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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:9ac140818f7f18dbff345c5d8ed7e962d8f50aba7eff23b3b0172014d7608c9d
+size 62733

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.4
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C163/C163_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9637495422922008	2.0555217763672484	0.0398286345436331	0.8930498843569742	0.4892356070245213	3	Q9H3G5,P10619	2
+Histidine acid phosphatase active site [IPR033379]	0.8151537335285564	0.8912008299782259	0.3728214392381312	0.9999999999928136	0.8543824649207176	2	P11117	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.3510248901903279	0.0330122524640235	0.973664816914256	1.0	0.973925069175843	2	P18031	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.3466325036603207	0.0326858985933621	0.973925069175843	1.0	0.973925069175843	2	Q9NQ88	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CASP3", "CASP6", "CASP7", "CASP8", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACP2", "CPVL", "CTSA", "PTPN1", "TIGAR"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c929420bc9f7147dd807a474a87dc29c91581b10ef69df72ce436274891d03c6
+size 61128

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.032258064516129
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C163/C163_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.4871478385553805	0.5436225621761317	0.5867012305126968	0.9999999999987288	1.0	5	P22695	1
+Beta tubulin, autoregulation binding site [IPR013838]	0.4618768328445751	0.5165420684692927	0.6054758649334977	0.9999999999996992	1.0	6	Q13885,Q9BVA1,P04350,P68371,P07437	5
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.4418008784773131	0.0538604443082465	0.9570463517646042	1.0	1.0	2	O75600	1
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.378477306002923	0.0360303285574895	0.9712581759566056	1.0	1.0	2	P34897	1
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.3491947291361644	0.0328719228341991	0.973776723023549	1.0	1.0	2	Q9H0C8	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Adrenodoxin, iron-sulphur binding site [IPR018298]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPNS1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FDX1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2", "VRK1"], "leading_proteins": ["GCAT", "ILKAP", "SHMT2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 protein, conserved site [IPR023409]", "1": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:c3a77ee6212c4799976b768500bd4ccba0bedefc1242f0dee182ebfc44d27643
+size 62576

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 264,
+    "title": "Average number of proteins per term",
+    "value": 2.496212121212121
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C163/C163_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.850549450549451	1.948693942522254	0.0513319856191736	0.9999990918363536	0.8469098711152967	4	O15400,Q13190,Q9P2W9	3
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7339680901988976	1.7015521845901176	0.0888393474417366	0.9999999999784688	0.8469098711152967	8	P49721,P20618,P28072	3
+Tetraspanin, conserved site [IPR018503]	0.9923133235724744	1.5612647271059332	0.1184613024425216	0.9999999999999964	0.8469098711152967	2	O60637	1
+Haem oxygenase conserved site [IPR018207]	0.9901171303074676	1.5528353634956702	0.1204624718645903	0.999999999999998	0.8469098711152967	2	P30519	1
+Sterol reductase, conserved site [IPR018083]	0.9198389458272356	1.2833943793427391	0.1993539420557843	1.0	0.8488619468181786	2	Q14739	1
+14-3-3 protein, conserved site [IPR023409]	0.6209677419354843	1.2342912378220243	0.2170943997984613	1.0	0.855416739504385	6	P31946,P62258,P63104,Q04917,P27348	5
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8440702781844797	0.9974139100227531	0.3185636422587028	1.0	0.9151647649138884	2	Q9BTY2	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.8400439238653055	0.9824955143463616	0.3258557917435627	1.0	0.9151647649138884	2	P13473	1
+Guanylate kinase, conserved site [IPR020590]	0.5803356033533678	0.8355813322961071	0.4033904742465211	1.0	0.9681371381916506	4	Q14168,O14936	2
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.5714355023852891	0.7995940637013558	0.4239460279871105	1.0	0.9893404351342512	4	Q8NEB9	1
+Profilin conserved site [IPR027310]	0.7891654465592963	0.7979376607947497	0.424906667057275	1.0	0.9893404351342512	2	P07737	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.4941095235270478	0.6564531997963384	0.5115325702751399	1.0	1.0	6	P51648	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.7357247437774499	0.6152553995604291	0.5383860668396432	1.0	1.0	2	P50570	1
+Sugar transporter, conserved site [IPR005829]	0.7302342606149359	0.5973544298525242	0.5502707716570028	1.0	1.0	2	Q7L0J3	1
+Ribosomal protein S9, conserved site [IPR020574]	0.7177891654465676	0.5574875062935098	0.5771943928745233	1.0	1.0	2	P82933	1
+ABC transporter-like, conserved site [IPR017871]	0.4706606789864708	0.5362720336955965	0.5917705557675261	1.0	1.0	7	P08183,O75027,P28288	3
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.7097364568081985	0.5322464079765373	0.5945553446471574	1.0	1.0	2	Q13363	1
+Tubulin, conserved site [IPR017975]	0.4618768328445753	0.5165420684692937	0.605475864933497	1.0	1.0	6	Q13885,Q9BVA1,P04350,P68371,P07437	5
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.7024158125915086	0.5097014826120363	0.6102606141458531	1.0	1.0	2	P40939	1
+Histidine triad, conserved site [IPR019808]	0.6098096632503704	0.2647504341056056	0.7912017225008983	1.0	1.0	2	Q96C86	1
+Adenylate kinase, conserved site [IPR033690]	0.4208791208791227	0.2621153510373237	0.7932325120139545	1.0	1.0	4	P30085,P27144,P00568	3
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4558769681435372	0.2146451871038679	0.8300439607297061	1.0	1.0	3	P14625,P08238	2
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.5754026354319246	0.1963863375251911	0.8443077891227118	1.0	1.0	2	Q96FJ2	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.3910054284873692	0.1720790371145245	0.8633753928825076	1.0	1.0	11	Q06136,Q8NBN7,Q53GQ0	3
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.5516105417276737	0.1570878153320707	0.875175640316199	1.0	1.0	2	P36871	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.3615055355471857	0.1178067129187128	0.9062208104506424	1.0	1.0	4	Q9UBQ7,Q13363	2
+Thioredoxin, conserved site [IPR017937]	0.3584685340646922	0.0762234550983259	0.939241322500206	1.0	1.0	11	Q9H1E5,O95881	2
+Mrp, conserved site [IPR000808]	0.4432650073206486	0.0545344486683742	0.9565093633463372	1.0	1.0	2	Q9Y5Y2	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF8", "PHGDH", "PI4KB", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM35", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD3", "AK1", "AK4", "ALDH3A2", "CASK", "CMPK1", "CTBP1", "DCPS", "DNM2", "DYNLL2", "FUCA2", "GRHPR", "HADHA", "HMOX2", "HSD17B12", "HSP90AB1", "HSP90B1", "KDSR", "LAMP2", "LBR", "MPP2", "MRPS9", "NUBP2", "PFN1", "PGM1", "PIK3C3", "PSMB1", "PSMB2", "PSMB6", "RDH13", "STX18", "STX5", "STX7", "SV2A", "TMX4", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TXNDC12", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 domain [IPR023410]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "Tubulin/FtsZ, GTPase domain [IPR003008]", "3": "Rab-GTPase-TBC domain [IPR000195]", "4": "Exoribonuclease, phosphorolytic domain 1 [IPR001247]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:2ceeb007adb785602a3fdfb4eab5673188f45bfea73b9c44817949bb11aa8875
+size 95383

interpro_domain/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	6	2.2419797884745827	0.0249626786104277	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0234665278248752	0.0573151884822011	0.1105474823156849	0.0001450038876457	0.0001590313802548
+Target SNARE coiled-coil homology domain [IPR000727]	3	6	2.011715832490922	0.0442499006824004	3.5024271844660193	8.266990291262136	0.5942034778060385	0.4012381903331891	1.9023475359698396	2.183694577914796	1.0582363712887182	0.3038263160802639	0.089995351488155	1.0	1.0	0.1227655047468798	0.031065887399213

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 2335,
+    "title": "Average number of proteins per term",
+    "value": 2.091648822269807
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C163/C163_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,168 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8495950436501571	2.2419797884745827	0.0249626786104277	1.0	0.6997777870933648	6	Q8WUJ1,O43169,Q9UMX5,O15173	4
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8956043956043959	2.127399844044493	0.0333868751040196	1.0	0.6997777870933648	4	P05023,P16615,P20020	3
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9652142072500914	2.061102616000461	0.0392932513099215	1.0	0.6997777870933648	3	Q13432,A6NIH7	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.7953009934313562	2.011715832490922	0.0442499006824004	1.0	0.6997777870933648	6	Q9UEU0,O15400,Q13190	3
+Reticulon [IPR003388]	0.9194434273160016	1.8854488214938157	0.0593692678981987	1.0	0.6997777870933648	3	O95197,Q9NQC3	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.9157817649212744	1.8712891560973135	0.061305012765894	1.0	0.6997777870933648	3	P16615,P20020	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.9157817649212744	1.8712891560973135	0.061305012765894	1.0	0.6997777870933648	3	P16615,P20020	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9000366166239474	1.810233487827699	0.0702595865104487	1.0	0.6997777870933648	3	Q96G23,Q15629	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.6962810521131657	1.5550202047942516	0.1199412573870286	1.0	0.7116184545651172	7	Q99536	1
+GOLD domain [IPR009038]	0.6903024938180864	1.5495270371434533	0.1212550772197946	1.0	0.7116184545651172	6	Q15363	1
+EXPERA domain [IPR033118]	0.9809663250366032	1.5177075992642286	0.1290881274886621	1.0	0.7116184545651172	2	Q15125	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.819864678646473	1.4957761098293934	0.1347120089325175	1.0	0.7148921383123374	3	Q9NRF9	1
+Peptidase M16, C-terminal [IPR007863]	0.6771878520103266	1.469086563172601	0.1418093118052323	1.0	0.7245440379274319	7	Q10713,P22695,Q5JRX3	3
+Peptidase M16, N-terminal [IPR011765]	0.6771878520103266	1.469086563172601	0.1418093118052323	1.0	0.7245440379274319	7	Q10713,P22695,Q5JRX3	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7296135217969503	1.4547801986647666	0.1457301217431079	1.0	0.7245440379274319	4	O75027,P28288	2
+Fatty acid hydroxylase [IPR006694]	0.963030746705711	1.4488555380394998	0.1473779300614834	1.0	0.7245440379274319	2	O75845	1
+Peptidase M28 [IPR007484]	0.806298059318931	1.4421375820726978	0.1492635647709495	1.0	0.7245440379274319	3	P02786,Q7Z2K6	2
+MENTAL domain [IPR019498]	0.9505856515373377	1.4011062917279624	0.1611822904374009	1.0	0.731392713348177	2	O95772	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.680767202786488	1.3741331566851225	0.1694003475832002	1.0	0.7328891843028982	5	P09960	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.680767202786488	1.3741331566851225	0.1694003475832002	1.0	0.7328891843028982	5	P09960	1
+Band 7 domain [IPR001107]	0.6588403108021395	1.364938189785066	0.1722724778570841	1.0	0.7335580562752343	8	Q9UJZ1,P27105,O75955	3
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6571486926616799	1.3363477293126889	0.1814356427207695	1.0	0.7335724725207032	9	Q9Y680,Q96AY3,Q9NWM8	3
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9315519765739384	1.3281781520591711	0.1841192602121324	1.0	0.7335724725207032	2	Q8N2A8	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9297218155197696	1.3211750139982603	0.1864430154356182	1.0	0.7335724725207032	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9297218155197696	1.3211750139982603	0.1864430154356182	1.0	0.7335724725207032	2	Q9Y282	1
+Acyl transferase [IPR014043]	0.9253294289897528	1.3043756826441706	0.1921055221755563	1.0	0.7335724725207032	2	P49327	1
+ERAP1-like C-terminal domain [IPR024571]	0.7663367224858864	1.283899247490292	0.1991772105994409	1.0	0.7441260587995113	3	Q9UIQ6	1
+PA domain [IPR003137]	0.9187408491947302	1.2792007023399703	0.2008263886084891	1.0	0.7455160848979684	2	Q8TCT8	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.9070278184480282	1.2345290089496554	0.2170058439831579	1.0	0.7555558670106908	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.9070278184480282	1.2345290089496554	0.2170058439831579	1.0	0.7555558670106908	2	Q13505	1
+14-3-3 domain [IPR023410]	0.6209677419354843	1.2342912378220243	0.2170943997984613	1.0	0.7555558670106908	6	P31946,P62258,P63104,Q04917,P27348	5
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.752105455876968	1.227577369482563	0.2196056614416357	1.0	0.7555558670106908	3	P52888,Q99797	2
+Aminotransferase, class I/classII [IPR004839]	0.6146523714932188	1.1844267882982318	0.2362441612564541	1.0	0.7752806779388635	7	O15269	1
+Dynamin, GTPase domain [IPR001401]	0.7359941413401686	1.1639273098236431	0.2444534710589265	1.0	0.7873087654104738	3	P50570,O60313	2
+Major facilitator superfamily domain [IPR020846]	0.7305016477480777	1.142269046497348	0.2533422033948524	1.0	0.7993878430481228	3	P53985,Q7L0J3	2
+Complex 1 LYR protein domain [IPR008011]	0.8825036603221119	1.141452811922414	0.2536815382007105	1.0	0.7993878430481228	2	Q9NU23	1
+L27 domain [IPR004172]	0.7286708165507141	1.1350552787361643	0.2563521577650274	1.0	0.8009213975300677	3	Q14168,O14936	2
+L27 domain, C-terminal [IPR014775]	0.7286708165507141	1.1350552787361643	0.2563521577650274	1.0	0.8009213975300677	3	Q14168,O14936	2
+LEM domain [IPR003887]	0.596715711571054	1.1229522214357008	0.2614577868843595	1.0	0.8116442232718967	6	Q86XL3,P42167	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8660322108345528	1.0793962137931945	0.2804111380668095	1.0	0.8280895536184857	2	Q9NVI7	1
+START domain [IPR002913]	0.8579795021961986	1.0492246921529451	0.2940747167023865	1.0	0.841273078551235	2	Q14849	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8546852122986848	1.0369173696721328	0.29977436815224	1.0	0.8453899844835576	2	O00116	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8546852122986848	1.0369173696721328	0.29977436815224	1.0	0.8453899844835576	2	O00116	1
+Ion transporter-like, CBS domain [IPR044751]	0.8524890190336762	1.0287246073597234	0.3036091032459103	1.0	0.8465193264478194	2	Q8NE01	1
+CNNM, transmembrane domain [IPR002550]	0.8524890190336762	1.0287246073597234	0.3036091032459103	1.0	0.8465193264478194	2	Q8NE01	1
+Major sperm protein (MSP) domain [IPR000535]	0.700109849871842	1.0230032971631031	0.3063062868771395	1.0	0.8474151676712118	3	Q8NHP6,Q9P0L0	2
+Syntaxin, N-terminal domain [IPR006011]	0.8499267935578338	1.019179035799822	0.3081179774530445	1.0	0.8474151676712118	2	O15400	1
+Ribosomal protein L18e/L15P [IPR021131]	0.6979128524350054	1.0144303854322283	0.3103774315045426	1.0	0.8510361159674601	3	P46776,Q9P015	2
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8440702781844797	0.9974139100227531	0.3185636422587028	1.0	0.8589446936190197	2	Q9BTY2	1
+Exportin-2, central domain [IPR013713]	0.6718763398073735	0.9135268956155952	0.3609654948529073	1.0	0.871367775221317	3	P55060	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.6704023751380082	0.9078588966865834	0.3639527763521801	1.0	0.8716202387511186	3	Q32P28	1
+CBS domain [IPR000644]	0.5432653577275511	0.8777974178748734	0.3800536659934905	1.0	0.8812742316898127	6	P51790,Q8NE01	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5366037820357618	0.8277081036213325	0.4078358287169552	1.0	0.8958576294017784	7	Q8IWA4,Q9H223,P50570,O60313	4
+Dynamin, N-terminal [IPR045063]	0.5366037820357618	0.8277081036213325	0.4078358287169552	1.0	0.8958576294017784	7	Q8IWA4,Q9H223,P50570,O60313	4
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.5777405400292173	0.8250638150807392	0.4093353617141551	1.0	0.898306456393376	4	Q16134	1
+Immunoglobulin-like domain [IPR007110]	0.5385269657681784	0.8168424857147765	0.41401844919679	1.0	0.90264526505556	8	Q08722	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.7902635431918089	0.8018286536741203	0.4226520813110972	1.0	0.9071145067757964	2	Q8NEB9	1
+SCP2 sterol-binding domain [IPR003033]	0.642255584035152	0.8007906618048585	0.423252845971674	1.0	0.9071145067757964	3	P22307,Q6YN16	2
+Immunoglobulin subtype 2 [IPR003598]	0.5625919181744207	0.7640876899830902	0.4448149876384328	1.0	0.9141098579823383	4	Q13308,P35613	2
+Immunoglobulin subtype [IPR003599]	0.5625919181744207	0.7640876899830902	0.4448149876384328	1.0	0.9141098579823383	4	Q13308,P35613	2
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.5376081544256196	0.7519321750613448	0.4520918477743727	1.0	0.9141098579823383	5	Q8NEB9	1
+Legume-like lectin [IPR005052]	0.7737920937042526	0.7439839934602608	0.4568861588041475	1.0	0.914746816975208	2	Q12907	1
+Arfaptin homology (AH) domain [IPR010504]	0.7726939970717484	0.7401692240794983	0.4591973192144465	1.0	0.914868379151649	2	P53365	1
+LEM-like domain [IPR013146]	0.7690336749634026	0.7274930944329745	0.4669239441006854	1.0	0.9231730816893312	2	P42167	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.5238781819962273	0.6940799724442083	0.4876320575909942	1.0	0.929011040536232	5	Q14168,O14936	2
+Guanylate kinase-like domain [IPR008144]	0.5238781819962273	0.6940799724442083	0.4876320575909942	1.0	0.929011040536232	5	Q14168,O14936	2
+Sec23, C-terminal [IPR037550]	0.756954612005859	0.6861162610696023	0.4926397975243128	1.0	0.9309775435639084	2	Q15437	1
+Ubiquitin-like domain, USP-type [IPR028135]	0.7562225475841915	0.6836319868135489	0.4942075809562705	1.0	0.9309775435639084	2	Q9Y4E8	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.7415812591508145	0.6345494437703554	0.5257223098492507	1.0	0.9518412032168694	2	P49840	1
+Potentiating neddylation domain [IPR005176]	0.7393850658858067	0.627290541268692	0.5304688024913464	1.0	0.95188311980619	2	Q92564	1
+Tim44-like domain [IPR007379]	0.739019033674967	0.6260834600581984	0.5312602003426179	1.0	0.9520280643131334	2	O43615	1
+OCRE domain [IPR041591]	0.7371888726207914	0.6200599027750695	0.5352183496048228	1.0	0.953817500812266	2	P52756	1
+GTPase effector domain [IPR020850]	0.7357247437774499	0.6152553995604291	0.5383860668396432	1.0	0.953817500812266	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.7357247437774499	0.6152553995604291	0.5383860668396432	1.0	0.953817500812266	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.7357247437774499	0.6152553995604291	0.5383860668396432	1.0	0.953817500812266	2	P50570	1
+EB1, C-terminal [IPR004953]	0.7316983894582697	0.602109895869114	0.5471009877824113	1.0	0.9586144530361188	2	Q15555	1
+NOPS [IPR012975]	0.5862321493958258	0.5969670838059369	0.550529357217949	1.0	0.9586144530361188	3	P23246,Q15233	2
+Importin-beta, N-terminal domain [IPR001494]	0.509719371780378	0.5969568641069365	0.5505361805230986	1.0	0.9586144530361188	13	Q92973	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.5772776003610933	0.5659456418214303	0.5714307333054089	1.0	0.9586925298581196	3	Q8NF37	1
+Zinc finger, CHHC-type [IPR012996]	0.576711827169535	0.564003032774293	0.5727520681593476	1.0	0.9586925298581196	3	P31943,P55795	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.5713846883798351	0.5458177733436642	0.5851912047359886	1.0	0.9638227971587324	3	O75396	1
+Longin domain [IPR010908]	0.5713846883798351	0.5458177733436642	0.5851912047359886	1.0	0.9638227971587324	3	O75396	1
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.712298682284042	0.5402285035011826	0.5890394579134768	1.0	0.9685965733999776	2	Q13526	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4706606789864708	0.5362720336955965	0.5917705557675261	1.0	0.971849933080956	7	P08183,O75027,P28288	3
+HECT domain [IPR000569]	0.4646591000325346	0.5283817217106757	0.5972344212982421	1.0	0.971849933080956	6	Q05086,Q96J02	2
+CTP synthase, N-terminal [IPR017456]	0.7075402635431933	0.5254419238643181	0.5992760159039561	1.0	0.971849933080956	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.7075402635431933	0.5254419238643181	0.5992760159039561	1.0	0.971849933080956	2	Q9NRF8	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.4618768328445753	0.5165420684692937	0.605475864933497	1.0	0.971849933080956	6	Q13885,Q9BVA1,P04350,P68371,P07437	5
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.4618768328445753	0.5165420684692937	0.605475864933497	1.0	0.971849933080956	6	Q13885,Q9BVA1,P04350,P68371,P07437	5
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.7024158125915086	0.5097014826120363	0.6102606141458531	1.0	0.971849933080956	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.7024158125915086	0.5097014826120363	0.6102606141458531	1.0	0.971849933080956	2	P40939	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4919496920183394	0.4938049810141267	0.621443915060911	1.0	0.9758382929840128	4	Q9NVA2,Q15019	2
+CS domain [IPR007052]	0.4521653510995708	0.44176679698378	0.6586579676109257	1.0	0.9927260849866868	8	Q9HB71	1
+Peptidase M20, dimerisation domain [IPR011650]	0.6760614934114203	0.4319809510619236	0.665755258000118	1.0	0.9927260849866868	2	Q8IYS1	1
+Chromo domain subgroup [IPR017984]	0.5331380446722812	0.421563008866168	0.6733440112685196	1.0	0.9927260849866868	3	Q13185,P45973	2
+Chromo shadow domain [IPR008251]	0.5331380446722812	0.421563008866168	0.6733440112685196	1.0	0.9927260849866868	3	Q13185,P45973	2
+MIT domain [IPR007330]	0.6694729136164033	0.4134570407488676	0.6792717906525445	1.0	0.9927260849866868	2	Q8N0X7	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.5283778835591357	0.406968837794688	0.6840308758221081	1.0	0.9927260849866868	3	Q96EY1,O60884	2
+R3H domain [IPR001374]	0.5247268345916173	0.3959197048657087	0.6921642639916141	1.0	0.9927260849866868	3	O95453	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.6559297218155243	0.3766103191943774	0.7064632179091974	1.0	0.9927260849866868	2	Q9BSJ2	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.6559297218155243	0.3766103191943774	0.7064632179091974	1.0	0.9927260849866868	2	Q9BSJ2	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.6486090775988309	0.3574115280592297	0.7207837477993899	1.0	0.9927260849866868	2	O60506	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6475109809663274	0.3545765582673524	0.7229068403100969	1.0	0.9927260849866868	2	Q92945	1
+Rab-GTPase-TBC domain [IPR000195]	0.4186217008797657	0.3403890062388479	0.7335635966973897	1.0	0.9927260849866868	6	O60343,Q4KMP7,Q9Y3P9,Q8TC07,Q66K14	5
+Peptidase S9A, N-terminal domain [IPR023302]	0.6405563689604712	0.3368990176203791	0.7361930259006979	1.0	0.9927260849866868	2	Q4J6C6	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.6255490483162554	0.3004310714055593	0.7638483661291509	1.0	0.9927260849866868	2	P51116	1
+Zinc finger, CCHC-type [IPR001878]	0.4006527465061794	0.2583369731620329	0.7961468539665946	1.0	0.9927260849866868	7	Q9NUD5	1
+Jumonji, helical domain [IPR041070]	0.5929721815519818	0.229611240852819	0.8183938712972898	1.0	0.9927260849866868	2	Q9UPP1	1
+Mad3/Bub1 homology region 1 [IPR013212]	0.5900439238653058	0.2238274708749305	0.8228915535421024	1.0	0.9927260849866868	2	O43683	1
+PTB/PI domain [IPR006020]	0.4448919809593555	0.1910749658468593	0.8484668606344075	1.0	0.9927260849866868	3	O60343,Q9UKG1	2
+PABP, RNA recognition motif 2 [IPR045305]	0.5673499267935624	0.1823505088006823	0.8553076627954521	1.0	0.9927260849866868	2	Q13310	1
+SET domain [IPR001214]	0.390109890109892	0.1808032486683862	0.8565220130692048	1.0	0.9927260849866868	4	O96028,Q9H7B4,Q9BYW2	3
+Agenet-like domain [IPR008395]	0.437934822409374	0.1769762220789586	0.859527066781661	1.0	0.9927260849866868	3	P51114,P51116	2
+Fxr1, tudor domain [IPR041560]	0.437934822409374	0.1769762220789586	0.859527066781661	1.0	0.9927260849866868	3	P51114,P51116	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.437934822409374	0.1769762220789586	0.859527066781661	1.0	0.9927260849866868	3	P51114,P51116	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.437934822409374	0.1769762220789586	0.859527066781661	1.0	0.9927260849866868	3	P51114,P51116	2
+Thioesterase domain [IPR006683]	0.5611273792093733	0.172019974120363	0.8634218259888233	1.0	0.9927260849866868	2	O00154	1
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.3702346041055722	0.1679118870176227	0.8666525984178235	1.0	0.9927260849866868	6	Q15024,Q96B26,Q9NPD3,Q8TCS8,Q5RKV6	5
+CARG-binding factor, N-terminal [IPR012956]	0.554538799414356	0.1615708447251024	0.8716438181391772	1.0	0.9927260849866868	2	Q99729	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]	0.5516105417276737	0.1570878153320707	0.875175640316199	1.0	0.9927260849866868	2	P36871	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.5516105417276737	0.1570878153320707	0.875175640316199	1.0	0.9927260849866868	2	P36871	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.5516105417276737	0.1570878153320707	0.875175640316199	1.0	0.9927260849866868	2	P36871	1
+HDGF-related, PWWP domain [IPR035496]	0.4247528377883561	0.1520529856215294	0.8791451449775125	1.0	0.9927260849866868	3	Q7Z4V5,P51858	2
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.423565319244632	0.1499235585990255	0.8808249247106361	1.0	0.9927260849866868	3	Q9Y4E8	1
+Exoribonuclease, phosphorolytic domain 2 [IPR015847]	0.37009893733968	0.1439467341845385	0.8855425314062226	1.0	0.9927260849866868	5	Q15024,Q9NPD3,Q96B26,Q8TCS8	4
+Ribosomal protein L11, C-terminal [IPR020783]	0.5424597364568077	0.1437134498162438	0.8857267500385932	1.0	0.9927260849866868	2	Q9Y3B7	1
+Ribosomal protein L11, N-terminal [IPR020784]	0.5424597364568077	0.1437134498162438	0.8857267500385932	1.0	0.9927260849866868	2	Q9Y3B7	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.5395314787701394	0.1396356269714377	0.8889478901234504	1.0	0.9927260849866868	2	P32322	1
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.5395314787701394	0.1396356269714377	0.8889478901234504	1.0	0.9927260849866868	2	P32322	1
+Sec23/Sec24, helical domain [IPR006900]	0.3617905328055916	0.1225586400593158	0.9024566079040924	1.0	0.9927260849866868	5	Q15437,O95487	2
+Sec23/Sec24 beta-sandwich [IPR012990]	0.3617905328055916	0.1225586400593158	0.9024566079040924	1.0	0.9927260849866868	5	Q15437,O95487	2
+Sec23/Sec24, trunk domain [IPR006896]	0.3617905328055916	0.1225586400593158	0.9024566079040924	1.0	0.9927260849866868	5	Q15437,O95487	2
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.3617905328055916	0.1225586400593158	0.9024566079040924	1.0	0.9927260849866868	5	Q15437,O95487	2
+Glycosyltransferase 2-like [IPR001173]	0.5252562225475822	0.1211377253774756	0.9035819486567522	1.0	0.9927260849866868	2	Q10471	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.5252562225475822	0.1211377253774756	0.9035819486567522	1.0	0.9927260849866868	2	Q10471	1
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.3615055355471857	0.1178067129187128	0.9062208104506424	1.0	0.9927260849866868	4	Q9UBQ7,Q13363	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.3615055355471857	0.1178067129187128	0.9062208104506424	1.0	0.9927260849866868	4	Q9UBQ7,Q13363	2
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.3611721611721631	0.1171478044719784	0.9067429280108464	1.0	0.9927260849866868	4	P07900,P14625,P08238	3
+Macro domain [IPR002589]	0.5193997071742361	0.1142007952971579	0.9090786214789894	1.0	0.9927260849866868	2	Q9P0M6	1
+Core histone macro-H2A, macro domain [IPR035796]	0.5193997071742361	0.1142007952971579	0.9090786214789894	1.0	0.9927260849866868	2	Q9P0M6	1
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.3990700749960251	0.1102746131344507	0.912191590238363	1.0	0.9927260849866868	3	Q9Y4E8	1
+Survival motor neuron [IPR010304]	0.5051244509516833	0.0988298578441352	0.9212733614074458	1.0	0.9927260849866868	2	O75940	1
+Exonuclease, RNase T/DNA polymerase III [IPR013520]	0.5000000000000043	0.0938283885280244	0.9252454803748592	1.0	0.9927260849866868	2	Q9GZR2	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.3483516483516502	0.0931462407026615	0.9257873823222642	1.0	0.9927260849866868	4	Q16352,P08670,P07196	3
+Gelsolin-like domain [IPR007123]	0.3409136996581103	0.0807921850202363	0.9356072232035588	1.0	0.9927260849866868	6	Q15437,O95487	2
+Domain of unknown function DUF4749 [IPR031847]	0.4849926793557811	0.0806752836082108	0.9357001935536582	1.0	0.9927260849866868	2	Q96HC4	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.361772244599048	0.0651240821062629	0.9480752063815504	1.0	0.9927260849866868	3	Q10567,O00203	2
+COP9 signalosome complex subunit 7, helix I [IPR041481]	0.4597364568081939	0.0631780982004104	0.9496246850360106	1.0	0.9927260849866868	2	Q9H9Q2	1
+Zinc finger, TFIIB-type [IPR013137]	0.4516837481698496	0.0587019063123306	0.9531895409408212	1.0	0.9927260849866868	2	P29083	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.3511534236543391	0.055402185108471	0.9558180550484026	1.0	0.9927260849866868	3	P18031,Q99956	2
+Exportin-1/Importin-beta-like [IPR013598]	0.3241758241758259	0.0549599111126268	0.9561704017911324	1.0	0.9927260849866868	4	O43592,O14980,Q9HAV4	3
+Immunoglobulin I-set [IPR013098]	0.4322840409956027	0.0498250181920691	0.9602618298054304	1.0	0.9927260849866868	2	Q13308	1
+Adenylate kinase, active site lid domain [IPR007862]	0.4205710102488977	0.0456220175047014	0.9636115200105212	1.0	0.9927260849866868	2	P27144	1
+SKP1 component, POZ domain [IPR016073]	0.4176427525622199	0.0446922328267024	0.9643526248201132	1.0	0.9927260849866868	2	P63208	1
+AWS domain [IPR006560]	0.4154465592972161	0.044024712244461	0.9648847054386164	1.0	0.9927260849866868	2	O96028	1
+Post-SET domain [IPR003616]	0.4154465592972161	0.044024712244461	0.9648847054386164	1.0	0.9927260849866868	2	O96028	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.378477306002923	0.0360303285574895	0.9712581759566056	1.0	0.9927260849866868	2	P34897	1
+Rhodanese-like domain [IPR001763]	0.3770131771595873	0.0358186213596432	0.9714269848960106	1.0	0.9927260849866868	2	Q99956	1
+Nucleotidyl transferase domain [IPR005835]	0.3221438692995904	0.0350314952325576	0.9720546267156756	1.0	0.9927260849866868	3	Q9Y5P6	1
+Zinc finger, RanBP2-type [IPR001876]	0.3298832229331579	0.0333225507341377	0.9734173708585176	1.0	0.9927260849866868	8	Q92804,Q01844,P35637	3
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.351024890190337	0.0330122524640243	0.9736648169142554	1.0	0.9927260849866868	2	Q99956	1
+Dual specificity protein phosphatase domain [IPR020422]	0.351024890190337	0.0330122524640243	0.9736648169142554	1.0	0.9927260849866868	2	Q99956	1
+PPM-type phosphatase domain [IPR001932]	0.3491947291361644	0.0328719228341991	0.973776723023549	1.0	0.9927260849866868	2	Q9H0C8	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.3385797950219548	0.0321743480520457	0.974333012874146	1.0	0.9927260849866868	2	Q96CX2	1
+RuvB-like, AAA-lid domain [IPR041048]	0.3378477306002841	0.0321329370974366	0.9743660369599748	1.0	0.9927260849866868	2	Q9Y265	1
+TIP49, P-loop domain [IPR010339]	0.3378477306002841	0.0321329370974366	0.9743660369599748	1.0	0.9927260849866868	2	Q9Y265	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.3012070491674965	0.0269606201199337	0.9784911431967098	1.0	0.9927850711187094	4	Q86TI2	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "14-3-3 protein [IPR000308]", "2": "Tubulin [IPR000217]", "3": "Beta tubulin [IPR002453]", "4": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:275fa525145975decd116484adcb5d0c862a469d14816cf05dd2dd2bcde8ac39
+size 109634

interpro_family/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome B-type subunit [IPR023333]	3	7	1.979754489185152	0.0477311225269367	3.699029126213592	6.970873786407767	1.6670727234653664	0.1509307531330224	1.4503762582219135	0.1681602725795027	0.9611878160538336	0.233503072382129	0.0133191340898047	0.0432957136582515	0.0032139762811053	0.0189506401306209	0.0005732271800539

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 2150,
+    "title": "Average number of proteins per term",
+    "value": 1.2758139534883721
+}