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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:5ab68d419c4cd9a2b0b4bc4c4b690a598d1c48bb0ecddec6e8b37672ed1d84e3
+size 77713

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3368,
+    "annotations_size": 54,
+    "title": "Average number of proteins per term",
+    "value": 2.8703703703703702
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C159/C159_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9815750371471024	2.1055391516568225	0.0352444030004295	0.8559429334248774	0.2737234184219387	3	Q9HB40,P10619	2
+Histidine acid phosphatase active site [IPR033379]	0.8585858585858602	0.9239745795320694	0.3554995510924559	0.9999999999501054	0.5484850216855034	2	Q9NPH0	1
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7673796791443882	0.6105206977240846	0.5415169368940571	1.0	0.7132174290799776	2	Q7LG56	1
+Peptidase S9, serine active site [IPR002471]	0.4114676173499828	0.0245643288236043	0.980402472183442	1.0	0.994682302332085	2	P48147	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.3043995243757384	0.006664795005974	0.994682302332085	1.0	0.994682302332085	4	P25705,P06576,P21281	3

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Carboxylesterase type B, active site [IPR019826]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADA", "ADSS", "AKT2", "AKT3", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CES3", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK3", "MAPK7", "MARK2", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "ATP5A1", "ATP5B", "ATP6V1B2", "CTSA", "PREP", "RRM2B", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:0230a85cc0ad0bd11bff24bb4f505c7dd12b30204fec84f9de7cc6a66f9ba640
+size 76471

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3368,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 5.129032258064516
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C159/C159_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9702734839476804	2.4497550111008044	0.0142953442513018	0.3600426323755511	0.2215778358951788	4	P07437,Q9BVA1,P04350	3
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.647653000594185	0.2767237845178605	0.7819922073802721	1.0	0.9081263688861736	2	O15270	1
+Peptidase M16, zinc-binding site [IPR001431]	0.4120460677837861	0.2631043656339212	0.7924701391711637	1.0	0.9081263688861736	5	Q10713	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.4914276200768045	0.2620846877941654	0.7932561516567733	1.0	0.9081263688861736	40	Q02818,Q9NWM8,Q14257,O43852,Q9BRK5,Q96AY3,Q9H223,O95302,Q6NUK1,P41208,P80303,O95202,Q9Y680	13

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT2", "AKT3", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQCB1", "IQGAP1", "IQGAP2", "IRAK1", "LETM1", "MACF1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK3", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "EHD4", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "LETM1", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SDF4", "SLC25A24", "SPTLC2", "TUBB", "TUBB2B", "TUBB4A"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "Oxysterol-binding protein, conserved site [IPR018494]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ee48efdedac0d484234bd27b04b58e4569d7a8039c17d70ac779cf35ec771ee6
+size 86672

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3368,
+    "annotations_size": 279,
+    "title": "Average number of proteins per term",
+    "value": 2.774193548387097
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C159/C159_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,25 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9702734839476806	2.4497550111008044	0.0142953442513018	0.9819963985655163	0.4543734575726672	4	P07437,Q9BVA1,P04350	3
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7500265482844729	1.8418408588741684	0.0654984315045397	0.9999999938080184	0.4907069299491198	6	Q13190,O60499,Q9P2W9,Q13277	4
+Intermediate filament protein, conserved site [IPR018039]	0.6563793452720307	1.602468676353843	0.1090520088345718	0.9999999999999898	0.4987788600794353	8	P07197,P08670,P07196,P48681	4
+Haem oxygenase conserved site [IPR018207]	0.9979203802733214	1.441447458237146	0.149458310915274	1.0	0.5519052928323555	2	P30519	1
+Tetraspanin, conserved site [IPR018503]	0.9928698752228164	1.4224066322711528	0.1549082388868901	1.0	0.55409485448003	2	O60637	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.7978478681309656	1.391450630011935	0.1640888206869544	1.0	0.5795035566032947	3	Q9Y2T2	1
+ABC transporter-like, conserved site [IPR017871]	0.618143660459536	1.3291573801921437	0.1837960527859357	1.0	0.5962685898520471	12	Q03518,P33527,Q03519,P08183,O75027	5
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5867164015073968	1.2464086421380272	0.2126144100990039	1.0	0.6039188242024021	8	P49721,P28072	2
+Guanylate kinase, conserved site [IPR020590]	0.6114657410658415	1.1959650708032896	0.2317101900430742	1.0	0.6041789067478291	6	Q9NZW5,Q12959	2
+Sugar transporter, conserved site [IPR005829]	0.9224598930481284	1.1582723919181248	0.2467528941734595	1.0	0.6315968575632589	2	P11166	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.8784907902554959	0.9961216826886709	0.3191910259184458	1.0	0.7175239007392108	2	P11279	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.6500634985992316	0.8136143399599041	0.4158659202799968	1.0	0.7999324419306933	3	P50570	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8122400475341667	0.760465120215914	0.44697661082302	1.0	0.7999324419306933	2	Q9BTY2	1
+Sterol reductase, conserved site [IPR018083]	0.8071895424836653	0.74311665659818	0.4574110560542321	1.0	0.7999324419306933	2	Q14739	1
+Sulfatase, conserved site [IPR024607]	0.7994652406417156	0.7167940863775591	0.4735011611469732	1.0	0.8089339316612423	2	P34059	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7688651218063015	0.6153207838640712	0.5383428944503783	1.0	0.8695468179988896	2	P04439	1
+DnaJ domain, conserved site [IPR018253]	0.4665180393471423	0.5769351016448129	0.5639832972102536	1.0	0.8700629438724875	11	Q9Y2G8,Q9NVH1,Q96KC8	3
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.4729663258710117	0.549898821456202	0.5823887726272332	1.0	0.8783052300702597	6	P42345,P42356,O00443	3
+Thioredoxin, conserved site [IPR017937]	0.4219942423119771	0.3517945932135188	0.7249923136928091	1.0	0.9276706474240998	12	O95881,Q9H3N1,Q9H1E5	3
+Mrp, conserved site [IPR000808]	0.5567439096850972	0.116519184001061	0.907241083018105	1.0	0.969809433571078	2	Q9Y5Y2	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.3367043426531791	0.0508444734578491	0.959449451990471	1.0	0.9951167178637228	6	P22059,Q9BZF1,Q9BXB4,Q9H4L5,Q96SU4	5
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.3148038049940462	0.0187359956656859	0.985051712900502	1.0	0.9974580949386436	4	Q16539,Q13164,P27361	3
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	0.9974580949386436	2	P30876	1
+Hexapeptide transferase, conserved site [IPR018357]	0.2798573975044668	0.0168944305472828	0.986520835913659	1.0	0.9974580949386436	2	Q9Y5P6	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "COQ6", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "ITGA2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MID1", "MIF", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR1B", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM2", "STMN1", "STRN", "STRN3", "STRN4", "STX10", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2B", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR37", "WDR41", "WDR47", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "AP3M1", "DLG1", "DNAJC1", "DNAJC11", "DNAJC16", "DNM2", "FUCA2", "GALNS", "GMPPB", "HLA-A", "HMOX2", "LAMP1", "LBR", "MAPK14", "MAPK3", "MAPK7", "MPP6", "MTOR", "NEFL", "NEFM", "NES", "NUBP2", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "PI4KA", "PIK3C2A", "POLR2B", "PSMB2", "PSMB6", "SLC2A1", "STX10", "STX18", "STX3", "STX5", "TAP1", "TAP2", "TMX1", "TMX4", "TSPAN3", "TUBB", "TUBB2B", "TUBB4A", "TXNDC12", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "ABC transporter type 1, transmembrane domain [IPR011527]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "ABC transporter type 1, transmembrane domain [IPR011527]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "4": "Dynamin, N-terminal [IPR045063]", "5": "Phospholipid/glycerol acyltransferase [IPR002123]", "6": "ABC transporter-like, ATP-binding domain [IPR003439]", "7": "Immunoglobulin-like domain [IPR007110]", "8": "EF-hand domain [IPR002048]", "9": "FERM, C-terminal PH-like domain [IPR018980]", "10": "FERM, N-terminal [IPR018979]", "11": "Thioredoxin domain [IPR013766]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:7003ab0db769d8ff61f3a8bcd16000ebe15436036f97818751bc1e4391cf2558
+size 155646

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	5	7	2.273661694401363	0.022986334977632	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.034345662156267	1.0	1.0	0.4134158684498193	0.0193421266882966
+ABC transporter type 1, transmembrane domain [IPR011527]	5	8	2.1727459634225847	0.0297994423237759	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	0.0011851500038933	1.0	0.1336663515258769	0.048794410492492	0.0047081007231922
+GOLD domain [IPR009038]	4	6	2.126238355476763	0.0334834179407061	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.3533059953492423	0.0583291306653072	0.1169218221283287	0.2702644522094949	0.0026623648375823
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	5	12	2.1135920184180743	0.0345501281517546	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	1.728510446875797e-06	1.0	0.1169218221283287	0.0001929986818147	1.5359091342738864e-05
+Major facilitator superfamily domain [IPR020846]	4	5	1.9681761857161453	0.049047769332605	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	0.0748224723025691	1.0	1.0	0.5169845217152549	0.0537154947848729

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3368,
+    "annotations_size": 2740,
+    "title": "Average number of proteins per term",
+    "value": 2.206934306569343
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C159/C159_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,249 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.9702734839476806	2.4497550111008044	0.0142953442513018	1.0	0.672035248670933	4	P07437,Q9BVA1,P04350	3
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.9702734839476806	2.4497550111008044	0.0142953442513018	1.0	0.672035248670933	4	P07437,Q9BVA1,P04350	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7896429464845466	2.273661694401363	0.022986334977632	1.0	0.672035248670933	7	Q9HD20,P35670,P16615,P05023,P20020	5
+ERAP1-like C-terminal domain [IPR024571]	0.92271105826397	2.2626087899959684	0.0236598157991094	1.0	0.672035248670933	4	Q6P179,Q9UIQ6,P55786	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7725884819223334	2.1727459634225847	0.0297994423237759	1.0	0.672035248670933	8	Q03518,P33527,Q03519,P08183,O75027	5
+GOLD domain [IPR009038]	0.8135783377243058	2.126238355476763	0.0334834179407061	1.0	0.672035248670933	6	P49755,Q15363,Q9BVK6,Q9Y3A6	4
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8885255648038018	2.1256911284618485	0.0335289861078447	1.0	0.672035248670933	4	Q96G23,Q15629,P27544	3
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7768911335084605	2.1135920184180743	0.0345501281517546	1.0	0.672035248670933	12	Q9NWM8,P62942,P26885,O95302,Q9Y680	5
+Reticulon [IPR003388]	0.9500742942050522	1.9856425804691984	0.0470730248896869	1.0	0.672035248670933	3	O95197,Q9NQC3	2
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9471025260029716	1.974266968033422	0.04835139477915	1.0	0.672035248670933	3	A6NIH7,Q13432	2
+Major facilitator superfamily domain [IPR020846]	0.8135593220338806	1.9681761857161453	0.049047769332605	1.0	0.672035248670933	5	Q9H2V7,P11166,Q7L0J3,Q14728	4
+LEM domain [IPR003887]	0.8011816694351428	1.91561007408972	0.0554147463131589	1.0	0.672035248670933	5	P50402,P42167,Q86XL3	3
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.763531719520545	1.9029916446363964	0.0570416354925273	1.0	0.672035248670933	6	Q9UIQ6,Q6P179,P55786	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.763531719520545	1.9029916446363964	0.0570416354925273	1.0	0.672035248670933	6	Q9UIQ6,Q6P179,P55786	3
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.7107813748159533	1.8736016224016416	0.0609853542666583	1.0	0.6752137466038084	8	Q8IWA4,Q9UQ16,Q9H223,O60313,P50570	5
+Dynamin, N-terminal [IPR045063]	0.7107813748159533	1.8736016224016416	0.0609853542666583	1.0	0.6752137466038084	8	Q8IWA4,Q9UQ16,Q9H223,O60313,P50570	5
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6997917286521708	1.8396193695302667	0.0658241386293252	1.0	0.6752137466038084	7	Q6UWP7,Q8NF37,Q99943,Q9HCL2,Q92604,Q9NUQ2	6
+Glycosyltransferase 2-like [IPR001173]	0.7826767942300155	1.836508342051655	0.0662825094768038	1.0	0.6752137466038084	5	Q10472	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.9068956780510316	1.8193273152859033	0.0688615084506871	1.0	0.6752137466038084	3	Q10472	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7966706302021361	1.7482652159894725	0.0804181134502532	1.0	0.6850567567221272	4	P16615,P05023,P20020	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7966706302021361	1.7482652159894725	0.0804181134502532	1.0	0.6850567567221272	4	P16615,P05023,P20020	3
+MHC class I-like antigen recognition-like [IPR011161]	0.7523044900386519	1.7053966599493409	0.088120470860241	1.0	0.6862773715472065	5	P10321,P04439,P01889,Q9UNN8	4
+FAD dependent oxidoreductase [IPR006076]	0.7706356700072224	1.638996816746231	0.1012139226504587	1.0	0.6965740550005879	4	Q96CU9	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.6556943143556575	1.6191764049524089	0.105409313188348	1.0	0.6965740550005879	7	O00264,O43169,O15173	3
+PA domain [IPR003137]	0.8520059435364047	1.6050596191351532	0.1084806848410488	1.0	0.6965740550005879	3	O43567,Q8TCT8	2
+Intermediate filament, rod domain [IPR039008]	0.6563793452720307	1.602468676353843	0.1090520088345718	1.0	0.6965740550005879	8	P07197,P08670,P07196,P48681	4
+Guanylate kinase-like domain [IPR008144]	0.6560801965782327	1.600959018759997	0.1093859962508125	1.0	0.6965740550005879	8	Q07157,Q9UDY2,Q9NZW5,Q12959	4
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.6560801965782327	1.600959018759997	0.1093859962508125	1.0	0.6965740550005879	8	Q07157,Q9UDY2,Q9NZW5,Q12959	4
+Intermediate filament head, DNA-binding domain [IPR006821]	0.750325369219299	1.5531651434079123	0.1203836863417642	1.0	0.7067365250588282	4	P07197,P07196	2
+Ricin B, lectin domain [IPR000772]	0.7500006883439732	1.5517892376218752	0.1207126619443546	1.0	0.7067365250588282	4	Q10472	1
+Zinc finger, CHHC-type [IPR012996]	0.8347696879643394	1.5372525872480989	0.1242314671241713	1.0	0.7134059894348261	3	P55795,P31943	2
+Mu homology domain [IPR028565]	0.7359560352127393	1.492168023241234	0.1356551029024377	1.0	0.7237692366286497	4	Q9Y2T2	1
+Tim10-like [IPR004217]	0.7339476813317415	1.4836265900968542	0.1379080111787711	1.0	0.7237692366286497	4	Q9Y5J9,Q9Y5J7,Q9Y5J6	3
+Acyltransferase, C-terminal domain [IPR032098]	0.8092124814264493	1.4363885542894408	0.1508918082158012	1.0	0.7489919465784339	3	Q92604,Q9NUQ2	2
+Dynamin, GTPase domain [IPR001401]	0.7184153977902037	1.417451041527931	0.1563510986900405	1.0	0.7518357928335633	4	P50570,O60313	2
+Potentiating neddylation domain [IPR005176]	0.9890077243018424	1.4078496845151072	0.1591755846623908	1.0	0.7518357928335633	2	Q9BTE7	1
+Glycosyl transferase, family 1 [IPR001296]	0.7955423476968801	1.382329962614879	0.1668704100622506	1.0	0.7620415392842781	3	Q9BT22,P37287	2
+Prenylcysteine lyase [IPR010795]	0.975935828877006	1.3586130444943805	0.1742692394429528	1.0	0.7784106410477363	2	Q9UHG3	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9691027926322048	1.3329025343686978	0.1825637907802022	1.0	0.7858880479953716	2	Q8N2A8	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.618143660459536	1.3291573801921437	0.1837960527859357	1.0	0.7868768509897872	12	Q03518,P33527,Q03519,P08183,O75027	5
+Peptidase M48 [IPR001915]	0.9667260843731438	1.323965096829594	0.1855146367855591	1.0	0.7891025845142771	2	O75844	1
+CBS domain [IPR000644]	0.596523826905383	1.3168880608047602	0.1878761490490754	1.0	0.7926983616901633	7	P51798,P51790,Q8NE01	3
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.7786032689450232	1.315296447941818	0.1884102914511207	1.0	0.7926983616901633	3	Q13505,O75431	2
+Metaxin, glutathione S-transferase domain [IPR033468]	0.7786032689450232	1.315296447941818	0.1884102914511207	1.0	0.7926983616901633	3	Q13505,O75431	2
+Longin domain [IPR010908]	0.776523031203567	1.3070634557537704	0.1911911612746391	1.0	0.7926983616901633	3	P51809,O15498	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.776523031203567	1.3070634557537704	0.1911911612746391	1.0	0.7926983616901633	3	P51809,O15498	2
+Immunoglobulin C1-set [IPR003597]	0.7690936106983662	1.2776629485973707	0.2013682947227835	1.0	0.8105618672634426	3	P10321,P04439	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7690936106983662	1.2776629485973707	0.2013682947227835	1.0	0.8105618672634426	3	P10321,P04439	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7690936106983662	1.2776629485973707	0.2013682947227835	1.0	0.8105618672634426	3	P10321,P04439	2
+BRICHOS domain [IPR007084]	0.9423648247177664	1.232565714372978	0.2177378351391812	1.0	0.8159092539589886	2	Q9Y287	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5826538147738364	1.2057720694230536	0.2279053877382955	1.0	0.8192311524958249	9	Q6PK18,Q8N543,Q32P28,P13674	4
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5826538147738364	1.2057720694230536	0.2279053877382955	1.0	0.8192311524958249	9	Q6PK18,Q8N543,Q32P28,P13674	4
+L27 domain [IPR004172]	0.6283438938417004	1.1577200903212876	0.2469782826042026	1.0	0.8396035909869916	5	Q9NZW5,Q12959	2
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.7375995874227899	1.153220101297149	0.2488200549080419	1.0	0.8398681356124696	3	O14874	1
+Histidine kinase domain [IPR005467]	0.7375995874227899	1.153220101297149	0.2488200549080419	1.0	0.8398681356124696	3	O14874	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.6552498323481637	1.1471161807206116	0.2513336073159409	1.0	0.8418754083687996	4	Q4J6C6	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.622640553382152	1.1322751285002912	0.2575187831678345	1.0	0.8460449231173459	5	Q6PK18,Q32P28,P13674	3
+Fatty acid hydroxylase [IPR006694]	0.9049316696375548	1.0932516055159196	0.2742833446501906	1.0	0.8718519307906292	2	Q15800	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.9013666072489632	1.080082694750775	0.2801053572707608	1.0	0.8775214600895628	2	P23786	1
+Post-SET domain [IPR003616]	0.6083845018262595	1.0687074051588916	0.2852015337104232	1.0	0.8822195334652422	5	Q03164,O15047	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.7078751857355137	1.0364412472668585	0.2999963357974309	1.0	0.8956404215644254	3	P61289,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.7078751857355137	1.0364412472668585	0.2999963357974309	1.0	0.8956404215644254	3	P61289,Q9UL46	2
+SUN domain [IPR012919]	0.6959061429740291	0.9897367394762534	0.3223028124535543	1.0	0.9252262045906676	3	O94901	1
+L27 domain, C-terminal [IPR014775]	0.6174197384066504	0.9856631943919764	0.324298416264182	1.0	0.9252262045906676	4	Q14168,O14936,Q9NZW5	3
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8740344622697609	0.9798882818230354	0.3271412678868763	1.0	0.9252262045906676	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8740344622697609	0.9798882818230354	0.3271412678868763	1.0	0.9252262045906676	2	Q9Y282	1
+Fatty acid desaturase domain [IPR005804]	0.8728461081402306	0.9755668759201096	0.3292791459838116	1.0	0.9252262045906676	2	O15121	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8686868686868705	0.9604677200651216	0.3368198695673596	1.0	0.927099392608554	2	O15254	1
+Syntaxin, N-terminal domain [IPR006011]	0.6855869242199117	0.9496683249645343	0.342280809260973	1.0	0.9279404982601612	3	O15400,Q13277	2
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.682710112735754	0.9385352527008552	0.3479694091573293	1.0	0.929930171546657	3	P51784	1
+Peptidase M28 [IPR007484]	0.6826151560178316	0.9381680721798348	0.3481580434791058	1.0	0.929930171546657	3	P02786,Q7Z2K6	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.5281232350823575	0.9241104136697949	0.3554288319745373	1.0	0.9380278923054284	9	Q13190,O60499,O95721,Q13277	4
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8541295306001189	0.9079593017544092	0.3638997243893822	1.0	0.9380278923054284	2	Q9NVI7	1
+CNNM, transmembrane domain [IPR002550]	0.8529411764705896	0.9036977835479768	0.3661556747282604	1.0	0.9380278923054284	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.8529411764705896	0.9036977835479768	0.3661556747282604	1.0	0.9380278923054284	2	Q8NE01	1
+Band 3 cytoplasmic domain [IPR013769]	0.852049910873443	0.9005042484887894	0.3678519654162935	1.0	0.9384677702426856	2	Q9Y6M7	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.852049910873443	0.9005042484887894	0.3678519654162935	1.0	0.9384677702426856	2	Q9Y6M7	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.6689065673274104	0.8853742459525429	0.3759548179159087	1.0	0.943209104479917	3	P42356	1
+SET domain [IPR001214]	0.5126151211270462	0.8818473026037127	0.3778593876515264	1.0	0.943209104479917	7	Q03164,O15047,O96028	3
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.5925244719331018	0.8804486417697311	0.3786163157489599	1.0	0.943209104479917	4	Q9Y4E8,P51784	2
+Immunoglobulin V-set domain [IPR013106]	0.5893351023090152	0.8670623446302047	0.3859078510854905	1.0	0.9432538019395575	4	P78310	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.6589978035663969	0.8475101353962722	0.3967108401481112	1.0	0.9502912736865572	3	Q9NUQ9	1
+LEM-like domain [IPR013146]	0.8348187759952506	0.839229620680019	0.4013404684159216	1.0	0.951803731048608	2	P42167	1
+CARG-binding factor, N-terminal [IPR012956]	0.8339275103980994	0.8360858868807056	0.4031065873911843	1.0	0.951803731048608	2	Q99729	1
+Extended PHD (ePHD) domain [IPR034732]	0.5810423023633324	0.8323777861180093	0.4051957366217364	1.0	0.951803731048608	4	Q9UGU0,Q03164	2
+SUN coiled coil domain 2 [IPR040994]	0.830065359477125	0.8224941980377791	0.4107956874395064	1.0	0.951803731048608	2	O94901	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8279857397504466	0.8151970013683979	0.4149595540436768	1.0	0.9519403688948964	2	O43390	1
+Dynamin stalk domain [IPR000375]	0.6500634985992316	0.8136143399599041	0.4158659202799968	1.0	0.9519403688948964	3	P50570	1
+Dynamin GTPase effector [IPR003130]	0.6500634985992316	0.8136143399599041	0.4158659202799968	1.0	0.9519403688948964	3	P50570	1
+GTPase effector domain [IPR020850]	0.6500634985992316	0.8136143399599041	0.4158659202799968	1.0	0.9519403688948964	3	P50570	1
+START domain [IPR002913]	0.8270944741533033	0.8120743119416622	0.4167489921176299	1.0	0.9527490638112436	2	Q9NQZ5	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6448736998514126	0.7940421549751387	0.4271708908043612	1.0	0.956832271966946	3	Q9ULX6,O43823	2
+FAD linked oxidase, N-terminal [IPR006094]	0.8196672608437374	0.786164501351744	0.4317711200451857	1.0	0.956832271966946	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8196672608437374	0.786164501351744	0.4317711200451857	1.0	0.956832271966946	2	Q15392	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8122400475341667	0.760465120215914	0.44697661082302	1.0	0.9607685471317452	2	Q9BTY2	1
+Marvel domain [IPR008253]	0.8113487819370231	0.7573959761731667	0.4488126661049461	1.0	0.9622431182531708	2	O43760	1
+Elp3/MiaB/NifB [IPR006638]	0.6315007429420517	0.744050966015023	0.4568456422535547	1.0	0.9628044946028206	3	Q5VV42,Q9H9T3	2
+Radical SAM [IPR007197]	0.6315007429420517	0.744050966015023	0.4568456422535547	1.0	0.9628044946028206	3	Q5VV42,Q9H9T3	2
+Immunoglobulin-like domain [IPR007110]	0.5058536077262208	0.7373721046340967	0.4608960944982816	1.0	0.963848959092904	13	P10321,P35613,Q9BY67,P01889,P78310,Q08722,P04439	7
+Sulfatase, N-terminal [IPR000917]	0.7994652406417156	0.7167940863775591	0.4735011611469732	1.0	0.9688972198763592	2	P34059	1
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.4831955439173159	0.7126190656086158	0.4760815107119722	1.0	0.969327708574676	8	P42345,P42356,O00443,Q13315	4
+Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]	0.7976827094474174	0.7107572109870441	0.4772347003165103	1.0	0.969327708574676	2	P51572	1
+BAP29/BAP31, transmembrane domain [IPR040463]	0.7976827094474174	0.7107572109870441	0.4772347003165103	1.0	0.969327708574676	2	P51572	1
+Agenet-like domain [IPR008395]	0.6117687003814257	0.6716263872692174	0.5018215752726749	1.0	0.9862120740204652	3	Q06787	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.6117687003814257	0.6716263872692174	0.5018215752726749	1.0	0.9862120740204652	3	Q06787	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.6117687003814257	0.6716263872692174	0.5018215752726749	1.0	0.9862120740204652	3	Q06787	1
+Fxr1, tudor domain [IPR041560]	0.6117687003814257	0.6716263872692174	0.5018215752726749	1.0	0.9862120740204652	3	Q06787	1
+Band 7 domain [IPR001107]	0.4703680373392401	0.6657428233343138	0.5055754966300794	1.0	0.9862120740204652	7	Q99623,O75477,O75955	3
+Exportin-2, central domain [IPR013713]	0.6101040118870741	0.6655984665060521	0.5056677868477308	1.0	0.9862120740204652	3	O15397,O95373	2
+SLC12A transporter, C-terminal [IPR018491]	0.7813428401663733	0.6561214838575311	0.5117459623293454	1.0	0.9875372925611487	2	Q9Y666	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.7813428401663733	0.6561214838575311	0.5117459623293454	1.0	0.9875372925611487	2	Q9Y666	1
+ELMO domain [IPR006816]	0.7774806892453981	0.6434032045875847	0.519962504600644	1.0	0.9899920507756402	2	Q96JJ3	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7733214497920409	0.6297953662287595	0.5288284777705323	1.0	0.9899920507756402	2	P13674	1
+Rhodanese-like domain [IPR001763]	0.4902028318541711	0.627069404375424	0.5306137415288883	1.0	0.9906000960176532	6	Q9NUY8,Q8NCN5	2
+RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]	0.7724301841948931	0.6268916357435069	0.5307302704211367	1.0	0.9906000960176532	2	Q96DH6	1
+RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]	0.7724301841948931	0.6268916357435069	0.5307302704211367	1.0	0.9906000960176532	2	Q96DH6	1
+tRNA synthetases class I, catalytic domain [IPR032678]	0.7632204396910311	0.5971479161758068	0.5504086291932193	1.0	0.9961160132030522	2	P49589	1
+Ubiquitin-like domain, USP-type [IPR028135]	0.7471776589423688	0.5465453703037499	0.5846911094032072	1.0	1.0	2	P51784	1
+Tim44-like domain [IPR007379]	0.7433155080213947	0.5346078174618466	0.5929210767755233	1.0	1.0	2	O43615	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4521827808427106	0.5240420106556541	0.6002493204614625	1.0	1.0	10	O15254,Q709F0,Q15067	3
+Fzo/mitofusin HR2 domain [IPR006884]	0.7397504456328028	0.5236770201416957	0.6005032014508456	1.0	1.0	2	Q8IWA4	1
+NOPS [IPR012975]	0.5682799982391886	0.5192866950450821	0.60356083013884	1.0	1.0	3	P23246	1
+Peptidase M16, N-terminal [IPR011765]	0.4381063156284694	0.5060328491365532	0.6128335894748851	1.0	1.0	7	Q10713,Q5JRX3	2
+Peptidase M16, C-terminal [IPR007863]	0.4381063156284694	0.5060328491365532	0.6128335894748851	1.0	1.0	7	Q10713,Q5JRX3	2
+Ulp1 protease family, C-terminal catalytic domain [IPR003653]	0.7245989304812882	0.4782131045564952	0.6324985363246509	1.0	1.0	2	Q96LD8	1
+Citron homology (CNH) domain [IPR001180]	0.7192513368984006	0.4625688005990477	0.6436734762909024	1.0	1.0	2	Q8WUH2	1
+Immunoglobulin subtype [IPR003599]	0.4331548506156018	0.449537132984823	0.6530442274029813	1.0	1.0	9	P35613,P78310	2
+Immunoglobulin subtype 2 [IPR003598]	0.4331548506156018	0.449537132984823	0.6530442274029813	1.0	1.0	9	P35613,P78310	2
+Major sperm protein (MSP) domain [IPR000535]	0.5390787518573567	0.4243403463415708	0.6713176189099306	1.0	1.0	3	Q9P0L0,O95292	2
+PUA domain [IPR002478]	0.4613555291319723	0.3692299270272517	0.7119563508760278	1.0	1.0	4	Q9ULC4,P41214,Q9Y221	3
+KHDRBS, Qua1 domain [IPR032571]	0.6850861556743972	0.3680761875009621	0.7128164260258281	1.0	1.0	2	O75525	1
+Sam68, tyrosine-rich domain [IPR032335]	0.6850861556743972	0.3680761875009621	0.7128164260258281	1.0	1.0	2	O75525	1
+RBM1CTR [IPR012604]	0.6830065359477189	0.3626502957071717	0.7168661337317526	1.0	1.0	2	P38159	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.516493313521547	0.3560136210454025	0.7218303645020037	1.0	1.0	3	Q1KMD3,Q9BUJ2	2
+Class I myosin, motor domain [IPR036072]	0.5156017830609229	0.3534187083937465	0.7237745623589777	1.0	1.0	3	O00159,O94832	2
+Class I myosin tail homology domain [IPR010926]	0.5156017830609229	0.3534187083937465	0.7237745623589777	1.0	1.0	3	O00159,O94832	2
+Peptidase M14, carboxypeptidase A [IPR000834]	0.6720142602495613	0.3346355915811506	0.7378999931004708	1.0	1.0	2	O75976	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.6625074272133169	0.3113350778821248	0.755545903131309	1.0	1.0	2	Q9UEY8	1
+FERM adjacent (FA) [IPR014847]	0.4427932639441703	0.3078262409259368	0.7582145531197639	1.0	1.0	4	Q9Y4F1,Q9Y2J2	2
+CRIB domain [IPR000095]	0.4989598811292736	0.3065170134978134	0.7592110279399618	1.0	1.0	3	Q13153,Q9Y5S2	2
+Lamin tail domain [IPR001322]	0.4945022288261531	0.2944684625123048	0.7683999589134756	1.0	1.0	3	P20700,Q03252	2
+EF-hand domain [IPR002048]	0.5220139453548475	0.2841067370493852	0.7763285841949348	1.0	1.0	48	Q02818,Q9NWM8,Q14257,O43852,Q9BRK5,Q96AY3,Q9H223,O95302,Q6NUK1,Q96C19,P41208,O75071,O43149,P80303,O95202,Q8IYU8,Q9Y680	17
+Ribosomal protein L10e/L16 [IPR016180]	0.6434937611408278	0.2674365773463963	0.789133040031436	1.0	1.0	2	P27635	1
+Armadillo repeat-containing domain [IPR006911]	0.6423054070112972	0.2648161498136813	0.7911510951715512	1.0	1.0	2	Q96D09	1
+SAC3/GANP/THP3, conserved domain [IPR005062]	0.6327985739750528	0.2443880092577438	0.8069303275114321	1.0	1.0	2	O60318	1
+EF-hand, Ca insensitive [IPR014837]	0.4701337295690952	0.232720449937026	0.8159784884048524	1.0	1.0	3	Q13813,P12814	2
+Chromo domain subgroup [IPR017984]	0.4695393759286792	0.2313047979305891	0.8170780195380802	1.0	1.0	3	Q13185,P83916	2
+Chromo shadow domain [IPR008251]	0.4695393759286792	0.2313047979305891	0.8170780195380802	1.0	1.0	3	Q13185,P83916	2
+PSI domain [IPR016201]	0.6209150326797471	0.220212229006854	0.825705873017369	1.0	1.0	2	O15031	1
+NUC153 [IPR012580]	0.61556743909686	0.2098336570531597	0.8337975032699105	1.0	1.0	2	Q9H501	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.4564635958395261	0.2012967420575842	0.8404665498902018	1.0	1.0	3	P52888,Q9BYT8	2
+JmjC domain [IPR003347]	0.404577883472043	0.1951048879079976	0.8453108361150459	1.0	1.0	4	Q6NYC1,Q7LBC6,Q9UPP1	3
+FERM, C-terminal PH-like domain [IPR018980]	0.3650699196667712	0.1815596427622549	0.8559283227740848	1.0	1.0	7	Q9Y2J2,P26038,O43491,P11171,Q9Y4F1,P15311	6
+FERM, N-terminal [IPR018979]	0.3650699196667712	0.1815596427622549	0.8559283227740848	1.0	1.0	7	Q9Y2J2,P26038,O43491,P11171,Q9Y4F1,P15311	6
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.5989304812834321	0.1795590120334446	0.8574987852488758	1.0	1.0	2	Q99584	1
+Tudor domain [IPR002999]	0.365349256869242	0.1699937850887656	0.8650150242950483	1.0	1.0	8	Q14739	1
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.4413075780089172	0.1693030000242086	0.8655583163691607	1.0	1.0	3	P82663,Q8N983	2
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.3779276713843481	0.1581036717761478	0.8743751073455264	1.0	1.0	5	Q9UKU0	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.35885115826195	0.1575421126100545	0.8748176211860654	1.0	1.0	7	P78417,Q9H7Z7	2
+HECT domain [IPR000569]	0.3745886835633194	0.1558725896418564	0.8761334514883532	1.0	1.0	12	P46934	1
+BRO1 domain [IPR004328]	0.5819964349376214	0.1518972094338953	0.879268009304464	1.0	1.0	2	Q5VW32	1
+Zinc finger, RanBP2-type [IPR001876]	0.3636948951330315	0.1513577278740197	0.8796935334935314	1.0	1.0	9	P35637,Q92804	2
+Helicase/SANT-associated domain [IPR014012]	0.5802139037433257	0.1491705237338558	0.8814190783831917	1.0	1.0	2	Q6ZRS2	1
+IPT domain [IPR002909]	0.4288261515601804	0.1452624769855999	0.8845036394643799	1.0	1.0	3	O15031,Q96KP1	2
+Gelsolin-like domain [IPR007123]	0.3693131132917132	0.1344703810295413	0.8930306308601415	1.0	1.0	5	O95486,O95487,P53992,Q13045	4
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.5701128936423161	0.134381193755144	0.8931011519538476	1.0	1.0	2	P51116	1
+OCRE domain [IPR041591]	0.4205052005943555	0.1304087202862891	0.8962430677176629	1.0	1.0	3	P78332,P52756	2
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.3552918245430259	0.1204683182867216	0.9041121751841076	1.0	1.0	9	O14874	1
+YTH domain [IPR007275]	0.556149732620332	0.1157699959713332	0.9078348303338152	1.0	1.0	2	Q9BYJ9	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.3715814506539733	0.1150433427700926	0.9084107675254904	1.0	1.0	4	P42694,O60306,Q9HCE1	3
+DNA mismatch repair protein MutS, core [IPR007696]	0.4092124814264508	0.111755869678841	0.9110169791441114	1.0	1.0	3	P20585,P43246	2
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.4092124814264508	0.111755869678841	0.9110169791441114	1.0	1.0	3	P20585,P43246	2
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.4092124814264508	0.111755869678841	0.9110169791441114	1.0	1.0	3	P20585,P43246	2
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.4092124814264508	0.111755869678841	0.9110169791441114	1.0	1.0	3	P20585,P43246	2
+Zinc finger, UBP-type [IPR001607]	0.3598921892040827	0.1100614601219738	0.9123606327824804	1.0	1.0	5	Q7Z569,Q9UPT9	2
+Sec23/Sec24 beta-sandwich [IPR012990]	0.3692033293697926	0.1099458570837077	0.9124523142704456	1.0	1.0	4	O95486,O95487,P53992	3
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.3692033293697926	0.1099458570837077	0.9124523142704456	1.0	1.0	4	O95486,O95487,P53992	3
+Sec23/Sec24, helical domain [IPR006900]	0.3692033293697926	0.1099458570837077	0.9124523142704456	1.0	1.0	4	O95486,O95487,P53992	3
+Sec23/Sec24, trunk domain [IPR006896]	0.3692033293697926	0.1099458570837077	0.9124523142704456	1.0	1.0	4	O95486,O95487,P53992	3
+MIRO domain [IPR020860]	0.5508021390374447	0.1091961222176127	0.9130469359409912	1.0	1.0	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.5508021390374447	0.1091961222176127	0.9130469359409912	1.0	1.0	2	Q8IXI2	1
+EF hand associated, type-2 [IPR013567]	0.5508021390374447	0.1091961222176127	0.9130469359409912	1.0	1.0	2	Q8IXI2	1
+Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]	0.3592030924769652	0.1083362642300503	0.9137289571934968	1.0	1.0	5	Q9NVN8,Q13823,Q8NC60,P36915	4
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.368014268727692	0.107431903073777	0.914446345966694	1.0	1.0	4	Q9UKA9,Q8WVV9,P26599	3
+FAD/NAD(P)-binding domain [IPR023753]	0.3542076641072749	0.0960790268096993	0.9234578084161564	1.0	1.0	5	Q9Y6N5	1
+Sec24-like, trunk domain [IPR041742]	0.3973254086181299	0.0939840817624345	0.9251218016739646	1.0	1.0	3	O95486,O95487	2
+Cyclic nucleotide-binding domain [IPR000595]	0.3521398212358554	0.0929432581505327	0.92594863942589	1.0	1.0	6	Q8IY17	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.5332739156268688	0.0897348035507136	0.9284979582632144	1.0	1.0	2	P49840	1
+Gamma-glutamyl cyclotransferase-like [IPR013024]	0.5326797385621036	0.0891297946756409	0.9289787588922972	1.0	1.0	2	O75223	1
+VHS domain [IPR002014]	0.3573127229488624	0.0858555164575813	0.9315812736056766	1.0	1.0	4	O75886,O60784,O14964	3
+SAB domain [IPR007477]	0.3893016344725131	0.0830536355231534	0.9338088919079184	1.0	1.0	3	P11171,Q9Y2J2	2
+Band 4.1, C-terminal [IPR008379]	0.3893016344725131	0.0830536355231534	0.9338088919079184	1.0	1.0	3	P11171,Q9Y2J2	2
+EB1, C-terminal [IPR004953]	0.522578728461094	0.0793749299755057	0.936734408694608	1.0	1.0	2	Q15691	1
+GUCT [IPR012562]	0.5181224004753494	0.075383080520614	0.9399099206914424	1.0	1.0	2	Q9BQ39	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.5062388591800483	0.065633743831321	0.9476694233316636	1.0	1.0	2	P42695	1
+Heat shock chaperonin-binding [IPR006636]	0.3404985590222054	0.064725463431467	0.94839258844174	1.0	1.0	5	P54725	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.3401724650609635	0.0640209365059493	0.948953556082363	1.0	1.0	5	Q9UBS4,P25685,Q96EY1,O60884	4
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.3714710252600315	0.0617504779766725	0.9507615410249086	1.0	1.0	3	P42694,O60306	2
+Guanine nucleotide exchange factor, N-terminal [IPR032691]	0.5005941770647728	0.0614419570507358	0.951007238565256	1.0	1.0	2	Q92538	1
+p21 activated kinase binding domain [IPR033923]	0.4988116458704808	0.0601748763495981	0.9520163552139502	1.0	1.0	2	Q13153	1
+Zinc finger, GATA-type [IPR000679]	0.3424494649227068	0.0590342730688072	0.9529248097427848	1.0	1.0	4	Q13330,Q8WUU5,Q86YP4	3
+CTP synthase GATase domain [IPR033828]	0.4800950683303765	0.0484235855342743	0.9613786628124412	1.0	1.0	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.4800950683303765	0.0484235855342743	0.9613786628124412	1.0	1.0	2	Q9NRF8	1
+Synaptotagmin, SMP domain [IPR039010]	0.4744503862151065	0.0454032542695937	0.9637858871323552	1.0	1.0	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.4744503862151065	0.0454032542695937	0.9637858871323552	1.0	1.0	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.4744503862151065	0.0454032542695937	0.9637858871323552	1.0	1.0	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.4744503862151065	0.0454032542695937	0.9637858871323552	1.0	1.0	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.4744503862151065	0.0454032542695937	0.9637858871323552	1.0	1.0	2	A0FGR8	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.3483284909845953	0.0439306168201016	0.9649597101589704	1.0	1.0	14	Q9UHX1	1
+Pre-PUA domain [IPR041366]	0.469696969696984	0.0430345123792009	0.965674022427017	1.0	1.0	2	Q9ULC4	1
+C2 DOCK-type domain [IPR027007]	0.4664289958407684	0.0414952130575526	0.9669011089957932	1.0	1.0	2	Q14185	1
+DOCKER domain [IPR027357]	0.4664289958407684	0.0414952130575526	0.9669011089957932	1.0	1.0	2	Q14185	1
+Thioredoxin domain [IPR013766]	0.3883292079559163	0.0413177257412951	0.9670426020383762	1.0	1.0	27	Q9H3N1,Q9BS26,P07237,Q9Y320,O95881,O43819,Q9Y2G8,P30048,Q6ZRP7,Q9H1E5	10
+PIK-related kinase [IPR014009]	0.329998790211601	0.0393662095250835	0.9685984199086788	1.0	1.0	4	P42345	1
+FATC domain [IPR003152]	0.329998790211601	0.0393662095250835	0.9685984199086788	1.0	1.0	4	P42345	1
+PIK-related kinase, FAT [IPR003151]	0.329998790211601	0.0393662095250835	0.9685984199086788	1.0	1.0	4	P42345	1
+Uncharacterised domain CHP00451 [IPR004521]	0.4610814022578876	0.0391272017458616	0.9687889737132676	1.0	1.0	2	Q9ULC4	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.3399702823179813	0.0334789436960251	0.9732926569143984	1.0	1.0	3	Q96EY1,O60884	2
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.4405822935234764	0.0316351654788988	0.974762999419252	1.0	1.0	2	Q8WUM0	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.4236482471776676	0.027083791591033	0.9783929024558742	1.0	1.0	2	Q92945	1
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.4230540701129052	0.0269473172610925	0.9785017534874184	1.0	1.0	2	O15027	1
+PITH domain [IPR010400]	0.4191919191919258	0.0260953160117767	0.9791813130730636	1.0	1.0	2	O43396	1
+STAG [IPR013721]	0.4183006535947808	0.0259071384643578	0.9793314062877454	1.0	1.0	2	Q8N3U4	1
+Stromalin conservative domain [IPR020839]	0.4183006535947808	0.0259071384643578	0.9793314062877454	1.0	1.0	2	Q8N3U4	1
+BSD domain [IPR005607]	0.4180035650623982	0.0258451003720765	0.9793808889548344	1.0	1.0	2	P32780	1
+Peptidase M20, dimerisation domain [IPR011650]	0.4168152109328685	0.0256003508168442	0.9795761062514434	1.0	1.0	2	Q8IYS1	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.3280832095096603	0.0255904130649814	0.9795840328333532	1.0	1.0	3	O15344,Q13049	2
+GRAM domain [IPR004182]	0.4141414141414306	0.0250692052022788	0.9799997631477492	1.0	1.0	2	Q969T9	1
+Ribosomal Proteins L2, RNA binding domain [IPR022666]	0.407902554961384	0.0239303794421467	0.9809081419266577	1.0	1.0	2	Q5T653	1
+Ribosomal protein L2, C-terminal [IPR022669]	0.407902554961384	0.0239303794421467	0.9809081419266577	1.0	1.0	2	Q5T653	1
+Bms1/Tsr1-type G domain [IPR030387]	0.4061200237670909	0.0236295897740905	0.9811480695103084	1.0	1.0	2	Q14692	1
+AARP2CN [IPR012948]	0.4061200237670909	0.0236295897740905	0.9811480695103084	1.0	1.0	2	Q14692	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.4061200237670909	0.0236295897740905	0.9811480695103084	1.0	1.0	2	Q14692	1
+LRRC8, pannexin-like TM region [IPR021040]	0.3829471182412473	0.0205742481410809	0.9835852831236918	1.0	1.0	2	Q8TDW0	1
+RQC domain [IPR018982]	0.3639334521687581	0.0190078273596149	0.9848348612086464	1.0	1.0	2	Q14191	1
+ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]	0.3639334521687581	0.0190078273596149	0.9848348612086464	1.0	1.0	2	Q14191	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	1.0	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	1.0	2	P30876	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	1.0	2	P30876	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	1.0	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.3582887700534839	0.0186651095321875	0.9851082619632135	1.0	1.0	2	P30876	1
+Clp ATPase, C-terminal [IPR019489]	0.3535353535353613	0.0184122869262847	0.9853099505550666	1.0	1.0	2	Q9H078	1
+Pleckstrin homology domain 8 [IPR041680]	0.336304218657171	0.0177229764274305	0.9858598509869314	1.0	1.0	2	Q9H4L5	1
+WH1/EVH1 domain [IPR000697]	0.3104575163398788	0.0171609728388483	0.9863081967638584	1.0	1.0	2	Q86YM7	1
+Sec63 domain [IPR004179]	0.2897473997028254	0.00850085689424	0.9932173792211164	1.0	1.0	3	O75643,Q9UGP8	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.3043995243757384	0.006664795005974	0.994682302332085	1.0	1.0	4	P25705,P06576,P21281	3
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.3043995243757384	0.006664795005974	0.994682302332085	1.0	1.0	4	P25705,P06576,P21281	3
+Nucleotidyl transferase domain [IPR005835]	0.2799405646359606	0.0057823578450399	0.9953863716603728	1.0	1.0	3	Q9Y5P6,Q9NR50	2