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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Electron transport chain oxphos system in mitochondria 0.5737077764509722 3.147072798290185 0.0016491389697808 0.6388127231902303 0.0251156323059712 48 P13073,O14548,Q7KZN9,P24539,O75964,P21912,P12236,P56385,Q9Y6M9,O75880,P00403,O96000,O14949,O43676,P22695,P51970 16
Ferroptosis 0.6132452123997557 2.726668125052914 0.006397735068256 0.9809384844980792 0.0763863688091775 27 P37268,Q9Y277,P16435,P09601,P45880,Q9UKU0,Q96QD8 7
Nonalcoholic fatty liver disease 0.5121246043709661 2.7246099523813503 0.0064377490730587 0.98140629100361 0.0763863688091775 52 P13073,Q9NX14,O14548,P21912,P49327,Q9Y6M9,Q9P0J0,P00403,P31751,O96000,Q96GC9,O14949,Q86Y39,O43676,P22695,P51970 16
Mitochondrial complex iv assembly 0.836626144430293 2.6917829275340965 0.0071071187134279 0.9877318543391402 0.0812054119663897 10 P13073,Q9Y2R0,P00403,Q7KZN9 4
Sphingolipid metabolism overview 0.8334340197499306 2.5190355551113393 0.0117676773189534 0.9993269665813298 0.1083680135193176 9 Q16739,P27544,O95470,Q96G23,Q06136,Q9NRA0 6
Sphingolipid metabolism integrated pathway 0.8334340197499306 2.5190355551113393 0.0117676773189534 0.9993269665813298 0.1083680135193176 9 Q16739,P27544,O95470,Q96G23,Q06136,Q9NRA0 6
Sphingolipid pathway 0.747038921838783 2.4202109439751394 0.0155115060083617 0.9999352905324108 0.1278986890675702 11 Q16739,P04062,O95470,Q96G23,Q06136,Q9NRA0 6
Mitochondrial complex i assembly model oxphos system 0.5640526833331263 2.4059470226788893 0.0161306037018951 0.9999561057336857 0.1289471846269798 28 Q9NX14,Q8IUX1,Q9Y6M9,Q9P0J0,O96000,O95299,O43676,Q96CU9,Q9NPL8,P51970 10
Oxidation by cytochrome p450 0.9353636555891874 2.3864381262499466 0.0170124698463307 0.999974758144386 0.1295888135208157 6 O43169,Q16850,Q6UW02 3
Zinc homeostasis 0.8603276927209389 2.3565505923436465 0.0184455548329416 0.9999897392002396 0.136476313953533 2 Q8TAD4 1
Influence of laminopathies on wnt signaling 0.7420964545723193 2.2377903310169183 0.025234731246938 0.9999998583133854 0.1656364806314978 10 O60725,O75844 2
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6701638370068334 2.204410995051753 0.0274954531220188 0.9999999661824456 0.1748937585184085 14 P42167,P42166,O75844,P50402,O60725 5
Urea cycle and related diseases 0.8189632017190618 2.1704485453735427 0.0299728826034679 0.999999992991081 0.1802501712465713 2 Q9Y619 1
Liver x receptor pathway 0.8117109857641636 2.1374692967826916 0.0325598403870963 0.9999999986507986 0.1931675146042159 2 P49327 1
Metabolism of spingolipids in er and golgi apparatus 0.8826490183248983 2.107962535657778 0.0350342301856163 0.9999999997221264 0.2001492594863452 5 Q16739,O95470,Q9NRA0 3
Statin inhibition of cholesterol production 0.8612215244159065 2.0814288939187047 0.0373946662590805 0.9999999999386832 0.2056045014768139 6 P37268,Q8WTV0,Q14534 3
Nuclear receptors in lipid metabolism and toxicity 0.7988181573999495 2.078587493520019 0.0376552814698216 0.9999999999481174 0.2056045014768139 2 P08183 1
Sphingolipid metabolism in senescence 0.6593092761360932 2.02015785961539 0.0433670158172418 0.999999999998682 0.2306676617175711 12 Q06136,Q16739,Q96G23,P04062 4
Kennedy pathway from sphingolipids 0.8505376344086129 1.975288101520727 0.048235462737828 0.9999999999999434 0.2480106709103327 5 P35790,P48651,O95470,Q9UG56 4
Familial partial lipodystrophy fpld 0.7860858849718314 1.9520599502273115 0.0509310874237121 0.99999999999999 0.2589804649983292 7 O60725,O75844 2
Cholesterol biosynthesis with skeletal dysplasias 0.7797487198521416 1.9237466887667305 0.0543863426930899 0.999999999999999 0.268450987533092 7 Q16850,Q15392,Q15125,Q14739 4
Metapathway biotransformation phase i and ii 0.5080768501602706 1.873264737897003 0.0610318366261286 1.0 0.2701519829280072 24 Q16850,P21964,Q8NCH0,Q7LGA3,Q6UW02 5
Glycerophospholipid biosynthetic pathway 0.697360396697608 1.8713349644044963 0.0612986671149449 1.0 0.2701519829280072 9 Q9HCL2,P48651,Q9BTU6,O95674,O15228,Q86UL3,Q32NB8 7
Vitamin d metabolism 0.8508376850559886 1.8578091895277995 0.0631961156853102 1.0 0.2765390310484852 3 P04062 1
Cholesterol metabolism with bloch and kandutschrussell pathways 0.4874752372561068 1.817897756568868 0.0690797612786446 1.0 0.2900058439275539 28 O95864,Q16850,P37268,Q14739,O75845,P49327,Q15800,Q14534,Q15738,P35610,Q15392,Q15125,O00767 13
Progeriaassociated lipodystrophy 0.6576598399170359 1.8105242453610344 0.0702145279703176 1.0 0.2900058439275539 10 O75844 1
Oxidative phosphorylation 0.4778191406357634 1.8012623093367943 0.0716615455054201 1.0 0.2900058439275539 30 O75964,P24539,Q9Y6M9,P56385,O75787,O96000,Q86Y39,P51970 8
Triacylglyceride synthesis 0.8083053066353293 1.798173257421088 0.0721495560371678 1.0 0.2900058439275539 5 Q9NUQ2,O15228 2
S1p receptor signal transduction 0.6789226861872898 1.7798555745674205 0.0750995997592434 1.0 0.2934116380393207 9 Q13510,P31751,Q9NRA0 3
Sarscov2 b117 variant antagonises innate immune activation 0.7343540155788357 1.7796320008609774 0.075136205527087 1.0 0.2934116380393207 2 O94826 1
Estrogen receptor pathway 0.8050933005078273 1.6689999885955944 0.0951173820720323 1.0 0.3514217050206225 3 Q9HCL2 1
Proteoglycan biosynthesis 0.6777499804338363 1.6427551838755052 0.1004335960994582 1.0 0.3645148752550925 8 Q96L58,Q8WVQ1,Q8NCH0,O94766,Q8TB61 5
Omega3 omega6 fatty acid synthesis 0.7537639608002413 1.621772696183032 0.1048520266855286 1.0 0.3718028762354665 6 O95864,O15254,Q15067,P33121 4
Copper homeostasis 0.7495612526452429 1.6034158117598052 0.1088428824344953 1.0 0.3748811951729935 6 O75880,Q04656,O43819 3
Omega9 fatty acid synthesis 0.7490202143397172 1.601050815128213 0.1093656647182153 1.0 0.3748811951729935 6 O95864,O00767,P33121,P49327 4
Glycerolipids and glycerophospholipids 0.698220408835491 1.5525639909452158 0.1205273339407091 1.0 0.3969371353207537 7 Q9BVG9,P48651,Q9UG56,Q9HCL2 4
Familial hyperlipidemia type 4 0.772227679525747 1.5515681848610736 0.1207655806377334 1.0 0.3969371353207537 4 Q9UBV2 1
Allograft rejection 0.608156604021195 1.5508117269206274 0.1209468094656429 1.0 0.3969371353207537 10 P49327,P04439,P08183,P08670,P10321 5
Envelope proteins and their potential roles in edmd physiopathology 0.5052438365624732 1.4552932234406344 0.1455881018863152 1.0 0.4381846773846658 18 O60266,Q9BTV4,P42167,P42166,P50402,Q14739 6
Adipogenesis 0.5284701619553692 1.4353069149306978 0.1511996581490766 1.0 0.4400480616885863 15 P49327,Q92879,O14654,P10589,O75844,P43490,P14174,O00767 8
Mitochondrial complex iii assembly 0.6695563744679964 1.419383308975 0.1557872958598001 1.0 0.4512711809647731 7 O14949,Q6DKK2,P08574,P22695 4
Immune response to tuberculosis 0.704335982178126 1.4044451547852916 0.1601863326664587 1.0 0.4575692928481715 6 Q03518,P15260,O60244 3
Intracellular trafficking proteins involved in cmt neuropathy 0.5554708957693286 1.397492331843701 0.1622655709823512 1.0 0.4613726142677914 11 Q9UI14,Q8TB36,Q9NR77,O95140 4
Purinergic signaling 0.7105896382129991 1.3787116524861118 0.1679836753448553 1.0 0.4711178531262535 5 Q96RD7,P04899 2
Reninangiotensinaldosterone system raas 0.7229983879634556 1.3250322099468903 0.1851604683517314 1.0 0.4952823152953601 3 P0DP25,Q13555 2
Acquired partial lipodystrophy barraquersimons syndrome 0.7092179521633646 1.2857100628649505 0.1985442679977886 1.0 0.5061256467271856 4 P20700,O60725,P02545 3
Camkk2 pathway 0.4947873788202145 1.225775366639773 0.2202832195212234 1.0 0.5414930137234855 15 Q13501,O76024,P09601,Q13586 4
Phosphodiesterases in neuronal function 0.6934279030315413 1.2004700984236736 0.2299568188201628 1.0 0.5513063893980763 3 O60266 1
Ketogenesis and ketolysis 0.6201142422137508 1.1874862587346289 0.2350358735858924 1.0 0.5535675339221174 7 P23786 1
Endothelin pathways 0.5623028925768188 1.184159930412548 0.23634976032191 1.0 0.5544783350517813 9 P16615 1
Relationship between inflammation cox2 and egfr 0.6624040670310976 1.1688407563046768 0.2424677963101866 1.0 0.5561779442403251 5 P31751 1
Nanomaterial induced apoptosis 0.6512664134794598 1.1686591161603 0.2425410001548431 1.0 0.5561779442403251 6 Q9NR28,P49327,O95831 3
Cholesterol biosynthesis pathway 0.4900320946492743 1.1465571156810903 0.2515647088877748 1.0 0.5685546717353739 14 Q16850,P37268,Q15800 3
Monoamine transport 0.6773392980885558 1.132805829111014 0.2572958030247065 1.0 0.5707907781501698 3 O15127 1
Vitamin dsensitive calcium signaling in depression 0.6074536990840707 1.1278690982118098 0.2593752061411418 1.0 0.5707907781501698 7 P23634,Q8NB78 2
Autosomal recessive osteopetrosis pathways 0.6597899167248518 1.059222904588559 0.28949827615302 1.0 0.6115981500848874 3 P51798 1
Ppar signaling pathway 0.4383240141735845 1.0542444699016 0.2917710050044912 1.0 0.6115981500848874 19 O95864,P23786,Q15067,O15254,Q9UKU0,P50416,O00767 7
Amyotrophic lateral sclerosis als 0.5335567178152664 1.0344990925548962 0.3009029007995296 1.0 0.6209267217167551 9 Q9BUN8,O96008 2
Mitochondrial immune response to sarscov2 0.4894629239961313 1.023399221162526 0.3061191275049717 1.0 0.6233514906619391 11 Q9Y6M9,Q86UT6 2
Mecp2 and associated rett syndrome 0.4067564467104553 1.0040059194259623 0.3153757603994993 1.0 0.6359047194983368 22 Q03518,P31943,Q05086,Q99640 4
Mitochondrial long chain fatty acid betaoxidation 0.4577207000014761 0.9485648458595316 0.3428419775193083 1.0 0.6650320468202888 14 P33121,P23786,P49748,Q9BY49,P40939,P50416 6
Mammary gland development pathway involution stage 4 of 4 0.5578834273435329 0.9422605286955036 0.3460592712816437 1.0 0.6651668859214148 2 P04637 1
Nephrotic syndrome 0.4485115772280813 0.934916909842994 0.3498311218225129 1.0 0.6686447837677183 15 O75844,Q14108 2
Vitamin d receptor pathway 0.4361496039428537 0.9028394670765656 0.3666111012618289 1.0 0.6845404677422886 16 Q92604,Q5VV42,Q96KA5,P08183 4
Overview of interferonsmediated signaling pathway 0.6169121934353075 0.8967517891695189 0.3698513787808661 1.0 0.6845404677422886 4 P23458,P15260 2
Ccl18 signaling pathway 0.4604852278197027 0.8585348649429069 0.3905971871578733 1.0 0.7151289747074416 11 Q96GC9,P00403,Q86UE4 3
Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.4597197715113104 0.8541931171885171 0.3929979961743663 1.0 0.715279538759835 11 Q86UE4,P56545 2
Nad metabolism 0.6037650174406096 0.8423240269651173 0.3996066056120013 1.0 0.7196120656485449 4 Q8IXJ6 1
Degradation pathway of sphingolipids including diseases 0.5129202111402333 0.8267936548576972 0.4083540270583274 1.0 0.7230337306085306 8 Q99519,P17900,O43681,P16278 4
Cell migration and invasion through p75ntr 0.5284488348731337 0.7584481727257775 0.4481827284178112 1.0 0.7681353984271933 7 Q9ULH0,P31751 2
Apoptosis modulation by hsp70 0.5619724532396864 0.6729705081303384 0.5009660535813263 1.0 0.8260284930870276 4 O95831 1
Nad biosynthetic pathways 0.5458090302865558 0.66939677895077 0.5032424057870162 1.0 0.8260284930870276 5 Q8IXJ6 1
Glycosylation and related congenital defects 0.4261811731734528 0.665540448570379 0.5057048813768024 1.0 0.8269471051803857 11 Q9BT22,Q2TAA5,Q9H0U3 3
Cancer immunotherapy by ctla4 blockade 0.4963738920225604 0.663416809869153 0.507063642850849 1.0 0.8269471051803857 2 O00459 1
Type iii interferon signaling 0.4955680902497845 0.6599104223021565 0.5093113155236333 1.0 0.8269607412581099 2 P23458 1
Osx and mirnas in tooth development 0.4872414719312322 0.6239707906152685 0.532646767979069 1.0 0.8373590619979379 2 Q04721 1
Pparalpha pathway 0.4451646763107412 0.5811562817751255 0.5611351293315172 1.0 0.854865122956904 9 P23786 1
Regulation of apoptosis by parathyroid hormonerelated protein 0.5204012735624088 0.5663793811530765 0.5711359081807932 1.0 0.8615913333680915 5 Q07820 1
Alzheimers disease and mirna effects 0.2920769627602128 0.5478443964094553 0.5837987512302714 1.0 0.8707902106732679 90 Q9Y277,O95197,P45880,P16615,P12236,P31751,P49721,P21796,P25787,Q96GC9,Q9NSK0,Q9NQC3 12
Apoptosis modulation and signaling 0.3789003601246299 0.5380209087406839 0.5905626137003028 1.0 0.8707902106732679 16 P49327,O95831,Q9NR28,O43464,Q07820 5
Vitamin a and carotenoid metabolism 0.5117187688359865 0.5320543803034358 0.5946883322773255 1.0 0.8707902106732679 5 Q8WTV0 1
Circadian rhythm genes 0.3058750337021228 0.4980077900440029 0.6184785515098135 1.0 0.8869248329318719 45 P54802,P49327,Q13616,P00813,Q05086,P50416,Q03164,P43490 8
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3745022746244106 0.4780693671162824 0.6326008340491618 1.0 0.8972752059961674 15 P08670,Q13501,Q13616 3
Thiamine metabolic pathways 0.4940030753281607 0.4636899966832374 0.6428698651367806 1.0 0.8990275752572704 5 Q9HC21 1
Molybdenum cofactor moco biosynthesis 0.503761418592145 0.4460871287658398 0.6555343099280535 1.0 0.8990275752572704 3 Q9NZB8,Q969Z3 2
Alzheimers disease 0.286626345457499 0.4427618721649802 0.6579379842969924 1.0 0.8990275752572704 87 Q9Y277,O95197,P45880,P16615,P12236,P31751,P49721,P21796,P25787,Q9NSK0,Q9NQC3 11
P53 transcriptional gene network 0.4143445556124093 0.4317868541887477 0.6658963347650124 1.0 0.9002480663481214 9 Q7LG56,P11166,Q9NQ88,P49327 4
Fatty acid betaoxidation 0.3332033606869862 0.4061347246724324 0.6846436126215896 1.0 0.9064916501878127 21 P50416,P35610,P23786,Q9UKU0 4
Spinal cord injury 0.3459962616961118 0.3887454303731606 0.6974644719200813 1.0 0.9098013825142648 18 P08670,Q9NQC3,P14174 3
Notch signaling 0.4043656548430314 0.3852619657050002 0.7000433376923973 1.0 0.9098013825142648 9 Q04721,P56545,Q92542,O14641 4
Apoptosis 0.3585426967533922 0.3847611913834177 0.7004143544477728 1.0 0.9098013825142648 15 Q07820,Q99590,Q9NR28 3
Neural crest cell migration in cancer 0.4029489489204494 0.3787441834002468 0.7048778397757705 1.0 0.9119810055439888 9 Q9ULH0,P31751 2
Sulfation biotransformation reaction 0.4806555615260508 0.3685664217677214 0.7124509276924798 1.0 0.9143899750725888 3 P11413,O43252 2
Inclusion body myositis 0.4774113101889549 0.3581262577608642 0.7202488296357832 1.0 0.9143899750725888 3 P05067 1
Synaptic signaling pathways associated with autism spectrum disorder 0.3637479044983878 0.3330962543130805 0.7390616267242585 1.0 0.9268313489611129 11 P31751 1
Photodynamic therapyinduced ap1 survival signaling 0.3888856686468361 0.3153498919128605 0.7524960076763572 1.0 0.9341851845801054 9 Q07820 1
Thermogenesis 0.3004838925903504 0.3113462073413676 0.7555374432281381 1.0 0.9349669331905868 31 P50416,O60266,P23786 3
Regulation of sister chromatid separation at the metaphaseanaphase transition 0.3856470562767784 0.3011121483794473 0.7633289776179839 1.0 0.9388719617532404 9 Q12834 1
Nuclear receptors metapathway 0.2760829270708882 0.2864870700263038 0.7745050952784927 1.0 0.9433587231129864 57 Q99735,Q9H2J7,P09601,O00170,P49327,Q9HCL2,Q15043,P23786,P08183,Q13616,P11166,Q13501,Q15067,Q14145,P50416,O00767 16
Tryptophan metabolism 0.3349007370910764 0.2531840693260089 0.800125976391338 1.0 0.958597528997001 15 Q15392,P51648,P35610 3
7oxoc and 7betahc pathways 0.339402860355081 0.2162338868471126 0.8288054404302669 1.0 0.9764867389988044 11 Q15125 1
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.4278419779629048 0.2103935997962734 0.8333604874915617 1.0 0.9775350204986568 4 O00459,Q15118,P42345 3
Angiopoietinlike protein 8 regulatory pathway 0.2848556347123351 0.1964808219899457 0.8442338419468773 1.0 0.9811015208706204 32 O75955,O95819,P42345,P49327,P54646,P18031,Q9Y6R4,P31751,O14654,P11166,P41440,O00767 12
Phosphoinositides metabolism 0.3459701718964737 0.1882100230170236 0.850712015665773 1.0 0.9811015208706204 10 Q9NTJ5 1
Mrna protein and metabolite inducation pathway by cyclosporin a 0.4128530099862815 0.1777692587450898 0.8589041907360655 1.0 0.981386142754008 3 Q14145 1
Cellular proteostasis 0.4054853455229931 0.1760015346060419 0.8602927368263871 1.0 0.981386142754008 6 O15212,P61758,Q9NQP4,O60925,Q9UHV9 5
Steroid biosynthesis 0.4048898441697895 0.159577829152336 0.8732136449194043 1.0 0.986763404606726 3 P56937,P51659 2
Angiogenesis 0.4016657710908023 0.1524874391690293 0.8788024966765047 1.0 0.9888942574089754 3 Q16539,P19174 2
Myometrial relaxation and contraction pathways 0.2880512266833813 0.1429602279699252 0.8863215919651184 1.0 0.9934516010972004 22 P16615,O60266,P78417 3
Cardiac progenitor differentiation 0.3421971528337393 0.1389450715159853 0.8894935544547344 1.0 0.9934516010972004 2 Q16539 1
Nocgmppkg mediated neuroprotection 0.3568876917789583 0.1378568931375409 0.8903535193317729 1.0 0.9934516010972004 8 P30536 1
Disruption of postsynaptic signaling by cnv 0.3453534533700214 0.1377941134057727 0.890403136801867 1.0 0.9934516010972004 9 Q14168,Q13555 2
Glycosaminoglycan degradation 0.3526497952073311 0.1233973058929956 0.9017924903563792 1.0 1.0 8 P54802,P08236 2
Il9 signaling pathway 0.3409580193756696 0.1217626439058185 0.903086999598705 1.0 1.0 9 P62993,P50750,P40763,P27361,P28482,P42224,P23458,O00459 8
Pdgfrbeta pathway 0.3409580193756695 0.1217626439058179 0.9030869995987054 1.0 1.0 9 P62993,P40763,P27361,P17252,P19174,P42224,P23458,P19525 8
Mthfr deficiency 0.349925999499455 0.1142863501234626 0.9090108026232953 1.0 1.0 8 P21964 1
Hedgehog signaling pathway wp47 0.3799032778076209 0.1088427760544462 0.913327194956427 1.0 1.0 3 Q96ST3,Q2M1P5 2
Regulation of wnt bcatenin signaling by small molecule compounds 0.3787634408602042 0.1026002735111565 0.9182802257561716 1.0 1.0 5 P35222,P48729,Q07954,O14641 4
Neural crest cell migration during development 0.361640545409801 0.0985294520244928 0.9215118864008922 1.0 1.0 7 P31751 1
Serotonin htr1 group and fos pathway 0.340866290018826 0.0850420925338096 0.932227926894634 1.0 1.0 8 P09471,P04899,Q16539,P27361,P08754,P28482,P63096 7
Complement system in neuronal development and plasticity 0.303337363829504 0.0835182167676544 0.933439493109094 1.0 1.0 14 Q9NR28,P49327,Q5KU26 3
Tca cycle nutrient use and invasiveness of ovarian cancer 0.3688172043010689 0.0804736318477167 0.9358605669423534 1.0 1.0 5 P00533,P23458,P28482,P40763 4
Tgfbeta receptor signaling in skeletal dysplasias 0.3688172043010686 0.0804736318477161 0.935860566942354 1.0 1.0 5 P42224,P23458,P35222,P40763 4
Tgfbeta receptor signaling 0.3688172043010686 0.0804736318477161 0.935860566942354 1.0 1.0 5 P42224,P23458,P35222,P40763 4
Fatty acid transporters 0.3548062196229574 0.0458103866089023 0.9634613801867218 1.0 1.0 6 P33121,Q9UKU0 2
Mirna regulation of prostate cancer signaling pathways 0.3407746100053929 0.0429011875227701 0.9657803021174568 1.0 1.0 7 Q8NCF5,P42345,P62993,P04637,P28482,P35222 6
Il7 signaling pathway 0.3407746100053839 0.0429011875227481 0.9657803021174742 1.0 1.0 7 P40763,P27361,P28482,P42224,P23458,O00459 6
Melatonin metabolism and effects 0.3230518755145911 0.0291791518317834 0.9767217085813658 1.0 1.0 3 P42892 1
T cell receptor and costimulatory signaling 0.3381720430107495 0.022873988846777 0.9817507888591684 1.0 1.0 5 P19174,P48729,Q15118,P17252 4
Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.3406829792955045 0.0174869222782273 0.9860481657627972 1.0 1.0 6 P09543,Q16539,P27361,P28482,P42224 5
Riboflavin and coq disorders 0.3332064989054716 0.0039401558836967 0.9968562185876884 1.0 1.0 6 Q8NI60,Q5T2R2 2
15q112 copy number variation syndrome 0.3149690943294808 0.0014685486602484 0.9988282681183664 1.0 1.0 4 Q06787,Q7L576,Q9BSJ2 3