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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Transport of small molecules 0.5536729726302105 4.950438520259898 7.404644632855775e-07 0.0010390722815055 0.0008621857677581 164 P04920,Q9BU23,P16615,Q8TB61,Q9C0H2,P21796,P53985,P09601,P23634,O00400,Q8IYU8,P45880,Q8WTV0,P30519,P28072,Q8NEW0,Q9H0U3,P62191,P30825,P61289,P33527,P20020,P40855,Q10713,Q15904,P10644,Q9UNM6,P49721,P12236,Q9UBV2,Q93050,O15118,Q70HW3,P27105,Q15043,P61421,O95202,P05023,Q6PCB8,Q9UBX3,Q9BPX6,P61916,P02792,Q96PU5,Q9BUN8,Q9H2J7,Q9H300,Q99797,Q9NP58,P35613,Q8WWI5,Q9HD20,Q9Y487,P20618,Q96QD8,Q9GZP9,Q9Y277 57
Protein localization 0.6690229842356852 4.851035618336486 1.2281848543554102e-06 0.0017228867182093 0.0008621857677581 76 O60830,Q99595,O15228,O75746,Q5JRX3,Q9NS69,P21796,P50402,P09601,Q9UJS0,P12235,O15254,P51553,O14925,Q9BY49,O75431,Q8N4H5,Q9Y5J9,P40855,O43615,Q13190,Q10713,Q9Y512,P51648,P12236,Q9Y5J7,Q5T8D3,Q8NBU5,Q15388,Q3ZCQ8,P56589,Q15067,P46379,O43808,O00116,O75381,Q9Y5Y5,Q13505,Q9NX63,Q9NR77,O96008,O75521,O43681 43
The citric acid tca cycle and respiratory electron transport 0.5648426196984888 4.350825304071351 1.3562607867889652e-05 0.0188618764248956 0.002282367571676 95 O95299,O43676,O43708,Q86Y39,P21796,P00403,Q9UDW1,P53985,O43819,O75964,Q9NX14,O75306,O75880,P20674,Q15118,P00846,O14949,Q9P0J0,P03886,P22695,Q13423,Q9NPL8,P56385,P24539,Q9H9P8,P13073,Q16134,O95563,P35613,P21912,Q6P587,O95168,O96000 33
Sphingolipid metabolism 0.8040396339160187 4.051878132236066 5.08081293855156e-05 0.0688514230784076 0.0023011165695892 27 P17900,Q06136,P27544,P16278,O15121,O95470,Q13510,Q9NZJ7,P51648,P07602,O15269,Q96G23,P10619,P06865,Q8NBJ7,P04062 16
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.628152029059122 3.9454093868548417 7.966375406920356e-05 0.1058237414814959 0.002796197767829 62 O95299,O43676,Q86Y39,P00403,Q9UDW1,O75964,O43819,Q9NX14,O75306,O75880,P20674,P00846,O14949,Q9P0J0,Q9NPL8,P03886,P56385,P22695,P24539,P13073,Q16134,P21912,O95168,O96000 24
Mitochondrial protein import 0.7271750208882027 3.918844957352691 8.897432229426627e-05 0.1174373543877895 0.0028390897386625 34 O60830,Q99595,Q9NS69,O75746,Q5JRX3,P21796,Q9UJS0,P12235,P51553,O14925,Q8N4H5,Q9Y5J9,O43615,Q10713,Q9Y512,P12236,Q9Y5J7,Q15388,Q3ZCQ8,Q13505,Q9NX63,O96008 22
Slc mediated transmembrane transport 0.7626250818904882 3.8401024876496375 0.0001229829580804 0.1585920771762511 0.0033502432018406 28 P04920,Q9H936,Q8TB61,P53985,O00400,P12235,Q8NEW0,P30825,P12236,Q70HW3,Q15043,P11166,Q6PCB8,Q9UBX3,Q9H2J7,P35613,Q8WWI5,P08195,Q96QD8 19
Respiratory electron transport 0.6200696502221132 3.639479810220817 0.0002731893548701 0.3186030540196217 0.0054022232991233 52 O95299,O43676,Q86Y39,P00403,Q9UDW1,O43819,Q9NX14,O75306,O75880,P20674,O14949,Q9P0J0,Q9NPL8,P03886,P22695,P13073,Q16134,P21912,O95168,O96000 20
Metabolism of lipids 0.443544374419276 3.476537348748411 0.0005079334771889 0.5099852453550927 0.0088041802712745 191 O75845,P27544,O95772,Q9NPJ6,O95864,O95470,P50416,P50897,O15269,Q15800,P07602,Q15185,Q9H7Z7,P23786,Q9NZ01,O15254,Q9P035,P04062,Q9BY49,P16278,Q14534,P33527,Q13510,Q53GQ0,Q9NPH0,Q8IV08,P51648,Q10713,P04035,Q9BWD1,Q86UL3,Q8IY17,Q16850,Q5T8D3,Q8NBJ7,Q15392,Q16836,Q9UMR5,Q8NCC3,Q9BVG9,Q9UG56,O00459,Q96G23,P10619,P37268,P06865,Q15165,Q15067,P38435,Q06136,P17900,O00116,Q96N66,Q9NZJ7,Q8WWI5,P42126,Q14849,O15121,P11310,O43681 60
Ion channel transport 0.6821071111591326 3.214973402502839 0.0013045660918022 0.8400360116099881 0.0165009981341479 26 P61421,P20020,Q9C0H2,P05023,Q15904,P23634,Q9HD20,Q9Y487,Q96PU5,Q93050,P27105 11
Glycosphingolipid metabolism 0.7983412277098816 3.0647257752501207 0.0021786966086483 0.953216611377898 0.0250728691683791 15 P17900,P16278,Q13510,Q9NZJ7,P07602,P10619,P06865,Q8NBJ7,P04062 9
Cristae formation 0.6994418146417825 3.0301641629056073 0.002444208463695 0.96780259391919 0.0276747474437734 20 P56385,Q13505,Q9NX63,Q6UXV4,Q9BUR5,Q16891,Q9Y512,P24539,P00846,Q9NVH1,Q5XKP0,O75964 12
Sphingolipid de novo biosynthesis 0.8528500883563137 3.0250588889154137 0.0024858472102025 0.9696353036561324 0.0279210358649945 12 P27544,O95470,P51648,O15269,Q96G23,O15121 6
Glycosaminoglycan metabolism 0.8159736340692286 2.9842880192942656 0.002842390766752 0.9816182875058962 0.0314229656418891 13 P15586,P16278,Q7LGA3,Q8TB61,P54802,Q8NCH0,O43505,P06865 8
Mitochondrial calcium ion transport 0.7420005550067537 2.9463072331087683 0.0032159279861361 0.9891374992037832 0.0350012627328303 17 Q9UJZ1,Q8NE86,Q9H300,P35232,O95202,P21796,Q10713,Q8IYU8,Q9BPX6,Q8WWC4,P45880,Q99623,Q9Y277 13
Mitochondrial biogenesis 0.592936916808432 2.8814230325498964 0.0039588390929632 0.9961866272283671 0.0424290846299266 33 O75431,P56385,Q13505,Q9NX63,P54619,Q6UXV4,Q9BUR5,Q00059,Q16891,Q9Y512,P24539,P00846,Q9NVH1,Q5XKP0,P48735,O75964 16
Complex i biogenesis 0.5985536003170495 2.8359040970914604 0.0045696165510122 0.9983882668484856 0.0461564146591457 31 O95299,Q9NX14,O75306,O43678,O43676,Q9NPL8,Q86Y39,P03886,Q9Y6M9,Q9BU61,Q9P032,Q9P0J0,O95168,O96000,O75380,O95139 16
Organelle biogenesis and maintenance 0.4335280814916809 2.8154415020006325 0.0048710264049893 0.9989464940135926 0.0485029863305325 96 O95684,Q6UXV4,Q9BUR5,O43924,O75964,Q9H6D7,P04350,Q10713,Q9BUF5,Q9Y512,P00846,Q13561,P56385,P07437,O75935,P24539,Q9BVA1,A6NIH7,Q13505,Q9NX63,Q92973,O94927,Q13885,Q5XKP0,P41208 25
Glycerophospholipid biosynthesis 0.5829494715824076 2.759293490535639 0.0057926485543438 0.9997131426163032 0.0549518822317479 32 Q9NP80,P40939,O15228,O75131,Q7L5N7,P35790,Q92604,Q86UL3,Q9NPH0,Q8IV08,Q8WUK0,O95674,Q53H12,Q8NF37,Q8NCC3,Q99829,Q9BVG9,Q9UG56,Q96N66,P43304,Q8WWI5,Q9BZF1 22
Mitophagy 0.7891572072851641 2.7071194667650276 0.0067869828997246 0.9999296063412082 0.0606937833835251 12 Q8IWA4,Q9NS69,Q8N4H5,P21796,Q15388 5
Selective autophagy 0.5776045666749591 2.675659170024129 0.0074582448711613 0.9999727544428996 0.0654460987444405 31 Q8IWA4,Q9NS69,Q8N4H5,P21796,P04350,Q9BUF5,Q9BVA1,Q13885,P08670,Q15388 10
Downregulation of erbb4 signaling 0.935828877005348 2.6576011784745956 0.0078698963400813 0.9999847821654058 0.067846259516303 2 P46934 1
Peptide ligand binding receptors 0.8878130846858456 2.6436049733969553 0.0082028325808287 0.9999905005052732 0.0693781743583348 7 P42892,P04083,P22466,Q9NZJ7 4
Class a 1 rhodopsin like receptors 0.8878130846858456 2.6436049733969553 0.0082028325808287 0.9999905005052732 0.0693781743583348 7 P42892,P04083,P22466,Q9NZJ7 4
Hs gag degradation 0.9304812834224606 2.6344470264543873 0.0084274453009975 0.9999930881444564 0.0704293643011941 2 P16278 1
Transport of bile salts and organic acids metal ions and amine compounds 0.8827729842308836 2.621330784463592 0.0087587231739212 0.9999956763818484 0.0723367490363848 7 Q8NEW0,Q9H2J7,Q6PCB8,P35613,Q8WWI5,Q15043 6
Nrif signals cell death from the nucleus 0.9200831847890684 2.589259965582199 0.0096182452269304 0.9999987209311654 0.0789708555474289 2 P49768 1
Transport of inorganic cations anions and amino acids oligopeptides 0.7632067690269618 2.573885795370823 0.0100563461430374 0.9999993127604312 0.0820878487489798 12 P04920,Q9H2J7,P30825,Q9H936,P08195,Q9UBX3,Q96QD8,Q70HW3 8
Gpcr ligand binding 0.8057586928402845 2.550739032363459 0.0107494782784232 0.9999997429436568 0.0872385404792265 10 P42892,P04083,P22466,Q9NZJ7 4
Metal ion slc transporters 0.9058229352347028 2.52693434077408 0.011506301214136 0.999999912226598 0.0912703214951812 2 Q8NEW0 1
Zinc transporters 0.9058229352347028 2.52693434077408 0.011506301214136 0.999999912226598 0.0912703214951812 2 Q8NEW0 1
Ire1alpha activates chaperones 0.5767488176801102 2.470741206969454 0.0134833354745418 0.999999994720243 0.1034459180669767 26 P61421,O43731,Q9Y5M8,P43307,O95070,O14773 6
Class i peroxisomal membrane protein import 0.7413438573922221 2.459914071138373 0.0138970284545079 0.9999999970700272 0.1060403692941799 12 O75381,Q9Y5Y5,P40855,P51648,Q9NR77,P56589,Q5T8D3,Q8NBU5 8
Pink1 prkn mediated mitophagy 0.8045415871058559 2.449286370743613 0.0143139592666299 0.9999999983819088 0.1068978660124916 9 Q8IWA4,Q9NS69,Q8N4H5,P21796,Q15388 5
The activation of arylsulfatases 0.8865121806298278 2.441881513757592 0.0146109411181618 0.9999999989401092 0.1079671648942065 2 Q8NBJ7 1
Phospholipid metabolism 0.4868055305148908 2.4180224618703643 0.0156051134873609 0.9999999997430988 0.1147098394568311 51 Q9NP80,O15228,Q7L5N7,Q9BTU6,Q92604,Q8IY17,Q86UL3,Q9NPH0,Q10713,Q8IV08,Q8WUK0,Q9NTJ5,Q53H12,Q8NF37,Q8NCC3,Q9BVG9,Q9UG56,O00459,Q96N66,P43304,Q8WWI5,Q9BZF1 22
Asparagine n linked glycosylation 0.3872769668232211 2.408674927798038 0.0160105515429311 0.999999999855928 0.1170771581576842 126 Q9Y3B3,Q9NYU1,Q9BT22,Q96AA3,O75340,P24390,P46977,Q9BV10,O60476,P16278,Q9H0U3,O43731,P62191,Q9BUF5,P04350,Q12907,Q13190,Q9UBV2,Q9H3H5,Q13561,O75935,Q15363,P49755,Q9BVA1,P53634,Q9UJW0,Q86YN1,P10619,Q9BUN8,Q96PC5,Q13885,O95249,Q9GZP9 33
Transport and synthesis of paps 0.873737373737377 2.385203968831598 0.0170696542771904 0.9999999999682364 0.1222744622713028 2 Q8TB61 1
Ion transport by p type atpases 0.809019472431879 2.377872571485149 0.0174128422265442 0.9999999999805465 0.12313442713523 8 Q9HD20,P23634,P20020,P05023 4
Processing of smdt1 0.7256339388119134 2.3770269253662697 0.0174528141025005 0.9999999999816264 0.12313442713523 12 Q9UJZ1,Q8NE86,Q9H300,P35232,Q10713,Q8IYU8,Q9BPX6,Q8WWC4,Q99623 9
Copi dependent golgi to er retrograde traffic 0.4816571742225252 2.337553454567037 0.0194104248986761 0.9999999999988828 0.1342474707277898 48 Q9Y3B3,Q9P2W9,Q12981,Q86Y91,O15260,O43731,Q9BUF5,P04350,Q15363,Q9BVA1,Q13885,P24390,Q6NUQ1 13
Plasma lipoprotein remodeling 0.8624480095068333 2.334845465730561 0.0195514950878734 0.9999999999990872 0.1345602897224232 2 Q9BU23 1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7121169210558668 2.305038463420364 0.0211644193440327 0.9999999999999096 0.1424361370146424 12 P50402,P51648,P09601,P46379,O43681 5
Peptide hormone metabolism 0.6465607978774492 2.2883100060706205 0.0221194742197285 0.999999999999977 0.1452472275173032 16 Q15005,P67812,Q8NEW0 3
Organic anion transporters 0.8452168746286444 2.2574958479390244 0.0239771086420224 0.9999999999999984 0.1530175478790884 2 Q9UBX3 1
Intra golgi and retrograde golgi to er traffic 0.380981671494219 2.2363641061023043 0.0253279303463356 0.9999999999999998 0.1584008110148121 101 Q9Y3B3,Q12981,P24390,Q6NUQ1,Q9P2W9,Q86Y91,O60476,O15260,O43731,Q9BUF5,P04350,Q13190,Q13561,O43493,O75935,Q15363,P49755,Q9BVA1,O00461,Q10472,Q13885,Q8TBA6,O95249 23
Signalling to ras 0.8229352346999417 2.156616546874094 0.0310355541783562 1.0 0.1893105474096813 2 P11233 1
Heparan sulfate heparin hs gag metabolism 0.9303170835618266 2.1416534168788472 0.0322213818596204 1.0 0.1924750632164083 4 P16278,Q7LGA3 2
Formation of atp by chemiosmotic coupling 0.7207323991274983 2.1315544744129196 0.0330434896989395 1.0 0.1942736276929376 10 O75964,P00846 2
Ras processing 0.924053086864359 2.116768367238917 0.0342795112618552 1.0 0.1988778256679535 4 O43924 1
Cholesterol biosynthesis 0.6045442836491508 2.112825478241498 0.0346157081167572 1.0 0.2000018691190421 17 O75845,Q16850,Q14534,P04035,Q15800,P37268,Q15392 7
Recruitment of numa to mitotic centrosomes 0.4829440004072541 2.0914334557514054 0.0364892257648892 1.0 0.2082555811947336 36 O95684,Q13561,P07437,Q9H6D7,P04350,Q9BUF5,O94927,Q9BVA1,Q13885,P41208 10
Autophagy 0.4505091460820367 2.0713237273948515 0.038328553359596 1.0 0.2143955733739954 52 Q8IWA4,Q9NS69,Q8N4H5,Q15388,Q15382,P21796,P04350,Q9BUF5,Q9BVA1,Q13885,P08670,P13473 12
Activation of nmda receptors and postsynaptic events 0.5338010123760989 2.059200647685356 0.039475021163756 1.0 0.2199322607694977 23 P07196,P54619,Q9BUF5,P04350,P10644,Q14168,Q9BVA1,Q13885,P52292,Q15418 10
Peroxisomal lipid metabolism 0.6865648798904975 2.056206934400764 0.0397625741681371 1.0 0.2206587119844447 11 Q9BY49,P51648,Q15067,Q5T8D3,O15254,O75521 6
Basigin interactions 0.736682229033352 2.0333662410593796 0.0420155353693225 1.0 0.2255938797453091 8 P53985,P08195,P35613 3
O linked glycosylation of mucins 0.9026429034857072 2.032732616190768 0.042079544183768 1.0 0.2255938797453091 3 Q10472 1
Iron uptake and transport 0.5632954465743103 2.0243124246048345 0.0429380160439982 1.0 0.2266769201419668 19 P30519,Q15904,P09601,Q9Y487,P02792,Q93050 6
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7159675346030905 2.0181143212596124 0.0435793565000821 1.0 0.2274550800227336 9 Q9NR77,P04035 2
Acyl chain remodelling of pg 0.7917409387997647 2.0138123258677765 0.0440292411371674 1.0 0.228567864545774 2 Q92604 1
Transport of vitamins nucleosides and related molecules 0.7146258275345427 2.0114149772154315 0.0442816426691181 1.0 0.228567864545774 9 P12235,Q8TB61,O00400,P12236 4
Cell surface interactions at the vascular wall 0.5469348166140704 2.0109143430019984 0.0443345050926173 1.0 0.228567864545774 20 Q9UPY5,P35613,P53985,Q08722,P08195,O00459 6
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8959525843381078 2.0057191177446865 0.0448862243233418 1.0 0.228567864545774 3 P67812 1
Synthesis secretion and deacylation of ghrelin 0.8959525843381078 2.0057191177446865 0.0448862243233418 1.0 0.228567864545774 3 P67812 1
Heme degradation 0.85416731976453 1.9945529688747103 0.0460916574200727 1.0 0.2311167393492217 5 P09601,P30519 2
Pyruvate metabolism and citric acid tca cycle 0.4735186666092942 1.9825713969275236 0.0474153249819033 1.0 0.23487465524656 35 Q9H9P8,P51553,O43708,Q13423,O95563,P21796,P35613,P53985,P21912,Q15118,Q6P587,P48735 12
Activated notch1 transmits signal to the nucleus 0.8900118906064183 1.9804783178348169 0.0476498073304263 1.0 0.23487465524656 4 Q96J02,P49768,Q92542 3
Nuclear envelope ne reassembly 0.4444679709404828 1.975733258670716 0.0481849959822759 1.0 0.236544525731173 48 Q7Z3B4,Q86XL3,Q8NFH5,Q92973,P42166,Q9BUF5,P50402,P04350,Q8N1F7,Q9BVA1,Q9BTX1,Q13885,P02545,P42167 14
Mucopolysaccharidoses 0.8852897473997032 1.9625330468558893 0.0497004570497909 1.0 0.2414513553560779 3 P54802,P16278 2
Proton coupled monocarboxylate transport 0.8817236255572068 1.948053874581874 0.0514085171312732 1.0 0.2488194533789601 3 Q6PCB8,P35613 2
Notch4 activation and transmission of signal to the nucleus 0.881228946724269 1.946043976176264 0.0516494573417807 1.0 0.2488194533789601 3 P49768 1
Regulation of lipid metabolism by pparalpha 0.5377052477102435 1.9452177600041924 0.0517487752041712 1.0 0.2488194533789601 20 Q9NPJ6,P50416,P04035,P23786,P37268,Q15067,P11310 7
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5368382835170796 1.939022716114582 0.0524985721634947 1.0 0.2489383016237663 20 Q02818,O43493,O43852,Q06481,O76024,Q07065 6
Metabolism of porphyrins 0.664369777875854 1.9379044323309196 0.0526348831212415 1.0 0.2489383016237663 11 P33527,P30519,P09601 3
Incretin synthesis secretion and inactivation 0.8790807409962054 1.9363449744584624 0.0528254639476513 1.0 0.2489383016237663 4 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8790807409962054 1.9363449744584624 0.0528254639476513 1.0 0.2489383016237663 4 P67812 1
Golgi to er retrograde transport 0.4031771057536071 1.9362480192720335 0.052837331826127 1.0 0.2489383016237663 73 Q9Y3B3,Q9P2W9,Q12981,Q86Y91,Q13561,O15260,O43731,Q10472,Q9BUF5,P04350,O75935,Q15363,P49755,Q9BVA1,Q13885,P24390,Q6NUQ1 17
Cytochrome p450 arranged by substrate type 0.877532158157724 1.931013037490216 0.0534814401443415 1.0 0.2496545621580589 3 Q16850 1
Cytoprotection by hmox1 0.4227292104758247 1.9172220921668208 0.0552097225742507 1.0 0.2517546479800637 62 P30519,P28072,P13073,Q8TCT9,P61289,P33527,P00403,P09601,O75880,Q9UNM6,P20618,P49721,O43819 13
Transport of connexons to the plasma membrane 0.8733650416171203 1.913199281314658 0.0557225455008751 1.0 0.2517546479800637 4 Q9BVA1,Q13885,P04350 3
Gap junction assembly 0.8733650416171203 1.913199281314658 0.0557225455008751 1.0 0.2517546479800637 4 Q9BVA1,Q13885,P04350 3
Cardiac conduction 0.6597258899534539 1.9129535168028164 0.05575400345323 1.0 0.2517546479800637 11 P23634,P20020,P05023 3
Ion homeostasis 0.6597258899534539 1.9129535168028164 0.05575400345323 1.0 0.2517546479800637 11 P23634,P20020,P05023 3
Activation of ampk downstream of nmdars 0.7859579847591419 1.912858536734598 0.0557661649015668 1.0 0.2517546479800637 6 Q9BVA1,Q13885,Q9BUF5,P04350 4
Slc transporter disorders 0.4644389540804579 1.9022671339152817 0.0571362400799566 1.0 0.2562916328187193 35 P11166,Q8NFH5,Q99567,P35613,P53985,Q8N1F7,O00400,Q9BTX1,P08195,O15504 10
Pre notch processing in golgi 0.830428676810584 1.894706209829313 0.0581313345966179 1.0 0.259924820935196 5 Q9UBV2,Q15363 2
Post translational modification synthesis of gpi anchored proteins 0.6885444658491389 1.880202509989406 0.0600804836700481 1.0 0.2645227695257328 9 Q5H8A4,O43292 2
Intrinsic pathway of fibrin clot formation 0.7560903149138509 1.8485061747170144 0.0645291519533142 1.0 0.277910826203844 2 P42785 1
Formation of fibrin clot clotting cascade 0.7560903149138509 1.8485061747170144 0.0645291519533142 1.0 0.277910826203844 2 P42785 1
Signaling by notch1 0.6649607517357213 1.8448915029248607 0.0650533229700087 1.0 0.2782218297248611 10 Q96J02,P49768,Q92542 3
Rac2 gtpase cycle 0.4432871819655219 1.8427068595397027 0.0653718219581129 1.0 0.2782218297248611 40 Q14739,Q86XL3,P49257,Q13505,Q9H0H5,P42166,P50402,Q9Y512,O15173,O00459,Q9Y2U8,P42167 12
Unfolded protein response upr 0.4329625040325306 1.8369816758277908 0.0662126005497405 1.0 0.2800075035296256 43 P61421,O43731,Q9Y5M8,P43307,O76024,O95070,O14773 7
Initiation of nuclear envelope ne reformation 0.5725771181183626 1.8279310335729455 0.0675599028157267 1.0 0.2839943220158095 16 Q14739,Q86XL3,P42166,P50402,P02545,P42167 6
Diseases of glycosylation 0.4995983079639723 1.826311130904205 0.0678034095318707 1.0 0.2841671253216312 24 Q9BV10,P16278,Q9BT22,Q8NCH0,O43505,Q96AA3,P10619,P06865,Q9H3H5 9
Amino acid transport across the plasma membrane 0.764719896909014 1.81774463151268 0.0691031727621738 1.0 0.2856233467279587 6 Q9H2J7,P30825,P08195,Q96QD8 4
Metabolism of steroid hormones 0.764625619417068 1.8173205383417832 0.069168046928423 1.0 0.2856233467279587 6 Q53GQ0,O95772 2
Reduction of cytosolic ca levels 0.8454617136428838 1.7995471130077116 0.071932178378556 1.0 0.293583658265967 4 P23634,P20020 2
Platelet calcium homeostasis 0.8454617136428838 1.7995471130077116 0.071932178378556 1.0 0.293583658265967 4 P23634,P20020 2
Trafficking and processing of endosomal tlr 0.7448009506833079 1.7957321793731438 0.0725371214757735 1.0 0.2946847920620983 2 Q99538 1
Disorders of transmembrane transporters 0.3785994543231654 1.7874031402124375 0.0738723544610699 1.0 0.2946847920620983 80 Q8NFH5,Q99567,P53985,Q8N1F7,O00400,P28072,P62191,P61289,Q9UNM6,P49721,O15504,Q9UBV2,P11166,Q9BUN8,Q9NP58,P35613,Q9BTX1,P20618,P08195,Q9GZP9 20
Cellular response to chemical stress 0.3930026416854632 1.7868647528654025 0.0739593505427449 1.0 0.2946847920620983 72 P30519,P28072,P13073,Q8TCT9,P62191,P61289,P33527,P00403,P09601,O75880,Q9UNM6,P20618,P49721,O43819,Q8TED1 15
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7427213309566292 1.7859899478200632 0.0741008857406235 1.0 0.2946847920620983 2 O00767 1
Notch2 activation and transmission of signal to the nucleus 0.8417921728763554 1.784756226584219 0.0743008663746316 1.0 0.2946847920620983 3 P49768 1
Notch3 activation and transmission of signal to the nucleus 0.8417921728763554 1.784756226584219 0.0743008663746316 1.0 0.2946847920620983 3 P49768 1
Noncanonical activation of notch3 0.8417921728763553 1.784756226584219 0.0743008663746316 1.0 0.2946847920620983 3 P49768 1
Signaling by notch2 0.8417921728763554 1.784756226584219 0.0743008663746316 1.0 0.2946847920620983 3 P49768 1
Keratan sulfate keratin metabolism 0.8013723712310152 1.7712568606195969 0.0765179976505929 1.0 0.3000858853609613 5 P06865,O43505,P16278 3
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5043727745472207 1.7569853923414145 0.0789202991018684 1.0 0.3027434424563479 21 Q9BV10,P16278,Q9BT22,Q96AA3,Q86YN1,P10619,Q9H3H5 7
Synthesis of pa 0.6796968509238619 1.7525267710893015 0.0796832706776098 1.0 0.3048373624832812 8 Q86UL3,P43304,O15228,Q9NPH0 4
Cargo concentration in the er 0.5821287000366523 1.7486958464469364 0.0803436084013002 1.0 0.3065283320527869 14 Q96PC5,Q12907,Q15363,Q13190,P49755,P53634 6
Sialic acid metabolism 0.8266040343460999 1.7221527205537932 0.085041856900168 1.0 0.3155937318835835 4 P10619 1
Vitamin d calciferol metabolism 0.8246330504662072 1.7139723842035754 0.0865337978015892 1.0 0.3180456861608148 3 P38435 1
Adp signalling through p2y purinoceptor 1 0.7260843731432014 1.7078343590322524 0.0876670817377278 1.0 0.3197002149604414 2 P29992 1
G protein activation 0.7260843731432014 1.7078343590322524 0.0876670817377278 1.0 0.3197002149604414 2 P29992 1
Phase i functionalization of compounds 0.5626009339815546 1.693404142927122 0.0903785668425014 1.0 0.3287344762872332 15 P07099,Q16850,P16435,O43169 4
Creb phosphorylation 0.7225193107546098 1.6910390584322648 0.0908293431103699 1.0 0.3295204075632025 2 Q15418 1
Depolymerisation of the nuclear lamina 0.6351611735173563 1.6879915865121191 0.0914128440136583 1.0 0.330602268180216 10 P42167,P02545,P42166,P50402 4
Signaling by erbb4 0.6501281856987208 1.6836128128057626 0.0922565208948806 1.0 0.3312740545688298 9 Q96J02,P46934,P49768,Q92542 4
Muscle contraction 0.4776656165186974 1.680738794234933 0.0928136617492814 1.0 0.3320016544848687 25 P16615,P04083,P20020,P05023,P23634,P08670 6
Neuronal system 0.4109565492643624 1.6735669817692715 0.0942157321963312 1.0 0.3340375959688109 53 O75955,P07196,Q96RD7,P21964,O95197,P04350,Q9BUF5,P10586,P10644,Q14168,Q9BVA1,Q13885,P52292,Q96QD8 14
Rhog gtpase cycle 0.420895054099464 1.657712486291949 0.0973755123559096 1.0 0.3409357090965017 41 Q14739,Q86XL3,P49257,P42166,O95202,P50402,Q13190,P34897,P84095,O15173,Q9Y2U8,P42167 12
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.6595659640731062 1.6514392836967593 0.0986489089601554 1.0 0.3445349954727817 8 P11310 1
Pyruvate metabolism 0.5449363697603082 1.6499581903752023 0.0989514876785124 1.0 0.3447342151380435 16 O43708,P21796,P35613,P53985,Q15118 5
Glycerophospholipid catabolism 0.7130124777183654 1.6461761050856212 0.0997275073027863 1.0 0.3465777729037426 2 Q8IY17 1
Transferrin endocytosis and recycling 0.6084519391319729 1.633028806580813 0.1024629382762012 1.0 0.3508730861946013 11 Q15904,Q93050,Q9Y487 3
Peroxisomal protein import 0.494481289685987 1.6314495407864869 0.1027954987737733 1.0 0.3511554264680725 20 Q9BY49,O00116,O15228,O75381,O15254,Q15067,O75521 7
Insulin receptor recycling 0.6202125879270812 1.60835446994025 0.1077575673123201 1.0 0.3642675970156832 10 Q15904,Q93050,Q9Y487 3
Interleukin 4 and interleukin 13 signaling 0.5857864097653527 1.6020450988472026 0.1091456370330576 1.0 0.3642675970156832 12 P09601,P04083,P08670 3
Signaling by hedgehog 0.3944252475719278 1.6016709643621077 0.1092283891336201 1.0 0.3642675970156832 62 P28072,Q96J02,P62191,P61289,P48729,Q9BUF5,P04350,P10644,Q9UNM6,Q9BVA1,P49721,Q13885,P78536,P20618,Q9UBV2,Q9GZP9 16
Attachment of gpi anchor to upar 0.7599734540827787 1.5932315482558963 0.1111082563016312 1.0 0.3696587484537683 5 O43292 1
Acyl chain remodelling of pc 0.7919762258543843 1.5783886455377725 0.1144763521019553 1.0 0.3737521610654895 3 Q9NP80,Q7L5N7 2
Signaling by notch1 pest domain mutants in cancer 0.6433331640676608 1.569270495352753 0.1165849241380683 1.0 0.3754248474537796 8 P49768,Q92542 2
Nuclear signaling by erbb4 0.7524601557136775 1.560683699013122 0.1185983992813439 1.0 0.3789983194364305 5 P49768,Q92542 2
Anchoring of the basal body to the plasma membrane 0.4378913418842732 1.5585164708801549 0.1191108666238927 1.0 0.3789983194364305 32 O95684,Q13561,P07437,Q9H6D7,P04350,O94927,P41208 7
Kinesins 0.507068074928181 1.5469683906042393 0.1218708679848605 1.0 0.3830926824017277 18 Q9BVA1,Q86Y91,Q13885,P04350 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6086902005566036 1.546567622843262 0.1219675420467039 1.0 0.3830926824017277 10 Q9BU89,P38435,Q8NBJ7,O60725 4
Sealing of the nuclear envelope ne by escrt iii 0.5925582720730823 1.5446853490506804 0.1224223903775212 1.0 0.383663026986696 11 Q9BVA1,Q13885,P04350 3
Signaling by notch 0.3903202800714168 1.5405846007229498 0.1234179181650096 1.0 0.3846176170264238 61 P28072,P16615,Q96J02,P61289,Q92542,Q15363,Q9UNM6,P20618,P49768,P49721,P78536,Q9UBV2 12
Recruitment of mitotic centrosome proteins and complexes 0.4321178376912414 1.5402289440911554 0.1235045569769783 1.0 0.3846176170264238 33 O95684,Q13561,P07437,Q9H6D7,P04350,O94927,P41208 7
Regulation of pyruvate dehydrogenase pdh complex 0.6225211095289033 1.5400473115074895 0.1235488214237301 1.0 0.3846176170264238 9 P11177,O43708,Q15118,Q8NCN5,P09622 5
Assembly and cell surface presentation of nmda receptors 0.6069247601039818 1.5370708727400983 0.1242759548076573 1.0 0.3860253109512186 10 P07196,Q12959,Q9BUF5,P04350,Q9BVA1,Q14168,Q13885 7
Stimuli sensing channels 0.6214531720880828 1.534458044188421 0.1249170073658614 1.0 0.3864237732105263 9 Q9C0H2,P27105 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.5243875160133038 1.5156881092883414 0.1295982357340601 1.0 0.3976429460029281 16 P04439,Q6P179,Q03519,Q9NZ08,Q03518,P27824 6
Diseases associated with glycosaminoglycan metabolism 0.7761278284073356 1.5129912680124504 0.1302818768955462 1.0 0.3976429460029281 4 Q8NCH0 1
Chondroitin sulfate dermatan sulfate metabolism 0.7761278284073356 1.5129912680124504 0.1302818768955462 1.0 0.3976429460029281 4 Q8NCH0 1
Wax and plasmalogen biosynthesis 0.7755626831156253 1.5106354440845833 0.1308813582914827 1.0 0.3981477682296736 4 O00116,O15228 2
Keratan sulfate degradation 0.7752142405930369 1.5091828213989258 0.1312520689698286 1.0 0.3981477682296736 4 P06865,P16278 2
Cdc6 association with the orc origin complex 0.774863636957463 1.5077210894435955 0.1316259256038421 1.0 0.3981477682296736 4 Q9UJA3 1
Rhoa gtpase cycle 0.3959539800283624 1.5067873243832175 0.1318651796487167 1.0 0.3981477682296736 52 Q14739,Q9NRG9,P42166,O15173,Q8NBN3,P30519,Q86VI3,Q13190,Q15904,P51572,Q07021,Q5T8D3,P27105,O75955,P49257,Q9H0H5,Q96HY6,O00459,Q96CS3,P42167 20
Role of lat2 ntal lab on calcium mobilization 0.77453565152676 1.5055905572890296 0.1321723139982 1.0 0.3982187314452208 3 O00459 1
G alpha i signalling events 0.4582912576906373 1.502196151576256 0.1330464584329962 1.0 0.3999940634687938 24 P04083,P22466,Q9NZJ7,P07602,P52292 5
Regulated proteolysis of p75ntr 0.7706802462272269 1.4902721866657478 0.1361526825376899 1.0 0.4023903309869785 4 P49768,Q92542 2
Interactions of vpr with host cellular proteins 0.4188756161865674 1.489509699235358 0.1363532011735924 1.0 0.4023903309869785 35 Q7Z3B4,Q8NFH5,Q99567,P52294,Q8N1F7,Q9BTX1,P12236,O15504,P12235 9
Ns1 mediated effects on host pathways 0.4186266441842429 1.487211729247054 0.1369588991695192 1.0 0.4023903309869785 35 Q7Z3B4,Q8NFH5,Q99567,P52294,Q8N1F7,Q9BTX1,P52292,O15504 8
Alpha oxidation of phytanate 0.7682894245582041 1.480293998904245 0.1387948040686408 1.0 0.4033600223884092 4 P51648,Q9BY49 2
Abc family proteins mediated transport 0.3900162070325652 1.4772106851172442 0.1396191704555545 1.0 0.4033600223884092 56 Q9BUN8,P28072,P62191,P40855,P61289,P33527,Q9NP58,Q9UNM6,P20618,P49721,Q9UBV2,Q9GZP9 12
Biological oxidations 0.3927872357238633 1.4407190290261118 0.1496640767224453 1.0 0.4220147846054357 45 P07099,P16435,O43708,P21964,O43169,Q8TB61,Q9UJ14,Q9NUJ1,Q16850 9
Aurka activation by tpx2 0.4205893907669734 1.436720813640478 0.1507973384528984 1.0 0.4234389263757388 33 O95684,Q13561,P07437,Q9H6D7,P04350,O94927,P41208 7
Synthesis of pg 0.7545319465081731 1.421847471882342 0.1550705349694991 1.0 0.4319822045578906 3 Q8WUK0,Q8IV08 2
Rho gtpases activate iqgaps 0.5689946576753939 1.412477765828773 0.1578093329104213 1.0 0.4361502035555739 11 Q9BVA1,Q13885,Q9BUF5,P04350 4
Beta oxidation of decanoyl coa to octanoyl coa coa 0.6751314032660735 1.4081846944461605 0.1590763871809433 1.0 0.4382069441121871 6 P11310 1
Ptk6 regulates proteins involved in rna processing 0.7497771173848449 1.4019130739853798 0.160941205865551 1.0 0.4421200180455104 3 Q07666,O75525 2
O linked glycosylation 0.7138383588080552 1.3924455025671223 0.1637875335901593 1.0 0.446724355658225 5 Q10472 1
Other semaphorin interactions 0.6571598336304291 1.3809802480791882 0.1672850339004925 1.0 0.4534134895681304 2 P05556 1
E2f enabled inhibition of pre replication complex formation 0.6681677029225752 1.3758977570738018 0.1688532897391506 1.0 0.4567373265364173 6 Q9UJA3 1
Metabolism of steroids 0.3866205854315295 1.374901536752439 0.1691619727912656 1.0 0.4567373265364173 43 Q15392,O75845,O95772,Q14534,P37268,Q53GQ0,P04035,Q15800,Q14849,Q16850,P38435,P04062 12
Copi mediated anterograde transport 0.3802297239526303 1.369797968965882 0.1707499762566751 1.0 0.4601400511792166 56 Q9Y3B3,Q13561,O43731,Q9BUF5,P04350,Q13190,O75935,Q15363,P49755,Q9BVA1,Q13885,O95249,P24390 13
Pregnenolone biosynthesis 0.7366373684448952 1.3478543770126288 0.1777052243977146 1.0 0.4743310552364854 4 O95772 1
Response to elevated platelet cytosolic ca2 0.3964470554770536 1.3437980669302387 0.1790136947792626 1.0 0.4760234107654452 38 Q9BWS9,Q12846,O43852,Q92520,Q96JJ7,Q6UXV4,Q06481,Q9NZJ7,O94919,P07602,Q9NTK5,Q8NBX0,Q9NUQ9,P13473 14
Assembly of the orc complex at the origin of replication 0.597264619394323 1.3333180858394933 0.1824274409877826 1.0 0.4832606172582016 8 O60684,P52294 2
Endosomal vacuolar pathway 0.7324613555291247 1.3303460247106502 0.1834042895081027 1.0 0.4849333756485428 4 P04439,Q9UIQ6,P10321 3
Carboxyterminal post translational modifications of tubulin 0.6978469418134805 1.3224375891875786 0.1860224788575177 1.0 0.4876346299390033 5 Q9BVA1,Q13885,P04350 3
Release of apoptotic factors from the mitochondria 0.7307356794221203 1.3220169453457462 0.1861625082958018 1.0 0.4876346299390033 3 Q9NR28 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5762922334314627 1.2959988102924762 0.1949758947705273 1.0 0.5031387987991713 9 Q9UJX2,Q96DE5,Q12834,Q9UJX3 4
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.6884441062580554 1.2812140434171542 0.2001184947641914 1.0 0.508841163337868 5 P05141,P12235,P12236 3
Cilium assembly 0.3650621083208162 1.2787310536730383 0.2009917803238212 1.0 0.508841163337868 63 O95684,Q13561,P07437,Q9H6D7,P04350,Q10713,Q9BUF5,O75935,Q9BVA1,O94927,Q13885,A6NIH7,O43924,P41208 14
Synthesis of very long chain fatty acyl coas 0.5971100352869305 1.262513361063988 0.2067641216093543 1.0 0.5194358829391517 7 Q9NZ01,Q53GQ0 2
Abc transporters in lipid homeostasis 0.7162825380169109 1.2613510295172865 0.2071824034515135 1.0 0.5194358829391517 3 P40855 1
Integrin cell surface interactions 0.6426304904869576 1.257157956158419 0.2086964442485368 1.0 0.5213697646351347 6 P35613 1
Platelet adhesion to exposed collagen 0.6295306001188439 1.2494237429667572 0.2115101287962497 1.0 0.5255933112034242 2 P05556 1
Fcgr activation 0.6292335115864611 1.2480105358382114 0.2120271988710425 1.0 0.5259473272348828 2 P07948 1
Beta oxidation of octanoyl coa to hexanoyl coa 0.6769920292312002 1.2309717977492496 0.2183334123988687 1.0 0.5368478301366229 5 P11310 1
Gap junction trafficking and regulation 0.549618636586524 1.2250559848993503 0.2205541274503479 1.0 0.5388054827835714 10 Q9BVA1,Q13885,P04350 3
Metabolism of fat soluble vitamins 0.5868510972119285 1.2108945878014654 0.2259358071460329 1.0 0.5478650660328673 7 Q9Y5Z9 1
Transmission across chemical synapses 0.3720799310077713 1.1998732293698993 0.2301885783654371 1.0 0.5546197301235634 42 P52292,Q9UBI6,Q15418,O14936,P21964,Q12959,Q9BUF5,P04350,P10644,Q14168,P63096,Q9BVA1,O75915,P07196,P54619,Q13885,P53680,O94925,Q96QD8 19
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6185383244206861 1.1971768362025363 0.2312376364177213 1.0 0.5546197301235634 2 P51659 1
Abc transporter disorders 0.3691385980798375 1.1967501386736774 0.2314039580162057 1.0 0.5546197301235634 45 Q9BUN8,P28072,P61289,Q9NP58,Q9UNM6,P20618,P49721,Q9UBV2,Q9GZP9 9
Hedgehog off state 0.3654123591844156 1.1843034600307552 0.2362929596754912 1.0 0.560917469548161 53 P28072,P62191,P61289,P48729,Q9BUF5,P04350,Q9BVA1,Q9UNM6,Q13885,P49721,P20618,Q96J02 12
Transport to the golgi and subsequent modification 0.3320686235965474 1.1823727811756113 0.2370578183779963 1.0 0.5612633676268244 81 Q9Y3B3,Q13561,O60476,O43731,Q96PC5,P04350,Q15363,Q9BUF5,Q12907,Q9BVA1,Q13190,Q13885,P53634,O75935,P49755,O95249,P24390 17
Antigen activates b cell receptor bcr leading to generation of second messengers 0.6961654940175881 1.1769913514776924 0.2391989581973654 1.0 0.5651065551469494 3 P62993 1
Signaling by insulin receptor 0.4731768807458602 1.1749670594570307 0.2400078947328463 1.0 0.565387725176034 16 Q15904,Q93050,P61421,Q9Y487 4
Ros and rns production in phagocytes 0.5499540504074015 1.155455438196586 0.2479039708682726 1.0 0.5771446419090517 9 Q93050,Q9Y487 2
Hemostasis 0.3064021483509941 1.1491629766258529 0.2504887841509906 1.0 0.5780650296015137 134 P16615,Q6UXV4,P53985,P23634,O94919,Q08722,P07602,Q9NTK5,Q86Y91,Q8N2K0,P20020,Q9BUF5,P04350,P10644,Q8NBX0,P13473,Q12846,Q96JJ7,Q9UPY5,Q06481,P42785,Q9BVA1,P62993,Q9NUQ9,O00459,P46108,Q9BWS9,Q8IWA4,O43852,P35613,Q9NZJ7,P84095,P08195,Q13885,Q92520 35
Pre notch expression and processing 0.5074040801204942 1.141611255707736 0.2536156433158201 1.0 0.5804084376935793 12 Q9UBV2,Q15363 2
Synthesis of pc 0.6563929934315935 1.1405942514326013 0.2540388105751354 1.0 0.5804084376935793 5 Q8WWI5,Q8NF37 2
Er to golgi anterograde transport 0.3320065617926809 1.1381316081978765 0.2550655313795857 1.0 0.5804084376935793 77 Q9Y3B3,Q13561,O43731,Q96PC5,P04350,Q15363,Q9BUF5,Q12907,Q9BVA1,Q13190,Q13885,P53634,O75935,P49755,O95249,P24390 16
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.569890858976746 1.1254529551278971 0.2603971419496804 1.0 0.5842944972751254 7 Q92692,P04439,P01889,Q5KU26,P10321 5
Potential therapeutics for sars 0.3776310075732597 1.1218008978303005 0.2619471044081334 1.0 0.5847670474580187 36 P21964,Q99720,P05023,P07437 4
Apc cdc20 mediated degradation of nek2a 0.5158405710254994 1.109991961172852 0.2670024905627897 1.0 0.5912799633283229 11 Q9UJX2,Q96DE5,Q12834,Q9UJX3 4
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5158405710254994 1.109991961172852 0.2670024905627897 1.0 0.5912799633283229 11 Q9UJX2,Q96DE5,Q12834,Q9UJX3 4
Inflammasomes 0.6105032839974172 1.1074180387769486 0.2681132303648312 1.0 0.5918726028808539 6 P09601 1
The nlrp3 inflammasome 0.6105032839974172 1.1074180387769486 0.2681132303648312 1.0 0.5918726028808539 6 P09601 1
Diseases of carbohydrate metabolism 0.5527000762414833 1.1024219065232677 0.2702782920821542 1.0 0.5938508952790995 8 P54802,P15586,P16278 3
Apc c cdc20 mediated degradation of cyclin b 0.5141325884630157 1.1002062312509997 0.2712422762307236 1.0 0.5944478127417789 11 Q9UJX2,Q96DE5,Q12834,Q9UJX3 4
Metabolism of folate and pterines 0.5635319072787214 1.093409284821915 0.2742141387461232 1.0 0.5967353277771599 7 Q9H2D1 1
G alpha z signalling events 0.6452306007832833 1.0916732233587552 0.2749767586715541 1.0 0.5967353277771599 5 P08754,Q9UBI6,P63096 3
Intra golgi traffic 0.4419522173004803 1.0863892981328642 0.2773067942933775 1.0 0.5989826756736956 18 O95249,O00461,O60476,Q8TBA6 4
Sulfur amino acid metabolism 0.5473420722459845 1.0745909115713983 0.2825579226327956 1.0 0.60507154071736 8 Q9UBX3 1
Regulation of hmox1 expression and activity 0.3570370206479133 1.0705321738268323 0.2843798348969071 1.0 0.60507154071736 45 P28072,Q8TCT9,P61289,P09601,Q9UNM6,P20618,P49721 7
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.6701126761039053 1.0690716879781403 0.2850373679324338 1.0 0.60507154071736 4 P11310 1
Constitutive signaling by aberrant pi3k in cancer 0.6007327326339449 1.0619106433022134 0.2882762528170368 1.0 0.60507154071736 6 O00459,P84095 2
Nuclear envelope breakdown 0.3582782057910848 1.059154133688919 0.289529589648589 1.0 0.60507154071736 42 Q7Z3B4,Q8NFH5,Q99567,P42166,P50402,Q8N1F7,Q9BTX1,O15504,P02545,Q9Y2U8,P42167 11
Hedgehog ligand biogenesis 0.3558005718491159 1.058509902928265 0.2898230384005096 1.0 0.60507154071736 43 P28072,P62191,P61289,Q9UNM6,P20618,P49721,P78536,Q9UBV2,Q9GZP9 9
N glycan trimming in the er and calnexin calreticulin cycle 0.437685152218726 1.0558320417457645 0.2910449565280766 1.0 0.606271689859673 18 Q9BUN8,P62191,Q9NYU1,Q9UBV2,Q9GZP9 5
Post chaperonin tubulin folding pathway 0.5297011473059101 1.0470132333947924 0.29509347482302 1.0 0.6119811501499559 9 Q9BVA1,Q13885,P04350 3
P75 ntr receptor mediated signalling 0.4448661594117158 1.0423169182251184 0.2972647711301279 1.0 0.6146682454590569 17 Q9NQC3,P49768,Q92542 3
Vitamin c ascorbate metabolism 0.6632215640521525 1.0394715364736136 0.2985854891209052 1.0 0.614783367941532 3 P11166 1
Rac3 gtpase cycle 0.3651114130384972 1.03936699857331 0.298634086136841 1.0 0.614783367941532 38 Q14739,Q6IAA8,Q9UQB8,P49257,Q9H0H5,P42166,P50402,P29317,O15173,O00459,Q15758,Q9Y2U8,P42167 13
Gaba receptor activation 0.6620095124851305 1.035278755456298 0.300538748292511 1.0 0.6148912065005981 4 P08754,Q9UBI6,P63096 3
Adp signalling through p2y purinoceptor 12 0.6620095124851305 1.035278755456298 0.300538748292511 1.0 0.6148912065005981 4 P08754,Q9UBI6,P63096 3
Gaba b receptor activation 0.6620095124851305 1.035278755456298 0.300538748292511 1.0 0.6148912065005981 4 P08754,Q9UBI6,P63096 3
Intraflagellar transport 0.4894525140309994 1.0346299164523536 0.3008417771462679 1.0 0.6148912065005981 12 Q92973,Q9BUF5,P04350,Q9BVA1,Q13885 5
Adenylate cyclase inhibitory pathway 0.66181277860327 1.0336192223202474 0.3013142094532846 1.0 0.6148912065005981 3 P08754,P63096 2
Adrenaline noradrenaline inhibits insulin secretion 0.6618127786032701 1.0336192223202474 0.3013142094532846 1.0 0.6148912065005981 3 Q9UBI6,P63096 2
Role of phospholipids in phagocytosis 0.6608950156578819 1.030636838449969 0.3027111541232832 1.0 0.6159513918682459 4 Q8IV08 1
Tysnd1 cleaves peroxisomal proteins 0.6308369833368229 1.0287185184248064 0.303611965323515 1.0 0.6168903029149277 5 Q15067 1
Signaling by notch3 0.5925346722874326 1.0237745875012627 0.3059417560720883 1.0 0.618574273238683 6 P49768 1
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.6576523031203577 1.0163538086492985 0.309460933491013 1.0 0.6206902151734032 3 P62942,Q9Y624 2
Translation of sars cov 1 structural proteins 0.5473228423722531 1.011790896889088 0.3116380433996633 1.0 0.6240721371612792 7 Q10472,P27824 2
Defective cftr causes cystic fibrosis 0.3513069701829165 1.010958968595644 0.3120360685806396 1.0 0.6240721371612792 44 Q9BUN8,P28072,P61289,Q9UNM6,P20618,P49721,Q9UBV2,Q9GZP9 8
Scavenging by class a receptors 0.65503845800515 1.0062704837395955 0.3142854748523045 1.0 0.6267852367793117 4 Q5KU26,P02792 2
Synaptic adhesion like molecules 0.5878125948369389 1.0018355425684335 0.3164230279838798 1.0 0.6283704827289494 6 P10586,O75955,Q12959,O95197 4
G alpha s signalling events 0.6217392831134169 0.989036951902964 0.3226450627409769 1.0 0.6344449132889799 5 P08754,Q9UBI6,P63096 3
Neurotransmitter receptors and postsynaptic signal transmission 0.3669152708893695 0.972934132514264 0.3305860395959357 1.0 0.643748681820657 34 P07196,P54619,Q12959,Q9BUF5,P04350,P53680,P10644,Q14168,Q9BVA1,Q13885,P52292,P63096,Q9UBI6,Q15418,O14936 15
Signaling by notch4 0.3468628240688754 0.9658828515626354 0.3341028041491627 1.0 0.6470073614143785 43 P28072,P61289,Q92542,Q9UNM6,P20618,P49768,P49721 7
Nr1h2 and nr1h3 mediated signaling 0.6153835402153243 0.9613810158317004 0.336360626052602 1.0 0.6504825330273459 5 Q8NB78,Q9HCE1,O00767 3
Free fatty acids regulate insulin secretion 0.6395245170876682 0.9414879351261564 0.3464548691601399 1.0 0.6645117982251864 3 O60488,P29992 2
Striated muscle contraction 0.6100006926726637 0.9380084456672306 0.3482400698380998 1.0 0.6670246358154055 5 P08670 1
Regulation of signaling by cbl 0.5322036885898758 0.935859527061339 0.3493455178772122 1.0 0.6682303911438774 7 P62993,O00459 2
Translocation of slc2a4 glut4 to the plasma membrane 0.3567937991797869 0.9221549434399154 0.3564477612479593 1.0 0.6777021588211609 36 Q12846,P11233,Q9BUF5,P04350,Q9BVA1,Q9UIQ6,Q13885,P61026 8
Aquaporin mediated transport 0.5703017294249626 0.9207261008997736 0.3571934455325207 1.0 0.6777021588211609 6 Q99797 1
Diseases associated with n glycosylation of proteins 0.4927796567915863 0.9113039012141492 0.3621352714638308 1.0 0.6824670082351927 10 Q9BV10,Q96AA3,Q9BT22,Q9H3H5 4
Platelet homeostasis 0.491383332707218 0.903596641082961 0.3662093230170515 1.0 0.683720597760559 10 P23634,P20020 2
Regulation of plk1 activity at g2 m transition 0.3514975031063905 0.8880576303729046 0.3745097521302156 1.0 0.6929662639470957 37 O95684,Q13561,P07437,Q9H6D7,P04350,O94927,P41208 7
Ca dependent events 0.5224426007970973 0.8870153234974967 0.3750706505526255 1.0 0.6929662639470957 7 P52292 1
Degradation of the extracellular matrix 0.4628649849587326 0.8761052358003281 0.3809728266726928 1.0 0.7001123673409172 12 P49768,P35613,Q92542 3
Signal amplification 0.5175362451395413 0.8625351648455237 0.3883930909267383 1.0 0.7100311193504435 7 Q9UBI6,P29992,P63096,P08754,Q14344 5
Signaling by retinoic acid 0.4470139292659636 0.8584315737841259 0.3906541992685308 1.0 0.71194525472123 13 P11177,Q15120,P50416,Q8NBN7,Q15118,P09622 6
Molecules associated with elastic fibres 0.6190193164933147 0.8577094824401642 0.3910529026645539 1.0 0.71194525472123 3 P06756,P05556 2
Elastic fibre formation 0.6190193164933147 0.8577094824401642 0.3910529026645539 1.0 0.71194525472123 3 P06756,P05556 2
Tie2 signaling 0.6188339180424209 0.8569573183801455 0.3914684733937248 1.0 0.71194525472123 3 O00459 1
Extracellular matrix organization 0.3444846839390754 0.8554743222239171 0.3922886138450341 1.0 0.7125138600755859 39 P13674,P35613,Q92542,Q08722,P49768,P78536,O75718 7
Inla mediated entry of listeria monocytogenes into host cells 0.5407011289364347 0.8336558538394155 0.4044749416437312 1.0 0.7268189065253274 2 O60716 1
Aggrephagy 0.4292839703317597 0.8302142408322813 0.4064176650238 1.0 0.7268189065253274 15 Q9BVA1,P08670,Q13885,P04350 4
Wnt mediated activation of dvl 0.5377302436126048 0.8201814251548792 0.4121126893340789 1.0 0.7314869985145978 2 P19784 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.3325236093444528 0.8129591486697602 0.4162414802689889 1.0 0.7363748733571678 49 P28072,P62191,P61289,P04350,Q9BVA1,Q9UNM6,Q13885,P49721,P20618 9
Gpvi mediated activation cascade 0.5466883128743671 0.8122781083156427 0.4166320692019647 1.0 0.7363748733571678 6 O00459 1
Phosphorylation of the apc c 0.4616722779562443 0.7997324044701872 0.4238658540904536 1.0 0.7438845739287461 11 Q9UJX2,Q96DE5,Q9UJX3 3
Signal regulatory protein family interactions 0.6039702419128958 0.797020575323815 0.4254390818322435 1.0 0.744783629541733 3 Q08722 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3551777216554889 0.7900647174272133 0.4294899738267688 1.0 0.7490731965873085 31 Q13561,Q9BUF5,P04350,O75935,Q9BVA1,Q13885,Q15185 7
Copi independent golgi to er retrograde traffic 0.3598961707004613 0.7885118337782454 0.4303973794085736 1.0 0.7497244673568702 29 Q13561,Q10472,Q9BUF5,O75935,P04350,Q9BVA1,Q13885 7
Death receptor signalling 0.3616660972918777 0.7833221942392556 0.4334379332503808 1.0 0.7519869988598631 28 O95429,Q8TCT8,Q9NQC3,Q92542,P49768 5
Miscellaneous transport and binding events 0.5386038238904116 0.7754939750156945 0.4380478242762986 1.0 0.7564811135103606 6 Q8IWT6,Q9H0U3 2
Tp53 regulates metabolic genes 0.3493256038371743 0.7594775901106423 0.447566914660142 1.0 0.7674498762822118 32 Q6IAA8,P13073,Q15382,P54619,Q9Y2Q5,P00403,O75880,P20674,O94925,O43819 10
Mitotic g2 g2 m phases 0.2913391439804788 0.7586189127878659 0.4480805557325729 1.0 0.7674498762822118 93 Q13561,O95684,P28072,P07437,P62191,P61289,Q9H6D7,P04350,Q9BUF5,O94927,Q9BVA1,Q9UNM6,Q13885,P49721,P20618,P41208 16
Transcriptional regulation by ventx 0.4277307108866316 0.7392694443595552 0.4597433996392754 1.0 0.7758169868912774 13 Q13042,Q9UJX2,Q96DE5,Q9UJX3 4
Post translational protein modification 0.2632601794641999 0.7354828874024432 0.4620454581363133 1.0 0.775952079108489 417 Q9Y3B3,O43681,Q8NFH5,Q9NYU1,P21796,Q9BT22,Q8N1F7,O43505,Q96AA3,O75340,P20337,P45880,P24390,Q9H490,P46977,Q9BV10,Q02818,P28072,O60476,P16278,Q9H0U3,O43731,P62191,P61289,Q9BUF5,P04350,Q12907,Q13190,Q9UNM6,P49721,Q9UBV2,Q9BTE7,Q8NBJ7,O43292,Q9H3H5,Q15388,Q13561,O43493,P04439,Q9BU89,Q06481,O75935,Q15363,O60870,P07237,Q9BVA1,P49755,O60725,P53634,Q9UJW0,Q86YN1,P10619,Q5H8A4,P61026,P38435,Q8NB78,Q9BUN8,O43852,O75381,O95249,Q10472,Q96PC5,O76024,Q9BTX1,Q969Q5,Q13885,P20618,P41208,Q07065,Q9GZP9,Q9Y277 71
G protein mediated events 0.4389551963611726 0.7343606748003604 0.4627289475475762 1.0 0.775952079108489 12 P10644,O43865,P52292,P63096 4
Rhoj gtpase cycle 0.3668273196113695 0.7336870567046119 0.4631394888126166 1.0 0.775952079108489 22 P42167,P42166,P27105,O00459 4
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4255152503130139 0.7256491481335083 0.4680538832558381 1.0 0.7796417240282527 13 Q96J02,P09601 2
Heme biosynthesis 0.5269529307634699 0.722882916325241 0.4697518200934589 1.0 0.7804650051914007 6 Q7KZN9,P22830 2
Constitutive signaling by overexpressed erbb2 0.5834815039041605 0.7146056544396929 0.4748527497924644 1.0 0.7838880158745056 4 Q16543 1
Regulation of beta cell development 0.5127748068924667 0.7089101706932247 0.4783802231538752 1.0 0.787392536117281 2 Q13573 1
Collagen biosynthesis and modifying enzymes 0.4453709424617055 0.7072087492999073 0.4794367621871149 1.0 0.7877262119051609 11 P13674,Q32P28,P07237,O75718,O60568 5
Fgfr1 mutant receptor activation 0.4547370418943077 0.7025473600564838 0.4823378772875015 1.0 0.7902011431874588 10 Q92614,O95684,O95429 3
Cd28 co stimulation 0.464169696726127 0.6983482689868532 0.4849594195452158 1.0 0.7926461292683155 9 O00459 1
Energy dependent regulation of mtor by lkb1 ampk 0.47272741379144 0.690551800575199 0.489847246279588 1.0 0.7975215140331775 8 Q15382,Q6IAA8,P54619,Q9Y2Q5 4
Dap12 interactions 0.5179476543578031 0.6825963165709094 0.4948619622666443 1.0 0.8004449251409778 6 P62993,P10321,O00459 3
Neutrophil degranulation 0.2769993811105868 0.6728549734543281 0.5010395600622961 1.0 0.8053291792990446 178 P15586,Q92542,Q08722,P07602,P49768,Q9H7Z7,P30519,Q9H0U3,P16278,O15260,Q13510,Q9UNM6,Q93050,P27105,P13473,P04439,O00560,P07437,P42785,Q9NQX7,P61916,P53634,O00264,P02792,P10619,P61026,Q92820,P17900,O00584,Q9NZJ7,P84095,O75787,Q969Q5,P20618,O15121,Q07065,O43681 37
Binding and uptake of ligands by scavenger receptors 0.4570371213384023 0.6610816450595693 0.5085599556844325 1.0 0.808627607905938 9 Q8WTV0 1
Protein protein interactions at synapses 0.4019748564537085 0.6528250316471914 0.5138690841625069 1.0 0.8115547740879185 15 O75955,Q12959,O95197,P10586,Q14168,O14936 6
Calnexin calreticulin cycle 0.4342412214513192 0.6445888196766604 0.51919368207062 1.0 0.815377997345806 11 Q9UBV2,Q9NYU1,Q9GZP9 3
Dag and ip3 signaling 0.4633167123890945 0.6432827089032044 0.5200406739411101 1.0 0.8157956494003559 8 P52292 1
Synthesis of substrates in n glycan biosythesis 0.4112468743688312 0.638432465179096 0.5231922031631999 1.0 0.817997609399925 13 P10619,P16278 2
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.4955436720142736 0.6344937984494967 0.5257586127553548 1.0 0.8203235475710718 2 P24941 1
Cell death signalling via nrage nrif and nade 0.4415844719251315 0.6313880054950813 0.5277868567194766 1.0 0.8215218922773228 10 P49768 1
Maturation of sars cov 1 nucleoprotein 0.4931669637552067 0.6244126767117691 0.5323566019913031 1.0 0.825888032260541 2 P49840 1
Signaling by flt3 fusion proteins 0.5355674994245515 0.6231128958656389 0.5332103358863365 1.0 0.8262994609099519 5 Q92614,P62993 2
Cdt1 association with the cdc6 orc origin complex 0.3152526355866658 0.6000705990460559 0.548459185818519 1.0 0.8351807992290681 41 P28072,Q9Y619,P61289,Q9UJA3,Q9UNM6,P20618,P49721 7
Runx3 regulates p14 arf 0.4857397504456442 0.593224448267562 0.5530309529915534 1.0 0.8385587193377921 2 P25440 1
Dap12 signaling 0.5465798626543537 0.5718027353006334 0.5674556239975348 1.0 0.8539203602278016 4 O00459 1
Er quality control compartment erqc 0.4919272103662376 0.5685218427182527 0.569680678344439 1.0 0.8547515715131435 6 Q9UBV2,Q9GZP9 2
Signaling by egfr in cancer 0.5208681485898289 0.5638174598010379 0.5728783680868006 1.0 0.8547515715131435 5 Q16543 1
Constitutive signaling by egfrviii 0.5208681485898289 0.5638174598010379 0.5728783680868006 1.0 0.8547515715131435 5 Q16543 1
Constitutive signaling by ligand responsive egfr cancer variants 0.5208681485898289 0.5638174598010379 0.5728783680868006 1.0 0.8547515715131435 5 Q16543 1
Rhod gtpase cycle 0.3316785843478821 0.561964807085774 0.5741399972188859 1.0 0.8557245818421612 30 Q14739,P49257,Q9H0H5,P42166,P50402,O15173,O00459,Q9Y2U8,P42167 9
Tight junction interactions 0.4756387403446369 0.5516293792349369 0.5812023034895795 1.0 0.8589183669388126 2 Q9Y624 1
Rnd1 gtpase cycle 0.3736052211602876 0.5510465333871967 0.5816017758613308 1.0 0.8589183669388126 17 Q9Y2U8,Q9ULH0,P51648,O00459,Q14254,P38159 6
Miro gtpase cycle 0.5175886448615383 0.5507738346228213 0.581788722905136 1.0 0.8589183669388126 5 Q8IXI1,O95140,Q8IWA4 3
Plasma lipoprotein assembly remodeling and clearance 0.3664196336437696 0.5488064896766642 0.5831382561853213 1.0 0.8591039996686162 18 Q8WTV0,O15118,Q9BU23,P61916 4
Sumoylation of rna binding proteins 0.3206272952357028 0.5412899990627893 0.5883077126665233 1.0 0.8640000298993711 34 Q7Z3B4,Q8NFH5,Q99567,Q8N1F7,P61978,Q9BTX1,O15504 7
Receptor mediated mitophagy 0.5352154531946522 0.5331464305945387 0.5939322204952135 1.0 0.8671887147719537 3 P19784,P67870 2
Nicotinate metabolism 0.5348685158240848 0.5318895203542955 0.594802515901276 1.0 0.8671887147719537 3 P43490 1
Signaling by fgfr1 in disease 0.4127355868118042 0.5254561161211759 0.5992661522485059 1.0 0.8722439615292923 11 Q92614,O95684,O95429 3
Collagen formation 0.3873427308549365 0.5248465556779431 0.5996898645903332 1.0 0.8722439615292923 14 P13674,Q32P28,P07237,O75718,O60568 5
Regulation of commissural axon pathfinding by slit and robo 0.4649435531788531 0.5087186111678375 0.6109494751494058 1.0 0.8811984129245026 2 O94813 1
Rhot1 gtpase cycle 0.4622697563874107 0.4981863936905814 0.6183526717233683 1.0 0.8858848480608256 2 Q8IXI2 1
Adora2b mediated anti inflammatory cytokines production 0.4249770468783656 0.4970549711550084 0.6191502870516392 1.0 0.8861233466060158 9 P08754,P10644,Q9UBI6,P63096 4
Metabolism of cofactors 0.5033117086799284 0.4948748875490147 0.6206884381657436 1.0 0.8874201295159918 5 P00374 1
Chaperone mediated autophagy 0.4405765022137061 0.4912827984046237 0.6232264444246192 1.0 0.8898672429784622 7 P08670 1
Myoclonic epilepsy of lafora 0.4598930481283523 0.4888932041826543 0.6249173071921479 1.0 0.8898672429784622 2 P46976 1
Trna modification in the mitochondrion 0.4391812035431872 0.4848996630544833 0.6277475214264043 1.0 0.8899280155607909 7 Q7L0Y3,O75648,O15091,Q969Y2 4
Plasma lipoprotein clearance 0.3788430893062064 0.4732024192030038 0.6360687719797906 1.0 0.894470456929596 14 Q8WTV0,O15118 2
Diseases associated with glycosylation precursor biosynthesis 0.4365107094820707 0.4727318983282819 0.6364044659690409 1.0 0.894470456929596 7 P10619 1
Hcmv early events 0.3000914752585478 0.472374203834985 0.6366597137342145 1.0 0.894470456929596 46 Q8NFH5,Q99567,P04350,Q9BUF5,P83916,Q8N1F7,Q9BVA1,Q9BTX1,Q13885,O15504 10
Interleukin receptor shc signaling 0.5180653973905464 0.4721721984584561 0.6368038821213182 1.0 0.894470456929596 3 O00459 1
Assembly of the hiv virion 0.5167904903417551 0.4677387442821583 0.6399714306082114 1.0 0.8958323913997296 3 Q9H9H4,Q99816 2
Regulation of pten stability and activity 0.3007472096264615 0.4556014581039905 0.6486765944378681 1.0 0.9044110611626284 41 P28072,P61289,P46934,Q9UNM6,P20618,P49721 6
G beta gamma signalling through cdc42 0.5123328380386347 0.452352152310699 0.6510153107627432 1.0 0.9049757389216748 3 Q9UBI6,P60953 2
G protein beta gamma signalling 0.5123328380386347 0.452352152310699 0.6510153107627432 1.0 0.9049757389216748 3 Q9UBI6,P60953 2
Cargo trafficking to the periciliary membrane 0.3305479156596364 0.4499251299484915 0.6527644268297235 1.0 0.905583734856634 22 O43924,Q10713 2
Activation of rac1 downstream of nmdars 0.4483065953654341 0.4445612549821224 0.6566368525319148 1.0 0.905583734856634 2 Q14155 1
Syndecan interactions 0.4302290984826065 0.4443757914596251 0.6567709129702515 1.0 0.905583734856634 7 Q9Y296,P12814,P05556,P06756,P17252,O14936 6
Beta oxidation of very long chain fatty acids 0.5082587361594686 0.4328201701892335 0.6651454187791648 1.0 0.9101989941188572 4 Q15067 1
Synthesis of pips at the golgi membrane 0.4274400718802319 0.4319108446920189 0.6658062125306361 1.0 0.9102160880165656 7 Q9BTU6,Q10713 2
Hedgehog on state 0.2944100042464013 0.4253658067018787 0.6705700283368807 1.0 0.9131719881522604 43 P28072,P61289,P48729,Q9UNM6,P20618,P49721,Q96J02 7
Rnd2 gtpase cycle 0.3340825328822969 0.4213943704841704 0.6734671292598104 1.0 0.915341577425725 20 P51648,Q07065,O00459 3
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.4541869953967658 0.4115286023884009 0.6806849726401165 1.0 0.9192017326847798 6 Q15067 1
Signaling by erbb2 in cancer 0.4780176280884358 0.3999213010301483 0.689214482652996 1.0 0.9257107226061142 5 Q16543 1
Signaling by erbb2 ecd mutants 0.4780176280884358 0.3999213010301483 0.689214482652996 1.0 0.9257107226061142 5 Q16543 1
Citric acid cycle tca cycle 0.3379929568770058 0.3993060971089534 0.6896676751039854 1.0 0.9257107226061142 19 P48735,Q6P587,P21912,Q13423 4
Activation of rac1 0.4488399762046438 0.3903314443304749 0.6962914744828621 1.0 0.928742124678021 6 Q13177,Q9Y6N7,Q16512,O96013,O94813 5
Pi3k akt signaling in cancer 0.3953500076797722 0.389781059881188 0.6966984502850107 1.0 0.928742124678021 10 O00459,P84095 2
Phase ii conjugation of compounds 0.312996889130207 0.3858492091926727 0.699608348313892 1.0 0.930161099462788 29 Q9NUJ1,Q8TB61,O43708,P21964 4
P75ntr negatively regulates cell cycle via sc1 0.4284016636957903 0.3725282267955106 0.7094995999245848 1.0 0.939479009215498 2 Q92769 1
Regulation of runx3 expression and activity 0.2965288392897232 0.362397554974363 0.7170549663563588 1.0 0.9435287467332032 37 P28072,P61289,P20618,Q9UNM6,P49721 5
G1 s specific transcription 0.3690993563879432 0.3380078191855369 0.7353572953635188 1.0 0.9557707632396716 12 P00374 1
Unblocking of nmda receptors glutamate binding and activation 0.4595710182379604 0.3345941306332078 0.7379312730425953 1.0 0.9557707632396716 5 Q14168,P07196 2
Negative regulation of nmda receptor mediated neuronal transmission 0.4595710182379604 0.3345941306332078 0.7379312730425953 1.0 0.9557707632396716 5 Q14168,P07196 2
Ras activation upon ca2 influx through nmda receptor 0.4595710182379604 0.3345941306332078 0.7379312730425953 1.0 0.9557707632396716 5 Q14168,P07196 2
Long term potentiation 0.4595710182379604 0.3345941306332078 0.7379312730425953 1.0 0.9557707632396716 5 Q14168,P07196 2
Antigen processing cross presentation 0.2875340854076436 0.3334898134691338 0.7387645774867253 1.0 0.9559681721579376 55 P28072,P62191,P61289,Q03519,Q9UNM6,Q9UIQ6,P49721,P20618,Q03518 9
Transcriptional regulation by runx3 0.2875056317591932 0.3266299029828229 0.7439478236798482 1.0 0.9600209048221572 41 P28072,P61289,P20618,Q9UNM6,P49721 5
Signaling by gpcr 0.2850289995010924 0.3227629470975197 0.7468747762705308 1.0 0.9629129346958908 45 P42892,Q8N2K0,P04083,P22466,Q9NZJ7,P07602,P52292,O00459 8
Platelet activation signaling and aggregation 0.2847971545497065 0.3213601997740653 0.747937440770047 1.0 0.9633885271251816 61 Q6UXV4,O94919,P07602,Q9NTK5,Q8N2K0,Q8NBX0,P13473,Q12846,Q96JJ7,Q06481,P62993,Q9NUQ9,O00459,P46108,Q9BWS9,O43852,P84095,Q9NZJ7,Q92520 19
Signaling by cytosolic fgfr1 fusion mutants 0.3943717996728068 0.3170934978384649 0.7511726584800957 1.0 0.9633885271251816 8 Q92614,O95684 2
Mecp2 regulates neuronal receptors and channels 0.4289113622843508 0.314134045537682 0.7534192327517446 1.0 0.9633885271251816 6 P18031,P51608,Q92769,Q96ST3,Q13451 5
Cd28 dependent vav1 pathway 0.4487065120428281 0.2979095673891985 0.7657721856073181 1.0 0.965070482670611 5 Q16512,P60953,P62993,Q13177 4
Maturation of sars cov 1 spike protein 0.4668731032617627 0.2977049608953375 0.7659283567781747 1.0 0.965070482670611 4 P27824 1
Sensory processing of sound 0.3210774796981428 0.2844229195877159 0.7760862966805382 1.0 0.9711454193756468 19 P23634 1
Regulation of kit signaling 0.4397859054415792 0.2688766673040596 0.7880245927811778 1.0 0.9763148469928076 5 P07948,P07947,P17252,P62993 4
Ret signaling 0.3884614769809679 0.2673780190896271 0.7891781217773013 1.0 0.9763148469928076 7 O00459 1
Thromboxane signalling through tp receptor 0.4556277216961976 0.2643220368279254 0.7915317810018097 1.0 0.9763148469928076 4 P29992,Q9UBI6 2
Degradation of gli1 by the proteasome 0.2794279888775594 0.2629451460397888 0.7925928587590976 1.0 0.9763148469928076 42 P28072,P61289,Q9UNM6,P20618,P49721,Q96J02 6
Formation of tubulin folding intermediates by cct tric 0.353348967615413 0.2559142653152572 0.7980170392097883 1.0 0.9768229494773696 12 Q9BVA1,Q13885,P04350 3
Signaling by interleukins 0.2504047122587487 0.2533448412519522 0.800001747724373 1.0 0.9783993500043726 110 P09601,P28072,P62191,P04083,P61289,P22626,Q9UNM6,P49721,P08670,Q12846,P78417,Q07820,P11233,P07237,P62993,P28070,Q13126,O00459,P27824,O14979,P20618,P52597 22
Sars cov infections 0.2779710158039962 0.249496130033592 0.8029770340630455 1.0 0.9785052514423525 62 Q9H0U3,P21964,P07437,P48729,Q10472,P05023,Q99720,Q15185,P46977,P27824 10
Sumoylation of sumoylation proteins 0.2976533824681217 0.2494827647022763 0.8029873712760176 1.0 0.9785052514423525 28 Q8NFH5,Q99567,Q8N1F7,Q9BTX1,O15504 5
Sumoylation of ubiquitinylation proteins 0.2976533824681217 0.2494827647022763 0.8029873712760176 1.0 0.9785052514423525 28 Q8NFH5,Q99567,Q8N1F7,Q9BTX1,O15504 5
Regulation of glucokinase by glucokinase regulatory protein 0.2976533824681217 0.2494827647022763 0.8029873712760176 1.0 0.9785052514423525 28 Q8NFH5,Q99567,Q8N1F7,Q9BTX1,O15504 5
Rho gtpases activate ktn1 0.4098750743605004 0.2460456505762528 0.8056468944171804 1.0 0.9793318093175076 6 P63000,Q07866,P60953,Q86UP2,P84095 5
Translation of sars cov 2 structural proteins 0.320669603786927 0.2443020933396356 0.8069968623378827 1.0 0.9793767289852076 18 Q9H0U3,Q10472,P48729,P46977,P27824 5
Inactivation of cdc42 and rac1 0.4485731272294775 0.2441960693914062 0.8070789711081803 1.0 0.9793767289852076 4 O94813,Q9Y6N7,P60953 3
Signaling by ntrk3 trkc 0.4470256557636327 0.2398683506857492 0.8104323171395957 1.0 0.9817488984158692 4 P62993 1
Flt3 signaling in disease 0.3802467171322444 0.2354268180434744 0.8138774731559777 1.0 0.983421256632356 7 Q92614 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.3336323803209776 0.2353795281454047 0.8139141739364657 1.0 0.983421256632356 15 Q9BVA1,Q13885,P04350 3
Interleukin 12 signaling 0.2966867850406217 0.2322282020122881 0.8163607743909944 1.0 0.9842827157219596 27 O14979,P78417,P11233,P22626,P07237,P52597,Q13126 7
Atf6 atf6 alpha activates chaperone genes 0.438930163447253 0.2299476765933105 0.8181324282389792 1.0 0.9842827157219596 3 P14625,P25208 2
Atf6 atf6 alpha activates chaperones 0.438930163447253 0.2299476765933105 0.8181324282389792 1.0 0.9842827157219596 3 P14625,P25208 2
Negative regulation of notch4 signaling 0.2794765140452356 0.227554853284455 0.8199923209804743 1.0 0.9856757009046112 39 P28072,P61289,P20618,Q9UNM6,P49721 5
Rho gtpase cycle 0.2515761044371604 0.2235286229190903 0.8231241087487178 1.0 0.988593882534816 166 Q14739,P07910,P42166,P50402,O15173,Q9Y2I1,P30519,Q9UQB8,Q86VI3,P51648,Q15904,Q9Y512,Q13190,P51572,P62995,P08670,Q5T8D3,P27105,O75955,P49257,O95202,Q96HY6,P62993,O00459,Q96CS3,P38159,Q86XL3,Q13505,Q16543,Q9NYL9,P84095,Q07065,P42167 33
Vasopressin regulates renal water homeostasis via aquaporins 0.4141988154647624 0.1915899514510858 0.8480634142796168 1.0 1.0 5 P10644 1
Glucagon signaling in metabolic regulation 0.4141988154647624 0.1915899514510858 0.8480634142796168 1.0 1.0 5 P10644 1
Notch hlh transcription pathway 0.428656361474425 0.1909882995878393 0.848534760003542 1.0 1.0 4 Q04721,Q92769,Q13573 3
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.4286563614744209 0.1909882995878291 0.84853476000355 1.0 1.0 4 Q92769,Q96ST3,P04179 3
Glutamate neurotransmitter release cycle 0.4245554723756617 0.1807243301887738 0.8565839605095638 1.0 1.0 4 Q96QD8 1
Negative regulators of ddx58 ifih1 signaling 0.3610638697773898 0.1800952719170158 0.8570777743858591 1.0 1.0 8 Q86UT6,Q86VP1,Q96J02 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3548110807185787 0.1740628817130337 0.8618160439421612 1.0 1.0 9 Q14168,P07196,Q15418 3
Bile acid and bile salt metabolism 0.4218192627823957 0.1740116194102945 0.8618563305784255 1.0 1.0 4 P51659,Q96SU4,P22307 3
Synthesis of bile acids and bile salts 0.4218192627823957 0.1740116194102945 0.8618563305784255 1.0 1.0 4 P51659,Q96SU4,P22307 3
Pi metabolism 0.2975659519595178 0.1697757470737549 0.8651865010395654 1.0 1.0 20 Q10713,Q8IY17,O00459,Q9BTU6 4
Cytosolic sulfonation of small molecules 0.4176005973767338 0.1638772130875007 0.8698278058873954 1.0 1.0 4 Q8TB61 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3471669209939856 0.1633613787191429 0.8702339096589753 1.0 1.0 10 Q9UJX2,Q96DE5,Q9UJX3 3
Rnd3 gtpase cycle 0.3016966767550665 0.1602266789564511 0.8727025141183895 1.0 1.0 19 Q9Y2I1,P38159,Q9NYL9,O00459,Q07065,Q14254,Q9Y2U8 7
Circadian clock 0.3444338641191454 0.1516656947066172 0.8794506157614368 1.0 1.0 10 P43490 1
Interleukin 12 family signaling 0.2820175474765812 0.1493819952773347 0.8812522180076781 1.0 1.0 30 O14979,P11233,P22626,P07237,P52597,Q13126,P27824 7
Ripk1 mediated regulated necrosis 0.330684542298732 0.1455088346988541 0.8843091409063968 1.0 1.0 12 O75955,Q8WUM4,Q16543,O00560,Q14254 5
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2675368518876081 0.1407967684119709 0.8880304960683474 1.0 1.0 41 P28072,P61289,Q9UNM6,P20618,P49721,Q96J02 6
Phosphorylation of emi1 0.4069560047562269 0.1394850559876018 0.8890668640932926 1.0 1.0 4 P53350,P06493,Q12834 3
Neurotransmitter release cycle 0.3497225094638129 0.1270309729270275 0.8989158842727367 1.0 1.0 7 O94925,Q96QD8,O14936 3
Metalloprotease dubs 0.3959571938168788 0.1160892730128785 0.9075817902278498 1.0 1.0 4 Q9NWV8,Q15018,Q9NXR7 3
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2807498477610434 0.1035526184323024 0.9175243904417294 1.0 1.0 25 O14979,P78417,P11233,P22626,P52597,Q13126 6
Irs mediated signalling 0.3847026056507582 0.0940829725706251 0.9250432462990752 1.0 1.0 4 O00459 1
Rab geranylgeranylation 0.2790056612977633 0.0916996568815882 0.9269366700133836 1.0 1.0 25 Q9ULC3,P61020,Q9NP72,P61019,Q969Q5,P20337,P62820,P61026,P51151,Q9H0U4 10
Mitotic metaphase and anaphase 0.2442843065558909 0.0914189894134093 0.9271596735589172 1.0 1.0 135 Q7Z3B4,Q14739,Q8NFH5,P42166,P50402,Q8N1F7,P28072,Q8NBT2,P62191,P61289,Q9BUF5,Q12834,P04350,Q9UNM6,P49721,Q96DE5,Q15005,P50748,Q14674,Q9BVA1,P28070,Q9Y2U8,Q92674,Q9UJX3,Q86XL3,Q92973,Q9UJX2,Q9BTX1,P20618,Q13885,P02545,P42167 32
Met activates rap1 and rac1 0.3741011596188286 0.0906503614887037 0.9277704139495244 1.0 1.0 5 P62993 1
Scf skp2 mediated degradation of p27 p21 0.2616171293361681 0.0884954175761046 0.929482926295964 1.0 1.0 41 P28072,P61289,P20618,Q9UNM6,P49721 5
Mhc class ii antigen presentation 0.2628852534816749 0.0854594554889003 0.931896127341142 1.0 1.0 51 Q13561,Q9BUF5,O75935,P04350,Q9BVA1,Q13885,P53634,Q9UJW0,P10619 9
Hcmv infection 0.2632386912570296 0.0809597398759125 0.9354739702831238 1.0 1.0 57 Q8NFH5,Q99567,Q9BUF5,P04350,P83916,Q8N1F7,P61978,Q9BVA1,Q9BTX1,Q13885,O15504 11
Degradation of axin 0.2641859155274142 0.0786700711633953 0.9372950514288132 1.0 1.0 37 P28072,P61289,P20618,Q9UNM6,P49721 5
Ra biosynthesis pathway 0.3736758590237782 0.0744318058455971 0.9406668015810448 1.0 1.0 4 Q9HBH5,Q8NBN7 2
Arms mediated activation 0.3589690755863855 0.0722687918808747 0.9423880002065634 1.0 1.0 3 P46108 1
Clec7a dectin 1 induces nfat activation 0.2941176470588335 0.0664392894376187 0.9470280908405628 1.0 1.0 2 O43865 1
Metabolism of polyamines 0.261821489415713 0.0658734421319205 0.9474785847536936 1.0 1.0 38 P28072,P61289,P20618,Q9UNM6,P49721 5
Regulation of runx1 expression and activity 0.2932263814616857 0.0655197137911784 0.947760210723255 1.0 1.0 2 Q9HCE1 1
Pre notch processing in the endoplasmic reticulum 0.3518573551263022 0.0629297180410671 0.949822470162206 1.0 1.0 3 Q04721,Q9H488 2
Postmitotic nuclear pore complex npc reformation 0.2753711678670864 0.0620107857405339 0.9505542427544162 1.0 1.0 23 Q8NFH5,Q8N1F7,Q9BTX1,Q92973 4
Downregulation of erbb2 signaling 0.3461970024144406 0.0604390271709743 0.9518059762671004 1.0 1.0 6 Q16543 1
Cdc42 gtpase cycle 0.2631725231786131 0.0594658167504794 0.9525810915573412 1.0 1.0 35 Q14739,Q9UQB8,Q9H0H5,P42166,Q86VI3,O00459,P27105,P42167 8
Negative regulation of met activity 0.3263870944292191 0.0593223069186211 0.9526953940486458 1.0 1.0 8 P40818,P62993 2
Reactions specific to the complex n glycan synthesis pathway 0.2863933452168849 0.0588896232944331 0.953040023119914 1.0 1.0 2 P04066 1
N glycan antennae elongation in the medial trans golgi 0.2863933452168849 0.0588896232944331 0.953040023119914 1.0 1.0 2 P04066 1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.3602848545727581 0.0530971343763154 0.957654514670402 1.0 1.0 4 O00459 1
Eph ephrin mediated repulsion of cells 0.2980485288371779 0.0391225169871267 0.9687927087501264 1.0 1.0 14 P49768 1
E2f mediated regulation of dna replication 0.2995955591361012 0.0368398000407289 0.9706127397303252 1.0 1.0 13 Q9UJA3 1
Glutamate and glutamine metabolism 0.3165724486759969 0.0306722192463351 0.9755309465644748 1.0 1.0 7 Q96C36,P32322,O94925,P54886,P04181,P00367 6
Signaling by kit in disease 0.3323494586232928 0.029978576483122 0.9760841389802776 1.0 1.0 6 O00459 1
Synthesis of pips at the er membrane 0.3200594353640438 0.0297870962131127 0.9762368499317478 1.0 1.0 3 P42356,Q9NTJ5 2
Ldl clearance 0.3030995738028429 0.0268258920493816 0.9785986017774416 1.0 1.0 12 O15118 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3393975425323697 0.0251098996486715 0.979967303895189 1.0 1.0 5 O00459 1
Copii mediated vesicle transport 0.2650854037509421 0.0246894757351354 0.980302649669949 1.0 1.0 30 P49257,Q12907,Q15363,Q13190,P49755,P53634 6
Asymmetric localization of pcp proteins 0.2565351120053426 0.0230621327901122 0.9816007113023582 1.0 1.0 38 P28072,P61289,P20618,Q9UNM6,P49721 5
Lipophagy 0.3373959571938068 0.022884763924728 0.9817421938407236 1.0 1.0 4 P54619,P54646,O60664 3
Class b 2 secretin family receptors 0.3031203566121864 0.017324572161801 0.9861776827932678 1.0 1.0 3 Q9UBI6,Q9Y3E5 2
Anti inflammatory response favouring leishmania parasite infection 0.2900834934269688 0.0144929886992748 0.9884366728848668 1.0 1.0 15 P10644,O43865,P78536,P63096 4
Cross presentation of soluble exogenous antigens endosomes 0.2550714449856591 0.0114576689236498 0.9908583028810224 1.0 1.0 38 P28072,P61289,P20618,Q9UNM6,P49721 5
Factors involved in megakaryocyte development and platelet production 0.2530797448158929 0.0109754595844773 0.9912430260620702 1.0 1.0 47 Q86Y91,Q9BUF5,P04350,Q9BVA1,P10644,Q13885 6
Vegfr2 mediated cell proliferation 0.2909361069836577 0.0102759701522674 0.991801106362953 1.0 1.0 3 P17252,O43865 2
Fcgr3a mediated il10 synthesis 0.3074581052426937 0.0046770838608908 0.9962682406032632 1.0 1.0 8 P10644 1
Gastrin creb signalling pathway via pkc and mapk 0.3178328204311073 0.0020776783215571 0.9983422537375934 1.0 1.0 6 P62993,Q15418 2
Regulation of ras by gaps 0.2538441419613641 0.0018143511859353 0.9985523579951094 1.0 1.0 38 P28072,P61289,P20618,Q9UNM6,P49721 5
Degradation of dvl 0.2538441419613641 0.0018143511859353 0.9985523579951094 1.0 1.0 38 P28072,P61289,P20618,Q9UNM6,P49721 5