 8 Q02750,P28482,P36507,O00459 4 +Translation inhibitors in chronically activated pdgfra cells 0.3802297617025063 0.4881036862480989 0.6254764001832265 1.0 0.9762277041996652 19 P23588,Q8N122,Q53EL6,Q15118,P06730,O00459 6 +Pancreatic adenocarcinoma pathway 0.3738300192998741 0.4766022926948697 0.6336453505075361 1.0 0.9823564179255578 24 Q13177,P28482,P63000,Q02750,P06400,Q16512,Q9Y6K9,P42771,O00459,Q07812,P11233 11 +Endometrial cancer 0.3914453019660919 0.4761964376370367 0.6339344371834881 1.0 0.9823564179255578 13 Q13418,Q02750,P62993,O00459,Q07812 5 +Transcriptional activation by nrf2 in response to phytochemicals 0.4408090422367581 0.4609974313491523 0.6448004479823908 1.0 0.9891271355699648 6 Q9UPY5,P09601,Q13155,P48506,P48507 5 +Mirna biogenesis 0.4904875148632469 0.4399427191264608 0.6599785946487844 1.0 0.9990835718225328 4 P62826,Q9HAV4,Q9UPY3 3 +Transsulfuration pathway 0.42517108003571 0.4334303959929285 0.6647021222385598 1.0 0.9990835718225328 7 Q9NZL9,Q99707,P17174,P23526,P48507,P26358 6 +Il1 signaling pathway 0.3802690297352585 0.4270584201120563 0.6693367771815983 1.0 0.9990835718225328 13 P28482,P61088,Q02750,Q06124,P36507,O00459,Q9Y6K9,Q04206 8 +Vasopressinregulated water reabsorption 0.3700189832897348 0.4224356411281998 0.6727070676514391 1.0 0.9994172973938285 18 Q96FJ2,O43237,P52565,Q9UJW0,Q13561,Q14203,Q12846,Q13409 8 +Influence of laminopathies on wnt signaling 0.4017778452475213 0.4169529858464563 0.6767127962298334 1.0 1.0 9 O75844 1 +Pentose phosphate metabolism 0.4391911983348277 0.3992960708037375 0.6896750619446628 1.0 1.0 5 P37837,O95336,P29401,P52209 4 +Burn wound healing 0.4057187487337683 0.3984016427518163 0.6903341471888005 1.0 1.0 8 P07737,P09429,P08670 3 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.4207034643189517 0.3972326542203218 0.6911959043440379 1.0 1.0 6 Q02750,P28482,P36507 3 +Genes related to primary cilium development based on crispr 0.372243417543492 0.3926580564021956 0.6945720535803477 1.0 1.0 13 Q9Y366,Q10713,Q96J42,Q9ULC3 4 +Tnfalpha signaling pathway 0.3599260869389045 0.3833033086355314 0.7014948863239545 1.0 1.0 21 P28482,Q9NR28,P63000,Q6GQQ9,Q13200,P06737,P07900,P62993,Q9Y6K9,Q07812 10 +Methionine metabolism leading to sulfur amino acids and related disorders 0.4678953626634841 0.3787449843039644 0.7048772449755087 1.0 1.0 4 Q99707,P55263,P23526 3 +Cardiac hypertrophic response 0.3736825767540768 0.3758443642450615 0.7070326038453647 1.0 1.0 11 P28482,P63000,Q02750,Q9Y6K9,P36507 5 +Gpr40 pathway 0.5796197266785603 0.3740951125658272 0.7083335547602285 1.0 1.0 2 P19174 1 +Pdgfrbeta pathway 0.3977337718624546 0.3716127399892754 0.7101812022228879 1.0 1.0 8 P62993,P19525 2 +Striated muscle contraction pathway 0.4288753836524481 0.370175924283423 0.7112514140733945 1.0 1.0 5 P06753,O43707,P67936 3 +Ciliary landscape 0.3288580609530854 0.363646906982278 0.7161216946998374 1.0 1.0 108 P27105,P06280,P10619,Q86VI3,P16278,Q9H9Q2 6 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.5615076680394678 0.3532014644439377 0.7239374100823679 1.0 1.0 3 Q9Y6K9 1 +Il2 signaling pathway 0.3635318843223081 0.337516957698133 0.7357272309529579 1.0 1.0 11 P28482,Q02750,Q06124,P62993,P36507,P27361 6 +Tp53 network 0.5528581554363385 0.33408365050967 0.738316436994368 1.0 1.0 3 Q07812 1 +Microglia pathogen phagocytosis pathway 0.4136024351425155 0.3293309900530298 0.7419055227072067 1.0 1.0 5 O15143,O00459 2 +Hostpathogen interaction of human coronaviruses interferon induction 0.3908208440799451 0.3107910185750869 0.7559594979465505 1.0 1.0 6 Q9Y6K9 1 +Neural crest differentiation 0.367987531011364 0.300450283504579 0.7638337135468698 1.0 1.0 9 P05556,P19022 2 +Nitric oxide metabolism in cystic fibrosis 0.4341638151497272 0.2977257354334839 0.7659124996434032 1.0 1.0 4 O60678 1 +Complement and coagulation cascades 0.5407011289364348 0.2864953905396595 0.7744987234021266 1.0 1.0 2 P49257 1 +Intraflagellar transport proteins binding to dynein 0.3683917960327758 0.2800010203991655 0.7794767220254366 1.0 1.0 8 Q9BW83,Q96FJ2,O43237,Q9Y6G9,Q13409 5 +Neural crest cell migration during development 0.3775224328206288 0.2759461288583101 0.7825894431437674 1.0 1.0 6 Q13177,P63000 2 +Serotonin htr1 group and fos pathway 0.3658351510173723 0.2725734341254736 0.7851811354022269 1.0 1.0 8 Q02750,P28482,P36507,P63096 4 +Fibrin complement receptor 3 signaling pathway 0.5176607283114181 0.2641910906601526 0.7916326758822032 1.0 1.0 3 Q9Y6K9 1 +Canonical nfkb pathway 0.5176607283114181 0.2641910906601526 0.7916326758822032 1.0 1.0 3 Q9Y6K9 1 +Altered glycosylation of muc1 in tumor microenvironment 0.5176607283114181 0.2641910906601526 0.7916326758822032 1.0 1.0 3 Q9Y6K9 1 +Familial partial lipodystrophy fpld 0.3716619254622172 0.2613568442533632 0.7938173339834607 1.0 1.0 6 O75844 1 +Nad metabolism 0.5246583481877723 0.2557595879314474 0.7981364803778828 1.0 1.0 2 P43490 1 +Pentose phosphate pathway in senescent cells 0.3826940231935864 0.2557037058714223 0.7981796334110443 1.0 1.0 5 P37837,P11413,O95336,P29401 4 +Wnt signaling pathway 0.3391899940440701 0.2308061883006285 0.8174653734599899 1.0 1.0 10 P28482,P63000,Q9BTU6,P17252,P49841,P49840,P42345,Q13363,P35222 9 +Embryonic stem cell pluripotency pathways 0.3302182350664411 0.2226698788668333 0.8237924459895911 1.0 1.0 11 P28482,Q02750,Q06124,P62993,O00459 5 +Exrna mechanism of action and biogenesis 0.490341753343241 0.2190620788600596 0.8266016899989357 1.0 1.0 3 Q9HAV4,Q9UPY3 2 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3446428571428593 0.214782659212564 0.8299367733341572 1.0 1.0 8 Q96JM3,P28482,Q13555,Q15648,P27361,P17252,P42224 7 +Il4 signaling pathway 0.3276544565305924 0.2146084292818944 0.830072621444419 1.0 1.0 11 P28482,Q06124,P62993,O00459,Q04206 5 +Camkk2 pathway 0.3273394826230014 0.2142707694780825 0.830335911253973 1.0 1.0 12 Q8N122,Q9Y3D6,P28482,O00429,P63000 5 +Follicle stimulating hormone fsh signaling pathway 0.3457304373698429 0.2073748324623645 0.8357171361665279 1.0 1.0 7 P28482,P17612,Q15382,P62753,P27361,P17252 6 +Progeriaassociated lipodystrophy 0.3348137143256768 0.201753404317581 0.8401095103466407 1.0 1.0 9 O75844 1 +Ccl18 signaling pathway 0.3223897031194346 0.1984331660449629 0.8427061705814378 1.0 1.0 11 P19022 1 +Hepatitis c and hepatocellular carcinoma 0.3375823853910212 0.1970971721148817 0.8437514963494861 1.0 1.0 8 Q06124,Q14247,P62993,P63000 4 +T cell receptor and costimulatory signaling 0.338887235941691 0.1920660668264687 0.8476904547717208 1.0 1.0 7 Q15118,Q08209,P49841,P49840,P19174,P17252 6 +Gastrin signaling pathway 0.3204608403384492 0.1908470158025438 0.8486454523168216 1.0 1.0 27 P05556,P28482,P63000,Q02750,P62993,Q16512,P46108,P42771,O00459,Q04206 10 +Folatealcohol and cancer pathway hypotheses 0.4812834224599071 0.188745043578462 0.8502926463622729 1.0 1.0 2 Q99707 1 +Hostpathogen interaction of human coronaviruses autophagy 0.3455248290217168 0.1846167820608353 0.8535296220322879 1.0 1.0 5 Q9NT62,O95352,Q99570,O75143 4 +Dual hijack model of vif in hiv infection 0.4528974739970299 0.1702946641240885 0.8647784073842786 1.0 1.0 3 Q15369,Q93034 2 +Microtubule cytoskeleton regulation 0.3152488393228187 0.1672027788304503 0.8672104980096305 1.0 1.0 18 Q15691,P63000,P06493,Q16512,P16949 5 +Acute viral myocarditis 0.3128398620162732 0.1572606144275973 0.8750394591094603 1.0 1.0 18 P78310,Q14118,Q07812,Q13418 4 +Sulfation biotransformation reaction 0.438930163447253 0.1558450716476221 0.8761551426045802 1.0 1.0 3 O43252,P00390 2 +Map3k1 role in promoting and blocking gonadal determination 0.3448275862068916 0.1515759468644638 0.8795214057930667 1.0 1.0 4 P28482,Q13464,P49841 3 +Hippoyap signaling pathway 0.3403686087990417 0.146920879441652 0.8831944713489632 1.0 1.0 4 P27348,O95819,Q13188 3 +Overview of interferonsmediated signaling pathway 0.440285204991102 0.1459371380340228 0.8839710135166972 1.0 1.0 2 P42224 1 +Relationship between inflammation cox2 and egfr 0.4276374442793481 0.1455636124272489 0.8842658950273692 1.0 1.0 3 P28482,P27361 2 +Rala downstream regulated genes 0.3132017363737629 0.1436269363312786 0.8857950690706915 1.0 1.0 6 P11233 1 +Type 2 papillary renal cell carcinoma 0.3064561595683798 0.1320549020253655 0.8949408664035368 1.0 1.0 9 Q92733,P11166 2 +Il17 signaling pathway 0.3065290613127001 0.1298269618348474 0.8967033309807828 1.0 1.0 7 P28482,Q9Y6K9,Q04206 3 +Hostpathogen interaction of human coronaviruses apoptosis 0.3988112927191698 0.1245650989934575 0.9008678601045867 1.0 1.0 3 Q07812,Q07820 2 +Chromosomal and microsatellite instability in colorectal cancer 0.3010633792376084 0.1242806493745657 0.9010930680708058 1.0 1.0 15 P28482,P63000,Q02750,P43246,Q07812,P11233 6 +Hypothesized pathways in pathogenesis of cardiovascular disease 0.3836552748885607 0.1162438966109894 0.9074592480753358 1.0 1.0 3 P28482,P27361 2 +Methionine de novo and salvage pathway 0.2972329663790575 0.115080808273172 0.908381071607398 1.0 1.0 7 Q9NZL9,Q99707,P23526,P31153,P19623,Q13126 6 +Heart development 0.3513752261709243 0.1036722595453519 0.91742944167818 1.0 1.0 3 P28482 1 +Photodynamic therapyinduced nfkb survival signaling 0.3440285204991168 0.1035413906717356 0.9175333010008352 1.0 1.0 2 Q04206 1 +Purinergic signaling 0.2760384622278641 0.1035248328713607 0.9175464415973288 1.0 1.0 5 P63096 1 +Nrf2are regulation 0.289755807027987 0.102720075870669 0.9181851396870732 1.0 1.0 10 P09601,Q9UPY5,Q13155,P48506,P49841,Q96HS1,P48507,P17252,Q13618 9 +Insulin signaling in adipocytes diabetic condition 0.3453194650817256 0.1019723245243779 0.918778642379118 1.0 1.0 3 P62753,O60343 2 +Insulin signaling in adipocytes normal condition 0.3453194650817256 0.1019723245243779 0.918778642379118 1.0 1.0 3 P62753,O60343 2 +Transcription cofactors ski and skil protein partners 0.2655367231638494 0.0965033937341495 0.9231207786982418 1.0 1.0 5 O14744,P51608,Q13188,Q13547 4 +Interleukin1 il1 structural pathway 0.2826410831079154 0.0849259289422924 0.9323202779352782 1.0 1.0 9 P28482,Q02750,P06730,P36507,Q04206 5 +Osteoblast differentiation and related diseases 0.2719100335829179 0.068170895574453 0.9456495950251728 1.0 1.0 10 O00459 1 +Photodynamic therapyinduced unfolded protein response 0.2711816409410923 0.0668956877356928 0.9466647460387584 1.0 1.0 10 O43776,P23381,P05198 3 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.2607146903398931 0.0594511777888541 0.952592751130462 1.0 1.0 8 P28482,Q8WUM4,P27361,O14964 4 +P38 mapk signaling pathway 0.257378841666565 0.055732280259381 0.9555550835295056 1.0 1.0 8 P62993,P04792 2 +Il3 signaling pathway 0.2733341713253622 0.0515317423968527 0.9589018086695216 1.0 1.0 14 P28482,Q02750,Q06124,P62993,P27348,O00459,P27361 7 +Vegfavegfr2 signaling pathway 0.3474892942479209 0.0512369918994582 0.9591366752696836 1.0 1.0 179 Q96SB4,O14773,Q96KB5,P30825,Q9NYL9,P15311,O00560,Q16527,P47756,P07737,Q16512,P62993,P55209,P19338,Q15650,P05556,P23528,P35579,P04792,O00299,Q14157,Q12800,O14964,O15355,P06753,Q96B36,P54920,Q01844,Q9H299,P63000,Q02750,Q9NZB2,P07900,P06730,O00459,Q13177,Q96CT7,P42566,Q96J02,P55036,P06756,P05198,P28482,Q9Y678,O43852,O15372,P09429,P00491,O75347,P46108,P35613,P29317,Q01105,Q8WU90 54 +Endoderm differentiation 0.2944180691929842 0.048172791067981 0.9615785345865616 1.0 1.0 30 P05067 1 +Myometrial relaxation and contraction pathways 0.2816514682975197 0.0476439552738795 0.962000000542422 1.0 1.0 17 P62258,Q05682,P63104,Q9UBI6,P27348,P10644 6 +Measles virus infection 0.2918634977514483 0.0433328606744399 0.9654361967850889 1.0 1.0 26 P19525,P67870,Q9Y6K9,O00459,P05198 5 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..58d801c5f9a31c740426203db63681da647114bb --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpcrs class b secretinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADGRE5", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFIP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARL2", "ARL3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG3", "ATG7", "ATIC", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AURKA", "B3GALT6", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAP1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCKDHA", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRD1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP8", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2A", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CEP290", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLK2", "CLPTM1L", "CLTA", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCK", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMD", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPAGT1", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAT1", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GAL", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GCLC", "GCLM", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID4", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2H1", "GTF2I", "GTPBP4", "GTSE1", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HELLS", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "IKBKG", "ILF2", "ILK", "IMPAD1", "IMPDH2", "INF2", "INPPL1", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIRREL1", "KLC1", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LYN", "LYRM7", "LZTFL1", "MACF1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED14", "MFAP1", "MFGE8", "MFN2", "MGA", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFB", "NELFCD", "NEO1", "NET1", "NF2", "NFATC2IP", "NIPBL", "NKRF", "NLRX1", "NME1", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NR2F2", "NRP1", "NSDHL", "NSF", "NT5C3A", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "OTUD7B", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBK", "PBRM1", "PBXIP1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKN1", "PKN2", "PKP2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP4", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RIF1", "RING1", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF40", "RNMT", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLIT2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR3", "SSR4", "STAG1", "STAG2", "STAM2", "STAT1", "STAT3", "STIP1", "STK3", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TALDO1", "TAP1", "TARDBP", "TBC1D1", "TBC1D10A", "TBC1D4", "TBCA", "TBL2", "TCF20", "TCP1", "TDP2", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMEM165", "TMEM38B", "TMEM43", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRMT2A", "TRRAP", "TSG101", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNG", "UPF1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR26", "WDR5", "WFS1", "WIPI2", "WNK1", "XAB2", "XPC", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZBTB33", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["AAMP", "ABCB1", "ACTN1", "ACTN4", "ADAM17", "ADGRE5", "ADK", "ADSL", "ADSS", "AHCY", "AHSA1", "AIMP2", "AIP", "AKT1S1", "APLP2", "APP", "APRT", "ARHGDIA", "ARPC1B", "ASAH1", "ATG13", "ATG3", "ATG7", "ATIC", "ATP6AP1", "BAIAP2", "BAX", "BSG", "CAB39", "CALD1", "CALU", "CAMK2G", "CAPZB", "CCDC124", "CD47", "CDC37", "CDH2", "CDK1", "CDKN2A", "CETN2", "CFL1", "CHAMP1", "CLIC1", "CLTA", "CLUH", "COLEC12", "COPG1", "COPS2", "COPS5", "COPS6", "COPS7B", "CRK", "CSNK2B", "CSRP2", "CTBP1", "CTNNB1", "CTSA", "CTTN", "CUL2", "CUL3", "CUL5", "CXADR", "CYFIP2", "CYP51A1", "DAG1", "DAGLB", "DBNL", "DCTN1", "DCTN2", "DCTN4", "DHCR24", "DHCR7", "DIABLO", "DIAPH3", "DICER1", "DLG1", "DNM1L", "DNMT1", "DSC2", "DSC3", "DSG2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL2", "ECE1", "EEF1B2", "EEF1D", "EEF1G", "EIF2AK2", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOC", "EML4", "EPHA2", "EPHX2", "EPS15", "ETF1", "EWSR1", "EZR", "FAM120A", "FAT1", "FIS1", "FKBP1A", "FMR1", "FTL", "FUCA1", "G6PD", "GABARAPL2", "GAL", "GART", "GBA", "GCLC", "GCLM", "GGH", "GLA", "GLB1", "GM2A", "GNAI1", "GNG12", "GNS", "GOT1", "GRB2", "GSK3A", "GSK3B", "GSR", "HDAC1", "HEXA", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMOX1", "HPRT1", "HS2ST1", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA2", "HSPA4", "HSPB1", "IFT27", "IFT52", "IKBKG", "ILK", "IMPAD1", "IQGAP1", "IQGAP3", "ITCH", "ITGAV", "ITGB1", "ITPA", "LAMB1", "LAMC1", "LBR", "LDLR", "LGALS3", "LGALS3BP", "LMAN1", "LRP1", "LTA4H", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAT2A", "MAT2B", "MCL1", "MECP2", "MED1", "MFGE8", "MPG", "MPP2", "MSH2", "MSH6", "MSN", "MTAP", "MTOR", "MTR", "MYH10", "MYH9", "NAA40", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NCAM1", "NCL", "NCSTN", "NDUFB10", "NEDD4", "NEDD4L", "NEFM", "NEO1", "NFATC2IP", "NOTCH2", "NPC1", "NPC2", "NRP1", "OTUD7B", "PAICS", "PAK2", "PAPSS1", "PBK", "PCM1", "PDCD4", "PDCD6IP", "PDE6D", "PDK1", "PFDN5", "PFN1", "PFN2", "PGAM5", "PGD", "PGLS", "PI4K2A", "PIK3R2", "PIK3R4", "PKN1", "PLCG1", "PLXNA1", "PMPCA", "PNP", "POLD2", "POLE3", "PPAT", "PPM1G", "PPP2R1B", "PPP2R2A", "PPP3CA", "PRCC", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRMT3", "PRMT5", "PSEN1", "PSMA1", "PSMA3", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PTGES3", "PTPN11", "PTPRF", "PYGL", "RAB23", "RAC1", "RALA", "RAN", "RB1", "RELA", "RHEB", "RHOG", "ROBO1", "ROCK1", "RPL11", "RPS6", "RPTOR", "SCAMP2", "SCARB1", "SCARB2", "SDCBP", "SET", "SH3BGRL3", "SLC25A20", "SLC2A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC6A15", "SLC7A1", "SLC7A11", "SLIT2", "SORT1", "SPNS1", "SRM", "SRPK1", "STAT1", "STK3", "STMN1", "STOM", "STUB1", "STX4", "TALDO1", "TBC1D4", "TBCA", "TFCP2", "TFRC", "TKT", "TMOD3", "TPM3", "TPM4", "TPP1", "TRIP4", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TXNDC15", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE3A", "UNG", "VIM", "WARS", "WASF2", "XPO5", "YBX1", "YWHAE", "YWHAQ", "YWHAZ", "ZC3H15", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json 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b/opencell_localization/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab3f44339297f0755652866e7c8704ee3baa04416812bb30b89424cc47ddad47 +size 143645 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..26f48825cb4eeb8b318f0f64f4a59bc6f16fadaf --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:531f543a994f522dee96470c6a96a35ec4b41be59e57bcf0ac1a288f0d1871b2 +size 76222 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..afc64c3b48008434a3b44d1d9b1f7bfc908ebef8 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 98.82352941176471 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..96bdcd76b46ca5088e9e5abd1ea35b2b0e2374ff --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5bdc64af6aeb109edfd2100768e72548b93d2225 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +vesicles 0.5196868120414728 1.8663075073239423 0.0619983550657976 0.6631308818054996 0.2339040526254295 184 Q9Y3E7,Q06481,O95219,P30825,O15127,O00400,Q8IXU6,P02786,Q8IY95,Q8IZA0,P51798,Q9UEU0,Q93050,P13473,Q8NBN3,Q7L5N7,Q9H2V7,Q13308,P11279,Q15904,Q10713,O00459,Q15392,P04439,O60476,Q9NUM4,P11166,Q9Y678,Q9UMY4,Q5VW38,Q96L92,Q9H2J7 32 +membrane 0.4577570781433129 1.8197616543865616 0.0687953095957145 0.7023076791482272 0.2339040526254295 83 P19022,P30825,O15127,Q9ULC3,P67870,P84095,Q13308,P42566,Q9UNF0,O00459,Q13740,P02786,P04439,Q9UQB8,Q9NUM4,P09496 16 +golgi 0.470754388550771 1.6179236783882611 0.1056790466630441 0.8502427337319975 0.2994239655452918 63 Q8IZA0,Q9Y678,Q5VW38,O15127,Q8NBN3,Q15904,Q8IXU6 7 +focal_adhesions 0.6469568453569143 1.2484412963308749 0.2118694937578404 0.9825350097369804 0.4038705807385988 6 Q13418,Q13177 2 +cytoskeleton 0.4755683670037088 1.2431465443484209 0.2138138368616111 0.9832532039390413 0.4038705807385988 32 Q15019,P35579,Q05682,Q9NVA2,P35580,Q96FJ2,Q16181,P06493,Q9Y6G9,Q7Z460,O43707,P60660,Q13561,Q9UHD8,P27816,P08670,Q13409 17 +cell_contact 0.4189765785427937 0.8408226959969604 0.4004472704598767 0.9998328657193382 0.6060921787542223 31 Q9UKS6,P19022,Q9NVZ3,Q9UJU6,Q9ULC3,Q9UQB8,O00459,Q13740,P42566 9 +centrosome 0.3581453875607864 0.442531049821689 0.6581049668007191 0.9999999880827112 0.699236527225764 34 P62258,Q15691,P63104,P33176,Q96FJ2,Q13442,O43237,Q2M1P5,P06493,P27348,Q9Y6G9,P23258,Q10713,Q04917,Q7Z460,P41208,Q13561,Q13409 18 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cc5b1cb1b167bc44bc586503e94bbc1354cfa8be --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARPC2", "ARPC3", "ATG13", "ATG3", "ATG7", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD3", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C1orf123", "C8orf33", "CAD", "CALD1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2A", "CDS2", "CETN2", "CHEK2", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP7", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLCN7", "CLINT1", "CLK2", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COMMD4", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1B", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DEGS1", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FANCA", "FARP1", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GOSR1", "GPAT4", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPH1", "IDI1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "INPPL1", "INTS14", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LPCAT2", "LSM14B", "LSS", "LTV1", "LZTS2", "MAN1A2", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MARK2", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED24", "MED25", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVD", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP2", "NEK9", "NEMF", "NET1", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIN4", "PIP4K2C", "PKM", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "PPM1G", "PRKACA", "PRKCA", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBBP4", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "RELA", "RER1", "RHEB", "RHOG", "RING1", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RRP36", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SARS", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCD", "SCFD1", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SLC16A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A1", "SLC33A1", "SLC35F2", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX9", "SPNS1", "SPOUT1", "SPPL2A", "SPTLC1", "SPTLC2", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM2", "STIP1", "STK26", "STT3A", "STT3B", "STX12", "STX18", "STX5", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCOF1", "TERF2", "TFRC", "TGFBRAP1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM192", 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b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df66ba8aa324d5c6ceee4f01fd30b49777be76df8dc6084db2da70fb04dd2650 +size 86740 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..62fbe4b12753188482480719a1df12e1c657d115 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +metalloprotease 7 26 2.689955231244404 0.0071461605150855 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.0095729757760163 0.0023085518548632 0.0018920992945107 4.452369837581418e-05 0.0010808437399693 +membrane trafficking regulatory protein 6 21 2.636982703756658 0.008364709650394 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0090937827788983 0.027703186905031 0.0001621832719882 0.0017538141840637 0.0138300064936424 +serine protease 5 19 2.554581403225913 0.0106315566999857 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 4.557198944336205e-05 9.216009865625694e-05 0.0001111606586644 0.0011585880107859 0.03080273588529 +protease inhibitor 4 10 2.41338221185692 0.0158052355755995 2.9101941747572817 8.470873786407767 -0.2314103697452487 0.4582528635483486 1.848429656574973 1.4867133927645466 1.0472458882274065 0.2976253017490123 0.0023797484711094 0.0112943240362007 0.0040346592713098 0.0011317572349641 0.0206839034685982 +cadherin 5 6 2.408979089445935 0.0159972145155091 1.555825242718447 3.0558252427184467 -0.2693089236279177 0.4378099575304214 1.0377767725547085 1.0517161419538543 1.2797396443463749 0.3315735399503712 0.0003886260619154 0.0034296220851759 0.0006712136127385 2.898375171077518e-06 0.0001461959825676 +cysteine protease 3 29 2.3576396660116727 0.0183915354504839 7.415048543689321 25.01941747572815 -0.1289544806835841 0.4980087250959599 4.133108887425229 4.865133695414516 1.110132682191423 0.3188225521304443 0.0054456245106909 0.3491693980885609 0.0104196950872655 0.1632106984779044 0.1311685502887974 +phospholipase 1 7 2.177323396458696 0.029456446722607 2.0266990291262137 7.405339805825243 0.812358854363279 0.2972812642592555 1.2910317153343125 1.5290934655146406 1.1524828353366978 0.2736190413418742 0.0245754818920448 0.0093923264669034 0.0346664630686661 0.1658780833937837 0.4336067804253886 +membrane traffic protein 29 70 2.175476345461296 0.0295944388409579 17.393203883495147 64.0364077669903 0.6866153002436179 0.5279969401351168 6.983388919650095 8.417857504136053 1.0746394007588131 0.378481933491251 0.1249149493821624 0.0376182203289342 0.1847545446978684 0.0767167525516637 0.0328649875506932 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7442993d74aa0f4743357c39181664e141fc117b --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 14.35 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..24dbdb4fe1ad494e4288afbe5bb8c9a9e4af1df0 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d9039b843678cf9142a421ca55cb802c74b87516 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,56 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +metalloprotease 0.7351310198892292 2.689955231244404 0.0071461605150855 0.6825676834080512 0.1665166677133811 26 Q7Z2K6,P42892,Q9UIQ6,Q10713,O75844,P02786,P55786 7 +membrane trafficking regulatory protein 0.7617979849774776 2.636982703756658 0.008364709650394 0.7391950384456948 0.1665166677133811 21 Q14108,P11279,P13473,Q8WTV0,O43731,O43760 6 +serine protease 0.7578707583920304 2.554581403225913 0.0106315566999857 0.8191624341886414 0.1701049071997716 19 O14773,Q9H3G5,P42785,Q9HB40,P10619 5 +protease inhibitor 0.8496199084295297 2.41338221185692 0.0158052355755995 0.9218429668322148 0.1968887940370359 10 Q6YHK3,Q92530,P05067,Q06481 4 +cadherin 0.9437834622248692 2.408979089445935 0.0159972145155091 0.9242447996235672 0.1968887940370359 6 Q14126,Q02487,O60245,Q14517,Q14574 5 +cysteine protease 0.6573286836976012 2.3576396660116727 0.0183915354504839 0.948698843589572 0.2101889765769599 29 Q99538,P53634,Q92820 3 +glycosidase 0.9759215219976212 2.1978026881336152 0.0279631698075766 0.9893036578939906 0.2113329286489366 4 Q9BTY2,P04066,P06865 3 +phospholipase 0.8642874266658866 2.177323396458696 0.029456446722607 0.9916361801489232 0.2113329286489366 7 Q8NHP8 1 +membrane traffic protein 0.5242718183583474 2.175476345461296 0.0295944388409579 0.9918243127015228 0.2113329286489366 70 Q9UQN3,Q9Y3E7,Q9H444,O43493,Q9UBC2,P20645,P11717,O60645,Q8TAG9,O60763,Q9H223,Q9H4M9,Q99523,Q9UHQ4,Q12907,Q8WUX9,Q96ED9,P43307,P54920,Q08379,P42566,Q9H9E3,Q9UPT5,Q9H6H4,O00429,O14976,Q9BRG1,Q92734,A6NIH7 29 +major histocompatibility complex protein 0.9640309155766932 2.15466065273199 0.0311883989851171 0.9937151792063772 0.2113329286489366 4 P55899,P01889,P04439 3 +apolipoprotein 0.9622473246135538 2.148173950255521 0.0316999392973404 0.9942244486077564 0.2113329286489366 4 P01130,Q9NPF0,Q07954 3 +transmembrane signal receptor 0.7589090888120134 1.9425251285444656 0.0520735609180906 0.9998077165750666 0.3085840646997966 9 Q99720,Q15375,P29317,O94898 4 +kinase modulator 0.8109169329476477 1.9037458844940436 0.0569432874330777 0.9999156568711544 0.3253902139033015 6 O00459,P10644,P67870 3 +hydrolase 0.6009021505898119 1.801026624244993 0.0716986836469328 0.9999932355170424 0.3584934182346644 22 P34913,P07099,P15586,O43598,Q9Y3Z3,Q68D91 6 +aspartic protease 0.856150427018384 1.7556251121305106 0.0791524414454625 0.9999981377475314 0.3837694130689092 4 P49768,Q8TCT8 2 +galactosidase 0.9777117384843984 1.7204840738434557 0.0853444861888086 0.9999993672836108 0.3924730187624867 3 P16278,P06280 2 +G-protein modulator 0.7890619776065364 1.7025516681965602 0.0886520014560321 0.9999996456119556 0.3924730187624867 5 P52565,Q9H2M9,P11274 3 +immunoglobulin superfamily cell adhesion molecule 0.9459298871063586 1.6885434288989891 0.0913069596535192 0.999999777795786 0.3924730187624867 2 P43121 1 +tubulin 0.7515106313608246 1.6693925653123427 0.0950396061009781 0.9999998849910612 0.3924730187624867 6 P04350,Q9BUF5,Q13885,P07437 4 +G-protein coupled receptor 0.8155110601647572 1.602329665493805 0.1090827289958122 0.999999990581527 0.4256886985202431 4 P48960,Q5VW38 2 +cell adhesion molecule 0.9197860962566844 1.5848138387056447 0.1130086372322458 0.9999999953537504 0.4305090942180794 2 Q08722 1 +protease 0.4873300932238822 1.5522520621842764 0.1206019233211708 0.9999999988259628 0.448751342590403 42 P78536,P28070,P28074,P28072,Q9UJ14,P49721,O75976 7 +amino acid transporter 0.7433402021496072 1.5235519426650148 0.1276206758485365 0.9999999996742696 0.4628561089236282 5 Q96QD8 1 +integrin 0.9201448106733122 1.513399229391334 0.1301782806347704 0.999999999796371 0.4628561089236282 3 P06756 1 +DNA glycosylase 0.8969102792632211 1.494001691815798 0.1351751770833575 0.9999999999189966 0.4683914103657621 2 P13051 1 +translation factor 0.6903018006309095 1.4817117820036725 0.1384170007649385 0.999999999955584 0.4683914103657621 7 Q06787,Q53EL6 2 +cytoskeletal protein 0.701706090811534 1.4697796927533004 0.1416214308061831 0.9999999999755308 0.4683914103657621 6 Q16181,Q9UHD8,Q9NVA2,P27105 4 +extracellular matrix protein 0.6958339498648058 1.4461045236278909 0.1481478871410497 0.9999999999927844 0.4683914103657621 6 P07942,P11047 2 +ion channel 0.6781545632125087 1.4317257498153633 0.1522223240767044 0.9999999999966496 0.4683914103657621 7 P51790,Q9C0H2 2 +transfer/carrier protein 0.6026830806538991 1.4139692146669196 0.157370941683359 0.9999999999987358 0.469154382259512 11 P17900 1 +calmodulin-related 0.570529546873498 1.3500002219418177 0.1770159116832803 0.999999999999971 0.4943794578208323 13 P80303,O43852,Q14257 3 +protein modifying enzyme 0.477386500270258 1.208735451540511 0.2267644971023896 1.0 0.5545790928244586 28 Q6PK18,Q9UMR5,O60678,P13674,P50897,O60476,O60725 7 +defense/immunity protein 0.8288261515601789 1.1851706355834724 0.2359499875548232 1.0 0.5551764413054664 3 O75179,Q13228 2 +protein-binding activity modulator 0.6993898887002423 1.1611824591455713 0.24556770654128 1.0 0.5651344681993085 4 Q9UNZ2 1 +carbohydrate kinase 0.6335192703993435 1.0906191360375628 0.2754405057140552 1.0 0.5876064121899844 5 P51570,Q01813,P08237 3 +small GTPase 0.5318118522463581 1.012962625993796 0.3110780129821067 1.0 0.6105275594864465 10 Q9HCN4,P11233,Q15382,P84095 4 +translation initiation factor 0.3862619376850879 0.8032392993277054 0.4218364348398777 1.0 0.7166728523595561 45 O75821,O60841,Q13347,Q92905,O43583,Q9NR50,P55010,O00303,O75153,P23588,Q9Y262,Q7L5N1,Q04637,P63241,P06730,P55884,P05198,Q9UJA5,P51665,P49770,Q9BY44,O15372,P20042,O75822,Q15056,Q13144 26 +SNARE protein 0.4670844328355901 0.7764742421681561 0.4374690236353684 1.0 0.7291150393922807 11 O15400,Q9UNK0,Q9UEU0,Q86Y82,Q12846,P56962 6 +GTPase-activating protein 0.4223524428079554 0.7272860406487934 0.4670507477017938 1.0 0.7581623080434743 20 Q07960,Q0IIM8,O60343,Q86VI3,Q9H0H5,P46060,Q9BXI6,Q8TC07,Q8N6T3,Q4KMP7 10 +replication origin binding protein 0.6579494799405656 0.6104263986655613 0.541579385310331 1.0 0.8252638252347901 3 O75419,Q13416 2 +ATP-binding cassette (ABC) transporter 0.4312192629556509 0.5691745893281174 0.5692376634005516 1.0 0.8371800673851433 10 P08183,Q9NP58,P33527 3 +secondary carrier transporter 0.3807676460214262 0.4581166069342388 0.6468686684416649 1.0 0.8846067260740718 16 Q9BXP2,O00400 2 +non-motor actin binding protein 0.3486132219147027 0.3666789892045988 0.7138584807344295 1.0 0.9550074395305308 31 P35080,Q05682,Q14247,P35611,Q9UJU6,P52907,P07737,P47756,Q15417,Q9Y6W5,Q6IBS0,Q14651,O75083,P23528 14 +actin binding motor protein 0.3807145066899825 0.3170919607255354 0.7511738247851563 1.0 0.9682351112242316 8 P06753,Q15643 2 +translation elongation factor 0.3409361584367316 0.2669510789943285 0.7895068278329465 1.0 0.9772042348447122 13 P24534,Q9NUQ8,O00178 3 +Hsp90 family chaperone 0.4192589875838935 0.2662505574321748 0.7900462485279172 1.0 0.9772042348447122 4 P08238 1 +oxidase 0.3372289454500998 0.2611479171445179 0.7939784408113286 1.0 0.9772042348447122 14 Q6ZRP7 1 +kinase 0.3287778812948778 0.2253363928199236 0.8217175902103115 1.0 0.9885324393507506 18 P35790 1 +aldolase 0.438632986627045 0.1555587389204208 0.8763808504895434 1.0 1.0 3 P04075,P37837 2 +translational protein 0.4477124183006621 0.1523292950750753 0.8789272204020557 1.0 1.0 2 P54577 1 +kinase inhibitor 0.4350668647845485 0.1521898917617948 0.8790371663014223 1.0 1.0 3 Q96P16,Q9NQG5 2 +non-motor microtubule binding protein 0.3026730286989156 0.1098050757037502 0.9125639655599608 1.0 1.0 20 Q66K74,Q15691,Q15555,P46821,P60520,P13693,O43663,Q96CW5,P78559,Q4ZIN3 10 +DNA ligase 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 1.0 2 P18858 1 +transporter 0.2974582653201362 0.0696298975744513 0.9444882398623125 1.0 1.0 58 Q99595,O60830,O43772,Q567V2,Q9C0E2,Q9H2V7 6 +mitochondrial carrier protein 0.2328559023235228 0.0486672338755304 0.96118448849913 1.0 1.0 7 Q9BSK2 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..111be7b8c8c9ba984f78f244bf2fce8e6c46e26f --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATF7IP", "ATG3", "ATG7", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP1", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCKDHA", "BCKDHB", "BCLAF1", "BCR", "BLM", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD1", "BRD7", "BRIX1", "BRPF1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK2", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMB", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GINS2", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLT1B", "GOSR1", "GOT1", "GOT2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRIG2", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN1B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MIPEP", "MKL2", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOB4", "MOCS3", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCKIPSD", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NET1", "NF2", "NFS1", "NFYB", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NR2F2", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RIPK1", "RNASEH2A", "RNF14", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", 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"signature_size": 3368, + "annotations_size": 2115, + "title": "Average number of proteins per term", + "value": 3.1257683215130023 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7a117df7304855bc42b752dcde569ca05e527db1 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f2da351b73abfce5d51935770413e40553cbd93c --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,84 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hydrolase 0.5832650230691169 2.9945475428040353 0.0027485221795024 0.9970357399189288 0.0507163077924676 99 P15586,Q08431,Q8IW92,Q8NCC3,Q9UMR5,P10253,P07686,P50897,P16278,P38571,P06865,P11117 12 +Protease 0.5901591988572099 2.9026226255923446 0.0037005225414388 0.9996067725123272 0.0507163077924676 121 Q7Z2K6,P42892,P34913,Q8NHP8,O14773,Q9UIQ6,P42785,Q13510,Q9H3G5,P55786,Q9HB40,P10619,O75844,P02786,Q99538,P53634,Q92820,Q8TCT8 18 +Cysteine protease 0.6258753940072743 2.678848772560801 0.0073875750630241 0.9999998454458768 0.0538501810192798 48 Q8TEY7,Q8NHP8,Q13510,Q6GQQ9,Q9BXI6,Q99538,P53634,Q92820 8 +Metalloprotease 0.6684566061189755 2.611260738765602 0.0090209086326964 0.9999999952532174 0.056783398089741 36 Q7Z2K6,P42892,Q9UIQ6,Q10713,O75844,P02786,P55786 7 +Receptor 0.6912206698202186 2.579911538484873 0.0098825627076062 0.999999999245968 0.0580059604356672 30 P05556,Q14108,Q6PCB8,O94898,Q13641,Q9UQB8,P20645,P11717,Q567V2,A6NIH7,Q8WTV0 11 +Protease inhibitor 0.8455376743243649 2.565866217224736 0.0102918514435201 0.999999999685505 0.0583572809733115 12 Q06481,P07942,P27105,P11047,Q92530,P05067 6 +Cell adhesion 0.9386525383846236 2.389989101490096 0.0168488727711548 0.9999999999999998 0.0740859998149533 6 Q14126,Q14574,Q02487,P43121 4 +Phosphatase inhibitor 0.9122285034215956 2.3606191158954526 0.0182444581129499 1.0 0.0766116820322722 7 Q99733,P39687,Q9BTT0,Q92688,Q01105,P55209 6 +Phosphatase modulator 0.8578759434151504 2.349827545184934 0.0187821108392911 1.0 0.0781355628655506 9 Q99733,P39687,Q9BTT0,Q92688,Q01105,P55209 6 +SLC superfamily of solute carriers 0.5728832058909347 2.30304535444094 0.0212762913933328 1.0 0.0830133822469151 49 P11166,P30825,Q96QD8,Q9BXP2,O00400,O43772,Q8IXU6,Q7L0J3,Q9H2J7,P08195,Q9H2V7,Q15043,Q9BSK2 13 +Enzyme modulator 0.5166547597528983 2.2180151425473222 0.026553799963126 1.0 0.0925227132158344 121 O60271,Q9Y3E7,Q9NVA2,Q06481,Q9UBC2,Q13200,Q9UNS2,O14737,Q12834,P43487,P84095,P05067,P55209,Q9H223,Q9Y2I1,Q9H4M9,Q9Y3A3,Q9NTK5,Q96P70,Q99733,Q9UBI6,O00410,P39687,Q9H0U9,O95373,Q9H0H5,Q9H6Z4,Q92530,Q92688,Q96ED9,P60983,P63096,P63000,Q9BTT0,O43242,Q9Y4G8,Q86VI3,P11047,P52565,O00459,P42566,P11233,P55036,Q9H2M9,O00429,P07942,P04080,P27105,P35237,P46060,Q15382,P11274,Q16181,Q96HP0,Q01105,Q96CX2 56 +Membrane trafficking regulatory protein 0.6458156000842599 2.0532665884684613 0.0400467294188033 1.0 0.1162038385940936 22 P11279,P13473,O43731,O43760 4 +Lipase 0.9214599924072664 1.9987690068998545 0.0456333526413641 1.0 0.1245888885325645 4 Q8NCC3 1 +Esterase 0.7261690342660356 1.981257515996817 0.0475624020880149 1.0 0.1280075311862934 11 Q9UMR5 1 +Aspartic protease 0.8582665307043704 1.9693026889394336 0.0489183426019499 1.0 0.1298612190549101 5 P49768,Q8TCT8,Q5BJF2 3 +Galactosidase 0.977421271538919 1.81317233862047 0.0698052447719372 1.0 0.1611769570880429 2 P16278 1 +Glycosidase 0.9753416518122408 1.804957587878303 0.0710813190900347 1.0 0.1623509609885783 2 P06865 1 +G-protein coupled receptor 0.9699940582293528 1.783822703916027 0.0744524791173346 1.0 0.1673400566771124 2 P48960 1 +Eph family 0.9649435531788472 1.7638479097838546 0.0777575888288795 1.0 0.1709289455718537 2 Q15375 1 +Serine protease 0.5565763712297582 1.7364593180414665 0.0824826516476116 1.0 0.1772464911902126 29 P34913,O14773,P42785,Q9HB40,P10619 5 +Extracellular structure 0.7083750726332381 1.7274080438029296 0.0840944070275298 1.0 0.1794749453715696 9 Q5KU26 1 +Immunoglobulin superfamily cell adhesion molecule 0.9459298871063586 1.6885434288989891 0.0913069596535192 1.0 0.1895131426488748 2 P43121 1 +Tubulin 0.7515106313608246 1.6693925653123427 0.0950396061009781 1.0 0.1940239062775761 6 P04350,Q9BUF5,Q13885,P07437 4 +Cadherin 0.9625557206537892 1.6660804250821544 0.095697396808815 1.0 0.1941324384887064 3 Q14574,Q02487 2 +Mitochondrial amino acid transporter subfamily 0.7580973103749371 1.5815154049187454 0.1137602394702002 1.0 0.2197286817164141 5 O43772 1 +Chloride channel family 0.9132501485442684 1.5588656904135174 0.1190281723407451 1.0 0.2251740469594597 2 P51790 1 +TK group 0.7231029322270788 1.5558235138671173 0.1197500651032714 1.0 0.2257320745930651 6 Q15375,P29317 2 +Translation factor 0.5136512362484223 1.4463778998211938 0.1480712370591679 1.0 0.2603247434581381 28 P24534,P23588,Q9Y262,P05198,Q53EL6,P20042,P62495,Q86TB9,Q13347,P63241,O75822,P55010,P06730,Q15056,P29692,O75153,P55884,Q9UJA5 18 +STE group 0.6366345575160425 1.4150450717624763 0.1570552814615666 1.0 0.2720490747675786 9 Q13177,Q02750,Q9H2G2,O95747,P36507,Q9P289,Q13188 7 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8885490971320661 1.399506121041103 0.1616612640923893 1.0 0.2779785150856939 3 P08195 1 +STE20 family 0.6673921325389218 1.3873482993666886 0.1653355818583395 1.0 0.282308632804657 7 Q9H2G2,O95747,Q13177 3 +Kinase modulator 0.5604064577238236 1.3487993862346 0.1774014119161626 1.0 0.2952871523523555 14 O60271,Q96ED9,O00459,P60983 4 +Translation initiation factor 0.5194442295369356 1.32657163738852 0.1846504232345311 1.0 0.3036518706642926 22 P23588,Q9Y262,P20042,Q86TB9,Q13347,P63241,Q9UJA5,P55010,P06730,O75822,Q15056,O75153,P55884,P05198 14 +Reductase 0.5309590690598955 1.2748579858936917 0.2023595122221386 1.0 0.3230115987545836 17 Q9UBM7,Q15392 2 +Other group 0.5400391806361156 1.2443745217452566 0.2133617554616673 1.0 0.3355093775475289 14 Q96KB5,Q9UHY1,P19525,O14976,Q96PY6 5 +Intracellular calcium-sensing protein 0.53942134076116 1.241200058287793 0.2145318533144462 1.0 0.3358207183755951 14 P80303,O43852,Q14257 3 +Calmodulin 0.53942134076116 1.241200058287793 0.2145318533144462 1.0 0.3358207183755951 14 P80303,O43852,Q14257 3 +Ion channel 0.5750607705997212 1.2105769070321666 0.2260575992021838 1.0 0.3486740653309267 10 Q9C0H2 1 +NAK family 0.8012477718360091 1.1175698171483868 0.2637507656592932 1.0 0.3844471877115128 2 O14976 1 +Kinase activator 0.6858593360819177 1.110124286834219 0.2669454729541305 1.0 0.3880341410982721 4 Q9Y3A3 1 +Calcium-binding protein 0.4906129309404453 1.0807406176189305 0.279812509863282 1.0 0.3990582996364405 18 Q02818,P80303,O43852,Q14257 4 +Acyltransferase 0.5523352369049006 1.042541537354894 0.2971606780488254 1.0 0.4163777890119307 9 Q9UJ14 1 +Guanyl-nucleotide exchange factor 0.6143574379882981 1.0158117077370044 0.3097190597216119 1.0 0.4292612667745024 5 Q96HP0,Q9Y4G8,P11274 3 +Transporter 0.4439639547290508 0.9896015558910404 0.3223689092236326 1.0 0.4407306031079399 199 Q9BQE5,O43493,P30825,O00560,Q9BXP2,O00400,Q8IXU6,O43760,Q9BSK2,Q99523,Q9UEU0,P08183,Q93050,P13473,Q9HC07,O43772,P17900,Q9H2V7,Q15043,P33527,O15400,P11279,Q7L0J3,Q9C0E2,O43731,P11166,Q9Y678,Q7Z7H5,Q14444,O60664,Q96QD8,Q9Y619,P35606,O60684,Q9NP58,Q9H2J7,P08195 37 +SNARE protein 0.514960007558211 0.9364004915649604 0.3490670249639791 1.0 0.4634505698674299 10 O15400,Q9UNK0,Q9UEU0,Q86Y82,Q12846,P56962 6 +Small GTPase 0.4316232711357972 0.8130879724105323 0.4161676218420314 1.0 0.5199022564653847 23 Q15019,O00429,Q9NVA2,Q96P70,P63000,O15397,P84095,O95373,Q15382,Q16181,Q9UHD8,P11233 12 +STE7 family 0.7094474153297736 0.7744860152106138 0.4386434350896933 1.0 0.5384392717438777 2 Q02750 1 +Translation elongation factor 0.5892252840200352 0.7563996582261708 0.4494096128513343 1.0 0.5459513677085422 4 P24534,Q53EL6 2 +ERK subfamily 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.5574535884566004 2 P28482 1 +MAPK family 0.6972667855020854 0.7315997983949791 0.4644128713288558 1.0 0.5574535884566004 2 P28482 1 +PKN family 0.670528817587648 0.6405598507612354 0.5218086918914795 1.0 0.5971551035537367 2 Q16512 1 +Replication origin binding protein 0.6579494799405656 0.6104263986655613 0.541579385310331 1.0 0.6115538707588629 3 O75419,Q13416 2 +ATP-binding cassette transporter family 0.4473343184856649 0.5930288962726052 0.5531618139435797 1.0 0.6173362947571398 9 P08183,P33527 2 +CDK family 0.4775498067201988 0.5171634395148083 0.6050420714175335 1.0 0.6539982968582995 5 P24941,P11802,P21127,P06493 4 +Growth factor 0.4764954896752524 0.5137420374628285 0.6074323572409324 1.0 0.6553641514349493 5 Q7Z4V5 1 +G-protein 0.3659745230154906 0.4847072124630021 0.6278840495889959 1.0 0.6706943256973366 32 Q15019,Q9NTK5,Q9NVA2,O00429,Q96P70,P63000,P63096,Q9UBI6,O15397,P84095,O95373,Q15382,Q16181,Q9UHD8,P11233 15 +Enzyme 0.3018664842486392 0.4483723221696487 0.6538845134709068 1.0 0.6887279611508804 662 P42892,Q8NHP8,O14773,Q9UIQ6,P15586,Q13423,O15127,Q9HB40,Q5BJF2,Q9UBM7,Q9UMR5,P50897,Q6ZRP7,P02786,Q99538,P06865,P42785,Q8NCC3,P10619,P10253,P16278,P53634,Q92820,Q8TCT8,P11117,P34913,Q13510,Q9H3G5,Q08431,Q8IW92,O00115,P07686,Q9UJ14,P38571,Q15392,Q7Z2K6,O43924,Q16850,O75844,P55786 40 +SLC25 family of mitochondrial transporters 0.3649889666147593 0.40847260208742 0.6829267411024893 1.0 0.7122568824177993 20 O43772,Q9BSK2 2 +Chaperone 0.346266448529506 0.401344643255671 0.6881663994516969 1.0 0.7160233131478491 39 Q99471,Q99426,O14967,Q15185,O75347,Q9UHV9,O14656,P07900,O00170,P08238,Q14203,O60476 12 +Ubiquitin-protein ligase 0.3668891165176919 0.3980988299767635 0.6905573368099434 1.0 0.717352046833512 17 Q9Y4X5,Q13617,P63208,P46934,Q96PU5,Q96J02 6 +G-protein modulator 0.3510119169052162 0.3802926339047821 0.7037282028141165 1.0 0.7276203801990391 30 Q9H2M9,O00410,Q9Y4G8,P43487,Q9H0H5,Q86VI3,P52565,Q9H6Z4,P46060,P42566,Q9H223,Q9H4M9 12 +Microtubule family cytoskeletal protein 0.3323557391759109 0.3576342624841805 0.7206170341814904 1.0 0.7391391984936238 48 Q15691,P23258,O43663,Q13409,Q66K74,P04350,P46821,Q96FJ2,P60520,O43237,Q13561,Q9Y266,Q9BUF5,Q2M1P5,P13693,P78559,Q8IVD9,P07437,Q13885,Q96CW5 20 +GSK family 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.7613516494441449 2 P49840 1 +GSK subfamily 0.5588235294117758 0.3250375161193527 0.7451526781793758 1.0 0.7613516494441449 2 P49840 1 +Protein arginine methyltransferase 0.4341638151497272 0.2977257354334839 0.7659124996434032 1.0 0.781430263746164 4 O60678 1 +CAMK group 0.3804283164782808 0.2833565859603951 0.7769035045027879 1.0 0.79111743477294 6 P54646,P54619,Q13555,Q7KZI7,O96017 5 +Hsp90 family chaperone 0.4192589875838935 0.2662505574321748 0.7900462485279172 1.0 0.8041134820195115 4 P08238 1 +Vesicle coat protein 0.3358749325331711 0.2598913729697681 0.7949475660575953 1.0 0.8087128918767744 23 Q9Y678,P49755,Q7Z7H5,O95487,P48444,P35606,Q9UBQ0,P09496 8 +Non-motor microtubule binding protein 0.3347917768215624 0.2523461525559959 0.8007735175098634 1.0 0.814248071891039 18 Q66K74,Q15691,P46821,P60520,P13693,O43663,Q96CW5,P78559 8 +Tudor domain 0.5130718954248462 0.2355654950825179 0.8137698509290547 1.0 0.8270654659850797 2 Q12888 1 +HDAC class I 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.8762965325792866 2 Q92769 1 +Histone deacetylase 0.4658348187760069 0.1704001632916517 0.8646954437319012 1.0 0.8762965325792866 2 Q92769 1 +Mutase 0.4144970307795694 0.1350954087629105 0.8925364401779063 1.0 0.9036450794524996 3 Q9NRG1 1 +ROCK subfamily 0.4168152109328679 0.129271465895114 0.8971428488767188 1.0 0.9074400408293928 2 O75116 1 +DMPK family 0.4168152109328679 0.129271465895114 0.8971428488767188 1.0 0.9074400408293928 2 O75116 1 +Serine protease inhibitor 0.3969102792632304 0.1188668488306178 0.9053808463093458 1.0 0.9153348422295728 2 P35237 1 +Na+/K+-ATPases 0.3612596553773148 0.1069634169925892 0.9148180022141504 1.0 0.9235513482973404 2 P54709 1 +DNA ligase 0.3544266191325091 0.1054578069137515 0.9160125484460158 1.0 0.924316097310746 2 P18858 1 +PI3/PI4 kinase family 0.3098633392751134 0.0996804612654076 0.9205980129241802 1.0 0.9280575773759014 2 Q9BTU6 1 +Protein methyltransferase 0.2571314668746254 0.0668941324270749 0.9466659842219992 1.0 0.9529581554635806 7 O96028,O60678 2 +Protein kinase 0.2957938408589043 0.0663480495661617 0.9471007294489108 1.0 0.9529581554635806 68 P54619,Q96KB5,P19525,Q9UHY1,Q15118,P67870,Q9Y6K9,Q2M2I8,Q9H2G2,Q13308,Q02750,O95747,Q9P289,Q13177,Q13418,O14976,Q96PY6,P06493,Q15375,P29317,Q96SB4 21 +Non-motor actin binding protein 0.2954554394876085 0.0604336517912506 0.951810257373966 1.0 0.9572414143347304 27 Q14247,Q9NYL9,P35611,Q9UJU6,P52907,P47756,Q15417,Q9Y6W5,Q6IBS0,Q14651,O75083 11 +Writer 0.2515947551698435 0.0496927541177619 0.9603672307038852 1.0 0.9644713641684318 8 O96028,O60678 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9f5cc1e53defb9d8590a40455807908d6830a8e0 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S14, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5'-nucleotidase domain-containing protein 3", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AF4/FMR2 family member 4", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 6, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Adhesion class", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Apoptosis-stimulating of p53 protein 2", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Breakpoint cluster region protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "Bromodomain-containing protein 7", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 3", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CD97 antigen", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-8", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline transporter-like protein 1", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coup transcription factor 2", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cystine/glutamate transporter", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA helicase MCM8", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA repair protein complementing XP-C cells", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC6", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 6", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase clk2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "Dystroglycan", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Embigin", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 2", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD2", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Lethal(3)malignant brain tumor-like protein 2", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucine-rich repeats and immunoglobulin-like domains protein 2", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 2B", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MAST family", "MAX gene-associated protein", "MCU family", "MIF4G domain-containing protein", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MSN subfamily", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metallo-beta-lactamase domain-containing protein 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear envelope pore membrane protein POM 121C", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OCIA domain-containing protein 2", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphoribosyltransferase domain-containing protein 1", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Pirin", "Plakophilin-2", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA cleavage complex 2 protein Pcf11", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilin-1", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ENL", "Protein ERGIC-53", "Protein Hook homolog 2", "Protein LSM14 homolog B", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoblastoma-associated protein", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonucleoprotein", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 3", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek1", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 1", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 10", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucose:glycoprotein glucosyltransferase 2", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase BAP1", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 26B", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WNK family", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "ZZ-type zinc finger-containing protein 3", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 292", "Zinc finger protein 622", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1B", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG7", "ATIC", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2", "ATXN2L", "AUP1", "AURKA", "BAG6", "BAIAP2", "BAK1", "BAP1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCKDHB", "BCLAF1", "BCR", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBR4", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC45", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CEBPZ", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK2", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMB", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GINS2", "GIPC1", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRIG2", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LTN1", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN1B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MASTL", "MAT2A", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED25", "METTL14", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF4GD", "MIPEP", "MKRN2", "MLLT1", "MMS19", "MOB4", "MOCS3", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS14", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NR2F2", "NRBP1", "NRDC", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSEN1", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SAE1", "SALL2", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK26", "STK3", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF10", "TAF15", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM259", "TMEM38B", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIP4", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWNK", "TXLNA", "TXNDC12", "TXNDC17", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UCHL5", "UCK2", "UGGT1", "UGGT2", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VRK1", "VTI1B", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR82", "WIZ", "WNK1", "WRNIP1", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF281", "ZNF292", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAK1", "ABCB1", "ABCB6", "ABCC1", "ACP2", "ADD1", "ADGRE5", "AIP", "ANP32A", "ANP32B", "ANP32E", "APLP2", "APOL2", "APP", "ARCN1", "ARHGDIA", "ARIH1", "ASAH1", "ATP1B3", "ATP6V0A1", "BAIAP2", "BCR", "CALU", "CAMK2G", "CAPRIN1", "CAPZA1", "CAPZB", "CDC20", "CDC45", "CDK1", "CDK11B", "CDK2", "CDK4", "CHEK2", "CHMP3", "CLCN3", "CLGN", "CLTA", "CLUH", "CNN3", "COLEC12", "COPB2", "COPG1", "COPS3", "CPVL", "CSNK2B", "CSTB", "CTSA", "CTSC", "CTTN", "CUL2", "CYP51A1", "DBNL", "DCTN1", "DCTN2", "DHCR24", "DHCR7", "DNASE2", "DNM1L", "DOCK6", "DSC2", "DSC3", "DSG2", "DYNC1I2", "DYNC1LI2", "DYNLL2", "ECE1", "EEF1B2", "EEF1D", "EHD1", "EHD4", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3B", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4H", "EIF5", "EIF5A", "EMB", "EPHA2", "EPHA7", "EPHX2", "EPS15", "EPS15L1", "ERMP1", "ETF1", "GAA", "GABARAPL2", "GAK", "GGH", "GGT7", "GLB1", "GLB1L2", "GM2A", "GMFB", "GNAI1", "GNG12", "GNS", "GSK3A", "HDAC2", "HDGFL2", "HEXA", "HEXB", "HOOK2", "HSP90AA1", "HSP90AB1", "IGF2R", "IKBKG", "ILK", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP3", "ITCH", "ITGB1", "KCTD12", "KDELR3", "KIF7", "KPNA6", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LGMN", "LIG1", "LIPA", "LNPEP", "LRIG2", "M6PR", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAPK1", "MAPRE1", "MARK2", "MCAM", "MFGE8", "MOB4", "MPV17L2", "NAP1L1", "NAP1L4", "NEDD4", "NEDD4L", "NEK1", "NISCH", "NNT", "NPEPPS", "NRBP1", "NSD2", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "OLA1", "ORC2", "OTUD7B", "OXSR1", "PAK2", "PATL1", "PBK", "PDCD4", "PDCD5", "PDE6D", "PDK1", "PFDN2", "PFDN5", "PI4K2A", "PIK3R2", "PKN1", "PLA2G15", "PLBD2", "PLIN3", "PLS1", "PMPCA", "PPT1", "PPT2", "PRC1", "PRCP", "PRKAA2", "PRKAG1", "PRMT3", "PRTFDC1", "PSEN1", "PSMD2", "PSMD3", "PSMD4", "PSMF1", "PTGES3", "PTK7", "QSOX2", "RAB3GAP2", "RAC1", "RACGAP1", "RALA", "RANBP1", "RANBP3", "RANGAP1", "RAPGEF2", "RCN2", "RHEB", "RHOG", "ROCK2", "SCAMP2", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SEC24B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SET", "SKP1", "SLC12A9", "SLC25A15", "SLC25A20", "SLC25A33", "SLC2A1", "SLC33A1", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC6A15", "SLC7A1", "SLK", "SORT1", "SPAG9", "SPNS1", "SPPL2A", "SRPK1", "STK26", "STK3", "STOM", "STX12", "STX17", "STX4", "STX7", "STX8", "SV2A", "SYNGR2", "TBC1D10A", "TBCA", "TBCB", "TFRC", "TGOLN2", "TMED10", "TMED4", "TMEM165", "TMEM97", "TMOD3", "TOR1A", "TP53BP1", "TPBG", "TPP1", "TPT1", "TRMT6", "TSPYL1", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBG1", "TUBGCP3", "TWF2", "UNC119B", "USP33", "VPS29", "VTI1B", "WASF2", "WDR1", "XPO4", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e5dbc6499a0fe37b0207d708cd0d353ad62d1b4d --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53d3d66ab8e6a00212bcec1e0b29f0fc90e3468b8fbb519d09fedca7a137a0c8 +size 217233 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ac8cf61ab14dc2273eaa55f68f9d4cb4293c3b20 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin", "2": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f0ed2a98044449096ffd5990ba57393c8c792b0d --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2269090401ce99d87d90e789d7f8f5265d64a6ab62094747ec858e9fb2ff2c8f +size 129670 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bd27ff589b1e250ad4c27dfa9dd30a01aae10f4a --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec89feaf8e2f11e638fb8f753afd08a2af824eb2a07a6a8c7d8655e7bfa029e3 +size 128456 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..bc2f43f983ca7caa665205165c91dd0d3ba3df82 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c786d6d42f3b97edfe11d7116f7cca2e8cfe3cb7e3f98487e9deb54f01c3091 +size 128138 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ebf842c06989ec2d085d50068c901ec5ed94b285 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43513a54030c24d2181d27b6ee92647f7c3b0acc70834978df67c421e61b2e13 +size 82995 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2def49aea4ca8ecdd765117d817e37c90d9cd107 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 265 2604 inf 0.0 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.8508519028991948 0.7097245108839214 0.9570105950519804 0.5118571520921474 0.1405619381757334 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8a6a9cbf57ec37b3cf5ec498218a9039ab88c948 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 841.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a3cb3b3fc40f07ddde1bb3cedf3b15554debe814 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..112956aeea6e9a40aabffb21ac27274e802c2ced --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2045939095846477 inf 0.0 4e-18 4e-18 2604 Q6UXD5,Q8NHP8,O14773,Q06481,O43493,P15586,O00584,O75503,P61916,Q9HB40,Q92859,Q9UMR5,Q5KU26,Q86UY6,P50897,P02786,P07602,Q9NPF0,Q9UBG0,O75976,Q9C0H2,Q14108,Q8IZA0,Q07954,P22466,Q08380,P54802,Q8IV08,Q9UM22,P13473,Q8NCC3,Q14517,Q14574,P48960,O43772,P17900,Q8TCT8,O00461,P11117,Q6YHK3,Q9NQX7,Q02487,Q9H3G5,Q92542,O15118,P11279,Q08431,O94813,Q969R5,Q13641,P02792,Q92896,O60637,O00115,Q9UJ14,Q15392,P04439,Q9NUM4,P43121,P01889,Q99595,O43852,P07942,O43657,Q9P273,Q9Y624,O43505,P27105,Q96QD8,Q8NB90,O95456,Q86VP1,Q14257,O75844,A6NIH7,Q01105,P10321,Q13137,P08195,Q14126,Q9NV96,Q9BQE5,P13591,Q6PCB8,O60245,O95219,O94898,P30825,Q13423,Q7LGA3,Q9H1E3,O15127,P84095,P20645,O00170,Q567V2,Q6ZRP7,Q9Y6N7,O95772,Q10472,Q9H9Q2,P78310,P55209,O43760,P48723,P80303,Q13685,Q15643,Q8NB78,Q9UEU0,Q13438,Q99733,Q9H173,P39687,Q93050,Q14739,P55010,P49459,A9UHW6,Q92530,Q92688,P07199,Q13740,Q96ED9,Q9H2V7,Q9UHG3,P49321,Q15043,O94992,O15260,P19022,Q92520,Q96ES7,Q9H8M7,Q9NSV4,P28070,Q13309,Q9BTT0,Q9Y4G8,Q86VI3,P11047,P67809,P28072,Q10713,O00459,Q32P28,Q96PU5,Q9C0E2,P07197,O95831,P10644,Q8N122,Q9P016,Q9Y678,Q9BZH6,Q9UMY4,P09429,P04080,Q14444,Q7Z4H7,Q96ST2,Q9ULC3,Q8N3F8,Q92692,P35613,P35606,O60684,Q92734,Q96L92,Q08722,Q9HC35,Q9BU89,Q9UQB8,P49005,P13051,O43847,P23396,O15347,Q8WVB6,Q9Y3E7,Q9UMX5,Q9BXW9,Q6GQQ9,P78318,O00560,P26583,P67870,Q14118,Q9UKJ3,Q9Y6K9,Q8NE01,Q9Y4B6,Q9BXI6,P16949,Q8IY95,Q9H4M9,Q9BSK2,Q8TEY7,Q9GZM5,Q12899,O14967,O43719,O75179,P60520,Q86X10,Q9H0U9,Q9NR50,Q9HC07,Q9H0C8,Q9H6Z4,Q9H061,O95218,Q7L5N7,P60900,P06753,Q13308,Q9BZX2,Q8NBX0,Q6IN85,P60983,P24534,P23588,O95429,O15400,Q9NZB2,Q9HBH5,Q9BW61,Q9H814,Q8N0X7,Q86TB9,Q7Z4V5,Q06787,P63241,P53999,P13693,Q9Y3Z3,Q9Y376,Q9UQ84,Q9NRF9,Q9H3P7,Q8TD16,P78559,P42566,P11233,P05198,O75312,Q9P2S5,Q9H993,Q9C0C9,Q99536,Q99426,Q7Z7H5,P62913,P61970,P61513,O75347,O60664,P43034,O75822,Q9Y619,Q9UNF0,Q9NP58,Q9H9C1,Q96D46,Q86Y37 265 +Tclin 0.4270066410461693 1.5655620389507767 0.1174511828519218 0.393326606401515 0.2349023657038436 91 P05556,O43924,O96000,P28074,P06280,P10253,P49721,O43678,P29317,Q7L0J3,Q99720,Q9Y2I1 12 +Tchem 0.4661728015466875 0.8890366717682245 0.3739833715203262 0.8464168831533914 0.3739833715203262 330 P55899,P42892,Q9UIQ6,P01130,Q5BJF2,Q9UBM7,Q9BTY2,P05067,P11717,O00400,Q99538,P06865,Q4J6C6,Q99523,P04066,P42785,P07099,P08183,P10619,O00754,P16278,Q9H773,Q02818,P53634,Q92820,P34913,P33527,Q13510,P10586,Q15126,Q15904,P51790,P07686,P38571,Q8WTV0,P06756,P11166,P04062,P35790,Q53EL6,Q96PY6,Q15375,Q16850,Q9H2J7,P55786,O14786 46 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..35cd86508808799568de1fab159f9307ce9724ba --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC10", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf98", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf131", "C1orf35", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG4", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD3", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFB", "NELFCD", "NEMF", "NENF", "NEO1", "NES", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NGDN", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TATDN1", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", 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overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cell adhesion 23 47 3.939371030081413 8.169550441183837e-05 9.004854368932039 31.9126213592233 -0.1685688840508537 0.5387339485409223 5.396868539008087 6.001386241344262 1.170054868114176 0.3444078437648591 7.190990304830431e-05 0.0014406402152657 6.378806863282616e-06 2.2872048207591638e-11 2.073243360805442e-07 +Endocytosis 5 38 3.1095321917978382 0.0018738386391601 8.983009708737864 34.88834951456311 -0.1637276916549875 0.598617857723687 4.673017223462752 5.456105531160478 0.942996205009964 0.317416890130997 0.000125316126263 6.771207588758109e-06 0.0003481376424805 0.0089829519401393 0.0023542271973535 +Cholesterol metabolism 8 25 2.813492361058445 0.0049006550520869 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.005770728097185 0.0204019662414969 0.0009534889418974 1.0995319586725862e-06 4.717474112626933e-05 +Sterol metabolism 8 27 2.797110955409612 0.0051561822692456 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 0.0069121244314848 0.0230307909850112 0.0012175599782738 1.952015541418424e-06 8.478951592637114e-05 +Steroid metabolism 8 28 2.7842815706797555 0.0053646440843375 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 0.0100666740230864 0.0296703391700837 0.0020253160845859 6.375644196764208e-06 0.0002790542910114 +Chemotaxis 3 5 2.1999807924478487 0.0278082578159746 1.7354368932038835 4.002427184466019 0.2871320003941985 0.5679311571254584 1.1386444646558112 0.6212217308438713 0.8445710744066323 0.3074074620410176 0.1226742139485862 1.0 0.1459927402947744 0.0063676045893722 0.0063533232968262 +Lipid transport 6 23 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-0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 170, + "title": "Average number of proteins per term", + "value": 32.48235294117647 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5e83614635a16482fd0cb51016dc865edc7e46b4 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6f4234e80d3fdb76b539569afba49c85023c18ba --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,47 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cell adhesion 0.8201420076770494 3.939371030081413 8.169550441183837e-05 0.0137927986348108 0.0138882357500126 47 Q14126,P13591,O60245,Q92859,P05067,P78310,P05556,Q08380,Q14517,Q14574,P48960,Q13740,P19022,Q02487,P10586,Q08431,P11047,P43121,P06756,P07942,Q9P273,Q92692,P29317 23 +Endocytosis 0.73763061609448 3.1095321917978382 0.0018738386391601 0.273016429018913 0.1013321660374873 38 Q99523,P01130,P05067,P02786,Q9UBG0 5 +Cholesterol metabolism 0.7662912395780718 2.8134923610584455 0.0049006550520869 0.5661946937350713 0.1013321660374873 25 P04062,O15118,P01130,P61916,Q14739,Q9UBM7,Q16850,Q15392 8 +Sterol metabolism 0.7463589104422027 2.797110955409612 0.0051561822692456 0.5847267793310618 0.1013321660374873 27 P04062,O15118,P01130,P61916,Q14739,Q9UBM7,Q16850,Q15392 8 +Steroid metabolism 0.7352413216623347 2.7842815706797555 0.0053646440843375 0.5992608363575247 0.1013321660374873 28 P04062,O15118,P01130,P61916,Q14739,Q9UBM7,Q16850,Q15392 8 +Chemotaxis 0.9194704969585236 2.1999807924478487 0.0278082578159746 0.9917238617994056 0.2486387710712568 5 O94813,P09429,Q9Y6N7 3 +Lipid transport 0.6631844196385661 2.180078810969393 0.0292516201260302 0.993571129926319 0.2486387710712568 23 Q9NV96,Q9BQE5,O15118,P01130,P61916,Q99720 6 +Amino-acid transport 0.8094420680399042 2.152883425117847 0.0313278414443223 0.9955325574934636 0.2536063355016569 9 Q9H2J7,P08195,Q96QD8 3 +Lipid degradation 0.7043687365602449 2.0639959147677702 0.0390181037271193 0.9988476482958394 0.3007231335593139 14 Q8NHP8,Q8NCC3 2 +Sphingolipid metabolism 0.7837903918115897 2.0467150466969737 0.0406860710109659 0.9991423155012225 0.3007231335593139 9 P17900,P07602,Q13510 3 +Angiogenesis 0.6719622700226761 1.9806331630127545 0.0476324270910031 0.9997506657423028 0.3050190207479851 16 Q08431,Q13685,O14786,P29317 4 +Sodium transport 0.8121080508342127 1.9734510401468148 0.0484441974129152 0.9997843127228084 0.3050190207479851 7 Q96QD8 1 +Notch signaling pathway 0.7453714141625948 1.8853473300540216 0.0593829600136726 0.9999697877444844 0.3481070069767014 9 P49768,P78536,P05067,Q92542 4 +Cholesterol biosynthesis 0.6273121904996288 1.718784142231481 0.0856536840660087 0.9999997551938664 0.3854301264936654 15 Q16850,Q14739,Q9UBM7,Q15392 4 +Detoxification 0.950980392156864 1.7085605891492237 0.0875323741632034 0.9999998274285282 0.3854301264936654 2 P34913 1 +Aromatic hydrocarbons catabolism 0.950980392156864 1.7085605891492237 0.0875323741632034 0.9999998274285282 0.3854301264936654 2 P34913 1 +Adaptive immunity 0.5986867842180547 1.6400159597518589 0.1010018486050661 0.9999999862280392 0.4187403777688916 17 P01889,P09429,Q13740,P04439,P10321 5 +Differentiation 0.4406980147379837 1.6360797951064667 0.1018228882505252 0.999999988209364 0.4187403777688916 99 Q96SB4,Q99598,P17931,Q12834,Q9Y6N7,P16949,Q96A49,Q99523,Q9GZM5,Q13685,Q9H0H5,Q96EK7,Q04721,Q9Y2W6,O94813,Q9Y4G8,Q96PU5,O75312,Q99426,Q14444,Q9P273,P43034,Q8NB90,Q9H9C1,P29317,Q08J23,O14786 27 +DNA excision 0.8223829582054885 1.6283367310784584 0.1034535050958438 0.9999999913427712 0.4187403777688916 4 P49005 1 +Sterol biosynthesis 0.5877019655041595 1.581494306902204 0.1137650596386523 0.999999998788544 0.4331618559252921 17 Q16850,Q14739,Q9UBM7,Q15392 4 +Sensory transduction 0.7143036171642376 1.520484581266172 0.1283892310268446 0.999999999928412 0.4454320260115018 6 P50897 1 +Vision 0.7143036171642376 1.520484581266172 0.1283892310268446 0.999999999928412 0.4454320260115018 6 P50897 1 +Neurotransmitter transport 0.9183299526657762 1.5068570503550014 0.1318473024700208 0.99999999996358 0.4482808283980709 3 Q7L0J3 1 +Symport 0.6613553131328928 1.4405745810468993 0.1497049058802051 0.9999999999989362 0.4801855471629221 8 Q96QD8 1 +Inflammatory response 0.5971020594925537 1.3877357993704167 0.1652175106335627 0.9999999999999536 0.512694011520386 11 Q8IV08,P09429 2 +Neurogenesis 0.4485811700108822 1.3277048684982269 0.1842756245886567 0.9999999999999992 0.5364706252586142 49 Q99426,O94813,Q9Y4G8,Q12834,Q06787,P43034,Q15375,Q9Y6N7,P16949,P55209,O14786 11 +Purine salvage 0.6810571768365051 1.2778043708868057 0.2013184128647487 1.0 0.5568981145851288 5 P00491,P00492,P07741 3 +Immunity 0.4000197437728131 1.2597470292463249 0.2077606340451911 1.0 0.5568981145851288 84 O15347,P19525,Q6GQQ9,O00584,P17931,Q9UJU6,P26583,Q9BUI4,Q13283,Q12899,O75179,Q8IV08,O95801,P17812,Q13740,O94992,P54578,Q13309,P25786,Q9Y3Z3,Q9UQ84,P04439,Q96J02,P01889,P09429,Q96RS6,P10321 27 +Antiport 0.6049884048348373 1.1293474176195395 0.2587513052305712 1.0 0.5643039461345625 7 P51790 1 +Innate immunity 0.4156453967738211 1.1217093561424667 0.2619860371596718 1.0 0.5643039461345625 62 O15347,O94992,P01889,Q12899,P09429,P19525,O75179,O00584,P17931,Q13309,P26583,P10321,O95801,Q9Y3Z3,P04439,Q9BUI4,Q13283,Q96J02 18 +Steroid biosynthesis 0.4625872269053368 0.98625615652905 0.3240074285772589 1.0 0.6461334955344563 22 Q16850,Q14739,Q9UBM7,Q15392 4 +Cilium biogenesis/degradation 0.4250098162696938 0.7729488434489882 0.4395526566144871 1.0 0.6872425221232071 23 Q9P2S5,Q96J42,Q96PY6,Q15154,A6NIH7,Q9H4M9 6 +Oogenesis 0.6772841931465028 0.6698923720832912 0.5029264026926896 1.0 0.7060520358217462 3 Q96RD7 1 +Cell shape 0.4892303747465081 0.6291535975185097 0.5292485041634989 1.0 0.7060520358217462 6 P35580,P35579,Q96AC1,P15311 4 +Autophagy 0.3821895768642143 0.6194846054119527 0.5355971604062484 1.0 0.7060520358217462 35 Q13137,P13473,P09429 3 +Glycogen biosynthesis 0.6424333060989125 0.5643162411007863 0.5725389303080455 1.0 0.7411650797521976 3 P46976 1 +Purine biosynthesis 0.4400119083060594 0.5635681686906422 0.5730480550221966 1.0 0.7411650797521976 9 P30520,P22102,P49915,O15067,Q06203,P31939,P30566,P22234 8 +Exocytosis 0.4008288842103467 0.5575512172285418 0.5771508759061201 1.0 0.7411650797521976 16 Q15833,Q12765,Q9UPT5,P40222,O60645,Q8TAG9,P11233 7 +Pentose shunt 0.6434937611408278 0.5535999211073593 0.5798526800414252 1.0 0.7411650797521976 2 P52209 1 +Ion transport 0.342581860784481 0.4534183619690221 0.6502475168574706 1.0 0.7952667472357554 60 Q93050,Q96QD8,Q15904,P51790,Q8NE01,Q9H2J7,Q15043,Q9C0H2 8 +Pyrimidine biosynthesis 0.3957798388873443 0.2853352782904569 0.775387287558597 1.0 0.8983035277665963 5 Q9NRF8 1 +Host-virus interaction 0.4019230206802375 0.2161448520374222 0.8288748390611003 1.0 0.9265685052077586 273 P13591,P01130,P28074,Q14118,Q9Y6K9,Q9Y4B6,P02786,Q9H9Q2,P78310,O43760,Q14108,P05556,Q8IZA0,O75179,P39687,Q92688,P49721,O15118,P11279,P28070,Q13309,Q06787,P28072,Q9Y3Z3,Q96PU5,P04439,Q9H3P7,Q8WTV0,P06756,P01889,Q8N122,P09429,Q9Y624,Q92692,Q15056,P35613,O60684,P29317,Q01105,P10321,P13051,O14786 42 +Nucleotide biosynthesis 0.2850054935937908 0.1104905262696925 0.912020362809751 1.0 0.9917349833731574 5 O60256,Q14558 2 +Sodium/potassium transport 0.3612596553773148 0.1069634169925892 0.9148180022141504 1.0 0.9917349833731574 2 P54709 1 +Fucose metabolism 0.3475935828877096 0.1041509243527397 0.917049578775544 1.0 0.9917349833731574 2 Q9Y2G5 1 +Hydrogen ion transport 0.2811255397500553 0.026554815440981 0.978814812592113 1.0 1.0 20 Q15904 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3b8c68dfb19229e46d7d1f25e0937b2edbc7b494 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADAM17", "ADAR", "ADGRE5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP2", "ARG2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARMC10", "ARMT1", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BAK1", "BANF1", "BAP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRIX1", "BRMS1L", "BRPF1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP8", "CBL", "CBR4", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPF", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "COASY", "COG2", "COG5", "COG7", "COMMD3", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ8A", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1B", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC2", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPY30", "DPYSL2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FRYL", "FTL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGT7", "GHITM", "GINS2", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "INPPL1", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPCAT2", "LPGAT1", "LRP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAGI3", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL14", "MFAP1", "MFGE8", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MIF4GD", "MINDY3", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMS19", "MOB4", "MOCS1", "MOCS3", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL41", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCKAP1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NELFA", "NELFCD", "NEO1", "NES", "NFS1", "NFYB", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NR2F2", "NRDE2", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "POP1", "PPAT", "PPCDC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCA", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINH1", "SET", "SETD1A", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPAG5", "SPATA5", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPOPL", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK3", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNGR2", "TAF10", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TAX1BP1", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TDP2", "TDRKH", "TECR", "TEFM", "TENM3", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TK1", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM14C", "TMEM214", "TMEM30A", "TMEM38B", "TMF1", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TP53BP2", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWNK", "TXLNA", "TXNDC15", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VMP1", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRAP73", "WRNIP1", "XAB2", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF1", "YTHDF3", "YWHAB", "YWHAE", "ZBTB33", "ZC3H11A", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZMYND8", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAMP", "ACBD3", "ADAM17", "ADGRE5", "ADSL", "ADSS", "ALCAM", "ANKRD17", "ANP32A", "ANP32B", "APOL2", "APP", "APRT", "ASAH1", "ATIC", "ATP1B3", "ATP6AP1", "ATP6V0A1", "BSG", "CALCOCO2", "CAPRIN1", "CDC20", "CDH2", "CLCN3", "CNNM3", "COPS7B", "CTPS1", "CTPS2", "CXADR", "CYP51A1", "DAG1", "DBNL", "DCAF1", "DHCR24", "DHCR7", "DSC2", "DSC3", "DSG2", "EHD1", "EIF2AK2", "EIF4H", "EPHA2", "EPHA7", "EPHX2", "EXO1", "EXOC3", "EXOC6", "EXOC7", "EZR", "F11R", "FAM120B", "FAT1", "FERMT2", "FMR1", "G3BP1", "GART", "GBA", "GM2A", "GMPS", "GYG1", "HEXIM1", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGB3", "HPRT1", "IKBKG", "ITCH", "ITGAV", "ITGB1", "KIAA0319L", "KPNA6", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LBR", "LDLR", "LGALS3", "LGALS3BP", "MCAM", "MFGE8", "MRC2", "MYH10", "MYH9", "NAP1L1", "NCAM1", "NCSTN", "NECTIN2", 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a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6a3658fe3c83839042c9acff3fdf449399d8c078 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:512ffe8bb03ff42210824c0e14d0d84b391ee56c882459074dea59f433f88afd +size 80882 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d5fe7cd456684beee7d2aeabf1991489f414b84a --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycogen storage disease 1 10 2.463771303310487 0.0137483802861282 3.2888349514563107 9.320388349514564 -0.2974193944938303 0.4886859424188128 1.974736458253378 1.2900936387555249 1.0050457470265506 0.3124720031873405 0.0082254277129148 0.0802348466038066 0.0117676307173903 0.0635022977163126 0.0470360579614364 +Gangliosidosis 4 5 2.408996536850783 0.0159964497695472 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 2.028952245516284e-08 0.0002334823336694 8.206937238409767e-11 8.350760865063851e-09 2.6995663558697725e-07 +Spinocerebellar ataxia 1 11 2.392634668273532 0.016727888038146 2.29126213592233 9.594660194174756 0.4684523610351578 0.5099609720531028 1.6362464027486996 1.23589935457103 0.8565769186147023 0.2999468232045417 0.0173977458976559 0.0065792573185243 0.0246740936940832 0.123579290468326 0.3460963812051635 +Neurodegeneration 20 146 2.316391634908228 0.0205368950767588 27.95631067961165 134.69660194174756 0.269943056894121 0.615157984625689 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"results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c410c685d43d1efb34353780a3ebaaa38395f92c --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,42 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycogen storage disease 0.8619061020424861 2.463771303310487 0.0137483802861282 0.7992864848212884 0.2425543765531179 10 P13473 1 +Gangliosidosis 0.9762117157300018 2.408996536850783 0.0159964497695472 0.8459672106722117 0.2425543765531179 5 P17900,P07602,P16278,P06865 4 +Spinocerebellar ataxia 0.8203879696862073 2.392634668273532 0.016727888038146 0.8586968923225002 0.2425543765531179 11 O14773 1 +Neurodegeneration 0.5440356797277695 2.316391634908228 0.0205368950767588 0.90992226950597 0.2610718445390474 146 O14773,O75503,P05067,O00400,P50897,P06865,Q14108,P54802,Q8IV08,Q15043,Q13510,P02792,Q10713,P07686,Q99720,O95831,Q9NUM4,P04062,P04080,Q96PY6 20 +Mucopolysaccharidosis 0.9701845881620212 2.177010047727986 0.0294798177689559 0.96891647623501 0.3108780782908079 4 P15586,P54802 2 +Niemann-Pick disease 0.9792038027332152 1.8202115311877023 0.0687267977378409 0.9997412118934343 0.5057675439833027 2 P61916 1 +Gaucher disease 0.9702911467617356 1.7849972759685335 0.0742617587296896 0.9998703920312696 0.5057675439833027 2 P07602 1 +Neuronal ceroid lipofuscinosis 0.9940564635958395 1.779019699605612 0.0752365323262425 0.9998853016633752 0.5057675439833027 3 O75503,O14773 2 +Cushing syndrome 0.8296980500527829 1.65598600980578 0.0977246520270878 0.9999934031799412 0.5269678336474858 4 O00170 1 +Lissencephaly 0.6526068178221333 1.6466836615099767 0.0996230842074017 0.9999948331623428 0.5269678336474858 11 P07942,O43505,Q14118 3 +FDA approved drug targets 0.4641542429002328 1.6451340246364077 0.0999421753469369 0.999995041300754 0.5269678336474858 128 Q13423,P28074,P20645,P05067,P02786,P62942,Q9Y2I1,P05556,O75874,P10253,P49721,P33527,P02792,Q9NRF9,Q7L0J3,Q99720,P78559,P06756,O60664,Q96QD8,Q16850,P29317 22 +Osteopetrosis 0.913250148544266 1.558865690413509 0.1190281723407471 0.9999995873381003 0.5564060057720681 2 Q9Y6K9 1 +Epilepsy 0.4521414639640121 1.5247208250536182 0.1273287452165872 0.9999998623811844 0.5564060057720681 69 Q14108,O14773,Q13510,P22466,P04080,O75503,Q9Y4G8,Q8NB90,P11166 9 +Alzheimer disease 0.6922158166112661 1.4895768316792153 0.1363355375648494 0.9999999586927976 0.5564060057720681 7 P05067 1 +Amyotrophic lateral sclerosis 0.5758045271051199 1.4847596192738126 0.1376075122652669 0.9999999651842376 0.5564060057720681 16 Q9UQN3,Q9H9T3,Q99720,Q96PY6,Q99700,Q14203,Q9NUM4 7 +Amyloidosis 0.7002622849075593 1.3536729595280244 0.1758407387092662 0.9999999998191608 0.5568714112009295 5 P05067 1 +Joubert syndrome 0.692760413759351 1.3240363347668516 0.1854909777474507 0.9999999999538762 0.5568714112009295 5 O43924 1 +Disease variant 0.3356385029489425 1.319557296099976 0.1869828685364323 0.9999999999627124 0.5568714112009295 846 Q14126,P42892,O14773,P01130,P15586,O00584,O75503,P61916,Q13423,Q9UBM7,P06280,P05067,O00400,P50897,P02786,P07602,Q9NPF0,P06865,Q4J6C6,Q14108,P04066,Q15643,Q07954,P22466,P54802,Q8IV08,Q9H173,P13473,Q14739,P10619,P10253,P49459,O43772,O00754,P16278,P17900,P53634,Q15043,Q9NX62,P19022,Q02487,Q13510,Q92542,O15118,P28070,Q15126,P02792,Q15904,Q10713,P07686,O00459,P38571,Q15392,Q99720,Q9NUM4,O95831,P10644,P11166,Q9BZH6,P04062,P04080,Q9P273,Q9ULC3,O43505,Q8NB90,P35606,O75844,P29317,Q01105 69 +Leukodystrophy 0.5213433066395501 1.3188358119176689 0.1872240089382435 0.9999999999639736 0.5568714112009295 21 P04350,Q9NR50,O15121,P07602,Q9NUM4 5 +Dystroglycanopathy 0.6952831197484051 1.1456640477444746 0.2519341851812124 0.9999999999999976 0.6494303440226811 4 O43505 1 +Parkinsonism 0.5048091551361241 1.021763545367928 0.3068928270687245 1.0 0.7416576654160844 13 Q14203,P04062,Q15043,O75787 4 +Microphthalmia 0.5599808647853312 1.0078349246116411 0.3135337165669845 1.0 0.7422430841177592 8 O15347,Q9P273 2 +Hereditary nonpolyposis colorectal cancer 0.7462863933452211 0.9085737885569206 0.3635751476354345 1.0 0.7959236718482153 2 P43246 1 +Congenital muscular dystrophy 0.5317434579434208 0.7890136478309926 0.4301040298440233 1.0 0.838002182067936 6 O43505 1 +Primary microcephaly 0.4693029821773519 0.6834771723083383 0.4943053700324094 1.0 0.8753570014660563 9 P35606,Q86XL3 2 +Charcot-Marie-Tooth disease 0.3990421199089224 0.6274169046071504 0.5303859896038055 1.0 0.8991351827416914 24 P54802,P04792,O95831 3 +Ciliopathy 0.3998980000478522 0.564444510221203 0.5724516542127644 1.0 0.8991351827416914 17 O43924,Q96J42,Q96PY6 3 +Premature ovarian failure 0.6410602615212613 0.560310648726042 0.5752675652514898 1.0 0.8991351827416914 3 Q06787 1 +Hereditary spastic paraplegia 0.3934876182338632 0.5123817773755034 0.6083838418691183 1.0 0.9285858639054964 15 O00400,Q92734 2 +Autism 0.4784075281391923 0.4065744729089616 0.6843205490938822 1.0 1.0 4 P06730 1 +Nephronophthisis 0.5508021390374446 0.3074841026371531 0.758474921584303 1.0 1.0 2 O15078 1 +Dystonia 0.3702801727201029 0.2855474285810435 0.7752247733876367 1.0 1.0 8 Q15043,P11166 2 +Myofibrillar myopathy 0.4890077243018544 0.1989802249270968 0.8422782135048639 1.0 1.0 2 O95817 1 +Zellweger syndrome 0.3810939357907194 0.1985610507354667 0.8426061238793199 1.0 1.0 4 Q9Y5Y5,P56589,P40855 3 +Hermansky-Pudlak syndrome 0.4454680534918294 0.1623650064054672 0.8710184259938596 1.0 1.0 3 Q86YV9,O00203 2 +Albinism 0.4454680534918294 0.1623650064054672 0.8710184259938596 1.0 1.0 3 Q86YV9,O00203 2 +Rhizomelic chondrodysplasia punctata 0.4462269756387474 0.1510052475800962 0.8799715763990299 1.0 1.0 2 O15228 1 +Cardiomyopathy 0.3041319335720188 0.1031491239663226 0.9178446176315028 1.0 1.0 29 Q14126,P19022,Q02487 3 +Cockayne syndrome 0.3095662507427306 0.0996593639853287 0.920614762714292 1.0 1.0 2 P18074 1 +Ectodermal dysplasia 0.2770379140110013 0.0877772066085936 0.9300537543161842 1.0 1.0 7 Q02750,Q9H4L7,Q9Y6K9 3 +Cataract 0.2967765313551024 0.0604873654913359 0.9517674783023402 1.0 1.0 30 O00400,P02792,P29317 3 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3d30654bd2a109665dea66829286ce2c1bc942f3 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", 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"HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IKBKB", "IKBKG", "ILF3", "ILK", "IMPA1", "IMPAD1", "IMPDH2", "INF2", "INPPL1", "INTS1", "IPO7", "IRF2BPL", "IRS4", "ISCA2", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LYN", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1B1", "MAN2B1", 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overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 30 52 4.251466172179195 2.123755918126413e-05 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 7.504460491561162e-07 2.8881979120265246e-06 2.2653462709798723e-09 5.751622922929235e-14 1.4247145886502997e-08 +Host cell receptor for virus entry 14 20 3.279768854309471 0.0010389216784474 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 2.12570833522401e-05 0.0011134897140002 1.438337704582012e-07 5.362103925989596e-13 4.934656707696467e-10 +Glycosidase 11 21 3.213545818437098 0.0013110687812205 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 1.1281624002445085e-12 1.9327312747144497e-06 2.041353886158467e-13 1.5339397506791295e-11 7.576932423930797e-09 +Protease 22 90 2.976136189336505 0.0029190519958306 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 2.3440955472614543e-06 1.4076449696608436e-05 2.37461887524904e-06 1.3049944148816e-05 6.84111717042886e-06 +Metalloprotease 8 27 2.7049709587428974 0.0068310361199572 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0116356079020295 0.0028326312129738 0.0024636847742138 0.0004948612164357 0.0004366653435552 +Carboxypeptidase 4 6 2.4891200453805555 0.0128059717634085 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 8.915588878694072e-08 6.712740949068952e-07 2.279759373099411e-07 2.050947898007762e-05 0.0005388274165263 +Transducer 1 11 2.3629162429934296 0.0181317669617691 3.466019417475728 8.91747572815534 -0.1646169358897246 0.5259738353010212 2.4077767773055085 2.0164338021708255 0.961579508666748 0.3124316516206892 0.1006292377029538 0.2778293030066073 0.1367168788611213 0.4819291496478894 0.838996210841251 +Serine protease inhibitor 2 5 2.304285223355618 0.0212066378912147 1.266990291262136 3.5266990291262137 0.2947116096628981 0.478012142815398 1.0341628901681232 1.1133635632531 1.1321039780621556 0.3315824922638006 0.0001774834639225 0.0020655426456597 0.0003080716102714 0.0042908003473226 0.0280386150660574 +Protease inhibitor 3 8 2.267907048153086 0.023334872677827 2.679611650485437 6.827669902912621 -0.1389909380340853 0.4401686430319619 1.73744367643855 1.203518872907143 1.1014803254493444 0.2988298098237953 0.0010512986284106 0.0065792573185243 0.0018000470176383 0.002932051876052 0.0312662716526952 +Heparin-binding 3 8 2.2677820248333846 0.0233424955216616 2.3567961165048543 6.854368932038835 0.2151021415291715 0.4976817002921777 1.5599282492786453 1.096399818915653 1.0317858467489989 0.3203044603738155 0.0187491014912179 0.1201219647894398 0.0265618978442646 0.0033995973847004 0.0075753503172145 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d8306f9defe273d518da1956cf46972b54e3466a --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 100, + "title": "Average number of proteins per term", + "value": 39.37 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ffbbaf6e033a67d11eaf123d1817bb9835779e1e --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8663172d853f5fc17ac5d59b4d9b7370dd5662fe --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,38 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.8587887621085512 4.251466172179195 2.1237559181264132e-05 0.0021215248483268 0.0021237559181265 52 P55899,P13591,P01130,P30825,P20645,Q5KU26,P11717,Q9Y6N7,P02786,P78310,Q9UBG0,Q9Y2I1,P05556,Q99523,Q14108,Q07954,Q14739,P48960,O15118,P10586,P11279,Q99720,Q8WTV0,O43731,P06756,Q9Y624,Q92692,Q15375,P29317,O14786 30 +Host cell receptor for virus entry 0.902131525006449 3.279768854309471 0.0010389216784474 0.0987261911683098 0.0291905199583064 20 P05556,Q14108,P13591,O15118,P01130,P11279,Q8WTV0,Q9Y624,Q92692,P35613,P29317,P02786,P78310,P06756 14 +Glycosidase 0.8796161156937145 3.213545818437098 0.0013110687812205 0.1229514231800182 0.0291905199583064 21 P04066,P54802,Q8IW92,P06280,P10253,Q9BTY2,P07686,O00754,P16278,Q9Y2E5,P06865 11 +Protease 0.5734674464956618 2.9761361893365055 0.0029190519958306 0.2534794050665026 0.0291905199583064 90 P42892,O14773,Q9UIQ6,Q6GQQ9,P28074,Q9HB40,Q99538,O75976,Q4J6C6,Q8TEY7,P78536,P42785,P10619,P53634,Q8TCT8,Q9H3G5,Q9H8M7,P28072,Q7Z2K6,O75844,P55786,O43847 22 +Metalloprotease 0.7296209713064344 2.7049709587428974 0.0068310361199572 0.4961352724671761 0.0487931151425519 27 Q7Z2K6,P42892,P78536,Q9UIQ6,O75844,P55786,O75976,O43847 8 +Carboxypeptidase 0.96556445344609 2.4891200453805555 0.0128059717634085 0.7244172973248086 0.0800373235213036 6 P10619,Q9HB40,O75976,P42785 4 +Transducer 0.8134251042426845 2.3629162429934296 0.0181317669617691 0.8395569434643544 0.100732038676495 11 P02786 1 +Serine protease inhibitor 0.9476241996395464 2.304285223355618 0.0212066378912147 0.8827530529452705 0.1014891109637464 5 P05067,Q06481 2 +Protease inhibitor 0.8626719418025125 2.267907048153086 0.023334872677827 0.9056877483855734 0.1014891109637464 8 Q6YHK3,P05067,Q06481 3 +Heparin-binding 0.8626401963673138 2.2677820248333846 0.0233424955216616 0.9057613304006962 0.1014891109637464 8 O94813,P05067,O14786 3 +Developmental protein 0.4590675042482943 1.8998304160956383 0.0574553779897453 0.9973072751623876 0.2298215119589812 90 Q99598,P48681,Q9Y6N7,P16949,Q99523,Q13685,Q8NB78,Q07954,Q9H0H5,Q92520,O94813,Q9Y4G8,O00115,Q99426,Q9ULC3,P43034,Q8NB90,Q15375,O14786 19 +Aminopeptidase 0.6756946034714542 1.8058009062166975 0.0709494438777715 0.9993633001274536 0.2714724397224491 12 Q9UIQ6 1 +Endonuclease 0.6035549387905711 1.7909734308410383 0.0732975587250612 0.9995056543562996 0.2714724397224491 21 O00584 1 +Nuclease 0.5371286654793412 1.7224732999799444 0.0849838154352051 0.9998610439110266 0.274141340113565 35 O00584,Q8IV08 2 +Muscle protein 0.7446767863920957 1.6421505386055135 0.1005588101814103 0.999975038124318 0.2957612064159127 6 P60660,P06753,Q05682,P67936 4 +Growth factor 0.7418573176755167 1.51771907862155 0.1290852323524387 0.9999990055900256 0.3175080015482206 5 Q9NPF0,P60983 2 +Integrin 0.9201448106733122 1.513399229391334 0.1301782806347704 0.9999991229491464 0.3175080015482206 3 P06756 1 +Thiol protease 0.4986598256471124 1.401398052799825 0.1610950742415493 0.9999999764888192 0.3502066831338029 32 Q6GQQ9,Q99538,P53634,Q9H8M7 4 +Threonine protease 0.8647845468053494 1.3139714016223525 0.188855828416468 0.999999999187534 0.3914248399205962 3 P28072,P28074 2 +Monooxygenase 0.856916161798766 1.285706887533386 0.1985453765973501 0.9999999997557166 0.3970907531947003 3 Q16850 1 +GTPase activation 0.473579541462154 1.2160570756969404 0.2239631804782695 0.9999999999902672 0.4016690985876429 31 Q9H2M9,Q07960,Q0IIM8,Q86X10,Q14C86,Q9Y4G8,P43487,Q9H0H5,O60343,P52565,P50395,P46060,P11274,Q9BXI6,Q8TC07,Q8N6T3,Q4KMP7 17 +Hydrolase 0.4823815836021745 1.213510518791035 0.22493469520908 0.9999999999914132 0.4016690985876429 401 P42892,Q8NHP8,O14773,Q9UIQ6,P15586,O00584,Q9HB40,P06280,Q9UMR5,Q9BTY2,P50897,Q99538,O75976,P06865,P04066,P42785,P54802,Q8IV08,Q8NCC3,P10619,P10253,O00754,P16278,Q9H773,P17900,P53634,Q92820,Q8TCT8,Q9Y2E5,P11117,P34913,Q13510,Q9H3G5,Q8IW92,O00115,P07686,Q9UJ14,P38571,Q7Z2K6,P04062,Q8NB90,O75844 42 +Initiation factor 0.4375276073924626 1.0350227365114777 0.3006582931358494 0.9999999999999996 0.4928824477636876 36 Q14240,O60841,O75821,Q13347,P60842,O43583,Q9NR50,P55010,O00303,P23588,Q9Y262,Q04637,P06730,P55884,P05198,P49770,Q9BY44,O15372,P20042,O75822,Q15056,Q13144 22 +Serine protease 0.5014939354085295 0.9363984644245972 0.3490680682890201 1.0 0.5216830985796526 11 O14773 1 +Tyrosine-protein kinase 0.4946089276866549 0.9355058381389528 0.3495276760483672 1.0 0.5216830985796526 12 Q15375,P29317 2 +Acyltransferase 0.3874708182087429 0.668559157466448 0.5037767334112289 1.0 0.6849098148074824 36 Q86UY6,Q8NCC3 2 +Tumor antigen 0.6726084373143265 0.6474732427231713 0.5173257064384957 1.0 0.689767608584661 2 Q96RS6 1 +Actin capping 0.4471883368045368 0.50897911593964 0.6107668626823277 1.0 0.7540331638053428 7 Q13813,P52907,P47756,O15020,P35241,P47755 6 +Thiol protease inhibitor 0.5695665327785648 0.3716716465795956 0.7101373378402343 1.0 0.8660211437076027 3 P04080 1 +Cytokine 0.4479785969084303 0.3293169504943424 0.7419161333811923 1.0 0.87350028197978 4 P14174,P06744,P43490 3 +Elongation factor 0.3579467219610442 0.3170439649595328 0.7512102425026108 1.0 0.87350028197978 11 P24534,P26641,P63241 3 +Translocase 0.3271393324153437 0.2187118115376693 0.8268745474594874 1.0 0.9396301675675992 25 P08183,Q13423 2 +Rotamase 0.321549520000836 0.1874452708865814 0.8513115305369916 1.0 0.9436513762380322 24 O95302,Q13526 2 +Serine esterase 0.3662306777645597 0.1772963706010175 0.8592756014763359 1.0 0.9436513762380322 4 P10768,Q9Y570,O00154 3 +Protein phosphatase inhibitor 0.3936423054070179 0.1174450017694503 0.9065074245426876 1.0 0.963243961492136 2 Q12972 1 +Guanine-nucleotide releasing factor 0.3039887550121462 0.1066309507471082 0.915081763417529 1.0 0.963243961492136 22 Q02818,P80303,Q9Y4G8 3 +Glycosyltransferase 0.290974226801846 0.0185196366211229 0.9852243124931704 1.0 1.0 36 O43505,P04062 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..442af7f1555fa008b38f0c8390e749f0729c5540 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "G-protein coupled receptor", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Neuropeptide", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP1", "BAZ1B", "BAZ2A", "BCKDHA", "BCKDHB", "BCLAF1", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRMS1L", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CDS2", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CEP290", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK2", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1B", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INF2", "INPPL1", "INTS11", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MATR3", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFN1", "MFN2", "MGA", "MGEA5", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP3", "NCL", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEK1", "NEK9", "NELFA", "NELFCD", "NES", "NET1", "NFS1", "NFYB", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRDC", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD4", "OTUD7B", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDRG1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIGG", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSEN1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD54L2", "RAI1", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO4", "RFC1", "RFC3", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOX1", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", 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4.6402383259117767e-10 9.167209900208325e-14 1.2522888100576335e-09 +Predicted secreted proteins 25 58 3.415725370211551 0.0006361236619305 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 2.9317395220895602e-08 5.261862373040465e-06 3.279383580307499e-07 3.83789412179531e-08 4.81145815799524e-05 +Candidate cardiovascular disease genes 2 10 2.516344777002056 0.0118579120197461 2.563106796116505 9.29368932038835 0.1164468151756199 0.468077533298839 1.894908368881901 1.612649926975264 1.0410221205625372 0.2788935851718957 0.0033107591961438 0.0140700862732742 0.0055856505984271 0.0608575356821196 0.2688137047180795 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..05c1933383f45de5a37f87aed9908484fb91ce74 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3368, + "annotations_size": 22, + "title": "Average number of proteins per term", + "value": 489.90909090909093 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..78ad7a07669236b77fddae9556062410371c55d0 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..30ac5ea55beb78fe8e6bba22d82c390e43918455 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.5217154685155225 5.059872316047299 4.19537322316588e-07 9.229780432429184e-06 9.229821090986936e-06 643 P55899,P42892,Q6UXD5,Q9UIQ6,Q06481,O43493,P01130,Q92859,Q5KU26,P05067,P11717,Q8IXU6,P02786,Q9NPF0,Q9UBG0,O75976,Q9C0H2,Q14108,Q99523,Q8IZA0,O75071,Q07954,P08183,Q8IV08,P13473,Q8NCC3,Q14517,Q14574,P48960,O43772,Q8NC54,P53634,Q8TCT8,O00461,P11117,Q6YHK3,Q9NQX7,Q02487,Q92542,O15118,P11279,O94813,Q13641,Q92896,O60637,Q15904,P51790,Q9UJ14,Q15392,Q7L0J3,P04439,Q99720,Q8WTV0,O43731,Q9NUM4,P43121,P06756,Q7Z2K6,P01889,Q99595,Q5VW38,O60830,O43657,Q9P273,Q9Y624,P27105,Q96QD8,Q86VP1,Q15375,Q16850,O75844,P29317,Q9H2J7,P10321,P08195,O14786,Q14126,Q9NV96,Q9BQE5,P13591,Q6PCB8,O60245,O94898,P30825,Q13423,O15127,Q5BJF2,Q9UBM7,P20645,Q9BXP2,O00400,Q567V2,Q6ZRP7,Q9Y6N7,O95772,Q10472,P78310,O43760,P05556,Q9UEU0,Q93050,Q14739,Q8NBN3,Q8WVI0,Q13740,Q9H2V7,Q15043,Q9NX62,O15260,P19022,P33527,P10586,Q8IYS2,Q8ND04,O60476,O95831,P11166,Q6PK18 118 +CD markers 0.9103590027363264 3.647601018211377 0.0002647002531082 0.0058072487964431 0.0029117027841902 27 P13591,P11717,P02786,Q9NPF0,Q9UBG0,P05556,Q07954,P08183,P13473,P48960,Q13740,Q6YHK3,P19022,P11279,P43121,P06756,Q9Y624,Q92692,P35613,P08195,O14786 21 +Predicted secreted proteins 0.7128976919265153 3.415725370211551 0.0006361236619305 0.0139016408627588 0.0046649068541574 58 Q9UMX5,P13591,O00584,P61916,Q9HB40,Q9BTY2,P05067,P02786,P78310,P80303,P22466,Q08380,Q9UM22,P48960,Q13740,Q02818,Q9Y2E5,Q92520,Q08431,O94813,Q8IW92,P11047,P09429,P07942,O14786 25 +Candidate cardiovascular disease genes 0.8748074915650106 2.516344777002056 0.0118579120197461 0.2308221887743683 0.0434790107390693 10 Q07954,P06865 2 +Human disease related genes 0.3277371463926349 1.6881360839489046 0.0913851091382316 0.8785614145875814 0.2198727857632612 974 P42892,O14773,P01130,P15586,O00584,O75503,P61916,P06280,P05067,P50897,P07602,P06865,Q14108,P04066,P22466,P08183,P54802,Q8IV08,P13473,P10619,Q14574,P10253,O43772,O00754,P16278,P17900,P53634,P11117,Q02487,Q13510,Q92542,O15118,P02792,P07686,P38571,Q15392,P04439,Q99720,Q9NUM4,P01889,O43924,P04062,P07942,Q9P273,O43505,Q8NB90,O75844,P29317,Q01105,P10321,Q14126,Q9BQE5,O94898,Q13423,Q9UBM7,O00170,O00400,Q4J6C6,Q15643,P07099,Q9H173,Q14739,P49459,Q15043,Q9NX62,P19022,P33527,Q9NSV4,Q15126,Q9Y4G8,Q10713,O00459,Q32P28,Q96PU5,O95831,P10644,P11166,Q9BZH6,P04080,Q9ULC3,Q96PY6,Q15056,P35606,O43678,Q92734,P13051,O15347,Q9BXW9,O96000 89 +FDA approved drug targets 0.4641542429002328 1.6451340246364077 0.0999421753469369 0.9013836193046364 0.2198727857632612 128 Q13423,P28074,P20645,P05067,P02786,P62942,Q9Y2I1,P05556,O75874,P10253,P49721,P33527,P02792,Q9NRF9,Q7L0J3,Q99720,P78559,P06756,O60664,Q96QD8,Q16850,P29317 22 +Disease related genes 0.3239245728628317 1.4806406658902451 0.1387023528151061 0.9625569050918722 0.2774047056302122 1083 P42892,O14773,P01130,P15586,O00584,O75503,P61916,P06280,P05067,P50897,P02786,P07602,Q9NPF0,P06865,Q14108,Q99523,P04066,Q07954,P22466,P08183,P54802,Q8IV08,P13473,P10619,Q14574,P10253,O43772,O00754,P16278,P17900,P53634,P11117,Q02487,Q13510,Q92542,O15118,P02792,Q15904,P07686,P38571,Q15392,P04439,Q99720,Q9NUM4,P01889,O43924,P04062,P07942,Q9P273,O43505,Q8NB90,O75844,P29317,Q01105,P10321,Q14126,O94898,Q13423,Q9UBM7,O00170,O00400,Q4J6C6,Q15643,P07099,Q9H173,Q14739,P49459,Q15043,Q9NX62,P33527,Q9NSV4,P10586,P28070,Q15126,Q9Y4G8,Q10713,O00459,Q32P28,Q96PU5,O95831,P10644,P11166,Q9BZH6,P04080,Q9ULC3,Q96PY6,Q15056,P35606,O43678,Q92734,P13051,O15347,Q9BXW9,P78318,P67870,Q14118,Q8N6R0,Q9Y6K9,Q15059,P78536,P51798,O75874,Q0IIM8,Q9H0U9,Q9NR50,Q9HC07,Q9H061,P49768 108 +RAS pathway related proteins 0.4813930048929936 1.1811032073329188 0.2375617259672768 0.9974384480380576 0.4020275362523147 26 P28482,P63000,Q02750,Q9UBI6,Q06124,P62993,Q9Y6K9,P36507,O00459,P29317,Q13177,Q04206,P27361,P11233 14 +Enzymes 0.303937276679062 0.7750895428332765 0.4382867503176302 0.999996914520262 0.6428205671325243 939 P42892,O14773,Q9UIQ6,P15586,O00584,Q13423,Q9HB40,Q9UBM7,P06280,Q86UY6,Q9BTY2,O95302,P50897,Q6ZRP7,P02786,Q99538,Q10472,O75976,P06865,Q4J6C6,P04066,P42785,Q8NB78,P07099,P08183,P54802,Q8IV08,Q14739,Q8NCC3,P10619,P10253,P49459,O00754,P16278,Q9H773,P49721,P53634,Q92820,Q8TCT8,Q9Y2E5,Q9UHG3,P11117,Q9NX62,P34913,P33527,Q13510,Q9H3G5,Q9H8M7,P10586,P28070,Q15126,P28072,O00115,P07686,Q9UJ14,P38571,Q15392,Q10713,Q32P28,Q96PU5,Q7Z2K6,P04062,P35790,Q8NB90,Q15375,Q16850,O75844,P29317,P55786 69 +Metabolic proteins 0.3038858865330531 0.6603330212346288 0.5090401439107128 0.9999998404078132 0.6587578332962166 914 O14773,P01130,P15586,P30825,Q13423,Q7LGA3,Q9UBM7,P06280,Q9UMR5,Q86UY6,Q9BTY2,O95302,O00400,P50897,P02786,Q99538,P07602,Q10472,P06865,P04066,P07099,P08183,P54802,Q8IV08,Q93050,Q14739,Q8NCC3,P10619,P10253,P49459,O43772,O00754,P16278,Q9H773,P17900,P53634,Q92820,Q9UHG3,Q9Y2E5,Q15043,P11117,Q9NX62,P34913,P33527,Q13510,O15118,P10586,Q15126,Q15904,Q10713,P07686,Q9UJ14,P38571,Q15392,O00459,Q96PU5,Q8WTV0,O60476,P10644,P11166,O43924,Q9Y678,P04062,P35790,O43505,Q96PY6,Q96QD8,P35606,Q15375,Q16850,O60684,O75844,P29317,Q9H2J7,P55786,P08195 76 +Transporters 0.4258796403798011 0.4690615328048268 0.6390256538558154 0.9999999998161432 0.7810313547126633 407 Q9NV96,Q6PCB8,P30825,O00560,P61916,O15127,Q5BJF2,Q14118,P20645,Q9BXP2,P05067,P11717,O00400,Q8IXU6,P02786,Q8NE01,P07602,P78310,P62942,Q8IY95,Q9C0H2,Q14108,Q99523,P05556,Q9BSK2,Q9GZM5,P78536,Q07954,Q9UEU0,P08183,Q13438,P51798,Q93050,P13473,Q9HC07,Q9NUQ8,P48960,O43772,Q9H061,Q13740,Q9H2V7,Q8TCT8,Q15043,O15260,P33527,O15118,P11279,O60637,Q15904,P04439,Q99720,Q8WTV0,Q9C0E2,Q9NUM4,Q08722,P06756,P11166,Q5VW38,P04080,P27105,Q96QD8,P35613,O60684,O75844,Q96L92,Q9H2J7,P08195,O14786 68 +Potential drug targets 0.3821844529543312 0.3889389454296619 0.6973213116398589 0.999999999996184 0.8074246766356261 509 P42892,O14773,P15586,O00584,P61916,Q9UBM7,P06280,O00400,P50897,P07602,P06865,Q4J6C6,Q14108,Q99523,P04066,Q07954,P07099,P54802,Q8IV08,P13473,Q14739,P10619,P49459,O43772,O00754,P16278,P53634,Q15043,P11117,Q9NX62,Q13510,O15118,P10586,P28070,Q15126,Q15904,Q10713,P07686,Q32P28,P38571,Q15392,Q96PU5,P04439,Q9NUM4,P11166,P04062,P04080,Q8NB90,O75844 49 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fa74e0f06584162349eb7c8470d29c8ab3baf326 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "G-protein coupled receptors", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAM17", "ADAR", "ADD1", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP3", "ARFGEF2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC10", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD3", "BRD4", "BRD7", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BRPF1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf98", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf131", "C1orf35", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CDYL", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPV", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD2", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD3", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMB", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID4", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAT4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAGED2", "MAGI3", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MAN2B2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED24", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRFAP1", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK1", "NEK9", "NELFA", "NELFCD", "NEMF", "NENF", "NEO1", "NES", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NGDN", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB39A", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPOUT1", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", 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0.4161874156663988 1.7430278696515865e-05 5.902662250610832e-05 6.180274238890361e-05 2.1946873920722807e-09 9.896198882394916e-05 +Lysosomes 6 15 2.441019720889692 0.0146458549539574 3.070388349514563 12.849514563106796 0.5262633691996788 0.494935559010686 2.4420262247147067 1.0913048915370858 0.8749364663493571 0.309114949195179 0.1439609493286736 0.0892490045576324 0.0007914120786236 0.0010078083449561 1.8924379158190217e-05 +Cell Junctions 11 59 2.364929743829054 0.0180334915699451 10.20388349514563 48.779126213592235 0.0528444018541478 0.6962606359612301 5.43694521473042 8.010142309536178 0.7104622417864562 0.2975972437396429 0.5025736040867183 0.2680094392952094 0.6036114505952551 0.0046387100568416 0.0783036293069947 +Microtubules 17 48 2.2593852972491337 0.0238594281752628 11.762135922330096 51.536407766990294 0.1467824701124027 0.6383504938877967 6.107191630577272 6.9907105288235005 0.8576674618245522 0.3225755572425843 1.0 1.0 1.0 0.0650200504619928 0.0021792503980802 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0000000000000000000000000000000000000000..1f9c3671bf802d15c22006ffa65fa0d6e0be7380 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C149/C149_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a1938654a2d8f641774d853020c57fccaa27b245 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.6220577100516712 2.8168845786141774 0.0048491948856999 0.1482078033187662 0.0818396226846043 195 O43493,O94898,O15127,Q9HB40,Q92859,Q5KU26,O95302,P05067,P11717,P50897,Q8IXU6,Q6ZRP7,O43760,Q99523,Q8IZA0,O75071,P80303,Q15643,P22466,Q9UEU0,Q93050,Q8NBN3,A9UHW6,P16278,Q8NC54,Q02818,Q9H2V7,O00461,Q15043,Q9NX62,O15260,Q92520,P10586,Q92896,O60637,Q8IYS2,P04439,O60476,Q9Y678,Q5VW38,O95456,P29317 42 +Lysosomes 0.7756313136622461 2.4410197208896913 0.0146458549539574 0.3854637878448655 0.1189554183790618 15 Q8N122,O15400,P02786,Q8WTV0,Q8IY95,Q9NUM4 6 +Cell Junctions 0.5672820460416317 2.364929743829054 0.0180334915699451 0.4514827390343776 0.1189554183790618 59 Q14126,P19022,P33527,O60245,O43657,Q9Y624,Q8N3F8,Q5KU26,Q14574,P29317,P78310 11 +Microtubules 0.568100964413294 2.2593852972491337 0.0238594281752628 0.5492787746599481 0.1189554183790618 48 Q13685,P04350,Q9BZH6,Q9NSV4,Q6GQQ9,O60830,O75347,Q9BUF5,Q9Y624,P07437,Q13564,Q9HC35,Q02818,Q14203,P55209,Q9Y2I1,Q13409 17 +Endosomes 0.7155352844410174 2.051307688262014 0.0402369922402934 0.7421232272495848 0.1475356382144092 13 Q13596,O60749,O14964,P02786,Q8IY95,Q9NUM4,P09496 7 +Focal adhesion sites 0.5588672636967773 1.7006167491383717 0.0890149769446917 0.9538819619723666 0.2858368415614833 27 P08183,P06756 2 +Vesicles 0.4840762480701625 1.1063853054125334 0.2685597830189055 0.9999670464979776 0.5908315226415921 326 Q06481,O15127,Q9UMR5,Q5KU26,O95302,P05067,P11717,P50897,O00400,O95772,Q99538,P07602,P06865,Q9Y2I1,P04066,P42785,Q07954,P22466,Q9UEU0,Q93050,P13473,Q8NCC3,P10619,P10253,P49459,O00754,P16278,Q13740,P17900,P53634,Q96ED9,Q8TCT8,Q9H2V7,O94992,O15118,Q8IW92,P67809,P51790,Q9UJ14,P38571,Q32P28,Q8WTV0,Q8N122,P27105,P35613,Q92734,Q96L92,Q9H2J7,Q13137 49 +Centriolar satellite 0.4435861289356085 1.0214609884296644 0.3070360829371399 0.9999944607559134 0.596011219819154 32 O60271,Q9P260,O43169,Q7Z4H7,Q8N3F8,Q96PY6,Q86UY6,Q15154,P41208 9 +Mitotic spindle 0.4566920403953783 0.9375531465074362 0.3484740992811654 0.9999992759882488 0.5973670840456213 21 P04350,Q6GQQ9,Q9BUF5,P07437,Q9NWV4,Q14203 6 +Lipid droplets 0.3746038134100979 0.3484534001806309 0.7274997046954748 1.0 0.8891663057389135 10 Q01105,Q7L5N7 2 +Cytokinetic bridge 0.3180396289071264 0.1831266595648451 0.8546986381637443 1.0 1.0 28 P04350,Q6GQQ9,Q9BUF5,P07437,P61201,Q6IBW4,Q14203,Q9Y2I1 8 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..320017b9672d71c33942ecdfcdf3b05541a37491 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", 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"CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIB1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK2", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT3", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COTL1", "COX15", "COX4I1", "COX5B", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCK", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGT7", "GHITM", "GID4", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA4", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOT1", "GPAA1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM2B", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRCH2", "LRIG2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAGED2", "MAGI3", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN1B1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCM8", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED23", "MED25", "MED4", "MESD", "METAP2", "METTL13", "METTL14", "METTL16", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGA", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRFAP1", "MRGBP", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS14", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK1", "NELFA", "NELFCD", "NEMF", "NEO1", "NES", "NET1", "NF2", "NFATC2IP", "NFS1", "NFU1", "NFYB", "NGDN", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F2", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OTUD4", "OTUD7B", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PBXIP1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCF11", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3F", "POLRMT", "POM121C", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSEN1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "R3HCC1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RFT1", "RHBDD2", "RHOT2", "RIC8A", "RIF1", "RING1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF14", "RNF20", "RNF213", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROBO1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC5A6", "SLC6A15", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPOPL", "SPPL2A", "SPR", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM2", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK3", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STRN4", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TATDN1", "TAX1BP1", "TBC1D1", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM109", "TMEM126A", "TMEM131", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TXLNA", "TXNDC15", "TXNDC5", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBLCP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR77", "WDR82", "WDR89", "WIPI2", "WIZ", "WNK1", "WRNIP1", "XAB2", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBTB33", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYM4", "ZMYND8", "ZNF281", "ZNF292", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAMP", "ABCB1", "ABCC1", "ALCAM", "APLP2", "APP", "ATP6V0A1", "BSG", "C1orf123", "C5orf15", "CALCOCO2", "CDH2", "CETN2", "CLCN3", "CLTA", "COLEC12", "COPG1", "COPS2", "CTSA", "CTSC", "CXADR", "CYB5B", "DCTN1", "DIAPH3", "DSC3", "DSG2", "DYNC1I2", "EFCAB14", "EML4", "EPHA2", "F11R", "FAM3C", "FKBP9", "FUCA1", "GAA", "GAL", "GGT7", "GLB1", "GLB1L2", "GLG1", "GM2A", "GOLIM4", "GPR107", "HAUS6", "HEXA", "HEXIM1", "HGS", "HLA-A", "HOOK2", "IGF2R", "IMPAD1", "ITGAV", "KIAA0319L", "KIAA1468", "KIAA2013", "LAMP2", "LGMN", "LIPA", "LPCAT2", "LRIG2", "LRP1", "MAN1A2", "MAN2B1", "MICALL1", "MIF4GD", "NAA40", "NAE1", "NAP1L1", "NCAPH2", "NEK1", "NEO1", "NISCH", "NPC1", "NUCB1", "NUCB2", "OTUD7B", "P3H1", "PCDH7", "PCM1", "PLA2G15", "PPT1", "PPT2", "PRCP", "PSAP", "PSMG1", "PTPRF", "QSOX2", "RPTOR", "SCAMP2", "SCARB1", "SCPEP1", "SET", "SLC33A1", "SLC35F2", "SLC39A14", "SLC6A15", "SNX1", "SNX2", "SNX27", "SORT1", "SPAG9", "SPNS1", "SPPL2A", "STARD3NL", "STOM", "STX7", "SURF4", "SYNGR2", "TBCA", "TFG", "TFRC", "TGOLN2", "TIMM17B", "TMEM106B", "TMEM192", "TMEM87A", "TRIP11", "TSPAN3", "TSPAN6", "TUBB", "TUBB4A", "TUBB6", "UBE2A", "VTI1B", "WDR11", "YBX1"]} \ No newline at end of file