msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Protein localization	0.6028307422360595	5.2274849826721725	1.7183135003573216e-07	0.0002422528763997	7.237330752455577e-05	77	Q99595,Q9NS69,O60830,Q9BY49,Q9Y512,P51648,Q8N4H5,P50402,Q9UJS0,Q15388,Q2T9J0,Q9Y5J9,P12236,P39210,P05067,P21796,O14925,O43681,P46379,Q9Y5Y5,O00116,Q8TB36,P06576,O75431,O15254,P40855,Q10713,P09601,O43615,Q3ZCQ8,O43808,P28288,Q13011,Q9NR77,Q13505,O96008,Q13190,Q9Y3D6,O75381,Q9Y5J7,Q9NX63,Q9Y5J6,P12235,Q15067	44
Transport of small molecules	0.4972147314992758	5.194460509796507	2.0531434758639225e-07	0.0002894513606863	7.237330752455577e-05	164	Q8N4V1,Q70HW3,P61289,Q9C0H2,P45880,P30519,P21796,Q9Y487,Q8TDW0,P33527,Q9UBX3,Q9UPY5,Q93050,O00231,Q9HD20,P09601,P49721,P28288,P35610,P20618,Q15904,P53985,Q9BUN8,Q99576,Q8TB61,Q8WTV0,P63218,Q6PIU2,Q9Y277,P30825,P55011,P02786,P51798,P28070,P28072,Q9Y289,P21281,P20020,O75477,Q8TAD4,Q99808,Q9Y6M7,P11166,Q96PU5,P51790,Q9NW15,Q9BPX6,P16615,Q13616,P49720,Q9HD23,P08183,P05023,P35670,P35611,P12236,Q15043,Q15758,P56589,P07237,P61916,Q10713,O95202,P63010,Q99623,Q9GZP9,O75027,P05141,Q9Y666,Q9UBV2,Q4KMQ2,P35613,Q8IYU8,P40855,P04920,Q8WWC4,Q99797,P12235	78
Sphingolipid metabolism	0.8309177598801263	4.844919973281734	1.2666272217742858e-06	0.0017843516620632	0.0001984382647447	29	P16278,P51648,P06280,O43681,O15121,Q06136,P10619,Q16739,P27544,O95470,P17900,Q96G23,Q13510,P07602,Q9NZJ7,Q5SGD2,O15269,P04062,Q8TCT0	19
Metabolism of lipids	0.437017297467541	4.413269105745881	1.018213024339687e-05	0.0142543082215167	0.0006157519603188	195	O75845,Q9BY49,Q9NZ01,P16278,O95864,Q96N66,O95772,P51648,Q9H7Z7,Q16850,P50897,P14324,P35790,Q53H12,P06865,Q9NQZ5,Q96PE3,P06280,O43681,P38435,Q15165,Q9P035,P23786,Q9NPH0,O15121,Q06136,Q9UMR5,O00116,P10619,P30536,O15254,Q9NUQ2,Q16739,P27544,O43772,Q10713,Q8NF37,O95470,O43808,P37268,Q15392,P17900,Q96G23,Q13510,P07602,P09960,Q8NCC3,Q8NAN2,Q53GQ0,Q8N2A8,Q9HCL2,Q9UBM7,Q9NZJ7,O75448,Q709F0,Q9Y6K0,Q5SGD2,O15269,P04062,Q8IV08,Q14739,Q15800,Q8TCT0,Q15067,Q6Y1H2	65
Mitochondrial protein import	0.6698969902162617	3.996868650373813	6.418589173162736e-05	0.0865302443708023	0.0014345235850933	35	Q99595,Q9NS69,O60830,Q9Y512,Q8N4H5,Q9UJS0,Q15388,Q9Y5J9,P12236,P21796,O14925,P06576,O75431,Q10713,O43615,Q3ZCQ8,O96008,Q13505,Q9Y5J7,Q9Y5J6,P12235	21
Vitamin d calciferol metabolism	0.9500891265597156	3.9776492516014494	6.959993596611369e-05	0.0934774063027844	0.0014647150703316	2	P04062	1
Hs gag degradation	0.9447415329768276	3.952775530729246	7.724989763269186e-05	0.1032037268912772	0.0015331181782372	2	P16278	1
Sulfide oxidation to sulfate	0.9364230540701148	3.913930974784149	9.0805603306654e-05	0.1201833224722618	0.0017539164474299	2	Q9UBX3	1
Zinc transporters	0.915032679738563	3.813180903014476	0.0001371896188158	0.1758894805684801	0.0023028257444083	2	Q8TAD4	1
Metal ion slc transporters	0.915032679738563	3.813180903014476	0.0001371896188158	0.1758894805684801	0.0023028257444083	2	Q8TAD4	1
Glycerophospholipid biosynthesis	0.6549721740358843	3.787199839749688	0.0001523545627077	0.1933265177611737	0.0025272933343292	33	Q9NUQ2,Q8NAN2,Q8N2A8,Q9HCL2,Q9UG56,O95674,Q96N66,Q8NF37,Q8NCC3,Q92604,Q9NPH0,Q9Y6K0,Q8IV08,P35790,Q53H12,O14735,Q9NQZ5	17
Metabolism of fat soluble vitamins	0.9699912402959364	3.734069481920206	0.0001884104786111	0.233318489527189	0.0029562685205488	3	Q8N0U8	1
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.510203060125812	3.603471252572752	0.0003139954896587	0.3577663901157699	0.0041444463289639	62	Q86Y39,O14949,O43676,Q7L592,O43819,P22695,O75964,Q9P0S2,P24539,Q9UDW1,P13073,P03886,Q16134,P06576,Q9NPL8,P21912,P00403,Q9Y6M9,O96000	19
Phospholipid metabolism	0.5420013064595715	3.603047829093802	0.0003145076292192	0.3582301360557416	0.0041444463289639	53	Q96N66,P35790,Q53H12,O14735,Q9NQZ5,P48651,Q96PE3,O95674,Q9NPH0,Q9NUQ2,Q10713,Q8NF37,Q8NCC3,Q8NAN2,Q8N2A8,Q9HCL2,Q9UG56,Q92604,Q9Y6K0,Q8IV08	20
Slc mediated transmembrane transport	0.7095744415033812	3.593210483846943	0.0003266285295921	0.3691085481765567	0.0042251947405963	24	Q8TB61,P30825,P55011,Q8TAD4,P05141,Q70HW3,Q9Y666,P53985,P04920,P12235,Q9UBX3,Q9Y6M7,Q9UPY5,Q9Y289,P11166,P12236,P35613,Q15043	18
Bicarbonate transporters	0.8636363636363662	3.565820337612395	0.0003627198058586	0.4004210993913479	0.0046075218582047	2	Q9Y6M7	1
Glycosphingolipid metabolism	0.8398036431186303	3.534915918124275	0.0004079049320087	0.4374432653988157	0.0049157773857459	16	Q16739,P06280,O43681,P16278,Q9NZJ7,P17900,P04062,Q13510,P07602,P10619,Q8TCT0	11
Acyl chain remodelling of pg	0.8535353535353567	3.5162954264361415	0.0004376137541299	0.4605312631344274	0.0052216946611502	2	Q8NF37	1
Cytochrome p450 arranged by substrate type	0.8434343434343458	3.4664614918351666	0.0005273572694355	0.5246813621762612	0.0060948668024926	2	Q16850	1
Respiratory electron transport	0.5271492493673534	3.3942203938966893	0.0006882428018608	0.6212036097021527	0.0072964086513068	52	P22695,Q9NPL8,Q86Y39,P21912,P00403,Q9P0S2,Q9Y6M9,O96000,O14949,O43676,Q9UDW1,P13073,P03886,Q7L592,O43819	15
Ion channel transport	0.613694072547495	3.390693188202443	0.000697160998929	0.6259402823368768	0.0073357985708203	32	Q9NW15,Q9Y487,Q9HD20,P05023,P51798,P35670,P16615,Q9C0H2,Q93050,Q96PU5,P51790	11
Proton coupled monocarboxylate transport	0.8166963755199065	3.333024633866089	0.0008590733578623	0.7023431683586603	0.0081456969671645	2	P35613	1
Synthesis of pg	0.8751857355126305	3.299215500708736	0.0009695544941843	0.7453168335350921	0.0089938936631574	3	Q8N2A8,Q8IV08	2
Activation of kainate receptors upon glutamate binding	0.8062982768865139	3.2805226076853806	0.0010361496035591	0.768164765672988	0.0093651983398614	2	Q12959	1
G protein activation	0.8062982768865139	3.2805226076853806	0.0010361496035591	0.768164765672988	0.0093651983398614	2	P29992	1
Class b 2 secretin family receptors	0.8062982768865139	3.2805226076853806	0.0010361496035591	0.768164765672988	0.0093651983398614	2	Q9Y3E5	1
Sumoylation of intracellular receptors	0.8027332144979225	3.2624418735241147	0.0011045682241443	0.789506810434909	0.0099200076181121	2	P04150	1
Cation coupled chloride cotransporters	0.7994652406417138	3.245831694312403	0.0011710805158642	0.8083704390671654	0.0103336816363469	2	Q9Y666	1
Sphingolipid de novo biosynthesis	0.8258380979598968	3.2187309568010405	0.0012875923296982	0.8374346175220959	0.0108712885321825	13	P27544,O95470,P51648,Q5SGD2,O15121,Q96G23,Q06136	7
Synthesis of pe	0.856760772659733	3.211898615762722	0.0013186090019674	0.844399830180057	0.0110668969807982	3	P35790,Q9Y6K0	2
Hs gag biosynthesis	0.7884729649435581	3.1897052170784863	0.0014241798300764	0.8659476471868974	0.0118822104166144	2	Q7LGA3	1
N glycan antennae elongation in the medial trans golgi	0.7834224598930507	3.1637840271251254	0.0015573231337533	0.8889236194036669	0.0126926336334809	2	Q16706	1
Reactions specific to the complex n glycan synthesis pathway	0.7834224598930507	3.1637840271251254	0.0015573231337533	0.8889236194036669	0.0126926336334809	2	Q16706	1
Noncanonical activation of notch3	0.7694592988710678	3.0916770935104574	0.0019902922325305	0.9397413078795248	0.0145404769319589	2	Q92542	1
Ptk6 regulates proteins involved in rna processing	0.8175334323922738	3.022766156982733	0.0025047571240568	0.9708744062020378	0.0167987754581714	3	O75525,P23246	2
Adp signalling through p2y purinoceptor 1	0.8065378900445771	2.9689417997107195	0.0029882718888196	0.9852979952982156	0.0183994033329071	3	P29992,Q16539	2
Camk iv mediated phosphorylation of creb	0.7323232323232389	2.8966681281805764	0.0037714849312708	0.9951454896044876	0.0221574739712164	2	P52292	1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde	0.7323232323232389	2.8966681281805764	0.0037714849312708	0.9951454896044876	0.0221574739712164	2	P52292	1
Diseases associated with glycosaminoglycan metabolism	0.8507254211467048	2.8872435032121153	0.0038863333199585	0.9958738300627964	0.0225503291405004	4	Q8NCH0,Q96L58	2
Chondroitin sulfate dermatan sulfate metabolism	0.8507254211467048	2.8872435032121153	0.0038863333199585	0.9958738300627964	0.0225503291405004	4	Q8NCH0,Q96L58	2
Pre notch processing in golgi	0.8277858892085584	2.7800051147143807	0.0054358042288722	0.9995405089430652	0.0300567998537641	4	Q15363,P16615	2
Abc transporters in lipid homeostasis	0.7610698365527496	2.7424767337341076	0.0060977769563659	0.9998202936621584	0.0329420134424366	3	P28288,P40855	2
Transport of bile salts and organic acids metal ions and amine compounds	0.8171819262782357	2.729953624927616	0.0063343235501562	0.999871528492044	0.033718401529159	4	Q8TAD4,P35613,Q15043	3
O linked glycosylation of mucins	0.8165091624065726	2.726767802013426	0.0063958028904071	0.9998822615090796	0.0339025641935118	4	Q10472,O43505	2
Synthesis of pa	0.7714131154167	2.699630741540263	0.0069416474803247	0.9999457470095424	0.0355917198082106	11	Q9NUQ2,Q8N2A8,Q9HCL2,Q8NF37,Q9NPH0	5
Cristae formation	0.6394956878519009	2.69073714047388	0.0071294344854739	0.9999584456433468	0.0362906231932069	20	Q9BUR5,Q9NVH1,Q5XKP0,O75964,Q9Y512,Q13505,P24539,P56385,Q6UXV4,Q9NX63,P06576,Q16891,O75431	13
Class i peroxisomal membrane protein import	0.7628835269585794	2.654456412410129	0.0079436301499662	0.9999869306648655	0.0379678593608556	11	Q9NR77,P40855,Q8NBU5,P51648,Q9Y5Y5,Q9Y3D6,O75381,O43808,P28288,Q8TB36	10
Rac2 gtpase cycle	0.5008579578618724	2.6294054488038756	0.0085534313781756	0.9999945079715896	0.040607199472147	38	O15173,Q6IAA8,P02786,Q9Y512,Q13505,Q86XL3,Q86Y07,Q13153,P50402,Q9H0H5,P42167,Q14739,Q8TAA9,Q7L576,P42166,P49257	16
Mitochondrial calcium ion transport	0.6828269000800157	2.6214688459628723	0.008755176396618	0.9999958779365088	0.0412869522382322	16	P21796,Q96TA2,Q10713,Q8IYU8,Q9BPX6,O95202,Q8NE86,Q8WWC4,Q99623,P45880,Q9Y277	11
Rhod gtpase cycle	0.5273006983100813	2.606050352963344	0.0091592995642724	0.9999976804107472	0.0430487079520803	31	O15173,O60879,Q8NHP6,Q86Y07,P50402,Q96C19,P20700,Q9H0H5,P42167,Q14739,Q8TAA9,Q9Y6M7,Q5JTV8,P42166,P49257	15
The citric acid tca cycle and respiratory electron transport	0.380308854360162	2.5651323373711925	0.0103136460129416	0.999999551677182	0.0470622682143937	94	Q86Y39,O14949,O43676,O95563,Q7L592,P48163,O43819,P35613,P21796,P22695,O75964,Q9P0S2,P24539,Q9UDW1,Q9H9P8,P13073,P03886,Q16134,P06576,Q9NPL8,P21912,P00403,O75880,Q15118,Q9Y6M9,Q13423,P53985,O96000,P56385,P11177,P31930,Q9BQ95	32
Sialic acid metabolism	0.7682260836984796	2.494864558255894	0.0126005216205946	0.9999999828217162	0.054666878415503	4	P10619	1
Pink1 prkn mediated mitophagy	0.8063683316906758	2.477807827624812	0.0132192323177486	0.9999999929017076	0.0571752072638823	8	P21796,Q9NS69,O96008,Q8N4H5,Q8IWA4	5
Degradation of cysteine and homocysteine	0.7636972715307859	2.472779167150849	0.0134066957916567	0.9999999945698632	0.0578086882759511	4	Q9UBX3	1
Peptide ligand binding receptors	0.8244581431320306	2.4528912529683655	0.014171317329169	0.999999998180114	0.059468920934906	7	P07602,P42892,P05067	3
Class a 1 rhodopsin like receptors	0.8244581431320306	2.4528912529683655	0.014171317329169	0.999999998180114	0.059468920934906	7	P07602,P42892,P05067	3
Glycosaminoglycan metabolism	0.6654798263076341	2.4436698427292947	0.0145387245330939	0.9999999989240704	0.0608296783135383	15	Q8TB61,P16278,Q96L58,Q8NCH0,Q7LGA3,P54802,P06865	7
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.6961414196164865	2.441651590139865	0.0146202488354139	0.999999999042534	0.0609897954376734	12	O43681,P46379,P09601,P50402,P51648,P05067	6
Rhog gtpase cycle	0.4904227611291317	2.436114144423672	0.0148459989636811	0.9999999993068664	0.0617488452471692	35	O15173,Q6IAA8,P02786,Q96JJ3,Q86XL3,O95202,Q86Y07,P50402,Q13190,P42167,Q14739,Q8TAA9,Q7L576,P05556,P42166,P49257	16
Heparan sulfate heparin hs gag metabolism	0.8008169142842558	2.4215892573366364	0.015452805627665	0.99999999970925	0.063523195145795	5	Q7LGA3,P54802,P16278	3
Endosomal vacuolar pathway	0.752778061431667	2.419292605334893	0.0155507255723741	0.9999999997472948	0.0637398926076963	4	Q9UIQ6,P10321	2
Inla mediated entry of listeria monocytogenes into host cells	0.6414141414141492	2.3984261183237554	0.0164656978061246	0.99999999993189	0.0667144652489531	2	O60716	1
Mitophagy	0.7102589114792809	2.3704683299981735	0.0177655658673641	0.9999999999894472	0.0701665206526145	11	P21796,Q9NS69,O96008,Q8N4H5,Q8IWA4	5
O linked glycosylation	0.7836187549209568	2.341053061244734	0.0192294339673693	0.9999999999987116	0.0739130519085025	5	Q10472,O43505	2
Mucopolysaccharidoses	0.736920332936972	2.34101580025453	0.0192313532173697	0.9999999999987152	0.0739130519085025	4	P54802,P34059,P16278	3
Alpha oxidation of phytanate	0.7834998371781117	2.3404935867183694	0.0192582691663028	0.999999999998764	0.0739130519085025	5	Q9BY49,P51648	2
Signalling to ras	0.6832476563013963	2.3397473909992037	0.0192967867448965	0.9999999999988304	0.0739130519085025	3	Q16539	1
Amino acid transport across the plasma membrane	0.7366230677764491	2.339541652578029	0.0193074185072894	0.9999999999988484	0.0739130519085025	4	P30825,Q15758,Q9UPY5	3
Synthesis secretion and deacylation of ghrelin	0.683078348965773	2.338849903807493	0.0193432029462676	0.999999999998906	0.0739130519085025	3	P67812	1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip	0.683078348965773	2.338849903807493	0.0193432029462676	0.999999999998906	0.0739130519085025	3	P67812	1
Long term potentiation	0.7327586206896501	2.320354985297551	0.0203216818879545	0.9999999999997322	0.0766138274385453	4	Q12959,P07196,Q14168	3
Unblocking of nmda receptors glutamate binding and activation	0.7327586206896501	2.320354985297551	0.0203216818879545	0.9999999999997322	0.0766138274385453	4	Q12959,P07196,Q14168	3
Ras activation upon ca2 influx through nmda receptor	0.7327586206896501	2.320354985297551	0.0203216818879545	0.9999999999997322	0.0766138274385453	4	Q12959,P07196,Q14168	3
Pregnenolone biosynthesis	0.6784582922345275	2.3143232792208592	0.0206499957758603	0.9999999999998332	0.077580822816187	3	O95772	1
Stimuli sensing channels	0.6999253038689168	2.3136264883213093	0.0206882194176498	0.999999999999842	0.077580822816187	11	Q9NW15,P51798,Q9C0H2,Q96PU5,P51790	5
Ire1alpha activates chaperones	0.519001982192168	2.290572072214008	0.0219881757254853	0.9999999999999756	0.0809486364828574	26	Q9NWM8,O76024,O95070,O14773,P43307,Q9Y5M8	6
Tp53 regulates transcription of death receptors and ligands	0.6179441473559208	2.2647972869049924	0.0235251220075425	0.9999999999999972	0.0846873143162123	2	P04637	1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis	0.617944147355921	2.2647972869049924	0.0235251220075425	0.9999999999999972	0.0846873143162123	2	O00767	1
Synthesis of very long chain fatty acyl coas	0.7378566334173231	2.2558818217081664	0.0240780332662815	0.9999999999999988	0.0855164405679017	9	Q53GQ0,Q9P035,Q9NZ01,Q6Y1H2	4
Ras processing	0.8102152267971517	2.2460744543104263	0.0246992393064904	0.9999999999999996	0.0870648185553787	6	O43924,P49354,O60725	3
Transport of inorganic cations anions and amino acids oligopeptides	0.6827594742712391	2.2184198158693045	0.0265262212445061	1.0	0.0910352699767756	11	P30825,Q15758,P55011,Q70HW3,P04920,Q9UBX3,Q9Y6M7,Q9UPY5,Q9Y666	9
Heme degradation	0.75752803036621	2.2174475838397716	0.0265925211414448	1.0	0.0910352699767756	5	P30519	1
Visual phototransduction	0.7739365160665435	2.2160108920202677	0.0266907561966067	1.0	0.0910352699767756	7	P49354,Q6NUM9	2
Elastic fibre formation	0.6060606060606154	2.1963449512980704	0.0280672625963351	1.0	0.093336887407624	2	P05556	1
Molecules associated with elastic fibres	0.6060606060606154	2.1963449512980704	0.0280672625963351	1.0	0.093336887407624	2	P05556	1
Attachment of gpi anchor to upar	0.7046194762295089	2.1793742443270285	0.029303877853779	1.0	0.0969917083892688	4	Q92643,Q9H490	2
Cholesterol biosynthesis	0.6192582990382205	2.1572950558403448	0.030982682001301	1.0	0.1013586580553004	15	Q9UBM7,P37268,Q15392,Q14739,Q15800,Q16850,O75845	7
Wax and plasmalogen biosynthesis	0.6967895362663425	2.1397489034369808	0.032375064592941	1.0	0.104308379097859	4	O00116,Q6IAN0,O15228	3
Processing of smdt1	0.6686460527386823	2.139413712847877	0.0324021773367817	1.0	0.104308379097859	11	Q9Y4W6,Q96TA2,Q10713,Q8IYU8,Q9BPX6,Q8NE86,Q8WWC4,Q99623,P35232	9
Gpcr ligand binding	0.7142697777298477	2.134741504270431	0.0327821307722646	1.0	0.1052911261705994	9	Q9NZJ7,Q9Y3E5,P07602,P42892,P05067	5
Activation of ppargc1a pgc 1alpha by phosphorylation	0.6421991084695408	2.1194270840383624	0.0340543899173655	1.0	0.1069414026358249	3	P54619,Q16539	2
Organelle biogenesis and maintenance	0.3504500040668915	2.1105548097234856	0.0348105953941668	1.0	0.1085030579012092	97	Q9H6D7,Q13561,Q9Y512,O95684,Q9BUR5,Q5XKP0,O75964,O75935,P24539,P06576,O75431,O43924,Q9NVH1,Q10713,Q68CZ6,A6NIH7,Q6UXV4,P41208,Q16891,Q92973,Q13505,O94927,P56385,Q9NX63,O43805,A0AVF1	26
Cargo concentration in the er	0.6192085060101727	2.0969689420545565	0.0359963247660606	1.0	0.1108183797383089	14	Q96PC5,Q15363,Q13190,P49755,Q9HCU5,P49257,O75396	7
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain	0.6353640416047559	2.082213130293802	0.0373230064646405	1.0	0.1136618555402661	3	P53611,Q92696	2
Constitutive signaling by overexpressed erbb2	0.6347696879643401	2.078970089680239	0.0376200996996236	1.0	0.1143196995182529	3	P62993,Q16543	2
Transport of vitamins nucleosides and related molecules	0.7238684460925446	2.073894665561181	0.0380890945850056	1.0	0.1152494219170685	8	Q8TB61,P05141,P12235,Q9Y289,P12236	5
Mitochondrial biogenesis	0.4586227201241525	2.0738900293420355	0.0380895252576978	1.0	0.1152494219170685	33	Q9BUR5,Q9NVH1,Q5XKP0,O75964,Q9Y512,Q13505,P24539,P56385,Q6UXV4,Q9NX63,P06576,Q16539,Q16891,O75431	14
Er quality control compartment erqc	0.7263071968848442	2.06729065668041	0.0387067741296411	1.0	0.1168662773507367	5	Q9GZP9,Q9UBV2	2
Synthesis of pc	0.7694641965783358	2.059962687054229	0.0394021080417388	1.0	0.1173588033960099	6	Q8NF37,Q9NQZ5,Q9Y6K0	3
Rhoa gtpase cycle	0.4188272405679096	2.0475514993730024	0.0406039658097521	1.0	0.1202764533440136	48	Q96CS3,P41440,O15173,Q96HY6,P02786,Q15904,P51572,O75955,Q13190,Q9Y4F1,P42167,P28288,Q8TAA9,P30519,Q14739,P42166	16
Immunoregulatory interactions between a lymphoid and a non lymphoid cell	0.7366855102647843	2.0373333577623347	0.0416166471826602	1.0	0.1227604027773031	7	Q9BZM4,P10321,Q5KU26,P04439,P05556,P78310	6
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.7179069873978434	2.0264771898772245	0.0427159078983467	1.0	0.1254730089516984	5	P12235,P12236,P05141	3
Complex i biogenesis	0.4723077276581255	2.006877567991633	0.0447627009133033	1.0	0.1288069556893015	28	Q9NPL8,Q86Y39,Q9Y6M9,O96000,O43676,P03886	6
Initiation of nuclear envelope ne reformation	0.5623335679421484	1.9878277662893375	0.0468307417462083	1.0	0.1328598508292833	18	Q86Y07,Q86XL3,P50402,P42167,Q14739,P42166,P02545	7
Synaptic adhesion like molecules	0.7529342769199237	1.9834185866526592	0.0473206926840716	1.0	0.1339802744669499	6	P41440,O95197,Q12959,O75955	4
The phototransduction cascade	0.7080116515640196	1.978178821801258	0.0479085369971048	1.0	0.1351577963892936	5	P49354	1
Keratan sulfate degradation	0.7079758474559719	1.9780036349736032	0.047928296591948	1.0	0.1351577963892936	5	P34059,P06865,P16278	3
Antigen presentation folding assembly and peptide loading of class i mhc	0.5669464031226759	1.947834423480746	0.0514347783921513	1.0	0.1438949157399473	17	Q9NZ08,P10321,P51572,Q03518,P04439,Q03519,Q6P179	7
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling	0.6957749276943244	1.932308597894287	0.0533214278413374	1.0	0.1482903614522401	8	P07196,P51812,Q14168	3
Ion transport by p type atpases	0.6313249972582022	1.9273812976623703	0.0539321286343414	1.0	0.149693506642562	11	P05023,P16615,Q9HD20	3
Depolymerisation of the nuclear lamina	0.692168896815669	1.91399161814687	0.0556212267457016	1.0	0.152877055967718	8	P50402,P20700,P42167,P42166,P02545	5
G2 m dna replication checkpoint	0.6502886758050899	1.9009379903161303	0.057310135275139	1.0	0.1563003689321974	4	Q99640	1
Incretin synthesis secretion and inactivation	0.6466262143341786	1.8818823983310096	0.0598519848159342	1.0	0.1619794598665399	4	P67812	1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1	0.6466262143341786	1.8818823983310096	0.0598519848159342	1.0	0.1619794598665399	4	P67812	1
Rac3 gtpase cycle	0.425711183074161	1.8364374433914636	0.0662929860730576	1.0	0.1743901312742748	36	O15173,Q15758,Q6IAA8,P02786,Q86Y07,Q13153,P50402,Q9UQB8,Q9H0H5,P42167,Q14739,Q8TAA9,Q7L576,P05556,P42166,P49257	16
Gap junction assembly	0.5853418400883912	1.8054356974643948	0.0710065293152173	1.0	0.1847217829049011	3	Q9BVA1	1
Transport of connexons to the plasma membrane	0.5853418400883912	1.8054356974643948	0.0710065293152173	1.0	0.1847217829049011	3	Q9BVA1	1
Keratan sulfate keratin metabolism	0.7139745118153746	1.8007060063793583	0.0717492304084461	1.0	0.1856264493135946	6	O43505,P34059,P06865,P16278	4
Signaling by mapk mutants	0.5362448009506953	1.7837102409434773	0.0744707611959432	1.0	0.1916127249749633	2	Q99956	1
Metabolism of steroid hormones	0.6673990970520478	1.777535123020586	0.0754802373202301	1.0	0.1931526944129301	5	Q53GQ0,O95772	2
Phosphorylation of emi1	0.6263399312682647	1.775714017579516	0.0757800657751968	1.0	0.1933043360732727	4	P53350,Q12834	2
Mastl facilitates mitotic progression	0.6246353807240124	1.766746649879491	0.0772706669890732	1.0	0.1959561878679735	4	P30153,P30154	2
Basigin interactions	0.67866706337399	1.7525322381631483	0.0796823314783869	1.0	0.2006287274723672	7	P53985,Q9UPY5,P08195,P05556,P54709,P35613	6
Myoclonic epilepsy of lafora	0.5279263220439814	1.733416699612373	0.0830216315182581	1.0	0.207243091301667	2	P13807	1
Integrin cell surface interactions	0.657518820847802	1.7281627636181704	0.0839590475455911	1.0	0.2091559311648118	5	Q08722	1
Ra biosynthesis pathway	0.6091511191834231	1.684970881885144	0.0919941895315215	1.0	0.2259787582568733	4	Q8NBN7	1
Tp53 regulates transcription of genes involved in cytochrome c release	0.5196078431372675	1.682905637818946	0.0923933600269109	1.0	0.226564587196425	2	P04637	1
Assembly and cell surface presentation of nmda receptors	0.6432279317439508	1.6623691314535571	0.0964387842775713	1.0	0.2349944275157772	8	P07196,Q12959,Q14168,Q9BVA1	4
Diseases of glycosylation	0.490671036671957	1.6233331183976	0.1045182134843851	1.0	0.2497808152762425	20	P16278,Q13724,O43505,Q8NCH0,Q96L58,Q9BT22,Q2TAA5,P10619,P06865	9
Nuclear envelope ne reassembly	0.3750923376972037	1.6048378000124193	0.1085295048748691	1.0	0.2584908815431849	50	Q8NFH3,O95067,Q8NFH5,Q86XL3,P50402,P52948,Q12769,Q9BTX1,Q96FZ7,O43633,O75694,Q8IXJ6,Q9Y2U8,P20700,Q8N1F7,Q7Z3B4,Q8WUM0,Q8NFH4,P57740,P42167,P42166,Q9BW27,P02545,Q92973,Q86Y07,Q5SRE5,Q14739,P30153,Q96EE3,Q9BVA1	30
Maturation of sars cov 2 spike protein	0.575194149357803	1.6005752456694513	0.1094710286558053	1.0	0.2598554720617602	11	P46977,P27824,Q16706,Q13724	4
Purinergic signaling in leishmaniasis infection	0.6266884640483951	1.5728328854941676	0.1157575188019082	1.0	0.2715775399512322	5	P09601	1
Iron uptake and transport	0.491683872448792	1.5568982571214005	0.1194946433299861	1.0	0.2789527269789412	19	Q9Y487,Q93050,P30519	3
Ros and rns production in phagocytes	0.5861741672075834	1.5517172107838744	0.1207299027399573	1.0	0.2809062093454452	10	Q9Y487	1
Signal attenuation	0.5398779169251229	1.5477181277211325	0.1216901756579691	1.0	0.2822091244699613	3	P62993	1
Protein protein interactions at synapses	0.5238205257491751	1.5398198295865957	0.123604276969135	1.0	0.2852406391595423	15	P41440,O95197,Q14168,O75955,Q12959	5
Selective autophagy	0.4130726090881146	1.5350451788365895	0.1247727308670061	1.0	0.2869976354363436	30	P21796,Q9NS69,O96008,P08670,Q8N4H5,Q8IWA4	6
Apc c cdc20 mediated degradation of cyclin b	0.5372816681973094	1.533307496715386	0.1252001083637035	1.0	0.2875116494997101	13	Q12834,Q9UJX3,Q96DE5,Q9UJX2,Q9UJX4	5
Peroxisomal lipid metabolism	0.5614569867859946	1.5193421358599684	0.1286763988363384	1.0	0.2936765628543341	11	Q9BY49,P51648,Q15067,O15254	4
Negative regulation of nmda receptor mediated neuronal transmission	0.6551228679899406	1.5191775419651057	0.1287178126553039	1.0	0.2936765628543341	6	P07196,Q14168,Q14012	3
Activation of ampk downstream of nmdars	0.6142366919673832	1.5096080380028851	0.1311434691149884	1.0	0.2982456313744091	5	P54619,Q9BVA1,P54646	3
Ptk6 regulates rho gtpases ras gtpase and map kinases	0.573213546486846	1.4931876216452689	0.1353880813790851	1.0	0.3052150321880207	4	Q96JJ3	1
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling	0.4881164587047077	1.4899104018053992	0.1362477961739729	1.0	0.3063945655586952	2	P51617	1
Carboxyterminal post translational modifications of tubulin	0.6091729735705307	1.4838258942230926	0.1378551156507321	1.0	0.3088312322887608	5	Q9UPW5,Q9BVA1,Q14166	3
Slc transporter disorders	0.3980654830480201	1.483263594337957	0.1380043908339858	1.0	0.3088312322887608	33	Q8NFH3,Q8NFH5,P52948,Q12769,P35613,Q9BTX1,O75694,Q8N1F7,Q7Z3B4,Q8WUM0,Q8NFH4,P57740,P11166,Q9BW27,P53985,Q5SRE5,Q99567,P08195,Q96EE3	19
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.5549078644544515	1.4804715507908996	0.1387474475275141	1.0	0.3090582954404343	11	Q12834,Q9UJX3,Q96DE5,Q9UJX2,Q9UJX4	5
Response to elevated platelet cytosolic ca2	0.394259973051848	1.4666445472994305	0.1424727750424301	1.0	0.3158594541035008	34	Q8NBM8,P13473,Q9NZJ7,Q08380,O43852,Q92520,Q6UXV4,O94919,P07602,Q8NBX0,Q9Y6I9,P05067	12
Platelet calcium homeostasis	0.5243594666210477	1.458647346267145	0.1446621951333826	1.0	0.3181447547412543	3	P16615	1
Reduction of cytosolic ca levels	0.5243594666210477	1.458647346267145	0.1446621951333826	1.0	0.3181447547412543	3	P16615	1
N glycan trimming in the er and calnexin calreticulin cycle	0.5038694535421614	1.4579658473167276	0.1448499569665902	1.0	0.3181447547412543	16	Q13724,Q9BUN8,Q9GZP9,Q9UBV2,P27824	5
Diseases associated with n glycosylation of proteins	0.6424724634077799	1.457938849834724	0.1448573989672945	1.0	0.3181447547412543	6	Q9BT22,Q2TAA5,Q13724	3
Tp53 regulates transcription of caspase activators and caspases	0.5197622585438352	1.4321746028825464	0.1520938581648165	1.0	0.3309449691549249	3	P42575,P04637	2
Disinhibition of snare formation	0.478015448603698	1.427498770910769	0.1534361792008112	1.0	0.3328384810356058	2	Q12846	1
Nuclear envelope breakdown	0.3775260846858037	1.4203657370630332	0.1555012323049525	1.0	0.3357683576569418	41	Q8NFH3,O95067,Q8NFH5,P53350,P50402,P52948,Q12769,Q9BTX1,O75694,Q9Y2U8,P20700,Q8N1F7,Q7Z3B4,Q8WUM0,Q8NFH4,P57740,P42167,P42166,Q9BW27,P02545,Q86Y07,Q5SRE5,Q99567,Q96EE3	24
Recruitment of mitotic centrosome proteins and complexes	0.3915504826583385	1.4183054538538455	0.1561016051034156	1.0	0.3365493321036942	33	Q9H6D7,Q13561,O94927,O75935,O95684,P41208,Q9BSJ2,O43805	8
Defective ripk1 mediated regulated necrosis	0.476232917409402	1.4164640664754322	0.1566396777528762	1.0	0.3366797951700541	2	Q12933	1
Tnfr1 induced proapoptotic signaling	0.476232917409402	1.4164640664754322	0.1566396777528762	1.0	0.3366797951700541	2	Q12933	1
Intra golgi traffic	0.4532497089274478	1.413433453391483	0.1575283151279078	1.0	0.3380744662562406	21	Q13190,O95249,O60476,Q96MW5,Q8TBA6,Q16706,O00461,O95721	8
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.4792285766412877	1.400268807503169	0.1614328378807243	1.0	0.3459275097444094	18	O76024,O43852,Q02818,O43493,Q07065,P05067	6
Activated notch1 transmits signal to the nucleus	0.5553886431212509	1.3972102812935534	0.1623503458921704	1.0	0.3468393753150914	4	Q96J02,Q92542	2
Rab geranylgeranylation	0.4255342389435998	1.395233695126508	0.1629453791855799	1.0	0.3475839404715094	24	P61026,Q9UL25,P20339,P20337,Q9H0U4,P61019,Q92696,P53611,Q969Q5,P51151,Q14964,P62820	12
Transferrin endocytosis and recycling	0.5195367842757014	1.3821384776999748	0.1669291859654416	1.0	0.3534263513977035	12	Q9Y487,P02786,Q15904,Q93050	4
Metabolism of steroids	0.3717464075685769	1.3736710649052273	0.169543823713123	1.0	0.3578694482567417	42	Q53GQ0,Q15800,Q9HCL2,Q9UBM7,P38435,O95772,P37268,Q15392,P04062,Q14739,Q16850,P14324,P30536,O75845	14
Insulin receptor recycling	0.5359714050649431	1.3676393857907108	0.1714249817006945	1.0	0.3612273146680654	11	Q9Y487	1
Free fatty acids regulate insulin secretion	0.5066987291649382	1.356769671368426	0.1748544070113902	1.0	0.3668820147113991	3	P29992	1
Neuronal system	0.3490868195856451	1.3532593328455536	0.1759727961761075	1.0	0.3676217971888554	52	P54619,P41440,O95197,Q14168,Q96RD7,P51812,Q14254,P21964,O75955,Q12959,P63010,P63218,P52292,O75915,P07196,Q14012,Q9BVA1,P10586	18
Metabolism of porphyrins	0.5498709836434049	1.3448004670334688	0.178689679417308	1.0	0.3716112802041362	10	P50336,P09601,P22830,P33527,P30519,P36551	6
Unwinding of dna	0.5478114606825203	1.3330042437416465	0.1825304111533121	1.0	0.3784821760678972	10	O75419,P33993,Q9Y248,Q14566	4
Cytoprotection by hmox1	0.320874778489267	1.3293711338527865	0.1837255564208231	1.0	0.37987571607497	67	P00403,Q9P0S2,P09601,P49721,P13073,P28070,P30519,P28072,O43819	9
Unfolded protein response upr	0.3683570183179992	1.32028220301111	0.1867408152632257	1.0	0.3839098583158228	41	Q9NWM8,P43307,O95070,O14773	4
Post translational modification synthesis of gpi anchored proteins	0.5780689542812789	1.320159784383919	0.1867816757479818	1.0	0.3839098583158228	8	Q6YHK3,Q92643,Q9H490,Q96S52	4
Miscellaneous transport and binding events	0.5766143299776755	1.3124562544638874	0.1893662368652264	1.0	0.3871790495804667	8	Q9HD23,Q8TDW0,Q8N4V1	3
Runx1 regulates transcription of genes involved in differentiation of myeloid cells	0.4587046939988266	1.3076867166513928	0.1909795906092011	1.0	0.3885731930143918	2	P17931	1
Synthesis of pips at the early endosome membrane	0.5372865761511577	1.2993308358631666	0.1938304163711817	1.0	0.3926736883381698	4	Q96PE3,Q9BTU6	2
Activation of nmda receptors and postsynaptic events	0.4256262766587522	1.2715764899773858	0.2035236343317861	1.0	0.4074422796435404	22	P54619,Q14168,P51812,Q12959,P52292,P07196,Q14012,Q9BVA1	8
Phosphorylation of the apc c	0.4946696049849124	1.2615242908866655	0.2071200139246323	1.0	0.4122633042502409	13	Q9H1A4,Q9UJX3,P30260,Q96DE5,Q9UJX4,Q9UJX2	6
Diseases of carbohydrate metabolism	0.5488276251351166	1.246230692220151	0.2126797141742338	1.0	0.4215668217931466	9	P34059,P54802,P10253,P16278	4
Inflammasomes	0.5984847905060567	1.2436957756986	0.2136115513103587	1.0	0.4218379374616327	6	P09601,P05067	2
The nlrp3 inflammasome	0.5984847905060567	1.2436957756986	0.2136115513103587	1.0	0.4218379374616327	6	P09601,P05067	2
Nicotinamide salvaging	0.526856495940377	1.2428123065233414	0.2139370064920567	1.0	0.4218897610542657	4	P43490	1
Maturation of sars cov 1 spike protein	0.5262575563003156	1.239565115678028	0.2151362901703994	1.0	0.4236622474026024	4	Q13724	1
Cell surface interactions at the vascular wall	0.464000429945674	1.234462651994312	0.217030555446851	1.0	0.4267964897908785	17	Q92896,P35613,P62993,P53985,Q08722,Q9UPY5,P08195,P05556,P54709,P78310,P05026	11
Dopamine neurotransmitter release cycle	0.4447415329768344	1.2207950798438607	0.2221636171715633	1.0	0.4338652357505599	2	O14936	1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest	0.4435531788473037	1.213395371365434	0.224978695132425	1.0	0.436341073090398	2	P04637	1
Metabolism of folate and pterines	0.5252530809734374	1.2035694450038612	0.2287560351906026	1.0	0.4412394112431596	10	P00374,Q9H2D1	2
Regulation by c flip	0.4763744427934639	1.181081349567897	0.2375704081711531	1.0	0.455747313634457	3	Q12933,P49327	2
Caspase activation via death receptors in the presence of ligand	0.4763744427934639	1.181081349567897	0.2375704081711531	1.0	0.455747313634457	3	Q12933,P49327	2
Gamma carboxylation hypusine formation and arylsulfatase activation	0.5033953437957063	1.172543549435541	0.2409788983299678	1.0	0.4591624954665604	11	P38435,O60725,O43681,Q9HA64	4
Translation of sars cov 1 structural proteins	0.5479779268195997	1.1605766227660483	0.2458141168202017	1.0	0.4652320868677643	8	Q10472,Q13724	2
Thromboxane signalling through tp receptor	0.5086637792174349	1.1441571990357888	0.2525584497769937	1.0	0.4729182127298288	4	P29992	1
Recruitment of numa to mitotic centrosomes	0.357022228670554	1.128556282716764	0.2590850615068496	1.0	0.4844959373006074	36	Q9H6D7,Q13561,O94927,O75935,O95684,P41208,Q9BSJ2,O43805	8
Ncam signaling for neurite out growth	0.5536371851069589	1.11872474669141	0.2632575844807654	1.0	0.4897007837966745	7	O15020,P62993,P13591	3
Tp53 regulates transcription of cell death genes	0.5702485413333579	1.105729083702857	0.2688437977470439	1.0	0.4981205713841419	6	Q92696,P53611,P04637	3
Formation of atp by chemiosmotic coupling	0.507919955460687	1.1040268891406275	0.2695814736764035	1.0	0.4988318607398017	10	O75964,P24539,P56385,P36542,P06576	5
Synthesis of pips at the golgi membrane	0.5361730447624209	1.097957492141293	0.2722230513178103	1.0	0.5024011810970059	8	Q10713,Q9NTJ5,Q9BTU6	3
Runx2 regulates osteoblast differentiation	0.4588410104011902	1.0794608830049646	0.280382322640522	1.0	0.512248201253399	3	P28482,P27361	2
Signaling by ptk6	0.4606339175032389	1.0779523766667596	0.2810550094970754	1.0	0.512248201253399	14	O75525,P04150,Q07666,Q96JJ3,P46108,P23246	6
Smad2 smad3 smad4 heterotrimer regulates transcription	0.4582466567607742	1.0760203418515566	0.2819181589876862	1.0	0.512248201253399	3	P28482,P27361	2
Translation of sars cov 2 structural proteins	0.4262042687939362	1.0710091575806076	0.284165312065975	1.0	0.5153096629678513	19	P04843,Q13724,P46977,Q16706,P27824,Q10472	6
Cd163 mediating an anti inflammatory response	0.4464113650652491	1.0076148772836375	0.3136393839812124	1.0	0.5490479774740097	3	Q16539	1
Rnd1 gtpase cycle	0.4464051442236227	0.9848408431996464	0.3247022549159397	1.0	0.5610663963621018	14	P02786,O75976,Q14254,P51648,P38159,Q8TAA9,Q9BXS4,O43396	8
Peptide hormone metabolism	0.4140126041970595	0.9803483225855012	0.3269142093619153	1.0	0.5621329697564641	19	O75787,P67812,Q8TAD4,Q15005	4
Collagen biosynthesis and modifying enzymes	0.4699337415720191	0.9722659170040512	0.3309182750723631	1.0	0.5676335375328857	11	O75718,P13674,Q32P28,O15460	4
Rhoj gtpase cycle	0.3885065690713251	0.9690650041234422	0.332512757120555	1.0	0.5692916243237895	22	Q6IAA8,Q15758,P02786,Q13153,P42167,Q8TAA9,Q9Y6M7,P42166	8
Anchoring of the basal body to the plasma membrane	0.3447875114605482	0.9643141683243508	0.3348884396284777	1.0	0.5705376276000379	34	Q9H6D7,Q13561,O94927,O75935,O95684,P41208,O43805	7
Asparagine n linked glycosylation	0.2725790619080753	0.9630217198264794	0.3355366235255381	1.0	0.5705376276000379	127	Q9NYU1,Q15363,P24390,Q13561,P16278,Q86YN1,P49755,P46977,Q9H6U8,P04843,O75935,O95249,O15027,Q96MW5,P10619,Q12893,Q9HCU5,Q2TAA5,Q9GZP9,P62820,Q96PC5,Q13724,Q9BUN8,Q13190,Q9Y673,Q9BT22,O60476,Q16706,Q9UBV2,P27824,O75396	31
Role of second messengers in netrin 1 signaling	0.403149138443267	0.9624218716851822	0.3358377313867904	1.0	0.5705376276000379	2	Q00169	1
Signaling by fgfr4 in disease	0.4031491384432651	0.9624218716851703	0.3358377313867964	1.0	0.5705376276000379	2	P62993	1
Nicotinate metabolism	0.5066900669439275	0.9583569748262089	0.3378827830277409	1.0	0.5721870927713509	5	P43490	1
Rac1 gtpase cycle	0.3254399016253899	0.9398373379685904	0.3473010033395056	1.0	0.5857588692687835	47	Q6IAA8,Q15758,P02786,Q86Y07,Q13153,P50402,Q9UQB8,Q9Y4F1,Q9Y2U8,Q96F07,Q9H0H5,P42167,Q14739,Q8TAA9,Q7L576,P05556,P42166	17
Cobalamin cbl vitamin b12 transport and metabolism	0.5020502921924375	0.9347152613497262	0.349935059778022	1.0	0.5894963372604671	5	Q9NPF0,P33527	2
Aurka activation by tpx2	0.339925097678057	0.9150133001828676	0.3601846479004653	1.0	0.6010181698694155	34	Q9H6D7,Q13561,O94927,O75935,O95684,P41208,O43805	7
Maturation of sars cov 1 nucleoprotein	0.4279346210995561	0.9014442737597574	0.3673521503864165	1.0	0.6079419390197739	3	P49840,Q8IXQ6	2
Regulation of tp53 activity through methylation	0.4604637336504063	0.8842574864515146	0.3765572322947605	1.0	0.6173787180646656	4	Q13315,P04637,O96017	3
Rhoc gtpase cycle	0.3408658526417423	0.8810192688724996	0.3783073907793386	1.0	0.6195277828093698	32	P41440,P02786,O75955,Q13190,Q9H0H5,P42167,P28288,Q8TAA9,Q14739,P42166,P49257	11
Runx2 regulates bone development	0.4589774078477864	0.8763264474654975	0.3808525912651745	1.0	0.6218536306677749	4	P28482,P27361,Q96PK6	3
Ngf stimulated transcription	0.4172362555720673	0.8404992561672732	0.4006285184684492	1.0	0.6433783724835005	3	P50570,Q14839	2
Assembly of the hiv virion	0.3826500297088617	0.8366851072741631	0.4027695925038581	1.0	0.6446142172876731	2	Q9H9H4	1
Regulation of lipid metabolism by pparalpha	0.3705470524244955	0.8238094450719469	0.4100478400375349	1.0	0.6532965587038693	22	O60244,O75448,P23786,P50416,P37268,P48163,Q15067	7
G alpha i signalling events	0.3572461152956402	0.810270084831105	0.4177849647633436	1.0	0.6589423125184012	24	P07602,Q9NZJ7,P05067	3
Rho gtpase cycle	0.2584890600846267	0.8102483286540594	0.4177974662350714	1.0	0.6589423125184012	161	Q9Y512,O75976,Q96JJ3,Q8NHP6,Q86XL3,P08670,P51648,Q96C19,P50402,Q9UQB8,P38159,Q96F07,P30519,Q9BXS4,Q15758,P02786,Q8N684,O75955,P62995,Q9Y2U8,P20700,Q8TAA9,Q5JTV8,P49257,Q9H8V3,Q07065,Q96CS3,O15173,Q96HY6,O95202,Q13153,Q9H0H5,Q86YQ8,P28288,P42167,Q9Y6M7,Q7L576,P42166,O60879,P41440,Q6IAA8,Q9BT78,Q15904,Q13505,Q14254,Q86Y07,P07910,P51572,Q13190,Q9Y4F1,Q99707,Q14739,P05556,O43396	54
Abc family proteins mediated transport	0.2984155115859189	0.8077783424225246	0.4192181948474633	1.0	0.6604443069663948	55	P08183,O75027,P40855,P49721,P61289,P33527,Q9BUN8,P28070,P28288,P28072,Q9GZP9,Q9UBV2,O00231	13
Autophagy	0.308419559854418	0.8013669538400924	0.4229192403399353	1.0	0.6647894413370221	50	P21796,Q9NS69,P13473,O96008,P08670,Q8N4H5,Q15382,Q8IWA4	8
Amyloid fiber formation	0.4894974700759626	0.7937688035547945	0.4273300371055775	1.0	0.6688872418501469	7	Q9Y287,P05067	2
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.4392344291030297	0.7907472034965264	0.4290915246457223	1.0	0.670332941876452	11	Q96DE5,Q9UJX2,Q9UJX3,Q9UJX4	4
Mitotic prophase	0.292316814865487	0.7775732180675858	0.4368206548073641	1.0	0.6798202243690765	59	Q8NFH3,O95067,Q8NFH5,P53350,P50402,P52948,Q12769,Q9BTX1,O75694,Q9Y2U8,P61019,P20700,Q8N1F7,Q7Z3B4,P30154,Q9H0U4,Q8WUM0,Q8NFH4,P57740,P42167,Q01105,P42166,P62820,Q9BW27,P02545,Q86Y07,Q5SRE5,Q99567,P30153,Q96EE3	30
Thrombin signalling through proteinase activated receptors pars	0.5014891539593413	0.7735974654621978	0.4391688713890032	1.0	0.6827211782342828	6	P29992	1
Negative feedback regulation of mapk pathway	0.4044576523031225	0.7684235603092374	0.4422355875712789	1.0	0.6844700093035162	3	P28482,P27361	2
Role of lat2 ntal lab on calcium mobilization	0.3707664884135543	0.764807831778898	0.4443859834937878	1.0	0.6864714961173546	2	P62993	1
Wnt ligand biogenesis and trafficking	0.4986843380195602	0.7603261511577974	0.447059653876547	1.0	0.6877897962732851	6	Q5T9L3	1
Interleukin 4 and interleukin 13 signaling	0.4197725069885618	0.7599118720427019	0.4473072646685123	1.0	0.6877897962732851	12	P09601,P08670	2
Transcriptional regulation by ventx	0.4110658028874399	0.7563114608053029	0.4494624782746552	1.0	0.6901924003436815	14	Q96DE5,Q9UJX2,Q9UJX3,Q9UJX4	4
Regulation of kit signaling	0.3680926916221105	0.7487697130785523	0.4539960174130768	1.0	0.6942889203388702	2	P62993	1
Regulation of glucokinase by glucokinase regulatory protein	0.3365651652080101	0.730498564660418	0.4650854900131231	1.0	0.7051296138908641	27	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	15
Sumoylation of sumoylation proteins	0.3365651652080101	0.730498564660418	0.4650854900131231	1.0	0.7051296138908641	27	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	15
Fatty acyl coa biosynthesis	0.3902543144499748	0.7182578280547056	0.4725983277081074	1.0	0.7126883872389641	17	Q53GQ0,Q9P035,P50897,Q9UMR5,Q6Y1H2	5
Disorders of transmembrane transporters	0.2688156233849392	0.7122885152788092	0.4762861343490092	1.0	0.7167165949115294	77	Q8NFH3,Q99436,P28074,Q8NFH5,P61289,P52948,Q9NRG9,Q12769,P25787,P35613,Q9BTX1,O75694,P28070,P28072,Q8N1F7,O00231,Q7Z3B4,O75477,P49721,Q8WUM0,Q8NFH4,P57740,Q14997,Q9GZP9,P11166,Q9BW27,P08195,P20618,P53985,Q5SRE5,Q9BUN8,Q9UBV2,P60900,Q9UL46,Q99567,P49720,Q96EE3,Q13438,P62191	39
Calnexin calreticulin cycle	0.4361824177745413	0.6981989580513221	0.485052778012859	1.0	0.7238722395581625	10	Q9GZP9,Q9UBV2,P27824	3
Potential therapeutics for sars	0.3112799000823097	0.6823364890638695	0.4950262051661691	1.0	0.7362731532534794	39	P62942,P21964,P05023,Q99720,P49354	5
Phase i functionalization of compounds	0.3945296567591909	0.679358068139229	0.4969110117539745	1.0	0.7381847727332571	15	O43169,Q16850	2
Signaling by insulin receptor	0.3764067364493821	0.6617815636044675	0.5081112232857192	1.0	0.7481334076305756	18	P31751,Q9Y487,Q93050,Q15904	4
Cargo trafficking to the periciliary membrane	0.3573056717752276	0.6614773361555625	0.5083062443333981	1.0	0.7481334076305756	21	O43924,A6NIH7	2
Sumoylation of ubiquitinylation proteins	0.322096343743066	0.6572724423708687	0.511005752625715	1.0	0.750539699169019	29	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8N1F7,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,O75925,Q96EE3,Q9BW27	16
Signal amplification	0.4496769833033054	0.6481325106379423	0.5168992482395323	1.0	0.7576174012658425	8	P29992,Q16539	2
Rhoh gtpase cycle	0.3393063187334216	0.6351730931825681	0.5253155298106498	1.0	0.7643910186099238	23	Q6IAA8,P02786,Q13153,Q99707,Q8TAA9,Q9Y6M7,Q9BXS4	7
Cilium assembly	0.2759581333350338	0.6337784990675748	0.5262253868849176	1.0	0.764925562379107	64	O43924,Q9H6D7,Q13561,Q10713,O94927,O75935,A6NIH7,O95684,P41208,O43805,A0AVF1,Q92973	12
G1 s specific transcription	0.420007609747188	0.6101863184980809	0.541738391736716	1.0	0.7787268665130956	10	P00374	1
Signaling by erbb2 ecd mutants	0.403388822829949	0.5878968260854761	0.5566015469720087	1.0	0.7919356016453404	4	P62993,Q16543,P07900	3
Signaling by erbb2 in cancer	0.403388822829949	0.5878968260854761	0.5566015469720087	1.0	0.7919356016453404	4	P62993,Q16543,P07900	3
Prevention of phagosomal lysosomal fusion	0.4024970273483795	0.583451658042187	0.5595892910713356	1.0	0.7937836020227195	4	P20339,Q9H267,O14964	3
Egr2 and sox10 mediated initiation of schwann cell myelination	0.4359595503212821	0.5801412358141773	0.5618193779305898	1.0	0.796146053147871	8	Q9NR77	1
Defects in cobalamin b12 metabolism	0.399862725528507	0.5703656637120567	0.5684297130321971	1.0	0.8014858953753979	4	Q9NPF0	1
Sars cov 2 infection	0.3189997721949967	0.5450292508205249	0.5857333999965628	1.0	0.8136618875041682	26	P17844,P04843,Q96FZ7,Q13724,O43633,P48729,P46977,Q16706,P27824,Q10472	10
Collagen formation	0.3793964768918278	0.5379195549518918	0.5906325874325016	1.0	0.81566302475987	13	O75718,P13674,Q32P28,O15460	4
Traf3 dependent irf activation pathway	0.3309566250742807	0.5332881104030395	0.5938341567273233	1.0	0.8176817978374276	2	Q7Z434	1
Regulation of innate immune responses to cytosolic dna	0.3903091557669373	0.5235038137260957	0.6006236977718171	1.0	0.8242669365357245	4	Q13049,Q9UJV9,P19474	3
Antigen activates b cell receptor bcr leading to generation of second messengers	0.3279857397504543	0.5168009383262642	0.6052951249620004	1.0	0.8294131449916624	2	P62993	1
Copii mediated vesicle transport	0.3054766662923265	0.5130550053271765	0.607912844484543	1.0	0.8312893478158743	30	Q15363,Q12907,P49755,Q13190,Q9H0U4,Q9HCU5,O15027,Q9Y296,P49257,O75396,P62820	11
Josephin domain dubs	0.3560178306092144	0.5068708128866881	0.6122454661047856	1.0	0.8340735335340557	3	P54725,P55072	2
Diseases associated with glycosylation precursor biosynthesis	0.4247927597911237	0.4840068723202204	0.6283809918750625	1.0	0.849489164471561	7	P10619	1
Golgi cisternae pericentriolar stack reorganization	0.3842581863523582	0.4808302988533456	0.6306371142324712	1.0	0.8515967802553452	11	O95067,P53350,P06493,Q9H0U4,P61019,P62820	6
Sumoylation of rna binding proteins	0.2965310699644196	0.4773864293674291	0.6330869758592754	1.0	0.8526090753302092	33	Q8NFH3,Q9BTX1,Q7Z3B4,P61978,Q8NFH5,O75694,P07910,Q5SRE5,P52948,Q8WUM0,Q8IXK0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	18
Nuclear pore complex npc disassembly	0.2999202068312519	0.470345551869057	0.6381081578591203	1.0	0.8526090753302092	31	Q8NFH3,Q9BTX1,Q7Z3B4,O95067,Q8NFH5,O75694,Q5SRE5,P52948,P06493,Q8WUM0,Q8NFH4,P57740,Q99567,Q9NRG9,Q12769,Q8N1F7,Q96EE3,Q9BW27	18
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.3636056503661916	0.4643780806882821	0.6423768914651671	1.0	0.8528732739791767	14	Q12834,Q9UJX3,Q96DE5,Q9UJX2,Q9UJX4	5
Apc cdc20 mediated degradation of nek2a	0.3636056503661916	0.4643780806882821	0.6423768914651671	1.0	0.8528732739791767	14	Q12834,Q9UJX3,Q96DE5,Q9UJX2,Q9UJX4	5
Signaling by erbb4	0.418564778993135	0.4560404780254336	0.6483608708670938	1.0	0.8559820486166688	7	P46934	1
Interactions of vpr with host cellular proteins	0.2928859753422357	0.4520640436837957	0.6512228457935167	1.0	0.8576049085156757	34	Q8NFH3,Q9BTX1,Q7Z3B4,P05141,Q8NFH5,O75694,Q9BW27,Q5SRE5,P52948,Q8WUM0,P12235,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,P12236	18
Peroxisomal protein import	0.3286687357487327	0.4499618375790605	0.652737957975515	1.0	0.8585452618894368	21	Q13011,Q9BY49,P39210,O75381,O00116,Q15067,O15254	7
Sars cov infections	0.2606063127392697	0.4439749379221542	0.65706070365396	1.0	0.859000105721919	65	P62942,P21964,P05023,P46977,Q99720,P49354,Q10472	7
Neurotransmitter receptors and postsynaptic signal transmission	0.2926555600004089	0.4414437672614001	0.6588917627762159	1.0	0.8594240384037598	33	P54619,Q14168,P51812,P63010,Q12959,P63218,P52292,P07196,Q14012,Q9BVA1	10
Transmission across chemical synapses	0.2865367930214941	0.4343068768032071	0.6640656107705771	1.0	0.8643517656973725	40	P54619,Q14168,P51812,P21964,P63010,Q12959,P63218,P52292,O75915,P07196,Q14012,Q9BVA1	12
Glycogen breakdown glycogenolysis	0.413171762065965	0.4321777528999458	0.6656122272437033	1.0	0.8643517656973725	7	P46020	1
Dap12 signaling	0.3709869203329261	0.4320091482636685	0.6657347642179763	1.0	0.8643517656973725	4	P63000,P62993,P19174	3
Pre notch expression and processing	0.3738238426202956	0.4257962251888378	0.6702563377834476	1.0	0.8646490725294247	11	Q15363,P16615	2
Miro gtpase cycle	0.3957639611336461	0.4226998927003859	0.6725142338933838	1.0	0.8663345228104173	5	Q8IWA4,O95140,Q8IXI1	3
Signaling by flt3 fusion proteins	0.3922093369015842	0.4072945673249049	0.683791652406853	1.0	0.8733208604109264	5	Q14789,Q15643,P62993,Q01082	4
Small interfering rna sirna biogenesis	0.36504652851005	0.4048977833390352	0.6855526478265037	1.0	0.8746884601288997	4	O75569	1
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol	0.3352154531946528	0.4033252331614623	0.6867089812116223	1.0	0.8746884601288997	3	O14975,P51659	2
Rhof gtpase cycle	0.3264649291163989	0.3951815306133003	0.6927089221653373	1.0	0.8799275497775906	20	Q9Y4F1,P20700,P42167,Q9Y6M7,Q8TAA9,P42166,O60879	7
Abortive elongation of hiv 1 transcript in the absence of tat	0.34721643891989	0.3884909387545699	0.6976527583752676	1.0	0.8804265601457405	15	Q8IXH7	1
Cellular response to chemical stress	0.2470017283850028	0.3878790836790854	0.6981055175143824	1.0	0.8804265601457405	77	P00403,Q9P0S2,P09601,P49721,P13073,P28070,P30519,P28072,O43819	9
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.343407076488592	0.38699157847513	0.6987624425668089	1.0	0.8804265601457405	16	P09601,Q96RD7,P05067	3
Traf6 mediated irf7 activation	0.3310549777117405	0.3834831421662604	0.7013615672833466	1.0	0.8804265601457405	3	Q7Z434,Q12933	2
G alpha s signalling events	0.4134272669078677	0.381767579135049	0.7026337686814068	1.0	0.8806343234140299	6	Q9Y3E5	1
Fgfr2 alternative splicing	0.3353907964868606	0.3623383732930789	0.7170991858371005	1.0	0.890150756332122	17	P31943,P52272,P35269,P52597,P30876,P19388,P31483	7
Synthesis of bile acids and bile salts	0.3954331538064906	0.3562706027062152	0.7216379225102703	1.0	0.890150756332122	7	P51659,Q9BZF3,Q9H4L5	3
Bile acid and bile salt metabolism	0.3954331538064906	0.3562706027062152	0.7216379225102703	1.0	0.890150756332122	7	P51659,Q9BZF3,Q9H4L5	3
Signaling by retinoic acid	0.3470437547640338	0.3554687067995983	0.7222384844754848	1.0	0.890150756332122	13	P09622,P11177,Q8NBN7,Q15118,P50416	5
Syndecan interactions	0.3794231341064626	0.3533238451700806	0.7238456710183381	1.0	0.890150756332122	5	P17301,P05556,Q9Y296,O14936	4
Nef mediated downregulation of mhc class i complex cell surface expression	0.3791171066190928	0.352061335804713	0.7247922639371087	1.0	0.8902065262642189	5	P04439	1
Synthesis of pips at the late endosome membrane	0.2961972667855121	0.3503439971443868	0.7260805499789296	1.0	0.8909884045274507	2	O00443	1
Export of viral ribonucleoproteins from nucleus	0.2871792763124822	0.3488943333208847	0.7271686395526558	1.0	0.8909884045274507	29	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	15
Sumoylation of transcription factors	0.3483947681331647	0.3318792194319858	0.7399804624002821	1.0	0.8958740570306358	4	O75925,Q12888,P04637	3
Energy dependent regulation of mtor by lkb1 ampk	0.3797177056436736	0.3219617810068884	0.7474816484286242	1.0	0.9007986245816768	8	P54619,Q6IAA8,Q15382	3
Neutrophil degranulation	0.2342650826836744	0.3189707173089838	0.7497487180466886	1.0	0.9007986245816768	176	Q4KMQ2,P16278,Q8NHP6,Q9H7Z7,O75787,Q08722,P30519,Q9NQX7,P11279,O00560,P61026,P06280,O43681,Q8N2G8,O15121,P10619,Q93050,O00231,O00264,Q07065,Q96CS3,Q9BTY2,P13473,P10253,Q92820,P61916,P10321,Q8WVQ1,Q8NF37,P04439,P17900,Q13510,P07602,P09960,P04066,O95721,Q92542,O00584,P20618,Q6IAA8,P42785,Q9NZJ7,Q969Q5,Q5T9A4,Q16539	45
Dscam interactions	0.3448310413351083	0.3168750935329093	0.7513383813742984	1.0	0.9007986245816768	4	Q16539	1
Sulfur amino acid metabolism	0.3612774388467747	0.3151620677040723	0.7526386046015636	1.0	0.9007986245816768	10	Q9UBX3	1
Plasma lipoprotein clearance	0.3334830768171958	0.3112761275604032	0.7555907138847411	1.0	0.9007986245816768	15	P35610,Q8WTV0,P61916	3
Constitutive signaling by ligand responsive egfr cancer variants	0.3684210526315875	0.3088599323097336	0.7574280769524984	1.0	0.9007986245816768	5	P19174,P62993,Q16543,P07900	4
Constitutive signaling by egfrviii	0.3684210526315875	0.3088599323097336	0.7574280769524984	1.0	0.9007986245816768	5	P19174,P62993,Q16543,P07900	4
Signaling by egfr in cancer	0.3684210526315875	0.3088599323097336	0.7574280769524984	1.0	0.9007986245816768	5	P19174,P62993,Q16543,P07900	4
Platelet activation signaling and aggregation	0.2564787765807223	0.3076720471313763	0.7583318917577662	1.0	0.9007986245816768	57	Q8NBM8,Q9NUQ9,P13473,Q9NZJ7,Q08380,O43852,P29992,Q92520,Q6UXV4,Q8NCG7,O94919,P07602,Q8NBX0,Q9Y6I9,Q16539,P05067	16
Pyruvate metabolism	0.3289746625797822	0.303768903249088	0.7613039594982569	1.0	0.90280789141509	16	P21796,P53985,Q15118,O95563,P11177,P48163,P35613	7
Viral messenger rna synthesis	0.2742239418272031	0.2989404146524908	0.7649855098240419	1.0	0.9064114023965538	36	Q8NFH3,Q9BTX1,Q7Z3B4,P35269,Q8NFH5,O75694,Q5SRE5,P30876,P52948,Q8WUM0,P19388,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	18
Sars cov 1 infection	0.3288003390354735	0.285944278379673	0.7749207996941578	1.0	0.9143416967102616	15	Q10472,Q13724	2
Intra golgi and retrograde golgi to er traffic	0.2396075818931633	0.2829383828093262	0.7772240709932867	1.0	0.9149445697945084	105	Q15363,P24390,Q7Z6M1,Q13561,P40616,P49755,Q9BVA1,Q12981,P51151,O43493,P20645,Q8TD16,O75935,Q9P2W9,O60499,O95249,Q96MW5,Q6NUQ1,O00461,Q14964,Q10472,Q5VZE5,Q9UJW0,Q9H0U4,Q9BVK6,Q9H0H5,Q8TBA6,O95721,P62820,Q13190,O60476,Q16706,P48444,O75396	34
Ion homeostasis	0.3534419337076705	0.2799272464307235	0.779533322910791	1.0	0.9159516544201796	10	P16615	1
Cardiac conduction	0.3534419337076705	0.2799272464307235	0.779533322910791	1.0	0.9159516544201796	10	P16615	1
Cdc42 gtpase cycle	0.2690352003415239	0.2616138267429553	0.7936191829959764	1.0	0.9235593585392902	37	Q6IAA8,P02786,Q13153,Q9UQB8,Q9Y4F1,Q9H0H5,Q86YQ8,P42167,Q8TAA9,Q14739,P42166	11
Interferon gamma signaling	0.3253391883930059	0.2546868030797239	0.7989650098211813	1.0	0.9242328464939356	14	P10321,P18031,P04439,P13591,O75925,P01889	6
Fceri mediated ca 2 mobilization	0.3281807372175873	0.2500304720268369	0.8025637836014512	1.0	0.9265710864249932	4	P19174,P62993,Q08209	3
Regulation of plk1 activity at g2 m transition	0.2669879848424836	0.2450367039951881	0.8064280118097436	1.0	0.9289734449769104	39	Q9H6D7,Q15154,Q13561,O95067,P07437,O14974,O75935,O94927,Q68CZ6,Q13616,O95684,P41208,O43805,P30153	14
Binding and uptake of ligands by scavenger receptors	0.3641508280352684	0.233939350695887	0.8150320632594221	1.0	0.9358267175861442	7	Q8WTV0	1
Ripk1 mediated regulated necrosis	0.324342379767741	0.2323494578801406	0.816266601484835	1.0	0.9361943867156742	12	P41440,Q16543,Q14254,O75955,O00560	5
Dap12 interactions	0.3718925550554831	0.2264679876035981	0.8208374546629715	1.0	0.9386705685926924	6	P01889,P10321	2
Diseases of mitotic cell cycle	0.3161039840740234	0.2201439286025577	0.8257590638009273	1.0	0.9420066989962036	15	Q96DE5,Q9UJX2,Q9UJX3	3
Ns1 mediated effects on host pathways	0.267113396334627	0.2180154110560727	0.8274171039414369	1.0	0.9431350982679272	33	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,P52292,Q86U42,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	17
Tysnd1 cleaves peroxisomal proteins	0.3689344966041065	0.2164640327155283	0.8286260582657181	1.0	0.943586566703603	6	O00116,Q15067,Q2T9J0	3
Formation of the early elongation complex	0.3007236041841717	0.2065381553148092	0.8363705635415728	1.0	0.9479762818276668	19	Q8IXH7	1
Transport to the golgi and subsequent modification	0.238238958857934	0.2033375065902658	0.8388712417959872	1.0	0.949284471053244	83	Q15363,P24390,Q13561,O75396,P49755,O75935,O95249,O15027,Q96MW5,Q9Y296,P49257,Q12893,Q9UJW0,Q9H0U4,Q9HCU5,Q9BVK6,P04066,P62820,Q96PC5,Q12907,Q13190,O60476,Q16706,P48444,Q9BVA1	25
Glutamate neurotransmitter release cycle	0.288261515601785	0.2008108926865123	0.8408464452929754	1.0	0.9492865436241016	3	O75915,Q13136	2
Ephrin signaling	0.3362776077133879	0.1912429834825831	0.8483352290862416	1.0	0.952200806798327	5	O00560	1
Alpha linolenic omega3 and linoleic omega6 acid metabolism	0.3603544315990332	0.1883415061983114	0.8506089502687426	1.0	0.952200806798327	6	Q15067	1
Sensory perception	0.2738491994390095	0.1781845944083545	0.8585780079989407	1.0	0.9592670295392284	25	P49354,Q6NUM9	2
Rhoq gtpase cycle	0.2807493632686348	0.1676236291885004	0.8668793808146225	1.0	0.9637082324104512	22	Q6IAA8,Q15758,P02786,Q13153,Q8TAA9,Q9Y6M7	6
Senescence associated secretory phenotype sasp	0.2804536374658775	0.165841634595812	0.8682815801083335	1.0	0.9637082324104512	22	Q96DE5,Q9UJX2,P51812,Q9UJX3	4
Transcriptional regulation by e2f6	0.3428412071362168	0.1608008962765579	0.8722502192969219	1.0	0.9661216097475726	7	Q9UBK9,P31350	2
Pp2a mediated dephosphorylation of key metabolic factors	0.275331912977438	0.1547106794168477	0.8770494104133677	1.0	0.9696223175074058	3	P30154	1
Epha mediated growth cone collapse	0.3406724189229433	0.1538784214528589	0.8777055986282158	1.0	0.9696223175074058	7	P35580,O75116,P35579,Q15375,P60660,Q7Z406	6
Cohesin loading onto chromatin	0.3223434759514582	0.1533002684605992	0.8781614889765654	1.0	0.9696223175074058	10	Q7Z5K2	1
Plasma lipoprotein assembly remodeling and clearance	0.2968872104456634	0.1509554663585973	0.8800108459309011	1.0	0.9701448731529088	17	Q8WTV0,P61916,Q6PIU2,P35610,P07237	5
Piwi interacting rna pirna biogenesis	0.3136741460448035	0.1491471280866133	0.8814375389043316	1.0	0.9709585389493028	11	Q8N2A8,Q9Y2W6,P19388	3
Establishment of sister chromatid cohesion	0.3318452380952401	0.1422100406299604	0.8869141011211334	1.0	0.9754296100999748	8	O60216,Q14683,Q9UQE7,Q8N3U4,Q8WVM7,Q29RF7,Q7Z5K2	7
Regulation of pyruvate dehydrogenase pdh complex	0.3315888595459777	0.1413774523253909	0.8875717657860054	1.0	0.9754296100999748	8	Q15118,P11177	2
Death receptor signalling	0.2604978323046944	0.1280394135453992	0.898117782225963	1.0	0.9826371947185648	28	Q9NQC3,Q8TCT8	2
G beta gamma signalling through cdc42	0.2914507602487435	0.1244408881269866	0.9009662008858444	1.0	0.9840142085585132	4	P63218	1
Postmitotic nuclear pore complex npc reformation	0.2667088741797999	0.1213826338558914	0.9033879713430432	1.0	0.985133054596822	24	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,Q8WUM0,Q8NFH4,P57740,Q12769,Q8N1F7,Q96EE3,Q9BW27,Q92973	14
M phase	0.2231013077154541	0.1149119020631141	0.9085149511093368	1.0	0.9868877288981238	203	Q9H6D7,Q13561,Q8NFH5,Q86XL3,P61289,P50402,Q15005,O95684,Q9UJX2,Q7Z5K2,Q9BTX1,Q9UJX3,Q8IXJ6,Q9BS16,O75935,Q96DE5,Q9UJX4,P28070,Q9Y6X3,P28072,Q8N1F7,O00231,Q8NBT2,Q9BZD4,P49721,Q68CZ6,Q8NFH4,P41208,P42167,Q01105,P42166,P62820,Q92973,O43805,P02545,Q86Y07,O94927,Q9BSJ2,Q14739	39
Platelet homeostasis	0.3164116852113384	0.1106085509033625	0.9119267664576788	1.0	0.9868877288981238	9	P20020,Q16539,P16615,P63218	4
Lysosome vesicle biogenesis	0.2919168545593035	0.1082016866690245	0.9138357070444436	1.0	0.9870334973473528	15	Q10567,P51809,P15586,P50570,P05067	5
Heme biosynthesis	0.3068434669223603	0.1023833740230823	0.9184523799267794	1.0	0.9908323302959136	5	P22830,P36551	2
Chl1 interactions	0.2803210463733593	0.0930650577186157	0.9258518768246118	1.0	0.9950084956727916	4	P17301,P05556,O14786	3
P75 ntr receptor mediated signalling	0.2765206062250585	0.0812235631002556	0.9352641607800928	1.0	1.0	19	Q9NQC3	1
Rho gtpases activate nadph oxidases	0.2964614927148469	0.0758232005162264	0.9395597579125434	1.0	1.0	5	Q16539,P63000,P28482,P27361	4
Translation of replicase and assembly of the replication transcription complex	0.2964614927148457	0.0758232005162231	0.939559757912546	1.0	1.0	5	O43633,Q8WUX9,Q9UQN3,Q96FZ7	4
Transport of the slbp dependant mature mrna	0.2502090262975456	0.0703289765367401	0.943931819660876	1.0	1.0	31	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	15
Cyclin a b1 b2 associated events during g2 m transition	0.2844115353397795	0.0700213041859148	0.9441767029653948	1.0	1.0	12	P30153,Q99640,O95067,P30154	4
Nuclear import of rev protein	0.2500149125832481	0.0690168425924539	0.9449762130163746	1.0	1.0	31	Q8NFH3,Q9BTX1,Q7Z3B4,Q8NFH5,O75694,Q5SRE5,P52948,Q8WUM0,Q8NFH4,P57740,Q99567,Q12769,Q8N1F7,Q96EE3,Q9BW27	15
Hcmv late events	0.2455757755634317	0.0682111152968483	0.9456175788540466	1.0	1.0	37	Q8NFH3,P61978,Q8NFH5,P52948,Q9NRG9,Q12769,Q9BTX1,Q96FZ7,O43633,O75694,Q8N1F7,Q7Z3B4,Q8WUM0,Q8NFH4,P57740,Q9H9H4,Q9BW27,Q5SRE5,Q99567,Q96EE3	20
Trans golgi network vesicle budding	0.2457989018240836	0.0676231919695902	0.9460855931333187	1.0	1.0	39	Q10567,P02786,Q92572,O75976,Q9Y5X1,P51809,O00443,P55327,P50570,P15586,O43493,P20645,P05067	13
Transcriptional regulation of white adipocyte differentiation	0.2797522120894326	0.0594801152950755	0.9525697031278156	1.0	1.0	15	O75448,O60244,Q9NPJ6	3
Abc transporter disorders	0.242789931543865	0.0500976173082947	0.9600445984684188	1.0	1.0	44	P49721,P61289,Q9BUN8,P28070,P28072,Q9GZP9,Q9UBV2,O00231	8
Defective cftr causes cystic fibrosis	0.242789931543865	0.0500976173082947	0.9600445984684188	1.0	1.0	44	P49721,P61289,Q9BUN8,P28070,P28072,Q9GZP9,Q9UBV2,O00231	8
Association of tric cct with target proteins during biosynthesis	0.2710064942929009	0.0451365799987804	0.9639984444996864	1.0	1.0	18	P04062	1
Rna polymerase iii transcription initiation from type 1 promoter	0.2797140303842778	0.0345504530835264	0.9724382105982794	1.0	1.0	11	O14802,Q9UKN8,Q8WUA4,Q9BUI4,P62875,P19388,Q9Y5Q8,Q9Y5Q9,Q12789,P52434	10
Rnd2 gtpase cycle	0.2711303931010684	0.0282943425853835	0.9774273927579282	1.0	1.0	15	Q07065,P38159,P51648,Q8TAA9	4
E3 ubiquitin ligases ubiquitinate target proteins	0.2711012024068908	0.0281935993184478	0.97750774220054	1.0	1.0	15	Q14527,Q9BUN8,P04439,O75381	4
Activation of the pre replicative complex	0.2500510887667338	0.0228719758687583	0.981752394563165	1.0	1.0	23	O75419,Q9Y619,P33993,Q9NRF9,Q14566,P56282	6
Recycling of eif2 gdp	0.2880544327457342	0.0185465400597064	0.9852028503410696	1.0	1.0	7	Q9NR50	1
Mrna decay by 3 to 5 exoribonuclease	0.2684988917156187	0.0180107821181489	0.9856302519204372	1.0	1.0	14	Q969T7,Q6PGP7,Q96C86	3
Ub specific processing proteases	0.2196873864629809	0.0172282130702283	0.9862545547517104	1.0	1.0	78	P21796,P49721,P45880,P28070,Q9Y277	5
Myogenesis	0.2908982748363982	0.0155301249976028	0.987609251115755	1.0	1.0	6	Q16539,P19022,P35221,P35222,O60271	5
Retrograde transport at the trans golgi network	0.2509712716518976	0.0087987715539036	0.992979686606775	1.0	1.0	22	Q7Z6M1,P40616,Q5VZE5,O60499,Q96MW5,P51151,O43493	7
Antigen processing cross presentation	0.2296520872034648	0.0062693172230309	0.9949978413487456	1.0	1.0	54	P20618,P10321,Q03518,P49721,P61289,P04439,P28070,Q03519,P28072,Q9UIQ6,O00231	11
Glycogen metabolism	0.2731793965325913	0.0050881610977625	0.995940252334619	1.0	1.0	10	P46020	1