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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +4 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +6 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/basic/plot_4.png +3 -0
- interpro_conserved_site/basic/plot_5.png +3 -0
- interpro_conserved_site/basic/plot_6.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +4 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +41 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_17.png +3 -0
- interpro_domain/basic/plot_18.png +3 -0
- interpro_domain/basic/plot_19.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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oid sha256:4298b77f21e5c38faeef08c4971beb4e4253978e0ef6a5ebe2b3157040c926c4
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3364,
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"annotations_size": 55,
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"title": "Average number of proteins per term",
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"value": 2.6545454545454548
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C154/C154_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine/threonine-protein kinase, active site [IPR008271] 0.377200140512782 0.9005429802260675 0.3678313632422567 0.9999999999888874 0.6384186144535752 46 P54646,P19525,P49841,O14965,Q96KB5,Q99986,O75116,Q96SB4,Q16513,P33981,Q9H4A3,P48729,O14976,Q99570,P24941,O96017,Q96PY6,P21127 18
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ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.5279595478881738 0.1149290580639672 0.9085013526934732 1.0 0.9427844226064344 2 P53597 1
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Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4812611540749644 0.0681162063827008 0.9456931294923824 1.0 0.9632059652237228 2 Q9NQ88 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP8", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK1", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["AURKA", "CDK11B", "CDK2", "CHEK2", "CSNK1A1", "EIF2AK2", "GAK", "GSK3B", "NEK1", "PBK", "PIK3R4", "PKN2", "PRKAA2", "ROCK2", "SRPK1", "SUCLG1", "TIGAR", "TTK", "VRK1", "WNK1"]}
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interpro_binding_site/advanced/idx2term.json
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interpro_binding_site/basic/idx2term.json
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{"0": "Protein kinase, ATP binding site [IPR017441]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/consensus.joblib
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oid sha256:9ecd76bf389d425764280962ba73252fe66f9fa124d6794c9c312fc3b009f51d
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size 74997
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3364,
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"annotations_size": 30,
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"title": "Average number of proteins per term",
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"value": 4.8
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C154/C154_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Protein kinase, ATP binding site [IPR017441] 0.3016026689022767 0.3582247297828073 0.7201751419078541 1.0 0.9665683589667338 43 O96013,P54646,P19525,P49841,O14965,Q99986,O75116,Q96SB4,Q16513,P33981,P41240,P48729,O95747,P24941,Q96PY6 15
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.6255205234979225 0.2907000862328378 0.7712807056414612 1.0 0.9665683589667338 2 Q9H0C8 1
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Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.6115407495538465 0.2589290434383782 0.7956899887323705 1.0 0.9665683589667338 2 P50579 1
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Hexokinase, binding site [IPR019807] 0.5464009518144047 0.1398317488577909 0.8887929277664885 1.0 0.9835541264573032 2 P52789 1
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Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.4396192742415238 0.0431594484400595 0.965574430404602 1.0 0.9835541264573032 2 Q9Y617 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CETN2", "CIB1", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK3", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AURKA", "CDK2", "CSK", "CSNK1A1", "EIF2AK2", "GSK3B", "HK2", "ILKAP", "METAP2", "NEK1", "OXSR1", "PAK4", "PKN2", "PRKAA2", "PSAT1", "ROCK2", "SRPK1", "TTK", "VRK1"]}
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}
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interpro_conserved_site/basic/idx2term.json
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Ubiquitin specific protease, conserved site [IPR018200]", "2": "Zinc finger, RING-type, conserved site [IPR017907]", "3": "FERM conserved site [IPR019747]", "4": "Zinc finger, PHD-type, conserved site [IPR019786]", "5": "ATPase, AAA-type, conserved site [IPR003960]", "6": "Kinesin motor domain, conserved site [IPR019821]"}
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interpro_conserved_site/basic/plot_5.png
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interpro_conserved_site/basic/plot_6.png
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interpro_conserved_site/consensus.joblib
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oid sha256:e3a5e5b09fceabd0790e8b83f90f6d943e98d33c2a95e9f2ac2be8497dc2b066
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.674600035364849 0.0074818451194818 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.148254609278584e-05 1.7047530342538662e-08 3.684086308322036e-08 2.2585304294532336e-06
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Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 1 5 2.1871858857342583 0.0287289568242634 1.8349514563106797 4.495145631067961 -0.0268416016144192 0.3268992301433215 1.18113888908689 0.4999764345469411 1.4254920509394828 0.309635855483207 1.0 0.0002150789234385 0.0008792489757495 0.0055694485300755 0.0213301790272909
|
| 4 |
+
Acyl-CoA dehydrogenase, conserved site [IPR006089] 1 7 2.1246905370664955 0.03361244358577 2.924757281553398 6.072815533980583 -0.8305136503397285 0.3058599896865968 1.8252992012537188 0.6679477589532989 1.090766824396359 0.268185473646236 1.0 0.0005968088999726 0.0024164244761899 0.0148625463558957 0.0542215392640632
|
interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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| 3 |
+
"signature_size": 3364,
|
| 4 |
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"annotations_size": 286,
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| 5 |
+
"title": "Average number of proteins per term",
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| 6 |
+
"value": 2.800699300699301
|
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+
}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C154/C154_val_log2fc"}
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interpro_conserved_site/result.tsv
ADDED
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.919858298982414 2.674600035364849 0.0074818451194818 0.8832654484399379 0.3095036646639985 8 P28072,P28074,Q99436,P28070,P49721 5
|
| 3 |
+
Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.9159289751272052 2.1871858857342583 0.0287289568242634 0.9997604665482144 0.3297154539030924 5 P48735 1
|
| 4 |
+
Acyl-CoA dehydrogenase, conserved site [IPR006089] 0.8167290186248083 2.1246905370664955 0.03361244358577 0.9999433395340444 0.369736879443471 7 P11310 1
|
| 5 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.6284377695789387 1.876828179978334 0.0605416468568622 0.9999999825025712 0.4161900512543395 14 Q96K76,Q96RU2,Q9UPU5,Q8TEY7,P51784 5
|
| 6 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.556633300473814 1.6204389958617582 0.1051380087909845 0.999999999999984 0.5369548306110997 16 Q96T88,Q9UPN9,P22681,O15164,Q14527,Q5VTR2 6
|
| 7 |
+
Sugar transporter, conserved site [IPR005829] 0.9530041641879856 1.3973029999732989 0.1623224740887536 1.0 0.6189897011917807 2 P11166 1
|
| 8 |
+
AMP-binding, conserved site [IPR020845] 0.6605099995912662 1.322067979479731 0.186145515232599 1.0 0.6456686508806954 6 Q86V21,Q4G176 2
|
| 9 |
+
Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.735145383771847 1.2747835969758643 0.2023858480845248 1.0 0.6456686508806954 4 P42356,O00443 2
|
| 10 |
+
Bromodomain, conserved site [IPR018359] 0.5104652520747952 1.1854337300184103 0.2358460020978903 1.0 0.6890581124373937 13 Q8WWQ0,Q15059,P25440 3
|
| 11 |
+
Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.887864366448543 1.1495288294880928 0.2503379860468411 1.0 0.6937619863542819 2 P24534 1
|
| 12 |
+
Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.6899732176869848 1.100816634813295 0.2709764703529722 1.0 0.6949499704745931 4 Q14155,Q7Z628 2
|
| 13 |
+
Ubiquitin interacting motif [IPR003903] 0.6837308906174518 1.07685066048206 0.2815469885057426 1.0 0.7063371816898456 4 P55036,O75886 2
|
| 14 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.8223742933650575 0.996734024150572 0.3188936299479254 1.0 0.7238379219452912 3 P26583,O15347 2
|
| 15 |
+
Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.8444378346222527 0.987126909085606 0.3235804275575324 1.0 0.7286929313500338 2 P06730 1
|
| 16 |
+
Guanylate kinase, conserved site [IPR020590] 0.5532112906251132 0.9804601881476508 0.3268590122733932 1.0 0.7303256055483629 7 Q14168,Q12959 2
|
| 17 |
+
Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.7635336109458741 0.6978528294058309 0.4852692365650719 1.0 0.8600179015618323 2 P06737 1
|
| 18 |
+
ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.3760958655240209 0.6729518426361177 0.5009779287180811 1.0 0.8600179015618323 20 P41208,Q14240 2
|
| 19 |
+
Actinin-type actin-binding domain, conserved site [IPR001589] 0.3882519754484347 0.6602333794682838 0.5091040748298741 1.0 0.8600179015618323 16 P46939,P11532,P21333 3
|
| 20 |
+
DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.7477691850089301 0.6446007717397372 0.519185934639439 1.0 0.8632975424818579 2 P09884 1
|
| 21 |
+
Histidine triad, conserved site [IPR019808] 0.7379535990481887 0.6121214351048312 0.5404574166100637 1.0 0.8883380525889553 2 Q9BX68 1
|
| 22 |
+
FERM conserved site [IPR019747] 0.4166533589679377 0.5989040197250661 0.5492368907464735 1.0 0.8912796519814257 11 P26038,P11171,P15311,Q9HCM4,Q9Y4F1 5
|
| 23 |
+
Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.6955093221793411 0.5773648339245574 0.563693024747363 1.0 0.8912796519814257 3 Q9H3P7 1
|
| 24 |
+
Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3684236773252938 0.4871863535180654 0.6261262751857846 1.0 0.9344587312687962 14 P07814,Q9NSE4,P26640,P23381 4
|
| 25 |
+
Cadherin conserved site [IPR020894] 0.4542437955228677 0.4778009611307915 0.6327918770121708 1.0 0.9368571634261036 6 Q14126,Q02487,Q14517 3
|
| 26 |
+
Zinc finger, PHD-type, conserved site [IPR019786] 0.3391129399958007 0.449804018268626 0.652851760203079 1.0 0.9410031371170968 18 Q9UPN9,Q14839,O95696,Q13263,O15164,P29375 6
|
| 27 |
+
Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.6320642474717447 0.3062848939310921 0.7593877397980751 1.0 0.9595671046907496 2 P12955 1
|
| 28 |
+
ATPase, AAA-type, conserved site [IPR003960] 0.3009405372887176 0.2788073424067198 0.7803926793858642 1.0 0.9595671046907496 19 P62333,Q15645,Q6PL18,Q8NB90,Q9UN37,O75351,P62195 7
|
| 29 |
+
AT hook, DNA-binding motif [IPR017956] 0.5673906575424075 0.241031843996465 0.8095304360307463 1.0 0.9606875713891844 3 Q9UIF9,P17096 2
|
| 30 |
+
Dynein light chain, type 1/2, conserved site [IPR019763] 0.5963712076145222 0.2268755393392384 0.8205205229038284 1.0 0.9617576620921924 2 Q96FJ2 1
|
| 31 |
+
Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.5809042236763928 0.1968647312212763 0.8439333939454503 1.0 0.9633266274366924 2 Q00796 1
|
| 32 |
+
Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.3049512645472202 0.1823576439836396 0.8553020636161399 1.0 0.9633266274366924 12 Q13356,Q9H2H8,Q13427 3
|
| 33 |
+
Annexin repeat, conserved site [IPR018252] 0.3559062966416454 0.1717054367806025 0.8636691113665393 1.0 0.9633266274366924 6 P09525,P04083 2
|
| 34 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.2851419488789086 0.1700034767294904 0.8650074024184424 1.0 0.9633266274366924 15 Q86WJ1 1
|
| 35 |
+
Kinesin motor domain, conserved site [IPR019821] 0.288824743498891 0.1668777846886756 0.8674662132727611 1.0 0.9633266274366924 14 P52732,Q14807,Q15058,O95239,Q99661,Q12756,Q02241 7
|
| 36 |
+
DnaJ domain, conserved site [IPR018253] 0.2839845014429975 0.1226127508154674 0.902413756945882 1.0 0.987412943471988 12 P31689,Q96EY1,Q5F1R6 3
|
| 37 |
+
ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.5279595478881738 0.1149290580639672 0.9085013526934732 1.0 0.9879520413320658 2 P53597 1
|
| 38 |
+
Ribosomal protein L24e, conserved site [IPR023442] 0.501189767995254 0.0853874584302834 0.9319533634703948 1.0 1.0 2 Q9UHA3 1
|
| 39 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.3867896459387169 0.0276923859373012 0.9779074965181218 1.0 1.0 3 Q96CW1,Q9BXS5 2
|
| 40 |
+
Oxysterol-binding protein, conserved site [IPR018494] 0.2898809523809545 0.0221684854118582 0.9823135564081436 1.0 1.0 4 Q9BZF1,P22059,Q96SU4 3
|
| 41 |
+
Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.3259964306960117 0.0216488650302828 0.9827280539941226 1.0 1.0 2 P09972 1
|
interpro_conserved_site/selections.json
ADDED
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, NFYB/HAP3, conserved site [IPR003956]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD3", "BRD4", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC40", "CDH2", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPA1", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA6", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAGI3", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF2", "NFYB", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RING1", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SHPRH", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM2", "STMN1", "STOM", "STRN", "STRN4", "STX12", "STX17", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TATDN1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["AACS", "ACADM", "ACBD3", "ACSF3", "ALDOC", "ANXA1", "ANXA4", "AP1M1", "AP2M1", "ARHGEF7", "ATAD2", "BAZ2A", "BRD1", "BRD2", "BRD3", "CBL", "CETN2", "CHD1L", "CHD4", "DLG1", "DMD", "DNAJA1", "DNAJA3", "DNAJC21", "DSC2", "DSG2", "DYNLL2", "EEF1B2", "EIF4A2", "EIF4E", "EPB41", "EPB41L5", "EPRS", "EZR", "FARP1", "FAT1", "FLNA", "HINT2", "HLTF", "HMGA1", "HMGB2", "HMGB3", "IARS2", "IDH2", "KDM5A", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2C", "KIF4A", "MPP2", "MSN", "NET1", "OSBP", "OSBPL8", "OSBPL9", "PEPD", "PHIP", "PI4KA", "PIK3C2A", "POLA1", "PPIG", "PPIL2", "PPIL3", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC5", "PSMC6", "PSMD4", "PYGL", "RNF20", "RSL24D1", "SLC2A1", "SORD", "SPATA5", "STAM2", "SUCLG1", "TRIM24", "TRIM28", "TRIM33", "TRIP13", "UHRF1", "USP11", "USP24", "USP28", "USP33", "USP47", "UTRN", "VARS1", "VPS4A", "VPS4B", "WARS"]}
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{"0": "Calponin homology domain [IPR001715]"}
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{"0": "Calponin homology domain [IPR001715]", "1": "HECT domain [IPR000569]", "2": "Ubiquitin specific protease domain [IPR028889]", "3": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "4": "High mobility group box domain [IPR009071]", "5": "Zinc finger, RING-type [IPR001841]", "6": "K Homology domain, type 1 [IPR004088]", "7": "WW domain [IPR001202]", "8": "Bromodomain [IPR001487]", "9": "K Homology domain [IPR004087]", "10": "Immunoglobulin subtype 2 [IPR003598]", "11": "Immunoglobulin subtype [IPR003599]", "12": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "13": "SNF2, N-terminal [IPR000330]", "14": "SH3 domain [IPR001452]", "15": "Zinc finger, PHD-finger [IPR019787]", "16": "PWWP domain [IPR000313]", "17": "Zinc finger, CCCH-type [IPR000571]", "18": "Pleckstrin homology domain [IPR001849]", "19": "MPN domain [IPR037518]", "20": "Zinc finger C2H2-type [IPR013087]", "21": "FERM central domain [IPR019748]", "22": "Band 4.1 domain [IPR019749]", "23": "Rab-GTPase-TBC domain [IPR000195]", "24": "Zinc finger, PHD-type [IPR001965]", "25": "C2 domain [IPR000008]", "26": "Ubiquitin-like domain [IPR000626]", "27": "FERM domain [IPR000299]", "28": "FERM, C-terminal PH-like domain [IPR018980]", "29": "FERM, N-terminal [IPR018979]", "30": "Helicase, C-terminal [IPR001650]", "31": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "32": "Post-SET domain [IPR003616]", "33": "TOG domain [IPR034085]", "34": "Protein kinase domain [IPR000719]", "35": "Kinesin motor domain [IPR001752]", "36": "Phox homology [IPR001683]", "37": "DnaJ domain [IPR001623]", "38": "Target SNARE coiled-coil homology domain [IPR000727]", "39": "ATPase, AAA-type, core [IPR003959]", "40": "RNA-binding domain, S1 [IPR022967]", "41": "S1 domain [IPR003029]", "42": "Dynamin, N-terminal [IPR045063]", "43": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "44": "RNA recognition motif domain [IPR000504]"}
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