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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Ubiquitin-conjugating enzyme, active site [IPR023313]"}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:586cdf65a8b64d4f101710d8735a42728f7bf944b3c68461d46e1d0c9feb9619
+size 68213

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.4
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C164/C164_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9805931893079456	1.4269241245663582	0.1536017662778532	0.9998961010492006	0.3249268132800742	3	Q9HB40,P10619	2
+Nucleoside diphosphate kinase, active site [IPR023005]	0.7785505124450929	0.8175505601607241	0.4136138678585586	0.999999999999822	0.63191007589502	2	P15531	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.424120234604106	0.3144103208666081	0.7532094184044988	1.0	0.9005098462814389	6	P61088,P68036,P61081,P61086,Q16763	5
+Peptidase family C14A, cysteine active site [IPR033139]	0.4668538911855519	0.2929941857046278	0.7695265959132296	1.0	0.9005098462814389	4	P55212,P55210	2
+Peptidase family C14A, His active site [IPR016129]	0.4668538911855519	0.2929941857046278	0.7695265959132296	1.0	0.9005098462814389	4	P55212,P55210	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CASP3", "CASP6", "CASP7", "CASP8", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PASK", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["CASP6", "CASP7", "CTSA", "NME1", "SCPEP1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c2e665b43d9fee8fd3baa05f7fc3abd30d1b73f5c15cfeee1c935527d1edc7ce
+size 61872

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.032258064516129
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C164/C164_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.7127238955847729	1.2702510632602464	0.2039952137455607	0.9991520191360084	0.5366044708888285	5	Q10713	1
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.403001464128845	0.0697551308737227	0.9443885605141856	1.0	0.9443885605141856	2	Q9H0C8	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Adrenodoxin, iron-sulphur binding site [IPR018298]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPNS1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FDX1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PASK", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2", "VRK1"], "leading_proteins": ["ILKAP", "PMPCA"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6019848e4965b234368a80e0c97b4b2fe8c4c049bc9f7f27bb95ca022c0abee1
+size 86850

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 264,
+    "title": "Average number of proteins per term",
+    "value": 2.496212121212121
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C164/C164_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,34 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+C-type lectin, conserved site [IPR018378]	0.9831625183016108	1.5847911871509248	0.1130137853833201	0.9999999999999822	0.3556974644679543	2	Q5KU26	1
+Tetraspanin, conserved site [IPR018503]	0.9806002928257695	1.5749726492484908	0.1152627578723368	0.9999999999999908	0.3556974644679543	2	O60637	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9787701317715968	1.5679589068071536	0.1168907228323383	0.9999999999999944	0.3556974644679543	2	Q9BTY2	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.978404099560762	1.5665561142164548	0.1172184826087576	0.9999999999999948	0.3556974644679543	2	P13473	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.9685212298682286	1.5286771324345725	0.1263445039869308	0.9999999999999996	0.3625537940494537	2	P01130	1
+Sterol reductase, conserved site [IPR018083]	0.9648609077598834	1.5146472735962362	0.1298617536502528	1.0	0.368639816813621	2	Q14739	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.9494875549048328	1.4557331575011283	0.1454664000381975	1.0	0.3879104001018601	2	P01889	1
+Chromo domain, conserved site [IPR023779]	0.7509992239327898	1.4160367280876267	0.1567647513370871	1.0	0.4018047995436019	5	Q13185,P83916,O14646	3
+Guanylate kinase, conserved site [IPR020590]	0.7827838827838836	1.3361824936600029	0.181489631653561	1.0	0.4409551270390903	4	Q14168,Q00013,O14936	3
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6518444632256541	1.2694370153720549	0.2042852412951779	1.0	0.4457132537349336	8	P28072,P20618,P49721	3
+Sugar transporter, conserved site [IPR005829]	0.8931185944363136	1.2405002673175711	0.2147904153819653	1.0	0.4610135744783646	2	Q7L0J3	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.7635431918008783	0.7650541595177581	0.4442392949112772	1.0	0.6324560963880743	2	Q16539	1
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.7602489019033756	0.7536628235623754	0.4510517104468285	1.0	0.6367788853366991	2	Q96FJ2	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.741581259150804	0.6901065189049175	0.4901272039787931	1.0	0.6774533081172848	2	P50570	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5114689404009695	0.5934640738578597	0.5528706192376516	1.0	0.7446828748915307	6	P05091	1
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.7024158125915063	0.563189685624939	0.5733057256329737	1.0	0.7509881639701896	2	O15160	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.5545633848526663	0.5343231021282834	0.5931180114028309	1.0	0.7601124029628513	4	Q13190,O15400	2
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6752105455876969	0.4559494396419572	0.6484263364242813	1.0	0.8017423035874063	3	O15347,P26583	2
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.640190336749636	0.3848945650109086	0.7003155327871526	1.0	0.8332059135006635	2	P22314	1
+Fructose-bisphosphate aldolase class-I active site [IPR029768]	0.6336017569546151	0.3680497237288266	0.7128361581936051	1.0	0.8402556623372289	2	P04075	1
+GTP1/OBG, conserved site [IPR006074]	0.5918740849194783	0.2718461170709923	0.7857403437069566	1.0	0.8855623073505953	2	Q9Y295	1
+Ribosomal protein S2, conserved site [IPR018130]	0.560029282576874	0.2114510596794125	0.8325353174608932	1.0	0.9196206017141246	2	P08865	1
+Serpin, conserved site [IPR023795]	0.5380673499268019	0.1766263603059184	0.85980188708356	1.0	0.9418576688384226	2	P50454	1
+Ribosomal protein L30, conserved site [IPR018038]	0.5204978038067434	0.1527461754363896	0.8785984452669202	1.0	0.9572438513091414	2	Q6DKI1	1
+Adenylate kinase, conserved site [IPR033690]	0.3835164835164855	0.1383885979029145	0.8899333078668932	1.0	0.9572438513091414	4	P30085,P54819,P27144	3
+Histidine triad, conserved site [IPR019808]	0.5040263543191789	0.1334708726824937	0.8938209983759553	1.0	0.9572438513091414	2	Q96C86	1
+Profilin conserved site [IPR027310]	0.4981698389458305	0.1273174108781235	0.898689180557988	1.0	0.9572438513091414	2	P35080	1
+14-3-3 protein, conserved site [IPR023409]	0.3222140762463349	0.0977583243819441	0.9221242011374996	1.0	0.9776738518084332	6	P63104,P27348,P62258,Q04917,P31946	5
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.3304029304029325	0.0826862786162157	0.9341009955859004	1.0	0.9864106513387106	4	Q8N4Q0,Q99536,Q08257	3
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.4062957540263492	0.0706969932156271	0.943638913917756	1.0	0.9880519267865748	2	Q00796	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.9880519267865748	2	Q9H9Y6	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.2967032967032987	0.0622535382198463	0.9503609277969643	1.0	0.9880519267865748	4	Q8NEB9,Q9UBF8,P42345	3
+Zinc finger, PHD-type, conserved site [IPR019786]	0.3046414497812623	0.0525242675535742	0.9581109593081938	1.0	0.9880519267865748	12	Q9BTC0,Q14839,Q9UPP1	3

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDM2A", "KDSR", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF8", "PHGDH", "PI4KB", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM35", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AK2", "AK4", "ALDH2", "ALDOA", "CASK", "CBX1", "CBX3", "CHD1", "CHD4", "CMPK1", "COLEC12", "CRYZ", "DCPS", "DIDO1", "DNM2", "DRG1", "DYNLL2", "FUCA2", "HLA-B", "HMGB2", "HMGB3", "LAMP2", "LBR", "LDLR", "MAPK14", "MPP1", "MPP2", "MTOR", "PFN2", "PHF8", "PI4KB", "PIK3C3", "POLR1B", "POLR1C", "PSMB1", "PSMB2", "PSMB6", "RPL7L1", "RPSA", "SERPINH1", "SORD", "STX5", "STX7", "SV2A", "TSPAN3", "UBA1", "VAT1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Immunoglobulin-like domain [IPR007110]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Immunoglobulin-like domain [IPR007110]", "1": "Phosphoribosyltransferase domain [IPR000836]", "2": "Zinc finger, PHD-type [IPR001965]", "3": "Alcohol dehydrogenase, N-terminal [IPR013154]", "4": "14-3-3 domain [IPR023410]", "5": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "6": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "7": "CS domain [IPR007052]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:cd40db9dfc62f97d206e4201feb2f12893980e37a3b39feda9b6f638d41363bf
+size 281984

interpro_domain/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Immunoglobulin-like domain [IPR007110]	6	8	2.2435037133204445	0.0248643506744319	4.480582524271845	12.427184466019416	0.4075261998509777	0.4433674298264088	2.6479725987944898	3.173316973839475	1.1756568118942026	0.3233613924696422	1.0	1.0	0.3043925460154114	0.0582621706836755	0.3145553855505153

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 2335,
+    "title": "Average number of proteins per term",
+    "value": 2.091648822269807
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C164/C164_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,179 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Immunoglobulin-like domain [IPR007110]	0.892633001985749	2.2435037133204445	0.0248643506744319	1.0	0.1488673303199963	8	P35613,Q9Y624,Q08722,P04439,P10321,P01889	6
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.9049410010931548	1.7820605924446098	0.0747393512361673	1.0	0.2748289529707887	4	P48147	1
+Immunoglobulin subtype 2 [IPR003598]	0.8700771503207784	1.6558088934229018	0.0977605261961356	1.0	0.3163486402802737	4	P35613,Q9Y624	2
+Immunoglobulin subtype [IPR003599]	0.8700771503207784	1.6558088934229018	0.0977605261961356	1.0	0.3163486402802737	4	P35613,Q9Y624	2
+Peptidase M16, N-terminal [IPR011765]	0.768325657494694	1.6207644751807553	0.1050681600133651	1.0	0.3228080968831679	7	Q10713,P31930,Q5JRX3	3
+Peptidase M16, C-terminal [IPR007863]	0.768325657494694	1.6207644751807553	0.1050681600133651	1.0	0.3228080968831679	7	Q10713,P31930,Q5JRX3	3
+PA domain [IPR003137]	0.989385065885798	1.6086319081118383	0.1076968528707957	1.0	0.3265872096796209	2	P02786	1
+C-type lectin-like [IPR001304]	0.9831625183016108	1.5847911871509248	0.1130137853833201	1.0	0.3361620240382836	2	Q5KU26	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.9831625183016108	1.5847911871509248	0.1130137853833201	1.0	0.3361620240382836	2	Q5KU26	1
+Ricin B, lectin domain [IPR000772]	0.8499430627297545	1.582449467775857	0.1135469994850479	1.0	0.3368897634022707	4	Q86SF2,Q9UBG0	2
+JmjC domain [IPR003347]	0.8463308417753639	1.5692583026137146	0.1165877639955947	1.0	0.3407164317017695	4	Q9UPP1,Q8IUF8	2
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9787701317715968	1.5679589068071536	0.1168907228323383	1.0	0.3407488611903996	2	Q9BTY2	1
+Chromo domain [IPR023780]	0.7640121849563617	1.5604888089483595	0.1186444125383479	1.0	0.3428647317785177	6	Q13185,Q14839,P83916,O14646	4
+Band 7 domain [IPR001107]	0.7144781069258397	1.5302774364961058	0.1259480708724338	1.0	0.3569038173387537	8	P27105,O75955,Q9UJZ1	3
+EGF-like calcium-binding domain [IPR001881]	0.9685212298682286	1.5286771324345725	0.1263445039869308	1.0	0.3571603109073651	2	P01130	1
+EGF-like domain [IPR000742]	0.9685212298682286	1.5286771324345725	0.1263445039869308	1.0	0.3571603109073651	2	P01130	1
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.9637628111273806	1.510438382895097	0.1309316008302143	1.0	0.364392476684804	2	P06865	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.9637628111273806	1.510438382895097	0.1309316008302143	1.0	0.364392476684804	2	P06865	1
+Peptidase S9A, N-terminal domain [IPR023302]	0.9626647144948765	1.5062295479709455	0.1320082566587357	1.0	0.365432071167469	2	P48147	1
+Chromo/chromo shadow domain [IPR000953]	0.7006983131725237	1.4731907802392503	0.1406996004216196	1.0	0.3737583242144277	8	Q13185,Q14839,P83916,O14646	4
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7607230056100182	1.4529898386394118	0.1462265753220255	1.0	0.3806157581633476	5	Q14168,Q00013,O14936	3
+Guanylate kinase-like domain [IPR008144]	0.7607230056100182	1.4529898386394118	0.1462265753220255	1.0	0.3806157581633476	5	Q14168,Q00013,O14936	3
+F-box domain [IPR001810]	0.8013687426869704	1.404486501000694	0.1601740286296065	1.0	0.4045302345935092	4	Q8NEZ5	1
+Marvel domain [IPR008253]	0.931185944363106	1.385665246796862	0.1658491448380687	1.0	0.4149499872532602	2	Q16625	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.7183435912778278	1.3830869544885658	0.166638205237624	1.0	0.4149499872532602	6	Q9UEU0,O15400	2
+HECT domain [IPR000569]	0.7095440592529557	1.348748438321419	0.1774177813681614	1.0	0.4253290754565266	6	Q05086,O95071	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.9498352251922372	1.3218991141558518	0.1862017474522668	1.0	0.4339209921115431	3	P10321,P01889	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.9498352251922372	1.3218991141558518	0.1862017474522668	1.0	0.4339209921115431	3	P10321,P01889	2
+Immunoglobulin C1-set [IPR003597]	0.9498352251922372	1.3218991141558518	0.1862017474522668	1.0	0.4339209921115431	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.9498352251922372	1.3218991141558518	0.1862017474522668	1.0	0.4339209921115431	3	P10321,P01889	2
+Glycosyltransferase 2-like [IPR001173]	0.914348462664714	1.321331361019881	0.1863909015365643	1.0	0.4339209921115431	2	Q86SF2	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.914348462664714	1.321331361019881	0.1863909015365643	1.0	0.4339209921115431	2	Q86SF2	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9476382277554012	1.3144062760804638	0.1887095195532915	1.0	0.4375737121717336	3	O43924,A6NIH7	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.9055636896046874	1.287838089659702	0.1978023301687312	1.0	0.4465959398485719	2	P51114	1
+K Homology domain [IPR004087]	0.5017612001507101	1.2330106910142524	0.2175717754886159	1.0	0.4673689933449109	21	P51114,Q06787,P51116,O75525	4
+Peptidase M28 [IPR007484]	0.9155750188126828	1.2053174468728702	0.2280807768645361	1.0	0.4793674841188515	3	P02786	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.7441885383067994	1.1943816855773437	0.2323286975767078	1.0	0.4849400755264898	4	Q92688	1
+Fxr1, tudor domain [IPR041560]	0.9058952764555108	1.172516131456876	0.2409898994213879	1.0	0.4879764930855425	3	P51114,Q06787	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.9058952764555108	1.172516131456876	0.2409898994213879	1.0	0.4879764930855425	3	P51114,Q06787	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.9058952764555108	1.172516131456876	0.2409898994213879	1.0	0.4879764930855425	3	P51114,Q06787	2
+Agenet-like domain [IPR008395]	0.9058952764555108	1.172516131456876	0.2409898994213879	1.0	0.4879764930855425	3	P51114,Q06787	2
+CBS domain [IPR000644]	0.6500911394187969	1.1163849451699182	0.2642573948919438	1.0	0.5059248021923276	6	P51790	1
+Jumonji, helical domain [IPR041070]	0.8594436310395359	1.1133136036370437	0.2655737659314081	1.0	0.5059248021923276	2	Q9UPP1	1
+K Homology domain, type 1 [IPR004088]	0.481367886289302	1.1050899513693992	0.2691206143151847	1.0	0.5096485275149687	21	P51114,Q06787,P51116,O75525	4
+Fibronectin type II domain [IPR000562]	0.8728357008642929	1.061190709910046	0.2886032404751613	1.0	0.5356824853016706	3	P11717	1
+Survival motor neuron [IPR010304]	0.8396778916544724	1.0395081798342924	0.2985684558026735	1.0	0.5455822606701075	2	O75940	1
+Tudor domain [IPR002999]	0.6303285590522176	1.0393949914229563	0.2986210724540183	1.0	0.5455822606701075	6	Q14739	1
+Zinc finger, CCHC-type [IPR001878]	0.6121746584854965	1.002006832075411	0.3163402931465509	1.0	0.5642892165753982	7	Q9NUD5	1
+Chromo shadow domain [IPR008251]	0.8513365067740754	0.9895755538934776	0.3223816236751053	1.0	0.5715725825978519	3	Q13185,P83916	2
+Chromo domain subgroup [IPR017984]	0.8513365067740754	0.9895755538934776	0.3223816236751053	1.0	0.5715725825978519	3	Q13185,P83916	2
+Domain of unknown function DUF5600 [IPR040990]	0.8188140556368989	0.9625250268042578	0.3357859378720769	1.0	0.5873109849672656	2	Q9H223	1
+EH domain-containing protein, N-terminal [IPR031692]	0.8188140556368989	0.9625250268042578	0.3357859378720769	1.0	0.5873109849672656	2	Q9H223	1
+Syntaxin, N-terminal domain [IPR006011]	0.8151537335285577	0.9491341293847444	0.3425523981070277	1.0	0.5937566536083922	2	O15400	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8346249693247143	0.934469372697494	0.3500618274488762	1.0	0.5990069697452386	3	Q96G23	1
+Dynamin, N-terminal [IPR045063]	0.5883467589136	0.9081292640516232	0.3638099308463682	1.0	0.6097432546235036	7	P50570,Q9H4M9,Q9H223	3
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5883467589136	0.9081292640516232	0.3638099308463682	1.0	0.6097432546235036	7	P50570,Q9H4M9,Q9H223	3
+Major facilitator superfamily domain [IPR020846]	0.8179622669961581	0.8801156629523816	0.3787966548888763	1.0	0.617660746623971	3	Q7L0J3	1
+Zinc finger, RanBP2-type [IPR001876]	0.5517552318710245	0.8521346771991409	0.3941393472226657	1.0	0.6344705076491134	8	Q92804,P35637,Q01844	3
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8059181524415997	0.8412534292853093	0.4002059742629578	1.0	0.6380919878515058	3	Q32P28	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.7785505124450929	0.8175505601607241	0.4136138678585586	1.0	0.6481801217783452	2	P15531	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7661054172767181	0.7739481500430672	0.4389614538920117	1.0	0.6661647397315124	2	O60506	1
+L27 domain, C-terminal [IPR014775]	0.782497253753204	0.7668791292098259	0.4431533836358494	1.0	0.6662995175722527	3	Q14168,O14936	2
+L27 domain [IPR004172]	0.782497253753204	0.7668791292098259	0.4431533836358494	1.0	0.6662995175722527	3	Q14168,O14936	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5539544182929186	0.7476420329464392	0.4546761042088372	1.0	0.6755968814081662	6	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5539544182929186	0.7476420329464392	0.4546761042088372	1.0	0.6755968814081662	6	Q32P28	1
+Tim44-like domain [IPR007379]	0.7576866764275326	0.7448377489506631	0.4563698114515178	1.0	0.6774466050472308	2	O43615	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.7551244509516853	0.736043870756733	0.4617039996871919	1.0	0.681465764392916	2	P20042	1
+Ubiquitin-like domain, USP-type [IPR028135]	0.7543923865300232	0.733537154310356	0.4632308754861085	1.0	0.6831573963878701	2	Q9Y4E8	1
+Dynamin GTPase effector [IPR003130]	0.741581259150804	0.6901065189049175	0.4901272039787931	1.0	0.7051429582812582	2	P50570	1
+GTPase effector domain [IPR020850]	0.741581259150804	0.6901065189049175	0.4901272039787931	1.0	0.7051429582812582	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.741581259150804	0.6901065189049175	0.4901272039787931	1.0	0.7051429582812582	2	P50570	1
+MENTAL domain [IPR019498]	0.7331625183016193	0.6620425444901049	0.5079439561697092	1.0	0.7175665537793653	2	O95772	1
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.729136163982438	0.6487627380105941	0.5164917457099345	1.0	0.7230265145279959	2	Q13526	1
+Zinc finger, CXXC-type [IPR002857]	0.7064421669106951	0.5757823478341552	0.5647623064426339	1.0	0.756489000058965	2	Q9Y2K7	1
+Domain of unknown function DUF4749 [IPR031847]	0.706076134699852	0.5746329084041566	0.5655395908788328	1.0	0.756489000058965	2	Q96HC4	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.7024158125915063	0.563189685624939	0.5733057256329737	1.0	0.7627742845316202	2	O15160	1
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.7024158125915063	0.563189685624939	0.5733057256329737	1.0	0.7627742845316202	2	O15160	1
+CARG-binding factor, N-terminal [IPR012956]	0.6844802342606187	0.5085256557264362	0.6110847514959454	1.0	0.7852519833680005	2	Q14103	1
+THIF-type NAD/FAD binding fold [IPR000594]	0.4809675204208103	0.5061776342381423	0.6127319544738745	1.0	0.7852519833680005	7	Q8TBC4	1
+p21 activated kinase binding domain [IPR033923]	0.6702049780380721	0.4668111162471326	0.640635021954191	1.0	0.7999373135096448	2	Q13177	1
+CRIB domain [IPR000095]	0.6702049780380721	0.4668111162471326	0.640635021954191	1.0	0.7999373135096448	2	Q13177	1
+Phosphoribosyltransferase domain [IPR000836]	0.4710410557184757	0.4563796197904197	0.6481170184864218	1.0	0.8058323951894542	6	P11908,P00492,P07741,O60256,P11172	5
+THUMP domain [IPR004114]	0.6606881405563705	0.439954404529608	0.6599701310730541	1.0	0.8124237246734586	2	Q9BV44	1
+Ubiquitin-associated domain [IPR015940]	0.416293795752985	0.4147599298950306	0.6783176556556663	1.0	0.8200181758764244	11	Q14157,Q13501	2
+Aminotransferase, class I/classII [IPR004839]	0.4537448709246987	0.4145239735356553	0.6784904136159537	1.0	0.8200181758764244	7	Q6YP21,O15269,O15270	3
+GTP binding domain [IPR006073]	0.410669433322038	0.3924878006560027	0.6946978234228998	1.0	0.8277370016002321	11	Q969Y2	1
+RBM4, RNA recognition motif 2 [IPR034898]	0.6427525622254784	0.3915602076569393	0.6953831944006919	1.0	0.8277370016002321	2	Q9BQ04	1
+RBM4, RNA recognition motif 1 [IPR034897]	0.6427525622254784	0.3915602076569393	0.6953831944006919	1.0	0.8277370016002321	2	Q9BQ04	1
+Ribosomal protein L11, N-terminal [IPR020784]	0.638360175695464	0.3801725286243058	0.7038173500139637	1.0	0.8304084203608735	2	P30050	1
+Ribosomal protein L11, C-terminal [IPR020783]	0.638360175695464	0.3801725286243058	0.7038173500139637	1.0	0.8304084203608735	2	P30050	1
+Rab-GTPase-TBC domain [IPR000195]	0.4459988239426313	0.3779316470732258	0.7054813720141395	1.0	0.8315492194109115	6	Q8TC07	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.4288114072790575	0.336360417936649	0.736599094230872	1.0	0.8552754276624	7	P60900,P25788	2
+Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]	0.4799533258886183	0.3245251773392142	0.7455404640324399	1.0	0.8627966035618558	4	P36915	1
+PTB/PI domain [IPR006020]	0.613368713949145	0.3098344525200435	0.756686850615472	1.0	0.8675280973211682	3	Q9UKG1	1
+Zinc finger, PHD-type [IPR001965]	0.3714702721735904	0.3077171366905215	0.7582975788576036	1.0	0.8675280973211682	15	Q9BTC0,Q9Y2K7,Q8IWS0,Q9UPP1,Q14839	5
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.6035871156661833	0.296954806064679	0.76650101308448	1.0	0.8713631283117141	2	Q9H993	1
+Peptidase C14A, caspase catalytic domain [IPR015917]	0.4668538911855519	0.2929941857046278	0.7695265959132296	1.0	0.8724306613641736	4	P55212,P55210	2
+Peptidase C14,  p20 domain [IPR001309]	0.4668538911855519	0.2929941857046278	0.7695265959132296	1.0	0.8724306613641736	4	P55212,P55210	2
+Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]	0.4668538911855519	0.2929941857046278	0.7695265959132296	1.0	0.8724306613641736	4	P55212,P55210	2
+GTP binding protein, second domain [IPR031662]	0.5918740849194783	0.2718461170709923	0.7857403437069566	1.0	0.8867586769239939	2	Q9Y295	1
+Thioesterase domain [IPR006683]	0.5786969253294352	0.2454434527315344	0.8061130873082676	1.0	0.8988892353700119	2	Q9NPJ3	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.5786969253294352	0.2454434527315344	0.8061130873082676	1.0	0.8988892353700119	2	Q9Y305	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.5761346998535927	0.2405397495401235	0.8099118519458404	1.0	0.9026941166078936	2	Q8IWA4	1
+Zinc finger, CHHC-type [IPR012996]	0.5452215305748811	0.1874513987833179	0.8513067263309666	1.0	0.9326363331019552	3	P52597,P55795	2
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.5441230318564629	0.1858408562919623	0.85256956390017	1.0	0.9326363331019552	3	O00203,Q10567	2
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3522445725169406	0.1856067811246464	0.8527531354058562	1.0	0.9326363331019552	11	Q9H7Z7	1
+Serpin domain [IPR023796]	0.5380673499268019	0.1766263603059184	0.85980188708356	1.0	0.9394653281891028	2	P50454	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5373352855051327	0.1755613504709853	0.8606385685157916	1.0	0.9395545052129352	2	Q92945	1
+NOPS [IPR012975]	0.5346027096301722	0.1723707629910862	0.8631460558869231	1.0	0.941357328582889	3	P23246,Q8WXF1	2
+AARP2CN [IPR012948]	0.533674963396779	0.1703282434031526	0.8647520007617016	1.0	0.9417891426206032	2	Q2NL82	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.533674963396779	0.1703282434031526	0.8647520007617016	1.0	0.9417891426206032	2	Q2NL82	1
+Bms1/Tsr1-type G domain [IPR030387]	0.533674963396779	0.1703282434031526	0.8647520007617016	1.0	0.9417891426206032	2	Q2NL82	1
+Zinc finger, LIM-type [IPR001781]	0.3521293423212172	0.157771394385396	0.874636940279838	1.0	0.9490135945880211	8	Q13642,Q9NR12,Q14847,Q96HC4	4
+Vps4 oligomerisation, C-terminal [IPR015415]	0.5226939970717467	0.1555410932944763	0.8763947603599589	1.0	0.950479222220392	2	P55072	1
+Ribosomal protein L30, N-terminal [IPR012988]	0.5204978038067434	0.1527461754363896	0.8785984452669202	1.0	0.9511021649041532	2	Q6DKI1	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.5204978038067434	0.1527461754363896	0.8785984452669202	1.0	0.9511021649041532	2	Q6DKI1	1
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.5204978038067434	0.1527461754363896	0.8785984452669202	1.0	0.9511021649041532	2	Q6DKI1	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.5189798367889528	0.1521514554759633	0.8790674809985091	1.0	0.9511689379664128	3	O43823	1
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.5172035139092288	0.148654169080788	0.8818265270829424	1.0	0.95371233938799	2	Q9NP81	1
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.5109993850167531	0.1427160274548059	0.8865144582164999	1.0	0.9578950763237052	3	Q9Y4E8	1
+Dehydrogenase, E1 component [IPR001017]	0.5091508052708706	0.1391526975374615	0.8893294866415831	1.0	0.959604598571209	2	P08559	1
+GINS subunit, domain A [IPR021151]	0.5027462467960455	0.1335820632346015	0.8937330685201794	1.0	0.9625768980602486	3	Q9BRT9,Q9Y248	2
+Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]	0.4987184181618456	0.1293512962571851	0.897079683782644	1.0	0.9657358513750456	3	Q14558,P11908	2
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.4970717423133319	0.1262034303562471	0.8995708960476119	1.0	0.967525583726934	2	Q9UJY5	1
+Zinc finger, PARP-type [IPR001510]	0.4948755490483262	0.1240127228739337	0.901305201431356	1.0	0.9689445880949432	2	P49916	1
+Adenylate kinase, active site lid domain [IPR007862]	0.4912152269399772	0.1204708745785011	0.9041101503052602	1.0	0.969282461415419	2	P54819	1
+Ataxin-2, C-terminal [IPR009818]	0.4860907759882881	0.1157382593943601	0.9078599833797948	1.0	0.971626454575041	2	Q14694	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.330645161290323	0.1101848818027841	0.9122627518386008	1.0	0.9739979540663616	6	Q08257,Q00796,Q8N4Q0,P11766,Q99536	5
+Uncharacterised domain CHP00451 [IPR004521]	0.47364568081991	0.1053059179779735	0.916133067220547	1.0	0.975899047426997	2	Q9ULC4	1
+Metastasis-associated protein MTA1, R1 domain [IPR035170]	0.4688872620790638	0.1016990459426999	0.9189955594484402	1.0	0.9771651326557868	2	O94776	1
+ELM2 domain [IPR000949]	0.4688872620790638	0.1016990459426999	0.9189955594484402	1.0	0.9771651326557868	2	O94776	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.348337720723049	0.0979964372828589	0.9219351223886312	1.0	0.9783026953136992	4	O60884	1
+14-3-3 domain [IPR023410]	0.3222140762463349	0.0977583243819441	0.9221242011374996	1.0	0.9783026953136992	6	P63104,P27348,P62258,Q04917,P31946	5
+Ribosomal protein L18e/L15P [IPR021131]	0.4577508735804176	0.0943251657437143	0.9248508596613644	1.0	0.9796132800545132	3	P46776	1
+Band 4.1, C-terminal [IPR008379]	0.4573416331014281	0.0940445312242026	0.925073782663898	1.0	0.9796132800545132	3	O43491,P11171	2
+SAB domain [IPR007477]	0.4573416331014281	0.0940445312242026	0.925073782663898	1.0	0.9796132800545132	3	O43491,P11171	2
+FERM adjacent (FA) [IPR014847]	0.4573416331014281	0.0940445312242026	0.925073782663898	1.0	0.9796132800545132	3	O43491,P11171	2
+DMAP1-binding domain [IPR010506]	0.4553440702781804	0.0925210876399996	0.9262840375639164	1.0	0.980005993525938	2	P26358	1
+START domain [IPR002913]	0.4538799414348441	0.0916211709792617	0.926999030188468	1.0	0.980234005197569	2	Q14849	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.451683748169835	0.0903037077260307	0.9280458738524856	1.0	0.9805371563102052	2	Q5JTZ9	1
+Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]	0.3141495601173026	0.0868137853835632	0.9308195298442524	1.0	0.9818565018135216	6	P07814,P49591,Q9NP81,Q9BW92,P26639	5
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.4430950178703462	0.0850532545662734	0.932219053032164	1.0	0.9818565018135216	3	O60884	1
+EB1, C-terminal [IPR004953]	0.4421669106881463	0.0850293495749112	0.9322380576105256	1.0	0.9818565018135216	2	Q15691	1
+Aminoacyl-tRNA synthetase, class II [IPR006195]	0.314726404700701	0.0826597999256649	0.9341220504479768	1.0	0.9823144388202664	11	P07814,P49591,Q9NP81,Q9BW92,Q15046,Q6PI48,Q9Y285,P26639,P14868,O43776	10
+Brix domain [IPR007109]	0.4375686561699012	0.081956629055462	0.9346812023788476	1.0	0.9823144388202664	3	Q9NQ55,Q9H7B2	2
+Ribosomal protein S10 domain [IPR027486]	0.4348462664714488	0.0814287787526633	0.9351009629638214	1.0	0.9823144388202664	2	P60866	1
+Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]	0.3285714285714307	0.0813080137163857	0.9351970010695724	1.0	0.9823144388202664	4	P14868,O43776,Q6PI48	3
+BAG domain [IPR003103]	0.4339772311301252	0.0800556519545499	0.9361929941004324	1.0	0.982562385032863	3	O95429	1
+KOW [IPR005824]	0.3161172161172181	0.072789919613462	0.941973292661052	1.0	0.982562385032863	4	Q92917,P61353,P62701	3
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.2968120190545943	0.0720398777586212	0.9425701724154518	1.0	0.982562385032863	5	Q8NEB9,P42345,Q9BTU6,Q9UBF8	4
+WHEP-TRS domain [IPR000738]	0.3139194139194162	0.0714356806355594	0.9430510130937636	1.0	0.982562385032863	4	P23381,P07814,P56192	3
+PPM-type phosphatase domain [IPR001932]	0.403001464128845	0.0697551308737227	0.9443885605141856	1.0	0.982562385032863	2	Q9H0C8	1
+Threonine-tRNA ligase catalytic core domain [IPR033728]	0.3960468521229817	0.0679399986648598	0.945833397965146	1.0	0.982562385032863	2	Q9BW92	1
+PSP, proline-rich [IPR006568]	0.3931185944363168	0.067242315216639	0.9463887986634852	1.0	0.982562385032863	2	Q13435	1
+Nucleotidyl transferase domain [IPR005835]	0.4020686078827879	0.0666509374913132	0.9468595936139323	1.0	0.982562385032863	3	Q9NR50	1
+Zinc finger, PHD-finger [IPR019787]	0.3045295740787526	0.066605036436477	0.9468961361553768	1.0	0.982562385032863	14	Q9BTC0,Q9Y2K7,Q14839,Q9UPP1	4
+Dynamin, GTPase domain [IPR001401]	0.3988747029645039	0.0656188075976279	0.947681315086579	1.0	0.982562385032863	3	P50570	1
+RNA-binding S4 domain [IPR002942]	0.3963052500399718	0.0648247982132014	0.9483134968541838	1.0	0.982562385032863	3	P62701	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.982562385032863	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.982562385032863	2	Q9H9Y6	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.982562385032863	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.982562385032863	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.3806734992679331	0.0646764934229353	0.9484315791582224	1.0	0.982562385032863	2	Q9H9Y6	1
+Ubiquitin-activating enzyme, SCCH domain [IPR019572]	0.366032210834558	0.0623776645049443	0.9502620814587376	1.0	0.982562385032863	2	P22314	1
+Ubiquitin-activating enzyme E1, C-terminal [IPR018965]	0.366032210834558	0.0623776645049443	0.9502620814587376	1.0	0.982562385032863	2	P22314	1
+Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]	0.366032210834558	0.0623776645049443	0.9502620814587376	1.0	0.982562385032863	2	P22314	1
+Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]	0.366032210834558	0.0623776645049443	0.9502620814587376	1.0	0.982562385032863	2	P22314	1
+Tubulin binding cofactor C-like domain [IPR012945]	0.3528550512445049	0.0608500306987076	0.951478645376004	1.0	0.982562385032863	2	O75695	1
+Replication factor C, C-terminal [IPR013748]	0.3804467228121568	0.0605898359469882	0.9516858683919608	1.0	0.982562385032863	3	P35250,P35249	2
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.34846266471449	0.0604357868628606	0.9518085569414212	1.0	0.982562385032863	2	Q8NEB9	1
+Ribosomal protein S4/S9, N-terminal [IPR001912]	0.3243045387994095	0.0588161609963791	0.9530985361308484	1.0	0.982562385032863	2	P46781	1
+Zinc finger, TFIIB-type [IPR013137]	0.2961200585651447	0.0578918853903867	0.9538347468035988	1.0	0.982562385032863	2	P29083	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.3419992676675212	0.0541586500742625	0.9568087647660076	1.0	0.983931466456886	3	Q06210,Q06203	2
+Major sperm protein (MSP) domain [IPR000535]	0.340900768949103	0.0540372782043166	0.9569054639041636	1.0	0.983931466456886	3	Q9P0L0,Q8NHP6	2
+C-CAP/cofactor C-like domain [IPR017901]	0.3350421091175395	0.0534363052205208	0.9573842791392057	1.0	0.983931466456886	3	Q15814,O75695	2
+CARP motif [IPR006599]	0.3350421091175395	0.0534363052205208	0.9573842791392057	1.0	0.983931466456886	3	Q15814,O75695	2
+Translation initiation factor, beta propellor-like domain [IPR013979]	0.2282051282051306	0.0445416552833541	0.9644726487934048	1.0	0.988171845077929	4	Q96J01,Q9NV06,Q9BY44	3
+CS domain [IPR007052]	0.2729273661041813	0.020725074625949	0.9834649666548876	1.0	1.0	8	Q9P035,Q9Y266,Q15185,Q9HB71,Q9Y2Z0,Q96RS6,Q8WVJ2	7

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "14-3-3 protein [IPR000308]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:9330e66ab9403a8ae6dbeac65ece018ee9e4679dd1ebd6d3da7ac218cf0962eb
+size 351115

interpro_family/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2734,
+    "annotations_size": 2150,
+    "title": "Average number of proteins per term",
+    "value": 1.2758139534883721
+}