| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Signaling by hedgehog 0.5827785128798558 3.172067135112603 0.0015135801262278 0.8723564477209578 0.4185457096978625 56 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,Q9BUF5,Q13885,P28074,P49721,Q9BVA1,P60900,Q96J02,P68371,Q9UL46 17 |
| Hedgehog off state 0.603666602349782 3.0353950033827117 0.0024022084795578 0.961937614476952 0.4185457096978625 51 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,Q9BUF5,Q13885,P28074,P49721,Q9BVA1,P60900,Q96J02,P68371,Q9UL46 17 |
| The role of gtse1 in g2 m progression after g2 checkpoint 0.5993654974554568 2.895264805922455 0.0037883880156044 0.99424793361974 0.4185457096978625 49 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,Q9BUF5,Q13885,P28074,P49721,Q9BVA1,P60900,P68371,Q9UL46 15 |
| Cilium assembly 0.5439800608625563 2.8280441409223784 0.0046833348491563 0.9983042033622046 0.4185457096978625 56 O43924,A6NIH7,Q13885,Q9BVA1,Q96FJ2,Q9Y496,Q10713,O95684,Q13561,Q7Z460,Q96A65,P07437,P68371,P78371,A0AVF1,O75935,P61006,Q92973,O94927,O43805,P04350,Q15154,P30153,Q9BUF5,P63167 25 |
| Sphingolipid de novo biosynthesis 0.8448441051444598 2.602115618475072 0.0092650611069617 0.9999967921513606 0.4185457096978625 10 Q06136,P27544 2 |
| Ub specific processing proteases 0.5031038261116044 2.585691512424765 0.0097183866893637 0.9999982777571348 0.4185457096978625 64 P28072,P25788,Q14997,P49720,P20618,Q15388,Q99436,P28070,Q96FW1,P28074,P49721,P60900,Q96K76,Q13546,Q9UL46 15 |
| Assembly and cell surface presentation of nmda receptors 0.82221171614478 2.5778851093296877 0.0099407043310604 0.9999987306582266 0.4185457096978625 11 Q9BUF5,Q13885,Q9BVA1,P68371,P07196,Q13555 6 |
| Glycerophospholipid biosynthesis 0.6413104443910895 2.568092844453829 0.0102259763048213 0.9999991419862144 0.4185457096978625 27 P40939,Q9NP80,Q9HCL2,Q8IV08,Q9NQZ5,Q96N66,P35790,Q9NPH0 8 |
| Metabolism of water soluble vitamins and cofactors 0.6262186541366717 2.5606427252145587 0.0104478738553619 0.9999993673536072 0.4185457096978625 33 P00374,P43490,Q96EY8,Q9H2D1,P41440,P05166,Q13057 7 |
| Pten regulation 0.4987244127932995 2.540542412147214 0.0110680668856648 0.999999730139972 0.4185457096978625 58 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,Q15022,P31751,P28074,P49721,P42345,P14373,P60900,Q9UL46 15 |
| Activation of nmda receptors and postsynaptic events 0.6798083225302222 2.539512020596259 0.011100723059005 0.999999741982804 0.4185457096978625 20 Q9BUF5,Q13885,Q9BVA1,Q13555,P07196,P68371 6 |
| Mitotic g1 phase and g1 s transition 0.5056314964746028 2.517914503609573 0.0118051972788426 0.9999999020405268 0.4185457096978625 71 P28072,P25788,P49720,P00374,P20618,Q9NR33,P28070,Q99436,P15927,Q14181,P31751,Q9NRF9,Q9Y619,P28074,P49721,P31350,P60900,Q9UL46 18 |
| Dna replication pre initiation 0.4899717546799426 2.511359280427363 0.0120267224610672 0.999999927768912 0.4185457096978625 60 P28072,P25788,Q14997,P49720,P20618,Q9NR33,P28070,Q99436,P15927,Q14181,Q9Y619,P28074,P49721,P60900,Q9UL46 15 |
| Formation of tubulin folding intermediates by cct tric 0.7472012659361392 2.4893327980179913 0.0127983102101982 0.9999999750193 0.4185457096978625 13 Q9BVA1,P68371,Q13885 3 |
| Gap junction trafficking and regulation 0.7880950715602472 2.420499136437821 0.0154992161065534 0.99999999939656 0.4185457096978625 11 Q9BVA1,P68371,Q13885 3 |
| Rho gtpases activate iqgaps 0.8033327990588465 2.4157430553018484 0.0157031381368231 0.9999999995446236 0.4185457096978625 10 Q9BVA1,P68371,Q13885 3 |
| Metabolism of vitamins and cofactors 0.5730868318396785 2.3751175383285945 0.0175433627524204 0.9999999999641987 0.4185457096978625 41 P00374,P43490,Q96EY8,Q9H2D1,O75874,P41440,P05166,Q13057 8 |
| Ras processing 0.944910613129908 2.3630250087745392 0.0181264463391332 0.9999999999840224 0.4185457096978625 5 O60725,O43924 2 |
| Intraflagellar transport 0.774046981901603 2.3547973775537834 0.0185328081582469 0.9999999999908968 0.4185457096978625 11 A0AVF1,P04350,Q9BUF5,Q13885,P63167,Q9BVA1,Q9Y496,Q96FJ2,P68371 9 |
| Uch proteinases 0.5567797440357074 2.3121855771886044 0.0207674587494335 0.999999999999589 0.4185457096978625 43 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46,Q8NB78 11 |
| Transcriptional regulation by runx1 0.4743485384706044 2.3028923697899977 0.0212848995780101 0.9999999999997996 0.4185457096978625 58 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,Q9HCL2,Q16625,P28074,P49721,Q86U86,P60900,Q96J02,Q9UL46 15 |
| Carboxyterminal post translational modifications of tubulin 0.8864653647392331 2.2940996526961785 0.0217847753154751 0.9999999999999 0.4185457096978625 6 Q9BVA1,P68371,Q13885 3 |
| Signaling by the b cell receptor bcr 0.553793738754138 2.288781639504815 0.0220920427809443 0.9999999999999348 0.4185457096978625 43 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,P28074,P49721,P60900,O43865,P62942,Q9UL46 14 |
| Intracellular signaling by second messengers 0.4874405264154133 2.273416793085351 0.0230010751067875 0.9999999999999816 0.4185457096978625 76 Q14997,P31751,O43865,Q13555,P28070,P49721,P42345,P60900,P84095,P49720,P28072,P25788,Q9UL46,P20618,Q99436,P28074,P14373,Q15022,P62993 19 |
| Synthesis of pa 0.8388861990941497 2.2653315317546587 0.0234923424668591 0.9999999999999908 0.4185457096978625 7 Q9NPH0 1 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 0.6449567845616124 2.2428715715329735 0.0249050974631113 0.9999999999999988 0.4185457096978625 18 Q9BVA1,P68371,Q13885 3 |
| Cdt1 association with the cdc6 orc origin complex 0.5660733998848355 2.2415169579777 0.0249926083221014 0.9999999999999988 0.4185457096978625 38 P28072,P49720,Q14997,P20618,Q99436,P28070,Q9Y619,P28074,P49721,P60900,Q9UL46 11 |
| Activation of ampk downstream of nmdars 0.8693669039356524 2.225527125598011 0.0260458722294445 0.9999999999999998 0.4185457096978625 6 Q9BVA1,P68371,Q13885 3 |
| Carnitine metabolism 0.9057187880130696 2.2125060431350367 0.0269317191132654 1.0 0.4185457096978625 5 P23786 1 |
| Regulation of mrna stability by proteins that bind au rich elements 0.459080112864475 2.188808904045453 0.0286107322942947 1.0 0.4185457096978625 61 P28072,P49720,Q14103,P20618,Q99436,P28070,Q92945,P28074,P49721,P60900,O95453,Q9UL46 12 |
| Orc1 removal from chromatin 0.5189164478351489 2.187189210999626 0.0287287141745922 1.0 0.4185457096978625 48 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,Q9Y619,P28074,P49721,P60900,Q9UL46 12 |
| Regulation of pten stability and activity 0.5444310259414049 2.184158324387007 0.0289506161319597 1.0 0.4185457096978625 42 P28072,P49720,Q14997,P20618,Q99436,P28070,P31751,P28074,P49721,P14373,P60900,Q9UL46 12 |
| Gap junction assembly 0.8957609955229533 2.173845875886714 0.02971671192318 1.0 0.4185457096978625 5 Q9BVA1,P68371,Q13885 3 |
| Transport of connexons to the plasma membrane 0.8957609955229533 2.173845875886714 0.02971671192318 1.0 0.4185457096978625 5 Q9BVA1,P68371,Q13885 3 |
| Synthesis of pc 0.8946993039154876 2.1697140421282888 0.030028515613679 1.0 0.4185457096978625 5 P35790 1 |
| Mitotic g2 g2 m phases 0.4873178592020851 2.158546898302833 0.0308853362458907 1.0 0.4185457096978625 85 Q14997,Q13885,Q9BVA1,O95684,P28070,Q96CW5,P49721,P60900,P07437,P68371,P49720,P28072,P25788,Q9UL46,P20618,Q99436,P28074,P63208,Q15154,Q9BUF5 20 |
| Downstream signaling events of b cell receptor bcr 0.544579594753011 2.1563720390285015 0.03105462619637 1.0 0.4185457096978625 41 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,P62942,Q9UL46 12 |
| Mapk family signaling cascades 0.4869219907949483 2.142205777433386 0.0321769268123484 1.0 0.4185457096978625 86 P28072,P49356,O43924,P49720,P20618,Q14997,Q99436,P28070,Q14168,P28074,O60725,P49721,P60900,P07196,Q13555,Q9UL46 16 |
| Degradation of gli1 by the proteasome 0.5389458418729438 2.1125706783328035 0.0346375305968869 1.0 0.4185457096978625 41 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q96J02,Q9UL46 12 |
| C type lectin receptors clrs 0.504214991224682 2.102488871928929 0.0355104734374129 1.0 0.4185457096978625 49 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,O43865,Q14790,Q9UL46 13 |
| Transcriptional regulation by runx2 0.4973140010171497 2.0849671689041553 0.0370722807812833 1.0 0.4185457096978625 50 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P31751,P28074,P49721,Q96PK6,P60900,Q9UL46 13 |
| Clec7a dectin 1 signaling 0.5200601123115443 2.0846192669166217 0.0371038741762466 1.0 0.4185457096978625 45 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,O43865,Q14790,Q9UL46 13 |
| Regulation of hmox1 expression and activity 0.5186119360167616 2.072716282758164 0.0381986915097429 1.0 0.4185457096978625 45 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Cross presentation of soluble exogenous antigens endosomes 0.5425863921078038 2.0654620980011686 0.0388792981999974 1.0 0.4185457096978625 38 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Degradation of dvl 0.5419769272721311 2.060852645142686 0.0393171002219996 1.0 0.4185457096978625 38 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Regulation of ras by gaps 0.5419769272721311 2.060852645142686 0.0393171002219996 1.0 0.4185457096978625 38 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Post chaperonin tubulin folding pathway 0.7264012541158136 2.058772431425057 0.0395160438089532 1.0 0.4185457096978625 10 Q9BVA1,P68371,Q13885 3 |
| Degradation of axin 0.5442624507405351 2.0563324859956427 0.0397504790383143 1.0 0.4185457096978625 37 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Fc epsilon receptor fceri signaling 0.4988173878329573 2.055597780636369 0.0398213019069826 1.0 0.4185457096978625 49 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,P28074,P49721,P60900,O43865,Q9UL46 13 |
| Regulation of runx3 expression and activity 0.546767215709999 2.0547493662207454 0.039903219088031 1.0 0.4185457096978625 36 P28072,P49720,P20618,P28070,P28074,P49721,P60900,Q9UL46 8 |
| Neurotransmitter receptors and postsynaptic signal transmission 0.5609822709121675 2.053592226603654 0.0400151751385406 1.0 0.4185457096978625 29 Q9BUF5,Q13885,Q9BVA1,Q13555,P07196,P68371 6 |
| Asymmetric localization of pcp proteins 0.5408628557932045 2.0524214800291545 0.040128718770231 1.0 0.4185457096978625 38 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Cargo trafficking to the periciliary membrane 0.5952173246369851 2.0343000656490755 0.0419213505769655 1.0 0.4185457096978625 20 A6NIH7,O43924 2 |
| Hedgehog ligand biogenesis 0.5297158628381836 2.0143974025469085 0.0439678268558396 1.0 0.4185457096978625 40 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Antigen processing cross presentation 0.4932288790327552 2.0068349429098458 0.0447672408609796 1.0 0.4185457096978625 49 P28072,P49720,Q14997,P20618,Q99436,P28070,Q9UIQ6,P28074,P49721,P60900,Q9UL46 11 |
| Metabolism of polyamines 0.5336303759018312 1.9975205552910504 0.0457686637868788 1.0 0.4185457096978625 38 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Stabilization of p53 0.5293285892378635 1.9871943775380216 0.0469008606860625 1.0 0.4185457096978625 39 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Phospholipid metabolism 0.5350238518069704 1.9869431144688736 0.0469287010812125 1.0 0.4185457096978625 37 Q9NP80,Q9HCL2,Q8IV08,Q9NQZ5,Q96N66,P35790,Q9NPH0 7 |
| G1 s dna damage checkpoints 0.5254176511269207 1.980936098783742 0.0475984401763418 1.0 0.4185457096978625 40 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Organelle biogenesis and maintenance 0.4685185824112107 1.9806830826172144 0.0476268251163709 1.0 0.4185457096978625 84 Q9Y512,O43924,A6NIH7,Q13885,Q9BVA1,Q9Y496,Q96FJ2,Q10713,O95684,Q13561,Q7Z460,Q86X55,Q96A65,P07437,P48735,P68371,Q16539,P78371,A0AVF1,O75935,P61006,Q13505,Q92973,O75431,O94927,O43805,P30153,Q15154,P04350,Q9BUF5,P63167 31 |
| Auf1 hnrnp d0 binds and destabilizes mrna 0.5185092635770555 1.979138883255393 0.047800371695317 1.0 0.4185457096978625 42 P28072,P49720,Q14997,Q14103,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Fceri mediated nf kb activation 0.5211464034595569 1.9729615770490985 0.0484999400972767 1.0 0.4185457096978625 41 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Transcriptional regulation by runx3 0.5268718564367295 1.9682515849390052 0.0490390975648189 1.0 0.4185457096978625 39 P28072,P49720,P20618,P28070,P28074,P49721,P60900,Q9UL46 8 |
| Transcription of the hiv genome 0.5529590135061047 1.964947711769997 0.0494202897267073 1.0 0.4185457096978625 24 Q92804,Q9H3P2,P19447,P13984,Q8IXH7,P29083 6 |
| Cyclin a cdk2 associated events at s phase entry 0.5165872470296204 1.963778688639625 0.0495557625652565 1.0 0.4185457096978625 42 P28072,P25788,P49720,P20618,Q99436,P28070,P31751,P28074,P49721,P60900,Q9UL46 11 |
| Metabolism of folate and pterines 0.7294114033608868 1.9482298370982576 0.0513874681681105 1.0 0.4185457096978625 8 Q9H2D1,P00374,P34897,P41440 4 |
| Cytoprotection by hmox1 0.4346368701075038 1.938077120483787 0.0526138143499754 1.0 0.4185457096978625 61 P28072,P25788,Q14997,P49720,P30519,P20618,Q99436,P28070,P28074,P49721,O75880,P60900,Q9UL46 13 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.7955281543535009 1.9230970667193437 0.0544678606693185 1.0 0.4185457096978625 6 P11310,Q16836 2 |
| Deubiquitination 0.4565377324235607 1.9216686285428215 0.0546474670912757 1.0 0.4185457096978625 79 P28072,Q96FW1,P49720,Q14997,P20618,Q13546,Q99436,P28070,P25788,Q15388,P28074,P49721,P60900,Q96K76,Q9UL46,Q8NB78 16 |
| Cellular response to hypoxia 0.5176197783233405 1.9199650253336205 0.054862317315337 1.0 0.4185457096978625 40 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Translocation of slc2a4 glut4 to the plasma membrane 0.5370039381542682 1.9065634237144744 0.0565771453162995 1.0 0.4185457096978625 31 Q9UIQ6,P31751,Q9BUF5,Q13885,Q9Y3B8,Q9BVA1,Q96A65,P68371 8 |
| Peroxisomal lipid metabolism 0.694291520690713 1.9053247920008607 0.0567378647082295 1.0 0.4185457096978625 10 O15254,Q9BY49,O75521,Q15067,O14734 5 |
| Recruitment of numa to mitotic centrosomes 0.5324545680584547 1.8992974547271084 0.0575253773461719 1.0 0.4185457096978625 33 O75935,O94927,O95684,Q13561,O43805,P04350,Q15154,P30153,Q9BUF5,Q96CW5,Q13885,Q7Z460,P63167,Q9BVA1,P07437,P68371 16 |
| Aggrephagy 0.6040699628213351 1.897407496194172 0.0577741770428927 1.0 0.4185457096978625 15 P04350,P08670,Q9BUF5,Q13885,Q9BVA1,Q96FJ2,P68371 7 |
| Fgfr2 alternative splicing 0.592157292920112 1.8949080573762196 0.0581045835309887 1.0 0.4185457096978625 17 P31943,P31483,P13984,Q01085,P52597,P09651 6 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0.8236725768577339 1.889030508876042 0.0588877407829055 1.0 0.4185457096978625 5 P11310,Q16836 2 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0.8236725768577339 1.889030508876042 0.0588877407829055 1.0 0.4185457096978625 5 P11310,Q16836 2 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6075676019348576 1.887317912350604 0.059117578612106 1.0 0.4185457096978625 14 Q15293,O43852,Q02818 3 |
| Tnfr2 non canonical nf kb pathway 0.5103052182118586 1.8870365217361904 0.0591554135713325 1.0 0.4185457096978625 41 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Dectin 1 mediated noncanonical nf kb signaling 0.5103052182118587 1.8870365217361904 0.0591554135713325 1.0 0.4185457096978625 41 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Defects in vitamin and cofactor metabolism 0.6900623377000542 1.8849227631369083 0.0594402663514992 1.0 0.4185457096978625 10 Q96EY8 1 |
| Formation of the early elongation complex 0.5939939435910625 1.871357446676933 0.0612955529300598 1.0 0.4271828534971862 16 P13984,P19447,Q8IXH7,Q9H3P2 4 |
| Hedgehog on state 0.5047515844284506 1.868721101286368 0.0616616266898946 1.0 0.4275415850590142 42 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Scf skp2 mediated degradation of p27 p21 0.506979815816782 1.860547848953494 0.0628080553422787 1.0 0.433279935076938 41 P28072,P49720,P20618,P28070,P28074,P49721,P60900,Q9UL46 8 |
| Interleukin 1 signaling 0.4873162387733596 1.8446663119483897 0.0650860942614202 1.0 0.4414162132468104 46 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Kinesins 0.5769100419421054 1.8403316437607216 0.0657195623492861 1.0 0.4414162132468104 18 Q9BW19,Q9BUF5,Q13885,Q9BVA1,Q99661,P68371 6 |
| Regulation of mecp2 expression and activity 0.7398289196689126 1.8394267630271488 0.065852440710991 1.0 0.4414162132468104 7 Q14739,Q13555 2 |
| Degradation of beta catenin by the destruction complex 0.4780618082980884 1.8352360443864664 0.0664707226428333 1.0 0.4414162132468104 48 P28072,P25788,Q14997,Q13363,P49720,P20618,Q99436,P28070,P63208,P28074,P49721,P60900,Q9UL46 13 |
| Establishment of sister chromatid cohesion 0.6913341516085145 1.8296259609575891 0.0673058889868507 1.0 0.4414162132468104 9 Q7Z5K2,Q29RF7 2 |
| Regulation of runx2 expression and activity 0.4961432140718066 1.826221643177072 0.067816882504871 1.0 0.4414162132468104 43 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 0.5051982328605684 1.8221497500636703 0.068432266734439 1.0 0.4414162132468104 40 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Abc family proteins mediated transport 0.46775935766062 1.8214740985754028 0.0685348204525952 1.0 0.4414162132468104 50 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Sealing of the nuclear envelope ne by escrt iii 0.6726360937642801 1.800398001388522 0.0717978161878742 1.0 0.4580902920155923 10 Q9BVA1,P68371,Q13885 3 |
| Translesion synthesis by polk 0.6844226754330235 1.7968203098231563 0.072364151002902 1.0 0.4595461738922611 9 P41440 1 |
| Negative regulation of notch4 signaling 0.5014745646056825 1.792665519031141 0.0730264231273454 1.0 0.4615949257212206 40 P28072,P49720,P20618,P28070,P28074,P49721,P60900,Q9UL46 8 |
| Abc transporter disorders 0.4945634342092237 1.786262023551091 0.074056842755741 1.0 0.4637937755993214 42 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Defective cftr causes cystic fibrosis 0.4945634342092238 1.7862620235510884 0.0740568427557415 1.0 0.4637937755993214 42 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Transmission across chemical synapses 0.5102565378480812 1.7808072027529025 0.0749439523581654 1.0 0.4671964736456275 36 P21964,Q14168,P05091,Q13885,Q9BUF5,Q9BVA1,P68371,P07196,Q13555 9 |
| Hiv transcription initiation 0.610810572790897 1.7756182158449134 0.0757958655290416 1.0 0.4682117329725797 13 P13984,P29083,Q92804,P19447 4 |
| Beta oxidation of very long chain fatty acids 0.8584743291210787 1.760510836293073 0.0783212318187258 1.0 0.4784720985439957 4 O75521,Q15067 2 |
| Mapk6 mapk4 signaling 0.4607714925454975 1.7583085939418686 0.0786950162217896 1.0 0.4784720985439957 50 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Pcp ce pathway 0.4727208649564549 1.753054471091323 0.079592657546734 1.0 0.4784720985439957 47 P28072,P49720,Q14997,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 10 |
| Signaling by notch4 0.4901118771225828 1.7500545985461076 0.0801088929453719 1.0 0.4784720985439957 42 P28072,P49720,P20618,P28070,P28074,P49721,P60900,Q9UL46 8 |
| Negative regulation of nmda receptor mediated neuronal transmission 0.7859567746188922 1.7367172350895723 0.0824370940573318 1.0 0.4784720985439957 5 Q13555,P07196 2 |
| Unblocking of nmda receptors glutamate binding and activation 0.7859567746188922 1.7367172350895723 0.0824370940573318 1.0 0.4784720985439957 5 Q13555,P07196 2 |
| Long term potentiation 0.7859567746188922 1.7367172350895723 0.0824370940573318 1.0 0.4784720985439957 5 Q13555,P07196 2 |
| Ras activation upon ca2 influx through nmda receptor 0.7859567746188922 1.7367172350895723 0.0824370940573318 1.0 0.4784720985439957 5 Q13555,P07196 2 |
| Tcr signaling 0.4683059868494739 1.7146504374511704 0.0864093355214807 1.0 0.4934045671163545 47 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Neuronal system 0.4749853899078518 1.7080839843625095 0.0876207601782126 1.0 0.496152554509129 45 Q9BUF5,P05091,Q13885,Q9BVA1,P41440,P68371,P07196,Q13555 8 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5081411325293985 1.698174758388442 0.0894747831092386 1.0 0.5012342630484857 31 O75935,P04350,Q13561,P54652,Q9BUF5,Q13885,Q9UJW0,Q9BVA1,Q96FJ2,Q9NZ32,P68371 11 |
| Tcf dependent signaling in response to wnt 0.4190312534702621 1.6869175815126043 0.0916192009107126 1.0 0.5053905166830407 57 P28072,P49720,Q14997,P20618,Q99436,P28070,P31751,P28074,P49721,P60900,Q9UL46 11 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 0.6492196187379421 1.6856907616169403 0.0918553772043495 1.0 0.5053905166830407 10 O60725,Q9HA64,P49366 3 |
| Selective autophagy 0.5059465613521547 1.6821763256826292 0.0925346534045481 1.0 0.5070749757128262 31 Q15388,P04350,P08670,Q96HS1,Q9BUF5,Q13885,P63167,Q9BVA1,Q96FJ2,P68371 10 |
| Beta catenin independent wnt signaling 0.4562229117778694 1.6786845280598597 0.093213542870532 1.0 0.5073766031851645 49 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Mitochondrial fatty acid beta oxidation 0.5660636958900366 1.6780548710580396 0.0933363876352399 1.0 0.5073766031851645 15 P11310,P05166,Q16836 3 |
| Pi3k akt signaling in cancer 0.6586247703888933 1.6734289037847303 0.0942428917697806 1.0 0.5082384520441741 9 P42345,P31751,P84095 3 |
| Interconversion of nucleotide di and triphosphates 0.5454460869084867 1.6485477327087208 0.0992403241372499 1.0 0.526826564462979 18 P31350,Q9H773 2 |
| Copi independent golgi to er retrograde traffic 0.5054980695189474 1.6463527031534566 0.0996911646611475 1.0 0.5271606722743173 26 O75935,P04350,Q13561,Q9BUF5,Q13885,Q9UJW0,Q9BVA1,Q96FJ2,Q8TD16,Q9NZ32,P68371 11 |
| Transport of inorganic cations anions and amino acids oligopeptides 0.6949897336502961 1.640166512258552 0.1009705500816018 1.0 0.528314217276459 7 Q70HW3 1 |
| Protein localization 0.4167215611741125 1.6398492642040412 0.101036512139206 1.0 0.528314217276459 69 Q9Y276,Q10713,O15254,P50402,O75874,Q9NR77,P46379,Q15388,Q99595,Q9BY49,P62072,O60830,O43615,Q15067,O14734,P28288,Q13505,O75431,O75521 19 |
| Signaling by fgfr 0.5256147650003231 1.637795695286088 0.1014643198742868 1.0 0.528314217276459 21 P31943,P31483,P13984,Q01085,P52597,P09651,P62993 7 |
| Signaling by fgfr2 0.5256147650003231 1.637795695286088 0.1014643198742868 1.0 0.528314217276459 21 P31943,P31483,P13984,Q01085,P52597,P09651,P62993 7 |
| Interleukin 1 family signaling 0.4592285387128565 1.6353381269866405 0.101978185131857 1.0 0.5289631816572281 47 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P28074,P49721,P60900,Q9UL46 11 |
| Dna replication initiation 0.69215217409359 1.627433334148906 0.1036450966699726 1.0 0.533536690812473 7 Q14181,Q9NR33 2 |
| Translesion synthesis by polh 0.6039834888062953 1.6226168085762902 0.1046713450719081 1.0 0.5367862564253703 12 P41440 1 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.8202613375459351 1.6124353758888366 0.1068672320080867 1.0 0.5455334407629575 4 Q13546,Q14790 2 |
| Transcriptional regulation by mecp2 0.6341050451020795 1.610999372462365 0.1071798592227444 1.0 0.5455334407629575 10 Q14739,Q13555 2 |
| G1 s specific transcription 0.6428230371447675 1.5971507732515111 0.1102321026961339 1.0 0.5507552483972279 9 P31350,Q9Y619 2 |
| Neddylation 0.4174211055235859 1.5931801865196715 0.1111197747463994 1.0 0.553156680880428 73 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,P61962,P28074,P49721,Q99627,Q9BTE7,P60900,Q92564,Q9UL46 15 |
| Signal amplification 0.7484469564356571 1.5832273093990314 0.1133696640703925 1.0 0.5601094918964648 5 Q14344 1 |
| G protein mediated events 0.6281718767324673 1.5815474390193307 0.1137529210915557 1.0 0.5601094918964648 10 Q13555 1 |
| Circadian clock 0.6195976504796805 1.5388599986486535 0.1238384785443249 1.0 0.5973795154454837 10 P63208,P43490 2 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0.7983735168321813 1.5269682035098926 0.1267689181808029 1.0 0.6044875782726709 4 Q16836 1 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0.7983735168321813 1.5269682035098926 0.1267689181808029 1.0 0.6044875782726709 4 Q16836 1 |
| Fatty acid metabolism 0.4304999615174143 1.5191484477599833 0.1287251341870614 1.0 0.6074217269451961 51 Q53GQ0,P40939,O15254,Q14914,P23786,P11310,Q8N8N7,Q15165,O75521,O43772,Q15067,O14734,P05166,Q16836 14 |
| Cohesin loading onto chromatin 0.6257974937082245 1.5144165719076017 0.1299202187892758 1.0 0.6097885944529804 9 Q29RF7 1 |
| Resolution of sister chromatid cohesion 0.4204487088077668 1.5057903310830498 0.1321210062135023 1.0 0.6097885944529804 53 P04350,O43683,Q9BUF5,Q13885,Q96FF9,Q8NFH4,Q9BVA1,Q96FJ2,P68371,Q99661,Q7Z5K2,Q29RF7 12 |
| Abortive elongation of hiv 1 transcript in the absence of tat 0.5402404380073109 1.5016819428297143 0.1331792694927855 1.0 0.6097885944529804 14 P13984,Q8IXH7 2 |
| Dual incision in gg ner 0.5033368299225476 1.492095410821609 0.1356741347943468 1.0 0.6097885944529804 21 P19447,Q9NR33,P15927,Q9NRF9,P18074,P41440 6 |
| Fgfr1 mutant receptor activation 0.6207239606166772 1.4896595138591058 0.1363137850016849 1.0 0.6097885944529804 9 O95684,O15164,O95429,P62993,Q9UBW7 5 |
| Visual phototransduction 0.6915475494661127 1.481135379059417 0.1385705018634664 1.0 0.6097885944529804 6 P49356,P53582 2 |
| Recycling pathway of l1 0.5015030789722038 1.4800336848680369 0.1388642573895309 1.0 0.6097885944529804 21 Q9BVA1,P68371,Q13885 3 |
| E2f mediated regulation of dna replication 0.6176560770632215 1.4746677105241088 0.1403019011484456 1.0 0.6097885944529804 9 Q9Y619,P30154,Q14181,P30153 4 |
| Slc mediated transmembrane transport 0.5169136449204638 1.4719275065903648 0.1410404547765105 1.0 0.6104266816601203 18 P53985,Q70HW3 2 |
| Activation of the pre replicative complex 0.5154615965150713 1.4628787221454291 0.1435005672384086 1.0 0.619102447228563 18 Q9Y619,Q14181,P15927,Q9NR33 4 |
| Biological oxidations 0.4581179725504447 1.444398010573971 0.148627050022688 1.0 0.637174009403259 40 Q9NUJ1,P30837,P07099 3 |
| Regulation of lipid metabolism by pparalpha 0.5700638844043613 1.4419847309964615 0.1493066811327086 1.0 0.6380747788029906 12 P23786,Q15067 2 |
| Mitotic prometaphase 0.4115332012396436 1.438637825697675 0.1502531634289736 1.0 0.6381064034374225 80 O95684,P04350,Q15154,Q13561,O43683,Q9BUF5,Q96CW5,Q13885,Q96FF9,O60566,Q8NFH4,Q9BVA1,P68371,Q96FJ2,P07437,Q99661,Q7Z5K2,Q29RF7 18 |
| Microrna mirna biogenesis 0.598004367353907 1.4307466745345945 0.1525028310757992 1.0 0.6383077574215021 10 Q9HAV4,O75569 2 |
| Antigen processing ubiquitination proteasome degradation 0.4143911095158852 1.4302369555547465 0.1526490221942518 1.0 0.6383077574215021 83 Q14997,P28070,Q05086,P49721,P60900,P55786,P49720,P28072,P25788,Q9UL46,P20618,Q99436,Q9UJX2,Q9UBS8,P28074,P19474,Q96J02,P63208,Q9UIQ6,Q9UJX4,Q9UJX3,Q13042 22 |
| Tnf signaling 0.707585004778513 1.4141244433616091 0.1573253673856829 1.0 0.6433215573725423 5 O95429,Q13546,Q14790 3 |
| Phase i functionalization of compounds 0.5251377415688909 1.413520592138535 0.1575027110497266 1.0 0.6433215573725423 14 P30837,P07099 2 |
| Hiv transcription elongation 0.491252360365383 1.4124357020442282 0.157821710391514 1.0 0.6433215573725423 21 P13984,P19447,Q8IXH7,Q9H3P2 4 |
| Cd28 co stimulation 0.6108015124570667 1.3915029551559517 0.1640729641500864 1.0 0.657849966180181 8 P42345,P31751 2 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4689480763667984 1.3866397299561215 0.1655516471181912 1.0 0.657849966180181 25 Q13126,P52597,O14979,Q9UL46 4 |
| Tp53 regulates transcription of dna repair genes 0.4633002763155614 1.3470081547637072 0.1779776063163902 1.0 0.6813283577013363 24 P19447,Q9H3P2,P13984,P18074,Q8IXH7 5 |
| Nr1h2 and nr1h3 mediated signaling 0.6825632337144614 1.3098581679890673 0.1902438208984955 1.0 0.6977389786451161 5 Q8NB78 1 |
| Cellular response to chemical stress 0.388105011720593 1.3082414871529076 0.1907914145277449 1.0 0.6977389786451161 71 P28072,P25788,Q14997,P49720,P30519,P20618,Q99436,P28070,P28074,P49721,O75880,P60900,Q9UL46 13 |
| Switching of origins to a post replicative state 0.3821637640820756 1.3061369512372107 0.1915059889879531 1.0 0.6977389786451161 57 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,Q9UJX2,Q9UJX4,Q9UJX3,Q9Y619,P28074,P49721,P60900,Q9UL46 16 |
| S phase 0.4137493780798477 1.2984285693847244 0.1941401071576864 1.0 0.7035637483394558 93 Q14997,P31751,P41440,Q7Z5K2,Q29RF7,Q9NR33,P28070,P15927,Q14181,Q96FF9,P49721,P60900,P49720,P28072,Q9UL46,P25788,P20618,Q99436,Q9UJX2,Q9Y619,Q9NRF9,P28074,P63208,Q9UJX4,Q9UJX3 25 |
| Ctla4 inhibitory signaling 0.7361202606477601 1.282131273000454 0.1997966001931281 1.0 0.7120344188651841 4 P31751,P30153 2 |
| Signaling by fgfr in disease 0.4765855397399609 1.2802085745905434 0.2004717910889408 1.0 0.7120344188651841 20 O95684,P13984,O15164,O95429,P62993,Q9UBW7 6 |
| Constitutive signaling by akt1 e17k in cancer 0.73494620954568 1.277500077659192 0.2014257530237175 1.0 0.7120344188651841 4 P31751 1 |
| Platelet sensitization by ldl 0.7347371364586213 1.2766753476806494 0.2017168883466489 1.0 0.7120344188651841 4 Q16539,P30153 2 |
| Mitochondrial protein import 0.448106524075703 1.268747277385861 0.2045312146009148 1.0 0.7186702957785833 33 Q10713,Q15388,Q9Y276,Q99595,P62072,O60830,O43615,Q13505,O75431 9 |
| Negative regulation of the pi3k akt network 0.5536993140929557 1.2585748435318571 0.2081839382013872 1.0 0.725035040477397 11 P84095,P31751,P30153,P62993 4 |
| Signaling by fgfr1 in disease 0.5626501673417117 1.252193784928335 0.2104992601424105 1.0 0.7268441303623422 10 O95684,O15164,O95429,P62993,Q9UBW7 5 |
| Signaling by cytosolic fgfr1 fusion mutants 0.6056050133875934 1.2334929816488664 0.2173918935902774 1.0 0.7367470907461022 7 O15164,Q9UBW7,O95684,P62993 4 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.7197523523992143 1.217562996546237 0.2233900833499058 1.0 0.7415247698179203 4 P11310 1 |
| Interleukin 12 signaling 0.4449998494285158 1.2167157014183358 0.2237124029619921 1.0 0.7415247698179203 27 Q13126,P52597,O14979,Q9UL46 4 |
| Cd28 dependent pi3k akt signaling 0.8883601756954613 1.2076852777093945 0.2271683430586173 1.0 0.7443264587143972 2 P31751 1 |
| Transcriptional regulation by e2f6 0.7158921802095763 1.2023383226273434 0.2292324748994068 1.0 0.748044063629594 4 P31350 1 |
| Heme signaling 0.6566507878343721 1.2015645467051703 0.2295322844249747 1.0 0.748044063629594 5 Q96EB6,P09601,Q86X55,Q15648 4 |
| Signaling by notch 0.3845933833903702 1.1962217701862476 0.2316100274699271 1.0 0.7495187941757023 54 P28072,P25788,P49720,P63208,P20618,Q99436,P28070,P28074,P49721,P60900,Q96J02,Q9UL46 12 |
| Recruitment of mitotic centrosome proteins and complexes 0.4409976902490272 1.1920195720960105 0.2332535710252208 1.0 0.7495187941757023 29 O75935,O94927,O95684,Q13561,O43805,P04350,Q15154,P30153,Q96CW5,Q7Z460,P63167,P07437,P68371 13 |
| Defective ripk1 mediated regulated necrosis 0.8839677891654464 1.190511401102552 0.233845451604487 1.0 0.7495187941757023 2 Q13546 1 |
| Tnfr1 induced proapoptotic signaling 0.8839677891654464 1.190511401102552 0.233845451604487 1.0 0.7495187941757023 2 Q13546 1 |
| Trif mediated programmed cell death 0.8839677891654464 1.190511401102552 0.233845451604487 1.0 0.7495187941757023 2 Q13546 1 |
| Tlr3 mediated ticam1 dependent programmed cell death 0.8839677891654464 1.190511401102552 0.233845451604487 1.0 0.7495187941757023 2 Q13546 1 |
| Cholesterol biosynthesis 0.4823415402395064 1.1814125379272384 0.2374388796455169 1.0 0.7592457351488411 15 Q14739,Q15392 2 |
| Disorders of transmembrane transporters 0.3780396092114347 1.1734474015870553 0.2406164379161128 1.0 0.7637926345505173 73 P28072,P25788,Q14997,P49720,P20618,O00400,Q99436,P28070,P53985,P28074,P49721,P60900,Q9UL46 13 |
| Pcna dependent long patch base excision repair 0.4721981229286907 1.1652197250987248 0.2439300632098011 1.0 0.7673633238474994 17 P15927,Q9NRF9,P41440,Q9NR33 4 |
| Beta oxidation of pristanoyl coa 0.7054664298978203 1.161237162665268 0.2455454656490296 1.0 0.7706611727876013 4 O15254 1 |
| The phototransduction cascade 0.8604906627608935 1.1538336693689897 0.2485683675361816 1.0 0.77546941300572 3 P49356,P53582 2 |
| Synthesis of dna 0.3859410411665272 1.15329504325793 0.2487893039517983 1.0 0.77546941300572 81 Q14997,P41440,Q9NR33,P28070,P15927,Q14181,P49721,P60900,P49720,P28072,P25788,Q9UL46,P20618,Q99436,Q9UJX2,Q9Y619,Q9NRF9,P28074,P63208,Q9UJX4,Q9UJX3 21 |
| Beta oxidation of butanoyl coa to acetyl coa 0.8559053301831947 1.1372574796721324 0.2554306643678194 1.0 0.7761326642052123 3 Q16836 1 |
| Neurotransmitter clearance 0.8700585651537379 1.1362826440672402 0.2558382921333404 1.0 0.7761326642052123 2 P05091 1 |
| Termination of translesion dna synthesis 0.4672677380297095 1.1346250654784136 0.2565324463064711 1.0 0.7764534399342856 17 P15927,Q9NRF9,P41440,Q9NR33 4 |
| Raf independent mapk1 3 activation 0.637832592150181 1.1228815055529604 0.2614878232160031 1.0 0.7810152785726336 5 Q99956,P36507 2 |
| Anchoring of the basal body to the plasma membrane 0.4313071475256556 1.1205865738420815 0.2624638826134204 1.0 0.782211439630786 29 O75935,O94927,O95684,Q13561,O43805,P04350,Q15154,P30153,Q7Z460,P63167,P61006,P07437,P68371 13 |
| Formation of rna pol ii elongation complex 0.4310525174725182 1.115575124206725 0.2646040450652345 1.0 0.7868641077541656 27 P13984,P19447,Q8IXH7,Q9H3P2 4 |
| Interferon gamma signaling 0.525883678234067 1.1136564159265032 0.2654266137570067 1.0 0.7875868299034325 11 Q12899,P19474,Q13555,P42224 4 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 0.8631039531478781 1.1092693345080975 0.2673140098595683 1.0 0.7914591272312709 2 O43865 1 |
| Uptake and function of anthrax toxins 0.6899506627514977 1.1001565096619343 0.2712639358215325 1.0 0.7945537907435741 4 P46734 1 |
| Dual incision in tc ner 0.4267832084643559 1.0942794464744583 0.2738324368576261 1.0 0.7985800036255664 31 P19447,Q9NR33,P15927,Q9NRF9,P18074,P41440 6 |
| Ripk1 mediated regulated necrosis 0.5191082084943206 1.078319082601684 0.2808913839476363 1.0 0.804877841190867 11 P41440,Q13546 2 |
| Collagen biosynthesis and modifying enzymes 0.5181548798013837 1.0733474410617234 0.2831152569714503 1.0 0.804877841190867 11 Q32P28,P13674 2 |
| G2 m checkpoints 0.3734946841491156 1.0719833836143604 0.2837274955678723 1.0 0.804877841190867 77 P28072,P49720,Q14997,P20618,Q99436,P28070,Q9Y619,P15927,Q9UQ84,P28074,P49721,P60900,Q9UL46 13 |
| Hiv elongation arrest and recovery 0.4566850052860393 1.0689434893170582 0.2850951339768159 1.0 0.804877841190867 17 Q8IXH7 1 |
| Costimulation by the cd28 family 0.5007100389912734 1.067150567303746 0.2859038504715001 1.0 0.804877841190867 12 P42345,P31751,P30153,P62993 4 |
| Transcriptional regulation of white adipocyte differentiation 0.567794058985774 1.0594627905012322 0.289389066608908 1.0 0.810556074913433 7 Q14966,Q86X55,P11802 3 |
| Regulation by c flip 0.8340157832290274 1.058411814695276 0.2898677353995058 1.0 0.810556074913433 3 Q13546 1 |
| Caspase activation via death receptors in the presence of ligand 0.8340157832290274 1.058411814695276 0.2898677353995058 1.0 0.810556074913433 3 Q13546 1 |
| Protein folding 0.4166226727319607 1.035348496020242 0.3005061892991854 1.0 0.8252529449840781 34 P78371,Q15477,P04350,P61962,P51784,Q9BUF5,Q13885,Q9BVA1,Q15813,P68371 10 |
| Mitotic telophase cytokinesis 0.4939574435866392 1.0305329341555838 0.302759900275849 1.0 0.8252529449840781 12 Q29RF7 1 |
| Constitutive signaling by aberrant pi3k in cancer 0.6154089064335793 1.0292971431258642 0.3033400653720903 1.0 0.8252529449840781 5 P84095 1 |
| Lagging strand synthesis 0.4502096888918275 1.0287721109702443 0.3035867749941159 1.0 0.8252529449840781 17 P15927,P41440 2 |
| Factors involved in megakaryocyte development and platelet production 0.412990032217005 1.0244885323114403 0.3056045846118429 1.0 0.8252529449840781 36 Q9BW19,Q9BUF5,Q13885,Q9BVA1,Q99661,P68371 6 |
| Ethanol oxidation 0.8235115432144073 1.0207812801173446 0.3073580754252494 1.0 0.8252529449840781 3 P30837 1 |
| Vitamin b5 pantothenate metabolism 0.668728496607218 1.0169058388188397 0.3091982254649887 1.0 0.8252529449840781 4 Q9NVE7,Q13057 2 |
| Opioid signalling 0.4577324767558413 1.0161454046912042 0.3095601500889651 1.0 0.8252529449840781 14 O43865,Q13555,P30153 3 |
| Separation of sister chromatids 0.3913125309333553 1.01262328574399 0.3112401330389716 1.0 0.8252529449840781 97 Q14997,Q13885,Q9BVA1,Q7Z5K2,Q29RF7,P28070,O43683,Q96FF9,P49721,P60900,Q99661,P68371,P49720,P28072,Q9UL46,P25788,P20618,Q99436,Q9UJX2,P28074,P04350,Q9UJX4,Q9UJX3,Q9BUF5,Q13042,Q8NFH4 26 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5834841762243131 1.009579684229644 0.3126967069945709 1.0 0.8252529449840781 6 Q14181,P30153 2 |
| Regulation of plk1 activity at g2 m transition 0.412944808298458 1.0070001486840088 0.3139347027377779 1.0 0.8252529449840781 34 P63208,O75935,O94927,O95684,Q13561,O43805,P04350,Q15154,P30153,Q7Z460,P63167,P61006,P07437,P68371 14 |
| Nuclear envelope ne reassembly 0.3935980920066942 1.0042087377140008 0.3152780113642661 1.0 0.8252529449840781 45 P50402,P04350,Q9BUF5,Q13885,Q14739,Q9BVA1,P42166,P68371 8 |
| Nod1 2 signaling pathway 0.6653927344553655 1.0038636673295382 0.3154443312087598 1.0 0.8252529449840781 4 Q96J02,Q14790 2 |
| Nicotinate metabolism 0.8185690243997621 1.0031303582244504 0.3157979688695325 1.0 0.8252529449840781 3 P43490 1 |
| Suppression of apoptosis 0.6642198385346717 0.999281240347877 0.3176584704562737 1.0 0.8252529449840781 4 P14373 1 |
| Fcgamma receptor fcgr dependent phagocytosis 0.4184849365228194 0.9924943824852098 0.3209564184007747 1.0 0.8252529449840781 23 Q9UQB8,Q8IV08,O43865,Q7L576 4 |
| Recognition of dna damage by pcna containing replication complex 0.440512630916591 0.9912759421770058 0.3215508570078675 1.0 0.8252529449840781 18 P15927,Q9NRF9,P41440,Q9NR33 4 |
| Mastl facilitates mitotic progression 0.5782815002906897 0.9868905474252984 0.3236962986873166 1.0 0.8252529449840781 6 P06493,P30154,O43768,P30153 4 |
| Perk regulates gene expression 0.4851363361327117 0.9827467898249572 0.3257320760246012 1.0 0.8255617483840471 12 O95453 1 |
| Copi dependent golgi to er retrograde traffic 0.3882454400242554 0.9797111077520854 0.3272287415388177 1.0 0.8255617483840471 46 O15260,Q9BUF5,Q13885,Q9BVA1,P68371 5 |
| Hcmv infection 0.3882074314702724 0.9793756094053392 0.3273944240013509 1.0 0.8255617483840471 46 P04350,Q99816,Q15022,Q9BUF5,Q13885,Q8NFH4,Q9BVA1,P61978,P68371 9 |
| Apc c mediated degradation of cell cycle proteins 0.3509108207628069 0.9792482676389308 0.3274573246991195 1.0 0.8255617483840471 57 P28072,P25788,Q14997,P49720,P20618,P63208,Q99436,P28070,Q9UJX2,Q9UJX4,Q9UJX3,P28074,P49721,P60900,Q9UL46 15 |
| Aurka activation by tpx2 0.4113295353449598 0.973331774015462 0.3303884354783171 1.0 0.8272324202572784 29 O75935,O94927,O95684,Q13561,O43805,P04350,Q15154,P30153,Q7Z460,P63167,P07437,P68371 12 |
| Metabolism of cofactors 0.6018833404552413 0.9730514253956692 0.3305277440763077 1.0 0.8272324202572784 5 P00374 1 |
| Hcmv early events 0.3995902789957821 0.965102212861458 0.3344936187039433 1.0 0.8325582927081667 40 P04350,Q15022,Q9BUF5,Q13885,Q8NFH4,Q9BVA1,P68371 7 |
| Telomere c strand lagging strand synthesis 0.4344090358841933 0.9528295177030508 0.3406764559436104 1.0 0.8355286995083665 18 P15927,P41440 2 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4260924922355951 0.9499090891791324 0.3421584480464568 1.0 0.8355286995083665 20 P15927,P41440,Q9NR33 3 |
| L1cam interactions 0.4012352801663599 0.9417290402961233 0.3463313830596344 1.0 0.8394036919718466 37 Q9BVA1,P68371,Q13885 3 |
| Potential therapeutics for sars 0.4053635241513674 0.9337605961136128 0.3504273995786136 1.0 0.8399132910535023 31 P49356,Q99720,P62942,P07437,Q13546 5 |
| Ovarian tumor domain proteases 0.5068667108259548 0.9272000669654904 0.3538226680811045 1.0 0.8409052104083922 9 Q96FW1,Q13546 2 |
| Signaling by ctnnb1 phospho site mutants 0.5386782503261758 0.9257924481821912 0.3545538525121476 1.0 0.8409052104083922 7 P48729,P30154,P25054,P30153 4 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 0.5386782503261758 0.9257924481821912 0.3545538525121476 1.0 0.8409052104083922 7 P48729,P30154,P25054,P30153 4 |
| Beta catenin phosphorylation cascade 0.5386782503261758 0.9257924481821912 0.3545538525121476 1.0 0.8409052104083922 7 P48729,P30154,P25054,P30153 4 |
| Gap filling dna repair synthesis and ligation in gg ner 0.4318886023896179 0.9153810712024398 0.3599916119936703 1.0 0.8457331271688183 17 P15927,P41440,Q9NR33 3 |
| Polymerase switching 0.4566252005534835 0.9135763825257106 0.3609394810171444 1.0 0.8457331271688183 13 Q14181,P41440 2 |
| Hs gag degradation 0.7931160746979127 0.9129034220964874 0.3612933375706637 1.0 0.8457331271688183 3 P08236,P54802 2 |
| Activation of nima kinases nek9 nek6 nek7 0.6403612056870973 0.9065242480300892 0.3646584364807435 1.0 0.8475772761563177 4 P06493,P53350 2 |
| Atf4 activates genes in response to endoplasmic reticulum stress 0.4936463877874227 0.901902240793557 0.3671088009264296 1.0 0.8475772761563177 10 O95453 1 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3709295738108743 0.8984708431782887 0.3689345827564572 1.0 0.8475772761563177 49 P28072,P25788,Q14997,P49720,P20618,Q99436,P28070,Q9UJX2,Q9UJX4,Q9UJX3,P28074,P49721,P60900,Q9UL46 14 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5071833291756513 0.8908776014271441 0.3729948378165415 1.0 0.8475772761563177 8 Q13555,P07196 2 |
| Erks are inactivated 0.5818491902089113 0.8902058409612046 0.3733553689058269 1.0 0.8475772761563177 5 P30154,P30153 2 |
| Regulation of tnfr1 signaling 0.6361034903089983 0.8900798368918639 0.3734230187947822 1.0 0.8475772761563177 4 Q13546,Q14790 2 |
| Activation of smo 0.8056368960468525 0.8897826103795791 0.373582625767207 1.0 0.8475772761563177 2 P48729 1 |
| Polymerase switching on the c strand of the telomere 0.4341963974802487 0.8776457047480829 0.3801360179727782 1.0 0.8567244584162613 14 Q14181,P41440 2 |
| Ptk6 regulates proteins involved in rna processing 0.7792017575979495 0.8641484265181978 0.3875063592908798 1.0 0.8675801355458085 3 O75525,Q07666 2 |
| Peroxisomal protein import 0.423128159156924 0.8614150165397477 0.3890095084163381 1.0 0.8680852576975426 17 O15254,O75874,O75521,Q15067,O14734 5 |
| Class i mhc mediated antigen processing presentation 0.3816904708717101 0.8528188000687901 0.393759796637366 1.0 0.8691723667040924 102 O95487,Q14997,P28070,Q05086,P49721,P60900,P55786,P49720,P28072,P25788,Q9UL46,P20618,Q99436,Q9UJX2,Q9UBS8,P28074,P19474,Q96J02,P63208,Q9UIQ6,Q9UJX4,Q9UJX3,Q13042 23 |
| Ros and rns production in phagocytes 0.491658196391405 0.8523333893501833 0.3940290791391647 1.0 0.8691723667040924 9 Q9Y487,P21281,Q93050 3 |
| Dna replication 0.36339590645206 0.8503721108340854 0.3951182365888748 1.0 0.8691723667040924 86 Q14997,P41440,Q9NR33,P28070,P15927,Q14181,P49721,P60900,P49720,P28072,P25788,Q9UL46,P20618,Q99436,Q9UJX2,Q9Y619,Q9NRF9,P28074,P63208,Q9UJX4,Q9UJX3 21 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7751703134544516 0.8501106771938661 0.3952635559655368 1.0 0.8691723667040924 3 Q8NB78 1 |
| Collagen formation 0.4435653763889796 0.8403660619185824 0.4007031716915428 1.0 0.8691723667040924 13 Q32P28,P13674 2 |
| Signaling by wnt 0.3499080367557732 0.8329957319182045 0.404847136398029 1.0 0.8708081046569617 76 P28072,P25788,Q14997,Q13363,P20618,P49720,Q99436,P28070,P63208,P31751,P28074,P49721,P60900,Q9HCE1,Q9UL46 15 |
| Flt3 signaling 0.7695505077572894 0.8306139729779313 0.4061917385661377 1.0 0.8708081046569617 3 P31751 1 |
| Dag and ip3 signaling 0.5173248066769645 0.8285069844830487 0.4073834410818255 1.0 0.8708081046569617 7 Q13555 1 |
| Class i peroxisomal membrane protein import 0.4790181411841784 0.8282472254759613 0.4075305037246708 1.0 0.8708081046569617 10 Q9NR77,P28288 2 |
| Flt3 signaling in disease 0.6181413751285494 0.8211650492114828 0.4115522617021085 1.0 0.8729795553282681 4 Q9UBW7 1 |
| Signaling by flt3 fusion proteins 0.6181413751285494 0.8211650492114828 0.4115522617021085 1.0 0.8729795553282681 4 Q9UBW7 1 |
| Mrna capping 0.4400177331504336 0.8205649120159118 0.4118941408386323 1.0 0.8729795553282681 13 P13984,P19447 2 |
| Coenzyme a biosynthesis 0.7829428989751188 0.8056770130431878 0.4204291070867536 1.0 0.874981862987593 2 Q13057 1 |
| Regulation of tp53 expression and degradation 0.4818686403297546 0.8044171343625027 0.4211561088760835 1.0 0.8751546666094764 9 P42345,P30154,P31751,P30153 4 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5351846713290771 0.8005403525667568 0.4233977936915887 1.0 0.8767383046675286 6 Q15067 1 |
| Recycling of eif2 gdp 0.5071365041314002 0.7824580915451844 0.4339454053676237 1.0 0.8811940782772754 7 Q9UI10,P49770 2 |
| Insulin receptor recycling 0.4697010522082135 0.7816280057278167 0.4344332232093943 1.0 0.8811940782772754 10 Q9Y487,P21281,Q93050 3 |
| Tryptophan catabolism 0.7763543191800963 0.7816213940639242 0.4344371099674573 1.0 0.8811940782772754 2 Q6YP21 1 |
| Role of phospholipids in phagocytosis 0.7546763470254692 0.779450089006918 0.4357146277262715 1.0 0.8824682251564875 3 Q8IV08 1 |
| Interleukin 12 family signaling 0.3834724905610618 0.7697342974052381 0.4414575207995306 1.0 0.8853316484634293 30 Q13126,P52597,O14979,Q9UL46 4 |
| Rho gtpases activate formins 0.3540328792762254 0.7694924306834904 0.4416010363104186 1.0 0.8853316484634293 50 P04350,O43683,Q9BUF5,Q13885,Q8NFH4,Q9BVA1,Q96FJ2,Q9NSV4,Q99661,P68371 10 |
| Alpha oxidation of phytanate 0.7492779703817715 0.7610522573999785 0.4466258550260444 1.0 0.8862964682753783 3 Q9BY49 1 |
| Hdr through homologous recombination hrr 0.3965942987950445 0.7586875353215087 0.448039495000136 1.0 0.8862964682753783 20 P15927,P41440,Q9UQ84,Q9NR33 4 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3961747385295717 0.7559945958240734 0.4496524358388503 1.0 0.8881942736991244 20 P15927,P41440,Q9NR33 3 |
| Mtor signalling 0.4526203767175668 0.7344814029928003 0.4626553903581425 1.0 0.8976331461560985 11 P31751,P62942 2 |
| Glutathione synthesis and recycling 0.5423097120680977 0.7293762496012356 0.4657715418314185 1.0 0.8976331461560985 5 Q8WUX2,Q96KP4 2 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5935743409048596 0.7284065211101666 0.4663647725713082 1.0 0.8976331461560985 4 P30153 1 |
| Spry regulation of fgf signaling 0.7386842006115555 0.7252405694651337 0.4683044581856694 1.0 0.8976331461560985 3 P62993 1 |
| Negative regulation of fgfr4 signaling 0.7386842006115555 0.7252405694651337 0.4683044581856694 1.0 0.8976331461560985 3 P62993 1 |
| Negative regulation of fgfr3 signaling 0.7386842006115555 0.7252405694651337 0.4683044581856694 1.0 0.8976331461560985 3 P62993 1 |
| Negative regulation of fgfr2 signaling 0.7386842006115555 0.7252405694651337 0.4683044581856694 1.0 0.8976331461560985 3 P62993 1 |
| Negative regulation of fgfr1 signaling 0.7386842006115555 0.7252405694651337 0.4683044581856694 1.0 0.8976331461560985 3 P62993 1 |
| Resolution of abasic sites ap sites 0.3783127559243931 0.716192923305179 0.4738722321405286 1.0 0.902675638171944 23 P15927,P41440,Q9NR33,Q9NRF9 4 |
| Dna damage bypass 0.3712343640936995 0.6975935944947408 0.4854313886107975 1.0 0.9120235226875052 24 P15927,P41440,Q9NR33 3 |
| Mucopolysaccharidoses 0.585242160469243 0.697431345778829 0.4855328904851754 1.0 0.9120235226875052 4 P08236,P54802 2 |
| Nuclear receptor transcription pathway 0.7518301610541795 0.6937674421468608 0.4878280635389456 1.0 0.9120235226875052 2 Q9UHY1 1 |
| Pp2a mediated dephosphorylation of key metabolic factors 0.7287856880068113 0.6921573707696951 0.4888385063428515 1.0 0.9125433106043066 3 P30153 1 |
| Signaling by erbb4 0.5052667474741895 0.674078202682557 0.5002615966152186 1.0 0.9274427720880316 6 Q96J02,P62993 2 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 0.3950794615353378 0.6628029512021743 0.5074567632795586 1.0 0.935730992261764 15 Q96J02,Q13546,Q14790 3 |
| Signaling by insulin receptor 0.3967357440039019 0.6611162246923245 0.5085377810818419 1.0 0.9362615191676334 14 P31751,Q93050,P21281,P62993,Q9Y487 5 |
| Ksrp khsrp binds and destabilizes mrna 0.4377919946063262 0.6596291530060312 0.509491841218009 1.0 0.9362615191676334 11 Q16539,Q15024,O95453,Q92945 4 |
| Dna damage reversal 0.7111915228943475 0.6343599588446065 0.5258459347189961 1.0 0.9515640816020184 3 Q6P6C2 1 |
| Transcriptional activation of mitochondrial biogenesis 0.4390134195014153 0.6305045145087145 0.5283645500314862 1.0 0.953582235714196 10 O00411,Q15648,Q86X55,P48735,P00367 5 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4501700632460981 0.6215781544216075 0.5342192892675783 1.0 0.9625813281405982 8 Q9Y3B8,Q86X55 2 |
| Tp53 regulates transcription of cell cycle genes 0.38767972224874 0.6100359430307709 0.5418379981081478 1.0 0.9688918939854906 14 P06493,Q99873,Q92600,Q9Y3B8,Q86X55,P24941,Q9C0C2 7 |
| Signaling by notch1 0.4754805915277653 0.5521792629051855 0.5808255405447937 1.0 1.0 6 Q96J02 1 |
| Small interfering rna sirna biogenesis 0.5442604273557681 0.5497934996870808 0.5824610176459091 1.0 1.0 4 O75569,Q15631 2 |
| Wax and plasmalogen biosynthesis 0.6836323690955693 0.5468328625043054 0.5844935637167725 1.0 1.0 3 O00116,Q6IAN0 2 |
| Apoptosis 0.3359109586729468 0.5405703363778367 0.5888037685149528 1.0 1.0 88 P28072,P49720,Q14997,P25788,P20618,Q99436,P28070,P30419,Q16625,P31751,P28074,P49721,Q9Y3B8,Q96FJ2,P60900,Q13546,Q14790,Q9UL46 18 |
| Mhc class ii antigen presentation 0.3200290426603117 0.5078282955391317 0.6115737643415879 1.0 1.0 52 O95487,P04350,Q13561,Q9BUF5,Q13885,Q9UJW0,Q9NZ32,Q9BVA1,Q96FJ2,Q99661,P68371 11 |
| Negative regulation of mapk pathway 0.4126461869724722 0.5050943061337266 0.613492600345706 1.0 1.0 10 P36507,Q99956,P30153 3 |
| Negative regulators of ddx58 ifih1 signaling 0.4628394487229984 0.5020843744333001 0.6156081711108159 1.0 1.0 6 Q96J02 1 |
| Rhov gtpase cycle 0.3659835793863087 0.498592503338928 0.6180664874791515 1.0 1.0 15 Q8TAA9,O43396,Q9NNW5 3 |
| Autophagy 0.3359776976393139 0.4982119076179659 0.6183346904306237 1.0 1.0 44 Q15388,P04350,Q99816,P08670,Q96HS1,Q9BUF5,Q13885,P42345,Q9BVA1,Q96FJ2,P68371 11 |
| Cyclin a b1 b2 associated events during g2 m transition 0.4104702657032745 0.4949906475708842 0.6206067222576863 1.0 1.0 10 P30154,P30153,P06493,P24941,P14635,P53350 6 |
| Phosphorylation of emi1 0.6653240571219334 0.4910595055861273 0.6233843611900338 1.0 1.0 3 P06493,P53350 2 |
| Death receptor signalling 0.3470573017339088 0.4677936920261999 0.6399321320176328 1.0 1.0 21 O95429,Q14344,Q13546 3 |
| Cdc42 gtpase cycle 0.3379173371290061 0.4611108507855293 0.6447190772252429 1.0 1.0 26 Q8TAA9,Q9UQB8,Q14739,A4D1P6,P42166,Q9NSV4,Q14344 7 |
| Akt phosphorylates targets in the cytosol 0.6550714024166973 0.4607657102749504 0.6449667053701884 1.0 1.0 3 P49841,P31751 2 |
| Caspase activation via extrinsic apoptotic signalling pathway 0.4696257214286585 0.4516966035905471 0.6514875653592749 1.0 1.0 5 Q13546 1 |
| Metabolism of steroids 0.3294230196875501 0.4457046189311705 0.6558106276698112 1.0 1.0 44 O95487,Q13907,Q53GQ0,P53992,P48449,Q15648,Q9HCL2,O95772,P38435,Q16850,Q15125,Q96SU4,Q14739,Q86X55,Q14534,O14734,Q8NBQ5,Q15392 18 |
| Regulation of insulin secretion 0.3924463710559578 0.4399408294996985 0.6599799632833758 1.0 1.0 11 P11166,O43865 2 |
| Ion transport by p type atpases 0.4275239015114842 0.4390106690756807 0.6606538056602629 1.0 1.0 7 Q9HD20 1 |
| Maturation of sars cov 2 nucleoprotein 0.461245880016207 0.422009503311215 0.6730180808961883 1.0 1.0 5 P48729 1 |
| Rora activates gene expression 0.6411570853167338 0.4208312587895999 0.6738783041449992 1.0 1.0 3 Q86X55,Q15648 2 |
| Mtorc1 mediated signalling 0.3989714980293919 0.4174999386885505 0.6763127691423738 1.0 1.0 9 P62942 1 |
| Extension of telomeres 0.3311952207098402 0.4171704927000016 0.6765537064399414 1.0 1.0 26 P15927,P41440 2 |
| Protein protein interactions at synapses 0.3642738321847816 0.4164345942797976 0.6770920185605434 1.0 1.0 13 P41440 1 |
| Ptk6 regulates cell cycle 0.6654465592972233 0.4135222145008553 0.6792240502228242 1.0 1.0 2 P11802 1 |
| Signaling by ptk6 0.3910530643526172 0.4068826732991465 0.6840941623558856 1.0 1.0 10 O75525,Q07666,P11802,Q8IZL8 4 |
| Transcription coupled nucleotide excision repair tc ner 0.3244999497213365 0.3962351080128799 0.691931593875255 1.0 1.0 43 P19447,Q9NR33,P15927,Q9NRF9,P18074,P41440,Q99627 7 |
| Complex i biogenesis 0.3276277189158495 0.3941896534115511 0.6934410239581703 1.0 1.0 26 Q16718,O43676,O96000,O95168,O75306,Q7L592 6 |
| G2 m dna replication checkpoint 0.6300476438836804 0.3899903238617449 0.696543702013912 1.0 1.0 3 P06493 1 |
| Programmed cell death 0.3328168308668042 0.3880523951472436 0.6979772599699221 1.0 1.0 99 P28072,P49720,Q14997,P20618,Q99436,P28070,Q16625,P31751,P28074,P49721,Q9Y3B8,P41440,P60900,Q13546,Q14790,Q9UL46 16 |
| Golgi to er retrograde transport 0.2958323616834615 0.3860853005756569 0.699433495906705 1.0 1.0 67 O15260,P04350,Q9BW19,Q13561,Q9BUF5,Q13885,Q6NUQ1,Q9UJW0,Q9NZ32,Q9BVA1,Q96FJ2,Q8TD16,Q99661,P68371 14 |
| Maturation of sars cov 1 nucleoprotein 0.6548316251830171 0.3831910723619189 0.7015780970016654 1.0 1.0 2 P49841 1 |
| Regulation of localization of foxo transcription factors 0.4311171803798144 0.382028550796774 0.7024401874152231 1.0 1.0 6 P31751 1 |
| Signaling by wnt in cancer 0.3903326081894306 0.3803826255279012 0.7036614099079146 1.0 1.0 9 Q13363,P30154,P30153,P48729,P25054 5 |
| Rhou gtpase cycle 0.3401872155402982 0.3759407083686921 0.7069609757456727 1.0 1.0 17 Q8TAA9,O43396,Q9NNW5,P62993 4 |
| Cytosolic sensors of pathogen associated dna 0.3415381124475788 0.3750234063907404 0.7076430591596985 1.0 1.0 16 P19474 1 |
| Polo like kinase mediated events 0.6209619383580026 0.3655000513985849 0.7147381684505445 1.0 1.0 3 P53350 1 |
| Cyclin d associated events in g1 0.384472067235286 0.3557042601700234 0.7220620542834641 1.0 1.0 9 P63208,P11802,P30153 3 |
| Citric acid cycle tca cycle 0.3334284598313062 0.3488549682227918 0.7271981939184289 1.0 1.0 18 P48735,Q13423 2 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3775299875101161 0.3270376941345757 0.743639375567569 1.0 1.0 9 Q96J02,Q14790 2 |
| Mitochondrial calcium ion transport 0.3324920626854448 0.3226998778797232 0.7469225446394974 1.0 1.0 15 Q10713,Q8WWC4,P45880 3 |
| Rho gtpases activate wasps and waves 0.3323756663660897 0.3180323209234796 0.7504604201652865 1.0 1.0 14 Q9UQB8,Q7L576 2 |
| Base excision repair 0.3150693926264067 0.3154154416211031 0.7524462440514679 1.0 1.0 26 P15927,P41440,Q9NR33,Q9NRF9 4 |
| Activation of bh3 only proteins 0.3630325290281844 0.3088553851201812 0.7574315360976136 1.0 1.0 11 Q9Y3B8,Q96FJ2,P31751 3 |
| Ion channel transport 0.314145392690714 0.3055251677798558 0.7599662046124598 1.0 1.0 23 Q93050,Q9HD20,P21281,Q13555,Q9Y487 5 |
| Mitotic metaphase and anaphase 0.3526284565102306 0.3010813666349513 0.7633524494442991 1.0 1.0 127 Q14997,Q13885,Q9BVA1,Q7Z5K2,Q29RF7,P50402,P28070,O43683,Q96FF9,P49721,Q14739,P60900,Q99661,P68371,P49720,P28072,Q9UL46,P25788,P20618,Q99436,Q9UJX2,P28074,P04350,Q9UJX4,Q9UJX3,Q9BUF5,Q13042,P42166 28 |
| Signaling by interleukins 0.3242081328545642 0.2854066873891445 0.7753325847178081 1.0 1.0 101 Q14997,P22626,Q13126,P28070,P08670,P49721,P51809,P60900,P14174,P49720,P28072,P25788,Q9UL46,Q16539,P20618,Q99436,O14979,P28074,P63208,P52597,P46734,P62993 22 |
| Dna strand elongation 0.3110676861010173 0.2852234842552377 0.7754729294621829 1.0 1.0 27 P15927,P41440 2 |
| Response to elevated platelet cytosolic ca2 0.3131160173847966 0.2813560219521977 0.7784373455804223 1.0 1.0 31 O43852,Q8NBX0 2 |
| Activated tak1 mediates p38 mapk activation 0.5831668188465504 0.2713905965860475 0.7860906335944271 1.0 1.0 3 P46734 1 |
| Signalling to erks 0.3633799370170103 0.2706865726381047 0.7866321048833143 1.0 1.0 9 P36507,P62993 2 |
| Activation of atr in response to replication stress 0.3182444882811986 0.2628806027134656 0.7926426074316892 1.0 1.0 17 Q9Y619 1 |
| Deactivation of the beta catenin transactivating complex 0.3810054604862329 0.2628121446461804 0.7926953744287966 1.0 1.0 7 P31751 1 |
| Regulated necrosis 0.3165829274101392 0.2611369786902143 0.7939868758597524 1.0 1.0 18 P41440,Q13546 2 |
| Diseases of signal transduction by growth factor receptors and second messengers 0.3563480477015466 0.2552562081359573 0.7985252206502416 1.0 1.0 136 Q14997,Q13363,Q99956,P31751,O15164,Q13555,P36507,O95684,P28070,P13984,P48729,P49721,P42345,P60900,Q9UBW7,P62942,P84095,P49720,P28072,Q9UL46,P51114,P25788,P20618,Q99436,P28074,O95429,P63208,P62993 28 |
| Global genome nucleotide excision repair gg ner 0.3087604525110483 0.2526368472456371 0.8005488534531424 1.0 1.0 38 P19447,Q9NR33,P15927,Q9NRF9,P18074,P41440,Q99627 7 |
| Synthesis of very long chain fatty acyl coas 0.3932806498854058 0.2525604530845525 0.8006078932580427 1.0 1.0 6 Q53GQ0 1 |
| Iron uptake and transport 0.31280875025335 0.2423515694249229 0.8085077578591593 1.0 1.0 18 Q9Y487,P30519,P21281,Q93050 4 |
| Parasite infection 0.3155147352255082 0.2412405353679347 0.8093686957596633 1.0 1.0 15 Q9UQB8,Q7L576 2 |
| Homologous dna pairing and strand exchange 0.3363793585364952 0.2389683220910594 0.8111301464838072 1.0 1.0 12 Q9UQ84 1 |
| Hdr through single strand annealing ssa 0.3363793585364952 0.2389683220910594 0.8111301464838072 1.0 1.0 12 Q9UQ84 1 |
| Formation of incision complex in gg ner 0.3261158635292734 0.2386059417576383 0.8114111573392633 1.0 1.0 13 P15927,P19447 2 |
| Signaling by vegf 0.3037209192784157 0.2327593872965294 0.8159482510250529 1.0 1.0 22 Q9UQB8,P31751,P42345,O43865,Q7L576 5 |
| Activation of bad and translocation to mitochondria 0.3559997680857062 0.2278544718633154 0.8197593778848224 1.0 1.0 8 P31751 1 |
| Rac2 gtpase cycle 0.3035361219685462 0.2259349038537902 0.8212520502806775 1.0 1.0 30 P50402,Q8TAA9,Q14739,P42166,Q13505,Q7L576 6 |
| Regulation of tp53 activity through phosphorylation 0.2990617223363189 0.2206553082397435 0.8253608325434936 1.0 1.0 26 Q92804,Q9UQ84 2 |
| Processing of smdt1 0.340189445110276 0.2160277369483426 0.8289661270408348 1.0 1.0 11 Q10713,Q8WWC4 2 |
| Oncogene induced senescence 0.3958572265261963 0.2156021493625861 0.8292978802558064 1.0 1.0 5 Q9HCE1 1 |
| Met activates ras signaling 0.433087345407915 0.2140800135155664 0.8304846613997887 1.0 1.0 4 P62993 1 |
| Fceri mediated ca 2 mobilization 0.5500406390584873 0.2003306308672574 0.8412220081057338 1.0 1.0 3 O43865 1 |
| Regulation of cholesterol biosynthesis by srebp srebf 0.296768779026765 0.1961053637433125 0.8445276981149901 1.0 1.0 22 O95487,Q13907,P53992,P48449,Q9HCL2,Q16850,Q14534,Q86X55 8 |
| Heme biosynthesis 0.3726498183312016 0.1899026087487673 0.8493854481839378 1.0 1.0 6 P36551,P50336 2 |
| Rhog gtpase cycle 0.2978923155133348 0.1890452319603947 0.8500573659198725 1.0 1.0 31 P50402,Q7L576,Q8TAA9,Q16718,Q14739,P42166,Q9NSV4,P84095 8 |
| Rhod gtpase cycle 0.2895194253713229 0.1821832211838263 0.8554389401937794 1.0 1.0 24 P50402,Q14739,P42166,Q8TAA9 4 |
| Pexophagy 0.5684480234260683 0.1809921181039163 0.8563737626865493 1.0 1.0 2 P50542 1 |
| Rhobtb1 gtpase cycle 0.2979264339035721 0.1770084600389048 0.8595017443623669 1.0 1.0 19 P78371,O43396,P08670,P62995,P07910,Q7Z6E9,P38159 7 |
| Rhoc gtpase cycle 0.2939237712597531 0.1746544221630795 0.8613511830379621 1.0 1.0 29 Q8TAA9,Q14739,P42166,P41440,P28288 5 |
| Oxidative stress induced senescence 0.3288555880376197 0.1735139910187448 0.8622474314373287 1.0 1.0 11 Q16539,P46734,Q9HCE1,Q15022 4 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3275976695172104 0.168954509760046 0.8658324228557235 1.0 1.0 11 P50402 1 |
| Signaling by braf and raf1 fusions 0.2891497470932539 0.157585141936868 0.8747837122899886 1.0 1.0 22 O15164,Q7Z2W4,Q96PU8,Q9NRY5,Q13555,P36507,P51114 7 |
| Raf activation 0.3265760817838192 0.1513298758238917 0.8797155031610098 1.0 1.0 10 P36507,Q13555,P30153 3 |
| Foxo mediated transcription 0.329790471508997 0.1500594084383617 0.8807177446663506 1.0 1.0 9 P31751 1 |
| Hiv infection 0.3339028125127896 0.1497521951795054 0.8809601266507103 1.0 1.0 125 Q14997,Q9H3P2,Q8IXH7,P28070,P13984,P49721,P29083,P60900,P49720,P28072,P25788,Q9UL46,P20618,Q99436,Q99816,P28074,P63208,Q92804,P19447,Q8NFH4,P30419 21 |
| Metabolism of porphyrins 0.3259723407542189 0.1492839594394524 0.8813295719530447 1.0 1.0 10 P30519 1 |
| Rac3 gtpase cycle 0.2866625684974731 0.1401682395069272 0.88852706533407 1.0 1.0 28 P50402,Q8TAA9,Q9UQB8,Q14739,P42166,Q7L576 6 |
| Rac1 gtpase cycle 0.2903701843213863 0.1376967932964601 0.8904800538376143 1.0 1.0 34 P50402,Q8TAA9,Q9UQB8,Q14739,P42166,Q14344,Q7L576 7 |
| Metabolism of lipids 0.3620646679375925 0.1361137376925356 0.8917313674944884 1.0 1.0 157 O95487,P23786,Q9NP80,Q8IV08,Q9NQZ5,Q06136,Q16836,Q9NPH0,Q15392,Q10713,O15254,Q8N8N7,P27544,O43772,Q14739,P05166,P35790,Q15125,Q15067,O14734,Q96N66,Q53GQ0,Q96G23,Q9HCL2,P11310,O75521 26 |
| Extracellular matrix organization 0.2846543906319281 0.1354667235660769 0.8922428724455882 1.0 1.0 27 Q32P28,P55081,P13674,O75718 4 |
| Pyruvate metabolism and citric acid tca cycle 0.2869750115493688 0.1317441124213723 0.8951866929206456 1.0 1.0 30 P53985,P48735,Q13423 3 |
| Initiation of nuclear envelope ne reformation 0.2897205724789436 0.1311310151000043 0.8956716664938149 1.0 1.0 16 P50402,Q14739 2 |
| Response of eif2ak1 hri to heme deficiency 0.5104357378249725 0.1307483732014392 0.8959743644913678 1.0 1.0 3 P08243,P20042 2 |
| Myd88 independent tlr4 cascade 0.286015474136654 0.1198028938768312 0.904639289474422 1.0 1.0 18 P63208,P46734,Q13546,Q14790 4 |
| Regulation of tp53 activity through acetylation 0.3154522968364677 0.1148661887611452 0.9085511851210556 1.0 1.0 10 P31751 1 |
| Rhobtb2 gtpase cycle 0.2846292083787676 0.1140299446763456 0.9092140558396182 1.0 1.0 18 P07910,O43396,P62995,P38159 4 |
| Host interactions of hiv factors 0.2926607789511627 0.1120304115620608 0.910799293409982 1.0 1.0 90 P28072,P49720,Q14997,P25788,P20618,P63208,Q99436,P28070,P28074,P49721,P60900,Q9UL46 12 |
| Nef and signal transduction 0.523426061493419 0.1106118267718731 0.9119241686331674 1.0 1.0 2 P63000 1 |
| Mrna decay by 3 to 5 exoribonuclease 0.2918398977066233 0.1045402439485706 0.9167406331692288 1.0 1.0 13 Q969T7,Q15477,Q6PGP7,Q9NQT5,Q15024 5 |
| Gaba b receptor activation 0.4891980959355547 0.1005288766185092 0.9199244587264616 1.0 1.0 3 P08754,P63096 2 |
| Adenylate cyclase inhibitory pathway 0.4891980959355547 0.1005288766185092 0.9199244587264616 1.0 1.0 3 P08754,P63096 2 |
| Adp signalling through p2y purinoceptor 12 0.4891980959355547 0.1005288766185092 0.9199244587264616 1.0 1.0 3 P08754,P63096 2 |
| G alpha z signalling events 0.4891980959355547 0.1005288766185092 0.9199244587264616 1.0 1.0 3 P08754,P63096 2 |
| Gaba receptor activation 0.4891980959355547 0.1005288766185092 0.9199244587264616 1.0 1.0 3 P08754,P63096 2 |
| Transferrin endocytosis and recycling 0.3065484126027883 0.0977377690812849 0.9221405237293994 1.0 1.0 11 Q9Y487,P21281 2 |
| Copi mediated anterograde transport 0.272377310778768 0.0969991506837422 0.9227270689262634 1.0 1.0 51 Q9BVA1,P68371,Q13885 3 |
| Diseases of immune system 0.5036603221083538 0.0872832303514506 0.9304463833851364 1.0 1.0 2 P09429 1 |
| Nf kb is activated and signals survival 0.5036603221083535 0.0872832303514503 0.9304463833851366 1.0 1.0 2 Q13501 1 |
| P75ntr signals via nf kb 0.5036603221083535 0.0872832303514503 0.9304463833851366 1.0 1.0 2 Q13501 1 |
| Regulation of tp53 activity 0.2815248165907829 0.0859232002524645 0.9315274685765536 1.0 1.0 40 O60921,Q16539,Q92804,P30153,P15927,P31751,Q9UQ84,P42345,O14744 9 |
| Transcriptional regulation by tp53 0.3000107837535026 0.0820623059984938 0.9345971674439806 1.0 1.0 100 Q16539,Q92804,P19447,Q9H3P2,P13984,Q9NYV4,P15927,Q9UQ84,P31751,P18074,Q9Y3B8,O75880,Q8IXH7,P42345,O14744,Q92600,Q86X55,Q9HCE1 18 |
| Signaling by fgfr1 0.3659541019448241 0.0816909213190252 0.9348924979678472 1.0 1.0 4 P62993 1 |
| Signaling by fgfr3 0.3659541019448241 0.0816909213190252 0.9348924979678472 1.0 1.0 4 P62993 1 |
| Signaling by fgfr4 0.3659541019448241 0.0816909213190252 0.9348924979678472 1.0 1.0 4 P62993 1 |
| Chromatin modifying enzymes 0.2730347397685521 0.0801311183741525 0.93613297343326 1.0 1.0 49 O95619,P11802,Q15022,Q9H7B4,Q99873,Q86U86,Q86X55,O14744,Q9Y2K7,Q9H0E3,Q8NB78,Q9BYW2,O14929 13 |
| Organic anion transporters 0.494509516837483 0.0779511114060585 0.9378669420420124 1.0 1.0 2 Q9H936 1 |
| Oncogenic mapk signaling 0.2715135738730034 0.0764959383661361 0.9390245452233932 1.0 1.0 26 Q99956,O15164,Q13555,P36507,P51114 5 |
| Mitophagy 0.290252815170659 0.0716897554834583 0.9428488091251126 1.0 1.0 12 O96008,Q15388,Q96HS1,O95140 4 |
| Nucleotide excision repair 0.2701000490458876 0.0701196809340302 0.9440984021367034 1.0 1.0 50 O60306,P18887,P19447,Q9NR33,P15927,Q9NRF9,P18074,P41440,Q99627,P35251 10 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3301575668743084 0.0674052240439358 0.9462591104640228 1.0 1.0 5 P09874,Q93008,P28482,Q9UPN9 4 |
| Anti inflammatory response favouring leishmania parasite infection 0.2955926580225435 0.0646997278917547 0.9484130794812212 1.0 1.0 11 O43865 1 |
| Cardiac conduction 0.3009398928435893 0.0640727441551497 0.9489123042532186 1.0 1.0 9 Q13555 1 |
| Ion homeostasis 0.3009398928435893 0.0640727441551497 0.9489123042532186 1.0 1.0 9 Q13555 1 |
| Hsf1 dependent transactivation 0.2789325643069488 0.0618999435298896 0.9506425124700522 1.0 1.0 13 P42345,Q13555 2 |
| Hur elavl1 binds and stabilizes mrna 0.3257603517772037 0.059940259408473 0.9522032151508656 1.0 1.0 5 P35658,Q01105,O14980,Q15717 4 |
| G0 and early g1 0.3443223443223463 0.0523437311257084 0.958254808656224 1.0 1.0 4 P06493,P24941,P11388 3 |
| Chrebp activates metabolic gene expression 0.3198973983143939 0.0504733013051797 0.9597452247509908 1.0 1.0 5 P53396,P49327,Q99943,O00763 4 |
| Methylation 0.3145016478339245 0.0503651527537841 0.9598314052011414 1.0 1.0 6 P21964 1 |
| Darpp 32 events 0.306197286395304 0.0476576681476552 0.9619890716667496 1.0 1.0 7 P30154,Q14738,P30153,P13861,P17612,P10644 6 |
| Mapk3 erk1 activation 0.4502196193265048 0.0444996855462915 0.9645061026279343 1.0 1.0 2 P06493 1 |
| Rna polymerase i transcription termination 0.2900137702994204 0.041852275010388 0.9666164620585362 1.0 1.0 10 P19447 1 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3093841642228744 0.0409261840267667 0.9673547430960804 1.0 1.0 6 Q92600,Q9UIV1,Q9C0C2,A5YKK6,P06748 5 |
| Formation of apoptosome 0.4352122986822955 0.0369658346929836 0.9705122470768814 1.0 1.0 2 P28482 1 |
| Sumoylation of transcription cofactors 0.2919664904655438 0.0365787701620224 0.9708208711566068 1.0 1.0 8 Q13363,Q92841 2 |
| Downregulation of smad2 3 smad4 transcriptional activity 0.3300366300366323 0.0363850653641409 0.9709753224078151 1.0 1.0 4 P09874,Q93008,Q9UPN9 3 |
| Regulation of pten gene transcription 0.2617654690236126 0.0349217489249207 0.9721421380546108 1.0 1.0 14 P42345 1 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 0.3267399267399286 0.0330717763813312 0.9736173496185152 1.0 1.0 4 P10644,P17612,P46940 3 |
| Aquaporin mediated transport 0.3267399267399286 0.0330717763813312 0.9736173496185152 1.0 1.0 4 P10644,P17612,Q99797 3 |
| Vitamin c ascorbate metabolism 0.4071768582936654 0.0267695818642759 0.978643514675456 1.0 1.0 3 P11166,P78417 2 |
| Deadenylation dependent mrna decay 0.2672973729946606 0.0240988675419908 0.9807737466318868 1.0 1.0 32 Q15477,Q6PGP7,P62312,Q92600,Q96F86,Q9NPI6,Q9NQT5,Q9C0C2,Q15024,O95453 10 |
| Processive synthesis on the lagging strand 0.2799593561827571 0.022646591620284 0.9819321786061416 1.0 1.0 11 P15927 1 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 0.368960468521229 0.0193570203592992 0.9845562967626248 1.0 1.0 2 P63000 1 |
| Diseases of carbohydrate metabolism 0.2826177481105851 0.0190277777179228 0.9848189460041108 1.0 1.0 9 P08236,P46976,P54802 3 |
| Ngf stimulated transcription 0.3605417276720324 0.0183694278718864 0.9853441413503026 1.0 1.0 2 Q14839 1 |
| Formation of fibrin clot clotting cascade 0.3221083455344011 0.0157524909387787 0.9874318504667152 1.0 1.0 2 P42785 1 |
| Intrinsic pathway of fibrin clot formation 0.3221083455344011 0.0157524909387787 0.9874318504667152 1.0 1.0 2 P42785 1 |
| Transport and synthesis of paps 0.2906295754026256 0.0149721110932854 0.988054430012388 1.0 1.0 2 Q8TB61 1 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 0.3529842548517027 0.006916179874222 0.9944817308517196 1.0 1.0 3 P19838,Q08211 2 |
| Sialic acid metabolism 0.3324932194394506 0.003146670938901 0.9974893239831836 1.0 1.0 3 P16278 1 |
| Incretin synthesis secretion and inactivation 0.2846153846153868 0.0016864783032345 0.9986543856375882 1.0 1.0 4 P35222,Q15005,Q99626 3 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.2846153846153868 0.0016864783032345 0.9986543856375882 1.0 1.0 4 P35222,Q15005,Q99626 3 |
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